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Thermo A36742 POROS CaptureSelect

简要描述:Thermo A36742 POROS CaptureSelect
货号: A36742
POROS CaptureSelect AAVX Affinity Resin is engineered to addres

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  • 更新时间:2023-12-29
  • 访  问  量:186

详细介绍

品牌Thermofisher Scientific/赛默飞世尔货号A36742
规格供货周期一周
主要用途科研单位实验用应用领域医疗卫生,食品,化工,生物产业,制药

Thermo A36742 POROS CaptureSelect

Thermo A36742 POROS CaptureSelect

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Thermo Scientific

POROSCaptureSelectAAVX Affinity Resin

货号: A36742

POROS CaptureSelect AAVX Affinity Resin is engineered to address the high selectivity and capacity requirements for large-scale downstream purification of a broad range of naturally occurring and synthetic adeno-associated virus (AAV) serotypes used for gene therapy applications. POROS CaptureSelect AAVX resin has demonstrated binding reactivity towards a set of AAV serotypes that includes AAV1 to AAV8, and AAVrh10 as well as synthetic serotypes.

Thermo A36742 POROS™ CaptureSelect™ AAVX Affinity Resin

Features of POROS CaptureSelect AAVX resin include:

One-step AAV purification from crude material with high purity and yield

High specificity and capacity, maximizing yield by significantly reducing process steps

Superior capacity maintained at high flow rates

Excellent scalability and easier handling and packing due to rigid polymeric bead

Non-animal derived

 

POROS CaptureSelect AAVX Affinity Resin enables a robust, fast, and platformable purification process for wide-ranging AAV serotypes with excellent purity and yield obtained in one step. This resin comes with complete technical and regulatory support.

 

View other viral vector resins and supporting products

 

Main characteristics

 

Matrix: cross-linked poly(styrene-divinylbenzene) POROS beads

Average particle size: 50 µm

Ligand: CaptureSelect AAVX affinity ligand

Binding capacity: >1x1013 genome copies/mL of resin

Elution conditions: acidic elution with 0.1 M glycine, pH 3.0

Mechanical resistance: 100 bar (1,450 psi; 10 MPa)

Formulation buffer: 18% (v/v) ethanol

Free of animal components

CaptureSelect products contain affinity ligands based on recombinant single-domain antibody fragments (VHH) created by a proprietary technology. The VHH affinity ligand is a 12 to 15 kDa fragment comprising the three complementarity-determining regions (CDRs) that form the antigen-binding domain, efficiently produced in the yeast Saccharomyces cerevisiae by a production process free of any animal components (Animal Origin-Free).

货号 单位规格

A36742 250 mL

A36739 10 mL

A36740 25 mL

A36741 50 mL

A36743 1,000 mL

A36744 5,000 mL

A36745 10,000 mL

规格

配基类型:CaptureSelect AAVX affinity ligand

粒径:50 μm

数量:250 mL

产品线:POROS

结合功能:>1x1013 genome copies/mL of resin

运输条件:Wet Ice

基质:Cross-linked poly(styrene-divinylbenzene) POROS beads

色谱柱类型:Affinity

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