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LKT Labs A50334-Aminosalicylic Acid

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LKT Labs 是一家专注于防癌抗癌特殊化学品研究和开发的公司。主要提供:癌症药物、药物发现试剂盒、天然产物、广泛的生命科学研究试剂、定制合成。
美国LKT Labs 是1988年在美国成立的,为全球提供先端的药物研发试剂、试剂盒、委托合成,并为药物生产企业提供原料,最近几年在农药、水产养殖业有很大程度的开发。
LKT Labs A50334-Aminosalicylic Acid

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LKT Labs 是一家专注于防癌抗癌特殊化学品研究和开发的公司。主要提供:癌症药物、药物发现试剂盒、天然产物、广泛的生命科学研究试剂、定制合成。
美国LKT Labs 是1988年在美国成立的,为全球提供先端的药物研发试剂、试剂盒、委托合成,并为药物生产企业提供原料,最近几年在农药、水产养殖业有很大程度的开发。在LKT Labs 可以找到在其他地方找不到的产品。

LKT Labs A5033 4-Aminosalicylic Acid

LKT Labs A5033 4-Aminosalicylic Acid

 

LKT Product ID Name Unit Size Retail Price Short Description Chemical Name Synonym CAS Number Purity Specification Formula Weight Formula SMILES Stability Ship Temp Storage Temp Optical Rotation Solubility References Chemical Hazard Code UN Number

LKT S8044 R,S-Sulforaphane 100 mg 367.5 Synthetic ITC. 1-Isothiocyanato-4-(methylsulfinyl)-butane D,L-Sulforaphane 4478-93-7 ≥98% 177.29 C6H11NOS2 CS(=O)CCCCN=C=S Stable for 2 years at -20°C.  Avoid prolonged contact with moisture and freeze thaw cycles. Ambient -20°C Soluble in ethanol,  methanol, or ethyl acetate.  Miscible with  water and/or DMSO. "Lee JH, Jeong JK, Park SY. Sulforaphane-induced autophagy flux prevents prion protein-mediated neurotoxicity through AMPK pathway. Neuroscience. 2014 Oct 10;278:31-9. PMID: 25130556.

 

Zhang R, Zhang J, Fang L, et al. Neuroprotective effects of sulforaphane on cholinergic neurons in mice with Alzheimer's disease-like lesions. Int J Mol Sci. 2014 Aug 18;15(8):14396-410. PMID: 25196440.

 

Nallasamy P, Si H, Babu PV, et al. Sulforaphane reduces vascular inflammation in mice and prevents TNF-α-induced monocyte adhesion to primary endothelial cells through interfering with the NF-κB pathway. J Nutr Biochem. 2014 Aug;25(8):824-33. PMID: 24880493.

 

Pinz S, Unser S, Rascle A. The natural chemopreventive agent sulforaphane inhibits STAT5 activity. PLoS One. 2014 Jun 9;9(6):e99391. PMID: 24910998.

 

Wu Q, Zong J, Gao L, et al. Sulforaphane protects H9c2 cardiomyocytes from angiotensin II-induced hypertrophy. Herz. 2014 May;39(3):390-6. PMID: 23784363.

 

Kleszczyński K, Ernst IM, Wagner AE, et al. Sulforaphane and phenylethyl isothiocyanate protect human skin against UVR-induced oxidative stress and apoptosis: role of Nrf2-dependent gene expression and antioxidant enzymes. Pharmacol Res. 2013 Dec;78:28-40. PMID: 24121007.

 

Chuang WY, Kung PH, Kuo CY, et al. Sulforaphane prevents human platelet aggregation through inhibiting the phosphatidylinositol 3-kinase/Akt pathway. Thromb Haemost. 2013 Jun;109(6):1120-30. PMID: 23426129.

 

Thakkar A, Sutaria D, Grandhi BK, et al. The molecular mechanism of action of aspirin, curcumin and sulforaphane combinations in the chemoprevention of pancreatic cancer. Oncol Rep. 2013 Apr;29(4):1671-7. PMID: 23404329.

 

Abdull Razis AF, Hanlon N, Soltys E, et al. The naturally occurring aliphatic isothiocyanates sulforaphane and erucin are weak agonists but potent non-competitive antagonists of the aryl hydrocarbon receptor. Arch Toxicol. 2012 Oct;86(10):1505-14. PMID: 22643862.

 

Wu HZ, Fei HJ, Zhao YL, et al. Antibacterial mechanism of sulforaphane on Escherichia coli. Sichuan Da Xue Xue Bao Yi Xue Ban. 2012 May;43(3):386-90. PMID: 22812243.

 

Do DP, Pai SB, Rizvi SA, et al. Development of sulforaphane-encapsulated microspheres for cancer epigenetic therapy. Int J Pharm. 2010 Feb 15;386(1-2):114-21. PMID: 19922783.

" Not dangerous goods.

LKT S8044 R,S-Sulforaphane 25 mg 123.9 Synthetic ITC. 1-Isothiocyanato-4-(methylsulfinyl)-butane D,L-Sulforaphane 4478-93-7 ≥98% 177.29 C6H11NOS2 CS(=O)CCCCN=C=S Stable for 2 years at -20°C.  Avoid prolonged contact with moisture and freeze thaw cycles. Ambient -20°C Soluble in ethanol,  methanol, or ethyl acetate.  Miscible with  water and/or DMSO. "Lee JH, Jeong JK, Park SY. Sulforaphane-induced autophagy flux prevents prion protein-mediated neurotoxicity through AMPK pathway. Neuroscience. 2014 Oct 10;278:31-9. PMID: 25130556.

 

Zhang R, Zhang J, Fang L, et al. Neuroprotective effects of sulforaphane on cholinergic neurons in mice with Alzheimer's disease-like lesions. Int J Mol Sci. 2014 Aug 18;15(8):14396-410. PMID: 25196440.

 

Nallasamy P, Si H, Babu PV, et al. Sulforaphane reduces vascular inflammation in mice and prevents TNF-α-induced monocyte adhesion to primary endothelial cells through interfering with the NF-κB pathway. J Nutr Biochem. 2014 Aug;25(8):824-33. PMID: 24880493.

 

Pinz S, Unser S, Rascle A. The natural chemopreventive agent sulforaphane inhibits STAT5 activity. PLoS One. 2014 Jun 9;9(6):e99391. PMID: 24910998.

 

Wu Q, Zong J, Gao L, et al. Sulforaphane protects H9c2 cardiomyocytes from angiotensin II-induced hypertrophy. Herz. 2014 May;39(3):390-6. PMID: 23784363.

 

Kleszczyński K, Ernst IM, Wagner AE, et al. Sulforaphane and phenylethyl isothiocyanate protect human skin against UVR-induced oxidative stress and apoptosis: role of Nrf2-dependent gene expression and antioxidant enzymes. Pharmacol Res. 2013 Dec;78:28-40. PMID: 24121007.

 

Chuang WY, Kung PH, Kuo CY, et al. Sulforaphane prevents human platelet aggregation through inhibiting the phosphatidylinositol 3-kinase/Akt pathway. Thromb Haemost. 2013 Jun;109(6):1120-30. PMID: 23426129.

 

Thakkar A, Sutaria D, Grandhi BK, et al. The molecular mechanism of action of aspirin, curcumin and sulforaphane combinations in the chemoprevention of pancreatic cancer. Oncol Rep. 2013 Apr;29(4):1671-7. PMID: 23404329.

 

Abdull Razis AF, Hanlon N, Soltys E, et al. The naturally occurring aliphatic isothiocyanates sulforaphane and erucin are weak agonists but potent non-competitive antagonists of the aryl hydrocarbon receptor. Arch Toxicol. 2012 Oct;86(10):1505-14. PMID: 22643862.

 

Wu HZ, Fei HJ, Zhao YL, et al. Antibacterial mechanism of sulforaphane on Escherichia coli. Sichuan Da Xue Xue Bao Yi Xue Ban. 2012 May;43(3):386-90. PMID: 22812243.

 

Do DP, Pai SB, Rizvi SA, et al. Development of sulforaphane-encapsulated microspheres for cancer epigenetic therapy. Int J Pharm. 2010 Feb 15;386(1-2):114-21. PMID: 19922783.

" Not dangerous goods.

LKT S8044 R,S-Sulforaphane 500 mg 1239 Synthetic ITC. 1-Isothiocyanato-4-(methylsulfinyl)-butane D,L-Sulforaphane 4478-93-7 ≥98% 177.29 C6H11NOS2 CS(=O)CCCCN=C=S Stable for 2 years at -20°C.  Avoid prolonged contact with moisture and freeze thaw cycles. Ambient -20°C Soluble in ethanol,  methanol, or ethyl acetate.  Miscible with  water and/or DMSO. "Lee JH, Jeong JK, Park SY. Sulforaphane-induced autophagy flux prevents prion protein-mediated neurotoxicity through AMPK pathway. Neuroscience. 2014 Oct 10;278:31-9. PMID: 25130556.

 

Zhang R, Zhang J, Fang L, et al. Neuroprotective effects of sulforaphane on cholinergic neurons in mice with Alzheimer's disease-like lesions. Int J Mol Sci. 2014 Aug 18;15(8):14396-410. PMID: 25196440.

 

Nallasamy P, Si H, Babu PV, et al. Sulforaphane reduces vascular inflammation in mice and prevents TNF-α-induced monocyte adhesion to primary endothelial cells through interfering with the NF-κB pathway. J Nutr Biochem. 2014 Aug;25(8):824-33. PMID: 24880493.

 

Pinz S, Unser S, Rascle A. The natural chemopreventive agent sulforaphane inhibits STAT5 activity. PLoS One. 2014 Jun 9;9(6):e99391. PMID: 24910998.

 

Wu Q, Zong J, Gao L, et al. Sulforaphane protects H9c2 cardiomyocytes from angiotensin II-induced hypertrophy. Herz. 2014 May;39(3):390-6. PMID: 23784363.

 

Kleszczyński K, Ernst IM, Wagner AE, et al. Sulforaphane and phenylethyl isothiocyanate protect human skin against UVR-induced oxidative stress and apoptosis: role of Nrf2-dependent gene expression and antioxidant enzymes. Pharmacol Res. 2013 Dec;78:28-40. PMID: 24121007.

 

Chuang WY, Kung PH, Kuo CY, et al. Sulforaphane prevents human platelet aggregation through inhibiting the phosphatidylinositol 3-kinase/Akt pathway. Thromb Haemost. 2013 Jun;109(6):1120-30. PMID: 23426129.

 

Thakkar A, Sutaria D, Grandhi BK, et al. The molecular mechanism of action of aspirin, curcumin and sulforaphane combinations in the chemoprevention of pancreatic cancer. Oncol Rep. 2013 Apr;29(4):1671-7. PMID: 23404329.

 

Abdull Razis AF, Hanlon N, Soltys E, et al. The naturally occurring aliphatic isothiocyanates sulforaphane and erucin are weak agonists but potent non-competitive antagonists of the aryl hydrocarbon receptor. Arch Toxicol. 2012 Oct;86(10):1505-14. PMID: 22643862.

 

Wu HZ, Fei HJ, Zhao YL, et al. Antibacterial mechanism of sulforaphane on Escherichia coli. Sichuan Da Xue Xue Bao Yi Xue Ban. 2012 May;43(3):386-90. PMID: 22812243.

 

Do DP, Pai SB, Rizvi SA, et al. Development of sulforaphane-encapsulated microspheres for cancer epigenetic therapy. Int J Pharm. 2010 Feb 15;386(1-2):114-21. PMID: 19922783.

" Not dangerous goods.

LKT S8044 R,S-Sulforaphane 50 mg 204.8 Synthetic ITC. 1-Isothiocyanato-4-(methylsulfinyl)-butane D,L-Sulforaphane 4478-93-7 ≥98% 177.29 C6H11NOS2 CS(=O)CCCCN=C=S Stable for 2 years at -20°C.  Avoid prolonged contact with moisture and freeze thaw cycles. Ambient -20°C Soluble in ethanol,  methanol, or ethyl acetate.  Miscible with  water and/or DMSO. "Lee JH, Jeong JK, Park SY. Sulforaphane-induced autophagy flux prevents prion protein-mediated neurotoxicity through AMPK pathway. Neuroscience. 2014 Oct 10;278:31-9. PMID: 25130556.

 

Zhang R, Zhang J, Fang L, et al. Neuroprotective effects of sulforaphane on cholinergic neurons in mice with Alzheimer's disease-like lesions. Int J Mol Sci. 2014 Aug 18;15(8):14396-410. PMID: 25196440.

 

Nallasamy P, Si H, Babu PV, et al. Sulforaphane reduces vascular inflammation in mice and prevents TNF-α-induced monocyte adhesion to primary endothelial cells through interfering with the NF-κB pathway. J Nutr Biochem. 2014 Aug;25(8):824-33. PMID: 24880493.

 

Pinz S, Unser S, Rascle A. The natural chemopreventive agent sulforaphane inhibits STAT5 activity. PLoS One. 2014 Jun 9;9(6):e99391. PMID: 24910998.

 

Wu Q, Zong J, Gao L, et al. Sulforaphane protects H9c2 cardiomyocytes from angiotensin II-induced hypertrophy. Herz. 2014 May;39(3):390-6. PMID: 23784363.

 

Kleszczyński K, Ernst IM, Wagner AE, et al. Sulforaphane and phenylethyl isothiocyanate protect human skin against UVR-induced oxidative stress and apoptosis: role of Nrf2-dependent gene expression and antioxidant enzymes. Pharmacol Res. 2013 Dec;78:28-40. PMID: 24121007.

 

Chuang WY, Kung PH, Kuo CY, et al. Sulforaphane prevents human platelet aggregation through inhibiting the phosphatidylinositol 3-kinase/Akt pathway. Thromb Haemost. 2013 Jun;109(6):1120-30. PMID: 23426129.

 

Thakkar A, Sutaria D, Grandhi BK, et al. The molecular mechanism of action of aspirin, curcumin and sulforaphane combinations in the chemoprevention of pancreatic cancer. Oncol Rep. 2013 Apr;29(4):1671-7. PMID: 23404329.

 

Abdull Razis AF, Hanlon N, Soltys E, et al. The naturally occurring aliphatic isothiocyanates sulforaphane and erucin are weak agonists but potent non-competitive antagonists of the aryl hydrocarbon receptor. Arch Toxicol. 2012 Oct;86(10):1505-14. PMID: 22643862.

 

Wu HZ, Fei HJ, Zhao YL, et al. Antibacterial mechanism of sulforaphane on Escherichia coli. Sichuan Da Xue Xue Bao Yi Xue Ban. 2012 May;43(3):386-90. PMID: 22812243.

 

Do DP, Pai SB, Rizvi SA, et al. Development of sulforaphane-encapsulated microspheres for cancer epigenetic therapy. Int J Pharm. 2010 Feb 15;386(1-2):114-21. PMID: 19922783.

" Not dangerous goods.

LKT S8046 R-Sulforaphane 10 mg 231 ITC found in cruciferous vegetables; AhR antagonist. 1-Isothiocyanato-4-(methylsulfinyl)-butane L-Sulforaphane 142825-10-3 ≥98% 177.29 C6H11NOS2 CS(=O)CCCCN=C=S Ambient -20°C Soluble in ethanol,  methanol, or ethyl acetate.  Miscible with  water and/or DMSO. "Abdull Razis AF, Hanlon N, Soltys E, et al. The naturally occurring aliphatic isothiocyanates sulforaphane and erucin are weak agonists but potent non-competitive antagonists of the aryl hydrocarbon receptor. Arch Toxicol. 2012 Oct;86(10):1505-14. PMID: 22643862.

 

Zanichelli F, Capasso S, Cipollaro M, et al. Dose-dependent effects of R-sulforaphane isothiocyanate on the biology of human mesenchymal stem cells, at dietary amounts, it promotes cell proliferation and reduces senescence and apoptosis, while at anti-cancer drug doses, it has a cytotoxic effect. Age (Dordr). 2012 Apr;34(2):281-93. PMID: 21465338.

 

Abdull Razis AF, Bagatta M, De Nicola GR, et al. Induction of epoxide hydrolase and glucuronosyl transferase by isothiocyanates and intact glucosinolates in precision-cut rat liver slices: importance of side-chain substituent and chirality. Arch Toxicol. 2011 Aug;85(8):919-27. PMID: 21132492.

 

Abdull Razis AF, Iori R, Ioannides C. The natural chemopreventive phytochemical R-sulforaphane is a far more potent inducer of the carcinogen-detoxifying enzyme systems in rat liver and lung than the S-isomer. Int J Cancer. 2011 Jun 15;128(12):2775-82. PMID: 20726001.

" Not dangerous goods.

LKT S8049 S-Sulforaphene 10 mg 257.3 ITC found in cruciferous vegetables. (-)4-Isothiocyanato-4R-(methylsulfinyl)-1-butene Raphanin; Sativin 592-95-0 ≥98% 175.27 C6H9NOS2 CS(=O)C=CCCN=C=S Ambient -20°C Soluble in water, methanol, DMSO, or chloroform. "Kim KH, Moon E, Kim SY, et al. 4-Methylthio-butanyl derivatives from the seeds of Raphanus sativus and their biological evaluation on anti-inflammatory and antitumor activities. J Ethnopharmacol. 2014;151(1):503-8. PMID: 24231071.

 

Beevi SS, Mangamoori LN, Subathra M, et al. Hexane extract of Raphanus sativus L. roots inhibits cell proliferation and induces apoptosis in human cancer cells by modulating genes related to apoptotic pathway. Plant Foods Hum Nutr. 2010 Sep;65(3):200-9. PMID: 20652750.

 

Brinker AM, Spencer GF. Herbicidal activity of sulforaphene from stock (Matthiola incana). J Chem Ecol. 1993 Oct;19(10):2279-84. PMID: 24248575.

" Not dangerous goods.

LKT S8145 Sulindac 5 g 60.7 NSAID; COX-1/2 and PDE inhibitor. (Z)-5-Fluoro-2-methyl-1-((p-(methylsulfinyl) phenyl)methylene)-1H-indene-3-acetic acid  Arthrocine; Sulindac sulfoxide; Clinoril; Clisundac; Reumofil 38194-50-2 ≥98% 356.42 C20H17FO3S CC1=C(C2=C(C1=CC3=CC=C(C=C3)S(=O)C)C=CC(=C2)F)CC(=O)O Ambient Ambient Soluble in DMSO (100 mM) or ethanol (25 mM). "Modi JP, Gharibani PM, Ma Z, et al. Protective mechanism of sulindac in an animal model of ischemic stroke. Brain Res. 2014 Aug 12;1576:91-9. PMID: 24968090.

 

Li N, Xi Y, Tinsley HN, et al. Sulindac selectively inhibits colon tumor cell growth by activating the cGMP/PKG pathway to suppress Wnt/β-catenin signaling. Mol Cancer Ther. 2013 Sep;12(9):1848-59. PMID: 23804703.

 

Li X, Gao L, Cui Q, et al. Sulindac inhibits tumor cell invasion by suppressing NF-κB-mediated transcription of microRNAs. Oncogene. 2012 Nov 29;31(48):4979-86. PMID: 22286762.

 

Scheper MA, Nikitakis NG, Chaisuparat R, et al. Sulindac induces apoptosis and inhibits tumor growth in vivo in head and neck squamous cell carcinoma. Neoplasia. 2007 Mar;9(3):192-9. PMID: 17401459.

" Xn "UN number: 2811     Class:  6.1     Packing group:  III

Proper shipping name:  Toxic solids, organic, n.o.s. (Sulindac)

Marine pollutant:  No     Poison inhalation hazard:  No"

LKT S8046 R-Sulforaphane 25 mg 451.5 ITC found in cruciferous vegetables; AhR antagonist. 1-Isothiocyanato-4-(methylsulfinyl)-butane L-Sulforaphane 142825-10-3 ≥98% 177.29 C6H11NOS2 CS(=O)CCCCN=C=S Ambient -20°C Soluble in ethanol,  methanol, or ethyl acetate.  Miscible with  water and/or DMSO. "Abdull Razis AF, Hanlon N, Soltys E, et al. The naturally occurring aliphatic isothiocyanates sulforaphane and erucin are weak agonists but potent non-competitive antagonists of the aryl hydrocarbon receptor. Arch Toxicol. 2012 Oct;86(10):1505-14. PMID: 22643862.

 

Zanichelli F, Capasso S, Cipollaro M, et al. Dose-dependent effects of R-sulforaphane isothiocyanate on the biology of human mesenchymal stem cells, at dietary amounts, it promotes cell proliferation and reduces senescence and apoptosis, while at anti-cancer drug doses, it has a cytotoxic effect. Age (Dordr). 2012 Apr;34(2):281-93. PMID: 21465338.

 

Abdull Razis AF, Bagatta M, De Nicola GR, et al. Induction of epoxide hydrolase and glucuronosyl transferase by isothiocyanates and intact glucosinolates in precision-cut rat liver slices: importance of side-chain substituent and chirality. Arch Toxicol. 2011 Aug;85(8):919-27. PMID: 21132492.

 

Abdull Razis AF, Iori R, Ioannides C. The natural chemopreventive phytochemical R-sulforaphane is a far more potent inducer of the carcinogen-detoxifying enzyme systems in rat liver and lung than the S-isomer. Int J Cancer. 2011 Jun 15;128(12):2775-82. PMID: 20726001.

" Not dangerous goods.

LKT S8146 Sulindac Sulfone 50 mg 123.8 NSAID; COX-1/2 and PDE inhibitor. 5-Fluoro-2-methy l-1-((4-(methylsulfonyl) phenyl)- methylene)-1H-indene-3-acetic acid 59864-04-9 ≥98% 372.41 C20H17FO4S CC1=C(C2=C(C1=CC3=CC=C(C=C3)S(=O)(=O)C)C=CC(=C2)F)CC(=O)O Ambient Ambient Soluble in DMSO or ethanol. "Modi JP, Gharibani PM, Ma Z, et al. Protective mechanism of sulindac in an animal model of ischemic stroke. Brain Res. 2014 Aug 12;1576:91-9. PMID: 24968090.

 

Li N, Xi Y, Tinsley HN, et al. Sulindac selectively inhibits colon tumor cell growth by activating the cGMP/PKG pathway to suppress Wnt/β-catenin signaling. Mol Cancer Ther. 2013 Sep;12(9):1848-59. PMID: 23804703.

 

Li X, Gao L, Cui Q, et al. Sulindac inhibits tumor cell invasion by suppressing NF-κB-mediated transcription of microRNAs. Oncogene. 2012 Nov 29;31(48):4979-86. PMID: 22286762.

 

Scheper MA, Nikitakis NG, Chaisuparat R, et al. Sulindac induces apoptosis and inhibits tumor growth in vivo in head and neck squamous cell carcinoma. Neoplasia. 2007 Mar;9(3):192-9. PMID: 17401459.

" Not dangerous goods.

LKT S8146 Sulindac Sulfone 250 mg 356.7 NSAID; COX-1/2 and PDE inhibitor. 5-Fluoro-2-methy l-1-((4-(methylsulfonyl) phenyl)- methylene)-1H-indene-3-acetic acid 59864-04-9 ≥98% 372.41 C20H17FO4S CC1=C(C2=C(C1=CC3=CC=C(C=C3)S(=O)(=O)C)C=CC(=C2)F)CC(=O)O Ambient Ambient Soluble in DMSO or ethanol. "Modi JP, Gharibani PM, Ma Z, et al. Protective mechanism of sulindac in an animal model of ischemic stroke. Brain Res. 2014 Aug 12;1576:91-9. PMID: 24968090.

 

Li N, Xi Y, Tinsley HN, et al. Sulindac selectively inhibits colon tumor cell growth by activating the cGMP/PKG pathway to suppress Wnt/β-catenin signaling. Mol Cancer Ther. 2013 Sep;12(9):1848-59. PMID: 23804703.

 

Li X, Gao L, Cui Q, et al. Sulindac inhibits tumor cell invasion by suppressing NF-κB-mediated transcription of microRNAs. Oncogene. 2012 Nov 29;31(48):4979-86. PMID: 22286762.

 

Scheper MA, Nikitakis NG, Chaisuparat R, et al. Sulindac induces apoptosis and inhibits tumor growth in vivo in head and neck squamous cell carcinoma. Neoplasia. 2007 Mar;9(3):192-9. PMID: 17401459.

" Not dangerous goods.

LKT T1849 Temozolomide 25 mg 81.6 Imidazotetrazine, DNA alkylator. 3,4-Dihydro-3-methyl-4-oxoimidazo[5,1-d]-1,2,3,5- tetrazine-8-carboxamide Methazolastone; Temodal; Temodar 85622-93-1 ≥98% 194.15 C6H6N6O2 CN1C(=O)N2C=NC(=C2N=N1)C(=O)N "Temozolomide was unstable at 37°C in human plasma with a degradation t1/2 of 15 min; however, it was stable at 4°C for at least 30 min. Temozolomide was stable in acidified human plasma (pH < 4) for at least 24 h at 25°C, and for at least 30 days at -20°C. Moreover, temozolomide was stable in acidified human plasma after being subjected to three freeze thaw cycles. 

J Pharm Biomed Anal. 2001 Jan;24(3):461-8" Ambient 4°C Soluble in DMSO to 39mg/mL, Water to 5 mg/mL, Ethanol <1mg/mL "Nagasawa DT, Chow F, Yew A, et al. Temozolomide and other potential agents for the treatment of glioblastoma multiforme. Neurosurg Clin N Am. 2012 Apr;23(2):307-22, ix. PMID: 22440874.

 

Wesolowski JR, Rajdev P, Mukherji SK. Temozolomide (Temodar). AJNR Am J Neuroradiol. 2010 Sep;31(8):1383-4. PMID: 2053882.

 

Friedman HS, Kerby T, Calvert H. Temozolomide and treatment of malignant glioma. Clin Cancer Res. 2000 Jul;6(7):2585-97. PMID: 10914698.

 

Horing E, Harter PN, Seznec J, et al. The “go or grow” potential of gliomas is linked to the necropeptide processing enzyme carboxypeptidase E and mediated by metabolic stress. Acta Neuropathol. 2012 Jul;124(1):83-97. PMID: 22249620.

 

Momiyama M, Suetsugu A, Chishima T, et al. Subcellular real-time imaging of the efficacy of temozolomide on cancer cells in the brain of live mice. Anticancer Res. 2013 Jan;33(1):103-106. PMID: 23267133.

" Repr., Carc., Muta., Xn, Xi Not dangerous goods.

LKT T1849 Temozolomide 100 mg 81.6 Imidazotetrazine, DNA alkylator. 3,4-Dihydro-3-methyl-4-oxoimidazo[5,1-d]-1,2,3,5- tetrazine-8-carboxamide Methazolastone; Temodal; Temodar 85622-93-1 ≥98% 194.15 C6H6N6O2 CN1C(=O)N2C=NC(=C2N=N1)C(=O)N "Temozolomide was unstable at 37°C in human plasma with a degradation t1/2 of 15 min; however, it was stable at 4°C for at least 30 min. Temozolomide was stable in acidified human plasma (pH < 4) for at least 24 h at 25°C, and for at least 30 days at -20°C. Moreover, temozolomide was stable in acidified human plasma after being subjected to three freeze thaw cycles. 

J Pharm Biomed Anal. 2001 Jan;24(3):461-8" Ambient 4°C Soluble in DMSO to 39mg/mL, Water to 5 mg/mL, Ethanol <1mg/mL "Nagasawa DT, Chow F, Yew A, et al. Temozolomide and other potential agents for the treatment of glioblastoma multiforme. Neurosurg Clin N Am. 2012 Apr;23(2):307-22, ix. PMID: 22440874.

 

Wesolowski JR, Rajdev P, Mukherji SK. Temozolomide (Temodar). AJNR Am J Neuroradiol. 2010 Sep;31(8):1383-4. PMID: 2053882.

 

Friedman HS, Kerby T, Calvert H. Temozolomide and treatment of malignant glioma. Clin Cancer Res. 2000 Jul;6(7):2585-97. PMID: 10914698.

 

Horing E, Harter PN, Seznec J, et al. The “go or grow” potential of gliomas is linked to the necropeptide processing enzyme carboxypeptidase E and mediated by metabolic stress. Acta Neuropathol. 2012 Jul;124(1):83-97. PMID: 22249620.

 

Momiyama M, Suetsugu A, Chishima T, et al. Subcellular real-time imaging of the efficacy of temozolomide on cancer cells in the brain of live mice. Anticancer Res. 2013 Jan;33(1):103-106. PMID: 23267133.

" Repr., Carc., Muta., Xn, Xi Not dangerous goods.

LKT S8169 Suramin Hexasodium 50 mg 97.2 RyR agonist, SIRT, telomerase, P2Y, GPCR inhibitor. 8,8'-[Carbonylbis[imino-3,1-phenylenecarbonylimino- (4-methyl-3,1-phenylene)-carbonylimino]]bis-1,3,5- naphthalenetrisulfonic acid hexasodium salt Suramin Sodium; Bayer 205; Antrypol; Germanin; Moranyl; Naganol; Naphuride 129-46-4 ≥98% 1429.19 C51H34N6O23S6Na6 CC1=C(C=C(C=C1)C(=O)NC2=C3C(=CC(=CC3=C(C=C2)S(=O)(=O)[O-])S(=O)(=O)[O-])S(=O)(=O)[O-])NC(=O)C4=CC(=CC=C4)NC(=O)NC5=CC=CC(=C5)C(=O)NC6=C(C=CC(=C6)C(=O)NC7=C8C(=CC(=CC8=C(C=C7)S(=O)(=O)[O-])S(=O)(=O)[O-])S(=O)(=O)[O-])C.[Na+].[Na+].[Na+].[Na+].[Na+].[Na+] Hygroscopic. Ambient 4°C Soluble in water. Sparingly soluble in alcohol. Insoluble in benzene, ether or chloroform. "Wang Y, Qing J, Sun Y, et al. Suramin inhibits EV71 infection. Antiviral Res. 2014 Mar;103:1-6. PMID: 24374150.

 

Marques AF, Esser D, Rosenthal PJ, et al. Falcipain-2 inhibition by suramin and suramin analogues. Bioorg Med Chem. 2013 Jul 1;21(13):3667-73. PMID: 23680445.

 

Sakkiah S, Arooj M, Kumar MR, et al. Identification of inhibitor binding site in human sirtuin 2 using molecular docking and dynamics simulations. PLoS One. 2013;8(1):e51429. PMID: 23382805.

 

Erguven M, Akev N, Ozdemir A, et al. The inhibitory effect of suramin on telomerase activity and spheroid growth of C6 glioma cells. Med Sci Monit. 2008 Aug;14(8):BR165-73. PMID: 18667993.

 

Abbracchio MP, Burnstock G, Boeynaems JM, et al. International Union of Pharmacology LVIII: update on the P2Y G protein-coupled nucleotide receptors: from molecular mechanisms and pathophysiology to therapy. Pharmacol Rev. 2006 Sep;58(3):281-341. PMID: 16968944.

 

Wolner I, Kassack MU, Ullmann H, et al. Use-dependent inhibition of the skeletal muscle ryanodine receptor by the suramin analogue NF676. Br J Pharmacol. 2005 Oct;146(4):525-33. PMID: 16056233.

 

Beindl W, Mitterauer T, Hohenegger M, et al. Inhibition of receptor/G protein coupling by suramin analogues. Mol Pharmacol. 1996 Aug;50(2):415-23. PMID: 8700151.

" Not dangerous goods.

LKT S8169 Suramin Hexasodium 250 mg 396.2 RyR agonist, SIRT, telomerase, P2Y, GPCR inhibitor. 8,8'-[Carbonylbis[imino-3,1-phenylenecarbonylimino- (4-methyl-3,1-phenylene)-carbonylimino]]bis-1,3,5- naphthalenetrisulfonic acid hexasodium salt Suramin Sodium; Bayer 205; Antrypol; Germanin; Moranyl; Naganol; Naphuride 129-46-4 ≥98% 1429.19 C51H34N6O23S6Na6 CC1=C(C=C(C=C1)C(=O)NC2=C3C(=CC(=CC3=C(C=C2)S(=O)(=O)[O-])S(=O)(=O)[O-])S(=O)(=O)[O-])NC(=O)C4=CC(=CC=C4)NC(=O)NC5=CC=CC(=C5)C(=O)NC6=C(C=CC(=C6)C(=O)NC7=C8C(=CC(=CC8=C(C=C7)S(=O)(=O)[O-])S(=O)(=O)[O-])S(=O)(=O)[O-])C.[Na+].[Na+].[Na+].[Na+].[Na+].[Na+] Hygroscopic. Ambient 4°C Soluble in water. Sparingly soluble in alcohol. Insoluble in benzene, ether or chloroform. "Wang Y, Qing J, Sun Y, et al. Suramin inhibits EV71 infection. Antiviral Res. 2014 Mar;103:1-6. PMID: 24374150.

 

Marques AF, Esser D, Rosenthal PJ, et al. Falcipain-2 inhibition by suramin and suramin analogues. Bioorg Med Chem. 2013 Jul 1;21(13):3667-73. PMID: 23680445.

 

Sakkiah S, Arooj M, Kumar MR, et al. Identification of inhibitor binding site in human sirtuin 2 using molecular docking and dynamics simulations. PLoS One. 2013;8(1):e51429. PMID: 23382805.

 

Erguven M, Akev N, Ozdemir A, et al. The inhibitory effect of suramin on telomerase activity and spheroid growth of C6 glioma cells. Med Sci Monit. 2008 Aug;14(8):BR165-73. PMID: 18667993.

 

Abbracchio MP, Burnstock G, Boeynaems JM, et al. International Union of Pharmacology LVIII: update on the P2Y G protein-coupled nucleotide receptors: from molecular mechanisms and pathophysiology to therapy. Pharmacol Rev. 2006 Sep;58(3):281-341. PMID: 16968944.

 

Wolner I, Kassack MU, Ullmann H, et al. Use-dependent inhibition of the skeletal muscle ryanodine receptor by the suramin analogue NF676. Br J Pharmacol. 2005 Oct;146(4):525-33. PMID: 16056233.

 

Beindl W, Mitterauer T, Hohenegger M, et al. Inhibition of receptor/G protein coupling by suramin analogues. Mol Pharmacol. 1996 Aug;50(2):415-23. PMID: 8700151.

" Not dangerous goods.

LKT A0817 D,L-1′-Acetoxychavicol Acetate 25 mg 75.3 Found in Languas and Alpinia; TRPA1 agonist, xanthine oxidase inhibitor. Benzenemethanol, 4-(acetyloxy)-α-ethenyl-, acetate "alphaS)-4-(Acetyloxy)-alpha-ethenylbenzenemethanol

CCRIS 7708" 52946-22-2 ≥98% 234.25 C13H14O4 CC(=O)OC1=CC=C(C=C1)C(C=C)OC(=O)C 2 years. Ambient Ambient Soluble in DMSO and ethanol. "Williams M, Tietzel I, Quick QA. 1'-Acetoxychavicol acetate promotes caspase 3-activated glioblastoma cell death by overcoming enhanced cytokine expression. Oncol Lett. 2013 Jun;5(6):1968-1972. PMID: 23833677.

 

Seo JW, Cho SC, Park SJ, et al. 1'-Acetoxychavicol acetate isolated from Alpinia galanga ameliorates ovalbumin-induced asthma in mice. PLoS One. 2013;8(2):e56447. PMID: 23451048.

 

Aziz AN, Ibrahim H, Rosmy Syamsir D, et al. Antimicrobial compounds from Alpinia conchigera. J Ethnopharmacol. 2013 Feb 13;145(3):798-802. PMID: 23266278.

 

Ohnishi R, Matsui-Yuasa I, Deguchi Y, et al. 1'-acetoxychavicol acetate inhibits adipogenesis in 3T3-L1 adipocytes and in high fat-fed rats. Am J Chin Med. 2012;40(6):1189-204. PMID: 23227791.

 

In LL, Arshad NM, Ibrahim H, et al. 1'-Acetoxychavicol acetate inhibits growth of human oral carcinoma xenograft in mice and potentiates cisplatin effect via proinflammatory microenvironment alterations. BMC Complement Altern Med. 2012 Oct 9;12:179. PMID: 23043547.

 

Batra V, Syed Z, Gill JN, et al. Effects of the tropical ginger compound,1'-acetoxychavicol acetate, against tumor promotion in K5.Stat3C transgenic mice. J Exp Clin Cancer Res. 2012 Jun 15;31:57. PMID: 22704648.

 

Yaku K, Matsui-Yuasa I, Azuma H, et al. 1'-Acetoxychavicol acetate enhances the phase II enzyme activities via the increase in intranuclear Nrf2 level and cytosolic p21 level. Am J Chin Med. 2011;39(4):789-802. PMID: 21721157.

 

Pang X, Zhang L, Lai L, et al. 1'-Acetoxychavicol acetate suppresses angiogenesis-mediated human prostate tumor growth by targeting VEGF-mediated Src-FAK-Rho GTPase-signaling pathway. Carcinogenesis. 2011 Jun;32(6):904-12. PMID: 21427164.

 

Watanabe K, Takatsuki H, Sonoda M, et al. Anti-influenza viral effects of novel nuclear export inhibitors from Valerianae Radix and Alpinia galanga. Drug Discov Ther. 2011 Feb;5(1):26-31. PMID: 22466093.

 

Kaur A, Singh R, Dey CS, et al. Antileishmanial phenylpropanoids from Alpinia galanga (Linn.) Willd. Indian J Exp Biol. 2010 Mar;48(3):314-7. PMID: 21046987.

 

Narukawa M, Koizumi K, Iwasaki Y, et al. Galangal pungent component, 1'-acetoxychavicol acetate, activates TRPA1. Biosci Biotechnol Biochem. 2010;74(8):1694-6. PMID: 20699565.

 

Ichikawa H, Takada Y, Murakami A, et al. Identification of a novel blocker of I kappa B alpha kinase that enhances cellular apoptosis and inhibits cellular invasion through suppression of NF-kappa B-regulated gene products. J Immunol. 2005 Jun 1;174(11):7383-92. PMID: 15905586.

" Not dangerous goods.

LKT A0817 D,L-1′-Acetoxychavicol Acetate 100 mg 279.1 Found in Languas and Alpinia; TRPA1 agonist, xanthine oxidase inhibitor. Benzenemethanol, 4-(acetyloxy)-α-ethenyl-, acetate "alphaS)-4-(Acetyloxy)-alpha-ethenylbenzenemethanol

CCRIS 7708" 52946-22-2 ≥98% 234.25 C13H14O4 CC(=O)OC1=CC=C(C=C1)C(C=C)OC(=O)C 2 years. Ambient Ambient Soluble in DMSO and ethanol. "Williams M, Tietzel I, Quick QA. 1'-Acetoxychavicol acetate promotes caspase 3-activated glioblastoma cell death by overcoming enhanced cytokine expression. Oncol Lett. 2013 Jun;5(6):1968-1972. PMID: 23833677.

 

Seo JW, Cho SC, Park SJ, et al. 1'-Acetoxychavicol acetate isolated from Alpinia galanga ameliorates ovalbumin-induced asthma in mice. PLoS One. 2013;8(2):e56447. PMID: 23451048.

 

Aziz AN, Ibrahim H, Rosmy Syamsir D, et al. Antimicrobial compounds from Alpinia conchigera. J Ethnopharmacol. 2013 Feb 13;145(3):798-802. PMID: 23266278.

 

Ohnishi R, Matsui-Yuasa I, Deguchi Y, et al. 1'-acetoxychavicol acetate inhibits adipogenesis in 3T3-L1 adipocytes and in high fat-fed rats. Am J Chin Med. 2012;40(6):1189-204. PMID: 23227791.

 

In LL, Arshad NM, Ibrahim H, et al. 1'-Acetoxychavicol acetate inhibits growth of human oral carcinoma xenograft in mice and potentiates cisplatin effect via proinflammatory microenvironment alterations. BMC Complement Altern Med. 2012 Oct 9;12:179. PMID: 23043547.

 

Batra V, Syed Z, Gill JN, et al. Effects of the tropical ginger compound,1'-acetoxychavicol acetate, against tumor promotion in K5.Stat3C transgenic mice. J Exp Clin Cancer Res. 2012 Jun 15;31:57. PMID: 22704648.

 

Yaku K, Matsui-Yuasa I, Azuma H, et al. 1'-Acetoxychavicol acetate enhances the phase II enzyme activities via the increase in intranuclear Nrf2 level and cytosolic p21 level. Am J Chin Med. 2011;39(4):789-802. PMID: 21721157.

 

Pang X, Zhang L, Lai L, et al. 1'-Acetoxychavicol acetate suppresses angiogenesis-mediated human prostate tumor growth by targeting VEGF-mediated Src-FAK-Rho GTPase-signaling pathway. Carcinogenesis. 2011 Jun;32(6):904-12. PMID: 21427164.

 

Watanabe K, Takatsuki H, Sonoda M, et al. Anti-influenza viral effects of novel nuclear export inhibitors from Valerianae Radix and Alpinia galanga. Drug Discov Ther. 2011 Feb;5(1):26-31. PMID: 22466093.

 

Kaur A, Singh R, Dey CS, et al. Antileishmanial phenylpropanoids from Alpinia galanga (Linn.) Willd. Indian J Exp Biol. 2010 Mar;48(3):314-7. PMID: 21046987.

 

Narukawa M, Koizumi K, Iwasaki Y, et al. Galangal pungent component, 1'-acetoxychavicol acetate, activates TRPA1. Biosci Biotechnol Biochem. 2010;74(8):1694-6. PMID: 20699565.

 

Ichikawa H, Takada Y, Murakami A, et al. Identification of a novel blocker of I kappa B alpha kinase that enhances cellular apoptosis and inhibits cellular invasion through suppression of NF-kappa B-regulated gene products. J Immunol. 2005 Jun 1;174(11):7383-92. PMID: 15905586.

" Not dangerous goods.

LKT A0817 D,L-1′-Acetoxychavicol Acetate 250 mg 509.7 Found in Languas and Alpinia; TRPA1 agonist, xanthine oxidase inhibitor. Benzenemethanol, 4-(acetyloxy)-α-ethenyl-, acetate "alphaS)-4-(Acetyloxy)-alpha-ethenylbenzenemethanol

CCRIS 7708" 52946-22-2 ≥98% 234.25 C13H14O4 CC(=O)OC1=CC=C(C=C1)C(C=C)OC(=O)C 2 years. Ambient Ambient Soluble in DMSO and ethanol. "Williams M, Tietzel I, Quick QA. 1'-Acetoxychavicol acetate promotes caspase 3-activated glioblastoma cell death by overcoming enhanced cytokine expression. Oncol Lett. 2013 Jun;5(6):1968-1972. PMID: 23833677.

 

Seo JW, Cho SC, Park SJ, et al. 1'-Acetoxychavicol acetate isolated from Alpinia galanga ameliorates ovalbumin-induced asthma in mice. PLoS One. 2013;8(2):e56447. PMID: 23451048.

 

Aziz AN, Ibrahim H, Rosmy Syamsir D, et al. Antimicrobial compounds from Alpinia conchigera. J Ethnopharmacol. 2013 Feb 13;145(3):798-802. PMID: 23266278.

 

Ohnishi R, Matsui-Yuasa I, Deguchi Y, et al. 1'-acetoxychavicol acetate inhibits adipogenesis in 3T3-L1 adipocytes and in high fat-fed rats. Am J Chin Med. 2012;40(6):1189-204. PMID: 23227791.

 

In LL, Arshad NM, Ibrahim H, et al. 1'-Acetoxychavicol acetate inhibits growth of human oral carcinoma xenograft in mice and potentiates cisplatin effect via proinflammatory microenvironment alterations. BMC Complement Altern Med. 2012 Oct 9;12:179. PMID: 23043547.

 

Batra V, Syed Z, Gill JN, et al. Effects of the tropical ginger compound,1'-acetoxychavicol acetate, against tumor promotion in K5.Stat3C transgenic mice. J Exp Clin Cancer Res. 2012 Jun 15;31:57. PMID: 22704648.

 

Yaku K, Matsui-Yuasa I, Azuma H, et al. 1'-Acetoxychavicol acetate enhances the phase II enzyme activities via the increase in intranuclear Nrf2 level and cytosolic p21 level. Am J Chin Med. 2011;39(4):789-802. PMID: 21721157.

 

Pang X, Zhang L, Lai L, et al. 1'-Acetoxychavicol acetate suppresses angiogenesis-mediated human prostate tumor growth by targeting VEGF-mediated Src-FAK-Rho GTPase-signaling pathway. Carcinogenesis. 2011 Jun;32(6):904-12. PMID: 21427164.

 

Watanabe K, Takatsuki H, Sonoda M, et al. Anti-influenza viral effects of novel nuclear export inhibitors from Valerianae Radix and Alpinia galanga. Drug Discov Ther. 2011 Feb;5(1):26-31. PMID: 22466093.

 

Kaur A, Singh R, Dey CS, et al. Antileishmanial phenylpropanoids from Alpinia galanga (Linn.) Willd. Indian J Exp Biol. 2010 Mar;48(3):314-7. PMID: 21046987.

 

Narukawa M, Koizumi K, Iwasaki Y, et al. Galangal pungent component, 1'-acetoxychavicol acetate, activates TRPA1. Biosci Biotechnol Biochem. 2010;74(8):1694-6. PMID: 20699565.

 

Ichikawa H, Takada Y, Murakami A, et al. Identification of a novel blocker of I kappa B alpha kinase that enhances cellular apoptosis and inhibits cellular invasion through suppression of NF-kappa B-regulated gene products. J Immunol. 2005 Jun 1;174(11):7383-92. PMID: 15905586.

" Not dangerous goods.

LKT A0819 Acetylsalicylic Acid 500 g 106.8 "NSAID; COX-1/2 inhibitor.

" 2-(Acetyloxy)benzoic acid Salicylic acid acetate; aspirin 50-78-2 ≥98% 180.16 C9H8O4 CC(=O)OC1=CC=CC=C1C(=O)O 2 yrs Ambient Ambient Soluble in ethanol (200 mg/mL), DMSO or water (3.3 mg/ml). "Algra AM, Rothwell PM. Effects of regular aspirin on long-term cancer incidence and metastasis: a systematic comparison of evidence from observational studies versus randomised trials. Lancet Oncol. 2012 May;13(5):518-27. PMID: 22440112.

 

Bartfai T, Conti B. Fever. ScientificWorldJournal. 2010 Mar 16;10:490-503. PMID: 20305990.

 

Antithrombotic Trialists' (ATT) Collaboration: Baigent C, Blackwell L, Collins R, et al. Aspirin in the primary and secondary prevention of vascular disease: collaborative meta-analysis of individual participant data from randomised trials. Lancet. 2009 May 30;373(9678):1849-60. PMID: 9482214.

 

Tohgi H, Konno S, Tamura K, et al. Effects of low-to-high doses of aspirin on platelet aggregability and metabolites of thromboxane A2 and prostacyclin. Stroke. 1992 Oct;23(10):1400-3. PMID: 1412574.

 

Li W, Li J, Ashok M, et al. A cardiovascular drug rescues mice from lethal sepsis by selectively attentuating a late-acting proinflammatory mediator, high mobility group box 1. J Immunol. 2007 Mar 15;178(6):3856-3864. PMID: 17339485.

" T, Xi "UN number: 2811     Class: 6.1     Packing Group: III

Proper shipping name: Toxic solid, organic, n.o.s. (Acetylsalicylic Acid)"

LKT A0819 Acetylsalicylic Acid 1 kg 131 "NSAID; COX-1/2 inhibitor.

" 2-(Acetyloxy)benzoic acid Salicylic acid acetate; aspirin 50-78-2 ≥98% 180.16 C9H8O4 CC(=O)OC1=CC=CC=C1C(=O)O 2 yrs Ambient Ambient Soluble in ethanol (200 mg/mL), DMSO or water (3.3 mg/ml). "Algra AM, Rothwell PM. Effects of regular aspirin on long-term cancer incidence and metastasis: a systematic comparison of evidence from observational studies versus randomised trials. Lancet Oncol. 2012 May;13(5):518-27. PMID: 22440112.

 

Bartfai T, Conti B. Fever. ScientificWorldJournal. 2010 Mar 16;10:490-503. PMID: 20305990.

 

Antithrombotic Trialists' (ATT) Collaboration: Baigent C, Blackwell L, Collins R, et al. Aspirin in the primary and secondary prevention of vascular disease: collaborative meta-analysis of individual participant data from randomised trials. Lancet. 2009 May 30;373(9678):1849-60. PMID: 9482214.

 

Tohgi H, Konno S, Tamura K, et al. Effects of low-to-high doses of aspirin on platelet aggregability and metabolites of thromboxane A2 and prostacyclin. Stroke. 1992 Oct;23(10):1400-3. PMID: 1412574.

 

Li W, Li J, Ashok M, et al. A cardiovascular drug rescues mice from lethal sepsis by selectively attentuating a late-acting proinflammatory mediator, high mobility group box 1. J Immunol. 2007 Mar 15;178(6):3856-3864. PMID: 17339485.

" T, Xi "UN number: 2811     Class: 6.1     Packing Group: III

Proper shipping name: Toxic solid, organic, n.o.s. (Acetylsalicylic Acid)"

LKT A0977 Actinomycin 5 mg 95.6 Polypeptide antibiotic produced from Streptomyces; RNA polymerase and topoisomerase inhibitor. Actinomycin D; Meractinomycin; Dactinomycin 50-76-0 ≥98% 1255.5 C62H86N12O16 CC1C(C(=O)NC(C(=O)N2CCCC2C(=O)N(CC(=O)N(C(C(=O)O1)C(C)C)C)C)C(C)C)NC(=O)C3=C4C(=C(C=C3)C)OC5=C(C(=O)C(=C(C5=N4)C(=O)NC6C(OC(=O)C(N(C(=O)CN(C(=O)C7CCCN7C(=O)C(NC6=O)C(C)C)C)C)C(C)C)C)N)C 2 years at 4oC. Ambient Ambient Soluble in ethanol, propylene glycol, water + glycol mixture.  Soluble in  DMSO (50mg/mL) and methanol (10mg/mL). "Merkel O, Wacht N, Sifft E, et al. Actinomycin D induces p53-independent cell death and prolongs survival in high-risk chronic lymphocytic leukemia. Leukemia. 2012 Dec;26(12):2508-16. PMID: 22743622.

 

Koba M, Konopa J. Actinomycin D and its mechanisms of action. Postepy Hig Med Dosw (Online). 2005;59:290-8. PMID: 15995596.

 

Sobell HM. Actinomycin and DNA transcription. Proc Natl Acad Sci U S A. 1985 Aug;82(16):5328-31. PMID: 2410919.

" Repr., T+, Carc. "UN number: 3462     Class:  6.1     Packing group:  II

Proper shipping name:  Toxins, extracted from living sources, solid, n.o.s. (Dactinomycin)

Marine pollutant:  No     Poison inhalation hazard:  No"

LKT A0977 Actinomycin 10 mg 163 Polypeptide antibiotic produced from Streptomyces; RNA polymerase and topoisomerase inhibitor. Actinomycin D; Meractinomycin; Dactinomycin 50-76-0 ≥98% 1255.5 C62H86N12O16 CC1C(C(=O)NC(C(=O)N2CCCC2C(=O)N(CC(=O)N(C(C(=O)O1)C(C)C)C)C)C(C)C)NC(=O)C3=C4C(=C(C=C3)C)OC5=C(C(=O)C(=C(C5=N4)C(=O)NC6C(OC(=O)C(N(C(=O)CN(C(=O)C7CCCN7C(=O)C(NC6=O)C(C)C)C)C)C(C)C)C)N)C 2 years at 4oC. Ambient Ambient Soluble in ethanol, propylene glycol, water + glycol mixture.  Soluble in  DMSO (50mg/mL) and methanol (10mg/mL). "Merkel O, Wacht N, Sifft E, et al. Actinomycin D induces p53-independent cell death and prolongs survival in high-risk chronic lymphocytic leukemia. Leukemia. 2012 Dec;26(12):2508-16. PMID: 22743622.

 

Koba M, Konopa J. Actinomycin D and its mechanisms of action. Postepy Hig Med Dosw (Online). 2005;59:290-8. PMID: 15995596.

 

Sobell HM. Actinomycin and DNA transcription. Proc Natl Acad Sci U S A. 1985 Aug;82(16):5328-31. PMID: 2410919.

" Repr., T+, Carc. "UN number: 3462     Class:  6.1     Packing group:  II

Proper shipping name:  Toxins, extracted from living sources, solid, n.o.s. (Dactinomycin)

Marine pollutant:  No     Poison inhalation hazard:  No"

LKT A2044 Aflatoxin B1 1 mg 46.8 Mycotoxin produced by species of Aspergillus; DNA synthesis inhibitor, carcinogen. (6aR-cis)-2,3,6a,9a-Tetrahydro-4-methoxycyclopenta- [c]furo[3',2':4,5]furo[2,3-h][1]-benzopyran-1,11-dione 1162-65-8 ≥98% 312.27 C17H12O6 COC1=C2C3=C(C(=O)CC3)C(=O)OC2=C4C5C=COC5OC4=C1 Avoid light. Ambient 4°C Soluble in ethanol, methylene chloride. "Miliţă NM, Mihăescu G, Chifiriuc C. Aflatoxins--health risk factors. Bacteriol Virusol Parazitol Epidemiol. 2010 Jan-Mar;55(1):19-24. PMID: 21038701.

 

Gabal MA, Hegazi SA, Hassanin N. Aflatoxin production by Aspergillus flavus field isolates. Vet Hum Toxicol. 1994 Dec;36(6):519-21. PMID: 7900269.

 

Dutton MF, Ehrlich K, Bennett JW. Biosynthetic relationship among aflatoxins B1, B2, M1, and M2. Appl Environ Microbiol. 1985 Jun;49(6):1392-5. PMID: 3925881." T+ "UN Number: 3462     Class: 6.1     Packing Group: 1

Toxins, extracted from living sources, solid, n.o.s. (Aflatoxin B1)

Reportable quantity (RQ):     Marine pollutant:  No     Poison inhalation hazard:  No"

LKT A2044 Aflatoxin B1 5 mg 187.4 Mycotoxin produced by species of Aspergillus; DNA synthesis inhibitor, carcinogen. (6aR-cis)-2,3,6a,9a-Tetrahydro-4-methoxycyclopenta- [c]furo[3',2':4,5]furo[2,3-h][1]-benzopyran-1,11-dione 1162-65-8 ≥98% 312.27 C17H12O6 COC1=C2C3=C(C(=O)CC3)C(=O)OC2=C4C5C=COC5OC4=C1 Avoid light. Ambient 4°C Soluble in ethanol, methylene chloride. "Miliţă NM, Mihăescu G, Chifiriuc C. Aflatoxins--health risk factors. Bacteriol Virusol Parazitol Epidemiol. 2010 Jan-Mar;55(1):19-24. PMID: 21038701.

 

Gabal MA, Hegazi SA, Hassanin N. Aflatoxin production by Aspergillus flavus field isolates. Vet Hum Toxicol. 1994 Dec;36(6):519-21. PMID: 7900269.

 

Dutton MF, Ehrlich K, Bennett JW. Biosynthetic relationship among aflatoxins B1, B2, M1, and M2. Appl Environ Microbiol. 1985 Jun;49(6):1392-5. PMID: 3925881." T+ "UN Number: 3462     Class: 6.1     Packing Group: 1

Toxins, extracted from living sources, solid, n.o.s. (Aflatoxin B1)

Reportable quantity (RQ):     Marine pollutant:  No     Poison inhalation hazard:  No"

LKT A4443 L-(+)-Alliin 25 mg 257.7 Optically active cysteine derivative found in Allium. 3-[(S)-2-Propenylsulfinyl]-L-alanine S-Allyl-L-cysteine sulfoxide; 3-(Allylsulfinyl)alanin; Alliin; EINECS 209-118-9; S-Allyl-L-cysteine-S-oxide 556-27-4 ≥98% 177.22 C6H11NO3S C=CCS(=O)CC(C(=O)O)N Ambient -20°C Soluble in water. Insoluble in ethanol, or acetone.  PBS to 10 mg/mL. "Ieong Tou W, Chang SS, Wu D, et al. Molecular level activation insights from a NR2A/NR2B agonist. J Biomol Struct Dyn. 2014;32(5):683-93. PMID: 23600691.

 

Quintero-Fabián S, Ortuño-Sahagún D, Vázquez-Carrera M, et al. Alliin, a garlic (Allium sativum) compound, prevents LPS-induced inflammation in 3T3-L1 adipocytes. Mediators Inflamm. 2013;2013:381815. PMID: 24453416.

 

Nasim SA, Dhir B, Kapoor R, et al. Alliin obtained from leaf extract of garlic grown under in situ conditions possess higher therapeutic potency as analyzed in alloxan-induced diabetic rats. Pharm Biol. 2011 Apr;49(4):416-21. PMID: 21391887.

 

Sangeetha T, Darlin Quine S. Preventive effect of S-allyl cysteine sulphoxide (Alliin) on mitochondrial dysfunction in normal and isoproterenol induced cardiotoxicity in male Wistar rats: a histopathological study. Mol Cell Biochem. 2009 Aug;328(1-2):1-8. PMID: 19262997.

 

Mousa AS, Mousa SA. Anti-angiogenesis efficacy of the garlic ingredient alliin and antioxidants: role of nitric oxide and p53. Nutr Cancer. 2005;53(1):104-10. PMID: 16351512.

" Xi Not dangerous goods.

LKT A4443 L-(+)-Alliin 50 mg 437.4 Optically active cysteine derivative found in Allium. 3-[(S)-2-Propenylsulfinyl]-L-alanine S-Allyl-L-cysteine sulfoxide; 3-(Allylsulfinyl)alanin; Alliin; EINECS 209-118-9; S-Allyl-L-cysteine-S-oxide 556-27-4 ≥98% 177.22 C6H11NO3S C=CCS(=O)CC(C(=O)O)N Ambient -20°C Soluble in water. Insoluble in ethanol, or acetone.  PBS to 10 mg/mL. "Ieong Tou W, Chang SS, Wu D, et al. Molecular level activation insights from a NR2A/NR2B agonist. J Biomol Struct Dyn. 2014;32(5):683-93. PMID: 23600691.

 

Quintero-Fabián S, Ortuño-Sahagún D, Vázquez-Carrera M, et al. Alliin, a garlic (Allium sativum) compound, prevents LPS-induced inflammation in 3T3-L1 adipocytes. Mediators Inflamm. 2013;2013:381815. PMID: 24453416.

 

Nasim SA, Dhir B, Kapoor R, et al. Alliin obtained from leaf extract of garlic grown under in situ conditions possess higher therapeutic potency as analyzed in alloxan-induced diabetic rats. Pharm Biol. 2011 Apr;49(4):416-21. PMID: 21391887.

 

Sangeetha T, Darlin Quine S. Preventive effect of S-allyl cysteine sulphoxide (Alliin) on mitochondrial dysfunction in normal and isoproterenol induced cardiotoxicity in male Wistar rats: a histopathological study. Mol Cell Biochem. 2009 Aug;328(1-2):1-8. PMID: 19262997.

 

Mousa AS, Mousa SA. Anti-angiogenesis efficacy of the garlic ingredient alliin and antioxidants: role of nitric oxide and p53. Nutr Cancer. 2005;53(1):104-10. PMID: 16351512.

" Xi Not dangerous goods.

LKT A4443 L-(+)-Alliin 100 mg 783 Optically active cysteine derivative found in Allium. 3-[(S)-2-Propenylsulfinyl]-L-alanine S-Allyl-L-cysteine sulfoxide; 3-(Allylsulfinyl)alanin; Alliin; EINECS 209-118-9; S-Allyl-L-cysteine-S-oxide 556-27-4 ≥98% 177.22 C6H11NO3S C=CCS(=O)CC(C(=O)O)N Ambient -20°C Soluble in water. Insoluble in ethanol, or acetone.  PBS to 10 mg/mL. "Ieong Tou W, Chang SS, Wu D, et al. Molecular level activation insights from a NR2A/NR2B agonist. J Biomol Struct Dyn. 2014;32(5):683-93. PMID: 23600691.

 

Quintero-Fabián S, Ortuño-Sahagún D, Vázquez-Carrera M, et al. Alliin, a garlic (Allium sativum) compound, prevents LPS-induced inflammation in 3T3-L1 adipocytes. Mediators Inflamm. 2013;2013:381815. PMID: 24453416.

 

Nasim SA, Dhir B, Kapoor R, et al. Alliin obtained from leaf extract of garlic grown under in situ conditions possess higher therapeutic potency as analyzed in alloxan-induced diabetic rats. Pharm Biol. 2011 Apr;49(4):416-21. PMID: 21391887.

 

Sangeetha T, Darlin Quine S. Preventive effect of S-allyl cysteine sulphoxide (Alliin) on mitochondrial dysfunction in normal and isoproterenol induced cardiotoxicity in male Wistar rats: a histopathological study. Mol Cell Biochem. 2009 Aug;328(1-2):1-8. PMID: 19262997.

 

Mousa AS, Mousa SA. Anti-angiogenesis efficacy of the garlic ingredient alliin and antioxidants: role of nitric oxide and p53. Nutr Cancer. 2005;53(1):104-10. PMID: 16351512.

" Xi Not dangerous goods.

LKT A4445 Allopurinol 5 g 26.4 Purine (hypoxanthine) analog; xanthine oxidase inhibitor. 1,5-Dihydro-4H-pyrazolo[3,4-d]pyrimidin-4-one Adenock; Apurol; Allozym; Apurin; Bloxanth; Embarin; Gichtex; Ketanrift; Lysuron; Urosin; Zyloric 315-30-0 ≥98% 136.11 C5H4N4O C1=C2C(=NC=NC2=O)NN1 Ambient Ambient Soluble in Methanol and DMSO. Slightly soluble in ethanol (0.30 mg/ml) and water (0.48 mg/ml). "Prieto-Moure B, Carabén-Redaño A, Aliena-Valero A, et al. Allopurinol in renal ischemia. J Invest Surg. 2014 Oct;27(5):304-16. PMID: 24914485.

 

Essawy SS, Elbaz AA. Role of adenosine receptors in the anti-nociceptive effects of allopurinol in mice. Eur Rev Med Pharmacol Sci. 2013 Jul;17(14):1857-63. PMID: 23877847.

 

Sakabe M, Fujiki A, Sakamoto T, et al. Xanthine oxidase inhibition prevents atrial fibrillation in a canine model of atrial pacing-induced left ventricular dysfunction. J Cardiovasc Electrophysiol. 2012 Oct;23(10):1130-5. PMID: 22587612.

 

Pacher P, Nivorozhkin A, Szabó C. Therapeutic effects of xanthine oxidase inhibitors: renaissance half a century after the discovery of allopurinol. Pharmacol Rev. 2006 Mar;58(1):87-114. PMID: 16507884.

" T, Xi, Xn "UN number: 2811     Class:  6.1     Packing group:  III

Proper shipping name:  Toxic solid, organic, n.o.s. (Allopurinol)

Marine pollutant:  No     Poison inhalation hazard:  No"

LKT A4445 Allopurinol 10 g 47.8 Purine (hypoxanthine) analog; xanthine oxidase inhibitor. 1,5-Dihydro-4H-pyrazolo[3,4-d]pyrimidin-4-one Adenock; Apurol; Allozym; Apurin; Bloxanth; Embarin; Gichtex; Ketanrift; Lysuron; Urosin; Zyloric 315-30-0 ≥98% 136.11 C5H4N4O C1=C2C(=NC=NC2=O)NN1 Ambient Ambient Soluble in Methanol and DMSO. Slightly soluble in ethanol (0.30 mg/ml) and water (0.48 mg/ml). "Prieto-Moure B, Carabén-Redaño A, Aliena-Valero A, et al. Allopurinol in renal ischemia. J Invest Surg. 2014 Oct;27(5):304-16. PMID: 24914485.

 

Essawy SS, Elbaz AA. Role of adenosine receptors in the anti-nociceptive effects of allopurinol in mice. Eur Rev Med Pharmacol Sci. 2013 Jul;17(14):1857-63. PMID: 23877847.

 

Sakabe M, Fujiki A, Sakamoto T, et al. Xanthine oxidase inhibition prevents atrial fibrillation in a canine model of atrial pacing-induced left ventricular dysfunction. J Cardiovasc Electrophysiol. 2012 Oct;23(10):1130-5. PMID: 22587612.

 

Pacher P, Nivorozhkin A, Szabó C. Therapeutic effects of xanthine oxidase inhibitors: renaissance half a century after the discovery of allopurinol. Pharmacol Rev. 2006 Mar;58(1):87-114. PMID: 16507884.

" T, Xi, Xn "UN number: 2811     Class:  6.1     Packing group:  III

Proper shipping name:  Toxic solid, organic, n.o.s. (Allopurinol)

Marine pollutant:  No     Poison inhalation hazard:  No"

LKT A4544 Allyl Disulfide 500 mg 117.8 Organosulfur found in garlic. Diallyl disulfide 2-Propenyl disulfide; 2-Propenyl disulphide; 4,5-Dithia-1,7-octadiene; AI3-35128; Allyl disulphide; BRN 1699241; CCRIS 6290; Di(2-propenyl) disulfide; Diallyl disulphide; Disulfide, di-2-propenyl 2179-57-9 ≥98% 146.28 C6H10S2 C=CCSSCC=C Ambient -20°C Soluble in ethanol (3 mg/mL) and oil.  Insoluble in water. DMSO to 5 mg/mL. DMF to 10 mg/mL. Chloroform, methanol. "Schelkle B, Snellgrove D, Cable J. In vitro and in vivo efficacy of garlic compounds against Gyrodactylus turnbulli infecting the guppy (Poecilia reticulata). Vet Parasitol. 2013 Nov 15;198(1-2):96-101. PMID: 24074607.

 

Dasgupta P, Bandyopadhyay SS. Role of di-allyl disulfide, a garlic component in NF-κB mediated transient G2-M phase arrest and apoptosis in human leukemic cell-lines. Nutr Cancer. 2013;65(4):611-22. PMID: 23659453.

 

Trinh K, Moore K, Wes PD, et al. Induction of the phase II detoxification pathway suppresses neuron loss in Drosophila models of Parkinson's disease. J Neurosci. 2008 Jan 9;28(2):465-72. PMID: 18184789.

 

Chung LY. The antioxidant properties of garlic compounds: allyl cysteine, alliin, allicin, and allyl disulfide. J Med Food. 2006 Summer;9(2):205-13. PMID: 16822206.

 

Singh DK, Porter TD. Inhibition of sterol 4alpha-methyl oxidase is the principal mechanism by which garlic decreases cholesterol synthesis. J Nutr. 2006 Mar;136(3 Suppl):759S-764S. PMID: 16484558.

 

Shoji S, Furuishi K, Yanase R, et al. Allyl compounds selectively killed human immunodeficiency virus (type 1)-infected cells. Biochem Biophys Res Commun. 1993 Jul 30;194(2):610-21. PMID: 8343148.

" Xn, Xi "UN number: 1992  Class:  3  Packing group:  III

Proper shipping name:  Flammable liquid, Toxic, n.o.s. (Diallyl disulfide)

Reportable quantity (RQ):  Marine pollutant:  No;  Poison inhalation hazard:  No"

LKT A4544 Allyl Disulfide 1 g 222.9 Organosulfur found in garlic. Diallyl disulfide 2-Propenyl disulfide; 2-Propenyl disulphide; 4,5-Dithia-1,7-octadiene; AI3-35128; Allyl disulphide; BRN 1699241; CCRIS 6290; Di(2-propenyl) disulfide; Diallyl disulphide; Disulfide, di-2-propenyl 2179-57-9 ≥98% 146.28 C6H10S2 C=CCSSCC=C Ambient -20°C Soluble in ethanol (3 mg/mL) and oil.  Insoluble in water. DMSO to 5 mg/mL. DMF to 10 mg/mL. Chloroform, methanol. "Schelkle B, Snellgrove D, Cable J. In vitro and in vivo efficacy of garlic compounds against Gyrodactylus turnbulli infecting the guppy (Poecilia reticulata). Vet Parasitol. 2013 Nov 15;198(1-2):96-101. PMID: 24074607.

 

Dasgupta P, Bandyopadhyay SS. Role of di-allyl disulfide, a garlic component in NF-κB mediated transient G2-M phase arrest and apoptosis in human leukemic cell-lines. Nutr Cancer. 2013;65(4):611-22. PMID: 23659453.

 

Trinh K, Moore K, Wes PD, et al. Induction of the phase II detoxification pathway suppresses neuron loss in Drosophila models of Parkinson's disease. J Neurosci. 2008 Jan 9;28(2):465-72. PMID: 18184789.

 

Chung LY. The antioxidant properties of garlic compounds: allyl cysteine, alliin, allicin, and allyl disulfide. J Med Food. 2006 Summer;9(2):205-13. PMID: 16822206.

 

Singh DK, Porter TD. Inhibition of sterol 4alpha-methyl oxidase is the principal mechanism by which garlic decreases cholesterol synthesis. J Nutr. 2006 Mar;136(3 Suppl):759S-764S. PMID: 16484558.

 

Shoji S, Furuishi K, Yanase R, et al. Allyl compounds selectively killed human immunodeficiency virus (type 1)-infected cells. Biochem Biophys Res Commun. 1993 Jul 30;194(2):610-21. PMID: 8343148.

" Xn, Xi "UN number: 1992  Class:  3  Packing group:  III

Proper shipping name:  Flammable liquid, Toxic, n.o.s. (Diallyl disulfide)

Reportable quantity (RQ):  Marine pollutant:  No;  Poison inhalation hazard:  No"

LKT A4544 Allyl Disulfide 5 g 837.2 Organosulfur found in garlic. Diallyl disulfide 2-Propenyl disulfide; 2-Propenyl disulphide; 4,5-Dithia-1,7-octadiene; AI3-35128; Allyl disulphide; BRN 1699241; CCRIS 6290; Di(2-propenyl) disulfide; Diallyl disulphide; Disulfide, di-2-propenyl 2179-57-9 ≥98% 146.28 C6H10S2 C=CCSSCC=C Ambient -20°C Soluble in ethanol (3 mg/mL) and oil.  Insoluble in water. DMSO to 5 mg/mL. DMF to 10 mg/mL. Chloroform, methanol. "Schelkle B, Snellgrove D, Cable J. In vitro and in vivo efficacy of garlic compounds against Gyrodactylus turnbulli infecting the guppy (Poecilia reticulata). Vet Parasitol. 2013 Nov 15;198(1-2):96-101. PMID: 24074607.

 

Dasgupta P, Bandyopadhyay SS. Role of di-allyl disulfide, a garlic component in NF-κB mediated transient G2-M phase arrest and apoptosis in human leukemic cell-lines. Nutr Cancer. 2013;65(4):611-22. PMID: 23659453.

 

Trinh K, Moore K, Wes PD, et al. Induction of the phase II detoxification pathway suppresses neuron loss in Drosophila models of Parkinson's disease. J Neurosci. 2008 Jan 9;28(2):465-72. PMID: 18184789.

 

Chung LY. The antioxidant properties of garlic compounds: allyl cysteine, alliin, allicin, and allyl disulfide. J Med Food. 2006 Summer;9(2):205-13. PMID: 16822206.

 

Singh DK, Porter TD. Inhibition of sterol 4alpha-methyl oxidase is the principal mechanism by which garlic decreases cholesterol synthesis. J Nutr. 2006 Mar;136(3 Suppl):759S-764S. PMID: 16484558.

 

Shoji S, Furuishi K, Yanase R, et al. Allyl compounds selectively killed human immunodeficiency virus (type 1)-infected cells. Biochem Biophys Res Commun. 1993 Jul 30;194(2):610-21. PMID: 8343148.

" Xn, Xi "UN number: 1992  Class:  3  Packing group:  III

Proper shipping name:  Flammable liquid, Toxic, n.o.s. (Diallyl disulfide)

Reportable quantity (RQ):  Marine pollutant:  No;  Poison inhalation hazard:  No"

LKT A4496 Alyssin 25 mg 155.4 Naturally sourced ITC, sulfonyl analog of sulforaphane. 1-Isothiocyanato-5-(methylsulfinyl)pentane; 5-methylsulfinylpentyl isothiocyanate 646-23-1 ≥97% 191.32 C7H13NOS2 CS(=O)CCCCCN=C=S >3 yrs. at -20°C Ambient -20°C Soluble in water, DMSO, ethanol,  or chloroform. "Lubelska K, Misiewicz-Krzemińska I, Milczarek M, et al. Isothiocyanate-drug interactions in the human adenocarcinoma cell line Caco-2. Mol Cell Biochem. 2012 Aug;367(1-2):19-29. PMID: 22527941.

 

Kim MJ, Kim SH, Lim SJ. Comparison of the apoptosis-inducing capability of sulforaphane analogues in human colon cancer cells. Anticancer Res. 2010 Sep;30(9):3611-9. PMID: 20944144.

 

Skupinska K, Misiewicz-Krzeminska I, Stypulkowski R, et al. Sulforaphane and its analogues inhibit CYP1A1 and CYP1A2 activity induced by benzo[a]pyrene. J Biochem Mol Toxicol. 2009 Jan-Feb;23(1):18-28. PMID: 19202560.

" Not dangerous goods.

LKT A4496 Alyssin 50 mg 278.3 Naturally sourced ITC, sulfonyl analog of sulforaphane. 1-Isothiocyanato-5-(methylsulfinyl)pentane; 5-methylsulfinylpentyl isothiocyanate 646-23-1 ≥97% 191.32 C7H13NOS2 CS(=O)CCCCCN=C=S >3 yrs. at -20°C Ambient -20°C Soluble in water, DMSO, ethanol,  or chloroform. "Lubelska K, Misiewicz-Krzemińska I, Milczarek M, et al. Isothiocyanate-drug interactions in the human adenocarcinoma cell line Caco-2. Mol Cell Biochem. 2012 Aug;367(1-2):19-29. PMID: 22527941.

 

Kim MJ, Kim SH, Lim SJ. Comparison of the apoptosis-inducing capability of sulforaphane analogues in human colon cancer cells. Anticancer Res. 2010 Sep;30(9):3611-9. PMID: 20944144.

 

Skupinska K, Misiewicz-Krzeminska I, Stypulkowski R, et al. Sulforaphane and its analogues inhibit CYP1A1 and CYP1A2 activity induced by benzo[a]pyrene. J Biochem Mol Toxicol. 2009 Jan-Feb;23(1):18-28. PMID: 19202560.

" Not dangerous goods.

LKT A4496 Alyssin 100 mg 493.5 Naturally sourced ITC, sulfonyl analog of sulforaphane. 1-Isothiocyanato-5-(methylsulfinyl)pentane; 5-methylsulfinylpentyl isothiocyanate 646-23-1 ≥97% 191.32 C7H13NOS2 CS(=O)CCCCCN=C=S >3 yrs. at -20°C Ambient -20°C Soluble in water, DMSO, ethanol,  or chloroform. "Lubelska K, Misiewicz-Krzemińska I, Milczarek M, et al. Isothiocyanate-drug interactions in the human adenocarcinoma cell line Caco-2. Mol Cell Biochem. 2012 Aug;367(1-2):19-29. PMID: 22527941.

 

Kim MJ, Kim SH, Lim SJ. Comparison of the apoptosis-inducing capability of sulforaphane analogues in human colon cancer cells. Anticancer Res. 2010 Sep;30(9):3611-9. PMID: 20944144.

 

Skupinska K, Misiewicz-Krzeminska I, Stypulkowski R, et al. Sulforaphane and its analogues inhibit CYP1A1 and CYP1A2 activity induced by benzo[a]pyrene. J Biochem Mol Toxicol. 2009 Jan-Feb;23(1):18-28. PMID: 19202560.

" Not dangerous goods.

LKT A4496 Alyssin 500 mg 1575 Naturally sourced ITC, sulfonyl analog of sulforaphane. 1-Isothiocyanato-5-(methylsulfinyl)pentane; 5-methylsulfinylpentyl isothiocyanate 646-23-1 ≥97% 191.32 C7H13NOS2 CS(=O)CCCCCN=C=S >3 yrs. at -20°C Ambient -20°C Soluble in water, DMSO, ethanol,  or chloroform. "Lubelska K, Misiewicz-Krzemińska I, Milczarek M, et al. Isothiocyanate-drug interactions in the human adenocarcinoma cell line Caco-2. Mol Cell Biochem. 2012 Aug;367(1-2):19-29. PMID: 22527941.

 

Kim MJ, Kim SH, Lim SJ. Comparison of the apoptosis-inducing capability of sulforaphane analogues in human colon cancer cells. Anticancer Res. 2010 Sep;30(9):3611-9. PMID: 20944144.

 

Skupinska K, Misiewicz-Krzeminska I, Stypulkowski R, et al. Sulforaphane and its analogues inhibit CYP1A1 and CYP1A2 activity induced by benzo[a]pyrene. J Biochem Mol Toxicol. 2009 Jan-Feb;23(1):18-28. PMID: 19202560.

" Not dangerous goods.

LKT A4497 Alyssin Sulfone 25 mg 155.4 Naturally sourced ITC, sulfonyl analog of sulforaphane. ≥97% 207.31 C7H13NO2S2 CS(=O)CCCCCN=C=S >3 yrs. at -20°C Ambient -20°C Soluble in DMSO, ethanol, or chloroform. "Lubelska K, Misiewicz-Krzemińska I, Milczarek M, et al. Isothiocyanate-drug interactions in the human adenocarcinoma cell line Caco-2. Mol Cell Biochem. 2012 Aug;367(1-2):19-29. PMID: 22527941.

 

Kim MJ, Kim SH, Lim SJ. Comparison of the apoptosis-inducing capability of sulforaphane analogues in human colon cancer cells. Anticancer Res. 2010 Sep;30(9):3611-9. PMID: 20944144.

" Not dangerous goods.

LKT A4497 Alyssin Sulfone 50 mg 260.4 Naturally sourced ITC, sulfonyl analog of sulforaphane. ≥97% 207.31 C7H13NO2S2 CS(=O)CCCCCN=C=S >3 yrs. at -20°C Ambient -20°C Soluble in DMSO, ethanol, or chloroform. "Lubelska K, Misiewicz-Krzemińska I, Milczarek M, et al. Isothiocyanate-drug interactions in the human adenocarcinoma cell line Caco-2. Mol Cell Biochem. 2012 Aug;367(1-2):19-29. PMID: 22527941.

 

Kim MJ, Kim SH, Lim SJ. Comparison of the apoptosis-inducing capability of sulforaphane analogues in human colon cancer cells. Anticancer Res. 2010 Sep;30(9):3611-9. PMID: 20944144.

" Not dangerous goods.

LKT A4497 Alyssin Sulfone 100 mg 456.8 Naturally sourced ITC, sulfonyl analog of sulforaphane. ≥97% 207.31 C7H13NO2S2 CS(=O)CCCCCN=C=S >3 yrs. at -20°C Ambient -20°C Soluble in DMSO, ethanol, or chloroform. "Lubelska K, Misiewicz-Krzemińska I, Milczarek M, et al. Isothiocyanate-drug interactions in the human adenocarcinoma cell line Caco-2. Mol Cell Biochem. 2012 Aug;367(1-2):19-29. PMID: 22527941.

 

Kim MJ, Kim SH, Lim SJ. Comparison of the apoptosis-inducing capability of sulforaphane analogues in human colon cancer cells. Anticancer Res. 2010 Sep;30(9):3611-9. PMID: 20944144.

" Not dangerous goods.

LKT A4497 Alyssin Sulfone 500 mg 1575 Naturally sourced ITC, sulfonyl analog of sulforaphane. ≥97% 207.31 C7H13NO2S2 CS(=O)CCCCCN=C=S >3 yrs. at -20°C Ambient -20°C Soluble in DMSO, ethanol, or chloroform. "Lubelska K, Misiewicz-Krzemińska I, Milczarek M, et al. Isothiocyanate-drug interactions in the human adenocarcinoma cell line Caco-2. Mol Cell Biochem. 2012 Aug;367(1-2):19-29. PMID: 22527941.

 

Kim MJ, Kim SH, Lim SJ. Comparison of the apoptosis-inducing capability of sulforaphane analogues in human colon cancer cells. Anticancer Res. 2010 Sep;30(9):3611-9. PMID: 20944144.

" Not dangerous goods.

LKT A5030 4-Aminophenylphosphate Monosodium 10 mg 75.8 Alkaline phosphatase substrate used to quantify enzyme activity. 4-aminobenzenephosphoric sodium 52331-30-3 ≥97% 211.09 C6H7NO4PNa C1=CC(=CC=C1N)P(=O)([O-])[O-] Ambient -20°C Soluble in methanol and water. "Akanda MR, Tamilavan V, Park S, et al. Hydroquinone diphosphate as a phosphatase substrate in enzymatic amplification combined with electrochemical-chemical-chemical redox cycling for the detection of E. coli O157:H7. Anal Chem. 2013 Feb 5;85(3):1631-6. PMID: 23327094.

 

Pemberton RM, Hart JP, Stoddard P, et al. A comparison of 1-naphthyl phosphate and 4 aminophenyl phosphate as enzyme substrates for use with a screen-printed amperometric immunosensor for progesterone in cows' milk. Biosens Bioelectron. 1999 May 31;14(5):495-503. PMID: 10451917.

 

Xiang Y, Zhang Y, Qian X, et al. Ultrasensitive aptamer-based protein detection via a dual amplified biocatalytic strategy. Biosens Bioelectron. 2010 Jul 15;25(11):2539-2542. PMID: 20452761.

" Not dangerous goods.

LKT A5030 4-Aminophenylphosphate Monosodium 50 mg 261.5 Alkaline phosphatase substrate used to quantify enzyme activity. 4-aminobenzenephosphoric sodium 52331-30-3 ≥97% 211.09 C6H7NO4PNa C1=CC(=CC=C1N)P(=O)([O-])[O-] Ambient -20°C Soluble in methanol and water. "Akanda MR, Tamilavan V, Park S, et al. Hydroquinone diphosphate as a phosphatase substrate in enzymatic amplification combined with electrochemical-chemical-chemical redox cycling for the detection of E. coli O157:H7. Anal Chem. 2013 Feb 5;85(3):1631-6. PMID: 23327094.

 

Pemberton RM, Hart JP, Stoddard P, et al. A comparison of 1-naphthyl phosphate and 4 aminophenyl phosphate as enzyme substrates for use with a screen-printed amperometric immunosensor for progesterone in cows' milk. Biosens Bioelectron. 1999 May 31;14(5):495-503. PMID: 10451917.

 

Xiang Y, Zhang Y, Qian X, et al. Ultrasensitive aptamer-based protein detection via a dual amplified biocatalytic strategy. Biosens Bioelectron. 2010 Jul 15;25(11):2539-2542. PMID: 20452761.

" Not dangerous goods.

LKT A5030 4-Aminophenylphosphate Monosodium 100 mg 479.3 Alkaline phosphatase substrate used to quantify enzyme activity. 4-aminobenzenephosphoric sodium 52331-30-3 ≥97% 211.09 C6H7NO4PNa C1=CC(=CC=C1N)P(=O)([O-])[O-] Ambient -20°C Soluble in methanol and water. "Akanda MR, Tamilavan V, Park S, et al. Hydroquinone diphosphate as a phosphatase substrate in enzymatic amplification combined with electrochemical-chemical-chemical redox cycling for the detection of E. coli O157:H7. Anal Chem. 2013 Feb 5;85(3):1631-6. PMID: 23327094.

 

Pemberton RM, Hart JP, Stoddard P, et al. A comparison of 1-naphthyl phosphate and 4 aminophenyl phosphate as enzyme substrates for use with a screen-printed amperometric immunosensor for progesterone in cows' milk. Biosens Bioelectron. 1999 May 31;14(5):495-503. PMID: 10451917.

 

Xiang Y, Zhang Y, Qian X, et al. Ultrasensitive aptamer-based protein detection via a dual amplified biocatalytic strategy. Biosens Bioelectron. 2010 Jul 15;25(11):2539-2542. PMID: 20452761.

" Not dangerous goods.

LKT A5217 trans-Anethole 50 ml 88.1 Phenylpropene derivative found in essential oils; NMDA agonist. 1-Methoxy-4-(1E)-1-propenylbenzene trans-p-Propenylanisole; Anise camphor; Isoestragole; Monasirup 4180-23-8 ≥98% 148.2 C10H12O CC=CC1=CC=C(C=C1)OC Ambient Ambient Soluble in benzene, ethyl acetate, acetone, carbon disulfide, or petr ether.  Ethanol (500 mg/mL). "Miyagawa M, Satou T, Yukimune C, et al. Anxiolytic-Like Effect of Illicium verum Fruit Oil, trans-Anethole and Related Compounds in Mice. Phytother Res. 2014 Jun 11. [Epub ahead of print]. PMID: 24919985.

 

Ryu S, Seol GH, Park H, et al. Trans-anethole protects cortical neuronal cells against oxygen-glucose deprivation/reoxygenation. Neurol Sci. 2014 Oct;35(10):1541-7. PMID: 24777545.

 

Fujita KI, Tatsumi M, Ogita A, et al. Anethole induces apoptotic cell death accompanied by reactive oxygen species production and DNA fragmentation in Aspergillus fumigatus and Saccharomyces cerevisiae. FEBS J. 2014 Jan 2. [Epub ahead of print]. PMID: 24393541.

 

Cho HI, Kim KM, Kwak JH, et al. Protective mechanism of anethole on hepatic ischemia/reperfusion injury in mice. J Nat Prod. 2013 Sep 27;76(9):1717-23. PMID: 23962021.

" Xi Not dangerous goods.

LKT A5217 trans-Anethole 100 ml 152 Phenylpropene derivative found in essential oils; NMDA agonist. 1-Methoxy-4-(1E)-1-propenylbenzene trans-p-Propenylanisole; Anise camphor; Isoestragole; Monasirup 4180-23-8 ≥98% 148.2 C10H12O CC=CC1=CC=C(C=C1)OC Ambient Ambient Soluble in benzene, ethyl acetate, acetone, carbon disulfide, or petr ether.  Ethanol (500 mg/mL). "Miyagawa M, Satou T, Yukimune C, et al. Anxiolytic-Like Effect of Illicium verum Fruit Oil, trans-Anethole and Related Compounds in Mice. Phytother Res. 2014 Jun 11. [Epub ahead of print]. PMID: 24919985.

 

Ryu S, Seol GH, Park H, et al. Trans-anethole protects cortical neuronal cells against oxygen-glucose deprivation/reoxygenation. Neurol Sci. 2014 Oct;35(10):1541-7. PMID: 24777545.

 

Fujita KI, Tatsumi M, Ogita A, et al. Anethole induces apoptotic cell death accompanied by reactive oxygen species production and DNA fragmentation in Aspergillus fumigatus and Saccharomyces cerevisiae. FEBS J. 2014 Jan 2. [Epub ahead of print]. PMID: 24393541.

 

Cho HI, Kim KM, Kwak JH, et al. Protective mechanism of anethole on hepatic ischemia/reperfusion injury in mice. J Nat Prod. 2013 Sep 27;76(9):1717-23. PMID: 23962021.

" Xi Not dangerous goods.

LKT A1865 Aeroplysinin 100 µg 40.4 Marine sponge alkaloid. 3,5-dibromo-1,5-dihydroxy-4-methoxy-2,4-cyclo- hexadiene-1-acetonitrile "(1S-trans)-3,5-Dibromo-1,6-dihydroxy-4-methoxy-2,4-cyclohexadiene-1-

acetonitrile" 28656-91-9 ≥96% 338.98 C9H9Br2NO3 COC1=C(C(C(C=C1Br)(CC#N)O)O)Br Ambient -20°C Soluble in DMSO or ethanol. "Martínez-Poveda B, García-Vilas JA, Cárdenas C, et al. The brominated compound aeroplysinin-1 inhibits proliferation and the expression of key pro- inflammatory molecules in human endothelial and monocyte cells. PLoS One. 2013;8(1):e55203. PMID: 23383109.

 

Rodríguez-Nieto S, González-Iriarte M, Carmona R, et al. Antiangiogenic activity of aeroplysinin-1, a brominated compound isolated from a marine sponge. FASEB J. 2002 Feb;16(2):261-3. PMID: 11772945.

 

Koulman A, Proksch P, Ebel R, et al. Cytotoxicity and mode of action of aeroplysinin-1 and a related dienonefrom the sponge Aplysina aerophoba. J Nat Prod. 1996 Jun;59(6):591-4. PMID: 8786366.

" Not dangerous goods.

LKT A1865 Aeroplysinin 5 x 100 µg 138.7 Marine sponge alkaloid. 3,5-dibromo-1,5-dihydroxy-4-methoxy-2,4-cyclo- hexadiene-1-acetonitrile "(1S-trans)-3,5-Dibromo-1,6-dihydroxy-4-methoxy-2,4-cyclohexadiene-1-

acetonitrile" 28656-91-9 ≥96% 338.98 C9H9Br2NO3 COC1=C(C(C(C=C1Br)(CC#N)O)O)Br Ambient -20°C Soluble in DMSO or ethanol. "Martínez-Poveda B, García-Vilas JA, Cárdenas C, et al. The brominated compound aeroplysinin-1 inhibits proliferation and the expression of key pro- inflammatory molecules in human endothelial and monocyte cells. PLoS One. 2013;8(1):e55203. PMID: 23383109.

 

Rodríguez-Nieto S, González-Iriarte M, Carmona R, et al. Antiangiogenic activity of aeroplysinin-1, a brominated compound isolated from a marine sponge. FASEB J. 2002 Feb;16(2):261-3. PMID: 11772945.

 

Koulman A, Proksch P, Ebel R, et al. Cytotoxicity and mode of action of aeroplysinin-1 and a related dienonefrom the sponge Aplysina aerophoba. J Nat Prod. 1996 Jun;59(6):591-4. PMID: 8786366.

" Not dangerous goods.

LKT A1865 Aeroplysinin 1 mg 231.1 Marine sponge alkaloid. 3,5-dibromo-1,5-dihydroxy-4-methoxy-2,4-cyclo- hexadiene-1-acetonitrile "(1S-trans)-3,5-Dibromo-1,6-dihydroxy-4-methoxy-2,4-cyclohexadiene-1-

acetonitrile" 28656-91-9 ≥96% 338.98 C9H9Br2NO3 COC1=C(C(C(C=C1Br)(CC#N)O)O)Br Ambient -20°C Soluble in DMSO or ethanol. "Martínez-Poveda B, García-Vilas JA, Cárdenas C, et al. The brominated compound aeroplysinin-1 inhibits proliferation and the expression of key pro- inflammatory molecules in human endothelial and monocyte cells. PLoS One. 2013;8(1):e55203. PMID: 23383109.

 

Rodríguez-Nieto S, González-Iriarte M, Carmona R, et al. Antiangiogenic activity of aeroplysinin-1, a brominated compound isolated from a marine sponge. FASEB J. 2002 Feb;16(2):261-3. PMID: 11772945.

 

Koulman A, Proksch P, Ebel R, et al. Cytotoxicity and mode of action of aeroplysinin-1 and a related dienonefrom the sponge Aplysina aerophoba. J Nat Prod. 1996 Jun;59(6):591-4. PMID: 8786366.

" Not dangerous goods.

LKT A6978 Artemisinin 100 mg 47.6 Sesquiterpene lactone found in Artemisia (wormwood). (3R,5aS,6R,8aS,9R,12S,12aR)-Octahydro-3,6,9-tri- methyl-3,12-epoxy-12H-pyrano[4,3-j]-1,2-benzo- dioxepin-10(3H)-one Artemisine; Arteannuin; Quinghaosu; QHS 63968-64-9 ≥98% 282.35 C15H22O5 CC1CCC2C(C(=O)OC3C24C1CCC(O3)(OO4)C)C Ambient Ambient Insoluble in water. Soluble in DMSO, acetone, ethanol, or chloroform "Gu Y, Wu G, Wang X, et al. Artemisinin prevents electric remodeling following myocardial infarction possibly by upregulating the expression of connexin 43. Mol Med Rep. 2014 Oct;10(4):1851-6. PMID: 25110145.

 

Tan WQ, Chen G, Jia B, et al. Artemisinin inhibits neuroblastoma proliferation through activation of AHP-activated protein kinase (AMPK) signaling. Pharmazie. 2014 Jun;69(6):468-72. PMID: 24974584.

 

Patel K, Batty KT, Moore BR, et al. Predicting the parasite killing effect of artemisinin combination therapy in a murine malaria model. J Antimicrob Chemother. 2014 Aug;69(8):2155-63. PMID: 24777899.

 

Yu WY, Kan WJ, Yu PX, et al. Anti-inflammatory effect and mechanism of artemisinin and dihydroartemisinin. Zhongguo Zhong Yao Za Zhi. 2012 Sep;37(17):2618-21. PMID: 23236763." None Not dangerous goods.

LKT A6978 Artemisinin 500 mg 163 Sesquiterpene lactone found in Artemisia (wormwood). (3R,5aS,6R,8aS,9R,12S,12aR)-Octahydro-3,6,9-tri- methyl-3,12-epoxy-12H-pyrano[4,3-j]-1,2-benzo- dioxepin-10(3H)-one Artemisine; Arteannuin; Quinghaosu; QHS 63968-64-9 ≥98% 282.35 C15H22O5 CC1CCC2C(C(=O)OC3C24C1CCC(O3)(OO4)C)C Ambient Ambient Insoluble in water. Soluble in DMSO, acetone, ethanol, or chloroform "Gu Y, Wu G, Wang X, et al. Artemisinin prevents electric remodeling following myocardial infarction possibly by upregulating the expression of connexin 43. Mol Med Rep. 2014 Oct;10(4):1851-6. PMID: 25110145.

 

Tan WQ, Chen G, Jia B, et al. Artemisinin inhibits neuroblastoma proliferation through activation of AHP-activated protein kinase (AMPK) signaling. Pharmazie. 2014 Jun;69(6):468-72. PMID: 24974584.

 

Patel K, Batty KT, Moore BR, et al. Predicting the parasite killing effect of artemisinin combination therapy in a murine malaria model. J Antimicrob Chemother. 2014 Aug;69(8):2155-63. PMID: 24777899.

 

Yu WY, Kan WJ, Yu PX, et al. Anti-inflammatory effect and mechanism of artemisinin and dihydroartemisinin. Zhongguo Zhong Yao Za Zhi. 2012 Sep;37(17):2618-21. PMID: 23236763." None Not dangerous goods.

LKT A6978 Artemisinin 1 g 247.2 Sesquiterpene lactone found in Artemisia (wormwood). (3R,5aS,6R,8aS,9R,12S,12aR)-Octahydro-3,6,9-tri- methyl-3,12-epoxy-12H-pyrano[4,3-j]-1,2-benzo- dioxepin-10(3H)-one Artemisine; Arteannuin; Quinghaosu; QHS 63968-64-9 ≥98% 282.35 C15H22O5 CC1CCC2C(C(=O)OC3C24C1CCC(O3)(OO4)C)C Ambient Ambient Insoluble in water. Soluble in DMSO, acetone, ethanol, or chloroform "Gu Y, Wu G, Wang X, et al. Artemisinin prevents electric remodeling following myocardial infarction possibly by upregulating the expression of connexin 43. Mol Med Rep. 2014 Oct;10(4):1851-6. PMID: 25110145.

 

Tan WQ, Chen G, Jia B, et al. Artemisinin inhibits neuroblastoma proliferation through activation of AHP-activated protein kinase (AMPK) signaling. Pharmazie. 2014 Jun;69(6):468-72. PMID: 24974584.

 

Patel K, Batty KT, Moore BR, et al. Predicting the parasite killing effect of artemisinin combination therapy in a murine malaria model. J Antimicrob Chemother. 2014 Aug;69(8):2155-63. PMID: 24777899.

 

Yu WY, Kan WJ, Yu PX, et al. Anti-inflammatory effect and mechanism of artemisinin and dihydroartemisinin. Zhongguo Zhong Yao Za Zhi. 2012 Sep;37(17):2618-21. PMID: 23236763." None Not dangerous goods.

LKT A7309 Ascorbyl Palmitate 25 g 51 Fat-soluble vitamin C derivative. L-Ascorbic acid, 6-palmitate Ascorbic acid palmitate; Ascorbic palmitate; Quicifal; Ondascora; Vitamin C palmitate; 6-Palmitoylascorbic acid 137-66-6 ≥95% 414.53 C22H38O7 CCCCCCCCCCCCCCCC(=O)OCC(C1C(=C(C(=O)O1)O)O)O Ambient Ambient Insoluble in water.  Ethanol (8 mg/mL) "Zariwala MG, Farnaud S, Merchant Z, et al. Ascorbyl palmitate/DSPE-PEG nanocarriers for oral iron delivery: preparation, characterisation and in vitro evaluation. Colloids Surf B Biointerfaces. 2014 Mar 1;115:86-92. PMID: 24333557.

 

Let MB, Jacobsen C, Meyer AS. Ascorbyl palmitate, gamma-tocopherol, and EDTA affect lipid oxidation in fish oil enriched salad dressing differently. J Agric Food Chem. 2007 Mar 21;55(6):2369-75. PMID: 17319681.

 

Llabot JM, Palma SD, Manzo RH, et al. Design of novel antifungal mucoadhesive films. Part II. Formulation and in vitro biopharmaceutical evaluation. Int J Pharm. 2007 May 24;336(2):263-8. PMID: 17223291.

 

Jurkovic P, Sentjurc M, Gasperlin M, et al. Skin protection against ultraviolet induced free radicals with ascorbyl palmitate in microemulsions. Eur J Pharm Biopharm. 2003 Jul;56(1):59-66. PMID: 12837482.

" None Not dangerous goods.

LKT A7309 Ascorbyl Palmitate 100 g 138.8 Fat-soluble vitamin C derivative. L-Ascorbic acid, 6-palmitate Ascorbic acid palmitate; Ascorbic palmitate; Quicifal; Ondascora; Vitamin C palmitate; 6-Palmitoylascorbic acid 137-66-6 ≥95% 414.53 C22H38O7 CCCCCCCCCCCCCCCC(=O)OCC(C1C(=C(C(=O)O1)O)O)O Ambient Ambient Insoluble in water.  Ethanol (8 mg/mL) "Zariwala MG, Farnaud S, Merchant Z, et al. Ascorbyl palmitate/DSPE-PEG nanocarriers for oral iron delivery: preparation, characterisation and in vitro evaluation. Colloids Surf B Biointerfaces. 2014 Mar 1;115:86-92. PMID: 24333557.

 

Let MB, Jacobsen C, Meyer AS. Ascorbyl palmitate, gamma-tocopherol, and EDTA affect lipid oxidation in fish oil enriched salad dressing differently. J Agric Food Chem. 2007 Mar 21;55(6):2369-75. PMID: 17319681.

 

Llabot JM, Palma SD, Manzo RH, et al. Design of novel antifungal mucoadhesive films. Part II. Formulation and in vitro biopharmaceutical evaluation. Int J Pharm. 2007 May 24;336(2):263-8. PMID: 17223291.

 

Jurkovic P, Sentjurc M, Gasperlin M, et al. Skin protection against ultraviolet induced free radicals with ascorbyl palmitate in microemulsions. Eur J Pharm Biopharm. 2003 Jul;56(1):59-66. PMID: 12837482.

" None Not dangerous goods.

LKT A7309 Ascorbyl Palmitate 500 g 370.3 Fat-soluble vitamin C derivative. L-Ascorbic acid, 6-palmitate Ascorbic acid palmitate; Ascorbic palmitate; Quicifal; Ondascora; Vitamin C palmitate; 6-Palmitoylascorbic acid 137-66-6 ≥95% 414.53 C22H38O7 CCCCCCCCCCCCCCCC(=O)OCC(C1C(=C(C(=O)O1)O)O)O Ambient Ambient Insoluble in water.  Ethanol (8 mg/mL) "Zariwala MG, Farnaud S, Merchant Z, et al. Ascorbyl palmitate/DSPE-PEG nanocarriers for oral iron delivery: preparation, characterisation and in vitro evaluation. Colloids Surf B Biointerfaces. 2014 Mar 1;115:86-92. PMID: 24333557.

 

Let MB, Jacobsen C, Meyer AS. Ascorbyl palmitate, gamma-tocopherol, and EDTA affect lipid oxidation in fish oil enriched salad dressing differently. J Agric Food Chem. 2007 Mar 21;55(6):2369-75. PMID: 17319681.

 

Llabot JM, Palma SD, Manzo RH, et al. Design of novel antifungal mucoadhesive films. Part II. Formulation and in vitro biopharmaceutical evaluation. Int J Pharm. 2007 May 24;336(2):263-8. PMID: 17223291.

 

Jurkovic P, Sentjurc M, Gasperlin M, et al. Skin protection against ultraviolet induced free radicals with ascorbyl palmitate in microemulsions. Eur J Pharm Biopharm. 2003 Jul;56(1):59-66. PMID: 12837482.

" None Not dangerous goods.

LKT B1652 Benzo[a]pyrene 500 mg 156.2 Polycyclic aromatic hydrocarbon (PAH) found in coal tar, cigarette smoke, and wood smoke; carcinogen. 3,4-Benzpyrene 1,2-benzpyrene; 1,2-benzopyrene, 6,7-benzopyrene; benzo[a]pyrene; BP; 3,4-benzylpyrene; 3,4-benz[a]pyrene 50-32-8 ≥98% 252.32 C20H12 C1=CC=C2C3=C4C(=CC2=C1)C=CC5=C4C(=CC=C5)C=C3 Ambient Ambient Soluble in chloroform, benzene, toluene, xylene and ether.  Insoluble in water. "Gao L, Mai A, Li X, et al. LncRNA-DQ786227-mediated cell malignant transformation induced by benzo(a)pyrene. Toxicol Lett. 2013 Nov 25;223(2):205-10. PMID: 24084393.

 

Naveenkumar C, Raghunandakumar S, Asokkumar S, et al. Mitigating role of baicalein on lysosomal enzymes and xenobiotic metabolizing enzyme status during lung carcinogenesis of Swiss albino mice induced by benzo(a)pyrene. Fundam Clin Pharmacol. 2014 Jun;28(3):310-22. PMID: 23834621. 

 

Poirier MC, Santella R, Weinstein IB, et al. Quantitation of benzo(a)pyrene-deoxyguanosine adducts by radioimmunoassay. Cancer Res. 1980 Feb;40(2):412-6. PMID: 7356524.

 

Selkirk JK. Benzo[a]pyrene carcinogenesis: a biochemical selection mechanism. J Toxicol Environ Health. 1977 Jul;2(6):1245-58. PMID: 328915." T,N "UN number: 3077     Class:  9     Packing group:  III

Proper shipping name:  Environmentally hazardous substance, solid, n.o.s. (Benzo[a]pyrene) 

Reportable Quantity (RQ): 1lbs.  Marine pollutant:  Poison inhalation hazard:  No"

LKT B1652 Benzo[a]pyrene 1 g 271.7 Polycyclic aromatic hydrocarbon (PAH) found in coal tar, cigarette smoke, and wood smoke; carcinogen. 3,4-Benzpyrene 1,2-benzpyrene; 1,2-benzopyrene, 6,7-benzopyrene; benzo[a]pyrene; BP; 3,4-benzylpyrene; 3,4-benz[a]pyrene 50-32-8 ≥98% 252.32 C20H12 C1=CC=C2C3=C4C(=CC2=C1)C=CC5=C4C(=CC=C5)C=C3 Ambient Ambient Soluble in chloroform, benzene, toluene, xylene and ether.  Insoluble in water. "Gao L, Mai A, Li X, et al. LncRNA-DQ786227-mediated cell malignant transformation induced by benzo(a)pyrene. Toxicol Lett. 2013 Nov 25;223(2):205-10. PMID: 24084393.

 

Naveenkumar C, Raghunandakumar S, Asokkumar S, et al. Mitigating role of baicalein on lysosomal enzymes and xenobiotic metabolizing enzyme status during lung carcinogenesis of Swiss albino mice induced by benzo(a)pyrene. Fundam Clin Pharmacol. 2014 Jun;28(3):310-22. PMID: 23834621. 

 

Poirier MC, Santella R, Weinstein IB, et al. Quantitation of benzo(a)pyrene-deoxyguanosine adducts by radioimmunoassay. Cancer Res. 1980 Feb;40(2):412-6. PMID: 7356524.

 

Selkirk JK. Benzo[a]pyrene carcinogenesis: a biochemical selection mechanism. J Toxicol Environ Health. 1977 Jul;2(6):1245-58. PMID: 328915." T,N "UN number: 3077     Class:  9     Packing group:  III

Proper shipping name:  Environmentally hazardous substance, solid, n.o.s. (Benzo[a]pyrene) 

Reportable Quantity (RQ): 1lbs.  Marine pollutant:  Poison inhalation hazard:  No"

LKT B1653 Benzyl Isothiocyanate 5 g 41.6 ITC found in cruciferous vegetables. Benzene, (isothiocyanatomethyl)- Isothiocyanic acid benzyl ester; 2-Bromo-4-trifluoro- methyl-6-nitrophenyl-isothiocyanate 622-78-6 ≥97% 149.22 C8H7NS C1=CC=C(C=C1)CN=C=S Ambient 4°C Soluble in DMSO, ethanol, or chloroform. "Tang Y, Abe N, Yoshimoto M, et al. Benzyl isothiocyanate inhibits IL-13 expression in human basophilic KU812 cells. Biosci Biotechnol Biochem. 2014 Sep 25:1-5. PMID: 25253661.

 

Kim M, Cho HJ, Kwon GT, et al. Benzyl isothiocyanate suppresses high-fat diet-stimulated mammary tumor progression via the alteration of tumor microenvironments in obesity-resistant BALB/c mice. Mol Carcinog. 2014 Apr 11. [Epub ahead of print]. PMID: 24729546.

 

Steverding D, Michaels S, Read KD. In vitro and in vivo studies of trypanocidal activity of dietary isothiocyanates. Planta Med. 2014 Feb;80(2-3):183-6. PMID: 24452460.

 

Dufour V, Stahl M, Rosenfeld E, et al. Insights into the mode of action of benzyl isothiocyanate on Campylobacter jejuni. Appl Environ Microbiol. 2013 Nov;79(22):6958-68. PMID: 24014524.

 

Huang CS, Lin AH, Liu CT, et al. Isothiocyanates protect against oxidized LDL-induced endothelial dysfunction by upregulating Nrf2-dependent antioxidation and suppressing NFκB activation. Mol Nutr Food Res. 2013 Nov;57(11):1918-30. PMID: 23836589.

 

Lin JF, Tsai TF, Liao PC, et al. Benzyl isothiocyanate induces protective autophagy in human prostate cancer cells via inhibition of mTOR signaling. Carcinogenesis. 2013 Feb;34(2):406-14. PMID: 23172666.

 

Boreddy SR, Sahu RP, Srivastava SK. Benzyl isothiocyanate suppresses pancreatic tumor angiogenesis and invasion by inhibiting HIF-α/VEGF/Rho-GTPases: pivotal role of STAT-3. PLoS One. 2011;6(10):e25799. PMID: 22016776.

 

Warin R, Chambers WH, Potter DM, et al. Prevention of mammary carcinogenesis in MMTV-neu mice by cruciferous vegetable constituent benzyl isothiocyanate. Cancer Res. 2009 Dec 15;69(24):9473-80. PMID: 19934325.

 

Kim SH, Nagalingam A, Saxena NK, et al. Benzyl isothiocyanate inhibits oncogenic actions of leptin in human breast cancer cells by suppressing activation of signal transducer and activator of transcription 3. Carcinogenesis. 2011 Mar;32(3):359-367. PMID: 21163886. 

" Xn, Xi "UN number: 3334     Class:  9     

Proper shipping name:  A aviation regulated liquid, n.o.s. (Benzyl isothiocyanate)

Marine pollutant:  No,  Poison inhalation hazard:  No"

LKT B1653 Benzyl Isothiocyanate 10 g 73.9 ITC found in cruciferous vegetables. Benzene, (isothiocyanatomethyl)- Isothiocyanic acid benzyl ester; 2-Bromo-4-trifluoro- methyl-6-nitrophenyl-isothiocyanate 622-78-6 ≥97% 149.22 C8H7NS C1=CC=C(C=C1)CN=C=S Ambient 4°C Soluble in DMSO, ethanol, or chloroform. "Tang Y, Abe N, Yoshimoto M, et al. Benzyl isothiocyanate inhibits IL-13 expression in human basophilic KU812 cells. Biosci Biotechnol Biochem. 2014 Sep 25:1-5. PMID: 25253661.

 

Kim M, Cho HJ, Kwon GT, et al. Benzyl isothiocyanate suppresses high-fat diet-stimulated mammary tumor progression via the alteration of tumor microenvironments in obesity-resistant BALB/c mice. Mol Carcinog. 2014 Apr 11. [Epub ahead of print]. PMID: 24729546.

 

Steverding D, Michaels S, Read KD. In vitro and in vivo studies of trypanocidal activity of dietary isothiocyanates. Planta Med. 2014 Feb;80(2-3):183-6. PMID: 24452460.

 

Dufour V, Stahl M, Rosenfeld E, et al. Insights into the mode of action of benzyl isothiocyanate on Campylobacter jejuni. Appl Environ Microbiol. 2013 Nov;79(22):6958-68. PMID: 24014524.

 

Huang CS, Lin AH, Liu CT, et al. Isothiocyanates protect against oxidized LDL-induced endothelial dysfunction by upregulating Nrf2-dependent antioxidation and suppressing NFκB activation. Mol Nutr Food Res. 2013 Nov;57(11):1918-30. PMID: 23836589.

 

Lin JF, Tsai TF, Liao PC, et al. Benzyl isothiocyanate induces protective autophagy in human prostate cancer cells via inhibition of mTOR signaling. Carcinogenesis. 2013 Feb;34(2):406-14. PMID: 23172666.

 

Boreddy SR, Sahu RP, Srivastava SK. Benzyl isothiocyanate suppresses pancreatic tumor angiogenesis and invasion by inhibiting HIF-α/VEGF/Rho-GTPases: pivotal role of STAT-3. PLoS One. 2011;6(10):e25799. PMID: 22016776.

 

Warin R, Chambers WH, Potter DM, et al. Prevention of mammary carcinogenesis in MMTV-neu mice by cruciferous vegetable constituent benzyl isothiocyanate. Cancer Res. 2009 Dec 15;69(24):9473-80. PMID: 19934325.

 

Kim SH, Nagalingam A, Saxena NK, et al. Benzyl isothiocyanate inhibits oncogenic actions of leptin in human breast cancer cells by suppressing activation of signal transducer and activator of transcription 3. Carcinogenesis. 2011 Mar;32(3):359-367. PMID: 21163886. 

" Xn, Xi "UN number: 3334     Class:  9     

Proper shipping name:  A aviation regulated liquid, n.o.s. (Benzyl isothiocyanate)

Marine pollutant:  No,  Poison inhalation hazard:  No"

LKT B1654 Benzyl Selenocyanate 50 mg 84.3 Organoselenium compound found in selenium-enriched garlic; potential PKA and PKC inhibitor. "Benzyl selenocyanate

" Selenocyanic acid; benzyl ester; Selenocyanic acid; phenylmethyl ester (9CI) 4671-93-6 ≥98% 196.11 C8H7NSe C1=CC=C(C=C1)C[Se]C#N Ambient 4°C "El-Bayoumy K, Sinha R, Pinto JT, et al. Cancer chemoprevention by garlic and garlic-containing sulfur and selenium compounds. J Nutr. 2006 Mar;136(3 Suppl):864S-869S. PMID: 16484582.

 

Fiala ES, Staretz ME, Pandya GA, et al. Inhibition of DNA cytosine methyltransferase by chemopreventive selenium compounds, determined by an improved assay for DNA cytosine methyltransferase and DNA cytosine methylation. Carcinogenesis. 1998 Apr;19(4):597-604. PMID: 9600343.

 

Foiles P, Fujiki H, Suganuma M, et al. Inhibition of pkc and pka by chemopreventive organoselenium compounds. Int J Oncol. 1995 Sep;7(3):685-90. PMID: 21552892.

"

LKT B1654 Benzyl Selenocyanate 100 mg 149.9 Organoselenium compound found in selenium-enriched garlic; potential PKA and PKC inhibitor. "Benzyl selenocyanate

" Selenocyanic acid; benzyl ester; Selenocyanic acid; phenylmethyl ester (9CI) 4671-93-6 ≥98% 196.11 C8H7NSe C1=CC=C(C=C1)C[Se]C#N Ambient 4°C "El-Bayoumy K, Sinha R, Pinto JT, et al. Cancer chemoprevention by garlic and garlic-containing sulfur and selenium compounds. J Nutr. 2006 Mar;136(3 Suppl):864S-869S. PMID: 16484582.

 

Fiala ES, Staretz ME, Pandya GA, et al. Inhibition of DNA cytosine methyltransferase by chemopreventive selenium compounds, determined by an improved assay for DNA cytosine methyltransferase and DNA cytosine methylation. Carcinogenesis. 1998 Apr;19(4):597-604. PMID: 9600343.

 

Foiles P, Fujiki H, Suganuma M, et al. Inhibition of pkc and pka by chemopreventive organoselenium compounds. Int J Oncol. 1995 Sep;7(3):685-90. PMID: 21552892.

"

LKT B1654 Benzyl Selenocyanate 500 mg 637.6 Organoselenium compound found in selenium-enriched garlic; potential PKA and PKC inhibitor. "Benzyl selenocyanate

" Selenocyanic acid; benzyl ester; Selenocyanic acid; phenylmethyl ester (9CI) 4671-93-6 ≥98% 196.11 C8H7NSe C1=CC=C(C=C1)C[Se]C#N Ambient 4°C "El-Bayoumy K, Sinha R, Pinto JT, et al. Cancer chemoprevention by garlic and garlic-containing sulfur and selenium compounds. J Nutr. 2006 Mar;136(3 Suppl):864S-869S. PMID: 16484582.

 

Fiala ES, Staretz ME, Pandya GA, et al. Inhibition of DNA cytosine methyltransferase by chemopreventive selenium compounds, determined by an improved assay for DNA cytosine methyltransferase and DNA cytosine methylation. Carcinogenesis. 1998 Apr;19(4):597-604. PMID: 9600343.

 

Foiles P, Fujiki H, Suganuma M, et al. Inhibition of pkc and pka by chemopreventive organoselenium compounds. Int J Oncol. 1995 Sep;7(3):685-90. PMID: 21552892.

"

LKT B1655 S-(N-Benzylthiocarbamoyl)-L-cysteine 500 mg 104.5 Cysteine conjugate of benzyl isothiocyanate (BITC); NMDA demethylase inhibitor. L-Cysteine, (phenylmethyl)carbamodithioate (ester) Benzyl isothiocyanate cysteine conjugate 35446-36-7 ≥98% 270.37 C11H14N2O2S2 C1=CC=C(C=C1)CNC(=S)SCC(C(=O)O)N Ambient -20°C Soluble in water. "Tang L, Li G, Song L, et al. The principal urinary metabolites of dietary isothiocyanates, N-acetylcysteine conjugates, elicit the same anti-proliferative response as their parent compounds in human bladder cancer cells. Anticancer Drugs. 2006 Mar;17(3):297-305. PMID: 16520658.

 

Jiao D, Conaway CC, Wang MH, et al. Inhibition of N-nitrosodimethylamine demethylase in rat and human liver microsomes by isothiocyanates and their glutathione, L-cysteine, and N-acetyl-L-cysteine conjugates. Chem Res Toxicol. 1996 Sep;9(6):932-8. PMID: 8870979.

 

Adesida A, Edwards LG, Thornalley PJ. Inhibition of human leukaemia 60 cell growth by mercapturic acid metabolites of phenylethyl isothiocyanate. Food Chem Toxicol. 1996 Apr;34(4):385-92. PMID: 8641665.

" Not dangerous goods.

LKT B1655 S-(N-Benzylthiocarbamoyl)-L-cysteine 1 g 181 Cysteine conjugate of benzyl isothiocyanate (BITC); NMDA demethylase inhibitor. L-Cysteine, (phenylmethyl)carbamodithioate (ester) Benzyl isothiocyanate cysteine conjugate 35446-36-7 ≥98% 270.37 C11H14N2O2S2 C1=CC=C(C=C1)CNC(=S)SCC(C(=O)O)N Ambient -20°C Soluble in water. "Tang L, Li G, Song L, et al. The principal urinary metabolites of dietary isothiocyanates, N-acetylcysteine conjugates, elicit the same anti-proliferative response as their parent compounds in human bladder cancer cells. Anticancer Drugs. 2006 Mar;17(3):297-305. PMID: 16520658.

 

Jiao D, Conaway CC, Wang MH, et al. Inhibition of N-nitrosodimethylamine demethylase in rat and human liver microsomes by isothiocyanates and their glutathione, L-cysteine, and N-acetyl-L-cysteine conjugates. Chem Res Toxicol. 1996 Sep;9(6):932-8. PMID: 8870979.

 

Adesida A, Edwards LG, Thornalley PJ. Inhibition of human leukaemia 60 cell growth by mercapturic acid metabolites of phenylethyl isothiocyanate. Food Chem Toxicol. 1996 Apr;34(4):385-92. PMID: 8641665.

" Not dangerous goods.

LKT B1655 S-(N-Benzylthiocarbamoyl)-L-cysteine 5 g 610.1 Cysteine conjugate of benzyl isothiocyanate (BITC); NMDA demethylase inhibitor. L-Cysteine, (phenylmethyl)carbamodithioate (ester) Benzyl isothiocyanate cysteine conjugate 35446-36-7 ≥98% 270.37 C11H14N2O2S2 C1=CC=C(C=C1)CNC(=S)SCC(C(=O)O)N Ambient -20°C Soluble in water. "Tang L, Li G, Song L, et al. The principal urinary metabolites of dietary isothiocyanates, N-acetylcysteine conjugates, elicit the same anti-proliferative response as their parent compounds in human bladder cancer cells. Anticancer Drugs. 2006 Mar;17(3):297-305. PMID: 16520658.

 

Jiao D, Conaway CC, Wang MH, et al. Inhibition of N-nitrosodimethylamine demethylase in rat and human liver microsomes by isothiocyanates and their glutathione, L-cysteine, and N-acetyl-L-cysteine conjugates. Chem Res Toxicol. 1996 Sep;9(6):932-8. PMID: 8870979.

 

Adesida A, Edwards LG, Thornalley PJ. Inhibition of human leukaemia 60 cell growth by mercapturic acid metabolites of phenylethyl isothiocyanate. Food Chem Toxicol. 1996 Apr;34(4):385-92. PMID: 8641665.

" Not dangerous goods.

LKT B1656 Benzyl Thiocyanate 50 g 71.8 Found in cruciferous vegetables. Benzyl rhodanide 3012-37-1 ≥98% 149.21 C8H7NS C1=CC=C(C=C1)CSC#N Ambient Ambient Insoluble in Water, Soluble in Alcohol and Ether "Musk SR, Stephenson P, Smith TK, et al. Selective toxicity of compounds naturally present in food toward the transformed phenotype of human colorectal cell line HT29. Nutr Cancer. 1995;24(3):289-98. PMID: 8610048.

 

Sugie S, Okamoto K, Okumura A, et al. Inhibitory effects of benzyl thiocyanate and benzyl isothiocyanate on methylazoxymethanol acetate-induced intestinal carcinogenesis in rats. Carcinogenesis. 1994 Aug;15(8):1555-60. PMID: 8055633.

" Xn, T+ "UN number: 3334     Class:  9     Packing group:  III

Proper shipping name:  Aviation regulated liquid, n.o.s. (Benzyl thiocyanate)

Marine pollutant:  No     Poison inhalation hazard:  No"

LKT B1656 Benzyl Thiocyanate 100 g 97.2 Found in cruciferous vegetables. Benzyl rhodanide 3012-37-1 ≥98% 149.21 C8H7NS C1=CC=C(C=C1)CSC#N Ambient Ambient Insoluble in Water, Soluble in Alcohol and Ether "Musk SR, Stephenson P, Smith TK, et al. Selective toxicity of compounds naturally present in food toward the transformed phenotype of human colorectal cell line HT29. Nutr Cancer. 1995;24(3):289-98. PMID: 8610048.

 

Sugie S, Okamoto K, Okumura A, et al. Inhibitory effects of benzyl thiocyanate and benzyl isothiocyanate on methylazoxymethanol acetate-induced intestinal carcinogenesis in rats. Carcinogenesis. 1994 Aug;15(8):1555-60. PMID: 8055633.

" Xn, T+ "UN number: 3334     Class:  9     Packing group:  III

Proper shipping name:  Aviation regulated liquid, n.o.s. (Benzyl thiocyanate)

Marine pollutant:  No     Poison inhalation hazard:  No"

LKT B1668 Berteroin 25 mg 115.5 Thio sulforaphane analog, ITC. 1-Isothiocyanato-5-(methylthio)-pentane "5-Methylthiopentyl isothiocyanate 

" 4430-42-6 ≥97% 175.43 C7H13NS2 CSCCCCCN=C=S Ambient -20°C Soluble in DMSO, ethanol, or chloroform. "Jung YJ, Jung JI, Cho HJ, et al. Berteroin present in cruciferous vegetables exerts potent anti-inflammatory properties in murine macrophages and mouse skin. Int J Mol Sci. 2014 Nov 11;15(11):20686-705. PMID: 25393510.

 

Kim MJ, Kim SH, Lim SJ. Comparison of the apoptosis-inducing capability of sulforaphane analogues in human colon cancer cells. Anticancer Res. 2010 Sep;30(9):3611-9. PMID: 20944144.

 

Kim SH, Singh SV. D,L-Sulforaphane causes transcriptional repression of androgen receptor in human prostate cancer cells. Mol Cancer Ther. 2009 Jul;8(7):1946-54. PMID: 19584240.

" Not dangerous goods.

LKT B1668 Berteroin 50 mg 199.5 Thio sulforaphane analog, ITC. 1-Isothiocyanato-5-(methylthio)-pentane "5-Methylthiopentyl isothiocyanate 

" 4430-42-6 ≥97% 175.43 C7H13NS2 CSCCCCCN=C=S Ambient -20°C Soluble in DMSO, ethanol, or chloroform. "Jung YJ, Jung JI, Cho HJ, et al. Berteroin present in cruciferous vegetables exerts potent anti-inflammatory properties in murine macrophages and mouse skin. Int J Mol Sci. 2014 Nov 11;15(11):20686-705. PMID: 25393510.

 

Kim MJ, Kim SH, Lim SJ. Comparison of the apoptosis-inducing capability of sulforaphane analogues in human colon cancer cells. Anticancer Res. 2010 Sep;30(9):3611-9. PMID: 20944144.

 

Kim SH, Singh SV. D,L-Sulforaphane causes transcriptional repression of androgen receptor in human prostate cancer cells. Mol Cancer Ther. 2009 Jul;8(7):1946-54. PMID: 19584240.

" Not dangerous goods.

LKT B1668 Berteroin 100 mg 346.5 Thio sulforaphane analog, ITC. 1-Isothiocyanato-5-(methylthio)-pentane "5-Methylthiopentyl isothiocyanate 

" 4430-42-6 ≥97% 175.43 C7H13NS2 CSCCCCCN=C=S Ambient -20°C Soluble in DMSO, ethanol, or chloroform. "Jung YJ, Jung JI, Cho HJ, et al. Berteroin present in cruciferous vegetables exerts potent anti-inflammatory properties in murine macrophages and mouse skin. Int J Mol Sci. 2014 Nov 11;15(11):20686-705. PMID: 25393510.

 

Kim MJ, Kim SH, Lim SJ. Comparison of the apoptosis-inducing capability of sulforaphane analogues in human colon cancer cells. Anticancer Res. 2010 Sep;30(9):3611-9. PMID: 20944144.

 

Kim SH, Singh SV. D,L-Sulforaphane causes transcriptional repression of androgen receptor in human prostate cancer cells. Mol Cancer Ther. 2009 Jul;8(7):1946-54. PMID: 19584240.

" Not dangerous goods.

LKT B1668 Berteroin 500 mg 1155 Thio sulforaphane analog, ITC. 1-Isothiocyanato-5-(methylthio)-pentane "5-Methylthiopentyl isothiocyanate 

" 4430-42-6 ≥97% 175.43 C7H13NS2 CSCCCCCN=C=S Ambient -20°C Soluble in DMSO, ethanol, or chloroform. "Jung YJ, Jung JI, Cho HJ, et al. Berteroin present in cruciferous vegetables exerts potent anti-inflammatory properties in murine macrophages and mouse skin. Int J Mol Sci. 2014 Nov 11;15(11):20686-705. PMID: 25393510.

 

Kim MJ, Kim SH, Lim SJ. Comparison of the apoptosis-inducing capability of sulforaphane analogues in human colon cancer cells. Anticancer Res. 2010 Sep;30(9):3611-9. PMID: 20944144.

 

Kim SH, Singh SV. D,L-Sulforaphane causes transcriptional repression of androgen receptor in human prostate cancer cells. Mol Cancer Ther. 2009 Jul;8(7):1946-54. PMID: 19584240.

" Not dangerous goods.

LKT B3373 Bis(aziridinyl)methylamino Phosphine Sulfide 500 mg 99.9 Insect sterilizer; mutagenic. Bis(aziridinyl)methylamino phosphine sulfide Bisazir 13687-09-7 ≥98% 177.21 C5H12N3PS CNP(=S)(N1CC1)N2CC2 Dry Ice -20°C Soluble in DMSO. "Ciereszko A, Wolfe TD, Dabrowski K. Analysis of DNA damage in sea lamprey (Petromyzon marinus) spermatozoa by UV, hydrogen peroxide, and the toxicant bisazir. Theriogenology. Aquat Toxicol. 2005 Jun 15;73(2):128-38. PMID: 15885821.

 

Ciereszko A, Babiak I, Dabrowski K. Efficacy of animal anti-fertility compounds against sea lamprey (Petromyzon marinus) spermatozoa. Theriogenology. 2004 Apr 15;61(6):1039-50. PMID: 15036993.

 

Srivastava VK, Kumar K. Effect of the chemosterilant bisazir on the testes of the spotted bollworm Earias fabia stoll. Toxicology. 1984 Jun;31(3-4):335-42. PMID: 6740707.

" Not dangerous goods.

LKT B3373 Bis(aziridinyl)methylamino Phosphine Sulfide 1 g 168.6 Insect sterilizer; mutagenic. Bis(aziridinyl)methylamino phosphine sulfide Bisazir 13687-09-7 ≥98% 177.21 C5H12N3PS CNP(=S)(N1CC1)N2CC2 Dry Ice -20°C Soluble in DMSO. "Ciereszko A, Wolfe TD, Dabrowski K. Analysis of DNA damage in sea lamprey (Petromyzon marinus) spermatozoa by UV, hydrogen peroxide, and the toxicant bisazir. Theriogenology. Aquat Toxicol. 2005 Jun 15;73(2):128-38. PMID: 15885821.

 

Ciereszko A, Babiak I, Dabrowski K. Efficacy of animal anti-fertility compounds against sea lamprey (Petromyzon marinus) spermatozoa. Theriogenology. 2004 Apr 15;61(6):1039-50. PMID: 15036993.

 

Srivastava VK, Kumar K. Effect of the chemosterilant bisazir on the testes of the spotted bollworm Earias fabia stoll. Toxicology. 1984 Jun;31(3-4):335-42. PMID: 6740707.

" Not dangerous goods.

LKT B3373 Bis(aziridinyl)methylamino Phosphine Sulfide 5 g 670.2 Insect sterilizer; mutagenic. Bis(aziridinyl)methylamino phosphine sulfide Bisazir 13687-09-7 ≥98% 177.21 C5H12N3PS CNP(=S)(N1CC1)N2CC2 Dry Ice -20°C Soluble in DMSO. "Ciereszko A, Wolfe TD, Dabrowski K. Analysis of DNA damage in sea lamprey (Petromyzon marinus) spermatozoa by UV, hydrogen peroxide, and the toxicant bisazir. Theriogenology. Aquat Toxicol. 2005 Jun 15;73(2):128-38. PMID: 15885821.

 

Ciereszko A, Babiak I, Dabrowski K. Efficacy of animal anti-fertility compounds against sea lamprey (Petromyzon marinus) spermatozoa. Theriogenology. 2004 Apr 15;61(6):1039-50. PMID: 15036993.

 

Srivastava VK, Kumar K. Effect of the chemosterilant bisazir on the testes of the spotted bollworm Earias fabia stoll. Toxicology. 1984 Jun;31(3-4):335-42. PMID: 6740707.

" Not dangerous goods.

LKT B3272 Bis(3,5-dibromosalicyl) Fumarate 100 mg 27.6 Aspirin analog; hemoglobin chain cross-linker. 2-Butenedioic acid (E)-, bis(2,4-dibromo-6-carboxyphenyl) ester "3,5-Dibromosalicyl-bis-fumarate 

" 71337-53-6 ≥91% 671.87 C18H8O8Br4 C1=C(C=C(C(=C1Br)OC(=O)C=CC(=O)OC2=C(C=C(C=C2C(=O)O)Br)Br)C(=O)O)Br Ambient -20°C "Macdonald VW, Motterlini R. Vasoconstrictor effects in isolated rabbit heart perfused with bis(3,5-dibromosalicyl)fumarate cross-linked hemoglobin (alpha alpha Hb). Artif Cells Blood Substit Immobil Biotechnol. 1994;22(3):565-75. PMID: 7994376.

 

Thompson EB, Klotz IM. Pharmacological actions of diaspirins, potential antisickling agents: analgesic and anti-inflammatory effects. Res Commun Chem Pathol Pharmacol. 1985 Jun;48(3):381-8. PMID: 4023420.

 

Chatterjee R, Iwai Y, Walder RY, et al. Structural features required for the reactivity and intracellular transport of bis(3,5-dibromosalicyl)fumarate and related anti-sickling compounds that modify hemoglobin S at the 2,3-diphosphoglycerate binding site. J Biol Chem. 1984 Dec 10;259(23):14863-73. PMID: 6501320.

" Not dangerous goods.

LKT B3272 Bis(3,5-dibromosalicyl) Fumarate 500 mg 96.2 Aspirin analog; hemoglobin chain cross-linker. 2-Butenedioic acid (E)-, bis(2,4-dibromo-6-carboxyphenyl) ester "3,5-Dibromosalicyl-bis-fumarate 

" 71337-53-6 ≥91% 671.87 C18H8O8Br4 C1=C(C=C(C(=C1Br)OC(=O)C=CC(=O)OC2=C(C=C(C=C2C(=O)O)Br)Br)C(=O)O)Br Ambient -20°C "Macdonald VW, Motterlini R. Vasoconstrictor effects in isolated rabbit heart perfused with bis(3,5-dibromosalicyl)fumarate cross-linked hemoglobin (alpha alpha Hb). Artif Cells Blood Substit Immobil Biotechnol. 1994;22(3):565-75. PMID: 7994376.

 

Thompson EB, Klotz IM. Pharmacological actions of diaspirins, potential antisickling agents: analgesic and anti-inflammatory effects. Res Commun Chem Pathol Pharmacol. 1985 Jun;48(3):381-8. PMID: 4023420.

 

Chatterjee R, Iwai Y, Walder RY, et al. Structural features required for the reactivity and intracellular transport of bis(3,5-dibromosalicyl)fumarate and related anti-sickling compounds that modify hemoglobin S at the 2,3-diphosphoglycerate binding site. J Biol Chem. 1984 Dec 10;259(23):14863-73. PMID: 6501320.

" Not dangerous goods.

LKT B3272 Bis(3,5-dibromosalicyl) Fumarate 1 g 137.1 Aspirin analog; hemoglobin chain cross-linker. 2-Butenedioic acid (E)-, bis(2,4-dibromo-6-carboxyphenyl) ester "3,5-Dibromosalicyl-bis-fumarate 

" 71337-53-6 ≥91% 671.87 C18H8O8Br4 C1=C(C=C(C(=C1Br)OC(=O)C=CC(=O)OC2=C(C=C(C=C2C(=O)O)Br)Br)C(=O)O)Br Ambient -20°C "Macdonald VW, Motterlini R. Vasoconstrictor effects in isolated rabbit heart perfused with bis(3,5-dibromosalicyl)fumarate cross-linked hemoglobin (alpha alpha Hb). Artif Cells Blood Substit Immobil Biotechnol. 1994;22(3):565-75. PMID: 7994376.

 

Thompson EB, Klotz IM. Pharmacological actions of diaspirins, potential antisickling agents: analgesic and anti-inflammatory effects. Res Commun Chem Pathol Pharmacol. 1985 Jun;48(3):381-8. PMID: 4023420.

 

Chatterjee R, Iwai Y, Walder RY, et al. Structural features required for the reactivity and intracellular transport of bis(3,5-dibromosalicyl)fumarate and related anti-sickling compounds that modify hemoglobin S at the 2,3-diphosphoglycerate binding site. J Biol Chem. 1984 Dec 10;259(23):14863-73. PMID: 6501320.

" Not dangerous goods.

LKT B3272 Bis(3,5-dibromosalicyl) Fumarate 5 g 274.7 Aspirin analog; hemoglobin chain cross-linker. 2-Butenedioic acid (E)-, bis(2,4-dibromo-6-carboxyphenyl) ester "3,5-Dibromosalicyl-bis-fumarate 

" 71337-53-6 ≥91% 671.87 C18H8O8Br4 C1=C(C=C(C(=C1Br)OC(=O)C=CC(=O)OC2=C(C=C(C=C2C(=O)O)Br)Br)C(=O)O)Br Ambient -20°C "Macdonald VW, Motterlini R. Vasoconstrictor effects in isolated rabbit heart perfused with bis(3,5-dibromosalicyl)fumarate cross-linked hemoglobin (alpha alpha Hb). Artif Cells Blood Substit Immobil Biotechnol. 1994;22(3):565-75. PMID: 7994376.

 

Thompson EB, Klotz IM. Pharmacological actions of diaspirins, potential antisickling agents: analgesic and anti-inflammatory effects. Res Commun Chem Pathol Pharmacol. 1985 Jun;48(3):381-8. PMID: 4023420.

 

Chatterjee R, Iwai Y, Walder RY, et al. Structural features required for the reactivity and intracellular transport of bis(3,5-dibromosalicyl)fumarate and related anti-sickling compounds that modify hemoglobin S at the 2,3-diphosphoglycerate binding site. J Biol Chem. 1984 Dec 10;259(23):14863-73. PMID: 6501320.

" Not dangerous goods.

LKT B3275 Bis(3,5-dibromosalicyl) Succinate 100 mg 27.6 Aspirin analog; hemoglobin chain cross-linker. 3,5-dibromo-2-[4-(2,4-dibromo-6-carboxyphenoxy)-4-oxobutanoyl]oxybenzoic acid 71337-52-5 ≥95% 673.89 C18H10O8Br4 c1c(cc(c(c1C(=O)O)OC(=O)CCC(=O)Oc2c(cc(cc2Br)Br)C(=O)O)Br)Br Ambient -20°C "Macdonald VW, Motterlini R. Vasoconstrictor effects in isolated rabbit heart perfused with bis(3,5-dibromosalicyl)fumarate cross-linked hemoglobin (alpha alpha Hb). Artif Cells Blood Substit Immobil Biotechnol. 1994;22(3):565-75. PMID: 7994376.

 

Thompson EB, Klotz IM. Pharmacological actions of diaspirins, potential antisickling agents: analgesic and anti-inflammatory effects. Res Commun Chem Pathol Pharmacol. 1985 Jun;48(3):381-8. PMID: 4023420.

 

Chatterjee R, Iwai Y, Walder RY, et al. Structural features required for the reactivity and intracellular transport of bis(3,5-dibromosalicyl)fumarate and related anti-sickling compounds that modify hemoglobin S at the 2,3-diphosphoglycerate binding site. J Biol Chem. 1984 Dec 10;259(23):14863-73. PMID: 6501320.

" Not dangerous goods.

LKT B3275 Bis(3,5-dibromosalicyl) Succinate 500 mg 96.2 Aspirin analog; hemoglobin chain cross-linker. 3,5-dibromo-2-[4-(2,4-dibromo-6-carboxyphenoxy)-4-oxobutanoyl]oxybenzoic acid 71337-52-5 ≥95% 673.89 C18H10O8Br4 c1c(cc(c(c1C(=O)O)OC(=O)CCC(=O)Oc2c(cc(cc2Br)Br)C(=O)O)Br)Br Ambient -20°C "Macdonald VW, Motterlini R. Vasoconstrictor effects in isolated rabbit heart perfused with bis(3,5-dibromosalicyl)fumarate cross-linked hemoglobin (alpha alpha Hb). Artif Cells Blood Substit Immobil Biotechnol. 1994;22(3):565-75. PMID: 7994376.

 

Thompson EB, Klotz IM. Pharmacological actions of diaspirins, potential antisickling agents: analgesic and anti-inflammatory effects. Res Commun Chem Pathol Pharmacol. 1985 Jun;48(3):381-8. PMID: 4023420.

 

Chatterjee R, Iwai Y, Walder RY, et al. Structural features required for the reactivity and intracellular transport of bis(3,5-dibromosalicyl)fumarate and related anti-sickling compounds that modify hemoglobin S at the 2,3-diphosphoglycerate binding site. J Biol Chem. 1984 Dec 10;259(23):14863-73. PMID: 6501320.

" Not dangerous goods.

LKT B3275 Bis(3,5-dibromosalicyl) Succinate 1 g 137.1 Aspirin analog; hemoglobin chain cross-linker. 3,5-dibromo-2-[4-(2,4-dibromo-6-carboxyphenoxy)-4-oxobutanoyl]oxybenzoic acid 71337-52-5 ≥95% 673.89 C18H10O8Br4 c1c(cc(c(c1C(=O)O)OC(=O)CCC(=O)Oc2c(cc(cc2Br)Br)C(=O)O)Br)Br Ambient -20°C "Macdonald VW, Motterlini R. Vasoconstrictor effects in isolated rabbit heart perfused with bis(3,5-dibromosalicyl)fumarate cross-linked hemoglobin (alpha alpha Hb). Artif Cells Blood Substit Immobil Biotechnol. 1994;22(3):565-75. PMID: 7994376.

 

Thompson EB, Klotz IM. Pharmacological actions of diaspirins, potential antisickling agents: analgesic and anti-inflammatory effects. Res Commun Chem Pathol Pharmacol. 1985 Jun;48(3):381-8. PMID: 4023420.

 

Chatterjee R, Iwai Y, Walder RY, et al. Structural features required for the reactivity and intracellular transport of bis(3,5-dibromosalicyl)fumarate and related anti-sickling compounds that modify hemoglobin S at the 2,3-diphosphoglycerate binding site. J Biol Chem. 1984 Dec 10;259(23):14863-73. PMID: 6501320.

" Not dangerous goods.

LKT B3275 Bis(3,5-dibromosalicyl) Succinate 5 g 274.7 Aspirin analog; hemoglobin chain cross-linker. 3,5-dibromo-2-[4-(2,4-dibromo-6-carboxyphenoxy)-4-oxobutanoyl]oxybenzoic acid 71337-52-5 ≥95% 673.89 C18H10O8Br4 c1c(cc(c(c1C(=O)O)OC(=O)CCC(=O)Oc2c(cc(cc2Br)Br)C(=O)O)Br)Br Ambient -20°C "Macdonald VW, Motterlini R. Vasoconstrictor effects in isolated rabbit heart perfused with bis(3,5-dibromosalicyl)fumarate cross-linked hemoglobin (alpha alpha Hb). Artif Cells Blood Substit Immobil Biotechnol. 1994;22(3):565-75. PMID: 7994376.

 

Thompson EB, Klotz IM. Pharmacological actions of diaspirins, potential antisickling agents: analgesic and anti-inflammatory effects. Res Commun Chem Pathol Pharmacol. 1985 Jun;48(3):381-8. PMID: 4023420.

 

Chatterjee R, Iwai Y, Walder RY, et al. Structural features required for the reactivity and intracellular transport of bis(3,5-dibromosalicyl)fumarate and related anti-sickling compounds that modify hemoglobin S at the 2,3-diphosphoglycerate binding site. J Biol Chem. 1984 Dec 10;259(23):14863-73. PMID: 6501320.

" Not dangerous goods.

LKT B3280 Bis(salicyl) Fumarate 100 mg 27.6 Aspirin analog; hemoglobin chain cross-linker. ≥98% 356.29 C18H12O8 Ambient -20°C "Macdonald VW, Motterlini R. Vasoconstrictor effects in isolated rabbit heart perfused with bis(3,5-dibromosalicyl)fumarate cross-linked hemoglobin (alpha alpha Hb). Artif Cells Blood Substit Immobil Biotechnol. 1994;22(3):565-75. PMID: 7994376.

 

Thompson EB, Klotz IM. Pharmacological actions of diaspirins, potential antisickling agents: analgesic and anti-inflammatory effects. Res Commun Chem Pathol Pharmacol. 1985 Jun;48(3):381-8. PMID: 4023420.

 

Chatterjee R, Iwai Y, Walder RY, et al. Structural features required for the reactivity and intracellular transport of bis(3,5-dibromosalicyl)fumarate and related anti-sickling compounds that modify hemoglobin S at the 2,3-diphosphoglycerate binding site. J Biol Chem. 1984 Dec 10;259(23):14863-73. PMID: 6501320.

" Not dangerous goods.

LKT B3280 Bis(salicyl) Fumarate 500 mg 96.2 Aspirin analog; hemoglobin chain cross-linker. ≥98% 356.29 C18H12O8 Ambient -20°C "Macdonald VW, Motterlini R. Vasoconstrictor effects in isolated rabbit heart perfused with bis(3,5-dibromosalicyl)fumarate cross-linked hemoglobin (alpha alpha Hb). Artif Cells Blood Substit Immobil Biotechnol. 1994;22(3):565-75. PMID: 7994376.

 

Thompson EB, Klotz IM. Pharmacological actions of diaspirins, potential antisickling agents: analgesic and anti-inflammatory effects. Res Commun Chem Pathol Pharmacol. 1985 Jun;48(3):381-8. PMID: 4023420.

 

Chatterjee R, Iwai Y, Walder RY, et al. Structural features required for the reactivity and intracellular transport of bis(3,5-dibromosalicyl)fumarate and related anti-sickling compounds that modify hemoglobin S at the 2,3-diphosphoglycerate binding site. J Biol Chem. 1984 Dec 10;259(23):14863-73. PMID: 6501320.

" Not dangerous goods.

LKT B3280 Bis(salicyl) Fumarate 1 g 137.1 Aspirin analog; hemoglobin chain cross-linker. ≥98% 356.29 C18H12O8 Ambient -20°C "Macdonald VW, Motterlini R. Vasoconstrictor effects in isolated rabbit heart perfused with bis(3,5-dibromosalicyl)fumarate cross-linked hemoglobin (alpha alpha Hb). Artif Cells Blood Substit Immobil Biotechnol. 1994;22(3):565-75. PMID: 7994376.

 

Thompson EB, Klotz IM. Pharmacological actions of diaspirins, potential antisickling agents: analgesic and anti-inflammatory effects. Res Commun Chem Pathol Pharmacol. 1985 Jun;48(3):381-8. PMID: 4023420.

 

Chatterjee R, Iwai Y, Walder RY, et al. Structural features required for the reactivity and intracellular transport of bis(3,5-dibromosalicyl)fumarate and related anti-sickling compounds that modify hemoglobin S at the 2,3-diphosphoglycerate binding site. J Biol Chem. 1984 Dec 10;259(23):14863-73. PMID: 6501320.

" Not dangerous goods.

LKT B3280 Bis(salicyl) Fumarate 5 g 274.7 Aspirin analog; hemoglobin chain cross-linker. ≥98% 356.29 C18H12O8 Ambient -20°C "Macdonald VW, Motterlini R. Vasoconstrictor effects in isolated rabbit heart perfused with bis(3,5-dibromosalicyl)fumarate cross-linked hemoglobin (alpha alpha Hb). Artif Cells Blood Substit Immobil Biotechnol. 1994;22(3):565-75. PMID: 7994376.

 

Thompson EB, Klotz IM. Pharmacological actions of diaspirins, potential antisickling agents: analgesic and anti-inflammatory effects. Res Commun Chem Pathol Pharmacol. 1985 Jun;48(3):381-8. PMID: 4023420.

 

Chatterjee R, Iwai Y, Walder RY, et al. Structural features required for the reactivity and intracellular transport of bis(3,5-dibromosalicyl)fumarate and related anti-sickling compounds that modify hemoglobin S at the 2,3-diphosphoglycerate binding site. J Biol Chem. 1984 Dec 10;259(23):14863-73. PMID: 6501320.

" Not dangerous goods.

LKT B6801 Brassinin 50 mg 144.1 Phytoalexin, indole found in cruciferous vegetables; indoleamine-2,3-dioxygenase inhibitor. methyl (1H-indol-3-ylmethylamino)methanedithioate methyl N-(1H-indol-3-ylmethyl)-carbamodithioate 105748-59-2 ≥98% 236.36 C11H12N2S2 CSC(=S)NCC1=CNC2=CC=CC=C21 Ambient -20°C Soluble in DMSO. "Kim SM, Park JH, Kim KD, et al. Brassinin induces apoptosis in PC-3 human prostate cancer cells through the suppression of PI3K/Akt/mTOR/S6K1 signaling cascades. Phytother Res. 2014 Mar;28(3):423-31. PMID: 23686889.

 

Banerjee T, Duhadaway JB, Gaspari P, et al. A key in vivo antitumor mechanism of action of natural product-based brassinins is inhibition of indoleamine 2,3-dioxygenase. Oncogene. 2008 May 1;27(20):2851-7. PMID: 18026137.

 

Mehta RG, Liu J, Constantinou A, et al. Cancer chemopreventive activity of brassinin, a phytoalexin from cabbage. Carcinogenesis. 1995 Feb;16(2):399-404. PMID: 7859373.

" Not dangerous goods.

LKT B6801 Brassinin 100 mg 230.7 Phytoalexin, indole found in cruciferous vegetables; indoleamine-2,3-dioxygenase inhibitor. methyl (1H-indol-3-ylmethylamino)methanedithioate methyl N-(1H-indol-3-ylmethyl)-carbamodithioate 105748-59-2 ≥98% 236.36 C11H12N2S2 CSC(=S)NCC1=CNC2=CC=CC=C21 Ambient -20°C Soluble in DMSO. "Kim SM, Park JH, Kim KD, et al. Brassinin induces apoptosis in PC-3 human prostate cancer cells through the suppression of PI3K/Akt/mTOR/S6K1 signaling cascades. Phytother Res. 2014 Mar;28(3):423-31. PMID: 23686889.

 

Banerjee T, Duhadaway JB, Gaspari P, et al. A key in vivo antitumor mechanism of action of natural product-based brassinins is inhibition of indoleamine 2,3-dioxygenase. Oncogene. 2008 May 1;27(20):2851-7. PMID: 18026137.

 

Mehta RG, Liu J, Constantinou A, et al. Cancer chemopreventive activity of brassinin, a phytoalexin from cabbage. Carcinogenesis. 1995 Feb;16(2):399-404. PMID: 7859373.

" Not dangerous goods.

LKT B6801 Brassinin 250 mg 480.3 Phytoalexin, indole found in cruciferous vegetables; indoleamine-2,3-dioxygenase inhibitor. methyl (1H-indol-3-ylmethylamino)methanedithioate methyl N-(1H-indol-3-ylmethyl)-carbamodithioate 105748-59-2 ≥98% 236.36 C11H12N2S2 CSC(=S)NCC1=CNC2=CC=CC=C21 Ambient -20°C Soluble in DMSO. "Kim SM, Park JH, Kim KD, et al. Brassinin induces apoptosis in PC-3 human prostate cancer cells through the suppression of PI3K/Akt/mTOR/S6K1 signaling cascades. Phytother Res. 2014 Mar;28(3):423-31. PMID: 23686889.

 

Banerjee T, Duhadaway JB, Gaspari P, et al. A key in vivo antitumor mechanism of action of natural product-based brassinins is inhibition of indoleamine 2,3-dioxygenase. Oncogene. 2008 May 1;27(20):2851-7. PMID: 18026137.

 

Mehta RG, Liu J, Constantinou A, et al. Cancer chemopreventive activity of brassinin, a phytoalexin from cabbage. Carcinogenesis. 1995 Feb;16(2):399-404. PMID: 7859373.

" Not dangerous goods.

LKT B6856 5-Bromo-2′-Deoxyuridine 250 mg 40.3 Nucleoside (thymidine) analog. 5-Bromo-2'-deoxyuridine Broxuridine; 5-bromouracil deoxyriboside; BUdR; Broxine; Neomark; Radibud 59-14-3 ≥98% 307.11 C9H11BrN2O5 C1C(C(OC1N2C=C(C(=O)NC2=O)Br)CO)O Ambient -20°C Soluble in dimethyl- acetamide, 1N NaOH, or dimethylsulfoxide. Slightly soluble in water. "Zhang R, Zhang J, Fang L, et al. Neuroprotective effects of sulforaphane on cholinergic neurons in mice with Alzheimer's disease-like lesions. Int J Mol Sci. 2014 Aug 18;15(8):14396-410. PMID: 25196440.

 

Jeong CH, Kim SM, Lim JY, et al. Mesenchymal stem cells expressing brain-derived neurotrophic factor enhance endogenous neurogenesis in an ischemic stroke model. Biomed Res Int. 2014;2014:129145. PMID: 24672780.

 

Russo A, Gianni L, Kinsella TJ, et al. Pharmacological evaluation of intravenous delivery of 5-bromodeoxyuridine to patients with brain tumors. Cancer Res. 1984 Apr;44(4):1702-5. PMID: 6704976.

" Xn, Xi Not dangerous goods.

LKT B6856 5-Bromo-2′-Deoxyuridine 500 mg 64.4 Nucleoside (thymidine) analog. 5-Bromo-2'-deoxyuridine Broxuridine; 5-bromouracil deoxyriboside; BUdR; Broxine; Neomark; Radibud 59-14-3 ≥98% 307.11 C9H11BrN2O5 C1C(C(OC1N2C=C(C(=O)NC2=O)Br)CO)O Ambient -20°C Soluble in dimethyl- acetamide, 1N NaOH, or dimethylsulfoxide. Slightly soluble in water. "Zhang R, Zhang J, Fang L, et al. Neuroprotective effects of sulforaphane on cholinergic neurons in mice with Alzheimer's disease-like lesions. Int J Mol Sci. 2014 Aug 18;15(8):14396-410. PMID: 25196440.

 

Jeong CH, Kim SM, Lim JY, et al. Mesenchymal stem cells expressing brain-derived neurotrophic factor enhance endogenous neurogenesis in an ischemic stroke model. Biomed Res Int. 2014;2014:129145. PMID: 24672780.

 

Russo A, Gianni L, Kinsella TJ, et al. Pharmacological evaluation of intravenous delivery of 5-bromodeoxyuridine to patients with brain tumors. Cancer Res. 1984 Apr;44(4):1702-5. PMID: 6704976.

" Xn, Xi Not dangerous goods.

LKT B6856 5-Bromo-2′-Deoxyuridine 1 g 108.9 Nucleoside (thymidine) analog. 5-Bromo-2'-deoxyuridine Broxuridine; 5-bromouracil deoxyriboside; BUdR; Broxine; Neomark; Radibud 59-14-3 ≥98% 307.11 C9H11BrN2O5 C1C(C(OC1N2C=C(C(=O)NC2=O)Br)CO)O Ambient -20°C Soluble in dimethyl- acetamide, 1N NaOH, or dimethylsulfoxide. Slightly soluble in water. "Zhang R, Zhang J, Fang L, et al. Neuroprotective effects of sulforaphane on cholinergic neurons in mice with Alzheimer's disease-like lesions. Int J Mol Sci. 2014 Aug 18;15(8):14396-410. PMID: 25196440.

 

Jeong CH, Kim SM, Lim JY, et al. Mesenchymal stem cells expressing brain-derived neurotrophic factor enhance endogenous neurogenesis in an ischemic stroke model. Biomed Res Int. 2014;2014:129145. PMID: 24672780.

 

Russo A, Gianni L, Kinsella TJ, et al. Pharmacological evaluation of intravenous delivery of 5-bromodeoxyuridine to patients with brain tumors. Cancer Res. 1984 Apr;44(4):1702-5. PMID: 6704976.

" Xn, Xi Not dangerous goods.

LKT B6856 5-Bromo-2′-Deoxyuridine 5 g 353.3 Nucleoside (thymidine) analog. 5-Bromo-2'-deoxyuridine Broxuridine; 5-bromouracil deoxyriboside; BUdR; Broxine; Neomark; Radibud 59-14-3 ≥98% 307.11 C9H11BrN2O5 C1C(C(OC1N2C=C(C(=O)NC2=O)Br)CO)O Ambient -20°C Soluble in dimethyl- acetamide, 1N NaOH, or dimethylsulfoxide. Slightly soluble in water. "Zhang R, Zhang J, Fang L, et al. Neuroprotective effects of sulforaphane on cholinergic neurons in mice with Alzheimer's disease-like lesions. Int J Mol Sci. 2014 Aug 18;15(8):14396-410. PMID: 25196440.

 

Jeong CH, Kim SM, Lim JY, et al. Mesenchymal stem cells expressing brain-derived neurotrophic factor enhance endogenous neurogenesis in an ischemic stroke model. Biomed Res Int. 2014;2014:129145. PMID: 24672780.

 

Russo A, Gianni L, Kinsella TJ, et al. Pharmacological evaluation of intravenous delivery of 5-bromodeoxyuridine to patients with brain tumors. Cancer Res. 1984 Apr;44(4):1702-5. PMID: 6704976.

" Xn, Xi Not dangerous goods.

LKT B7973 Busulfan 10 g 30.2 Alkyl sulfonate; DNA alkylator. 1,4-Butanediol dimethanesulfonate esters Busulphan 55-98-1 ≥98% 246.3 C6H14O6S2 CS(=O)(=O)OCCCCOS(=O)(=O)C Ambient Ambient Soluble in acetone (22 mg/mL), ethanol, or DMSO. Insoluble in water. "Galaup A, Paci A. Pharmacology of dimethanesulfonate alkylating agents: busulfan and treosulfan. Expert Opin Drug Metab Toxicol. 2013 Mar;9(3):333-47. PMID: 23157726.

 

Probin V, Wang Y, Zhou D. Busulfan-induced senescence is dependent on ROS production upstream of the MAPK pathway. Free Radic Biol Med. 2007 Jun 15;42(12):1858-65. PMID: 17512465.

 

Frame D. Chronic myeloid leukemia: standard treatment options. Am J Health Syst Pharm. 2006 Dec 1;63(23 Suppl 8):S10-4; quiz S21-2. PMID: 17106015.

 

Iwamoto T, Hiraku Y, Oikawa S, et al. DNA intrastrand cross-link at the 5'-GA-3' sequence formed by busulfan and its role in the cytotoxic effect. Cancer Sci. 2004 May;95(5):454-8. PMID: 15132775.

" Carc., T, Repr. T+, Xi, Mut. "UN number: 2811     Class:  6.1     Packing group:  III

Proper shipping name:  Toxic solids, organic, n.o.s. (Busulfan)

Marine pollutant:  No     Poison inhalation hazard:  No"

LKT B7973 Busulfan 25 g 60.5 Alkyl sulfonate; DNA alkylator. 1,4-Butanediol dimethanesulfonate esters Busulphan 55-98-1 ≥98% 246.3 C6H14O6S2 CS(=O)(=O)OCCCCOS(=O)(=O)C Ambient Ambient Soluble in acetone (22 mg/mL), ethanol, or DMSO. Insoluble in water. "Galaup A, Paci A. Pharmacology of dimethanesulfonate alkylating agents: busulfan and treosulfan. Expert Opin Drug Metab Toxicol. 2013 Mar;9(3):333-47. PMID: 23157726.

 

Probin V, Wang Y, Zhou D. Busulfan-induced senescence is dependent on ROS production upstream of the MAPK pathway. Free Radic Biol Med. 2007 Jun 15;42(12):1858-65. PMID: 17512465.

 

Frame D. Chronic myeloid leukemia: standard treatment options. Am J Health Syst Pharm. 2006 Dec 1;63(23 Suppl 8):S10-4; quiz S21-2. PMID: 17106015.

 

Iwamoto T, Hiraku Y, Oikawa S, et al. DNA intrastrand cross-link at the 5'-GA-3' sequence formed by busulfan and its role in the cytotoxic effect. Cancer Sci. 2004 May;95(5):454-8. PMID: 15132775.

" Carc., T, Repr. T+, Xi, Mut. "UN number: 2811     Class:  6.1     Packing group:  III

Proper shipping name:  Toxic solids, organic, n.o.s. (Busulfan)

Marine pollutant:  No     Poison inhalation hazard:  No"

LKT B7977 Butylated Hydroxytoluene 100 g 34.8 Antioxidative food and cosmetics additive. 2,6-Bis-(1,1-dimethylethyl)-4-methylphenol BHT; Antracine 8; Ionol CP; Sustane; Dalpac; Impruvol; Vianol 128-37-0 ≥98% 220.35 C15H24O CC1=CC(=C(C(=C1)C(C)(C)C)O)C(C)(C)C Ambient Ambient Insoluble in water.  Soluble in ethanol, acetone, or DMSO. "Lee JH, Jung MY. Direct spectroscopic observation of singlet oxygen quenching and kinetic studies of physical and chemical singlet oxygen quenching rate constants of synthetic antioxidants (BHA, BHT, and TBHQ) in methanol. J Food Sci. 2010 Aug 1;75(6):C506-13. PMID: 20722904.

 

Crews F, Nixon K, Kim D, et al. BHT blocks NF-kappaB activation and ethanol-induced brain damage. Alcohol Clin Exp Res. 2006 Nov;30(11):1938-49. PMID: 17067360.

" Xn, Xi Not dangerous goods.

LKT B7977 Butylated Hydroxytoluene 500 g 84.3 Antioxidative food and cosmetics additive. 2,6-Bis-(1,1-dimethylethyl)-4-methylphenol BHT; Antracine 8; Ionol CP; Sustane; Dalpac; Impruvol; Vianol 128-37-0 ≥98% 220.35 C15H24O CC1=CC(=C(C(=C1)C(C)(C)C)O)C(C)(C)C Ambient Ambient Insoluble in water.  Soluble in ethanol, acetone, or DMSO. "Lee JH, Jung MY. Direct spectroscopic observation of singlet oxygen quenching and kinetic studies of physical and chemical singlet oxygen quenching rate constants of synthetic antioxidants (BHA, BHT, and TBHQ) in methanol. J Food Sci. 2010 Aug 1;75(6):C506-13. PMID: 20722904.

 

Crews F, Nixon K, Kim D, et al. BHT blocks NF-kappaB activation and ethanol-induced brain damage. Alcohol Clin Exp Res. 2006 Nov;30(11):1938-49. PMID: 17067360.

" Xn, Xi Not dangerous goods.

LKT B8070 2-tert-Butyl-4-Hydroxyanisole                          100 mg 100.6 BHA derivative, antioxidative food and cosmetics additive. 2-(1,1-Di-methylethyl)4-methoxyphenol 2-BHA 88-32-4 ≥99% 180.25 C11H16O2 CC(C)(C)C1=C(C=CC(=C1)O)OC Ambient Ambient Insoluble in water. Soluble in ethanol, acetone, or DMSO. "Hwang GH, Jeon YJ, Han HJ, et al. Protective effect of butylated hydroxylanisole against hydrogen peroxide-induced apoptosis in primary cultured mouse hepatocytes. J Vet Sci. 2014 Oct 8. [Epub ahead of print]. PMID: 25293491.

 

Nishiya H, Haga T, Nozue N, et al. Effects of 2(3)-tert-butyl-4-hydroxyanisole pretreatment on cefpiramide binding to mouse glutathione S-transferases. Pharmacology. 1989;39(4):213-23. PMID: 2608720.

" Not dangerous goods.

LKT B8070 2-tert-Butyl-4-Hydroxyanisole                          500 mg 289.3 BHA derivative, antioxidative food and cosmetics additive. 2-(1,1-Di-methylethyl)4-methoxyphenol 2-BHA 88-32-4 ≥99% 180.25 C11H16O2 CC(C)(C)C1=C(C=CC(=C1)O)OC Ambient Ambient Insoluble in water. Soluble in ethanol, acetone, or DMSO. "Hwang GH, Jeon YJ, Han HJ, et al. Protective effect of butylated hydroxylanisole against hydrogen peroxide-induced apoptosis in primary cultured mouse hepatocytes. J Vet Sci. 2014 Oct 8. [Epub ahead of print]. PMID: 25293491.

 

Nishiya H, Haga T, Nozue N, et al. Effects of 2(3)-tert-butyl-4-hydroxyanisole pretreatment on cefpiramide binding to mouse glutathione S-transferases. Pharmacology. 1989;39(4):213-23. PMID: 2608720.

" Not dangerous goods.

LKT B8070 2-tert-Butyl-4-Hydroxyanisole                          1 g 452 BHA derivative, antioxidative food and cosmetics additive. 2-(1,1-Di-methylethyl)4-methoxyphenol 2-BHA 88-32-4 ≥99% 180.25 C11H16O2 CC(C)(C)C1=C(C=CC(=C1)O)OC Ambient Ambient Insoluble in water. Soluble in ethanol, acetone, or DMSO. "Hwang GH, Jeon YJ, Han HJ, et al. Protective effect of butylated hydroxylanisole against hydrogen peroxide-induced apoptosis in primary cultured mouse hepatocytes. J Vet Sci. 2014 Oct 8. [Epub ahead of print]. PMID: 25293491.

 

Nishiya H, Haga T, Nozue N, et al. Effects of 2(3)-tert-butyl-4-hydroxyanisole pretreatment on cefpiramide binding to mouse glutathione S-transferases. Pharmacology. 1989;39(4):213-23. PMID: 2608720.

" Not dangerous goods.

LKT B8071 3-tert-Butyl-4-Hydroxyanisole 10 g 197 BHA derivative, antioxidative food and cosmetics additive. 3-(1,1-Di-methylethyl)4-methoxyphenol 3-BHA 121-00-6 ≥99% 180.25 C11H16O2 CC(C)(C)C1=C(C=CC(=C1)OC)O Ambient Ambient Insoluble in water.  Soluble in ethanol, acetone, or DMSO. "Hwang GH, Jeon YJ, Han HJ, et al. Protective effect of butylated hydroxylanisole against hydrogen peroxide-induced apoptosis in primary cultured mouse hepatocytes. J Vet Sci. 2014 Oct 8. [Epub ahead of print]. PMID: 25293491.

 

Okubo T, Yokoyama Y, Kano K, et al. Molecular mechanism of cell death induced by the antioxidant tert-butylhydroxyanisole in human monocytic leukemia U937 cells. Biol Pharm Bull. 2004 Mar;27(3):295-302. PMID: 14993791.

 

Prochaska HJ, Fernandes CL. Elevation of serum phase II enzymes by anticarcinogenic enzyme inducers: markers for a chemoprotected state? Carcinogenesis. 1993 Dec;14(12):2441-5. PMID: 8269610.

 

Matsuoka A, Matsui M, Miyata N, et al. Mutagenicity of 3-tert-butyl-4-hydroxyanisole (BHA) and its metabolites in short-term tests in vitro. Mutat Res. 1990 Jun;241(2):125-32. PMID: 2345551.

" Xi Not dangerous goods.

LKT B8071 3-tert-Butyl-4-Hydroxyanisole 50 g 638.2 BHA derivative, antioxidative food and cosmetics additive. 3-(1,1-Di-methylethyl)4-methoxyphenol 3-BHA 121-00-6 ≥99% 180.25 C11H16O2 CC(C)(C)C1=C(C=CC(=C1)OC)O Ambient Ambient Insoluble in water.  Soluble in ethanol, acetone, or DMSO. "Hwang GH, Jeon YJ, Han HJ, et al. Protective effect of butylated hydroxylanisole against hydrogen peroxide-induced apoptosis in primary cultured mouse hepatocytes. J Vet Sci. 2014 Oct 8. [Epub ahead of print]. PMID: 25293491.

 

Okubo T, Yokoyama Y, Kano K, et al. Molecular mechanism of cell death induced by the antioxidant tert-butylhydroxyanisole in human monocytic leukemia U937 cells. Biol Pharm Bull. 2004 Mar;27(3):295-302. PMID: 14993791.

 

Prochaska HJ, Fernandes CL. Elevation of serum phase II enzymes by anticarcinogenic enzyme inducers: markers for a chemoprotected state? Carcinogenesis. 1993 Dec;14(12):2441-5. PMID: 8269610.

 

Matsuoka A, Matsui M, Miyata N, et al. Mutagenicity of 3-tert-butyl-4-hydroxyanisole (BHA) and its metabolites in short-term tests in vitro. Mutat Res. 1990 Jun;241(2):125-32. PMID: 2345551.

" Xi Not dangerous goods.

LKT B8072 3-tert-Butyl-5-Methoxycatechol 10 mg 112.6 BHA derivative, cellular differentiation inducer. 3-tert-butyl-5-methoxybenzene-1,2-diol 3-(1,1-Dimethylethyl)-5-methoxy-1,2-benzenediol; 3-tert-Butyl-4,5-dihydroxyanisole 80284-15-7 ≥98% 196.25 C11H16O3 CC(C)(C)C1=CC(=CC(=C1O)O)OC Ambient -20°C Partly miscible in Water "Tsuchiya T, Ishida A, Miyata N, et al. Effects of 3-tert-Butyl-4-hydroxyanisole and its hydroquinone and quinone metabolites on rat and human embryonic cells in culture. Toxicol In Vitro. 1988;2(4):291-6. PMID: 20837439.

 

Lam LK, Garg PK, Swanson SM, et al. Evaluation of the cytotoxic potential of catechols and quinones structurally related to butylated hydroxyanisole. J Pharm Sci. 1988 May;77(5):393-5. PMID: 3411459.

" Not dangerous goods.

LKT B8072 3-tert-Butyl-5-Methoxycatechol 50 mg 341.8 BHA derivative, cellular differentiation inducer. 3-tert-butyl-5-methoxybenzene-1,2-diol 3-(1,1-Dimethylethyl)-5-methoxy-1,2-benzenediol; 3-tert-Butyl-4,5-dihydroxyanisole 80284-15-7 ≥98% 196.25 C11H16O3 CC(C)(C)C1=CC(=CC(=C1O)O)OC Ambient -20°C Partly miscible in Water "Tsuchiya T, Ishida A, Miyata N, et al. Effects of 3-tert-Butyl-4-hydroxyanisole and its hydroquinone and quinone metabolites on rat and human embryonic cells in culture. Toxicol In Vitro. 1988;2(4):291-6. PMID: 20837439.

 

Lam LK, Garg PK, Swanson SM, et al. Evaluation of the cytotoxic potential of catechols and quinones structurally related to butylated hydroxyanisole. J Pharm Sci. 1988 May;77(5):393-5. PMID: 3411459.

" Not dangerous goods.

LKT B8072 3-tert-Butyl-5-Methoxycatechol 100 mg 602.5 BHA derivative, cellular differentiation inducer. 3-tert-butyl-5-methoxybenzene-1,2-diol 3-(1,1-Dimethylethyl)-5-methoxy-1,2-benzenediol; 3-tert-Butyl-4,5-dihydroxyanisole 80284-15-7 ≥98% 196.25 C11H16O3 CC(C)(C)C1=CC(=CC(=C1O)O)OC Ambient -20°C Partly miscible in Water "Tsuchiya T, Ishida A, Miyata N, et al. Effects of 3-tert-Butyl-4-hydroxyanisole and its hydroquinone and quinone metabolites on rat and human embryonic cells in culture. Toxicol In Vitro. 1988;2(4):291-6. PMID: 20837439.

 

Lam LK, Garg PK, Swanson SM, et al. Evaluation of the cytotoxic potential of catechols and quinones structurally related to butylated hydroxyanisole. J Pharm Sci. 1988 May;77(5):393-5. PMID: 3411459.

" Not dangerous goods.

LKT B8073 4-tert-Butyl-5-Methoxycatechol 10 mg 129 BHA derivative. 91352-66-8 ≥98% 196.25 C11H16O3 CC(C)(C)C1=CC(=C(C=C1OC)O)O Ambient -20°C Partly miscible in Water Lam LK, Garg PK, Swanson SM, et al. Evaluation of the cytotoxic potential of catechols and quinones structurally related to butylated hydroxyanisole. J Pharm Sci. 1988 May;77(5):393-5. PMID: 3411459. Xi Not dangerous goods.

LKT B8073 4-tert-Butyl-5-Methoxycatechol 50 mg 401.7 BHA derivative. 91352-66-8 ≥98% 196.25 C11H16O3 CC(C)(C)C1=CC(=C(C=C1OC)O)O Ambient -20°C Partly miscible in Water Lam LK, Garg PK, Swanson SM, et al. Evaluation of the cytotoxic potential of catechols and quinones structurally related to butylated hydroxyanisole. J Pharm Sci. 1988 May;77(5):393-5. PMID: 3411459. Xi Not dangerous goods.

LKT B8073 4-tert-Butyl-5-Methoxycatechol 100 mg 702.6 BHA derivative. 91352-66-8 ≥98% 196.25 C11H16O3 CC(C)(C)C1=CC(=C(C=C1OC)O)O Ambient -20°C Partly miscible in Water Lam LK, Garg PK, Swanson SM, et al. Evaluation of the cytotoxic potential of catechols and quinones structurally related to butylated hydroxyanisole. J Pharm Sci. 1988 May;77(5):393-5. PMID: 3411459. Xi Not dangerous goods.

LKT B8074 3-tert-Butyl-5-Methoxy-1,2-quinone 50 mg 181 BHA derivative. 2940-63-8 ≥98% 194.25 C11H14O3 CC(C)(C)C1=CC(=CC(=O)C1=O)OC Ambient -20°C Partly miscible in Water Lam LK, Garg PK, Swanson SM, et al. Evaluation of the cytotoxic potential of catechols and quinones structurally related to butylated hydroxyanisole. J Pharm Sci. 1988 May;77(5):393-5. PMID: 3411459. Not dangerous goods.

LKT B8074 3-tert-Butyl-5-Methoxy-1,2-quinone 100 mg 321.3 BHA derivative. 2940-63-8 ≥98% 194.25 C11H14O3 CC(C)(C)C1=CC(=CC(=O)C1=O)OC Ambient -20°C Partly miscible in Water Lam LK, Garg PK, Swanson SM, et al. Evaluation of the cytotoxic potential of catechols and quinones structurally related to butylated hydroxyanisole. J Pharm Sci. 1988 May;77(5):393-5. PMID: 3411459. Not dangerous goods.

LKT B8074 3-tert-Butyl-5-Methoxy-1,2-quinone 500 mg 1035.7 BHA derivative. 2940-63-8 ≥98% 194.25 C11H14O3 CC(C)(C)C1=CC(=CC(=O)C1=O)OC Ambient -20°C Partly miscible in Water Lam LK, Garg PK, Swanson SM, et al. Evaluation of the cytotoxic potential of catechols and quinones structurally related to butylated hydroxyanisole. J Pharm Sci. 1988 May;77(5):393-5. PMID: 3411459. Not dangerous goods.

LKT B8075 4-tert-Butyl-5-Methoxy-1,2-quinone 50 mg 261.2 BHA derivative. 36122-03-9 ≥98% 194.25 C11H14O3 CC(C)(C)C1=CC(=O)C(=O)C=C1OC Ambient -20°C Lam LK, Garg PK, Swanson SM, et al. Evaluation of the cytotoxic potential of catechols and quinones structurally related to butylated hydroxyanisole. J Pharm Sci. 1988 May;77(5):393-5. PMID: 3411459. Not dangerous goods.

LKT B8075 4-tert-Butyl-5-Methoxy-1,2-quinone 100 mg 462.1 BHA derivative. 36122-03-9 ≥98% 194.25 C11H14O3 CC(C)(C)C1=CC(=O)C(=O)C=C1OC Ambient -20°C Lam LK, Garg PK, Swanson SM, et al. Evaluation of the cytotoxic potential of catechols and quinones structurally related to butylated hydroxyanisole. J Pharm Sci. 1988 May;77(5):393-5. PMID: 3411459. Not dangerous goods.

LKT B8075 4-tert-Butyl-5-Methoxy-1,2-quinone 500 mg 1484.9 BHA derivative. 36122-03-9 ≥98% 194.25 C11H14O3 CC(C)(C)C1=CC(=O)C(=O)C=C1OC Ambient -20°C Lam LK, Garg PK, Swanson SM, et al. Evaluation of the cytotoxic potential of catechols and quinones structurally related to butylated hydroxyanisole. J Pharm Sci. 1988 May;77(5):393-5. PMID: 3411459. Not dangerous goods.

LKT B8176 2-n-Butylthiophene 5 g 100.6 Sulfur analog of furan found in cooked meat products. 1455-20-5 ≥98% 140.25 C8H12S CCCCC1=CC=CS1 Ambient Ambient Soluble in acetone, DMSO or ethanol. Lam LK, Zheng BL. Inhibitory effects of 2-n-heptylfuran and 2-n-butylthiophene on benzo[a]pyrene-induced lung and forestomach tumorigenesis in A/J mice. Nutr Cancer. 1992;17(1):19-26. PMID: 1574441. "UN number: 1993     Class: 3 (F1)     Packing Group: III

Proper shipping name: Flammable liquid, n.o.s. (2-n-Butylthiophene)

"

LKT B8176 2-n-Butylthiophene 10 g 184.8 Sulfur analog of furan found in cooked meat products. 1455-20-5 ≥98% 140.25 C8H12S CCCCC1=CC=CS1 Ambient Ambient Soluble in acetone, DMSO or ethanol. Lam LK, Zheng BL. Inhibitory effects of 2-n-heptylfuran and 2-n-butylthiophene on benzo[a]pyrene-induced lung and forestomach tumorigenesis in A/J mice. Nutr Cancer. 1992;17(1):19-26. PMID: 1574441. "UN number: 1993     Class: 3 (F1)     Packing Group: III

Proper shipping name: Flammable liquid, n.o.s. (2-n-Butylthiophene)

"

LKT C0020 Cafestol 50 mg 220.1 Diterpene found in brewed, unfiltered coffee; FXR and PXR agonist, ERK2 and MEK1 inhibitor. [3b,S-(3bα,5aβ,7β,8β,10aα,10bβ)]-3b,4,5,6,7,8,9,10- 10a,10b,11,12-Dodecahydro-7-hydroxy-10b-methyl- 5a,8-methano-5aH-cyclohepta[5,6]naphtho[2,1-b]furan-7-methanol Cafesterol 469-83-0 ≥98% 316.44 C20H28O3 CC12CCC3=C(C1CCC45C2CCC(C4)C(C5)(CO)O)C=CO3 Ambient -20°C Insoluble in water.  Soluble in DMSO or ethanol to 10 mM, DMF to 12 mg/mL, ethyl acetate or acetone. "Wang S, Yoon YC, Sung MJ, et al. Antiangiogenic properties of cafestol, a coffee diterpene, in human umbilical vein endothelial cells. Biochem Biophys Res Commun. 2012 May 11;421(3):567-71. PMID: 22525673.

 

Choi MJ, Park EJ, Oh JH, et al. Cafestol, a coffee-specific diterpene, induces apoptosis in renal carcinoma Caki cells through down-regulation of anti-apoptotic proteins and Akt phosphorylation. Chem Biol Interact. 2011 Apr 25;190(2-3):102-8. PMID: 21334318.

 

Trinh K, Andrews L, Krause J, et al. Decaffeinated coffee and nicotine-free tobacco provide neuroprotection in Drosophila models of Parkinson's disease through an NRF2-dependent mechanism. J Neurosci. 2010 Apr 21;30(16):5525-32. PMID: 20410106.

 

Shen T, Lee J, Lee E, et al. Cafestol, a coffee-specific diterpene, is a novel extracellular signal-regulated kinase inhibitor with AP-1-targeted inhibition of prostaglandin E2 production in lipopolysaccharide-activated macrophages. Biol Pharm Bull. 2010;33(1):128-32. PMID: 20045950.

 

Ricketts ML, Boekschoten MV, Kreeft AJ, et al. The cholesterol-raising factor from coffee beans, cafestol, as an agonist ligand for the farnesoid and pregnane X receptors. Mol Endocrinol. 2007 Jul;21(7):1603-16. PMID: 17456796.

 

Cavin C, Holzhäuser D, Constable A, et al. The coffee-specific diterpenes cafestol and kahweol protect against aflatoxin B1-induced genotoxicity through a dual mechanism. Carcinogenesis. 1998 Aug;19(8):1369-75. PMID: 9744531.

" Not dangerous goods.

LKT C0020 Cafestol 100 mg 341.8 Diterpene found in brewed, unfiltered coffee; FXR and PXR agonist, ERK2 and MEK1 inhibitor. [3b,S-(3bα,5aβ,7β,8β,10aα,10bβ)]-3b,4,5,6,7,8,9,10- 10a,10b,11,12-Dodecahydro-7-hydroxy-10b-methyl- 5a,8-methano-5aH-cyclohepta[5,6]naphtho[2,1-b]furan-7-methanol Cafesterol 469-83-0 ≥98% 316.44 C20H28O3 CC12CCC3=C(C1CCC45C2CCC(C4)C(C5)(CO)O)C=CO3 Ambient -20°C Insoluble in water.  Soluble in DMSO or ethanol to 10 mM, DMF to 12 mg/mL, ethyl acetate or acetone. "Wang S, Yoon YC, Sung MJ, et al. Antiangiogenic properties of cafestol, a coffee diterpene, in human umbilical vein endothelial cells. Biochem Biophys Res Commun. 2012 May 11;421(3):567-71. PMID: 22525673.

 

Choi MJ, Park EJ, Oh JH, et al. Cafestol, a coffee-specific diterpene, induces apoptosis in renal carcinoma Caki cells through down-regulation of anti-apoptotic proteins and Akt phosphorylation. Chem Biol Interact. 2011 Apr 25;190(2-3):102-8. PMID: 21334318.

 

Trinh K, Andrews L, Krause J, et al. Decaffeinated coffee and nicotine-free tobacco provide neuroprotection in Drosophila models of Parkinson's disease through an NRF2-dependent mechanism. J Neurosci. 2010 Apr 21;30(16):5525-32. PMID: 20410106.

 

Shen T, Lee J, Lee E, et al. Cafestol, a coffee-specific diterpene, is a novel extracellular signal-regulated kinase inhibitor with AP-1-targeted inhibition of prostaglandin E2 production in lipopolysaccharide-activated macrophages. Biol Pharm Bull. 2010;33(1):128-32. PMID: 20045950.

 

Ricketts ML, Boekschoten MV, Kreeft AJ, et al. The cholesterol-raising factor from coffee beans, cafestol, as an agonist ligand for the farnesoid and pregnane X receptors. Mol Endocrinol. 2007 Jul;21(7):1603-16. PMID: 17456796.

 

Cavin C, Holzhäuser D, Constable A, et al. The coffee-specific diterpenes cafestol and kahweol protect against aflatoxin B1-induced genotoxicity through a dual mechanism. Carcinogenesis. 1998 Aug;19(8):1369-75. PMID: 9744531.

" Not dangerous goods.

LKT C0020 Cafestol 500 mg 1204.1 Diterpene found in brewed, unfiltered coffee; FXR and PXR agonist, ERK2 and MEK1 inhibitor. [3b,S-(3bα,5aβ,7β,8β,10aα,10bβ)]-3b,4,5,6,7,8,9,10- 10a,10b,11,12-Dodecahydro-7-hydroxy-10b-methyl- 5a,8-methano-5aH-cyclohepta[5,6]naphtho[2,1-b]furan-7-methanol Cafesterol 469-83-0 ≥98% 316.44 C20H28O3 CC12CCC3=C(C1CCC45C2CCC(C4)C(C5)(CO)O)C=CO3 Ambient -20°C Insoluble in water.  Soluble in DMSO or ethanol to 10 mM, DMF to 12 mg/mL, ethyl acetate or acetone. "Wang S, Yoon YC, Sung MJ, et al. Antiangiogenic properties of cafestol, a coffee diterpene, in human umbilical vein endothelial cells. Biochem Biophys Res Commun. 2012 May 11;421(3):567-71. PMID: 22525673.

 

Choi MJ, Park EJ, Oh JH, et al. Cafestol, a coffee-specific diterpene, induces apoptosis in renal carcinoma Caki cells through down-regulation of anti-apoptotic proteins and Akt phosphorylation. Chem Biol Interact. 2011 Apr 25;190(2-3):102-8. PMID: 21334318.

 

Trinh K, Andrews L, Krause J, et al. Decaffeinated coffee and nicotine-free tobacco provide neuroprotection in Drosophila models of Parkinson's disease through an NRF2-dependent mechanism. J Neurosci. 2010 Apr 21;30(16):5525-32. PMID: 20410106.

 

Shen T, Lee J, Lee E, et al. Cafestol, a coffee-specific diterpene, is a novel extracellular signal-regulated kinase inhibitor with AP-1-targeted inhibition of prostaglandin E2 production in lipopolysaccharide-activated macrophages. Biol Pharm Bull. 2010;33(1):128-32. PMID: 20045950.

 

Ricketts ML, Boekschoten MV, Kreeft AJ, et al. The cholesterol-raising factor from coffee beans, cafestol, as an agonist ligand for the farnesoid and pregnane X receptors. Mol Endocrinol. 2007 Jul;21(7):1603-16. PMID: 17456796.

 

Cavin C, Holzhäuser D, Constable A, et al. The coffee-specific diterpenes cafestol and kahweol protect against aflatoxin B1-induced genotoxicity through a dual mechanism. Carcinogenesis. 1998 Aug;19(8):1369-75. PMID: 9744531.

" Not dangerous goods.

LKT C0021 Cafestol Acetate 50 mg 226.9 Diterpene found in brewed, unfiltered coffee; FXR and PXR agonist, ERK2 and MEK1 inhibitor. [3b,S-(3bα,5aβ,7β,8β,10aα,10bβ)]-3b,4,5,6,7,8,9,10- 10a,10b,11,12-Dodecahydro-7-hydroxy-10b-methyl- 5a,8-methano-5aH-cyclohepta[5,6]naphtho[2,1-b]furan-7-methanol acetate Cafesterol acetate 81760-48-7 ≥98% 358.48 C22H30O4 CC(=O)OCC1(CC23CCC4C5=C(CCC4(C2CCC1C3)C)OC=C5)O Ambient -20°C Insoluble in water.  Soluble in DMSO, ethyl acetate, acetone. "Wang S, Yoon YC, Sung MJ, et al. Antiangiogenic properties of cafestol, a coffee diterpene, in human umbilical vein endothelial cells. Biochem Biophys Res Commun. 2012 May 11;421(3):567-71. PMID: 22525673.

 

Choi MJ, Park EJ, Oh JH, et al. Cafestol, a coffee-specific diterpene, induces apoptosis in renal carcinoma Caki cells through down-regulation of anti-apoptotic proteins and Akt phosphorylation. Chem Biol Interact. 2011 Apr 25;190(2-3):102-8. PMID: 21334318.

 

Trinh K, Andrews L, Krause J, et al. Decaffeinated coffee and nicotine-free tobacco provide neuroprotection in Drosophila models of Parkinson's disease through an NRF2-dependent mechanism. J Neurosci. 2010 Apr 21;30(16):5525-32. PMID: 20410106.

 

Shen T, Lee J, Lee E, et al. Cafestol, a coffee-specific diterpene, is a novel extracellular signal-regulated kinase inhibitor with AP-1-targeted inhibition of prostaglandin E2 production in lipopolysaccharide-activated macrophages. Biol Pharm Bull. 2010;33(1):128-32. PMID: 20045950.

 

Ricketts ML, Boekschoten MV, Kreeft AJ, et al. The cholesterol-raising factor from coffee beans, cafestol, as an agonist ligand for the farnesoid and pregnane X receptors. Mol Endocrinol. 2007 Jul;21(7):1603-16. PMID: 17456796.

 

Cavin C, Holzhäuser D, Constable A, et al. The coffee-specific diterpenes cafestol and kahweol protect against aflatoxin B1-induced genotoxicity through a dual mechanism. Carcinogenesis. 1998 Aug;19(8):1369-75. PMID: 9744531.

" Not dangerous goods.

LKT C0021 Cafestol Acetate 100 mg 361.3 Diterpene found in brewed, unfiltered coffee; FXR and PXR agonist, ERK2 and MEK1 inhibitor. [3b,S-(3bα,5aβ,7β,8β,10aα,10bβ)]-3b,4,5,6,7,8,9,10- 10a,10b,11,12-Dodecahydro-7-hydroxy-10b-methyl- 5a,8-methano-5aH-cyclohepta[5,6]naphtho[2,1-b]furan-7-methanol acetate Cafesterol acetate 81760-48-7 ≥98% 358.48 C22H30O4 CC(=O)OCC1(CC23CCC4C5=C(CCC4(C2CCC1C3)C)OC=C5)O Ambient -20°C Insoluble in water.  Soluble in DMSO, ethyl acetate, acetone. "Wang S, Yoon YC, Sung MJ, et al. Antiangiogenic properties of cafestol, a coffee diterpene, in human umbilical vein endothelial cells. Biochem Biophys Res Commun. 2012 May 11;421(3):567-71. PMID: 22525673.

 

Choi MJ, Park EJ, Oh JH, et al. Cafestol, a coffee-specific diterpene, induces apoptosis in renal carcinoma Caki cells through down-regulation of anti-apoptotic proteins and Akt phosphorylation. Chem Biol Interact. 2011 Apr 25;190(2-3):102-8. PMID: 21334318.

 

Trinh K, Andrews L, Krause J, et al. Decaffeinated coffee and nicotine-free tobacco provide neuroprotection in Drosophila models of Parkinson's disease through an NRF2-dependent mechanism. J Neurosci. 2010 Apr 21;30(16):5525-32. PMID: 20410106.

 

Shen T, Lee J, Lee E, et al. Cafestol, a coffee-specific diterpene, is a novel extracellular signal-regulated kinase inhibitor with AP-1-targeted inhibition of prostaglandin E2 production in lipopolysaccharide-activated macrophages. Biol Pharm Bull. 2010;33(1):128-32. PMID: 20045950.

 

Ricketts ML, Boekschoten MV, Kreeft AJ, et al. The cholesterol-raising factor from coffee beans, cafestol, as an agonist ligand for the farnesoid and pregnane X receptors. Mol Endocrinol. 2007 Jul;21(7):1603-16. PMID: 17456796.

 

Cavin C, Holzhäuser D, Constable A, et al. The coffee-specific diterpenes cafestol and kahweol protect against aflatoxin B1-induced genotoxicity through a dual mechanism. Carcinogenesis. 1998 Aug;19(8):1369-75. PMID: 9744531.

" Not dangerous goods.

LKT C0021 Cafestol Acetate 500 mg 1244.9 Diterpene found in brewed, unfiltered coffee; FXR and PXR agonist, ERK2 and MEK1 inhibitor. [3b,S-(3bα,5aβ,7β,8β,10aα,10bβ)]-3b,4,5,6,7,8,9,10- 10a,10b,11,12-Dodecahydro-7-hydroxy-10b-methyl- 5a,8-methano-5aH-cyclohepta[5,6]naphtho[2,1-b]furan-7-methanol acetate Cafesterol acetate 81760-48-7 ≥98% 358.48 C22H30O4 CC(=O)OCC1(CC23CCC4C5=C(CCC4(C2CCC1C3)C)OC=C5)O Ambient -20°C Insoluble in water.  Soluble in DMSO, ethyl acetate, acetone. "Wang S, Yoon YC, Sung MJ, et al. Antiangiogenic properties of cafestol, a coffee diterpene, in human umbilical vein endothelial cells. Biochem Biophys Res Commun. 2012 May 11;421(3):567-71. PMID: 22525673.

 

Choi MJ, Park EJ, Oh JH, et al. Cafestol, a coffee-specific diterpene, induces apoptosis in renal carcinoma Caki cells through down-regulation of anti-apoptotic proteins and Akt phosphorylation. Chem Biol Interact. 2011 Apr 25;190(2-3):102-8. PMID: 21334318.

 

Trinh K, Andrews L, Krause J, et al. Decaffeinated coffee and nicotine-free tobacco provide neuroprotection in Drosophila models of Parkinson's disease through an NRF2-dependent mechanism. J Neurosci. 2010 Apr 21;30(16):5525-32. PMID: 20410106.

 

Shen T, Lee J, Lee E, et al. Cafestol, a coffee-specific diterpene, is a novel extracellular signal-regulated kinase inhibitor with AP-1-targeted inhibition of prostaglandin E2 production in lipopolysaccharide-activated macrophages. Biol Pharm Bull. 2010;33(1):128-32. PMID: 20045950.

 

Ricketts ML, Boekschoten MV, Kreeft AJ, et al. The cholesterol-raising factor from coffee beans, cafestol, as an agonist ligand for the farnesoid and pregnane X receptors. Mol Endocrinol. 2007 Jul;21(7):1603-16. PMID: 17456796.

 

Cavin C, Holzhäuser D, Constable A, et al. The coffee-specific diterpenes cafestol and kahweol protect against aflatoxin B1-induced genotoxicity through a dual mechanism. Carcinogenesis. 1998 Aug;19(8):1369-75. PMID: 9744531.

" Not dangerous goods.

LKT C0022 Cafestol Palmitate 50 mg 231.4 Diterpene found in brewed, unfiltered coffee; FXR and PXR agonist, ERK2 and MEK1 inhibitor. [3b,S-(3bα,5aβ,7β,8β,10aα,10bβ)]-3b,4,5,6,7,8,9,10- 10a,10b,11,12-Dodecahydro-7-hydroxy-10b-methyl- 5a,8-methano-5aH-cyclohepta[5,6]naphtho[2,1-b]furan-7-methanol palmitate Cafesterol palmitate 81760-46-5 ≥98% 554.43 C36H58O4 CCCCCCCCCCCCCCCC(=O)OCC1(CC23CCC4C5=C(CCC4(C2CCC1C3)C)OC=C5)O Ambient -20°C "Wang S, Yoon YC, Sung MJ, et al. Antiangiogenic properties of cafestol, a coffee diterpene, in human umbilical vein endothelial cells. Biochem Biophys Res Commun. 2012 May 11;421(3):567-71. PMID: 22525673.

 

Choi MJ, Park EJ, Oh JH, et al. Cafestol, a coffee-specific diterpene, induces apoptosis in renal carcinoma Caki cells through down-regulation of anti-apoptotic proteins and Akt phosphorylation. Chem Biol Interact. 2011 Apr 25;190(2-3):102-8. PMID: 21334318.

 

Trinh K, Andrews L, Krause J, et al. Decaffeinated coffee and nicotine-free tobacco provide neuroprotection in Drosophila models of Parkinson's disease through an NRF2-dependent mechanism. J Neurosci. 2010 Apr 21;30(16):5525-32. PMID: 20410106.

 

Shen T, Lee J, Lee E, et al. Cafestol, a coffee-specific diterpene, is a novel extracellular signal-regulated kinase inhibitor with AP-1-targeted inhibition of prostaglandin E2 production in lipopolysaccharide-activated macrophages. Biol Pharm Bull. 2010;33(1):128-32. PMID: 20045950.

 

Ricketts ML, Boekschoten MV, Kreeft AJ, et al. The cholesterol-raising factor from coffee beans, cafestol, as an agonist ligand for the farnesoid and pregnane X receptors. Mol Endocrinol. 2007 Jul;21(7):1603-16. PMID: 17456796.

 

Cavin C, Holzhäuser D, Constable A, et al. The coffee-specific diterpenes cafestol and kahweol protect against aflatoxin B1-induced genotoxicity through a dual mechanism. Carcinogenesis. 1998 Aug;19(8):1369-75. PMID: 9744531.

" Not dangerous goods.

LKT C0022 Cafestol Palmitate 100 mg 361.3 Diterpene found in brewed, unfiltered coffee; FXR and PXR agonist, ERK2 and MEK1 inhibitor. [3b,S-(3bα,5aβ,7β,8β,10aα,10bβ)]-3b,4,5,6,7,8,9,10- 10a,10b,11,12-Dodecahydro-7-hydroxy-10b-methyl- 5a,8-methano-5aH-cyclohepta[5,6]naphtho[2,1-b]furan-7-methanol palmitate Cafesterol palmitate 81760-46-5 ≥98% 554.43 C36H58O4 CCCCCCCCCCCCCCCC(=O)OCC1(CC23CCC4C5=C(CCC4(C2CCC1C3)C)OC=C5)O Ambient -20°C "Wang S, Yoon YC, Sung MJ, et al. Antiangiogenic properties of cafestol, a coffee diterpene, in human umbilical vein endothelial cells. Biochem Biophys Res Commun. 2012 May 11;421(3):567-71. PMID: 22525673.

 

Choi MJ, Park EJ, Oh JH, et al. Cafestol, a coffee-specific diterpene, induces apoptosis in renal carcinoma Caki cells through down-regulation of anti-apoptotic proteins and Akt phosphorylation. Chem Biol Interact. 2011 Apr 25;190(2-3):102-8. PMID: 21334318.

 

Trinh K, Andrews L, Krause J, et al. Decaffeinated coffee and nicotine-free tobacco provide neuroprotection in Drosophila models of Parkinson's disease through an NRF2-dependent mechanism. J Neurosci. 2010 Apr 21;30(16):5525-32. PMID: 20410106.

 

Shen T, Lee J, Lee E, et al. Cafestol, a coffee-specific diterpene, is a novel extracellular signal-regulated kinase inhibitor with AP-1-targeted inhibition of prostaglandin E2 production in lipopolysaccharide-activated macrophages. Biol Pharm Bull. 2010;33(1):128-32. PMID: 20045950.

 

Ricketts ML, Boekschoten MV, Kreeft AJ, et al. The cholesterol-raising factor from coffee beans, cafestol, as an agonist ligand for the farnesoid and pregnane X receptors. Mol Endocrinol. 2007 Jul;21(7):1603-16. PMID: 17456796.

 

Cavin C, Holzhäuser D, Constable A, et al. The coffee-specific diterpenes cafestol and kahweol protect against aflatoxin B1-induced genotoxicity through a dual mechanism. Carcinogenesis. 1998 Aug;19(8):1369-75. PMID: 9744531.

" Not dangerous goods.

LKT C0022 Cafestol Palmitate 500 mg 1244.9 Diterpene found in brewed, unfiltered coffee; FXR and PXR agonist, ERK2 and MEK1 inhibitor. [3b,S-(3bα,5aβ,7β,8β,10aα,10bβ)]-3b,4,5,6,7,8,9,10- 10a,10b,11,12-Dodecahydro-7-hydroxy-10b-methyl- 5a,8-methano-5aH-cyclohepta[5,6]naphtho[2,1-b]furan-7-methanol palmitate Cafesterol palmitate 81760-46-5 ≥98% 554.43 C36H58O4 CCCCCCCCCCCCCCCC(=O)OCC1(CC23CCC4C5=C(CCC4(C2CCC1C3)C)OC=C5)O Ambient -20°C "Wang S, Yoon YC, Sung MJ, et al. Antiangiogenic properties of cafestol, a coffee diterpene, in human umbilical vein endothelial cells. Biochem Biophys Res Commun. 2012 May 11;421(3):567-71. PMID: 22525673.

 

Choi MJ, Park EJ, Oh JH, et al. Cafestol, a coffee-specific diterpene, induces apoptosis in renal carcinoma Caki cells through down-regulation of anti-apoptotic proteins and Akt phosphorylation. Chem Biol Interact. 2011 Apr 25;190(2-3):102-8. PMID: 21334318.

 

Trinh K, Andrews L, Krause J, et al. Decaffeinated coffee and nicotine-free tobacco provide neuroprotection in Drosophila models of Parkinson's disease through an NRF2-dependent mechanism. J Neurosci. 2010 Apr 21;30(16):5525-32. PMID: 20410106.

 

Shen T, Lee J, Lee E, et al. Cafestol, a coffee-specific diterpene, is a novel extracellular signal-regulated kinase inhibitor with AP-1-targeted inhibition of prostaglandin E2 production in lipopolysaccharide-activated macrophages. Biol Pharm Bull. 2010;33(1):128-32. PMID: 20045950.

 

Ricketts ML, Boekschoten MV, Kreeft AJ, et al. The cholesterol-raising factor from coffee beans, cafestol, as an agonist ligand for the farnesoid and pregnane X receptors. Mol Endocrinol. 2007 Jul;21(7):1603-16. PMID: 17456796.

 

Cavin C, Holzhäuser D, Constable A, et al. The coffee-specific diterpenes cafestol and kahweol protect against aflatoxin B1-induced genotoxicity through a dual mechanism. Carcinogenesis. 1998 Aug;19(8):1369-75. PMID: 9744531.

" Not dangerous goods.

LKT C0121 Caffeic Acid 5 g 41.4 Hydroxycinnamic acid found in coffee, argan oil, Eucaplyptus, Salvinia, and Phellinus; α-amylase and α-glucosidase inhibitor. 3-(3,4-Dihydroxyphenyl)-2-propenoic acid 3,4-Dihydroxycinnamic acid 331-39-5 ≥98% 180.16 C9H8O4 C1=CC(=C(C=C1C=CC(=O)O)O)O Ambient Ambient Sparingly soluble in water.  Soluble in DMSO. "Oboh G, Agunloye OM, Adefegha SA, et al. Caffeic and chlorogenic acids inhibit key enzymes linked to type 2 diabetes (in vitro): a comparative study. J Basic Clin Physiol Pharmacol. 2014 May 12. [Epub ahead of print]. PMID: 24825096.

 

Liu M, Song S, Li H, et al. The protective effect of caffeic acid against inflammation injury of primary bovine mammary epithelial cells induced by lipopolysaccharide. J Dairy Sci. 2014 May;97(5):2856-65. PMID: 24612802.

 

Luís Â, Silva F, Sousa S, et al. Antistaphylococcal and biofilm inhibitory activities of gallic, caffeic, and chlorogenic acids. Biofouling. 2014 Jan;30(1):69-79. PMID: 24228999.

 

Tsai CM, Yen GC, Sun FM, et al. Assessment of the anti-invasion potential and mechanism of select cinnamic acid derivatives on human lung adenocarcinoma cells. Mol Pharm. 2013 May 6;10(5):1890-900. PMID: 23560439.

 

Jaganathan SK. Growth inhibition by caffeic acid, one of the phenolic constituents of honey, in HCT 15 colon cancer cells. ScientificWorldJournal. 2012;2012:372345. PMID: 22649289.

 

Pluemsamran T, Onkoksoong T, Panich U. Caffeic acid and ferulic acid inhibit UVA-induced matrix metalloproteinase-1 through regulation of antioxidant defense system in keratinocyte HaCaT cells. Photochem Photobiol. 2012 Jul-Aug;88(4):961-8. PMID: 22360712.

" Carc., Xi Not dangerous goods.

LKT C0121 Caffeic Acid 25 g 116.5 Hydroxycinnamic acid found in coffee, argan oil, Eucaplyptus, Salvinia, and Phellinus; α-amylase and α-glucosidase inhibitor. 3-(3,4-Dihydroxyphenyl)-2-propenoic acid 3,4-Dihydroxycinnamic acid 331-39-5 ≥98% 180.16 C9H8O4 C1=CC(=C(C=C1C=CC(=O)O)O)O Ambient Ambient Sparingly soluble in water.  Soluble in DMSO. "Oboh G, Agunloye OM, Adefegha SA, et al. Caffeic and chlorogenic acids inhibit key enzymes linked to type 2 diabetes (in vitro): a comparative study. J Basic Clin Physiol Pharmacol. 2014 May 12. [Epub ahead of print]. PMID: 24825096.

 

Liu M, Song S, Li H, et al. The protective effect of caffeic acid against inflammation injury of primary bovine mammary epithelial cells induced by lipopolysaccharide. J Dairy Sci. 2014 May;97(5):2856-65. PMID: 24612802.

 

Luís Â, Silva F, Sousa S, et al. Antistaphylococcal and biofilm inhibitory activities of gallic, caffeic, and chlorogenic acids. Biofouling. 2014 Jan;30(1):69-79. PMID: 24228999.

 

Tsai CM, Yen GC, Sun FM, et al. Assessment of the anti-invasion potential and mechanism of select cinnamic acid derivatives on human lung adenocarcinoma cells. Mol Pharm. 2013 May 6;10(5):1890-900. PMID: 23560439.

 

Jaganathan SK. Growth inhibition by caffeic acid, one of the phenolic constituents of honey, in HCT 15 colon cancer cells. ScientificWorldJournal. 2012;2012:372345. PMID: 22649289.

 

Pluemsamran T, Onkoksoong T, Panich U. Caffeic acid and ferulic acid inhibit UVA-induced matrix metalloproteinase-1 through regulation of antioxidant defense system in keratinocyte HaCaT cells. Photochem Photobiol. 2012 Jul-Aug;88(4):961-8. PMID: 22360712.

" Carc., Xi Not dangerous goods.

LKT C0145 Calcitriol 50 µg 197.7 Active form of vitamin D, regulates dietary Ca2+ absorption; VDR agonist. (1α,3β,5Z,7E)-9,10-Secocholesta-5,710(19)-triene-1,3,25-triol 1α,25-Dihydroxyvitamin D3 32222-06-3 ≥97% 416.64 C27H44O3 CC(CCCC(C)(C)O)C1CCC2C1(CCCC2=CC=C3CC(CC(C3=C)O)O)C Air, light and moisture sensitive. Dry Ice -80°C Slightly soluble in ethanol, ethyl acetate. Soluble in DMSO "Albert B, Hahn H. Interaction of hedgehog and vitamin D signaling pathways in basal cell carcinomas. Adv Exp Med Biol. 2014;810:329-41. PMID: 25207374.

 

Bikle DD. The vitamin D receptor: a tumor suppressor in skin. Adv Exp Med Biol. 2014;810:282-302. PMID: 25207372.

 

Adamczak DM, Nowak JK, Frydrychowicz M, et al. The role of Toll-like receptors and vitamin D in diabetes mellitus type 1--a review. Scand J Immunol. 2014 Aug;80(2):75-84. PMID: 24845558.

 

Vojinovic J. Vitamin D receptor agonists' anti-inflammatory properties. Ann N Y Acad Sci. 2014 May;1317:47-56. PMID: 24754474.

" T+ "UN number: 2811    Class:  6.1     Packing group:  I

Proper shipping name:  Toxic solids, organic, n.o.s. (Calcitriol)

Reportable quantity (RQ):     Marine pollutant:  No     Poison inhalation hazard:  No"

LKT C0145 Calcitriol 5 x 50 µg 593.2 Active form of vitamin D, regulates dietary Ca2+ absorption; VDR agonist. (1α,3β,5Z,7E)-9,10-Secocholesta-5,710(19)-triene-1,3,25-triol 1α,25-Dihydroxyvitamin D3 32222-06-3 ≥97% 416.64 C27H44O3 CC(CCCC(C)(C)O)C1CCC2C1(CCCC2=CC=C3CC(CC(C3=C)O)O)C Air, light and moisture sensitive. Dry Ice -80°C Slightly soluble in ethanol, ethyl acetate. Soluble in DMSO "Albert B, Hahn H. Interaction of hedgehog and vitamin D signaling pathways in basal cell carcinomas. Adv Exp Med Biol. 2014;810:329-41. PMID: 25207374.

 

Bikle DD. The vitamin D receptor: a tumor suppressor in skin. Adv Exp Med Biol. 2014;810:282-302. PMID: 25207372.

 

Adamczak DM, Nowak JK, Frydrychowicz M, et al. The role of Toll-like receptors and vitamin D in diabetes mellitus type 1--a review. Scand J Immunol. 2014 Aug;80(2):75-84. PMID: 24845558.

 

Vojinovic J. Vitamin D receptor agonists' anti-inflammatory properties. Ann N Y Acad Sci. 2014 May;1317:47-56. PMID: 24754474.

" T+ "UN number: 2811    Class:  6.1     Packing group:  I

Proper shipping name:  Toxic solids, organic, n.o.s. (Calcitriol)

Reportable quantity (RQ):     Marine pollutant:  No     Poison inhalation hazard:  No"

LKT C0145 Calcitriol 1 mg 632.8 Active form of vitamin D, regulates dietary Ca2+ absorption; VDR agonist. (1α,3β,5Z,7E)-9,10-Secocholesta-5,710(19)-triene-1,3,25-triol 1α,25-Dihydroxyvitamin D3 32222-06-3 ≥97% 416.64 C27H44O3 CC(CCCC(C)(C)O)C1CCC2C1(CCCC2=CC=C3CC(CC(C3=C)O)O)C Air, light and moisture sensitive. Dry Ice -80°C Slightly soluble in ethanol, ethyl acetate. Soluble in DMSO "Albert B, Hahn H. Interaction of hedgehog and vitamin D signaling pathways in basal cell carcinomas. Adv Exp Med Biol. 2014;810:329-41. PMID: 25207374.

 

Bikle DD. The vitamin D receptor: a tumor suppressor in skin. Adv Exp Med Biol. 2014;810:282-302. PMID: 25207372.

 

Adamczak DM, Nowak JK, Frydrychowicz M, et al. The role of Toll-like receptors and vitamin D in diabetes mellitus type 1--a review. Scand J Immunol. 2014 Aug;80(2):75-84. PMID: 24845558.

 

Vojinovic J. Vitamin D receptor agonists' anti-inflammatory properties. Ann N Y Acad Sci. 2014 May;1317:47-56. PMID: 24754474.

" T+ "UN number: 2811    Class:  6.1     Packing group:  I

Proper shipping name:  Toxic solids, organic, n.o.s. (Calcitriol)

Reportable quantity (RQ):     Marine pollutant:  No     Poison inhalation hazard:  No"

LKT C0147 Calcium Folinate Pentahydrate 100 mg 64.6 Folate source co-administered with methotrexate; potential thymidylate synthase inhibitor. N-[4-[[(2-Amino-5-formyl-1,4,5,6,7,8-hexahydro-4- oxo-6-pteridinyl)methyl]-amino]benzoyl]-L-glutamic acid calcium salt pentahydrate Leucovorin; 5-Formyl-5,6,7,8-tetrahydrofolic acid, calcium salt 6035-45-6 ≥95% 601.59 C20H21CaN7O7.5H2O C1C(N(C2=C(N1)NC(=NC2=O)N)C=O)CNC3=CC=C(C=C3)C(=O)NC(CCC(=O)[O-])C(=O)[O-].O.O.O.O.O.[Ca+2] Ambient 4°C Soluble in water.  Insoluble in ethanol "Chen C, Tian L, Zhang M, et al. Protective effect of amifostine on high-dose methotrexate-induced small intestinal mucositis in mice. Dig Dis Sci. 2013 Nov;58(11):3134-43. PMID: 23979434.

 

Payet B, Fabre G, Tubiana N, et al. Plasma kinetic study of folinic acid and 5-methyltetrahydrofolate in healthy volunteers and cancer patients by high-performance liquid chromatography. Cancer Chemother Pharmacol. 1987;19(4):319-25. PMID: 3496173.

" Xi Not dangerous goods.

LKT C0147 Calcium Folinate Pentahydrate 500 mg 272.6 Folate source co-administered with methotrexate; potential thymidylate synthase inhibitor. N-[4-[[(2-Amino-5-formyl-1,4,5,6,7,8-hexahydro-4- oxo-6-pteridinyl)methyl]-amino]benzoyl]-L-glutamic acid calcium salt pentahydrate Leucovorin; 5-Formyl-5,6,7,8-tetrahydrofolic acid, calcium salt 6035-45-6 ≥95% 601.59 C20H21CaN7O7.5H2O C1C(N(C2=C(N1)NC(=NC2=O)N)C=O)CNC3=CC=C(C=C3)C(=O)NC(CCC(=O)[O-])C(=O)[O-].O.O.O.O.O.[Ca+2] Ambient 4°C Soluble in water.  Insoluble in ethanol "Chen C, Tian L, Zhang M, et al. Protective effect of amifostine on high-dose methotrexate-induced small intestinal mucositis in mice. Dig Dis Sci. 2013 Nov;58(11):3134-43. PMID: 23979434.

 

Payet B, Fabre G, Tubiana N, et al. Plasma kinetic study of folinic acid and 5-methyltetrahydrofolate in healthy volunteers and cancer patients by high-performance liquid chromatography. Cancer Chemother Pharmacol. 1987;19(4):319-25. PMID: 3496173.

" Xi Not dangerous goods.

LKT C0147 Calcium Folinate Pentahydrate 1 g 457.6 Folate source co-administered with methotrexate; potential thymidylate synthase inhibitor. N-[4-[[(2-Amino-5-formyl-1,4,5,6,7,8-hexahydro-4- oxo-6-pteridinyl)methyl]-amino]benzoyl]-L-glutamic acid calcium salt pentahydrate Leucovorin; 5-Formyl-5,6,7,8-tetrahydrofolic acid, calcium salt 6035-45-6 ≥95% 601.59 C20H21CaN7O7.5H2O C1C(N(C2=C(N1)NC(=NC2=O)N)C=O)CNC3=CC=C(C=C3)C(=O)NC(CCC(=O)[O-])C(=O)[O-].O.O.O.O.O.[Ca+2] Ambient 4°C Soluble in water.  Insoluble in ethanol "Chen C, Tian L, Zhang M, et al. Protective effect of amifostine on high-dose methotrexate-induced small intestinal mucositis in mice. Dig Dis Sci. 2013 Nov;58(11):3134-43. PMID: 23979434.

 

Payet B, Fabre G, Tubiana N, et al. Plasma kinetic study of folinic acid and 5-methyltetrahydrofolate in healthy volunteers and cancer patients by high-performance liquid chromatography. Cancer Chemother Pharmacol. 1987;19(4):319-25. PMID: 3496173.

" Xi Not dangerous goods.

LKT C0150 Camptothecin 25 mg 27.2 Quinolone alkaloid precursor of irinotecan, originally found in Camptotheca; topoisomerase I inhibitor. (S)-4-Ethyl-4-hydroxy-1H-pyrano[3',4':6,7]indolizino- [1,2-b]quinoline-3,14(4H,12H)-dione 7689-03-4 ≥98% 348.35 C20H16N2O4 CCC1(C2=C(COC1=O)C(=O)N3CC4=CC5=CC=CC=C5N=C4C3=C2)O Ambient -20°C Soluble in DMSO. "Rodríguez-Berna G, Mangas-Sanjuán V, Gonzalez-Alvarez M, et al. A promising camptothecin derivative: Semisynthesis, antitumor activity and intestinal permeability. Eur J Med Chem. 2014 Jun 25;83C:366-373. PMID: 24980118.

 

Berniak K, Rybak P, Bernas T, et al. Relationship between DNA damage response, initiated by camptothecin or oxidative stress, and DNA replication, analyzed by quantitative 3D image analysis. Cytometry A. 2013 Jul 11. [Epub ahead of print]. PMID: 23846844.

 

Redinbo MR, Stewart L, Kuhn P, et al. Crystal structures of human topoisomerase I in covalent and noncovalent complexes with DNA. Science. 1998 Mar 6;279(5356):1504-13. PMID: 9488644.

" T "UN number: 1544     Class: 6.1     Packing group:  III

Proper shipping name:  Alkaloids, solid, n.o.s. ((S)-(+)-Camptothecin)

Marine pollutant:  No.     Poison Inhalation Hazard:  No"

LKT C0150 Camptothecin 100 mg 54.4 Quinolone alkaloid precursor of irinotecan, originally found in Camptotheca; topoisomerase I inhibitor. (S)-4-Ethyl-4-hydroxy-1H-pyrano[3',4':6,7]indolizino- [1,2-b]quinoline-3,14(4H,12H)-dione 7689-03-4 ≥98% 348.35 C20H16N2O4 CCC1(C2=C(COC1=O)C(=O)N3CC4=CC5=CC=CC=C5N=C4C3=C2)O Ambient -20°C Soluble in DMSO. "Rodríguez-Berna G, Mangas-Sanjuán V, Gonzalez-Alvarez M, et al. A promising camptothecin derivative: Semisynthesis, antitumor activity and intestinal permeability. Eur J Med Chem. 2014 Jun 25;83C:366-373. PMID: 24980118.

 

Berniak K, Rybak P, Bernas T, et al. Relationship between DNA damage response, initiated by camptothecin or oxidative stress, and DNA replication, analyzed by quantitative 3D image analysis. Cytometry A. 2013 Jul 11. [Epub ahead of print]. PMID: 23846844.

 

Redinbo MR, Stewart L, Kuhn P, et al. Crystal structures of human topoisomerase I in covalent and noncovalent complexes with DNA. Science. 1998 Mar 6;279(5356):1504-13. PMID: 9488644.

" T "UN number: 1544     Class: 6.1     Packing group:  III

Proper shipping name:  Alkaloids, solid, n.o.s. ((S)-(+)-Camptothecin)

Marine pollutant:  No.     Poison Inhalation Hazard:  No"

LKT C0150 Camptothecin 250 mg 133.5 Quinolone alkaloid precursor of irinotecan, originally found in Camptotheca; topoisomerase I inhibitor. (S)-4-Ethyl-4-hydroxy-1H-pyrano[3',4':6,7]indolizino- [1,2-b]quinoline-3,14(4H,12H)-dione 7689-03-4 ≥98% 348.35 C20H16N2O4 CCC1(C2=C(COC1=O)C(=O)N3CC4=CC5=CC=CC=C5N=C4C3=C2)O Ambient -20°C Soluble in DMSO. "Rodríguez-Berna G, Mangas-Sanjuán V, Gonzalez-Alvarez M, et al. A promising camptothecin derivative: Semisynthesis, antitumor activity and intestinal permeability. Eur J Med Chem. 2014 Jun 25;83C:366-373. PMID: 24980118.

 

Berniak K, Rybak P, Bernas T, et al. Relationship between DNA damage response, initiated by camptothecin or oxidative stress, and DNA replication, analyzed by quantitative 3D image analysis. Cytometry A. 2013 Jul 11. [Epub ahead of print]. PMID: 23846844.

 

Redinbo MR, Stewart L, Kuhn P, et al. Crystal structures of human topoisomerase I in covalent and noncovalent complexes with DNA. Science. 1998 Mar 6;279(5356):1504-13. PMID: 9488644.

" T "UN number: 1544     Class: 6.1     Packing group:  III

Proper shipping name:  Alkaloids, solid, n.o.s. ((S)-(+)-Camptothecin)

Marine pollutant:  No.     Poison Inhalation Hazard:  No"

LKT C0155 10-Hydroxycamptothecin 25 mg 78.2 Camptothecin derivative; topoisomerase I inhibitor. (S)-4-Ethyl-4,10-dihydroxy-1H-pyrano[3',4':6,7]indolizino[1,2-b]quinoline-3,14(4H,12H)-dione 19685-09-7 ≥96% 364.35 C20H16N2O5 CCC1(C2=C(COC1=O)C(=O)N3CC4=C(C3=C2)N=C5C=CC(=CC5=C4)O)O Ambient -20°C Soluble in DMSO. "Rodríguez-Berna G, Mangas-Sanjuán V, Gonzalez-Alvarez M, et al. A promising camptothecin derivative: Semisynthesis, antitumor activity and intestinal permeability. Eur J Med Chem. 2014 Jun 25;83C:366-373. PMID: 24980118.

 

Berniak K, Rybak P, Bernas T, et al. Relationship between DNA damage response, initiated by camptothecin or oxidative stress, and DNA replication, analyzed by quantitative 3D image analysis. Cytometry A. 2013 Jul 11. [Epub ahead of print]. PMID: 23846844.

 

Redinbo MR, Stewart L, Kuhn P, et al. Crystal structures of human topoisomerase I in covalent and noncovalent complexes with DNA. Science. 1998 Mar 6;279(5356):1504-13. PMID: 9488644.

" Xi Not dangerous goods.

LKT C0155 10-Hydroxycamptothecin 100 mg 218.5 Camptothecin derivative; topoisomerase I inhibitor. (S)-4-Ethyl-4,10-dihydroxy-1H-pyrano[3',4':6,7]indolizino[1,2-b]quinoline-3,14(4H,12H)-dione 19685-09-7 ≥96% 364.35 C20H16N2O5 CCC1(C2=C(COC1=O)C(=O)N3CC4=C(C3=C2)N=C5C=CC(=CC5=C4)O)O Ambient -20°C Soluble in DMSO. "Rodríguez-Berna G, Mangas-Sanjuán V, Gonzalez-Alvarez M, et al. A promising camptothecin derivative: Semisynthesis, antitumor activity and intestinal permeability. Eur J Med Chem. 2014 Jun 25;83C:366-373. PMID: 24980118.

 

Berniak K, Rybak P, Bernas T, et al. Relationship between DNA damage response, initiated by camptothecin or oxidative stress, and DNA replication, analyzed by quantitative 3D image analysis. Cytometry A. 2013 Jul 11. [Epub ahead of print]. PMID: 23846844.

 

Redinbo MR, Stewart L, Kuhn P, et al. Crystal structures of human topoisomerase I in covalent and noncovalent complexes with DNA. Science. 1998 Mar 6;279(5356):1504-13. PMID: 9488644.

" Xi Not dangerous goods.

LKT C0168 Canthaxanthin 5 g 79.1 Carotenoid terpene pigment found in various plant sources. β,β-Carotene-4,4'-dione 514-78-3 ≥9% 564.84 C40H52O2 CC1=C(C(CCC1=O)(C)C)C=CC(=CC=CC(=CC=CC=C(C)C=CC=C(C)C=CC2=C(C(=O)CCC2(C)C)C)C)C Ambient Ambient Soluble in chloroform or oil. Slightly soluble in methanol.  "Chew BP, Park JS. Carotenoid action on the immune response. J Nutr. 2004 Jan;134(1):257S-261S. PMID: 14704330.

 

Stahl W, Sies H. The role of carotenoids and retinoids in gap junctional communication. Int J Vitam Nutr Res. 1998;68(6):354-9. PMID: 9857261.

 

Palozza P, Luberto C, Ricci P, et al. Effect of beta-carotene and canthaxanthin on tert-butyl hydroperoxide-induced lipid peroxidation in murine normal and tumor thymocytes. Arch Biochem Biophys. 1996 Jan 15;325(2):145-51. PMID: 8561491.

 

Pung A, Rundhaug JE, Yoshizawa CN, et al. Beta-carotene and canthaxanthin inhibit chemically- and physically-induced neoplastic transformation in 10T1/2 cells. Carcinogenesis. 1988 Sep;9(9):1533-9. PMID: 3136943.

" Not dangerous goods.

LKT C0168 Canthaxanthin 10 g 99.6 Carotenoid terpene pigment found in various plant sources. β,β-Carotene-4,4'-dione 514-78-3 ≥9% 564.84 C40H52O2 CC1=C(C(CCC1=O)(C)C)C=CC(=CC=CC(=CC=CC=C(C)C=CC=C(C)C=CC2=C(C(=O)CCC2(C)C)C)C)C Ambient Ambient Soluble in chloroform or oil. Slightly soluble in methanol.  "Chew BP, Park JS. Carotenoid action on the immune response. J Nutr. 2004 Jan;134(1):257S-261S. PMID: 14704330.

 

Stahl W, Sies H. The role of carotenoids and retinoids in gap junctional communication. Int J Vitam Nutr Res. 1998;68(6):354-9. PMID: 9857261.

 

Palozza P, Luberto C, Ricci P, et al. Effect of beta-carotene and canthaxanthin on tert-butyl hydroperoxide-induced lipid peroxidation in murine normal and tumor thymocytes. Arch Biochem Biophys. 1996 Jan 15;325(2):145-51. PMID: 8561491.

 

Pung A, Rundhaug JE, Yoshizawa CN, et al. Beta-carotene and canthaxanthin inhibit chemically- and physically-induced neoplastic transformation in 10T1/2 cells. Carcinogenesis. 1988 Sep;9(9):1533-9. PMID: 3136943.

" Not dangerous goods.

LKT C0168 Canthaxanthin 25 g 163.8 Carotenoid terpene pigment found in various plant sources. β,β-Carotene-4,4'-dione 514-78-3 ≥9% 564.84 C40H52O2 CC1=C(C(CCC1=O)(C)C)C=CC(=CC=CC(=CC=CC=C(C)C=CC=C(C)C=CC2=C(C(=O)CCC2(C)C)C)C)C Ambient Ambient Soluble in chloroform or oil. Slightly soluble in methanol.  "Chew BP, Park JS. Carotenoid action on the immune response. J Nutr. 2004 Jan;134(1):257S-261S. PMID: 14704330.

 

Stahl W, Sies H. The role of carotenoids and retinoids in gap junctional communication. Int J Vitam Nutr Res. 1998;68(6):354-9. PMID: 9857261.

 

Palozza P, Luberto C, Ricci P, et al. Effect of beta-carotene and canthaxanthin on tert-butyl hydroperoxide-induced lipid peroxidation in murine normal and tumor thymocytes. Arch Biochem Biophys. 1996 Jan 15;325(2):145-51. PMID: 8561491.

 

Pung A, Rundhaug JE, Yoshizawa CN, et al. Beta-carotene and canthaxanthin inhibit chemically- and physically-induced neoplastic transformation in 10T1/2 cells. Carcinogenesis. 1988 Sep;9(9):1533-9. PMID: 3136943.

" Not dangerous goods.

LKT C0169 Carbenoxolone Disodium 1 g 50.2 Synthetic derivative of glycyrrhizin; connexin and 11β-hydroxysteroid dehydrogenase inhibitor. (3β,20β)-3-(3-Carboxy-1-oxopropoxy)-11-oxoolean- 12-en-29-oic acid 18β-Glycyrrhetic acid hydrogen succinate; Carbenoxalone 7421-40-1 ≥97% 614.7 C34H48Na2O7 CC1(C2CCC3(C(C2(CCC1OC(=O)CCC(=O)[O-])C)C(=O)C=C4C3(CCC5(C4CC(CC5)(C)C(=O)[O-])C)C)C)C.[Na+].[Na+] Ambient Ambient Soluble in water. Insoluble in chloroform. "Chen G, Park CK, Xie RG, et al. Connexin-43 induces chemokine release from spinal cord astrocytes to maintain late-phase neuropathic pain in mice. Brain. 2014 Aug;137(Pt 8):2193-209. PMID: 24919967.

 

Beraki S, Litrus L, Soriano L, et al. A pharmacological screening approach for discovery of neuroprotective compounds in ischemic stroke. PLoS One. 2013 Jul 18;8(7):e69233. PMID: 23874920.

 

Rhee SD, Kim CH, Park JS, et al. Carbenoxolone prevents the development of fatty liver in C57BL/6-Lep ob/ob mice via the inhibition of sterol regulatory element binding protein-1c activity and apoptosis. Eur J Pharmacol. 2012 Sep 15;691(1-3):9-18. PMID: 22742899.

 

Endong L, Shijie J, Sonobe Y, et al. The gap-junction inhibitor carbenoxolone suppresses the differentiation of Th17 cells through inhibition of IL-23 expression in antigen presenting cells. J Neuroimmunol. 2011 Dec 15;240-241:58-64. PMID: 22036952.

 

Chávez-Piña AE, Tapia-Álvarez GR, Reyes-Ramínrez A, et al. Carbenoxolone gastroprotective mechanism: participation of nitric oxide/(c) GMP/K(ATP) pathway in ethanol-induced gastric injury in the rat. Fundam Clin Pharmacol. 2011 Dec;25(6):717-22. PMID: 21105909.

" Xn, Xi Not dangerous goods.

LKT C0169 Carbenoxolone Disodium 5 g 160.2 Synthetic derivative of glycyrrhizin; connexin and 11β-hydroxysteroid dehydrogenase inhibitor. (3β,20β)-3-(3-Carboxy-1-oxopropoxy)-11-oxoolean- 12-en-29-oic acid 18β-Glycyrrhetic acid hydrogen succinate; Carbenoxalone 7421-40-1 ≥97% 614.7 C34H48Na2O7 CC1(C2CCC3(C(C2(CCC1OC(=O)CCC(=O)[O-])C)C(=O)C=C4C3(CCC5(C4CC(CC5)(C)C(=O)[O-])C)C)C)C.[Na+].[Na+] Ambient Ambient Soluble in water. Insoluble in chloroform. "Chen G, Park CK, Xie RG, et al. Connexin-43 induces chemokine release from spinal cord astrocytes to maintain late-phase neuropathic pain in mice. Brain. 2014 Aug;137(Pt 8):2193-209. PMID: 24919967.

 

Beraki S, Litrus L, Soriano L, et al. A pharmacological screening approach for discovery of neuroprotective compounds in ischemic stroke. PLoS One. 2013 Jul 18;8(7):e69233. PMID: 23874920.

 

Rhee SD, Kim CH, Park JS, et al. Carbenoxolone prevents the development of fatty liver in C57BL/6-Lep ob/ob mice via the inhibition of sterol regulatory element binding protein-1c activity and apoptosis. Eur J Pharmacol. 2012 Sep 15;691(1-3):9-18. PMID: 22742899.

 

Endong L, Shijie J, Sonobe Y, et al. The gap-junction inhibitor carbenoxolone suppresses the differentiation of Th17 cells through inhibition of IL-23 expression in antigen presenting cells. J Neuroimmunol. 2011 Dec 15;240-241:58-64. PMID: 22036952.

 

Chávez-Piña AE, Tapia-Álvarez GR, Reyes-Ramínrez A, et al. Carbenoxolone gastroprotective mechanism: participation of nitric oxide/(c) GMP/K(ATP) pathway in ethanol-induced gastric injury in the rat. Fundam Clin Pharmacol. 2011 Dec;25(6):717-22. PMID: 21105909.

" Xn, Xi Not dangerous goods.

LKT C0169 Carbenoxolone Disodium 25 g 510.3 Synthetic derivative of glycyrrhizin; connexin and 11β-hydroxysteroid dehydrogenase inhibitor. (3β,20β)-3-(3-Carboxy-1-oxopropoxy)-11-oxoolean- 12-en-29-oic acid 18β-Glycyrrhetic acid hydrogen succinate; Carbenoxalone 7421-40-1 ≥97% 614.7 C34H48Na2O7 CC1(C2CCC3(C(C2(CCC1OC(=O)CCC(=O)[O-])C)C(=O)C=C4C3(CCC5(C4CC(CC5)(C)C(=O)[O-])C)C)C)C.[Na+].[Na+] Ambient Ambient Soluble in water. Insoluble in chloroform. "Chen G, Park CK, Xie RG, et al. Connexin-43 induces chemokine release from spinal cord astrocytes to maintain late-phase neuropathic pain in mice. Brain. 2014 Aug;137(Pt 8):2193-209. PMID: 24919967.

 

Beraki S, Litrus L, Soriano L, et al. A pharmacological screening approach for discovery of neuroprotective compounds in ischemic stroke. PLoS One. 2013 Jul 18;8(7):e69233. PMID: 23874920.

 

Rhee SD, Kim CH, Park JS, et al. Carbenoxolone prevents the development of fatty liver in C57BL/6-Lep ob/ob mice via the inhibition of sterol regulatory element binding protein-1c activity and apoptosis. Eur J Pharmacol. 2012 Sep 15;691(1-3):9-18. PMID: 22742899.

 

Endong L, Shijie J, Sonobe Y, et al. The gap-junction inhibitor carbenoxolone suppresses the differentiation of Th17 cells through inhibition of IL-23 expression in antigen presenting cells. J Neuroimmunol. 2011 Dec 15;240-241:58-64. PMID: 22036952.

 

Chávez-Piña AE, Tapia-Álvarez GR, Reyes-Ramínrez A, et al. Carbenoxolone gastroprotective mechanism: participation of nitric oxide/(c) GMP/K(ATP) pathway in ethanol-induced gastric injury in the rat. Fundam Clin Pharmacol. 2011 Dec;25(6):717-22. PMID: 21105909.

" Xn, Xi Not dangerous goods.

LKT C0171 Carboplatin 25 mg 40.7 Pt-based DNA cross-linker. (SP-4-2)-Diammine-[1,1-cyclobutanedi(carboxylato- κO)(2-)]platinum Paraplati; cis-Diammine[1,1 cyclobutane dicarboxylato] platinum 41575-94-4 ≥98% 371.25 C6H12N2O4Pt C1CC(C1)(C(=O)[O-])C(=O)[O-].N.N.[Pt+2] Ambient -20°C Soluble in water. "Hato SV, Khong A, de Vries IJ, et al. Molecular pathways: the immunogenic effects of platinum-based chemotherapeutics. Clin Cancer Res. 2014 Jun 1;20(11):2831-7. PMID: 24879823.

 

Chen X, Wu Y, Dong H, et al. Platinum-based agents for individualized cancer treatment. Curr Mol Med. 2013 Dec;13(10):1603-12. PMID: 24206132.

 

Ang WH, Myint M, Lippard SJ. Transcription inhibition by platinum-DNA cross-links in live mammalian cells. J Am Chem Soc. 2010 Jun 2;132(21):7429-35. PMID: 20443565.

" Xn, Carc., Repr. Not dangerous goods.

LKT C0171 Carboplatin 100 mg 149.5 Pt-based DNA cross-linker. (SP-4-2)-Diammine-[1,1-cyclobutanedi(carboxylato- κO)(2-)]platinum Paraplati; cis-Diammine[1,1 cyclobutane dicarboxylato] platinum 41575-94-4 ≥98% 371.25 C6H12N2O4Pt C1CC(C1)(C(=O)[O-])C(=O)[O-].N.N.[Pt+2] Ambient -20°C Soluble in water. "Hato SV, Khong A, de Vries IJ, et al. Molecular pathways: the immunogenic effects of platinum-based chemotherapeutics. Clin Cancer Res. 2014 Jun 1;20(11):2831-7. PMID: 24879823.

 

Chen X, Wu Y, Dong H, et al. Platinum-based agents for individualized cancer treatment. Curr Mol Med. 2013 Dec;13(10):1603-12. PMID: 24206132.

 

Ang WH, Myint M, Lippard SJ. Transcription inhibition by platinum-DNA cross-links in live mammalian cells. J Am Chem Soc. 2010 Jun 2;132(21):7429-35. PMID: 20443565.

" Xn, Carc., Repr. Not dangerous goods.

LKT C0171 Carboplatin 250 mg 305.9 Pt-based DNA cross-linker. (SP-4-2)-Diammine-[1,1-cyclobutanedi(carboxylato- κO)(2-)]platinum Paraplati; cis-Diammine[1,1 cyclobutane dicarboxylato] platinum 41575-94-4 ≥98% 371.25 C6H12N2O4Pt C1CC(C1)(C(=O)[O-])C(=O)[O-].N.N.[Pt+2] Ambient -20°C Soluble in water. "Hato SV, Khong A, de Vries IJ, et al. Molecular pathways: the immunogenic effects of platinum-based chemotherapeutics. Clin Cancer Res. 2014 Jun 1;20(11):2831-7. PMID: 24879823.

 

Chen X, Wu Y, Dong H, et al. Platinum-based agents for individualized cancer treatment. Curr Mol Med. 2013 Dec;13(10):1603-12. PMID: 24206132.

 

Ang WH, Myint M, Lippard SJ. Transcription inhibition by platinum-DNA cross-links in live mammalian cells. J Am Chem Soc. 2010 Jun 2;132(21):7429-35. PMID: 20443565.

" Xn, Carc., Repr. Not dangerous goods.

LKT C0269 β-Carotene 1 g 20.4 Red-orange terpene pigment found in various plants and fruits, vitamin A prodrug. β,β-Carotene Carotaben; Provatene; Solatene 7235-40-7 ≥97% 536.87 C40H56 CC1=C(C(CCC1)(C)C)C=CC(=CC=CC(=CC=CC=C(C)C=CC=C(C)C=CC2=C(CCCC2(C)C)C)C)C Ambient -20°C Insoluble in water. Sparingly soluble in ethanol. Soluble in benzene or chloroform. "Abdel-Mageed WM, Bayoumi SA, Salama AA, et al. Antioxidant lipoxygenase inhibitors from the leaf extracts of Simmondsia chinensis. Asian Pac J Trop Med. 2014 Sep;7S1:S521-6. PMID: 25312177.

 

Berti AP, Düsman E, Mariucci RG, et al. Antimutagenic and radioprotective activities of beta-carotene against the biological effects of iodine-131 radiopharmaceutical in Wistar rats. Genet Mol Res. 2014 Mar 31;13(1):2248-58. PMID: 24737473.

 

Gloria NF, Soares N, Brand C, et al. Lycopene and beta-carotene induce cell-cycle arrest and apoptosis in human breast cancer cell lines. Anticancer Res. 2014 Mar;34(3):1377-86. PMID: 24596385.

 

Silva LS, de Miranda AM, de Brito Magalhães CL, et al. Diet supplementation with beta-carotene improves the serum lipid profile in rats fed a cholesterol-enriched diet. J Physiol Biochem. 2013 Dec;69(4):811-20. PMID: 23645541.

 

Di Tomo P, Canali R, Ciavardelli D, et al. β-Carotene and lycopene affect endothelial response to TNF-α reducing nitro-oxidative stress and interaction with monocytes. Mol Nutr Food Res. 2012 Feb;56(2):217-27. PMID: 22162208.

 

Amengual J, Gouranton E, van Helden YG, et al. Beta-carotene reduces body adiposity of mice via BCMO1. PLoS One. 2011;6(6):e20644. PMID: 21673813.

" Xn, Xi Not dangerous goods.

LKT C0269 β-Carotene 5 g 40.7 Red-orange terpene pigment found in various plants and fruits, vitamin A prodrug. β,β-Carotene Carotaben; Provatene; Solatene 7235-40-7 ≥97% 536.87 C40H56 CC1=C(C(CCC1)(C)C)C=CC(=CC=CC(=CC=CC=C(C)C=CC=C(C)C=CC2=C(CCCC2(C)C)C)C)C Ambient -20°C Insoluble in water. Sparingly soluble in ethanol. Soluble in benzene or chloroform. "Abdel-Mageed WM, Bayoumi SA, Salama AA, et al. Antioxidant lipoxygenase inhibitors from the leaf extracts of Simmondsia chinensis. Asian Pac J Trop Med. 2014 Sep;7S1:S521-6. PMID: 25312177.

 

Berti AP, Düsman E, Mariucci RG, et al. Antimutagenic and radioprotective activities of beta-carotene against the biological effects of iodine-131 radiopharmaceutical in Wistar rats. Genet Mol Res. 2014 Mar 31;13(1):2248-58. PMID: 24737473.

 

Gloria NF, Soares N, Brand C, et al. Lycopene and beta-carotene induce cell-cycle arrest and apoptosis in human breast cancer cell lines. Anticancer Res. 2014 Mar;34(3):1377-86. PMID: 24596385.

 

Silva LS, de Miranda AM, de Brito Magalhães CL, et al. Diet supplementation with beta-carotene improves the serum lipid profile in rats fed a cholesterol-enriched diet. J Physiol Biochem. 2013 Dec;69(4):811-20. PMID: 23645541.

 

Di Tomo P, Canali R, Ciavardelli D, et al. β-Carotene and lycopene affect endothelial response to TNF-α reducing nitro-oxidative stress and interaction with monocytes. Mol Nutr Food Res. 2012 Feb;56(2):217-27. PMID: 22162208.

 

Amengual J, Gouranton E, van Helden YG, et al. Beta-carotene reduces body adiposity of mice via BCMO1. PLoS One. 2011;6(6):e20644. PMID: 21673813.

" Xn, Xi Not dangerous goods.

LKT C0368 Carveol 5 g 52.3 Terpene alcohol found in spearmint oil; TRPV3 agonist. p-Mentha-6,8-dien-2-ol 99-48-9 ≥98% 152.23 C10H16O CC1=CCC(CC1O)C(=C)C Ambient Ambient Insoluble in water. Soluble in ethanol, or DMSO. "Yang JY, Kim MG, Lee SE, et al. Acaricidal activities against house dust mites of spearmint oil and its constituents. Planta Med. 2014 Feb;80(2-3):165-70. PMID: 24488719.

 

Bhatia SP, McGinty D, Letizia CS, et al. Fragrance material review on carveol. Food Chem Toxicol. 2008 Nov;46 Suppl 11:S85-7. PMID: 18640224.

 

Vogt-Eisele AK, Weber K, Sherkheli MA, et al. Monoterpenoid agonists of TRPV3. Br J Pharmacol. 2007 Jun;151(4):530-40. PMID: 17420775.

 

Chen J, Lu M, Jing Y, et al. The synthesis of L-carvone and limonene derivatives with increased antiproliferative effect and activation of ERK pathway in prostate cancer cells. Bioorg Med Chem. 2006 Oct 1;14(19):6539-47. PMID: 16806947.

" Xi Not dangerous goods.

LKT C0368 Carveol 25 g 170.7 Terpene alcohol found in spearmint oil; TRPV3 agonist. p-Mentha-6,8-dien-2-ol 99-48-9 ≥98% 152.23 C10H16O CC1=CCC(CC1O)C(=C)C Ambient Ambient Insoluble in water. Soluble in ethanol, or DMSO. "Yang JY, Kim MG, Lee SE, et al. Acaricidal activities against house dust mites of spearmint oil and its constituents. Planta Med. 2014 Feb;80(2-3):165-70. PMID: 24488719.

 

Bhatia SP, McGinty D, Letizia CS, et al. Fragrance material review on carveol. Food Chem Toxicol. 2008 Nov;46 Suppl 11:S85-7. PMID: 18640224.

 

Vogt-Eisele AK, Weber K, Sherkheli MA, et al. Monoterpenoid agonists of TRPV3. Br J Pharmacol. 2007 Jun;151(4):530-40. PMID: 17420775.

 

Chen J, Lu M, Jing Y, et al. The synthesis of L-carvone and limonene derivatives with increased antiproliferative effect and activation of ERK pathway in prostate cancer cells. Bioorg Med Chem. 2006 Oct 1;14(19):6539-47. PMID: 16806947.

" Xi Not dangerous goods.

LKT C2800 Chalcone 25 g 44.9 Enone. 1,3-Diphenyl-2-propen-1-one Chalkone; trans-Benzylideneacetophenone 94-41-7 ≥97% 208.26 C15H12O C1=CC=C(C=C1)C=CC(=O)C2=CC=CC=C2 Ambient Ambient Insoluble in water.  Slightly soluble in ethanol. "Wu JZ, Cheng CC, Shen LL, et al. Synthetic Chalcones with Potent Antioxidant Ability on H2O2-Induced Apoptosis in PC12 Cells. Int J Mol Sci. 2014 Oct 14;15(10):18525-18539. PMID: 25318055.

 

Jantan I, Bukhari SN, Adekoya OA, et al. Studies of synthetic chalcone derivatives as potential inhibitors of secretory phospholipase A2, cyclooxygenases, lipoxygenase and pro-inflammatory cytokines. Drug Des Devel Ther. 2014 Sep 16;8:1405-18. PMID: 25258510.

 

Abdellatif KR, Elshemy HA, Salama SA, et al. Synthesis, characterization and biological evaluation of novel 4'-fluoro-2'-hydroxy-chalcone derivatives as antioxidant, anti-inflammatory and analgesic agents. J Enzyme Inhib Med Chem. 2014 Sep 8:1-8. PMID: 25198887.

 

Karthikeyan C, Narayana Moorthy NS, Ramasamy S, et al. Advances in Chalcones with Anticancer Activities. Recent Pat Anticancer Drug Discov. 2014 Aug 19. [Epub ahead of print]. PMID: 25138130.

 

Shivahare R, Korthikunta V, Chandasana H, et al. Synthesis, structure-activity relationships, and biological studies of chromenochalcones as potential antileishmanial agents. J Med Chem. 2014 Apr 24;57(8):3342-57. PMID: 24635539.

" Xn, Xi Not dangerous goods.

LKT C2800 Chalcone 100 g 104.6 Enone. 1,3-Diphenyl-2-propen-1-one Chalkone; trans-Benzylideneacetophenone 94-41-7 ≥97% 208.26 C15H12O C1=CC=C(C=C1)C=CC(=O)C2=CC=CC=C2 Ambient Ambient Insoluble in water.  Slightly soluble in ethanol. "Wu JZ, Cheng CC, Shen LL, et al. Synthetic Chalcones with Potent Antioxidant Ability on H2O2-Induced Apoptosis in PC12 Cells. Int J Mol Sci. 2014 Oct 14;15(10):18525-18539. PMID: 25318055.

 

Jantan I, Bukhari SN, Adekoya OA, et al. Studies of synthetic chalcone derivatives as potential inhibitors of secretory phospholipase A2, cyclooxygenases, lipoxygenase and pro-inflammatory cytokines. Drug Des Devel Ther. 2014 Sep 16;8:1405-18. PMID: 25258510.

 

Abdellatif KR, Elshemy HA, Salama SA, et al. Synthesis, characterization and biological evaluation of novel 4'-fluoro-2'-hydroxy-chalcone derivatives as antioxidant, anti-inflammatory and analgesic agents. J Enzyme Inhib Med Chem. 2014 Sep 8:1-8. PMID: 25198887.

 

Karthikeyan C, Narayana Moorthy NS, Ramasamy S, et al. Advances in Chalcones with Anticancer Activities. Recent Pat Anticancer Drug Discov. 2014 Aug 19. [Epub ahead of print]. PMID: 25138130.

 

Shivahare R, Korthikunta V, Chandasana H, et al. Synthesis, structure-activity relationships, and biological studies of chromenochalcones as potential antileishmanial agents. J Med Chem. 2014 Apr 24;57(8):3342-57. PMID: 24635539.

" Xn, Xi Not dangerous goods.

LKT C2816 Cheirolin 25 mg 152.4 Naturally produced ITC, sulfonyl analog of sulforaphane. 1-Isothiocyanato-3-(methylsulfonyl)-propane 505-34-0 ≥97% 179.26 C5H9NO2S2 CS(=O)(=O)CCCN=C=S Ambient -20°C Slightly soluble in water, ether; freely soluble in alcohol, chloroform, ethyl acetate. Ernst IM, Palani K, Esatbeyoglu T, et al. Synthesis and Nrf2-inducing activity of the isothiocyanates iberverin, iberin and cheirolin. Pharmacol Res. 2013 Apr;70(1):155-62. PMID: 23403058. Not dangerous goods.

LKT C2816 Cheirolin 50 mg 255 Naturally produced ITC, sulfonyl analog of sulforaphane. 1-Isothiocyanato-3-(methylsulfonyl)-propane 505-34-0 ≥97% 179.26 C5H9NO2S2 CS(=O)(=O)CCCN=C=S Ambient -20°C Slightly soluble in water, ether; freely soluble in alcohol, chloroform, ethyl acetate. Ernst IM, Palani K, Esatbeyoglu T, et al. Synthesis and Nrf2-inducing activity of the isothiocyanates iberverin, iberin and cheirolin. Pharmacol Res. 2013 Apr;70(1):155-62. PMID: 23403058. Not dangerous goods.

LKT C2816 Cheirolin 100 mg 468.2 Naturally produced ITC, sulfonyl analog of sulforaphane. 1-Isothiocyanato-3-(methylsulfonyl)-propane 505-34-0 ≥97% 179.26 C5H9NO2S2 CS(=O)(=O)CCCN=C=S Ambient -20°C Slightly soluble in water, ether; freely soluble in alcohol, chloroform, ethyl acetate. Ernst IM, Palani K, Esatbeyoglu T, et al. Synthesis and Nrf2-inducing activity of the isothiocyanates iberverin, iberin and cheirolin. Pharmacol Res. 2013 Apr;70(1):155-62. PMID: 23403058. Not dangerous goods.

LKT C2816 Cheirolin 500 mg 1517.1 Naturally produced ITC, sulfonyl analog of sulforaphane. 1-Isothiocyanato-3-(methylsulfonyl)-propane 505-34-0 ≥97% 179.26 C5H9NO2S2 CS(=O)(=O)CCCN=C=S Ambient -20°C Slightly soluble in water, ether; freely soluble in alcohol, chloroform, ethyl acetate. Ernst IM, Palani K, Esatbeyoglu T, et al. Synthesis and Nrf2-inducing activity of the isothiocyanates iberverin, iberin and cheirolin. Pharmacol Res. 2013 Apr;70(1):155-62. PMID: 23403058. Not dangerous goods.

LKT C2944 Chlorogenic Acid (from Lonicera) 100 mg 25.2 Polyphenol derivative of caffeic acid found in Lonicera; DNMT and G6P translocase inhibitor, potential pepsin inhibitor. [1S-(1α,3β,4α,5α)]-3-[[3-(3,4-Dihydroxyphenyl)-1- oxo-2-propenyl]oxy]-1,4,5-trihydroxycyclohexane- carboxylic acid 3-Caffeoylquinic acid 327-97-9 ≥98% 354.31 C16H18O9 C1C(C(C(CC1(C(=O)O)O)OC(=O)C=CC2=CC(=C(C=C2)O)O)O)O Ambient Ambient Soluble in ethanol or acetone. "Zeng HJ, Liang HL, You J, et al. Study on the binding of chlorogenic acid to pepsin by spectral and molecular docking. Luminescence. 2013 Dec 12. [Epub ahead of print]. PMID: 24339327.

 

Luís A, Silva F, Sousa S, et al. Antistaphylococcal and biofilm inhibitory activities of gallic, caffeic, and chlorogenic acids. Biofouling. 2014 Jan;30(1):69-79. PMID: 24228999.

 

Shi H, Dong L, Jiang J, et al. Chlorogenic acid reduces liver inflammation and fibrosis through inhibition of toll-like receptor 4 signaling pathway. Toxicology. 2013 Jan 7;303:107-14. PMID: 23146752.

 

Teraoka M, Nakaso K, Kusumoto C, et al. Cytoprotective effect of chlorogenic acid against α-synuclein-related toxicity in catecholaminergic PC12 cells. J Clin Biochem Nutr. 2012 Sep;51(2):122-7. PMID: 22962530.

 

Lou Z, Wang H, Zhu S, et al. Antibacterial activity and mechanism of action of chlorogenic acid. J Food Sci. 2011 Aug;76(6):M398-403. PMID: 22417510.

 

Qin HD, Shi YQ, Liu ZH, et al. Effect of chlorogenic acid on mast cell-dependent anaphylactic reaction. Int Immunopharmacol. 2010 Sep;10(9):1135-41. PMID: 20620227.

 

Belkaid A, Currie JC, Desgagnés J, et al. The chemopreventive properties of chlorogenic acid reveal a potential new role for the microsomal glucose-6-phosphate translocase in brain tumor progression. Cancer Cell Int. 2006 Mar 27;6:7. PMID: 16566826.

 

Lee WJ, Zhu BT. Inhibition of DNA methylation by caffeic acid and chlorogenic acid, two common catechol-containing coffee polyphenols.

" Xn Not dangerous goods.

LKT C2944 Chlorogenic Acid (from Lonicera) 250 mg 38.1 Polyphenol derivative of caffeic acid found in Lonicera; DNMT and G6P translocase inhibitor, potential pepsin inhibitor. [1S-(1α,3β,4α,5α)]-3-[[3-(3,4-Dihydroxyphenyl)-1- oxo-2-propenyl]oxy]-1,4,5-trihydroxycyclohexane- carboxylic acid 3-Caffeoylquinic acid 327-97-9 ≥98% 354.31 C16H18O9 C1C(C(C(CC1(C(=O)O)O)OC(=O)C=CC2=CC(=C(C=C2)O)O)O)O Ambient Ambient Soluble in ethanol or acetone. "Zeng HJ, Liang HL, You J, et al. Study on the binding of chlorogenic acid to pepsin by spectral and molecular docking. Luminescence. 2013 Dec 12. [Epub ahead of print]. PMID: 24339327.

 

Luís A, Silva F, Sousa S, et al. Antistaphylococcal and biofilm inhibitory activities of gallic, caffeic, and chlorogenic acids. Biofouling. 2014 Jan;30(1):69-79. PMID: 24228999.

 

Shi H, Dong L, Jiang J, et al. Chlorogenic acid reduces liver inflammation and fibrosis through inhibition of toll-like receptor 4 signaling pathway. Toxicology. 2013 Jan 7;303:107-14. PMID: 23146752.

 

Teraoka M, Nakaso K, Kusumoto C, et al. Cytoprotective effect of chlorogenic acid against α-synuclein-related toxicity in catecholaminergic PC12 cells. J Clin Biochem Nutr. 2012 Sep;51(2):122-7. PMID: 22962530.

 

Lou Z, Wang H, Zhu S, et al. Antibacterial activity and mechanism of action of chlorogenic acid. J Food Sci. 2011 Aug;76(6):M398-403. PMID: 22417510.

 

Qin HD, Shi YQ, Liu ZH, et al. Effect of chlorogenic acid on mast cell-dependent anaphylactic reaction. Int Immunopharmacol. 2010 Sep;10(9):1135-41. PMID: 20620227.

 

Belkaid A, Currie JC, Desgagnés J, et al. The chemopreventive properties of chlorogenic acid reveal a potential new role for the microsomal glucose-6-phosphate translocase in brain tumor progression. Cancer Cell Int. 2006 Mar 27;6:7. PMID: 16566826.

 

Lee WJ, Zhu BT. Inhibition of DNA methylation by caffeic acid and chlorogenic acid, two common catechol-containing coffee polyphenols.

" Xn Not dangerous goods.

LKT C2944 Chlorogenic Acid (from Lonicera) 1 g 92.5 Polyphenol derivative of caffeic acid found in Lonicera; DNMT and G6P translocase inhibitor, potential pepsin inhibitor. [1S-(1α,3β,4α,5α)]-3-[[3-(3,4-Dihydroxyphenyl)-1- oxo-2-propenyl]oxy]-1,4,5-trihydroxycyclohexane- carboxylic acid 3-Caffeoylquinic acid 327-97-9 ≥98% 354.31 C16H18O9 C1C(C(C(CC1(C(=O)O)O)OC(=O)C=CC2=CC(=C(C=C2)O)O)O)O Ambient Ambient Soluble in ethanol or acetone. "Zeng HJ, Liang HL, You J, et al. Study on the binding of chlorogenic acid to pepsin by spectral and molecular docking. Luminescence. 2013 Dec 12. [Epub ahead of print]. PMID: 24339327.

 

Luís A, Silva F, Sousa S, et al. Antistaphylococcal and biofilm inhibitory activities of gallic, caffeic, and chlorogenic acids. Biofouling. 2014 Jan;30(1):69-79. PMID: 24228999.

 

Shi H, Dong L, Jiang J, et al. Chlorogenic acid reduces liver inflammation and fibrosis through inhibition of toll-like receptor 4 signaling pathway. Toxicology. 2013 Jan 7;303:107-14. PMID: 23146752.

 

Teraoka M, Nakaso K, Kusumoto C, et al. Cytoprotective effect of chlorogenic acid against α-synuclein-related toxicity in catecholaminergic PC12 cells. J Clin Biochem Nutr. 2012 Sep;51(2):122-7. PMID: 22962530.

 

Lou Z, Wang H, Zhu S, et al. Antibacterial activity and mechanism of action of chlorogenic acid. J Food Sci. 2011 Aug;76(6):M398-403. PMID: 22417510.

 

Qin HD, Shi YQ, Liu ZH, et al. Effect of chlorogenic acid on mast cell-dependent anaphylactic reaction. Int Immunopharmacol. 2010 Sep;10(9):1135-41. PMID: 20620227.

 

Belkaid A, Currie JC, Desgagnés J, et al. The chemopreventive properties of chlorogenic acid reveal a potential new role for the microsomal glucose-6-phosphate translocase in brain tumor progression. Cancer Cell Int. 2006 Mar 27;6:7. PMID: 16566826.

 

Lee WJ, Zhu BT. Inhibition of DNA methylation by caffeic acid and chlorogenic acid, two common catechol-containing coffee polyphenols.

" Xn Not dangerous goods.

LKT C2945 Chlorophyllin Sodium-Copper Salt 5 g 27.9 Semi-synthetic derivative of chlorophyll; food additive. Chlorophyllin A 15611-43-5 ≥98% 654.21 C34H34MgN4O6 [H+].[H+].[H+].CCC1=C(C2=CC3=NC(=CC4=NC(=C(C5=NC(=C(C5=C([O-])[O-])C)C=C1[N-]2)CC(=O)[O-])C(C4C)CCC(=O)[O-])C(=C3C=C)C)C.[Mg+2] Ambient Ambient Soluble in water, slightly soluble in alcohol and chloroform "Lihuan D, Jingcun Z, Ning J, et al. Photodynamic therapy with the novel photosensitizer chlorophyllin f induces apoptosis and autophagy in human bladder cancer cells. Lasers Surg Med. 2014 Apr;46(4):319-34. PMID: 24464873.

 

Nagini S, Vidya Priyadarsini R, Veeravarmal V, et al. Chlorophyllin abrogates canonical Wnt/β-catenin signaling and angiogenesis to inhibit the development of DMBA-induced hamster cheek pouch carcinomas. Cell Oncol (Dordr). 2012 Oct;35(5):385-95. Erratum in: Cell Oncol (Dordr). 2013 Apr;36(2):179. PMID: 22983718.

 

Keshava C, Divi RL, Einem TL, et al. Chlorophyllin significantly reduces benzo[a]pyrene-DNA adduct formation and alters cytochrome P450 1A1 and 1B1 expression and EROD activity in normal human mammary epithelial cells. Environ Mol Mutagen. 2009 Mar;50(2):134-44. PMID: 19152381.

 

Castro DJ, Löhr CV, Fischer KA, et al. Identifying efficacious approaches to chemoprevention with chlorophyllin, purified chlorophylls and freeze-dried spinach in a mouse model of transplacental carcinogenesis. Carcinogenesis. 2009 Feb;30(2):315-20. PMID: 19073876.

" Not dangerous goods.

LKT C2945 Chlorophyllin Sodium-Copper Salt 25 g 70.2 Semi-synthetic derivative of chlorophyll; food additive. Chlorophyllin A 15611-43-5 ≥98% 654.21 C34H34MgN4O6 [H+].[H+].[H+].CCC1=C(C2=CC3=NC(=CC4=NC(=C(C5=NC(=C(C5=C([O-])[O-])C)C=C1[N-]2)CC(=O)[O-])C(C4C)CCC(=O)[O-])C(=C3C=C)C)C.[Mg+2] Ambient Ambient Soluble in water, slightly soluble in alcohol and chloroform "Lihuan D, Jingcun Z, Ning J, et al. Photodynamic therapy with the novel photosensitizer chlorophyllin f induces apoptosis and autophagy in human bladder cancer cells. Lasers Surg Med. 2014 Apr;46(4):319-34. PMID: 24464873.

 

Nagini S, Vidya Priyadarsini R, Veeravarmal V, et al. Chlorophyllin abrogates canonical Wnt/β-catenin signaling and angiogenesis to inhibit the development of DMBA-induced hamster cheek pouch carcinomas. Cell Oncol (Dordr). 2012 Oct;35(5):385-95. Erratum in: Cell Oncol (Dordr). 2013 Apr;36(2):179. PMID: 22983718.

 

Keshava C, Divi RL, Einem TL, et al. Chlorophyllin significantly reduces benzo[a]pyrene-DNA adduct formation and alters cytochrome P450 1A1 and 1B1 expression and EROD activity in normal human mammary epithelial cells. Environ Mol Mutagen. 2009 Mar;50(2):134-44. PMID: 19152381.

 

Castro DJ, Löhr CV, Fischer KA, et al. Identifying efficacious approaches to chemoprevention with chlorophyllin, purified chlorophylls and freeze-dried spinach in a mouse model of transplacental carcinogenesis. Carcinogenesis. 2009 Feb;30(2):315-20. PMID: 19073876.

" Not dangerous goods.

LKT C2945 Chlorophyllin Sodium-Copper Salt 100 g 245.1 Semi-synthetic derivative of chlorophyll; food additive. Chlorophyllin A 15611-43-5 ≥98% 654.21 C34H34MgN4O6 [H+].[H+].[H+].CCC1=C(C2=CC3=NC(=CC4=NC(=C(C5=NC(=C(C5=C([O-])[O-])C)C=C1[N-]2)CC(=O)[O-])C(C4C)CCC(=O)[O-])C(=C3C=C)C)C.[Mg+2] Ambient Ambient Soluble in water, slightly soluble in alcohol and chloroform "Lihuan D, Jingcun Z, Ning J, et al. Photodynamic therapy with the novel photosensitizer chlorophyllin f induces apoptosis and autophagy in human bladder cancer cells. Lasers Surg Med. 2014 Apr;46(4):319-34. PMID: 24464873.

 

Nagini S, Vidya Priyadarsini R, Veeravarmal V, et al. Chlorophyllin abrogates canonical Wnt/β-catenin signaling and angiogenesis to inhibit the development of DMBA-induced hamster cheek pouch carcinomas. Cell Oncol (Dordr). 2012 Oct;35(5):385-95. Erratum in: Cell Oncol (Dordr). 2013 Apr;36(2):179. PMID: 22983718.

 

Keshava C, Divi RL, Einem TL, et al. Chlorophyllin significantly reduces benzo[a]pyrene-DNA adduct formation and alters cytochrome P450 1A1 and 1B1 expression and EROD activity in normal human mammary epithelial cells. Environ Mol Mutagen. 2009 Mar;50(2):134-44. PMID: 19152381.

 

Castro DJ, Löhr CV, Fischer KA, et al. Identifying efficacious approaches to chemoprevention with chlorophyllin, purified chlorophylls and freeze-dried spinach in a mouse model of transplacental carcinogenesis. Carcinogenesis. 2009 Feb;30(2):315-20. PMID: 19073876.

" Not dangerous goods.

LKT C2956 Cholecalciferol 1 g 32.3 Endogenous vitamin D prodrug. (3b,5Z,7E)-9,10-Secocholesta-5,7,10(19)-trien-3-ol oleovitamin D3; Vitamin D3 67-97-0 ≥98% 384.64 C27H44O CC(C)CCCC(C)C1CCC2C1(CCCC2=CC=C3CC(CCC3=C)O)C Ambient 4°C Insoluble in water. Soluble in most organic solvents. "Bendik I, Friedel A, Roos FF, et al. Vitamin D: a critical and essential micronutrient for human health. Front Physiol. 2014 Jul 11;5:248. PMID: 25071593.

 

Moukayed M, Grant WB. Molecular link between vitamin D and cancer prevention. Nutrients. 2013 Sep 30;5(10):3993-4021. PMID: 24084056.

 

Geddes JA, Inderjeeth CA. Evidence for the treatment of osteoporosis with vitamin D in residential care and in the community dwelling elderly. Biomed Res Int. 2013;2013:463589. PMID: 24058907.

" T, T+ "UN number: 2811     Class:  6.1     Packing group:  II

Proper shipping name:  Toxic solids, organic, n.o.s. (Vitamin D3)

Reportable Quantity (RQ):     Marine pollutant:  No     Poison inhalation hazard:  No"

LKT C2956 Cholecalciferol 5 g 103.6 Endogenous vitamin D prodrug. (3b,5Z,7E)-9,10-Secocholesta-5,7,10(19)-trien-3-ol oleovitamin D3; Vitamin D3 67-97-0 ≥98% 384.64 C27H44O CC(C)CCCC(C)C1CCC2C1(CCCC2=CC=C3CC(CCC3=C)O)C Ambient 4°C Insoluble in water. Soluble in most organic solvents. "Bendik I, Friedel A, Roos FF, et al. Vitamin D: a critical and essential micronutrient for human health. Front Physiol. 2014 Jul 11;5:248. PMID: 25071593.

 

Moukayed M, Grant WB. Molecular link between vitamin D and cancer prevention. Nutrients. 2013 Sep 30;5(10):3993-4021. PMID: 24084056.

 

Geddes JA, Inderjeeth CA. Evidence for the treatment of osteoporosis with vitamin D in residential care and in the community dwelling elderly. Biomed Res Int. 2013;2013:463589. PMID: 24058907.

" T, T+ "UN number: 2811     Class:  6.1     Packing group:  II

Proper shipping name:  Toxic solids, organic, n.o.s. (Vitamin D3)

Reportable Quantity (RQ):     Marine pollutant:  No     Poison inhalation hazard:  No"

LKT C2956 Cholecalciferol 25 g 323.6 Endogenous vitamin D prodrug. (3b,5Z,7E)-9,10-Secocholesta-5,7,10(19)-trien-3-ol oleovitamin D3; Vitamin D3 67-97-0 ≥98% 384.64 C27H44O CC(C)CCCC(C)C1CCC2C1(CCCC2=CC=C3CC(CCC3=C)O)C Ambient 4°C Insoluble in water. Soluble in most organic solvents. "Bendik I, Friedel A, Roos FF, et al. Vitamin D: a critical and essential micronutrient for human health. Front Physiol. 2014 Jul 11;5:248. PMID: 25071593.

 

Moukayed M, Grant WB. Molecular link between vitamin D and cancer prevention. Nutrients. 2013 Sep 30;5(10):3993-4021. PMID: 24084056.

 

Geddes JA, Inderjeeth CA. Evidence for the treatment of osteoporosis with vitamin D in residential care and in the community dwelling elderly. Biomed Res Int. 2013;2013:463589. PMID: 24058907.

" T, T+ "UN number: 2811     Class:  6.1     Packing group:  II

Proper shipping name:  Toxic solids, organic, n.o.s. (Vitamin D3)

Reportable Quantity (RQ):     Marine pollutant:  No     Poison inhalation hazard:  No"

LKT C2968 Chrysin 5 g 38.1 Flavone found in Passiflora, Oroxylum, and Pleurotis; HDAC2/8 inhibitor, potential aromatase inhibitor. 5,7-Dihydroxy-2-phenyl-4H-1-benzopyran-4-one 5,7-Dihydroxyflavone; chrysidenon 480-40-0 ≥98% 254.2 C15H10O4 C1=CC=C(C=C1)C2=CC(=O)C3=C(C=C(C=C3O2)O)O Ambient Ambient Soluble in alkali hydroxide solutions. Slightly soluble in alcohol, chloroform, or ether. Practically insoluble in water. "Li R, Zang A, Zhang L, et al. Chrysin ameliorates diabetes-associated cognitive deficits in Wistar rats. Neurol Sci. 2014 Oct;35(10):1527-32. PMID: 24737349.

 

Lirdprapamongkol K, Sakurai H, Abdelhamed S, et al. A flavonoid chrysin suppresses hypoxic survival and metastatic growth of mouse breast cancer cells. Oncol Rep. 2013 Nov;30(5):2357-64. PMID: 23969634.

 

Rehman MU, Tahir M, Khan AQ, et al. Chrysin suppresses renal carcinogenesis via amelioration of hyperproliferation, oxidative stress and inflammation: plausible role of NF-κB. Toxicol Lett. 2013 Feb 4;216(2-3):146-58. PMID: 23194824.

 

Pal-Bhadra M, Ramaiah MJ, Reddy TL, et al. Plant HDAC inhibitor chrysin arrest cell growth and induce p21WAF1 by altering chromatin of STAT response element in A375 cells. BMC Cancer. 2012 May 16;12:180. PMID: 22591439.

 

Brown E', Hurd NS, McCall S, et al. Evaluation of the anxiolytic effects of chrysin, a Passiflora incarnata extract, in the laboratory rat. AANA J. 2007 Oct;75(5):333-7. PMID: 17966676.

 

Woo KJ, Jeong YJ, Inoue H, et al. Chrysin suppresses lipopolysaccharide-induced cyclooxygenase-2 expression through the inhibition of nuclear factor for IL-6 (NF-IL6) DNA-binding activity. FEBS Lett. 2005 Jan 31;579(3):705-11. PMID: 15670832.

 

Kellis JT Jr, Vickery LE. Inhibition of human estrogen synthetase (aromatase) by flavones. Science. 1984 Sep 7;225(4666):1032-4. PMID: 6474163.

" Not dangerous goods.

LKT C2968 Chrysin 25 g 108.8 Flavone found in Passiflora, Oroxylum, and Pleurotis; HDAC2/8 inhibitor, potential aromatase inhibitor. 5,7-Dihydroxy-2-phenyl-4H-1-benzopyran-4-one 5,7-Dihydroxyflavone; chrysidenon 480-40-0 ≥98% 254.2 C15H10O4 C1=CC=C(C=C1)C2=CC(=O)C3=C(C=C(C=C3O2)O)O Ambient Ambient Soluble in alkali hydroxide solutions. Slightly soluble in alcohol, chloroform, or ether. Practically insoluble in water. "Li R, Zang A, Zhang L, et al. Chrysin ameliorates diabetes-associated cognitive deficits in Wistar rats. Neurol Sci. 2014 Oct;35(10):1527-32. PMID: 24737349.

 

Lirdprapamongkol K, Sakurai H, Abdelhamed S, et al. A flavonoid chrysin suppresses hypoxic survival and metastatic growth of mouse breast cancer cells. Oncol Rep. 2013 Nov;30(5):2357-64. PMID: 23969634.

 

Rehman MU, Tahir M, Khan AQ, et al. Chrysin suppresses renal carcinogenesis via amelioration of hyperproliferation, oxidative stress and inflammation: plausible role of NF-κB. Toxicol Lett. 2013 Feb 4;216(2-3):146-58. PMID: 23194824.

 

Pal-Bhadra M, Ramaiah MJ, Reddy TL, et al. Plant HDAC inhibitor chrysin arrest cell growth and induce p21WAF1 by altering chromatin of STAT response element in A375 cells. BMC Cancer. 2012 May 16;12:180. PMID: 22591439.

 

Brown E', Hurd NS, McCall S, et al. Evaluation of the anxiolytic effects of chrysin, a Passiflora incarnata extract, in the laboratory rat. AANA J. 2007 Oct;75(5):333-7. PMID: 17966676.

 

Woo KJ, Jeong YJ, Inoue H, et al. Chrysin suppresses lipopolysaccharide-induced cyclooxygenase-2 expression through the inhibition of nuclear factor for IL-6 (NF-IL6) DNA-binding activity. FEBS Lett. 2005 Jan 31;579(3):705-11. PMID: 15670832.

 

Kellis JT Jr, Vickery LE. Inhibition of human estrogen synthetase (aromatase) by flavones. Science. 1984 Sep 7;225(4666):1032-4. PMID: 6474163.

" Not dangerous goods.

LKT C5680 Coumestrol 10 mg 248.7 Phytoestrogen found in various plant sources; ERβ agonist, aromatase and 3α-hydroxysteroid dehydrogenase inhibitor. 3,9-Dihydroxy-6H-benzofuro[3,2-c][1]benzopyran-6- one Cumoesterol, Cumoestrol, Cumostrol 479-13-0 ≥96% 268.2 C15H8O5 C1=CC2=C(C=C1O)OC3=C2C(=O)OC4=C3C=CC(=C4)O Ambient Ambient Insoluble in water.  Slightly soluble in methanol, ethanol or chloroform. "Karieb S, Fox SW. Suppression of T cell-induced osteoclast formation. Biochem Biophys Res Commun. 2013 Jul 12;436(4):619-24. PMID: 23764400.

 

Blomquist CH, Lima PH, Hotchkiss JR. Inhibition of 3alpha-hydroxysteroid dehydrogenase (3alpha-HSD) activity of human lung microsomes by genistein, daidzein, coumestrol and C(18)-, C(19)- and C(21)-hydroxysteroids and ketosteroids. Steroids. 2005 Jul;70(8):507-14. PMID: 15894034.

 

Walf AA, Rhodes ME, Frye CA. Antidepressant effects of ERbeta-selective estrogen receptor modulators in the forced swim test. Pharmacol Biochem Behav. 2004 Jul;78(3):523-9. PMID: 15251261.

 

Kuiper GG, Lemmen JG, Carlsson B, et al. Interaction of estrogenic chemicals and phytoestrogens with estrogen receptor beta. Endocrinology. 1998 Oct;139(10):4252-63. PMID: 9751507.

" Xn, Xi Not dangerous goods.

LKT C5680 Coumestrol 25 mg 485.3 Phytoestrogen found in various plant sources; ERβ agonist, aromatase and 3α-hydroxysteroid dehydrogenase inhibitor. 3,9-Dihydroxy-6H-benzofuro[3,2-c][1]benzopyran-6- one Cumoesterol, Cumoestrol, Cumostrol 479-13-0 ≥96% 268.2 C15H8O5 C1=CC2=C(C=C1O)OC3=C2C(=O)OC4=C3C=CC(=C4)O Ambient Ambient Insoluble in water.  Slightly soluble in methanol, ethanol or chloroform. "Karieb S, Fox SW. Suppression of T cell-induced osteoclast formation. Biochem Biophys Res Commun. 2013 Jul 12;436(4):619-24. PMID: 23764400.

 

Blomquist CH, Lima PH, Hotchkiss JR. Inhibition of 3alpha-hydroxysteroid dehydrogenase (3alpha-HSD) activity of human lung microsomes by genistein, daidzein, coumestrol and C(18)-, C(19)- and C(21)-hydroxysteroids and ketosteroids. Steroids. 2005 Jul;70(8):507-14. PMID: 15894034.

 

Walf AA, Rhodes ME, Frye CA. Antidepressant effects of ERbeta-selective estrogen receptor modulators in the forced swim test. Pharmacol Biochem Behav. 2004 Jul;78(3):523-9. PMID: 15251261.

 

Kuiper GG, Lemmen JG, Carlsson B, et al. Interaction of estrogenic chemicals and phytoestrogens with estrogen receptor beta. Endocrinology. 1998 Oct;139(10):4252-63. PMID: 9751507.

" Xn, Xi Not dangerous goods.

LKT C8069 Curcumin 5 g 34.6 Diarylheptanoid found in Zingiberaceae. (1E,6E)-1,7-Bis(4-hydroxy-3-methoxyphenyl)-1,6-heptadiene-3,5-dione Turmeric yellow 458-37-7 ≥97% curcuminoid content 368.38 C21H20O6 COC1=C(C=CC(=C1)C=CC(=O)CC(=O)C=CC2=CC(=C(C=C2)O)OC)O Ambient Ambient Insoluble in water.  Soluble in ethanol (10mg/mL), DMSO (74mg/mL), chloroform, acetone, DMF.  Soluble in 0.1 M NaOH to 3 mg/mL-do not store more than 12 hours. "Kawanishi N, Kato K, Takahashi M, et al. Curcumin attenuates oxidative stress following downhill running-induced muscle damage. Biochem Biophys Res Commun. 2013 Nov 22;441(3):573-8. PMID: 24184481.

 

Du WZ, Feng Y, Wang XF, et al. Curcumin Suppresses Malignant Glioma Cells Growth and Induces Apoptosis by Inhibition of SHH/GLI1 Signaling Pathway in Vitro and Vivo. CNS Neurosci Ther. 2013 Dec;19(12):926-36. PMID: 24165291.

 

Tian N, Li X, Luo Y, et al. Curcumin regulates the metabolism of low density lipoproteins by improving the C-to-U RNA editing efficiency of apolipoprotein B in primary rat hepatocytes. Mol Med Rep. 2013 Oct 24. [Epub ahead of print]. PMID: 24173373.

 

Wang Y, Yin H, Li J, et al. Amelioration of β-amyloid-induced cognitive dysfunction and hippocampal axon degeneration by curcumin is associated with suppression of CRMP-2 hyperphosphorylation. Neurosci Lett. 2013 Oct 21. [Epub ahead of print]. PMID: 24157857.

 

Antoine F, Simard JC, Girard D. Curcumin inhibits agent-induced human neutrophil functions in vitro and lipopolysaccharide-induced neutrophilic infiltration in vivo. Int Immunopharmacol. 2013 Oct 21. [Epub ahead of print]. PMID: 24157330.

 

Gunes H, Gulen D, Mutlu R, et al. Antibacterial effects of curcumin: an in vitro minimum inhibitory concentration study. Toxicol Ind Health. 2013 Oct 21. [Epub ahead of print]. PMID: 24097361.

 

Kumar A, Dhamgaye S, Maurya IK, et al. Curcumin targets cell wall integrity via calcineurin mediated signaling in Candida albicans. Antimicrob Agents Chemother. 2013 Oct 21. [Epub ahead of print]. PMID: 24145527.

 

Yu T, Ji J, Guo YL. MST1 activation by curcumin mediates JNK activation, Foxo3a nuclear translocation and apoptosis in melanoma cells. Biochem Biophys Res Commun. 2013 Oct 14. [Epub ahead of print]. PMID: 24134840.

 

Narayanan N, Nargi D, Randolph C, et al. Liposome encapsulation of curcumin and resveratrol in combination reduces prostate cancer incidence in PTEN knockout mice. Int J Cancer. 2009Feb 6;125(1):1-8. PMID: 19326431.

 

Perry MC, Demeule M, Regina A, et al. Curcumin inhibits tumor growth and angiogenesis in glioblastoma xenografts. Mol Nutr Food Res. 2010 Aug;54(8):1192-1201. PMID: 20087857.

 

Martin RC, Aiyer HS, Malik D, Li Y. Effect on pro-inflammatory and antioxidant genes and bioavailable distribution of whole turmeric vs curcumin: similar root but different effects. Food Chem Toxicol. 2012 Feb;50(2):227-231. PMID: 22079310.

" Xi Not dangerous goods.

LKT C8069 Curcumin 10 g 56.5 Diarylheptanoid found in Zingiberaceae. (1E,6E)-1,7-Bis(4-hydroxy-3-methoxyphenyl)-1,6-heptadiene-3,5-dione Turmeric yellow 458-37-7 ≥97% curcuminoid content 368.38 C21H20O6 COC1=C(C=CC(=C1)C=CC(=O)CC(=O)C=CC2=CC(=C(C=C2)O)OC)O Ambient Ambient Insoluble in water.  Soluble in ethanol (10mg/mL), DMSO (74mg/mL), chloroform, acetone, DMF.  Soluble in 0.1 M NaOH to 3 mg/mL-do not store more than 12 hours. "Kawanishi N, Kato K, Takahashi M, et al. Curcumin attenuates oxidative stress following downhill running-induced muscle damage. Biochem Biophys Res Commun. 2013 Nov 22;441(3):573-8. PMID: 24184481.

 

Du WZ, Feng Y, Wang XF, et al. Curcumin Suppresses Malignant Glioma Cells Growth and Induces Apoptosis by Inhibition of SHH/GLI1 Signaling Pathway in Vitro and Vivo. CNS Neurosci Ther. 2013 Dec;19(12):926-36. PMID: 24165291.

 

Tian N, Li X, Luo Y, et al. Curcumin regulates the metabolism of low density lipoproteins by improving the C-to-U RNA editing efficiency of apolipoprotein B in primary rat hepatocytes. Mol Med Rep. 2013 Oct 24. [Epub ahead of print]. PMID: 24173373.

 

Wang Y, Yin H, Li J, et al. Amelioration of β-amyloid-induced cognitive dysfunction and hippocampal axon degeneration by curcumin is associated with suppression of CRMP-2 hyperphosphorylation. Neurosci Lett. 2013 Oct 21. [Epub ahead of print]. PMID: 24157857.

 

Antoine F, Simard JC, Girard D. Curcumin inhibits agent-induced human neutrophil functions in vitro and lipopolysaccharide-induced neutrophilic infiltration in vivo. Int Immunopharmacol. 2013 Oct 21. [Epub ahead of print]. PMID: 24157330.

 

Gunes H, Gulen D, Mutlu R, et al. Antibacterial effects of curcumin: an in vitro minimum inhibitory concentration study. Toxicol Ind Health. 2013 Oct 21. [Epub ahead of print]. PMID: 24097361.

 

Kumar A, Dhamgaye S, Maurya IK, et al. Curcumin targets cell wall integrity via calcineurin mediated signaling in Candida albicans. Antimicrob Agents Chemother. 2013 Oct 21. [Epub ahead of print]. PMID: 24145527.

 

Yu T, Ji J, Guo YL. MST1 activation by curcumin mediates JNK activation, Foxo3a nuclear translocation and apoptosis in melanoma cells. Biochem Biophys Res Commun. 2013 Oct 14. [Epub ahead of print]. PMID: 24134840.

 

Narayanan N, Nargi D, Randolph C, et al. Liposome encapsulation of curcumin and resveratrol in combination reduces prostate cancer incidence in PTEN knockout mice. Int J Cancer. 2009Feb 6;125(1):1-8. PMID: 19326431.

 

Perry MC, Demeule M, Regina A, et al. Curcumin inhibits tumor growth and angiogenesis in glioblastoma xenografts. Mol Nutr Food Res. 2010 Aug;54(8):1192-1201. PMID: 20087857.

 

Martin RC, Aiyer HS, Malik D, Li Y. Effect on pro-inflammatory and antioxidant genes and bioavailable distribution of whole turmeric vs curcumin: similar root but different effects. Food Chem Toxicol. 2012 Feb;50(2):227-231. PMID: 22079310.

" Xi Not dangerous goods.

LKT C8069 Curcumin 50 g 203.3 Diarylheptanoid found in Zingiberaceae. (1E,6E)-1,7-Bis(4-hydroxy-3-methoxyphenyl)-1,6-heptadiene-3,5-dione Turmeric yellow 458-37-7 ≥97% curcuminoid content 368.38 C21H20O6 COC1=C(C=CC(=C1)C=CC(=O)CC(=O)C=CC2=CC(=C(C=C2)O)OC)O Ambient Ambient Insoluble in water.  Soluble in ethanol (10mg/mL), DMSO (74mg/mL), chloroform, acetone, DMF.  Soluble in 0.1 M NaOH to 3 mg/mL-do not store more than 12 hours. "Kawanishi N, Kato K, Takahashi M, et al. Curcumin attenuates oxidative stress following downhill running-induced muscle damage. Biochem Biophys Res Commun. 2013 Nov 22;441(3):573-8. PMID: 24184481.

 

Du WZ, Feng Y, Wang XF, et al. Curcumin Suppresses Malignant Glioma Cells Growth and Induces Apoptosis by Inhibition of SHH/GLI1 Signaling Pathway in Vitro and Vivo. CNS Neurosci Ther. 2013 Dec;19(12):926-36. PMID: 24165291.

 

Tian N, Li X, Luo Y, et al. Curcumin regulates the metabolism of low density lipoproteins by improving the C-to-U RNA editing efficiency of apolipoprotein B in primary rat hepatocytes. Mol Med Rep. 2013 Oct 24. [Epub ahead of print]. PMID: 24173373.

 

Wang Y, Yin H, Li J, et al. Amelioration of β-amyloid-induced cognitive dysfunction and hippocampal axon degeneration by curcumin is associated with suppression of CRMP-2 hyperphosphorylation. Neurosci Lett. 2013 Oct 21. [Epub ahead of print]. PMID: 24157857.

 

Antoine F, Simard JC, Girard D. Curcumin inhibits agent-induced human neutrophil functions in vitro and lipopolysaccharide-induced neutrophilic infiltration in vivo. Int Immunopharmacol. 2013 Oct 21. [Epub ahead of print]. PMID: 24157330.

 

Gunes H, Gulen D, Mutlu R, et al. Antibacterial effects of curcumin: an in vitro minimum inhibitory concentration study. Toxicol Ind Health. 2013 Oct 21. [Epub ahead of print]. PMID: 24097361.

 

Kumar A, Dhamgaye S, Maurya IK, et al. Curcumin targets cell wall integrity via calcineurin mediated signaling in Candida albicans. Antimicrob Agents Chemother. 2013 Oct 21. [Epub ahead of print]. PMID: 24145527.

 

Yu T, Ji J, Guo YL. MST1 activation by curcumin mediates JNK activation, Foxo3a nuclear translocation and apoptosis in melanoma cells. Biochem Biophys Res Commun. 2013 Oct 14. [Epub ahead of print]. PMID: 24134840.

 

Narayanan N, Nargi D, Randolph C, et al. Liposome encapsulation of curcumin and resveratrol in combination reduces prostate cancer incidence in PTEN knockout mice. Int J Cancer. 2009Feb 6;125(1):1-8. PMID: 19326431.

 

Perry MC, Demeule M, Regina A, et al. Curcumin inhibits tumor growth and angiogenesis in glioblastoma xenografts. Mol Nutr Food Res. 2010 Aug;54(8):1192-1201. PMID: 20087857.

 

Martin RC, Aiyer HS, Malik D, Li Y. Effect on pro-inflammatory and antioxidant genes and bioavailable distribution of whole turmeric vs curcumin: similar root but different effects. Food Chem Toxicol. 2012 Feb;50(2):227-231. PMID: 22079310.

" Xi Not dangerous goods.

LKT C9677 Cyclocytidine Hydrochloride 1 g 73.3 Pyrimidine nucleoside analog; DNA synthesis inhibitor. 2,2'-Anhydro-1-β-D-arabinofuranosylcytosine hydrochloride Ancitabine hydrochloride; O-2,2'-Cyclocytidine monohydrochloride 10212-25-6 ≥98% 261.66 C9H11N3O4 HCl C1=CN2C3C(C(C(O3)CO)O)OC2=NC1=N.Cl Ambient Ambient Soluble in water, micro-soluble alcohol "Thomopoulos GN, Garrett JR, Proctor GB. Ultrastructural histochemical studies of secretory granule replenishment in rat submandibular granular tubules after cyclocytidine-induced secretion. J Submicrosc Cytol Pathol. 2002 Jul;34(3):279-89. PMID: 12408361.

 

Chen Z, Song J, Chen K. Anti-herpes simplex virus action of combined therapy with cyclocytidine and ganciclovir. Zhonghua Yan Ke Za Zhi. 1996 Jan;32(1):25-8. PMID: 8758385.

 

Nakamura K, Eizuru Y, Kumura K, et al. Antiviral effect of antileukemic drugs N4-behenoyl-1-beta-D-arabinofuranosylcytosine (BH-AC) and 2,2'-anhydro-1-beta-D-arabinofuranosylcytosine (cyclo-C) against human cytomegalovirus. J Med Virol. 1990 Jun;31(2):141-7. PMID: 1696958.

 

Movassaghi N, Higgins G, Pyesmany A, et al. Evaluation of cyclocytidine in reinduction and maintenance therapy of children with acute nonlymphocytic leukemia previously treated with cytosine arabinoside: a report from Children's Cancer Study Group. Med Pediatr Oncol. 1984;12(5):352-6. PMID: 6208468.

" Not dangerous goods.

LKT C9677 Cyclocytidine Hydrochloride 5 g 271.8 Pyrimidine nucleoside analog; DNA synthesis inhibitor. 2,2'-Anhydro-1-β-D-arabinofuranosylcytosine hydrochloride Ancitabine hydrochloride; O-2,2'-Cyclocytidine monohydrochloride 10212-25-6 ≥98% 261.66 C9H11N3O4 HCl C1=CN2C3C(C(C(O3)CO)O)OC2=NC1=N.Cl Ambient Ambient Soluble in water, micro-soluble alcohol "Thomopoulos GN, Garrett JR, Proctor GB. Ultrastructural histochemical studies of secretory granule replenishment in rat submandibular granular tubules after cyclocytidine-induced secretion. J Submicrosc Cytol Pathol. 2002 Jul;34(3):279-89. PMID: 12408361.

 

Chen Z, Song J, Chen K. Anti-herpes simplex virus action of combined therapy with cyclocytidine and ganciclovir. Zhonghua Yan Ke Za Zhi. 1996 Jan;32(1):25-8. PMID: 8758385.

 

Nakamura K, Eizuru Y, Kumura K, et al. Antiviral effect of antileukemic drugs N4-behenoyl-1-beta-D-arabinofuranosylcytosine (BH-AC) and 2,2'-anhydro-1-beta-D-arabinofuranosylcytosine (cyclo-C) against human cytomegalovirus. J Med Virol. 1990 Jun;31(2):141-7. PMID: 1696958.

 

Movassaghi N, Higgins G, Pyesmany A, et al. Evaluation of cyclocytidine in reinduction and maintenance therapy of children with acute nonlymphocytic leukemia previously treated with cytosine arabinoside: a report from Children's Cancer Study Group. Med Pediatr Oncol. 1984;12(5):352-6. PMID: 6208468.

" Not dangerous goods.

LKT C9609 Cyclophosphamide Monohydrate 1 g 58.2 Nitrogen mustard, DNA alkylator. N,N-Bis(2-chloroethyl)tetrahydro-2H-1,3,2-ox- azaphosphorin-2-amine 2 oxide monohydrate Cycloblastin; Cyclostin; Cytoxan; Endoxan 6055-19-2 ≥98% 279.1 C7H15Cl2N2O2P H2O C1CNP(=O)(OC1)N(CCCl)CCCl.O Ambient 4°C Soluble in water.  Slightly soluble in ethanol. "Sistigu A, Viaud S, Chaput N, et al. Immunomodulatory effects of cyclophosphamide and implementations for vaccine design. Semin Immunopathol. 2011 Jul;33(4):369-83. PMID: 21611872.

 

Makhani N, Gorman MP, Branson HM, et al. Cyclophosphamide therapy in pediatric multiple sclerosis. Neurology. 2009 Jun 16;72(24):2076-82. PMID: 19439723.

 

Hall AG, Tilby MJ. Mechanisms of action of, and modes of resistance to, alkylating agents used in the treatment of haematological malignancies. Blood Rev. 1992 Sep;6(3):163-73. PMID: 1422285.

" Xi, T, Repr., Carc. "UN number: 3464     Class:  6.1     Packing group:  III  

Proper shipping name:  Organophosphorus compound, solid, toxic, n.o.s. (Cyclophosphamide monohydrate)

Reportable quantity (RQ): 10 lbs.,  Marine pollutant: No,  Poison inhalation hazard:  No"

LKT C9609 Cyclophosphamide Monohydrate 5 g 175.5 Nitrogen mustard, DNA alkylator. N,N-Bis(2-chloroethyl)tetrahydro-2H-1,3,2-ox- azaphosphorin-2-amine 2 oxide monohydrate Cycloblastin; Cyclostin; Cytoxan; Endoxan 6055-19-2 ≥98% 279.1 C7H15Cl2N2O2P H2O C1CNP(=O)(OC1)N(CCCl)CCCl.O Ambient 4°C Soluble in water.  Slightly soluble in ethanol. "Sistigu A, Viaud S, Chaput N, et al. Immunomodulatory effects of cyclophosphamide and implementations for vaccine design. Semin Immunopathol. 2011 Jul;33(4):369-83. PMID: 21611872.

 

Makhani N, Gorman MP, Branson HM, et al. Cyclophosphamide therapy in pediatric multiple sclerosis. Neurology. 2009 Jun 16;72(24):2076-82. PMID: 19439723.

 

Hall AG, Tilby MJ. Mechanisms of action of, and modes of resistance to, alkylating agents used in the treatment of haematological malignancies. Blood Rev. 1992 Sep;6(3):163-73. PMID: 1422285.

" Xi, T, Repr., Carc. "UN number: 3464     Class:  6.1     Packing group:  III  

Proper shipping name:  Organophosphorus compound, solid, toxic, n.o.s. (Cyclophosphamide monohydrate)

Reportable quantity (RQ): 10 lbs.,  Marine pollutant: No,  Poison inhalation hazard:  No"

LKT C9673 Cysteamine Hydrochloride 25 g 61.1 Aminothiol, CoA component; ulcer inducer. 2-Aminoethanothiol hydrochloride Mercaptamine; Decarboxycysteine; MEA; Mercamine; Becaptan 156-57-0 ≥98% 113.61 C2H7NS HCl C(CS)N.Cl Ambient Ambient Soluble in water or ethanol. "Khomenko T, Deng X, Ahluwalia A, et al. STAT3 and importins are novel mediators of early molecular and cellular responses in experimental duodenal ulceration. Dig Dis Sci. 2014 Feb;59(2):297-306. PMID: 24385009.

 

Fujisawa T, Rubin B, Suzuki A, et al. Cysteamine suppresses invasion, metastasis and prolongs survival by inhibiting matrix metalloproteinases in a mouse model of human pancreatic cancer. PLoS One. 2012;7(4):e34437. PMID: 22532830.

 

Shieh CH, Hong CJ, Huang YH, et al. Potential antidepressant properties of cysteamine on hippocampal BDNF levels and behavioral despair in mice. Prog Neuropsychopharmacol Biol Psychiatry. 2008 Aug 1;32(6):1590-4. PMID: 18582526.

 

Pae CU, Lee C, Paik IH. Therapeutic possibilities of cysteamine in the treatment of schizophrenia. Med Hypotheses. 2007;69(1):199-202. PMID: 17166669.

 

Mao Z, Choo YS, Lesort M. Cystamine and cysteamine prevent 3-NP-induced mitochondrial depolarization of Huntington's disease knock-in striatal cells. Eur J Neurosci. 2006 Apr;23(7):1701-10. PMID: 16623826.

" Xn "UN number: 3335     Class:  9

Proper shipping name:  A Aviation regulated solid, n.o.s. (Mercaptamine hydrochloride)

Reportable quantity (RQ):     Poison inhalation hazard:  No."

LKT C9673 Cysteamine Hydrochloride 100 g 200.2 Aminothiol, CoA component; ulcer inducer. 2-Aminoethanothiol hydrochloride Mercaptamine; Decarboxycysteine; MEA; Mercamine; Becaptan 156-57-0 ≥98% 113.61 C2H7NS HCl C(CS)N.Cl Ambient Ambient Soluble in water or ethanol. "Khomenko T, Deng X, Ahluwalia A, et al. STAT3 and importins are novel mediators of early molecular and cellular responses in experimental duodenal ulceration. Dig Dis Sci. 2014 Feb;59(2):297-306. PMID: 24385009.

 

Fujisawa T, Rubin B, Suzuki A, et al. Cysteamine suppresses invasion, metastasis and prolongs survival by inhibiting matrix metalloproteinases in a mouse model of human pancreatic cancer. PLoS One. 2012;7(4):e34437. PMID: 22532830.

 

Shieh CH, Hong CJ, Huang YH, et al. Potential antidepressant properties of cysteamine on hippocampal BDNF levels and behavioral despair in mice. Prog Neuropsychopharmacol Biol Psychiatry. 2008 Aug 1;32(6):1590-4. PMID: 18582526.

 

Pae CU, Lee C, Paik IH. Therapeutic possibilities of cysteamine in the treatment of schizophrenia. Med Hypotheses. 2007;69(1):199-202. PMID: 17166669.

 

Mao Z, Choo YS, Lesort M. Cystamine and cysteamine prevent 3-NP-induced mitochondrial depolarization of Huntington's disease knock-in striatal cells. Eur J Neurosci. 2006 Apr;23(7):1701-10. PMID: 16623826.

" Xn "UN number: 3335     Class:  9

Proper shipping name:  A Aviation regulated solid, n.o.s. (Mercaptamine hydrochloride)

Reportable quantity (RQ):     Poison inhalation hazard:  No."

LKT D0032 Daidzein 250 mg 68.6 Phytoestrogen, isoflavone found in various plant sources such as soy. 7-Hydroxy-3-(4-hydroxyphenyl)-4H-1-benzopyran-4-one 7,4'-Dihydroxyisoflavone 486-66-8 ≥97% 254.24 C15H10O4 C1=CC(=CC=C1C2=COC3=C(C2=O)C=CC(=C3)O)O Ambient Ambient Soluble in ethanol or ether. "Li HY, Pan L, Ke YS, et al. Daidzein suppresses pro-inflammatory chemokine Cxcl2 transcription in TNF-α-stimulated murine lung epithelial cells via depressing PARP-1 activity. Acta Pharmacol Sin. 2014 Apr;35(4):496-503. PMID: 24632845.

 

Zhao D, Shi Y, Dang Y, et al. Daidzein stimulates collagen synthesis by activating the TGF-β/smad signal pathway. Australas J Dermatol. 2014 Mar 19. [Epub ahead of print]. PMID: 24645968.

 

Park HJ, Jeon YK, You DH, et al. Daidzein causes cytochrome c-mediated apoptosis via the Bcl-2 family in human hepatic cancer cells. Food Chem Toxicol. 2013 Oct;60:542-9. PMID: 23959101.

 

Yanagihara K, Takigahira M, Mihara K, et al. Inhibitory effects of isoflavones on tumor growth and cachexia in newly established cachectic mouse models carrying human stomach cancers. Nutr Cancer. 2013;65(4):578-89. PMID: 23659450.

 

Yang SH, Liao CC, Chen Y, et al. Daidzein induces neuritogenesis in DRG neuronal cultures. J Biomed Sci. 2012 Aug 29;19:80. PMID: 22931352.

 

Tyagi AM, Srivastava K, Sharan K, et al. Daidzein prevents the increase in CD4+CD28null T cells and B lymphopoesis in ovariectomized mice: a key mechanism for anti-osteoclastogenic effect. PLoS One. 2011;6(6):e21216. PMID: 21731677.

 

Kim MH, Park JS, Seo MS, et al. Genistein and daidzein repress adipogenic differentiation of human adipose tissue-derived mesenchymal stem cells via Wnt/β-catenin signalling or lipolysis. Cell Prolif. 2010 Dec;43(6):594-605. PMID: 21039998.

 

Mishra P, Kar A, Kale RK. Prevention of chemically induced mammary tumorigenesis by daidzein in pre-pubertal rats: the role of peroxidative damage and antioxidative enzymes. Mol Cell Biochem. 2009 May;325(1-2):149-57. PMID: 19214712.

 

Yokoyama S, Niwa T, Osawa T, Suzuki T. Characterization of an O-desmethylangolensin-producing bacterium isolated from human feces. Arch Microbiol. 2010 Jan;192(1):15-22. PMID: 19904524.

" Xi Not dangerous goods.

LKT D0032 Daidzein 1 g 212.7 Phytoestrogen, isoflavone found in various plant sources such as soy. 7-Hydroxy-3-(4-hydroxyphenyl)-4H-1-benzopyran-4-one 7,4'-Dihydroxyisoflavone 486-66-8 ≥97% 254.24 C15H10O4 C1=CC(=CC=C1C2=COC3=C(C2=O)C=CC(=C3)O)O Ambient Ambient Soluble in ethanol or ether. "Li HY, Pan L, Ke YS, et al. Daidzein suppresses pro-inflammatory chemokine Cxcl2 transcription in TNF-α-stimulated murine lung epithelial cells via depressing PARP-1 activity. Acta Pharmacol Sin. 2014 Apr;35(4):496-503. PMID: 24632845.

 

Zhao D, Shi Y, Dang Y, et al. Daidzein stimulates collagen synthesis by activating the TGF-β/smad signal pathway. Australas J Dermatol. 2014 Mar 19. [Epub ahead of print]. PMID: 24645968.

 

Park HJ, Jeon YK, You DH, et al. Daidzein causes cytochrome c-mediated apoptosis via the Bcl-2 family in human hepatic cancer cells. Food Chem Toxicol. 2013 Oct;60:542-9. PMID: 23959101.

 

Yanagihara K, Takigahira M, Mihara K, et al. Inhibitory effects of isoflavones on tumor growth and cachexia in newly established cachectic mouse models carrying human stomach cancers. Nutr Cancer. 2013;65(4):578-89. PMID: 23659450.

 

Yang SH, Liao CC, Chen Y, et al. Daidzein induces neuritogenesis in DRG neuronal cultures. J Biomed Sci. 2012 Aug 29;19:80. PMID: 22931352.

 

Tyagi AM, Srivastava K, Sharan K, et al. Daidzein prevents the increase in CD4+CD28null T cells and B lymphopoesis in ovariectomized mice: a key mechanism for anti-osteoclastogenic effect. PLoS One. 2011;6(6):e21216. PMID: 21731677.

 

Kim MH, Park JS, Seo MS, et al. Genistein and daidzein repress adipogenic differentiation of human adipose tissue-derived mesenchymal stem cells via Wnt/β-catenin signalling or lipolysis. Cell Prolif. 2010 Dec;43(6):594-605. PMID: 21039998.

 

Mishra P, Kar A, Kale RK. Prevention of chemically induced mammary tumorigenesis by daidzein in pre-pubertal rats: the role of peroxidative damage and antioxidative enzymes. Mol Cell Biochem. 2009 May;325(1-2):149-57. PMID: 19214712.

 

Yokoyama S, Niwa T, Osawa T, Suzuki T. Characterization of an O-desmethylangolensin-producing bacterium isolated from human feces. Arch Microbiol. 2010 Jan;192(1):15-22. PMID: 19904524.

" Xi Not dangerous goods.

LKT D0032 Daidzein 5 g 420.2 Phytoestrogen, isoflavone found in various plant sources such as soy. 7-Hydroxy-3-(4-hydroxyphenyl)-4H-1-benzopyran-4-one 7,4'-Dihydroxyisoflavone 486-66-8 ≥97% 254.24 C15H10O4 C1=CC(=CC=C1C2=COC3=C(C2=O)C=CC(=C3)O)O Ambient Ambient Soluble in ethanol or ether. "Li HY, Pan L, Ke YS, et al. Daidzein suppresses pro-inflammatory chemokine Cxcl2 transcription in TNF-α-stimulated murine lung epithelial cells via depressing PARP-1 activity. Acta Pharmacol Sin. 2014 Apr;35(4):496-503. PMID: 24632845.

 

Zhao D, Shi Y, Dang Y, et al. Daidzein stimulates collagen synthesis by activating the TGF-β/smad signal pathway. Australas J Dermatol. 2014 Mar 19. [Epub ahead of print]. PMID: 24645968.

 

Park HJ, Jeon YK, You DH, et al. Daidzein causes cytochrome c-mediated apoptosis via the Bcl-2 family in human hepatic cancer cells. Food Chem Toxicol. 2013 Oct;60:542-9. PMID: 23959101.

 

Yanagihara K, Takigahira M, Mihara K, et al. Inhibitory effects of isoflavones on tumor growth and cachexia in newly established cachectic mouse models carrying human stomach cancers. Nutr Cancer. 2013;65(4):578-89. PMID: 23659450.

 

Yang SH, Liao CC, Chen Y, et al. Daidzein induces neuritogenesis in DRG neuronal cultures. J Biomed Sci. 2012 Aug 29;19:80. PMID: 22931352.

 

Tyagi AM, Srivastava K, Sharan K, et al. Daidzein prevents the increase in CD4+CD28null T cells and B lymphopoesis in ovariectomized mice: a key mechanism for anti-osteoclastogenic effect. PLoS One. 2011;6(6):e21216. PMID: 21731677.

 

Kim MH, Park JS, Seo MS, et al. Genistein and daidzein repress adipogenic differentiation of human adipose tissue-derived mesenchymal stem cells via Wnt/β-catenin signalling or lipolysis. Cell Prolif. 2010 Dec;43(6):594-605. PMID: 21039998.

 

Mishra P, Kar A, Kale RK. Prevention of chemically induced mammary tumorigenesis by daidzein in pre-pubertal rats: the role of peroxidative damage and antioxidative enzymes. Mol Cell Biochem. 2009 May;325(1-2):149-57. PMID: 19214712.

 

Yokoyama S, Niwa T, Osawa T, Suzuki T. Characterization of an O-desmethylangolensin-producing bacterium isolated from human feces. Arch Microbiol. 2010 Jan;192(1):15-22. PMID: 19904524.

" Xi Not dangerous goods.

LKT D0182 Daunorubicin Hydrochloride 10 mg 108.8 Anthracycline, DNA intercalator; topoisomerase II inhibitor. (8S-cis)-8-Acetyl-10-[(3-amino-2,3,6-trideoxy-α-L- lyxo-hexopyranosyl)oxy]-7,8,9,10-tetrahydro-6,8,11- trihydroxy-1-methoxy-5,12-naphthacenedione Daunomycin; Leukaemomycin C; Rubidomycin; RP-13057; Cerubidin. 23541-50-6 ≥98% 564 C27H29NO10HCl CC1C(C(CC(O1)OC2CC(CC3=C(C4=C(C(=C23)O)C(=O)C5=C(C4=O)C=CC=C5OC)O)(C(=O)C)O)N)O.Cl Ambient 4°C Soluble in water or ethanol. "Pang B, Qiao X, Janssen L, et al. Drug-induced histone eviction from open chromatin contributes to the chemotherapeutic effects of doxorubicin. Nat Commun. 2013;4:1908. PMID: 23715267.

 

Quigley GJ, Wang AH, Ughetto G, et al. Molecular structure of an anticancer drug-DNA complex: daunomycin plus d(CpGpTpApCpG). Proc Natl Acad Sci U S A. 1980 Dec;77(12):7204-8. PMID: 6938965.

" Xn "UN number: 2811     Class:  6.1     Packing group:  III

Proper shipping name:  Toxic solids, organic, n.o.s. (Daunorubicin hydrochloride)

Marine pollutant:  No     Poison inhalation hazard:  No"

LKT D0182 Daunorubicin Hydrochloride 50 mg 373.7 Anthracycline, DNA intercalator; topoisomerase II inhibitor. (8S-cis)-8-Acetyl-10-[(3-amino-2,3,6-trideoxy-α-L- lyxo-hexopyranosyl)oxy]-7,8,9,10-tetrahydro-6,8,11- trihydroxy-1-methoxy-5,12-naphthacenedione Daunomycin; Leukaemomycin C; Rubidomycin; RP-13057; Cerubidin. 23541-50-6 ≥98% 564 C27H29NO10HCl CC1C(C(CC(O1)OC2CC(CC3=C(C4=C(C(=C23)O)C(=O)C5=C(C4=O)C=CC=C5OC)O)(C(=O)C)O)N)O.Cl Ambient 4°C Soluble in water or ethanol. "Pang B, Qiao X, Janssen L, et al. Drug-induced histone eviction from open chromatin contributes to the chemotherapeutic effects of doxorubicin. Nat Commun. 2013;4:1908. PMID: 23715267.

 

Quigley GJ, Wang AH, Ughetto G, et al. Molecular structure of an anticancer drug-DNA complex: daunomycin plus d(CpGpTpApCpG). Proc Natl Acad Sci U S A. 1980 Dec;77(12):7204-8. PMID: 6938965.

" Xn "UN number: 2811     Class:  6.1     Packing group:  III

Proper shipping name:  Toxic solids, organic, n.o.s. (Daunorubicin hydrochloride)

Marine pollutant:  No     Poison inhalation hazard:  No"

LKT D0182 Daunorubicin Hydrochloride 100 mg 652.3 Anthracycline, DNA intercalator; topoisomerase II inhibitor. (8S-cis)-8-Acetyl-10-[(3-amino-2,3,6-trideoxy-α-L- lyxo-hexopyranosyl)oxy]-7,8,9,10-tetrahydro-6,8,11- trihydroxy-1-methoxy-5,12-naphthacenedione Daunomycin; Leukaemomycin C; Rubidomycin; RP-13057; Cerubidin. 23541-50-6 ≥98% 564 C27H29NO10HCl CC1C(C(CC(O1)OC2CC(CC3=C(C4=C(C(=C23)O)C(=O)C5=C(C4=O)C=CC=C5OC)O)(C(=O)C)O)N)O.Cl Ambient 4°C Soluble in water or ethanol. "Pang B, Qiao X, Janssen L, et al. Drug-induced histone eviction from open chromatin contributes to the chemotherapeutic effects of doxorubicin. Nat Commun. 2013;4:1908. PMID: 23715267.

 

Quigley GJ, Wang AH, Ughetto G, et al. Molecular structure of an anticancer drug-DNA complex: daunomycin plus d(CpGpTpApCpG). Proc Natl Acad Sci U S A. 1980 Dec;77(12):7204-8. PMID: 6938965.

" Xn "UN number: 2811     Class:  6.1     Packing group:  III

Proper shipping name:  Toxic solids, organic, n.o.s. (Daunorubicin hydrochloride)

Marine pollutant:  No     Poison inhalation hazard:  No"

LKT D1629 Dehydroepiandrosterone 5 g 62.2 Endogenous steroid hormone; ERβ, NMDA, σ1 agonist, ERα and AR partial agonist, GABA-A antagonist. (3β)-3-Hydroxyandrost-5-en-17-one Prasterone; DHEA; Dehydroepiandosterone 53-43-0 ≥98% 288.42 C19H28O2 CC12CCC3C(C1CCC2=O)CC=C4C3(CCC(C4)O)C Ambient Ambient Soluble in ethanol or DMSO.  Insoluble in water. "do Vale S, Selinger L, Martins JM, et al. The relationship between dehydroepiandrosterone (DHEA), working memory and distraction--a behavioral and electrophysiological approach. PLoS One. 2014 Aug 8;9(8):e104869. PMID: 25105970.

 

Ortega-Calderón YN, López-Marure R. Dehydroepiandrosterone inhibits proliferation and suppresses migration of human cervical cancer cell lines. Anticancer Res. 2014 Aug;34(8):4039-44. PMID: 25075027.

 

Xu L, Xiang X, Ji X, et al. Effects and mechanism of dehydroepiandrosterone on epithelial-mesenchymal transition in bronchial epithelial cells. Exp Lung Res. 2014 Jun;40(5):211-21. PMID: 24784499.

 

Eleawa S, Bin-Jaliah I, Alkhateeb M, et al. The impact of dehydroepiandrosterone on indomethacin-induced gastric lesions in rats. Acta Physiol Hung. 2014 Mar;101(1):77-87. PMID: 24631796.

 

Engdahl C, Lagerquist MK, Stubelius A, et al. Role of androgen and estrogen receptors for the action of dehydroepiandrosterone (DHEA). Endocrinology. 2014 Mar;155(3):889-96. PMID: 24424045.

 

Neunzig J, Bernhardt R. Dehydroepiandrosterone sulfate (DHEAS) stimulates the first step in the biosynthesis of steroid hormones. PLoS One. 2014 Feb 21;9(2):e89727. PMID: 24586990.

 

Espinoza J, Montaño LM, Perusquía M. Nongenomic bronchodilating action elicited by dehydroepiandrosterone (DHEA) in a guinea pig asthma model. J Steroid Biochem Mol Biol. 2013 Nov;138:174-82. PMID: 23727130.

 

Mishra M, Singh R, Mukherjee S, et al. Dehydroepiandrosterone's antiepileptic action in FeCl3-induced epileptogenesis involves upregulation of glutamate transporters. Epilepsy Res. 2013 Sep;106(1-2):83-91. PMID: 23891458.

" Xi Not dangerous goods.

LKT D1629 Dehydroepiandrosterone 25 g 254.2 Endogenous steroid hormone; ERβ, NMDA, σ1 agonist, ERα and AR partial agonist, GABA-A antagonist. (3β)-3-Hydroxyandrost-5-en-17-one Prasterone; DHEA; Dehydroepiandosterone 53-43-0 ≥98% 288.42 C19H28O2 CC12CCC3C(C1CCC2=O)CC=C4C3(CCC(C4)O)C Ambient Ambient Soluble in ethanol or DMSO.  Insoluble in water. "do Vale S, Selinger L, Martins JM, et al. The relationship between dehydroepiandrosterone (DHEA), working memory and distraction--a behavioral and electrophysiological approach. PLoS One. 2014 Aug 8;9(8):e104869. PMID: 25105970.

 

Ortega-Calderón YN, López-Marure R. Dehydroepiandrosterone inhibits proliferation and suppresses migration of human cervical cancer cell lines. Anticancer Res. 2014 Aug;34(8):4039-44. PMID: 25075027.

 

Xu L, Xiang X, Ji X, et al. Effects and mechanism of dehydroepiandrosterone on epithelial-mesenchymal transition in bronchial epithelial cells. Exp Lung Res. 2014 Jun;40(5):211-21. PMID: 24784499.

 

Eleawa S, Bin-Jaliah I, Alkhateeb M, et al. The impact of dehydroepiandrosterone on indomethacin-induced gastric lesions in rats. Acta Physiol Hung. 2014 Mar;101(1):77-87. PMID: 24631796.

 

Engdahl C, Lagerquist MK, Stubelius A, et al. Role of androgen and estrogen receptors for the action of dehydroepiandrosterone (DHEA). Endocrinology. 2014 Mar;155(3):889-96. PMID: 24424045.

 

Neunzig J, Bernhardt R. Dehydroepiandrosterone sulfate (DHEAS) stimulates the first step in the biosynthesis of steroid hormones. PLoS One. 2014 Feb 21;9(2):e89727. PMID: 24586990.

 

Espinoza J, Montaño LM, Perusquía M. Nongenomic bronchodilating action elicited by dehydroepiandrosterone (DHEA) in a guinea pig asthma model. J Steroid Biochem Mol Biol. 2013 Nov;138:174-82. PMID: 23727130.

 

Mishra M, Singh R, Mukherjee S, et al. Dehydroepiandrosterone's antiepileptic action in FeCl3-induced epileptogenesis involves upregulation of glutamate transporters. Epilepsy Res. 2013 Sep;106(1-2):83-91. PMID: 23891458.

" Xi Not dangerous goods.

LKT D1629 Dehydroepiandrosterone 100 g 753.5 Endogenous steroid hormone; ERβ, NMDA, σ1 agonist, ERα and AR partial agonist, GABA-A antagonist. (3β)-3-Hydroxyandrost-5-en-17-one Prasterone; DHEA; Dehydroepiandosterone 53-43-0 ≥98% 288.42 C19H28O2 CC12CCC3C(C1CCC2=O)CC=C4C3(CCC(C4)O)C Ambient Ambient Soluble in ethanol or DMSO.  Insoluble in water. "do Vale S, Selinger L, Martins JM, et al. The relationship between dehydroepiandrosterone (DHEA), working memory and distraction--a behavioral and electrophysiological approach. PLoS One. 2014 Aug 8;9(8):e104869. PMID: 25105970.

 

Ortega-Calderón YN, López-Marure R. Dehydroepiandrosterone inhibits proliferation and suppresses migration of human cervical cancer cell lines. Anticancer Res. 2014 Aug;34(8):4039-44. PMID: 25075027.

 

Xu L, Xiang X, Ji X, et al. Effects and mechanism of dehydroepiandrosterone on epithelial-mesenchymal transition in bronchial epithelial cells. Exp Lung Res. 2014 Jun;40(5):211-21. PMID: 24784499.

 

Eleawa S, Bin-Jaliah I, Alkhateeb M, et al. The impact of dehydroepiandrosterone on indomethacin-induced gastric lesions in rats. Acta Physiol Hung. 2014 Mar;101(1):77-87. PMID: 24631796.

 

Engdahl C, Lagerquist MK, Stubelius A, et al. Role of androgen and estrogen receptors for the action of dehydroepiandrosterone (DHEA). Endocrinology. 2014 Mar;155(3):889-96. PMID: 24424045.

 

Neunzig J, Bernhardt R. Dehydroepiandrosterone sulfate (DHEAS) stimulates the first step in the biosynthesis of steroid hormones. PLoS One. 2014 Feb 21;9(2):e89727. PMID: 24586990.

 

Espinoza J, Montaño LM, Perusquía M. Nongenomic bronchodilating action elicited by dehydroepiandrosterone (DHEA) in a guinea pig asthma model. J Steroid Biochem Mol Biol. 2013 Nov;138:174-82. PMID: 23727130.

 

Mishra M, Singh R, Mukherjee S, et al. Dehydroepiandrosterone's antiepileptic action in FeCl3-induced epileptogenesis involves upregulation of glutamate transporters. Epilepsy Res. 2013 Sep;106(1-2):83-91. PMID: 23891458.

" Xi Not dangerous goods.

LKT D1757 L-Deoxyalliin 1 g 151.9 Organosulfur found in garlic. S-Allyl-L-cysteine L-Cysteine, S-2-propenyl-; S-Allylcysteine 21593-77-1 ≥98% 161.22 C6H11NO2S C=CCSCC(C(=O)O)N Ambient 4°C Soluble in water.  "Spera MB, Quintão FA, Ferraresi DK, et al. Palladium(II) complex with S-allyl-L-cysteine: new solid-state NMR spectroscopic measurements, molecular modeling and antibacterial assays. Spectrochim Acta A Mol Biomol Spectrosc. 2011 Jan;78(1):313-8. PMID: 21050807.

 

Arnault I, Christidès JP, Mandon N, et al. High-performance ion-pair chromatography method for simultaneous analysis of alliin, deoxyalliin, allicin and dipeptide precursors in garlic products using multiple mass spectrometry and UV detection. J Chromatogr A. 2003 Mar 28;991(1):69-75. PMID: 12703902.

" Not dangerous goods.

LKT D1757 L-Deoxyalliin 5 g 611.5 Organosulfur found in garlic. S-Allyl-L-cysteine L-Cysteine, S-2-propenyl-; S-Allylcysteine 21593-77-1 ≥98% 161.22 C6H11NO2S C=CCSCC(C(=O)O)N Ambient 4°C Soluble in water.  "Spera MB, Quintão FA, Ferraresi DK, et al. Palladium(II) complex with S-allyl-L-cysteine: new solid-state NMR spectroscopic measurements, molecular modeling and antibacterial assays. Spectrochim Acta A Mol Biomol Spectrosc. 2011 Jan;78(1):313-8. PMID: 21050807.

 

Arnault I, Christidès JP, Mandon N, et al. High-performance ion-pair chromatography method for simultaneous analysis of alliin, deoxyalliin, allicin and dipeptide precursors in garlic products using multiple mass spectrometry and UV detection. J Chromatogr A. 2003 Mar 28;991(1):69-75. PMID: 12703902.

" Not dangerous goods.

LKT D1693 Dexamethasone 100 mg 66.7 Glucocorticoid agonist. (11β,16α)-9-Fluoro-11,17,21-trihydro-16-methyl- pregna-1,4-diene-3,20-dione Decadron; Maxidex 50-02-2 ≥97% 392.46 C22FH29O5 CC1CC2C3CCC4=CC(=O)C=CC4(C3(C(CC2(C1(C(=O)CO)O)C)O)F)C Ambient Ambient Soluble in DMF (25 mg/ml) and DMSO (25 mg/ml. Sparingly soluble in ethanol. Insoluble in water. "Bartneck M, Peters FM, Warzecha KT, et al. Liposomal encapsulation of dexamethasone modulates cytotoxicity, inflammatory cytokine response, and migratory properties of primary human macrophages. Nanomedicine. 2014 Mar 7. [Epub ahead of print]. PMID: 24607939.

 

Ni Z, Tang J, Cai Z, et al. A new pathway of glucocorticoid action for asthma treatment through the regulation of PTEN expression. Respir Res. 2011 Apr 14;12:47. PMID: 21489309.

 

Morgan G. Future drug developments in multiple myeloma: an overview of novel lenalidomide-based combination therapies. Blood Rev. 2010 Nov;24 Suppl 1:S27-32. PMID: 21126634.

" Carc, Xn Not dangerous goods.

LKT D1693 Dexamethasone 500 mg 194.8 Glucocorticoid agonist. (11β,16α)-9-Fluoro-11,17,21-trihydro-16-methyl- pregna-1,4-diene-3,20-dione Decadron; Maxidex 50-02-2 ≥97% 392.46 C22FH29O5 CC1CC2C3CCC4=CC(=O)C=CC4(C3(C(CC2(C1(C(=O)CO)O)C)O)F)C Ambient Ambient Soluble in DMF (25 mg/ml) and DMSO (25 mg/ml. Sparingly soluble in ethanol. Insoluble in water. "Bartneck M, Peters FM, Warzecha KT, et al. Liposomal encapsulation of dexamethasone modulates cytotoxicity, inflammatory cytokine response, and migratory properties of primary human macrophages. Nanomedicine. 2014 Mar 7. [Epub ahead of print]. PMID: 24607939.

 

Ni Z, Tang J, Cai Z, et al. A new pathway of glucocorticoid action for asthma treatment through the regulation of PTEN expression. Respir Res. 2011 Apr 14;12:47. PMID: 21489309.

 

Morgan G. Future drug developments in multiple myeloma: an overview of novel lenalidomide-based combination therapies. Blood Rev. 2010 Nov;24 Suppl 1:S27-32. PMID: 21126634.

" Carc, Xn Not dangerous goods.

LKT D1693 Dexamethasone 1 g 300.8 Glucocorticoid agonist. (11β,16α)-9-Fluoro-11,17,21-trihydro-16-methyl- pregna-1,4-diene-3,20-dione Decadron; Maxidex 50-02-2 ≥97% 392.46 C22FH29O5 CC1CC2C3CCC4=CC(=O)C=CC4(C3(C(CC2(C1(C(=O)CO)O)C)O)F)C Ambient Ambient Soluble in DMF (25 mg/ml) and DMSO (25 mg/ml. Sparingly soluble in ethanol. Insoluble in water. "Bartneck M, Peters FM, Warzecha KT, et al. Liposomal encapsulation of dexamethasone modulates cytotoxicity, inflammatory cytokine response, and migratory properties of primary human macrophages. Nanomedicine. 2014 Mar 7. [Epub ahead of print]. PMID: 24607939.

 

Ni Z, Tang J, Cai Z, et al. A new pathway of glucocorticoid action for asthma treatment through the regulation of PTEN expression. Respir Res. 2011 Apr 14;12:47. PMID: 21489309.

 

Morgan G. Future drug developments in multiple myeloma: an overview of novel lenalidomide-based combination therapies. Blood Rev. 2010 Nov;24 Suppl 1:S27-32. PMID: 21126634.

" Carc, Xn Not dangerous goods.

LKT D3201 Diallyl Sulfide 25 ml 89.7 Organosulfur found in garlic. Di-2-propenyl sulfide 2-Propenyl sulphide; 3,3-Thiobis(1-propene); Diallyl monosulfide; Diallyl thioether;  Allyl monosulfide; Allyl sulfide 592-88-1 ≥97% 114.21 C6H10S C=CCSCC=C Ambient Ambient Insoluble in water. "McCaskill ML, Rogan E, D Thomas R. Diallyl sulfide inhibits diethylstilbestrol induced DNA damage in human breast epithelial cells (MCF-10A). Steroids. 2014 Sep 30. [Epub ahead of print]. PMID: 25278253.

 

Ho CY, Weng CJ, Jhang JJ, et al. Diallyl sulfide as a potential dietary agent to reduce TNF-α- and histamine-induced proinflammatory responses in A7r5 cells. Mol Nutr Food Res. 2014 May;58(5):1069-78. PMID: 24415531.

 

Hu Y, Chen L, Yi C, et al. Experimental study on inhibitory effects of diallyl sulfide on growth and invasion of human osteosarcoma MG-63 cells. J Huazhong Univ Sci Technolog Med Sci. 2012 Aug;32(4):581-5. PMID: 22886974.

 

Kang JS, Kim TM, Shim TJ, et al. Modifying effect of diallyl sulfide on colon carcinogenesis in C57BL/6J-ApcMin/+ mice. Asian Pac J Cancer Prev. 2012;13(4):1115-8. PMID: 22799291.

 

Lin X, Yu S, Chen Y, et al. Neuroprotective effects of diallyl sulfide against transient focal cerebral ischemia via anti-apoptosis in rats. Neurol Res. 2012 Jan;34(1):32-7. PMID: 22196859.

 

Ho CY, Cheng YT, Chau CF, et al. Effect of diallyl sulfide on in vitro and in vivo Nrf2-mediated pulmonic antioxidant enzyme expression via activation ERK/p38 signaling pathway. J Agric Food Chem. 2012 Jan 11;60(1):100-7. PMID: 22118872.

" Xi "UN number: 1993     Class:  3     Packing group:  III

Proper shipping name:  Flammable liquids, n.o.s. (Diallyl sulphide)

Reportable quantity (RQ):  Poison inhalation hazard:  No."

LKT D3201 Diallyl Sulfide 100 ml 276.5 Organosulfur found in garlic. Di-2-propenyl sulfide 2-Propenyl sulphide; 3,3-Thiobis(1-propene); Diallyl monosulfide; Diallyl thioether;  Allyl monosulfide; Allyl sulfide 592-88-1 ≥97% 114.21 C6H10S C=CCSCC=C Ambient Ambient Insoluble in water. "McCaskill ML, Rogan E, D Thomas R. Diallyl sulfide inhibits diethylstilbestrol induced DNA damage in human breast epithelial cells (MCF-10A). Steroids. 2014 Sep 30. [Epub ahead of print]. PMID: 25278253.

 

Ho CY, Weng CJ, Jhang JJ, et al. Diallyl sulfide as a potential dietary agent to reduce TNF-α- and histamine-induced proinflammatory responses in A7r5 cells. Mol Nutr Food Res. 2014 May;58(5):1069-78. PMID: 24415531.

 

Hu Y, Chen L, Yi C, et al. Experimental study on inhibitory effects of diallyl sulfide on growth and invasion of human osteosarcoma MG-63 cells. J Huazhong Univ Sci Technolog Med Sci. 2012 Aug;32(4):581-5. PMID: 22886974.

 

Kang JS, Kim TM, Shim TJ, et al. Modifying effect of diallyl sulfide on colon carcinogenesis in C57BL/6J-ApcMin/+ mice. Asian Pac J Cancer Prev. 2012;13(4):1115-8. PMID: 22799291.

 

Lin X, Yu S, Chen Y, et al. Neuroprotective effects of diallyl sulfide against transient focal cerebral ischemia via anti-apoptosis in rats. Neurol Res. 2012 Jan;34(1):32-7. PMID: 22196859.

 

Ho CY, Cheng YT, Chau CF, et al. Effect of diallyl sulfide on in vitro and in vivo Nrf2-mediated pulmonic antioxidant enzyme expression via activation ERK/p38 signaling pathway. J Agric Food Chem. 2012 Jan 11;60(1):100-7. PMID: 22118872.

" Xi "UN number: 1993     Class:  3     Packing group:  III

Proper shipping name:  Flammable liquids, n.o.s. (Diallyl sulphide)

Reportable quantity (RQ):  Poison inhalation hazard:  No."

LKT D3202 Diallyl Trisulfide 100 mg 101.5 Organosulfur found in garlic. Di-2-propenyl trisulfide Allyl trisulfide; DATS 2050-87-5 ≥98% 178.34 C6H10S3 C=CCSSSCC=C Ambient -20°C Soluble in acetone. Slightly soluble in ethanol (3mg/mL), DMSO (5mg/mL), 2-propanol, and DMF (10 mg/mL). "Suda S, Watanabe K, Tanaka Y, et al. Identification of molecular target of diallyl trisulfide in leukemic cells. Biosci Biotechnol Biochem. 2014;78(8):1415-7. PMID: 25130746.

 

Sumedha N, Miltonprabu S. Diallyl trisulfide ameliorates arsenic-induced hepatotoxicity by abrogation of oxidative stress, inflammation, and apoptosis in rats. Hum Exp Toxicol. 2014 Jul 25. [Epub ahead of print]. PMID: 25062976.

 

Hung FM, Shang HS, Tang NY, et al. Effects of diallyl trisulfide on induction of apoptotic death in murine leukemia WEHI-3 cells in vitro and alterations of the immune responses in normal and leukemic mice in vivo. Environ Toxicol. 2014 May 28. [Epub ahead of print]. PMID: 24890016.

 

Zhu X, Zhang F, Zhou L, et al. Diallyl trisulfide attenuates carbon tetrachloride-caused liver injury and fibrogenesis and reduces hepatic oxidative stress in rats. Naunyn Schmiedebergs Arch Pharmacol. 2014 May;387(5):445-55. PMID: 24557053.

 

Hahm ER, Singh SV. Diallyl trisulfide inhibits estrogen receptor-α activity in human breast cancer cells. Breast Cancer Res Treat. 2014 Feb;144(1):47-57. PMID: 24487688.

 

Shin DY, Cha HJ, Kim GY, et al. Inhibiting invasion into human bladder carcinoma 5637 cells with diallyl trisulfide by inhibiting matrix metalloproteinase activities and tightening tight junctions. Int J Mol Sci. 2013 Oct 1;14(10):19911-22. PMID: 24084732.

 

Wallace GC 4th, Haar CP, Vandergrift WA 3rd, et al. Multi-targeted DATS prevents tumor progression and promotes apoptosis in ectopic glioblastoma xenografts in SCID mice via HDAC inhibition. J Neurooncol. 2013 Aug;114(1):43-50. PMID: 23754639.

 

Lee HJ, Lee HG, Choi KS, et al. Diallyl trisulfide suppresses dextran sodium sulfate-induced mouse colitis: NF-κB and STAT3 as potential targets. Biochem Biophys Res Commun. 2013 Jul 26;437(2):267-73. PMID: 23811270.

 

Li Y, Zhang J, Zhang L, et al. Diallyl trisulfide inhibits proliferation, invasion and angiogenesis of osteosarcoma cells by switching on suppressor microRNAs and inactivating of Notch-1 signaling. Carcinogenesis. 2013 Jul;34(7):1601-10. PMID: 23430952.

 

Huang YT, Yao CH, Way CL, et al. Diallyl trisulfide and diallyl disulfide ameliorate cardiac dysfunction by suppressing apoptotic and enhancing survival pathways in experimental diabetic rats. J Appl Physiol (1985). 2013 Feb;114(3):402-10. PMID: 23139364.

" "UN number: 2810     Class:  6.1     Packing group:  III

Proper shipping name:  Toxic, liquids, organic, n.o.s.  (Diallyl trisulfide)

Reportable Quantity (RQ)     Marine pollutant:  No     Poison Inhalation Hazard:  No"

LKT D3202 Diallyl Trisulfide 500 mg 315.5 Organosulfur found in garlic. Di-2-propenyl trisulfide Allyl trisulfide; DATS 2050-87-5 ≥98% 178.34 C6H10S3 C=CCSSSCC=C Ambient -20°C Soluble in acetone. Slightly soluble in ethanol (3mg/mL), DMSO (5mg/mL), 2-propanol, and DMF (10 mg/mL). "Suda S, Watanabe K, Tanaka Y, et al. Identification of molecular target of diallyl trisulfide in leukemic cells. Biosci Biotechnol Biochem. 2014;78(8):1415-7. PMID: 25130746.

 

Sumedha N, Miltonprabu S. Diallyl trisulfide ameliorates arsenic-induced hepatotoxicity by abrogation of oxidative stress, inflammation, and apoptosis in rats. Hum Exp Toxicol. 2014 Jul 25. [Epub ahead of print]. PMID: 25062976.

 

Hung FM, Shang HS, Tang NY, et al. Effects of diallyl trisulfide on induction of apoptotic death in murine leukemia WEHI-3 cells in vitro and alterations of the immune responses in normal and leukemic mice in vivo. Environ Toxicol. 2014 May 28. [Epub ahead of print]. PMID: 24890016.

 

Zhu X, Zhang F, Zhou L, et al. Diallyl trisulfide attenuates carbon tetrachloride-caused liver injury and fibrogenesis and reduces hepatic oxidative stress in rats. Naunyn Schmiedebergs Arch Pharmacol. 2014 May;387(5):445-55. PMID: 24557053.

 

Hahm ER, Singh SV. Diallyl trisulfide inhibits estrogen receptor-α activity in human breast cancer cells. Breast Cancer Res Treat. 2014 Feb;144(1):47-57. PMID: 24487688.

 

Shin DY, Cha HJ, Kim GY, et al. Inhibiting invasion into human bladder carcinoma 5637 cells with diallyl trisulfide by inhibiting matrix metalloproteinase activities and tightening tight junctions. Int J Mol Sci. 2013 Oct 1;14(10):19911-22. PMID: 24084732.

 

Wallace GC 4th, Haar CP, Vandergrift WA 3rd, et al. Multi-targeted DATS prevents tumor progression and promotes apoptosis in ectopic glioblastoma xenografts in SCID mice via HDAC inhibition. J Neurooncol. 2013 Aug;114(1):43-50. PMID: 23754639.

 

Lee HJ, Lee HG, Choi KS, et al. Diallyl trisulfide suppresses dextran sodium sulfate-induced mouse colitis: NF-κB and STAT3 as potential targets. Biochem Biophys Res Commun. 2013 Jul 26;437(2):267-73. PMID: 23811270.

 

Li Y, Zhang J, Zhang L, et al. Diallyl trisulfide inhibits proliferation, invasion and angiogenesis of osteosarcoma cells by switching on suppressor microRNAs and inactivating of Notch-1 signaling. Carcinogenesis. 2013 Jul;34(7):1601-10. PMID: 23430952.

 

Huang YT, Yao CH, Way CL, et al. Diallyl trisulfide and diallyl disulfide ameliorate cardiac dysfunction by suppressing apoptotic and enhancing survival pathways in experimental diabetic rats. J Appl Physiol (1985). 2013 Feb;114(3):402-10. PMID: 23139364.

" "UN number: 2810     Class:  6.1     Packing group:  III

Proper shipping name:  Toxic, liquids, organic, n.o.s.  (Diallyl trisulfide)

Reportable Quantity (RQ)     Marine pollutant:  No     Poison Inhalation Hazard:  No"

LKT D3202 Diallyl Trisulfide 1 g 532.1 Organosulfur found in garlic. Di-2-propenyl trisulfide Allyl trisulfide; DATS 2050-87-5 ≥98% 178.34 C6H10S3 C=CCSSSCC=C Ambient -20°C Soluble in acetone. Slightly soluble in ethanol (3mg/mL), DMSO (5mg/mL), 2-propanol, and DMF (10 mg/mL). "Suda S, Watanabe K, Tanaka Y, et al. Identification of molecular target of diallyl trisulfide in leukemic cells. Biosci Biotechnol Biochem. 2014;78(8):1415-7. PMID: 25130746.

 

Sumedha N, Miltonprabu S. Diallyl trisulfide ameliorates arsenic-induced hepatotoxicity by abrogation of oxidative stress, inflammation, and apoptosis in rats. Hum Exp Toxicol. 2014 Jul 25. [Epub ahead of print]. PMID: 25062976.

 

Hung FM, Shang HS, Tang NY, et al. Effects of diallyl trisulfide on induction of apoptotic death in murine leukemia WEHI-3 cells in vitro and alterations of the immune responses in normal and leukemic mice in vivo. Environ Toxicol. 2014 May 28. [Epub ahead of print]. PMID: 24890016.

 

Zhu X, Zhang F, Zhou L, et al. Diallyl trisulfide attenuates carbon tetrachloride-caused liver injury and fibrogenesis and reduces hepatic oxidative stress in rats. Naunyn Schmiedebergs Arch Pharmacol. 2014 May;387(5):445-55. PMID: 24557053.

 

Hahm ER, Singh SV. Diallyl trisulfide inhibits estrogen receptor-α activity in human breast cancer cells. Breast Cancer Res Treat. 2014 Feb;144(1):47-57. PMID: 24487688.

 

Shin DY, Cha HJ, Kim GY, et al. Inhibiting invasion into human bladder carcinoma 5637 cells with diallyl trisulfide by inhibiting matrix metalloproteinase activities and tightening tight junctions. Int J Mol Sci. 2013 Oct 1;14(10):19911-22. PMID: 24084732.

 

Wallace GC 4th, Haar CP, Vandergrift WA 3rd, et al. Multi-targeted DATS prevents tumor progression and promotes apoptosis in ectopic glioblastoma xenografts in SCID mice via HDAC inhibition. J Neurooncol. 2013 Aug;114(1):43-50. PMID: 23754639.

 

Lee HJ, Lee HG, Choi KS, et al. Diallyl trisulfide suppresses dextran sodium sulfate-induced mouse colitis: NF-κB and STAT3 as potential targets. Biochem Biophys Res Commun. 2013 Jul 26;437(2):267-73. PMID: 23811270.

 

Li Y, Zhang J, Zhang L, et al. Diallyl trisulfide inhibits proliferation, invasion and angiogenesis of osteosarcoma cells by switching on suppressor microRNAs and inactivating of Notch-1 signaling. Carcinogenesis. 2013 Jul;34(7):1601-10. PMID: 23430952.

 

Huang YT, Yao CH, Way CL, et al. Diallyl trisulfide and diallyl disulfide ameliorate cardiac dysfunction by suppressing apoptotic and enhancing survival pathways in experimental diabetic rats. J Appl Physiol (1985). 2013 Feb;114(3):402-10. PMID: 23139364.

" "UN number: 2810     Class:  6.1     Packing group:  III

Proper shipping name:  Toxic, liquids, organic, n.o.s.  (Diallyl trisulfide)

Reportable Quantity (RQ)     Marine pollutant:  No     Poison Inhalation Hazard:  No"

LKT D3575 2,5-Di-tert-butyl-4-hydroxyanisole 1 g 160.8 BHA derivative; potential Ca2+ ATPase inhibitor. 2,5-di-tert-butyl-4-methoxyphenol 1991-52-2 ≥98% 236.35 C15H24O2 CC(C)(C)C1=CC(=C(C=C1OC)C(C)(C)C)O Ambient 4°C "Qu J, Adam J, Bloxham DM, et al. Phosphatidylserine-dependent adhesion of T cells to endothelial cells. Biochim Biophys Acta. 2000 Jun 15;1501(2-3):99-115. PMID: 10838184.

 

Lam LK, Garg P. Tumorigenicity of di-tert-butyl-substituted hydroquinone and hydroxyanisoles in the forestomach of Syrian golden hamsters. Carcinogenesis. 1991 Jul;12(7):1341-4. PMID: 2070501.

 

Mizutani T. Protective effects of butylated hydroxyanisole and its analogs on the lung toxicity of butylated hydroxytoluene in mice. Res Commun Chem Pathol Pharmacol. 1985 Oct;50(1):125-33. PMID: 4081305.

" Xi Not dangerous goods.

LKT D3575 2,5-Di-tert-butyl-4-hydroxyanisole 5 g 542 BHA derivative; potential Ca2+ ATPase inhibitor. 2,5-di-tert-butyl-4-methoxyphenol 1991-52-2 ≥98% 236.35 C15H24O2 CC(C)(C)C1=CC(=C(C=C1OC)C(C)(C)C)O Ambient 4°C "Qu J, Adam J, Bloxham DM, et al. Phosphatidylserine-dependent adhesion of T cells to endothelial cells. Biochim Biophys Acta. 2000 Jun 15;1501(2-3):99-115. PMID: 10838184.

 

Lam LK, Garg P. Tumorigenicity of di-tert-butyl-substituted hydroquinone and hydroxyanisoles in the forestomach of Syrian golden hamsters. Carcinogenesis. 1991 Jul;12(7):1341-4. PMID: 2070501.

 

Mizutani T. Protective effects of butylated hydroxyanisole and its analogs on the lung toxicity of butylated hydroxytoluene in mice. Res Commun Chem Pathol Pharmacol. 1985 Oct;50(1):125-33. PMID: 4081305.

" Xi Not dangerous goods.

LKT D3209 Diclofenac Sodium 10 g 45.3 NSAID; COX-1/2 inhibitor, potential K+ channel modulator. 2-[(2,6-Dichlorophenyl)amino]benzeneacetic acid Voltarol 15307-79-6 ≥98% 318.14 C14H10Cl2NNaO2 C1=CC=C(C(=C1)CC(=O)[O-])NC2=C(C=CC=C2Cl)Cl.[Na+] Ambient Ambient Soluble in water or acetone. "Arumugam A, Weng Z, Talwelkar SS, et al. Inhibiting cycloxygenase and ornithine decarboxylase by diclofenac and alpha-difluoromethylornithine blocks cutaneous SCCs by targeting Akt-ERK axis. PLoS One. 2013 Nov 8;8(11):e80076. PMID: 24260338.

 

Akbari E, Mirzaei E, Shahabi Majd N. Long-term Morphine-treated Rats are more Sensitive to Antinociceptive Effect of Diclofenac than the Morphine-naive rats. Iran J Pharm Res. 2013 Winter;12(1):175-84. PMID: 24250586.

 

Huang CW, Hung TY, Liao YK, et al. Underlying mechanism of regulatory actions of diclofenac, a nonsteroidal anti-inflammatory agent, on neuronal potassium channels and firing: an experimental and theoretical study. J Physiol Pharmacol. 2013 Jun;64(3):269-80. PMID: 23959723.

 

Kaur J, Sanyal SN. Diclofenac, a selective COX-2 inhibitor, inhibits DMH-induced colon tumorigenesis through suppression of MCP-1, MIP-1α and VEGF. Mol Carcinog. 2011 Sep;50(9):707-18. PMID: 21268133.

" T "UN number: 2811     Class:  6.1     Packing group:  III

Proper shipping name:  Toxic solids, organic, n.o.s. (Sodium [2-[(2,6-dichlorophenyl)amino]phenyl]acetate)

Reportable Quantity (RQ):     Marine pollutant:  No     Poison inhalation hazard:  No"

LKT D3209 Diclofenac Sodium 25 g 64.7 NSAID; COX-1/2 inhibitor, potential K+ channel modulator. 2-[(2,6-Dichlorophenyl)amino]benzeneacetic acid Voltarol 15307-79-6 ≥98% 318.14 C14H10Cl2NNaO2 C1=CC=C(C(=C1)CC(=O)[O-])NC2=C(C=CC=C2Cl)Cl.[Na+] Ambient Ambient Soluble in water or acetone. "Arumugam A, Weng Z, Talwelkar SS, et al. Inhibiting cycloxygenase and ornithine decarboxylase by diclofenac and alpha-difluoromethylornithine blocks cutaneous SCCs by targeting Akt-ERK axis. PLoS One. 2013 Nov 8;8(11):e80076. PMID: 24260338.

 

Akbari E, Mirzaei E, Shahabi Majd N. Long-term Morphine-treated Rats are more Sensitive to Antinociceptive Effect of Diclofenac than the Morphine-naive rats. Iran J Pharm Res. 2013 Winter;12(1):175-84. PMID: 24250586.

 

Huang CW, Hung TY, Liao YK, et al. Underlying mechanism of regulatory actions of diclofenac, a nonsteroidal anti-inflammatory agent, on neuronal potassium channels and firing: an experimental and theoretical study. J Physiol Pharmacol. 2013 Jun;64(3):269-80. PMID: 23959723.

 

Kaur J, Sanyal SN. Diclofenac, a selective COX-2 inhibitor, inhibits DMH-induced colon tumorigenesis through suppression of MCP-1, MIP-1α and VEGF. Mol Carcinog. 2011 Sep;50(9):707-18. PMID: 21268133.

" T "UN number: 2811     Class:  6.1     Packing group:  III

Proper shipping name:  Toxic solids, organic, n.o.s. (Sodium [2-[(2,6-dichlorophenyl)amino]phenyl]acetate)

Reportable Quantity (RQ):     Marine pollutant:  No     Poison inhalation hazard:  No"

LKT D3209 Diclofenac Sodium 100 g 161.8 NSAID; COX-1/2 inhibitor, potential K+ channel modulator. 2-[(2,6-Dichlorophenyl)amino]benzeneacetic acid Voltarol 15307-79-6 ≥98% 318.14 C14H10Cl2NNaO2 C1=CC=C(C(=C1)CC(=O)[O-])NC2=C(C=CC=C2Cl)Cl.[Na+] Ambient Ambient Soluble in water or acetone. "Arumugam A, Weng Z, Talwelkar SS, et al. Inhibiting cycloxygenase and ornithine decarboxylase by diclofenac and alpha-difluoromethylornithine blocks cutaneous SCCs by targeting Akt-ERK axis. PLoS One. 2013 Nov 8;8(11):e80076. PMID: 24260338.

 

Akbari E, Mirzaei E, Shahabi Majd N. Long-term Morphine-treated Rats are more Sensitive to Antinociceptive Effect of Diclofenac than the Morphine-naive rats. Iran J Pharm Res. 2013 Winter;12(1):175-84. PMID: 24250586.

 

Huang CW, Hung TY, Liao YK, et al. Underlying mechanism of regulatory actions of diclofenac, a nonsteroidal anti-inflammatory agent, on neuronal potassium channels and firing: an experimental and theoretical study. J Physiol Pharmacol. 2013 Jun;64(3):269-80. PMID: 23959723.

 

Kaur J, Sanyal SN. Diclofenac, a selective COX-2 inhibitor, inhibits DMH-induced colon tumorigenesis through suppression of MCP-1, MIP-1α and VEGF. Mol Carcinog. 2011 Sep;50(9):707-18. PMID: 21268133.

" T "UN number: 2811     Class:  6.1     Packing group:  III

Proper shipping name:  Toxic solids, organic, n.o.s. (Sodium [2-[(2,6-dichlorophenyl)amino]phenyl]acetate)

Reportable Quantity (RQ):     Marine pollutant:  No     Poison inhalation hazard:  No"

LKT D3221 Difluoromethylornithine Hydrochloride Monohydrate 10 mg 67.9 Ornithine decarboxylase inhibitor. 2-(Difluoromethyl)-DL-ornithine Hydrochloride Monohydrate Eflornithine HCl H2O; DFMO HCl H2O 96020-91-6 ≥98% 236.65 C6H12F2N2O2 HCl H2O C(CC(C(F)F)(C(=O)O)N)CN.Cl Ambient -20°C Soluble in water. Insoluble in acetone or chloroform. "Singh AK, Roberts S, Ullman B, et al. A quantitative proteomic screen to identify potential drug resistance mechanism in α-difluoromethylornithine (DFMO) resistant Leishmania donovani. J Proteomics. 2014 May 6;102:44-59. PMID: 24631822.

 

Tysoe C, Withers SG. Fluorinated mechanism-based inhibitors: common themes and recent developments. Curr Top Med Chem. 2014;14(7):865-74. PMID: 24484426.

 

Arumugam A, Weng Z, Talwelkar SS, et al. Inhibiting cycloxygenase and ornithine decarboxylase by diclofenac and alpha-difluoromethylornithine blocks cutaneous SCCs by targeting Akt-ERK axis. PLoS One. 2013 Nov 8;8(11):e80076. PMID: 24260338.

 

Xu H, Washington S, Verderame MF, et al. Activation of protein kinase A (PKA) signaling mitigates the antiproliferative and antiinvasive effects of alpha-difluoromethylornithine in breast cancer cells. Breast Cancer Res Treat. 2008 Jan;107(1):63-70. PMID: 17333334.

 

Lima e Silva R, Saishin Y, Saishin Y, et al. Suppression and regression of choroidal neovascularization by polyamine analogues. Invest Ophthalmol Vis Sci. 2005 Sep;46(9):3323-30. PMID: 16123436.

 

Fong LY, Nguyen VT, Pegg AE, et al. Alpha-difluoromethylornithine induction of apoptosis: a mechanism which reverses pre-established cell proliferation and cancer initiation in esophageal carcinogenesis in zinc-deficient rats. Cancer Epidemiol Biomarkers Prev. 2001 Mar;10(3):191-9. PMID: 11303587.

" Not dangerous goods.

LKT D3221 Difluoromethylornithine Hydrochloride Monohydrate 25 mg 136 Ornithine decarboxylase inhibitor. 2-(Difluoromethyl)-DL-ornithine Hydrochloride Monohydrate Eflornithine HCl H2O; DFMO HCl H2O 96020-91-6 ≥98% 236.65 C6H12F2N2O2 HCl H2O C(CC(C(F)F)(C(=O)O)N)CN.Cl Ambient -20°C Soluble in water. Insoluble in acetone or chloroform. "Singh AK, Roberts S, Ullman B, et al. A quantitative proteomic screen to identify potential drug resistance mechanism in α-difluoromethylornithine (DFMO) resistant Leishmania donovani. J Proteomics. 2014 May 6;102:44-59. PMID: 24631822.

 

Tysoe C, Withers SG. Fluorinated mechanism-based inhibitors: common themes and recent developments. Curr Top Med Chem. 2014;14(7):865-74. PMID: 24484426.

 

Arumugam A, Weng Z, Talwelkar SS, et al. Inhibiting cycloxygenase and ornithine decarboxylase by diclofenac and alpha-difluoromethylornithine blocks cutaneous SCCs by targeting Akt-ERK axis. PLoS One. 2013 Nov 8;8(11):e80076. PMID: 24260338.

 

Xu H, Washington S, Verderame MF, et al. Activation of protein kinase A (PKA) signaling mitigates the antiproliferative and antiinvasive effects of alpha-difluoromethylornithine in breast cancer cells. Breast Cancer Res Treat. 2008 Jan;107(1):63-70. PMID: 17333334.

 

Lima e Silva R, Saishin Y, Saishin Y, et al. Suppression and regression of choroidal neovascularization by polyamine analogues. Invest Ophthalmol Vis Sci. 2005 Sep;46(9):3323-30. PMID: 16123436.

 

Fong LY, Nguyen VT, Pegg AE, et al. Alpha-difluoromethylornithine induction of apoptosis: a mechanism which reverses pre-established cell proliferation and cancer initiation in esophageal carcinogenesis in zinc-deficient rats. Cancer Epidemiol Biomarkers Prev. 2001 Mar;10(3):191-9. PMID: 11303587.

" Not dangerous goods.

LKT D3228 Dihydromyristicin 100 mg 96.6 Found in parsley. 1-methoxy-5-propyl-2,3-(methylenedioxy)benzene 52811-28-6 ≥98% 194.23 C11H14O3 CCCC1=CC2=C(C(=C1)OC)OCO2 Ambient -20°C Insoluble in water; soluble in benzene and ether; slightly soluble in ethanol Zheng GQ, Kenney PM, Zhang J, et al. Inhibition of benzo[a]pyrene-induced tumorigenesis by myristicin, a volatile aroma constituent of parsley leaf oil. Carcinogenesis. 1992 Oct;13(10):1921-3. PMID: 1423855. Not dangerous goods.

LKT D3228 Dihydromyristicin 500 mg 323.2 Found in parsley. 1-methoxy-5-propyl-2,3-(methylenedioxy)benzene 52811-28-6 ≥98% 194.23 C11H14O3 CCCC1=CC2=C(C(=C1)OC)OCO2 Ambient -20°C Insoluble in water; soluble in benzene and ether; slightly soluble in ethanol Zheng GQ, Kenney PM, Zhang J, et al. Inhibition of benzo[a]pyrene-induced tumorigenesis by myristicin, a volatile aroma constituent of parsley leaf oil. Carcinogenesis. 1992 Oct;13(10):1921-3. PMID: 1423855. Not dangerous goods.

LKT D3228 Dihydromyristicin 1 g 582.3 Found in parsley. 1-methoxy-5-propyl-2,3-(methylenedioxy)benzene 52811-28-6 ≥98% 194.23 C11H14O3 CCCC1=CC2=C(C(=C1)OC)OCO2 Ambient -20°C Insoluble in water; soluble in benzene and ether; slightly soluble in ethanol Zheng GQ, Kenney PM, Zhang J, et al. Inhibition of benzo[a]pyrene-induced tumorigenesis by myristicin, a volatile aroma constituent of parsley leaf oil. Carcinogenesis. 1992 Oct;13(10):1921-3. PMID: 1423855. Not dangerous goods.

LKT D3232 3,3′-Diindolylmethane 1 g 34.3 Indole found in cruciferous vegetables; AhR agonist. 3,3'-Diindolymethane; 3,3'-Methylenebis-1H-indole; DIM 1968-05-4 ≥98% 246.31 C17H14N2 C1=CC=C2C(=C1)C(=CN2)CC3=CNC4=CC=CC=C43 Ambient Ambient Soluble in DMSO (200 mg/mL), insoluble in water. "Liu Y, She W, Wang F, et al. 3, 3'-diindolylmethane alleviates steatosis and the progression of NASH partly through shifting the imbalance of Treg/Th17 cells to Treg dominance. Int Immunopharmacol. 2014 Oct 1. [Epub ahead of print]. PMID: 25281898.

 

Rouse M, Rao R, Nagarkatti M, et al. 3,3'-diindolylmethane ameliorates experimental autoimmune encephalomyelitis by promoting cell cycle arrest and apoptosis in activated T cells through microRNA signaling pathways. J Pharmacol Exp Ther. 2014 Aug;350(2):341-52. PMID: 24898268.

 

Wu T, Chen C, Li F, et al. 3,3'-Diindolylmethane inhibits the invasion and metastasis of nasopharyngeal carcinoma cells in vitro and in vivo by regulation of epithelial mesenchymal transition. Exp Ther Med. 2014 Jun;7(6):1635-1638. PMID: 24926357.

 

Poornima J, Mirunalini S. Regulation of carbohydrate metabolism by indole-3-carbinol and its metabolite 3,3'-diindolylmethane in high-fat diet-induced C57BL/6J mice. Mol Cell Biochem. 2014 Jan;385(1-2):7-15. PMID: 24072613.

 

Zhang Z, Gao Z, Hu W, et al. 3,3'-Diindolylmethane ameliorates experimental hepatic fibrosis via inhibiting miR-21 expression. Br J Pharmacol. 2013 Oct;170(3):649-60. PMID: 23902531.

 

Chen C, Chen SM, Xu B, et al. In vivo and in vitro study on the role of 3,3'-diindolylmethane in treatment and prevention of nasopharyngeal carcinoma. Carcinogenesis. 2013 Aug;34(8):1815-21. PMID: 23568953.

 

Beaver LM, Yu TW, Sokolowski EI, et al. 3,3'-Diindolylmethane, but not indole-3-carbinol, inhibits histone deacetylase activity in prostate cancer cells. Toxicol Appl Pharmacol. 2012 Sep 15;263(3):345-51. PMID: 22800507.

 

Cho HJ, Seon MR, LLee YM, et al. 3,3’-Diindolylmethane suppresses the inflammatory response to lipopolysacharide in murine macrophages. J Nutr. 2008 Jan;138(1):17-23. PMID: 18156398.

" Not dangerous goods.

LKT D3232 3,3′-Diindolylmethane 5 g 107.4 Indole found in cruciferous vegetables; AhR agonist. 3,3'-Diindolymethane; 3,3'-Methylenebis-1H-indole; DIM 1968-05-4 ≥98% 246.31 C17H14N2 C1=CC=C2C(=C1)C(=CN2)CC3=CNC4=CC=CC=C43 Ambient Ambient Soluble in DMSO (200 mg/mL), insoluble in water. "Liu Y, She W, Wang F, et al. 3, 3'-diindolylmethane alleviates steatosis and the progression of NASH partly through shifting the imbalance of Treg/Th17 cells to Treg dominance. Int Immunopharmacol. 2014 Oct 1. [Epub ahead of print]. PMID: 25281898.

 

Rouse M, Rao R, Nagarkatti M, et al. 3,3'-diindolylmethane ameliorates experimental autoimmune encephalomyelitis by promoting cell cycle arrest and apoptosis in activated T cells through microRNA signaling pathways. J Pharmacol Exp Ther. 2014 Aug;350(2):341-52. PMID: 24898268.

 

Wu T, Chen C, Li F, et al. 3,3'-Diindolylmethane inhibits the invasion and metastasis of nasopharyngeal carcinoma cells in vitro and in vivo by regulation of epithelial mesenchymal transition. Exp Ther Med. 2014 Jun;7(6):1635-1638. PMID: 24926357.

 

Poornima J, Mirunalini S. Regulation of carbohydrate metabolism by indole-3-carbinol and its metabolite 3,3'-diindolylmethane in high-fat diet-induced C57BL/6J mice. Mol Cell Biochem. 2014 Jan;385(1-2):7-15. PMID: 24072613.

 

Zhang Z, Gao Z, Hu W, et al. 3,3'-Diindolylmethane ameliorates experimental hepatic fibrosis via inhibiting miR-21 expression. Br J Pharmacol. 2013 Oct;170(3):649-60. PMID: 23902531.

 

Chen C, Chen SM, Xu B, et al. In vivo and in vitro study on the role of 3,3'-diindolylmethane in treatment and prevention of nasopharyngeal carcinoma. Carcinogenesis. 2013 Aug;34(8):1815-21. PMID: 23568953.

 

Beaver LM, Yu TW, Sokolowski EI, et al. 3,3'-Diindolylmethane, but not indole-3-carbinol, inhibits histone deacetylase activity in prostate cancer cells. Toxicol Appl Pharmacol. 2012 Sep 15;263(3):345-51. PMID: 22800507.

 

Cho HJ, Seon MR, LLee YM, et al. 3,3’-Diindolylmethane suppresses the inflammatory response to lipopolysacharide in murine macrophages. J Nutr. 2008 Jan;138(1):17-23. PMID: 18156398.

" Not dangerous goods.

LKT D3232 3,3′-Diindolylmethane 10 g 188 Indole found in cruciferous vegetables; AhR agonist. 3,3'-Diindolymethane; 3,3'-Methylenebis-1H-indole; DIM 1968-05-4 ≥98% 246.31 C17H14N2 C1=CC=C2C(=C1)C(=CN2)CC3=CNC4=CC=CC=C43 Ambient Ambient Soluble in DMSO (200 mg/mL), insoluble in water. "Liu Y, She W, Wang F, et al. 3, 3'-diindolylmethane alleviates steatosis and the progression of NASH partly through shifting the imbalance of Treg/Th17 cells to Treg dominance. Int Immunopharmacol. 2014 Oct 1. [Epub ahead of print]. PMID: 25281898.

 

Rouse M, Rao R, Nagarkatti M, et al. 3,3'-diindolylmethane ameliorates experimental autoimmune encephalomyelitis by promoting cell cycle arrest and apoptosis in activated T cells through microRNA signaling pathways. J Pharmacol Exp Ther. 2014 Aug;350(2):341-52. PMID: 24898268.

 

Wu T, Chen C, Li F, et al. 3,3'-Diindolylmethane inhibits the invasion and metastasis of nasopharyngeal carcinoma cells in vitro and in vivo by regulation of epithelial mesenchymal transition. Exp Ther Med. 2014 Jun;7(6):1635-1638. PMID: 24926357.

 

Poornima J, Mirunalini S. Regulation of carbohydrate metabolism by indole-3-carbinol and its metabolite 3,3'-diindolylmethane in high-fat diet-induced C57BL/6J mice. Mol Cell Biochem. 2014 Jan;385(1-2):7-15. PMID: 24072613.

 

Zhang Z, Gao Z, Hu W, et al. 3,3'-Diindolylmethane ameliorates experimental hepatic fibrosis via inhibiting miR-21 expression. Br J Pharmacol. 2013 Oct;170(3):649-60. PMID: 23902531.

 

Chen C, Chen SM, Xu B, et al. In vivo and in vitro study on the role of 3,3'-diindolylmethane in treatment and prevention of nasopharyngeal carcinoma. Carcinogenesis. 2013 Aug;34(8):1815-21. PMID: 23568953.

 

Beaver LM, Yu TW, Sokolowski EI, et al. 3,3'-Diindolylmethane, but not indole-3-carbinol, inhibits histone deacetylase activity in prostate cancer cells. Toxicol Appl Pharmacol. 2012 Sep 15;263(3):345-51. PMID: 22800507.

 

Cho HJ, Seon MR, LLee YM, et al. 3,3’-Diindolylmethane suppresses the inflammatory response to lipopolysacharide in murine macrophages. J Nutr. 2008 Jan;138(1):17-23. PMID: 18156398.

" Not dangerous goods.

LKT D3261 Dipropyl Disulfide 25 g 86.2 Organosulfide found in Allium; cholesterol synthesis inhibitor. 4,5-Dithiaoctane; Di-n-propyl disulfide; n-Propyl disulfide; Propyldithiopropane; n-Propyl disulfide; Propyl disulfide  629-19-6 ≥98% 150.31 C6H14S2 CCCSSCCC Ambient Ambient Insoluble in water. "Tsai CW, Liu KL, Lin CY, et al. Structure and function relationship study of allium organosulfur compounds on upregulating the pi class of glutathione S-transferase expression. J Agric Food Chem. 2011 Apr 13;59(7):3398-405. PMID: 21381664.

 

Arranz N, Haza AI, García A, et al. Protective effects of organosulfur compounds towards N-nitrosamine-induced DNA damage in the single-cell gel electrophoresis (SCGE)/HepG2 assay. Food Chem Toxicol. 2007 Sep;45(9):1662-9. PMID: 17434656.

 

Yeh YY, Liu L. Cholesterol-lowering effect of garlic extracts and organosulfur compounds: human and animal studies. J Nutr. 2001 Mar;131(3s):989S-93S. PMID: 11238803.

 

Srivastava SK, Hu X, Xia H, et al. Mechanism of differential efficacy of garlic organosulfides in preventing benzo(a)pyrene-induced cancer in mice. Cancer Lett. 1997 Sep 16;118(1):61-7. PMID: 9310261.

" Xi "UN number: 3334     Class:  9     Packing Group: III

Proper shipping name:  Aviation regulated liquid, n.o.s. (Dipropyl disulfide)

Reportable Quantity (RQ):     Marine pollutant:  No     Poison inhalation hazard:  No"

LKT D3261 Dipropyl Disulfide 100 g 266.9 Organosulfide found in Allium; cholesterol synthesis inhibitor. 4,5-Dithiaoctane; Di-n-propyl disulfide; n-Propyl disulfide; Propyldithiopropane; n-Propyl disulfide; Propyl disulfide  629-19-6 ≥98% 150.31 C6H14S2 CCCSSCCC Ambient Ambient Insoluble in water. "Tsai CW, Liu KL, Lin CY, et al. Structure and function relationship study of allium organosulfur compounds on upregulating the pi class of glutathione S-transferase expression. J Agric Food Chem. 2011 Apr 13;59(7):3398-405. PMID: 21381664.

 

Arranz N, Haza AI, García A, et al. Protective effects of organosulfur compounds towards N-nitrosamine-induced DNA damage in the single-cell gel electrophoresis (SCGE)/HepG2 assay. Food Chem Toxicol. 2007 Sep;45(9):1662-9. PMID: 17434656.

 

Yeh YY, Liu L. Cholesterol-lowering effect of garlic extracts and organosulfur compounds: human and animal studies. J Nutr. 2001 Mar;131(3s):989S-93S. PMID: 11238803.

 

Srivastava SK, Hu X, Xia H, et al. Mechanism of differential efficacy of garlic organosulfides in preventing benzo(a)pyrene-induced cancer in mice. Cancer Lett. 1997 Sep 16;118(1):61-7. PMID: 9310261.

" Xi "UN number: 3334     Class:  9     Packing Group: III

Proper shipping name:  Aviation regulated liquid, n.o.s. (Dipropyl disulfide)

Reportable Quantity (RQ):     Marine pollutant:  No     Poison inhalation hazard:  No"

LKT D3262 Dipropyl Sulfide 10 g 64.1 Organosulfide found in Allium; cholesterol synthesis inhibitor. 4-Thiaheptane; Di-n-propyl sulfide; Dipropyl thioether; Propyl monosulfide; Propyl sulfide 111-47-7 ≥98% 118.24 C6H14S CCCSCCC Ambient Ambient Insoluble in water "Tsai CW, Liu KL, Lin CY, et al. Structure and function relationship study of allium organosulfur compounds on upregulating the pi class of glutathione S-transferase expression. J Agric Food Chem. 2011 Apr 13;59(7):3398-405. PMID: 21381664.

 

Arranz N, Haza AI, García A, et al. Protective effects of organosulfur compounds towards N-nitrosamine-induced DNA damage in the single-cell gel electrophoresis (SCGE)/HepG2 assay. Food Chem Toxicol. 2007 Sep;45(9):1662-9. PMID: 17434656.

 

Yeh YY, Liu L. Cholesterol-lowering effect of garlic extracts and organosulfur compounds: human and animal studies. J Nutr. 2001 Mar;131(3s):989S-93S. PMID: 11238803.

 

Srivastava SK, Hu X, Xia H, et al. Mechanism of differential efficacy of garlic organosulfides in preventing benzo(a)pyrene-induced cancer in mice. Cancer Lett. 1997 Sep 16;118(1):61-7. PMID: 9310261.

" Xi "UN number: 1993     Class:  3     Packing group:  III

Proper shipping name:  Flammable liquids, n.o.s. (Dipropyl sulfide)

Reportable Quantity (RQ):     Poison inhalation hazard:  No"

LKT D5612 2-n-Dodecylfuran 1 g 129 Furan derivative. 75308-12-2 ≥98% 212.38 C16H28O CCCCCCCCCCCCC1=CC=CO1 Ambient 4°C Insoluble in water Chen FC, Peng CF, Tsai IL, et al. Antitubercular constituents from the stem wood of Cinnamomum kotoense. J Nat Prod. 2005 Sep;68(9):1318-23. PMID: 16180806. Not dangerous goods.

LKT D5612 2-n-Dodecylfuran 5 g 441.8 Furan derivative. 75308-12-2 ≥98% 212.38 C16H28O CCCCCCCCCCCCC1=CC=CO1 Ambient 4°C Insoluble in water Chen FC, Peng CF, Tsai IL, et al. Antitubercular constituents from the stem wood of Cinnamomum kotoense. J Nat Prod. 2005 Sep;68(9):1318-23. PMID: 16180806. Not dangerous goods.

LKT D5612 2-n-Dodecylfuran 10 g 803.1 Furan derivative. 75308-12-2 ≥98% 212.38 C16H28O CCCCCCCCCCCCC1=CC=CO1 Ambient 4°C Insoluble in water Chen FC, Peng CF, Tsai IL, et al. Antitubercular constituents from the stem wood of Cinnamomum kotoense. J Nat Prod. 2005 Sep;68(9):1318-23. PMID: 16180806. Not dangerous goods.

LKT D5794 Doxorubicin Hydrochloride 5 mg 79.1 Anthracycline, DNA intercalator; topoisomerase II inhibitor. (8S-cis)10-[(3-Amino-2,3,6-trideoxy-α-L-lyxo- hexopyranosyl)oxy-7,8,9,10-tetrahydro-6,8,11- trihydroxy-8-(hydroacetyl)-1-methoxy-5,12- naphthacenedione Adriacin; Adriblastina; Adriamycin; Caelyx 25316-40-9 ≥98% 579.99 C27H29NO11 HCl CC1C(C(CC(O1)OC2CC(CC3=C(C4=C(C(=C23)O)C(=O)C5=C(C4=O)C=CC=C5OC)O)(C(=O)CO)O)N)O.Cl Ambient 4°C Soluble in water, methanol or aq alcohols. Soluble in DMSO to 10 mg/mL.    Insoluble in acetone, or chloroform. "Pang B, Qiao X, Janssen L, et al. Drug-induced histone eviction from open chromatin contributes to the chemotherapeutic effects of doxorubicin. Nat Commun. 2013;4:1908. PMID: 23715267.

 

Tacar O, Sriamornsak P, Dass CR. Doxorubicin: an update on anticancer molecular action, toxicity and novel drug delivery systems. J Pharm Pharmacol. 2013 Feb;65(2):157-70. PMID: 23278683.

 

Gamo FJ, Sanz LM, Vidal J, et al. Thousands of chemical starting points for antimalarial lead identification. Nature. 2010 May 20;465(7296):305-10. PMID: 20485427.

 

Squillace RM, Miller D, Cookson M, et al. Antitumor activity of ridaforolimus and potential cell-cycle determinants of sensitivity in sarcoma and endometrial cancer models. Mol Cancer Ther. 2011 Oct;10(10):1959-1968. PMID: 21825008.

" Xn, Carc. Not dangerous goods.

LKT D5794 Doxorubicin Hydrochloride 10 mg 152.7 Anthracycline, DNA intercalator; topoisomerase II inhibitor. (8S-cis)10-[(3-Amino-2,3,6-trideoxy-α-L-lyxo- hexopyranosyl)oxy-7,8,9,10-tetrahydro-6,8,11- trihydroxy-8-(hydroacetyl)-1-methoxy-5,12- naphthacenedione Adriacin; Adriblastina; Adriamycin; Caelyx 25316-40-9 ≥98% 579.99 C27H29NO11 HCl CC1C(C(CC(O1)OC2CC(CC3=C(C4=C(C(=C23)O)C(=O)C5=C(C4=O)C=CC=C5OC)O)(C(=O)CO)O)N)O.Cl Ambient 4°C Soluble in water, methanol or aq alcohols. Soluble in DMSO to 10 mg/mL.    Insoluble in acetone, or chloroform. "Pang B, Qiao X, Janssen L, et al. Drug-induced histone eviction from open chromatin contributes to the chemotherapeutic effects of doxorubicin. Nat Commun. 2013;4:1908. PMID: 23715267.

 

Tacar O, Sriamornsak P, Dass CR. Doxorubicin: an update on anticancer molecular action, toxicity and novel drug delivery systems. J Pharm Pharmacol. 2013 Feb;65(2):157-70. PMID: 23278683.

 

Gamo FJ, Sanz LM, Vidal J, et al. Thousands of chemical starting points for antimalarial lead identification. Nature. 2010 May 20;465(7296):305-10. PMID: 20485427.

 

Squillace RM, Miller D, Cookson M, et al. Antitumor activity of ridaforolimus and potential cell-cycle determinants of sensitivity in sarcoma and endometrial cancer models. Mol Cancer Ther. 2011 Oct;10(10):1959-1968. PMID: 21825008.

" Xn, Carc. Not dangerous goods.

LKT D5794 Doxorubicin Hydrochloride 50 mg 564.3 Anthracycline, DNA intercalator; topoisomerase II inhibitor. (8S-cis)10-[(3-Amino-2,3,6-trideoxy-α-L-lyxo- hexopyranosyl)oxy-7,8,9,10-tetrahydro-6,8,11- trihydroxy-8-(hydroacetyl)-1-methoxy-5,12- naphthacenedione Adriacin; Adriblastina; Adriamycin; Caelyx 25316-40-9 ≥98% 579.99 C27H29NO11 HCl CC1C(C(CC(O1)OC2CC(CC3=C(C4=C(C(=C23)O)C(=O)C5=C(C4=O)C=CC=C5OC)O)(C(=O)CO)O)N)O.Cl Ambient 4°C Soluble in water, methanol or aq alcohols. Soluble in DMSO to 10 mg/mL.    Insoluble in acetone, or chloroform. "Pang B, Qiao X, Janssen L, et al. Drug-induced histone eviction from open chromatin contributes to the chemotherapeutic effects of doxorubicin. Nat Commun. 2013;4:1908. PMID: 23715267.

 

Tacar O, Sriamornsak P, Dass CR. Doxorubicin: an update on anticancer molecular action, toxicity and novel drug delivery systems. J Pharm Pharmacol. 2013 Feb;65(2):157-70. PMID: 23278683.

 

Gamo FJ, Sanz LM, Vidal J, et al. Thousands of chemical starting points for antimalarial lead identification. Nature. 2010 May 20;465(7296):305-10. PMID: 20485427.

 

Squillace RM, Miller D, Cookson M, et al. Antitumor activity of ridaforolimus and potential cell-cycle determinants of sensitivity in sarcoma and endometrial cancer models. Mol Cancer Ther. 2011 Oct;10(10):1959-1968. PMID: 21825008.

" Xn, Carc. Not dangerous goods.

LKT E4444 Ellagic Acid 10 g 164.1 Phenol found in various fruits; HDAC modulator. 2,3,7,8-Tetrahydroxy-[1]benzopyrano[5,4,3-cde][1]benzopyran-5,10-dione Benzoaric acid; Lagistase. 476-66-4 ≥98% 302.2 C14H6O8 C1=C2C3=C(C(=C1O)O)OC(=O)C4=CC(=C(C(=C43)OC2=O)O)O Ambient Ambient Very slightly soluble in water. Soluble in 1 N NaOH (10mg/mL). "Zhou E, Fu Y, Wei Z, et al. Inhibition of allergic airway inflammation through the blockage of NF-κB activation by ellagic acid in an ovalbumin-induced mouse asthma model. Food Funct. 2014 Sep;5(9):2106-12. PMID: 24998475.

 

Kang I, Okla M, Chung S. Ellagic acid inhibits adipocyte differentiation through coactivator-associated arginine methyltransferase 1-mediated chromatin modification. J Nutr Biochem. 2014 Sep;25(9):946-53. PMID: 24929439.

 

Kowshik J, Giri H, Kiran Kishore TK, et al. Ellagic Acid Inhibits VEGF/VEGFR2, PI3K/Akt and MAPK Signaling Cascades in the Hamster Cheek Pouch Carcinogenesis Model. Anticancer Agents Med Chem. 2014 Jul 23. [Epub ahead of print]. PMID: 25060902.

 

Park SW, Kwon MJ, Yoo JY, et al. Antiviral activity and possible mode of action of ellagic acid identified in Lagerstroemia speciosa leaves toward human rhinoviruses. BMC Complement Altern Med. 2014 May 26;14:171. PMID: 24885569.

 

El-Shitany NA, El-Bastawissy EA, El-desoky K. Ellagic acid protects against carrageenan-induced acute inflammation through inhibition of nuclear factor kappa B, inducible cyclooxygenase and proinflammatory cytokines and enhancement of interleukin-10 via an antioxidant mechanism. Int Immunopharmacol. 2014 Apr;19(2):290-9. PMID: 24534771.

 

Njomnang Soh P, Witkowski B, Gales A, et al. Implication of glutathione in the in vitro antiplasmodial mechanism of action of ellagic acid. PLoS One. 2012;7(9):e45906. PMID: 23029306.

 

Beserra AM, Calegari PI, Souza Mdo C, et al. Gastroprotective and ulcer-healing mechanisms of ellagic acid in experimental rats. J Agric Food Chem. 2011 Jul 13;59(13):6957-65. PMID: 21644797

 

Feng Y, Yang SG, Du XT, et al. Ellagic acid promotes Abeta42 fibrillization and inhibits Abeta42-induced neurotoxicity. Biochem Biophys Res Commun. 2009 Dec 25;390(4):1250-4. PMID: 19878655.

 

Edderkaoui M, Odinokova I, Ohno I, et al. Ellagic acid induces apoptosis through inhibition of nuclear factor kappa B in pancreatic cancer cells. World J Gastroenterol. 2008 Jun 21;14(23):3672-80. PMID: 18595134.

 

Zhao M, Tang SN, Marsh JL, et al. Ellagic acid inhibits human pancreatic cancer growth in Balb c nude mice. Cancer Lett. 2013 Sep 1;337(2):210-217. PMID: 23684930.

" Xi Not dangerous goods.

LKT E4444 Ellagic Acid 50 g 556.5 Phenol found in various fruits; HDAC modulator. 2,3,7,8-Tetrahydroxy-[1]benzopyrano[5,4,3-cde][1]benzopyran-5,10-dione Benzoaric acid; Lagistase. 476-66-4 ≥98% 302.2 C14H6O8 C1=C2C3=C(C(=C1O)O)OC(=O)C4=CC(=C(C(=C43)OC2=O)O)O Ambient Ambient Very slightly soluble in water. Soluble in 1 N NaOH (10mg/mL). "Zhou E, Fu Y, Wei Z, et al. Inhibition of allergic airway inflammation through the blockage of NF-κB activation by ellagic acid in an ovalbumin-induced mouse asthma model. Food Funct. 2014 Sep;5(9):2106-12. PMID: 24998475.

 

Kang I, Okla M, Chung S. Ellagic acid inhibits adipocyte differentiation through coactivator-associated arginine methyltransferase 1-mediated chromatin modification. J Nutr Biochem. 2014 Sep;25(9):946-53. PMID: 24929439.

 

Kowshik J, Giri H, Kiran Kishore TK, et al. Ellagic Acid Inhibits VEGF/VEGFR2, PI3K/Akt and MAPK Signaling Cascades in the Hamster Cheek Pouch Carcinogenesis Model. Anticancer Agents Med Chem. 2014 Jul 23. [Epub ahead of print]. PMID: 25060902.

 

Park SW, Kwon MJ, Yoo JY, et al. Antiviral activity and possible mode of action of ellagic acid identified in Lagerstroemia speciosa leaves toward human rhinoviruses. BMC Complement Altern Med. 2014 May 26;14:171. PMID: 24885569.

 

El-Shitany NA, El-Bastawissy EA, El-desoky K. Ellagic acid protects against carrageenan-induced acute inflammation through inhibition of nuclear factor kappa B, inducible cyclooxygenase and proinflammatory cytokines and enhancement of interleukin-10 via an antioxidant mechanism. Int Immunopharmacol. 2014 Apr;19(2):290-9. PMID: 24534771.

 

Njomnang Soh P, Witkowski B, Gales A, et al. Implication of glutathione in the in vitro antiplasmodial mechanism of action of ellagic acid. PLoS One. 2012;7(9):e45906. PMID: 23029306.

 

Beserra AM, Calegari PI, Souza Mdo C, et al. Gastroprotective and ulcer-healing mechanisms of ellagic acid in experimental rats. J Agric Food Chem. 2011 Jul 13;59(13):6957-65. PMID: 21644797

 

Feng Y, Yang SG, Du XT, et al. Ellagic acid promotes Abeta42 fibrillization and inhibits Abeta42-induced neurotoxicity. Biochem Biophys Res Commun. 2009 Dec 25;390(4):1250-4. PMID: 19878655.

 

Edderkaoui M, Odinokova I, Ohno I, et al. Ellagic acid induces apoptosis through inhibition of nuclear factor kappa B in pancreatic cancer cells. World J Gastroenterol. 2008 Jun 21;14(23):3672-80. PMID: 18595134.

 

Zhao M, Tang SN, Marsh JL, et al. Ellagic acid inhibits human pancreatic cancer growth in Balb c nude mice. Cancer Lett. 2013 Sep 1;337(2):210-217. PMID: 23684930.

" Xi Not dangerous goods.

LKT E6880 Erucin 25 mg 122.3 ITC found in cruciferous vegetables, analog of sulforaphane; telomerase inhibitor. 1-isothiocyanato-4-(methylthio)-butane 4-methylthiobutyl isothiocyanate 4430-36-8 ≥98% 161.29 C6H11NS2 CSCCCCN=C=S Stable at room temperature. Ambient -20°C Soluble in DMSO to 75 mM, and ethanol to 75 mM. "Herz C, Hertrampf A, Zimmermann S, et al. The isothiocyanate erucin abrogates telomerase in hepatocellular carcinoma cells in vitro and in an orthotopic xenograft tumour model of HCC. J Cell Mol Med. 2014 Sep 25. [Epub ahead of print]. PMID: 25256442.

 

Cho HJ, Lee KW, Park JH. Erucin exerts anti-inflammatory properties in murine macrophages and mouse skin: possible mediation through the inhibition of NFκB signaling. Int J Mol Sci. 2013 Oct 15;14(10):20564-77. dPMID: 24132147.

 

Tarozzi A, Morroni F, Bolondi C, et al. Neuroprotective Effects of Erucin against 6-Hydroxydopamine-Induced Oxidative Damage in a Dopaminergic-like Neuroblastoma Cell Line. Int J Mol Sci. 2012;13(9):10899-910. PMID: 23109827.

 

Abbaoui B, Riedl KM, Ralston RA, et al. Inhibition of bladder cancer by broccoli isothiocyanates sulforaphane and erucin: characterization, metabolism, and interconversion. Mol Nutr Food Res. 2012 Nov;56(11):1675-87. PMID: 23038615.

 

Melchini A, Traka MH. Biological profile of erucin: a new promising anticancer agent from cruciferous vegetables. Toxins (Basel). 2010 Apr;2(4):593-612. PMID: 22069601.

 

Melchini A, Costa C, Traka M, et al. Erucin, a new promising cancer chemopreventive agent from rocket salads, shows anti-proliferative activity on human lung carcinoma A549 cells. 2009 Jul;47(7):1430-1436. PMID: 19328833.

" Not dangerous goods.

LKT E6880 Erucin 50 mg 212.1 ITC found in cruciferous vegetables, analog of sulforaphane; telomerase inhibitor. 1-isothiocyanato-4-(methylthio)-butane 4-methylthiobutyl isothiocyanate 4430-36-8 ≥98% 161.29 C6H11NS2 CSCCCCN=C=S Stable at room temperature. Ambient -20°C Soluble in DMSO to 75 mM, and ethanol to 75 mM. "Herz C, Hertrampf A, Zimmermann S, et al. The isothiocyanate erucin abrogates telomerase in hepatocellular carcinoma cells in vitro and in an orthotopic xenograft tumour model of HCC. J Cell Mol Med. 2014 Sep 25. [Epub ahead of print]. PMID: 25256442.

 

Cho HJ, Lee KW, Park JH. Erucin exerts anti-inflammatory properties in murine macrophages and mouse skin: possible mediation through the inhibition of NFκB signaling. Int J Mol Sci. 2013 Oct 15;14(10):20564-77. dPMID: 24132147.

 

Tarozzi A, Morroni F, Bolondi C, et al. Neuroprotective Effects of Erucin against 6-Hydroxydopamine-Induced Oxidative Damage in a Dopaminergic-like Neuroblastoma Cell Line. Int J Mol Sci. 2012;13(9):10899-910. PMID: 23109827.

 

Abbaoui B, Riedl KM, Ralston RA, et al. Inhibition of bladder cancer by broccoli isothiocyanates sulforaphane and erucin: characterization, metabolism, and interconversion. Mol Nutr Food Res. 2012 Nov;56(11):1675-87. PMID: 23038615.

 

Melchini A, Traka MH. Biological profile of erucin: a new promising anticancer agent from cruciferous vegetables. Toxins (Basel). 2010 Apr;2(4):593-612. PMID: 22069601.

 

Melchini A, Costa C, Traka M, et al. Erucin, a new promising cancer chemopreventive agent from rocket salads, shows anti-proliferative activity on human lung carcinoma A549 cells. 2009 Jul;47(7):1430-1436. PMID: 19328833.

" Not dangerous goods.

LKT E6880 Erucin 100 mg 362.7 ITC found in cruciferous vegetables, analog of sulforaphane; telomerase inhibitor. 1-isothiocyanato-4-(methylthio)-butane 4-methylthiobutyl isothiocyanate 4430-36-8 ≥98% 161.29 C6H11NS2 CSCCCCN=C=S Stable at room temperature. Ambient -20°C Soluble in DMSO to 75 mM, and ethanol to 75 mM. "Herz C, Hertrampf A, Zimmermann S, et al. The isothiocyanate erucin abrogates telomerase in hepatocellular carcinoma cells in vitro and in an orthotopic xenograft tumour model of HCC. J Cell Mol Med. 2014 Sep 25. [Epub ahead of print]. PMID: 25256442.

 

Cho HJ, Lee KW, Park JH. Erucin exerts anti-inflammatory properties in murine macrophages and mouse skin: possible mediation through the inhibition of NFκB signaling. Int J Mol Sci. 2013 Oct 15;14(10):20564-77. dPMID: 24132147.

 

Tarozzi A, Morroni F, Bolondi C, et al. Neuroprotective Effects of Erucin against 6-Hydroxydopamine-Induced Oxidative Damage in a Dopaminergic-like Neuroblastoma Cell Line. Int J Mol Sci. 2012;13(9):10899-910. PMID: 23109827.

 

Abbaoui B, Riedl KM, Ralston RA, et al. Inhibition of bladder cancer by broccoli isothiocyanates sulforaphane and erucin: characterization, metabolism, and interconversion. Mol Nutr Food Res. 2012 Nov;56(11):1675-87. PMID: 23038615.

 

Melchini A, Traka MH. Biological profile of erucin: a new promising anticancer agent from cruciferous vegetables. Toxins (Basel). 2010 Apr;2(4):593-612. PMID: 22069601.

 

Melchini A, Costa C, Traka M, et al. Erucin, a new promising cancer chemopreventive agent from rocket salads, shows anti-proliferative activity on human lung carcinoma A549 cells. 2009 Jul;47(7):1430-1436. PMID: 19328833.

" Not dangerous goods.

LKT E6896 Erysolin 25 mg 158.4 ITC found in cruciferous vegetables, analog of sulforaphane. 1-Isothiocyanato-4-(methylsulphonyl)butane 504-84-7 ≥97% 193.29 C6H11NO2S2 CS(=O)(=O)CCCCN=C=S Ambient -20°C "Kim MJ, Kim SH, Lim SJ. Comparison of the apoptosis-inducing capability of sulforaphane analogues in human colon cancer cells. Anticancer Res. 2010 Sep;30(9):3611-9. PMID: 20944144.

 

Zhang Y, Talalay P, Cho CG, et al. A major inducer of anticarcinogenic protective enzymes from broccoli: isolation and elucidation of structure. Proc Natl Acad Sci U S A. 1992 Mar 15;89(6):2399-403. PMID: 1549603.

" Not dangerous goods.

LKT E6896 Erysolin 50 mg 267.1 ITC found in cruciferous vegetables, analog of sulforaphane. 1-Isothiocyanato-4-(methylsulphonyl)butane 504-84-7 ≥97% 193.29 C6H11NO2S2 CS(=O)(=O)CCCCN=C=S Ambient -20°C "Kim MJ, Kim SH, Lim SJ. Comparison of the apoptosis-inducing capability of sulforaphane analogues in human colon cancer cells. Anticancer Res. 2010 Sep;30(9):3611-9. PMID: 20944144.

 

Zhang Y, Talalay P, Cho CG, et al. A major inducer of anticarcinogenic protective enzymes from broccoli: isolation and elucidation of structure. Proc Natl Acad Sci U S A. 1992 Mar 15;89(6):2399-403. PMID: 1549603.

" Not dangerous goods.

LKT E6896 Erysolin 100 mg 474.2 ITC found in cruciferous vegetables, analog of sulforaphane. 1-Isothiocyanato-4-(methylsulphonyl)butane 504-84-7 ≥97% 193.29 C6H11NO2S2 CS(=O)(=O)CCCCN=C=S Ambient -20°C "Kim MJ, Kim SH, Lim SJ. Comparison of the apoptosis-inducing capability of sulforaphane analogues in human colon cancer cells. Anticancer Res. 2010 Sep;30(9):3611-9. PMID: 20944144.

 

Zhang Y, Talalay P, Cho CG, et al. A major inducer of anticarcinogenic protective enzymes from broccoli: isolation and elucidation of structure. Proc Natl Acad Sci U S A. 1992 Mar 15;89(6):2399-403. PMID: 1549603.

" Not dangerous goods.

LKT E6896 Erysolin 500 mg 1505.2 ITC found in cruciferous vegetables, analog of sulforaphane. 1-Isothiocyanato-4-(methylsulphonyl)butane 504-84-7 ≥97% 193.29 C6H11NO2S2 CS(=O)(=O)CCCCN=C=S Ambient -20°C "Kim MJ, Kim SH, Lim SJ. Comparison of the apoptosis-inducing capability of sulforaphane analogues in human colon cancer cells. Anticancer Res. 2010 Sep;30(9):3611-9. PMID: 20944144.

 

Zhang Y, Talalay P, Cho CG, et al. A major inducer of anticarcinogenic protective enzymes from broccoli: isolation and elucidation of structure. Proc Natl Acad Sci U S A. 1992 Mar 15;89(6):2399-403. PMID: 1549603.

" Not dangerous goods.

LKT E7657 Etoposide 100 mg 86 Podophyllotoxin derivative; topoisomerase II inhibitor. 9-[(4,6-O-Ethylidene-β-D-glucopyranosyl)oxy]-5,8,- 8a,9-tetrahydro-5-(4-hydroxy-3,5-dimethoxyphenyl)- furo[3',4':6,7]naphtho[2,3-d]-1,3-dioxol-6(5aH)-one EPEG; Lastet; Vepesid 33419-42-0 ≥98% 588.56 C29H32O13 CC1OCC2C(O1)C(C(C(O2)OC3C4COC(=O)C4C(C5=CC6=C(C=C35)OCO6)C7=CC(=C(C(=C7)OC)O)OC)O)O Ambient Ambient Slightly soluble in ethanol or chloroform. Practically insoluble in water. "Johnson TS, Terrell CE, Millen SH, et al. Etoposide selectively ablates activated T cells to control the immunoregulatory disorder hemophagocytic lymphohistiocytosis. J Immunol. 2014 Jan 1;192(1):84-91. PMID: 24259502.

 

Mir Mohammadrezaei F, Mohseni kouchesfehani H, Montazeri H, et al. Signaling crosstalk of FHIT, CHK2 and p38 in etoposide induced growth inhibition in MCF-7 cells. Cell Signal. 2013 Jan;25(1):126-32. PMID: 23000346.

 

Yoo SH, Yoon YG, Lee JS, et al. Etoposide induces a mixed type of programmed cell death and overcomes the resistance conferred by Bcl-2 in Hep3B hepatoma cells. Int J Oncol. 2012 Oct;41(4):1443-54. PMID: 22895528.

 

Shin SY, Kim CG, Ko J, et al. Transcriptional and post-transcriptional regulation of the PKC delta gene by etoposide in L1210 murine leukemia cells: implication of PKC delta autoregulation. J Mol Biol. 2004 Jul 16;340(4):681-93. PMID: 15223313.

 

Mizumoto K, Rothman RJ, Farber JL. Programmed cell death (apoptosis) of mouse fibroblasts is induced by the topoisomerase II inhibitor etoposide. Mol Pharmacol. 1994 Nov;46(5):890-5. PMID: 7969076.

 

Nissen NI, Dombernowsky P, Hansen HH, et al. The epipodophyllotoxin derivatives VM-26 and VP-16-213, 1976-1979, a review. Recent Results Cancer Res. 1980;74:98-106. PMID: 7003663.

 

Marcon L, Zhang X, Hales BF, et al. Effects of chemotherapeutic agents for testicular cancer on rat spermatogonial stem/progenitor cells. J Androl. 2011 Jul-Aug;32(4):432-443. PMID: 21088230.

 

Li Z, Sun B, Clewell RA, et al. Dose-response modeling of etoposide-induced DNA damage response. Toxicol Sci. 2014 Feb;137(2):371-384. PMID: 24241721.

 

Zhang F, Koh GY, Hollingsworth J, et al. Reformulation of etoposide with solubility-enhancing rubusoside. Int J Pharm. 2012 Sep 15;434(1-2):453-459. PMID: 22698860." Xn, Carc., Xi Not dangerous goods.

LKT E7657 Etoposide 500 mg 225.1 Podophyllotoxin derivative; topoisomerase II inhibitor. 9-[(4,6-O-Ethylidene-β-D-glucopyranosyl)oxy]-5,8,- 8a,9-tetrahydro-5-(4-hydroxy-3,5-dimethoxyphenyl)- furo[3',4':6,7]naphtho[2,3-d]-1,3-dioxol-6(5aH)-one EPEG; Lastet; Vepesid 33419-42-0 ≥98% 588.56 C29H32O13 CC1OCC2C(O1)C(C(C(O2)OC3C4COC(=O)C4C(C5=CC6=C(C=C35)OCO6)C7=CC(=C(C(=C7)OC)O)OC)O)O Ambient Ambient Slightly soluble in ethanol or chloroform. Practically insoluble in water. "Johnson TS, Terrell CE, Millen SH, et al. Etoposide selectively ablates activated T cells to control the immunoregulatory disorder hemophagocytic lymphohistiocytosis. J Immunol. 2014 Jan 1;192(1):84-91. PMID: 24259502.

 

Mir Mohammadrezaei F, Mohseni kouchesfehani H, Montazeri H, et al. Signaling crosstalk of FHIT, CHK2 and p38 in etoposide induced growth inhibition in MCF-7 cells. Cell Signal. 2013 Jan;25(1):126-32. PMID: 23000346.

 

Yoo SH, Yoon YG, Lee JS, et al. Etoposide induces a mixed type of programmed cell death and overcomes the resistance conferred by Bcl-2 in Hep3B hepatoma cells. Int J Oncol. 2012 Oct;41(4):1443-54. PMID: 22895528.

 

Shin SY, Kim CG, Ko J, et al. Transcriptional and post-transcriptional regulation of the PKC delta gene by etoposide in L1210 murine leukemia cells: implication of PKC delta autoregulation. J Mol Biol. 2004 Jul 16;340(4):681-93. PMID: 15223313.

 

Mizumoto K, Rothman RJ, Farber JL. Programmed cell death (apoptosis) of mouse fibroblasts is induced by the topoisomerase II inhibitor etoposide. Mol Pharmacol. 1994 Nov;46(5):890-5. PMID: 7969076.

 

Nissen NI, Dombernowsky P, Hansen HH, et al. The epipodophyllotoxin derivatives VM-26 and VP-16-213, 1976-1979, a review. Recent Results Cancer Res. 1980;74:98-106. PMID: 7003663.

 

Marcon L, Zhang X, Hales BF, et al. Effects of chemotherapeutic agents for testicular cancer on rat spermatogonial stem/progenitor cells. J Androl. 2011 Jul-Aug;32(4):432-443. PMID: 21088230.

 

Li Z, Sun B, Clewell RA, et al. Dose-response modeling of etoposide-induced DNA damage response. Toxicol Sci. 2014 Feb;137(2):371-384. PMID: 24241721.

 

Zhang F, Koh GY, Hollingsworth J, et al. Reformulation of etoposide with solubility-enhancing rubusoside. Int J Pharm. 2012 Sep 15;434(1-2):453-459. PMID: 22698860." Xn, Carc., Xi Not dangerous goods.

LKT F1669 Ferulic Acid 5 g 33.2 Hydroxycinnamic acid found in various plant sources, metabolite of verbascoside. 3-(4-Hydroxy-3-methoxyphenyl)-2-propenoic acid Caffeic acid 3-methyl ether; 4-Hydroxy-3-methoxy- cinnamic acid 1135-24-6 ≥98% 194.18 C10H10O4 COC1=C(C=CC(=C1)C=CC(=O)O)O Ambient Ambient Soluble in hot water, or ethyl acetate.DMSO:39mg/mL, Ethanol:39mg/mL "Quirantes-Piné R, Herranz-López M, Funes L, et al. Phenylpropanoids and their metabolites are the major compounds responsible for blood-cell protection against oxidative stress after administration of Lippia citriodora in rats. Phytomedicine. 2013 Sep 15;20(12):1112-8. PMID: 23827667.

 

Xu Y, Zhang L, Shao T, et al. Ferulic acid increases pain threshold and ameliorates depression-like behaviors in reserpine-treated mice: behavioral and neurobiological analyses. Metab Brain Dis. 2013 Dec;28(4):571-83. PMID: 23584961.

 

Picone P, Nuzzo D, Di Carlo M. Ferulic acid: a natural antioxidant against oxidative stress induced by oligomeric A-beta on sea urchin embryo. Biol Bull. 2013 Feb;224(1):18-28. PMID: 23493505.

 

Lin TY, Lu CW, Huang SK, et al. Ferulic acid suppresses glutamate release through inhibition of voltage-dependent calcium entry in rat cerebrocortical nerve terminals. J Med Food. 2013 Feb;16(2):112-9. PMID: 23342970.

 

Choi R, Kim BH, Naowaboot J, et al. Effects of ferulic acid on diabetic nephropathy in a rat model of type 2 diabetes. Exp Mol Med. 2011 Dec 31;43(12):676-83. PMID: 21975281.

" Xi Not dangerous goods.

LKT F1669 Ferulic Acid 25 g 54.4 Hydroxycinnamic acid found in various plant sources, metabolite of verbascoside. 3-(4-Hydroxy-3-methoxyphenyl)-2-propenoic acid Caffeic acid 3-methyl ether; 4-Hydroxy-3-methoxy- cinnamic acid 1135-24-6 ≥98% 194.18 C10H10O4 COC1=C(C=CC(=C1)C=CC(=O)O)O Ambient Ambient Soluble in hot water, or ethyl acetate.DMSO:39mg/mL, Ethanol:39mg/mL "Quirantes-Piné R, Herranz-López M, Funes L, et al. Phenylpropanoids and their metabolites are the major compounds responsible for blood-cell protection against oxidative stress after administration of Lippia citriodora in rats. Phytomedicine. 2013 Sep 15;20(12):1112-8. PMID: 23827667.

 

Xu Y, Zhang L, Shao T, et al. Ferulic acid increases pain threshold and ameliorates depression-like behaviors in reserpine-treated mice: behavioral and neurobiological analyses. Metab Brain Dis. 2013 Dec;28(4):571-83. PMID: 23584961.

 

Picone P, Nuzzo D, Di Carlo M. Ferulic acid: a natural antioxidant against oxidative stress induced by oligomeric A-beta on sea urchin embryo. Biol Bull. 2013 Feb;224(1):18-28. PMID: 23493505.

 

Lin TY, Lu CW, Huang SK, et al. Ferulic acid suppresses glutamate release through inhibition of voltage-dependent calcium entry in rat cerebrocortical nerve terminals. J Med Food. 2013 Feb;16(2):112-9. PMID: 23342970.

 

Choi R, Kim BH, Naowaboot J, et al. Effects of ferulic acid on diabetic nephropathy in a rat model of type 2 diabetes. Exp Mol Med. 2011 Dec 31;43(12):676-83. PMID: 21975281.

" Xi Not dangerous goods.

LKT F4480 5-Fluorouracil 1 g 32.8 Pyrimidine analog; inhibits thymidylate synthase. 5-Fluoro-2,4(1H,3H)-pyrimidinedione Fluorouracil; 5-FU; 2,4-dioxo-5-fluoropyrimidine 51-21-8 ≥98% 130.08 C4H3FN2O2 C1=C(C(=O)NC(=O)N1)F Sensitive to light. Ambient Ambient Slightly soluble in water (12mg/mL). "Papanastasopoulos P, Stebbing J. Molecular basis of 5-fluorouracil-related toxicity: lessons from clinical practice. Anticancer Res. 2014 Apr;34(4):1531-5. PMID: 24692679.

 

Longley DB, Harkin DP, Johnston PG. 5-fluorouracil: mechanisms of action and clinical strategies. Nat Rev Cancer. 2003 May;3(5):330-8. PMID: 12724731.

" Xi, Xn, Repr. "UN number: 2811     Class:  6.1     Packing group:  III

Proper shipping name:  Toxic solids, organic, n.o.s. (Fluorouracil)

Reportable Quantity (RQ):  Marine pollutant:  No     Poison Inhalation Hazard:  No"

LKT F4480 5-Fluorouracil 5 g 85.4 Pyrimidine analog; inhibits thymidylate synthase. 5-Fluoro-2,4(1H,3H)-pyrimidinedione Fluorouracil; 5-FU; 2,4-dioxo-5-fluoropyrimidine 51-21-8 ≥98% 130.08 C4H3FN2O2 C1=C(C(=O)NC(=O)N1)F Sensitive to light. Ambient Ambient Slightly soluble in water (12mg/mL). "Papanastasopoulos P, Stebbing J. Molecular basis of 5-fluorouracil-related toxicity: lessons from clinical practice. Anticancer Res. 2014 Apr;34(4):1531-5. PMID: 24692679.

 

Longley DB, Harkin DP, Johnston PG. 5-fluorouracil: mechanisms of action and clinical strategies. Nat Rev Cancer. 2003 May;3(5):330-8. PMID: 12724731.

" Xi, Xn, Repr. "UN number: 2811     Class:  6.1     Packing group:  III

Proper shipping name:  Toxic solids, organic, n.o.s. (Fluorouracil)

Reportable Quantity (RQ):  Marine pollutant:  No     Poison Inhalation Hazard:  No"

LKT F4481 Flurbiprofen 1 g 49.2 NSAID; COX-1/2 inhibitor. 2-Fluoro-α-methyl[1,1'-biphenyl]-4-acetic acid Adfeed; Ansaid; Antadys; Cebutid; Froben; Flurofen 5104-49-4 ≥98% 244.26 C15H13FO2 CC(C1=CC(=C(C=C1)C2=CC=CC=C2)F)C(=O)O Ambient Ambient Slightly soluble in water (8mg/mL). "Sun B, Chen L, Wei X, et al. The Akt/GSK-3β pathway mediates flurbiprofen-induced neuroprotection against focal cerebral ischemia/reperfusion injury in rats. Biochem Biophys Res Commun. 2011 Jun 17;409(4):808-13. PMID: 21624354.

 

Jin H, Wang Z, Liu L, et al. R-flurbiprofen reverses multidrug resistance, proliferation and metastasis in gastric cancer cells by p75(NTR) induction. Mol Pharm. 2010 Feb 1;7(1):156-68. PMID: 19916560.

" T, Xi "UN number: 2811     Class:  6.1     Packing group:  III

Proper shipping name:  Toxic solids, organic, n.o.s. (Flurbiprofen)

Marine pollutant:  No     Poison inhalation hazard:  No"

LKT F4481 Flurbiprofen 5 g 176.4 NSAID; COX-1/2 inhibitor. 2-Fluoro-α-methyl[1,1'-biphenyl]-4-acetic acid Adfeed; Ansaid; Antadys; Cebutid; Froben; Flurofen 5104-49-4 ≥98% 244.26 C15H13FO2 CC(C1=CC(=C(C=C1)C2=CC=CC=C2)F)C(=O)O Ambient Ambient Slightly soluble in water (8mg/mL). "Sun B, Chen L, Wei X, et al. The Akt/GSK-3β pathway mediates flurbiprofen-induced neuroprotection against focal cerebral ischemia/reperfusion injury in rats. Biochem Biophys Res Commun. 2011 Jun 17;409(4):808-13. PMID: 21624354.

 

Jin H, Wang Z, Liu L, et al. R-flurbiprofen reverses multidrug resistance, proliferation and metastasis in gastric cancer cells by p75(NTR) induction. Mol Pharm. 2010 Feb 1;7(1):156-68. PMID: 19916560.

" T, Xi "UN number: 2811     Class:  6.1     Packing group:  III

Proper shipping name:  Toxic solids, organic, n.o.s. (Flurbiprofen)

Marine pollutant:  No     Poison inhalation hazard:  No"

LKT F4481 Flurbiprofen 25 g 546 NSAID; COX-1/2 inhibitor. 2-Fluoro-α-methyl[1,1'-biphenyl]-4-acetic acid Adfeed; Ansaid; Antadys; Cebutid; Froben; Flurofen 5104-49-4 ≥98% 244.26 C15H13FO2 CC(C1=CC(=C(C=C1)C2=CC=CC=C2)F)C(=O)O Ambient Ambient Slightly soluble in water (8mg/mL). "Sun B, Chen L, Wei X, et al. The Akt/GSK-3β pathway mediates flurbiprofen-induced neuroprotection against focal cerebral ischemia/reperfusion injury in rats. Biochem Biophys Res Commun. 2011 Jun 17;409(4):808-13. PMID: 21624354.

 

Jin H, Wang Z, Liu L, et al. R-flurbiprofen reverses multidrug resistance, proliferation and metastasis in gastric cancer cells by p75(NTR) induction. Mol Pharm. 2010 Feb 1;7(1):156-68. PMID: 19916560.

" T, Xi "UN number: 2811     Class:  6.1     Packing group:  III

Proper shipping name:  Toxic solids, organic, n.o.s. (Flurbiprofen)

Marine pollutant:  No     Poison inhalation hazard:  No"

LKT F7657 Ftorafur 250 mg 78 5-fluorouracil prodrug, pyrimidine analog; thymidylate synthase inhibitor. 5-Fluoro-1-(tetrahydro-2-furanyl)-2,4(1H,3H)- pyrimidinedione Tegafur; Citofur; Furafluor; 5-Fluoro-1-(tetrahydro-2-furyl)uracil 17902-23-7 ≥98% 200.17 C8H9FN2O3 C1CC(OC1)N2C=C(C(=O)NC2=O)F Ambient Ambient Soluble in hot water, ethanol, methanol,or DMSO. "Fukushima M. Antitumor activity and function of S-1, a new oral tegafur-based formulation. Gan To Kagaku Ryoho. 2006 Jun;33 Suppl 1:19-26. PMID: 16897968.

 

Longley DB, Harkin DP, Johnston PG. 5-fluorouracil: mechanisms of action and clinical strategies. Nat Rev Cancer. 2003 May;3(5):330-8. PMID: 12724731.

 

Tanaka F, Fukuse T, Wada H, et al. The history, mechanism and clinical use of oral 5-fluorouracil derivative chemotherapeutic agents. Curr Pharm Biotechnol. 2000 Sep;1(2):137-64. PMID: 11467334.

" T "UN number: 2811     Class:  6.1     Packing group:  II

Proper shipping name:  Toxic solids, organic, n.o.s. (5-Fluoro--(tetrahydro-2-furyl)uracil)

Reportable quantity (RQ):    Marine pollutant:  No     Poison inhalation hazard:  No."

LKT F7657 Ftorafur 1 g 207 5-fluorouracil prodrug, pyrimidine analog; thymidylate synthase inhibitor. 5-Fluoro-1-(tetrahydro-2-furanyl)-2,4(1H,3H)- pyrimidinedione Tegafur; Citofur; Furafluor; 5-Fluoro-1-(tetrahydro-2-furyl)uracil 17902-23-7 ≥98% 200.17 C8H9FN2O3 C1CC(OC1)N2C=C(C(=O)NC2=O)F Ambient Ambient Soluble in hot water, ethanol, methanol,or DMSO. "Fukushima M. Antitumor activity and function of S-1, a new oral tegafur-based formulation. Gan To Kagaku Ryoho. 2006 Jun;33 Suppl 1:19-26. PMID: 16897968.

 

Longley DB, Harkin DP, Johnston PG. 5-fluorouracil: mechanisms of action and clinical strategies. Nat Rev Cancer. 2003 May;3(5):330-8. PMID: 12724731.

 

Tanaka F, Fukuse T, Wada H, et al. The history, mechanism and clinical use of oral 5-fluorouracil derivative chemotherapeutic agents. Curr Pharm Biotechnol. 2000 Sep;1(2):137-64. PMID: 11467334.

" T "UN number: 2811     Class:  6.1     Packing group:  II

Proper shipping name:  Toxic solids, organic, n.o.s. (5-Fluoro--(tetrahydro-2-furyl)uracil)

Reportable quantity (RQ):    Marine pollutant:  No     Poison inhalation hazard:  No."

LKT F8149 Fumonisin B1 1 mg 172.3 Mycotoxin produced by Fusarium; sphingosine acyltransferase inhibitor. 1,2,3-propanetricarboxylic acid 1,1'-[1-(12-amino- 4,9,11-trihydroxy-2-methyltridecyl)-2-(1-methyl- pentyl)-1,2-ethanediyl] ester Macrofusine; FB1 116355-83-0 ≥98% 721.83 C34H59NO15 CCCCC(C)C(C(CC(C)CC(CCCCC(CC(C(C)N)O)O)O)OC(=O)CC(CC(=O)O)C(=O)O)OC(=O)CC(CC(=O)O)C(=O)O Ambient -20°C Soluble in PBS (18 mg/ml), methanol (10 mg/ml), and acetonitrile (10 mg/ml) "Wei T, Zhu W, Pang M, et al. Natural occurrence of fumonisins B1 and B2 in corn in four provinces of China. Food Addit Contam Part B Surveill. 2013 Dec;6(4):270-4. PMID: 24779936.

 

Tardieu D, Bailly JD, Skiba F, et al. Chronic toxicity of fumonisins in turkeys. Poult Sci. 2007 Sep;86(9):1887-93. PMID: 17704375.

" Carc., Xi, F, Xn Not dangerous goods.

LKT F8149 Fumonisin B1 5 mg 657.7 Mycotoxin produced by Fusarium; sphingosine acyltransferase inhibitor. 1,2,3-propanetricarboxylic acid 1,1'-[1-(12-amino- 4,9,11-trihydroxy-2-methyltridecyl)-2-(1-methyl- pentyl)-1,2-ethanediyl] ester Macrofusine; FB1 116355-83-0 ≥98% 721.83 C34H59NO15 CCCCC(C)C(C(CC(C)CC(CCCCC(CC(C(C)N)O)O)O)OC(=O)CC(CC(=O)O)C(=O)O)OC(=O)CC(CC(=O)O)C(=O)O Ambient -20°C Soluble in PBS (18 mg/ml), methanol (10 mg/ml), and acetonitrile (10 mg/ml) "Wei T, Zhu W, Pang M, et al. Natural occurrence of fumonisins B1 and B2 in corn in four provinces of China. Food Addit Contam Part B Surveill. 2013 Dec;6(4):270-4. PMID: 24779936.

 

Tardieu D, Bailly JD, Skiba F, et al. Chronic toxicity of fumonisins in turkeys. Poult Sci. 2007 Sep;86(9):1887-93. PMID: 17704375.

" Carc., Xi, F, Xn Not dangerous goods.

LKT F8150 Fumonisin B2 1 mg 391.3 Mycotoxin produced by Fusarium; sphingosine acyltransferase inhibitor. FB2 116355-84-1 ≥97% 705.8 C34H59NO14 CCCCC(C)C(C(CC(C)CCCCCCC(CC(C(C)N)O)O)OC(=O)CC(CC(=O)O)C(=O)O)OC(=O)CC(CC(=O)O)C(=O)O Protect from light. Ambient -20°C Soluble in methanol. "Wei T, Zhu W, Pang M, et al. Natural occurrence of fumonisins B1 and B2 in corn in four provinces of China. Food Addit Contam Part B Surveill. 2013 Dec;6(4):270-4. PMID: 24779936.

 

Tardieu D, Bailly JD, Skiba F, et al. Chronic toxicity of fumonisins in turkeys. Poult Sci. 2007 Sep;86(9):1887-93. PMID: 17704375.

" Carc., Xi, T+ "UN number: 2811     Class:  6.1     Packing group:  I

Proper shipping name:  Toxic solids, organic, n.o.s. (Fumonisin B2)

Reportable Quantity (RQ):     Marine pollutant:  No     Poison inhalation hazard:  No"

LKT F8150 Fumonisin B2 5 mg 1638.9 Mycotoxin produced by Fusarium; sphingosine acyltransferase inhibitor. FB2 116355-84-1 ≥97% 705.8 C34H59NO14 CCCCC(C)C(C(CC(C)CCCCCCC(CC(C(C)N)O)O)OC(=O)CC(CC(=O)O)C(=O)O)OC(=O)CC(CC(=O)O)C(=O)O Protect from light. Ambient -20°C Soluble in methanol. "Wei T, Zhu W, Pang M, et al. Natural occurrence of fumonisins B1 and B2 in corn in four provinces of China. Food Addit Contam Part B Surveill. 2013 Dec;6(4):270-4. PMID: 24779936.

 

Tardieu D, Bailly JD, Skiba F, et al. Chronic toxicity of fumonisins in turkeys. Poult Sci. 2007 Sep;86(9):1887-93. PMID: 17704375.

" Carc., Xi, T+ "UN number: 2811     Class:  6.1     Packing group:  I

Proper shipping name:  Toxic solids, organic, n.o.s. (Fumonisin B2)

Reportable Quantity (RQ):     Marine pollutant:  No     Poison inhalation hazard:  No"

LKT G0145 Gallic Acid 10 g 30 Phenol found in various plant sources, used to determine phenol content of analytes. 3,4,5-Trihydroxybenzoic acid 149-91-7 ≥98% 170.12 C7H6O5 C1=C(C=C(C(=C1O)O)O)C(=O)O Ambient Ambient Soluble in ethanol or acetone. Slightly soluble in water (11.5 mg/ml).  DMSO, methanol. "Sun J, Li YZ, Ding YH, et al. Neuroprotective effects of gallic acid against hypoxia/reoxygenation-induced mitochondrial dysfunctions in vitro and cerebral ischemia/reperfusion injury in vivo. Brain Res. 2014 Sep 22. [Epub ahead of print]. PMID: 25251593.

 

Wang K, Zhu X, Zhang K, et al. Investigation of gallic Acid induced anticancer effect in human breast carcinoma mcf-7 cells. J Biochem Mol Toxicol. 2014 Sep;28(9):387-93. PMID: 24864015.

 

Luís Â, Silva F, Sousa S, et al. Antistaphylococcal and biofilm inhibitory activities of gallic, caffeic, and chlorogenic acids. Biofouling. 2014 Jan;30(1):69-79. PMID: 24228999.

 

Liang W, Li X, Li Y, et al. Gallic acid induces apoptosis and inhibits cell migration by upregulating miR-518b in SW1353 human chondrosarcoma cells. Int J Oncol. 2014 Jan;44(1):91-8. PMID: 24173143.

 

Sen S, Asokkumar K, Umamaheswari M, et al. Antiulcerogenic effect of gallic Acid in rats and its effect on oxidant and antioxidant parameters in stomach tissue. Indian J Pharm Sci. 2013 Mar;75(2):149-55. PMID: 24019562.

" Xi Not dangerous goods.

LKT G0145 Gallic Acid 100 g 44.6 Phenol found in various plant sources, used to determine phenol content of analytes. 3,4,5-Trihydroxybenzoic acid 149-91-7 ≥98% 170.12 C7H6O5 C1=C(C=C(C(=C1O)O)O)C(=O)O Ambient Ambient Soluble in ethanol or acetone. Slightly soluble in water (11.5 mg/ml).  DMSO, methanol. "Sun J, Li YZ, Ding YH, et al. Neuroprotective effects of gallic acid against hypoxia/reoxygenation-induced mitochondrial dysfunctions in vitro and cerebral ischemia/reperfusion injury in vivo. Brain Res. 2014 Sep 22. [Epub ahead of print]. PMID: 25251593.

 

Wang K, Zhu X, Zhang K, et al. Investigation of gallic Acid induced anticancer effect in human breast carcinoma mcf-7 cells. J Biochem Mol Toxicol. 2014 Sep;28(9):387-93. PMID: 24864015.

 

Luís Â, Silva F, Sousa S, et al. Antistaphylococcal and biofilm inhibitory activities of gallic, caffeic, and chlorogenic acids. Biofouling. 2014 Jan;30(1):69-79. PMID: 24228999.

 

Liang W, Li X, Li Y, et al. Gallic acid induces apoptosis and inhibits cell migration by upregulating miR-518b in SW1353 human chondrosarcoma cells. Int J Oncol. 2014 Jan;44(1):91-8. PMID: 24173143.

 

Sen S, Asokkumar K, Umamaheswari M, et al. Antiulcerogenic effect of gallic Acid in rats and its effect on oxidant and antioxidant parameters in stomach tissue. Indian J Pharm Sci. 2013 Mar;75(2):149-55. PMID: 24019562.

" Xi Not dangerous goods.

LKT G0145 Gallic Acid 500 g 107 Phenol found in various plant sources, used to determine phenol content of analytes. 3,4,5-Trihydroxybenzoic acid 149-91-7 ≥98% 170.12 C7H6O5 C1=C(C=C(C(=C1O)O)O)C(=O)O Ambient Ambient Soluble in ethanol or acetone. Slightly soluble in water (11.5 mg/ml).  DMSO, methanol. "Sun J, Li YZ, Ding YH, et al. Neuroprotective effects of gallic acid against hypoxia/reoxygenation-induced mitochondrial dysfunctions in vitro and cerebral ischemia/reperfusion injury in vivo. Brain Res. 2014 Sep 22. [Epub ahead of print]. PMID: 25251593.

 

Wang K, Zhu X, Zhang K, et al. Investigation of gallic Acid induced anticancer effect in human breast carcinoma mcf-7 cells. J Biochem Mol Toxicol. 2014 Sep;28(9):387-93. PMID: 24864015.

 

Luís Â, Silva F, Sousa S, et al. Antistaphylococcal and biofilm inhibitory activities of gallic, caffeic, and chlorogenic acids. Biofouling. 2014 Jan;30(1):69-79. PMID: 24228999.

 

Liang W, Li X, Li Y, et al. Gallic acid induces apoptosis and inhibits cell migration by upregulating miR-518b in SW1353 human chondrosarcoma cells. Int J Oncol. 2014 Jan;44(1):91-8. PMID: 24173143.

 

Sen S, Asokkumar K, Umamaheswari M, et al. Antiulcerogenic effect of gallic Acid in rats and its effect on oxidant and antioxidant parameters in stomach tissue. Indian J Pharm Sci. 2013 Mar;75(2):149-55. PMID: 24019562.

" Xi Not dangerous goods.

LKT G1652 Genistein 100 mg 45.3 Phytoestrogen, isoflavone found in various plant sources such as soy. 5,7-Dihydroxy-3-(4-hydroxyphenyl)-4H-1- benzopyran-4-one Prunetol; Genisteol 446-72-0 ≥98% 270.24 C15H10O5 C1=CC(=CC=C1C2=COC3=CC(=CC(=C3C2=O)O)O)O Ambient -20°C Soluble in acetone or methanol. DMSO to 100 mM, ethanol to 2 mg/mL. Insoluble in water. "Lee SH, Kim JK, Jang HD. Genistein inhibits osteoclastic differentiation of RAW 264.7 cells via regulation of ROS production and scavenging. Int J Mol Sci. 2014 Jun 12;15(6):10605-21. PMID: 24927148.

 

Wang S, Wei H, Cai M, et al. Genistein attenuates brain damage induced by transient cerebral ischemia through up-regulation of ERK activity in ovariectomized mice. Int J Biol Sci. 2014 Apr 8;10(4):457-65. PMID: 24719563.

 

Li J, Li J, Yue Y, et al. Genistein suppresses tumor necrosis factor α-induced inflammation via modulating reactive oxygen species/Akt/nuclear factor κB and adenosine monophosphate-activated protein kinase signal pathways in human synoviocyte MH7A cells. Drug Des Devel Ther. 2014 Mar 17;8:315-23. PMID: 24669186.

 

Wu J, Xu J, Han S, et al. Effects of genistein on apoptosis in HCT-116 human colon cancer cells and its mechanism. Wei Sheng Yan Jiu. 2014 Jan;43(1):1-5. PMID: 24564102.

 

Wang SD, Chen BC, Kao ST, et al. Genistein inhibits tumor invasion by suppressing multiple signal transduction pathways in human hepatocellular carcinoma cells. BMC Complement Altern Med. 2014 Jan 16;14:26. PMID: 24433534.

 

Fan P, Fan S, Wang H, et al. Genistein decreases the breast cancer stem-like cell population through Hedgehog pathway. Stem Cell Res Ther. 2013;4(6):146. PMID: 24331293.

 

Arunkumar E, Karthik D, Anuradha CV. Genistein sensitizes hepatic insulin signaling and modulates lipid regulatory genes through p70 ribosomal S6 kinase-1 inhibition in high-fat-high-fructose diet-fed mice. Pharm Biol. 2013 Jul;51(7):815-24. PMID: 23627466.

 

Luo S, Lan T, Liao W, et al. Genistein inhibits Aβ₂₅₋₃₅ -induced neurotoxicity in PC12 cells via PKC signaling pathway. Neurochem Res. 2012 Dec;37(12):2787-94. PMID: 22949092.

" Xi Not dangerous goods.

LKT G1652 Genistein 500 mg 168.2 Phytoestrogen, isoflavone found in various plant sources such as soy. 5,7-Dihydroxy-3-(4-hydroxyphenyl)-4H-1- benzopyran-4-one Prunetol; Genisteol 446-72-0 ≥98% 270.24 C15H10O5 C1=CC(=CC=C1C2=COC3=CC(=CC(=C3C2=O)O)O)O Ambient -20°C Soluble in acetone or methanol. DMSO to 100 mM, ethanol to 2 mg/mL. Insoluble in water. "Lee SH, Kim JK, Jang HD. Genistein inhibits osteoclastic differentiation of RAW 264.7 cells via regulation of ROS production and scavenging. Int J Mol Sci. 2014 Jun 12;15(6):10605-21. PMID: 24927148.

 

Wang S, Wei H, Cai M, et al. Genistein attenuates brain damage induced by transient cerebral ischemia through up-regulation of ERK activity in ovariectomized mice. Int J Biol Sci. 2014 Apr 8;10(4):457-65. PMID: 24719563.

 

Li J, Li J, Yue Y, et al. Genistein suppresses tumor necrosis factor α-induced inflammation via modulating reactive oxygen species/Akt/nuclear factor κB and adenosine monophosphate-activated protein kinase signal pathways in human synoviocyte MH7A cells. Drug Des Devel Ther. 2014 Mar 17;8:315-23. PMID: 24669186.

 

Wu J, Xu J, Han S, et al. Effects of genistein on apoptosis in HCT-116 human colon cancer cells and its mechanism. Wei Sheng Yan Jiu. 2014 Jan;43(1):1-5. PMID: 24564102.

 

Wang SD, Chen BC, Kao ST, et al. Genistein inhibits tumor invasion by suppressing multiple signal transduction pathways in human hepatocellular carcinoma cells. BMC Complement Altern Med. 2014 Jan 16;14:26. PMID: 24433534.

 

Fan P, Fan S, Wang H, et al. Genistein decreases the breast cancer stem-like cell population through Hedgehog pathway. Stem Cell Res Ther. 2013;4(6):146. PMID: 24331293.

 

Arunkumar E, Karthik D, Anuradha CV. Genistein sensitizes hepatic insulin signaling and modulates lipid regulatory genes through p70 ribosomal S6 kinase-1 inhibition in high-fat-high-fructose diet-fed mice. Pharm Biol. 2013 Jul;51(7):815-24. PMID: 23627466.

 

Luo S, Lan T, Liao W, et al. Genistein inhibits Aβ₂₅₋₃₅ -induced neurotoxicity in PC12 cells via PKC signaling pathway. Neurochem Res. 2012 Dec;37(12):2787-94. PMID: 22949092.

" Xi Not dangerous goods.

LKT G1652 Genistein 1 g 300.7 Phytoestrogen, isoflavone found in various plant sources such as soy. 5,7-Dihydroxy-3-(4-hydroxyphenyl)-4H-1- benzopyran-4-one Prunetol; Genisteol 446-72-0 ≥98% 270.24 C15H10O5 C1=CC(=CC=C1C2=COC3=CC(=CC(=C3C2=O)O)O)O Ambient -20°C Soluble in acetone or methanol. DMSO to 100 mM, ethanol to 2 mg/mL. Insoluble in water. "Lee SH, Kim JK, Jang HD. Genistein inhibits osteoclastic differentiation of RAW 264.7 cells via regulation of ROS production and scavenging. Int J Mol Sci. 2014 Jun 12;15(6):10605-21. PMID: 24927148.

 

Wang S, Wei H, Cai M, et al. Genistein attenuates brain damage induced by transient cerebral ischemia through up-regulation of ERK activity in ovariectomized mice. Int J Biol Sci. 2014 Apr 8;10(4):457-65. PMID: 24719563.

 

Li J, Li J, Yue Y, et al. Genistein suppresses tumor necrosis factor α-induced inflammation via modulating reactive oxygen species/Akt/nuclear factor κB and adenosine monophosphate-activated protein kinase signal pathways in human synoviocyte MH7A cells. Drug Des Devel Ther. 2014 Mar 17;8:315-23. PMID: 24669186.

 

Wu J, Xu J, Han S, et al. Effects of genistein on apoptosis in HCT-116 human colon cancer cells and its mechanism. Wei Sheng Yan Jiu. 2014 Jan;43(1):1-5. PMID: 24564102.

 

Wang SD, Chen BC, Kao ST, et al. Genistein inhibits tumor invasion by suppressing multiple signal transduction pathways in human hepatocellular carcinoma cells. BMC Complement Altern Med. 2014 Jan 16;14:26. PMID: 24433534.

 

Fan P, Fan S, Wang H, et al. Genistein decreases the breast cancer stem-like cell population through Hedgehog pathway. Stem Cell Res Ther. 2013;4(6):146. PMID: 24331293.

 

Arunkumar E, Karthik D, Anuradha CV. Genistein sensitizes hepatic insulin signaling and modulates lipid regulatory genes through p70 ribosomal S6 kinase-1 inhibition in high-fat-high-fructose diet-fed mice. Pharm Biol. 2013 Jul;51(7):815-24. PMID: 23627466.

 

Luo S, Lan T, Liao W, et al. Genistein inhibits Aβ₂₅₋₃₅ -induced neurotoxicity in PC12 cells via PKC signaling pathway. Neurochem Res. 2012 Dec;37(12):2787-94. PMID: 22949092.

" Xi Not dangerous goods.

LKT G4597 18β-Glycyrrhetinic Acid 5 g 62.9 Triterpene glycoside found in Glycyrrhiza; 15-HPGDH inhibitor, hERG and KCNA3/Kv1.3 K+ channel blocker. (3β,20β)-3-Hydroxy-11-oxoolean-12-en-29-oic acid Enoxolone; Uralenic acid; Arthrodont; Biosone 471-53-4 ≥98% 470.68 C30H46O4 CC1(C2CCC3(C(C2(CCC1O)C)C(=O)C=C4C3(CCC5(C4CC(CC5)(C)C(=O)O)C)C)C)C Ambient Ambient Soluble in ethanol, chloroform, dioxone, pyridine or acetic acid. "Jayasooriya RG, Dilshara MG, Park SR, et al. 18β-Glycyrrhetinic acid suppresses TNF-α induced matrix metalloproteinase-9 and vascular endothelial growth factor by suppressing the Akt-dependent NF-κB pathway. Toxicol In Vitro. 2014 Aug;28(5):751-8. PMID: 24613819.

 

Park M, Lee JH, Choi JK, et al. 18β-glycyrrhetinic acid attenuates anandamide-induced adiposity and high-fat diet induced obesity. Mol Nutr Food Res. 2014 Jul;58(7):1436-46. PMID: 24687644.

 

Song J, Ko HS, Sohn EJ, et al. Inhibition of protein kinase C α/βII and activation of c-Jun NH2-terminal kinase mediate glycyrrhetinic acid induced apoptosis in non-small cell lung cancer NCI-H460 cells. Bioorg Med Chem Lett. 2014 Feb 15;24(4):1188-91. PMID: 24461294.

 

Wu D, Jiang L, Wu H, et al. Inhibitory effects of glycyrrhetinic Acid on the delayed rectifier potassium current in Guinea pig ventricular myocytes and HERG channel. Evid Based Complement Alternat Med. 2013;2013:481830. PMID: 24069049.

 

Fu XX, Du LL, Zhao N, et al. 18β-Glycyrrhetinic acid potently inhibits Kv1.3 potassium channels and T cell activation in human Jurkat T cells. J Ethnopharmacol. 2013 Jul 9;148(2):647-54. PMID: 23707333.

" Xn, Xi Not dangerous goods.

LKT G4597 18β-Glycyrrhetinic Acid 10 g 100.7 Triterpene glycoside found in Glycyrrhiza; 15-HPGDH inhibitor, hERG and KCNA3/Kv1.3 K+ channel blocker. (3β,20β)-3-Hydroxy-11-oxoolean-12-en-29-oic acid Enoxolone; Uralenic acid; Arthrodont; Biosone 471-53-4 ≥98% 470.68 C30H46O4 CC1(C2CCC3(C(C2(CCC1O)C)C(=O)C=C4C3(CCC5(C4CC(CC5)(C)C(=O)O)C)C)C)C Ambient Ambient Soluble in ethanol, chloroform, dioxone, pyridine or acetic acid. "Jayasooriya RG, Dilshara MG, Park SR, et al. 18β-Glycyrrhetinic acid suppresses TNF-α induced matrix metalloproteinase-9 and vascular endothelial growth factor by suppressing the Akt-dependent NF-κB pathway. Toxicol In Vitro. 2014 Aug;28(5):751-8. PMID: 24613819.

 

Park M, Lee JH, Choi JK, et al. 18β-glycyrrhetinic acid attenuates anandamide-induced adiposity and high-fat diet induced obesity. Mol Nutr Food Res. 2014 Jul;58(7):1436-46. PMID: 24687644.

 

Song J, Ko HS, Sohn EJ, et al. Inhibition of protein kinase C α/βII and activation of c-Jun NH2-terminal kinase mediate glycyrrhetinic acid induced apoptosis in non-small cell lung cancer NCI-H460 cells. Bioorg Med Chem Lett. 2014 Feb 15;24(4):1188-91. PMID: 24461294.

 

Wu D, Jiang L, Wu H, et al. Inhibitory effects of glycyrrhetinic Acid on the delayed rectifier potassium current in Guinea pig ventricular myocytes and HERG channel. Evid Based Complement Alternat Med. 2013;2013:481830. PMID: 24069049.

 

Fu XX, Du LL, Zhao N, et al. 18β-Glycyrrhetinic acid potently inhibits Kv1.3 potassium channels and T cell activation in human Jurkat T cells. J Ethnopharmacol. 2013 Jul 9;148(2):647-54. PMID: 23707333.

" Xn, Xi Not dangerous goods.

LKT G4597 18β-Glycyrrhetinic Acid 25 g 188.8 Triterpene glycoside found in Glycyrrhiza; 15-HPGDH inhibitor, hERG and KCNA3/Kv1.3 K+ channel blocker. (3β,20β)-3-Hydroxy-11-oxoolean-12-en-29-oic acid Enoxolone; Uralenic acid; Arthrodont; Biosone 471-53-4 ≥98% 470.68 C30H46O4 CC1(C2CCC3(C(C2(CCC1O)C)C(=O)C=C4C3(CCC5(C4CC(CC5)(C)C(=O)O)C)C)C)C Ambient Ambient Soluble in ethanol, chloroform, dioxone, pyridine or acetic acid. "Jayasooriya RG, Dilshara MG, Park SR, et al. 18β-Glycyrrhetinic acid suppresses TNF-α induced matrix metalloproteinase-9 and vascular endothelial growth factor by suppressing the Akt-dependent NF-κB pathway. Toxicol In Vitro. 2014 Aug;28(5):751-8. PMID: 24613819.

 

Park M, Lee JH, Choi JK, et al. 18β-glycyrrhetinic acid attenuates anandamide-induced adiposity and high-fat diet induced obesity. Mol Nutr Food Res. 2014 Jul;58(7):1436-46. PMID: 24687644.

 

Song J, Ko HS, Sohn EJ, et al. Inhibition of protein kinase C α/βII and activation of c-Jun NH2-terminal kinase mediate glycyrrhetinic acid induced apoptosis in non-small cell lung cancer NCI-H460 cells. Bioorg Med Chem Lett. 2014 Feb 15;24(4):1188-91. PMID: 24461294.

 

Wu D, Jiang L, Wu H, et al. Inhibitory effects of glycyrrhetinic Acid on the delayed rectifier potassium current in Guinea pig ventricular myocytes and HERG channel. Evid Based Complement Alternat Med. 2013;2013:481830. PMID: 24069049.

 

Fu XX, Du LL, Zhao N, et al. 18β-Glycyrrhetinic acid potently inhibits Kv1.3 potassium channels and T cell activation in human Jurkat T cells. J Ethnopharmacol. 2013 Jul 9;148(2):647-54. PMID: 23707333.

" Xn, Xi Not dangerous goods.

LKT G4598 Glycyrrhizic Acid Ammonium Trihydrate 10 g 41.3 Triterpene glycoside found in Glycyrrhiza; 11β-hydroxysteroid dehydrogenase inhibitor. (3β,20β)-20-Carboxy-11-oxo-30-norolean-2-en-3-yl 2-O-β-D-glucopyranuronosyl-a-D-glucopyranosiduronic acid Glycyrrhizin; glycyrrhizinic acid; glycyrrhetinic acid glycoside 53956-04-0 ≥93% 894.03 C42H65NO16 3H2O CC1(C2CCC3(C(C2(CCC1OC4C(C(C(C(O4)C(=O)O)O)O)OC5C(C(C(C(O5)C(=O)O)O)O)O)C)C(=O)C=C6C3(CCC7(C6CC(CC7)(C)C(=O)O)C)C)C)C.N Stored under inert gas Ambient Ambient Soluble in hot water or ethanol. "Ye S, Zhu Y, Ming Y, et al. Glycyrrhizin protects mice against renal ischemia-reperfusion injury through inhibition of apoptosis and inflammation by downregulating p38 mitogen-activated protein kinase signaling. Exp Ther Med. 2014 May;7(5):1247-1252. PMID: 24940420.

 

Son M, Lee M, Sung GH, et al. Bioactive activities of natural products against herpesvirus infection. J Microbiol. 2013 Oct;51(5):545-51. Erratum in: J Microbiol. 2013 Dec;51(6):888.  PMID: 24173639.

 

Luo L, Jin Y, Kim ID, et al. Glycyrrhizin attenuates kainic Acid-induced neuronal cell death in the mouse hippocampus. Exp Neurobiol. 2013 Jun;22(2):107-15. PMID: 23833559.

 

Feng L, Zhu MM, Zhang MH, et al. Protection of glycyrrhizic acid against AGEs-induced endothelial dysfunction through inhibiting RAGE/NF-κB pathway activation in human umbilical vein endothelial cells. J Ethnopharmacol. 2013 Jun 21;148(1):27-36. PMID: 23528363.

 

Khan R, Khan AQ, Lateef A, et al. Glycyrrhizic acid suppresses the development of precancerous lesions via regulating the hyperproliferation, inflammation, angiogenesis and apoptosis in the colon of Wistar rats. PLoS One. 2013;8(2):e56020. PMID: 23457494.

 

Shetty AV, Thirugnanam S, Dakshinamoorthy G, et al. 18α-glycyrrhetinic acid targets prostate cancer cells by down-regulating inflammation-related genes. Int J Oncol. 2011 Sep;39(3):635-40. PMID: 21637916.

 

Michaelis M, Geiler J, Naczk P, et al. Glycyrrhizin exerts antioxidative effects in H5N1 influenza A virus-infected cells and inhibits virus replication and pro-inflammatory gene expression. PLoS One. 2011;6(5):e19705. PMID: 21611183.

 

Wolkerstorfer A, Kurz H, Bachhofner N, et al. Glycyrrhizin inhibits influenza A virus uptake into the cell. Antiviral Res. 2009 Aug;83(2):171-8. PMID: 19416738.

" Not dangerous goods.

LKT G4598 Glycyrrhizic Acid Ammonium Trihydrate 25 g 80.9 Triterpene glycoside found in Glycyrrhiza; 11β-hydroxysteroid dehydrogenase inhibitor. (3β,20β)-20-Carboxy-11-oxo-30-norolean-2-en-3-yl 2-O-β-D-glucopyranuronosyl-a-D-glucopyranosiduronic acid Glycyrrhizin; glycyrrhizinic acid; glycyrrhetinic acid glycoside 53956-04-0 ≥93% 894.03 C42H65NO16 3H2O CC1(C2CCC3(C(C2(CCC1OC4C(C(C(C(O4)C(=O)O)O)O)OC5C(C(C(C(O5)C(=O)O)O)O)O)C)C(=O)C=C6C3(CCC7(C6CC(CC7)(C)C(=O)O)C)C)C)C.N Stored under inert gas Ambient Ambient Soluble in hot water or ethanol. "Ye S, Zhu Y, Ming Y, et al. Glycyrrhizin protects mice against renal ischemia-reperfusion injury through inhibition of apoptosis and inflammation by downregulating p38 mitogen-activated protein kinase signaling. Exp Ther Med. 2014 May;7(5):1247-1252. PMID: 24940420.

 

Son M, Lee M, Sung GH, et al. Bioactive activities of natural products against herpesvirus infection. J Microbiol. 2013 Oct;51(5):545-51. Erratum in: J Microbiol. 2013 Dec;51(6):888.  PMID: 24173639.

 

Luo L, Jin Y, Kim ID, et al. Glycyrrhizin attenuates kainic Acid-induced neuronal cell death in the mouse hippocampus. Exp Neurobiol. 2013 Jun;22(2):107-15. PMID: 23833559.

 

Feng L, Zhu MM, Zhang MH, et al. Protection of glycyrrhizic acid against AGEs-induced endothelial dysfunction through inhibiting RAGE/NF-κB pathway activation in human umbilical vein endothelial cells. J Ethnopharmacol. 2013 Jun 21;148(1):27-36. PMID: 23528363.

 

Khan R, Khan AQ, Lateef A, et al. Glycyrrhizic acid suppresses the development of precancerous lesions via regulating the hyperproliferation, inflammation, angiogenesis and apoptosis in the colon of Wistar rats. PLoS One. 2013;8(2):e56020. PMID: 23457494.

 

Shetty AV, Thirugnanam S, Dakshinamoorthy G, et al. 18α-glycyrrhetinic acid targets prostate cancer cells by down-regulating inflammation-related genes. Int J Oncol. 2011 Sep;39(3):635-40. PMID: 21637916.

 

Michaelis M, Geiler J, Naczk P, et al. Glycyrrhizin exerts antioxidative effects in H5N1 influenza A virus-infected cells and inhibits virus replication and pro-inflammatory gene expression. PLoS One. 2011;6(5):e19705. PMID: 21611183.

 

Wolkerstorfer A, Kurz H, Bachhofner N, et al. Glycyrrhizin inhibits influenza A virus uptake into the cell. Antiviral Res. 2009 Aug;83(2):171-8. PMID: 19416738.

" Not dangerous goods.

LKT G6817 Green Tea Polyphenols 10 g 83.5 Extract containing catechins and flavonoids found in Camilla sinensis (green tea). Tea Polyphenols 84650-60-2 ≥95% Resistant to acid, and heat-stable (boiling for 4 hr.- lost only 2% antioxidant activity) Ambient 4°C Soluble in water. "Reygaert WC. The antimicrobial possibilities of green tea. Front Microbiol. 2014 Aug 20;5:434. PMID: 25191312.

 

Li MJ, Yin YC, Wang J, et al. Green tea compounds in breast cancer prevention and treatment. World J Clin Oncol. 2014 Aug 10;5(3):520-8. PMID: 25114865.

 

Kim HS, Quon MJ, Kim JA. New insights into the mechanisms of polyphenols beyond antioxidant properties; lessons from the green tea polyphenol, epigallocatechin 3-gallate. Redox Biol. 2014 Jan 10;2:187-95. PMID: 24494192.

 

Wang S, Moustaid-Moussa N, Chen L, et al. Novel insights of dietary polyphenols and obesity. J Nutr Biochem. 2014 Jan;25(1):1-18. PMID: 24314860.

 

Oz HS, Chen T, de Villiers WJ. Green tea polyphenols and sulfasalazine have parallel anti-inflammatory properties in colitis models. Front Immunol. 2013 Jun 5;4:132. PMID: 23761791.

 

Strong R, Miller RA, Astle CM, et al. Evaluation of resveratrol, green tea extract, curcumin, oxaloacetic acid, and mediu-chain triglyceride oil on life span of genetically heterogeneous mice. J Gerontol A Biol Sci Med Sci. 2013 Jan;68(1):6-16. PMID: 22451473." Not dangerous goods.

LKT G6817 Green Tea Polyphenols 20 g 144.5 Extract containing catechins and flavonoids found in Camilla sinensis (green tea). Tea Polyphenols 84650-60-2 ≥95% Resistant to acid, and heat-stable (boiling for 4 hr.- lost only 2% antioxidant activity) Ambient 4°C Soluble in water. "Reygaert WC. The antimicrobial possibilities of green tea. Front Microbiol. 2014 Aug 20;5:434. PMID: 25191312.

 

Li MJ, Yin YC, Wang J, et al. Green tea compounds in breast cancer prevention and treatment. World J Clin Oncol. 2014 Aug 10;5(3):520-8. PMID: 25114865.

 

Kim HS, Quon MJ, Kim JA. New insights into the mechanisms of polyphenols beyond antioxidant properties; lessons from the green tea polyphenol, epigallocatechin 3-gallate. Redox Biol. 2014 Jan 10;2:187-95. PMID: 24494192.

 

Wang S, Moustaid-Moussa N, Chen L, et al. Novel insights of dietary polyphenols and obesity. J Nutr Biochem. 2014 Jan;25(1):1-18. PMID: 24314860.

 

Oz HS, Chen T, de Villiers WJ. Green tea polyphenols and sulfasalazine have parallel anti-inflammatory properties in colitis models. Front Immunol. 2013 Jun 5;4:132. PMID: 23761791.

 

Strong R, Miller RA, Astle CM, et al. Evaluation of resveratrol, green tea extract, curcumin, oxaloacetic acid, and mediu-chain triglyceride oil on life span of genetically heterogeneous mice. J Gerontol A Biol Sci Med Sci. 2013 Jan;68(1):6-16. PMID: 22451473." Not dangerous goods.

LKT G6817 Green Tea Polyphenols 100 g 535 Extract containing catechins and flavonoids found in Camilla sinensis (green tea). Tea Polyphenols 84650-60-2 ≥95% Resistant to acid, and heat-stable (boiling for 4 hr.- lost only 2% antioxidant activity) Ambient 4°C Soluble in water. "Reygaert WC. The antimicrobial possibilities of green tea. Front Microbiol. 2014 Aug 20;5:434. PMID: 25191312.

 

Li MJ, Yin YC, Wang J, et al. Green tea compounds in breast cancer prevention and treatment. World J Clin Oncol. 2014 Aug 10;5(3):520-8. PMID: 25114865.

 

Kim HS, Quon MJ, Kim JA. New insights into the mechanisms of polyphenols beyond antioxidant properties; lessons from the green tea polyphenol, epigallocatechin 3-gallate. Redox Biol. 2014 Jan 10;2:187-95. PMID: 24494192.

 

Wang S, Moustaid-Moussa N, Chen L, et al. Novel insights of dietary polyphenols and obesity. J Nutr Biochem. 2014 Jan;25(1):1-18. PMID: 24314860.

 

Oz HS, Chen T, de Villiers WJ. Green tea polyphenols and sulfasalazine have parallel anti-inflammatory properties in colitis models. Front Immunol. 2013 Jun 5;4:132. PMID: 23761791.

 

Strong R, Miller RA, Astle CM, et al. Evaluation of resveratrol, green tea extract, curcumin, oxaloacetic acid, and mediu-chain triglyceride oil on life span of genetically heterogeneous mice. J Gerontol A Biol Sci Med Sci. 2013 Jan;68(1):6-16. PMID: 22451473." Not dangerous goods.

LKT H0169 Harringtonine 5 mg 121.4 Cephalotaxine alkaloid originally found in Cephalotaxus; ribosomal protein synthesis inhibitor. "Cephalotaxine, 4-methyl (2R)-2-hydroxy-2-(3-hydroxy-3-

methylbutyl)butanedioate (ester) (9CI)" 26833-85-2 ≥97% 531.59 C28H37NO9 CC(C)(CCC(CC(=O)OC)(C(=O)OC1C2C3=CC4=C(C=C3CCN5C2(CCC5)C=C1OC)OCO4)O)O Light sensitive.  Ambient -20°C Does not mix well with water. Soluble in DMSO to 100 mM and in ethanol to 50 mM. "Wu C, Shen H, Xia D. Harringtonine induces apoptosis in NB4 cells through down-regulation of Mcl-1. Zhejiang Da Xue Xue Bao Yi Xue Ban. 2013 Jul;42(4):431-6. PMID: 24022932.

 

Kaur P, Thiruchelvan M, Lee RC, et al. Inhibition of chikungunya virus replication by harringtonine, a novel antiviral that suppresses viral protein expression. Antimicrob Agents Chemother. 2013 Jan;57(1):155-67. PMID: 23275491.

 

Ingolia NT, Brar GA, Rouskin S, et al. The ribosome profiling strategy for monitoring translation in vivo by deep sequencing of ribosome-protected mRNA fragments. Nat Protoc. 2012 Jul 26;7(8):1534-50. PMID: 22836135.

 

Cai YX, Meng FY, Sun QX, et al. In vitro effect of bortezomib alone or in combination with harringtonine or arsenic trioxide on proliferation and apoptosis of multidrug resistant leukemia cells. Zhonghua Xue Ye Xue Za Zhi. 2008 Nov;29(11):737-40. PMID: 19176009.

 

Zhang C, Li Y, Ma H, et al. Simultaneous multi-parameter observation of Harringtonine-treating HL-60 cells with both two-photon and confocal laser scanning microscopy. Sci China C Life Sci. 2001 Aug;44(4):383-91. PMID: 18726419.

 

Fresno M, Jiménez A, Vázquez D. Inhibition of translation in eukaryotic systems by harringtonine. Eur J Biochem. 1977 Jan;72(2):323-30. PMID: 319998.

" Not dangerous goods.

LKT H0169 Harringtonine 10 mg 208.7 Cephalotaxine alkaloid originally found in Cephalotaxus; ribosomal protein synthesis inhibitor. "Cephalotaxine, 4-methyl (2R)-2-hydroxy-2-(3-hydroxy-3-

methylbutyl)butanedioate (ester) (9CI)" 26833-85-2 ≥97% 531.59 C28H37NO9 CC(C)(CCC(CC(=O)OC)(C(=O)OC1C2C3=CC4=C(C=C3CCN5C2(CCC5)C=C1OC)OCO4)O)O Light sensitive.  Ambient -20°C Does not mix well with water. Soluble in DMSO to 100 mM and in ethanol to 50 mM. "Wu C, Shen H, Xia D. Harringtonine induces apoptosis in NB4 cells through down-regulation of Mcl-1. Zhejiang Da Xue Xue Bao Yi Xue Ban. 2013 Jul;42(4):431-6. PMID: 24022932.

 

Kaur P, Thiruchelvan M, Lee RC, et al. Inhibition of chikungunya virus replication by harringtonine, a novel antiviral that suppresses viral protein expression. Antimicrob Agents Chemother. 2013 Jan;57(1):155-67. PMID: 23275491.

 

Ingolia NT, Brar GA, Rouskin S, et al. The ribosome profiling strategy for monitoring translation in vivo by deep sequencing of ribosome-protected mRNA fragments. Nat Protoc. 2012 Jul 26;7(8):1534-50. PMID: 22836135.

 

Cai YX, Meng FY, Sun QX, et al. In vitro effect of bortezomib alone or in combination with harringtonine or arsenic trioxide on proliferation and apoptosis of multidrug resistant leukemia cells. Zhonghua Xue Ye Xue Za Zhi. 2008 Nov;29(11):737-40. PMID: 19176009.

 

Zhang C, Li Y, Ma H, et al. Simultaneous multi-parameter observation of Harringtonine-treating HL-60 cells with both two-photon and confocal laser scanning microscopy. Sci China C Life Sci. 2001 Aug;44(4):383-91. PMID: 18726419.

 

Fresno M, Jiménez A, Vázquez D. Inhibition of translation in eukaryotic systems by harringtonine. Eur J Biochem. 1977 Jan;72(2):323-30. PMID: 319998.

" Not dangerous goods.

LKT H0169 Harringtonine 25 mg 406.5 Cephalotaxine alkaloid originally found in Cephalotaxus; ribosomal protein synthesis inhibitor. "Cephalotaxine, 4-methyl (2R)-2-hydroxy-2-(3-hydroxy-3-

methylbutyl)butanedioate (ester) (9CI)" 26833-85-2 ≥97% 531.59 C28H37NO9 CC(C)(CCC(CC(=O)OC)(C(=O)OC1C2C3=CC4=C(C=C3CCN5C2(CCC5)C=C1OC)OCO4)O)O Light sensitive.  Ambient -20°C Does not mix well with water. Soluble in DMSO to 100 mM and in ethanol to 50 mM. "Wu C, Shen H, Xia D. Harringtonine induces apoptosis in NB4 cells through down-regulation of Mcl-1. Zhejiang Da Xue Xue Bao Yi Xue Ban. 2013 Jul;42(4):431-6. PMID: 24022932.

 

Kaur P, Thiruchelvan M, Lee RC, et al. Inhibition of chikungunya virus replication by harringtonine, a novel antiviral that suppresses viral protein expression. Antimicrob Agents Chemother. 2013 Jan;57(1):155-67. PMID: 23275491.

 

Ingolia NT, Brar GA, Rouskin S, et al. The ribosome profiling strategy for monitoring translation in vivo by deep sequencing of ribosome-protected mRNA fragments. Nat Protoc. 2012 Jul 26;7(8):1534-50. PMID: 22836135.

 

Cai YX, Meng FY, Sun QX, et al. In vitro effect of bortezomib alone or in combination with harringtonine or arsenic trioxide on proliferation and apoptosis of multidrug resistant leukemia cells. Zhonghua Xue Ye Xue Za Zhi. 2008 Nov;29(11):737-40. PMID: 19176009.

 

Zhang C, Li Y, Ma H, et al. Simultaneous multi-parameter observation of Harringtonine-treating HL-60 cells with both two-photon and confocal laser scanning microscopy. Sci China C Life Sci. 2001 Aug;44(4):383-91. PMID: 18726419.

 

Fresno M, Jiménez A, Vázquez D. Inhibition of translation in eukaryotic systems by harringtonine. Eur J Biochem. 1977 Jan;72(2):323-30. PMID: 319998.

" Not dangerous goods.

LKT H1660 2-n-Heptylfuran 10 g 165.5 Furan derivative produced in cooked meat. 2-Heptylfuran 2-Heptyl-furan 3777-71-7 ≥98% 166.27 C11H18O CCCCCCCC1=CC=CO1 Ambient 4°C Lam LK, Zheng BL. Inhibitory effects of 2-n-heptylfuran and 2-n-butylthiophene on benzo[a]pyrene-induced lung and forestomach tumorigenesis in A/J mice. Nutr Cancer. 1992;17(1):19-26. PMID: 1574441. Not dangerous goods.

LKT H1660 2-n-Heptylfuran 20 g 302.8 Furan derivative produced in cooked meat. 2-Heptylfuran 2-Heptyl-furan 3777-71-7 ≥98% 166.27 C11H18O CCCCCCCC1=CC=CO1 Ambient 4°C Lam LK, Zheng BL. Inhibitory effects of 2-n-heptylfuran and 2-n-butylthiophene on benzo[a]pyrene-induced lung and forestomach tumorigenesis in A/J mice. Nutr Cancer. 1992;17(1):19-26. PMID: 1574441. Not dangerous goods.

LKT H1672 Hesperetin 1 g 25.2 Flavanone found in species of Citrus; L-type Ca2+ channel blocker. (2S)-2,3-Dihydro-5,7-dihydroxy-2-(3-hydroxy-4- methoxyphenyl)-4H-1-benzopyran-4-one 3',5,7-trihydroxy-4'-methoxyflavanone; Cyanidanon 4'-methyl ether 1626 520-33-2 ≥95% 302.28 C16H14O6 COC1=C(C=C(C=C1)C2CC(=O)C3=C(C=C(C=C3O2)O)O)O Ambient -20°C Soluble in ethanol.  Slightly soluble in water. "Palit S, Kar S, Sharma G, et al. Hesperetin induces apoptosis in breast carcinoma by triggering accumulation of ROS and activation of ASK1/JNK pathway. J Cell Physiol. 2014 Sep 10. [Epub ahead of print]. PMID: 25204891.

 

Aswar M, Kute P, Mahajan S, et al. Protective effect of hesperetin in rat model of partial sciatic nerve ligation induced painful neuropathic pain: an evidence of anti-inflammatory and anti-oxidative activity. Pharmacol Biochem Behav. 2014 Sep;124:101-7. PMID: 24871567.

 

Liu Y, Niu L, Cui L, et al. Hesperetin inhibits rat coronary constriction by inhibiting Ca(2+) influx and enhancing voltage-gated K(+) channel currents of the myocytes. Eur J Pharmacol. 2014 Jul 15;735:193-201. PMID: 24751712.

 

Patel PN, Yu XM, Jaskula-Sztul R, et al. Hesperetin Activates the Notch1 Signaling Cascade, Causes Apoptosis, and Induces Cellular Differentiation in Anaplastic Thyroid Cancer. Ann Surg Oncol. 2014 Jan 14. [Epub ahead of print]. PMID: 24419754.

 

Deng W, Jiang D, Fang Y, et al. Hesperetin protects against cardiac remodelling induced by pressure overload in mice. J Mol Histol. 2013 Oct;44(5):575-85. PMID: 23719775.

 

Wang J, Zhu H, Yang Z, et al. Antioxidative effects of hesperetin against lead acetate-induced oxidative stress in rats. Indian J Pharmacol. 2013 Jul-Aug;45(4):395-8. PMID: 24014918.

 

Yang Y, Wolfram J, Shen H, et al. Hesperetin: an inhibitor of the transforming growth factor-β (TGF-β) signaling pathway. Eur J Med Chem. 2012 Dec;58:390-5. PMID: 23153811.

" Xi Not dangerous goods.

LKT H1672 Hesperetin 5 g 81.6 Flavanone found in species of Citrus; L-type Ca2+ channel blocker. (2S)-2,3-Dihydro-5,7-dihydroxy-2-(3-hydroxy-4- methoxyphenyl)-4H-1-benzopyran-4-one 3',5,7-trihydroxy-4'-methoxyflavanone; Cyanidanon 4'-methyl ether 1626 520-33-2 ≥95% 302.28 C16H14O6 COC1=C(C=C(C=C1)C2CC(=O)C3=C(C=C(C=C3O2)O)O)O Ambient -20°C Soluble in ethanol.  Slightly soluble in water. "Palit S, Kar S, Sharma G, et al. Hesperetin induces apoptosis in breast carcinoma by triggering accumulation of ROS and activation of ASK1/JNK pathway. J Cell Physiol. 2014 Sep 10. [Epub ahead of print]. PMID: 25204891.

 

Aswar M, Kute P, Mahajan S, et al. Protective effect of hesperetin in rat model of partial sciatic nerve ligation induced painful neuropathic pain: an evidence of anti-inflammatory and anti-oxidative activity. Pharmacol Biochem Behav. 2014 Sep;124:101-7. PMID: 24871567.

 

Liu Y, Niu L, Cui L, et al. Hesperetin inhibits rat coronary constriction by inhibiting Ca(2+) influx and enhancing voltage-gated K(+) channel currents of the myocytes. Eur J Pharmacol. 2014 Jul 15;735:193-201. PMID: 24751712.

 

Patel PN, Yu XM, Jaskula-Sztul R, et al. Hesperetin Activates the Notch1 Signaling Cascade, Causes Apoptosis, and Induces Cellular Differentiation in Anaplastic Thyroid Cancer. Ann Surg Oncol. 2014 Jan 14. [Epub ahead of print]. PMID: 24419754.

 

Deng W, Jiang D, Fang Y, et al. Hesperetin protects against cardiac remodelling induced by pressure overload in mice. J Mol Histol. 2013 Oct;44(5):575-85. PMID: 23719775.

 

Wang J, Zhu H, Yang Z, et al. Antioxidative effects of hesperetin against lead acetate-induced oxidative stress in rats. Indian J Pharmacol. 2013 Jul-Aug;45(4):395-8. PMID: 24014918.

 

Yang Y, Wolfram J, Shen H, et al. Hesperetin: an inhibitor of the transforming growth factor-β (TGF-β) signaling pathway. Eur J Med Chem. 2012 Dec;58:390-5. PMID: 23153811.

" Xi Not dangerous goods.

LKT H1672 Hesperetin 10 g 136 Flavanone found in species of Citrus; L-type Ca2+ channel blocker. (2S)-2,3-Dihydro-5,7-dihydroxy-2-(3-hydroxy-4- methoxyphenyl)-4H-1-benzopyran-4-one 3',5,7-trihydroxy-4'-methoxyflavanone; Cyanidanon 4'-methyl ether 1626 520-33-2 ≥95% 302.28 C16H14O6 COC1=C(C=C(C=C1)C2CC(=O)C3=C(C=C(C=C3O2)O)O)O Ambient -20°C Soluble in ethanol.  Slightly soluble in water. "Palit S, Kar S, Sharma G, et al. Hesperetin induces apoptosis in breast carcinoma by triggering accumulation of ROS and activation of ASK1/JNK pathway. J Cell Physiol. 2014 Sep 10. [Epub ahead of print]. PMID: 25204891.

 

Aswar M, Kute P, Mahajan S, et al. Protective effect of hesperetin in rat model of partial sciatic nerve ligation induced painful neuropathic pain: an evidence of anti-inflammatory and anti-oxidative activity. Pharmacol Biochem Behav. 2014 Sep;124:101-7. PMID: 24871567.

 

Liu Y, Niu L, Cui L, et al. Hesperetin inhibits rat coronary constriction by inhibiting Ca(2+) influx and enhancing voltage-gated K(+) channel currents of the myocytes. Eur J Pharmacol. 2014 Jul 15;735:193-201. PMID: 24751712.

 

Patel PN, Yu XM, Jaskula-Sztul R, et al. Hesperetin Activates the Notch1 Signaling Cascade, Causes Apoptosis, and Induces Cellular Differentiation in Anaplastic Thyroid Cancer. Ann Surg Oncol. 2014 Jan 14. [Epub ahead of print]. PMID: 24419754.

 

Deng W, Jiang D, Fang Y, et al. Hesperetin protects against cardiac remodelling induced by pressure overload in mice. J Mol Histol. 2013 Oct;44(5):575-85. PMID: 23719775.

 

Wang J, Zhu H, Yang Z, et al. Antioxidative effects of hesperetin against lead acetate-induced oxidative stress in rats. Indian J Pharmacol. 2013 Jul-Aug;45(4):395-8. PMID: 24014918.

 

Yang Y, Wolfram J, Shen H, et al. Hesperetin: an inhibitor of the transforming growth factor-β (TGF-β) signaling pathway. Eur J Med Chem. 2012 Dec;58:390-5. PMID: 23153811.

" Xi Not dangerous goods.

LKT H1673 Hesperidin 25 g 27.9 Flavonoid found in species of Citrus; COX-2 inhibitor. (2S)-7-[[6-O-(6-Deoxy-α-L-mannopyranosyl)-β-D- glucopyranosyl]oxy]-2,3-dihydro-5-hydroxy-2-(3- hydroxy-4-methoxyphenyl)-4H-1-benzopyran-4-one Hesperetin 7-rhamnoglucoside; Cirantin; Hesperetin-7- rutinoside 520-26-3 ≥95% 610.56 C28H34O15 CC1C(C(C(C(O1)OCC2C(C(C(C(O2)OC3=CC(=C4C(=O)CC(OC4=C3)C5=CC(=C(C=C5)OC)O)O)O)O)O)O)O)O Ambient Ambient Insoluble in water.  Soluble in DMF and DMSO  (30 mg/mL). Slightly soluble in ethanol and methanol (~1 mg/mL). "Guzmán-Gutiérrez SL, Navarrete A. Pharmacological exploration of the sedative mechanism of hesperidin identified as the active principle of Citrus sinensis flowers. Planta Med. 2009 Mar;75(4):295-301. PMID: 19219759.

 

Loscalzo LM, Wasowski C, Paladini AC, et al. Opioid receptors are involved in the sedative and antinociceptive effects of hesperidin as well as in its potentiation with benzodiazepines. Eur J Pharmacol. 2008 Feb 12;580(3):306-13. PMID: 18048026.

 

Hirata A, Murakami Y, Shoji M, et al. Kinetics of radical-scavenging activity of hesperetin and hesperidin and their inhibitory activity on COX-2 expression. Anticancer Res. 2005 Sep-Oct;25(5):3367-74. PMID: 16101151.

 

Chiba H, Uehara M, Wu J, et al. Hesperidin, a citrus flavonoid, inhibits bone loss and decreases serum and hepatic lipids in ovariectomized mice. J Nutr. 2003 Jun;133(6):1892-7. PMID: 12771335.

 

Monforte MT, Trovato A, Kirjavainen S, et al. Biological effects of hesperidin, a Citrus flavonoid. (note II): hypolipidemic activity on experimental hypercholesterolemia in rat. Farmaco. 1995 Sep;50(9):595-9. PMID: 7495469.

 

Emim JA, Oliveira AB, Lapa AJ. Pharmacological evaluation of the anti-inflammatory activity of a citrus bioflavonoid, hesperidin, and the isoflavonoids, duartin and claussequinone, in rats and mice. J Pharm Pharmacol. 1994 Feb;46(2):118-22. PMID: 8021799." Xn, Xi Not dangerous goods.

LKT H1673 Hesperidin 100 g 67.8 Flavonoid found in species of Citrus; COX-2 inhibitor. (2S)-7-[[6-O-(6-Deoxy-α-L-mannopyranosyl)-β-D- glucopyranosyl]oxy]-2,3-dihydro-5-hydroxy-2-(3- hydroxy-4-methoxyphenyl)-4H-1-benzopyran-4-one Hesperetin 7-rhamnoglucoside; Cirantin; Hesperetin-7- rutinoside 520-26-3 ≥95% 610.56 C28H34O15 CC1C(C(C(C(O1)OCC2C(C(C(C(O2)OC3=CC(=C4C(=O)CC(OC4=C3)C5=CC(=C(C=C5)OC)O)O)O)O)O)O)O)O Ambient Ambient Insoluble in water.  Soluble in DMF and DMSO  (30 mg/mL). Slightly soluble in ethanol and methanol (~1 mg/mL). "Guzmán-Gutiérrez SL, Navarrete A. Pharmacological exploration of the sedative mechanism of hesperidin identified as the active principle of Citrus sinensis flowers. Planta Med. 2009 Mar;75(4):295-301. PMID: 19219759.

 

Loscalzo LM, Wasowski C, Paladini AC, et al. Opioid receptors are involved in the sedative and antinociceptive effects of hesperidin as well as in its potentiation with benzodiazepines. Eur J Pharmacol. 2008 Feb 12;580(3):306-13. PMID: 18048026.

 

Hirata A, Murakami Y, Shoji M, et al. Kinetics of radical-scavenging activity of hesperetin and hesperidin and their inhibitory activity on COX-2 expression. Anticancer Res. 2005 Sep-Oct;25(5):3367-74. PMID: 16101151.

 

Chiba H, Uehara M, Wu J, et al. Hesperidin, a citrus flavonoid, inhibits bone loss and decreases serum and hepatic lipids in ovariectomized mice. J Nutr. 2003 Jun;133(6):1892-7. PMID: 12771335.

 

Monforte MT, Trovato A, Kirjavainen S, et al. Biological effects of hesperidin, a Citrus flavonoid. (note II): hypolipidemic activity on experimental hypercholesterolemia in rat. Farmaco. 1995 Sep;50(9):595-9. PMID: 7495469.

 

Emim JA, Oliveira AB, Lapa AJ. Pharmacological evaluation of the anti-inflammatory activity of a citrus bioflavonoid, hesperidin, and the isoflavonoids, duartin and claussequinone, in rats and mice. J Pharm Pharmacol. 1994 Feb;46(2):118-22. PMID: 8021799." Xn, Xi Not dangerous goods.

LKT H1695 S-Hexylglutathione 100 mg 84.3 Glutathione-S-transferase inhibitor. [1-carboxy-3-[[1-(carboxymethylcarbamoyl)-2- hexylsulfanyl-ethyl]carbamoyl]propyl]ammonium 24425-56-7 ≥98% 391.5 C16H29N3O6S CCCCCCSCC(C(=O)NCC(=O)O)NC(=O)CCC(C(=O)O)N Ambient 4°C "Imaizumi N, Aniya Y. The role of a membrane-bound glutathione transferase in the peroxynitrite-induced mitochondrial permeability transition pore: formation of a disulfide-linked protein complex. Arch Biochem Biophys. 2011 Dec 15;516(2):160-72. PMID: 22050912.

 

Ulziikhishig E, Lee KK, Hossain QS, et al. Inhibition of mitochondrial membrane bound-glutathione transferase by mitochondrial permeability transition inhibitors including cyclosporin A. Life Sci. 2010 May 8;86(19-20):726-32. PMID: 20226794.

" Not dangerous goods.

LKT H1695 S-Hexylglutathione 250 mg 140.7 Glutathione-S-transferase inhibitor. [1-carboxy-3-[[1-(carboxymethylcarbamoyl)-2- hexylsulfanyl-ethyl]carbamoyl]propyl]ammonium 24425-56-7 ≥98% 391.5 C16H29N3O6S CCCCCCSCC(C(=O)NCC(=O)O)NC(=O)CCC(C(=O)O)N Ambient 4°C "Imaizumi N, Aniya Y. The role of a membrane-bound glutathione transferase in the peroxynitrite-induced mitochondrial permeability transition pore: formation of a disulfide-linked protein complex. Arch Biochem Biophys. 2011 Dec 15;516(2):160-72. PMID: 22050912.

 

Ulziikhishig E, Lee KK, Hossain QS, et al. Inhibition of mitochondrial membrane bound-glutathione transferase by mitochondrial permeability transition inhibitors including cyclosporin A. Life Sci. 2010 May 8;86(19-20):726-32. PMID: 20226794.

" Not dangerous goods.

LKT H1695 S-Hexylglutathione 1 g 433.5 Glutathione-S-transferase inhibitor. [1-carboxy-3-[[1-(carboxymethylcarbamoyl)-2- hexylsulfanyl-ethyl]carbamoyl]propyl]ammonium 24425-56-7 ≥98% 391.5 C16H29N3O6S CCCCCCSCC(C(=O)NCC(=O)O)NC(=O)CCC(C(=O)O)N Ambient 4°C "Imaizumi N, Aniya Y. The role of a membrane-bound glutathione transferase in the peroxynitrite-induced mitochondrial permeability transition pore: formation of a disulfide-linked protein complex. Arch Biochem Biophys. 2011 Dec 15;516(2):160-72. PMID: 22050912.

 

Ulziikhishig E, Lee KK, Hossain QS, et al. Inhibition of mitochondrial membrane bound-glutathione transferase by mitochondrial permeability transition inhibitors including cyclosporin A. Life Sci. 2010 May 8;86(19-20):726-32. PMID: 20226794.

" Not dangerous goods.

LKT H5748 D,L-Homocysteine Thiolactone Hydrochloride 50 g 75.5 Heterocyclic derivative of cysteine, alters protein function. "(+-)-Dihydro-3-amino-2(3H)-thiophenone hydrochloride 

" 6038-19-3 ≥98% 153.63 C4H7NOS HCl C1CSC(=O)C1N.Cl Ambient Ambient Soluble in water. "Hrnčić D, Rašić-Marković A, Macut D, et al. Homocysteine thiolactone-induced seizures in adult rats are aggravated by inhibition of inducible nitric oxide synthase. Hum Exp Toxicol. 2014 May;33(5):496-503. PMID: 23760255.

 

Genoud V, Lauricella AM, Kordich LC, et al. Impact of homocysteine-thiolactone on plasma fibrin networks. J Thromb Thrombolysis. 2014 Mar 23. [Epub ahead of print]. PMID: 24659173.

 

Zivkovic V, Jakovljevic V, Pechanova O, et al. Effects of DL-homocysteine thiolactone on cardiac contractility, coronary flow, and oxidative stress markers in the isolated rat heart: the role of different gasotransmitters. Biomed Res Int. 2013;2013:318471. PMID: 24350259.

 

Borowczyk K, Shih DM, Jakubowski H. Metabolism and neurotoxicity of homocysteine thiolactone in mice: evidence for a protective role of paraoxonase 1. J Alzheimers Dis. 2012;30(2):225-31. PMID: 22406444.

" Not dangerous goods.

LKT H5748 D,L-Homocysteine Thiolactone Hydrochloride 100 g 104.2 Heterocyclic derivative of cysteine, alters protein function. "(+-)-Dihydro-3-amino-2(3H)-thiophenone hydrochloride 

" 6038-19-3 ≥98% 153.63 C4H7NOS HCl C1CSC(=O)C1N.Cl Ambient Ambient Soluble in water. "Hrnčić D, Rašić-Marković A, Macut D, et al. Homocysteine thiolactone-induced seizures in adult rats are aggravated by inhibition of inducible nitric oxide synthase. Hum Exp Toxicol. 2014 May;33(5):496-503. PMID: 23760255.

 

Genoud V, Lauricella AM, Kordich LC, et al. Impact of homocysteine-thiolactone on plasma fibrin networks. J Thromb Thrombolysis. 2014 Mar 23. [Epub ahead of print]. PMID: 24659173.

 

Zivkovic V, Jakovljevic V, Pechanova O, et al. Effects of DL-homocysteine thiolactone on cardiac contractility, coronary flow, and oxidative stress markers in the isolated rat heart: the role of different gasotransmitters. Biomed Res Int. 2013;2013:318471. PMID: 24350259.

 

Borowczyk K, Shih DM, Jakubowski H. Metabolism and neurotoxicity of homocysteine thiolactone in mice: evidence for a protective role of paraoxonase 1. J Alzheimers Dis. 2012;30(2):225-31. PMID: 22406444.

" Not dangerous goods.

LKT H5750 Homoharringtonine 1 mg 40.7 Alkaloid found in Cephalotaxus; ribosomal protein synthesis inhibitor. 26833-87-4 ≥97% 545.62 C29H39NO9 CC(C)(CCCC(CC(=O)OC)(C(=O)OC1C2C3=CC4=C(C=C3CCN5C2(CCC5)C=C1OC)OCO4)O)O Ambient -20°C "Gandhi V, Plunkett W, Cortes JE. Omacetaxine: a protein translation inhibitor for treatment of chronic myelogenous leukemia. Clin Cancer Res. 2014 Apr 1;20(7):1735-40. PMID: 24501394.

 

Daver N, Vega-Ruiz A, Kantarjian HM, et al. A phase II open-label study of the intravenous administration of homoharringtonine in the treatment of myelodysplastic syndrome. Eur J Cancer Care (Engl). 2013 Sep;22(5):605-11. PMID: 23701251.

 

Li YF, Deng Z, Din BH, et al. Effect of homoharringtonine on bone marrow CD34 + CD117 + cells in patients with chronic myelogenous leukemia. Leuk Lymphoma. 2012 May;53(5):934-9. PMID: 22054289.

" T+, Xi "UN number: 1544     Class: 6.1     Packing Group: II

Proper shipping name: Alkaloids, solid, n.o.s. (Homoharringtonine)"

LKT H5750 Homoharringtonine 5 mg 156.2 Alkaloid found in Cephalotaxus; ribosomal protein synthesis inhibitor. 26833-87-4 ≥97% 545.62 C29H39NO9 CC(C)(CCCC(CC(=O)OC)(C(=O)OC1C2C3=CC4=C(C=C3CCN5C2(CCC5)C=C1OC)OCO4)O)O Ambient -20°C "Gandhi V, Plunkett W, Cortes JE. Omacetaxine: a protein translation inhibitor for treatment of chronic myelogenous leukemia. Clin Cancer Res. 2014 Apr 1;20(7):1735-40. PMID: 24501394.

 

Daver N, Vega-Ruiz A, Kantarjian HM, et al. A phase II open-label study of the intravenous administration of homoharringtonine in the treatment of myelodysplastic syndrome. Eur J Cancer Care (Engl). 2013 Sep;22(5):605-11. PMID: 23701251.

 

Li YF, Deng Z, Din BH, et al. Effect of homoharringtonine on bone marrow CD34 + CD117 + cells in patients with chronic myelogenous leukemia. Leuk Lymphoma. 2012 May;53(5):934-9. PMID: 22054289.

" T+, Xi "UN number: 1544     Class: 6.1     Packing Group: II

Proper shipping name: Alkaloids, solid, n.o.s. (Homoharringtonine)"

LKT H5750 Homoharringtonine 10 mg 183.4 Alkaloid found in Cephalotaxus; ribosomal protein synthesis inhibitor. 26833-87-4 ≥97% 545.62 C29H39NO9 CC(C)(CCCC(CC(=O)OC)(C(=O)OC1C2C3=CC4=C(C=C3CCN5C2(CCC5)C=C1OC)OCO4)O)O Ambient -20°C "Gandhi V, Plunkett W, Cortes JE. Omacetaxine: a protein translation inhibitor for treatment of chronic myelogenous leukemia. Clin Cancer Res. 2014 Apr 1;20(7):1735-40. PMID: 24501394.

 

Daver N, Vega-Ruiz A, Kantarjian HM, et al. A phase II open-label study of the intravenous administration of homoharringtonine in the treatment of myelodysplastic syndrome. Eur J Cancer Care (Engl). 2013 Sep;22(5):605-11. PMID: 23701251.

 

Li YF, Deng Z, Din BH, et al. Effect of homoharringtonine on bone marrow CD34 + CD117 + cells in patients with chronic myelogenous leukemia. Leuk Lymphoma. 2012 May;53(5):934-9. PMID: 22054289.

" T+, Xi "UN number: 1544     Class: 6.1     Packing Group: II

Proper shipping name: Alkaloids, solid, n.o.s. (Homoharringtonine)"

LKT C0170 N-(4-Carbethoxyphenyl)retinamide 100 mg 45.3 Retinoid, differentiation inducer. 4-(Ethoxycarbophenyl)retinamide; N-(Carbo- ethoxyphenyl)retinamide 53839-71-7 ≥98% 447.62 C29H37NO3 CCOC(=O)C1=CC=C(C=C1)NC(=O)C=C(C)C=CC=C(C)C=CC2=C(CCCC2(C)C)C Ambient -20°C Soluble in DMSO or ethanol. "Han J. Highlights of the cancer chemoprevention studies in China. Prev Med. 1993 Sep;22(5):712-22. PMID: 8234211.

 

Song ZP, Liu YH, Han R. Differentiation of human promyelocytic leukemia (HL-60) cells induced by new synthetic retinoids 4-(ethoxycarbophenyl) retinamide and 4-(hydroxycarbophenyl) retinamide. Yao Xue Xue Bao. 1984 Aug;19(8):576-81. PMID: 6399190.

" Not dangerous goods.

LKT C0170 N-(4-Carbethoxyphenyl)retinamide 500 mg 155.4 Retinoid, differentiation inducer. 4-(Ethoxycarbophenyl)retinamide; N-(Carbo- ethoxyphenyl)retinamide 53839-71-7 ≥98% 447.62 C29H37NO3 CCOC(=O)C1=CC=C(C=C1)NC(=O)C=C(C)C=CC=C(C)C=CC2=C(CCCC2(C)C)C Ambient -20°C Soluble in DMSO or ethanol. "Han J. Highlights of the cancer chemoprevention studies in China. Prev Med. 1993 Sep;22(5):712-22. PMID: 8234211.

 

Song ZP, Liu YH, Han R. Differentiation of human promyelocytic leukemia (HL-60) cells induced by new synthetic retinoids 4-(ethoxycarbophenyl) retinamide and 4-(hydroxycarbophenyl) retinamide. Yao Xue Xue Bao. 1984 Aug;19(8):576-81. PMID: 6399190.

" Not dangerous goods.

LKT C0170 N-(4-Carbethoxyphenyl)retinamide 1 g 226.5 Retinoid, differentiation inducer. 4-(Ethoxycarbophenyl)retinamide; N-(Carbo- ethoxyphenyl)retinamide 53839-71-7 ≥98% 447.62 C29H37NO3 CCOC(=O)C1=CC=C(C=C1)NC(=O)C=C(C)C=CC=C(C)C=CC2=C(CCCC2(C)C)C Ambient -20°C Soluble in DMSO or ethanol. "Han J. Highlights of the cancer chemoprevention studies in China. Prev Med. 1993 Sep;22(5):712-22. PMID: 8234211.

 

Song ZP, Liu YH, Han R. Differentiation of human promyelocytic leukemia (HL-60) cells induced by new synthetic retinoids 4-(ethoxycarbophenyl) retinamide and 4-(hydroxycarbophenyl) retinamide. Yao Xue Xue Bao. 1984 Aug;19(8):576-81. PMID: 6399190.

" Not dangerous goods.

LKT I0416 Iberin 10 mg 151.8 ITC found in cruciferous vegetables, homolog of sulforaphane. 1-Isothiocyanato-3-(methylsufinyl) propane 3-Methylsulfinylpropyl isothiocyanate 505-44-2 ≥97% 163.26 C5H9NOS2 CS(=O)CCCN=C=S In ethanol at -20 stable for 2 years. Ambient -80°C Ethanol. DMSO to 11 mg/mL. DMF to 16 mg/mL. "Ernst IM, Palani K, Esatbeyoglu T, et al. Synthesis and Nrf2-inducing activity of the isothiocyanates iberverin, iberin and cheirolin. Pharmacol Res. 2013 Apr;70(1):155-62. PMID: 23403058.

 

Barrera LN, Cassidy A, Wang W, et al. TrxR1 and GPx2 are potently induced by isothiocyanates and selenium, and mutually cooperate to protect Caco-2 cells against free radical-mediated cell death. Biochim Biophys Acta. 2012 Oct;1823(10):1914-24. PMID: 22820176.

 

Traka MH, Chambers KF, Lund EK, et al. Involvement of KLF4 in sulforaphane- and iberin-mediated induction of p21(waf1/cip1). Nutr Cancer. 2009;61(1):137-45. PMID: 19116884.

 

Jadhav U, Ezhilarasan R, Vaughn SF, et al. Iberin induces cell cycle arrest and apoptosis in human neuroblastoma cells. Int J Mol Med. 2007 Mar;19(3):353-61. PMID: 17273780.

 

Jakobsen TH, Bragason SK, Phipps RK, et al. Food as a source for quorum sensing inhibitors: iberin frmo horseradish revealed as a quorum sensing inhibitor of Pseudomonas aeruginosa. Appl Environ Microbiol. 2012 Apr;78(7):2410-2421. PMID: 22286987.

" Not dangerous goods.

LKT I0416 Iberin 25 mg 357.9 ITC found in cruciferous vegetables, homolog of sulforaphane. 1-Isothiocyanato-3-(methylsufinyl) propane 3-Methylsulfinylpropyl isothiocyanate 505-44-2 ≥97% 163.26 C5H9NOS2 CS(=O)CCCN=C=S In ethanol at -20 stable for 2 years. Ambient -80°C Ethanol. DMSO to 11 mg/mL. DMF to 16 mg/mL. "Ernst IM, Palani K, Esatbeyoglu T, et al. Synthesis and Nrf2-inducing activity of the isothiocyanates iberverin, iberin and cheirolin. Pharmacol Res. 2013 Apr;70(1):155-62. PMID: 23403058.

 

Barrera LN, Cassidy A, Wang W, et al. TrxR1 and GPx2 are potently induced by isothiocyanates and selenium, and mutually cooperate to protect Caco-2 cells against free radical-mediated cell death. Biochim Biophys Acta. 2012 Oct;1823(10):1914-24. PMID: 22820176.

 

Traka MH, Chambers KF, Lund EK, et al. Involvement of KLF4 in sulforaphane- and iberin-mediated induction of p21(waf1/cip1). Nutr Cancer. 2009;61(1):137-45. PMID: 19116884.

 

Jadhav U, Ezhilarasan R, Vaughn SF, et al. Iberin induces cell cycle arrest and apoptosis in human neuroblastoma cells. Int J Mol Med. 2007 Mar;19(3):353-61. PMID: 17273780.

 

Jakobsen TH, Bragason SK, Phipps RK, et al. Food as a source for quorum sensing inhibitors: iberin frmo horseradish revealed as a quorum sensing inhibitor of Pseudomonas aeruginosa. Appl Environ Microbiol. 2012 Apr;78(7):2410-2421. PMID: 22286987.

" Not dangerous goods.

LKT I0416 Iberin 50 mg 570.5 ITC found in cruciferous vegetables, homolog of sulforaphane. 1-Isothiocyanato-3-(methylsufinyl) propane 3-Methylsulfinylpropyl isothiocyanate 505-44-2 ≥97% 163.26 C5H9NOS2 CS(=O)CCCN=C=S In ethanol at -20 stable for 2 years. Ambient -80°C Ethanol. DMSO to 11 mg/mL. DMF to 16 mg/mL. "Ernst IM, Palani K, Esatbeyoglu T, et al. Synthesis and Nrf2-inducing activity of the isothiocyanates iberverin, iberin and cheirolin. Pharmacol Res. 2013 Apr;70(1):155-62. PMID: 23403058.

 

Barrera LN, Cassidy A, Wang W, et al. TrxR1 and GPx2 are potently induced by isothiocyanates and selenium, and mutually cooperate to protect Caco-2 cells against free radical-mediated cell death. Biochim Biophys Acta. 2012 Oct;1823(10):1914-24. PMID: 22820176.

 

Traka MH, Chambers KF, Lund EK, et al. Involvement of KLF4 in sulforaphane- and iberin-mediated induction of p21(waf1/cip1). Nutr Cancer. 2009;61(1):137-45. PMID: 19116884.

 

Jadhav U, Ezhilarasan R, Vaughn SF, et al. Iberin induces cell cycle arrest and apoptosis in human neuroblastoma cells. Int J Mol Med. 2007 Mar;19(3):353-61. PMID: 17273780.

 

Jakobsen TH, Bragason SK, Phipps RK, et al. Food as a source for quorum sensing inhibitors: iberin frmo horseradish revealed as a quorum sensing inhibitor of Pseudomonas aeruginosa. Appl Environ Microbiol. 2012 Apr;78(7):2410-2421. PMID: 22286987.

" Not dangerous goods.

LKT I0416 Iberin 100 mg 1001.6 ITC found in cruciferous vegetables, homolog of sulforaphane. 1-Isothiocyanato-3-(methylsufinyl) propane 3-Methylsulfinylpropyl isothiocyanate 505-44-2 ≥97% 163.26 C5H9NOS2 CS(=O)CCCN=C=S In ethanol at -20 stable for 2 years. Ambient -80°C Ethanol. DMSO to 11 mg/mL. DMF to 16 mg/mL. "Ernst IM, Palani K, Esatbeyoglu T, et al. Synthesis and Nrf2-inducing activity of the isothiocyanates iberverin, iberin and cheirolin. Pharmacol Res. 2013 Apr;70(1):155-62. PMID: 23403058.

 

Barrera LN, Cassidy A, Wang W, et al. TrxR1 and GPx2 are potently induced by isothiocyanates and selenium, and mutually cooperate to protect Caco-2 cells against free radical-mediated cell death. Biochim Biophys Acta. 2012 Oct;1823(10):1914-24. PMID: 22820176.

 

Traka MH, Chambers KF, Lund EK, et al. Involvement of KLF4 in sulforaphane- and iberin-mediated induction of p21(waf1/cip1). Nutr Cancer. 2009;61(1):137-45. PMID: 19116884.

 

Jadhav U, Ezhilarasan R, Vaughn SF, et al. Iberin induces cell cycle arrest and apoptosis in human neuroblastoma cells. Int J Mol Med. 2007 Mar;19(3):353-61. PMID: 17273780.

 

Jakobsen TH, Bragason SK, Phipps RK, et al. Food as a source for quorum sensing inhibitors: iberin frmo horseradish revealed as a quorum sensing inhibitor of Pseudomonas aeruginosa. Appl Environ Microbiol. 2012 Apr;78(7):2410-2421. PMID: 22286987.

" Not dangerous goods.

LKT N1656 D-(+)-Neopterin 10 mg 64.2 Endogenous pteridine metabolite of GTP. 2-Amino-6-(1,2,3-trihydroxypropyl)-4(3H)-pteridinone Crithidia factor 2009-64-5 ≥98% 253.21 C9H11N5O4 C1=C(N=C2C(=N1)NC(=NC2=O)N)C(C(CO)O)O Protect from light. Ambient Ambient Soluble in 1N hydrogen chloride. "Ahmadzai H, Cameron B, Chui J, et al. Measurement of neopterin, TGF-β1 and ACE in the exhaled breath condensate of patients with sarcoidosis. J Breath Res. 2013 Dec;7(4):046003. PMID: 24091835.

 

Murr C, Widner B, Wirleitner B, et al. Neopterin as a marker for immune system activation. Curr Drug Metab. 2002 Apr;3(2):175-87. PMID: 12003349.

" Not dangerous goods.

LKT N1757 Neostigmine Bromide 250 mg 33.2 AChE inhibitor. 3-(N,N-Dimethylcarbamoyloxy)-N,N,N-trimethyl- anilinium bromide Prostigmine 114-80-7 ≥92% 303.2 C12H19BrN2O2 CN(C)C(=O)OC1=CC=CC(=C1)[N+](C)(C)C.[Br-] Ambient 4°C Soluble in water or ethanol. "Dahaba AA, Bornemann H, Hopfgartner E, et al. Effect of sugammadex or neostigmine neuromuscular block reversal on bispectral index monitoring of propofol/remifentanil anaesthesia. Br J Anaesth. 2012 Apr;108(4):602-6. PMID: 22315331.

 

Cellini J, Zaura Jukic AM, LePard KJ. Neostigmine-induced contraction and nitric oxide-induced relaxation of isolated ileum from STZ diabetic guinea pigs. Auton Neurosci. 2011 Dec 7;165(2):178-90. PMID: 21880552.

" T+ "UN number: 2811     Class: 6.1     Packing Group: II

Proper shipping name: Toxic solid, organic, n.o.s. (Neostigmine bromide)"

LKT N1757 Neostigmine Bromide 1 g 49.9 AChE inhibitor. 3-(N,N-Dimethylcarbamoyloxy)-N,N,N-trimethyl- anilinium bromide Prostigmine 114-80-7 ≥92% 303.2 C12H19BrN2O2 CN(C)C(=O)OC1=CC=CC(=C1)[N+](C)(C)C.[Br-] Ambient 4°C Soluble in water or ethanol. "Dahaba AA, Bornemann H, Hopfgartner E, et al. Effect of sugammadex or neostigmine neuromuscular block reversal on bispectral index monitoring of propofol/remifentanil anaesthesia. Br J Anaesth. 2012 Apr;108(4):602-6. PMID: 22315331.

 

Cellini J, Zaura Jukic AM, LePard KJ. Neostigmine-induced contraction and nitric oxide-induced relaxation of isolated ileum from STZ diabetic guinea pigs. Auton Neurosci. 2011 Dec 7;165(2):178-90. PMID: 21880552.

" T+ "UN number: 2811     Class: 6.1     Packing Group: II

Proper shipping name: Toxic solid, organic, n.o.s. (Neostigmine bromide)"

LKT A0025 17-Allylaminogeldanamycin 0.5 mg 40.7 Geldanamycin derivative; HSP90 inhibitor. 17-(Allylamino)-17-desmethoxy-geldanamycin; allylaminogeldanamycin; 17-AAG; telatinib. 75747-14-7 ≥97% 585.69 C31H43N3O8 CC1CC(C(C(C=C(C(C(C=CC=C(C(=O)NC2=CC(=O)C(=C(C1)C2=O)NCC=C)C)OC)OC(=O)N)C)C)O)OC Protect from light. Ambient 4°C Soluble in DMSO or methanol. "Thangjam GS, Dimitropoulou C, Joshi AD, et al. Novel mechanism of attenuation of LPS-induced NF-κB activation by the heat shock protein 90 inhibitor, 17-N-allylamino-17-demethoxygeldanamycin, in human lung microvascular endothelial cells. Am J Respir Cell Mol Biol. 2014 May;50(5):942-52. PMID: 24303801.

 

Powers MV, Valenti M, Miranda S, et al. Mode of cell death induced by the HSP90 inhibitor 17-AAG (tanespimycin) is dependent on the expression of pro-apoptotic BAX. Oncotarget. 2013 Nov;4(11):1963-75. PMID: 24185264.

 

Evers DL, Chao CF, Zhang Z, et al. 17-allylamino-17-(demethoxy)geldanamycin (17-AAG) is a potent and effective inhibitor of human cytomegalovirus replication in primary fibroblast cells. Arch Virol. 2012 Oct;157(10):1971-4. PMID: 22711259.

 

Gloesenkamp C, Nitzsche B, Lim AR, et al. Heat shock protein 90 is a promising target for effective growth inhibition of gastrointestinal neuroendocrine tumors. Int J Oncol. 2012 May;40(5):1659-67. PMID: 22246317." Not dangerous goods.

LKT A0025 17-Allylaminogeldanamycin 1 mg 47.6 Geldanamycin derivative; HSP90 inhibitor. 17-(Allylamino)-17-desmethoxy-geldanamycin; allylaminogeldanamycin; 17-AAG; telatinib. 75747-14-7 ≥97% 585.69 C31H43N3O8 CC1CC(C(C(C=C(C(C(C=CC=C(C(=O)NC2=CC(=O)C(=C(C1)C2=O)NCC=C)C)OC)OC(=O)N)C)C)O)OC Protect from light. Ambient 4°C Soluble in DMSO or methanol. "Thangjam GS, Dimitropoulou C, Joshi AD, et al. Novel mechanism of attenuation of LPS-induced NF-κB activation by the heat shock protein 90 inhibitor, 17-N-allylamino-17-demethoxygeldanamycin, in human lung microvascular endothelial cells. Am J Respir Cell Mol Biol. 2014 May;50(5):942-52. PMID: 24303801.

 

Powers MV, Valenti M, Miranda S, et al. Mode of cell death induced by the HSP90 inhibitor 17-AAG (tanespimycin) is dependent on the expression of pro-apoptotic BAX. Oncotarget. 2013 Nov;4(11):1963-75. PMID: 24185264.

 

Evers DL, Chao CF, Zhang Z, et al. 17-allylamino-17-(demethoxy)geldanamycin (17-AAG) is a potent and effective inhibitor of human cytomegalovirus replication in primary fibroblast cells. Arch Virol. 2012 Oct;157(10):1971-4. PMID: 22711259.

 

Gloesenkamp C, Nitzsche B, Lim AR, et al. Heat shock protein 90 is a promising target for effective growth inhibition of gastrointestinal neuroendocrine tumors. Int J Oncol. 2012 May;40(5):1659-67. PMID: 22246317." Not dangerous goods.

LKT A0099 A-779 1 mg 107.8 Mas antagonist. 159432-28-7 ≥95% 872.99 C39H60N12O11 Ambient -20°C "Tao X, Fan J, Kao G, et al. Angiotensin-(1-7) attenuates angiotensin II-induced signaling associated with activation of a tyrosine phosphatase in Sprague-Dawley rats cardiac fibroblasts. Biol Cell. 2014 Mar 18. [Epub ahead of print]. PMID: 24641355.

 

Santos RA, Campagnole-Santos MJ, Baracho NC, et al. Characterization of a new angiotensin antagonist selective for angiotensin-(1-7): evidence that the actions of angiotensin-(1-7) are mediated by specific angiotensin receptors. Brain Res Bull. 1994;35(4):293-8. PMID: 7850477.

" Not dangerous goods.

LKT A0099 A-779 2 mg 183 Mas antagonist. 159432-28-7 ≥95% 872.99 C39H60N12O11 Ambient -20°C "Tao X, Fan J, Kao G, et al. Angiotensin-(1-7) attenuates angiotensin II-induced signaling associated with activation of a tyrosine phosphatase in Sprague-Dawley rats cardiac fibroblasts. Biol Cell. 2014 Mar 18. [Epub ahead of print]. PMID: 24641355.

 

Santos RA, Campagnole-Santos MJ, Baracho NC, et al. Characterization of a new angiotensin antagonist selective for angiotensin-(1-7): evidence that the actions of angiotensin-(1-7) are mediated by specific angiotensin receptors. Brain Res Bull. 1994;35(4):293-8. PMID: 7850477.

" Not dangerous goods.

LKT A0099 A-779 5 mg 324 Mas antagonist. 159432-28-7 ≥95% 872.99 C39H60N12O11 Ambient -20°C "Tao X, Fan J, Kao G, et al. Angiotensin-(1-7) attenuates angiotensin II-induced signaling associated with activation of a tyrosine phosphatase in Sprague-Dawley rats cardiac fibroblasts. Biol Cell. 2014 Mar 18. [Epub ahead of print]. PMID: 24641355.

 

Santos RA, Campagnole-Santos MJ, Baracho NC, et al. Characterization of a new angiotensin antagonist selective for angiotensin-(1-7): evidence that the actions of angiotensin-(1-7) are mediated by specific angiotensin receptors. Brain Res Bull. 1994;35(4):293-8. PMID: 7850477.

" Not dangerous goods.

LKT A0101 4-bromo-A23187 1 mg 134.9 Non-fluorescent halogenated A23187 analog, Ca2+ ionophore. "

" 4-Bromo-A-23187, 4-BrA23187, 4-Bra23187 76455-82-8 ≥98% 602.52 C29H36BrN3O6 CC1CCC2(C(CC(C(O2)C(C)C(=O)C3=CC=CN3)C)C)OC1CC4=NC5=C(C(=C(C=C5O4)Br)NC)C(=O)O Ambient 4°C "Kim DY, Kang TB, Shim DW, et al. Emodin attenuates A23187-induced mast cell degranulation and tumor necrosis factor-α secretion through protein kinase C and IκB kinase 2 signaling. Eur J Pharmacol. 2014 Jan 15;723:501-6. PMID: 24239713.

 

Shang M, Zhang Q, Zhang MX, et al. Effects of endothelial microvesicles induced by A23187 on H9c2 cardiomyocytes. Zhongguo Ying Yong Sheng Li Xue Za Zhi. 2013 Nov;29(6):559-64. PMID: 24654540.

 

Tateno H, Krapf D, Hino T, et al. Ca2+ ionophore A23187 can make mouse spermatozoa capable of fertilizing in vitro without activation of cAMP-dependent phosphorylation pathways. Proc Natl Acad Sci U S A. 2013 Nov 12;110(46):18543-8. PMID: 24128762.

" Xn, Xi Not dangerous goods.

LKT A0101 4-bromo-A23187 5 mg 551.5 Non-fluorescent halogenated A23187 analog, Ca2+ ionophore. "

" 4-Bromo-A-23187, 4-BrA23187, 4-Bra23187 76455-82-8 ≥98% 602.52 C29H36BrN3O6 CC1CCC2(C(CC(C(O2)C(C)C(=O)C3=CC=CN3)C)C)OC1CC4=NC5=C(C(=C(C=C5O4)Br)NC)C(=O)O Ambient 4°C "Kim DY, Kang TB, Shim DW, et al. Emodin attenuates A23187-induced mast cell degranulation and tumor necrosis factor-α secretion through protein kinase C and IκB kinase 2 signaling. Eur J Pharmacol. 2014 Jan 15;723:501-6. PMID: 24239713.

 

Shang M, Zhang Q, Zhang MX, et al. Effects of endothelial microvesicles induced by A23187 on H9c2 cardiomyocytes. Zhongguo Ying Yong Sheng Li Xue Za Zhi. 2013 Nov;29(6):559-64. PMID: 24654540.

 

Tateno H, Krapf D, Hino T, et al. Ca2+ ionophore A23187 can make mouse spermatozoa capable of fertilizing in vitro without activation of cAMP-dependent phosphorylation pathways. Proc Natl Acad Sci U S A. 2013 Nov 12;110(46):18543-8. PMID: 24128762.

" Xn, Xi Not dangerous goods.

LKT A0102 A23187 Ca-Mg 5 mg 101.4 Ca2+ ionophore. ≥98%, TLC 523.62 (C29H36N3O6)2Mg  (C29H36N3O6)2Ca Ambient 4°C Insoluble in water, hexane. Slightly soluble in ethanol, methanol.  Soluble in choloform, acetone. "Kim DY, Kang TB, Shim DW, et al. Emodin attenuates A23187-induced mast cell degranulation and tumor necrosis factor-α secretion through protein kinase C and IκB kinase 2 signaling. Eur J Pharmacol. 2014 Jan 15;723:501-6. PMID: 24239713.

 

Shang M, Zhang Q, Zhang MX, et al. Effects of endothelial microvesicles induced by A23187 on H9c2 cardiomyocytes. Zhongguo Ying Yong Sheng Li Xue Za Zhi. 2013 Nov;29(6):559-64. PMID: 24654540.

 

Tateno H, Krapf D, Hino T, et al. Ca2+ ionophore A23187 can make mouse spermatozoa capable of fertilizing in vitro without activation of cAMP-dependent phosphorylation pathways. Proc Natl Acad Sci U S A. 2013 Nov 12;110(46):18543-8. PMID: 24128762.

" Not dangerous goods.

LKT A0102 A23187 Ca-Mg 10 mg 187.4 Ca2+ ionophore. ≥98%, TLC 523.62 (C29H36N3O6)2Mg  (C29H36N3O6)2Ca Ambient 4°C Insoluble in water, hexane. Slightly soluble in ethanol, methanol.  Soluble in choloform, acetone. "Kim DY, Kang TB, Shim DW, et al. Emodin attenuates A23187-induced mast cell degranulation and tumor necrosis factor-α secretion through protein kinase C and IκB kinase 2 signaling. Eur J Pharmacol. 2014 Jan 15;723:501-6. PMID: 24239713.

 

Shang M, Zhang Q, Zhang MX, et al. Effects of endothelial microvesicles induced by A23187 on H9c2 cardiomyocytes. Zhongguo Ying Yong Sheng Li Xue Za Zhi. 2013 Nov;29(6):559-64. PMID: 24654540.

 

Tateno H, Krapf D, Hino T, et al. Ca2+ ionophore A23187 can make mouse spermatozoa capable of fertilizing in vitro without activation of cAMP-dependent phosphorylation pathways. Proc Natl Acad Sci U S A. 2013 Nov 12;110(46):18543-8. PMID: 24128762.

" Not dangerous goods.

LKT A0248 BAM-12P 1 mg 120 Peptide, cleavage product of proenkephalin; κOR agonist. Bovine adrenal medulla 12 peptide 75513-71-2 ≥95% 1424.66 C62H97N21O16S CC(C)C(C(=O)NCC(=O)NC(CCCN=C(N)N)C(=O)N1CCCC1C(=O)NC(CCC(=O)O)C(=O)O)NC(=O)C(CCCN=C(N)N)NC(=O)C(CCCN=C(N)N)NC(=O)C(CCSC)NC(=O)C(CC2=CC=CC=C2)NC(=O)CNC(=O)CNC(=O)C(CC3=CC=C(C=C3)O)N Ambient -20°C "Davis TP, Hoyer GL, Davis P, et al. Proenkephalin A-derived peptide E and its fragments alter opioid contractility in the small intestine. Eur J Pharmacol. 1990 Dec 4;191(3):253-61. PMID: 2086244.

 

Mizuno K, Minamino N, Kangawa K, et al. A new endogenous opioid peptide from bovine adrenal medulla: isolation and amino acid sequence of a dodecapeptide (BAM-12P). Biochem Biophys Res Commun. 1980 Aug 29;95(4):1482-8. PMID: 7417331.

"

LKT A0248 BAM-12P 2 mg 204.1 Peptide, cleavage product of proenkephalin; κOR agonist. Bovine adrenal medulla 12 peptide 75513-71-2 ≥95% 1424.66 C62H97N21O16S CC(C)C(C(=O)NCC(=O)NC(CCCN=C(N)N)C(=O)N1CCCC1C(=O)NC(CCC(=O)O)C(=O)O)NC(=O)C(CCCN=C(N)N)NC(=O)C(CCCN=C(N)N)NC(=O)C(CCSC)NC(=O)C(CC2=CC=CC=C2)NC(=O)CNC(=O)CNC(=O)C(CC3=CC=C(C=C3)O)N Ambient -20°C "Davis TP, Hoyer GL, Davis P, et al. Proenkephalin A-derived peptide E and its fragments alter opioid contractility in the small intestine. Eur J Pharmacol. 1990 Dec 4;191(3):253-61. PMID: 2086244.

 

Mizuno K, Minamino N, Kangawa K, et al. A new endogenous opioid peptide from bovine adrenal medulla: isolation and amino acid sequence of a dodecapeptide (BAM-12P). Biochem Biophys Res Commun. 1980 Aug 29;95(4):1482-8. PMID: 7417331.

"

LKT A0248 BAM-12P 5 mg 359.9 Peptide, cleavage product of proenkephalin; κOR agonist. Bovine adrenal medulla 12 peptide 75513-71-2 ≥95% 1424.66 C62H97N21O16S CC(C)C(C(=O)NCC(=O)NC(CCCN=C(N)N)C(=O)N1CCCC1C(=O)NC(CCC(=O)O)C(=O)O)NC(=O)C(CCCN=C(N)N)NC(=O)C(CCCN=C(N)N)NC(=O)C(CCSC)NC(=O)C(CC2=CC=CC=C2)NC(=O)CNC(=O)CNC(=O)C(CC3=CC=C(C=C3)O)N Ambient -20°C "Davis TP, Hoyer GL, Davis P, et al. Proenkephalin A-derived peptide E and its fragments alter opioid contractility in the small intestine. Eur J Pharmacol. 1990 Dec 4;191(3):253-61. PMID: 2086244.

 

Mizuno K, Minamino N, Kangawa K, et al. A new endogenous opioid peptide from bovine adrenal medulla: isolation and amino acid sequence of a dodecapeptide (BAM-12P). Biochem Biophys Res Commun. 1980 Aug 29;95(4):1482-8. PMID: 7417331.

"

LKT A0249 BAM-22P 1 mg 276.2 Peptide, cleavage product of proenkephalin; κOR and μOR agonist. Bovine adrenal medulla 22 peptide ≥95% 2839.28 C130H184N38O31S2 CC(C)C(C(=O)NCC(=O)NC(CCCNC(=N)N)C(=O)N1CCCC1C(=O)NC(CCC(=O)O)C(=O)NC(CC2=CNC3=CC=CC=C32)C(=O)NC(CC4=CNC5=CC=CC=C54)C(=O)NC(CCSC)C(=O)NC(CC(=O)O)C(=O)NC(CC6=CC=C(C=C6)O)C(=O)NC(CCC(=O)N)C(=O)NC(CCCCN)C(=O)NC(CCCNC(=N)N)C(=O)NC(CC7=CC=C(C=C7)O)C(=O)NCC(=O)O)NC(=O)C(CCCNC(=N)N)NC(=O)C(CCCNC(=N)N)NC(=O)C(CCSC)NC(=O)C(CC8=CC=CC=C8)NC(=O)CNC(=O)CNC(=O)C(CC9=CC=C(C=C9)O)N Ambient -20°C Cai M, Chen T, Quirion R, et al. The involvement of spinal bovine adrenal medulla 22-like peptide, the proenkephalin derivative, in modulation of nociceptive processing. Eur J Neurosci. 2007 Sep;26(5):1128-38. PMID: 17767492. Not dangerous goods.

LKT A0249 BAM-22P 2 mg 468.2 Peptide, cleavage product of proenkephalin; κOR and μOR agonist. Bovine adrenal medulla 22 peptide ≥95% 2839.28 C130H184N38O31S2 CC(C)C(C(=O)NCC(=O)NC(CCCNC(=N)N)C(=O)N1CCCC1C(=O)NC(CCC(=O)O)C(=O)NC(CC2=CNC3=CC=CC=C32)C(=O)NC(CC4=CNC5=CC=CC=C54)C(=O)NC(CCSC)C(=O)NC(CC(=O)O)C(=O)NC(CC6=CC=C(C=C6)O)C(=O)NC(CCC(=O)N)C(=O)NC(CCCCN)C(=O)NC(CCCNC(=N)N)C(=O)NC(CC7=CC=C(C=C7)O)C(=O)NCC(=O)O)NC(=O)C(CCCNC(=N)N)NC(=O)C(CCCNC(=N)N)NC(=O)C(CCSC)NC(=O)C(CC8=CC=CC=C8)NC(=O)CNC(=O)CNC(=O)C(CC9=CC=C(C=C9)O)N Ambient -20°C Cai M, Chen T, Quirion R, et al. The involvement of spinal bovine adrenal medulla 22-like peptide, the proenkephalin derivative, in modulation of nociceptive processing. Eur J Neurosci. 2007 Sep;26(5):1128-38. PMID: 17767492. Not dangerous goods.

LKT A0249 BAM-22P 5 mg 828.1 Peptide, cleavage product of proenkephalin; κOR and μOR agonist. Bovine adrenal medulla 22 peptide ≥95% 2839.28 C130H184N38O31S2 CC(C)C(C(=O)NCC(=O)NC(CCCNC(=N)N)C(=O)N1CCCC1C(=O)NC(CCC(=O)O)C(=O)NC(CC2=CNC3=CC=CC=C32)C(=O)NC(CC4=CNC5=CC=CC=C54)C(=O)NC(CCSC)C(=O)NC(CC(=O)O)C(=O)NC(CC6=CC=C(C=C6)O)C(=O)NC(CCC(=O)N)C(=O)NC(CCCCN)C(=O)NC(CCCNC(=N)N)C(=O)NC(CC7=CC=C(C=C7)O)C(=O)NCC(=O)O)NC(=O)C(CCCNC(=N)N)NC(=O)C(CCCNC(=N)N)NC(=O)C(CCSC)NC(=O)C(CC8=CC=CC=C8)NC(=O)CNC(=O)CNC(=O)C(CC9=CC=C(C=C9)O)N Ambient -20°C Cai M, Chen T, Quirion R, et al. The involvement of spinal bovine adrenal medulla 22-like peptide, the proenkephalin derivative, in modulation of nociceptive processing. Eur J Neurosci. 2007 Sep;26(5):1128-38. PMID: 17767492. Not dangerous goods.

LKT A0501 Abamectin 1 g 52.6 Macrocyclic lactone avermectin; GABA antagonist, F0F1-ATPase and adenine nucleotide translocator inhibitor. Avermectin B(sub 1) Avermectin B1; 5-O-demethyl-25-de(91-methylpropyl)-25- (1-methylethyl)avermectin A1a (4:1) 71751-41-2 ≥70% C48H72O14(B1a) C47H70O14(B1b) CCC(C)C1C(C=CC2(O1)CC3CC(O2)CC=C(C(C(C=CC=C4COC5C4(C(C=C(C5O)C)C(=O)O3)O)C)OC6CC(C(C(O6)C)OC7CC(C(C(O7)C)O)OC)OC)C)C Protect from light. Ambient Ambient Soluble in methanol, acetone, isopropanol or toluene. "Castanha Zanoli JC, Maioli MA, Medeiros HC, et al. Abamectin affects the bioenergetics of liver mitochondria: A potential mechanism of hepatotoxicity. Toxicol In Vitro. 2012 Feb;26(1):51-6. PMID: 22024101.

 

Celik-Ozenci C, Tasatargil A, Tekcan M, et al. Effects of abamectin exposure on male fertility in rats: potential role of oxidative stress-mediated poly(ADP-ribose) polymerase (PARP) activation. Regul Toxicol Pharmacol. 2011 Dec;61(3):310-7. PMID: 21945325.

 

Holden-Dye L, Walker RJ. Avermectin and avermectin derivatives are antagonists at the 4-aminobutyric acid (GABA) receptor on the somatic muscle cells of Ascaris; is this the site of anthelmintic action? Parasitology. 1990 Oct;101 Pt 2:265-71. PMID: 2175874.

" N, T+ "UN number: 2811     Class:  6.1     Packing group:  I

Proper shipping name:  Toxic solids, organic, n.o.s. (Abamectin)

Reportable Quantity (RQ):     Marine pollutant:  No.     Poison inhalation hazard:  No"

LKT A0501 Abamectin 5 g 178.5 Macrocyclic lactone avermectin; GABA antagonist, F0F1-ATPase and adenine nucleotide translocator inhibitor. Avermectin B(sub 1) Avermectin B1; 5-O-demethyl-25-de(91-methylpropyl)-25- (1-methylethyl)avermectin A1a (4:1) 71751-41-2 ≥70% C48H72O14(B1a) C47H70O14(B1b) CCC(C)C1C(C=CC2(O1)CC3CC(O2)CC=C(C(C(C=CC=C4COC5C4(C(C=C(C5O)C)C(=O)O3)O)C)OC6CC(C(C(O6)C)OC7CC(C(C(O7)C)O)OC)OC)C)C Protect from light. Ambient Ambient Soluble in methanol, acetone, isopropanol or toluene. "Castanha Zanoli JC, Maioli MA, Medeiros HC, et al. Abamectin affects the bioenergetics of liver mitochondria: A potential mechanism of hepatotoxicity. Toxicol In Vitro. 2012 Feb;26(1):51-6. PMID: 22024101.

 

Celik-Ozenci C, Tasatargil A, Tekcan M, et al. Effects of abamectin exposure on male fertility in rats: potential role of oxidative stress-mediated poly(ADP-ribose) polymerase (PARP) activation. Regul Toxicol Pharmacol. 2011 Dec;61(3):310-7. PMID: 21945325.

 

Holden-Dye L, Walker RJ. Avermectin and avermectin derivatives are antagonists at the 4-aminobutyric acid (GABA) receptor on the somatic muscle cells of Ascaris; is this the site of anthelmintic action? Parasitology. 1990 Oct;101 Pt 2:265-71. PMID: 2175874.

" N, T+ "UN number: 2811     Class:  6.1     Packing group:  I

Proper shipping name:  Toxic solids, organic, n.o.s. (Abamectin)

Reportable Quantity (RQ):     Marine pollutant:  No.     Poison inhalation hazard:  No"

LKT A0501 Abamectin 25 g 682.6 Macrocyclic lactone avermectin; GABA antagonist, F0F1-ATPase and adenine nucleotide translocator inhibitor. Avermectin B(sub 1) Avermectin B1; 5-O-demethyl-25-de(91-methylpropyl)-25- (1-methylethyl)avermectin A1a (4:1) 71751-41-2 ≥70% C48H72O14(B1a) C47H70O14(B1b) CCC(C)C1C(C=CC2(O1)CC3CC(O2)CC=C(C(C(C=CC=C4COC5C4(C(C=C(C5O)C)C(=O)O3)O)C)OC6CC(C(C(O6)C)OC7CC(C(C(O7)C)O)OC)OC)C)C Protect from light. Ambient Ambient Soluble in methanol, acetone, isopropanol or toluene. "Castanha Zanoli JC, Maioli MA, Medeiros HC, et al. Abamectin affects the bioenergetics of liver mitochondria: A potential mechanism of hepatotoxicity. Toxicol In Vitro. 2012 Feb;26(1):51-6. PMID: 22024101.

 

Celik-Ozenci C, Tasatargil A, Tekcan M, et al. Effects of abamectin exposure on male fertility in rats: potential role of oxidative stress-mediated poly(ADP-ribose) polymerase (PARP) activation. Regul Toxicol Pharmacol. 2011 Dec;61(3):310-7. PMID: 21945325.

 

Holden-Dye L, Walker RJ. Avermectin and avermectin derivatives are antagonists at the 4-aminobutyric acid (GABA) receptor on the somatic muscle cells of Ascaris; is this the site of anthelmintic action? Parasitology. 1990 Oct;101 Pt 2:265-71. PMID: 2175874.

" N, T+ "UN number: 2811     Class:  6.1     Packing group:  I

Proper shipping name:  Toxic solids, organic, n.o.s. (Abamectin)

Reportable Quantity (RQ):     Marine pollutant:  No.     Poison inhalation hazard:  No"

LKT A0802 Acarbose 1 g 67.9 α-glucosidase inhibitor. "O-4,6-Dideoxy-4-[[[1S-(1α,4α,5-β,6α))-4,5,6- trihydroxy-3-(hydroxymethyl)-2-cyclohexen-1-

yl]amino]-α-D-glucopyranosyl-(1-4)-O-α-D-

glucopyranosyl-(1-4)-D-glucose" Bay g 5421; Glucobay; Prandase; Precose 56180-94-0 ≥98% 645.6 C25H43NO18 CC1C(C(C(C(O1)OC2C(OC(C(C2O)O)OC3C(OC(C(C3O)O)O)CO)CO)O)O)NC4C=C(C(C(C4O)O)O)CO Ambient Ambient Soluble in water (129mg/mL), methanol, ethanol (8mg/mL), and DMSO (129mg/mL) "Kalra S. Alpha glucosidase inhibitors. J Pak Med Assoc. 2014 Apr;64(4):474-6. PMID: 24864650.

 

Okada K, Yanagawa T, Warabi E, et al. The alpha-glucosidase inhibitor acarbose prevents obesity and simple steatosis in sequestosome 1/A170/p62 deficient mice. Hepatol Res. 2009 May;39(5):490-500. PMID: 19207582.

 

Hoffmann J, Spengler M. Efficacy of 24-week monotherapy with acarbose, metformin, or placebo in dietary-treated NIDDM patients: the Essen-II Study. Am J Med. 1997 Dec;103(6):483-90. PMID: 9428831.

" Not dangerous goods.

LKT A0802 Acarbose 5 g 271.7 α-glucosidase inhibitor. "O-4,6-Dideoxy-4-[[[1S-(1α,4α,5-β,6α))-4,5,6- trihydroxy-3-(hydroxymethyl)-2-cyclohexen-1-

yl]amino]-α-D-glucopyranosyl-(1-4)-O-α-D-

glucopyranosyl-(1-4)-D-glucose" Bay g 5421; Glucobay; Prandase; Precose 56180-94-0 ≥98% 645.6 C25H43NO18 CC1C(C(C(C(O1)OC2C(OC(C(C2O)O)OC3C(OC(C(C3O)O)O)CO)CO)O)O)NC4C=C(C(C(C4O)O)O)CO Ambient Ambient Soluble in water (129mg/mL), methanol, ethanol (8mg/mL), and DMSO (129mg/mL) "Kalra S. Alpha glucosidase inhibitors. J Pak Med Assoc. 2014 Apr;64(4):474-6. PMID: 24864650.

 

Okada K, Yanagawa T, Warabi E, et al. The alpha-glucosidase inhibitor acarbose prevents obesity and simple steatosis in sequestosome 1/A170/p62 deficient mice. Hepatol Res. 2009 May;39(5):490-500. PMID: 19207582.

 

Hoffmann J, Spengler M. Efficacy of 24-week monotherapy with acarbose, metformin, or placebo in dietary-treated NIDDM patients: the Essen-II Study. Am J Med. 1997 Dec;103(6):483-90. PMID: 9428831.

" Not dangerous goods.

LKT A0802 Acarbose 25 g 679.5 α-glucosidase inhibitor. "O-4,6-Dideoxy-4-[[[1S-(1α,4α,5-β,6α))-4,5,6- trihydroxy-3-(hydroxymethyl)-2-cyclohexen-1-

yl]amino]-α-D-glucopyranosyl-(1-4)-O-α-D-

glucopyranosyl-(1-4)-D-glucose" Bay g 5421; Glucobay; Prandase; Precose 56180-94-0 ≥98% 645.6 C25H43NO18 CC1C(C(C(C(O1)OC2C(OC(C(C2O)O)OC3C(OC(C(C3O)O)O)CO)CO)O)O)NC4C=C(C(C(C4O)O)O)CO Ambient Ambient Soluble in water (129mg/mL), methanol, ethanol (8mg/mL), and DMSO (129mg/mL) "Kalra S. Alpha glucosidase inhibitors. J Pak Med Assoc. 2014 Apr;64(4):474-6. PMID: 24864650.

 

Okada K, Yanagawa T, Warabi E, et al. The alpha-glucosidase inhibitor acarbose prevents obesity and simple steatosis in sequestosome 1/A170/p62 deficient mice. Hepatol Res. 2009 May;39(5):490-500. PMID: 19207582.

 

Hoffmann J, Spengler M. Efficacy of 24-week monotherapy with acarbose, metformin, or placebo in dietary-treated NIDDM patients: the Essen-II Study. Am J Med. 1997 Dec;103(6):483-90. PMID: 9428831.

" Not dangerous goods.

LKT A0812 Ac-D-E 5 mg 59.5 Mast cell stabilizer. Isospaglumic acid, NAAG 3106-85-2 ≥95% 304.3 C11H16N2O8 CC(=O)NC(CC(=O)O)C(=O)NC(CCC(=O)O)C(=O)O Ambient -20°C Horak F. Seasonal allergic rhinitis. Newer treatment approaches. Drugs. 1993 Apr;45(4):518-27. PMID: 7684672. Xi

LKT A0812 Ac-D-E 10 mg 101.9 Mast cell stabilizer. Isospaglumic acid, NAAG 3106-85-2 ≥95% 304.3 C11H16N2O8 CC(=O)NC(CC(=O)O)C(=O)NC(CCC(=O)O)C(=O)O Ambient -20°C Horak F. Seasonal allergic rhinitis. Newer treatment approaches. Drugs. 1993 Apr;45(4):518-27. PMID: 7684672. Xi

LKT A0812 Ac-D-E 25 mg 180.2 Mast cell stabilizer. Isospaglumic acid, NAAG 3106-85-2 ≥95% 304.3 C11H16N2O8 CC(=O)NC(CC(=O)O)C(=O)NC(CCC(=O)O)C(=O)O Ambient -20°C Horak F. Seasonal allergic rhinitis. Newer treatment approaches. Drugs. 1993 Apr;45(4):518-27. PMID: 7684672. Xi

LKT A0816 Acemetacin 1 g 33.9 Glycolic acid ester prodrug of indomethacin, NSAID; COX-1/2 inhibitor. 1-(4-Chlorobenzoyl)-5-methoxy-2-methyl-1H-indole-3-acetic acid carboxymethyl ester Acemix; Emflex; Rantudil; Solart 53164-05-9 ≥98% 415.83 C21H18ClNO6 CC1=C(C2=C(N1C(=O)C3=CC=C(C=C3)Cl)C=CC(=C2)OC)CC(=O)OCC(=O)O Ambient Ambient Soluble in DMSO. "Chávez-Piña AE, McKnight W, Dicay M, et al. Mechanisms underlying the anti-inflammatory activity and gastric safety of acemetacin. Br J Pharmacol. 2007 Nov;152(6):930-8. PMID: 17876306.

 

Fernandes E, Costa D, Toste SA, et al. In vitro scavenging activity for reactive oxygen and nitrogen species by nonsteroidal anti-inflammatory indole, pyrrole, and oxazole derivative drugs. Free Radic Biol Med. 2004 Dec 1;37(11):1895-905. PMID: 15528048.

" T+ "UN number: 2811     Class: 6.1     Packing Group: II

Proper shipping name: Toxic solid, organic, n.o.s. (Acemetacin)

Poison inhalation hazard:  No"

LKT A0816 Acemetacin 5 g 122.3 Glycolic acid ester prodrug of indomethacin, NSAID; COX-1/2 inhibitor. 1-(4-Chlorobenzoyl)-5-methoxy-2-methyl-1H-indole-3-acetic acid carboxymethyl ester Acemix; Emflex; Rantudil; Solart 53164-05-9 ≥98% 415.83 C21H18ClNO6 CC1=C(C2=C(N1C(=O)C3=CC=C(C=C3)Cl)C=CC(=C2)OC)CC(=O)OCC(=O)O Ambient Ambient Soluble in DMSO. "Chávez-Piña AE, McKnight W, Dicay M, et al. Mechanisms underlying the anti-inflammatory activity and gastric safety of acemetacin. Br J Pharmacol. 2007 Nov;152(6):930-8. PMID: 17876306.

 

Fernandes E, Costa D, Toste SA, et al. In vitro scavenging activity for reactive oxygen and nitrogen species by nonsteroidal anti-inflammatory indole, pyrrole, and oxazole derivative drugs. Free Radic Biol Med. 2004 Dec 1;37(11):1895-905. PMID: 15528048.

" T+ "UN number: 2811     Class: 6.1     Packing Group: II

Proper shipping name: Toxic solid, organic, n.o.s. (Acemetacin)

Poison inhalation hazard:  No"

LKT A0825 Ac-GPK-pNA 25 mg 1275.2 Caspase substrate. ≥95% 462.5 C21H30N6O6 Ambient -20°C

LKT A0826 Ac-GPK(Ac)-pNA 25 mg 1275.2 Caspase substrate. ≥95% 504.5 C23H32N6O7 Ambient -20°C

LKT A0832 Ac-IEAR-pNA 25 mg 1275.2 Caspase substrate. ≥95% 649.7 C28H43N9O9 Ambient -20°C

LKT A0833 Acipimox 1 g 61.1 Niacin derivative. 5-Methylpyrazinecarboxylic acid 4-oxide 51037-30-0 ≥98% 154.12 C6H6N2O3 CC1=CN=C(C=[N+]1[O-])C(=O)O Ambient Ambient Water 20 mg/mL "Møller N, Gormsen LC, Schmitz O, et al. Free fatty acids inhibit growth hormone/signal transducer and activator of transcription-5 signaling in human muscle: a potential feedback mechanism. J Clin Endocrinol Metab. 2009 Jun;94(6):2204-7. PMID: 19276230.

 

Christie AW, McCormick DK, Emmison N, et al. Mechanism of anti-lipolytic action of acipimox in isolated rat adipocytes. Diabetologia. 1996 Jan;39(1):45-53. PMID: 8720602.

" Xi Not dangerous goods.

LKT A0833 Acipimox 5 g 169.9 Niacin derivative. 5-Methylpyrazinecarboxylic acid 4-oxide 51037-30-0 ≥98% 154.12 C6H6N2O3 CC1=CN=C(C=[N+]1[O-])C(=O)O Ambient Ambient Water 20 mg/mL "Møller N, Gormsen LC, Schmitz O, et al. Free fatty acids inhibit growth hormone/signal transducer and activator of transcription-5 signaling in human muscle: a potential feedback mechanism. J Clin Endocrinol Metab. 2009 Jun;94(6):2204-7. PMID: 19276230.

 

Christie AW, McCormick DK, Emmison N, et al. Mechanism of anti-lipolytic action of acipimox in isolated rat adipocytes. Diabetologia. 1996 Jan;39(1):45-53. PMID: 8720602.

" Xi Not dangerous goods.

LKT A0833 Acipimox 10 g 237.8 Niacin derivative. 5-Methylpyrazinecarboxylic acid 4-oxide 51037-30-0 ≥98% 154.12 C6H6N2O3 CC1=CN=C(C=[N+]1[O-])C(=O)O Ambient Ambient Water 20 mg/mL "Møller N, Gormsen LC, Schmitz O, et al. Free fatty acids inhibit growth hormone/signal transducer and activator of transcription-5 signaling in human muscle: a potential feedback mechanism. J Clin Endocrinol Metab. 2009 Jun;94(6):2204-7. PMID: 19276230.

 

Christie AW, McCormick DK, Emmison N, et al. Mechanism of anti-lipolytic action of acipimox in isolated rat adipocytes. Diabetologia. 1996 Jan;39(1):45-53. PMID: 8720602.

" Xi Not dangerous goods.

LKT A0834 Ac-IETD-pNA 25 mg 1275.2 Caspase 8 substrate. ≥95% 638.6 C27H38N6O12 Ambient -20°C "Smith GK, Barrett DG, Blackburn K, et al. Expression, preparation, and high-throughput screening of caspase-8: discovery of redox-based and steroid diacid inhibition. Arch Biochem Biophys. 2002 Mar 15;399(2):195-205. PMID: 11888206.

 

Koeplinger KA, Mildner AM, Leone JW, et al. Caspase 8: an efficient method for large-scale autoactivation of recombinant procaspase 8 by matrix adsorption and characterization of the active enzyme. Protein Expr Purif. 2000 Apr;18(3):378-87. PMID: 10733893.

"

LKT A0918 N-Acetyl-L-Cysteine 10 g 30.3 Cysteine derivative, antioxidant, treats acetaminophen overdose. L-α-Acetamido-β-mercaptopropionic acid "Acetylcysteine; Brunac; Fabrol; Fluimucil; Fluprowit; Mucosil

" 616-91-1 ≥98% 163.2 C5H9NO3S CC(=O)NC(CS)C(=O)O Ambient Ambient Soluble in water. "Lim JH, Lee YM, Park SR, et al. Anticancer activity of hispidin via reactive oxygen species-mediated apoptosis in colon cancer cells. Anticancer Res. 2014 Aug;34(8):4087-93. PMID: 25075033.

 

Grosicka-Maciąg E, Szumiło M, Czeczot H, et al. Modulation of antioxidant defense system by the dithiocarbamate fungicides Maneb and Zineb in Chinese hamster V79 cells and the role of N-acetyl-L-cysteine. Food Chem Toxicol. 2013 Oct;60:130-4. PMID: 23871785.

 

Dean O, Giorlando F, Berk M. N-acetylcysteine in psychiatry: current therapeutic evidence and potential mechanisms of action. J Psychiatry Neurosci. 2011 Mar;36(2):78-86. PMID: 21118657.

 

Weiss L, Hildt E, Hofschneider PH. Anti-hepatitis B virus activity of N-acetyl-L-cysteine (NAC): new aspects of a well-established drug. Antiviral Res. 1996 Aug;32(1):43-53. PMID: 8863995.

 

Shibanuma M, Kuroki T, Nose K. Inhibition by N-acetyl-L-cysteine of interleukin-6 mRNA induction and activation of NF kappa B by tumor necrosis factor alpha in a mouse fibroblastic cell line, Balb/3T3. FEBS Lett. 1994 Oct 10;353(1):62-6. PMID: 7926024.

" Xi Not dangerous goods.

LKT A0918 N-Acetyl-L-Cysteine 25 g 54.6 Cysteine derivative, antioxidant, treats acetaminophen overdose. L-α-Acetamido-β-mercaptopropionic acid "Acetylcysteine; Brunac; Fabrol; Fluimucil; Fluprowit; Mucosil

" 616-91-1 ≥98% 163.2 C5H9NO3S CC(=O)NC(CS)C(=O)O Ambient Ambient Soluble in water. "Lim JH, Lee YM, Park SR, et al. Anticancer activity of hispidin via reactive oxygen species-mediated apoptosis in colon cancer cells. Anticancer Res. 2014 Aug;34(8):4087-93. PMID: 25075033.

 

Grosicka-Maciąg E, Szumiło M, Czeczot H, et al. Modulation of antioxidant defense system by the dithiocarbamate fungicides Maneb and Zineb in Chinese hamster V79 cells and the role of N-acetyl-L-cysteine. Food Chem Toxicol. 2013 Oct;60:130-4. PMID: 23871785.

 

Dean O, Giorlando F, Berk M. N-acetylcysteine in psychiatry: current therapeutic evidence and potential mechanisms of action. J Psychiatry Neurosci. 2011 Mar;36(2):78-86. PMID: 21118657.

 

Weiss L, Hildt E, Hofschneider PH. Anti-hepatitis B virus activity of N-acetyl-L-cysteine (NAC): new aspects of a well-established drug. Antiviral Res. 1996 Aug;32(1):43-53. PMID: 8863995.

 

Shibanuma M, Kuroki T, Nose K. Inhibition by N-acetyl-L-cysteine of interleukin-6 mRNA induction and activation of NF kappa B by tumor necrosis factor alpha in a mouse fibroblastic cell line, Balb/3T3. FEBS Lett. 1994 Oct 10;353(1):62-6. PMID: 7926024.

" Xi Not dangerous goods.

LKT A0919 Acetyl-L-Carnitine 1 g 45 Natural carnitine derivative, involved in energy homeostasis. ALCAR; Acetylcarnitine 3040-38-8 ≥98% 203.24 C9H17NO4 CC(=O)OC(CC(=O)[O-])C[N+](C)(C)C Ambient Ambient Soluble in water, ethanol (20 mg/ml), DMF (20 mg/ml), and DMSO (10 mg/ml) "Cuccurazzu B, Bortolotto V, Valente MM, et al. Upregulation of mGlu2 receptors via NF-κB p65 acetylation is involved in the Proneurogenic and antidepressant effects of acetyl-l-carnitine. Neuropsychopharmacology. 2013 Oct;38(11):2220-30. PMID: 23670591.

 

Onofrj M, Ciccocioppo F, Varanese S, et al. Acetyl-L-carnitine: from a biological curiosity to a drug for the peripheral nervous system and beyond. Expert Rev Neurother. 2013 Aug;13(8):925-36. PMID: 23965166.

 

Virmani A, Koverech A, Ali SF, et al. Acetyl-L-Carnitine Modulates TP53 and IL10 Gene Expression Induced by 3-NPA Evoked Toxicity in PC12 Cells. Curr Neuropharmacol. 2011 Mar;9(1):195-9. PMID: 21886589.

 

Vivoli E, Di Cesare Mannelli L, Salvicchi A, et al. Acetyl-L-carnitine increases artemin level and prevents neurotrophic factor alterations during neuropathy. Neuroscience. 2010 Jun 2;167(4):1168-74. PMID: 20302919.

 

Epis R, Marcello E, Gardoni F, et al. Modulatory effect of acetyl-L-carnitine on amyloid precursor protein metabolism in hippocampal neurons. Eur J Pharmacol. 2008 Nov 12;597(1-3):51-6. PMID: 18801359.

 

Ghelardini C, Galeotti N, Calvani M, et al. Acetyl-l-carnitine induces muscarinic antinocieption in mice and rats. Neuropharmacology. 2002 Dec;43(7):1180-7. PMID: 12504925.

" Not dangerous goods.

LKT A0919 Acetyl-L-Carnitine 5 g 121.9 Natural carnitine derivative, involved in energy homeostasis. ALCAR; Acetylcarnitine 3040-38-8 ≥98% 203.24 C9H17NO4 CC(=O)OC(CC(=O)[O-])C[N+](C)(C)C Ambient Ambient Soluble in water, ethanol (20 mg/ml), DMF (20 mg/ml), and DMSO (10 mg/ml) "Cuccurazzu B, Bortolotto V, Valente MM, et al. Upregulation of mGlu2 receptors via NF-κB p65 acetylation is involved in the Proneurogenic and antidepressant effects of acetyl-l-carnitine. Neuropsychopharmacology. 2013 Oct;38(11):2220-30. PMID: 23670591.

 

Onofrj M, Ciccocioppo F, Varanese S, et al. Acetyl-L-carnitine: from a biological curiosity to a drug for the peripheral nervous system and beyond. Expert Rev Neurother. 2013 Aug;13(8):925-36. PMID: 23965166.

 

Virmani A, Koverech A, Ali SF, et al. Acetyl-L-Carnitine Modulates TP53 and IL10 Gene Expression Induced by 3-NPA Evoked Toxicity in PC12 Cells. Curr Neuropharmacol. 2011 Mar;9(1):195-9. PMID: 21886589.

 

Vivoli E, Di Cesare Mannelli L, Salvicchi A, et al. Acetyl-L-carnitine increases artemin level and prevents neurotrophic factor alterations during neuropathy. Neuroscience. 2010 Jun 2;167(4):1168-74. PMID: 20302919.

 

Epis R, Marcello E, Gardoni F, et al. Modulatory effect of acetyl-L-carnitine on amyloid precursor protein metabolism in hippocampal neurons. Eur J Pharmacol. 2008 Nov 12;597(1-3):51-6. PMID: 18801359.

 

Ghelardini C, Galeotti N, Calvani M, et al. Acetyl-l-carnitine induces muscarinic antinocieption in mice and rats. Neuropharmacology. 2002 Dec;43(7):1180-7. PMID: 12504925.

" Not dangerous goods.

LKT A0920 N-Acetyl-S-(N′-phenethylthiocarbamoyl)-L-cysteine 25 mg 125.9 N-acetyl cysteine conjugate of phenethylisothiocyanate. Phenethyl isothiocyanate N-acetyl-L-cysteine conjugate; PEITC N-acetyl-L-cysteine conjugate PEITC-NAC ≥95% 326.43 C14H18N2O3S2 CC(=O)NC(CSC(=S)NCCC1=CC=CC=C1)C(=O)O Ambient -20°C "Kassie F, Melkamu T, Endalew A, et al. Inhibition of lung carcinogenesis and critical cancer-related signaling pathways by N-acetyl-S-(N-2-phenethylthiocarbamoyl)-l-cysteine, indole-3-carbinol and myo-inositol, alone and in combination. Carcinogenesis. 2010 Sep;31(9):1634-41. PMID: 20603442.

 

Yang YM, Conaway CC, Chiao JW, et al. Inhibition of benzo(a)pyrene-induced lung tumorigenesis in A/J mice by dietary N-acetylcysteine conjugates of benzyl and phenethyl isothiocyanates during the postinitiation phase is associated with activation of mitogen-activated protein kinases and p53 activity and induction of apoptosis. Cancer Res. 2002 Jan 1;62(1):2-7. PMID: 11782348.

 

Chiao JW, Chung F, Krzeminski J, et al. Modulation of growth of human prostate cancer cells by the N-acetylcysteine conjugate of phenethyl isothiocyanate. Int J Oncol. 2000 Jun;16(6):1215-9. PMID: 10811998.

" Not dangerous goods.

LKT A0920 N-Acetyl-S-(N′-phenethylthiocarbamoyl)-L-cysteine 100 mg 378.1 N-acetyl cysteine conjugate of phenethylisothiocyanate. Phenethyl isothiocyanate N-acetyl-L-cysteine conjugate; PEITC N-acetyl-L-cysteine conjugate PEITC-NAC ≥95% 326.43 C14H18N2O3S2 CC(=O)NC(CSC(=S)NCCC1=CC=CC=C1)C(=O)O Ambient -20°C "Kassie F, Melkamu T, Endalew A, et al. Inhibition of lung carcinogenesis and critical cancer-related signaling pathways by N-acetyl-S-(N-2-phenethylthiocarbamoyl)-l-cysteine, indole-3-carbinol and myo-inositol, alone and in combination. Carcinogenesis. 2010 Sep;31(9):1634-41. PMID: 20603442.

 

Yang YM, Conaway CC, Chiao JW, et al. Inhibition of benzo(a)pyrene-induced lung tumorigenesis in A/J mice by dietary N-acetylcysteine conjugates of benzyl and phenethyl isothiocyanates during the postinitiation phase is associated with activation of mitogen-activated protein kinases and p53 activity and induction of apoptosis. Cancer Res. 2002 Jan 1;62(1):2-7. PMID: 11782348.

 

Chiao JW, Chung F, Krzeminski J, et al. Modulation of growth of human prostate cancer cells by the N-acetylcysteine conjugate of phenethyl isothiocyanate. Int J Oncol. 2000 Jun;16(6):1215-9. PMID: 10811998.

" Not dangerous goods.

LKT A0920 N-Acetyl-S-(N′-phenethylthiocarbamoyl)-L-cysteine 500 mg 1310.4 N-acetyl cysteine conjugate of phenethylisothiocyanate. Phenethyl isothiocyanate N-acetyl-L-cysteine conjugate; PEITC N-acetyl-L-cysteine conjugate PEITC-NAC ≥95% 326.43 C14H18N2O3S2 CC(=O)NC(CSC(=S)NCCC1=CC=CC=C1)C(=O)O Ambient -20°C "Kassie F, Melkamu T, Endalew A, et al. Inhibition of lung carcinogenesis and critical cancer-related signaling pathways by N-acetyl-S-(N-2-phenethylthiocarbamoyl)-l-cysteine, indole-3-carbinol and myo-inositol, alone and in combination. Carcinogenesis. 2010 Sep;31(9):1634-41. PMID: 20603442.

 

Yang YM, Conaway CC, Chiao JW, et al. Inhibition of benzo(a)pyrene-induced lung tumorigenesis in A/J mice by dietary N-acetylcysteine conjugates of benzyl and phenethyl isothiocyanates during the postinitiation phase is associated with activation of mitogen-activated protein kinases and p53 activity and induction of apoptosis. Cancer Res. 2002 Jan 1;62(1):2-7. PMID: 11782348.

 

Chiao JW, Chung F, Krzeminski J, et al. Modulation of growth of human prostate cancer cells by the N-acetylcysteine conjugate of phenethyl isothiocyanate. Int J Oncol. 2000 Jun;16(6):1215-9. PMID: 10811998.

" Not dangerous goods.

LKT A0921 N-Acetyl-D-Leucine 1 g 83.2 D-amino acid, incorporated into bacterial cell walls. 19764-30-8 ≥98% 173.21 C8H15NO3 CC(C)CC(C(=O)O)NC(=O)C Ambient Ambient "Leiman SA, May JM, Lebar MD, et al. D-amino acids indirectly inhibit biofilm formation in Bacillus subtilis by interfering with protein synthesis. J Bacteriol. 2013 Dec;195(23):5391-5. PMID: 24097941.

 

Kolodkin-Gal I, Romero D, Cao S, et al. D-amino acids trigger biofilm disassembly. Science. 2010 Apr 30;328(5978):627-9. PMID: 20431016.

 

Cummings JA, Fedorov AA, Xu C, et al. Annotating enzymes of uncertain function: the deacylation of D-amino acids by members of the amidohydrolase superfamily. Biochemistry. 2009 Jul 14;48(27):6469-81. PMID: 19518059.

" None Not dangerous goods.

LKT A0921 N-Acetyl-D-Leucine 5 g 279.1 D-amino acid, incorporated into bacterial cell walls. 19764-30-8 ≥98% 173.21 C8H15NO3 CC(C)CC(C(=O)O)NC(=O)C Ambient Ambient "Leiman SA, May JM, Lebar MD, et al. D-amino acids indirectly inhibit biofilm formation in Bacillus subtilis by interfering with protein synthesis. J Bacteriol. 2013 Dec;195(23):5391-5. PMID: 24097941.

 

Kolodkin-Gal I, Romero D, Cao S, et al. D-amino acids trigger biofilm disassembly. Science. 2010 Apr 30;328(5978):627-9. PMID: 20431016.

 

Cummings JA, Fedorov AA, Xu C, et al. Annotating enzymes of uncertain function: the deacylation of D-amino acids by members of the amidohydrolase superfamily. Biochemistry. 2009 Jul 14;48(27):6469-81. PMID: 19518059.

" None Not dangerous goods.

LKT A0934 Acivicin 10 mg 225 Glutamine analog, fermentation product of Streptomyces; γ-glutamyl transferase, CTP synthetase, GMP synthetase, FGAM synthetase inhibitor. (2S)-2-amino-2-[(5S)-3-chloro-4,5-dihydro-1,2-oxazol-5-yl]acetic acid α-Amino-3-chloro-4,5-dihydro-5-isoxazoleacetic acid; ACIA 42228-92-2 ≥98% 178.57 C5H7ClN2O3 C1C(ON=C1Cl)C(C(=O)O)N Ambient -20°C Soluble in water to 18mg/mL. Slightly soluble in methanol, ethanol or chloroform. "Maeda K, Nakajima Y, Motoyama T, et al. Effects of acivicin on growth, mycotoxin production and virulence of phytopathogenic fungi. Lett Appl Microbiol. 2014 May 27. [Epub ahead of print]. PMID: 24863673.

 

Hidalgo M, Rodriguez G, Kuhn JG, et al. A Phase I and pharmacological study of the glutamine antagonist acivicin with the amino acid solution aminosyn in patients with advanced solid malignancies. Clin Cancer Res. 1998 Nov;4(11):2763-70. PMID: 9829740.

 

Lyons SD, Sant ME, Christopherson RI. Cytotoxic mechanisms of glutamine antagonists in mouse L1210 leukemia. J Biol Chem. 1990 Jul 5;265(19):11377-81. PMID: 2358467.

 

Allen L, Meck R, Yunis A. The inhibition of gamma-glutamyl transpeptidase from human pancreatic carcinoma cells by (alpha S,5S)-alpha-amino-3-chloro-4,5-dihydro-5-isoxazoleacetic acid (AT-125; NSC-163501). Res Commun Chem Pathol Pharmacol. 1980 Jan;27(1):175-82. PMID: 6102405.

" Not dangerous goods.

LKT A0934 Acivicin 25 mg 506.3 Glutamine analog, fermentation product of Streptomyces; γ-glutamyl transferase, CTP synthetase, GMP synthetase, FGAM synthetase inhibitor. (2S)-2-amino-2-[(5S)-3-chloro-4,5-dihydro-1,2-oxazol-5-yl]acetic acid α-Amino-3-chloro-4,5-dihydro-5-isoxazoleacetic acid; ACIA 42228-92-2 ≥98% 178.57 C5H7ClN2O3 C1C(ON=C1Cl)C(C(=O)O)N Ambient -20°C Soluble in water to 18mg/mL. Slightly soluble in methanol, ethanol or chloroform. "Maeda K, Nakajima Y, Motoyama T, et al. Effects of acivicin on growth, mycotoxin production and virulence of phytopathogenic fungi. Lett Appl Microbiol. 2014 May 27. [Epub ahead of print]. PMID: 24863673.

 

Hidalgo M, Rodriguez G, Kuhn JG, et al. A Phase I and pharmacological study of the glutamine antagonist acivicin with the amino acid solution aminosyn in patients with advanced solid malignancies. Clin Cancer Res. 1998 Nov;4(11):2763-70. PMID: 9829740.

 

Lyons SD, Sant ME, Christopherson RI. Cytotoxic mechanisms of glutamine antagonists in mouse L1210 leukemia. J Biol Chem. 1990 Jul 5;265(19):11377-81. PMID: 2358467.

 

Allen L, Meck R, Yunis A. The inhibition of gamma-glutamyl transpeptidase from human pancreatic carcinoma cells by (alpha S,5S)-alpha-amino-3-chloro-4,5-dihydro-5-isoxazoleacetic acid (AT-125; NSC-163501). Res Commun Chem Pathol Pharmacol. 1980 Jan;27(1):175-82. PMID: 6102405.

" Not dangerous goods.

LKT A0934 Acivicin 100 mg 1612.7 Glutamine analog, fermentation product of Streptomyces; γ-glutamyl transferase, CTP synthetase, GMP synthetase, FGAM synthetase inhibitor. (2S)-2-amino-2-[(5S)-3-chloro-4,5-dihydro-1,2-oxazol-5-yl]acetic acid α-Amino-3-chloro-4,5-dihydro-5-isoxazoleacetic acid; ACIA 42228-92-2 ≥98% 178.57 C5H7ClN2O3 C1C(ON=C1Cl)C(C(=O)O)N Ambient -20°C Soluble in water to 18mg/mL. Slightly soluble in methanol, ethanol or chloroform. "Maeda K, Nakajima Y, Motoyama T, et al. Effects of acivicin on growth, mycotoxin production and virulence of phytopathogenic fungi. Lett Appl Microbiol. 2014 May 27. [Epub ahead of print]. PMID: 24863673.

 

Hidalgo M, Rodriguez G, Kuhn JG, et al. A Phase I and pharmacological study of the glutamine antagonist acivicin with the amino acid solution aminosyn in patients with advanced solid malignancies. Clin Cancer Res. 1998 Nov;4(11):2763-70. PMID: 9829740.

 

Lyons SD, Sant ME, Christopherson RI. Cytotoxic mechanisms of glutamine antagonists in mouse L1210 leukemia. J Biol Chem. 1990 Jul 5;265(19):11377-81. PMID: 2358467.

 

Allen L, Meck R, Yunis A. The inhibition of gamma-glutamyl transpeptidase from human pancreatic carcinoma cells by (alpha S,5S)-alpha-amino-3-chloro-4,5-dihydro-5-isoxazoleacetic acid (AT-125; NSC-163501). Res Commun Chem Pathol Pharmacol. 1980 Jan;27(1):175-82. PMID: 6102405.

" Not dangerous goods.

LKT A0958 Aconitine 10 mg 51.1 Toxin found in Aconitum; voltage-gated Na+ channel modulator. (1α,3α,6α,14α,15α,16β)-20-Ethyl-1,6,16-trimethoxy- 4-(methoxymethyl)aconitane-3,8,13,14,15-pentol 8-acetate 14-benzoate 20-ethyl-3alpha,13,15alpha-trihydroxy-1alpha,6alpha,16beta-trimethoxy-4-(methoxymethyl)aconitane-8,14alpha-diyl 8-acetate 14-benzoate: Acetylbenzoylaconine 302-27-2 ≥88% 645.74 C34H47NO11 CCN1CC2(C(CC(C34C2C(C(C31)C5(C6C4CC(C6OC(=O)C7=CC=CC=C7)(C(C5O)OC)O)OC(=O)C)OC)OC)O)COC Poisonous Ambient 4°C Soluble in water (0.3mg/mL)  or ethanol (35mg/mL). "Chan TY. Aconite poisoning. Clin Toxicol (Phila). 2009 Apr;47(4):279-85. PMID: 19514874.

 

Gutser UT, Friese J, Heubach JF, et al. Mode of antinociceptive and toxic action of alkaloids of Aconitum spec. Naunyn Schmiedebergs Arch Pharmacol. 1998 Jan;357(1):39-48. PMID: 9459571.

 

Okazaki M, Kimura I, Kimura M. Aconitine-induced increase and decrease of acetylcholine release in the mouse phrenic nerve-hemidiaphragm muscle preparation. Jpn J Pharmacol. 1994 Dec;66(4):421-6. PMID: 7723217.

" T+ "UN number: 1544     Class:  6.1     Packing group:  I

Proper shipping name:  Alkaloids, solid, n.o.s. (Aconitine)

Marine pollutant:  No     Poison inhalation hazard:  No"

LKT A0958 Aconitine 25 mg 89.3 Toxin found in Aconitum; voltage-gated Na+ channel modulator. (1α,3α,6α,14α,15α,16β)-20-Ethyl-1,6,16-trimethoxy- 4-(methoxymethyl)aconitane-3,8,13,14,15-pentol 8-acetate 14-benzoate 20-ethyl-3alpha,13,15alpha-trihydroxy-1alpha,6alpha,16beta-trimethoxy-4-(methoxymethyl)aconitane-8,14alpha-diyl 8-acetate 14-benzoate: Acetylbenzoylaconine 302-27-2 ≥88% 645.74 C34H47NO11 CCN1CC2(C(CC(C34C2C(C(C31)C5(C6C4CC(C6OC(=O)C7=CC=CC=C7)(C(C5O)OC)O)OC(=O)C)OC)OC)O)COC Poisonous Ambient 4°C Soluble in water (0.3mg/mL)  or ethanol (35mg/mL). "Chan TY. Aconite poisoning. Clin Toxicol (Phila). 2009 Apr;47(4):279-85. PMID: 19514874.

 

Gutser UT, Friese J, Heubach JF, et al. Mode of antinociceptive and toxic action of alkaloids of Aconitum spec. Naunyn Schmiedebergs Arch Pharmacol. 1998 Jan;357(1):39-48. PMID: 9459571.

 

Okazaki M, Kimura I, Kimura M. Aconitine-induced increase and decrease of acetylcholine release in the mouse phrenic nerve-hemidiaphragm muscle preparation. Jpn J Pharmacol. 1994 Dec;66(4):421-6. PMID: 7723217.

" T+ "UN number: 1544     Class:  6.1     Packing group:  I

Proper shipping name:  Alkaloids, solid, n.o.s. (Aconitine)

Marine pollutant:  No     Poison inhalation hazard:  No"

LKT A0958 Aconitine 100 mg 279.5 Toxin found in Aconitum; voltage-gated Na+ channel modulator. (1α,3α,6α,14α,15α,16β)-20-Ethyl-1,6,16-trimethoxy- 4-(methoxymethyl)aconitane-3,8,13,14,15-pentol 8-acetate 14-benzoate 20-ethyl-3alpha,13,15alpha-trihydroxy-1alpha,6alpha,16beta-trimethoxy-4-(methoxymethyl)aconitane-8,14alpha-diyl 8-acetate 14-benzoate: Acetylbenzoylaconine 302-27-2 ≥88% 645.74 C34H47NO11 CCN1CC2(C(CC(C34C2C(C(C31)C5(C6C4CC(C6OC(=O)C7=CC=CC=C7)(C(C5O)OC)O)OC(=O)C)OC)OC)O)COC Poisonous Ambient 4°C Soluble in water (0.3mg/mL)  or ethanol (35mg/mL). "Chan TY. Aconite poisoning. Clin Toxicol (Phila). 2009 Apr;47(4):279-85. PMID: 19514874.

 

Gutser UT, Friese J, Heubach JF, et al. Mode of antinociceptive and toxic action of alkaloids of Aconitum spec. Naunyn Schmiedebergs Arch Pharmacol. 1998 Jan;357(1):39-48. PMID: 9459571.

 

Okazaki M, Kimura I, Kimura M. Aconitine-induced increase and decrease of acetylcholine release in the mouse phrenic nerve-hemidiaphragm muscle preparation. Jpn J Pharmacol. 1994 Dec;66(4):421-6. PMID: 7723217.

" T+ "UN number: 1544     Class:  6.1     Packing group:  I

Proper shipping name:  Alkaloids, solid, n.o.s. (Aconitine)

Marine pollutant:  No     Poison inhalation hazard:  No"

LKT A0960 Adrenocorticotropic Hormone (1-39), human 1 mg 1275.2 Endogenous peptide hormone, involved in stress signaling; MC2 agonist. ACTH 12279-41-3 ≥95% 4541.1 C207H308N56O58S "CC(C)CC(C(=O)NC(CCC(=O)O)C(=O)NC(Cc1ccccc1)C(=O)O)NC(=O)C2CCCN2C(=O)C(Cc3ccccc3)NC(=O)C(C)NC(=O)C(CCC(=O)O)NC(=O)C(C)NC(=O)C(CO)NC(=O)C(CCC(=O)O)NC(=O)C(CC(=O)O)NC(=O)C(CCC(=O)O)NC(=O)C(C)NC(=O)CNC(=O)C(CC(=O)N)NC(=O)C4CCCN4C(=O)C(Cc5ccc(cc5)O)NC(=O)C(C(C)C)NC(=O)C(CCCCN)NC(=O)C(C(C)C)NC(=O)C6CCCN6C(=O)C(CCCNC(=N)N)NC(=O)C(CCCNC(=N)N)NC(=O)C(CCCCN)NC(=O)C(CCCCN)NC(=O)CNC(=O)C(C(C)C)NC(=O)C7CCCN7C(=O)C(CCCCN)NC(=O)CNC(=O)C(Cc8c[nH]c9c8cccc9)NC(=O)C(CCCNC(=N)N)NC(=O)C(Cc1ccccc1)NC(=O)C(Cc1c[nH]cn1)NC(=O)C(CCC(=O)O)NC(=O)C(CCSC)NC(=O)C(CO)NC(=O)C(Cc1ccc(cc1)O)NC(=O)C(CO)N

" Ambient -20°C "Berkovich R, Agius MA. Mechanisms of action of ACTH in the management of relapsing forms of multiple sclerosis. Ther Adv Neurol Disord. 2014 Mar;7(2):83-96. PMID: 24587825.

 

Isales CM, Zaidi M, Blair HC. ACTH is a novel regulator of bone mass. Ann N Y Acad Sci. 2010 Mar;1192:110-6. PMID: 20392225.

" Xi Not dangerous goods.

LKT A0961 Adrenocorticotropic Hormone (1-39), rat 0.5 mg 228 Endogenous peptide hormone, involved in stress signaling; MC2 agonist. ACTH 77465-10-2 ≥95% 4582.3 C210H315N57O57S Ambient -20°C "Berkovich R, Agius MA. Mechanisms of action of ACTH in the management of relapsing forms of multiple sclerosis. Ther Adv Neurol Disord. 2014 Mar;7(2):83-96. PMID: 24587825.

 

Isales CM, Zaidi M, Blair HC. ACTH is a novel regulator of bone mass. Ann N Y Acad Sci. 2010 Mar;1192:110-6. PMID: 20392225.

" Not dangerous goods.

LKT A0961 Adrenocorticotropic Hormone (1-39), rat 1 mg 387 Endogenous peptide hormone, involved in stress signaling; MC2 agonist. ACTH 77465-10-2 ≥95% 4582.3 C210H315N57O57S Ambient -20°C "Berkovich R, Agius MA. Mechanisms of action of ACTH in the management of relapsing forms of multiple sclerosis. Ther Adv Neurol Disord. 2014 Mar;7(2):83-96. PMID: 24587825.

 

Isales CM, Zaidi M, Blair HC. ACTH is a novel regulator of bone mass. Ann N Y Acad Sci. 2010 Mar;1192:110-6. PMID: 20392225.

" Not dangerous goods.

LKT A0961 Adrenocorticotropic Hormone (1-39), rat 2.5 mg 684.1 Endogenous peptide hormone, involved in stress signaling; MC2 agonist. ACTH 77465-10-2 ≥95% 4582.3 C210H315N57O57S Ambient -20°C "Berkovich R, Agius MA. Mechanisms of action of ACTH in the management of relapsing forms of multiple sclerosis. Ther Adv Neurol Disord. 2014 Mar;7(2):83-96. PMID: 24587825.

 

Isales CM, Zaidi M, Blair HC. ACTH is a novel regulator of bone mass. Ann N Y Acad Sci. 2010 Mar;1192:110-6. PMID: 20392225.

" Not dangerous goods.

LKT A0962 Adrenocorticotropic Hormone (1-4) 1 mg 36 Endogenous peptide hormone fragment, involved in stress signaling; MC2 agonist. ACTH ≥95% 486.6 C20H30N4O8S CSCCC(C(=O)O)NC(=O)C(CO)NC(=O)C(C(C1=CC=C(C=C1)O)C(=O)C(CO)N)N Ambient -20°C "Berkovich R, Agius MA. Mechanisms of action of ACTH in the management of relapsing forms of multiple sclerosis. Ther Adv Neurol Disord. 2014 Mar;7(2):83-96. PMID: 24587825.

 

Isales CM, Zaidi M, Blair HC. ACTH is a novel regulator of bone mass. Ann N Y Acad Sci. 2010 Mar;1192:110-6. PMID: 20392225.

" Not dangerous goods.

LKT A0962 Adrenocorticotropic Hormone (1-4) 2 mg 60 Endogenous peptide hormone fragment, involved in stress signaling; MC2 agonist. ACTH ≥95% 486.6 C20H30N4O8S CSCCC(C(=O)O)NC(=O)C(CO)NC(=O)C(C(C1=CC=C(C=C1)O)C(=O)C(CO)N)N Ambient -20°C "Berkovich R, Agius MA. Mechanisms of action of ACTH in the management of relapsing forms of multiple sclerosis. Ther Adv Neurol Disord. 2014 Mar;7(2):83-96. PMID: 24587825.

 

Isales CM, Zaidi M, Blair HC. ACTH is a novel regulator of bone mass. Ann N Y Acad Sci. 2010 Mar;1192:110-6. PMID: 20392225.

" Not dangerous goods.

LKT A0962 Adrenocorticotropic Hormone (1-4) 5 mg 107.8 Endogenous peptide hormone fragment, involved in stress signaling; MC2 agonist. ACTH ≥95% 486.6 C20H30N4O8S CSCCC(C(=O)O)NC(=O)C(CO)NC(=O)C(C(C1=CC=C(C=C1)O)C(=O)C(CO)N)N Ambient -20°C "Berkovich R, Agius MA. Mechanisms of action of ACTH in the management of relapsing forms of multiple sclerosis. Ther Adv Neurol Disord. 2014 Mar;7(2):83-96. PMID: 24587825.

 

Isales CM, Zaidi M, Blair HC. ACTH is a novel regulator of bone mass. Ann N Y Acad Sci. 2010 Mar;1192:110-6. PMID: 20392225.

" Not dangerous goods.

LKT A0963 Adrenocorticotropic Hormone (1-10), human 1 mg 48 Endogenous peptide hormone fragment, involved in stress signaling; MC2 agonist. ACTH ≥95% 1299.4 C59H78N16O16S1 CSCCC(C(=O)NC(CCC(=O)O)C(=O)NC(CC1C=NC=N1)C(=O)NC(CC2=CC=CC=C2)C(=O)NC(CCCN=C(N)N)C(=O)NC(CC3=CNC4=CC=CC=C43)C(=O)NCC(=O)O)NC(=O)C(CO)NC(=O)C(CC5=CC=C(C=C5)O)NC(=O)C(CO)N Ambient -20°C "Berkovich R, Agius MA. Mechanisms of action of ACTH in the management of relapsing forms of multiple sclerosis. Ther Adv Neurol Disord. 2014 Mar;7(2):83-96. PMID: 24587825.

 

Isales CM, Zaidi M, Blair HC. ACTH is a novel regulator of bone mass. Ann N Y Acad Sci. 2010 Mar;1192:110-6. PMID: 20392225.

" Not dangerous goods.

LKT A0963 Adrenocorticotropic Hormone (1-10), human 2 mg 81 Endogenous peptide hormone fragment, involved in stress signaling; MC2 agonist. ACTH ≥95% 1299.4 C59H78N16O16S1 CSCCC(C(=O)NC(CCC(=O)O)C(=O)NC(CC1C=NC=N1)C(=O)NC(CC2=CC=CC=C2)C(=O)NC(CCCN=C(N)N)C(=O)NC(CC3=CNC4=CC=CC=C43)C(=O)NCC(=O)O)NC(=O)C(CO)NC(=O)C(CC5=CC=C(C=C5)O)NC(=O)C(CO)N Ambient -20°C "Berkovich R, Agius MA. Mechanisms of action of ACTH in the management of relapsing forms of multiple sclerosis. Ther Adv Neurol Disord. 2014 Mar;7(2):83-96. PMID: 24587825.

 

Isales CM, Zaidi M, Blair HC. ACTH is a novel regulator of bone mass. Ann N Y Acad Sci. 2010 Mar;1192:110-6. PMID: 20392225.

" Not dangerous goods.

LKT A0963 Adrenocorticotropic Hormone (1-10), human 5 mg 144 Endogenous peptide hormone fragment, involved in stress signaling; MC2 agonist. ACTH ≥95% 1299.4 C59H78N16O16S1 CSCCC(C(=O)NC(CCC(=O)O)C(=O)NC(CC1C=NC=N1)C(=O)NC(CC2=CC=CC=C2)C(=O)NC(CCCN=C(N)N)C(=O)NC(CC3=CNC4=CC=CC=C43)C(=O)NCC(=O)O)NC(=O)C(CO)NC(=O)C(CC5=CC=C(C=C5)O)NC(=O)C(CO)N Ambient -20°C "Berkovich R, Agius MA. Mechanisms of action of ACTH in the management of relapsing forms of multiple sclerosis. Ther Adv Neurol Disord. 2014 Mar;7(2):83-96. PMID: 24587825.

 

Isales CM, Zaidi M, Blair HC. ACTH is a novel regulator of bone mass. Ann N Y Acad Sci. 2010 Mar;1192:110-6. PMID: 20392225.

" Not dangerous goods.

LKT A0964 Adrenocorticotropic Hormone (1-13), human 0.5 mg 72.1 Endogenous peptide hormone fragment, involved in stress signaling; MC2 agonist. ACTH ≥95% 1623.9 C75H106N20O19S1 CC(C)C(C(=O)O)NC(=O)C1CCCN1C(=O)C(CCCCN)NC(=O)CNC(=O)C(CC2=CNC3=CC=CC=C32)NC(=O)C(CCCNC(=N)N)NC(=O)C(CC4=CC=CC=C4)NC(=O)C(CC5=CN=CN5)NC(=O)C(CCC(=O)O)NC(=O)C(CCSC)NC(=O)C(CO)NC(=O)C(CC6=CC=C(C=C6)O)NC(=O)C(CO)N Ambient -20°C "Berkovich R, Agius MA. Mechanisms of action of ACTH in the management of relapsing forms of multiple sclerosis. Ther Adv Neurol Disord. 2014 Mar;7(2):83-96. PMID: 24587825.

 

Isales CM, Zaidi M, Blair HC. ACTH is a novel regulator of bone mass. Ann N Y Acad Sci. 2010 Mar;1192:110-6. PMID: 20392225.

"

LKT A0964 Adrenocorticotropic Hormone (1-13), human 1 mg 123.1 Endogenous peptide hormone fragment, involved in stress signaling; MC2 agonist. ACTH ≥95% 1623.9 C75H106N20O19S1 CC(C)C(C(=O)O)NC(=O)C1CCCN1C(=O)C(CCCCN)NC(=O)CNC(=O)C(CC2=CNC3=CC=CC=C32)NC(=O)C(CCCNC(=N)N)NC(=O)C(CC4=CC=CC=C4)NC(=O)C(CC5=CN=CN5)NC(=O)C(CCC(=O)O)NC(=O)C(CCSC)NC(=O)C(CO)NC(=O)C(CC6=CC=C(C=C6)O)NC(=O)C(CO)N Ambient -20°C "Berkovich R, Agius MA. Mechanisms of action of ACTH in the management of relapsing forms of multiple sclerosis. Ther Adv Neurol Disord. 2014 Mar;7(2):83-96. PMID: 24587825.

 

Isales CM, Zaidi M, Blair HC. ACTH is a novel regulator of bone mass. Ann N Y Acad Sci. 2010 Mar;1192:110-6. PMID: 20392225.

"

LKT A0964 Adrenocorticotropic Hormone (1-13), human 2.5 mg 216.1 Endogenous peptide hormone fragment, involved in stress signaling; MC2 agonist. ACTH ≥95% 1623.9 C75H106N20O19S1 CC(C)C(C(=O)O)NC(=O)C1CCCN1C(=O)C(CCCCN)NC(=O)CNC(=O)C(CC2=CNC3=CC=CC=C32)NC(=O)C(CCCNC(=N)N)NC(=O)C(CC4=CC=CC=C4)NC(=O)C(CC5=CN=CN5)NC(=O)C(CCC(=O)O)NC(=O)C(CCSC)NC(=O)C(CO)NC(=O)C(CC6=CC=C(C=C6)O)NC(=O)C(CO)N Ambient -20°C "Berkovich R, Agius MA. Mechanisms of action of ACTH in the management of relapsing forms of multiple sclerosis. Ther Adv Neurol Disord. 2014 Mar;7(2):83-96. PMID: 24587825.

 

Isales CM, Zaidi M, Blair HC. ACTH is a novel regulator of bone mass. Ann N Y Acad Sci. 2010 Mar;1192:110-6. PMID: 20392225.

"

LKT A0965 Adrenocorticotropic Hormone (1-14) 1 mg 72.1 Endogenous peptide hormone fragment, involved in stress signaling; MC2 agonist. ACTH ≥95% 1680.9 C77H169N21O20S1 Ambient -20°C "Berkovich R, Agius MA. Mechanisms of action of ACTH in the management of relapsing forms of multiple sclerosis. Ther Adv Neurol Disord. 2014 Mar;7(2):83-96. PMID: 24587825.

 

Isales CM, Zaidi M, Blair HC. ACTH is a novel regulator of bone mass. Ann N Y Acad Sci. 2010 Mar;1192:110-6. PMID: 20392225.

"

LKT A0965 Adrenocorticotropic Hormone (1-14) 2 mg 123.1 Endogenous peptide hormone fragment, involved in stress signaling; MC2 agonist. ACTH ≥95% 1680.9 C77H169N21O20S1 Ambient -20°C "Berkovich R, Agius MA. Mechanisms of action of ACTH in the management of relapsing forms of multiple sclerosis. Ther Adv Neurol Disord. 2014 Mar;7(2):83-96. PMID: 24587825.

 

Isales CM, Zaidi M, Blair HC. ACTH is a novel regulator of bone mass. Ann N Y Acad Sci. 2010 Mar;1192:110-6. PMID: 20392225.

"

LKT A0965 Adrenocorticotropic Hormone (1-14) 5 mg 216.1 Endogenous peptide hormone fragment, involved in stress signaling; MC2 agonist. ACTH ≥95% 1680.9 C77H169N21O20S1 Ambient -20°C "Berkovich R, Agius MA. Mechanisms of action of ACTH in the management of relapsing forms of multiple sclerosis. Ther Adv Neurol Disord. 2014 Mar;7(2):83-96. PMID: 24587825.

 

Isales CM, Zaidi M, Blair HC. ACTH is a novel regulator of bone mass. Ann N Y Acad Sci. 2010 Mar;1192:110-6. PMID: 20392225.

"

LKT A0966 Adrenocorticotropic Hormone (1-16), human 0.5 mg 83.9 Endogenous peptide hormone fragment, involved in stress signaling; MC2 agonist. ACTH ≥95% 1937.27 C89H133N25O22S CC(C)C(C(=O)NCC(=O)NC(CCCCN)C(=O)NC(CCCCN)C(=O)O)NC(=O)C1CCCN1C(=O)C(CCCCN)NC(=O)CNC(=O)C(CC2=CNC3=CC=CC=C32)NC(=O)C(CCCNC(=N)N)NC(=O)C(CC4=CC=CC=C4)NC(=O)C(CC5=CN=CN5)NC(=O)C(CCC(=O)O)NC(=O)C(CCSC)NC(=O)C(CO)NC(=O)C(CC6=CC=C(C=C6)O)NC(=O)C(CO)N Ambient -20°C "Berkovich R, Agius MA. Mechanisms of action of ACTH in the management of relapsing forms of multiple sclerosis. Ther Adv Neurol Disord. 2014 Mar;7(2):83-96. PMID: 24587825.

 

Isales CM, Zaidi M, Blair HC. ACTH is a novel regulator of bone mass. Ann N Y Acad Sci. 2010 Mar;1192:110-6. PMID: 20392225.

"

LKT A0966 Adrenocorticotropic Hormone (1-16), human 1 mg 144 Endogenous peptide hormone fragment, involved in stress signaling; MC2 agonist. ACTH ≥95% 1937.27 C89H133N25O22S CC(C)C(C(=O)NCC(=O)NC(CCCCN)C(=O)NC(CCCCN)C(=O)O)NC(=O)C1CCCN1C(=O)C(CCCCN)NC(=O)CNC(=O)C(CC2=CNC3=CC=CC=C32)NC(=O)C(CCCNC(=N)N)NC(=O)C(CC4=CC=CC=C4)NC(=O)C(CC5=CN=CN5)NC(=O)C(CCC(=O)O)NC(=O)C(CCSC)NC(=O)C(CO)NC(=O)C(CC6=CC=C(C=C6)O)NC(=O)C(CO)N Ambient -20°C "Berkovich R, Agius MA. Mechanisms of action of ACTH in the management of relapsing forms of multiple sclerosis. Ther Adv Neurol Disord. 2014 Mar;7(2):83-96. PMID: 24587825.

 

Isales CM, Zaidi M, Blair HC. ACTH is a novel regulator of bone mass. Ann N Y Acad Sci. 2010 Mar;1192:110-6. PMID: 20392225.

"

LKT A0966 Adrenocorticotropic Hormone (1-16), human 2.5 mg 252.1 Endogenous peptide hormone fragment, involved in stress signaling; MC2 agonist. ACTH ≥95% 1937.27 C89H133N25O22S CC(C)C(C(=O)NCC(=O)NC(CCCCN)C(=O)NC(CCCCN)C(=O)O)NC(=O)C1CCCN1C(=O)C(CCCCN)NC(=O)CNC(=O)C(CC2=CNC3=CC=CC=C32)NC(=O)C(CCCNC(=N)N)NC(=O)C(CC4=CC=CC=C4)NC(=O)C(CC5=CN=CN5)NC(=O)C(CCC(=O)O)NC(=O)C(CCSC)NC(=O)C(CO)NC(=O)C(CC6=CC=C(C=C6)O)NC(=O)C(CO)N Ambient -20°C "Berkovich R, Agius MA. Mechanisms of action of ACTH in the management of relapsing forms of multiple sclerosis. Ther Adv Neurol Disord. 2014 Mar;7(2):83-96. PMID: 24587825.

 

Isales CM, Zaidi M, Blair HC. ACTH is a novel regulator of bone mass. Ann N Y Acad Sci. 2010 Mar;1192:110-6. PMID: 20392225.

"

LKT A0967 Adrenocorticotropic Hormone (1-17), human 0.5 mg 83.9 Endogenous peptide hormone fragment, involved in stress signaling; MC2 agonist. ACTH ≥95% 2093.5 C95H145N29O23S Ambient -20°C "Berkovich R, Agius MA. Mechanisms of action of ACTH in the management of relapsing forms of multiple sclerosis. Ther Adv Neurol Disord. 2014 Mar;7(2):83-96. PMID: 24587825.

 

Isales CM, Zaidi M, Blair HC. ACTH is a novel regulator of bone mass. Ann N Y Acad Sci. 2010 Mar;1192:110-6. PMID: 20392225.

"

LKT A0967 Adrenocorticotropic Hormone (1-17), human 1 mg 144 Endogenous peptide hormone fragment, involved in stress signaling; MC2 agonist. ACTH ≥95% 2093.5 C95H145N29O23S Ambient -20°C "Berkovich R, Agius MA. Mechanisms of action of ACTH in the management of relapsing forms of multiple sclerosis. Ther Adv Neurol Disord. 2014 Mar;7(2):83-96. PMID: 24587825.

 

Isales CM, Zaidi M, Blair HC. ACTH is a novel regulator of bone mass. Ann N Y Acad Sci. 2010 Mar;1192:110-6. PMID: 20392225.

"

LKT A0967 Adrenocorticotropic Hormone (1-17), human 2.5 mg 252.1 Endogenous peptide hormone fragment, involved in stress signaling; MC2 agonist. ACTH ≥95% 2093.5 C95H145N29O23S Ambient -20°C "Berkovich R, Agius MA. Mechanisms of action of ACTH in the management of relapsing forms of multiple sclerosis. Ther Adv Neurol Disord. 2014 Mar;7(2):83-96. PMID: 24587825.

 

Isales CM, Zaidi M, Blair HC. ACTH is a novel regulator of bone mass. Ann N Y Acad Sci. 2010 Mar;1192:110-6. PMID: 20392225.

"

LKT A0968 Adrenocorticotropic Hormone (1-24), human 0.5 mg 83.9 Endogenous peptide hormone fragment, involved in stress signaling; MC2 agonist. ACTH ≥95% 2933.5 C136H210N40O31S Ambient -20°C "Berkovich R, Agius MA. Mechanisms of action of ACTH in the management of relapsing forms of multiple sclerosis. Ther Adv Neurol Disord. 2014 Mar;7(2):83-96. PMID: 24587825.

 

Isales CM, Zaidi M, Blair HC. ACTH is a novel regulator of bone mass. Ann N Y Acad Sci. 2010 Mar;1192:110-6. PMID: 20392225.

"

LKT A0968 Adrenocorticotropic Hormone (1-24), human 1 mg 144 Endogenous peptide hormone fragment, involved in stress signaling; MC2 agonist. ACTH ≥95% 2933.5 C136H210N40O31S Ambient -20°C "Berkovich R, Agius MA. Mechanisms of action of ACTH in the management of relapsing forms of multiple sclerosis. Ther Adv Neurol Disord. 2014 Mar;7(2):83-96. PMID: 24587825.

 

Isales CM, Zaidi M, Blair HC. ACTH is a novel regulator of bone mass. Ann N Y Acad Sci. 2010 Mar;1192:110-6. PMID: 20392225.

"

LKT A0968 Adrenocorticotropic Hormone (1-24), human 2.5 mg 252.1 Endogenous peptide hormone fragment, involved in stress signaling; MC2 agonist. ACTH ≥95% 2933.5 C136H210N40O31S Ambient -20°C "Berkovich R, Agius MA. Mechanisms of action of ACTH in the management of relapsing forms of multiple sclerosis. Ther Adv Neurol Disord. 2014 Mar;7(2):83-96. PMID: 24587825.

 

Isales CM, Zaidi M, Blair HC. ACTH is a novel regulator of bone mass. Ann N Y Acad Sci. 2010 Mar;1192:110-6. PMID: 20392225.

"

LKT A0970 Adrenocorticotropic Hormone (18-39), human 1 mg 156 Endogenous peptide hormone fragment, involved in stress signaling; MC2 agonist. ACTH ≥95% 2465.7 C112H165N27O36 Ambient -20°C "Berkovich R, Agius MA. Mechanisms of action of ACTH in the management of relapsing forms of multiple sclerosis. Ther Adv Neurol Disord. 2014 Mar;7(2):83-96. PMID: 24587825.

 

Isales CM, Zaidi M, Blair HC. ACTH is a novel regulator of bone mass. Ann N Y Acad Sci. 2010 Mar;1192:110-6. PMID: 20392225.

" Not dangerous goods.

LKT A0970 Adrenocorticotropic Hormone (18-39), human 2 mg 264.1 Endogenous peptide hormone fragment, involved in stress signaling; MC2 agonist. ACTH ≥95% 2465.7 C112H165N27O36 Ambient -20°C "Berkovich R, Agius MA. Mechanisms of action of ACTH in the management of relapsing forms of multiple sclerosis. Ther Adv Neurol Disord. 2014 Mar;7(2):83-96. PMID: 24587825.

 

Isales CM, Zaidi M, Blair HC. ACTH is a novel regulator of bone mass. Ann N Y Acad Sci. 2010 Mar;1192:110-6. PMID: 20392225.

" Not dangerous goods.

LKT A0970 Adrenocorticotropic Hormone (18-39), human 5 mg 468.2 Endogenous peptide hormone fragment, involved in stress signaling; MC2 agonist. ACTH ≥95% 2465.7 C112H165N27O36 Ambient -20°C "Berkovich R, Agius MA. Mechanisms of action of ACTH in the management of relapsing forms of multiple sclerosis. Ther Adv Neurol Disord. 2014 Mar;7(2):83-96. PMID: 24587825.

 

Isales CM, Zaidi M, Blair HC. ACTH is a novel regulator of bone mass. Ann N Y Acad Sci. 2010 Mar;1192:110-6. PMID: 20392225.

" Not dangerous goods.

LKT A0971 Adrenocorticotropic Hormone (4-10), human 1 mg 60 Endogenous peptide hormone fragment, involved in stress signaling; MC2 agonist. ACTH 4037-01-8 ≥95% 962.1 C44H59N13O10S1 CSCCC(C(=O)NC(CCC(=O)O)C(=O)NC(CC1=CN=CN1)C(=O)NC(CC2=CC=CC=C2)C(=O)NC(CCCN=C(N)N)C(=O)NC(CC3=CNC4=CC=CC=C43)C(=O)NCC(=O)O)N Ambient -20°C "Berkovich R, Agius MA. Mechanisms of action of ACTH in the management of relapsing forms of multiple sclerosis. Ther Adv Neurol Disord. 2014 Mar;7(2):83-96. PMID: 24587825.

 

Isales CM, Zaidi M, Blair HC. ACTH is a novel regulator of bone mass. Ann N Y Acad Sci. 2010 Mar;1192:110-6. PMID: 20392225.

" Not dangerous goods.

LKT A0971 Adrenocorticotropic Hormone (4-10), human 2 mg 101.9 Endogenous peptide hormone fragment, involved in stress signaling; MC2 agonist. ACTH 4037-01-8 ≥95% 962.1 C44H59N13O10S1 CSCCC(C(=O)NC(CCC(=O)O)C(=O)NC(CC1=CN=CN1)C(=O)NC(CC2=CC=CC=C2)C(=O)NC(CCCN=C(N)N)C(=O)NC(CC3=CNC4=CC=CC=C43)C(=O)NCC(=O)O)N Ambient -20°C "Berkovich R, Agius MA. Mechanisms of action of ACTH in the management of relapsing forms of multiple sclerosis. Ther Adv Neurol Disord. 2014 Mar;7(2):83-96. PMID: 24587825.

 

Isales CM, Zaidi M, Blair HC. ACTH is a novel regulator of bone mass. Ann N Y Acad Sci. 2010 Mar;1192:110-6. PMID: 20392225.

" Not dangerous goods.

LKT A0971 Adrenocorticotropic Hormone (4-10), human 5 mg 180 Endogenous peptide hormone fragment, involved in stress signaling; MC2 agonist. ACTH 4037-01-8 ≥95% 962.1 C44H59N13O10S1 CSCCC(C(=O)NC(CCC(=O)O)C(=O)NC(CC1=CN=CN1)C(=O)NC(CC2=CC=CC=C2)C(=O)NC(CCCN=C(N)N)C(=O)NC(CC3=CNC4=CC=CC=C43)C(=O)NCC(=O)O)N Ambient -20°C "Berkovich R, Agius MA. Mechanisms of action of ACTH in the management of relapsing forms of multiple sclerosis. Ther Adv Neurol Disord. 2014 Mar;7(2):83-96. PMID: 24587825.

 

Isales CM, Zaidi M, Blair HC. ACTH is a novel regulator of bone mass. Ann N Y Acad Sci. 2010 Mar;1192:110-6. PMID: 20392225.

" Not dangerous goods.

LKT A0978 Actinonin 5 mg 197.1 Peptide deformylase, MMP meprin A, aminopeptidase N (CD13) inhibitor. 3-((1-((2-[Hydroxymethyl]-1-pyrrolidinyl)carbonyl)-2-methylpropyl)carbamoyl)octanohydroxamic acid Actinonine 13434-13-4 ≥98% 385.5 C19H35N3O5 CCCCCC(CC(=O)NO)C(=O)NC(C(C)C)C(=O)N1CCCC1CO Ambient -20°C Soluble in ethanol. "Sheth A, Escobar-Alvarez S, Gardner J, et al. Inhibition of human mitochondrial peptide deformylase causes apoptosis in c-myc-overexpressing hematopoietic cancers. Cell Death Dis. 2014 Mar 27;5:e1152. PMID: 24675470.

 

Goemaere E, Melet A, Larue V, et al. New peptide deformylase inhibitors and cooperative interaction: a combination to improve antibacterial activity. J Antimicrob Chemother. 2012 Jun;67(6):1392-400. PMID: 22378679.

 

Wang Z, Herzog C, Kaushal GP, et al. Actinonin, a meprin A inhibitor, protects the renal microcirculation during sepsis. Shock. 2011 Feb;35(2):141-7. PMID: 20577148.

 

Sharma A, Sharma S, Khuller GK, et al. In vitro and ex vivo activity of peptide deformylase inhibitors against Mycobacterium tuberculosis H37Rv. Int J Antimicrob Agents. 2009 Sep;34(3):226-30. PMID: 19505802.

 

Sina A, Lord-Dufour S, Annabi B. Cell-based evidence for aminopeptidase N/CD13 inhibitor actinonin targeting of MT1-MMP-mediated proMMP-2 activation. Cancer Lett. 2009 Jul 8;279(2):171-6. PMID: 19264392.

" Not dangerous goods.

LKT A1017 Aceclofenac 5 g 74 Diclofenac analog, NSAID; COX-2 inhibitor. "2-[(2,6-Dichlorophenyl)amino]benzeneacetic acid 

carboxymethyl ester 

" Airtal; Falcol; Gerbin; Preservex 89796-99-6 ≥98% 354.18 C16H13Cl2NO4 C1=CC=C(C(=C1)CC(=O)OCC(=O)O)NC2=C(C=CC=C2Cl)Cl Ambient Ambient Soluble in ethanol and acetone, insoluble in water "Chopade AR, Sayyad FJ, Naikwade NS. Pharmacological characterization of carrageenan induced heat muscle hyperalgesia in rats using non-selective, preferential and selective COX-2 inhibitors. Pharmacol Rep. 2014 Jun;66(3):353-62. PMID: 24905509.

 

González-Alvaro I, Carmona L, Díaz-González F, et al. Aceclofenac, a new nonsteroidal antiinflammatory drug, decreases the expression and function of some adhesion molecules on human neutrophils. J Rheumatol. 1996 Apr;23(4):723-9. PMID: 8730134.

" Xn "UN number: 2811     Class:  6.1     Packing group:  III

Proper shipping name:  Toxic solids, organic, n.o.s. (ACECLOFENAC)

Reportable Quantity (RQ):     Marine pollutant:  No     Poison inhalation hazard:  No."

LKT A1017 Aceclofenac 25 g 288.8 Diclofenac analog, NSAID; COX-2 inhibitor. "2-[(2,6-Dichlorophenyl)amino]benzeneacetic acid 

carboxymethyl ester 

" Airtal; Falcol; Gerbin; Preservex 89796-99-6 ≥98% 354.18 C16H13Cl2NO4 C1=CC=C(C(=C1)CC(=O)OCC(=O)O)NC2=C(C=CC=C2Cl)Cl Ambient Ambient Soluble in ethanol and acetone, insoluble in water "Chopade AR, Sayyad FJ, Naikwade NS. Pharmacological characterization of carrageenan induced heat muscle hyperalgesia in rats using non-selective, preferential and selective COX-2 inhibitors. Pharmacol Rep. 2014 Jun;66(3):353-62. PMID: 24905509.

 

González-Alvaro I, Carmona L, Díaz-González F, et al. Aceclofenac, a new nonsteroidal antiinflammatory drug, decreases the expression and function of some adhesion molecules on human neutrophils. J Rheumatol. 1996 Apr;23(4):723-9. PMID: 8730134.

" Xn "UN number: 2811     Class:  6.1     Packing group:  III

Proper shipping name:  Toxic solids, organic, n.o.s. (ACECLOFENAC)

Reportable Quantity (RQ):     Marine pollutant:  No     Poison inhalation hazard:  No."

LKT A1017 Aceclofenac 100 g 618.9 Diclofenac analog, NSAID; COX-2 inhibitor. "2-[(2,6-Dichlorophenyl)amino]benzeneacetic acid 

carboxymethyl ester 

" Airtal; Falcol; Gerbin; Preservex 89796-99-6 ≥98% 354.18 C16H13Cl2NO4 C1=CC=C(C(=C1)CC(=O)OCC(=O)O)NC2=C(C=CC=C2Cl)Cl Ambient Ambient Soluble in ethanol and acetone, insoluble in water "Chopade AR, Sayyad FJ, Naikwade NS. Pharmacological characterization of carrageenan induced heat muscle hyperalgesia in rats using non-selective, preferential and selective COX-2 inhibitors. Pharmacol Rep. 2014 Jun;66(3):353-62. PMID: 24905509.

 

González-Alvaro I, Carmona L, Díaz-González F, et al. Aceclofenac, a new nonsteroidal antiinflammatory drug, decreases the expression and function of some adhesion molecules on human neutrophils. J Rheumatol. 1996 Apr;23(4):723-9. PMID: 8730134.

" Xn "UN number: 2811     Class:  6.1     Packing group:  III

Proper shipping name:  Toxic solids, organic, n.o.s. (ACECLOFENAC)

Reportable Quantity (RQ):     Marine pollutant:  No     Poison inhalation hazard:  No."

LKT A1084 Ac-VEID-pNA 25 mg 1275.2 Caspase 6 substrate. ≥95% 636.6 C28H40N6O11 Ambient -20°C DMSO Kanazawa T, Kono T, Watanabe M, et al. Bcl-2 blocks apoptosis caused by pierisin-1, a guanine-specific ADP-ribosylating toxin from the cabbage butterfly. Biochem Biophys Res Commun. 2002 Aug 9;296(1):20-5. PMID: 12147221. Not dangerous goods.

LKT A1096 Acyclovir 50 mg 96.6 Nucleoside (guanosine) analog; DNA chain terminator, viral DNA polymerase and D-amino oxidase inhibitor. Acycloguanosine; Vipral; Zovirax 59277-89-3 ≥98% 225.2 C8H11N5O3 C1=NC2=C(N1COCCO)NC(=NC2=O)N Ambient Ambient MeOH, Poor solubility in water. "James SH, Prichard MN. Current and future therapies for herpes simplex virus infections: mechanism of action and drug resistance. Curr Opin Virol. 2014 Jul 15;8C:54-61. PMID: 25036916.

 

Katane M, Matsuda S, Saitoh Y, et al. The antiviral drug acyclovir is a slow-binding inhibitor of (D)-amino acid oxidase. Biochemistry. 2013 Aug 20;52(33):5665-74. PMID: 23859606.

 

Elion GB. Mechanism of action and selectivity of acyclovir. Am J Med. 1982 Jul 20;73(1A):7-13. PMID: 6285736.

" None Not dangerous goods.

LKT A1096 Acyclovir 100 mg 173.3 Nucleoside (guanosine) analog; DNA chain terminator, viral DNA polymerase and D-amino oxidase inhibitor. Acycloguanosine; Vipral; Zovirax 59277-89-3 ≥98% 225.2 C8H11N5O3 C1=NC2=C(N1COCCO)NC(=NC2=O)N Ambient Ambient MeOH, Poor solubility in water. "James SH, Prichard MN. Current and future therapies for herpes simplex virus infections: mechanism of action and drug resistance. Curr Opin Virol. 2014 Jul 15;8C:54-61. PMID: 25036916.

 

Katane M, Matsuda S, Saitoh Y, et al. The antiviral drug acyclovir is a slow-binding inhibitor of (D)-amino acid oxidase. Biochemistry. 2013 Aug 20;52(33):5665-74. PMID: 23859606.

 

Elion GB. Mechanism of action and selectivity of acyclovir. Am J Med. 1982 Jul 20;73(1A):7-13. PMID: 6285736.

" None Not dangerous goods.

LKT A1096 Acyclovir 500 mg 624.8 Nucleoside (guanosine) analog; DNA chain terminator, viral DNA polymerase and D-amino oxidase inhibitor. Acycloguanosine; Vipral; Zovirax 59277-89-3 ≥98% 225.2 C8H11N5O3 C1=NC2=C(N1COCCO)NC(=NC2=O)N Ambient Ambient MeOH, Poor solubility in water. "James SH, Prichard MN. Current and future therapies for herpes simplex virus infections: mechanism of action and drug resistance. Curr Opin Virol. 2014 Jul 15;8C:54-61. PMID: 25036916.

 

Katane M, Matsuda S, Saitoh Y, et al. The antiviral drug acyclovir is a slow-binding inhibitor of (D)-amino acid oxidase. Biochemistry. 2013 Aug 20;52(33):5665-74. PMID: 23859606.

 

Elion GB. Mechanism of action and selectivity of acyclovir. Am J Med. 1982 Jul 20;73(1A):7-13. PMID: 6285736.

" None Not dangerous goods.

LKT A1097 Ac-YVAD-pNA 25 mg 1275.2 Caspase 1 substrate. ≥95% 628.6 C29H36N6O10 Ambient -20°C DMSO "Pereira NA, Song Z. Some commonly used caspase substrates and inhibitors lack the specificity required to monitor individual caspase activity. Biochem Biophys Res Commun. 2008 Dec 19;377(3):873-7. PMID: 18976637.

 

Eckert A, Steiner B, Marques C, et al. Elevated vulnerability to oxidative stress-induced cell death and activation of caspase-3 by the Swedish amyloid precursor protein mutation. J Neurosci Res. 2001 Apr 15;64(2):183-92. PMID: 11288146.

" Not dangerous goods.

LKT A1202 Adapalene 100 mg 142.4 Tretinoin analog; RARα/β/γ agonist. 106685-40-9 ≥98% 412.52 C28H28O3 COC1=C(C=C(C=C1)C2=CC3=C(C=C2)C=C(C=C3)C(=O)O)C45CC6CC(C4)CC(C6)C5 Ambient Ambient "Tirado-Sánchez A, Espíndola YS, Ponce-Olivera RM, et al. Efficacy and safety of adapalene gel 0.1% and 0.3% and tretinoin gel 0.05% for acne vulgaris: results of a single-center, randomized, double-blinded, placebo-controlled clinical trial on Mexican patients (skin type III-IV). J Cosmet Dermatol. 2013 Jun;12(2):103-7. PMID: 23725303.

 

Shi TW, Ren XK, Yu HX, et al. Roles of adapalene in the treatment of pityriasis versicolor. Dermatology. 2012;224(2):184-8. PMID: 22572567.

 

Zuliani T, Khammari A, Chaussy H, et al. Ex vivo demonstration of a synergistic effect of Adapalene and benzoyl peroxide on inflammatory acne lesions. Exp Dermatol. 2011 Oct;20(10):850-3. PMID: 21793939.

 

Michel S, Jomard A, Démarchez M. Pharmacology of adapalene. Br J Dermatol. 1998 Oct;139 Suppl 52:3-7. PMID: 9990413.

 

Bernard BA. Adapalene, a new chemical entity with retinoid activity. Skin Pharmacol. 1993;6 Suppl 1:61-9. PMID: 8142113.

" None Not dangerous goods.

LKT A1202 Adapalene 250 mg 251.3 Tretinoin analog; RARα/β/γ agonist. 106685-40-9 ≥98% 412.52 C28H28O3 COC1=C(C=C(C=C1)C2=CC3=C(C=C2)C=C(C=C3)C(=O)O)C45CC6CC(C4)CC(C6)C5 Ambient Ambient "Tirado-Sánchez A, Espíndola YS, Ponce-Olivera RM, et al. Efficacy and safety of adapalene gel 0.1% and 0.3% and tretinoin gel 0.05% for acne vulgaris: results of a single-center, randomized, double-blinded, placebo-controlled clinical trial on Mexican patients (skin type III-IV). J Cosmet Dermatol. 2013 Jun;12(2):103-7. PMID: 23725303.

 

Shi TW, Ren XK, Yu HX, et al. Roles of adapalene in the treatment of pityriasis versicolor. Dermatology. 2012;224(2):184-8. PMID: 22572567.

 

Zuliani T, Khammari A, Chaussy H, et al. Ex vivo demonstration of a synergistic effect of Adapalene and benzoyl peroxide on inflammatory acne lesions. Exp Dermatol. 2011 Oct;20(10):850-3. PMID: 21793939.

 

Michel S, Jomard A, Démarchez M. Pharmacology of adapalene. Br J Dermatol. 1998 Oct;139 Suppl 52:3-7. PMID: 9990413.

 

Bernard BA. Adapalene, a new chemical entity with retinoid activity. Skin Pharmacol. 1993;6 Suppl 1:61-9. PMID: 8142113.

" None Not dangerous goods.

LKT A1202 Adapalene 1 g 636.3 Tretinoin analog; RARα/β/γ agonist. 106685-40-9 ≥98% 412.52 C28H28O3 COC1=C(C=C(C=C1)C2=CC3=C(C=C2)C=C(C=C3)C(=O)O)C45CC6CC(C4)CC(C6)C5 Ambient Ambient "Tirado-Sánchez A, Espíndola YS, Ponce-Olivera RM, et al. Efficacy and safety of adapalene gel 0.1% and 0.3% and tretinoin gel 0.05% for acne vulgaris: results of a single-center, randomized, double-blinded, placebo-controlled clinical trial on Mexican patients (skin type III-IV). J Cosmet Dermatol. 2013 Jun;12(2):103-7. PMID: 23725303.

 

Shi TW, Ren XK, Yu HX, et al. Roles of adapalene in the treatment of pityriasis versicolor. Dermatology. 2012;224(2):184-8. PMID: 22572567.

 

Zuliani T, Khammari A, Chaussy H, et al. Ex vivo demonstration of a synergistic effect of Adapalene and benzoyl peroxide on inflammatory acne lesions. Exp Dermatol. 2011 Oct;20(10):850-3. PMID: 21793939.

 

Michel S, Jomard A, Démarchez M. Pharmacology of adapalene. Br J Dermatol. 1998 Oct;139 Suppl 52:3-7. PMID: 9990413.

 

Bernard BA. Adapalene, a new chemical entity with retinoid activity. Skin Pharmacol. 1993;6 Suppl 1:61-9. PMID: 8142113.

" None Not dangerous goods.

LKT A1318 Adenine 10 g 63.3 Endogenous purine nucleotide base, required for synthesis of ATP, NAD, FAD, DNA, and RNA. 1H-Purin-6-amine 1,6-Dihydro-6-iminopurine; Leuco-4; Vitamin B4 73-24-5 ≥98% 135.13 C5H5N5 C1=NC2=C(N1)C(=NC=N2)N Ambient Ambient Slightly soluble in alcohol or water. Insoluble in ether or chloroform. "Nakamura M, Bhatnagar A, Sadoshima J. Overview of pyridine nucleotides review series. Circ Res. 2012 Aug 17;111(5):604-10. PMID: 22904040.

 

Klingenberg M. Molecular aspects of the adenine nucleotide carrier from mitochondria. Arch Biochem Biophys. 1989 Apr;270(1):1-14. PMID: 2648994.

 

Bloch A. The structure of nucleosides in relation to their biological and and biochemical activity: a summary. Ann N Y Acad Sci. 1975 Aug 8;255:576-96. PMID: 53023.

" Xn, Xi "UN number: 2811     Class:  6.1     Packing group:  III

Proper shipping name:  Toxic solids, organic, n.o.s. (Adenine)

Marine pollutant:  No     Poison inhalation hazard:  No"

LKT A1318 Adenine 25 g 115.4 Endogenous purine nucleotide base, required for synthesis of ATP, NAD, FAD, DNA, and RNA. 1H-Purin-6-amine 1,6-Dihydro-6-iminopurine; Leuco-4; Vitamin B4 73-24-5 ≥98% 135.13 C5H5N5 C1=NC2=C(N1)C(=NC=N2)N Ambient Ambient Slightly soluble in alcohol or water. Insoluble in ether or chloroform. "Nakamura M, Bhatnagar A, Sadoshima J. Overview of pyridine nucleotides review series. Circ Res. 2012 Aug 17;111(5):604-10. PMID: 22904040.

 

Klingenberg M. Molecular aspects of the adenine nucleotide carrier from mitochondria. Arch Biochem Biophys. 1989 Apr;270(1):1-14. PMID: 2648994.

 

Bloch A. The structure of nucleosides in relation to their biological and and biochemical activity: a summary. Ann N Y Acad Sci. 1975 Aug 8;255:576-96. PMID: 53023.

" Xn, Xi "UN number: 2811     Class:  6.1     Packing group:  III

Proper shipping name:  Toxic solids, organic, n.o.s. (Adenine)

Marine pollutant:  No     Poison inhalation hazard:  No"

LKT A1319 Adenosine Triphosphate Disodium Hydrate 1 g 46.4 Endogenous coenzyme, unit of cellular energy, required for production of nucleic acids, cAMP, and other signal transduction molecules. Adenosine 5'-(tetrahydrogen triphosphate) disodium salt Adenosine Triphosphate Disodium Salt; Adetphos; Atenen; Circulen; Trinosin 987-65-5 ≥95% 551.14 C10H16N5Na2O13P3 C1=NC2=C(C(=N1)N)N=CN2C3C(C(C(O3)COP(=O)(O)OP(=O)([O-])OP(=O)(O)[O-])O)O.[Na+].[Na+] Protect from light. Hygroscopic. Ambient -20°C Soluble in water (50mg/mL). "Sakuma T, Motoda C, Tokuyama T, et al. Exogenous adenosine triphosphate disodium administration during primary percutaneous coronary intervention reduces no-reflow and preserves left ventricular function in patients with acute anterior myocardial infarction: a study using myocardial contrast echocardiography. Int J Cardiol. 2010 Apr 15;140(2):200-9. PMID: 19081151.

 

Tokuyama T, Sakuma T, Motoda C, et al. Intravenous administration of adenosine triphosphate disodium during primary percutaneous coronary intervention attenuates the transient rapid improvement of myocardial wall motion, not myocardial stunning, shortly after recanalization in acute anterior myocardial infarction. J Cardiol. 2009 Oct;54(2):289-96. PMID: 19782267.

 

Törnroth-Horsefield S, Neutze R. Opening and closing the metabolite gate. Proc Natl Acad Sci U S A. 2008 Dec 16;105(50):19565-6. PMID: 19073922.

 

Knowles JR. Enzyme-catalyzed phosphoryl transfer reactions. Annu Rev Biochem. 1980;49:877-919. PMID: 6250450.

" Not dangerous goods.

LKT A1319 Adenosine Triphosphate Disodium Hydrate 5 g 111 Endogenous coenzyme, unit of cellular energy, required for production of nucleic acids, cAMP, and other signal transduction molecules. Adenosine 5'-(tetrahydrogen triphosphate) disodium salt Adenosine Triphosphate Disodium Salt; Adetphos; Atenen; Circulen; Trinosin 987-65-5 ≥95% 551.14 C10H16N5Na2O13P3 C1=NC2=C(C(=N1)N)N=CN2C3C(C(C(O3)COP(=O)(O)OP(=O)([O-])OP(=O)(O)[O-])O)O.[Na+].[Na+] Protect from light. Hygroscopic. Ambient -20°C Soluble in water (50mg/mL). "Sakuma T, Motoda C, Tokuyama T, et al. Exogenous adenosine triphosphate disodium administration during primary percutaneous coronary intervention reduces no-reflow and preserves left ventricular function in patients with acute anterior myocardial infarction: a study using myocardial contrast echocardiography. Int J Cardiol. 2010 Apr 15;140(2):200-9. PMID: 19081151.

 

Tokuyama T, Sakuma T, Motoda C, et al. Intravenous administration of adenosine triphosphate disodium during primary percutaneous coronary intervention attenuates the transient rapid improvement of myocardial wall motion, not myocardial stunning, shortly after recanalization in acute anterior myocardial infarction. J Cardiol. 2009 Oct;54(2):289-96. PMID: 19782267.

 

Törnroth-Horsefield S, Neutze R. Opening and closing the metabolite gate. Proc Natl Acad Sci U S A. 2008 Dec 16;105(50):19565-6. PMID: 19073922.

 

Knowles JR. Enzyme-catalyzed phosphoryl transfer reactions. Annu Rev Biochem. 1980;49:877-919. PMID: 6250450.

" Not dangerous goods.

LKT A1319 Adenosine Triphosphate Disodium Hydrate 10 g 180.2 Endogenous coenzyme, unit of cellular energy, required for production of nucleic acids, cAMP, and other signal transduction molecules. Adenosine 5'-(tetrahydrogen triphosphate) disodium salt Adenosine Triphosphate Disodium Salt; Adetphos; Atenen; Circulen; Trinosin 987-65-5 ≥95% 551.14 C10H16N5Na2O13P3 C1=NC2=C(C(=N1)N)N=CN2C3C(C(C(O3)COP(=O)(O)OP(=O)([O-])OP(=O)(O)[O-])O)O.[Na+].[Na+] Protect from light. Hygroscopic. Ambient -20°C Soluble in water (50mg/mL). "Sakuma T, Motoda C, Tokuyama T, et al. Exogenous adenosine triphosphate disodium administration during primary percutaneous coronary intervention reduces no-reflow and preserves left ventricular function in patients with acute anterior myocardial infarction: a study using myocardial contrast echocardiography. Int J Cardiol. 2010 Apr 15;140(2):200-9. PMID: 19081151.

 

Tokuyama T, Sakuma T, Motoda C, et al. Intravenous administration of adenosine triphosphate disodium during primary percutaneous coronary intervention attenuates the transient rapid improvement of myocardial wall motion, not myocardial stunning, shortly after recanalization in acute anterior myocardial infarction. J Cardiol. 2009 Oct;54(2):289-96. PMID: 19782267.

 

Törnroth-Horsefield S, Neutze R. Opening and closing the metabolite gate. Proc Natl Acad Sci U S A. 2008 Dec 16;105(50):19565-6. PMID: 19073922.

 

Knowles JR. Enzyme-catalyzed phosphoryl transfer reactions. Annu Rev Biochem. 1980;49:877-919. PMID: 6250450.

" Not dangerous goods.

LKT A1319 Adenosine Triphosphate Disodium Hydrate 25 g 376.1 Endogenous coenzyme, unit of cellular energy, required for production of nucleic acids, cAMP, and other signal transduction molecules. Adenosine 5'-(tetrahydrogen triphosphate) disodium salt Adenosine Triphosphate Disodium Salt; Adetphos; Atenen; Circulen; Trinosin 987-65-5 ≥95% 551.14 C10H16N5Na2O13P3 C1=NC2=C(C(=N1)N)N=CN2C3C(C(C(O3)COP(=O)(O)OP(=O)([O-])OP(=O)(O)[O-])O)O.[Na+].[Na+] Protect from light. Hygroscopic. Ambient -20°C Soluble in water (50mg/mL). "Sakuma T, Motoda C, Tokuyama T, et al. Exogenous adenosine triphosphate disodium administration during primary percutaneous coronary intervention reduces no-reflow and preserves left ventricular function in patients with acute anterior myocardial infarction: a study using myocardial contrast echocardiography. Int J Cardiol. 2010 Apr 15;140(2):200-9. PMID: 19081151.

 

Tokuyama T, Sakuma T, Motoda C, et al. Intravenous administration of adenosine triphosphate disodium during primary percutaneous coronary intervention attenuates the transient rapid improvement of myocardial wall motion, not myocardial stunning, shortly after recanalization in acute anterior myocardial infarction. J Cardiol. 2009 Oct;54(2):289-96. PMID: 19782267.

 

Törnroth-Horsefield S, Neutze R. Opening and closing the metabolite gate. Proc Natl Acad Sci U S A. 2008 Dec 16;105(50):19565-6. PMID: 19073922.

 

Knowles JR. Enzyme-catalyzed phosphoryl transfer reactions. Annu Rev Biochem. 1980;49:877-919. PMID: 6250450.

" Not dangerous goods.

LKT A1330 Adipokinetic Hormone 1 mg 60 Neuropeptide hormone found in insects, involved in circadian rhythms. ≥95% 921 C44H60N10O12 Ambient -20°C "Metaxakis A, Tain LS, Grönke S, et al. Lowered insulin signalling ameliorates age-related sleep fragmentation in Drosophila. PLoS Biol. 2014 Apr 1;12(4):e1001824. PMID: 24690889.

 

Vinokurov K, Bednářová A, Tomčala A, et al. Role of adipokinetic hormone in stimulation of salivary gland activities: the fire bug Pyrrhocoris apterus L. (Heteroptera) as a model species. J Insect Physiol. 2014 Jan;60:58-67. PMID: 24269343.

 

Bednářová A, Kodrík D, Krishnan N. Adipokinetic hormone exerts its anti-oxidative effects using a conserved signal-transduction mechanism involving both PKC and cAMP by mobilizing extra- and intracellular Ca2+ stores. Comp Biochem Physiol C Toxicol Pharmacol. 2013 Sep;158(3):142-9. PMID: 23845878.

" Not dangerous goods.

LKT A1330 Adipokinetic Hormone 2 mg 101.9 Neuropeptide hormone found in insects, involved in circadian rhythms. ≥95% 921 C44H60N10O12 Ambient -20°C "Metaxakis A, Tain LS, Grönke S, et al. Lowered insulin signalling ameliorates age-related sleep fragmentation in Drosophila. PLoS Biol. 2014 Apr 1;12(4):e1001824. PMID: 24690889.

 

Vinokurov K, Bednářová A, Tomčala A, et al. Role of adipokinetic hormone in stimulation of salivary gland activities: the fire bug Pyrrhocoris apterus L. (Heteroptera) as a model species. J Insect Physiol. 2014 Jan;60:58-67. PMID: 24269343.

 

Bednářová A, Kodrík D, Krishnan N. Adipokinetic hormone exerts its anti-oxidative effects using a conserved signal-transduction mechanism involving both PKC and cAMP by mobilizing extra- and intracellular Ca2+ stores. Comp Biochem Physiol C Toxicol Pharmacol. 2013 Sep;158(3):142-9. PMID: 23845878.

" Not dangerous goods.

LKT A1330 Adipokinetic Hormone 5 mg 180 Neuropeptide hormone found in insects, involved in circadian rhythms. ≥95% 921 C44H60N10O12 Ambient -20°C "Metaxakis A, Tain LS, Grönke S, et al. Lowered insulin signalling ameliorates age-related sleep fragmentation in Drosophila. PLoS Biol. 2014 Apr 1;12(4):e1001824. PMID: 24690889.

 

Vinokurov K, Bednářová A, Tomčala A, et al. Role of adipokinetic hormone in stimulation of salivary gland activities: the fire bug Pyrrhocoris apterus L. (Heteroptera) as a model species. J Insect Physiol. 2014 Jan;60:58-67. PMID: 24269343.

 

Bednářová A, Kodrík D, Krishnan N. Adipokinetic hormone exerts its anti-oxidative effects using a conserved signal-transduction mechanism involving both PKC and cAMP by mobilizing extra- and intracellular Ca2+ stores. Comp Biochem Physiol C Toxicol Pharmacol. 2013 Sep;158(3):142-9. PMID: 23845878.

" Not dangerous goods.

LKT A1331 Adipokinetic Hormone, locust 1 mg 83.9 Neuropeptide hormone found in insects, involved in circadian rhythms. AKH ≥95% 1159.3 C54H74N14O15 Ambient -20°C "Metaxakis A, Tain LS, Grönke S, et al. Lowered insulin signalling ameliorates age-related sleep fragmentation in Drosophila. PLoS Biol. 2014 Apr 1;12(4):e1001824. PMID: 24690889.

 

Vinokurov K, Bednářová A, Tomčala A, et al. Role of adipokinetic hormone in stimulation of salivary gland activities: the fire bug Pyrrhocoris apterus L. (Heteroptera) as a model species. J Insect Physiol. 2014 Jan;60:58-67. PMID: 24269343.

 

Bednářová A, Kodrík D, Krishnan N. Adipokinetic hormone exerts its anti-oxidative effects using a conserved signal-transduction mechanism involving both PKC and cAMP by mobilizing extra- and intracellular Ca2+ stores. Comp Biochem Physiol C Toxicol Pharmacol. 2013 Sep;158(3):142-9. PMID: 23845878.

" Not dangerous goods.

LKT A1331 Adipokinetic Hormone, locust 2 mg 144 Neuropeptide hormone found in insects, involved in circadian rhythms. AKH ≥95% 1159.3 C54H74N14O15 Ambient -20°C "Metaxakis A, Tain LS, Grönke S, et al. Lowered insulin signalling ameliorates age-related sleep fragmentation in Drosophila. PLoS Biol. 2014 Apr 1;12(4):e1001824. PMID: 24690889.

 

Vinokurov K, Bednářová A, Tomčala A, et al. Role of adipokinetic hormone in stimulation of salivary gland activities: the fire bug Pyrrhocoris apterus L. (Heteroptera) as a model species. J Insect Physiol. 2014 Jan;60:58-67. PMID: 24269343.

 

Bednářová A, Kodrík D, Krishnan N. Adipokinetic hormone exerts its anti-oxidative effects using a conserved signal-transduction mechanism involving both PKC and cAMP by mobilizing extra- and intracellular Ca2+ stores. Comp Biochem Physiol C Toxicol Pharmacol. 2013 Sep;158(3):142-9. PMID: 23845878.

" Not dangerous goods.

LKT A1331 Adipokinetic Hormone, locust 5 mg 252.1 Neuropeptide hormone found in insects, involved in circadian rhythms. AKH ≥95% 1159.3 C54H74N14O15 Ambient -20°C "Metaxakis A, Tain LS, Grönke S, et al. Lowered insulin signalling ameliorates age-related sleep fragmentation in Drosophila. PLoS Biol. 2014 Apr 1;12(4):e1001824. PMID: 24690889.

 

Vinokurov K, Bednářová A, Tomčala A, et al. Role of adipokinetic hormone in stimulation of salivary gland activities: the fire bug Pyrrhocoris apterus L. (Heteroptera) as a model species. J Insect Physiol. 2014 Jan;60:58-67. PMID: 24269343.

 

Bednářová A, Kodrík D, Krishnan N. Adipokinetic hormone exerts its anti-oxidative effects using a conserved signal-transduction mechanism involving both PKC and cAMP by mobilizing extra- and intracellular Ca2+ stores. Comp Biochem Physiol C Toxicol Pharmacol. 2013 Sep;158(3):142-9. PMID: 23845878.

" Not dangerous goods.

LKT A1332 Adipokinetic Hormone II from Locusta migratoria 1 mg 83.9 Neuropeptide found in Locusta migratoria. ≥98% 903.9 C43H58N11O11 Ambient -20°C Soluble in water. Siegert K, Morgan P, Mordue W. Primary structures of locust adipokinetic hormones II. Biol Chem Hoppe Seyler. 1985 Aug;366(8):723-7. PMID: 4063072. Not dangerous goods.

LKT A1332 Adipokinetic Hormone II from Locusta migratoria 2 mg 144 Neuropeptide found in Locusta migratoria. ≥98% 903.9 C43H58N11O11 Ambient -20°C Soluble in water. Siegert K, Morgan P, Mordue W. Primary structures of locust adipokinetic hormones II. Biol Chem Hoppe Seyler. 1985 Aug;366(8):723-7. PMID: 4063072. Not dangerous goods.

LKT A1332 Adipokinetic Hormone II from Locusta migratoria 5 mg 252.1 Neuropeptide found in Locusta migratoria. ≥98% 903.9 C43H58N11O11 Ambient -20°C Soluble in water. Siegert K, Morgan P, Mordue W. Primary structures of locust adipokinetic hormones II. Biol Chem Hoppe Seyler. 1985 Aug;366(8):723-7. PMID: 4063072. Not dangerous goods.

LKT A1333 Adipokinetic Hormone II from Schistocera gregaria 1 mg 83.9 Neuropeptide found in Schistocera gregaria. ≥95% 934.02 C44H60N11O12 Ambient -20°C Soluble in water. Siegert K, Morgan P, Mordue W. Primary structures of locust adipokinetic hormones II. Biol Chem Hoppe Seyler. 1985 Aug;366(8):723-7. PMID: 4063072. Not dangerous goods.

LKT A1333 Adipokinetic Hormone II from Schistocera gregaria 2 mg 144 Neuropeptide found in Schistocera gregaria. ≥95% 934.02 C44H60N11O12 Ambient -20°C Soluble in water. Siegert K, Morgan P, Mordue W. Primary structures of locust adipokinetic hormones II. Biol Chem Hoppe Seyler. 1985 Aug;366(8):723-7. PMID: 4063072. Not dangerous goods.

LKT A1333 Adipokinetic Hormone II from Schistocera gregaria 5 mg 252.1 Neuropeptide found in Schistocera gregaria. ≥95% 934.02 C44H60N11O12 Ambient -20°C Soluble in water. Siegert K, Morgan P, Mordue W. Primary structures of locust adipokinetic hormones II. Biol Chem Hoppe Seyler. 1985 Aug;366(8):723-7. PMID: 4063072. Not dangerous goods.

LKT A1368 Adrenomedullin (1-52), human 0.5 mg 756.2 Endogenous peptide hormone, involved in cell growth and differentiation; CLR-RAMP2/3 agonist. ≥95% 6028.9 C264H406N80O77S3 Ambient -20°C "Larráyoz IM, Martínez-Herrero S, Ochoa-Callejero L, et al. Is the cytoskeleton an intracellular receptor for adrenomedullin and PAMP? Curr Protein Pept Sci. 2013 Aug;14(5):429-43. PMID: 23745706.

 

Chang CL, Hsu SY. Roles of CLR/RAMP receptor signaling in reproduction and development. Curr Protein Pept Sci. 2013 Aug;14(5):393-406. PMID: 23745703.

 

Shindo T, Sakurai T, Kamiyoshi A, et al. Regulation of adrenomedullin and its family peptide by RAMP system--lessons from genetically engineered mice. Curr Protein Pept Sci. 2013 Aug;14(5):347-57. PMID: 23745699.

 

Larrayoz IM, Ochoa-Callejero L, García-Sanmartín J, et al. Role of adrenomedullin in the growth and differentiation of stem and progenitor cells. Int Rev Cell Mol Biol. 2012;297:175-234. PMID: 22608560.

 

Wong HK, Cheung TT, Cheung BM. Adrenomedullin and cardiovascular diseases. JRSM Cardiovasc Dis. 2012 Aug 10;1(5). PMID: 24175071.

" Not dangerous goods.

LKT A1368 Adrenomedullin (1-52), human 1 mg 1284.2 Endogenous peptide hormone, involved in cell growth and differentiation; CLR-RAMP2/3 agonist. ≥95% 6028.9 C264H406N80O77S3 Ambient -20°C "Larráyoz IM, Martínez-Herrero S, Ochoa-Callejero L, et al. Is the cytoskeleton an intracellular receptor for adrenomedullin and PAMP? Curr Protein Pept Sci. 2013 Aug;14(5):429-43. PMID: 23745706.

 

Chang CL, Hsu SY. Roles of CLR/RAMP receptor signaling in reproduction and development. Curr Protein Pept Sci. 2013 Aug;14(5):393-406. PMID: 23745703.

 

Shindo T, Sakurai T, Kamiyoshi A, et al. Regulation of adrenomedullin and its family peptide by RAMP system--lessons from genetically engineered mice. Curr Protein Pept Sci. 2013 Aug;14(5):347-57. PMID: 23745699.

 

Larrayoz IM, Ochoa-Callejero L, García-Sanmartín J, et al. Role of adrenomedullin in the growth and differentiation of stem and progenitor cells. Int Rev Cell Mol Biol. 2012;297:175-234. PMID: 22608560.

 

Wong HK, Cheung TT, Cheung BM. Adrenomedullin and cardiovascular diseases. JRSM Cardiovasc Dis. 2012 Aug 10;1(5). PMID: 24175071.

" Not dangerous goods.

LKT A1368 Adrenomedullin (1-52), human 2.5 mg 2268.3 Endogenous peptide hormone, involved in cell growth and differentiation; CLR-RAMP2/3 agonist. ≥95% 6028.9 C264H406N80O77S3 Ambient -20°C "Larráyoz IM, Martínez-Herrero S, Ochoa-Callejero L, et al. Is the cytoskeleton an intracellular receptor for adrenomedullin and PAMP? Curr Protein Pept Sci. 2013 Aug;14(5):429-43. PMID: 23745706.

 

Chang CL, Hsu SY. Roles of CLR/RAMP receptor signaling in reproduction and development. Curr Protein Pept Sci. 2013 Aug;14(5):393-406. PMID: 23745703.

 

Shindo T, Sakurai T, Kamiyoshi A, et al. Regulation of adrenomedullin and its family peptide by RAMP system--lessons from genetically engineered mice. Curr Protein Pept Sci. 2013 Aug;14(5):347-57. PMID: 23745699.

 

Larrayoz IM, Ochoa-Callejero L, García-Sanmartín J, et al. Role of adrenomedullin in the growth and differentiation of stem and progenitor cells. Int Rev Cell Mol Biol. 2012;297:175-234. PMID: 22608560.

 

Wong HK, Cheung TT, Cheung BM. Adrenomedullin and cardiovascular diseases. JRSM Cardiovasc Dis. 2012 Aug 10;1(5). PMID: 24175071.

" Not dangerous goods.

LKT A1369 Adrenomedullin (13-52), human 0.5 mg 600.1 Endogenous peptide hormone, involved in cell growth and differentiation; CLR-RAMP2/3 agonist. ≥95% 4533.17 C200H308N58O59S2 Ambient -20°C "Larráyoz IM, Martínez-Herrero S, Ochoa-Callejero L, et al. Is the cytoskeleton an intracellular receptor for adrenomedullin and PAMP? Curr Protein Pept Sci. 2013 Aug;14(5):429-43. PMID: 23745706.

 

Chang CL, Hsu SY. Roles of CLR/RAMP receptor signaling in reproduction and development. Curr Protein Pept Sci. 2013 Aug;14(5):393-406. PMID: 23745703.

 

Shindo T, Sakurai T, Kamiyoshi A, et al. Regulation of adrenomedullin and its family peptide by RAMP system--lessons from genetically engineered mice. Curr Protein Pept Sci. 2013 Aug;14(5):347-57. PMID: 23745699.

 

Larrayoz IM, Ochoa-Callejero L, García-Sanmartín J, et al. Role of adrenomedullin in the growth and differentiation of stem and progenitor cells. Int Rev Cell Mol Biol. 2012;297:175-234. PMID: 22608560.

 

Wong HK, Cheung TT, Cheung BM. Adrenomedullin and cardiovascular diseases. JRSM Cardiovasc Dis. 2012 Aug 10;1(5). PMID: 24175071.

" Not dangerous goods.

LKT A1369 Adrenomedullin (13-52), human 1 mg 1020.2 Endogenous peptide hormone, involved in cell growth and differentiation; CLR-RAMP2/3 agonist. ≥95% 4533.17 C200H308N58O59S2 Ambient -20°C "Larráyoz IM, Martínez-Herrero S, Ochoa-Callejero L, et al. Is the cytoskeleton an intracellular receptor for adrenomedullin and PAMP? Curr Protein Pept Sci. 2013 Aug;14(5):429-43. PMID: 23745706.

 

Chang CL, Hsu SY. Roles of CLR/RAMP receptor signaling in reproduction and development. Curr Protein Pept Sci. 2013 Aug;14(5):393-406. PMID: 23745703.

 

Shindo T, Sakurai T, Kamiyoshi A, et al. Regulation of adrenomedullin and its family peptide by RAMP system--lessons from genetically engineered mice. Curr Protein Pept Sci. 2013 Aug;14(5):347-57. PMID: 23745699.

 

Larrayoz IM, Ochoa-Callejero L, García-Sanmartín J, et al. Role of adrenomedullin in the growth and differentiation of stem and progenitor cells. Int Rev Cell Mol Biol. 2012;297:175-234. PMID: 22608560.

 

Wong HK, Cheung TT, Cheung BM. Adrenomedullin and cardiovascular diseases. JRSM Cardiovasc Dis. 2012 Aug 10;1(5). PMID: 24175071.

" Not dangerous goods.

LKT A1369 Adrenomedullin (13-52), human 2.5 mg 1800.2 Endogenous peptide hormone, involved in cell growth and differentiation; CLR-RAMP2/3 agonist. ≥95% 4533.17 C200H308N58O59S2 Ambient -20°C "Larráyoz IM, Martínez-Herrero S, Ochoa-Callejero L, et al. Is the cytoskeleton an intracellular receptor for adrenomedullin and PAMP? Curr Protein Pept Sci. 2013 Aug;14(5):429-43. PMID: 23745706.

 

Chang CL, Hsu SY. Roles of CLR/RAMP receptor signaling in reproduction and development. Curr Protein Pept Sci. 2013 Aug;14(5):393-406. PMID: 23745703.

 

Shindo T, Sakurai T, Kamiyoshi A, et al. Regulation of adrenomedullin and its family peptide by RAMP system--lessons from genetically engineered mice. Curr Protein Pept Sci. 2013 Aug;14(5):347-57. PMID: 23745699.

 

Larrayoz IM, Ochoa-Callejero L, García-Sanmartín J, et al. Role of adrenomedullin in the growth and differentiation of stem and progenitor cells. Int Rev Cell Mol Biol. 2012;297:175-234. PMID: 22608560.

 

Wong HK, Cheung TT, Cheung BM. Adrenomedullin and cardiovascular diseases. JRSM Cardiovasc Dis. 2012 Aug 10;1(5). PMID: 24175071.

" Not dangerous goods.

LKT A1370 Adrenomedullin (22-52), human 0.5 mg 359.9 Endogenous peptide hormone, involved in cell growth and differentiation; CLR-RAMP2/3 agonist. ≥95% 3576.06 C159H252N46O48 Ambient -20°C "Larráyoz IM, Martínez-Herrero S, Ochoa-Callejero L, et al. Is the cytoskeleton an intracellular receptor for adrenomedullin and PAMP? Curr Protein Pept Sci. 2013 Aug;14(5):429-43. PMID: 23745706.

 

Chang CL, Hsu SY. Roles of CLR/RAMP receptor signaling in reproduction and development. Curr Protein Pept Sci. 2013 Aug;14(5):393-406. PMID: 23745703.

 

Shindo T, Sakurai T, Kamiyoshi A, et al. Regulation of adrenomedullin and its family peptide by RAMP system--lessons from genetically engineered mice. Curr Protein Pept Sci. 2013 Aug;14(5):347-57. PMID: 23745699.

 

Larrayoz IM, Ochoa-Callejero L, García-Sanmartín J, et al. Role of adrenomedullin in the growth and differentiation of stem and progenitor cells. Int Rev Cell Mol Biol. 2012;297:175-234. PMID: 22608560.

 

Wong HK, Cheung TT, Cheung BM. Adrenomedullin and cardiovascular diseases. JRSM Cardiovasc Dis. 2012 Aug 10;1(5). PMID: 24175071.

" Not dangerous goods.

LKT A1370 Adrenomedullin (22-52), human 1 mg 612.4 Endogenous peptide hormone, involved in cell growth and differentiation; CLR-RAMP2/3 agonist. ≥95% 3576.06 C159H252N46O48 Ambient -20°C "Larráyoz IM, Martínez-Herrero S, Ochoa-Callejero L, et al. Is the cytoskeleton an intracellular receptor for adrenomedullin and PAMP? Curr Protein Pept Sci. 2013 Aug;14(5):429-43. PMID: 23745706.

 

Chang CL, Hsu SY. Roles of CLR/RAMP receptor signaling in reproduction and development. Curr Protein Pept Sci. 2013 Aug;14(5):393-406. PMID: 23745703.

 

Shindo T, Sakurai T, Kamiyoshi A, et al. Regulation of adrenomedullin and its family peptide by RAMP system--lessons from genetically engineered mice. Curr Protein Pept Sci. 2013 Aug;14(5):347-57. PMID: 23745699.

 

Larrayoz IM, Ochoa-Callejero L, García-Sanmartín J, et al. Role of adrenomedullin in the growth and differentiation of stem and progenitor cells. Int Rev Cell Mol Biol. 2012;297:175-234. PMID: 22608560.

 

Wong HK, Cheung TT, Cheung BM. Adrenomedullin and cardiovascular diseases. JRSM Cardiovasc Dis. 2012 Aug 10;1(5). PMID: 24175071.

" Not dangerous goods.

LKT A1370 Adrenomedullin (22-52), human 2.5 mg 1080.1 Endogenous peptide hormone, involved in cell growth and differentiation; CLR-RAMP2/3 agonist. ≥95% 3576.06 C159H252N46O48 Ambient -20°C "Larráyoz IM, Martínez-Herrero S, Ochoa-Callejero L, et al. Is the cytoskeleton an intracellular receptor for adrenomedullin and PAMP? Curr Protein Pept Sci. 2013 Aug;14(5):429-43. PMID: 23745706.

 

Chang CL, Hsu SY. Roles of CLR/RAMP receptor signaling in reproduction and development. Curr Protein Pept Sci. 2013 Aug;14(5):393-406. PMID: 23745703.

 

Shindo T, Sakurai T, Kamiyoshi A, et al. Regulation of adrenomedullin and its family peptide by RAMP system--lessons from genetically engineered mice. Curr Protein Pept Sci. 2013 Aug;14(5):347-57. PMID: 23745699.

 

Larrayoz IM, Ochoa-Callejero L, García-Sanmartín J, et al. Role of adrenomedullin in the growth and differentiation of stem and progenitor cells. Int Rev Cell Mol Biol. 2012;297:175-234. PMID: 22608560.

 

Wong HK, Cheung TT, Cheung BM. Adrenomedullin and cardiovascular diseases. JRSM Cardiovasc Dis. 2012 Aug 10;1(5). PMID: 24175071.

" Not dangerous goods.

LKT A1371 Adrenorphin 1 mg 72.1 Endogenous opioid peptide; μOR and κOR agonist. Metorphamide ≥95% 984.2 C44H69N15O9S CC(C)C(C(=O)N)NC(=O)C(CCCN=C(N)N)NC(=O)C(CCCN=C(N)N)NC(=O)C(CCSC)NC(=O)C(CC1=CC=CC=C1)NC(=O)CNC(=O)CNC(=O)C(CC2=CC=C(C=C2)O)N Ambient -20°C "Yanase T, Nawata H, Kato K,et al. Studies on adrenorphin in pheochromocytoma. J Clin Endocrinol Metab. 1987 Apr;64(4):692-7. PMID: 3818899.

 

Xu SF, Lu WX, Zhou KR, et al. The analgesic and respiratory depressant actions of metorphamide in mice and rabbits. Neuropeptides. 1985 Apr;6(2):121-31. PMID: 4000426.

 

Dray A, Davis TP. The proenkephalin A fragment metorphamide shows supraspinal and spinal opioid activity in vivo. Peptides. 1985 Mar-Apr;6(2):217-21. PMID: 3839922.

 

Weber E, Esch FS, Böhlen P, et al. Metorphamide: isolation, structure, and biologic activity of an amidated opioid octapeptide from bovine brain. Proc Natl Acad Sci U S A. 1983 Dec;80(23):7362-6. PMID: 6316361.

" Not dangerous goods.

LKT A1371 Adrenorphin 2 mg 123.1 Endogenous opioid peptide; μOR and κOR agonist. Metorphamide ≥95% 984.2 C44H69N15O9S CC(C)C(C(=O)N)NC(=O)C(CCCN=C(N)N)NC(=O)C(CCCN=C(N)N)NC(=O)C(CCSC)NC(=O)C(CC1=CC=CC=C1)NC(=O)CNC(=O)CNC(=O)C(CC2=CC=C(C=C2)O)N Ambient -20°C "Yanase T, Nawata H, Kato K,et al. Studies on adrenorphin in pheochromocytoma. J Clin Endocrinol Metab. 1987 Apr;64(4):692-7. PMID: 3818899.

 

Xu SF, Lu WX, Zhou KR, et al. The analgesic and respiratory depressant actions of metorphamide in mice and rabbits. Neuropeptides. 1985 Apr;6(2):121-31. PMID: 4000426.

 

Dray A, Davis TP. The proenkephalin A fragment metorphamide shows supraspinal and spinal opioid activity in vivo. Peptides. 1985 Mar-Apr;6(2):217-21. PMID: 3839922.

 

Weber E, Esch FS, Böhlen P, et al. Metorphamide: isolation, structure, and biologic activity of an amidated opioid octapeptide from bovine brain. Proc Natl Acad Sci U S A. 1983 Dec;80(23):7362-6. PMID: 6316361.

" Not dangerous goods.

LKT A1371 Adrenorphin 5 mg 216.1 Endogenous opioid peptide; μOR and κOR agonist. Metorphamide ≥95% 984.2 C44H69N15O9S CC(C)C(C(=O)N)NC(=O)C(CCCN=C(N)N)NC(=O)C(CCCN=C(N)N)NC(=O)C(CCSC)NC(=O)C(CC1=CC=CC=C1)NC(=O)CNC(=O)CNC(=O)C(CC2=CC=C(C=C2)O)N Ambient -20°C "Yanase T, Nawata H, Kato K,et al. Studies on adrenorphin in pheochromocytoma. J Clin Endocrinol Metab. 1987 Apr;64(4):692-7. PMID: 3818899.

 

Xu SF, Lu WX, Zhou KR, et al. The analgesic and respiratory depressant actions of metorphamide in mice and rabbits. Neuropeptides. 1985 Apr;6(2):121-31. PMID: 4000426.

 

Dray A, Davis TP. The proenkephalin A fragment metorphamide shows supraspinal and spinal opioid activity in vivo. Peptides. 1985 Mar-Apr;6(2):217-21. PMID: 3839922.

 

Weber E, Esch FS, Böhlen P, et al. Metorphamide: isolation, structure, and biologic activity of an amidated opioid octapeptide from bovine brain. Proc Natl Acad Sci U S A. 1983 Dec;80(23):7362-6. PMID: 6316361.

" Not dangerous goods.

LKT A2046 Aflatoxin B2 1 mg 115.8 Mycotoxin produced by species of Aspergillus; DNA synthesis inhibitor. 7220-81-7 ≥98% 314.229 C17H14O6 COC1=C2C3=C(C(=O)CC3)C(=O)OC2=C4C5CCOC5OC4=C1 Ambient 4°C Soluble in methanol, DMSO "Miliţă NM, Mihăescu G, Chifiriuc C. Aflatoxins--health risk factors. Bacteriol Virusol Parazitol Epidemiol. 2010 Jan-Mar;55(1):19-24. PMID: 21038701.

 

Gabal MA, Hegazi SA, Hassanin N. Aflatoxin production by Aspergillus flavus field isolates. Vet Hum Toxicol. 1994 Dec;36(6):519-21. PMID: 7900269.

 

Dutton MF, Ehrlich K, Bennett JW. Biosynthetic relationship among aflatoxins B1, B2, M1, and M2. Appl Environ Microbiol. 1985 Jun;49(6):1392-5. PMID: 3925881.

" Carc., T+ "UN number: 3462     Class: 6.1     Packing Group: I

Proper shipping name: Toxins, extracted from living sources, solid, n.o.s. (Aflatoxin B2)"

LKT A2046 Aflatoxin B2 5 mg 562.7 Mycotoxin produced by species of Aspergillus; DNA synthesis inhibitor. 7220-81-7 ≥98% 314.229 C17H14O6 COC1=C2C3=C(C(=O)CC3)C(=O)OC2=C4C5CCOC5OC4=C1 Ambient 4°C Soluble in methanol, DMSO "Miliţă NM, Mihăescu G, Chifiriuc C. Aflatoxins--health risk factors. Bacteriol Virusol Parazitol Epidemiol. 2010 Jan-Mar;55(1):19-24. PMID: 21038701.

 

Gabal MA, Hegazi SA, Hassanin N. Aflatoxin production by Aspergillus flavus field isolates. Vet Hum Toxicol. 1994 Dec;36(6):519-21. PMID: 7900269.

 

Dutton MF, Ehrlich K, Bennett JW. Biosynthetic relationship among aflatoxins B1, B2, M1, and M2. Appl Environ Microbiol. 1985 Jun;49(6):1392-5. PMID: 3925881.

" Carc., T+ "UN number: 3462     Class: 6.1     Packing Group: I

Proper shipping name: Toxins, extracted from living sources, solid, n.o.s. (Aflatoxin B2)"

LKT A2048 Aflatoxin G1 1 mg 131.4 Mycotoxin produced by species of Aspergillus; DNA synthesis inhibitor. 1165-39-5 ≥98% 328.27 C17H12O7 COC1=C2C3=C(C(=O)OCC3)C(=O)OC2=C4C5C=COC5OC4=C1 Ambient 4°C Soluble in methanol, DMSO "Miliţă NM, Mihăescu G, Chifiriuc C. Aflatoxins--health risk factors. Bacteriol Virusol Parazitol Epidemiol. 2010 Jan-Mar;55(1):19-24. PMID: 21038701.

 

Gabal MA, Hegazi SA, Hassanin N. Aflatoxin production by Aspergillus flavus field isolates. Vet Hum Toxicol. 1994 Dec;36(6):519-21. PMID: 7900269.

" Carc., T+ "UN number: 3462     Class:  6.1     Packing group:  I

Proper shipping name:  Toxins, extracted from living sources, solid, n.o.s. (Aflatoxin G1)

Reprotable Quantity (RQ):     Marine pollutant:  No     Poison Inhalation Hazard:  No"

LKT A2048 Aflatoxin G1 5 mg 637.6 Mycotoxin produced by species of Aspergillus; DNA synthesis inhibitor. 1165-39-5 ≥98% 328.27 C17H12O7 COC1=C2C3=C(C(=O)OCC3)C(=O)OC2=C4C5C=COC5OC4=C1 Ambient 4°C Soluble in methanol, DMSO "Miliţă NM, Mihăescu G, Chifiriuc C. Aflatoxins--health risk factors. Bacteriol Virusol Parazitol Epidemiol. 2010 Jan-Mar;55(1):19-24. PMID: 21038701.

 

Gabal MA, Hegazi SA, Hassanin N. Aflatoxin production by Aspergillus flavus field isolates. Vet Hum Toxicol. 1994 Dec;36(6):519-21. PMID: 7900269.

" Carc., T+ "UN number: 3462     Class:  6.1     Packing group:  I

Proper shipping name:  Toxins, extracted from living sources, solid, n.o.s. (Aflatoxin G1)

Reprotable Quantity (RQ):     Marine pollutant:  No     Poison Inhalation Hazard:  No"

LKT A2050 Aflatoxin G2 1 mg 315.1 Mycotoxin produced by species of Aspergillus; DNA synthesis inhibitor. 7241-98-7 ≥98% 330.29 C17H14O7 COC1=C2C3=C(C(=O)OCC3)C(=O)OC2=C4C5CCOC5OC4=C1 Ambient 4°C Soluble in methanol, DMSO "Miliţă NM, Mihăescu G, Chifiriuc C. Aflatoxins--health risk factors. Bacteriol Virusol Parazitol Epidemiol. 2010 Jan-Mar;55(1):19-24. PMID: 21038701.

 

Gabal MA, Hegazi SA, Hassanin N. Aflatoxin production by Aspergillus flavus field isolates. Vet Hum Toxicol. 1994 Dec;36(6):519-21. PMID: 7900269.

" Carc., T+ "UN number: 3462     Class: 6.1     Packing Group: I

Proper shipping name: Toxins, extracted from living sources, solid, n.o.s. (Aflatoxin G2)"

LKT A2050 Aflatoxin G2 5 mg 1012.6 Mycotoxin produced by species of Aspergillus; DNA synthesis inhibitor. 7241-98-7 ≥98% 330.29 C17H14O7 COC1=C2C3=C(C(=O)OCC3)C(=O)OC2=C4C5CCOC5OC4=C1 Ambient 4°C Soluble in methanol, DMSO "Miliţă NM, Mihăescu G, Chifiriuc C. Aflatoxins--health risk factors. Bacteriol Virusol Parazitol Epidemiol. 2010 Jan-Mar;55(1):19-24. PMID: 21038701.

 

Gabal MA, Hegazi SA, Hassanin N. Aflatoxin production by Aspergillus flavus field isolates. Vet Hum Toxicol. 1994 Dec;36(6):519-21. PMID: 7900269.

" Carc., T+ "UN number: 3462     Class: 6.1     Packing Group: I

Proper shipping name: Toxins, extracted from living sources, solid, n.o.s. (Aflatoxin G2)"

LKT A2052 Aflatoxin M1 100 µg 122.3 Mycotoxin produced by species of Aspergillus; DNA synthesis inhibitor. 6795-23-9 ≥98% 328.27 C17H12O7 COC1=C2C3=C(C(=O)CC3)C(=O)OC2=C4C(=C1)OC5C4(C=CO5)O Ambient 4°C Soluble in methanol, DMSO "Bianco G, Russo R, Marzocco S, et al. Modulation of macrophage activity by aflatoxins B1 and B2 and their metabolites aflatoxins M1 and M2. Toxicon. 2012 May;59(6):644-50. PMID: 22402176.

 

Dutton MF, Ehrlich K, Bennett JW. Biosynthetic relationship among aflatoxins B1, B2, M1, and M2. Appl Environ Microbiol. 1985 Jun;49(6):1392-5. PMID: 3925881.

" Carc. T+ "UN number: 3462     Class: 6.1     Packing group: I

Proper shipping name: Toxins, extracted from living sources, solid, n.o.s. (Aflatoxin M1)

Poison Inhalation Hazard: No"

LKT A2052 Aflatoxin M1 1 mg 725.7 Mycotoxin produced by species of Aspergillus; DNA synthesis inhibitor. 6795-23-9 ≥98% 328.27 C17H12O7 COC1=C2C3=C(C(=O)CC3)C(=O)OC2=C4C(=C1)OC5C4(C=CO5)O Ambient 4°C Soluble in methanol, DMSO "Bianco G, Russo R, Marzocco S, et al. Modulation of macrophage activity by aflatoxins B1 and B2 and their metabolites aflatoxins M1 and M2. Toxicon. 2012 May;59(6):644-50. PMID: 22402176.

 

Dutton MF, Ehrlich K, Bennett JW. Biosynthetic relationship among aflatoxins B1, B2, M1, and M2. Appl Environ Microbiol. 1985 Jun;49(6):1392-5. PMID: 3925881.

" Carc. T+ "UN number: 3462     Class: 6.1     Packing group: I

Proper shipping name: Toxins, extracted from living sources, solid, n.o.s. (Aflatoxin M1)

Poison Inhalation Hazard: No"

LKT A2054 Aflatoxin M2 100 µg 393.2 Mycotoxin produced by species of Aspergillus; DNA synthesis inhibitor. 6885-57-0 ≥98% 330.29 C17H14O7 COC1=C2C3=C(C(=O)CC3)C(=O)OC2=C4C(=C1)OC5C4(CCO5)O Ambient 4°C DMSO, Ethanol, petrol ether. Not soluble in water "Bianco G, Russo R, Marzocco S, et al. Modulation of macrophage activity by aflatoxins B1 and B2 and their metabolites aflatoxins M1 and M2. Toxicon. 2012 May;59(6):644-50. PMID: 22402176.

 

Dutton MF, Ehrlich K, Bennett JW. Biosynthetic relationship among aflatoxins B1, B2, M1, and M2. Appl Environ Microbiol. 1985 Jun;49(6):1392-5. PMID: 3925881.

" Carc., T+ "UN number: 3462     Class: 6.1     Packing group: I

Proper shipping name: Toxins, extracted from living sources, solid, n.o.s. (Aflatoxin M2)

Poison Inhalation Hazard: No"

LKT A2054 Aflatoxin M2 1 mg 2241.9 Mycotoxin produced by species of Aspergillus; DNA synthesis inhibitor. 6885-57-0 ≥98% 330.29 C17H14O7 COC1=C2C3=C(C(=O)CC3)C(=O)OC2=C4C(=C1)OC5C4(CCO5)O Ambient 4°C DMSO, Ethanol, petrol ether. Not soluble in water "Bianco G, Russo R, Marzocco S, et al. Modulation of macrophage activity by aflatoxins B1 and B2 and their metabolites aflatoxins M1 and M2. Toxicon. 2012 May;59(6):644-50. PMID: 22402176.

 

Dutton MF, Ehrlich K, Bennett JW. Biosynthetic relationship among aflatoxins B1, B2, M1, and M2. Appl Environ Microbiol. 1985 Jun;49(6):1392-5. PMID: 3925881.

" Carc., T+ "UN number: 3462     Class: 6.1     Packing group: I

Proper shipping name: Toxins, extracted from living sources, solid, n.o.s. (Aflatoxin M2)

Poison Inhalation Hazard: No"

LKT A2412 AGDV 5 mg 180 Peptide fragment of fibrinogen, glycoprotein IIb/IIIa binding sequence. ≥95% 360.37 C14H24N4O7 Ambient -20°C "Srokowski EM, Woodhouse KA. Evaluation of the bulk platelet response and fibrinogen interaction to elastin-like polypeptide coatings. J Biomed Mater Res A. 2014 Feb;102(2):540-51. PMID: 23505204.

 

Podolnikova NP, Gorkun OV, Loreth RM, et al. A cluster of basic amino acid residues in the gamma370-381 sequence of fibrinogen comprises a binding site for platelet integrin alpha(IIb)beta3 (glycoprotein IIb/IIIa). Biochemistry. 2005 Dec 27;44(51):16920-30. PMID: 16363805.

 

Liu Q, Rooney MM, Kasirer-Friede A, et al. Role of the gamma chain Ala-Gly-Asp-Val and Aalpha chain Arg-Gly-Asp-Ser sites of fibrinogen in coaggregation of platelets and fibrinogen-coated beads. Biochim Biophys Acta. 1998 Jun 11;1385(1):33-42. PMID: 9630497.

"

LKT A2412 AGDV 10 mg 306.1 Peptide fragment of fibrinogen, glycoprotein IIb/IIIa binding sequence. ≥95% 360.37 C14H24N4O7 Ambient -20°C "Srokowski EM, Woodhouse KA. Evaluation of the bulk platelet response and fibrinogen interaction to elastin-like polypeptide coatings. J Biomed Mater Res A. 2014 Feb;102(2):540-51. PMID: 23505204.

 

Podolnikova NP, Gorkun OV, Loreth RM, et al. A cluster of basic amino acid residues in the gamma370-381 sequence of fibrinogen comprises a binding site for platelet integrin alpha(IIb)beta3 (glycoprotein IIb/IIIa). Biochemistry. 2005 Dec 27;44(51):16920-30. PMID: 16363805.

 

Liu Q, Rooney MM, Kasirer-Friede A, et al. Role of the gamma chain Ala-Gly-Asp-Val and Aalpha chain Arg-Gly-Asp-Ser sites of fibrinogen in coaggregation of platelets and fibrinogen-coated beads. Biochim Biophys Acta. 1998 Jun 11;1385(1):33-42. PMID: 9630497.

"

LKT A2412 AGDV 25 mg 540 Peptide fragment of fibrinogen, glycoprotein IIb/IIIa binding sequence. ≥95% 360.37 C14H24N4O7 Ambient -20°C "Srokowski EM, Woodhouse KA. Evaluation of the bulk platelet response and fibrinogen interaction to elastin-like polypeptide coatings. J Biomed Mater Res A. 2014 Feb;102(2):540-51. PMID: 23505204.

 

Podolnikova NP, Gorkun OV, Loreth RM, et al. A cluster of basic amino acid residues in the gamma370-381 sequence of fibrinogen comprises a binding site for platelet integrin alpha(IIb)beta3 (glycoprotein IIb/IIIa). Biochemistry. 2005 Dec 27;44(51):16920-30. PMID: 16363805.

 

Liu Q, Rooney MM, Kasirer-Friede A, et al. Role of the gamma chain Ala-Gly-Asp-Val and Aalpha chain Arg-Gly-Asp-Ser sites of fibrinogen in coaggregation of platelets and fibrinogen-coated beads. Biochim Biophys Acta. 1998 Jun 11;1385(1):33-42. PMID: 9630497.

"

LKT A3212 3′-Azido-3′-deoxythymidine 25 mg 47.6 Nucleoside (thymidine) analog; DNA chain terminator. 1-[4-azido-5-(hydroxymethyl)oxolan-2-yl]-5-methyl- pyrimidine-2,4-dione AZT; Azidothymidine; Zidovudine; ZDV; ZVD 30516-87-1 ≥98% 267.24 C10H13N5O4 CC1=CN(C(=O)NC1=O)C2CC(C(O2)CO)N=[N+]=[N-] Ambient 4°C Soluble in water (50mg/mL). "Banerjee A, Abdelmegeed MA, Jang S, et al. Zidovudine (AZT) and hepatic lipid accumulation: implication of inflammation, oxidative and endoplasmic reticulum stress mediators. PLoS One. 2013 Oct 11;8(10):e76850. PMID: 24146933.

 

Parker WB, White EL, Shaddix SC, et al. Mechanism of inhibition of human immunodeficiency virus type 1 reverse transcriptase and human DNA polymerases alpha, beta, and gamma by the 5'-triphosphates of carbovir, 3'-azido-3'-deoxythymidine, 2',3'-dideoxyguanosine and 3'-deoxythymidine. A novel RNA template for the evaluation of antiretroviral drugs. J Biol Chem. 1991 Jan 25;266(3):1754-62. PMID: 1703154.

 

Furman PA, Fyfe JA, St Clair MH, et al. Phosphorylation of 3'-azido-3'-deoxythymidine and selective interaction of the 5'-triphosphate with human immunodeficiency virus reverse transcriptase. Proc Natl Acad Sci U S A. 1986 Nov;83(21):8333-7. PMID: 2430286.

" Carc Not dangerous goods.

LKT A3212 3′-Azido-3′-deoxythymidine 100 mg 136 Nucleoside (thymidine) analog; DNA chain terminator. 1-[4-azido-5-(hydroxymethyl)oxolan-2-yl]-5-methyl- pyrimidine-2,4-dione AZT; Azidothymidine; Zidovudine; ZDV; ZVD 30516-87-1 ≥98% 267.24 C10H13N5O4 CC1=CN(C(=O)NC1=O)C2CC(C(O2)CO)N=[N+]=[N-] Ambient 4°C Soluble in water (50mg/mL). "Banerjee A, Abdelmegeed MA, Jang S, et al. Zidovudine (AZT) and hepatic lipid accumulation: implication of inflammation, oxidative and endoplasmic reticulum stress mediators. PLoS One. 2013 Oct 11;8(10):e76850. PMID: 24146933.

 

Parker WB, White EL, Shaddix SC, et al. Mechanism of inhibition of human immunodeficiency virus type 1 reverse transcriptase and human DNA polymerases alpha, beta, and gamma by the 5'-triphosphates of carbovir, 3'-azido-3'-deoxythymidine, 2',3'-dideoxyguanosine and 3'-deoxythymidine. A novel RNA template for the evaluation of antiretroviral drugs. J Biol Chem. 1991 Jan 25;266(3):1754-62. PMID: 1703154.

 

Furman PA, Fyfe JA, St Clair MH, et al. Phosphorylation of 3'-azido-3'-deoxythymidine and selective interaction of the 5'-triphosphate with human immunodeficiency virus reverse transcriptase. Proc Natl Acad Sci U S A. 1986 Nov;83(21):8333-7. PMID: 2430286.

" Carc Not dangerous goods.

LKT A3212 3′-Azido-3′-deoxythymidine 250 mg 251.5 Nucleoside (thymidine) analog; DNA chain terminator. 1-[4-azido-5-(hydroxymethyl)oxolan-2-yl]-5-methyl- pyrimidine-2,4-dione AZT; Azidothymidine; Zidovudine; ZDV; ZVD 30516-87-1 ≥98% 267.24 C10H13N5O4 CC1=CN(C(=O)NC1=O)C2CC(C(O2)CO)N=[N+]=[N-] Ambient 4°C Soluble in water (50mg/mL). "Banerjee A, Abdelmegeed MA, Jang S, et al. Zidovudine (AZT) and hepatic lipid accumulation: implication of inflammation, oxidative and endoplasmic reticulum stress mediators. PLoS One. 2013 Oct 11;8(10):e76850. PMID: 24146933.

 

Parker WB, White EL, Shaddix SC, et al. Mechanism of inhibition of human immunodeficiency virus type 1 reverse transcriptase and human DNA polymerases alpha, beta, and gamma by the 5'-triphosphates of carbovir, 3'-azido-3'-deoxythymidine, 2',3'-dideoxyguanosine and 3'-deoxythymidine. A novel RNA template for the evaluation of antiretroviral drugs. J Biol Chem. 1991 Jan 25;266(3):1754-62. PMID: 1703154.

 

Furman PA, Fyfe JA, St Clair MH, et al. Phosphorylation of 3'-azido-3'-deoxythymidine and selective interaction of the 5'-triphosphate with human immunodeficiency virus reverse transcriptase. Proc Natl Acad Sci U S A. 1986 Nov;83(21):8333-7. PMID: 2430286.

" Carc Not dangerous goods.

LKT A3212 3′-Azido-3′-deoxythymidine 1 g 516.4 Nucleoside (thymidine) analog; DNA chain terminator. 1-[4-azido-5-(hydroxymethyl)oxolan-2-yl]-5-methyl- pyrimidine-2,4-dione AZT; Azidothymidine; Zidovudine; ZDV; ZVD 30516-87-1 ≥98% 267.24 C10H13N5O4 CC1=CN(C(=O)NC1=O)C2CC(C(O2)CO)N=[N+]=[N-] Ambient 4°C Soluble in water (50mg/mL). "Banerjee A, Abdelmegeed MA, Jang S, et al. Zidovudine (AZT) and hepatic lipid accumulation: implication of inflammation, oxidative and endoplasmic reticulum stress mediators. PLoS One. 2013 Oct 11;8(10):e76850. PMID: 24146933.

 

Parker WB, White EL, Shaddix SC, et al. Mechanism of inhibition of human immunodeficiency virus type 1 reverse transcriptase and human DNA polymerases alpha, beta, and gamma by the 5'-triphosphates of carbovir, 3'-azido-3'-deoxythymidine, 2',3'-dideoxyguanosine and 3'-deoxythymidine. A novel RNA template for the evaluation of antiretroviral drugs. J Biol Chem. 1991 Jan 25;266(3):1754-62. PMID: 1703154.

 

Furman PA, Fyfe JA, St Clair MH, et al. Phosphorylation of 3'-azido-3'-deoxythymidine and selective interaction of the 5'-triphosphate with human immunodeficiency virus reverse transcriptase. Proc Natl Acad Sci U S A. 1986 Nov;83(21):8333-7. PMID: 2430286.

" Carc Not dangerous goods.

LKT A4369 A-K-R-R-R-L-S-S-L-R-A 1 mg 72.1 ROCK-2 substrate. ≥95% 1313.58 C54H104N24O14 Ambient -20°C Trauger JW, Lin FF, Turner MS, et al. Kinetic mechanism for human Rho-Kinase II (ROCK-II). Biochemistry. 2002 Jul 16;41(28):8948-53. PMID: 12102637.

LKT A4369 A-K-R-R-R-L-S-S-L-R-A 2 mg 123.1 ROCK-2 substrate. ≥95% 1313.58 C54H104N24O14 Ambient -20°C Trauger JW, Lin FF, Turner MS, et al. Kinetic mechanism for human Rho-Kinase II (ROCK-II). Biochemistry. 2002 Jul 16;41(28):8948-53. PMID: 12102637.

LKT A4369 A-K-R-R-R-L-S-S-L-R-A 5 mg 216.1 ROCK-2 substrate. ≥95% 1313.58 C54H104N24O14 Ambient -20°C Trauger JW, Lin FF, Turner MS, et al. Kinetic mechanism for human Rho-Kinase II (ROCK-II). Biochemistry. 2002 Jul 16;41(28):8948-53. PMID: 12102637.

LKT A4400 Alamethicin 1 mg 63.8 Antimicrobial peptide found in Trichoderma, induces membrane pore formation. 27061-78-5 ≥95% 1964.4 C92H150N22O25 CC(C)CC(C(=O)NC(C)(C)C(=O)N1CCCC1C(=O)NC(C(C)C)C(=O)NC(C)(C)C(=O)NC(C)(C)C(=O)NC(CCC(=O)O)C(=O)NC(CCC(=O)N)C(=O)NC(CC2=CC=CC=C2)CO)NC(=O)CNC(=O)C(C)(C)NC(=O)C(C(C)C)NC(=O)C(C)(C)NC(=O)C(CCC(=O)N)NC(=O)C(C)NC(=O)C(C)(C)NC(=O)C(C)NC(=O)C(C)(C)NC(=O)C3CCCN3C(=O)C(C)(C)NC(=O)C Ambient 4°C DMSO, Methanol (20 mg/ml), Ethanol (100 mg/ml) "Krauson AJ, He J, Wimley WC. Determining the mechanism of membrane permeabilizing peptides: identification of potent, equilibrium pore-formers. Biochim Biophys Acta. 2012 Jul;1818(7):1625-32. PMID: 22365969.

 

Huang HW. Molecular mechanism of antimicrobial peptides: the origin of cooperativity. Biochim Biophys Acta. 2006 Sep;1758(9):1292-302. PMID: 16542637.

" "UN number: 3462     Class:  6.1     Packing group:  III

Proper shipping name:  Toxins, extracted from living sources, solid, n.o.s. (Alamethicin)

Marine pollutant:  No     Poison inhalation hazard:  No"

LKT A4400 Alamethicin 5 mg 258.9 Antimicrobial peptide found in Trichoderma, induces membrane pore formation. 27061-78-5 ≥95% 1964.4 C92H150N22O25 CC(C)CC(C(=O)NC(C)(C)C(=O)N1CCCC1C(=O)NC(C(C)C)C(=O)NC(C)(C)C(=O)NC(C)(C)C(=O)NC(CCC(=O)O)C(=O)NC(CCC(=O)N)C(=O)NC(CC2=CC=CC=C2)CO)NC(=O)CNC(=O)C(C)(C)NC(=O)C(C(C)C)NC(=O)C(C)(C)NC(=O)C(CCC(=O)N)NC(=O)C(C)NC(=O)C(C)(C)NC(=O)C(C)NC(=O)C(C)(C)NC(=O)C3CCCN3C(=O)C(C)(C)NC(=O)C Ambient 4°C DMSO, Methanol (20 mg/ml), Ethanol (100 mg/ml) "Krauson AJ, He J, Wimley WC. Determining the mechanism of membrane permeabilizing peptides: identification of potent, equilibrium pore-formers. Biochim Biophys Acta. 2012 Jul;1818(7):1625-32. PMID: 22365969.

 

Huang HW. Molecular mechanism of antimicrobial peptides: the origin of cooperativity. Biochim Biophys Acta. 2006 Sep;1758(9):1292-302. PMID: 16542637.

" "UN number: 3462     Class:  6.1     Packing group:  III

Proper shipping name:  Toxins, extracted from living sources, solid, n.o.s. (Alamethicin)

Marine pollutant:  No     Poison inhalation hazard:  No"

LKT A4401 ALAL 1 mg 23.9 Tetrapeptide used as a linker in drug development. ≥95% 386.5 C18H34N4O5 Ambient -20°C "Schmid B, Chung DE, Warnecke A, et al. Albumin-binding prodrugs of camptothecin and doxorubicin with an Ala-Leu-Ala-Leu-linker that are cleaved by cathepsin B: synthesis and antitumor efficacy. Bioconjug Chem. 2007 May-Jun;18(3):702-16. PMID: 17378599.

 

Mier W, Beijer B, Graham K, et al. Fluorescent somatostatin receptor probes for the intraoperative detection of tumor tissue with long-wavelength visible light. Bioorg Med Chem. 2002 Aug;10(8):2543-52. PMID: 12057643.

 

Fitzpatrick JJ, Garnett MC. Design, synthesis and in vitro testing of methotrexate carrier conjugates linked via oligopeptide spacers. Anticancer Drug Des. 1995 Jan;10(1):1-9. PMID: 7695810.

"

LKT A4401 ALAL 2 mg 42 Tetrapeptide used as a linker in drug development. ≥95% 386.5 C18H34N4O5 Ambient -20°C "Schmid B, Chung DE, Warnecke A, et al. Albumin-binding prodrugs of camptothecin and doxorubicin with an Ala-Leu-Ala-Leu-linker that are cleaved by cathepsin B: synthesis and antitumor efficacy. Bioconjug Chem. 2007 May-Jun;18(3):702-16. PMID: 17378599.

 

Mier W, Beijer B, Graham K, et al. Fluorescent somatostatin receptor probes for the intraoperative detection of tumor tissue with long-wavelength visible light. Bioorg Med Chem. 2002 Aug;10(8):2543-52. PMID: 12057643.

 

Fitzpatrick JJ, Garnett MC. Design, synthesis and in vitro testing of methotrexate carrier conjugates linked via oligopeptide spacers. Anticancer Drug Des. 1995 Jan;10(1):1-9. PMID: 7695810.

"

LKT A4401 ALAL 5 mg 72.1 Tetrapeptide used as a linker in drug development. ≥95% 386.5 C18H34N4O5 Ambient -20°C "Schmid B, Chung DE, Warnecke A, et al. Albumin-binding prodrugs of camptothecin and doxorubicin with an Ala-Leu-Ala-Leu-linker that are cleaved by cathepsin B: synthesis and antitumor efficacy. Bioconjug Chem. 2007 May-Jun;18(3):702-16. PMID: 17378599.

 

Mier W, Beijer B, Graham K, et al. Fluorescent somatostatin receptor probes for the intraoperative detection of tumor tissue with long-wavelength visible light. Bioorg Med Chem. 2002 Aug;10(8):2543-52. PMID: 12057643.

 

Fitzpatrick JJ, Garnett MC. Design, synthesis and in vitro testing of methotrexate carrier conjugates linked via oligopeptide spacers. Anticancer Drug Des. 1995 Jan;10(1):1-9. PMID: 7695810.

"

LKT A4402 L-Alaninol 1 g 46.2 Amino acid alcohol. (S)-(+)-2-Amino-1-propanol 2749-11-3 ≥98% 75.11 C3H9NO CC(CO)N Hygroscopic. Ambient Ambient +17.6° Miscible in water. Landau O, Wasserman L, Deutsch AA, et al. Amino acid alcohols: growth inhibition and induction of differentiated features in melanoma cells. Cancer Lett. 1993 May 14;69(3):203-8. PMID: 8099846. Xi, C "UN number: 2735     Class: 8     Packing Group: II

Proper shipping name: Amines, liquid, corrosive, n.o.s. (L-Alaninol)"

LKT A4402 L-Alaninol 10 g 312 Amino acid alcohol. (S)-(+)-2-Amino-1-propanol 2749-11-3 ≥98% 75.11 C3H9NO CC(CO)N Hygroscopic. Ambient Ambient +17.6° Miscible in water. Landau O, Wasserman L, Deutsch AA, et al. Amino acid alcohols: growth inhibition and induction of differentiated features in melanoma cells. Cancer Lett. 1993 May 14;69(3):203-8. PMID: 8099846. Xi, C "UN number: 2735     Class: 8     Packing Group: II

Proper shipping name: Amines, liquid, corrosive, n.o.s. (L-Alaninol)"

LKT A4438 Allatostatin I 1 mg 83.9 Neuropeptide found in insects; juvenile hormone synthesis inhibitor. ≥95% 1335.54 C61H94N18O16 CC(C)CC(C(=O)N)NC(=O)CNC(=O)C(CC1=CC=CC=C1)NC(=O)CNC(=O)C(CC2=CC=C(C=C2)O)NC(=O)C(CC(C)C)NC(=O)C(CCCN=C(N)N)NC(=O)C(CCC(=O)N)NC(=O)C(C)NC(=O)CNC(=O)C(CO)NC(=O)C3CCCN3C(=O)C(C)N Ambient -20°C "Lloyd GT, Woodhead AP, Stay B. Release of neurosecretory granules within the corpus allatum in relation to the regulation of juvenile hormone synthesis in Diploptera punctata. Insect Biochem Mol Biol. 2000 Aug-Sep;30(8-9):739-46. PMID: 10876117.

 

Skinner JR, Fairbairn SE, Woodhead AP, et al. Allatostatin in hemocytes of the cockroach Diploptera punctata. Cell Tissue Res. 1997 Oct;290(1):119-28. PMID: 9377632.

" Not dangerous goods.

LKT A4438 Allatostatin I 2 mg 144 Neuropeptide found in insects; juvenile hormone synthesis inhibitor. ≥95% 1335.54 C61H94N18O16 CC(C)CC(C(=O)N)NC(=O)CNC(=O)C(CC1=CC=CC=C1)NC(=O)CNC(=O)C(CC2=CC=C(C=C2)O)NC(=O)C(CC(C)C)NC(=O)C(CCCN=C(N)N)NC(=O)C(CCC(=O)N)NC(=O)C(C)NC(=O)CNC(=O)C(CO)NC(=O)C3CCCN3C(=O)C(C)N Ambient -20°C "Lloyd GT, Woodhead AP, Stay B. Release of neurosecretory granules within the corpus allatum in relation to the regulation of juvenile hormone synthesis in Diploptera punctata. Insect Biochem Mol Biol. 2000 Aug-Sep;30(8-9):739-46. PMID: 10876117.

 

Skinner JR, Fairbairn SE, Woodhead AP, et al. Allatostatin in hemocytes of the cockroach Diploptera punctata. Cell Tissue Res. 1997 Oct;290(1):119-28. PMID: 9377632.

" Not dangerous goods.

LKT A4438 Allatostatin I 5 mg 252.1 Neuropeptide found in insects; juvenile hormone synthesis inhibitor. ≥95% 1335.54 C61H94N18O16 CC(C)CC(C(=O)N)NC(=O)CNC(=O)C(CC1=CC=CC=C1)NC(=O)CNC(=O)C(CC2=CC=C(C=C2)O)NC(=O)C(CC(C)C)NC(=O)C(CCCN=C(N)N)NC(=O)C(CCC(=O)N)NC(=O)C(C)NC(=O)CNC(=O)C(CO)NC(=O)C3CCCN3C(=O)C(C)N Ambient -20°C "Lloyd GT, Woodhead AP, Stay B. Release of neurosecretory granules within the corpus allatum in relation to the regulation of juvenile hormone synthesis in Diploptera punctata. Insect Biochem Mol Biol. 2000 Aug-Sep;30(8-9):739-46. PMID: 10876117.

 

Skinner JR, Fairbairn SE, Woodhead AP, et al. Allatostatin in hemocytes of the cockroach Diploptera punctata. Cell Tissue Res. 1997 Oct;290(1):119-28. PMID: 9377632.

" Not dangerous goods.

LKT A4440 Allicin 1 mg 273.3 Organosulfur found in garlic, binds DNA; inwardly rectifying K+ channel activator, L-type Ca2+ channel blocker. Thio-2-propene-1-sulfinic acid S-allyl ester Allylthiosulphinic acid allyl ester; Diallyl thiosulfinate 539-86-6 ≥98% 162.27 C6H10OS2 C=CCSS(=O)CC=C Extremely heat sensitive. Dry Ice -80°C Soluble in water. Miscible with alcohol, ether, benzene. "Chu YL, Ho CT, Chung JG, et al. Allicin Induces Anti-human Liver Cancer Cells through the p53 Gene Modulating Apoptosis and Autophagy. J Agric Food Chem. 2013 Oct 16;61(41):9839-9848. PMID: 24059278.

 

Tyagi G, Pradhan S, Srivastava T, et al. Nucleic acid binding properties of allicin: Spectroscopic analysis and estimation of anti-tumor potential. Biochim Biophys Acta. 2013 Sep 13;1840(1):350-356. PMID: 24041991.

 

Liu DS, Gao W, Liang ES, et al. Effects of allicin on hyperhomocysteinemia-induced experimental vascular endothelial dysfunction. Eur J Pharmacol. 2013 Aug 15;714(1-3):163-9. PMID: 23792140.

 

Ashry NA, Gameil NM, Suddek GM. Modulation of cyclophosphamide-induced early lung injury by allicin. Pharm Biol. 2013 Jun;51(6):806-11. PMID: 23675840.

 

Elkayam A, Peleg E, Grossman E, et al. Effects of allicin on cardiovascular risk factors in spontaneously hypertensive rats. Isr Med Assoc J. 2013 Mar;15(3):170-3. PMID: 23662381.

 

Huang W, Wang Y, Cao YG, et al. Antiarrhythmic effects and ionic mechanisms of allicin on myocardial injury of diabetic rats induced by streptozotocin. Naunyn Schmiedebergs Arch Pharmacol. 2013 Aug;386(8):697-704. PMID: 23604291.

 

Osman M, Adnan A, Salmah Bakar N, et al. Allicin has significant effect on autoimmune anti-islet cell antibodies in type 1 diabetic rats. Pol J Pathol. 2012 Dec;63(4):248-54. PMID: 23359194.

 

Jesús Corral-Caridad M, Moreno I, Toraño A, et al. Effect of allicin on promastigotes and intracellular amastigotes of Leishmania donovani and L. infantum. Exp Parasitol. 2012 Dec;132(4):475-82. PMID: 22995646.

 

Li XH, Li CY, Xiang ZG, et al. Allicin ameliorates cardiac hypertrophy and fibrosis through enhancing of Nrf2 antioxidant signaling pathways. Cardiovasc Drugs Ther. 2012 Dec;26(6):457-65. PMID: 22990325.

 

Zhang L, Zhang H, Miao Y, et al. Protective effect of allicin against acrylamide-induced hepatocyte damage in vitro and in vivo. Food Chem Toxicol. 2012 Sep;50(9):3306-12. PMID: 22705327.

" T F "UN number: 1230     Class: 3 (6.1)     Packing Group: II

Proper Shipping Name: Methanol

Reportable Quantity: 5000 lbs       Marine pollutant: No         Poison Inhalation Hazard: No"

LKT A4440 Allicin 5 mg 960.8 Organosulfur found in garlic, binds DNA; inwardly rectifying K+ channel activator, L-type Ca2+ channel blocker. Thio-2-propene-1-sulfinic acid S-allyl ester Allylthiosulphinic acid allyl ester; Diallyl thiosulfinate 539-86-6 ≥98% 162.27 C6H10OS2 C=CCSS(=O)CC=C Extremely heat sensitive. Dry Ice -80°C Soluble in water. Miscible with alcohol, ether, benzene. "Chu YL, Ho CT, Chung JG, et al. Allicin Induces Anti-human Liver Cancer Cells through the p53 Gene Modulating Apoptosis and Autophagy. J Agric Food Chem. 2013 Oct 16;61(41):9839-9848. PMID: 24059278.

 

Tyagi G, Pradhan S, Srivastava T, et al. Nucleic acid binding properties of allicin: Spectroscopic analysis and estimation of anti-tumor potential. Biochim Biophys Acta. 2013 Sep 13;1840(1):350-356. PMID: 24041991.

 

Liu DS, Gao W, Liang ES, et al. Effects of allicin on hyperhomocysteinemia-induced experimental vascular endothelial dysfunction. Eur J Pharmacol. 2013 Aug 15;714(1-3):163-9. PMID: 23792140.

 

Ashry NA, Gameil NM, Suddek GM. Modulation of cyclophosphamide-induced early lung injury by allicin. Pharm Biol. 2013 Jun;51(6):806-11. PMID: 23675840.

 

Elkayam A, Peleg E, Grossman E, et al. Effects of allicin on cardiovascular risk factors in spontaneously hypertensive rats. Isr Med Assoc J. 2013 Mar;15(3):170-3. PMID: 23662381.

 

Huang W, Wang Y, Cao YG, et al. Antiarrhythmic effects and ionic mechanisms of allicin on myocardial injury of diabetic rats induced by streptozotocin. Naunyn Schmiedebergs Arch Pharmacol. 2013 Aug;386(8):697-704. PMID: 23604291.

 

Osman M, Adnan A, Salmah Bakar N, et al. Allicin has significant effect on autoimmune anti-islet cell antibodies in type 1 diabetic rats. Pol J Pathol. 2012 Dec;63(4):248-54. PMID: 23359194.

 

Jesús Corral-Caridad M, Moreno I, Toraño A, et al. Effect of allicin on promastigotes and intracellular amastigotes of Leishmania donovani and L. infantum. Exp Parasitol. 2012 Dec;132(4):475-82. PMID: 22995646.

 

Li XH, Li CY, Xiang ZG, et al. Allicin ameliorates cardiac hypertrophy and fibrosis through enhancing of Nrf2 antioxidant signaling pathways. Cardiovasc Drugs Ther. 2012 Dec;26(6):457-65. PMID: 22990325.

 

Zhang L, Zhang H, Miao Y, et al. Protective effect of allicin against acrylamide-induced hepatocyte damage in vitro and in vivo. Food Chem Toxicol. 2012 Sep;50(9):3306-12. PMID: 22705327.

" T F "UN number: 1230     Class: 3 (6.1)     Packing Group: II

Proper Shipping Name: Methanol

Reportable Quantity: 5000 lbs       Marine pollutant: No         Poison Inhalation Hazard: No"

LKT A4444 L-Alliin 100 mg 134.9 Cysteine derivative found in Allium; NMDA NR2A/2B agonist. 3-[(S)-2-Propenylsulfinyl]-L-alanine R,S-Allyl-L-cysteine sulfoxide ≥98% 177.22 C6H11NO3S C=CCS(=O)CC(C(=O)O)N Ambient -20°C Soluble in water.  Practically insoluble in ethanol, chloroform, acetone, ether, and benzene. "Ieong Tou W, Chang SS, Wu D, et al. Molecular level activation insights from a NR2A/NR2B agonist. J Biomol Struct Dyn. 2014;32(5):683-93. PMID: 23600691.

 

Quintero-Fabián S, Ortuño-Sahagún D, Vázquez-Carrera M, et al. Alliin, a garlic (Allium sativum) compound, prevents LPS-induced inflammation in 3T3-L1 adipocytes. Mediators Inflamm. 2013;2013:381815. PMID: 24453416.

 

Nasim SA, Dhir B, Kapoor R, et al. Alliin obtained from leaf extract of garlic grown under in situ conditions possess higher therapeutic potency as analyzed in alloxan-induced diabetic rats. Pharm Biol. 2011 Apr;49(4):416-21. PMID: 21391887.

 

Sangeetha T, Darlin Quine S. Preventive effect of S-allyl cysteine sulphoxide (Alliin) on mitochondrial dysfunction in normal and isoproterenol induced cardiotoxicity in male Wistar rats: a histopathological study. Mol Cell Biochem. 2009 Aug;328(1-2):1-8. PMID: 19262997.

 

Mousa AS, Mousa SA. Anti-angiogenesis efficacy of the garlic ingredient alliin and antioxidants: role of nitric oxide and p53. Nutr Cancer. 2005;53(1):104-10. PMID: 16351512.

" Not dangerous goods.

LKT A4444 L-Alliin 500 mg 554.8 Cysteine derivative found in Allium; NMDA NR2A/2B agonist. 3-[(S)-2-Propenylsulfinyl]-L-alanine R,S-Allyl-L-cysteine sulfoxide ≥98% 177.22 C6H11NO3S C=CCS(=O)CC(C(=O)O)N Ambient -20°C Soluble in water.  Practically insoluble in ethanol, chloroform, acetone, ether, and benzene. "Ieong Tou W, Chang SS, Wu D, et al. Molecular level activation insights from a NR2A/NR2B agonist. J Biomol Struct Dyn. 2014;32(5):683-93. PMID: 23600691.

 

Quintero-Fabián S, Ortuño-Sahagún D, Vázquez-Carrera M, et al. Alliin, a garlic (Allium sativum) compound, prevents LPS-induced inflammation in 3T3-L1 adipocytes. Mediators Inflamm. 2013;2013:381815. PMID: 24453416.

 

Nasim SA, Dhir B, Kapoor R, et al. Alliin obtained from leaf extract of garlic grown under in situ conditions possess higher therapeutic potency as analyzed in alloxan-induced diabetic rats. Pharm Biol. 2011 Apr;49(4):416-21. PMID: 21391887.

 

Sangeetha T, Darlin Quine S. Preventive effect of S-allyl cysteine sulphoxide (Alliin) on mitochondrial dysfunction in normal and isoproterenol induced cardiotoxicity in male Wistar rats: a histopathological study. Mol Cell Biochem. 2009 Aug;328(1-2):1-8. PMID: 19262997.

 

Mousa AS, Mousa SA. Anti-angiogenesis efficacy of the garlic ingredient alliin and antioxidants: role of nitric oxide and p53. Nutr Cancer. 2005;53(1):104-10. PMID: 16351512.

" Not dangerous goods.

LKT A4444 L-Alliin 1 g 893.3 Cysteine derivative found in Allium; NMDA NR2A/2B agonist. 3-[(S)-2-Propenylsulfinyl]-L-alanine R,S-Allyl-L-cysteine sulfoxide ≥98% 177.22 C6H11NO3S C=CCS(=O)CC(C(=O)O)N Ambient -20°C Soluble in water.  Practically insoluble in ethanol, chloroform, acetone, ether, and benzene. "Ieong Tou W, Chang SS, Wu D, et al. Molecular level activation insights from a NR2A/NR2B agonist. J Biomol Struct Dyn. 2014;32(5):683-93. PMID: 23600691.

 

Quintero-Fabián S, Ortuño-Sahagún D, Vázquez-Carrera M, et al. Alliin, a garlic (Allium sativum) compound, prevents LPS-induced inflammation in 3T3-L1 adipocytes. Mediators Inflamm. 2013;2013:381815. PMID: 24453416.

 

Nasim SA, Dhir B, Kapoor R, et al. Alliin obtained from leaf extract of garlic grown under in situ conditions possess higher therapeutic potency as analyzed in alloxan-induced diabetic rats. Pharm Biol. 2011 Apr;49(4):416-21. PMID: 21391887.

 

Sangeetha T, Darlin Quine S. Preventive effect of S-allyl cysteine sulphoxide (Alliin) on mitochondrial dysfunction in normal and isoproterenol induced cardiotoxicity in male Wistar rats: a histopathological study. Mol Cell Biochem. 2009 Aug;328(1-2):1-8. PMID: 19262997.

 

Mousa AS, Mousa SA. Anti-angiogenesis efficacy of the garlic ingredient alliin and antioxidants: role of nitric oxide and p53. Nutr Cancer. 2005;53(1):104-10. PMID: 16351512.

" Not dangerous goods.

LKT A4498 Alytesin 1 mg 60 Antimicrobial peptide found in amphibians. 31078-12-3 ≥95% 1535.8 C68H106N22O17S CC(C)CC(C(=O)NCC(=O)NC(C(C)O)C(=O)NC(CCC(=O)N)C(=O)NC(CC1=CNC2=CC=CC=C21)C(=O)NC(C)C(=O)NC(C(C)C)C(=O)NCC(=O)NC(CC3=CN=CN3)C(=O)NC(CC(C)C)C(=O)NC(CCSC)C(=O)N)NC(=O)C(CCCN=C(N)N)NC(=O)CNC(=O)C4CCC(=O)N4 Ambient -20°C "König E, Zhou M, Wang L, et al. Antimicrobial peptides and alytesin are co-secreted from the venom of the Midwife toad, Alytes maurus (Alytidae, Anura): implications for the evolution of frog skin defensive secretions. Toxicon. 2012 Nov;60(6):967-81. PMID: 22800568

 

Cline MA, Fouse DN, Prall BC. Central and peripheral alytesin cause short-term anorexigenic effects in neonatal chicks. Neuropeptides. 2008 Jun;42(3):283-91. PMID: 18384875.

 

Guglietta A, Strunk CL, Irons BJ, et al. Central neuromodulation of gastric acid secretion by bombesin-like peptides. Peptides. 1985;6 Suppl 3:75-81. Erratum in: Peptides 1987 May-Jun;8(3):579.  PMID: 3841693.

" Not dangerous goods.

LKT A4498 Alytesin 2 mg 101.9 Antimicrobial peptide found in amphibians. 31078-12-3 ≥95% 1535.8 C68H106N22O17S CC(C)CC(C(=O)NCC(=O)NC(C(C)O)C(=O)NC(CCC(=O)N)C(=O)NC(CC1=CNC2=CC=CC=C21)C(=O)NC(C)C(=O)NC(C(C)C)C(=O)NCC(=O)NC(CC3=CN=CN3)C(=O)NC(CC(C)C)C(=O)NC(CCSC)C(=O)N)NC(=O)C(CCCN=C(N)N)NC(=O)CNC(=O)C4CCC(=O)N4 Ambient -20°C "König E, Zhou M, Wang L, et al. Antimicrobial peptides and alytesin are co-secreted from the venom of the Midwife toad, Alytes maurus (Alytidae, Anura): implications for the evolution of frog skin defensive secretions. Toxicon. 2012 Nov;60(6):967-81. PMID: 22800568

 

Cline MA, Fouse DN, Prall BC. Central and peripheral alytesin cause short-term anorexigenic effects in neonatal chicks. Neuropeptides. 2008 Jun;42(3):283-91. PMID: 18384875.

 

Guglietta A, Strunk CL, Irons BJ, et al. Central neuromodulation of gastric acid secretion by bombesin-like peptides. Peptides. 1985;6 Suppl 3:75-81. Erratum in: Peptides 1987 May-Jun;8(3):579.  PMID: 3841693.

" Not dangerous goods.

LKT A4498 Alytesin 5 mg 180 Antimicrobial peptide found in amphibians. 31078-12-3 ≥95% 1535.8 C68H106N22O17S CC(C)CC(C(=O)NCC(=O)NC(C(C)O)C(=O)NC(CCC(=O)N)C(=O)NC(CC1=CNC2=CC=CC=C21)C(=O)NC(C)C(=O)NC(C(C)C)C(=O)NCC(=O)NC(CC3=CN=CN3)C(=O)NC(CC(C)C)C(=O)NC(CCSC)C(=O)N)NC(=O)C(CCCN=C(N)N)NC(=O)CNC(=O)C4CCC(=O)N4 Ambient -20°C "König E, Zhou M, Wang L, et al. Antimicrobial peptides and alytesin are co-secreted from the venom of the Midwife toad, Alytes maurus (Alytidae, Anura): implications for the evolution of frog skin defensive secretions. Toxicon. 2012 Nov;60(6):967-81. PMID: 22800568

 

Cline MA, Fouse DN, Prall BC. Central and peripheral alytesin cause short-term anorexigenic effects in neonatal chicks. Neuropeptides. 2008 Jun;42(3):283-91. PMID: 18384875.

 

Guglietta A, Strunk CL, Irons BJ, et al. Central neuromodulation of gastric acid secretion by bombesin-like peptides. Peptides. 1985;6 Suppl 3:75-81. Erratum in: Peptides 1987 May-Jun;8(3):579.  PMID: 3841693.

" Not dangerous goods.

LKT A4515 Alendronate Monosodium Trihydrate 100 mg 85.4 Bisphosphonate. 4-Amino-1-hydroxybutylidine-1,1-bisphosphate Alendronic acid; ABDP 121268-17-5 ≥98% 325.08 C4H12NNaO7P2 3 H20 C(CC(O)(P(=O)(O)O)P(=O)(O)[O-])CN.[Na+] Ambient Ambient Soluble in water (10 mg/mL). PBS 0.25 mg/mL. DMSO <1 mg/mL. "Tsubaki M, Komai M, Itoh T, et al. Nitrogen-containing bisphosphonates inhibit RANKL- and M-CSF-induced osteoclast formation through the inhibition of ERK1/2 and Akt activation. J Biomed Sci. 2014 Feb 3;21:10. PMID: 24490900.

 

Sasaki O, Imamura M, Yamazumi Y, et al. Alendronate attenuates eosinophilic airway inflammation associated with suppression of Th2 cytokines, Th17 cytokines, and eotaxin-2. J Immunol. 2013 Sep 15;191(6):2879-89. PMID: 23935198.

 

Gutman D, Epstein-Barash H, Tsuriel M, et al. Alendronate liposomes for antitumor therapy: activation of γδ T cells and inhibition of tumor growth. Adv Exp Med Biol. 2012;733:165-79. PMID: 22101722.

 

Takahashi H, Kinbara M, Sato N, et al. Nickel allergy-promoting effects of microbial or inflammatory substances at the sensitization step in mice. Int Immunopharmacol. 2011 Oct;11(10):1534-1540. PMID: 21621645.

" XN Not dangerous goods.

LKT A4515 Alendronate Monosodium Trihydrate 500 mg 298.5 Bisphosphonate. 4-Amino-1-hydroxybutylidine-1,1-bisphosphate Alendronic acid; ABDP 121268-17-5 ≥98% 325.08 C4H12NNaO7P2 3 H20 C(CC(O)(P(=O)(O)O)P(=O)(O)[O-])CN.[Na+] Ambient Ambient Soluble in water (10 mg/mL). PBS 0.25 mg/mL. DMSO <1 mg/mL. "Tsubaki M, Komai M, Itoh T, et al. Nitrogen-containing bisphosphonates inhibit RANKL- and M-CSF-induced osteoclast formation through the inhibition of ERK1/2 and Akt activation. J Biomed Sci. 2014 Feb 3;21:10. PMID: 24490900.

 

Sasaki O, Imamura M, Yamazumi Y, et al. Alendronate attenuates eosinophilic airway inflammation associated with suppression of Th2 cytokines, Th17 cytokines, and eotaxin-2. J Immunol. 2013 Sep 15;191(6):2879-89. PMID: 23935198.

 

Gutman D, Epstein-Barash H, Tsuriel M, et al. Alendronate liposomes for antitumor therapy: activation of γδ T cells and inhibition of tumor growth. Adv Exp Med Biol. 2012;733:165-79. PMID: 22101722.

 

Takahashi H, Kinbara M, Sato N, et al. Nickel allergy-promoting effects of microbial or inflammatory substances at the sensitization step in mice. Int Immunopharmacol. 2011 Oct;11(10):1534-1540. PMID: 21621645.

" XN Not dangerous goods.

LKT A4521 Alfacalcidol 1 mg 101.9 Vitamin D analog. "1-Hydroxyvitamin D3; 1-Hydroxycholecalciferol

(1α,3β,5Z,7E)-9,10-Secocholesta-5,7,10(19)-triene-1,3-diol" 41294-56-8 ≥98% 400.64 C27H44O2 CC(C)CCCC(C)C1CCC2C1(CCCC2=CC=C3CC(CC(C3=C)O)O)C Protect from light. Ambient -20°C Soluble in THF and methanol. "Mazzaferro S, Goldsmith D, Larsson TE, et al. Vitamin D Metabolites and/or Analogs: Which D for Which Patient? Curr Vasc Pharmacol. 2014 Mar;12(2):339-49. PMID: 23713876.

 

Hara S, Kishimoto KN, Okuno H, et al. Effects of alfacalcidol on back extensor strength gained through back extensor exercise in postmenopausal women with osteoporosis. Am J Phys Med Rehabil. 2013 Feb;92(2):101-10. PMID: 23044701.

 

Chen H, Tian X, Liu X, et al. Alfacalcidol-stimulated focal bone formation on the cancellous surface and increased bone formation on the periosteal surface of the lumbar vertebrae of adult female rats. Calcif Tissue Int. 2008 Feb;82(2):127-36. PMID: 18175034. 

" T+, Xi "UN number: 2811     Class: 6.1     Packing Group: I

Proper shipping name: Toxic solid, organic, n.o.s. (Alfacalcidol)"

LKT A4521 Alfacalcidol 5 mg 421.4 Vitamin D analog. "1-Hydroxyvitamin D3; 1-Hydroxycholecalciferol

(1α,3β,5Z,7E)-9,10-Secocholesta-5,7,10(19)-triene-1,3-diol" 41294-56-8 ≥98% 400.64 C27H44O2 CC(C)CCCC(C)C1CCC2C1(CCCC2=CC=C3CC(CC(C3=C)O)O)C Protect from light. Ambient -20°C Soluble in THF and methanol. "Mazzaferro S, Goldsmith D, Larsson TE, et al. Vitamin D Metabolites and/or Analogs: Which D for Which Patient? Curr Vasc Pharmacol. 2014 Mar;12(2):339-49. PMID: 23713876.

 

Hara S, Kishimoto KN, Okuno H, et al. Effects of alfacalcidol on back extensor strength gained through back extensor exercise in postmenopausal women with osteoporosis. Am J Phys Med Rehabil. 2013 Feb;92(2):101-10. PMID: 23044701.

 

Chen H, Tian X, Liu X, et al. Alfacalcidol-stimulated focal bone formation on the cancellous surface and increased bone formation on the periosteal surface of the lumbar vertebrae of adult female rats. Calcif Tissue Int. 2008 Feb;82(2):127-36. PMID: 18175034. 

" T+, Xi "UN number: 2811     Class: 6.1     Packing Group: I

Proper shipping name: Toxic solid, organic, n.o.s. (Alfacalcidol)"

LKT A4523 Alfuzosin Hydrochloride 100 mg 125.6 α1-adrenergic antagonist. (2RS)-N-[3-[(4-Amino-6, 7-dimethoxyquinazolin-2-yl)methylamino]propyl]tetrahydrofuran-2-carboxamide hydrochloride 81403-68-1 ≥98% 425.91 C19H27N5O4 HCl CN(CCCNC(=O)C1CCCO1)C2=NC3=CC(=C(C=C3C(=N2)N)OC)OC.Cl Ambient Ambient "Lacerda AE, Kuryshev YA, Chen Y, et al. Alfuzosin delays cardiac repolarization by a novel mechanism. J Pharmacol Exp Ther. 2008 Feb;324(2):427-33. PMID: 17986649.

 

Lee M. Alfuzosin hydrochloride for the treatment of benign prostatic hyperplasia. Am J Health Syst Pharm. 2003 Jul 15;60(14):1426-39. Erratum in: Am J Health Syst Pharm. 2004 Mar 1;61(5):437.  PMID: 12892027.

 

Dutkiewics S. Efficacy and tolerability of drugs for treatment of benign prostatic hyperplasia. Int Urol Nephrol. 2001;32(3):423-32. PMID: 11583366.

" Xn Not dangerous goods.

LKT A4523 Alfuzosin Hydrochloride 500 mg 226.1 α1-adrenergic antagonist. (2RS)-N-[3-[(4-Amino-6, 7-dimethoxyquinazolin-2-yl)methylamino]propyl]tetrahydrofuran-2-carboxamide hydrochloride 81403-68-1 ≥98% 425.91 C19H27N5O4 HCl CN(CCCNC(=O)C1CCCO1)C2=NC3=CC(=C(C=C3C(=N2)N)OC)OC.Cl Ambient Ambient "Lacerda AE, Kuryshev YA, Chen Y, et al. Alfuzosin delays cardiac repolarization by a novel mechanism. J Pharmacol Exp Ther. 2008 Feb;324(2):427-33. PMID: 17986649.

 

Lee M. Alfuzosin hydrochloride for the treatment of benign prostatic hyperplasia. Am J Health Syst Pharm. 2003 Jul 15;60(14):1426-39. Erratum in: Am J Health Syst Pharm. 2004 Mar 1;61(5):437.  PMID: 12892027.

 

Dutkiewics S. Efficacy and tolerability of drugs for treatment of benign prostatic hyperplasia. Int Urol Nephrol. 2001;32(3):423-32. PMID: 11583366.

" Xn Not dangerous goods.

LKT A4523 Alfuzosin Hydrochloride 1 g 393.3 α1-adrenergic antagonist. (2RS)-N-[3-[(4-Amino-6, 7-dimethoxyquinazolin-2-yl)methylamino]propyl]tetrahydrofuran-2-carboxamide hydrochloride 81403-68-1 ≥98% 425.91 C19H27N5O4 HCl CN(CCCNC(=O)C1CCCO1)C2=NC3=CC(=C(C=C3C(=N2)N)OC)OC.Cl Ambient Ambient "Lacerda AE, Kuryshev YA, Chen Y, et al. Alfuzosin delays cardiac repolarization by a novel mechanism. J Pharmacol Exp Ther. 2008 Feb;324(2):427-33. PMID: 17986649.

 

Lee M. Alfuzosin hydrochloride for the treatment of benign prostatic hyperplasia. Am J Health Syst Pharm. 2003 Jul 15;60(14):1426-39. Erratum in: Am J Health Syst Pharm. 2004 Mar 1;61(5):437.  PMID: 12892027.

 

Dutkiewics S. Efficacy and tolerability of drugs for treatment of benign prostatic hyperplasia. Int Urol Nephrol. 2001;32(3):423-32. PMID: 11583366.

" Xn Not dangerous goods.

LKT "A4547

" Alloxan Monohydrate 5 g 33.9 Pyrimidine, glucose analog, used to induce diabetes. 2,4,5,6(1H,3H)-pyrimidinetetrone monohydrate Alloxan 2244-11-3 ≥98% 160.08 C4H2N2O4 C1(=O)C(C(=O)NC(=O)N1)(O)O Ambient 4°C Soluble in water. "Franzén S, Friederich-Persson M, Fasching A, et al. Differences in susceptibility to develop parameters of diabetic nephropathy in four mouse strains with type 1 diabetes. Am J Physiol Renal Physiol. 2014 May 15;306(10):F1171-8. PMID: 24623147.

 

Tyrberg B, Andersson A, Borg LA. Species differences in susceptibility of transplanted and cultured pancreatic islets to the beta-cell toxin alloxan. Gen Comp Endocrinol. 2001 Jun;122(3):238-51. PMID: 11356036.

 

Eizirik DL, Pipeleers DG, Ling Z, et al. Major species differences between humans and rodents in the susceptibility to pancreatic beta-cell injury. Proc Natl Acad Sci U S A. Sep 27;91(20):9253-6. PMID: 7937750.

" Xn, Xi Not dangerous goods.

LKT "A4547

" Alloxan Monohydrate 10 g 57.6 Pyrimidine, glucose analog, used to induce diabetes. 2,4,5,6(1H,3H)-pyrimidinetetrone monohydrate Alloxan 2244-11-3 ≥98% 160.08 C4H2N2O4 C1(=O)C(C(=O)NC(=O)N1)(O)O Ambient 4°C Soluble in water. "Franzén S, Friederich-Persson M, Fasching A, et al. Differences in susceptibility to develop parameters of diabetic nephropathy in four mouse strains with type 1 diabetes. Am J Physiol Renal Physiol. 2014 May 15;306(10):F1171-8. PMID: 24623147.

 

Tyrberg B, Andersson A, Borg LA. Species differences in susceptibility of transplanted and cultured pancreatic islets to the beta-cell toxin alloxan. Gen Comp Endocrinol. 2001 Jun;122(3):238-51. PMID: 11356036.

 

Eizirik DL, Pipeleers DG, Ling Z, et al. Major species differences between humans and rodents in the susceptibility to pancreatic beta-cell injury. Proc Natl Acad Sci U S A.  Sep 27;91(20):9253-6. PMID: 7937750.

" Xn, Xi Not dangerous goods.

LKT "A4547

" Alloxan Monohydrate 25 g 118.9 Pyrimidine, glucose analog, used to induce diabetes. 2,4,5,6(1H,3H)-pyrimidinetetrone monohydrate Alloxan 2244-11-3 ≥98% 160.08 C4H2N2O4 C1(=O)C(C(=O)NC(=O)N1)(O)O Ambient 4°C Soluble in water. "Franzén S, Friederich-Persson M, Fasching A, et al. Differences in susceptibility to develop parameters of diabetic nephropathy in four mouse strains with type 1 diabetes. Am J Physiol Renal Physiol. 2014 May 15;306(10):F1171-8. PMID: 24623147.

 

Tyrberg B, Andersson A, Borg LA. Species differences in susceptibility of transplanted and cultured pancreatic islets to the beta-cell toxin alloxan. Gen Comp Endocrinol. 2001 Jun;122(3):238-51. PMID: 11356036.

 

Eizirik DL, Pipeleers DG, Ling Z, et al. Major species differences between humans and rodents in the susceptibility to pancreatic beta-cell injury. Proc Natl Acad Sci U S A. Sep 27;91(20):9253-6. PMID: 7937750.

" Xn, Xi Not dangerous goods.

LKT A4577 Alsterpaullone 1 mg 171.7 GSK-3 and CDK inhibitor. 9-Nitro-7,12-dihydroindolo-[3,2-d][1]benzazepin-6(5)-one 237430-03-4 ≥98% 293.28 C16H11N3O3 C1C2=C(C3=CC=CC=C3NC1=O)NC4=C2C=C(C=C4)[N+](=O)[O-] Protect from light. Ambient 4°C Soluble in DMSO. "Cui C, Wang Y, Wang Y, et al. Alsterpaullone, a Cyclin-Dependent Kinase Inhibitor, Mediated Toxicity in HeLa Cells through Apoptosis-Inducing Effect. J Anal Methods Chem. 2013;2013:602091. PMID: 23577282.

 

Windsor PJ, Leys SP. Wnt signaling and induction in the sponge aquiferous system: evidence for an ancient origin of the organizer. Evol Dev. 2010 Sep-Oct;12(5):484-93. PMID: 20883217.

 

Zahler S, Liebl J, Fürst R, et al. Anti-angiogenic potential of small molecular inhibitors of cyclin dependent kinases in vitro. Angiogenesis. 2010 Sep;13(3):239-49. PMID: 20706783.

 

Fabres A, De Andrade CP, Guizzo M, et al. Effect of GSK-3 activity, enzymatic inhibition and gene silencing by RNAi on tick oviposition and egg hatching. Parasitology. 2010 Sep;137(10):1537-46. PMID: 20500916.

 

Guendel I, Agbottah ET, Kehn-Hall K, et al. Inhibition of human immunodeficiency virus type-1 by cdk inhibitors. AIDS Res Ther. 2010 Mar 24;7(1):7. PMID: 20334651.

 

Selenica ML, Jensen HS, Larsen AK, et al. Efficacy of small-molecule glycogen synthase kinase-3 inhibitors in the postnatal rat model of tau hyperphosphorylation. Br J Pharmacol. 2007 Nov;152(6):959-79. PMID: 17906685.

" Xi Not dangerous goods.

LKT A4577 Alsterpaullone 5 mg 772.1 GSK-3 and CDK inhibitor. 9-Nitro-7,12-dihydroindolo-[3,2-d][1]benzazepin-6(5)-one 237430-03-4 ≥98% 293.28 C16H11N3O3 C1C2=C(C3=CC=CC=C3NC1=O)NC4=C2C=C(C=C4)[N+](=O)[O-] Protect from light. Ambient 4°C Soluble in DMSO. "Cui C, Wang Y, Wang Y, et al. Alsterpaullone, a Cyclin-Dependent Kinase Inhibitor, Mediated Toxicity in HeLa Cells through Apoptosis-Inducing Effect. J Anal Methods Chem. 2013;2013:602091. PMID: 23577282.

 

Windsor PJ, Leys SP. Wnt signaling and induction in the sponge aquiferous system: evidence for an ancient origin of the organizer. Evol Dev. 2010 Sep-Oct;12(5):484-93. PMID: 20883217.

 

Zahler S, Liebl J, Fürst R, et al. Anti-angiogenic potential of small molecular inhibitors of cyclin dependent kinases in vitro. Angiogenesis. 2010 Sep;13(3):239-49. PMID: 20706783.

 

Fabres A, De Andrade CP, Guizzo M, et al. Effect of GSK-3 activity, enzymatic inhibition and gene silencing by RNAi on tick oviposition and egg hatching. Parasitology. 2010 Sep;137(10):1537-46. PMID: 20500916.

 

Guendel I, Agbottah ET, Kehn-Hall K, et al. Inhibition of human immunodeficiency virus type-1 by cdk inhibitors. AIDS Res Ther. 2010 Mar 24;7(1):7. PMID: 20334651.

 

Selenica ML, Jensen HS, Larsen AK, et al. Efficacy of small-molecule glycogen synthase kinase-3 inhibitors in the postnatal rat model of tau hyperphosphorylation. Br J Pharmacol. 2007 Nov;152(6):959-79. PMID: 17906685.

" Xi Not dangerous goods.

LKT A4578 Altretamine 500 mg 81.6 DNA alkylator. N,N,N',N',N'',N''-Hexamethyl-1,3,5-triazine-2,4,6-triamine HMM; Hexalen; Hexamethylmelamine 645-05-6 ≥98% 210.28 C9H18N6 CN(C)C1=NC(=NC(=N1)N(C)C)N(C)C Ambient 4°C Practically insoluble in water. Soluble in DMSO. "Chan JK, Loizzi V, Manetta A, et al. Oral altretamine used as salvage therapy in recurrent ovarian cancer. Gynecol Oncol. 2004 Jan;92(1):368-71. PMID: 14751188.

 

Coley HM, Brooks N, Phillips DH, et al. The role of the N-(hydroxymethyl)melamines as antitumour agents: mechanism of action studies. Biochem Pharmacol. 1995 May 11;49(9):1203-12. PMID: 7763301.

 

Hansen LA, Hughes TE. Altretamine. DICP. 1991 Feb;25(2):146-52. PMID: 1905441.

" Xn Not dangerous goods.

LKT A4578 Altretamine 1 g 136 DNA alkylator. N,N,N',N',N'',N''-Hexamethyl-1,3,5-triazine-2,4,6-triamine HMM; Hexalen; Hexamethylmelamine 645-05-6 ≥98% 210.28 C9H18N6 CN(C)C1=NC(=NC(=N1)N(C)C)N(C)C Ambient 4°C Practically insoluble in water. Soluble in DMSO. "Chan JK, Loizzi V, Manetta A, et al. Oral altretamine used as salvage therapy in recurrent ovarian cancer. Gynecol Oncol. 2004 Jan;92(1):368-71. PMID: 14751188.

 

Coley HM, Brooks N, Phillips DH, et al. The role of the N-(hydroxymethyl)melamines as antitumour agents: mechanism of action studies. Biochem Pharmacol. 1995 May 11;49(9):1203-12. PMID: 7763301.

 

Hansen LA, Hughes TE. Altretamine. DICP. 1991 Feb;25(2):146-52. PMID: 1905441.

" Xn Not dangerous goods.

LKT A4578 Altretamine 5 g 407.7 DNA alkylator. N,N,N',N',N'',N''-Hexamethyl-1,3,5-triazine-2,4,6-triamine HMM; Hexalen; Hexamethylmelamine 645-05-6 ≥98% 210.28 C9H18N6 CN(C)C1=NC(=NC(=N1)N(C)C)N(C)C Ambient 4°C Practically insoluble in water. Soluble in DMSO. "Chan JK, Loizzi V, Manetta A, et al. Oral altretamine used as salvage therapy in recurrent ovarian cancer. Gynecol Oncol. 2004 Jan;92(1):368-71. PMID: 14751188.

 

Coley HM, Brooks N, Phillips DH, et al. The role of the N-(hydroxymethyl)melamines as antitumour agents: mechanism of action studies. Biochem Pharmacol. 1995 May 11;49(9):1203-12. PMID: 7763301.

 

Hansen LA, Hughes TE. Altretamine. DICP. 1991 Feb;25(2):146-52. PMID: 1905441.

" Xn Not dangerous goods.

LKT A4606 Albendazole 10 g 67.9 Benzimidazole; microtubule polymerization inhibitor. Methyl 5-propylthio-2-benzimidazolecarbamate 5-(Propylthio)-2-carbomethoxyaminobenzimidazole; Bilutac; Valbazen; Zentel 54965-21-8 ≥95% 265.33 C12H15N3O2S CCCSC1=CC2=C(C=C1)N=C(N2)NC(=O)OC Ambient Ambient Slightly soluble in water. "Pourgholami MH, Akhter J, Wang L, et al. Antitumor activity of albendazole against the human colorectal cancer cell line HT-29: in vitro and in a xenograft model of peritoneal carcinomatosis. Cancer Chemother Pharmacol. 2005 May;55(5):425-32. PMID: 15565325.

 

Theodorides VJ, Gyurik RJ, Kingsbury WD, et al. Anthelmintic activity of albendazole against liver flukes, tapeworms., lung and gastrointestinal roundworms. Experientia. 1976 Jun 15;32(6):702-3. PMID: 950011.

" Xn Not dangerous goods.

LKT A4606 Albendazole 50 g 271.7 Benzimidazole; microtubule polymerization inhibitor. Methyl 5-propylthio-2-benzimidazolecarbamate 5-(Propylthio)-2-carbomethoxyaminobenzimidazole; Bilutac; Valbazen; Zentel 54965-21-8 ≥95% 265.33 C12H15N3O2S CCCSC1=CC2=C(C=C1)N=C(N2)NC(=O)OC Ambient Ambient Slightly soluble in water. "Pourgholami MH, Akhter J, Wang L, et al. Antitumor activity of albendazole against the human colorectal cancer cell line HT-29: in vitro and in a xenograft model of peritoneal carcinomatosis. Cancer Chemother Pharmacol. 2005 May;55(5):425-32. PMID: 15565325.

 

Theodorides VJ, Gyurik RJ, Kingsbury WD, et al. Anthelmintic activity of albendazole against liver flukes, tapeworms., lung and gastrointestinal roundworms. Experientia. 1976 Jun 15;32(6):702-3. PMID: 950011.

" Xn Not dangerous goods.

LKT A4802 Amantadine Hydrochloride 25 g 97.2 Viral M2 proton channel blocker, MAO-A, NET, NMDA,  α7 nAChR antagonist. Tricyclo[3.3.1.13,7]decan-1-amine hydrochloride Amazolon; Mantadan; Mantadine; Symmetrel; Vitrofral 665-66-7 ≥98% 187.71 C10H17N HCl C1C2CC3CC1CC(C2)(C3)N.Cl Ambient Ambient Soluble in water (400 mg/mL) or alcohol (196 mg/mL). Practically insoluble in ether. "Sommerauer C, Rebernik P, Reither H, et al. The noradrenaline transporter as site of action for the anti-Parkinson drug amantadine. Neuropharmacology. 2012 Mar;62(4):1708-16. PMID: 22155208.

 

Jing X, Ma C, Ohigashi Y, et al. Functional studies indicate amantadine binds to the pore of the influenza A virus M2 proton-selective ion channel. Proc Natl Acad Sci U S A. 2008 Aug 5;105(31):10967-72. PMID: 18669647.

 

Blanpied TA, Clarke RJ, Johnson JW. Amantadine inhibits NMDA receptors by accelerating channel closure during channel block. J Neurosci. 2005 Mar 30;25(13):3312-22. PMID: 15800186.

 

Pearce J. Mechanism of action of amantadine. Br Med J. 1971 Aug 26;3(5773):529. PMID: 4327681.

" Xn Not dangerous goods.

LKT A4802 Amantadine Hydrochloride 100 g 312.3 Viral M2 proton channel blocker, MAO-A, NET, NMDA,  α7 nAChR antagonist. Tricyclo[3.3.1.13,7]decan-1-amine hydrochloride Amazolon; Mantadan; Mantadine; Symmetrel; Vitrofral 665-66-7 ≥98% 187.71 C10H17N HCl C1C2CC3CC1CC(C2)(C3)N.Cl Ambient Ambient Soluble in water (400 mg/mL) or alcohol (196 mg/mL). Practically insoluble in ether. "Sommerauer C, Rebernik P, Reither H, et al. The noradrenaline transporter as site of action for the anti-Parkinson drug amantadine. Neuropharmacology. 2012 Mar;62(4):1708-16. PMID: 22155208.

 

Jing X, Ma C, Ohigashi Y, et al. Functional studies indicate amantadine binds to the pore of the influenza A virus M2 proton-selective ion channel. Proc Natl Acad Sci U S A. 2008 Aug 5;105(31):10967-72. PMID: 18669647.

 

Blanpied TA, Clarke RJ, Johnson JW. Amantadine inhibits NMDA receptors by accelerating channel closure during channel block. J Neurosci. 2005 Mar 30;25(13):3312-22. PMID: 15800186.

 

Pearce J. Mechanism of action of amantadine. Br Med J. 1971 Aug 26;3(5773):529. PMID: 4327681.

" Xn Not dangerous goods.

LKT A4803 Amantadine Sulfate 25 g 97.2 Viral M2 proton channel blocker, MAO-A, NET, NMDA,  α7 nAChR antagonist. Tricyclo[3.3.1.13,7]decan-1-amine sulfate PK-Merz; Trivaline 31377-23-8 ≥98% 400.58 (C10H17N)2 H2SO4 C1C2CC3CC1CC(C2)(C3)N.OS(=O)(=O)O Ambient Ambient "Sommerauer C, Rebernik P, Reither H, et al. The noradrenaline transporter as site of action for the anti-Parkinson drug amantadine. Neuropharmacology. 2012 Mar;62(4):1708-16. PMID: 22155208.

 

Jing X, Ma C, Ohigashi Y, et al. Functional studies indicate amantadine binds to the pore of the influenza A virus M2 proton-selective ion channel. Proc Natl Acad Sci U S A. 2008 Aug 5;105(31):10967-72. PMID: 18669647.

 

Blanpied TA, Clarke RJ, Johnson JW. Amantadine inhibits NMDA receptors by accelerating channel closure during channel block. J Neurosci. 2005 Mar 30;25(13):3312-22. PMID: 15800186.

 

Pearce J. Mechanism of action of amantadine. Br Med J. 1971 Aug 26;3(5773):529. PMID: 4327681.

" Not dangerous goods.

LKT A4803 Amantadine Sulfate 100 g 312.3 Viral M2 proton channel blocker, MAO-A, NET, NMDA,  α7 nAChR antagonist. Tricyclo[3.3.1.13,7]decan-1-amine sulfate PK-Merz; Trivaline 31377-23-8 ≥98% 400.58 (C10H17N)2 H2SO4 C1C2CC3CC1CC(C2)(C3)N.OS(=O)(=O)O Ambient Ambient "Sommerauer C, Rebernik P, Reither H, et al. The noradrenaline transporter as site of action for the anti-Parkinson drug amantadine. Neuropharmacology. 2012 Mar;62(4):1708-16. PMID: 22155208.

 

Jing X, Ma C, Ohigashi Y, et al. Functional studies indicate amantadine binds to the pore of the influenza A virus M2 proton-selective ion channel. Proc Natl Acad Sci U S A. 2008 Aug 5;105(31):10967-72. PMID: 18669647.

 

Blanpied TA, Clarke RJ, Johnson JW. Amantadine inhibits NMDA receptors by accelerating channel closure during channel block. J Neurosci. 2005 Mar 30;25(13):3312-22. PMID: 15800186.

 

Pearce J. Mechanism of action of amantadine. Br Med J. 1971 Aug 26;3(5773):529. PMID: 4327681.

" Not dangerous goods.

LKT A4805 Amastatin Hydrochloride 1 mg 74.8 Aminopeptidase inhibitor. "[(2S,3R)-3-Amino-2-hydroxy-5-methyl-hexanoyl]-Val-Val-Asp-OH . HCl

" 100938-10-1 ≥98% 511.01 C21H38N4O8 HCl CC(C)CC(C(C(=O)NC(C(C)C)C(=O)NC(C(C)C)C(=O)NC(CC(=O)O)C(=O)O)O)N.Cl Protect from light. Ambient 4°C Soluble in DMSO and acetic acid. "Tobin VA, Arechaga G, Brunton PJ, et al. Oxytocinase in the female rat hypothalamus: a novel mechanism controlling oxytocin neurones during lactation. J Neuroendocrinol. 2014 Apr;26(4):205-16. PMID: 24612105.

 

Pillay D, Boulangé AF, Coustou V, et al. Recombinant expression and biochemical characterisation of two alanyl aminopeptidases of Trypanosoma congolense. Exp Parasitol. 2013 Dec;135(4):675-84. PMID: 24177338.

 

Batt CM, Klein EW, Harding JW, et al. Pressor responses to amastatin, bestatin and Plummer's inhibitors are suppressed by pretreatment with the angiotensin receptor antagonist sarthran. Brain Res Bull. 1988 Nov;21(5):731-5. PMID: 3219604.

" Not dangerous goods.

LKT A4805 Amastatin Hydrochloride 5 mg 306.5 Aminopeptidase inhibitor. "[(2S,3R)-3-Amino-2-hydroxy-5-methyl-hexanoyl]-Val-Val-Asp-OH . HCl

" 100938-10-1 ≥98% 511.01 C21H38N4O8 HCl CC(C)CC(C(C(=O)NC(C(C)C)C(=O)NC(C(C)C)C(=O)NC(CC(=O)O)C(=O)O)O)N.Cl Protect from light. Ambient 4°C Soluble in DMSO and acetic acid. "Tobin VA, Arechaga G, Brunton PJ, et al. Oxytocinase in the female rat hypothalamus: a novel mechanism controlling oxytocin neurones during lactation. J Neuroendocrinol. 2014 Apr;26(4):205-16. PMID: 24612105.

 

Pillay D, Boulangé AF, Coustou V, et al. Recombinant expression and biochemical characterisation of two alanyl aminopeptidases of Trypanosoma congolense. Exp Parasitol. 2013 Dec;135(4):675-84. PMID: 24177338.

 

Batt CM, Klein EW, Harding JW, et al. Pressor responses to amastatin, bestatin and Plummer's inhibitors are suppressed by pretreatment with the angiotensin receptor antagonist sarthran. Brain Res Bull. 1988 Nov;21(5):731-5. PMID: 3219604.

" Not dangerous goods.

LKT A4805 Amastatin Hydrochloride 10 mg 583 Aminopeptidase inhibitor. "[(2S,3R)-3-Amino-2-hydroxy-5-methyl-hexanoyl]-Val-Val-Asp-OH . HCl

" 100938-10-1 ≥98% 511.01 C21H38N4O8 HCl CC(C)CC(C(C(=O)NC(C(C)C)C(=O)NC(C(C)C)C(=O)NC(CC(=O)O)C(=O)O)O)N.Cl Protect from light. Ambient 4°C Soluble in DMSO and acetic acid. "Tobin VA, Arechaga G, Brunton PJ, et al. Oxytocinase in the female rat hypothalamus: a novel mechanism controlling oxytocin neurones during lactation. J Neuroendocrinol. 2014 Apr;26(4):205-16. PMID: 24612105.

 

Pillay D, Boulangé AF, Coustou V, et al. Recombinant expression and biochemical characterisation of two alanyl aminopeptidases of Trypanosoma congolense. Exp Parasitol. 2013 Dec;135(4):675-84. PMID: 24177338.

 

Batt CM, Klein EW, Harding JW, et al. Pressor responses to amastatin, bestatin and Plummer's inhibitors are suppressed by pretreatment with the angiotensin receptor antagonist sarthran. Brain Res Bull. 1988 Nov;21(5):731-5. PMID: 3219604.

" Not dangerous goods.

LKT A4806 Ambroxol Hydrochloride 1 g 44.4 Expectorant. 4-[[(2-amino-3,5-dibromophenyl)methyl]amino]- cyclohexanol hydrochloride Abramen; Ambril; Duramucal; Fluibron; Fluixol; Mucolear; Mucosolvan 23828-92-4 ≥98% 414.57 C13H18Br2N2O HCl C1CC(CCC1NCC2=CC(=CC(=C2N)Br)Br)O.Cl Protect from light. Ambient Ambient Soluble in methanol. "Huang J, Xu J, Tian L, et al. A thioredoxin reductase and/or thioredoxin system-based mechanism for antioxidant effects of ambroxol. Biochimie. 2014 Feb;97:92-103. PMID: 24103200.

 

Utsugi M, Dobashi K, Koga Y, et al. Ambroxol inhibits platelet-derived growth factor production in human monocytic cells. Eur J Pharmacol. 2002 Feb 1;436(1-2):47-51. PMID: 11834245.

 

Severina IS, Bussygina OG, Pyatakova NV, et al. Ambroxol as an inhibitor of nitric oxide-dependent activation of soluble guanylate cyclase. Eur J Pharmacol. 2000 Oct 27;407(1-2):61-4. PMID: 11050291.

 

Disse BG, Ziegler HW. Pharmacodynamic mechanism and therapeutic activity of ambroxol in animal experiments. Respiration. 1987;51 Suppl 1:15-22. PMID: 3602598.

" Xn Not dangerous goods.

LKT A4806 Ambroxol Hydrochloride 5 g 76.2 Expectorant. 4-[[(2-amino-3,5-dibromophenyl)methyl]amino]- cyclohexanol hydrochloride Abramen; Ambril; Duramucal; Fluibron; Fluixol; Mucolear; Mucosolvan 23828-92-4 ≥98% 414.57 C13H18Br2N2O HCl C1CC(CCC1NCC2=CC(=CC(=C2N)Br)Br)O.Cl Protect from light. Ambient Ambient Soluble in methanol. "Huang J, Xu J, Tian L, et al. A thioredoxin reductase and/or thioredoxin system-based mechanism for antioxidant effects of ambroxol. Biochimie. 2014 Feb;97:92-103. PMID: 24103200.

 

Utsugi M, Dobashi K, Koga Y, et al. Ambroxol inhibits platelet-derived growth factor production in human monocytic cells. Eur J Pharmacol. 2002 Feb 1;436(1-2):47-51. PMID: 11834245.

 

Severina IS, Bussygina OG, Pyatakova NV, et al. Ambroxol as an inhibitor of nitric oxide-dependent activation of soluble guanylate cyclase. Eur J Pharmacol. 2000 Oct 27;407(1-2):61-4. PMID: 11050291.

 

Disse BG, Ziegler HW. Pharmacodynamic mechanism and therapeutic activity of ambroxol in animal experiments. Respiration. 1987;51 Suppl 1:15-22. PMID: 3602598.

" Xn Not dangerous goods.

LKT A4806 Ambroxol Hydrochloride 25 g 254 Expectorant. 4-[[(2-amino-3,5-dibromophenyl)methyl]amino]- cyclohexanol hydrochloride Abramen; Ambril; Duramucal; Fluibron; Fluixol; Mucolear; Mucosolvan 23828-92-4 ≥98% 414.57 C13H18Br2N2O HCl C1CC(CCC1NCC2=CC(=CC(=C2N)Br)Br)O.Cl Protect from light. Ambient Ambient Soluble in methanol. "Huang J, Xu J, Tian L, et al. A thioredoxin reductase and/or thioredoxin system-based mechanism for antioxidant effects of ambroxol. Biochimie. 2014 Feb;97:92-103. PMID: 24103200.

 

Utsugi M, Dobashi K, Koga Y, et al. Ambroxol inhibits platelet-derived growth factor production in human monocytic cells. Eur J Pharmacol. 2002 Feb 1;436(1-2):47-51. PMID: 11834245.

 

Severina IS, Bussygina OG, Pyatakova NV, et al. Ambroxol as an inhibitor of nitric oxide-dependent activation of soluble guanylate cyclase. Eur J Pharmacol. 2000 Oct 27;407(1-2):61-4. PMID: 11050291.

 

Disse BG, Ziegler HW. Pharmacodynamic mechanism and therapeutic activity of ambroxol in animal experiments. Respiration. 1987;51 Suppl 1:15-22. PMID: 3602598.

" Xn Not dangerous goods.

LKT A4844 Amylin (8-37), human 0.5 mg 324 Endogenous peptide hormone inolved in gastric emptying, gastric acid secretion, enteric contraction; calcitonin-RAMP agonist. IAPP; islet amyloid precursor peptide ≥95% 3184.5 C138H215N41O46 Ambient -20°C "Paulsson JF, Westermark GT. Aberrant processing of human proislet amyloid polypeptide results in increased amyloid formation. Diabetes. 2005 Jul;54(7):2117-25. PMID: 15983213.

 

Ratner RE, Dickey R, Fineman M, et al. Amylin replacement with pramlintide as an adjunct to insulin therapy improves long-term glycaemic and weight control in Type 1 diabetes mellitus: a 1-year, randomized controlled trial. Diabet Med. 2004 Nov;21(11):1204-12. PMID: 15498087.

 

Pittner RA, Albrandt K, Beaumont K, et al. Molecular physiology of amylin. J Cell Biochem. 1994;55 Suppl:19-28. PMID: 7929615.

" Not dangerous goods.

LKT A4844 Amylin (8-37), human 1 mg 552 Endogenous peptide hormone inolved in gastric emptying, gastric acid secretion, enteric contraction; calcitonin-RAMP agonist. IAPP; islet amyloid precursor peptide ≥95% 3184.5 C138H215N41O46 Ambient -20°C "Paulsson JF, Westermark GT. Aberrant processing of human proislet amyloid polypeptide results in increased amyloid formation. Diabetes. 2005 Jul;54(7):2117-25. PMID: 15983213.

 

Ratner RE, Dickey R, Fineman M, et al. Amylin replacement with pramlintide as an adjunct to insulin therapy improves long-term glycaemic and weight control in Type 1 diabetes mellitus: a 1-year, randomized controlled trial. Diabet Med. 2004 Nov;21(11):1204-12. PMID: 15498087.

 

Pittner RA, Albrandt K, Beaumont K, et al. Molecular physiology of amylin. J Cell Biochem. 1994;55 Suppl:19-28. PMID: 7929615.

" Not dangerous goods.

LKT A4844 Amylin (8-37), human 2.5 mg 972.1 Endogenous peptide hormone inolved in gastric emptying, gastric acid secretion, enteric contraction; calcitonin-RAMP agonist. IAPP; islet amyloid precursor peptide ≥95% 3184.5 C138H215N41O46 Ambient -20°C "Paulsson JF, Westermark GT. Aberrant processing of human proislet amyloid polypeptide results in increased amyloid formation. Diabetes. 2005 Jul;54(7):2117-25. PMID: 15983213.

 

Ratner RE, Dickey R, Fineman M, et al. Amylin replacement with pramlintide as an adjunct to insulin therapy improves long-term glycaemic and weight control in Type 1 diabetes mellitus: a 1-year, randomized controlled trial. Diabet Med. 2004 Nov;21(11):1204-12. PMID: 15498087.

 

Pittner RA, Albrandt K, Beaumont K, et al. Molecular physiology of amylin. J Cell Biochem. 1994;55 Suppl:19-28. PMID: 7929615.

" Not dangerous goods.

LKT A4845 Amylin (8-37), rat 0.5 mg 324 Endogenous peptide hormone inolved in gastric emptying, gastric acid secretion, enteric contraction; calcitonin-RAMP agonist. IAPP; islet amyloid precursor peptide ≥95% 3200.63 C140H227N43O43 Ambient -20°C "Paulsson JF, Westermark GT. Aberrant processing of human proislet amyloid polypeptide results in increased amyloid formation. Diabetes. 2005 Jul;54(7):2117-25. PMID: 15983213.

 

Ratner RE, Dickey R, Fineman M, et al. Amylin replacement with pramlintide as an adjunct to insulin therapy improves long-term glycaemic and weight control in Type 1 diabetes mellitus: a 1-year, randomized controlled trial. Diabet Med. 2004 Nov;21(11):1204-12. PMID: 15498087.

 

Pittner RA, Albrandt K, Beaumont K, et al. Molecular physiology of amylin. J Cell Biochem. 1994;55 Suppl:19-28. PMID: 7929615.

" Not dangerous goods.

LKT A4845 Amylin (8-37), rat 1 mg 552 Endogenous peptide hormone inolved in gastric emptying, gastric acid secretion, enteric contraction; calcitonin-RAMP agonist. IAPP; islet amyloid precursor peptide ≥95% 3200.63 C140H227N43O43 Ambient -20°C "Paulsson JF, Westermark GT. Aberrant processing of human proislet amyloid polypeptide results in increased amyloid formation. Diabetes. 2005 Jul;54(7):2117-25. PMID: 15983213.

 

Ratner RE, Dickey R, Fineman M, et al. Amylin replacement with pramlintide as an adjunct to insulin therapy improves long-term glycaemic and weight control in Type 1 diabetes mellitus: a 1-year, randomized controlled trial. Diabet Med. 2004 Nov;21(11):1204-12. PMID: 15498087.

 

Pittner RA, Albrandt K, Beaumont K, et al. Molecular physiology of amylin. J Cell Biochem. 1994;55 Suppl:19-28. PMID: 7929615.

" Not dangerous goods.

LKT A4845 Amylin (8-37), rat 2.5 mg 972.1 Endogenous peptide hormone inolved in gastric emptying, gastric acid secretion, enteric contraction; calcitonin-RAMP agonist. IAPP; islet amyloid precursor peptide ≥95% 3200.63 C140H227N43O43 Ambient -20°C "Paulsson JF, Westermark GT. Aberrant processing of human proislet amyloid polypeptide results in increased amyloid formation. Diabetes. 2005 Jul;54(7):2117-25. PMID: 15983213.

 

Ratner RE, Dickey R, Fineman M, et al. Amylin replacement with pramlintide as an adjunct to insulin therapy improves long-term glycaemic and weight control in Type 1 diabetes mellitus: a 1-year, randomized controlled trial. Diabet Med. 2004 Nov;21(11):1204-12. PMID: 15498087.

 

Pittner RA, Albrandt K, Beaumont K, et al. Molecular physiology of amylin. J Cell Biochem. 1994;55 Suppl:19-28. PMID: 7929615.

" Not dangerous goods.

LKT A4846 Amylin, cat 0.5 mg 348 Endogenous peptide hormone inolved in gastric emptying, gastric acid secretion, enteric contraction; calcitonin-RAMP agonist. IAPP; islet amyloid precursor peptide ≥95% 3910.45 C165H270N52O54S2 Ambient -20°C "Paulsson JF, Westermark GT. Aberrant processing of human proislet amyloid polypeptide results in increased amyloid formation. Diabetes. 2005 Jul;54(7):2117-25. PMID: 15983213.

 

Ratner RE, Dickey R, Fineman M, et al. Amylin replacement with pramlintide as an adjunct to insulin therapy improves long-term glycaemic and weight control in Type 1 diabetes mellitus: a 1-year, randomized controlled trial. Diabet Med. 2004 Nov;21(11):1204-12. PMID: 15498087.

 

Pittner RA, Albrandt K, Beaumont K, et al. Molecular physiology of amylin. J Cell Biochem. 1994;55 Suppl:19-28. PMID: 7929615.

" Not dangerous goods.

LKT A4846 Amylin, cat 1 mg 591 Endogenous peptide hormone inolved in gastric emptying, gastric acid secretion, enteric contraction; calcitonin-RAMP agonist. IAPP; islet amyloid precursor peptide ≥95% 3910.45 C165H270N52O54S2 Ambient -20°C "Paulsson JF, Westermark GT. Aberrant processing of human proislet amyloid polypeptide results in increased amyloid formation. Diabetes. 2005 Jul;54(7):2117-25. PMID: 15983213.

 

Ratner RE, Dickey R, Fineman M, et al. Amylin replacement with pramlintide as an adjunct to insulin therapy improves long-term glycaemic and weight control in Type 1 diabetes mellitus: a 1-year, randomized controlled trial. Diabet Med. 2004 Nov;21(11):1204-12. PMID: 15498087.

 

Pittner RA, Albrandt K, Beaumont K, et al. Molecular physiology of amylin. J Cell Biochem. 1994;55 Suppl:19-28. PMID: 7929615.

" Not dangerous goods.

LKT A4846 Amylin, cat 2.5 mg 1043.9 Endogenous peptide hormone inolved in gastric emptying, gastric acid secretion, enteric contraction; calcitonin-RAMP agonist. IAPP; islet amyloid precursor peptide ≥95% 3910.45 C165H270N52O54S2 Ambient -20°C "Paulsson JF, Westermark GT. Aberrant processing of human proislet amyloid polypeptide results in increased amyloid formation. Diabetes. 2005 Jul;54(7):2117-25. PMID: 15983213.

 

Ratner RE, Dickey R, Fineman M, et al. Amylin replacement with pramlintide as an adjunct to insulin therapy improves long-term glycaemic and weight control in Type 1 diabetes mellitus: a 1-year, randomized controlled trial. Diabet Med. 2004 Nov;21(11):1204-12. PMID: 15498087.

 

Pittner RA, Albrandt K, Beaumont K, et al. Molecular physiology of amylin. J Cell Biochem. 1994;55 Suppl:19-28. PMID: 7929615.

" Not dangerous goods.

LKT A4847 Amylin, human 0.5 mg 193.5 Endogenous peptide hormone inolved in gastric emptying, gastric acid secretion, enteric contraction; calcitonin-RAMP agonist. Amlintide 122384-88-7 ≥95% 3903.4 C165H261N51O55S2 CCC(C)C(C(=O)NC(CC(C)C)C(=O)NC(CO)C(=O)NC(CO)C(=O)NC(C(C)O)C(=O)NC(CC(=O)N)C(=O)NC(C(C)C)C(=O)NCC(=O)NC(CO)C(=O)NC(CC(=O)N)C(=O)NC(C(C)O)C(=O)NC(CC1=CC=C(C=C1)O)C(=O)N)NC(=O)C(C)NC(=O)CNC(=O)C(CC2=CC=CC=C2)NC(=O)C(CC(=O)N)NC(=O)C(CC(=O)N)NC(=O)C(CO)NC(=O)C(CO)NC(=O)C(CC3=CN=CN3)NC(=O)C(C(C)C)NC(=O)C(CC(C)C)NC(=O)C(CC4=CC=CC=C4)NC(=O)C(CC(=O)N)NC(=O)C(C)NC(=O)C(CC(C)C)NC(=O)C(CCCNC(=N)N)NC(=O)C(CCC(=O)N)NC(=O)C(C(C)O)NC(=O)C(C)NC(=O)C5CSSCC(C(=O)NC(C(=O)NC(C(=O)NC(C(=O)NC(C(=O)N5)C(C)O)C)C(C)O)CC(=O)N)NC(=O)C(CCCCN)N Ambient -20°C Soluble in 5% acetic acid. "Paulsson JF, Westermark GT. Aberrant processing of human proislet amyloid polypeptide results in increased amyloid formation. Diabetes. 2005 Jul;54(7):2117-25. PMID: 15983213.

 

Ratner RE, Dickey R, Fineman M, et al. Amylin replacement with pramlintide as an adjunct to insulin therapy improves long-term glycaemic and weight control in Type 1 diabetes mellitus: a 1-year, randomized controlled trial. Diabet Med. 2004 Nov;21(11):1204-12. PMID: 15498087.

 

Pittner RA, Albrandt K, Beaumont K, et al. Molecular physiology of amylin. J Cell Biochem. 1994;55 Suppl:19-28. PMID: 7929615.

" Not dangerous goods.

LKT A4847 Amylin, human 1 mg 327.7 Endogenous peptide hormone inolved in gastric emptying, gastric acid secretion, enteric contraction; calcitonin-RAMP agonist. Amlintide 122384-88-7 ≥95% 3903.4 C165H261N51O55S2 CCC(C)C(C(=O)NC(CC(C)C)C(=O)NC(CO)C(=O)NC(CO)C(=O)NC(C(C)O)C(=O)NC(CC(=O)N)C(=O)NC(C(C)C)C(=O)NCC(=O)NC(CO)C(=O)NC(CC(=O)N)C(=O)NC(C(C)O)C(=O)NC(CC1=CC=C(C=C1)O)C(=O)N)NC(=O)C(C)NC(=O)CNC(=O)C(CC2=CC=CC=C2)NC(=O)C(CC(=O)N)NC(=O)C(CC(=O)N)NC(=O)C(CO)NC(=O)C(CO)NC(=O)C(CC3=CN=CN3)NC(=O)C(C(C)C)NC(=O)C(CC(C)C)NC(=O)C(CC4=CC=CC=C4)NC(=O)C(CC(=O)N)NC(=O)C(C)NC(=O)C(CC(C)C)NC(=O)C(CCCNC(=N)N)NC(=O)C(CCC(=O)N)NC(=O)C(C(C)O)NC(=O)C(C)NC(=O)C5CSSCC(C(=O)NC(C(=O)NC(C(=O)NC(C(=O)NC(C(=O)N5)C(C)O)C)C(C)O)CC(=O)N)NC(=O)C(CCCCN)N Ambient -20°C Soluble in 5% acetic acid. "Paulsson JF, Westermark GT. Aberrant processing of human proislet amyloid polypeptide results in increased amyloid formation. Diabetes. 2005 Jul;54(7):2117-25. PMID: 15983213.

 

Ratner RE, Dickey R, Fineman M, et al. Amylin replacement with pramlintide as an adjunct to insulin therapy improves long-term glycaemic and weight control in Type 1 diabetes mellitus: a 1-year, randomized controlled trial. Diabet Med. 2004 Nov;21(11):1204-12. PMID: 15498087.

 

Pittner RA, Albrandt K, Beaumont K, et al. Molecular physiology of amylin. J Cell Biochem. 1994;55 Suppl:19-28. PMID: 7929615.

" Not dangerous goods.

LKT A4847 Amylin, human 2.5 mg 579.8 Endogenous peptide hormone inolved in gastric emptying, gastric acid secretion, enteric contraction; calcitonin-RAMP agonist. Amlintide 122384-88-7 ≥95% 3903.4 C165H261N51O55S2 CCC(C)C(C(=O)NC(CC(C)C)C(=O)NC(CO)C(=O)NC(CO)C(=O)NC(C(C)O)C(=O)NC(CC(=O)N)C(=O)NC(C(C)C)C(=O)NCC(=O)NC(CO)C(=O)NC(CC(=O)N)C(=O)NC(C(C)O)C(=O)NC(CC1=CC=C(C=C1)O)C(=O)N)NC(=O)C(C)NC(=O)CNC(=O)C(CC2=CC=CC=C2)NC(=O)C(CC(=O)N)NC(=O)C(CC(=O)N)NC(=O)C(CO)NC(=O)C(CO)NC(=O)C(CC3=CN=CN3)NC(=O)C(C(C)C)NC(=O)C(CC(C)C)NC(=O)C(CC4=CC=CC=C4)NC(=O)C(CC(=O)N)NC(=O)C(C)NC(=O)C(CC(C)C)NC(=O)C(CCCNC(=N)N)NC(=O)C(CCC(=O)N)NC(=O)C(C(C)O)NC(=O)C(C)NC(=O)C5CSSCC(C(=O)NC(C(=O)NC(C(=O)NC(C(=O)NC(C(=O)N5)C(C)O)C)C(C)O)CC(=O)N)NC(=O)C(CCCCN)N Ambient -20°C Soluble in 5% acetic acid. "Paulsson JF, Westermark GT. Aberrant processing of human proislet amyloid polypeptide results in increased amyloid formation. Diabetes. 2005 Jul;54(7):2117-25. PMID: 15983213.

 

Ratner RE, Dickey R, Fineman M, et al. Amylin replacement with pramlintide as an adjunct to insulin therapy improves long-term glycaemic and weight control in Type 1 diabetes mellitus: a 1-year, randomized controlled trial. Diabet Med. 2004 Nov;21(11):1204-12. PMID: 15498087.

 

Pittner RA, Albrandt K, Beaumont K, et al. Molecular physiology of amylin. J Cell Biochem. 1994;55 Suppl:19-28. PMID: 7929615.

" Not dangerous goods.

LKT A4848 Amyloid-β (1-40) 1 mg 605 Endogenous APP peptide cleavage product, primary component in amyloid plaques typical of Alzheimer’s disease. Amyloid-beta protein fragment (1-40) 131438-79-4 ≥98% 4329.8 C194H295N53O58S CCC(C)C(C(=O)NC(C(C)CC)C(=O)NCC(=O)NC(CC(C)C)C(=O)NC(CCSC)C(=O)NC(C(C)C)C(=O)NCC(=O)NCC(=O)NC(C(C)C)C(=O)NC(C(C)C)C(=O)O)NC(=O)C(C)NC(=O)CNC(=O)C(CCCCN)NC(=O)C(CC(=O)N)NC(=O)C(CO)NC(=O)CNC(=O)C(C(C)C)NC(=O)C(CC(=O)O)NC(=O)C(CCC(=O)O)NC(=O)C(C)NC(=O)C(CC1=CC=CC=C1)NC(=O)C(CC2=CC=CC=C2)NC(=O)C(C(C)C)NC(=O)C(CC(C)C)NC(=O)C(CCCCN)NC(=O)C(CCC(=O)N)NC(=O)C(CC3=CNC=N3)NC(=O)C(CC4=CNC=N4)NC(=O)C(C(C)C)NC(=O)C(CCC(=O)O)NC(=O)C(CC5=CC=C(C=C5)O)NC(=O)CNC(=O)C(CO)NC(=O)C(CC(=O)O)NC(=O)C(CC6=CNC=N6)NC(=O)C(CCCNC(=N)N)NC(=O)C(CC7=CC=CC=C7)NC(=O)C(CCC(=O)O)NC(=O)C(C)NC(=O)C(CC(=O)O)N Ambient -20°C Soluble in water (~6mg/mL). Not directly soluble in buffer or saline. "Hu J, el-Fakahany EE.  Neuroreport.  4(6):760-762 (1993).Jia J, Kang L, Li S, et al. Amelioratory effects of testosterone treatment on cognitive performance deficits induced by soluble Aβ1-42 oligomers injected into the hippocampus. Horm Behav. 2013 Aug;64(3):477-86. PMID: 23954394.

 

Yin YI, Bassit B, Zhu L, et al. gamma-Secretase Substrate Concentration Modulates the Abeta42/Abeta40 Ratio: Implications for Alzheimer Disease. J Biol Chem. 2007 Aug 10;282(32):23639-44. PMID: 17556361.

 

Hartmann T, Bieger SC, Brühl B, et al. Distinct sites of intracellular production for Alzheimer's disease A beta40/42 amyloid peptides. Nat Med. 1997 Sep;3(9):1016-20. PMID: 9288729.

" Not dangerous goods.

LKT A4849 Amyloid-β (25-35) 1 mg 52 Endogenous APP peptide cleavage product, primary component in amyloid plaques typical of Alzheimer’s disease. Amyloid-beta protein fragment (25-35) 131602-53-4 ≥95% 1060.27 C45H81N13O14S CCC(C)C(C(=O)NC(C(C)CC)C(=O)NCC(=O)NC(CC(C)C)C(=O)NC(CCSC)C(=O)O)NC(=O)C(C)NC(=O)CNC(=O)C(CCCCN)NC(=O)C(CC(=O)N)NC(=O)C(CO)NC(=O)CN Ambient -20°C Soluble in water (~6mg/mL). Not directly soluble in buffer or saline. "Hu J, el-Fakahany EE.  Neuroreport.  4(6):760-762 (1993).Jia J, Kang L, Li S, et al. Amelioratory effects of testosterone treatment on cognitive performance deficits induced by soluble Aβ1-42 oligomers injected into the hippocampus. Horm Behav. 2013 Aug;64(3):477-86. PMID: 23954394.

 

Yin YI, Bassit B, Zhu L, et al. gamma-Secretase Substrate Concentration Modulates the Abeta42/Abeta40 Ratio: Implications for Alzheimer Disease. J Biol Chem. 2007 Aug 10;282(32):23639-44. PMID: 17556361.

 

Hartmann T, Bieger SC, Brühl B, et al. Distinct sites of intracellular production for Alzheimer's disease A beta40/42 amyloid peptides. Nat Med. 1997 Sep;3(9):1016-20. PMID: 9288729.

" Not dangerous goods.

LKT A4849 Amyloid-β (25-35) 2 mg 127.1 Endogenous APP peptide cleavage product, primary component in amyloid plaques typical of Alzheimer’s disease. Amyloid-beta protein fragment (25-35) 131602-53-4 ≥95% 1060.27 C45H81N13O14S CCC(C)C(C(=O)NC(C(C)CC)C(=O)NCC(=O)NC(CC(C)C)C(=O)NC(CCSC)C(=O)O)NC(=O)C(C)NC(=O)CNC(=O)C(CCCCN)NC(=O)C(CC(=O)N)NC(=O)C(CO)NC(=O)CN Ambient -20°C Soluble in water (~6mg/mL). Not directly soluble in buffer or saline. "Hu J, el-Fakahany EE.  Neuroreport.  4(6):760-762 (1993).Jia J, Kang L, Li S, et al. Amelioratory effects of testosterone treatment on cognitive performance deficits induced by soluble Aβ1-42 oligomers injected into the hippocampus. Horm Behav. 2013 Aug;64(3):477-86. PMID: 23954394.

 

Yin YI, Bassit B, Zhu L, et al. gamma-Secretase Substrate Concentration Modulates the Abeta42/Abeta40 Ratio: Implications for Alzheimer Disease. J Biol Chem. 2007 Aug 10;282(32):23639-44. PMID: 17556361.

 

Hartmann T, Bieger SC, Brühl B, et al. Distinct sites of intracellular production for Alzheimer's disease A beta40/42 amyloid peptides. Nat Med. 1997 Sep;3(9):1016-20. PMID: 9288729.

" Not dangerous goods.

LKT A4849 Amyloid-β (25-35) 5 mg 346.5 Endogenous APP peptide cleavage product, primary component in amyloid plaques typical of Alzheimer’s disease. Amyloid-beta protein fragment (25-35) 131602-53-4 ≥95% 1060.27 C45H81N13O14S CCC(C)C(C(=O)NC(C(C)CC)C(=O)NCC(=O)NC(CC(C)C)C(=O)NC(CCSC)C(=O)O)NC(=O)C(C)NC(=O)CNC(=O)C(CCCCN)NC(=O)C(CC(=O)N)NC(=O)C(CO)NC(=O)CN Ambient -20°C Soluble in water (~6mg/mL). Not directly soluble in buffer or saline. "Hu J, el-Fakahany EE.  Neuroreport.  4(6):760-762 (1993).Jia J, Kang L, Li S, et al. Amelioratory effects of testosterone treatment on cognitive performance deficits induced by soluble Aβ1-42 oligomers injected into the hippocampus. Horm Behav. 2013 Aug;64(3):477-86. PMID: 23954394.

 

Yin YI, Bassit B, Zhu L, et al. gamma-Secretase Substrate Concentration Modulates the Abeta42/Abeta40 Ratio: Implications for Alzheimer Disease. J Biol Chem. 2007 Aug 10;282(32):23639-44. PMID: 17556361.

 

Hartmann T, Bieger SC, Brühl B, et al. Distinct sites of intracellular production for Alzheimer's disease A beta40/42 amyloid peptides. Nat Med. 1997 Sep;3(9):1016-20. PMID: 9288729.

" Not dangerous goods.

LKT A4850 Amylin, rat 0.5 mg 276.2 Endogenous peptide hormone inolved in gastric emptying, gastric acid secretion, enteric contraction; calcitonin-RAMP agonist. IAPP; islet amyloid precursor peptide ≥95% 3918.47 C167H270N52O53S2 Ambient -20°C "Paulsson JF, Westermark GT. Aberrant processing of human proislet amyloid polypeptide results in increased amyloid formation. Diabetes. 2005 Jul;54(7):2117-25. PMID: 15983213.

 

Ratner RE, Dickey R, Fineman M, et al. Amylin replacement with pramlintide as an adjunct to insulin therapy improves long-term glycaemic and weight control in Type 1 diabetes mellitus: a 1-year, randomized controlled trial. Diabet Med. 2004 Nov;21(11):1204-12. PMID: 15498087.

 

Pittner RA, Albrandt K, Beaumont K, et al. Molecular physiology of amylin. J Cell Biochem. 1994;55 Suppl:19-28. PMID: 7929615.

" Not dangerous goods.

LKT A4850 Amylin, rat 1 mg 468.2 Endogenous peptide hormone inolved in gastric emptying, gastric acid secretion, enteric contraction; calcitonin-RAMP agonist. IAPP; islet amyloid precursor peptide ≥95% 3918.47 C167H270N52O53S2 Ambient -20°C "Paulsson JF, Westermark GT. Aberrant processing of human proislet amyloid polypeptide results in increased amyloid formation. Diabetes. 2005 Jul;54(7):2117-25. PMID: 15983213.

 

Ratner RE, Dickey R, Fineman M, et al. Amylin replacement with pramlintide as an adjunct to insulin therapy improves long-term glycaemic and weight control in Type 1 diabetes mellitus: a 1-year, randomized controlled trial. Diabet Med. 2004 Nov;21(11):1204-12. PMID: 15498087.

 

Pittner RA, Albrandt K, Beaumont K, et al. Molecular physiology of amylin. J Cell Biochem. 1994;55 Suppl:19-28. PMID: 7929615.

" Not dangerous goods.

LKT A4850 Amylin, rat 2.5 mg 828.1 Endogenous peptide hormone inolved in gastric emptying, gastric acid secretion, enteric contraction; calcitonin-RAMP agonist. IAPP; islet amyloid precursor peptide ≥95% 3918.47 C167H270N52O53S2 Ambient -20°C "Paulsson JF, Westermark GT. Aberrant processing of human proislet amyloid polypeptide results in increased amyloid formation. Diabetes. 2005 Jul;54(7):2117-25. PMID: 15983213.

 

Ratner RE, Dickey R, Fineman M, et al. Amylin replacement with pramlintide as an adjunct to insulin therapy improves long-term glycaemic and weight control in Type 1 diabetes mellitus: a 1-year, randomized controlled trial. Diabet Med. 2004 Nov;21(11):1204-12. PMID: 15498087.

 

Pittner RA, Albrandt K, Beaumont K, et al. Molecular physiology of amylin. J Cell Biochem. 1994;55 Suppl:19-28. PMID: 7929615.

" Not dangerous goods.

LKT A4851 β-Amyloid Peptide (1-40), rat 0.5 mg 396.1 Endogenous APP peptide cleavage product, primary component in amyloid plaques typical of Alzheimer’s disease. Amyloid-β (1-40) 131438-79-4 ≥95% 4233.81 C190H291N51O57S1 "CCC(C)C(C(=O)NC(C(C)CC)C(=O)NCC(=O)NC(CC(C)C)C(=O)NC(CCSC)C(=O)NC(C(C)C)C(=O)NCC(=O)NCC(=O)NC(C(C)C)C(=O)NC(C(C)C)C(=O)O)NC(=O)C(C)NC(=O)CNC(=O)C(CCCCN)NC(=O)C(CC(=O)N)NC(=O)C(CO)NC(=O)CNC(=O)C(C(C)C)NC(=O)C(CC(=O)O)NC(=O)C(CCC(=O)O)NC(=O)C(C)NC(=O)C(Cc1ccccc1)NC(=O)C(Cc2ccccc2)NC(=O)C(C(C)C)NC(=O)C(CC(C)C)NC(=O)C(CCCCN)NC(=O)C(CCC(=O)N)NC(=O)C(Cc3c[nH]cn3)NC(=O)C(Cc4c[nH]cn4)NC(=O)C(C(C)C)NC(=O)C(CCC(=O)O)NC(=O)C(Cc5ccc(cc5)O)NC(=O)CNC(=O)C(CO)NC(=O)C(CC(=O)O)NC(=O)C(Cc6c[nH]cn6)NC(=O)C(CCCNC(=N)N)NC(=O)C(Cc7ccccc7)NC(=O)C(CCC(=O)O)NC(=O)C(C)NC(=O)C(CC(=O)O)N

" Ambient -20°C 5% Acetic Acid "Hu J, el-Fakahany EE.  Neuroreport.  4(6):760-762 (1993).Jia J, Kang L, Li S, et al. Amelioratory effects of testosterone treatment on cognitive performance deficits induced by soluble Aβ1-42 oligomers injected into the hippocampus. Horm Behav. 2013 Aug;64(3):477-86. PMID: 23954394.

 

Yin YI, Bassit B, Zhu L, et al. gamma-Secretase Substrate Concentration Modulates the Abeta42/Abeta40 Ratio: Implications for Alzheimer Disease. J Biol Chem. 2007 Aug 10;282(32):23639-44. PMID: 17556361.

 

Hartmann T, Bieger SC, Brühl B, et al. Distinct sites of intracellular production for Alzheimer's disease A beta40/42 amyloid peptides. Nat Med. 1997 Sep;3(9):1016-20. PMID: 9288729.

" Not dangerous goods.

LKT A4851 β-Amyloid Peptide (1-40), rat 1 mg 672.2 Endogenous APP peptide cleavage product, primary component in amyloid plaques typical of Alzheimer’s disease. Amyloid-β (1-40) 131438-79-4 ≥95% 4233.81 C190H291N51O57S1 "CCC(C)C(C(=O)NC(C(C)CC)C(=O)NCC(=O)NC(CC(C)C)C(=O)NC(CCSC)C(=O)NC(C(C)C)C(=O)NCC(=O)NCC(=O)NC(C(C)C)C(=O)NC(C(C)C)C(=O)O)NC(=O)C(C)NC(=O)CNC(=O)C(CCCCN)NC(=O)C(CC(=O)N)NC(=O)C(CO)NC(=O)CNC(=O)C(C(C)C)NC(=O)C(CC(=O)O)NC(=O)C(CCC(=O)O)NC(=O)C(C)NC(=O)C(Cc1ccccc1)NC(=O)C(Cc2ccccc2)NC(=O)C(C(C)C)NC(=O)C(CC(C)C)NC(=O)C(CCCCN)NC(=O)C(CCC(=O)N)NC(=O)C(Cc3c[nH]cn3)NC(=O)C(Cc4c[nH]cn4)NC(=O)C(C(C)C)NC(=O)C(CCC(=O)O)NC(=O)C(Cc5ccc(cc5)O)NC(=O)CNC(=O)C(CO)NC(=O)C(CC(=O)O)NC(=O)C(Cc6c[nH]cn6)NC(=O)C(CCCNC(=N)N)NC(=O)C(Cc7ccccc7)NC(=O)C(CCC(=O)O)NC(=O)C(C)NC(=O)C(CC(=O)O)N

" Ambient -20°C 5% Acetic Acid "Hu J, el-Fakahany EE.  Neuroreport.  4(6):760-762 (1993).Jia J, Kang L, Li S, et al. Amelioratory effects of testosterone treatment on cognitive performance deficits induced by soluble Aβ1-42 oligomers injected into the hippocampus. Horm Behav. 2013 Aug;64(3):477-86. PMID: 23954394.

 

Yin YI, Bassit B, Zhu L, et al. gamma-Secretase Substrate Concentration Modulates the Abeta42/Abeta40 Ratio: Implications for Alzheimer Disease. J Biol Chem. 2007 Aug 10;282(32):23639-44. PMID: 17556361.

 

Hartmann T, Bieger SC, Brühl B, et al. Distinct sites of intracellular production for Alzheimer's disease A beta40/42 amyloid peptides. Nat Med. 1997 Sep;3(9):1016-20. PMID: 9288729.

" Not dangerous goods.

LKT A4851 β-Amyloid Peptide (1-40), rat 2.5 mg 1188.1 Endogenous APP peptide cleavage product, primary component in amyloid plaques typical of Alzheimer’s disease. Amyloid-β (1-40) 131438-79-4 ≥95% 4233.81 C190H291N51O57S1 "CCC(C)C(C(=O)NC(C(C)CC)C(=O)NCC(=O)NC(CC(C)C)C(=O)NC(CCSC)C(=O)NC(C(C)C)C(=O)NCC(=O)NCC(=O)NC(C(C)C)C(=O)NC(C(C)C)C(=O)O)NC(=O)C(C)NC(=O)CNC(=O)C(CCCCN)NC(=O)C(CC(=O)N)NC(=O)C(CO)NC(=O)CNC(=O)C(C(C)C)NC(=O)C(CC(=O)O)NC(=O)C(CCC(=O)O)NC(=O)C(C)NC(=O)C(Cc1ccccc1)NC(=O)C(Cc2ccccc2)NC(=O)C(C(C)C)NC(=O)C(CC(C)C)NC(=O)C(CCCCN)NC(=O)C(CCC(=O)N)NC(=O)C(Cc3c[nH]cn3)NC(=O)C(Cc4c[nH]cn4)NC(=O)C(C(C)C)NC(=O)C(CCC(=O)O)NC(=O)C(Cc5ccc(cc5)O)NC(=O)CNC(=O)C(CO)NC(=O)C(CC(=O)O)NC(=O)C(Cc6c[nH]cn6)NC(=O)C(CCCNC(=N)N)NC(=O)C(Cc7ccccc7)NC(=O)C(CCC(=O)O)NC(=O)C(C)NC(=O)C(CC(=O)O)N

" Ambient -20°C 5% Acetic Acid "Hu J, el-Fakahany EE.  Neuroreport.  4(6):760-762 (1993).Jia J, Kang L, Li S, et al. Amelioratory effects of testosterone treatment on cognitive performance deficits induced by soluble Aβ1-42 oligomers injected into the hippocampus. Horm Behav. 2013 Aug;64(3):477-86. PMID: 23954394.

 

Yin YI, Bassit B, Zhu L, et al. gamma-Secretase Substrate Concentration Modulates the Abeta42/Abeta40 Ratio: Implications for Alzheimer Disease. J Biol Chem. 2007 Aug 10;282(32):23639-44. PMID: 17556361.

 

Hartmann T, Bieger SC, Brühl B, et al. Distinct sites of intracellular production for Alzheimer's disease A beta40/42 amyloid peptides. Nat Med. 1997 Sep;3(9):1016-20. PMID: 9288729.

" Not dangerous goods.

LKT A4852 β-Amyloid Peptide (1-40) 0.5 mg 396.1 Endogenous APP peptide cleavage product, primary component in amyloid plaques typical of Alzheimer’s disease. Amyloid-β ≥95% 4329.9 C194H295N53O58S1 Ambient -20°C "Jia J, Kang L, Li S, et al. Amelioratory effects of testosterone treatment on cognitive performance deficits induced by soluble Aβ1-42 oligomers injected into the hippocampus. Horm Behav. 2013 Aug;64(3):477-86. PMID: 23954394.

 

Yin YI, Bassit B, Zhu L, et al. gamma-Secretase Substrate Concentration Modulates the Abeta42/Abeta40 Ratio: Implications for Alzheimer Disease. J Biol Chem. 2007 Aug 10;282(32):23639-44. PMID: 17556361.

 

Hartmann T, Bieger SC, Brühl B, et al. Distinct sites of intracellular production for Alzheimer's disease A beta40/42 amyloid peptides. Nat Med. 1997 Sep;3(9):1016-20. PMID: 9288729.

" Not dangerous goods.

LKT A4852 β-Amyloid Peptide (1-40) 1 mg 672.2 Endogenous APP peptide cleavage product, primary component in amyloid plaques typical of Alzheimer’s disease. Amyloid-β ≥95% 4329.9 C194H295N53O58S1 Ambient -20°C "Jia J, Kang L, Li S, et al. Amelioratory effects of testosterone treatment on cognitive performance deficits induced by soluble Aβ1-42 oligomers injected into the hippocampus. Horm Behav. 2013 Aug;64(3):477-86. PMID: 23954394.

 

Yin YI, Bassit B, Zhu L, et al. gamma-Secretase Substrate Concentration Modulates the Abeta42/Abeta40 Ratio: Implications for Alzheimer Disease. J Biol Chem. 2007 Aug 10;282(32):23639-44. PMID: 17556361.

 

Hartmann T, Bieger SC, Brühl B, et al. Distinct sites of intracellular production for Alzheimer's disease A beta40/42 amyloid peptides. Nat Med. 1997 Sep;3(9):1016-20. PMID: 9288729.

" Not dangerous goods.

LKT A4852 β-Amyloid Peptide (1-40) 2.5 mg 1188.1 Endogenous APP peptide cleavage product, primary component in amyloid plaques typical of Alzheimer’s disease. Amyloid-β ≥95% 4329.9 C194H295N53O58S1 Ambient -20°C "Jia J, Kang L, Li S, et al. Amelioratory effects of testosterone treatment on cognitive performance deficits induced by soluble Aβ1-42 oligomers injected into the hippocampus. Horm Behav. 2013 Aug;64(3):477-86. PMID: 23954394.

 

Yin YI, Bassit B, Zhu L, et al. gamma-Secretase Substrate Concentration Modulates the Abeta42/Abeta40 Ratio: Implications for Alzheimer Disease. J Biol Chem. 2007 Aug 10;282(32):23639-44. PMID: 17556361.

 

Hartmann T, Bieger SC, Brühl B, et al. Distinct sites of intracellular production for Alzheimer's disease A beta40/42 amyloid peptides. Nat Med. 1997 Sep;3(9):1016-20. PMID: 9288729.

" Not dangerous goods.

LKT A4853 β-Amyloid Peptide (1-42), human 0.5 mg 396.1 Endogenous APP peptide cleavage product, primary component in amyloid plaques typical of Alzheimer’s disease. Amyloid-β (1-42) ≥95% 4550.18 C203H311N55O60S1 Ambient -20°C "Jia J, Kang L, Li S, et al. Amelioratory effects of testosterone treatment on cognitive performance deficits induced by soluble Aβ1-42 oligomers injected into the hippocampus. Horm Behav. 2013 Aug;64(3):477-86. PMID: 23954394.

 

Yin YI, Bassit B, Zhu L, et al. gamma-Secretase Substrate Concentration Modulates the Abeta42/Abeta40 Ratio: Implications for Alzheimer Disease. J Biol Chem. 2007 Aug 10;282(32):23639-44. PMID: 17556361.

 

Hartmann T, Bieger SC, Brühl B, et al. Distinct sites of intracellular production for Alzheimer's disease A beta40/42 amyloid peptides. Nat Med. 1997 Sep;3(9):1016-20. PMID: 9288729.

" Not dangerous goods.

LKT A4853 β-Amyloid Peptide (1-42), human 1 mg 672.2 Endogenous APP peptide cleavage product, primary component in amyloid plaques typical of Alzheimer’s disease. Amyloid-β (1-42) ≥95% 4550.18 C203H311N55O60S1 Ambient -20°C "Jia J, Kang L, Li S, et al. Amelioratory effects of testosterone treatment on cognitive performance deficits induced by soluble Aβ1-42 oligomers injected into the hippocampus. Horm Behav. 2013 Aug;64(3):477-86. PMID: 23954394.

 

Yin YI, Bassit B, Zhu L, et al. gamma-Secretase Substrate Concentration Modulates the Abeta42/Abeta40 Ratio: Implications for Alzheimer Disease. J Biol Chem. 2007 Aug 10;282(32):23639-44. PMID: 17556361.

 

Hartmann T, Bieger SC, Brühl B, et al. Distinct sites of intracellular production for Alzheimer's disease A beta40/42 amyloid peptides. Nat Med. 1997 Sep;3(9):1016-20. PMID: 9288729.

" Not dangerous goods.

LKT A4853 β-Amyloid Peptide (1-42), human 2.5 mg 1188.1 Endogenous APP peptide cleavage product, primary component in amyloid plaques typical of Alzheimer’s disease. Amyloid-β (1-42) ≥95% 4550.18 C203H311N55O60S1 Ambient -20°C "Jia J, Kang L, Li S, et al. Amelioratory effects of testosterone treatment on cognitive performance deficits induced by soluble Aβ1-42 oligomers injected into the hippocampus. Horm Behav. 2013 Aug;64(3):477-86. PMID: 23954394.

 

Yin YI, Bassit B, Zhu L, et al. gamma-Secretase Substrate Concentration Modulates the Abeta42/Abeta40 Ratio: Implications for Alzheimer Disease. J Biol Chem. 2007 Aug 10;282(32):23639-44. PMID: 17556361.

 

Hartmann T, Bieger SC, Brühl B, et al. Distinct sites of intracellular production for Alzheimer's disease A beta40/42 amyloid peptides. Nat Med. 1997 Sep;3(9):1016-20. PMID: 9288729.

" Not dangerous goods.

LKT A4854 β-Amyloid Peptide (1-42), rat 1 mg 444 Endogenous APP peptide cleavage product, primary component in amyloid plaques typical of Alzheimer’s disease. Amyloid-β (1-42) 107761-42-2 ≥95% 4454.09 C199H307N53O59S1 "CCC(C)C(C(=O)NC(C(C)CC)C(=O)NCC(=O)NC(CC(C)C)C(=O)NC(CCSC)C(=O)NC(C(C)C)C(=O)NCC(=O)NCC(=O)NC(C(C)C)C(=O)NC(C(C)C)C(=O)NC(C(C)CC)C(=O)NC(C)C(=O)O)NC(=O)C(C)NC(=O)CNC(=O)C(CCCCN)NC(=O)C(CC(=O)N)NC(=O)C(CO)NC(=O)CNC(=O)C(C(C)C)NC(=O)C(CC(=O)O)NC(=O)C(CCC(=O)O)NC(=O)C(C)NC(=O)C(Cc1ccccc1)NC(=O)C(Cc2ccccc2)NC(=O)C(C(C)C)NC(=O)C(CC(C)C)NC(=O)C(CCCCN)NC(=O)C(CCC(=O)N)NC(=O)C(Cc3c[nH]cn3)NC(=O)C(Cc4c[nH]cn4)NC(=O)C(C(C)C)NC(=O)C(CCC(=O)O)NC(=O)C(Cc5ccc(cc5)O)NC(=O)CNC(=O)C(CO)NC(=O)C(CC(=O)O)NC(=O)C(Cc6c[nH]cn6)NC(=O)C(CCCNC(=N)N)NC(=O)C(Cc7ccccc7)NC(=O)C(CCC(=O)O)NC(=O)C(C)NC(=O)C(CC(=O)O)N

" Ambient -20°C "Jia J, Kang L, Li S, et al. Amelioratory effects of testosterone treatment on cognitive performance deficits induced by soluble Aβ1-42 oligomers injected into the hippocampus. Horm Behav. 2013 Aug;64(3):477-86. PMID: 23954394.

 

Yin YI, Bassit B, Zhu L, et al. gamma-Secretase Substrate Concentration Modulates the Abeta42/Abeta40 Ratio: Implications for Alzheimer Disease. J Biol Chem. 2007 Aug 10;282(32):23639-44. PMID: 17556361.

 

Hartmann T, Bieger SC, Brühl B, et al. Distinct sites of intracellular production for Alzheimer's disease A beta40/42 amyloid peptides. Nat Med. 1997 Sep;3(9):1016-20. PMID: 9288729.

" Not dangerous goods.

LKT A4854 β-Amyloid Peptide (1-42), rat 2 mg 756.2 Endogenous APP peptide cleavage product, primary component in amyloid plaques typical of Alzheimer’s disease. Amyloid-β (1-42) 107761-42-2 ≥95% 4454.09 C199H307N53O59S1 "CCC(C)C(C(=O)NC(C(C)CC)C(=O)NCC(=O)NC(CC(C)C)C(=O)NC(CCSC)C(=O)NC(C(C)C)C(=O)NCC(=O)NCC(=O)NC(C(C)C)C(=O)NC(C(C)C)C(=O)NC(C(C)CC)C(=O)NC(C)C(=O)O)NC(=O)C(C)NC(=O)CNC(=O)C(CCCCN)NC(=O)C(CC(=O)N)NC(=O)C(CO)NC(=O)CNC(=O)C(C(C)C)NC(=O)C(CC(=O)O)NC(=O)C(CCC(=O)O)NC(=O)C(C)NC(=O)C(Cc1ccccc1)NC(=O)C(Cc2ccccc2)NC(=O)C(C(C)C)NC(=O)C(CC(C)C)NC(=O)C(CCCCN)NC(=O)C(CCC(=O)N)NC(=O)C(Cc3c[nH]cn3)NC(=O)C(Cc4c[nH]cn4)NC(=O)C(C(C)C)NC(=O)C(CCC(=O)O)NC(=O)C(Cc5ccc(cc5)O)NC(=O)CNC(=O)C(CO)NC(=O)C(CC(=O)O)NC(=O)C(Cc6c[nH]cn6)NC(=O)C(CCCNC(=N)N)NC(=O)C(Cc7ccccc7)NC(=O)C(CCC(=O)O)NC(=O)C(C)NC(=O)C(CC(=O)O)N

" Ambient -20°C "Jia J, Kang L, Li S, et al. Amelioratory effects of testosterone treatment on cognitive performance deficits induced by soluble Aβ1-42 oligomers injected into the hippocampus. Horm Behav. 2013 Aug;64(3):477-86. PMID: 23954394.

 

Yin YI, Bassit B, Zhu L, et al. gamma-Secretase Substrate Concentration Modulates the Abeta42/Abeta40 Ratio: Implications for Alzheimer Disease. J Biol Chem. 2007 Aug 10;282(32):23639-44. PMID: 17556361.

 

Hartmann T, Bieger SC, Brühl B, et al. Distinct sites of intracellular production for Alzheimer's disease A beta40/42 amyloid peptides. Nat Med. 1997 Sep;3(9):1016-20. PMID: 9288729.

" Not dangerous goods.

LKT A4854 β-Amyloid Peptide (1-42), rat 5 mg 1332 Endogenous APP peptide cleavage product, primary component in amyloid plaques typical of Alzheimer’s disease. Amyloid-β (1-42) 107761-42-2 ≥95% 4454.09 C199H307N53O59S1 "CCC(C)C(C(=O)NC(C(C)CC)C(=O)NCC(=O)NC(CC(C)C)C(=O)NC(CCSC)C(=O)NC(C(C)C)C(=O)NCC(=O)NCC(=O)NC(C(C)C)C(=O)NC(C(C)C)C(=O)NC(C(C)CC)C(=O)NC(C)C(=O)O)NC(=O)C(C)NC(=O)CNC(=O)C(CCCCN)NC(=O)C(CC(=O)N)NC(=O)C(CO)NC(=O)CNC(=O)C(C(C)C)NC(=O)C(CC(=O)O)NC(=O)C(CCC(=O)O)NC(=O)C(C)NC(=O)C(Cc1ccccc1)NC(=O)C(Cc2ccccc2)NC(=O)C(C(C)C)NC(=O)C(CC(C)C)NC(=O)C(CCCCN)NC(=O)C(CCC(=O)N)NC(=O)C(Cc3c[nH]cn3)NC(=O)C(Cc4c[nH]cn4)NC(=O)C(C(C)C)NC(=O)C(CCC(=O)O)NC(=O)C(Cc5ccc(cc5)O)NC(=O)CNC(=O)C(CO)NC(=O)C(CC(=O)O)NC(=O)C(Cc6c[nH]cn6)NC(=O)C(CCCNC(=N)N)NC(=O)C(Cc7ccccc7)NC(=O)C(CCC(=O)O)NC(=O)C(C)NC(=O)C(CC(=O)O)N

" Ambient -20°C "Jia J, Kang L, Li S, et al. Amelioratory effects of testosterone treatment on cognitive performance deficits induced by soluble Aβ1-42 oligomers injected into the hippocampus. Horm Behav. 2013 Aug;64(3):477-86. PMID: 23954394.

 

Yin YI, Bassit B, Zhu L, et al. gamma-Secretase Substrate Concentration Modulates the Abeta42/Abeta40 Ratio: Implications for Alzheimer Disease. J Biol Chem. 2007 Aug 10;282(32):23639-44. PMID: 17556361.

 

Hartmann T, Bieger SC, Brühl B, et al. Distinct sites of intracellular production for Alzheimer's disease A beta40/42 amyloid peptides. Nat Med. 1997 Sep;3(9):1016-20. PMID: 9288729.

" Not dangerous goods.

LKT A4930 7-Aminoactinomycin D 1 mg 122.6 Actinomycin derivative used to study apoptosis and phagocytosis. 2,7-diamino-4,6-dimethyl-3-oxo-N,N'-bis[7,11,14-trimethyl-2,5,9,12,15-pentaoxo-3,10-di(propan-2-yl)-8-oxa-1,4,11,14-tetrazabicyclo[14.3.0]nonadecan-6-yl]phenoxazine-1,9-dicarboxamide "7-Amino-Actinomycin D

7-amino-AMD

Actinomycin D, 7-amino-" 7240-37-1 ≥97% 1270.43 C62H87N13O16 CC1C(C(=O)NC(C(=O)N2CCCC2C(=O)N(CC(=O)N(C(C(=O)O1)C(C)C)C)C)C(C)C)NC(=O)C3=CC(=C(C4=C3N=C5C(=C(C(=O)C(=C5O4)C)N)C(=O)NC6C(OC(=O)C(N(C(=O)CN(C(=O)C7CCCN7C(=O)C(NC6=O)C(C)C)C)C)C(C)C)C)C)N Ambient 4°C Soluble in ethanol "Su YJ, Cheng TT, Chen CJ, et al. The association among leukocyte apoptosis, autoantibodies and disease severity in systemic lupus erythematosus. J Transl Med. 2013 Oct 19;11:261. PMID: 24138706.

 

Ortega E, Algarra I, Serrano MJ, et al. The use of 7-amino-actinomycin D in the analysis of Candida albicans phagocytosis and opsonization. J Immunol Methods. 2001 Jul 1;253(1-2):189-93. PMID: 11384680.

 

Philpott NJ, Turner AJ, Scopes J, et al. The use of 7-amino actinomycin D in identifying apoptosis: simplicity of use and broad spectrum of application compared with other techniques. Blood. 1996 Mar 15;87(6):2244-51. PMID: 8630384.

" T+, Xi "UN number: 3462     Class: 6.1     Packing Group: II

Proper shipping name: Toxins, extracted from living sources, solid, n.o.s. (7-Aminoactinomycin D)

Poison hazard:  No"

LKT A4930 7-Aminoactinomycin D 5 mg 613.7 Actinomycin derivative used to study apoptosis and phagocytosis. 2,7-diamino-4,6-dimethyl-3-oxo-N,N'-bis[7,11,14-trimethyl-2,5,9,12,15-pentaoxo-3,10-di(propan-2-yl)-8-oxa-1,4,11,14-tetrazabicyclo[14.3.0]nonadecan-6-yl]phenoxazine-1,9-dicarboxamide "7-Amino-Actinomycin D

7-amino-AMD

Actinomycin D, 7-amino-" 7240-37-1 ≥97% 1270.43 C62H87N13O16 CC1C(C(=O)NC(C(=O)N2CCCC2C(=O)N(CC(=O)N(C(C(=O)O1)C(C)C)C)C)C(C)C)NC(=O)C3=CC(=C(C4=C3N=C5C(=C(C(=O)C(=C5O4)C)N)C(=O)NC6C(OC(=O)C(N(C(=O)CN(C(=O)C7CCCN7C(=O)C(NC6=O)C(C)C)C)C)C(C)C)C)C)N Ambient 4°C Soluble in ethanol "Su YJ, Cheng TT, Chen CJ, et al. The association among leukocyte apoptosis, autoantibodies and disease severity in systemic lupus erythematosus. J Transl Med. 2013 Oct 19;11:261. PMID: 24138706.

 

Ortega E, Algarra I, Serrano MJ, et al. The use of 7-amino-actinomycin D in the analysis of Candida albicans phagocytosis and opsonization. J Immunol Methods. 2001 Jul 1;253(1-2):189-93. PMID: 11384680.

 

Philpott NJ, Turner AJ, Scopes J, et al. The use of 7-amino actinomycin D in identifying apoptosis: simplicity of use and broad spectrum of application compared with other techniques. Blood. 1996 Mar 15;87(6):2244-51. PMID: 8630384.

" T+, Xi "UN number: 3462     Class: 6.1     Packing Group: II

Proper shipping name: Toxins, extracted from living sources, solid, n.o.s. (7-Aminoactinomycin D)

Poison hazard:  No"

LKT A4931 3-Aminobenzamide 100 mg 52.3 PARP inhibitor. 3-aminobenzamide 3-AB; 3-ABA, INO-1001 3544-24-9 ≥97% 136.15 C7H8N2O C1=CC(=CC(=C1)N)C(=O)N Ambient 4°C Soluble in DMSO or ethanol. "Lakatos P, Szabó É, Hegedűs C, et al. 3-Aminobenzamide protects primary human keratinocytes from UV-induced cell death by a poly(ADP-ribosyl)ation independent mechanism. Biochim Biophys Acta. 2013 Mar;1833(3):743-51. PMID: 23246565.

 

Huang D, Wang Y, Wang L, et al. Poly(ADP-ribose) polymerase 1 is indispensable for transforming growth factor-β Induced Smad3 activation in vascular smooth muscle cell. PLoS One. 2011;6(10):e27123. PMID: 22073128.

 

Xie JJ, Yu X, Liao YH, et al. Poly (ADP-Ribose) polymerase inhibition attenuates atherosclerotic plaque development in ApoE-/- mice with hyperhomocysteinemia. J Atheroscler Thromb. 2009 Oct;16(5):641-53. PMID: 19776495.

 

De Blasio A, Messina C, Santulli A, et al. Differentiative pathway activated by 3-aminobenzamide, an inhibitor of PARP, in human osteosarcoma MG-63 cells. FEBS Lett. 2005 Jan 31;579(3):615-20. PMID: 15670817.

" Xi Not dangerous goods.

LKT A4931 3-Aminobenzamide 250 mg 112.1 PARP inhibitor. 3-aminobenzamide 3-AB; 3-ABA, INO-1001 3544-24-9 ≥97% 136.15 C7H8N2O C1=CC(=CC(=C1)N)C(=O)N Ambient 4°C Soluble in DMSO or ethanol. "Lakatos P, Szabó É, Hegedűs C, et al. 3-Aminobenzamide protects primary human keratinocytes from UV-induced cell death by a poly(ADP-ribosyl)ation independent mechanism. Biochim Biophys Acta. 2013 Mar;1833(3):743-51. PMID: 23246565.

 

Huang D, Wang Y, Wang L, et al. Poly(ADP-ribose) polymerase 1 is indispensable for transforming growth factor-β Induced Smad3 activation in vascular smooth muscle cell. PLoS One. 2011;6(10):e27123. PMID: 22073128.

 

Xie JJ, Yu X, Liao YH, et al. Poly (ADP-Ribose) polymerase inhibition attenuates atherosclerotic plaque development in ApoE-/- mice with hyperhomocysteinemia. J Atheroscler Thromb. 2009 Oct;16(5):641-53. PMID: 19776495.

 

De Blasio A, Messina C, Santulli A, et al. Differentiative pathway activated by 3-aminobenzamide, an inhibitor of PARP, in human osteosarcoma MG-63 cells. FEBS Lett. 2005 Jan 31;579(3):615-20. PMID: 15670817.

" Xi Not dangerous goods.

LKT A4931 3-Aminobenzamide 500 mg 149.5 PARP inhibitor. 3-aminobenzamide 3-AB; 3-ABA, INO-1001 3544-24-9 ≥97% 136.15 C7H8N2O C1=CC(=CC(=C1)N)C(=O)N Ambient 4°C Soluble in DMSO or ethanol. "Lakatos P, Szabó É, Hegedűs C, et al. 3-Aminobenzamide protects primary human keratinocytes from UV-induced cell death by a poly(ADP-ribosyl)ation independent mechanism. Biochim Biophys Acta. 2013 Mar;1833(3):743-51. PMID: 23246565.

 

Huang D, Wang Y, Wang L, et al. Poly(ADP-ribose) polymerase 1 is indispensable for transforming growth factor-β Induced Smad3 activation in vascular smooth muscle cell. PLoS One. 2011;6(10):e27123. PMID: 22073128.

 

Xie JJ, Yu X, Liao YH, et al. Poly (ADP-Ribose) polymerase inhibition attenuates atherosclerotic plaque development in ApoE-/- mice with hyperhomocysteinemia. J Atheroscler Thromb. 2009 Oct;16(5):641-53. PMID: 19776495.

 

De Blasio A, Messina C, Santulli A, et al. Differentiative pathway activated by 3-aminobenzamide, an inhibitor of PARP, in human osteosarcoma MG-63 cells. FEBS Lett. 2005 Jan 31;579(3):615-20. PMID: 15670817.

" Xi Not dangerous goods.

LKT A4933 Amifostine Trihydrate 50 mg 61.1 Thiol prodrug, antioxidant. "Ethanethiol, 2-((3-aminopropyl)amino)-, dihydrogen

phosphate (ester), trihydrate" Ethiofos; Gammaphos; SAPEP; Ethyol 112901-68-5 ≥98% 268.27 C5H15N2O3PS 3H2O C(CN)CNCCSP(=O)(O)O Ambient Ambient Soluble in water. "Chen C, Tian L, Zhang M, et al. Protective effect of amifostine on high-dose methotrexate-induced small intestinal mucositis in mice. Dig Dis Sci. 2013 Nov;58(11):3134-43. PMID: 23979434.

 

Lv W, Zhang M, Zhang Z, et al. Amifostine acts upon mitochondria to stimulate growth of bone marrow and regulate cytokines. Adv Exp Med Biol. 2013;789:195-201. PMID: 23852495.

 

Wozniak K, Gloc E, Morawiec Z, et al. Amifostine can differentially modulate DNA double-strand breaks and apoptosis induced by idarubicin in normal and cancer cells. Exp Oncol. 2008 Mar;30(1):22-8. PMID: 18438337.

 

Kouvaris JR, Kouloulias VE, Vlahos LJ. Amifostine: the first selective-target and broad-spectrum radioprotector. Oncologist. 2007 Jun;12(6):738-47. PMID: 17602063.

" Xn Not dangerous goods.

LKT A4933 Amifostine Trihydrate 100 mg 108.8 Thiol prodrug, antioxidant. "Ethanethiol, 2-((3-aminopropyl)amino)-, dihydrogen

phosphate (ester), trihydrate" Ethiofos; Gammaphos; SAPEP; Ethyol 112901-68-5 ≥98% 268.27 C5H15N2O3PS 3H2O C(CN)CNCCSP(=O)(O)O Ambient Ambient Soluble in water. "Chen C, Tian L, Zhang M, et al. Protective effect of amifostine on high-dose methotrexate-induced small intestinal mucositis in mice. Dig Dis Sci. 2013 Nov;58(11):3134-43. PMID: 23979434.

 

Lv W, Zhang M, Zhang Z, et al. Amifostine acts upon mitochondria to stimulate growth of bone marrow and regulate cytokines. Adv Exp Med Biol. 2013;789:195-201. PMID: 23852495.

 

Wozniak K, Gloc E, Morawiec Z, et al. Amifostine can differentially modulate DNA double-strand breaks and apoptosis induced by idarubicin in normal and cancer cells. Exp Oncol. 2008 Mar;30(1):22-8. PMID: 18438337.

 

Kouvaris JR, Kouloulias VE, Vlahos LJ. Amifostine: the first selective-target and broad-spectrum radioprotector. Oncologist. 2007 Jun;12(6):738-47. PMID: 17602063.

" Xn Not dangerous goods.

LKT A4933 Amifostine Trihydrate 500 mg 380.5 Thiol prodrug, antioxidant. "Ethanethiol, 2-((3-aminopropyl)amino)-, dihydrogen

phosphate (ester), trihydrate" Ethiofos; Gammaphos; SAPEP; Ethyol 112901-68-5 ≥98% 268.27 C5H15N2O3PS 3H2O C(CN)CNCCSP(=O)(O)O Ambient Ambient Soluble in water. "Chen C, Tian L, Zhang M, et al. Protective effect of amifostine on high-dose methotrexate-induced small intestinal mucositis in mice. Dig Dis Sci. 2013 Nov;58(11):3134-43. PMID: 23979434.

 

Lv W, Zhang M, Zhang Z, et al. Amifostine acts upon mitochondria to stimulate growth of bone marrow and regulate cytokines. Adv Exp Med Biol. 2013;789:195-201. PMID: 23852495.

 

Wozniak K, Gloc E, Morawiec Z, et al. Amifostine can differentially modulate DNA double-strand breaks and apoptosis induced by idarubicin in normal and cancer cells. Exp Oncol. 2008 Mar;30(1):22-8. PMID: 18438337.

 

Kouvaris JR, Kouloulias VE, Vlahos LJ. Amifostine: the first selective-target and broad-spectrum radioprotector. Oncologist. 2007 Jun;12(6):738-47. PMID: 17602063.

" Xn Not dangerous goods.

LKT A4935 6-Aminocaproic Acid 10 g 32.2 Protease inhibitor. 6-Aminohexanoic acid ε-Aminocaproic Acid; EACA; Amicar; Capracid; Epsikapron; Hemocaprol; Ipsilon 60-32-2 ≥98% 131.17 C6H13NO2 C(CCC(=O)O)CCN Ambient Ambient Soluble in water (330 mg/mL). DMSO 6 mg/mL. Insoluble in ethanol or chloroform. "Lindner J, Guenther J, Nick H, et al. Modulation of granule cell migration by a glia-derived protein. Proc Natl Acad Sci U S A. 1986 Jun;83(12):4568-71. PMID: 3459192.

 

Gardner FH, Helmer RE 3rd. Aminocaproic acid. Use in control of hemorrhage in patients with amegakaryocytic thrombocytopenia. JAMA. 1980 Jan 4;243(1):35-7. PMID: 6965311.

" Xi Not dangerous goods.

LKT A4935 6-Aminocaproic Acid 100 g 55.3 Protease inhibitor. 6-Aminohexanoic acid ε-Aminocaproic Acid; EACA; Amicar; Capracid; Epsikapron; Hemocaprol; Ipsilon 60-32-2 ≥98% 131.17 C6H13NO2 C(CCC(=O)O)CCN Ambient Ambient Soluble in water (330 mg/mL). DMSO 6 mg/mL. Insoluble in ethanol or chloroform. "Lindner J, Guenther J, Nick H, et al. Modulation of granule cell migration by a glia-derived protein. Proc Natl Acad Sci U S A. 1986 Jun;83(12):4568-71. PMID: 3459192.

 

Gardner FH, Helmer RE 3rd. Aminocaproic acid. Use in control of hemorrhage in patients with amegakaryocytic thrombocytopenia. JAMA. 1980 Jan 4;243(1):35-7. PMID: 6965311.

" Xi Not dangerous goods.

LKT A4940 6-Aminonicotinamide 1 g 101.9 G6PDH inhibitor. 6-Aminopyridine-3-carboxamide 6-Aminopyridine-3-carboxamide 329-89-5 ≥98% 137.14 C6H7N3O C1=CC(=NC=C1C(=O)N)N Ambient Ambient in MTOH, 0.2/20; clear after heating "Parkhitko AA, Priolo C, Coloff JL, et al. Autophagy-dependent metabolic reprogramming sensitizes TSC2-deficient cells to the antimetabolite 6-aminonicotinamide. Mol Cancer Res. 2014 Jan;12(1):48-57. PMID: 24296756.

 

Alvarez GM, Ferretti EL, Gutnisky C, et al. Modulation of glycolysis and the pentose phosphate pathway influences porcine oocyte in vitro maturation. Reprod Domest Anim. 2013 Aug;48(4):545-53. PMID: 23189959.

 

Preuss J, Richardson AD, Pinkerton A, et al. Identification and characterization of novel human glucose-6-phosphate dehydrogenase inhibitors. J Biomol Screen. 2013 Mar;18(3):286-97. PMID: 23023104.

 

Bhardwaj R, Sharma PK, Jadon SP, et al. A combination of 2-deoxy-D-glucose and 6-aminonicotinamide induces cell cycle arrest and apoptosis selectively in irradiated human malignant cells. Tumour Biol. 2012 Aug;33(4):1021-30. PMID: 22328137.

" T Not dangerous goods.

LKT A4940 6-Aminonicotinamide 5 g 407.7 G6PDH inhibitor. 6-Aminopyridine-3-carboxamide 6-Aminopyridine-3-carboxamide 329-89-5 ≥98% 137.14 C6H7N3O C1=CC(=NC=C1C(=O)N)N Ambient Ambient in MTOH, 0.2/20; clear after heating "Parkhitko AA, Priolo C, Coloff JL, et al. Autophagy-dependent metabolic reprogramming sensitizes TSC2-deficient cells to the antimetabolite 6-aminonicotinamide. Mol Cancer Res. 2014 Jan;12(1):48-57. PMID: 24296756.

 

Alvarez GM, Ferretti EL, Gutnisky C, et al. Modulation of glycolysis and the pentose phosphate pathway influences porcine oocyte in vitro maturation. Reprod Domest Anim. 2013 Aug;48(4):545-53. PMID: 23189959.

 

Preuss J, Richardson AD, Pinkerton A, et al. Identification and characterization of novel human glucose-6-phosphate dehydrogenase inhibitors. J Biomol Screen. 2013 Mar;18(3):286-97. PMID: 23023104.

 

Bhardwaj R, Sharma PK, Jadon SP, et al. A combination of 2-deoxy-D-glucose and 6-aminonicotinamide induces cell cycle arrest and apoptosis selectively in irradiated human malignant cells. Tumour Biol. 2012 Aug;33(4):1021-30. PMID: 22328137.

" T Not dangerous goods.

LKT A5001 Aminopterin 25 mg 172.8 Folic acid analog, derivative of pterin; dihydrofolate reductase inhibitor. "N-[4-[[(2,4-Diamino-6-pteridinyl)methyl]amino]benzoyl]-L-glutamic acid 

" 4-Aminofolic acid 54-62-6 ≥95% 440.41 C19H20N8O5 C1=CC(=CC=C1C(=O)NC(CCC(=O)O)C(=O)O)NCC2=CN=C3C(=N2)C(=NC(=N3)N)N Ambient Ambient Soluble in DMSO or 2 N NaOH (50mg/mL). "Visentin M, Zhao R, Goldman ID. The antifolates. Hematol Oncol Clin North Am. 2012 Jun;26(3):629-48. PMID: 22520983.

 

McGuire JJ. Anticancer antifolates: current status and future directions. Curr Pharm Des. 2003;9(31):2593-613. PMID: 14529544.

 

Baggott JE, Morgan SL, Ha TS, et al. Antifolates in rheumatoid arthritis: a hypothetical mechanism of action. Clin Exp Rheumatol. 1993 Mar-Apr;11 Suppl 8:S101-5. PMID: 8324932.

" Repr., T+ "UN number: 2811      Class: 6.1 Packing group: I 

Proper shipping name: Toxic solids, organic, n.o.s. (Aminopterin) 

Reportable Quantity (RQ): Marine pollutant: No Poison Inhalation Hazard: No"

LKT A5001 Aminopterin 100 mg 468.1 Folic acid analog, derivative of pterin; dihydrofolate reductase inhibitor. "N-[4-[[(2,4-Diamino-6-pteridinyl)methyl]amino]benzoyl]-L-glutamic acid 

" 4-Aminofolic acid 54-62-6 ≥95% 440.41 C19H20N8O5 C1=CC(=CC=C1C(=O)NC(CCC(=O)O)C(=O)O)NCC2=CN=C3C(=N2)C(=NC(=N3)N)N Ambient Ambient Soluble in DMSO or 2 N NaOH (50mg/mL). "Visentin M, Zhao R, Goldman ID. The antifolates. Hematol Oncol Clin North Am. 2012 Jun;26(3):629-48. PMID: 22520983.

 

McGuire JJ. Anticancer antifolates: current status and future directions. Curr Pharm Des. 2003;9(31):2593-613. PMID: 14529544.

 

Baggott JE, Morgan SL, Ha TS, et al. Antifolates in rheumatoid arthritis: a hypothetical mechanism of action. Clin Exp Rheumatol. 1993 Mar-Apr;11 Suppl 8:S101-5. PMID: 8324932.

" Repr., T+ "UN number: 2811      Class: 6.1 Packing group: I 

Proper shipping name: Toxic solids, organic, n.o.s. (Aminopterin) 

Reportable Quantity (RQ): Marine pollutant: No Poison Inhalation Hazard: No"

LKT A5001 Aminopterin 500 mg 1617.8 Folic acid analog, derivative of pterin; dihydrofolate reductase inhibitor. "N-[4-[[(2,4-Diamino-6-pteridinyl)methyl]amino]benzoyl]-L-glutamic acid 

" 4-Aminofolic acid 54-62-6 ≥95% 440.41 C19H20N8O5 C1=CC(=CC=C1C(=O)NC(CCC(=O)O)C(=O)O)NCC2=CN=C3C(=N2)C(=NC(=N3)N)N Ambient Ambient Soluble in DMSO or 2 N NaOH (50mg/mL). "Visentin M, Zhao R, Goldman ID. The antifolates. Hematol Oncol Clin North Am. 2012 Jun;26(3):629-48. PMID: 22520983.

 

McGuire JJ. Anticancer antifolates: current status and future directions. Curr Pharm Des. 2003;9(31):2593-613. PMID: 14529544.

 

Baggott JE, Morgan SL, Ha TS, et al. Antifolates in rheumatoid arthritis: a hypothetical mechanism of action. Clin Exp Rheumatol. 1993 Mar-Apr;11 Suppl 8:S101-5. PMID: 8324932.

" Repr., T+ "UN number: 2811      Class: 6.1 Packing group: I 

Proper shipping name: Toxic solids, organic, n.o.s. (Aminopterin) 

Reportable Quantity (RQ): Marine pollutant: No Poison Inhalation Hazard: No"

LKT A5032 D,L-Aminoglutethimide 500 mg 86.4 Aromatase inhibitor. 3-(4-Aminophenyl)-3-ethyl-2,6-piperidinedione Aminoglutethimide; Cytadren; Elipten; Orimeten 125-84-8 ≥98% 232.28 C13H16N2O2 CCC1(CCC(=O)NC1=O)C2=CC=C(C=C2)N Ambient -20°C Soluble in organic solvents except ethyl acetate and ethanol. Insoluble in water. "Pozza C, Graziadio C, Giannetta E, et al. Management Strategies for Aggressive Cushing's Syndrome: From Macroadenomas to Ectopics. J Oncol. 2012;2012:685213. PMID: 22934113.

 

Dubrovsky B. Natural steroids counteracting some actions of putative depressogenic steroids on the central nervous system: potential therapeutic benefits. Med Hypotheses. 1997 Jul;49(1):51-5. PMID: 9247908.

" Xi Not dangerous goods.

LKT A5032 D,L-Aminoglutethimide 1 g 144.1 Aromatase inhibitor. 3-(4-Aminophenyl)-3-ethyl-2,6-piperidinedione Aminoglutethimide; Cytadren; Elipten; Orimeten 125-84-8 ≥98% 232.28 C13H16N2O2 CCC1(CCC(=O)NC1=O)C2=CC=C(C=C2)N Ambient -20°C Soluble in organic solvents except ethyl acetate and ethanol. Insoluble in water. "Pozza C, Graziadio C, Giannetta E, et al. Management Strategies for Aggressive Cushing's Syndrome: From Macroadenomas to Ectopics. J Oncol. 2012;2012:685213. PMID: 22934113.

 

Dubrovsky B. Natural steroids counteracting some actions of putative depressogenic steroids on the central nervous system: potential therapeutic benefits. Med Hypotheses. 1997 Jul;49(1):51-5. PMID: 9247908.

" Xi Not dangerous goods.

LKT A5033 4-Aminosalicylic Acid 25 g 20.4 Dihydrofolate reductase inhibitor. 4-Amino-2-hydroxybenzoic acid p-Aminosalicylic Acid; PASER; Rezipas 65-49-6 ≥98% 153.14 C7H7NO3 C1=CC(=C(C=C1N)O)C(=O)O Ambient Ambient Soluble in water and alcohol. Practically insoluble in benzene.  "Dhaneshwar SS. Colon-specific prodrugs of 4-aminosalicylic acid for inflammatory bowel disease. World J Gastroenterol. 2014 Apr 7;20(13):3564-71. PMID: 24707139.

 

Jensen KA, Rosdahl KG, Ingvorsen H. Tuberculostatic derivatives of rho-aminobenzoic acid; esters and amides of 4-aminosalicylic acid. Acta Chem Scand. 1948;2(3):220-4. PMID: 18098531.

" Xn Not dangerous goods.

LKT A5033 4-Aminosalicylic Acid 100 g 29.9 Dihydrofolate reductase inhibitor. 4-Amino-2-hydroxybenzoic acid p-Aminosalicylic Acid; PASER; Rezipas 65-49-6 ≥98% 153.14 C7H7NO3 C1=CC(=C(C=C1N)O)C(=O)O Ambient Ambient Soluble in water and alcohol. Practically insoluble in benzene.  "Dhaneshwar SS. Colon-specific prodrugs of 4-aminosalicylic acid for inflammatory bowel disease. World J Gastroenterol. 2014 Apr 7;20(13):3564-71. PMID: 24707139.

 

Jensen KA, Rosdahl KG, Ingvorsen H. Tuberculostatic derivatives of rho-aminobenzoic acid; esters and amides of 4-aminosalicylic acid. Acta Chem Scand. 1948;2(3):220-4. PMID: 18098531.

" Xn Not dangerous goods.

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