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LKT Labs U5232Uniconazole Triazole

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LKT Labs 是一家专注于防癌抗癌特殊化学品研究和开发的公司。主要提供:癌症药物、药物发现试剂盒、天然产物、广泛的生命科学研究试剂、定制合成。
美国LKT Labs 是1988年在美国成立的,为全球提供先端的药物研发试剂、试剂盒、委托合成,并为药物生产企业提供原料,最近几年在农药、水产养殖业有很大程度的开发。LKT Labs U5232Uniconazole Triazole

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LKT Labs 是一家专注于防癌抗癌特殊化学品研究和开发的公司。主要提供:癌症药物、药物发现试剂盒、天然产物、广泛的生命科学研究试剂、定制合成。
美国LKT Labs 是1988年在美国成立的,为全球提供先端的药物研发试剂、试剂盒、委托合成,并为药物生产企业提供原料,最近几年在农药、水产养殖业有很大程度的开发。在LKT Labs 可以找到在其他地方找不到的产品。

LKT Labs U5232 Uniconazole Triazole

LKT Labs U5232 Uniconazole Triazole

 

LKT B8271 Bursin 25 mg 180 Tripeptide, adjuvant, induces B-cell differentiation. Bursopoietin; Lys-his-gly-NH2 60267-34-7 ≥95% 339.39 C14H25N7O3 C1=NC=NC1CC(C(=O)NCC(=O)N)NC(=O)C(CCCCN)N Ambient -20°C "Wang C, Wen WY, Su CX, et al. Bursin as an adjuvant is a potent enhancer of immune response in mice immunized with the JEV subunit vaccine. Vet Immunol Immunopathol. 2008 Apr 15;122(3-4):265-74. PMID: 18191231.

 

Otsubo Y, Chen N, Kajiwara E, et al. Role of bursin in the development of B lymphocytes in chicken embryonic Bursa of Fabricius. Dev Comp Immunol. 2001 Jun-Jul;25(5-6):485-93. PMID: 11356228.

"

LKT B8274 Buspirone Hydrochloride 1 g 69.3 Azapirone; α1-adrenergic and 5-HT1A partial agonist, D2/3/4 antagonist. 8-[4-[4-(2-Pyrimidinyl)=1=piperazinyl]butyl]-8-azaspiro[4.5]decane-7,9-dione hydrochloride Anisal; Axoren; Bespar; Buspinol; Narol 33386-08-2 ≥98% 421.97 C21H31N5O2 HCl C1CCC2(C1)CC(=O)N(C(=O)C2)CCCCN3CCN(CC3)C4=NC=CC=N4.Cl Ambient 4°C Soluble in water. "Navarrete A, Flores-Machorro FX, Téllez-Ballesteros RI, et al. Study on action mechanism of 1-(4-methoxy-2-methylphenyl)piperazine (MMPP) in acquisition, formation, and consolidation of memory in mice. Drug Dev Res. 2014 Mar;75(2):59-67. PMID: 24648132.

 

Loane C, Politis M. Buspirone: what is it all about? Brain Res. 2012 Jun 21;1461:111-8. PMID: 22608068.

" T "UN number: 2811     Class:  6.1     Packing group:  III

Proper shipping name:  Toxic solids, organic, n.o.s. (Buspirone hydrochloride)  Marine pollutant:  No     Poison inhalation hazard:  No"

LKT B8274 Buspirone Hydrochloride 5 g 231.1 Azapirone; α1-adrenergic and 5-HT1A partial agonist, D2/3/4 antagonist. 8-[4-[4-(2-Pyrimidinyl)=1=piperazinyl]butyl]-8-azaspiro[4.5]decane-7,9-dione hydrochloride Anisal; Axoren; Bespar; Buspinol; Narol 33386-08-2 ≥98% 421.97 C21H31N5O2 HCl C1CCC2(C1)CC(=O)N(C(=O)C2)CCCCN3CCN(CC3)C4=NC=CC=N4.Cl Ambient 4°C Soluble in water. "Navarrete A, Flores-Machorro FX, Téllez-Ballesteros RI, et al. Study on action mechanism of 1-(4-methoxy-2-methylphenyl)piperazine (MMPP) in acquisition, formation, and consolidation of memory in mice. Drug Dev Res. 2014 Mar;75(2):59-67. PMID: 24648132.

 

Loane C, Politis M. Buspirone: what is it all about? Brain Res. 2012 Jun 21;1461:111-8. PMID: 22608068.

" T "UN number: 2811     Class:  6.1     Packing group:  III

Proper shipping name:  Toxic solids, organic, n.o.s. (Buspirone hydrochloride)  Marine pollutant:  No     Poison inhalation hazard:  No"

LKT Z6269 Z-Pro-D-Leu 10 mg 120 Peptide fragment of oxytocin. Z-P-D-L ≥95% 362.4 C19H26N2O5 Ambient -20°C "Szabó G, Kovács GL, Székeli S, et al. C-terminal fragments of oxytocin (prolyl-leucyl-glycinamide and Z-prolyl-D-leucine) attenuate the development of tolerance to ethanol. Acta Physiol Hung. 1987;69(1):115-22. PMID: 2884803.

 

Kovács GL, Izbéki F, Horváth Z, et al. Effects of oxytocin and a derivative (Z-prolyl-D-leucine) on morphine tolerance/withdrawal are mediated by the limbic system. Behav Brain Res. 1984 Oct;14(1):1-8. PMID: 6542796.

 

Walter R, Ritzmann RF, Bhargava HN, et al. Inhibition by Z-Pro-D-Leu of development of tolerance to and physical dependence on morphine in mice. Proc Natl Acad Sci U S A. 1978 Sep;75(9):4573-6. PMID: 279936.

" Not dangerous goods.

LKT Z6269 Z-Pro-D-Leu 20 mg 204.1 Peptide fragment of oxytocin. Z-P-D-L ≥95% 362.4 C19H26N2O5 Ambient -20°C "Szabó G, Kovács GL, Székeli S, et al. C-terminal fragments of oxytocin (prolyl-leucyl-glycinamide and Z-prolyl-D-leucine) attenuate the development of tolerance to ethanol. Acta Physiol Hung. 1987;69(1):115-22. PMID: 2884803.

 

Kovács GL, Izbéki F, Horváth Z, et al. Effects of oxytocin and a derivative (Z-prolyl-D-leucine) on morphine tolerance/withdrawal are mediated by the limbic system. Behav Brain Res. 1984 Oct;14(1):1-8. PMID: 6542796.

 

Walter R, Ritzmann RF, Bhargava HN, et al. Inhibition by Z-Pro-D-Leu of development of tolerance to and physical dependence on morphine in mice. Proc Natl Acad Sci U S A. 1978 Sep;75(9):4573-6. PMID: 279936.

" Not dangerous goods.

LKT Z6269 Z-Pro-D-Leu 50 mg 359.9 Peptide fragment of oxytocin. Z-P-D-L ≥95% 362.4 C19H26N2O5 Ambient -20°C "Szabó G, Kovács GL, Székeli S, et al. C-terminal fragments of oxytocin (prolyl-leucyl-glycinamide and Z-prolyl-D-leucine) attenuate the development of tolerance to ethanol. Acta Physiol Hung. 1987;69(1):115-22. PMID: 2884803.

 

Kovács GL, Izbéki F, Horváth Z, et al. Effects of oxytocin and a derivative (Z-prolyl-D-leucine) on morphine tolerance/withdrawal are mediated by the limbic system. Behav Brain Res. 1984 Oct;14(1):1-8. PMID: 6542796.

 

Walter R, Ritzmann RF, Bhargava HN, et al. Inhibition by Z-Pro-D-Leu of development of tolerance to and physical dependence on morphine in mice. Proc Natl Acad Sci U S A. 1978 Sep;75(9):4573-6. PMID: 279936.

" Not dangerous goods.

LKT B8275 n-Butyric Acid 10 ml 51.8 Fatty acid found in dairy products; HDAC inhibitor. Butanoic acid; Butyric acid; Ethylacetic acid 107-92-6 ≥98% 88.1 C4H8O2 CCCC(=O)O Ambient Ambient Miscible with water, alcohol or ether. "Kim SW, Hooker JM, Otto N, et al. Whole-body pharmacokinetics of HDAC inhibitor drugs, butyric acid, valproic acid and 4-phenylbutyric acid measured with carbon-11 labeled analogs by PET. Nucl Med Biol. 2013 Oct;40(7):912-8. PMID: 23906667.

 

Inagaki A, Sakata T. Dose-dependent stimulatory and inhibitory effects of luminal and serosal n-butyric acid on epithelial cell proliferation of pig distal colonic mucosa. J Nutr Sci Vitaminol (Tokyo). 2005 Jun;51(3):156-60. PMID: 16161765.

 

Komata T, Kanzawa T, Nashimoto T, et al. Histone deacetylase inhibitors, N-butyric acid and trichostatin A, induce caspase-8- but not caspase-9-dependent apoptosis in human malignant glioma cells. Int J Oncol. 2005 May;26(5):1345-52. PMID: 15809727.

" Xi, C "UN number: 2820     Class: 8     Packing group: III

Proper shipping name:  Butyric acid

Reportable Quantity (RQ):  5000 lbs.     Poison inhalation hazard:  No."

LKT B8275 n-Butyric Acid 100 ml 72.2 Fatty acid found in dairy products; HDAC inhibitor. Butanoic acid; Butyric acid; Ethylacetic acid 107-92-6 ≥98% 88.1 C4H8O2 CCCC(=O)O Ambient Ambient Miscible with water, alcohol or ether. "Kim SW, Hooker JM, Otto N, et al. Whole-body pharmacokinetics of HDAC inhibitor drugs, butyric acid, valproic acid and 4-phenylbutyric acid measured with carbon-11 labeled analogs by PET. Nucl Med Biol. 2013 Oct;40(7):912-8. PMID: 23906667.

 

Inagaki A, Sakata T. Dose-dependent stimulatory and inhibitory effects of luminal and serosal n-butyric acid on epithelial cell proliferation of pig distal colonic mucosa. J Nutr Sci Vitaminol (Tokyo). 2005 Jun;51(3):156-60. PMID: 16161765.

 

Komata T, Kanzawa T, Nashimoto T, et al. Histone deacetylase inhibitors, N-butyric acid and trichostatin A, induce caspase-8- but not caspase-9-dependent apoptosis in human malignant glioma cells. Int J Oncol. 2005 May;26(5):1345-52. PMID: 15809727.

" Xi, C "UN number: 2820     Class: 8     Packing group: III

Proper shipping name:  Butyric acid

Reportable Quantity (RQ):  5000 lbs.     Poison inhalation hazard:  No."

LKT B8276 Butyric Acid Sodium 5 g 129 HDAC inhibitor, RNA splicing modulator. Sodium butyrate; Sodium butanoate 156-54-7 ≥97% 110.09 C4H7NaO2 CCCC(=O)[O-].[Na+] Hygroscopic Ambient Ambient Soluble in water. "Han A, Sung YB, Chung SY, et al. Possible additional antidepressant-like mechanism of sodium butyrate: targeting the hippocampus. Neuropharmacology. 2014 Jun;81:292-302. PMID: 24607816.

 

Mu D, Gao Z, Guo H, et al. Sodium butyrate induces growth inhibition and apoptosis in human prostate cancer DU145 cells by up-regulation of the expression of annexin A1. PLoS One. 2013 Sep 23;8(9):e74922. PMID: 24086397.

 

Berndt BE, Zhang M, Owyang SY, et al. Butyrate increases IL-23 production by stimulated dendritic cells. Am J Physiol Gastrointest Liver Physiol. 2012 Dec 15;303(12):G1384-92. PMID: 23086919.

 

Hnilicová J, Hozeifi S, Dušková E, et al. Histone deacetylase activity modulates alternative splicing. PLoS One. 2011 Feb 2;6(2):e16727.  PMID: 21311748." Xn Not dangerous goods.

LKT B8276 Butyric Acid Sodium 25 g 301.8 HDAC inhibitor, RNA splicing modulator. Sodium butyrate; Sodium butanoate 156-54-7 ≥97% 110.09 C4H7NaO2 CCCC(=O)[O-].[Na+] Hygroscopic Ambient Ambient Soluble in water. "Han A, Sung YB, Chung SY, et al. Possible additional antidepressant-like mechanism of sodium butyrate: targeting the hippocampus. Neuropharmacology. 2014 Jun;81:292-302. PMID: 24607816.

 

Mu D, Gao Z, Guo H, et al. Sodium butyrate induces growth inhibition and apoptosis in human prostate cancer DU145 cells by up-regulation of the expression of annexin A1. PLoS One. 2013 Sep 23;8(9):e74922. PMID: 24086397.

 

Berndt BE, Zhang M, Owyang SY, et al. Butyrate increases IL-23 production by stimulated dendritic cells. Am J Physiol Gastrointest Liver Physiol. 2012 Dec 15;303(12):G1384-92. PMID: 23086919.

 

Hnilicová J, Hozeifi S, Dušková E, et al. Histone deacetylase activity modulates alternative splicing. PLoS One. 2011 Feb 2;6(2):e16727.  PMID: 21311748." Xn Not dangerous goods.

LKT B8278 Butoconazole Nitrate 100 mg 50.2 Imidazole; 14-α demethylase inhibitor. 64872-77-1 ≥98% 474.79 C19H18Cl3N3O3S C1=CC(=C(C(=C1)Cl)SC(CCC2=CC=C(C=C2)Cl)CN3C=CN=C3)Cl.[N+](=O)(O)[O-] Ambient Ambient "Seidman LS, Skokos CK. An evaluation of butoconazole nitrate 2% site release vaginal cream (Gynazole-1) compared to fluconazole 150 mg tablets (Diflucan) in the time to relief of symptoms in patients with vulvovaginal candidiasis. Infect Dis Obstet Gynecol. 2005 Dec;13(4):197-206. PMID: 16338779.

 

Bourée P, Issoire C. In vitro evaluation of the activity of butoconazole against Trichomonas vaginalis. Pathol Biol (Paris). 1992 May;40(5):492-4. PMID: 1495832.

 

Hernández Molina JM, Llosá J, Martinez Brocal A, et al. In vitro activity of cloconazole, sulconazole, butoconazole, isoconazole, fenticonazole, and five other antifungal agents against clinical isolates of Candida albicans and Candida spp. Mycopathologia. 1992 Apr;118(1):15-21. PMID: 1406898.

" Not dangerous goods.

LKT B8278 Butoconazole Nitrate 250 mg 80.4 Imidazole; 14-α demethylase inhibitor. 64872-77-1 ≥98% 474.79 C19H18Cl3N3O3S C1=CC(=C(C(=C1)Cl)SC(CCC2=CC=C(C=C2)Cl)CN3C=CN=C3)Cl.[N+](=O)(O)[O-] Ambient Ambient "Seidman LS, Skokos CK. An evaluation of butoconazole nitrate 2% site release vaginal cream (Gynazole-1) compared to fluconazole 150 mg tablets (Diflucan) in the time to relief of symptoms in patients with vulvovaginal candidiasis. Infect Dis Obstet Gynecol. 2005 Dec;13(4):197-206. PMID: 16338779.

 

Bourée P, Issoire C. In vitro evaluation of the activity of butoconazole against Trichomonas vaginalis. Pathol Biol (Paris). 1992 May;40(5):492-4. PMID: 1495832.

 

Hernández Molina JM, Llosá J, Martinez Brocal A, et al. In vitro activity of cloconazole, sulconazole, butoconazole, isoconazole, fenticonazole, and five other antifungal agents against clinical isolates of Candida albicans and Candida spp. Mycopathologia. 1992 Apr;118(1):15-21. PMID: 1406898.

" Not dangerous goods.

LKT B8278 Butoconazole Nitrate 1 g 251.3 Imidazole; 14-α demethylase inhibitor. 64872-77-1 ≥98% 474.79 C19H18Cl3N3O3S C1=CC(=C(C(=C1)Cl)SC(CCC2=CC=C(C=C2)Cl)CN3C=CN=C3)Cl.[N+](=O)(O)[O-] Ambient Ambient "Seidman LS, Skokos CK. An evaluation of butoconazole nitrate 2% site release vaginal cream (Gynazole-1) compared to fluconazole 150 mg tablets (Diflucan) in the time to relief of symptoms in patients with vulvovaginal candidiasis. Infect Dis Obstet Gynecol. 2005 Dec;13(4):197-206. PMID: 16338779.

 

Bourée P, Issoire C. In vitro evaluation of the activity of butoconazole against Trichomonas vaginalis. Pathol Biol (Paris). 1992 May;40(5):492-4. PMID: 1495832.

 

Hernández Molina JM, Llosá J, Martinez Brocal A, et al. In vitro activity of cloconazole, sulconazole, butoconazole, isoconazole, fenticonazole, and five other antifungal agents against clinical isolates of Candida albicans and Candida spp. Mycopathologia. 1992 Apr;118(1):15-21. PMID: 1406898.

" Not dangerous goods.

LKT B8363 Bupropion Hydrochloride 50 mg 88.3 α3β2, α3β4, α4β2 nAChR antagonist, indirect DA and NE reuptake inhibitor. Wellbutrin 31677-93-7 ≥98% 276.2 C13H18ClNO HCl CC(C(=O)C1=CC(=CC=C1)Cl)NC(C)(C)C.Cl Ambient Ambient 50 mg/ml MeOH "Shah TH, Moradimehr A. Bupropion for the treatment of neuropathic pain. Am J Hosp Palliat Care. 2010 Aug;27(5):333-6. PMID: 20185402.

 

Arias HR. Is the inhibition of nicotinic acetylcholine receptors by bupropion involved in its clinical actions? Int J Biochem Cell Biol. 2009 Nov;41(11):2098-108. PMID: 19497387.

 

Li Z, Maglione M, Tu W, et al. Meta-analysis: pharmacologic treatment of obesity. Ann Intern Med. 2005 Apr 5;142(7):532-46. PMID: 15809465.

 

Miller DK, Sumithran SP, Dwoskin LP. Bupropion inhibits nicotine-evoked [(3)H]overflow from rat striatal slices preloaded with [(3)H]dopamine and from rat hippocampal slices preloaded with [(3)H]norepinephrine. J Pharmacol Exp Ther. 2002 Sep;302(3):1113-22. PMID: 12183670.

 

Dong J, Blier P. Modification of norepinephrine and serotonin, but not dopamine, neuron firing by sustained bupropion treatment. Psychopharmacology (Berl). 2001 Apr;155(1):52-7. PMID: 11374336.

 

Cantwell DP. ADHD through the life span: the role of bupropion in treatment. J Clin Psychiatry. 1998;59 Suppl 4:92-4. PMID: 9554326.

" Xn Not dangerous goods.

LKT B8363 Bupropion Hydrochloride 250 mg 237.8 α3β2, α3β4, α4β2 nAChR antagonist, indirect DA and NE reuptake inhibitor. Wellbutrin 31677-93-7 ≥98% 276.2 C13H18ClNO HCl CC(C(=O)C1=CC(=CC=C1)Cl)NC(C)(C)C.Cl Ambient Ambient 50 mg/ml MeOH "Shah TH, Moradimehr A. Bupropion for the treatment of neuropathic pain. Am J Hosp Palliat Care. 2010 Aug;27(5):333-6. PMID: 20185402.

 

Arias HR. Is the inhibition of nicotinic acetylcholine receptors by bupropion involved in its clinical actions? Int J Biochem Cell Biol. 2009 Nov;41(11):2098-108. PMID: 19497387.

 

Li Z, Maglione M, Tu W, et al. Meta-analysis: pharmacologic treatment of obesity. Ann Intern Med. 2005 Apr 5;142(7):532-46. PMID: 15809465.

 

Miller DK, Sumithran SP, Dwoskin LP. Bupropion inhibits nicotine-evoked [(3)H]overflow from rat striatal slices preloaded with [(3)H]dopamine and from rat hippocampal slices preloaded with [(3)H]norepinephrine. J Pharmacol Exp Ther. 2002 Sep;302(3):1113-22. PMID: 12183670.

 

Dong J, Blier P. Modification of norepinephrine and serotonin, but not dopamine, neuron firing by sustained bupropion treatment. Psychopharmacology (Berl). 2001 Apr;155(1):52-7. PMID: 11374336.

 

Cantwell DP. ADHD through the life span: the role of bupropion in treatment. J Clin Psychiatry. 1998;59 Suppl 4:92-4. PMID: 9554326.

" Xn Not dangerous goods.

LKT B8363 Bupropion Hydrochloride 1 g 611.5 α3β2, α3β4, α4β2 nAChR antagonist, indirect DA and NE reuptake inhibitor. Wellbutrin 31677-93-7 ≥98% 276.2 C13H18ClNO HCl CC(C(=O)C1=CC(=CC=C1)Cl)NC(C)(C)C.Cl Ambient Ambient 50 mg/ml MeOH "Shah TH, Moradimehr A. Bupropion for the treatment of neuropathic pain. Am J Hosp Palliat Care. 2010 Aug;27(5):333-6. PMID: 20185402.

 

Arias HR. Is the inhibition of nicotinic acetylcholine receptors by bupropion involved in its clinical actions? Int J Biochem Cell Biol. 2009 Nov;41(11):2098-108. PMID: 19497387.

 

Li Z, Maglione M, Tu W, et al. Meta-analysis: pharmacologic treatment of obesity. Ann Intern Med. 2005 Apr 5;142(7):532-46. PMID: 15809465.

 

Miller DK, Sumithran SP, Dwoskin LP. Bupropion inhibits nicotine-evoked [(3)H]overflow from rat striatal slices preloaded with [(3)H]dopamine and from rat hippocampal slices preloaded with [(3)H]norepinephrine. J Pharmacol Exp Ther. 2002 Sep;302(3):1113-22. PMID: 12183670.

 

Dong J, Blier P. Modification of norepinephrine and serotonin, but not dopamine, neuron firing by sustained bupropion treatment. Psychopharmacology (Berl). 2001 Apr;155(1):52-7. PMID: 11374336.

 

Cantwell DP. ADHD through the life span: the role of bupropion in treatment. J Clin Psychiatry. 1998;59 Suppl 4:92-4. PMID: 9554326.

" Xn Not dangerous goods.

LKT C0025 Cafestol Eicosanate 25 mg 205.7 Diterpene found in brewed, unfiltered coffee; FXR and PXR agonist, ERK2 and MEK1 inhibitor. ≥98% 610.95 C40H66O4 Ambient -20°C "Wang S, Yoon YC, Sung MJ, et al. Antiangiogenic properties of cafestol, a coffee diterpene, in human umbilical vein endothelial cells. Biochem Biophys Res Commun. 2012 May 11;421(3):567-71. PMID: 22525673.

 

Choi MJ, Park EJ, Oh JH, et al. Cafestol, a coffee-specific diterpene, induces apoptosis in renal carcinoma Caki cells through down-regulation of anti-apoptotic proteins and Akt phosphorylation. Chem Biol Interact. 2011 Apr 25;190(2-3):102-8. PMID: 21334318.

 

Trinh K, Andrews L, Krause J, et al. Decaffeinated coffee and nicotine-free tobacco provide neuroprotection in Drosophila models of Parkinson's disease through an NRF2-dependent mechanism. J Neurosci. 2010 Apr 21;30(16):5525-32. PMID: 20410106.

 

Shen T, Lee J, Lee E, et al. Cafestol, a coffee-specific diterpene, is a novel extracellular signal-regulated kinase inhibitor with AP-1-targeted inhibition of prostaglandin E2 production in lipopolysaccharide-activated macrophages. Biol Pharm Bull. 2010;33(1):128-32. PMID: 20045950.

 

Ricketts ML, Boekschoten MV, Kreeft AJ, et al. The cholesterol-raising factor from coffee beans, cafestol, as an agonist ligand for the farnesoid and pregnane X receptors. Mol Endocrinol. 2007 Jul;21(7):1603-16. PMID: 17456796.

 

Cavin C, Holzhäuser D, Constable A, et al. The coffee-specific diterpenes cafestol and kahweol protect against aflatoxin B1-induced genotoxicity through a dual mechanism. Carcinogenesis. 1998 Aug;19(8):1369-75. PMID: 9744531.

" Not dangerous goods.

LKT C0025 Cafestol Eicosanate 50 mg 359.9 Diterpene found in brewed, unfiltered coffee; FXR and PXR agonist, ERK2 and MEK1 inhibitor. ≥98% 610.95 C40H66O4 Ambient -20°C "Wang S, Yoon YC, Sung MJ, et al. Antiangiogenic properties of cafestol, a coffee diterpene, in human umbilical vein endothelial cells. Biochem Biophys Res Commun. 2012 May 11;421(3):567-71. PMID: 22525673.

 

Choi MJ, Park EJ, Oh JH, et al. Cafestol, a coffee-specific diterpene, induces apoptosis in renal carcinoma Caki cells through down-regulation of anti-apoptotic proteins and Akt phosphorylation. Chem Biol Interact. 2011 Apr 25;190(2-3):102-8. PMID: 21334318.

 

Trinh K, Andrews L, Krause J, et al. Decaffeinated coffee and nicotine-free tobacco provide neuroprotection in Drosophila models of Parkinson's disease through an NRF2-dependent mechanism. J Neurosci. 2010 Apr 21;30(16):5525-32. PMID: 20410106.

 

Shen T, Lee J, Lee E, et al. Cafestol, a coffee-specific diterpene, is a novel extracellular signal-regulated kinase inhibitor with AP-1-targeted inhibition of prostaglandin E2 production in lipopolysaccharide-activated macrophages. Biol Pharm Bull. 2010;33(1):128-32. PMID: 20045950.

 

Ricketts ML, Boekschoten MV, Kreeft AJ, et al. The cholesterol-raising factor from coffee beans, cafestol, as an agonist ligand for the farnesoid and pregnane X receptors. Mol Endocrinol. 2007 Jul;21(7):1603-16. PMID: 17456796.

 

Cavin C, Holzhäuser D, Constable A, et al. The coffee-specific diterpenes cafestol and kahweol protect against aflatoxin B1-induced genotoxicity through a dual mechanism. Carcinogenesis. 1998 Aug;19(8):1369-75. PMID: 9744531.

" Not dangerous goods.

LKT C0025 Cafestol Eicosanate 100 mg 593.7 Diterpene found in brewed, unfiltered coffee; FXR and PXR agonist, ERK2 and MEK1 inhibitor. ≥98% 610.95 C40H66O4 Ambient -20°C "Wang S, Yoon YC, Sung MJ, et al. Antiangiogenic properties of cafestol, a coffee diterpene, in human umbilical vein endothelial cells. Biochem Biophys Res Commun. 2012 May 11;421(3):567-71. PMID: 22525673.

 

Choi MJ, Park EJ, Oh JH, et al. Cafestol, a coffee-specific diterpene, induces apoptosis in renal carcinoma Caki cells through down-regulation of anti-apoptotic proteins and Akt phosphorylation. Chem Biol Interact. 2011 Apr 25;190(2-3):102-8. PMID: 21334318.

 

Trinh K, Andrews L, Krause J, et al. Decaffeinated coffee and nicotine-free tobacco provide neuroprotection in Drosophila models of Parkinson's disease through an NRF2-dependent mechanism. J Neurosci. 2010 Apr 21;30(16):5525-32. PMID: 20410106.

 

Shen T, Lee J, Lee E, et al. Cafestol, a coffee-specific diterpene, is a novel extracellular signal-regulated kinase inhibitor with AP-1-targeted inhibition of prostaglandin E2 production in lipopolysaccharide-activated macrophages. Biol Pharm Bull. 2010;33(1):128-32. PMID: 20045950.

 

Ricketts ML, Boekschoten MV, Kreeft AJ, et al. The cholesterol-raising factor from coffee beans, cafestol, as an agonist ligand for the farnesoid and pregnane X receptors. Mol Endocrinol. 2007 Jul;21(7):1603-16. PMID: 17456796.

 

Cavin C, Holzhäuser D, Constable A, et al. The coffee-specific diterpenes cafestol and kahweol protect against aflatoxin B1-induced genotoxicity through a dual mechanism. Carcinogenesis. 1998 Aug;19(8):1369-75. PMID: 9744531.

" Not dangerous goods.

LKT C0027 Cafestol Linoleate 25 mg 199.6 Diterpene found in brewed, unfiltered coffee; FXR and PXR agonist, ERK2 and MEK1 inhibitor. ≥98% 578.87 C38H58O4 Ambient -20°C "Wang S, Yoon YC, Sung MJ, et al. Antiangiogenic properties of cafestol, a coffee diterpene, in human umbilical vein endothelial cells. Biochem Biophys Res Commun. 2012 May 11;421(3):567-71. PMID: 22525673.

 

Choi MJ, Park EJ, Oh JH, et al. Cafestol, a coffee-specific diterpene, induces apoptosis in renal carcinoma Caki cells through down-regulation of anti-apoptotic proteins and Akt phosphorylation. Chem Biol Interact. 2011 Apr 25;190(2-3):102-8. PMID: 21334318.

 

Trinh K, Andrews L, Krause J, et al. Decaffeinated coffee and nicotine-free tobacco provide neuroprotection in Drosophila models of Parkinson's disease through an NRF2-dependent mechanism. J Neurosci. 2010 Apr 21;30(16):5525-32. PMID: 20410106.

 

Shen T, Lee J, Lee E, et al. Cafestol, a coffee-specific diterpene, is a novel extracellular signal-regulated kinase inhibitor with AP-1-targeted inhibition of prostaglandin E2 production in lipopolysaccharide-activated macrophages. Biol Pharm Bull. 2010;33(1):128-32. PMID: 20045950.

 

Ricketts ML, Boekschoten MV, Kreeft AJ, et al. The cholesterol-raising factor from coffee beans, cafestol, as an agonist ligand for the farnesoid and pregnane X receptors. Mol Endocrinol. 2007 Jul;21(7):1603-16. PMID: 17456796.

 

Cavin C, Holzhäuser D, Constable A, et al. The coffee-specific diterpenes cafestol and kahweol protect against aflatoxin B1-induced genotoxicity through a dual mechanism. Carcinogenesis. 1998 Aug;19(8):1369-75. PMID: 9744531.

" Not dangerous goods.

LKT C0027 Cafestol Linoleate 50 mg 347.9 Diterpene found in brewed, unfiltered coffee; FXR and PXR agonist, ERK2 and MEK1 inhibitor. ≥98% 578.87 C38H58O4 Ambient -20°C "Wang S, Yoon YC, Sung MJ, et al. Antiangiogenic properties of cafestol, a coffee diterpene, in human umbilical vein endothelial cells. Biochem Biophys Res Commun. 2012 May 11;421(3):567-71. PMID: 22525673.

 

Choi MJ, Park EJ, Oh JH, et al. Cafestol, a coffee-specific diterpene, induces apoptosis in renal carcinoma Caki cells through down-regulation of anti-apoptotic proteins and Akt phosphorylation. Chem Biol Interact. 2011 Apr 25;190(2-3):102-8. PMID: 21334318.

 

Trinh K, Andrews L, Krause J, et al. Decaffeinated coffee and nicotine-free tobacco provide neuroprotection in Drosophila models of Parkinson's disease through an NRF2-dependent mechanism. J Neurosci. 2010 Apr 21;30(16):5525-32. PMID: 20410106.

 

Shen T, Lee J, Lee E, et al. Cafestol, a coffee-specific diterpene, is a novel extracellular signal-regulated kinase inhibitor with AP-1-targeted inhibition of prostaglandin E2 production in lipopolysaccharide-activated macrophages. Biol Pharm Bull. 2010;33(1):128-32. PMID: 20045950.

 

Ricketts ML, Boekschoten MV, Kreeft AJ, et al. The cholesterol-raising factor from coffee beans, cafestol, as an agonist ligand for the farnesoid and pregnane X receptors. Mol Endocrinol. 2007 Jul;21(7):1603-16. PMID: 17456796.

 

Cavin C, Holzhäuser D, Constable A, et al. The coffee-specific diterpenes cafestol and kahweol protect against aflatoxin B1-induced genotoxicity through a dual mechanism. Carcinogenesis. 1998 Aug;19(8):1369-75. PMID: 9744531.

" Not dangerous goods.

LKT C0027 Cafestol Linoleate 100 mg 554.8 Diterpene found in brewed, unfiltered coffee; FXR and PXR agonist, ERK2 and MEK1 inhibitor. ≥98% 578.87 C38H58O4 Ambient -20°C "Wang S, Yoon YC, Sung MJ, et al. Antiangiogenic properties of cafestol, a coffee diterpene, in human umbilical vein endothelial cells. Biochem Biophys Res Commun. 2012 May 11;421(3):567-71. PMID: 22525673.

 

Choi MJ, Park EJ, Oh JH, et al. Cafestol, a coffee-specific diterpene, induces apoptosis in renal carcinoma Caki cells through down-regulation of anti-apoptotic proteins and Akt phosphorylation. Chem Biol Interact. 2011 Apr 25;190(2-3):102-8. PMID: 21334318.

 

Trinh K, Andrews L, Krause J, et al. Decaffeinated coffee and nicotine-free tobacco provide neuroprotection in Drosophila models of Parkinson's disease through an NRF2-dependent mechanism. J Neurosci. 2010 Apr 21;30(16):5525-32. PMID: 20410106.

 

Shen T, Lee J, Lee E, et al. Cafestol, a coffee-specific diterpene, is a novel extracellular signal-regulated kinase inhibitor with AP-1-targeted inhibition of prostaglandin E2 production in lipopolysaccharide-activated macrophages. Biol Pharm Bull. 2010;33(1):128-32. PMID: 20045950.

 

Ricketts ML, Boekschoten MV, Kreeft AJ, et al. The cholesterol-raising factor from coffee beans, cafestol, as an agonist ligand for the farnesoid and pregnane X receptors. Mol Endocrinol. 2007 Jul;21(7):1603-16. PMID: 17456796.

 

Cavin C, Holzhäuser D, Constable A, et al. The coffee-specific diterpenes cafestol and kahweol protect against aflatoxin B1-induced genotoxicity through a dual mechanism. Carcinogenesis. 1998 Aug;19(8):1369-75. PMID: 9744531.

" Not dangerous goods.

LKT C0029 Cafestol Oleate 25 mg 225 Diterpene found in brewed, unfiltered coffee; FXR and PXR agonist, ERK2 and MEK1 inhibitor. ≥98% 580.88 C38H60O4 Ambient -20°C "Wang S, Yoon YC, Sung MJ, et al. Antiangiogenic properties of cafestol, a coffee diterpene, in human umbilical vein endothelial cells. Biochem Biophys Res Commun. 2012 May 11;421(3):567-71. PMID: 22525673.

 

Choi MJ, Park EJ, Oh JH, et al. Cafestol, a coffee-specific diterpene, induces apoptosis in renal carcinoma Caki cells through down-regulation of anti-apoptotic proteins and Akt phosphorylation. Chem Biol Interact. 2011 Apr 25;190(2-3):102-8. PMID: 21334318.

 

Trinh K, Andrews L, Krause J, et al. Decaffeinated coffee and nicotine-free tobacco provide neuroprotection in Drosophila models of Parkinson's disease through an NRF2-dependent mechanism. J Neurosci. 2010 Apr 21;30(16):5525-32. PMID: 20410106.

 

Shen T, Lee J, Lee E, et al. Cafestol, a coffee-specific diterpene, is a novel extracellular signal-regulated kinase inhibitor with AP-1-targeted inhibition of prostaglandin E2 production in lipopolysaccharide-activated macrophages. Biol Pharm Bull. 2010;33(1):128-32. PMID: 20045950.

 

Ricketts ML, Boekschoten MV, Kreeft AJ, et al. The cholesterol-raising factor from coffee beans, cafestol, as an agonist ligand for the farnesoid and pregnane X receptors. Mol Endocrinol. 2007 Jul;21(7):1603-16. PMID: 17456796.

 

Cavin C, Holzhäuser D, Constable A, et al. The coffee-specific diterpenes cafestol and kahweol protect against aflatoxin B1-induced genotoxicity through a dual mechanism. Carcinogenesis. 1998 Aug;19(8):1369-75. PMID: 9744531.

" Not dangerous goods.

LKT C0029 Cafestol Oleate 50 mg 404.8 Diterpene found in brewed, unfiltered coffee; FXR and PXR agonist, ERK2 and MEK1 inhibitor. ≥98% 580.88 C38H60O4 Ambient -20°C "Wang S, Yoon YC, Sung MJ, et al. Antiangiogenic properties of cafestol, a coffee diterpene, in human umbilical vein endothelial cells. Biochem Biophys Res Commun. 2012 May 11;421(3):567-71. PMID: 22525673.

 

Choi MJ, Park EJ, Oh JH, et al. Cafestol, a coffee-specific diterpene, induces apoptosis in renal carcinoma Caki cells through down-regulation of anti-apoptotic proteins and Akt phosphorylation. Chem Biol Interact. 2011 Apr 25;190(2-3):102-8. PMID: 21334318.

 

Trinh K, Andrews L, Krause J, et al. Decaffeinated coffee and nicotine-free tobacco provide neuroprotection in Drosophila models of Parkinson's disease through an NRF2-dependent mechanism. J Neurosci. 2010 Apr 21;30(16):5525-32. PMID: 20410106.

 

Shen T, Lee J, Lee E, et al. Cafestol, a coffee-specific diterpene, is a novel extracellular signal-regulated kinase inhibitor with AP-1-targeted inhibition of prostaglandin E2 production in lipopolysaccharide-activated macrophages. Biol Pharm Bull. 2010;33(1):128-32. PMID: 20045950.

 

Ricketts ML, Boekschoten MV, Kreeft AJ, et al. The cholesterol-raising factor from coffee beans, cafestol, as an agonist ligand for the farnesoid and pregnane X receptors. Mol Endocrinol. 2007 Jul;21(7):1603-16. PMID: 17456796.

 

Cavin C, Holzhäuser D, Constable A, et al. The coffee-specific diterpenes cafestol and kahweol protect against aflatoxin B1-induced genotoxicity through a dual mechanism. Carcinogenesis. 1998 Aug;19(8):1369-75. PMID: 9744531.

" Not dangerous goods.

LKT C0029 Cafestol Oleate 100 mg 614.7 Diterpene found in brewed, unfiltered coffee; FXR and PXR agonist, ERK2 and MEK1 inhibitor. ≥98% 580.88 C38H60O4 Ambient -20°C "Wang S, Yoon YC, Sung MJ, et al. Antiangiogenic properties of cafestol, a coffee diterpene, in human umbilical vein endothelial cells. Biochem Biophys Res Commun. 2012 May 11;421(3):567-71. PMID: 22525673.

 

Choi MJ, Park EJ, Oh JH, et al. Cafestol, a coffee-specific diterpene, induces apoptosis in renal carcinoma Caki cells through down-regulation of anti-apoptotic proteins and Akt phosphorylation. Chem Biol Interact. 2011 Apr 25;190(2-3):102-8. PMID: 21334318.

 

Trinh K, Andrews L, Krause J, et al. Decaffeinated coffee and nicotine-free tobacco provide neuroprotection in Drosophila models of Parkinson's disease through an NRF2-dependent mechanism. J Neurosci. 2010 Apr 21;30(16):5525-32. PMID: 20410106.

 

Shen T, Lee J, Lee E, et al. Cafestol, a coffee-specific diterpene, is a novel extracellular signal-regulated kinase inhibitor with AP-1-targeted inhibition of prostaglandin E2 production in lipopolysaccharide-activated macrophages. Biol Pharm Bull. 2010;33(1):128-32. PMID: 20045950.

 

Ricketts ML, Boekschoten MV, Kreeft AJ, et al. The cholesterol-raising factor from coffee beans, cafestol, as an agonist ligand for the farnesoid and pregnane X receptors. Mol Endocrinol. 2007 Jul;21(7):1603-16. PMID: 17456796.

 

Cavin C, Holzhäuser D, Constable A, et al. The coffee-specific diterpenes cafestol and kahweol protect against aflatoxin B1-induced genotoxicity through a dual mechanism. Carcinogenesis. 1998 Aug;19(8):1369-75. PMID: 9744531.

" Not dangerous goods.

LKT C0033 Cafestol Stearate 25 mg 192.4 Diterpene found in brewed, unfiltered coffee; FXR and PXR agonist, ERK2 and MEK1 inhibitor. ≥98% 582.9 C38H62O4 Ambient -20°C "Wang S, Yoon YC, Sung MJ, et al. Antiangiogenic properties of cafestol, a coffee diterpene, in human umbilical vein endothelial cells. Biochem Biophys Res Commun. 2012 May 11;421(3):567-71. PMID: 22525673.

 

Choi MJ, Park EJ, Oh JH, et al. Cafestol, a coffee-specific diterpene, induces apoptosis in renal carcinoma Caki cells through down-regulation of anti-apoptotic proteins and Akt phosphorylation. Chem Biol Interact. 2011 Apr 25;190(2-3):102-8. PMID: 21334318.

 

Trinh K, Andrews L, Krause J, et al. Decaffeinated coffee and nicotine-free tobacco provide neuroprotection in Drosophila models of Parkinson's disease through an NRF2-dependent mechanism. J Neurosci. 2010 Apr 21;30(16):5525-32. PMID: 20410106.

 

Shen T, Lee J, Lee E, et al. Cafestol, a coffee-specific diterpene, is a novel extracellular signal-regulated kinase inhibitor with AP-1-targeted inhibition of prostaglandin E2 production in lipopolysaccharide-activated macrophages. Biol Pharm Bull. 2010;33(1):128-32. PMID: 20045950.

 

Ricketts ML, Boekschoten MV, Kreeft AJ, et al. The cholesterol-raising factor from coffee beans, cafestol, as an agonist ligand for the farnesoid and pregnane X receptors. Mol Endocrinol. 2007 Jul;21(7):1603-16. PMID: 17456796.

 

Cavin C, Holzhäuser D, Constable A, et al. The coffee-specific diterpenes cafestol and kahweol protect against aflatoxin B1-induced genotoxicity through a dual mechanism. Carcinogenesis. 1998 Aug;19(8):1369-75. PMID: 9744531.

" Not dangerous goods.

LKT C0033 Cafestol Stearate 50 mg 340.2 Diterpene found in brewed, unfiltered coffee; FXR and PXR agonist, ERK2 and MEK1 inhibitor. ≥98% 582.9 C38H62O4 Ambient -20°C "Wang S, Yoon YC, Sung MJ, et al. Antiangiogenic properties of cafestol, a coffee diterpene, in human umbilical vein endothelial cells. Biochem Biophys Res Commun. 2012 May 11;421(3):567-71. PMID: 22525673.

 

Choi MJ, Park EJ, Oh JH, et al. Cafestol, a coffee-specific diterpene, induces apoptosis in renal carcinoma Caki cells through down-regulation of anti-apoptotic proteins and Akt phosphorylation. Chem Biol Interact. 2011 Apr 25;190(2-3):102-8. PMID: 21334318.

 

Trinh K, Andrews L, Krause J, et al. Decaffeinated coffee and nicotine-free tobacco provide neuroprotection in Drosophila models of Parkinson's disease through an NRF2-dependent mechanism. J Neurosci. 2010 Apr 21;30(16):5525-32. PMID: 20410106.

 

Shen T, Lee J, Lee E, et al. Cafestol, a coffee-specific diterpene, is a novel extracellular signal-regulated kinase inhibitor with AP-1-targeted inhibition of prostaglandin E2 production in lipopolysaccharide-activated macrophages. Biol Pharm Bull. 2010;33(1):128-32. PMID: 20045950.

 

Ricketts ML, Boekschoten MV, Kreeft AJ, et al. The cholesterol-raising factor from coffee beans, cafestol, as an agonist ligand for the farnesoid and pregnane X receptors. Mol Endocrinol. 2007 Jul;21(7):1603-16. PMID: 17456796.

 

Cavin C, Holzhäuser D, Constable A, et al. The coffee-specific diterpenes cafestol and kahweol protect against aflatoxin B1-induced genotoxicity through a dual mechanism. Carcinogenesis. 1998 Aug;19(8):1369-75. PMID: 9744531.

" Not dangerous goods.

LKT C0033 Cafestol Stearate 100 mg 542.7 Diterpene found in brewed, unfiltered coffee; FXR and PXR agonist, ERK2 and MEK1 inhibitor. ≥98% 582.9 C38H62O4 Ambient -20°C "Wang S, Yoon YC, Sung MJ, et al. Antiangiogenic properties of cafestol, a coffee diterpene, in human umbilical vein endothelial cells. Biochem Biophys Res Commun. 2012 May 11;421(3):567-71. PMID: 22525673.

 

Choi MJ, Park EJ, Oh JH, et al. Cafestol, a coffee-specific diterpene, induces apoptosis in renal carcinoma Caki cells through down-regulation of anti-apoptotic proteins and Akt phosphorylation. Chem Biol Interact. 2011 Apr 25;190(2-3):102-8. PMID: 21334318.

 

Trinh K, Andrews L, Krause J, et al. Decaffeinated coffee and nicotine-free tobacco provide neuroprotection in Drosophila models of Parkinson's disease through an NRF2-dependent mechanism. J Neurosci. 2010 Apr 21;30(16):5525-32. PMID: 20410106.

 

Shen T, Lee J, Lee E, et al. Cafestol, a coffee-specific diterpene, is a novel extracellular signal-regulated kinase inhibitor with AP-1-targeted inhibition of prostaglandin E2 production in lipopolysaccharide-activated macrophages. Biol Pharm Bull. 2010;33(1):128-32. PMID: 20045950.

 

Ricketts ML, Boekschoten MV, Kreeft AJ, et al. The cholesterol-raising factor from coffee beans, cafestol, as an agonist ligand for the farnesoid and pregnane X receptors. Mol Endocrinol. 2007 Jul;21(7):1603-16. PMID: 17456796.

 

Cavin C, Holzhäuser D, Constable A, et al. The coffee-specific diterpenes cafestol and kahweol protect against aflatoxin B1-induced genotoxicity through a dual mechanism. Carcinogenesis. 1998 Aug;19(8):1369-75. PMID: 9744531.

" Not dangerous goods.

LKT Z5744 Zoledronic Acid Hydrate 10 mg 61.1 Bisphosphonate; FPPS inhibitor. [1-Hydroxy-2-(1H-imidazol-1-yl)ethylidene]- bisphosphonic acid Zoledronate; Zometa 165800-06-6 ≥98% 290.1 C5H10N2O7P2 H2O C1=CN(C=N1)CC(O)(P(=O)(O)O)P(=O)(O)O Ambient Ambient Soluble in 0.1 N sodium hydroxide. "Yang T, Zheng XF, Li M, et al. Stimulation of osteogenic differentiation in stromal cells of giant cell tumour of bone by zoledronic acid. Asian Pac J Cancer Prev. 2013;14(9):5379-83. PMID: 24175830.

 

Schech AJ, Kazi AA, Gilani RA, et al. Zoledronic acid reverses the epithelial-mesenchymal transition and inhibits self-renewal of breast cancer cells through inactivation of NF-κB. Mol Cancer Ther. 2013 Jul;12(7):1356-66. PMID: 23619300.

 

Idrees AS, Sugie T, Inoue C, et al. Comparison of γδ T cell responses and farnesyl diphosphate synthase inhibition in tumor cells pretreated with zoledronic acid. Cancer Sci. 2013 May;104(5):536-42. PMID: 23387443.

 

Ibrahim T, Mercatali L, Sacanna E, et al. Inhibition of breast cancer cell proliferation in repeated and non-repeated treatment with zoledronic acid. Cancer Cell Int. 2012 Nov 22;12(1):48. PMID: 23173568.

 

Soltau J, Zirrgiebel U, Esser N, et al. Antitumoral and antiangiogenic efficacy of bisphosphonates in vitro and in a murine RENCA model. Anticancer Res. 2008 Mar-Apr;28(2A):933-41. PMID: 18507039.

 

Kavanagh KL, Guo K, Dunford JE, et al The molecular mechanism of nitrogen-containing bisphosphonates as antiosteoporosis drugs. Proc Natl Acad Sci U S A. 2006 May 16;103(20):7829-34. PMID: 16684881.

" Xi, Xn Not dangerous goods.

LKT Z5744 Zoledronic Acid Hydrate 25 mg 95.1 Bisphosphonate; FPPS inhibitor. [1-Hydroxy-2-(1H-imidazol-1-yl)ethylidene]- bisphosphonic acid Zoledronate; Zometa 165800-06-6 ≥98% 290.1 C5H10N2O7P2 H2O C1=CN(C=N1)CC(O)(P(=O)(O)O)P(=O)(O)O Ambient Ambient Soluble in 0.1 N sodium hydroxide. "Yang T, Zheng XF, Li M, et al. Stimulation of osteogenic differentiation in stromal cells of giant cell tumour of bone by zoledronic acid. Asian Pac J Cancer Prev. 2013;14(9):5379-83. PMID: 24175830.

 

Schech AJ, Kazi AA, Gilani RA, et al. Zoledronic acid reverses the epithelial-mesenchymal transition and inhibits self-renewal of breast cancer cells through inactivation of NF-κB. Mol Cancer Ther. 2013 Jul;12(7):1356-66. PMID: 23619300.

 

Idrees AS, Sugie T, Inoue C, et al. Comparison of γδ T cell responses and farnesyl diphosphate synthase inhibition in tumor cells pretreated with zoledronic acid. Cancer Sci. 2013 May;104(5):536-42. PMID: 23387443.

 

Ibrahim T, Mercatali L, Sacanna E, et al. Inhibition of breast cancer cell proliferation in repeated and non-repeated treatment with zoledronic acid. Cancer Cell Int. 2012 Nov 22;12(1):48. PMID: 23173568.

 

Soltau J, Zirrgiebel U, Esser N, et al. Antitumoral and antiangiogenic efficacy of bisphosphonates in vitro and in a murine RENCA model. Anticancer Res. 2008 Mar-Apr;28(2A):933-41. PMID: 18507039.

 

Kavanagh KL, Guo K, Dunford JE, et al The molecular mechanism of nitrogen-containing bisphosphonates as antiosteoporosis drugs. Proc Natl Acad Sci U S A. 2006 May 16;103(20):7829-34. PMID: 16684881.

" Xi, Xn Not dangerous goods.

LKT Z5744 Zoledronic Acid Hydrate 100 mg 285.4 Bisphosphonate; FPPS inhibitor. [1-Hydroxy-2-(1H-imidazol-1-yl)ethylidene]- bisphosphonic acid Zoledronate; Zometa 165800-06-6 ≥98% 290.1 C5H10N2O7P2 H2O C1=CN(C=N1)CC(O)(P(=O)(O)O)P(=O)(O)O Ambient Ambient Soluble in 0.1 N sodium hydroxide. "Yang T, Zheng XF, Li M, et al. Stimulation of osteogenic differentiation in stromal cells of giant cell tumour of bone by zoledronic acid. Asian Pac J Cancer Prev. 2013;14(9):5379-83. PMID: 24175830.

 

Schech AJ, Kazi AA, Gilani RA, et al. Zoledronic acid reverses the epithelial-mesenchymal transition and inhibits self-renewal of breast cancer cells through inactivation of NF-κB. Mol Cancer Ther. 2013 Jul;12(7):1356-66. PMID: 23619300.

 

Idrees AS, Sugie T, Inoue C, et al. Comparison of γδ T cell responses and farnesyl diphosphate synthase inhibition in tumor cells pretreated with zoledronic acid. Cancer Sci. 2013 May;104(5):536-42. PMID: 23387443.

 

Ibrahim T, Mercatali L, Sacanna E, et al. Inhibition of breast cancer cell proliferation in repeated and non-repeated treatment with zoledronic acid. Cancer Cell Int. 2012 Nov 22;12(1):48. PMID: 23173568.

 

Soltau J, Zirrgiebel U, Esser N, et al. Antitumoral and antiangiogenic efficacy of bisphosphonates in vitro and in a murine RENCA model. Anticancer Res. 2008 Mar-Apr;28(2A):933-41. PMID: 18507039.

 

Kavanagh KL, Guo K, Dunford JE, et al The molecular mechanism of nitrogen-containing bisphosphonates as antiosteoporosis drugs. Proc Natl Acad Sci U S A. 2006 May 16;103(20):7829-34. PMID: 16684881.

" Xi, Xn Not dangerous goods.

LKT C0140 Calcitonin, eel 1 mg 180 Endogenous neuropeptide hormone, lowers extracellular Ca2+ levels. ≥95% 3414.94 C146H241N43O47S2 Ambient -20°C soluble in water "Tsagaraki I, Phenekos C, Tsilibary E, et al. Calcitonin-induced NF-κB activation up-regulates fibronectin expression in MG63 osteosarcoma cells. Anticancer Res. 2013 Nov;33(11):4901-6. PMID: 24222127.

 

Armagan O, Serin DK, Calisir C, et al. Inhalation therapy of calcitonin relieves osteoarthritis of the knee. J Korean Med Sci. 2012 Nov;27(11):1405-10. PMID: 23166425.

 

Kuo YJ, Tsuang FY, Sun JS, et al. Calcitonin inhibits SDCP-induced osteoclast apoptosis and increases its efficacy in a rat model of osteoporosis. PLoS One. 2012;7(7):e40272. PMID: 22792258.

" Not dangerous goods.

LKT C0140 Calcitonin, eel 2 mg 306.1 Endogenous neuropeptide hormone, lowers extracellular Ca2+ levels. ≥95% 3414.94 C146H241N43O47S2 Ambient -20°C soluble in water "Tsagaraki I, Phenekos C, Tsilibary E, et al. Calcitonin-induced NF-κB activation up-regulates fibronectin expression in MG63 osteosarcoma cells. Anticancer Res. 2013 Nov;33(11):4901-6. PMID: 24222127.

 

Armagan O, Serin DK, Calisir C, et al. Inhalation therapy of calcitonin relieves osteoarthritis of the knee. J Korean Med Sci. 2012 Nov;27(11):1405-10. PMID: 23166425.

 

Kuo YJ, Tsuang FY, Sun JS, et al. Calcitonin inhibits SDCP-induced osteoclast apoptosis and increases its efficacy in a rat model of osteoporosis. PLoS One. 2012;7(7):e40272. PMID: 22792258.

" Not dangerous goods.

LKT C0140 Calcitonin, eel 5 mg 540 Endogenous neuropeptide hormone, lowers extracellular Ca2+ levels. ≥95% 3414.94 C146H241N43O47S2 Ambient -20°C soluble in water "Tsagaraki I, Phenekos C, Tsilibary E, et al. Calcitonin-induced NF-κB activation up-regulates fibronectin expression in MG63 osteosarcoma cells. Anticancer Res. 2013 Nov;33(11):4901-6. PMID: 24222127.

 

Armagan O, Serin DK, Calisir C, et al. Inhalation therapy of calcitonin relieves osteoarthritis of the knee. J Korean Med Sci. 2012 Nov;27(11):1405-10. PMID: 23166425.

 

Kuo YJ, Tsuang FY, Sun JS, et al. Calcitonin inhibits SDCP-induced osteoclast apoptosis and increases its efficacy in a rat model of osteoporosis. PLoS One. 2012;7(7):e40272. PMID: 22792258.

" Not dangerous goods.

LKT Z5653 Zonisamide 10 mg 67.9 Sulfonamide; carbonic anhydrase inhibitor, voltage-gated Na+ and T-type Ca2+ channel blocker. 1,2-Benzisoxazole-3-methanesulfonamide AD-810; CI-912; Excegran 68291-97-4 ≥96% 212.23 C8H8N2O3S C1=CC=C2C(=C1)C(=NO2)CS(=O)(=O)N Ambient Ambient Sparingly soluble in water.  Soluble in methanol, ethanol, DMSO. "Arawaka S, Fukushima S, Sato H, et al. Zonisamide attenuates α-synuclein neurotoxicity by an aggregation-independent mechanism in a rat model of familial Parkinson's disease. PLoS One. 2014 Feb 20;9(2):e89076. PMID: 24586512.

 

Aggarwal M, Kondeti B, McKenna R. Anticonvulsant/antiepileptic carbonic anhydrase inhibitors: a patent review. Expert Opin Ther Pat. 2013;23(6):717-24. PMID: 23514045.

 

Holder JL Jr, Wilfong AA. Zonisamide in the treatment of epilepsy. Expert Opin Pharmacother. 2011 Nov;12(16):2573-81. PMID: 21967409.

 

Baulac M, Leppik IE. Efficacy and safety of adjunctive zonisamide therapy for refractory partial seizures. Epilepsy Res. 2007 Jul;75(2-3):75-83. PMID: 17553670.

" Not dangerous goods.

LKT Z5653 Zonisamide 25 mg 149.5 Sulfonamide; carbonic anhydrase inhibitor, voltage-gated Na+ and T-type Ca2+ channel blocker. 1,2-Benzisoxazole-3-methanesulfonamide AD-810; CI-912; Excegran 68291-97-4 ≥96% 212.23 C8H8N2O3S C1=CC=C2C(=C1)C(=NO2)CS(=O)(=O)N Ambient Ambient Sparingly soluble in water.  Soluble in methanol, ethanol, DMSO. "Arawaka S, Fukushima S, Sato H, et al. Zonisamide attenuates α-synuclein neurotoxicity by an aggregation-independent mechanism in a rat model of familial Parkinson's disease. PLoS One. 2014 Feb 20;9(2):e89076. PMID: 24586512.

 

Aggarwal M, Kondeti B, McKenna R. Anticonvulsant/antiepileptic carbonic anhydrase inhibitors: a patent review. Expert Opin Ther Pat. 2013;23(6):717-24. PMID: 23514045.

 

Holder JL Jr, Wilfong AA. Zonisamide in the treatment of epilepsy. Expert Opin Pharmacother. 2011 Nov;12(16):2573-81. PMID: 21967409.

 

Baulac M, Leppik IE. Efficacy and safety of adjunctive zonisamide therapy for refractory partial seizures. Epilepsy Res. 2007 Jul;75(2-3):75-83. PMID: 17553670.

" Not dangerous goods.

LKT Z5653 Zonisamide 100 mg 502.8 Sulfonamide; carbonic anhydrase inhibitor, voltage-gated Na+ and T-type Ca2+ channel blocker. 1,2-Benzisoxazole-3-methanesulfonamide AD-810; CI-912; Excegran 68291-97-4 ≥96% 212.23 C8H8N2O3S C1=CC=C2C(=C1)C(=NO2)CS(=O)(=O)N Ambient Ambient Sparingly soluble in water.  Soluble in methanol, ethanol, DMSO. "Arawaka S, Fukushima S, Sato H, et al. Zonisamide attenuates α-synuclein neurotoxicity by an aggregation-independent mechanism in a rat model of familial Parkinson's disease. PLoS One. 2014 Feb 20;9(2):e89076. PMID: 24586512.

 

Aggarwal M, Kondeti B, McKenna R. Anticonvulsant/antiepileptic carbonic anhydrase inhibitors: a patent review. Expert Opin Ther Pat. 2013;23(6):717-24. PMID: 23514045.

 

Holder JL Jr, Wilfong AA. Zonisamide in the treatment of epilepsy. Expert Opin Pharmacother. 2011 Nov;12(16):2573-81. PMID: 21967409.

 

Baulac M, Leppik IE. Efficacy and safety of adjunctive zonisamide therapy for refractory partial seizures. Epilepsy Res. 2007 Jul;75(2-3):75-83. PMID: 17553670.

" Not dangerous goods.

LKT C0146 Calcitonin, chicken 0.5 mg 180 Endogenous neuropeptide hormone, lowers extracellular Ca2+ levels. 9007-12-9 ≥95% 3371.91 C145H240N42O46S2 "CC(C)CC1C(=O)NC(C(=O)NC(C(=O)NC(CSSCC(C(=O)NC(C(=O)NC(C(=O)N1)CC(=O)N)CO)N)C(=O)NC(C(C)C)C(=O)NC(CC(C)C)C(=O)NCC(=O)NC(CCCCN)C(=O)NC(CC(C)C)C(=O)NC(CO)C(=O)NC(CCC(=O)N)C(=O)NC(CCC(=O)O)C(=O)NC(CC(C)C)C(=O)NC(Cc2cnc[nH]2)C(=O)NC(CCCCN)C(=O)NC(CC(C)C)C(=O)NC(CCC(=O)N)C(=O)NC(C(C)O)C(=O)NC(Cc3ccc(cc3)O)C(=O)N4CCCC4C(=O)NC(CCCNC(=N)N)C(=O)NC(C(C)O)C(=O)NC(CC(=O)N)C(=O)NC(C(C)O)C(=O)NCC(=O)NC(CO)C(=O)NCC(=O)NC(C(C)O)C(=O)N5CCCC5C(=O)N)C(C)O)CO

" Ambient -20°C "Tsagaraki I, Phenekos C, Tsilibary E, et al. Calcitonin-induced NF-κB activation up-regulates fibronectin expression in MG63 osteosarcoma cells. Anticancer Res. 2013 Nov;33(11):4901-6. PMID: 24222127.

 

Armagan O, Serin DK, Calisir C, et al. Inhalation therapy of calcitonin relieves osteoarthritis of the knee. J Korean Med Sci. 2012 Nov;27(11):1405-10. PMID: 23166425.

 

Kuo YJ, Tsuang FY, Sun JS, et al. Calcitonin inhibits SDCP-induced osteoclast apoptosis and increases its efficacy in a rat model of osteoporosis. PLoS One. 2012;7(7):e40272. PMID: 22792258.

" Not dangerous goods.

LKT C0146 Calcitonin, chicken 1 mg 306.1 Endogenous neuropeptide hormone, lowers extracellular Ca2+ levels. 9007-12-9 ≥95% 3371.91 C145H240N42O46S2 "CC(C)CC1C(=O)NC(C(=O)NC(C(=O)NC(CSSCC(C(=O)NC(C(=O)NC(C(=O)N1)CC(=O)N)CO)N)C(=O)NC(C(C)C)C(=O)NC(CC(C)C)C(=O)NCC(=O)NC(CCCCN)C(=O)NC(CC(C)C)C(=O)NC(CO)C(=O)NC(CCC(=O)N)C(=O)NC(CCC(=O)O)C(=O)NC(CC(C)C)C(=O)NC(Cc2cnc[nH]2)C(=O)NC(CCCCN)C(=O)NC(CC(C)C)C(=O)NC(CCC(=O)N)C(=O)NC(C(C)O)C(=O)NC(Cc3ccc(cc3)O)C(=O)N4CCCC4C(=O)NC(CCCNC(=N)N)C(=O)NC(C(C)O)C(=O)NC(CC(=O)N)C(=O)NC(C(C)O)C(=O)NCC(=O)NC(CO)C(=O)NCC(=O)NC(C(C)O)C(=O)N5CCCC5C(=O)N)C(C)O)CO

" Ambient -20°C "Tsagaraki I, Phenekos C, Tsilibary E, et al. Calcitonin-induced NF-κB activation up-regulates fibronectin expression in MG63 osteosarcoma cells. Anticancer Res. 2013 Nov;33(11):4901-6. PMID: 24222127.

 

Armagan O, Serin DK, Calisir C, et al. Inhalation therapy of calcitonin relieves osteoarthritis of the knee. J Korean Med Sci. 2012 Nov;27(11):1405-10. PMID: 23166425.

 

Kuo YJ, Tsuang FY, Sun JS, et al. Calcitonin inhibits SDCP-induced osteoclast apoptosis and increases its efficacy in a rat model of osteoporosis. PLoS One. 2012;7(7):e40272. PMID: 22792258.

" Not dangerous goods.

LKT C0146 Calcitonin, chicken 2.5 mg 540 Endogenous neuropeptide hormone, lowers extracellular Ca2+ levels. 9007-12-9 ≥95% 3371.91 C145H240N42O46S2 "CC(C)CC1C(=O)NC(C(=O)NC(C(=O)NC(CSSCC(C(=O)NC(C(=O)NC(C(=O)N1)CC(=O)N)CO)N)C(=O)NC(C(C)C)C(=O)NC(CC(C)C)C(=O)NCC(=O)NC(CCCCN)C(=O)NC(CC(C)C)C(=O)NC(CO)C(=O)NC(CCC(=O)N)C(=O)NC(CCC(=O)O)C(=O)NC(CC(C)C)C(=O)NC(Cc2cnc[nH]2)C(=O)NC(CCCCN)C(=O)NC(CC(C)C)C(=O)NC(CCC(=O)N)C(=O)NC(C(C)O)C(=O)NC(Cc3ccc(cc3)O)C(=O)N4CCCC4C(=O)NC(CCCNC(=N)N)C(=O)NC(C(C)O)C(=O)NC(CC(=O)N)C(=O)NC(C(C)O)C(=O)NCC(=O)NC(CO)C(=O)NCC(=O)NC(C(C)O)C(=O)N5CCCC5C(=O)N)C(C)O)CO

" Ambient -20°C "Tsagaraki I, Phenekos C, Tsilibary E, et al. Calcitonin-induced NF-κB activation up-regulates fibronectin expression in MG63 osteosarcoma cells. Anticancer Res. 2013 Nov;33(11):4901-6. PMID: 24222127.

 

Armagan O, Serin DK, Calisir C, et al. Inhalation therapy of calcitonin relieves osteoarthritis of the knee. J Korean Med Sci. 2012 Nov;27(11):1405-10. PMID: 23166425.

 

Kuo YJ, Tsuang FY, Sun JS, et al. Calcitonin inhibits SDCP-induced osteoclast apoptosis and increases its efficacy in a rat model of osteoporosis. PLoS One. 2012;7(7):e40272. PMID: 22792258.

" Not dangerous goods.

LKT C0148 Calcitonin, human 0.5 mg 162 Endogenous neuropeptide hormone, lowers extracellular Ca2+ levels. H-Cys-Gly-Asn-Leu-Ser-Thr-Cys-Met-Leu-Gly-Thr- Tyr-Thr-Gln-Asp-Phe-Asn-Lys-Phe-His-Thr-Phe-Pro-Gln-Thr-Ala-Ile-Gly-Val-Gly-Ala-Pro-NH2 Calcitonin M, human C carcinoma; hCT; Thyrocalcitonin 21215-62-3 ≥95% 3417.88 C145H240N44O48S2 CCC(C)C(C(=O)NCC(=O)NC(C(C)C)C(=O)NCC(=O)NC(C)C(=O)N1CCCC1C(=O)N)NC(=O)C(C)NC(=O)C(C(C)O)NC(=O)C(CCC(=O)N)NC(=O)C2CCCN2C(=O)C(CC3=CC=CC=C3)NC(=O)C(C(C)O)NC(=O)C(CC4=CNC=N4)NC(=O)C(CC5=CC=CC=C5)NC(=O)C(CCCCN)NC(=O)C(CC(=O)N)NC(=O)C(CC6=CC=CC=C6)NC(=O)C(CC(=O)O)NC(=O)C(CCC(=O)N)NC(=O)C(C(C)O)NC(=O)C(CC7=CC=C(C=C7)O)NC(=O)C(C(C)O)NC(=O)CNC(=O)C(CC(C)C)NC(=O)C(CCSC)NC(=O)C8CSSCC(C(=O)NCC(=O)NC(C(=O)NC(C(=O)NC(C(=O)NC(C(=O)N8)C(C)O)CO)CC(C)C)CC(=O)N)N Protect from light.. Ambient -20°C Soluble in 5% acetic acid. "Tsagaraki I, Phenekos C, Tsilibary E, et al. Calcitonin-induced NF-κB activation up-regulates fibronectin expression in MG63 osteosarcoma cells. Anticancer Res. 2013 Nov;33(11):4901-6. PMID: 24222127.

 

Armagan O, Serin DK, Calisir C, et al. Inhalation therapy of calcitonin relieves osteoarthritis of the knee. J Korean Med Sci. 2012 Nov;27(11):1405-10. PMID: 23166425.

 

Kuo YJ, Tsuang FY, Sun JS, et al. Calcitonin inhibits SDCP-induced osteoclast apoptosis and increases its efficacy in a rat model of osteoporosis. PLoS One. 2012;7(7):e40272. PMID: 22792258.

" Not dangerous goods.

LKT C0148 Calcitonin, human 1 mg 276.2 Endogenous neuropeptide hormone, lowers extracellular Ca2+ levels. H-Cys-Gly-Asn-Leu-Ser-Thr-Cys-Met-Leu-Gly-Thr- Tyr-Thr-Gln-Asp-Phe-Asn-Lys-Phe-His-Thr-Phe-Pro-Gln-Thr-Ala-Ile-Gly-Val-Gly-Ala-Pro-NH2 Calcitonin M, human C carcinoma; hCT; Thyrocalcitonin 21215-62-3 ≥95% 3417.88 C145H240N44O48S2 CCC(C)C(C(=O)NCC(=O)NC(C(C)C)C(=O)NCC(=O)NC(C)C(=O)N1CCCC1C(=O)N)NC(=O)C(C)NC(=O)C(C(C)O)NC(=O)C(CCC(=O)N)NC(=O)C2CCCN2C(=O)C(CC3=CC=CC=C3)NC(=O)C(C(C)O)NC(=O)C(CC4=CNC=N4)NC(=O)C(CC5=CC=CC=C5)NC(=O)C(CCCCN)NC(=O)C(CC(=O)N)NC(=O)C(CC6=CC=CC=C6)NC(=O)C(CC(=O)O)NC(=O)C(CCC(=O)N)NC(=O)C(C(C)O)NC(=O)C(CC7=CC=C(C=C7)O)NC(=O)C(C(C)O)NC(=O)CNC(=O)C(CC(C)C)NC(=O)C(CCSC)NC(=O)C8CSSCC(C(=O)NCC(=O)NC(C(=O)NC(C(=O)NC(C(=O)NC(C(=O)N8)C(C)O)CO)CC(C)C)CC(=O)N)N Protect from light.. Ambient -20°C Soluble in 5% acetic acid. "Tsagaraki I, Phenekos C, Tsilibary E, et al. Calcitonin-induced NF-κB activation up-regulates fibronectin expression in MG63 osteosarcoma cells. Anticancer Res. 2013 Nov;33(11):4901-6. PMID: 24222127.

 

Armagan O, Serin DK, Calisir C, et al. Inhalation therapy of calcitonin relieves osteoarthritis of the knee. J Korean Med Sci. 2012 Nov;27(11):1405-10. PMID: 23166425.

 

Kuo YJ, Tsuang FY, Sun JS, et al. Calcitonin inhibits SDCP-induced osteoclast apoptosis and increases its efficacy in a rat model of osteoporosis. PLoS One. 2012;7(7):e40272. PMID: 22792258.

" Not dangerous goods.

LKT C0148 Calcitonin, human 2.5 mg 489.1 Endogenous neuropeptide hormone, lowers extracellular Ca2+ levels. H-Cys-Gly-Asn-Leu-Ser-Thr-Cys-Met-Leu-Gly-Thr- Tyr-Thr-Gln-Asp-Phe-Asn-Lys-Phe-His-Thr-Phe-Pro-Gln-Thr-Ala-Ile-Gly-Val-Gly-Ala-Pro-NH2 Calcitonin M, human C carcinoma; hCT; Thyrocalcitonin 21215-62-3 ≥95% 3417.88 C145H240N44O48S2 CCC(C)C(C(=O)NCC(=O)NC(C(C)C)C(=O)NCC(=O)NC(C)C(=O)N1CCCC1C(=O)N)NC(=O)C(C)NC(=O)C(C(C)O)NC(=O)C(CCC(=O)N)NC(=O)C2CCCN2C(=O)C(CC3=CC=CC=C3)NC(=O)C(C(C)O)NC(=O)C(CC4=CNC=N4)NC(=O)C(CC5=CC=CC=C5)NC(=O)C(CCCCN)NC(=O)C(CC(=O)N)NC(=O)C(CC6=CC=CC=C6)NC(=O)C(CC(=O)O)NC(=O)C(CCC(=O)N)NC(=O)C(C(C)O)NC(=O)C(CC7=CC=C(C=C7)O)NC(=O)C(C(C)O)NC(=O)CNC(=O)C(CC(C)C)NC(=O)C(CCSC)NC(=O)C8CSSCC(C(=O)NCC(=O)NC(C(=O)NC(C(=O)NC(C(=O)NC(C(=O)N8)C(C)O)CO)CC(C)C)CC(=O)N)N Protect from light.. Ambient -20°C Soluble in 5% acetic acid. "Tsagaraki I, Phenekos C, Tsilibary E, et al. Calcitonin-induced NF-κB activation up-regulates fibronectin expression in MG63 osteosarcoma cells. Anticancer Res. 2013 Nov;33(11):4901-6. PMID: 24222127.

 

Armagan O, Serin DK, Calisir C, et al. Inhalation therapy of calcitonin relieves osteoarthritis of the knee. J Korean Med Sci. 2012 Nov;27(11):1405-10. PMID: 23166425.

 

Kuo YJ, Tsuang FY, Sun JS, et al. Calcitonin inhibits SDCP-induced osteoclast apoptosis and increases its efficacy in a rat model of osteoporosis. PLoS One. 2012;7(7):e40272. PMID: 22792258.

" Not dangerous goods.

LKT C0149 Calcitonin, salmon 0.5 mg 134.9 Endogenous neuropeptide hormone, lowers extracellular Ca2+ levels. H-Cys-Ser-Asn-Leu-Ser-Thr-Cys-Val-Leu-Gly-Lys- Leu-Ser-Gln-Glu-Leu-His-Lys-Leu-Gln-Thr-Tyr-Pro-Arg-Thr-Asn-Thr-Gly-Ser-Gly-Thr-Pro-NH2 47931-85-1 ≥98% 3431.85 C151H226N40O45S3 CC(C)CC1C(=O)NC(C(=O)NC(C(=O)NC(CSSCC(C(=O)NC(C(=O)NC(C(=O)N1)CC(=O)N)CO)N)C(=O)NC(C(C)C)C(=O)NC(CC(C)C)C(=O)NCC(=O)NC(CCCCN)C(=O)NC(CC(C)C)C(=O)NC(CO)C(=O)NC(CCC(=O)N)C(=O)NC(CCC(=O)O)C(=O)NC(CC(C)C)C(=O)NC(CC2=CN=CN2)C(=O)NC(CCCCN)C(=O)NC(CC(C)C)C(=O)NC(CCC(=O)N)C(=O)NC(C(C)O)C(=O)NC(CC3=CC=C(C=C3)O)C(=O)N4CCCC4C(=O)NC(CCCNC(=N)N)C(=O)NC(C(C)O)C(=O)NC(CC(=O)N)C(=O)NC(C(C)O)C(=O)NCC(=O)NC(CO)C(=O)NCC(=O)NC(C(C)O)C(=O)N5CCCC5C(=O)N)C(C)O)CO Protect from light.. Ambient -20°C Soluble in 0.05M acetic acid and DMSO (10-20mg/mL). "Tsagaraki I, Phenekos C, Tsilibary E, et al. Calcitonin-induced NF-κB activation up-regulates fibronectin expression in MG63 osteosarcoma cells. Anticancer Res. 2013 Nov;33(11):4901-6. PMID: 24222127.

 

Armagan O, Serin DK, Calisir C, et al. Inhalation therapy of calcitonin relieves osteoarthritis of the knee. J Korean Med Sci. 2012 Nov;27(11):1405-10. PMID: 23166425.

 

Kuo YJ, Tsuang FY, Sun JS, et al. Calcitonin inhibits SDCP-induced osteoclast apoptosis and increases its efficacy in a rat model of osteoporosis. PLoS One. 2012;7(7):e40272. PMID: 22792258.

" Not dangerous goods.

LKT C0149 Calcitonin, salmon 1 mg 228 Endogenous neuropeptide hormone, lowers extracellular Ca2+ levels. H-Cys-Ser-Asn-Leu-Ser-Thr-Cys-Val-Leu-Gly-Lys- Leu-Ser-Gln-Glu-Leu-His-Lys-Leu-Gln-Thr-Tyr-Pro-Arg-Thr-Asn-Thr-Gly-Ser-Gly-Thr-Pro-NH2 47931-85-1 ≥98% 3431.85 C151H226N40O45S3 CC(C)CC1C(=O)NC(C(=O)NC(C(=O)NC(CSSCC(C(=O)NC(C(=O)NC(C(=O)N1)CC(=O)N)CO)N)C(=O)NC(C(C)C)C(=O)NC(CC(C)C)C(=O)NCC(=O)NC(CCCCN)C(=O)NC(CC(C)C)C(=O)NC(CO)C(=O)NC(CCC(=O)N)C(=O)NC(CCC(=O)O)C(=O)NC(CC(C)C)C(=O)NC(CC2=CN=CN2)C(=O)NC(CCCCN)C(=O)NC(CC(C)C)C(=O)NC(CCC(=O)N)C(=O)NC(C(C)O)C(=O)NC(CC3=CC=C(C=C3)O)C(=O)N4CCCC4C(=O)NC(CCCNC(=N)N)C(=O)NC(C(C)O)C(=O)NC(CC(=O)N)C(=O)NC(C(C)O)C(=O)NCC(=O)NC(CO)C(=O)NCC(=O)NC(C(C)O)C(=O)N5CCCC5C(=O)N)C(C)O)CO Protect from light.. Ambient -20°C Soluble in 0.05M acetic acid and DMSO (10-20mg/mL). "Tsagaraki I, Phenekos C, Tsilibary E, et al. Calcitonin-induced NF-κB activation up-regulates fibronectin expression in MG63 osteosarcoma cells. Anticancer Res. 2013 Nov;33(11):4901-6. PMID: 24222127.

 

Armagan O, Serin DK, Calisir C, et al. Inhalation therapy of calcitonin relieves osteoarthritis of the knee. J Korean Med Sci. 2012 Nov;27(11):1405-10. PMID: 23166425.

 

Kuo YJ, Tsuang FY, Sun JS, et al. Calcitonin inhibits SDCP-induced osteoclast apoptosis and increases its efficacy in a rat model of osteoporosis. PLoS One. 2012;7(7):e40272. PMID: 22792258.

" Not dangerous goods.

LKT C0149 Calcitonin, salmon 2.5 mg 401.9 Endogenous neuropeptide hormone, lowers extracellular Ca2+ levels. H-Cys-Ser-Asn-Leu-Ser-Thr-Cys-Val-Leu-Gly-Lys- Leu-Ser-Gln-Glu-Leu-His-Lys-Leu-Gln-Thr-Tyr-Pro-Arg-Thr-Asn-Thr-Gly-Ser-Gly-Thr-Pro-NH2 47931-85-1 ≥98% 3431.85 C151H226N40O45S3 CC(C)CC1C(=O)NC(C(=O)NC(C(=O)NC(CSSCC(C(=O)NC(C(=O)NC(C(=O)N1)CC(=O)N)CO)N)C(=O)NC(C(C)C)C(=O)NC(CC(C)C)C(=O)NCC(=O)NC(CCCCN)C(=O)NC(CC(C)C)C(=O)NC(CO)C(=O)NC(CCC(=O)N)C(=O)NC(CCC(=O)O)C(=O)NC(CC(C)C)C(=O)NC(CC2=CN=CN2)C(=O)NC(CCCCN)C(=O)NC(CC(C)C)C(=O)NC(CCC(=O)N)C(=O)NC(C(C)O)C(=O)NC(CC3=CC=C(C=C3)O)C(=O)N4CCCC4C(=O)NC(CCCNC(=N)N)C(=O)NC(C(C)O)C(=O)NC(CC(=O)N)C(=O)NC(C(C)O)C(=O)NCC(=O)NC(CO)C(=O)NCC(=O)NC(C(C)O)C(=O)N5CCCC5C(=O)N)C(C)O)CO Protect from light.. Ambient -20°C Soluble in 0.05M acetic acid and DMSO (10-20mg/mL). "Tsagaraki I, Phenekos C, Tsilibary E, et al. Calcitonin-induced NF-κB activation up-regulates fibronectin expression in MG63 osteosarcoma cells. Anticancer Res. 2013 Nov;33(11):4901-6. PMID: 24222127.

 

Armagan O, Serin DK, Calisir C, et al. Inhalation therapy of calcitonin relieves osteoarthritis of the knee. J Korean Med Sci. 2012 Nov;27(11):1405-10. PMID: 23166425.

 

Kuo YJ, Tsuang FY, Sun JS, et al. Calcitonin inhibits SDCP-induced osteoclast apoptosis and increases its efficacy in a rat model of osteoporosis. PLoS One. 2012;7(7):e40272. PMID: 22792258.

" Not dangerous goods.

LKT C0151 α-Calcitonin Gene Related Peptide, human 0.5 mg 300.1 Endogenous calcitonin-family peptide, involved in vasodilation and pain transmission; RAMP1 and CGRP agonist. alpha-CGRP; CGRP-I 90954-53-3 ≥95% 3789.31 C163H267N51O49S2 "CC(C)CC(C(=O)NC(CC(C)C)C(=O)NC(CO)C(=O)NC(CCCNC(=N)N)C(=O)NC(CO)C(=O)NCC(=O)NCC(=O)NC(C(C)C)C(=O)NC(C(C)C)C(=O)NC(CCCCN)C(=O)NC(CC(=O)N)C(=O)NC(CC(=O)N)C(=O)NC(Cc1ccccc1)C(=O)NC(C(C)C)C(=O)N2CCCC2C(=O)NC(C(C)O)C(=O)NC(CC(=O)N)C(=O)NC(C(C)C)C(=O)NCC(=O)NC(CO)C(=O)NC(CCCCN)C(=O)NC(C)C(=O)NC(Cc3ccccc3)C(=O)N)NC(=O)CNC(=O)C(C)NC(=O)C(CC(C)C)NC(=O)C(CCCNC(=N)N)NC(=O)C(Cc4cnc[nH]4)NC(=O)C(C(C)O)NC(=O)C(C(C)C)NC(=O)C(CS)NC(=O)C(C(C)O)NC(=O)C(C)NC(=O)C(C(C)O)NC(=O)C(CC(=O)O)NC(=O)C(CS)NC(=O)C(C)N

" Ambient -20°C Water (0.5 mg/ml) "Ma W, Zhang X, Shi S, et al. Neuropeptides stimulate human osteoblast activity and promote gap junctional intercellular communication. Neuropeptides. 2013 Jun;47(3):179-86. PMID: 23726661.

 

Yang JH, Zhang YQ, Guo Z. Endogenous CGRP protects retinal cells against stress induced apoptosis in rats. Neurosci Lett. 2011 Aug 26;501(2):83-5. PMID: 21763400.

 

Sink KS, Walker DL, Yang Y, et al. Calcitonin gene-related peptide in the bed nucleus of the stria terminalis produces an anxiety-like pattern of behavior and increases neural activation in anxiety-related structures. J Neurosci. 2011 Feb 2;31(5):1802-10. PMID: 21289190.

 

Mishima T, Ito Y, Hosono K, et al. Calcitonin gene-related peptide facilitates revascularization during hindlimb ischemia in mice. Am J Physiol Heart Circ Physiol. 2011 Feb;300(2):H431-9. PMID: 21131474.

 

Kroeger I, Erhardt A, Abt D, et al. The neuropeptide calcitonin gene-related peptide (CGRP) prevents inflammatory liver injury in mice. J Hepatol. 2009 Aug;51(2):342-53. PMID: 19464067.

" Not dangerous goods.

LKT C0151 α-Calcitonin Gene Related Peptide, human 1 mg 510 Endogenous calcitonin-family peptide, involved in vasodilation and pain transmission; RAMP1 and CGRP agonist. alpha-CGRP; CGRP-I 90954-53-3 ≥95% 3789.31 C163H267N51O49S2 "CC(C)CC(C(=O)NC(CC(C)C)C(=O)NC(CO)C(=O)NC(CCCNC(=N)N)C(=O)NC(CO)C(=O)NCC(=O)NCC(=O)NC(C(C)C)C(=O)NC(C(C)C)C(=O)NC(CCCCN)C(=O)NC(CC(=O)N)C(=O)NC(CC(=O)N)C(=O)NC(Cc1ccccc1)C(=O)NC(C(C)C)C(=O)N2CCCC2C(=O)NC(C(C)O)C(=O)NC(CC(=O)N)C(=O)NC(C(C)C)C(=O)NCC(=O)NC(CO)C(=O)NC(CCCCN)C(=O)NC(C)C(=O)NC(Cc3ccccc3)C(=O)N)NC(=O)CNC(=O)C(C)NC(=O)C(CC(C)C)NC(=O)C(CCCNC(=N)N)NC(=O)C(Cc4cnc[nH]4)NC(=O)C(C(C)O)NC(=O)C(C(C)C)NC(=O)C(CS)NC(=O)C(C(C)O)NC(=O)C(C)NC(=O)C(C(C)O)NC(=O)C(CC(=O)O)NC(=O)C(CS)NC(=O)C(C)N

" Ambient -20°C Water (0.5 mg/ml) "Ma W, Zhang X, Shi S, et al. Neuropeptides stimulate human osteoblast activity and promote gap junctional intercellular communication. Neuropeptides. 2013 Jun;47(3):179-86. PMID: 23726661.

 

Yang JH, Zhang YQ, Guo Z. Endogenous CGRP protects retinal cells against stress induced apoptosis in rats. Neurosci Lett. 2011 Aug 26;501(2):83-5. PMID: 21763400.

 

Sink KS, Walker DL, Yang Y, et al. Calcitonin gene-related peptide in the bed nucleus of the stria terminalis produces an anxiety-like pattern of behavior and increases neural activation in anxiety-related structures. J Neurosci. 2011 Feb 2;31(5):1802-10. PMID: 21289190.

 

Mishima T, Ito Y, Hosono K, et al. Calcitonin gene-related peptide facilitates revascularization during hindlimb ischemia in mice. Am J Physiol Heart Circ Physiol. 2011 Feb;300(2):H431-9. PMID: 21131474.

 

Kroeger I, Erhardt A, Abt D, et al. The neuropeptide calcitonin gene-related peptide (CGRP) prevents inflammatory liver injury in mice. J Hepatol. 2009 Aug;51(2):342-53. PMID: 19464067.

" Not dangerous goods.

LKT C0151 α-Calcitonin Gene Related Peptide, human 2.5 mg 900.1 Endogenous calcitonin-family peptide, involved in vasodilation and pain transmission; RAMP1 and CGRP agonist. alpha-CGRP; CGRP-I 90954-53-3 ≥95% 3789.31 C163H267N51O49S2 "CC(C)CC(C(=O)NC(CC(C)C)C(=O)NC(CO)C(=O)NC(CCCNC(=N)N)C(=O)NC(CO)C(=O)NCC(=O)NCC(=O)NC(C(C)C)C(=O)NC(C(C)C)C(=O)NC(CCCCN)C(=O)NC(CC(=O)N)C(=O)NC(CC(=O)N)C(=O)NC(Cc1ccccc1)C(=O)NC(C(C)C)C(=O)N2CCCC2C(=O)NC(C(C)O)C(=O)NC(CC(=O)N)C(=O)NC(C(C)C)C(=O)NCC(=O)NC(CO)C(=O)NC(CCCCN)C(=O)NC(C)C(=O)NC(Cc3ccccc3)C(=O)N)NC(=O)CNC(=O)C(C)NC(=O)C(CC(C)C)NC(=O)C(CCCNC(=N)N)NC(=O)C(Cc4cnc[nH]4)NC(=O)C(C(C)O)NC(=O)C(C(C)C)NC(=O)C(CS)NC(=O)C(C(C)O)NC(=O)C(C)NC(=O)C(C(C)O)NC(=O)C(CC(=O)O)NC(=O)C(CS)NC(=O)C(C)N

" Ambient -20°C Water (0.5 mg/ml) "Ma W, Zhang X, Shi S, et al. Neuropeptides stimulate human osteoblast activity and promote gap junctional intercellular communication. Neuropeptides. 2013 Jun;47(3):179-86. PMID: 23726661.

 

Yang JH, Zhang YQ, Guo Z. Endogenous CGRP protects retinal cells against stress induced apoptosis in rats. Neurosci Lett. 2011 Aug 26;501(2):83-5. PMID: 21763400.

 

Sink KS, Walker DL, Yang Y, et al. Calcitonin gene-related peptide in the bed nucleus of the stria terminalis produces an anxiety-like pattern of behavior and increases neural activation in anxiety-related structures. J Neurosci. 2011 Feb 2;31(5):1802-10. PMID: 21289190.

 

Mishima T, Ito Y, Hosono K, et al. Calcitonin gene-related peptide facilitates revascularization during hindlimb ischemia in mice. Am J Physiol Heart Circ Physiol. 2011 Feb;300(2):H431-9. PMID: 21131474.

 

Kroeger I, Erhardt A, Abt D, et al. The neuropeptide calcitonin gene-related peptide (CGRP) prevents inflammatory liver injury in mice. J Hepatol. 2009 Aug;51(2):342-53. PMID: 19464067.

" Not dangerous goods.

LKT C0152 9-Aminocamptothecin 10 mg 213.6 Camptothecin derivative; topoisomerase I inhibitor. 9-Amino-20-camptothecin; 9-AC 91421-43-1 ≥98% 363.37 C20H17N3O4 CCC1(C2=C(COC1=O)C(=O)N3CC4=C(C3=C2)N=C5C=CC=C(C5=C4)N)O Ambient -20°C Soluble in DMSO. "Rodríguez-Berna G, Mangas-Sanjuán V, Gonzalez-Alvarez M, et al. A promising camptothecin derivative: Semisynthesis, antitumor activity and intestinal permeability. Eur J Med Chem. 2014 Jun 25;83C:366-373. PMID: 24980118.

 

Berniak K, Rybak P, Bernas T, et al. Relationship between DNA damage response, initiated by camptothecin or oxidative stress, and DNA replication, analyzed by quantitative 3D image analysis. Cytometry A. 2013 Jul 11. [Epub ahead of print]. PMID: 23846844.

 

Redinbo MR, Stewart L, Kuhn P, et al. Crystal structures of human topoisomerase I in covalent and noncovalent complexes with DNA. Science. 1998 Mar 6;279(5356):1504-13. PMID: 9488644.

" Not dangerous goods.

LKT C0152 9-Aminocamptothecin 25 mg 444.9 Camptothecin derivative; topoisomerase I inhibitor. 9-Amino-20-camptothecin; 9-AC 91421-43-1 ≥98% 363.37 C20H17N3O4 CCC1(C2=C(COC1=O)C(=O)N3CC4=C(C3=C2)N=C5C=CC=C(C5=C4)N)O Ambient -20°C Soluble in DMSO. "Rodríguez-Berna G, Mangas-Sanjuán V, Gonzalez-Alvarez M, et al. A promising camptothecin derivative: Semisynthesis, antitumor activity and intestinal permeability. Eur J Med Chem. 2014 Jun 25;83C:366-373. PMID: 24980118.

 

Berniak K, Rybak P, Bernas T, et al. Relationship between DNA damage response, initiated by camptothecin or oxidative stress, and DNA replication, analyzed by quantitative 3D image analysis. Cytometry A. 2013 Jul 11. [Epub ahead of print]. PMID: 23846844.

 

Redinbo MR, Stewart L, Kuhn P, et al. Crystal structures of human topoisomerase I in covalent and noncovalent complexes with DNA. Science. 1998 Mar 6;279(5356):1504-13. PMID: 9488644.

" Not dangerous goods.

LKT C0152 9-Aminocamptothecin 50 mg 741.4 Camptothecin derivative; topoisomerase I inhibitor. 9-Amino-20-camptothecin; 9-AC 91421-43-1 ≥98% 363.37 C20H17N3O4 CCC1(C2=C(COC1=O)C(=O)N3CC4=C(C3=C2)N=C5C=CC=C(C5=C4)N)O Ambient -20°C Soluble in DMSO. "Rodríguez-Berna G, Mangas-Sanjuán V, Gonzalez-Alvarez M, et al. A promising camptothecin derivative: Semisynthesis, antitumor activity and intestinal permeability. Eur J Med Chem. 2014 Jun 25;83C:366-373. PMID: 24980118.

 

Berniak K, Rybak P, Bernas T, et al. Relationship between DNA damage response, initiated by camptothecin or oxidative stress, and DNA replication, analyzed by quantitative 3D image analysis. Cytometry A. 2013 Jul 11. [Epub ahead of print]. PMID: 23846844.

 

Redinbo MR, Stewart L, Kuhn P, et al. Crystal structures of human topoisomerase I in covalent and noncovalent complexes with DNA. Science. 1998 Mar 6;279(5356):1504-13. PMID: 9488644.

" Not dangerous goods.

LKT C0153 Calcitonin, rat 0.5 mg 162 Endogenous neuropeptide hormone, lowers extracellular Ca2+ levels. ≥95% 3399.9 C148H228N40O46S3 Ambient -20°C "Tsagaraki I, Phenekos C, Tsilibary E, et al. Calcitonin-induced NF-κB activation up-regulates fibronectin expression in MG63 osteosarcoma cells. Anticancer Res. 2013 Nov;33(11):4901-6. PMID: 24222127.

 

Armagan O, Serin DK, Calisir C, et al. Inhalation therapy of calcitonin relieves osteoarthritis of the knee. J Korean Med Sci. 2012 Nov;27(11):1405-10. PMID: 23166425.

 

Kuo YJ, Tsuang FY, Sun JS, et al. Calcitonin inhibits SDCP-induced osteoclast apoptosis and increases its efficacy in a rat model of osteoporosis. PLoS One. 2012;7(7):e40272. PMID: 22792258.

" Not dangerous goods.

LKT C0153 Calcitonin, rat 1 mg 276.2 Endogenous neuropeptide hormone, lowers extracellular Ca2+ levels. ≥95% 3399.9 C148H228N40O46S3 Ambient -20°C "Tsagaraki I, Phenekos C, Tsilibary E, et al. Calcitonin-induced NF-κB activation up-regulates fibronectin expression in MG63 osteosarcoma cells. Anticancer Res. 2013 Nov;33(11):4901-6. PMID: 24222127.

 

Armagan O, Serin DK, Calisir C, et al. Inhalation therapy of calcitonin relieves osteoarthritis of the knee. J Korean Med Sci. 2012 Nov;27(11):1405-10. PMID: 23166425.

 

Kuo YJ, Tsuang FY, Sun JS, et al. Calcitonin inhibits SDCP-induced osteoclast apoptosis and increases its efficacy in a rat model of osteoporosis. PLoS One. 2012;7(7):e40272. PMID: 22792258.

" Not dangerous goods.

LKT C0153 Calcitonin, rat 2.5 mg 489.1 Endogenous neuropeptide hormone, lowers extracellular Ca2+ levels. ≥95% 3399.9 C148H228N40O46S3 Ambient -20°C "Tsagaraki I, Phenekos C, Tsilibary E, et al. Calcitonin-induced NF-κB activation up-regulates fibronectin expression in MG63 osteosarcoma cells. Anticancer Res. 2013 Nov;33(11):4901-6. PMID: 24222127.

 

Armagan O, Serin DK, Calisir C, et al. Inhalation therapy of calcitonin relieves osteoarthritis of the knee. J Korean Med Sci. 2012 Nov;27(11):1405-10. PMID: 23166425.

 

Kuo YJ, Tsuang FY, Sun JS, et al. Calcitonin inhibits SDCP-induced osteoclast apoptosis and increases its efficacy in a rat model of osteoporosis. PLoS One. 2012;7(7):e40272. PMID: 22792258.

" Not dangerous goods.

LKT C0154 7-Ethyl-10-hydroxycamptothecin 10 mg 122.3 Camptothecin derivative; topoisomerase I inhibitor. 4,11-diethyl-4,9-dihydroxy-1H-Pyrano[3',4':6,7]- indolizino[1,2-b]quinoline-3,14(4H,12H)-dione SN-38; 7-ethyl-10-hydroxy-CPT 86639-52-3 ≥98% 392.4 C22H20N2O5 CCC1=C2C=C(C=CC2=NC3=C1CN4C3=CC5=C(C4=O)COC(=O)C5(CC)O)O Protect from light. Ambient -20°C "Rodríguez-Berna G, Mangas-Sanjuán V, Gonzalez-Alvarez M, et al. A promising camptothecin derivative: Semisynthesis, antitumor activity and intestinal permeability. Eur J Med Chem. 2014 Jun 25;83C:366-373. PMID: 24980118.

 

Berniak K, Rybak P, Bernas T, et al. Relationship between DNA damage response, initiated by camptothecin or oxidative stress, and DNA replication, analyzed by quantitative 3D image analysis. Cytometry A. 2013 Jul 11. [Epub ahead of print]. PMID: 23846844.

 

Redinbo MR, Stewart L, Kuhn P, et al. Crystal structures of human topoisomerase I in covalent and noncovalent complexes with DNA. Science. 1998 Mar 6;279(5356):1504-13. PMID: 9488644.

 

Blackwood E, Epler J, Yen I, et al. Combination drug scheduling defines a “window of opportunity” for chemopotentiation of gemcitabine by an orally bioavailable, selective ChK1 inhibitor, GNE-900. Mol Cancer Ther. 2013 Oct;12(10):1968-1980. PMID: 23873850.

 

Walton MI, Eve PD, Hayes A, et al. The preclinical pharmacology and therapeutic activity of the novel CHK1 inhibitor SAR-020106. Mol Cancer Ther. 2010 Jan;9(1):89-100. PMID: 20053762.

" T "UN number: 2811     Class: 6.1     Packing Group: III

Proper shipping name: Toxic solid, organic, n.o.s. (7-Ethyl-10-hydroxycamptothecin)

Marine pollutant:  No     Poison inhalation hazard:  No"

LKT C0154 7-Ethyl-10-hydroxycamptothecin 50 mg 475.7 Camptothecin derivative; topoisomerase I inhibitor. 4,11-diethyl-4,9-dihydroxy-1H-Pyrano[3',4':6,7]- indolizino[1,2-b]quinoline-3,14(4H,12H)-dione SN-38; 7-ethyl-10-hydroxy-CPT 86639-52-3 ≥98% 392.4 C22H20N2O5 CCC1=C2C=C(C=CC2=NC3=C1CN4C3=CC5=C(C4=O)COC(=O)C5(CC)O)O Protect from light. Ambient -20°C "Rodríguez-Berna G, Mangas-Sanjuán V, Gonzalez-Alvarez M, et al. A promising camptothecin derivative: Semisynthesis, antitumor activity and intestinal permeability. Eur J Med Chem. 2014 Jun 25;83C:366-373. PMID: 24980118.

 

Berniak K, Rybak P, Bernas T, et al. Relationship between DNA damage response, initiated by camptothecin or oxidative stress, and DNA replication, analyzed by quantitative 3D image analysis. Cytometry A. 2013 Jul 11. [Epub ahead of print]. PMID: 23846844.

 

Redinbo MR, Stewart L, Kuhn P, et al. Crystal structures of human topoisomerase I in covalent and noncovalent complexes with DNA. Science. 1998 Mar 6;279(5356):1504-13. PMID: 9488644.

 

Blackwood E, Epler J, Yen I, et al. Combination drug scheduling defines a “window of opportunity” for chemopotentiation of gemcitabine by an orally bioavailable, selective ChK1 inhibitor, GNE-900. Mol Cancer Ther. 2013 Oct;12(10):1968-1980. PMID: 23873850.

 

Walton MI, Eve PD, Hayes A, et al. The preclinical pharmacology and therapeutic activity of the novel CHK1 inhibitor SAR-020106. Mol Cancer Ther. 2010 Jan;9(1):89-100. PMID: 20053762.

" T "UN number: 2811     Class: 6.1     Packing Group: III

Proper shipping name: Toxic solid, organic, n.o.s. (7-Ethyl-10-hydroxycamptothecin)

Marine pollutant:  No     Poison inhalation hazard:  No"

LKT C0154 7-Ethyl-10-hydroxycamptothecin 100 mg 815.4 Camptothecin derivative; topoisomerase I inhibitor. 4,11-diethyl-4,9-dihydroxy-1H-Pyrano[3',4':6,7]- indolizino[1,2-b]quinoline-3,14(4H,12H)-dione SN-38; 7-ethyl-10-hydroxy-CPT 86639-52-3 ≥98% 392.4 C22H20N2O5 CCC1=C2C=C(C=CC2=NC3=C1CN4C3=CC5=C(C4=O)COC(=O)C5(CC)O)O Protect from light. Ambient -20°C "Rodríguez-Berna G, Mangas-Sanjuán V, Gonzalez-Alvarez M, et al. A promising camptothecin derivative: Semisynthesis, antitumor activity and intestinal permeability. Eur J Med Chem. 2014 Jun 25;83C:366-373. PMID: 24980118.

 

Berniak K, Rybak P, Bernas T, et al. Relationship between DNA damage response, initiated by camptothecin or oxidative stress, and DNA replication, analyzed by quantitative 3D image analysis. Cytometry A. 2013 Jul 11. [Epub ahead of print]. PMID: 23846844.

 

Redinbo MR, Stewart L, Kuhn P, et al. Crystal structures of human topoisomerase I in covalent and noncovalent complexes with DNA. Science. 1998 Mar 6;279(5356):1504-13. PMID: 9488644.

 

Blackwood E, Epler J, Yen I, et al. Combination drug scheduling defines a “window of opportunity” for chemopotentiation of gemcitabine by an orally bioavailable, selective ChK1 inhibitor, GNE-900. Mol Cancer Ther. 2013 Oct;12(10):1968-1980. PMID: 23873850.

 

Walton MI, Eve PD, Hayes A, et al. The preclinical pharmacology and therapeutic activity of the novel CHK1 inhibitor SAR-020106. Mol Cancer Ther. 2010 Jan;9(1):89-100. PMID: 20053762.

" T "UN number: 2811     Class: 6.1     Packing Group: III

Proper shipping name: Toxic solid, organic, n.o.s. (7-Ethyl-10-hydroxycamptothecin)

Marine pollutant:  No     Poison inhalation hazard:  No"

LKT Z3444 Zileuton 100 mg 83.7 5-Lipoxygenase inhibitor. 1-[1-(1-benzothiophen-2-yl)ethyl]-1-hydroxyurea 111406-87-2 ≥98% 236.29 C11H12N2O2S CC(C1=CC2=CC=CC=C2S1)N(C(=O)N)O Ambient Ambient >0.5 mg/ml in DMSO:PBS (pH 7.2) (1:1) "Meng Z, Cao R, Yang Z, et al. Inhibitor of 5-Lipoxygenase, Zileuton, Suppresses Prostate Cancer Metastasis by Upregulating E-cadherin and Paxillin. Urology. 2013 Dec;82(6):1452.e7-1452.e14. PMID: 24295266.

 

Chen WJ, Liaw SF, Lin CC, et al. Effects of zileuton on airway smooth muscle remodeling after repeated allergen challenge in brown norway rats. Respiration. 2013;86(5):421-9. PMID: 24021192.

 

Shi SS, Yang WZ, Tu XK, et al. 5-Lipoxygenase inhibitor zileuton inhibits neuronal apoptosis following focal cerebral ischemia. Inflammation. 2013 Dec;36(6):1209-17. PMID: 23695166

 

Chu J, Li JG, Praticò D. Zileuton improves memory deficits, amyloid and tau pathology in a mouse model of Alzheimer's disease with plaques and tangles. PLoS One. 2013 Aug 7;8(8):e70991. PMID: 23951061.

 

Chu J, Praticò D. 5-Lipoxygenase pharmacological blockade decreases tau phosphorylation in vivo: involvement of the cyclin-dependent kinase-5. Neurobiol Aging. 2013 Jun;34(6):1549-54. PMID: 23332172.

 

Rossi A, Pergola C, Koeberle A, et al. The 5-lipoxygenase inhibitor, zileuton, suppresses prostaglandin biosynthesis by inhibition of arachidonic acid release in macrophages. Br J Pharmacol. 2010 Oct;161(3):555-70. PMID: 20880396.

" Xn Not dangerous goods.

LKT Z3444 Zileuton 250 mg 167.4 5-Lipoxygenase inhibitor. 1-[1-(1-benzothiophen-2-yl)ethyl]-1-hydroxyurea 111406-87-2 ≥98% 236.29 C11H12N2O2S CC(C1=CC2=CC=CC=C2S1)N(C(=O)N)O Ambient Ambient >0.5 mg/ml in DMSO:PBS (pH 7.2) (1:1) "Meng Z, Cao R, Yang Z, et al. Inhibitor of 5-Lipoxygenase, Zileuton, Suppresses Prostate Cancer Metastasis by Upregulating E-cadherin and Paxillin. Urology. 2013 Dec;82(6):1452.e7-1452.e14. PMID: 24295266.

 

Chen WJ, Liaw SF, Lin CC, et al. Effects of zileuton on airway smooth muscle remodeling after repeated allergen challenge in brown norway rats. Respiration. 2013;86(5):421-9. PMID: 24021192.

 

Shi SS, Yang WZ, Tu XK, et al. 5-Lipoxygenase inhibitor zileuton inhibits neuronal apoptosis following focal cerebral ischemia. Inflammation. 2013 Dec;36(6):1209-17. PMID: 23695166

 

Chu J, Li JG, Praticò D. Zileuton improves memory deficits, amyloid and tau pathology in a mouse model of Alzheimer's disease with plaques and tangles. PLoS One. 2013 Aug 7;8(8):e70991. PMID: 23951061.

 

Chu J, Praticò D. 5-Lipoxygenase pharmacological blockade decreases tau phosphorylation in vivo: involvement of the cyclin-dependent kinase-5. Neurobiol Aging. 2013 Jun;34(6):1549-54. PMID: 23332172.

 

Rossi A, Pergola C, Koeberle A, et al. The 5-lipoxygenase inhibitor, zileuton, suppresses prostaglandin biosynthesis by inhibition of arachidonic acid release in macrophages. Br J Pharmacol. 2010 Oct;161(3):555-70. PMID: 20880396.

" Xn Not dangerous goods.

LKT Z3444 Zileuton 1 g 335 5-Lipoxygenase inhibitor. 1-[1-(1-benzothiophen-2-yl)ethyl]-1-hydroxyurea 111406-87-2 ≥98% 236.29 C11H12N2O2S CC(C1=CC2=CC=CC=C2S1)N(C(=O)N)O Ambient Ambient >0.5 mg/ml in DMSO:PBS (pH 7.2) (1:1) "Meng Z, Cao R, Yang Z, et al. Inhibitor of 5-Lipoxygenase, Zileuton, Suppresses Prostate Cancer Metastasis by Upregulating E-cadherin and Paxillin. Urology. 2013 Dec;82(6):1452.e7-1452.e14. PMID: 24295266.

 

Chen WJ, Liaw SF, Lin CC, et al. Effects of zileuton on airway smooth muscle remodeling after repeated allergen challenge in brown norway rats. Respiration. 2013;86(5):421-9. PMID: 24021192.

 

Shi SS, Yang WZ, Tu XK, et al. 5-Lipoxygenase inhibitor zileuton inhibits neuronal apoptosis following focal cerebral ischemia. Inflammation. 2013 Dec;36(6):1209-17. PMID: 23695166

 

Chu J, Li JG, Praticò D. Zileuton improves memory deficits, amyloid and tau pathology in a mouse model of Alzheimer's disease with plaques and tangles. PLoS One. 2013 Aug 7;8(8):e70991. PMID: 23951061.

 

Chu J, Praticò D. 5-Lipoxygenase pharmacological blockade decreases tau phosphorylation in vivo: involvement of the cyclin-dependent kinase-5. Neurobiol Aging. 2013 Jun;34(6):1549-54. PMID: 23332172.

 

Rossi A, Pergola C, Koeberle A, et al. The 5-lipoxygenase inhibitor, zileuton, suppresses prostaglandin biosynthesis by inhibition of arachidonic acid release in macrophages. Br J Pharmacol. 2010 Oct;161(3):555-70. PMID: 20880396.

" Xn Not dangerous goods.

LKT C0156 9-Nitro-20S-camptothecin 25 mg 96.2 Camptothecin derivative; topoisomerase I inhibitor. 9-Nitro-20(S)-Camptothecin Rubitecan, 9-nitrocamptothecin, 9-nitro-CPT 91421-42-0 ≥98% 393.35 C20H15N3O6 CCC1(C2=C(COC1=O)C(=O)N3CC4=C(C3=C2)N=C5C=CC=C(C5=C4)[N+](=O)[O-])O Ambient -20°C "Rodríguez-Berna G, Mangas-Sanjuán V, Gonzalez-Alvarez M, et al. A promising camptothecin derivative: Semisynthesis, antitumor activity and intestinal permeability. Eur J Med Chem. 2014 Jun 25;83C:366-373. PMID: 24980118.

 

Berniak K, Rybak P, Bernas T, et al. Relationship between DNA damage response, initiated by camptothecin or oxidative stress, and DNA replication, analyzed by quantitative 3D image analysis. Cytometry A. 2013 Jul 11. [Epub ahead of print]. PMID: 23846844.

 

Redinbo MR, Stewart L, Kuhn P, et al. Crystal structures of human topoisomerase I in covalent and noncovalent complexes with DNA. Science. 1998 Mar 6;279(5356):1504-13. PMID: 9488644.

" Not dangerous goods.

LKT C0156 9-Nitro-20S-camptothecin 50 mg 156.2 Camptothecin derivative; topoisomerase I inhibitor. 9-Nitro-20(S)-Camptothecin Rubitecan, 9-nitrocamptothecin, 9-nitro-CPT 91421-42-0 ≥98% 393.35 C20H15N3O6 CCC1(C2=C(COC1=O)C(=O)N3CC4=C(C3=C2)N=C5C=CC=C(C5=C4)[N+](=O)[O-])O Ambient -20°C "Rodríguez-Berna G, Mangas-Sanjuán V, Gonzalez-Alvarez M, et al. A promising camptothecin derivative: Semisynthesis, antitumor activity and intestinal permeability. Eur J Med Chem. 2014 Jun 25;83C:366-373. PMID: 24980118.

 

Berniak K, Rybak P, Bernas T, et al. Relationship between DNA damage response, initiated by camptothecin or oxidative stress, and DNA replication, analyzed by quantitative 3D image analysis. Cytometry A. 2013 Jul 11. [Epub ahead of print]. PMID: 23846844.

 

Redinbo MR, Stewart L, Kuhn P, et al. Crystal structures of human topoisomerase I in covalent and noncovalent complexes with DNA. Science. 1998 Mar 6;279(5356):1504-13. PMID: 9488644.

" Not dangerous goods.

LKT C0156 9-Nitro-20S-camptothecin 100 mg 251.5 Camptothecin derivative; topoisomerase I inhibitor. 9-Nitro-20(S)-Camptothecin Rubitecan, 9-nitrocamptothecin, 9-nitro-CPT 91421-42-0 ≥98% 393.35 C20H15N3O6 CCC1(C2=C(COC1=O)C(=O)N3CC4=C(C3=C2)N=C5C=CC=C(C5=C4)[N+](=O)[O-])O Ambient -20°C "Rodríguez-Berna G, Mangas-Sanjuán V, Gonzalez-Alvarez M, et al. A promising camptothecin derivative: Semisynthesis, antitumor activity and intestinal permeability. Eur J Med Chem. 2014 Jun 25;83C:366-373. PMID: 24980118.

 

Berniak K, Rybak P, Bernas T, et al. Relationship between DNA damage response, initiated by camptothecin or oxidative stress, and DNA replication, analyzed by quantitative 3D image analysis. Cytometry A. 2013 Jul 11. [Epub ahead of print]. PMID: 23846844.

 

Redinbo MR, Stewart L, Kuhn P, et al. Crystal structures of human topoisomerase I in covalent and noncovalent complexes with DNA. Science. 1998 Mar 6;279(5356):1504-13. PMID: 9488644.

" Not dangerous goods.

LKT C0160 Canrenone 1 g 57.8 Metabolite of spironolactone; Na+/K+ ATPase partial agonist, aldosterone and AR antagonist. (17α)-17-Hydroxy-3-oxo-pregna-4,6-diene-21- carboxylic acid γ-lactone Phanurane 976-71-6 ≥98% 340.46 C22H28O3 CC12CCC(=O)C=C1C=CC3C2CCC4(C3CCC45CCC(=O)O5)C Ambient 4°C "Cargnelli G, Trevisi L, Debetto P, et al. Effects of canrenone on aorta and right ventricle of the rat. J Cardiovasc Pharmacol. 2001 May;37(5):540-7. PMID: 11336105.

 

Corvol P, Claire M, Oblin ME, et al. Mechanism of the antimineralocorticoid effects of spirolactones. Kidney Int. 1981 Jul;20(1):1-6. PMID: 7029118.

" Not dangerous goods.

LKT C0160 Canrenone 5 g 173.3 Metabolite of spironolactone; Na+/K+ ATPase partial agonist, aldosterone and AR antagonist. (17α)-17-Hydroxy-3-oxo-pregna-4,6-diene-21- carboxylic acid γ-lactone Phanurane 976-71-6 ≥98% 340.46 C22H28O3 CC12CCC(=O)C=C1C=CC3C2CCC4(C3CCC45CCC(=O)O5)C Ambient 4°C "Cargnelli G, Trevisi L, Debetto P, et al. Effects of canrenone on aorta and right ventricle of the rat. J Cardiovasc Pharmacol. 2001 May;37(5):540-7. PMID: 11336105.

 

Corvol P, Claire M, Oblin ME, et al. Mechanism of the antimineralocorticoid effects of spirolactones. Kidney Int. 1981 Jul;20(1):1-6. PMID: 7029118.

" Not dangerous goods.

LKT C0160 Canrenone 25 g 693.2 Metabolite of spironolactone; Na+/K+ ATPase partial agonist, aldosterone and AR antagonist. (17α)-17-Hydroxy-3-oxo-pregna-4,6-diene-21- carboxylic acid γ-lactone Phanurane 976-71-6 ≥98% 340.46 C22H28O3 CC12CCC(=O)C=C1C=CC3C2CCC4(C3CCC45CCC(=O)O5)C Ambient 4°C "Cargnelli G, Trevisi L, Debetto P, et al. Effects of canrenone on aorta and right ventricle of the rat. J Cardiovasc Pharmacol. 2001 May;37(5):540-7. PMID: 11336105.

 

Corvol P, Claire M, Oblin ME, et al. Mechanism of the antimineralocorticoid effects of spirolactones. Kidney Int. 1981 Jul;20(1):1-6. PMID: 7029118.

" Not dangerous goods.

LKT C0162 Capecitabine 250 mg 67.9 5-FU prodrug; thymidylate synthase inhibitor. pentyl N-[1-[(2R,3R,4S,5R)-3,4-dihydroxy-5-methyloxolan-2-yl]-5-fluoro-2-oxopyrimidin-4-yl]carbamate 154361-50-9 ≥98% 359.35 C15H22FN3O6 CCCCCOC(=O)NC1=NC(=O)N(C=C1F)C2C(C(C(O2)C)O)O Ambient 4°C "Wilson PM, Fazzone W, LaBonte MJ, et al. Novel opportunities for thymidylate metabolism as a therapeutic target. Mol Cancer Ther. 2008 Sep;7(9):3029-37. PMID: 18790783.

 

Walko CM, Lindley C. Capecitabine: a review. Clin Ther. 2005 Jan;27(1):23-44. PMID: 15763604.

 

Ishikawa T, Utoh M, Sawada N, et al. Tumor selective delivery of 5-fluorouracil by capecitabine, a new oral fluoropyrimidine carbamate, in human cancer xenografts. Biochem Pharmacol. 1998 Apr 1;55(7):1091-7. PMID: 9605432.

" "UN number: 3077     Class: 9     Packing Group: III

Proper shipping name: Environmentally hazardous substance, solid, n.o.s. (Capecitabine)

Marine pollutant: Yes"

LKT C0162 Capecitabine 1 g 203.8 5-FU prodrug; thymidylate synthase inhibitor. pentyl N-[1-[(2R,3R,4S,5R)-3,4-dihydroxy-5-methyloxolan-2-yl]-5-fluoro-2-oxopyrimidin-4-yl]carbamate 154361-50-9 ≥98% 359.35 C15H22FN3O6 CCCCCOC(=O)NC1=NC(=O)N(C=C1F)C2C(C(C(O2)C)O)O Ambient 4°C "Wilson PM, Fazzone W, LaBonte MJ, et al. Novel opportunities for thymidylate metabolism as a therapeutic target. Mol Cancer Ther. 2008 Sep;7(9):3029-37. PMID: 18790783.

 

Walko CM, Lindley C. Capecitabine: a review. Clin Ther. 2005 Jan;27(1):23-44. PMID: 15763604.

 

Ishikawa T, Utoh M, Sawada N, et al. Tumor selective delivery of 5-fluorouracil by capecitabine, a new oral fluoropyrimidine carbamate, in human cancer xenografts. Biochem Pharmacol. 1998 Apr 1;55(7):1091-7. PMID: 9605432.

" "UN number: 3077     Class: 9     Packing Group: III

Proper shipping name: Environmentally hazardous substance, solid, n.o.s. (Capecitabine)

Marine pollutant: Yes"

LKT C0162 Capecitabine 5 g 652.3 5-FU prodrug; thymidylate synthase inhibitor. pentyl N-[1-[(2R,3R,4S,5R)-3,4-dihydroxy-5-methyloxolan-2-yl]-5-fluoro-2-oxopyrimidin-4-yl]carbamate 154361-50-9 ≥98% 359.35 C15H22FN3O6 CCCCCOC(=O)NC1=NC(=O)N(C=C1F)C2C(C(C(O2)C)O)O Ambient 4°C "Wilson PM, Fazzone W, LaBonte MJ, et al. Novel opportunities for thymidylate metabolism as a therapeutic target. Mol Cancer Ther. 2008 Sep;7(9):3029-37. PMID: 18790783.

 

Walko CM, Lindley C. Capecitabine: a review. Clin Ther. 2005 Jan;27(1):23-44. PMID: 15763604.

 

Ishikawa T, Utoh M, Sawada N, et al. Tumor selective delivery of 5-fluorouracil by capecitabine, a new oral fluoropyrimidine carbamate, in human cancer xenografts. Biochem Pharmacol. 1998 Apr 1;55(7):1091-7. PMID: 9605432.

" "UN number: 3077     Class: 9     Packing Group: III

Proper shipping name: Environmentally hazardous substance, solid, n.o.s. (Capecitabine)

Marine pollutant: Yes"

LKT Z2268 Z-FR-AMC 10 mg 276.2 Protease substrate. Z-FR-aminomethylcoumarin ≥95% 612.68 C33H36N6O6 Ambient -20°C Rieux A, Gras S, Lecaille F, et al. Eimeripain, a cathepsin B-like cysteine protease, expressed throughout sporulation of the apicomplexan parasite Eimeria tenella. PLoS One. 2012;7(3):e31914. PMID: 22457711. Not dangerous goods.

LKT Z2268 Z-FR-AMC 20 mg 468.2 Protease substrate. Z-FR-aminomethylcoumarin ≥95% 612.68 C33H36N6O6 Ambient -20°C Rieux A, Gras S, Lecaille F, et al. Eimeripain, a cathepsin B-like cysteine protease, expressed throughout sporulation of the apicomplexan parasite Eimeria tenella. PLoS One. 2012;7(3):e31914. PMID: 22457711. Not dangerous goods.

LKT Z2268 Z-FR-AMC 50 mg 828.1 Protease substrate. Z-FR-aminomethylcoumarin ≥95% 612.68 C33H36N6O6 Ambient -20°C Rieux A, Gras S, Lecaille F, et al. Eimeripain, a cathepsin B-like cysteine protease, expressed throughout sporulation of the apicomplexan parasite Eimeria tenella. PLoS One. 2012;7(3):e31914. PMID: 22457711. Not dangerous goods.

LKT Z1602 Zearalenone 1 mg 37.5 Mycotoxin produced by Fusarium; ER agonist. 17924-92-4 ≥98% 318.36 C18H22O5 CC1CCCC(=O)CCCC=CC2=CC(=CC(=C2C(=O)O1)O)O Ambient 4°C "Lee H, Kang C, Yoo YS, et al. Cytotoxicity and the induction of the stress protein Hsp 70 in Chang liver cells in response to zearalenone-induced oxidative stress. Environ Toxicol Pharmacol. 2013 Sep;36(2):732-40. PMID: 23917164.

 

Prouillac C, Koraichi F, Videmann B, et al. In vitro toxicological effects of estrogenic mycotoxins on human placental cells: structure activity relationships. Toxicol Appl Pharmacol. 2012 Mar 15;259(3):366-75. PMID: 22310176.

 

Kim IH, Son HY, Cho SW, et al. Zearalenone induces male germ cell apoptosis in rats. Toxicol Lett. 2003 Mar 3;138(3):185-92. PMID: 12565195.

 

Boyd PA, Wittliff JL. Mechanism of Fusarium mycotoxin action in mammary gland. J Toxicol Environ Health. 1978 Jan;4(1):1-8. PMID: 633402.

" C "UN number: 1759     Class: 8     Packing Group: III

Proper shipping name: Corrosive solid, n.o.s. (Zearalenone)"

LKT Z1602 Zearalenone 5 mg 74.6 Mycotoxin produced by Fusarium; ER agonist. 17924-92-4 ≥98% 318.36 C18H22O5 CC1CCCC(=O)CCCC=CC2=CC(=CC(=C2C(=O)O1)O)O Ambient 4°C "Lee H, Kang C, Yoo YS, et al. Cytotoxicity and the induction of the stress protein Hsp 70 in Chang liver cells in response to zearalenone-induced oxidative stress. Environ Toxicol Pharmacol. 2013 Sep;36(2):732-40. PMID: 23917164.

 

Prouillac C, Koraichi F, Videmann B, et al. In vitro toxicological effects of estrogenic mycotoxins on human placental cells: structure activity relationships. Toxicol Appl Pharmacol. 2012 Mar 15;259(3):366-75. PMID: 22310176.

 

Kim IH, Son HY, Cho SW, et al. Zearalenone induces male germ cell apoptosis in rats. Toxicol Lett. 2003 Mar 3;138(3):185-92. PMID: 12565195.

 

Boyd PA, Wittliff JL. Mechanism of Fusarium mycotoxin action in mammary gland. J Toxicol Environ Health. 1978 Jan;4(1):1-8. PMID: 633402.

" C "UN number: 1759     Class: 8     Packing Group: III

Proper shipping name: Corrosive solid, n.o.s. (Zearalenone)"

LKT Z1602 Zearalenone 10 mg 133.7 Mycotoxin produced by Fusarium; ER agonist. 17924-92-4 ≥98% 318.36 C18H22O5 CC1CCCC(=O)CCCC=CC2=CC(=CC(=C2C(=O)O1)O)O Ambient 4°C "Lee H, Kang C, Yoo YS, et al. Cytotoxicity and the induction of the stress protein Hsp 70 in Chang liver cells in response to zearalenone-induced oxidative stress. Environ Toxicol Pharmacol. 2013 Sep;36(2):732-40. PMID: 23917164.

 

Prouillac C, Koraichi F, Videmann B, et al. In vitro toxicological effects of estrogenic mycotoxins on human placental cells: structure activity relationships. Toxicol Appl Pharmacol. 2012 Mar 15;259(3):366-75. PMID: 22310176.

 

Kim IH, Son HY, Cho SW, et al. Zearalenone induces male germ cell apoptosis in rats. Toxicol Lett. 2003 Mar 3;138(3):185-92. PMID: 12565195.

 

Boyd PA, Wittliff JL. Mechanism of Fusarium mycotoxin action in mammary gland. J Toxicol Environ Health. 1978 Jan;4(1):1-8. PMID: 633402.

" C "UN number: 1759     Class: 8     Packing Group: III

Proper shipping name: Corrosive solid, n.o.s. (Zearalenone)"

LKT Z1216 Z-DEVD-AMC 5 mg 348 Caspase substrate. Ac-Asp-Glu-Val-Asp-7-amino-4-methylcoumarin; Z-DEVD-AMC ≥95% 767.73 C36H41N5O14 Ambient -20°C Pinto MC, Dias DF, Del Puerto HL, et al. Discovery of cytotoxic and pro-apoptotic compounds against leukemia cells: Tert-butyl-4-[(3-nitrophenoxy) methyl]-2,2-dimethyloxazolidine-3-carboxylate. Life Sci. 2011 Nov 21;89(21-22):786-94. PMID: 21983296. Not dangerous goods.

LKT Z1216 Z-DEVD-AMC 10 mg 591 Caspase substrate. Ac-Asp-Glu-Val-Asp-7-amino-4-methylcoumarin; Z-DEVD-AMC ≥95% 767.73 C36H41N5O14 Ambient -20°C Pinto MC, Dias DF, Del Puerto HL, et al. Discovery of cytotoxic and pro-apoptotic compounds against leukemia cells: Tert-butyl-4-[(3-nitrophenoxy) methyl]-2,2-dimethyloxazolidine-3-carboxylate. Life Sci. 2011 Nov 21;89(21-22):786-94. PMID: 21983296. Not dangerous goods.

LKT Z1216 Z-DEVD-AMC 25 mg 1043.9 Caspase substrate. Ac-Asp-Glu-Val-Asp-7-amino-4-methylcoumarin; Z-DEVD-AMC ≥95% 767.73 C36H41N5O14 Ambient -20°C Pinto MC, Dias DF, Del Puerto HL, et al. Discovery of cytotoxic and pro-apoptotic compounds against leukemia cells: Tert-butyl-4-[(3-nitrophenoxy) methyl]-2,2-dimethyloxazolidine-3-carboxylate. Life Sci. 2011 Nov 21;89(21-22):786-94. PMID: 21983296. Not dangerous goods.

LKT Z0146 Z-Ala-Ala-Leu-pNA 100 mg 149.9 Proteinase subtrate. 61043-33-2 ≥95% 527.6 C26H33N5O7 CC(C)CC(C(=O)NC1=CC=C(C=C1)[N+](=O)[O-])NC(=O)C(C)NC(=O)C(C)NC(=O)OCC2=CC=CC=C2 Ambient -20°C "Chou H, Tam MF, Lee LH, et al. Vacuolar serine protease is a major allergen of Cladosporium cladosporioides. Int Arch Allergy Immunol. 2008;146(4):277-86. PMID: 18362473.

 

Balaban NP, Malikova LA, Mardanova AM, et al. Purification and characterization of a subtilisin-like proteinases secreted in the stationary growth phase of Bacillus amyloliquefaciens H2. Biochemistry (Mosc). 2007 Apr;72(4):459-65. PMID: 17511612.

"

LKT Z0146 Z-Ala-Ala-Leu-pNA 250 mg 300.1 Proteinase subtrate. 61043-33-2 ≥95% 527.6 C26H33N5O7 CC(C)CC(C(=O)NC1=CC=C(C=C1)[N+](=O)[O-])NC(=O)C(C)NC(=O)C(C)NC(=O)OCC2=CC=CC=C2 Ambient -20°C "Chou H, Tam MF, Lee LH, et al. Vacuolar serine protease is a major allergen of Cladosporium cladosporioides. Int Arch Allergy Immunol. 2008;146(4):277-86. PMID: 18362473.

 

Balaban NP, Malikova LA, Mardanova AM, et al. Purification and characterization of a subtilisin-like proteinases secreted in the stationary growth phase of Bacillus amyloliquefaciens H2. Biochemistry (Mosc). 2007 Apr;72(4):459-65. PMID: 17511612.

"

LKT Y0052 Yangonin 5 mg 186.6 Dienolide kavalactone originally found in Piper methysticum (kava plant); CB1 agonist, GABA-A potentiator. (E)-4-Methoxy-6-[2-(4-methoxyphenyl)ethenyl]-2H- pyran-2-one 4-Methoxy-6-(β-(p-anisyl)vinyl)-α-pyrone 500-62-9 "≥98%

" 258.27 C15H14O4 COC1=CC=C(C=C1)C=CC2=CC(=CC(=O)O2)OC Ambient -20°C Practically insoluble in water. Soluble in hot alcohol, ethyl acetate and acetone. Slightly soluble in benzene or ether. "Ligresti A, Villano R, Allarà M, et al. Kavalactones and the endocannabinoid system: the plant-derived yangonin is a novel CB1 receptor ligand. Pharmacol Res. 2012 Aug;66(2):163-9. PMID: 22525682.

 

Wruck CJ, Götz ME, Herdegen T, et al. Kavalactones protect neural cells against amyloid beta peptide-induced neurotoxicity via extracellular signal-regulated kinase 1/2-dependent nuclear factor erythroid 2-related factor 2 activation. Mol Pharmacol. 2008 Jun;73(6):1785-95. PMID: 18334601.

 

Xuan TD, Elzaawely AA, Fukuta M, et al. Herbicidal and Fungicidal Activities of Lactones in Kava (Piper methysticum). J Agric Food Chem. 2006 Feb 8;54(3):720-5. PMID: 16448174.

 

Boonen G, Häberlein H. Influence of genuine kavapyrone enantiomers on the GABA-A binding site. Planta Med. 1998 Aug;64(6):504-6. PMID: 9776662.

" None Not dangerous goods.

LKT Y0052 Yangonin 10 mg 288.3 Dienolide kavalactone originally found in Piper methysticum (kava plant); CB1 agonist, GABA-A potentiator. (E)-4-Methoxy-6-[2-(4-methoxyphenyl)ethenyl]-2H- pyran-2-one 4-Methoxy-6-(β-(p-anisyl)vinyl)-α-pyrone 500-62-9 "≥98%

" 258.27 C15H14O4 COC1=CC=C(C=C1)C=CC2=CC(=CC(=O)O2)OC Ambient -20°C Practically insoluble in water. Soluble in hot alcohol, ethyl acetate and acetone. Slightly soluble in benzene or ether. "Ligresti A, Villano R, Allarà M, et al. Kavalactones and the endocannabinoid system: the plant-derived yangonin is a novel CB1 receptor ligand. Pharmacol Res. 2012 Aug;66(2):163-9. PMID: 22525682.

 

Wruck CJ, Götz ME, Herdegen T, et al. Kavalactones protect neural cells against amyloid beta peptide-induced neurotoxicity via extracellular signal-regulated kinase 1/2-dependent nuclear factor erythroid 2-related factor 2 activation. Mol Pharmacol. 2008 Jun;73(6):1785-95. PMID: 18334601.

 

Xuan TD, Elzaawely AA, Fukuta M, et al. Herbicidal and Fungicidal Activities of Lactones in Kava (Piper methysticum). J Agric Food Chem. 2006 Feb 8;54(3):720-5. PMID: 16448174.

 

Boonen G, Häberlein H. Influence of genuine kavapyrone enantiomers on the GABA-A binding site. Planta Med. 1998 Aug;64(6):504-6. PMID: 9776662.

" None Not dangerous goods.

LKT XX117 Non-Categorized 1 kit 153.8 Dry Ice -80°C

LKT "C0172

 

" Carbimazole 1 g 57.8 Methimazole prodrug; thyroid peroxidase inhibitor. 2,3-Dihydro-3-methyl-2-thioxo-1H-imidazole-1- carboxylic acid ethyl ester Athyromazole; Neo-mercazole; Neo-Thyreostat 22232-54-8 ≥98% 186.23 C7H10N2O2S CCOC(=O)N1C=CN(C1=S)C Ambient Ambient Soluble in water (500parts), ethanol (50parts), and chloroform (3parts). "Manna D, Roy G, Mugesh G. Antithyroid drugs and their analogues: synthesis, structure, and mechanism of action. Acc Chem Res. 2013 Nov 19;46(11):2706-15. PMID: 23883148.

 

Wilson R, McKillop JH, Buchanan LM, et al. The effect of carbimazole therapy on interleukin 2, interleukin 2 receptors and free radicals. Autoimmunity. 1990;8(1):3-7. PMID: 2129783.

" Xn Xi Not dangerous goods.

LKT C0172 Carbimazole 5 g 195.8 Methimazole prodrug; thyroid peroxidase inhibitor. 2,3-Dihydro-3-methyl-2-thioxo-1H-imidazole-1- carboxylic acid ethyl ester Athyromazole; Neo-mercazole; Neo-Thyreostat 22232-54-8 ≥98% 186.23 C7H10N2O2S CCOC(=O)N1C=CN(C1=S)C Ambient Ambient Soluble in water (500parts), ethanol (50parts), and chloroform (3parts). "Manna D, Roy G, Mugesh G. Antithyroid drugs and their analogues: synthesis, structure, and mechanism of action. Acc Chem Res. 2013 Nov 19;46(11):2706-15. PMID: 23883148.

 

Wilson R, McKillop JH, Buchanan LM, et al. The effect of carbimazole therapy on interleukin 2, interleukin 2 receptors and free radicals. Autoimmunity. 1990;8(1):3-7. PMID: 2129783.

" Xn Xi Not dangerous goods.

LKT C0172 Carbimazole 10 g 345.8 Methimazole prodrug; thyroid peroxidase inhibitor. 2,3-Dihydro-3-methyl-2-thioxo-1H-imidazole-1- carboxylic acid ethyl ester Athyromazole; Neo-mercazole; Neo-Thyreostat 22232-54-8 ≥98% 186.23 C7H10N2O2S CCOC(=O)N1C=CN(C1=S)C Ambient Ambient Soluble in water (500parts), ethanol (50parts), and chloroform (3parts). "Manna D, Roy G, Mugesh G. Antithyroid drugs and their analogues: synthesis, structure, and mechanism of action. Acc Chem Res. 2013 Nov 19;46(11):2706-15. PMID: 23883148.

 

Wilson R, McKillop JH, Buchanan LM, et al. The effect of carbimazole therapy on interleukin 2, interleukin 2 receptors and free radicals. Autoimmunity. 1990;8(1):3-7. PMID: 2129783.

" Xn Xi Not dangerous goods.

LKT XX116 Non-Categorized 1 kit 149.9 Dry Ice -80°C

LKT C0173 Carmustine 25 mg 69.2 Nitrosourea, DNA alkylator. N,N'-Bis(2-chloroethyl)-N-nitrosourea Becenun; Bicnu; Carmubris 154-93-8 ≥98% 214.05 C5H9Cl2N3O2 C(CCl)NC(=O)N(CCCl)N=O Ambient 4°C Soluble in water (4 mg/ml)or 50% ethanol (150 mg/ml). DMSO. "Zhang J, Chen M, Zhang Y, et al. Carmustine induces platelet apoptosis. Platelets. 2014 Jun 23:1-6. [Epub ahead of print]. PMID: 24955606.

 

Drabløs F, Feyzi E, Aas PA, et al. Alkylation damage in DNA and RNA--repair mechanisms and medical significance. DNA Repair (Amst). 2004 Nov 2;3(11):1389-407. PMID: 15380096.

" T+ "UN number: 2811     Class:  6.1     Packing group:  II

Proper shipping name:  Toxic solid, organic, n.o.s. (Carmustine)

Marine pollutant:  No     Poison inhalation hazard:  No"

LKT C0173 Carmustine 100 mg 259.6 Nitrosourea, DNA alkylator. N,N'-Bis(2-chloroethyl)-N-nitrosourea Becenun; Bicnu; Carmubris 154-93-8 ≥98% 214.05 C5H9Cl2N3O2 C(CCl)NC(=O)N(CCCl)N=O Ambient 4°C Soluble in water (4 mg/ml)or 50% ethanol (150 mg/ml). DMSO. "Zhang J, Chen M, Zhang Y, et al. Carmustine induces platelet apoptosis. Platelets. 2014 Jun 23:1-6. [Epub ahead of print]. PMID: 24955606.

 

Drabløs F, Feyzi E, Aas PA, et al. Alkylation damage in DNA and RNA--repair mechanisms and medical significance. DNA Repair (Amst). 2004 Nov 2;3(11):1389-407. PMID: 15380096.

" T+ "UN number: 2811     Class:  6.1     Packing group:  II

Proper shipping name:  Toxic solid, organic, n.o.s. (Carmustine)

Marine pollutant:  No     Poison inhalation hazard:  No"

LKT C0174 Carmofur 1 g 89.3 Pyrimidine analog, fluorouracil derivative; thymidylate synthase inhibitor. 5-Fluoro-N-hexyl-3,4-dihydro-2,4-1(2H)- pyrimidinecarboxamide HCFU; Mifurol; Yamaful 61422-45-5 ≥97% 257.26 C11H16FN3O3 CCCCCCNC(=O)N1C=C(C(=O)NC1=O)F Ambient 4°C "Pizzirani D, Pagliuca C, Realini N, et al. Discovery of a new class of highly potent inhibitors of acid ceramidase: synthesis and structure-activity relationship (SAR). J Med Chem. 2013 May 9;56(9):3518-30. PMID: 23614460.

 

Sakamoto J, Hamada C, Rahman M, et al. An individual patient data meta-analysis of adjuvant therapy with carmofur in patients with curatively resected colon cancer. Jpn J Clin Oncol. 2005 Sep;35(9):536-44. PMID: 16155120.

 

Morimoto K, Koh M. Postoperative adjuvant use of carmofur for early breast cancer. Osaka City Med J. 2003 Dec;49(2):77-83. PMID: 15179836.

 

Nakanishi H, Abe A, Inada K, et al. Induction of apoptosis in metastatic foci from human gastric cancer xenografts in nude mice and reduction of circulating tumor cells in blood by 5-FU and 1-hexylcarbamoyl-5-fluorouracil. J Cancer Res Clin Oncol. 1999 Dec;125(12):660-8. PMID: 10592098.

" Xi "UN number: 2811     Class: 6.1     Packing Group: II

Proper shipping name: Toxic solid, organic, n.o.s. (Carmofur)"

LKT C0174 Carmofur 5 g 381.3 Pyrimidine analog, fluorouracil derivative; thymidylate synthase inhibitor. 5-Fluoro-N-hexyl-3,4-dihydro-2,4-1(2H)- pyrimidinecarboxamide HCFU; Mifurol; Yamaful 61422-45-5 ≥97% 257.26 C11H16FN3O3 CCCCCCNC(=O)N1C=C(C(=O)NC1=O)F Ambient 4°C "Pizzirani D, Pagliuca C, Realini N, et al. Discovery of a new class of highly potent inhibitors of acid ceramidase: synthesis and structure-activity relationship (SAR). J Med Chem. 2013 May 9;56(9):3518-30. PMID: 23614460.

 

Sakamoto J, Hamada C, Rahman M, et al. An individual patient data meta-analysis of adjuvant therapy with carmofur in patients with curatively resected colon cancer. Jpn J Clin Oncol. 2005 Sep;35(9):536-44. PMID: 16155120.

 

Morimoto K, Koh M. Postoperative adjuvant use of carmofur for early breast cancer. Osaka City Med J. 2003 Dec;49(2):77-83. PMID: 15179836.

 

Nakanishi H, Abe A, Inada K, et al. Induction of apoptosis in metastatic foci from human gastric cancer xenografts in nude mice and reduction of circulating tumor cells in blood by 5-FU and 1-hexylcarbamoyl-5-fluorouracil. J Cancer Res Clin Oncol. 1999 Dec;125(12):660-8. PMID: 10592098.

" Xi "UN number: 2811     Class: 6.1     Packing Group: II

Proper shipping name: Toxic solid, organic, n.o.s. (Carmofur)"

LKT X1854 p-Xyleneselenocyanate 100 mg 93.8 Synthetic derivative of selenocyanate. 1,4-Phenylenebis(methylene)selenocyanate p-XSC 85539-83-9 ≥99% 314.1 C10H8N2Se2 CSCCNC(=O)N Ambient 4°C Soluble in DMSO. "Das JK, Sarkar S, Hossain SU, et al. Diphenylmethyl selenocyanate attenuates malachite green induced oxidative injury through antioxidation & inhibition of DNA damage in mice. Indian J Med Res. 2013 Jun;137(6):1163-73. PMID: 23852297.

 

Facompre ND, Sinha I, El-Bayoumy K, et al. Remarkable inhibition of mTOR signaling by the combination of rapamycin and 1,4-phenylenebis(methylene)selenocyanate in human prostate cancer cells. Int J Cancer. 2012 Nov 1;131(9):2134-42. PMID: 22307455.

 

Plano D, Baquedano Y, Moreno-Mateos D, et al. Selenocyanates and diselenides: a new class of potent antileishmanial agents. Eur J Med Chem. 2011 Aug;46(8):3315-23. PMID: 21571403.

 

Poerschke RL, Moos PJ. Thioredoxin reductase 1 knockdown enhances selenazolidine cytotoxicity in human lung cancer cells via mitochondrial dysfunction. Biochem Pharmacol. 2011 Jan 15;81(2):211-221. PMID: 20920480.

" Not dangerous goods.

LKT X1854 p-Xyleneselenocyanate 250 mg 187.4 Synthetic derivative of selenocyanate. 1,4-Phenylenebis(methylene)selenocyanate p-XSC 85539-83-9 ≥99% 314.1 C10H8N2Se2 CSCCNC(=O)N Ambient 4°C Soluble in DMSO. "Das JK, Sarkar S, Hossain SU, et al. Diphenylmethyl selenocyanate attenuates malachite green induced oxidative injury through antioxidation & inhibition of DNA damage in mice. Indian J Med Res. 2013 Jun;137(6):1163-73. PMID: 23852297.

 

Facompre ND, Sinha I, El-Bayoumy K, et al. Remarkable inhibition of mTOR signaling by the combination of rapamycin and 1,4-phenylenebis(methylene)selenocyanate in human prostate cancer cells. Int J Cancer. 2012 Nov 1;131(9):2134-42. PMID: 22307455.

 

Plano D, Baquedano Y, Moreno-Mateos D, et al. Selenocyanates and diselenides: a new class of potent antileishmanial agents. Eur J Med Chem. 2011 Aug;46(8):3315-23. PMID: 21571403.

 

Poerschke RL, Moos PJ. Thioredoxin reductase 1 knockdown enhances selenazolidine cytotoxicity in human lung cancer cells via mitochondrial dysfunction. Biochem Pharmacol. 2011 Jan 15;81(2):211-221. PMID: 20920480.

" Not dangerous goods.

LKT X1854 p-Xyleneselenocyanate 500 mg 326 Synthetic derivative of selenocyanate. 1,4-Phenylenebis(methylene)selenocyanate p-XSC 85539-83-9 ≥99% 314.1 C10H8N2Se2 CSCCNC(=O)N Ambient 4°C Soluble in DMSO. "Das JK, Sarkar S, Hossain SU, et al. Diphenylmethyl selenocyanate attenuates malachite green induced oxidative injury through antioxidation & inhibition of DNA damage in mice. Indian J Med Res. 2013 Jun;137(6):1163-73. PMID: 23852297.

 

Facompre ND, Sinha I, El-Bayoumy K, et al. Remarkable inhibition of mTOR signaling by the combination of rapamycin and 1,4-phenylenebis(methylene)selenocyanate in human prostate cancer cells. Int J Cancer. 2012 Nov 1;131(9):2134-42. PMID: 22307455.

 

Plano D, Baquedano Y, Moreno-Mateos D, et al. Selenocyanates and diselenides: a new class of potent antileishmanial agents. Eur J Med Chem. 2011 Aug;46(8):3315-23. PMID: 21571403.

 

Poerschke RL, Moos PJ. Thioredoxin reductase 1 knockdown enhances selenazolidine cytotoxicity in human lung cancer cells via mitochondrial dysfunction. Biochem Pharmacol. 2011 Jan 15;81(2):211-221. PMID: 20920480.

" Not dangerous goods.

LKT C0221 Caffeine 10 g 34.8 Xanthine alkaloid found in coffee, tea, and other plant sources; adenozine agonist, PDE inhibitor. 3,7-Dihydro-1,3,7-trimethyl-1H-purine-2,6-dione Coffeine; Thein; Guaranine; Methyltheobromine; No-Doz 58-08-2 ≥98% 194.19 C8H10N4O2 CN1C=NC2=C1C(=O)N(C(=O)N2C)C Solution of methanol or ethanol stored at 2-8°C stable for several years. Ambient Ambient Soluble in ethyl acetate or pyrrole. Slightly soluble in water (20 mg/mL), solubility is increased by adding dilute acid. Slightly soluble in ethanol (13 mg/mL). "Qi H, Li S. Dose-response meta-analysis on coffee, tea and caffeine consumption with risk of Parkinson's disease. Geriatr Gerontol Int. 2014 Apr;14(2):430-9. PMID: 23879665.

 

Gordillo-Bastidas D, Oceguera-Contreras E, Salazar-Montes A, et al. Nrf2 and Snail-1 in the prevention of experimental liver fibrosis by caffeine. World J Gastroenterol. 2013 Dec 21;19(47):9020-33. PMID: 24379627.

 

Herman A, Herman AP. Caffeine's mechanisms of action and its cosmetic use. Skin Pharmacol Physiol. 2013;26(1):8-14. PMID: 23075568.

 

Ribeiro JA, Sebastião AM. Caffeine and adenosine. J Alzheimers Dis. 2010;20 Suppl 1:S3-15. PMID: 20164566.

 

Welsh EJ, Bara A, Barley E, et al. Caffeine for asthma. Cochrane Database Syst Rev. 2010 Jan 20;(1):CD001112. PMID: 20091514.

" Xn, T Not dangerous goods.

LKT C0221 Caffeine 50 g 86.4 Xanthine alkaloid found in coffee, tea, and other plant sources; adenozine agonist, PDE inhibitor. 3,7-Dihydro-1,3,7-trimethyl-1H-purine-2,6-dione Coffeine; Thein; Guaranine; Methyltheobromine; No-Doz 58-08-2 ≥98% 194.19 C8H10N4O2 CN1C=NC2=C1C(=O)N(C(=O)N2C)C Solution of methanol or ethanol stored at 2-8°C stable for several years. Ambient Ambient Soluble in ethyl acetate or pyrrole. Slightly soluble in water (20 mg/mL), solubility is increased by adding dilute acid. Slightly soluble in ethanol (13 mg/mL). "Qi H, Li S. Dose-response meta-analysis on coffee, tea and caffeine consumption with risk of Parkinson's disease. Geriatr Gerontol Int. 2014 Apr;14(2):430-9. PMID: 23879665.

 

Gordillo-Bastidas D, Oceguera-Contreras E, Salazar-Montes A, et al. Nrf2 and Snail-1 in the prevention of experimental liver fibrosis by caffeine. World J Gastroenterol. 2013 Dec 21;19(47):9020-33. PMID: 24379627.

 

Herman A, Herman AP. Caffeine's mechanisms of action and its cosmetic use. Skin Pharmacol Physiol. 2013;26(1):8-14. PMID: 23075568.

 

Ribeiro JA, Sebastião AM. Caffeine and adenosine. J Alzheimers Dis. 2010;20 Suppl 1:S3-15. PMID: 20164566.

 

Welsh EJ, Bara A, Barley E, et al. Caffeine for asthma. Cochrane Database Syst Rev. 2010 Jan 20;(1):CD001112. PMID: 20091514.

" Xn, T Not dangerous goods.

LKT C0221 Caffeine 100 g 130 Xanthine alkaloid found in coffee, tea, and other plant sources; adenozine agonist, PDE inhibitor. 3,7-Dihydro-1,3,7-trimethyl-1H-purine-2,6-dione Coffeine; Thein; Guaranine; Methyltheobromine; No-Doz 58-08-2 ≥98% 194.19 C8H10N4O2 CN1C=NC2=C1C(=O)N(C(=O)N2C)C Solution of methanol or ethanol stored at 2-8°C stable for several years. Ambient Ambient Soluble in ethyl acetate or pyrrole. Slightly soluble in water (20 mg/mL), solubility is increased by adding dilute acid. Slightly soluble in ethanol (13 mg/mL). "Qi H, Li S. Dose-response meta-analysis on coffee, tea and caffeine consumption with risk of Parkinson's disease. Geriatr Gerontol Int. 2014 Apr;14(2):430-9. PMID: 23879665.

 

Gordillo-Bastidas D, Oceguera-Contreras E, Salazar-Montes A, et al. Nrf2 and Snail-1 in the prevention of experimental liver fibrosis by caffeine. World J Gastroenterol. 2013 Dec 21;19(47):9020-33. PMID: 24379627.

 

Herman A, Herman AP. Caffeine's mechanisms of action and its cosmetic use. Skin Pharmacol Physiol. 2013;26(1):8-14. PMID: 23075568.

 

Ribeiro JA, Sebastião AM. Caffeine and adenosine. J Alzheimers Dis. 2010;20 Suppl 1:S3-15. PMID: 20164566.

 

Welsh EJ, Bara A, Barley E, et al. Caffeine for asthma. Cochrane Database Syst Rev. 2010 Jan 20;(1):CD001112. PMID: 20091514.

" Xn, T Not dangerous goods.

LKT C0243 Calcitonin Gene Related Peptide (8-37), human 0.5 mg 228 Calcitonin-family peptide frgament, involved in vasodilation and pain transmission; RAMP1 and CGRP agonist. CGRP (8-37) 119911-68-1 ≥95% 3125.65 C139H230N44O38 "CC(C)CC(C(=O)NC(CC(C)C)C(=O)NC(CO)C(=O)NC(CCCNC(=N)N)C(=O)NC(CO)C(=O)NCC(=O)NCC(=O)NC(C(C)C)C(=O)NC(C(C)C)C(=O)NC(CCCCN)C(=O)NC(CC(=O)N)C(=O)NC(CC(=O)N)C(=O)NC(Cc1ccccc1)C(=O)NC(C(C)C)C(=O)N2CCCC2C(=O)NC(C(C)O)C(=O)NC(CC(=O)N)C(=O)NC(C(C)C)C(=O)NCC(=O)NC(CO)C(=O)NC(CCCCN)C(=O)NC(C)C(=O)NC(Cc3ccccc3)C(=O)N)NC(=O)CNC(=O)C(C)NC(=O)C(CC(C)C)NC(=O)C(CCCNC(=N)N)NC(=O)C(Cc4cnc[nH]4)NC(=O)C(C(C)O)NC(=O)C(C(C)C)N

" Ambient -20°C "Nguyen VT, Wu Y, Guillory AN, et al. Delta-opioid augments cardiac contraction through β-adrenergic and CGRP-receptor co-signaling. Peptides. 2012 Jan;33(1):77-82. PMID: 22108711.

 

Yang JH, Zhang YQ, Guo Z. Endogenous CGRP protects retinal cells against stress induced apoptosis in rats. Neurosci Lett. 2011 Aug 26;501(2):83-5. PMID: 21763400.

" Not dangerous goods.

LKT C0243 Calcitonin Gene Related Peptide (8-37), human 1 mg 387 Calcitonin-family peptide frgament, involved in vasodilation and pain transmission; RAMP1 and CGRP agonist. CGRP (8-37) 119911-68-1 ≥95% 3125.65 C139H230N44O38 "CC(C)CC(C(=O)NC(CC(C)C)C(=O)NC(CO)C(=O)NC(CCCNC(=N)N)C(=O)NC(CO)C(=O)NCC(=O)NCC(=O)NC(C(C)C)C(=O)NC(C(C)C)C(=O)NC(CCCCN)C(=O)NC(CC(=O)N)C(=O)NC(CC(=O)N)C(=O)NC(Cc1ccccc1)C(=O)NC(C(C)C)C(=O)N2CCCC2C(=O)NC(C(C)O)C(=O)NC(CC(=O)N)C(=O)NC(C(C)C)C(=O)NCC(=O)NC(CO)C(=O)NC(CCCCN)C(=O)NC(C)C(=O)NC(Cc3ccccc3)C(=O)N)NC(=O)CNC(=O)C(C)NC(=O)C(CC(C)C)NC(=O)C(CCCNC(=N)N)NC(=O)C(Cc4cnc[nH]4)NC(=O)C(C(C)O)NC(=O)C(C(C)C)N

" Ambient -20°C "Nguyen VT, Wu Y, Guillory AN, et al. Delta-opioid augments cardiac contraction through β-adrenergic and CGRP-receptor co-signaling. Peptides. 2012 Jan;33(1):77-82. PMID: 22108711.

 

Yang JH, Zhang YQ, Guo Z. Endogenous CGRP protects retinal cells against stress induced apoptosis in rats. Neurosci Lett. 2011 Aug 26;501(2):83-5. PMID: 21763400.

" Not dangerous goods.

LKT C0243 Calcitonin Gene Related Peptide (8-37), human 2.5 mg 684.1 Calcitonin-family peptide frgament, involved in vasodilation and pain transmission; RAMP1 and CGRP agonist. CGRP (8-37) 119911-68-1 ≥95% 3125.65 C139H230N44O38 "CC(C)CC(C(=O)NC(CC(C)C)C(=O)NC(CO)C(=O)NC(CCCNC(=N)N)C(=O)NC(CO)C(=O)NCC(=O)NCC(=O)NC(C(C)C)C(=O)NC(C(C)C)C(=O)NC(CCCCN)C(=O)NC(CC(=O)N)C(=O)NC(CC(=O)N)C(=O)NC(Cc1ccccc1)C(=O)NC(C(C)C)C(=O)N2CCCC2C(=O)NC(C(C)O)C(=O)NC(CC(=O)N)C(=O)NC(C(C)C)C(=O)NCC(=O)NC(CO)C(=O)NC(CCCCN)C(=O)NC(C)C(=O)NC(Cc3ccccc3)C(=O)N)NC(=O)CNC(=O)C(C)NC(=O)C(CC(C)C)NC(=O)C(CCCNC(=N)N)NC(=O)C(Cc4cnc[nH]4)NC(=O)C(C(C)O)NC(=O)C(C(C)C)N

" Ambient -20°C "Nguyen VT, Wu Y, Guillory AN, et al. Delta-opioid augments cardiac contraction through β-adrenergic and CGRP-receptor co-signaling. Peptides. 2012 Jan;33(1):77-82. PMID: 22108711.

 

Yang JH, Zhang YQ, Guo Z. Endogenous CGRP protects retinal cells against stress induced apoptosis in rats. Neurosci Lett. 2011 Aug 26;501(2):83-5. PMID: 21763400.

" Not dangerous goods.

LKT C0244 α-Calcitonin Gene Related Peptide, chicken 0.5 mg 300.1 Endogenous calcitonin-family peptide, involved in vasodilation and pain transmission; RAMP1 and CGRP agonist. CGRP ≥95% 3836.37 C165H260N52O50S2 Ambient -20°C "Ma W, Zhang X, Shi S, et al. Neuropeptides stimulate human osteoblast activity and promote gap junctional intercellular communication. Neuropeptides. 2013 Jun;47(3):179-86. PMID: 23726661.

 

Yang JH, Zhang YQ, Guo Z. Endogenous CGRP protects retinal cells against stress induced apoptosis in rats. Neurosci Lett. 2011 Aug 26;501(2):83-5. PMID: 21763400.

 

Sink KS, Walker DL, Yang Y, et al. Calcitonin gene-related peptide in the bed nucleus of the stria terminalis produces an anxiety-like pattern of behavior and increases neural activation in anxiety-related structures. J Neurosci. 2011 Feb 2;31(5):1802-10. PMID: 21289190.

 

Mishima T, Ito Y, Hosono K, et al. Calcitonin gene-related peptide facilitates revascularization during hindlimb ischemia in mice. Am J Physiol Heart Circ Physiol. 2011 Feb;300(2):H431-9. PMID: 21131474.

 

Kroeger I, Erhardt A, Abt D, et al. The neuropeptide calcitonin gene-related peptide (CGRP) prevents inflammatory liver injury in mice. J Hepatol. 2009 Aug;51(2):342-53. PMID: 19464067.

" Not dangerous goods.

LKT C0244 α-Calcitonin Gene Related Peptide, chicken 1 mg 510 Endogenous calcitonin-family peptide, involved in vasodilation and pain transmission; RAMP1 and CGRP agonist. CGRP ≥95% 3836.37 C165H260N52O50S2 Ambient -20°C "Ma W, Zhang X, Shi S, et al. Neuropeptides stimulate human osteoblast activity and promote gap junctional intercellular communication. Neuropeptides. 2013 Jun;47(3):179-86. PMID: 23726661.

 

Yang JH, Zhang YQ, Guo Z. Endogenous CGRP protects retinal cells against stress induced apoptosis in rats. Neurosci Lett. 2011 Aug 26;501(2):83-5. PMID: 21763400.

 

Sink KS, Walker DL, Yang Y, et al. Calcitonin gene-related peptide in the bed nucleus of the stria terminalis produces an anxiety-like pattern of behavior and increases neural activation in anxiety-related structures. J Neurosci. 2011 Feb 2;31(5):1802-10. PMID: 21289190.

 

Mishima T, Ito Y, Hosono K, et al. Calcitonin gene-related peptide facilitates revascularization during hindlimb ischemia in mice. Am J Physiol Heart Circ Physiol. 2011 Feb;300(2):H431-9. PMID: 21131474.

 

Kroeger I, Erhardt A, Abt D, et al. The neuropeptide calcitonin gene-related peptide (CGRP) prevents inflammatory liver injury in mice. J Hepatol. 2009 Aug;51(2):342-53. PMID: 19464067.

" Not dangerous goods.

LKT C0244 α-Calcitonin Gene Related Peptide, chicken 2.5 mg 900.1 Endogenous calcitonin-family peptide, involved in vasodilation and pain transmission; RAMP1 and CGRP agonist. CGRP ≥95% 3836.37 C165H260N52O50S2 Ambient -20°C "Ma W, Zhang X, Shi S, et al. Neuropeptides stimulate human osteoblast activity and promote gap junctional intercellular communication. Neuropeptides. 2013 Jun;47(3):179-86. PMID: 23726661.

 

Yang JH, Zhang YQ, Guo Z. Endogenous CGRP protects retinal cells against stress induced apoptosis in rats. Neurosci Lett. 2011 Aug 26;501(2):83-5. PMID: 21763400.

 

Sink KS, Walker DL, Yang Y, et al. Calcitonin gene-related peptide in the bed nucleus of the stria terminalis produces an anxiety-like pattern of behavior and increases neural activation in anxiety-related structures. J Neurosci. 2011 Feb 2;31(5):1802-10. PMID: 21289190.

 

Mishima T, Ito Y, Hosono K, et al. Calcitonin gene-related peptide facilitates revascularization during hindlimb ischemia in mice. Am J Physiol Heart Circ Physiol. 2011 Feb;300(2):H431-9. PMID: 21131474.

 

Kroeger I, Erhardt A, Abt D, et al. The neuropeptide calcitonin gene-related peptide (CGRP) prevents inflammatory liver injury in mice. J Hepatol. 2009 Aug;51(2):342-53. PMID: 19464067.

" Not dangerous goods.

LKT C0245 Calcitonin Gene Related Peptide, rat 0.5 mg 324 Endogenous calcitonin-family peptide, involved in vasodilation and pain transmission; RAMP1 and CGRP agonist. CGRP ≥95% 3806.33 C162H260N50O52S2 Ambient -20°C "Ma W, Zhang X, Shi S, et al. Neuropeptides stimulate human osteoblast activity and promote gap junctional intercellular communication. Neuropeptides. 2013 Jun;47(3):179-86. PMID: 23726661.

 

Yang JH, Zhang YQ, Guo Z. Endogenous CGRP protects retinal cells against stress induced apoptosis in rats. Neurosci Lett. 2011 Aug 26;501(2):83-5. PMID: 21763400.

 

Sink KS, Walker DL, Yang Y, et al. Calcitonin gene-related peptide in the bed nucleus of the stria terminalis produces an anxiety-like pattern of behavior and increases neural activation in anxiety-related structures. J Neurosci. 2011 Feb 2;31(5):1802-10. PMID: 21289190.

 

Mishima T, Ito Y, Hosono K, et al. Calcitonin gene-related peptide facilitates revascularization during hindlimb ischemia in mice. Am J Physiol Heart Circ Physiol. 2011 Feb;300(2):H431-9. PMID: 21131474.

 

Kroeger I, Erhardt A, Abt D, et al. The neuropeptide calcitonin gene-related peptide (CGRP) prevents inflammatory liver injury in mice. J Hepatol. 2009 Aug;51(2):342-53. PMID: 19464067.

" Not dangerous goods.

LKT C0245 Calcitonin Gene Related Peptide, rat 1 mg 552 Endogenous calcitonin-family peptide, involved in vasodilation and pain transmission; RAMP1 and CGRP agonist. CGRP ≥95% 3806.33 C162H260N50O52S2 Ambient -20°C "Ma W, Zhang X, Shi S, et al. Neuropeptides stimulate human osteoblast activity and promote gap junctional intercellular communication. Neuropeptides. 2013 Jun;47(3):179-86. PMID: 23726661.

 

Yang JH, Zhang YQ, Guo Z. Endogenous CGRP protects retinal cells against stress induced apoptosis in rats. Neurosci Lett. 2011 Aug 26;501(2):83-5. PMID: 21763400.

 

Sink KS, Walker DL, Yang Y, et al. Calcitonin gene-related peptide in the bed nucleus of the stria terminalis produces an anxiety-like pattern of behavior and increases neural activation in anxiety-related structures. J Neurosci. 2011 Feb 2;31(5):1802-10. PMID: 21289190.

 

Mishima T, Ito Y, Hosono K, et al. Calcitonin gene-related peptide facilitates revascularization during hindlimb ischemia in mice. Am J Physiol Heart Circ Physiol. 2011 Feb;300(2):H431-9. PMID: 21131474.

 

Kroeger I, Erhardt A, Abt D, et al. The neuropeptide calcitonin gene-related peptide (CGRP) prevents inflammatory liver injury in mice. J Hepatol. 2009 Aug;51(2):342-53. PMID: 19464067.

" Not dangerous goods.

LKT C0245 Calcitonin Gene Related Peptide, rat 2.5 mg 972.1 Endogenous calcitonin-family peptide, involved in vasodilation and pain transmission; RAMP1 and CGRP agonist. CGRP ≥95% 3806.33 C162H260N50O52S2 Ambient -20°C "Ma W, Zhang X, Shi S, et al. Neuropeptides stimulate human osteoblast activity and promote gap junctional intercellular communication. Neuropeptides. 2013 Jun;47(3):179-86. PMID: 23726661.

 

Yang JH, Zhang YQ, Guo Z. Endogenous CGRP protects retinal cells against stress induced apoptosis in rats. Neurosci Lett. 2011 Aug 26;501(2):83-5. PMID: 21763400.

 

Sink KS, Walker DL, Yang Y, et al. Calcitonin gene-related peptide in the bed nucleus of the stria terminalis produces an anxiety-like pattern of behavior and increases neural activation in anxiety-related structures. J Neurosci. 2011 Feb 2;31(5):1802-10. PMID: 21289190.

 

Mishima T, Ito Y, Hosono K, et al. Calcitonin gene-related peptide facilitates revascularization during hindlimb ischemia in mice. Am J Physiol Heart Circ Physiol. 2011 Feb;300(2):H431-9. PMID: 21131474.

 

Kroeger I, Erhardt A, Abt D, et al. The neuropeptide calcitonin gene-related peptide (CGRP) prevents inflammatory liver injury in mice. J Hepatol. 2009 Aug;51(2):342-53. PMID: 19464067.

" Not dangerous goods.

LKT C0246 Calcimycin 1 mg 40.7 Polyether pyrrole, divalent cation ionophore. 5-(Methylamino)-2-[[(2R,3R,6S,8S,9R,11R)-3,9,11- trimethyl-8-[(1S)-1-methyl-2-oxo-2-(1H-pyrrol-2-yl)- ethyl]-1,7-dioxaspiro[5.5]undec-2-yl]methyl]-4- benzoxazolecarboxylic acid Antibiotic A-23187; A-23187 52665-69-7 ≥98% 523.62 C29H37N3O6 CC1CCC2(C(CC(C(O2)C(C)C(=O)C3=CC=CN3)C)C)OC1CC4=NC5=C(O4)C=CC(=C5C(=O)O)NC Ambient -20°C Soluble in ethyl acetate, chloroform, methanol or DMSO. Slightly soluble in water. "Hosokawa J, Suzuki K, Nakagomi D, et al. Role of calcium ionophore A23187-induced activation of IkappaB kinase 2 in mast cells. Int Arch Allergy Immunol. 2013;161 Suppl 2:37-43. PMID: 23711852.

 

Abbott BJ, Fukuda DS, Dorman DE, et al. Microbial transformation of A23187, a divalent cation ionophore antibiotic. Antimicrob Agents Chemother. 1979 Dec;16(6):808-12. PMID: 119484.

" Xn Not dangerous goods.

LKT C0246 Calcimycin 5 mg 108.8 Polyether pyrrole, divalent cation ionophore. 5-(Methylamino)-2-[[(2R,3R,6S,8S,9R,11R)-3,9,11- trimethyl-8-[(1S)-1-methyl-2-oxo-2-(1H-pyrrol-2-yl)- ethyl]-1,7-dioxaspiro[5.5]undec-2-yl]methyl]-4- benzoxazolecarboxylic acid Antibiotic A-23187; A-23187 52665-69-7 ≥98% 523.62 C29H37N3O6 CC1CCC2(C(CC(C(O2)C(C)C(=O)C3=CC=CN3)C)C)OC1CC4=NC5=C(O4)C=CC(=C5C(=O)O)NC Ambient -20°C Soluble in ethyl acetate, chloroform, methanol or DMSO. Slightly soluble in water. "Hosokawa J, Suzuki K, Nakagomi D, et al. Role of calcium ionophore A23187-induced activation of IkappaB kinase 2 in mast cells. Int Arch Allergy Immunol. 2013;161 Suppl 2:37-43. PMID: 23711852.

 

Abbott BJ, Fukuda DS, Dorman DE, et al. Microbial transformation of A23187, a divalent cation ionophore antibiotic. Antimicrob Agents Chemother. 1979 Dec;16(6):808-12. PMID: 119484.

" Xn Not dangerous goods.

LKT C0246 Calcimycin 10 mg 169.9 Polyether pyrrole, divalent cation ionophore. 5-(Methylamino)-2-[[(2R,3R,6S,8S,9R,11R)-3,9,11- trimethyl-8-[(1S)-1-methyl-2-oxo-2-(1H-pyrrol-2-yl)- ethyl]-1,7-dioxaspiro[5.5]undec-2-yl]methyl]-4- benzoxazolecarboxylic acid Antibiotic A-23187; A-23187 52665-69-7 ≥98% 523.62 C29H37N3O6 CC1CCC2(C(CC(C(O2)C(C)C(=O)C3=CC=CN3)C)C)OC1CC4=NC5=C(O4)C=CC(=C5C(=O)O)NC Ambient -20°C Soluble in ethyl acetate, chloroform, methanol or DMSO. Slightly soluble in water. "Hosokawa J, Suzuki K, Nakagomi D, et al. Role of calcium ionophore A23187-induced activation of IkappaB kinase 2 in mast cells. Int Arch Allergy Immunol. 2013;161 Suppl 2:37-43. PMID: 23711852.

 

Abbott BJ, Fukuda DS, Dorman DE, et al. Microbial transformation of A23187, a divalent cation ionophore antibiotic. Antimicrob Agents Chemother. 1979 Dec;16(6):808-12. PMID: 119484.

" Xn Not dangerous goods.

LKT X1753 Xenopsin 1 mg 60 Peptide hormone, neurotensin analog found in amphibians. ≥95% 980.19 C47H73N13O10 CCC(C)C(C(=O)NC(CC(C)C)C(=O)O)NC(=O)C(CC1=CNC2=CC=CC=C21)NC(=O)C3CCCN3C(=O)C(CCCN=C(N)N)NC(=O)C(CCCCN)NC(=O)CNC(=O)C4CCC(=O)N4 Ambient -20°C "Zahid OK, Mechkarska M, Ojo OO, et al. Caerulein-and xenopsin-related peptides with insulin-releasing activities from skin secretions of the clawed frogs, Xenopus borealis and Xenopus amieti (Pipidae). Gen Comp Endocrinol. 2011 Jun 1;172(2):314-20. PMID: 21458457.

 

Clemens A, Katsoulis S, Nustede R, et al. Relaxant effect of xenin on rat ileum is mediated by apamin-sensitive neurotensin-type receptors. Am J Physiol. 1997 Jan;272(1 Pt 1):G190-6. PMID: 9038893.

 

Gao GC, Wei ET. Xenopsin, neurotensin, neurotensin(8-13) and N-acetyl-neurotensin(8-13) inhibit vascular leakage in rats after tissue injury. J Pharmacol Exp Ther. 1993 May;265(2):619-25. PMID: 8496813.

 

Feurle GE, Hamscher G, Kusiek R, et al. Identification of xenin, a xenopsin-related peptide, in the human gastric mucosa and its effect on exocrine pancreatic secretion. J Biol Chem. 1992 Nov 5;267(31):22305-9. PMID: 1429581.

 

Pozza MF, Küng E, Bischoff S, et al. The neurotensin analog xenopsin excites nigral dopamine neurons. Eur J Pharmacol. 1988 Jan 19;145(3):341-3. PMID: 3350051.

"

LKT X1753 Xenopsin 2 mg 101.9 Peptide hormone, neurotensin analog found in amphibians. ≥95% 980.19 C47H73N13O10 CCC(C)C(C(=O)NC(CC(C)C)C(=O)O)NC(=O)C(CC1=CNC2=CC=CC=C21)NC(=O)C3CCCN3C(=O)C(CCCN=C(N)N)NC(=O)C(CCCCN)NC(=O)CNC(=O)C4CCC(=O)N4 Ambient -20°C "Zahid OK, Mechkarska M, Ojo OO, et al. Caerulein-and xenopsin-related peptides with insulin-releasing activities from skin secretions of the clawed frogs, Xenopus borealis and Xenopus amieti (Pipidae). Gen Comp Endocrinol. 2011 Jun 1;172(2):314-20. PMID: 21458457.

 

Clemens A, Katsoulis S, Nustede R, et al. Relaxant effect of xenin on rat ileum is mediated by apamin-sensitive neurotensin-type receptors. Am J Physiol. 1997 Jan;272(1 Pt 1):G190-6. PMID: 9038893.

 

Gao GC, Wei ET. Xenopsin, neurotensin, neurotensin(8-13) and N-acetyl-neurotensin(8-13) inhibit vascular leakage in rats after tissue injury. J Pharmacol Exp Ther. 1993 May;265(2):619-25. PMID: 8496813.

 

Feurle GE, Hamscher G, Kusiek R, et al. Identification of xenin, a xenopsin-related peptide, in the human gastric mucosa and its effect on exocrine pancreatic secretion. J Biol Chem. 1992 Nov 5;267(31):22305-9. PMID: 1429581.

 

Pozza MF, Küng E, Bischoff S, et al. The neurotensin analog xenopsin excites nigral dopamine neurons. Eur J Pharmacol. 1988 Jan 19;145(3):341-3. PMID: 3350051.

"

LKT X1753 Xenopsin 5 mg 180 Peptide hormone, neurotensin analog found in amphibians. ≥95% 980.19 C47H73N13O10 CCC(C)C(C(=O)NC(CC(C)C)C(=O)O)NC(=O)C(CC1=CNC2=CC=CC=C21)NC(=O)C3CCCN3C(=O)C(CCCN=C(N)N)NC(=O)C(CCCCN)NC(=O)CNC(=O)C4CCC(=O)N4 Ambient -20°C "Zahid OK, Mechkarska M, Ojo OO, et al. Caerulein-and xenopsin-related peptides with insulin-releasing activities from skin secretions of the clawed frogs, Xenopus borealis and Xenopus amieti (Pipidae). Gen Comp Endocrinol. 2011 Jun 1;172(2):314-20. PMID: 21458457.

 

Clemens A, Katsoulis S, Nustede R, et al. Relaxant effect of xenin on rat ileum is mediated by apamin-sensitive neurotensin-type receptors. Am J Physiol. 1997 Jan;272(1 Pt 1):G190-6. PMID: 9038893.

 

Gao GC, Wei ET. Xenopsin, neurotensin, neurotensin(8-13) and N-acetyl-neurotensin(8-13) inhibit vascular leakage in rats after tissue injury. J Pharmacol Exp Ther. 1993 May;265(2):619-25. PMID: 8496813.

 

Feurle GE, Hamscher G, Kusiek R, et al. Identification of xenin, a xenopsin-related peptide, in the human gastric mucosa and its effect on exocrine pancreatic secretion. J Biol Chem. 1992 Nov 5;267(31):22305-9. PMID: 1429581.

 

Pozza MF, Küng E, Bischoff S, et al. The neurotensin analog xenopsin excites nigral dopamine neurons. Eur J Pharmacol. 1988 Jan 19;145(3):341-3. PMID: 3350051.

"

LKT C0247 Calcineurin Autoinhibitory Peptide 0.5 mg 168 Peptide; calcineurin inhibitor. ≥95% 2930.38 C124H205N39O39S2 CCC(C)C(C(=O)NC(C(C)O)C(=O)NC(CO)C(=O)NC(CC1=CC=CC=C1)C(=O)NC(CCC(=O)O)C(=O)NC(CCC(=O)O)C(=O)NC(C)C(=O)NC(CCCCN)C(=O)NCC(=O)NC(CC(C)C)C(=O)NC(CC(=O)O)C(=O)NC(CCCNC(=N)N)C(=O)NC(C(C)CC)C(=O)NC(CC(=O)N)C(=O)NC(CCC(=O)O)C(=O)NC(CCCNC(=N)N)C(=O)NC(CCSC)C(=O)N2CCCC2C(=O)N3CCCC3C(=O)NC(CCCNC(=N)N)C(=O)NC(CCCNC(=N)N)C(=O)NC(CC(=O)O)C(=O)NC(C)C(=O)NC(CCSC)C(=O)N4CCCC4C(=O)O)N Ambient -20°C "Terada H, Matsushita M, Lu YF, et al. Inhibition of excitatory neuronal cell death by cell-permeable calcineurin autoinhibitory peptide. J Neurochem. 2003 Dec;87(5):1145-51. PMID: 14622094.

 

Norris CM, Blalock EM, Chen KC, et al. Calcineurin enhances L-type Ca(2+) channel activity in hippocampal neurons: increased effect with age in culture. Neuroscience. 2002;110(2):213-25. PMID: 11958864.

 

Perrino BA. Regulation of calcineurin phosphatase activity by its autoinhibitory domain. Arch Biochem Biophys. 1999 Dec 1;372(1):159-65. PMID: 10562429.

" Not dangerous goods.

LKT C0247 Calcineurin Autoinhibitory Peptide 1 mg 285.1 Peptide; calcineurin inhibitor. ≥95% 2930.38 C124H205N39O39S2 CCC(C)C(C(=O)NC(C(C)O)C(=O)NC(CO)C(=O)NC(CC1=CC=CC=C1)C(=O)NC(CCC(=O)O)C(=O)NC(CCC(=O)O)C(=O)NC(C)C(=O)NC(CCCCN)C(=O)NCC(=O)NC(CC(C)C)C(=O)NC(CC(=O)O)C(=O)NC(CCCNC(=N)N)C(=O)NC(C(C)CC)C(=O)NC(CC(=O)N)C(=O)NC(CCC(=O)O)C(=O)NC(CCCNC(=N)N)C(=O)NC(CCSC)C(=O)N2CCCC2C(=O)N3CCCC3C(=O)NC(CCCNC(=N)N)C(=O)NC(CCCNC(=N)N)C(=O)NC(CC(=O)O)C(=O)NC(C)C(=O)NC(CCSC)C(=O)N4CCCC4C(=O)O)N Ambient -20°C "Terada H, Matsushita M, Lu YF, et al. Inhibition of excitatory neuronal cell death by cell-permeable calcineurin autoinhibitory peptide. J Neurochem. 2003 Dec;87(5):1145-51. PMID: 14622094.

 

Norris CM, Blalock EM, Chen KC, et al. Calcineurin enhances L-type Ca(2+) channel activity in hippocampal neurons: increased effect with age in culture. Neuroscience. 2002;110(2):213-25. PMID: 11958864.

 

Perrino BA. Regulation of calcineurin phosphatase activity by its autoinhibitory domain. Arch Biochem Biophys. 1999 Dec 1;372(1):159-65. PMID: 10562429.

" Not dangerous goods.

LKT C0247 Calcineurin Autoinhibitory Peptide 2.5 mg 504 Peptide; calcineurin inhibitor. ≥95% 2930.38 C124H205N39O39S2 CCC(C)C(C(=O)NC(C(C)O)C(=O)NC(CO)C(=O)NC(CC1=CC=CC=C1)C(=O)NC(CCC(=O)O)C(=O)NC(CCC(=O)O)C(=O)NC(C)C(=O)NC(CCCCN)C(=O)NCC(=O)NC(CC(C)C)C(=O)NC(CC(=O)O)C(=O)NC(CCCNC(=N)N)C(=O)NC(C(C)CC)C(=O)NC(CC(=O)N)C(=O)NC(CCC(=O)O)C(=O)NC(CCCNC(=N)N)C(=O)NC(CCSC)C(=O)N2CCCC2C(=O)N3CCCC3C(=O)NC(CCCNC(=N)N)C(=O)NC(CCCNC(=N)N)C(=O)NC(CC(=O)O)C(=O)NC(C)C(=O)NC(CCSC)C(=O)N4CCCC4C(=O)O)N Ambient -20°C "Terada H, Matsushita M, Lu YF, et al. Inhibition of excitatory neuronal cell death by cell-permeable calcineurin autoinhibitory peptide. J Neurochem. 2003 Dec;87(5):1145-51. PMID: 14622094.

 

Norris CM, Blalock EM, Chen KC, et al. Calcineurin enhances L-type Ca(2+) channel activity in hippocampal neurons: increased effect with age in culture. Neuroscience. 2002;110(2):213-25. PMID: 11958864.

 

Perrino BA. Regulation of calcineurin phosphatase activity by its autoinhibitory domain. Arch Biochem Biophys. 1999 Dec 1;372(1):159-65. PMID: 10562429.

" Not dangerous goods.

LKT C0248 Calcineurin Substrate 0.5 mg 149.9 Peptide used to measure in vitro calcineurin activity. H-Asp-Leu-Asp-Val-Pro-Ile-Pro-Gly-Arg-Phe-Asp-Arg-Arg-Val-Ser-Val-Ala-Ala-Glu-OH 113873-67-9 ≥96% 2112.4 C92H150N28O29S CCC(C)C(C(=O)N1CCCC1C(=O)NCC(=O)NC(CCCNC(=N)N)C(=O)NC(CC2=CC=CC=C2)C(=O)NC(CC(=O)O)C(=O)NC(CCCNC(=N)N)C(=O)NC(CCCNC(=N)N)C(=O)NC(C(C)C)C(=O)NC(CO)C(=O)NC(C(C)C)C(=O)NC(C)C(=O)NC(C)C(=O)NC(CCC(=O)O)C(=O)O)NC(=O)C3CCCN3C(=O)C(C(C)C)NC(=O)C(CC(=O)O)NC(=O)C(CC(C)C)NC(=O)C(CC(=O)O)N Ambient -20°C Soluble in water. "Namgaladze D, Hofer HW, Ullrich V. Redox control of calcineurin by targeting the binuclear Fe(2+)-Zn(2+) center at the enzyme active site. J Biol Chem. 2002 Feb 22;277(8):5962-9. PMID: 11741966.

 

Perrino BA, Fong YL, Brickey DA, et al. Characterization of the phosphatase activity of a baculovirus-expressed calcineurin A isoform. J Biol Chem. 1992 Aug 5;267(22):15965-9. PMID: 1322410.

" Not dangerous goods.

LKT C0248 Calcineurin Substrate 1 mg 255 Peptide used to measure in vitro calcineurin activity. H-Asp-Leu-Asp-Val-Pro-Ile-Pro-Gly-Arg-Phe-Asp-Arg-Arg-Val-Ser-Val-Ala-Ala-Glu-OH 113873-67-9 ≥96% 2112.4 C92H150N28O29S CCC(C)C(C(=O)N1CCCC1C(=O)NCC(=O)NC(CCCNC(=N)N)C(=O)NC(CC2=CC=CC=C2)C(=O)NC(CC(=O)O)C(=O)NC(CCCNC(=N)N)C(=O)NC(CCCNC(=N)N)C(=O)NC(C(C)C)C(=O)NC(CO)C(=O)NC(C(C)C)C(=O)NC(C)C(=O)NC(C)C(=O)NC(CCC(=O)O)C(=O)O)NC(=O)C3CCCN3C(=O)C(C(C)C)NC(=O)C(CC(=O)O)NC(=O)C(CC(C)C)NC(=O)C(CC(=O)O)N Ambient -20°C Soluble in water. "Namgaladze D, Hofer HW, Ullrich V. Redox control of calcineurin by targeting the binuclear Fe(2+)-Zn(2+) center at the enzyme active site. J Biol Chem. 2002 Feb 22;277(8):5962-9. PMID: 11741966.

 

Perrino BA, Fong YL, Brickey DA, et al. Characterization of the phosphatase activity of a baculovirus-expressed calcineurin A isoform. J Biol Chem. 1992 Aug 5;267(22):15965-9. PMID: 1322410.

" Not dangerous goods.

LKT C0248 Calcineurin Substrate 2.5 mg 450 Peptide used to measure in vitro calcineurin activity. H-Asp-Leu-Asp-Val-Pro-Ile-Pro-Gly-Arg-Phe-Asp-Arg-Arg-Val-Ser-Val-Ala-Ala-Glu-OH 113873-67-9 ≥96% 2112.4 C92H150N28O29S CCC(C)C(C(=O)N1CCCC1C(=O)NCC(=O)NC(CCCNC(=N)N)C(=O)NC(CC2=CC=CC=C2)C(=O)NC(CC(=O)O)C(=O)NC(CCCNC(=N)N)C(=O)NC(CCCNC(=N)N)C(=O)NC(C(C)C)C(=O)NC(CO)C(=O)NC(C(C)C)C(=O)NC(C)C(=O)NC(C)C(=O)NC(CCC(=O)O)C(=O)O)NC(=O)C3CCCN3C(=O)C(C(C)C)NC(=O)C(CC(=O)O)NC(=O)C(CC(C)C)NC(=O)C(CC(=O)O)N Ambient -20°C Soluble in water. "Namgaladze D, Hofer HW, Ullrich V. Redox control of calcineurin by targeting the binuclear Fe(2+)-Zn(2+) center at the enzyme active site. J Biol Chem. 2002 Feb 22;277(8):5962-9. PMID: 11741966.

 

Perrino BA, Fong YL, Brickey DA, et al. Characterization of the phosphatase activity of a baculovirus-expressed calcineurin A isoform. J Biol Chem. 1992 Aug 5;267(22):15965-9. PMID: 1322410.

" Not dangerous goods.

LKT X1752 Xenin 0.5 mg 228 Endogenous peptide hormone, neurotensin analog. ≥95% 2971.63 C139H224N38O32S1 CCC(C)C(C(=O)NC(CC(C)C)C(=O)O)NC(=O)C(CC1=CNC2=CC=CC=C21)NC(=O)C3CCCN3C(=O)C(CCCNC(=N)N)NC(=O)C(CCCCN)NC(=O)C4CCCN4C(=O)C(CC5=CN=CN5)NC(=O)C(CC6=CC=CC=C6)NC(=O)C(CO)NC(=O)C(CC(C)C)NC(=O)CNC(=O)C(CCCCN)NC(=O)C(C(C)C)NC(=O)C(CCCNC(=N)N)NC(=O)C(C)NC(=O)C(CO)NC(=O)C(CCCCN)NC(=O)C(C(C)O)NC(=O)C(CCC(=O)O)NC(=O)C(CC7=CC=CC=C7)NC(=O)C(CCCCN)NC(=O)C(C(C)O)NC(=O)C(CC(C)C)NC(=O)C(CCSC)N Ambient -20°C "Kim ER, Xu Y, Mizuno TM. Impaired suppression of feeding by the gut hormone xenin in type I interleukin-1 receptor-deficient mice. Behav Brain Res. 2013 Dec 12;261C:60-64. PMID: 24333379.

 

Kim ER, Mizuno TM. Xenin delays gastric emptying rate and activates the brainstem in mice. Neurosci Lett. 2010 Aug 30;481(1):59-63. PMID: 20599589.

 

Alexiou C, Zimmermann JP, Schick RR, et al. Xenin--a novel suppressor of food intake in rats. Brain Res. 1998 Aug 3;800(2):294-9. PMID: 9685684.

 

Clemens A, Katsoulis S, Nustede R, et al. Relaxant effect of xenin on rat ileum is mediated by apamin-sensitive neurotensin-type receptors. Am J Physiol. 1997 Jan;272(1 Pt 1):G190-6. PMID: 9038893.

"

LKT C0249 Calcitonin Gene Related Peptide (8-37), rat 0.5 mg 228 Endogenous calcitonin-family peptide frgament, involved in vasodilation and pain transmission; RAMP1 and CGRP agonist. CGRP (8-37) ≥95% 3127.58 C138H224N42O41 Ambient -20°C "Nguyen VT, Wu Y, Guillory AN, et al. Delta-opioid augments cardiac contraction through β-adrenergic and CGRP-receptor co-signaling. Peptides. 2012 Jan;33(1):77-82. PMID: 22108711.

 

Yang JH, Zhang YQ, Guo Z. Endogenous CGRP protects retinal cells against stress induced apoptosis in rats. Neurosci Lett. 2011 Aug 26;501(2):83-5. PMID: 21763400.

" Not dangerous goods.

LKT C0249 Calcitonin Gene Related Peptide (8-37), rat 1 mg 387 Endogenous calcitonin-family peptide frgament, involved in vasodilation and pain transmission; RAMP1 and CGRP agonist. CGRP (8-37) ≥95% 3127.58 C138H224N42O41 Ambient -20°C "Nguyen VT, Wu Y, Guillory AN, et al. Delta-opioid augments cardiac contraction through β-adrenergic and CGRP-receptor co-signaling. Peptides. 2012 Jan;33(1):77-82. PMID: 22108711.

 

Yang JH, Zhang YQ, Guo Z. Endogenous CGRP protects retinal cells against stress induced apoptosis in rats. Neurosci Lett. 2011 Aug 26;501(2):83-5. PMID: 21763400.

" Not dangerous goods.

LKT C0249 Calcitonin Gene Related Peptide (8-37), rat 2.5 mg 684.1 Endogenous calcitonin-family peptide frgament, involved in vasodilation and pain transmission; RAMP1 and CGRP agonist. CGRP (8-37) ≥95% 3127.58 C138H224N42O41 Ambient -20°C "Nguyen VT, Wu Y, Guillory AN, et al. Delta-opioid augments cardiac contraction through β-adrenergic and CGRP-receptor co-signaling. Peptides. 2012 Jan;33(1):77-82. PMID: 22108711.

 

Yang JH, Zhang YQ, Guo Z. Endogenous CGRP protects retinal cells against stress induced apoptosis in rats. Neurosci Lett. 2011 Aug 26;501(2):83-5. PMID: 21763400.

" Not dangerous goods.

LKT X1752 Xenin 1 mg 387 Endogenous peptide hormone, neurotensin analog. ≥95% 2971.63 C139H224N38O32S1 CCC(C)C(C(=O)NC(CC(C)C)C(=O)O)NC(=O)C(CC1=CNC2=CC=CC=C21)NC(=O)C3CCCN3C(=O)C(CCCNC(=N)N)NC(=O)C(CCCCN)NC(=O)C4CCCN4C(=O)C(CC5=CN=CN5)NC(=O)C(CC6=CC=CC=C6)NC(=O)C(CO)NC(=O)C(CC(C)C)NC(=O)CNC(=O)C(CCCCN)NC(=O)C(C(C)C)NC(=O)C(CCCNC(=N)N)NC(=O)C(C)NC(=O)C(CO)NC(=O)C(CCCCN)NC(=O)C(C(C)O)NC(=O)C(CCC(=O)O)NC(=O)C(CC7=CC=CC=C7)NC(=O)C(CCCCN)NC(=O)C(C(C)O)NC(=O)C(CC(C)C)NC(=O)C(CCSC)N Ambient -20°C "Kim ER, Xu Y, Mizuno TM. Impaired suppression of feeding by the gut hormone xenin in type I interleukin-1 receptor-deficient mice. Behav Brain Res. 2013 Dec 12;261C:60-64. PMID: 24333379.

 

Kim ER, Mizuno TM. Xenin delays gastric emptying rate and activates the brainstem in mice. Neurosci Lett. 2010 Aug 30;481(1):59-63. PMID: 20599589.

 

Alexiou C, Zimmermann JP, Schick RR, et al. Xenin--a novel suppressor of food intake in rats. Brain Res. 1998 Aug 3;800(2):294-9. PMID: 9685684.

 

Clemens A, Katsoulis S, Nustede R, et al. Relaxant effect of xenin on rat ileum is mediated by apamin-sensitive neurotensin-type receptors. Am J Physiol. 1997 Jan;272(1 Pt 1):G190-6. PMID: 9038893.

"

LKT X1752 Xenin 2.5 mg 684.1 Endogenous peptide hormone, neurotensin analog. ≥95% 2971.63 C139H224N38O32S1 CCC(C)C(C(=O)NC(CC(C)C)C(=O)O)NC(=O)C(CC1=CNC2=CC=CC=C21)NC(=O)C3CCCN3C(=O)C(CCCNC(=N)N)NC(=O)C(CCCCN)NC(=O)C4CCCN4C(=O)C(CC5=CN=CN5)NC(=O)C(CC6=CC=CC=C6)NC(=O)C(CO)NC(=O)C(CC(C)C)NC(=O)CNC(=O)C(CCCCN)NC(=O)C(C(C)C)NC(=O)C(CCCNC(=N)N)NC(=O)C(C)NC(=O)C(CO)NC(=O)C(CCCCN)NC(=O)C(C(C)O)NC(=O)C(CCC(=O)O)NC(=O)C(CC7=CC=CC=C7)NC(=O)C(CCCCN)NC(=O)C(C(C)O)NC(=O)C(CC(C)C)NC(=O)C(CCSC)N Ambient -20°C "Kim ER, Xu Y, Mizuno TM. Impaired suppression of feeding by the gut hormone xenin in type I interleukin-1 receptor-deficient mice. Behav Brain Res. 2013 Dec 12;261C:60-64. PMID: 24333379.

 

Kim ER, Mizuno TM. Xenin delays gastric emptying rate and activates the brainstem in mice. Neurosci Lett. 2010 Aug 30;481(1):59-63. PMID: 20599589.

 

Alexiou C, Zimmermann JP, Schick RR, et al. Xenin--a novel suppressor of food intake in rats. Brain Res. 1998 Aug 3;800(2):294-9. PMID: 9685684.

 

Clemens A, Katsoulis S, Nustede R, et al. Relaxant effect of xenin on rat ileum is mediated by apamin-sensitive neurotensin-type receptors. Am J Physiol. 1997 Jan;272(1 Pt 1):G190-6. PMID: 9038893.

"

LKT C0250 Calcitonin Gene Related Peptide II, human 0.5 mg 300.1 Calcitonin-family peptide, involved in vasodilation and gastric acid secretion; RAMP1 and CGRP agonist. CGRP II ≥95% 3793.38 C162H267N51O48S3 Ambient -20°C "Vanner S. Mechanism of action of capsaicin on submucosal arterioles in the guinea pig ileum. Am J Physiol. 1993 Jul;265(1 Pt 1):G51-5. PMID: 8338172.

 

Hernanz A, De Miguel E, Romera N, et al. Calcitonin gene-related peptide II, substance P and vasoactive intestinal peptide in plasma and synovial fluid from patients with inflammatory joint disease. Br J Rheumatol. 1993 Jan;32(1):31-5. PMID: 7678534.

 

Beglinger C, Born W, Hildebrand P, et al. Calcitonin gene-related peptides I and II and calcitonin: distinct effects on gastric acid secretion in humans. Gastroenterology. 1988 Oct;95(4):958-65. PMID: 2900791.

" Not dangerous goods.

LKT C0250 Calcitonin Gene Related Peptide II, human 1 mg 510 Calcitonin-family peptide, involved in vasodilation and gastric acid secretion; RAMP1 and CGRP agonist. CGRP II ≥95% 3793.38 C162H267N51O48S3 Ambient -20°C "Vanner S. Mechanism of action of capsaicin on submucosal arterioles in the guinea pig ileum. Am J Physiol. 1993 Jul;265(1 Pt 1):G51-5. PMID: 8338172.

 

Hernanz A, De Miguel E, Romera N, et al. Calcitonin gene-related peptide II, substance P and vasoactive intestinal peptide in plasma and synovial fluid from patients with inflammatory joint disease. Br J Rheumatol. 1993 Jan;32(1):31-5. PMID: 7678534.

 

Beglinger C, Born W, Hildebrand P, et al. Calcitonin gene-related peptides I and II and calcitonin: distinct effects on gastric acid secretion in humans. Gastroenterology. 1988 Oct;95(4):958-65. PMID: 2900791.

" Not dangerous goods.

LKT C0250 Calcitonin Gene Related Peptide II, human 2.5 mg 900.1 Calcitonin-family peptide, involved in vasodilation and gastric acid secretion; RAMP1 and CGRP agonist. CGRP II ≥95% 3793.38 C162H267N51O48S3 Ambient -20°C "Vanner S. Mechanism of action of capsaicin on submucosal arterioles in the guinea pig ileum. Am J Physiol. 1993 Jul;265(1 Pt 1):G51-5. PMID: 8338172.

 

Hernanz A, De Miguel E, Romera N, et al. Calcitonin gene-related peptide II, substance P and vasoactive intestinal peptide in plasma and synovial fluid from patients with inflammatory joint disease. Br J Rheumatol. 1993 Jan;32(1):31-5. PMID: 7678534.

 

Beglinger C, Born W, Hildebrand P, et al. Calcitonin gene-related peptides I and II and calcitonin: distinct effects on gastric acid secretion in humans. Gastroenterology. 1988 Oct;95(4):958-65. PMID: 2900791.

" Not dangerous goods.

LKT W5769 Wortmannin 1 mg 91.7 Steroid produced by Penicillum; PI3K, mTOR, DNA-PK, PI4K, MLCK, MAPK, PLK inhibitor. (1S,6bR,9aS,11R,11bR)-11-(Acetyloxy)-1,6b,7,8,9a,10,-11,11b-octahydro-1-(methoxymethyl)-9a,11b-dimethyl-3H-furo[4,3,2-de]ideno[4,5-h]-2-benzopyran-3,6,9- trione Wartmannin 19545-26-7 ≥97% 428.43 C23H24O8 CC(=O)OC1CC2(C(CCC2=O)C3=C1C4(C(OC(=O)C5=COC(=C54)C3=O)COC)C)C Unstable in aqueous solutions of pH 3-8. Dessicate. Ambient -20°C Soluble in methanol and DMSO. "Zhou X, Zhao Y, Xu L, et al. Wortmannin and U0126 inhibit the promoting effect of insulin on differentiation of skeletal myoblasts in rats. Xi Bao Yu Fen Zi Mian Yi Xue Za Zhi. 2014 Jul;30(7):717-20. PMID: 25001936.

 

Ji L, Zhang X, Liu W, et al. AMPK-regulated and Akt-dependent enhancement of glucose uptake is essential in ischemic preconditioning-alleviated reperfusion injury. PLoS One. 2013 Jul 26;8(7):e69910. PMID: 23922853.

 

Zaika O, Lara LS, Gamper N, et al. Angiotensin II regulates neuronal excitability via phosphatidylinositol 4,5-bisphosphate-dependent modulation of Kv7 (M-type) K+ channels. J Physiol. 2006 Aug 15;575(Pt 1):49-67. PMID: 16777936.

" T+ "UN number: 3462     Class: 6.1     Packing Group: I

Proper shipping name: Toxins, extracted from living sources, solid, n.o.s. (Wortmannin)"

LKT C0251 Calcitonin Gene Related Peptide II, rat 0.5 mg 300.1 Calcitonin-family peptide, involved in vasodilation and gastric acid secretion; RAMP1 and CGRP agonist. CGRP II ≥95% 3803.39 C163H265N51O50S2 Ambient -20°C "Vanner S. Mechanism of action of capsaicin on submucosal arterioles in the guinea pig ileum. Am J Physiol. 1993 Jul;265(1 Pt 1):G51-5. PMID: 8338172.

 

Hernanz A, De Miguel E, Romera N, et al. Calcitonin gene-related peptide II, substance P and vasoactive intestinal peptide in plasma and synovial fluid from patients with inflammatory joint disease. Br J Rheumatol. 1993 Jan;32(1):31-5. PMID: 7678534.

 

Beglinger C, Born W, Hildebrand P, et al. Calcitonin gene-related peptides I and II and calcitonin: distinct effects on gastric acid secretion in humans. Gastroenterology. 1988 Oct;95(4):958-65. PMID: 2900791.

" Not dangerous goods.

LKT C0251 Calcitonin Gene Related Peptide II, rat 1 mg 510 Calcitonin-family peptide, involved in vasodilation and gastric acid secretion; RAMP1 and CGRP agonist. CGRP II ≥95% 3803.39 C163H265N51O50S2 Ambient -20°C "Vanner S. Mechanism of action of capsaicin on submucosal arterioles in the guinea pig ileum. Am J Physiol. 1993 Jul;265(1 Pt 1):G51-5. PMID: 8338172.

 

Hernanz A, De Miguel E, Romera N, et al. Calcitonin gene-related peptide II, substance P and vasoactive intestinal peptide in plasma and synovial fluid from patients with inflammatory joint disease. Br J Rheumatol. 1993 Jan;32(1):31-5. PMID: 7678534.

 

Beglinger C, Born W, Hildebrand P, et al. Calcitonin gene-related peptides I and II and calcitonin: distinct effects on gastric acid secretion in humans. Gastroenterology. 1988 Oct;95(4):958-65. PMID: 2900791.

" Not dangerous goods.

LKT C0251 Calcitonin Gene Related Peptide II, rat 2.5 mg 900.1 Calcitonin-family peptide, involved in vasodilation and gastric acid secretion; RAMP1 and CGRP agonist. CGRP II ≥95% 3803.39 C163H265N51O50S2 Ambient -20°C "Vanner S. Mechanism of action of capsaicin on submucosal arterioles in the guinea pig ileum. Am J Physiol. 1993 Jul;265(1 Pt 1):G51-5. PMID: 8338172.

 

Hernanz A, De Miguel E, Romera N, et al. Calcitonin gene-related peptide II, substance P and vasoactive intestinal peptide in plasma and synovial fluid from patients with inflammatory joint disease. Br J Rheumatol. 1993 Jan;32(1):31-5. PMID: 7678534.

 

Beglinger C, Born W, Hildebrand P, et al. Calcitonin gene-related peptides I and II and calcitonin: distinct effects on gastric acid secretion in humans. Gastroenterology. 1988 Oct;95(4):958-65. PMID: 2900791.

" Not dangerous goods.

LKT W5769 Wortmannin 5 mg 362.1 Steroid produced by Penicillum; PI3K, mTOR, DNA-PK, PI4K, MLCK, MAPK, PLK inhibitor. (1S,6bR,9aS,11R,11bR)-11-(Acetyloxy)-1,6b,7,8,9a,10,-11,11b-octahydro-1-(methoxymethyl)-9a,11b-dimethyl-3H-furo[4,3,2-de]ideno[4,5-h]-2-benzopyran-3,6,9- trione Wartmannin 19545-26-7 ≥97% 428.43 C23H24O8 CC(=O)OC1CC2(C(CCC2=O)C3=C1C4(C(OC(=O)C5=COC(=C54)C3=O)COC)C)C Unstable in aqueous solutions of pH 3-8. Dessicate. Ambient -20°C Soluble in methanol and DMSO. "Zhou X, Zhao Y, Xu L, et al. Wortmannin and U0126 inhibit the promoting effect of insulin on differentiation of skeletal myoblasts in rats. Xi Bao Yu Fen Zi Mian Yi Xue Za Zhi. 2014 Jul;30(7):717-20. PMID: 25001936.

 

Ji L, Zhang X, Liu W, et al. AMPK-regulated and Akt-dependent enhancement of glucose uptake is essential in ischemic preconditioning-alleviated reperfusion injury. PLoS One. 2013 Jul 26;8(7):e69910. PMID: 23922853.

 

Zaika O, Lara LS, Gamper N, et al. Angiotensin II regulates neuronal excitability via phosphatidylinositol 4,5-bisphosphate-dependent modulation of Kv7 (M-type) K+ channels. J Physiol. 2006 Aug 15;575(Pt 1):49-67. PMID: 16777936.

" T+ "UN number: 3462     Class: 6.1     Packing Group: I

Proper shipping name: Toxins, extracted from living sources, solid, n.o.s. (Wortmannin)"

LKT C0253 Candesartan 100 mg 84.3 AT1 inhibitor. 2-ethoxy-3-[[4-[2-(2H-tetrazol-5-yl)phenyl]phenyl]methyl]benzimidazole-4-carboxylic acid 139481-59-7 ≥98% 440.45 C24H20N6O3 CCOC1=NC2=CC=CC(=C2N1CC3=CC=C(C=C3)C4=CC=CC=C4C5=NNN=N5)C(=O)O Ambient -20°C DMSO 88mg/mL "Patinha D, Fasching A, Pinho D, et al. Angiotensin II contributes to glomerular hyperfiltration in diabetic rats independently of adenosine type I receptors. Am J Physiol Renal Physiol. 2013 Mar 1;304(5):F614-22. PMID: 23283998.

 

Hu G, Li X, Sun X, et al. Identification of old drugs as potential inhibitors of HIV-1 integrase - human LEDGF/p75 interaction via molecular docking. J Mol Model. 2012 Dec;18(12):4995-5003. PMID: 22733274.

 

Nakamura S, Tsuruma K, Shimazawa M, et al. Candesartan, an angiotensin II type 1 receptor antagonist, inhibits pathological retinal neovascularization by downregulating VEGF receptor-2 expression. Eur J Pharmacol. 2012 Jun 15;685(1-3):8-14. PMID: 22543084.

 

Yu H, Zhao G, Li H, et al. Candesartan antagonizes pressure overload-evoked cardiac remodeling through Smad7 gene-dependent MMP-9 suppression. Gene. 2012 Apr 15;497(2):301-6. PMID: 22326534.

 

Yoshioka I, Tsujihata M, Akanae W, et al. Angiotensin type-1 receptor blocker candesartan inhibits calcium oxalate crystal deposition in ethylene glycol-treated rat kidneys. Urology. 2011 Apr;77(4):1007.e9-1007.e14. PMID: 21256551.

 

Wada T, Inada Y, Ojima M, et al. Comparison of the antihypertensive effects of the new angiotensin II (AT1) receptor antagonist candesartan cilexetil (TCV-116) and the angiotensin converting enzyme inhibitor enalapril in rats. Hypertens Res. 1996 Jun;19(2):75-81. Erratum in: Hypertens Res 1996 Sep;19(3):221. PMID: 10968199.

" Xn, Xi Not dangerous goods.

LKT C0253 Candesartan 250 mg 149.9 AT1 inhibitor. 2-ethoxy-3-[[4-[2-(2H-tetrazol-5-yl)phenyl]phenyl]methyl]benzimidazole-4-carboxylic acid 139481-59-7 ≥98% 440.45 C24H20N6O3 CCOC1=NC2=CC=CC(=C2N1CC3=CC=C(C=C3)C4=CC=CC=C4C5=NNN=N5)C(=O)O Ambient -20°C DMSO 88mg/mL "Patinha D, Fasching A, Pinho D, et al. Angiotensin II contributes to glomerular hyperfiltration in diabetic rats independently of adenosine type I receptors. Am J Physiol Renal Physiol. 2013 Mar 1;304(5):F614-22. PMID: 23283998.

 

Hu G, Li X, Sun X, et al. Identification of old drugs as potential inhibitors of HIV-1 integrase - human LEDGF/p75 interaction via molecular docking. J Mol Model. 2012 Dec;18(12):4995-5003. PMID: 22733274.

 

Nakamura S, Tsuruma K, Shimazawa M, et al. Candesartan, an angiotensin II type 1 receptor antagonist, inhibits pathological retinal neovascularization by downregulating VEGF receptor-2 expression. Eur J Pharmacol. 2012 Jun 15;685(1-3):8-14. PMID: 22543084.

 

Yu H, Zhao G, Li H, et al. Candesartan antagonizes pressure overload-evoked cardiac remodeling through Smad7 gene-dependent MMP-9 suppression. Gene. 2012 Apr 15;497(2):301-6. PMID: 22326534.

 

Yoshioka I, Tsujihata M, Akanae W, et al. Angiotensin type-1 receptor blocker candesartan inhibits calcium oxalate crystal deposition in ethylene glycol-treated rat kidneys. Urology. 2011 Apr;77(4):1007.e9-1007.e14. PMID: 21256551.

 

Wada T, Inada Y, Ojima M, et al. Comparison of the antihypertensive effects of the new angiotensin II (AT1) receptor antagonist candesartan cilexetil (TCV-116) and the angiotensin converting enzyme inhibitor enalapril in rats. Hypertens Res. 1996 Jun;19(2):75-81. Erratum in: Hypertens Res 1996 Sep;19(3):221. PMID: 10968199.

" Xn, Xi Not dangerous goods.

LKT C0253 Candesartan 1 g 468.8 AT1 inhibitor. 2-ethoxy-3-[[4-[2-(2H-tetrazol-5-yl)phenyl]phenyl]methyl]benzimidazole-4-carboxylic acid 139481-59-7 ≥98% 440.45 C24H20N6O3 CCOC1=NC2=CC=CC(=C2N1CC3=CC=C(C=C3)C4=CC=CC=C4C5=NNN=N5)C(=O)O Ambient -20°C DMSO 88mg/mL "Patinha D, Fasching A, Pinho D, et al. Angiotensin II contributes to glomerular hyperfiltration in diabetic rats independently of adenosine type I receptors. Am J Physiol Renal Physiol. 2013 Mar 1;304(5):F614-22. PMID: 23283998.

 

Hu G, Li X, Sun X, et al. Identification of old drugs as potential inhibitors of HIV-1 integrase - human LEDGF/p75 interaction via molecular docking. J Mol Model. 2012 Dec;18(12):4995-5003. PMID: 22733274.

 

Nakamura S, Tsuruma K, Shimazawa M, et al. Candesartan, an angiotensin II type 1 receptor antagonist, inhibits pathological retinal neovascularization by downregulating VEGF receptor-2 expression. Eur J Pharmacol. 2012 Jun 15;685(1-3):8-14. PMID: 22543084.

 

Yu H, Zhao G, Li H, et al. Candesartan antagonizes pressure overload-evoked cardiac remodeling through Smad7 gene-dependent MMP-9 suppression. Gene. 2012 Apr 15;497(2):301-6. PMID: 22326534.

 

Yoshioka I, Tsujihata M, Akanae W, et al. Angiotensin type-1 receptor blocker candesartan inhibits calcium oxalate crystal deposition in ethylene glycol-treated rat kidneys. Urology. 2011 Apr;77(4):1007.e9-1007.e14. PMID: 21256551.

 

Wada T, Inada Y, Ojima M, et al. Comparison of the antihypertensive effects of the new angiotensin II (AT1) receptor antagonist candesartan cilexetil (TCV-116) and the angiotensin converting enzyme inhibitor enalapril in rats. Hypertens Res. 1996 Jun;19(2):75-81. Erratum in: Hypertens Res 1996 Sep;19(3):221. PMID: 10968199.

" Xn, Xi Not dangerous goods.

LKT C0254 Candesartan Celexetil Ester 100 mg 67.2 AT1 inhibitor. Candesartan 1-[[(cyclohexyloxy)carbonyl]oxy]ethyl ester 145040-37-5 ≥98% 610.66 C33H34N6O6 CCOC1=NC2=CC=CC(=C2N1CC3=CC=C(C=C3)C4=CC=CC=C4C5=NNN=N5)C(=O)OC(C)OC(=O)OC6CCCCC6 Ambient Ambient Chloroform, slightly soluble in methanol, ethanol (3 mg/ml), DMSO (30 mg/ml). "Patinha D, Fasching A, Pinho D, et al. Angiotensin II contributes to glomerular hyperfiltration in diabetic rats independently of adenosine type I receptors. Am J Physiol Renal Physiol. 2013 Mar 1;304(5):F614-22. PMID: 23283998.

 

Hu G, Li X, Sun X, et al. Identification of old drugs as potential inhibitors of HIV-1 integrase - human LEDGF/p75 interaction via molecular docking. J Mol Model. 2012 Dec;18(12):4995-5003. PMID: 22733274.

 

Nakamura S, Tsuruma K, Shimazawa M, et al. Candesartan, an angiotensin II type 1 receptor antagonist, inhibits pathological retinal neovascularization by downregulating VEGF receptor-2 expression. Eur J Pharmacol. 2012 Jun 15;685(1-3):8-14. PMID: 22543084.

 

Yu H, Zhao G, Li H, et al. Candesartan antagonizes pressure overload-evoked cardiac remodeling through Smad7 gene-dependent MMP-9 suppression. Gene. 2012 Apr 15;497(2):301-6. PMID: 22326534.

 

Yoshioka I, Tsujihata M, Akanae W, et al. Angiotensin type-1 receptor blocker candesartan inhibits calcium oxalate crystal deposition in ethylene glycol-treated rat kidneys. Urology. 2011 Apr;77(4):1007.e9-1007.e14. PMID: 21256551.

 

Wada T, Inada Y, Ojima M, et al. Comparison of the antihypertensive effects of the new angiotensin II (AT1) receptor antagonist candesartan cilexetil (TCV-116) and the angiotensin converting enzyme inhibitor enalapril in rats. Hypertens Res. 1996 Jun;19(2):75-81. Erratum in: Hypertens Res 1996 Sep;19(3):221. PMID: 10968199.

" Xn, Xi Not dangerous goods.

LKT C0254 Candesartan Celexetil Ester 250 mg 119.7 AT1 inhibitor. Candesartan 1-[[(cyclohexyloxy)carbonyl]oxy]ethyl ester 145040-37-5 ≥98% 610.66 C33H34N6O6 CCOC1=NC2=CC=CC(=C2N1CC3=CC=C(C=C3)C4=CC=CC=C4C5=NNN=N5)C(=O)OC(C)OC(=O)OC6CCCCC6 Ambient Ambient Chloroform, slightly soluble in methanol, ethanol (3 mg/ml), DMSO (30 mg/ml). "Patinha D, Fasching A, Pinho D, et al. Angiotensin II contributes to glomerular hyperfiltration in diabetic rats independently of adenosine type I receptors. Am J Physiol Renal Physiol. 2013 Mar 1;304(5):F614-22. PMID: 23283998.

 

Hu G, Li X, Sun X, et al. Identification of old drugs as potential inhibitors of HIV-1 integrase - human LEDGF/p75 interaction via molecular docking. J Mol Model. 2012 Dec;18(12):4995-5003. PMID: 22733274.

 

Nakamura S, Tsuruma K, Shimazawa M, et al. Candesartan, an angiotensin II type 1 receptor antagonist, inhibits pathological retinal neovascularization by downregulating VEGF receptor-2 expression. Eur J Pharmacol. 2012 Jun 15;685(1-3):8-14. PMID: 22543084.

 

Yu H, Zhao G, Li H, et al. Candesartan antagonizes pressure overload-evoked cardiac remodeling through Smad7 gene-dependent MMP-9 suppression. Gene. 2012 Apr 15;497(2):301-6. PMID: 22326534.

 

Yoshioka I, Tsujihata M, Akanae W, et al. Angiotensin type-1 receptor blocker candesartan inhibits calcium oxalate crystal deposition in ethylene glycol-treated rat kidneys. Urology. 2011 Apr;77(4):1007.e9-1007.e14. PMID: 21256551.

 

Wada T, Inada Y, Ojima M, et al. Comparison of the antihypertensive effects of the new angiotensin II (AT1) receptor antagonist candesartan cilexetil (TCV-116) and the angiotensin converting enzyme inhibitor enalapril in rats. Hypertens Res. 1996 Jun;19(2):75-81. Erratum in: Hypertens Res 1996 Sep;19(3):221. PMID: 10968199.

" Xn, Xi Not dangerous goods.

LKT C0254 Candesartan Celexetil Ester 1 g 364 AT1 inhibitor. Candesartan 1-[[(cyclohexyloxy)carbonyl]oxy]ethyl ester 145040-37-5 ≥98% 610.66 C33H34N6O6 CCOC1=NC2=CC=CC(=C2N1CC3=CC=C(C=C3)C4=CC=CC=C4C5=NNN=N5)C(=O)OC(C)OC(=O)OC6CCCCC6 Ambient Ambient Chloroform, slightly soluble in methanol, ethanol (3 mg/ml), DMSO (30 mg/ml). "Patinha D, Fasching A, Pinho D, et al. Angiotensin II contributes to glomerular hyperfiltration in diabetic rats independently of adenosine type I receptors. Am J Physiol Renal Physiol. 2013 Mar 1;304(5):F614-22. PMID: 23283998.

 

Hu G, Li X, Sun X, et al. Identification of old drugs as potential inhibitors of HIV-1 integrase - human LEDGF/p75 interaction via molecular docking. J Mol Model. 2012 Dec;18(12):4995-5003. PMID: 22733274.

 

Nakamura S, Tsuruma K, Shimazawa M, et al. Candesartan, an angiotensin II type 1 receptor antagonist, inhibits pathological retinal neovascularization by downregulating VEGF receptor-2 expression. Eur J Pharmacol. 2012 Jun 15;685(1-3):8-14. PMID: 22543084.

 

Yu H, Zhao G, Li H, et al. Candesartan antagonizes pressure overload-evoked cardiac remodeling through Smad7 gene-dependent MMP-9 suppression. Gene. 2012 Apr 15;497(2):301-6. PMID: 22326534.

 

Yoshioka I, Tsujihata M, Akanae W, et al. Angiotensin type-1 receptor blocker candesartan inhibits calcium oxalate crystal deposition in ethylene glycol-treated rat kidneys. Urology. 2011 Apr;77(4):1007.e9-1007.e14. PMID: 21256551.

 

Wada T, Inada Y, Ojima M, et al. Comparison of the antihypertensive effects of the new angiotensin II (AT1) receptor antagonist candesartan cilexetil (TCV-116) and the angiotensin converting enzyme inhibitor enalapril in rats. Hypertens Res. 1996 Jun;19(2):75-81. Erratum in: Hypertens Res 1996 Sep;19(3):221. PMID: 10968199.

" Xn, Xi Not dangerous goods.

LKT C0260 Capsanthin 50 g 131.7 Carotenoid originally found in Capsicum. Color value:100 (3R,3'S,5'R)-3,3'-dihydroxy-β,κ-caroten-6'one; Paprika extract  465-42-9 Color value:100 584.87 C40H56O3 CC1=C(C(CC(C1)O)(C)C)C=CC(=CC=CC(=CC=CC=C(C)C=CC=C(C)C=CC(=O)C2(CC(CC2(C)C)O)C)C)C Ambient Ambient Insoluble in water.  Soluble in oil. "Zhang X, Zhao WE, Hu L, et al. Carotenoids inhibit proliferation and regulate expression of peroxisome proliferators-activated receptor gamma (PPARγ) in K562 cancer cells. Arch Biochem Biophys. 2011 Aug 1;512(1):96-106. PMID: 21620794.

 

Aizawa K, Inakuma T. Dietary capsanthin, the main carotenoid in paprika (Capsicum annuum), alters plasma high-density lipoprotein-cholesterol levels and hepatic gene expression in rats. Br J Nutr. 2009 Dec;102(12):1760-6. PMID: 19646292.

 

Maoka T, Mochida K, Kozuka M, et al. Cancer chemopreventive activity of carotenoids in the fruits of red paprika Capsicum annuum L. Cancer Lett. 2001 Oct 30;172(2):103-9. PMID: 11566483.

" "Not dangerous goods.

"

LKT C0260 Capsanthin 100 g 206 Carotenoid originally found in Capsicum. Color value:100 (3R,3'S,5'R)-3,3'-dihydroxy-β,κ-caroten-6'one; Paprika extract  465-42-9 Color value:100 584.87 C40H56O3 CC1=C(C(CC(C1)O)(C)C)C=CC(=CC=CC(=CC=CC=C(C)C=CC=C(C)C=CC(=O)C2(CC(CC2(C)C)O)C)C)C Ambient Ambient Insoluble in water.  Soluble in oil. "Zhang X, Zhao WE, Hu L, et al. Carotenoids inhibit proliferation and regulate expression of peroxisome proliferators-activated receptor gamma (PPARγ) in K562 cancer cells. Arch Biochem Biophys. 2011 Aug 1;512(1):96-106. PMID: 21620794.

 

Aizawa K, Inakuma T. Dietary capsanthin, the main carotenoid in paprika (Capsicum annuum), alters plasma high-density lipoprotein-cholesterol levels and hepatic gene expression in rats. Br J Nutr. 2009 Dec;102(12):1760-6. PMID: 19646292.

 

Maoka T, Mochida K, Kozuka M, et al. Cancer chemopreventive activity of carotenoids in the fruits of red paprika Capsicum annuum L. Cancer Lett. 2001 Oct 30;172(2):103-9. PMID: 11566483.

" "Not dangerous goods.

"

LKT W5726 Wogonin 5 mg 121.9 Flavonoid found in Scutellaria; CDK9 inhibitor. 5,7-Dihydroxy-8-methoxyflavone 632-85-9 ≥98% 284.26 C16H12O5 COC1=C(C=C(C2=C1OC(=CC2=O)C3=CC=CC=C3)O)O Ambient -20°C ≥20 mg/ml in DMSO.  1 mg/ml in ethanol.  Insoluble in water. "Chen XM, Bai Y, Zhong YJ, et al. Wogonin has multiple anti-cancer effects by regulating c-Myc/SKP2/Fbw7α and HDAC1/HDAC2 pathways and inducing apoptosis in human lung adenocarcinoma cell line A549. PLoS One. 2013 Nov 12;8(11):e79201. PMID: 24265759.

 

Wang H, Zhao L, Zhu LT, et al. Wogonin reverses hypoxia resistance of human colon cancer HCT116 cells via downregulation of HIF-1α and glycolysis, by inhibiting PI3K/Akt signaling pathway. Mol Carcinog. 2013 Jun 13. [Epub ahead of print]. PMID: 23761018.

 

Polier G, Ding J, Konkimalla BV, et al. Wogonin and related natural flavones are inhibitors of CDK9 that induce apoptosis in cancer cells by transcriptional suppression of Mcl-1. Cell Death Dis. 2011 Jul 21;2:e182. PMID: 21776020

 

Lu N, Gao Y, Ling Y, et al. Wogonin suppresses tumor growth in vivo and VEGF-induced angiogenesis through inhibiting tyrosine phosphorylation of VEGFR2. Life Sci. 2008 Apr 23;82(17-18):956-63. PMID: 18378261.

 

Wakabayashi I. Inhibitory effects of baicalein and wogonin on lipopolysaccharide-induced nitric oxide production in macrophages. Pharmacol Toxicol. 1999 Jun;84(6):288-91. PMID: 10401731.

" None Not dangerous goods.

LKT W5726 Wogonin 10 mg 183.9 Flavonoid found in Scutellaria; CDK9 inhibitor. 5,7-Dihydroxy-8-methoxyflavone 632-85-9 ≥98% 284.26 C16H12O5 COC1=C(C=C(C2=C1OC(=CC2=O)C3=CC=CC=C3)O)O Ambient -20°C ≥20 mg/ml in DMSO.  1 mg/ml in ethanol.  Insoluble in water. "Chen XM, Bai Y, Zhong YJ, et al. Wogonin has multiple anti-cancer effects by regulating c-Myc/SKP2/Fbw7α and HDAC1/HDAC2 pathways and inducing apoptosis in human lung adenocarcinoma cell line A549. PLoS One. 2013 Nov 12;8(11):e79201. PMID: 24265759.

 

Wang H, Zhao L, Zhu LT, et al. Wogonin reverses hypoxia resistance of human colon cancer HCT116 cells via downregulation of HIF-1α and glycolysis, by inhibiting PI3K/Akt signaling pathway. Mol Carcinog. 2013 Jun 13. [Epub ahead of print]. PMID: 23761018.

 

Polier G, Ding J, Konkimalla BV, et al. Wogonin and related natural flavones are inhibitors of CDK9 that induce apoptosis in cancer cells by transcriptional suppression of Mcl-1. Cell Death Dis. 2011 Jul 21;2:e182. PMID: 21776020

 

Lu N, Gao Y, Ling Y, et al. Wogonin suppresses tumor growth in vivo and VEGF-induced angiogenesis through inhibiting tyrosine phosphorylation of VEGFR2. Life Sci. 2008 Apr 23;82(17-18):956-63. PMID: 18378261.

 

Wakabayashi I. Inhibitory effects of baicalein and wogonin on lipopolysaccharide-induced nitric oxide production in macrophages. Pharmacol Toxicol. 1999 Jun;84(6):288-91. PMID: 10401731.

" None Not dangerous goods.

LKT W5726 Wogonin 25 mg 412.5 Flavonoid found in Scutellaria; CDK9 inhibitor. 5,7-Dihydroxy-8-methoxyflavone 632-85-9 ≥98% 284.26 C16H12O5 COC1=C(C=C(C2=C1OC(=CC2=O)C3=CC=CC=C3)O)O Ambient -20°C ≥20 mg/ml in DMSO.  1 mg/ml in ethanol.  Insoluble in water. "Chen XM, Bai Y, Zhong YJ, et al. Wogonin has multiple anti-cancer effects by regulating c-Myc/SKP2/Fbw7α and HDAC1/HDAC2 pathways and inducing apoptosis in human lung adenocarcinoma cell line A549. PLoS One. 2013 Nov 12;8(11):e79201. PMID: 24265759.

 

Wang H, Zhao L, Zhu LT, et al. Wogonin reverses hypoxia resistance of human colon cancer HCT116 cells via downregulation of HIF-1α and glycolysis, by inhibiting PI3K/Akt signaling pathway. Mol Carcinog. 2013 Jun 13. [Epub ahead of print]. PMID: 23761018.

 

Polier G, Ding J, Konkimalla BV, et al. Wogonin and related natural flavones are inhibitors of CDK9 that induce apoptosis in cancer cells by transcriptional suppression of Mcl-1. Cell Death Dis. 2011 Jul 21;2:e182. PMID: 21776020

 

Lu N, Gao Y, Ling Y, et al. Wogonin suppresses tumor growth in vivo and VEGF-induced angiogenesis through inhibiting tyrosine phosphorylation of VEGFR2. Life Sci. 2008 Apr 23;82(17-18):956-63. PMID: 18378261.

 

Wakabayashi I. Inhibitory effects of baicalein and wogonin on lipopolysaccharide-induced nitric oxide production in macrophages. Pharmacol Toxicol. 1999 Jun;84(6):288-91. PMID: 10401731.

" None Not dangerous goods.

LKT C0261 Captopril 1 g 40.7 ACE inhibitor. N-[(S)-3-Mercapto-2-methylpropionyl]-L-proline (2S)-1-(3-Mercapto-2-methylpropionyl)-L-proline; Aceplus; Hypertil;Tensoprel 62571-86-2 ≥81% 217.29 C9H15NO3S CC(CS)C(=O)N1CCCC1C(=O)O Ambient Ambient Soluble in water or ethanol. "Zidane F, Zeder-Lutz G, Altschuh D, et al. Surface plasmon resonance analysis of the binding mechanism of pharmacological and peptidic inhibitors to human somatic angiotensin I-converting enzyme. Biochemistry. 2013 Dec 3;52(48):8722-31. PMID: 24168709.

 

Attoub S, Gaben AM, Al-Salam S, et al. Captopril as a potential inhibitor of lung tumor growth and metastasis. Ann N Y Acad Sci. 2008 Sep;1138:65-72. PMID: 18837885.

" Xn Not dangerous goods.

LKT C0261 Captopril 5 g 108.8 ACE inhibitor. N-[(S)-3-Mercapto-2-methylpropionyl]-L-proline (2S)-1-(3-Mercapto-2-methylpropionyl)-L-proline; Aceplus; Hypertil;Tensoprel 62571-86-2 ≥81% 217.29 C9H15NO3S CC(CS)C(=O)N1CCCC1C(=O)O Ambient Ambient Soluble in water or ethanol. "Zidane F, Zeder-Lutz G, Altschuh D, et al. Surface plasmon resonance analysis of the binding mechanism of pharmacological and peptidic inhibitors to human somatic angiotensin I-converting enzyme. Biochemistry. 2013 Dec 3;52(48):8722-31. PMID: 24168709.

 

Attoub S, Gaben AM, Al-Salam S, et al. Captopril as a potential inhibitor of lung tumor growth and metastasis. Ann N Y Acad Sci. 2008 Sep;1138:65-72. PMID: 18837885.

" Xn Not dangerous goods.

LKT C0261 Captopril 25 g 407.7 ACE inhibitor. N-[(S)-3-Mercapto-2-methylpropionyl]-L-proline (2S)-1-(3-Mercapto-2-methylpropionyl)-L-proline; Aceplus; Hypertil;Tensoprel 62571-86-2 ≥81% 217.29 C9H15NO3S CC(CS)C(=O)N1CCCC1C(=O)O Ambient Ambient Soluble in water or ethanol. "Zidane F, Zeder-Lutz G, Altschuh D, et al. Surface plasmon resonance analysis of the binding mechanism of pharmacological and peptidic inhibitors to human somatic angiotensin I-converting enzyme. Biochemistry. 2013 Dec 3;52(48):8722-31. PMID: 24168709.

 

Attoub S, Gaben AM, Al-Salam S, et al. Captopril as a potential inhibitor of lung tumor growth and metastasis. Ann N Y Acad Sci. 2008 Sep;1138:65-72. PMID: 18837885.

" Xn Not dangerous goods.

LKT W4096 WKYMVM-NH2 0.5 mg 83.9 Synthetic peptide; FPRL1 agonist. WKYMVm; W peptide ≥95% 856.13 C41H61N9O7S2 Ambient -20°C "Kim SD, Kwon S, Lee SK, et al. The immune-stimulating peptide WKYMVm has therapeutic effects against ulcerative colitis. Exp Mol Med. 2013 Sep 13;45:e40. PMID: 24030327.

 

Kim SD, Kim YK, Lee HY, et al. The agonists of formyl peptide receptors prevent development of severe sepsis after microbial infection. J Immunol. 2010 Oct 1;185(7):4302-10. PMID: 20817875.

 

Kwan DH, Kam AY, Wong YH. Activation of the human FPRL-1 receptor promotes Ca2+ mobilization in U87 astrocytoma cells. Neurochem Res. 2008 Jan;33(1):125-33. PMID: 17703360.

 

Kim H, Park JH, Lee EH, et al. Granulocyte function is stimulated by a novel hexapeptide, WKYMVm, in chemotherapy-treated cancer patients. Exp Hematol. 2006 Apr;34(4):407-13. PMID: 16569587.

 

Lee HY, Kang HK, Jo EJ, et al. Trp-Lys-Tyr-Met-Val-Met stimulates phagocytosis via phospho-lipase D-dependent signaling in mouse dendritic cells. Exp Mol Med. 2004 Apr 30;36(2):135-44. PMID: 15150442.

" Not dangerous goods.

LKT W4096 WKYMVM-NH2 1 mg 140.9 Synthetic peptide; FPRL1 agonist. WKYMVm; W peptide ≥95% 856.13 C41H61N9O7S2 Ambient -20°C "Kim SD, Kwon S, Lee SK, et al. The immune-stimulating peptide WKYMVm has therapeutic effects against ulcerative colitis. Exp Mol Med. 2013 Sep 13;45:e40. PMID: 24030327.

 

Kim SD, Kim YK, Lee HY, et al. The agonists of formyl peptide receptors prevent development of severe sepsis after microbial infection. J Immunol. 2010 Oct 1;185(7):4302-10. PMID: 20817875.

 

Kwan DH, Kam AY, Wong YH. Activation of the human FPRL-1 receptor promotes Ca2+ mobilization in U87 astrocytoma cells. Neurochem Res. 2008 Jan;33(1):125-33. PMID: 17703360.

 

Kim H, Park JH, Lee EH, et al. Granulocyte function is stimulated by a novel hexapeptide, WKYMVm, in chemotherapy-treated cancer patients. Exp Hematol. 2006 Apr;34(4):407-13. PMID: 16569587.

 

Lee HY, Kang HK, Jo EJ, et al. Trp-Lys-Tyr-Met-Val-Met stimulates phagocytosis via phospho-lipase D-dependent signaling in mouse dendritic cells. Exp Mol Med. 2004 Apr 30;36(2):135-44. PMID: 15150442.

" Not dangerous goods.

LKT W4096 WKYMVM-NH2 2.5 mg 252.1 Synthetic peptide; FPRL1 agonist. WKYMVm; W peptide ≥95% 856.13 C41H61N9O7S2 Ambient -20°C "Kim SD, Kwon S, Lee SK, et al. The immune-stimulating peptide WKYMVm has therapeutic effects against ulcerative colitis. Exp Mol Med. 2013 Sep 13;45:e40. PMID: 24030327.

 

Kim SD, Kim YK, Lee HY, et al. The agonists of formyl peptide receptors prevent development of severe sepsis after microbial infection. J Immunol. 2010 Oct 1;185(7):4302-10. PMID: 20817875.

 

Kwan DH, Kam AY, Wong YH. Activation of the human FPRL-1 receptor promotes Ca2+ mobilization in U87 astrocytoma cells. Neurochem Res. 2008 Jan;33(1):125-33. PMID: 17703360.

 

Kim H, Park JH, Lee EH, et al. Granulocyte function is stimulated by a novel hexapeptide, WKYMVm, in chemotherapy-treated cancer patients. Exp Hematol. 2006 Apr;34(4):407-13. PMID: 16569587.

 

Lee HY, Kang HK, Jo EJ, et al. Trp-Lys-Tyr-Met-Val-Met stimulates phagocytosis via phospho-lipase D-dependent signaling in mouse dendritic cells. Exp Mol Med. 2004 Apr 30;36(2):135-44. PMID: 15150442.

" Not dangerous goods.

LKT C0262 L-Carnitine 1 g 22.3 Endogenous quaternary ammonium, required for fatty acid transport. 3-Carboxy-2-hydroxy-N,N,N-trimethyl-1-prop- anaminium inner salt Levocarnitine; Vitamin BT; Carnicor; Carnum; Micor; Vitacarn 541-15-1 ≥98% 161.2 C7H15NO3 C[N+](C)(C)CC(CC(=O)[O-])O Very hygroscopic. Ambient Ambient Soluble in water and hot alcohol. "DiNicolantonio JJ, Lavie CJ, Fares H, et al. L-carnitine in the secondary prevention of cardiovascular disease: systematic review and meta-analysis. Mayo Clin Proc. 2013 Jun;88(6):544-51. PMID: 23597877.

 

Wall BT, Stephens FB, Constantin-Teodosiu D, et al. Chronic oral ingestion of L-carnitine and carbohydrate increases muscle carnitine content and alters muscle fuel metabolism during exercise in humans. J Physiol. 2011 Feb 15;589(Pt 4):963-73. PMID: 21224234.

 

Volek JS, Judelson DA, Silvestre R, et al. Effects of carnitine supplementation on flow-mediated dilation and vascular inflammatory responses to a high-fat meal in healthy young adults. Am J Cardiol. 2008 Nov 15;102(10):1413-7. PMID: 18993165.

 

Hooshmand S, Balakrishnan A, Clark RM, et al. Dietary l-carnitine supplementation improves bone mineral density by suppressing bone turnover in aged ovariectomized rats. Phytomedicine. 2008 Aug;15(8):595-601. PMID: 18539446.

 

Volek JS, Kraemer WJ, Rubin MR, et al. L-Carnitine L-tartrate supplementation favorably affects markers of recovery from exercise stress. Am J Physiol Endocrinol Metab. 2002 Feb;282(2):E474-82. PMID: 11788381.

" Xi Not dangerous goods.       

LKT C0262 L-Carnitine 5 g 57.8 Endogenous quaternary ammonium, required for fatty acid transport. 3-Carboxy-2-hydroxy-N,N,N-trimethyl-1-prop- anaminium inner salt Levocarnitine; Vitamin BT; Carnicor; Carnum; Micor; Vitacarn 541-15-1 ≥98% 161.2 C7H15NO3 C[N+](C)(C)CC(CC(=O)[O-])O Very hygroscopic. Ambient Ambient Soluble in water and hot alcohol. "DiNicolantonio JJ, Lavie CJ, Fares H, et al. L-carnitine in the secondary prevention of cardiovascular disease: systematic review and meta-analysis. Mayo Clin Proc. 2013 Jun;88(6):544-51. PMID: 23597877.

 

Wall BT, Stephens FB, Constantin-Teodosiu D, et al. Chronic oral ingestion of L-carnitine and carbohydrate increases muscle carnitine content and alters muscle fuel metabolism during exercise in humans. J Physiol. 2011 Feb 15;589(Pt 4):963-73. PMID: 21224234.

 

Volek JS, Judelson DA, Silvestre R, et al. Effects of carnitine supplementation on flow-mediated dilation and vascular inflammatory responses to a high-fat meal in healthy young adults. Am J Cardiol. 2008 Nov 15;102(10):1413-7. PMID: 18993165.

 

Hooshmand S, Balakrishnan A, Clark RM, et al. Dietary l-carnitine supplementation improves bone mineral density by suppressing bone turnover in aged ovariectomized rats. Phytomedicine. 2008 Aug;15(8):595-601. PMID: 18539446.

 

Volek JS, Kraemer WJ, Rubin MR, et al. L-Carnitine L-tartrate supplementation favorably affects markers of recovery from exercise stress. Am J Physiol Endocrinol Metab. 2002 Feb;282(2):E474-82. PMID: 11788381.

" Xi Not dangerous goods.       

LKT C0262 L-Carnitine 25 g 231.1 Endogenous quaternary ammonium, required for fatty acid transport. 3-Carboxy-2-hydroxy-N,N,N-trimethyl-1-prop- anaminium inner salt Levocarnitine; Vitamin BT; Carnicor; Carnum; Micor; Vitacarn 541-15-1 ≥98% 161.2 C7H15NO3 C[N+](C)(C)CC(CC(=O)[O-])O Very hygroscopic. Ambient Ambient Soluble in water and hot alcohol. "DiNicolantonio JJ, Lavie CJ, Fares H, et al. L-carnitine in the secondary prevention of cardiovascular disease: systematic review and meta-analysis. Mayo Clin Proc. 2013 Jun;88(6):544-51. PMID: 23597877.

 

Wall BT, Stephens FB, Constantin-Teodosiu D, et al. Chronic oral ingestion of L-carnitine and carbohydrate increases muscle carnitine content and alters muscle fuel metabolism during exercise in humans. J Physiol. 2011 Feb 15;589(Pt 4):963-73. PMID: 21224234.

 

Volek JS, Judelson DA, Silvestre R, et al. Effects of carnitine supplementation on flow-mediated dilation and vascular inflammatory responses to a high-fat meal in healthy young adults. Am J Cardiol. 2008 Nov 15;102(10):1413-7. PMID: 18993165.

 

Hooshmand S, Balakrishnan A, Clark RM, et al. Dietary l-carnitine supplementation improves bone mineral density by suppressing bone turnover in aged ovariectomized rats. Phytomedicine. 2008 Aug;15(8):595-601. PMID: 18539446.

 

Volek JS, Kraemer WJ, Rubin MR, et al. L-Carnitine L-tartrate supplementation favorably affects markers of recovery from exercise stress. Am J Physiol Endocrinol Metab. 2002 Feb;282(2):E474-82. PMID: 11788381.

" Xi Not dangerous goods.       

LKT W3576 Withaferin A 1 mg 131.4 Steroid lactone produced by Withania somnifera; vimentin and HSP90 inhibitor. 5119-48-2 ≥98% 470.6 C28H38O6 CC1=C(C(=O)OC(C1)C(C)C2CCC3C2(CCC4C3CC5C6(C4(C(=O)C=CC6O)C)O5)C)CO Ambient 4°C Methanol, Ethanol, DMSO "Antony ML, Lee J, Hahm ER, et al. Growth Arrest by the Antitumor Steroidal Lactone Withaferin A in Human Breast Cancer Cells Is Associated with Downregulation and Covalent Binding at Cysteine-303 of β-Tubulin. J Biol Chem. 2013 Dec 2. [Epub ahead of print]. PMID: 24297176.

 

Hahm ER, Lee J, Singh SV. Role of mitogen-activated protein kinases and Mcl-1 in apoptosis induction by withaferin A in human breast cancer cells. Mol Carcinog. 2013 Sep 9. [Epub ahead of print]. PMID: 24019090.

 

Lee J, Sehrawat A, Singh SV. Withaferin A causes activation of Notch2 and Notch4 in human breast cancer cells. Breast Cancer Res Treat. 2012 Nov;136(1):45-56. PMID: 22965833.

 

Zhang X, Samadi AK, Roby KF, et al. Inhibition of cell growth and induction of apoptosis in ovarian carcinoma cell lines CaOV3 and SKOV3 by natural withanolide Withaferin A. Gynecol Oncol. 2012 Mar;124(3):606-12. PMID: 22188785.

 

Hahm ER, Lee J, Huang Y, et al. Withaferin a suppresses estrogen receptor-α expression in human breast cancer cells. Mol Carcinog. 2011 Aug;50(8):614-24. PMID: 21432907.

 

Yu Y, Hamza A, Zhang T, et al. Withaferin A targets heat shock protein 90 in pancreatic cancer cells. Biochem Pharmacol. 2010 Feb 15;79(4):542-51. PMID: 19769945.

 

Oh JH, Lee TJ, Park JW, et al. Withaferin A inhibits iNOS expression and nitric oxide production by Akt inactivation and down-regulating LPS-induced activity of NF-kappaB in RAW 264.7 cells. Eur J Pharmacol. 2008 Dec 3;599(1-3):11-7. PMID: 18838070.

" Not dangerous goods.

LKT W3576 Withaferin A 5 mg 562.5 Steroid lactone produced by Withania somnifera; vimentin and HSP90 inhibitor. 5119-48-2 ≥98% 470.6 C28H38O6 CC1=C(C(=O)OC(C1)C(C)C2CCC3C2(CCC4C3CC5C6(C4(C(=O)C=CC6O)C)O5)C)CO Ambient 4°C Methanol, Ethanol, DMSO "Antony ML, Lee J, Hahm ER, et al. Growth Arrest by the Antitumor Steroidal Lactone Withaferin A in Human Breast Cancer Cells Is Associated with Downregulation and Covalent Binding at Cysteine-303 of β-Tubulin. J Biol Chem. 2013 Dec 2. [Epub ahead of print]. PMID: 24297176.

 

Hahm ER, Lee J, Singh SV. Role of mitogen-activated protein kinases and Mcl-1 in apoptosis induction by withaferin A in human breast cancer cells. Mol Carcinog. 2013 Sep 9. [Epub ahead of print]. PMID: 24019090.

 

Lee J, Sehrawat A, Singh SV. Withaferin A causes activation of Notch2 and Notch4 in human breast cancer cells. Breast Cancer Res Treat. 2012 Nov;136(1):45-56. PMID: 22965833.

 

Zhang X, Samadi AK, Roby KF, et al. Inhibition of cell growth and induction of apoptosis in ovarian carcinoma cell lines CaOV3 and SKOV3 by natural withanolide Withaferin A. Gynecol Oncol. 2012 Mar;124(3):606-12. PMID: 22188785.

 

Hahm ER, Lee J, Huang Y, et al. Withaferin a suppresses estrogen receptor-α expression in human breast cancer cells. Mol Carcinog. 2011 Aug;50(8):614-24. PMID: 21432907.

 

Yu Y, Hamza A, Zhang T, et al. Withaferin A targets heat shock protein 90 in pancreatic cancer cells. Biochem Pharmacol. 2010 Feb 15;79(4):542-51. PMID: 19769945.

 

Oh JH, Lee TJ, Park JW, et al. Withaferin A inhibits iNOS expression and nitric oxide production by Akt inactivation and down-regulating LPS-induced activity of NF-kappaB in RAW 264.7 cells. Eur J Pharmacol. 2008 Dec 3;599(1-3):11-7. PMID: 18838070.

" Not dangerous goods.

LKT C0263 L-Carnitine Hydrochloride 1 g 20.8 Endogenous quaternary ammonium, required for fatty acid transport. 3-Carboxy-2-hydroxy-N,N,N-trimethyl-1-prop- anaminium inner salt hydrochloride Lefcar; Metina 6645-46-1 ≥98% 197.66 C7H15NO3 HCl C[N+](C)(C)CC(CC(=O)O)O.[Cl-] Ambient Ambient "DiNicolantonio JJ, Lavie CJ, Fares H, et al. L-carnitine in the secondary prevention of cardiovascular disease: systematic review and meta-analysis. Mayo Clin Proc. 2013 Jun;88(6):544-51. PMID: 23597877.

 

Wall BT, Stephens FB, Constantin-Teodosiu D, et al. Chronic oral ingestion of L-carnitine and carbohydrate increases muscle carnitine content and alters muscle fuel metabolism during exercise in humans. J Physiol. 2011 Feb 15;589(Pt 4):963-73. PMID: 21224234.

 

Volek JS, Judelson DA, Silvestre R, et al. Effects of carnitine supplementation on flow-mediated dilation and vascular inflammatory responses to a high-fat meal in healthy young adults. Am J Cardiol. 2008 Nov 15;102(10):1413-7. PMID: 18993165.

 

Hooshmand S, Balakrishnan A, Clark RM, et al. Dietary l-carnitine supplementation improves bone mineral density by suppressing bone turnover in aged ovariectomized rats. Phytomedicine. 2008 Aug;15(8):595-601. PMID: 18539446.

 

Volek JS, Kraemer WJ, Rubin MR, et al. L-Carnitine L-tartrate supplementation favorably affects markers of recovery from exercise stress. Am J Physiol Endocrinol Metab. 2002 Feb;282(2):E474-82. PMID: 11788381.

" Xi Not dangerous goods.

LKT C0263 L-Carnitine Hydrochloride 5 g 53.2 Endogenous quaternary ammonium, required for fatty acid transport. 3-Carboxy-2-hydroxy-N,N,N-trimethyl-1-prop- anaminium inner salt hydrochloride Lefcar; Metina 6645-46-1 ≥98% 197.66 C7H15NO3 HCl C[N+](C)(C)CC(CC(=O)O)O.[Cl-] Ambient Ambient "DiNicolantonio JJ, Lavie CJ, Fares H, et al. L-carnitine in the secondary prevention of cardiovascular disease: systematic review and meta-analysis. Mayo Clin Proc. 2013 Jun;88(6):544-51. PMID: 23597877.

 

Wall BT, Stephens FB, Constantin-Teodosiu D, et al. Chronic oral ingestion of L-carnitine and carbohydrate increases muscle carnitine content and alters muscle fuel metabolism during exercise in humans. J Physiol. 2011 Feb 15;589(Pt 4):963-73. PMID: 21224234.

 

Volek JS, Judelson DA, Silvestre R, et al. Effects of carnitine supplementation on flow-mediated dilation and vascular inflammatory responses to a high-fat meal in healthy young adults. Am J Cardiol. 2008 Nov 15;102(10):1413-7. PMID: 18993165.

 

Hooshmand S, Balakrishnan A, Clark RM, et al. Dietary l-carnitine supplementation improves bone mineral density by suppressing bone turnover in aged ovariectomized rats. Phytomedicine. 2008 Aug;15(8):595-601. PMID: 18539446.

 

Volek JS, Kraemer WJ, Rubin MR, et al. L-Carnitine L-tartrate supplementation favorably affects markers of recovery from exercise stress. Am J Physiol Endocrinol Metab. 2002 Feb;282(2):E474-82. PMID: 11788381.

" Xi Not dangerous goods.

LKT C0263 L-Carnitine Hydrochloride 25 g 208 Endogenous quaternary ammonium, required for fatty acid transport. 3-Carboxy-2-hydroxy-N,N,N-trimethyl-1-prop- anaminium inner salt hydrochloride Lefcar; Metina 6645-46-1 ≥98% 197.66 C7H15NO3 HCl C[N+](C)(C)CC(CC(=O)O)O.[Cl-] Ambient Ambient "DiNicolantonio JJ, Lavie CJ, Fares H, et al. L-carnitine in the secondary prevention of cardiovascular disease: systematic review and meta-analysis. Mayo Clin Proc. 2013 Jun;88(6):544-51. PMID: 23597877.

 

Wall BT, Stephens FB, Constantin-Teodosiu D, et al. Chronic oral ingestion of L-carnitine and carbohydrate increases muscle carnitine content and alters muscle fuel metabolism during exercise in humans. J Physiol. 2011 Feb 15;589(Pt 4):963-73. PMID: 21224234.

 

Volek JS, Judelson DA, Silvestre R, et al. Effects of carnitine supplementation on flow-mediated dilation and vascular inflammatory responses to a high-fat meal in healthy young adults. Am J Cardiol. 2008 Nov 15;102(10):1413-7. PMID: 18993165.

 

Hooshmand S, Balakrishnan A, Clark RM, et al. Dietary l-carnitine supplementation improves bone mineral density by suppressing bone turnover in aged ovariectomized rats. Phytomedicine. 2008 Aug;15(8):595-601. PMID: 18539446.

 

Volek JS, Kraemer WJ, Rubin MR, et al. L-Carnitine L-tartrate supplementation favorably affects markers of recovery from exercise stress. Am J Physiol Endocrinol Metab. 2002 Feb;282(2):E474-82. PMID: 11788381.

" Xi Not dangerous goods.

LKT W0270 (±)-Warfarin Sodium Clathrate 1 g 27.2 Coumarin; VKORC1 inhibitor. 129-06-6 ≥98% 330.31 C19H15NaO4 CC(=O)CC(C1=CC=CC=C1)C2=C(C3=CC=CC=C3OC2=O)[O-].[Na+] Ambient Ambient Very soluble in water, freely soluble in ethanol, soluble in acetone, very slightly soluble in ether. "Hall AM, Wilkins MR. Warfarin: a case history in pharmacogenetics. Heart. 2005 May;91(5):563-4. PMID: 15831631.

 

Tabrizi AR, Zehnbauer BA, Borecki IB, et al. The frequency and effects of cytochrome P450 (CYP) 2C9 polymorphisms in patients receiving warfarin. J Am Coll Surg. 2002 Mar;194(3):267-73. PMID: 11893129.

 

Freedman MD. Oral anticoagulants: pharmacodynamics, clinical indications and adverse effects. J Clin Pharmacol. 1992 Mar;32(3):196-209. PMID:1564123.

 

Wallin R, Martin LF. Vitamin K-dependent carboxylation and vitamin K metabolism in liver. Effects of warfarin. J Clin Invest. 1985 Nov;76(5):1879-84. PMID: 3932474.

 

Suttie JW. Mechanism of action of vitamin K: demonstration of a liver precursor of prothrombin. Science. 1973 Jan 12;179(4069):192-4. PMID: 4682251.

" T+, Repr. "UN number: 1544     Class: 6.1     Packing Group: II

Proper shipping name: Alkaloid salts, solid, n.o.s. (Warfarin sodium)"

LKT W0270 (±)-Warfarin Sodium Clathrate 10 g 77.6 Coumarin; VKORC1 inhibitor. 129-06-6 ≥98% 330.31 C19H15NaO4 CC(=O)CC(C1=CC=CC=C1)C2=C(C3=CC=CC=C3OC2=O)[O-].[Na+] Ambient Ambient Very soluble in water, freely soluble in ethanol, soluble in acetone, very slightly soluble in ether. "Hall AM, Wilkins MR. Warfarin: a case history in pharmacogenetics. Heart. 2005 May;91(5):563-4. PMID: 15831631.

 

Tabrizi AR, Zehnbauer BA, Borecki IB, et al. The frequency and effects of cytochrome P450 (CYP) 2C9 polymorphisms in patients receiving warfarin. J Am Coll Surg. 2002 Mar;194(3):267-73. PMID: 11893129.

 

Freedman MD. Oral anticoagulants: pharmacodynamics, clinical indications and adverse effects. J Clin Pharmacol. 1992 Mar;32(3):196-209. PMID:1564123.

 

Wallin R, Martin LF. Vitamin K-dependent carboxylation and vitamin K metabolism in liver. Effects of warfarin. J Clin Invest. 1985 Nov;76(5):1879-84. PMID: 3932474.

 

Suttie JW. Mechanism of action of vitamin K: demonstration of a liver precursor of prothrombin. Science. 1973 Jan 12;179(4069):192-4. PMID: 4682251.

" T+, Repr. "UN number: 1544     Class: 6.1     Packing Group: II

Proper shipping name: Alkaloid salts, solid, n.o.s. (Warfarin sodium)"

LKT W0270 (±)-Warfarin Sodium Clathrate 25 g 151.7 Coumarin; VKORC1 inhibitor. 129-06-6 ≥98% 330.31 C19H15NaO4 CC(=O)CC(C1=CC=CC=C1)C2=C(C3=CC=CC=C3OC2=O)[O-].[Na+] Ambient Ambient Very soluble in water, freely soluble in ethanol, soluble in acetone, very slightly soluble in ether. "Hall AM, Wilkins MR. Warfarin: a case history in pharmacogenetics. Heart. 2005 May;91(5):563-4. PMID: 15831631.

 

Tabrizi AR, Zehnbauer BA, Borecki IB, et al. The frequency and effects of cytochrome P450 (CYP) 2C9 polymorphisms in patients receiving warfarin. J Am Coll Surg. 2002 Mar;194(3):267-73. PMID: 11893129.

 

Freedman MD. Oral anticoagulants: pharmacodynamics, clinical indications and adverse effects. J Clin Pharmacol. 1992 Mar;32(3):196-209. PMID:1564123.

 

Wallin R, Martin LF. Vitamin K-dependent carboxylation and vitamin K metabolism in liver. Effects of warfarin. J Clin Invest. 1985 Nov;76(5):1879-84. PMID: 3932474.

 

Suttie JW. Mechanism of action of vitamin K: demonstration of a liver precursor of prothrombin. Science. 1973 Jan 12;179(4069):192-4. PMID: 4682251.

" T+, Repr. "UN number: 1544     Class: 6.1     Packing Group: II

Proper shipping name: Alkaloid salts, solid, n.o.s. (Warfarin sodium)"

LKT C0264 L-Carnitine Tartrate 1 g 20.8 Endogenous quaternary ammonium, required for fatty acid transport. 3-Carboxy-2-hydroxy-N,N,N-trimethyl-1-prop- anaminium inner salt tartrate 36687-82-8 ≥98% 472.49 2(C7H15NO3)2 C4H6O6 C[N+](C)(C)CC(CC(=O)[O-])O.C(C(C(=O)O)O)(C(=O)O)O Ambient Ambient Soluble in water. "DiNicolantonio JJ, Lavie CJ, Fares H, et al. L-carnitine in the secondary prevention of cardiovascular disease: systematic review and meta-analysis. Mayo Clin Proc. 2013 Jun;88(6):544-51. PMID: 23597877.

 

Wall BT, Stephens FB, Constantin-Teodosiu D, et al. Chronic oral ingestion of L-carnitine and carbohydrate increases muscle carnitine content and alters muscle fuel metabolism during exercise in humans. J Physiol. 2011 Feb 15;589(Pt 4):963-73. PMID: 21224234.

 

Volek JS, Judelson DA, Silvestre R, et al. Effects of carnitine supplementation on flow-mediated dilation and vascular inflammatory responses to a high-fat meal in healthy young adults. Am J Cardiol. 2008 Nov 15;102(10):1413-7. PMID: 18993165.

 

Hooshmand S, Balakrishnan A, Clark RM, et al. Dietary l-carnitine supplementation improves bone mineral density by suppressing bone turnover in aged ovariectomized rats. Phytomedicine. 2008 Aug;15(8):595-601. PMID: 18539446.

 

Volek JS, Kraemer WJ, Rubin MR, et al. L-Carnitine L-tartrate supplementation favorably affects markers of recovery from exercise stress. Am J Physiol Endocrinol Metab. 2002 Feb;282(2):E474-82. PMID: 11788381.

" Xi Not dangerous goods.

LKT C0264 L-Carnitine Tartrate 5 g 53.2 Endogenous quaternary ammonium, required for fatty acid transport. 3-Carboxy-2-hydroxy-N,N,N-trimethyl-1-prop- anaminium inner salt tartrate 36687-82-8 ≥98% 472.49 2(C7H15NO3)2 C4H6O6 C[N+](C)(C)CC(CC(=O)[O-])O.C(C(C(=O)O)O)(C(=O)O)O Ambient Ambient Soluble in water. "DiNicolantonio JJ, Lavie CJ, Fares H, et al. L-carnitine in the secondary prevention of cardiovascular disease: systematic review and meta-analysis. Mayo Clin Proc. 2013 Jun;88(6):544-51. PMID: 23597877.

 

Wall BT, Stephens FB, Constantin-Teodosiu D, et al. Chronic oral ingestion of L-carnitine and carbohydrate increases muscle carnitine content and alters muscle fuel metabolism during exercise in humans. J Physiol. 2011 Feb 15;589(Pt 4):963-73. PMID: 21224234.

 

Volek JS, Judelson DA, Silvestre R, et al. Effects of carnitine supplementation on flow-mediated dilation and vascular inflammatory responses to a high-fat meal in healthy young adults. Am J Cardiol. 2008 Nov 15;102(10):1413-7. PMID: 18993165.

 

Hooshmand S, Balakrishnan A, Clark RM, et al. Dietary l-carnitine supplementation improves bone mineral density by suppressing bone turnover in aged ovariectomized rats. Phytomedicine. 2008 Aug;15(8):595-601. PMID: 18539446.

 

Volek JS, Kraemer WJ, Rubin MR, et al. L-Carnitine L-tartrate supplementation favorably affects markers of recovery from exercise stress. Am J Physiol Endocrinol Metab. 2002 Feb;282(2):E474-82. PMID: 11788381.

" Xi Not dangerous goods.

LKT C0264 L-Carnitine Tartrate 25 g 208 Endogenous quaternary ammonium, required for fatty acid transport. 3-Carboxy-2-hydroxy-N,N,N-trimethyl-1-prop- anaminium inner salt tartrate 36687-82-8 ≥98% 472.49 2(C7H15NO3)2 C4H6O6 C[N+](C)(C)CC(CC(=O)[O-])O.C(C(C(=O)O)O)(C(=O)O)O Ambient Ambient Soluble in water. "DiNicolantonio JJ, Lavie CJ, Fares H, et al. L-carnitine in the secondary prevention of cardiovascular disease: systematic review and meta-analysis. Mayo Clin Proc. 2013 Jun;88(6):544-51. PMID: 23597877.

 

Wall BT, Stephens FB, Constantin-Teodosiu D, et al. Chronic oral ingestion of L-carnitine and carbohydrate increases muscle carnitine content and alters muscle fuel metabolism during exercise in humans. J Physiol. 2011 Feb 15;589(Pt 4):963-73. PMID: 21224234.

 

Volek JS, Judelson DA, Silvestre R, et al. Effects of carnitine supplementation on flow-mediated dilation and vascular inflammatory responses to a high-fat meal in healthy young adults. Am J Cardiol. 2008 Nov 15;102(10):1413-7. PMID: 18993165.

 

Hooshmand S, Balakrishnan A, Clark RM, et al. Dietary l-carnitine supplementation improves bone mineral density by suppressing bone turnover in aged ovariectomized rats. Phytomedicine. 2008 Aug;15(8):595-601. PMID: 18539446.

 

Volek JS, Kraemer WJ, Rubin MR, et al. L-Carnitine L-tartrate supplementation favorably affects markers of recovery from exercise stress. Am J Physiol Endocrinol Metab. 2002 Feb;282(2):E474-82. PMID: 11788381.

" Xi Not dangerous goods.

LKT C0265 Carnosic Acid 25 mg 122.3 Diterpene found in Rosmarinus. Salvin 3650-09-7 ≥98% 332.43 C20H28O4 CC(C)C1=C(C(=C2C(=C1)CCC3C2(CCCC3(C)C)C(=O)O)O)O Ambient -20°C Slightly soluble in water. soluble in DMSO. "Kim YJ, Kim JS, Seo YR, et al. Carnosic acid suppresses colon tumor formation in association with anti-adipogenic activity. Mol Nutr Food Res. 2014 Sep 9. [Epub ahead of print]. PMID: 25204550.

 

Gao Q, Liu H, Yao Y, et al. Carnosic acid induces autophagic cell death through inhibition of the Akt/mTOR pathway in human hepatoma cells. J Appl Toxicol. 2014 Sep 1. [Epub ahead of print]. PMID: 25178877.

 

Sahu BD, Putcha UK, Kuncha M, et al. Carnosic acid promotes myocardial antioxidant response and prevents isoproterenol-induced myocardial oxidative stress and apoptosis in mice. Mol Cell Biochem. 2014 Sep;394(1-2):163-76. PMID: 24903830.

 

Tsai CW, Liu KL, Lin YR, et al. The mechanisms of carnosic acid attenuates tumor necrosis factor-α-mediated inflammation and insulin resistance in 3T3-L1 adipocytes. Mol Nutr Food Res. 2014 Apr;58(4):654-64. PMID: 24668853.

 

Rasoolijazi H, Azad N, Joghataei MT, et al. The protective role of carnosic acid against beta-amyloid toxicity in rats. ScientificWorldJournal. 2013 Oct 24;2013:917082. PMID: 24363627.

" Not dangerous goods.

LKT C0265 Carnosic Acid 50 mg 206.5 Diterpene found in Rosmarinus. Salvin 3650-09-7 ≥98% 332.43 C20H28O4 CC(C)C1=C(C(=C2C(=C1)CCC3C2(CCCC3(C)C)C(=O)O)O)O Ambient -20°C Slightly soluble in water. soluble in DMSO. "Kim YJ, Kim JS, Seo YR, et al. Carnosic acid suppresses colon tumor formation in association with anti-adipogenic activity. Mol Nutr Food Res. 2014 Sep 9. [Epub ahead of print]. PMID: 25204550.

 

Gao Q, Liu H, Yao Y, et al. Carnosic acid induces autophagic cell death through inhibition of the Akt/mTOR pathway in human hepatoma cells. J Appl Toxicol. 2014 Sep 1. [Epub ahead of print]. PMID: 25178877.

 

Sahu BD, Putcha UK, Kuncha M, et al. Carnosic acid promotes myocardial antioxidant response and prevents isoproterenol-induced myocardial oxidative stress and apoptosis in mice. Mol Cell Biochem. 2014 Sep;394(1-2):163-76. PMID: 24903830.

 

Tsai CW, Liu KL, Lin YR, et al. The mechanisms of carnosic acid attenuates tumor necrosis factor-α-mediated inflammation and insulin resistance in 3T3-L1 adipocytes. Mol Nutr Food Res. 2014 Apr;58(4):654-64. PMID: 24668853.

 

Rasoolijazi H, Azad N, Joghataei MT, et al. The protective role of carnosic acid against beta-amyloid toxicity in rats. ScientificWorldJournal. 2013 Oct 24;2013:917082. PMID: 24363627.

" Not dangerous goods.

LKT C0266 Capsaicin, natural 100 mg 40.7 Found in Capsicum; TRPV agonist. (6E)-N-[(4-Hydroxy-3-methoxyphenyl)methyl]-8- methyl-6-nonenamide Axsain; Mioton; Zacin; Zostrix 404-86-4 ≥95% 305.41 C18H27NO3 CC(C)C=CCCCCC(=O)NCC1=CC(=C(C=C1)O)OC Ambient 4°C Soluble in ether, benzene, and chloroform. Practically insoluble in cold water. "Díaz-Laviada I, Rodríguez-Henche N. The potential antitumor effects of capsaicin. Prog Drug Res. 2014;68:181-208. PMID: 24941670.

 

Leung FW. Capsaicin as an anti-obesity drug. Prog Drug Res. 2014;68:171-9. PMID: 24941669.

 

Kissin I. Vanilloid-induced conduction analgesia: selective, dose-dependent, long-lasting, with a low level of potential neurotoxicity. Anesth Analg. 2008 Jul;107(1):271-81. PMID: 18635498.

 

Jensen PG, Curtis PD, Dunn JA, et al. Field evaluation of capsaicin as a rodent aversion agent for poultry feed. Pest Manag Sci. 2003 Sep;59(9):1007-15. PMID: 12974352.

" T "UN number: 2811     Class:  6.1     Packing group:  III

Proper shipping name:  Toxic solids, organic, n.o.s. (Capsaicin)

Marine pollutant:  No     Poison Inhalation Hazard:  No"

LKT C0266 Capsaicin, natural 250 mg 57.1 Found in Capsicum; TRPV agonist. (6E)-N-[(4-Hydroxy-3-methoxyphenyl)methyl]-8- methyl-6-nonenamide Axsain; Mioton; Zacin; Zostrix 404-86-4 ≥95% 305.41 C18H27NO3 CC(C)C=CCCCCC(=O)NCC1=CC(=C(C=C1)O)OC Ambient 4°C Soluble in ether, benzene, and chloroform. Practically insoluble in cold water. "Díaz-Laviada I, Rodríguez-Henche N. The potential antitumor effects of capsaicin. Prog Drug Res. 2014;68:181-208. PMID: 24941670.

 

Leung FW. Capsaicin as an anti-obesity drug. Prog Drug Res. 2014;68:171-9. PMID: 24941669.

 

Kissin I. Vanilloid-induced conduction analgesia: selective, dose-dependent, long-lasting, with a low level of potential neurotoxicity. Anesth Analg. 2008 Jul;107(1):271-81. PMID: 18635498.

 

Jensen PG, Curtis PD, Dunn JA, et al. Field evaluation of capsaicin as a rodent aversion agent for poultry feed. Pest Manag Sci. 2003 Sep;59(9):1007-15. PMID: 12974352.

" T "UN number: 2811     Class:  6.1     Packing group:  III

Proper shipping name:  Toxic solids, organic, n.o.s. (Capsaicin)

Marine pollutant:  No     Poison Inhalation Hazard:  No"

LKT C0266 Capsaicin, natural 1 g 169.9 Found in Capsicum; TRPV agonist. (6E)-N-[(4-Hydroxy-3-methoxyphenyl)methyl]-8- methyl-6-nonenamide Axsain; Mioton; Zacin; Zostrix 404-86-4 ≥95% 305.41 C18H27NO3 CC(C)C=CCCCCC(=O)NCC1=CC(=C(C=C1)O)OC Ambient 4°C Soluble in ether, benzene, and chloroform. Practically insoluble in cold water. "Díaz-Laviada I, Rodríguez-Henche N. The potential antitumor effects of capsaicin. Prog Drug Res. 2014;68:181-208. PMID: 24941670.

 

Leung FW. Capsaicin as an anti-obesity drug. Prog Drug Res. 2014;68:171-9. PMID: 24941669.

 

Kissin I. Vanilloid-induced conduction analgesia: selective, dose-dependent, long-lasting, with a low level of potential neurotoxicity. Anesth Analg. 2008 Jul;107(1):271-81. PMID: 18635498.

 

Jensen PG, Curtis PD, Dunn JA, et al. Field evaluation of capsaicin as a rodent aversion agent for poultry feed. Pest Manag Sci. 2003 Sep;59(9):1007-15. PMID: 12974352.

" T "UN number: 2811     Class:  6.1     Packing group:  III

Proper shipping name:  Toxic solids, organic, n.o.s. (Capsaicin)

Marine pollutant:  No     Poison Inhalation Hazard:  No"

LKT C0267 Carnosol 1 mg 47.6 Diterpene compound originally found in Rosmarinus; PGE2 synthase inhibitor. "2H-9,4a-(Epoxymethano)phenanthren-12-one,1,3,4,9,110a-hexahydro-5,6-dihydroxy-1,1-dimethyl-7-(1- methylethyl)-, (4aR-(4aalpha,9alpha,10abeta))- 

" CCRIS 7122 5957-80-2 ≥98% 330.42 C20H26O4 CC(C)C1=C(C(=C2C(=C1)C3CC4C2(CCCC4(C)C)C(=O)O3)O)O Protect from light. Blue Ice -20°C Soluble in DMSO, DMF or ethanol. Sparingly soluble in aqueaous buffers. "Vergara D, Simeone P, Bettini S, et al. Antitumor activity of the dietary diterpene carnosol against a panel of human cancer cell lines. Food Funct. 2014 Jun 28;5(6):1261-9. PMID: 24733049.

 

Park KW, Kundu J, Chae IG, et al. Carnosol induces apoptosis through generation of ROS and inactivation of STAT3 signaling in human colon cancer HCT116 cells. Int J Oncol. 2014 Apr;44(4):1309-15. PMID: 24481553.

 

López-Jiménez A, García-Caballero M, Medina MÁ, et al. Anti-angiogenic properties of carnosol and carnosic acid, two major dietary compounds from rosemary. Eur J Nutr. 2013 Feb;52(1):85-95. PMID: 22173778.

 

Machado DG, Cunha MP, Neis VB, et al. Antidepressant-like effects of fractions, essential oil, carnosol and betulinic acid isolated from Rosmarinus officinalis L. Food Chem. 2013 Jan 15;136(2):999-1005. PMID: 23122155.

 

Bauer J, Kuehnl S, Rollinger JM, et al. Carnosol and carnosic acids from Salvia officinalis inhibit microsomal prostaglandin E2 synthase-1. J Pharmacol Exp Ther. 2012 Jul;342(1):169-76. PMID: 22511203.

 

Mengoni ES, Vichera G, Rigano LA, et al. Suppression of COX-2, IL-1β and TNF-α expression and leukocyte infiltration in inflamed skin by bioactive compounds from Rosmarinus officinalis L. Fitoterapia. 2011 Apr;82(3):414-21. PMID: 21129455.

 

Johnson JJ, Syed DN, Suh Y, et al. Disruption of androgen and estrogen receptor activity in prostate cancer by a novel dietary diterpene carnosol: implications for chemoprevention. Cancer Prev Res (Phila). 2010 Sep;3(9):1112-23. PMID: 20736335.

" U/A Not dangerous goods.

LKT C0267 Carnosol 5 mg 217.4 Diterpene compound originally found in Rosmarinus; PGE2 synthase inhibitor. "2H-9,4a-(Epoxymethano)phenanthren-12-one,1,3,4,9,110a-hexahydro-5,6-dihydroxy-1,1-dimethyl-7-(1- methylethyl)-, (4aR-(4aalpha,9alpha,10abeta))- 

" CCRIS 7122 5957-80-2 ≥98% 330.42 C20H26O4 CC(C)C1=C(C(=C2C(=C1)C3CC4C2(CCCC4(C)C)C(=O)O3)O)O Protect from light. Blue Ice -20°C Soluble in DMSO, DMF or ethanol. Sparingly soluble in aqueaous buffers. "Vergara D, Simeone P, Bettini S, et al. Antitumor activity of the dietary diterpene carnosol against a panel of human cancer cell lines. Food Funct. 2014 Jun 28;5(6):1261-9. PMID: 24733049.

 

Park KW, Kundu J, Chae IG, et al. Carnosol induces apoptosis through generation of ROS and inactivation of STAT3 signaling in human colon cancer HCT116 cells. Int J Oncol. 2014 Apr;44(4):1309-15. PMID: 24481553.

 

López-Jiménez A, García-Caballero M, Medina MÁ, et al. Anti-angiogenic properties of carnosol and carnosic acid, two major dietary compounds from rosemary. Eur J Nutr. 2013 Feb;52(1):85-95. PMID: 22173778.

 

Machado DG, Cunha MP, Neis VB, et al. Antidepressant-like effects of fractions, essential oil, carnosol and betulinic acid isolated from Rosmarinus officinalis L. Food Chem. 2013 Jan 15;136(2):999-1005. PMID: 23122155.

 

Bauer J, Kuehnl S, Rollinger JM, et al. Carnosol and carnosic acids from Salvia officinalis inhibit microsomal prostaglandin E2 synthase-1. J Pharmacol Exp Ther. 2012 Jul;342(1):169-76. PMID: 22511203.

 

Mengoni ES, Vichera G, Rigano LA, et al. Suppression of COX-2, IL-1β and TNF-α expression and leukocyte infiltration in inflamed skin by bioactive compounds from Rosmarinus officinalis L. Fitoterapia. 2011 Apr;82(3):414-21. PMID: 21129455.

 

Johnson JJ, Syed DN, Suh Y, et al. Disruption of androgen and estrogen receptor activity in prostate cancer by a novel dietary diterpene carnosol: implications for chemoprevention. Cancer Prev Res (Phila). 2010 Sep;3(9):1112-23. PMID: 20736335.

" U/A Not dangerous goods.

LKT V5886 Voriconazole 100 mg 125.6 Triazole; 14α demethylase inhibitor. (2R,3S)-2-(2,4-difluorophenyl)-3-(5-fluoropyrimidin-4-yl)-1-(1,2,4-triazol-1-yl)butan-2-ol 137234-62-9 ≥98% 349.31 C16H14F3N5O CC(C1=NC=NC=C1F)C(CN2C=NC=N2)(C3=C(C=C(C=C3)F)F)O Ambient Ambient "Thompson GR 3rd, Lewis JS 2nd. Pharmacology and clinical use of voriconazole. Expert Opin Drug Metab Toxicol. 2010 Jan;6(1):83-94. PMID: 19947892.

 

Simitsopoulou M, Roilides E, Paliogianni F, et al. Immunomodulatory effects of voriconazole on monocytes challenged with Aspergillus fumigatus: differential role of Toll-like receptors. Antimicrob Agents Chemother. 2008 Sep;52(9):3301-6. PMID: 18625774.

 

Varanasi NL, Baskaran I, Alangaden GJ, et al. Novel effect of voriconazole on conidiation of Aspergillus species. Int J Antimicrob Agents. 2004 Jan;23(1):72-9. PMID: 14732317.

" T "UN number: 2811     Class: 6.1     Packing Group: III

Proper shipping name: Toxic solid, organic, n.o.s. (Voriconazole)"

LKT C0268 Carbadox 25 g 46.4 Livestock antibiotic and growth promoter. (2-Quinoxalinylmethylene)hydrazinecarboxylic acid methyl ester N,N'-dioxide Fortigro; Mecadox 6804-07-5 ≥98% 262.22 C11H10N4O4 COC(=O)N=NC=C1C=[N+](C2=CC=CC=C2N1O)[O-] Ambient Ambient Practically insoluble in water. "Wattanaphansak S, Singer RS, Gebhart CJ. In vitro antimicrobial activity against 10 North American and European Lawsonia intracellularis isolates. Vet Microbiol. 2009 Mar 2;134(3-4):305-10. PMID: 18823723.

 

Laine T, Yliaho M, Myllys V, et al. The effect of antimicrobial growth promoter withdrawal on the health of weaned pigs in Finland. Prev Vet Med. 2004 Dec 15;66(1-4):163-74. PMID: 15579342.

 

Williams BJ, Shively JE. In vitro antitreponemal activities of carbadox, virginiamycin, olaquindox, and tylosin as indices of their effectiveness for preventing swine dysentery. Vet Med Small Anim Clin. 1978 Mar;73(3):349-51. PMID: 418551.

" Carc., F "UN number: 1325     Class: 4.1     Packing Group: II

Proper shipping name: Flammable solids, organic, n.o.s. (Carbadox)

"

LKT V5886 Voriconazole 250 mg 200.8 Triazole; 14α demethylase inhibitor. (2R,3S)-2-(2,4-difluorophenyl)-3-(5-fluoropyrimidin-4-yl)-1-(1,2,4-triazol-1-yl)butan-2-ol 137234-62-9 ≥98% 349.31 C16H14F3N5O CC(C1=NC=NC=C1F)C(CN2C=NC=N2)(C3=C(C=C(C=C3)F)F)O Ambient Ambient "Thompson GR 3rd, Lewis JS 2nd. Pharmacology and clinical use of voriconazole. Expert Opin Drug Metab Toxicol. 2010 Jan;6(1):83-94. PMID: 19947892.

 

Simitsopoulou M, Roilides E, Paliogianni F, et al. Immunomodulatory effects of voriconazole on monocytes challenged with Aspergillus fumigatus: differential role of Toll-like receptors. Antimicrob Agents Chemother. 2008 Sep;52(9):3301-6. PMID: 18625774.

 

Varanasi NL, Baskaran I, Alangaden GJ, et al. Novel effect of voriconazole on conidiation of Aspergillus species. Int J Antimicrob Agents. 2004 Jan;23(1):72-9. PMID: 14732317.

" T "UN number: 2811     Class: 6.1     Packing Group: III

Proper shipping name: Toxic solid, organic, n.o.s. (Voriconazole)"

LKT C0268 Carbadox 100 g 138.9 Livestock antibiotic and growth promoter. (2-Quinoxalinylmethylene)hydrazinecarboxylic acid methyl ester N,N'-dioxide Fortigro; Mecadox 6804-07-5 ≥98% 262.22 C11H10N4O4 COC(=O)N=NC=C1C=[N+](C2=CC=CC=C2N1O)[O-] Ambient Ambient Practically insoluble in water. "Wattanaphansak S, Singer RS, Gebhart CJ. In vitro antimicrobial activity against 10 North American and European Lawsonia intracellularis isolates. Vet Microbiol. 2009 Mar 2;134(3-4):305-10. PMID: 18823723.

 

Laine T, Yliaho M, Myllys V, et al. The effect of antimicrobial growth promoter withdrawal on the health of weaned pigs in Finland. Prev Vet Med. 2004 Dec 15;66(1-4):163-74. PMID: 15579342.

 

Williams BJ, Shively JE. In vitro antitreponemal activities of carbadox, virginiamycin, olaquindox, and tylosin as indices of their effectiveness for preventing swine dysentery. Vet Med Small Anim Clin. 1978 Mar;73(3):349-51. PMID: 418551.

" Carc., F "UN number: 1325     Class: 4.1     Packing Group: II

Proper shipping name: Flammable solids, organic, n.o.s. (Carbadox)

"

LKT V5886 Voriconazole 1 g 627.8 Triazole; 14α demethylase inhibitor. (2R,3S)-2-(2,4-difluorophenyl)-3-(5-fluoropyrimidin-4-yl)-1-(1,2,4-triazol-1-yl)butan-2-ol 137234-62-9 ≥98% 349.31 C16H14F3N5O CC(C1=NC=NC=C1F)C(CN2C=NC=N2)(C3=C(C=C(C=C3)F)F)O Ambient Ambient "Thompson GR 3rd, Lewis JS 2nd. Pharmacology and clinical use of voriconazole. Expert Opin Drug Metab Toxicol. 2010 Jan;6(1):83-94. PMID: 19947892.

 

Simitsopoulou M, Roilides E, Paliogianni F, et al. Immunomodulatory effects of voriconazole on monocytes challenged with Aspergillus fumigatus: differential role of Toll-like receptors. Antimicrob Agents Chemother. 2008 Sep;52(9):3301-6. PMID: 18625774.

 

Varanasi NL, Baskaran I, Alangaden GJ, et al. Novel effect of voriconazole on conidiation of Aspergillus species. Int J Antimicrob Agents. 2004 Jan;23(1):72-9. PMID: 14732317.

" T "UN number: 2811     Class: 6.1     Packing Group: III

Proper shipping name: Toxic solid, organic, n.o.s. (Voriconazole)"

LKT C0270 Carbamazepine 1 g 27.8 GABA potentiator, voltage-gated Na+ and ATP-sensitive K+ channel blocker. 5H-Dibenz[b,f]azepine-5-carboxamide Biston; Carbatrol; Epitol; Sirtal; Telesmin; Timonil 298-46-4 ≥98% 236.27 C15H12N2O C1=CC=C2C(=C1)C=CC3=CC=CC=C3N2C(=O)N Ambient 4°C Soluble in alcohol, acetone or propylene glycol. Practically insoluble in water. "Gómez CD, Buijs RM, Sitges M. The anti-seizure drugs vinpocetine and carbamazepine, but not valproic acid, reduce inflammatory IL-1β and TNF-α expression in rat hippocampus. J Neurochem. 2014 Jun 5. [Epub ahead of print]. PMID: 24903676.

 

Zhou Q, Chen PC, Devaraneni PK, et al. Carbamazepine inhibits ATP-sensitive potassium channel activity by disrupting channel response to MgADP. Channels (Austin). 2014 May 21;8(4). [Epub ahead of print]. PMID: 24849284.

 

Rahman W, Dickenson AH. Voltage gated sodium and calcium channel blockers for the treatment of chronic inflammatory pain. Neurosci Lett. 2013 Dec 17;557 Pt A:19-26. PMID: 23941888.

 

Bialer M. Why are antiepileptic drugs used for nonepileptic conditions? Epilepsia. 2012 Dec;53 Suppl 7:26-33. PMID: 23153207.

" Xn Not dangerous goods.

LKT C0270 Carbamazepine 5 g 57.8 GABA potentiator, voltage-gated Na+ and ATP-sensitive K+ channel blocker. 5H-Dibenz[b,f]azepine-5-carboxamide Biston; Carbatrol; Epitol; Sirtal; Telesmin; Timonil 298-46-4 ≥98% 236.27 C15H12N2O C1=CC=C2C(=C1)C=CC3=CC=CC=C3N2C(=O)N Ambient 4°C Soluble in alcohol, acetone or propylene glycol. Practically insoluble in water. "Gómez CD, Buijs RM, Sitges M. The anti-seizure drugs vinpocetine and carbamazepine, but not valproic acid, reduce inflammatory IL-1β and TNF-α expression in rat hippocampus. J Neurochem. 2014 Jun 5. [Epub ahead of print]. PMID: 24903676.

 

Zhou Q, Chen PC, Devaraneni PK, et al. Carbamazepine inhibits ATP-sensitive potassium channel activity by disrupting channel response to MgADP. Channels (Austin). 2014 May 21;8(4). [Epub ahead of print]. PMID: 24849284.

 

Rahman W, Dickenson AH. Voltage gated sodium and calcium channel blockers for the treatment of chronic inflammatory pain. Neurosci Lett. 2013 Dec 17;557 Pt A:19-26. PMID: 23941888.

 

Bialer M. Why are antiepileptic drugs used for nonepileptic conditions? Epilepsia. 2012 Dec;53 Suppl 7:26-33. PMID: 23153207.

" Xn Not dangerous goods.

LKT C0270 Carbamazepine 25 g 184.8 GABA potentiator, voltage-gated Na+ and ATP-sensitive K+ channel blocker. 5H-Dibenz[b,f]azepine-5-carboxamide Biston; Carbatrol; Epitol; Sirtal; Telesmin; Timonil 298-46-4 ≥98% 236.27 C15H12N2O C1=CC=C2C(=C1)C=CC3=CC=CC=C3N2C(=O)N Ambient 4°C Soluble in alcohol, acetone or propylene glycol. Practically insoluble in water. "Gómez CD, Buijs RM, Sitges M. The anti-seizure drugs vinpocetine and carbamazepine, but not valproic acid, reduce inflammatory IL-1β and TNF-α expression in rat hippocampus. J Neurochem. 2014 Jun 5. [Epub ahead of print]. PMID: 24903676.

 

Zhou Q, Chen PC, Devaraneni PK, et al. Carbamazepine inhibits ATP-sensitive potassium channel activity by disrupting channel response to MgADP. Channels (Austin). 2014 May 21;8(4). [Epub ahead of print]. PMID: 24849284.

 

Rahman W, Dickenson AH. Voltage gated sodium and calcium channel blockers for the treatment of chronic inflammatory pain. Neurosci Lett. 2013 Dec 17;557 Pt A:19-26. PMID: 23941888.

 

Bialer M. Why are antiepileptic drugs used for nonepileptic conditions? Epilepsia. 2012 Dec;53 Suppl 7:26-33. PMID: 23153207.

" Xn Not dangerous goods.

LKT V5734 Vorinostat 100 mg 159.4 HDAC inhibitor, RNA splicing inhibitor. N-hydroxy-N'-phenyl-octanediamide suberoylanilide hydroxamic acid, SAHA, Zolinza 149647-78-9 ≥98% 264.32 C14H20N2O3 C1=CC=C(C=C1)NC(=O)CCCCCCC(=O)NO Ambient Ambient "Legartová S, Stixová L, Strnad H, et al. Basic nuclear processes affected by histone acetyltransferases and histone deacetylase inhibitors. Epigenomics. 2013 Aug;5(4):379-96. PMID: 23895652.

 

Matsumoto Y, Morinobu S, Yamamoto S, et al. Vorinostat ameliorates impaired fear extinction possibly via the hippocampal NMDA-CaMKII pathway in an animal model of posttraumatic stress disorder. Psychopharmacology (Berl). 2013 Sep;229(1):51-62. PMID: 23584669.

 

Silva G, Cardoso BA, Belo H, et al. Vorinostat induces apoptosis and differentiation in myeloid malignancies: genetic and molecular mechanisms. PLoS One. 2013;8(1):e53766. PMID: 23320102.

 

Lee EQ, Puduvalli VK, Reid JM, et al. Phase I study of vorinostat in combination with temozolomide in patients with high-grade gliomas: North American Brain Tumor Consortium Study 04-03. Clin Cancer Res. 2012 Nov 1;18(21):6032-9. PMID: 22923449.

 

Archin NM, Liberty AL, Kashuba AD, et al. Administration of vorinostat disrupts HIV-1 latency in patients on antiretroviral therapy. Nature. 2012 Jul 25;487(7408):482-5. PMID: 22837004.

 

Asklund T, Kvarnbrink S, Holmlund C, et al. Synergistic killing of glioblastoma stem-like cells by bortezomib and HDAC inhibitors. Anticancer Res. 2012 Jul;32(7):2407-13. PMID: 22753697.

 

Xu J, Sampath D, Lang FF, et al. Vorinostat modulates cell cycle regulatory proteins in glioma cells and human glioma slice cultures. J Neurooncol. 2011 Nov;105(2):241-51. PMID: 21598070.

" Not dangerous goods.

LKT V5734 Vorinostat 250 mg 356.3 HDAC inhibitor, RNA splicing inhibitor. N-hydroxy-N'-phenyl-octanediamide suberoylanilide hydroxamic acid, SAHA, Zolinza 149647-78-9 ≥98% 264.32 C14H20N2O3 C1=CC=C(C=C1)NC(=O)CCCCCCC(=O)NO Ambient Ambient "Legartová S, Stixová L, Strnad H, et al. Basic nuclear processes affected by histone acetyltransferases and histone deacetylase inhibitors. Epigenomics. 2013 Aug;5(4):379-96. PMID: 23895652.

 

Matsumoto Y, Morinobu S, Yamamoto S, et al. Vorinostat ameliorates impaired fear extinction possibly via the hippocampal NMDA-CaMKII pathway in an animal model of posttraumatic stress disorder. Psychopharmacology (Berl). 2013 Sep;229(1):51-62. PMID: 23584669.

 

Silva G, Cardoso BA, Belo H, et al. Vorinostat induces apoptosis and differentiation in myeloid malignancies: genetic and molecular mechanisms. PLoS One. 2013;8(1):e53766. PMID: 23320102.

 

Lee EQ, Puduvalli VK, Reid JM, et al. Phase I study of vorinostat in combination with temozolomide in patients with high-grade gliomas: North American Brain Tumor Consortium Study 04-03. Clin Cancer Res. 2012 Nov 1;18(21):6032-9. PMID: 22923449.

 

Archin NM, Liberty AL, Kashuba AD, et al. Administration of vorinostat disrupts HIV-1 latency in patients on antiretroviral therapy. Nature. 2012 Jul 25;487(7408):482-5. PMID: 22837004.

 

Asklund T, Kvarnbrink S, Holmlund C, et al. Synergistic killing of glioblastoma stem-like cells by bortezomib and HDAC inhibitors. Anticancer Res. 2012 Jul;32(7):2407-13. PMID: 22753697.

 

Xu J, Sampath D, Lang FF, et al. Vorinostat modulates cell cycle regulatory proteins in glioma cells and human glioma slice cultures. J Neurooncol. 2011 Nov;105(2):241-51. PMID: 21598070.

" Not dangerous goods.

LKT V5734 Vorinostat 1 g 1200.2 HDAC inhibitor, RNA splicing inhibitor. N-hydroxy-N'-phenyl-octanediamide suberoylanilide hydroxamic acid, SAHA, Zolinza 149647-78-9 ≥98% 264.32 C14H20N2O3 C1=CC=C(C=C1)NC(=O)CCCCCCC(=O)NO Ambient Ambient "Legartová S, Stixová L, Strnad H, et al. Basic nuclear processes affected by histone acetyltransferases and histone deacetylase inhibitors. Epigenomics. 2013 Aug;5(4):379-96. PMID: 23895652.

 

Matsumoto Y, Morinobu S, Yamamoto S, et al. Vorinostat ameliorates impaired fear extinction possibly via the hippocampal NMDA-CaMKII pathway in an animal model of posttraumatic stress disorder. Psychopharmacology (Berl). 2013 Sep;229(1):51-62. PMID: 23584669.

 

Silva G, Cardoso BA, Belo H, et al. Vorinostat induces apoptosis and differentiation in myeloid malignancies: genetic and molecular mechanisms. PLoS One. 2013;8(1):e53766. PMID: 23320102.

 

Lee EQ, Puduvalli VK, Reid JM, et al. Phase I study of vorinostat in combination with temozolomide in patients with high-grade gliomas: North American Brain Tumor Consortium Study 04-03. Clin Cancer Res. 2012 Nov 1;18(21):6032-9. PMID: 22923449.

 

Archin NM, Liberty AL, Kashuba AD, et al. Administration of vorinostat disrupts HIV-1 latency in patients on antiretroviral therapy. Nature. 2012 Jul 25;487(7408):482-5. PMID: 22837004.

 

Asklund T, Kvarnbrink S, Holmlund C, et al. Synergistic killing of glioblastoma stem-like cells by bortezomib and HDAC inhibitors. Anticancer Res. 2012 Jul;32(7):2407-13. PMID: 22753697.

 

Xu J, Sampath D, Lang FF, et al. Vorinostat modulates cell cycle regulatory proteins in glioma cells and human glioma slice cultures. J Neurooncol. 2011 Nov;105(2):241-51. PMID: 21598070.

" Not dangerous goods.

LKT C0275 Castanospermine 10 mg 143.1 O-GlcNAcase inhibitor. 79831-76-8 ≥98% 189.21 C8H15NO4 C1CN2CC(C(C(C2C1O)O)O)O Ambient 4°C 20 mg/ml HCl "Hibberd AD, Trevillian PR, Clark DA, et al. The effects of Castanospermine, an oligosaccharide processing inhibitor, on mononuclear/endothelial cell binding and the expression of cell adhesion molecules. Transpl Immunol. 2012 Aug;27(1):39-47. PMID: 22647882.

 

Macauley MS, He Y, Gloster TM, et al. Inhibition of O-GlcNAcase using a potent and cell-permeable inhibitor does not induce insulin resistance in 3T3-L1 adipocytes. Chem Biol. 2010 Sep 24;17(9):937-48. Erratum in: Chem Biol. 2010 Oct 29;17(10):1161. PMID: 20851343.

 

Marcus NY, Perlmutter DH. Glucosidase and mannosidase inhibitors mediate increased secretion of mutant alpha1 antitrypsin Z. J Biol Chem. 2000 Jan 21;275(3):1987-92. PMID: 10636901.

 

Willenborg DO, Parish CR, Cowden WB. Inhibition of adjuvant arthritis in the rat by phosphosugars and the alpha-glucosidase inhibitor castanospermine. Immunol Cell Biol. 1992 Dec;70 ( Pt 6):369-77. PMID: 1289239.

 

Sunkara PS, Bowlin TL, Liu PS, et al. Antiretroviral activity of castanospermine and deoxynojirimycin, specific inhibitors of glycoprotein processing. Biochem Biophys Res Commun. 1987 Oct 14;148(1):206-10. PMID: 2960321.

 

Humphries MJ, Matsumoto K, White SL, et al. Inhibition of experimental metastasis by castanospermine in mice: blockage of two distinct stages of tumor colonization by oligosaccharide processing inhibitors. Cancer Res. 1986 Oct;46(10):5215-22. PMID: 3093061.

" Xn, Xi Not dangerous goods.

LKT C0275 Castanospermine 50 mg 315.1 O-GlcNAcase inhibitor. 79831-76-8 ≥98% 189.21 C8H15NO4 C1CN2CC(C(C(C2C1O)O)O)O Ambient 4°C 20 mg/ml HCl "Hibberd AD, Trevillian PR, Clark DA, et al. The effects of Castanospermine, an oligosaccharide processing inhibitor, on mononuclear/endothelial cell binding and the expression of cell adhesion molecules. Transpl Immunol. 2012 Aug;27(1):39-47. PMID: 22647882.

 

Macauley MS, He Y, Gloster TM, et al. Inhibition of O-GlcNAcase using a potent and cell-permeable inhibitor does not induce insulin resistance in 3T3-L1 adipocytes. Chem Biol. 2010 Sep 24;17(9):937-48. Erratum in: Chem Biol. 2010 Oct 29;17(10):1161. PMID: 20851343.

 

Marcus NY, Perlmutter DH. Glucosidase and mannosidase inhibitors mediate increased secretion of mutant alpha1 antitrypsin Z. J Biol Chem. 2000 Jan 21;275(3):1987-92. PMID: 10636901.

 

Willenborg DO, Parish CR, Cowden WB. Inhibition of adjuvant arthritis in the rat by phosphosugars and the alpha-glucosidase inhibitor castanospermine. Immunol Cell Biol. 1992 Dec;70 ( Pt 6):369-77. PMID: 1289239.

 

Sunkara PS, Bowlin TL, Liu PS, et al. Antiretroviral activity of castanospermine and deoxynojirimycin, specific inhibitors of glycoprotein processing. Biochem Biophys Res Commun. 1987 Oct 14;148(1):206-10. PMID: 2960321.

 

Humphries MJ, Matsumoto K, White SL, et al. Inhibition of experimental metastasis by castanospermine in mice: blockage of two distinct stages of tumor colonization by oligosaccharide processing inhibitors. Cancer Res. 1986 Oct;46(10):5215-22. PMID: 3093061.

" Xn, Xi Not dangerous goods.

LKT C0275 Castanospermine 100 mg 509.7 O-GlcNAcase inhibitor. 79831-76-8 ≥98% 189.21 C8H15NO4 C1CN2CC(C(C(C2C1O)O)O)O Ambient 4°C 20 mg/ml HCl "Hibberd AD, Trevillian PR, Clark DA, et al. The effects of Castanospermine, an oligosaccharide processing inhibitor, on mononuclear/endothelial cell binding and the expression of cell adhesion molecules. Transpl Immunol. 2012 Aug;27(1):39-47. PMID: 22647882.

 

Macauley MS, He Y, Gloster TM, et al. Inhibition of O-GlcNAcase using a potent and cell-permeable inhibitor does not induce insulin resistance in 3T3-L1 adipocytes. Chem Biol. 2010 Sep 24;17(9):937-48. Erratum in: Chem Biol. 2010 Oct 29;17(10):1161. PMID: 20851343.

 

Marcus NY, Perlmutter DH. Glucosidase and mannosidase inhibitors mediate increased secretion of mutant alpha1 antitrypsin Z. J Biol Chem. 2000 Jan 21;275(3):1987-92. PMID: 10636901.

 

Willenborg DO, Parish CR, Cowden WB. Inhibition of adjuvant arthritis in the rat by phosphosugars and the alpha-glucosidase inhibitor castanospermine. Immunol Cell Biol. 1992 Dec;70 ( Pt 6):369-77. PMID: 1289239.

 

Sunkara PS, Bowlin TL, Liu PS, et al. Antiretroviral activity of castanospermine and deoxynojirimycin, specific inhibitors of glycoprotein processing. Biochem Biophys Res Commun. 1987 Oct 14;148(1):206-10. PMID: 2960321.

 

Humphries MJ, Matsumoto K, White SL, et al. Inhibition of experimental metastasis by castanospermine in mice: blockage of two distinct stages of tumor colonization by oligosaccharide processing inhibitors. Cancer Res. 1986 Oct;46(10):5215-22. PMID: 3093061.

" Xn, Xi Not dangerous goods.

LKT C0278 (+)-Catechin 1 mg 57.8 Flavanol originally found in Camilla (green tea); MAO-B inhibitor. (2R-trans)-2-(3,4-Dihydroxyphenyl)-3,4-dihydro-2H- 1-benzopyran-3,5,7-triol Catechol; Catechinic acid; Dexcyanidanol; Cyanidol; Catergen 154-23-4 ≥99% 290.27 C15H14O6 C1C(C(OC2=CC(=CC(=C21)O)O)C3=CC(=C(C=C3)O)O)O Ambient -20°C Soluble in hot water, alcohol acetone, and glacial acetic acid. "Chang CF, Cho S, Wang J. (-)-Epicatechin protects hemorrhagic brain via synergistic Nrf2 pathways. Ann Clin Transl Neurol. 2014 Apr 1;1(4):258-271. PMID: 24741667.

 

Nogueira L, Ramirez-Sanchez I, Perkins GA, et al. (-)-Epicatechin enhances fatigue resistance and oxidative capacity in mouse muscle. J Physiol. 2011 Sep 15;589(Pt 18):4615-31. PMID: 21788351.

 

Saul N, Pietsch K, Menzel R, et al. Catechin induced longevity in C. elegans: from key regulator genes to disposable soma. Mech Ageing Dev. 2009 Aug;130(8):477-86. PMID: 19501612.

 

Auclair S, Milenkovic D, Besson C, et al. Catechin reduces atherosclerotic lesion development in apo E-deficient mice: a transcriptomic study. Atherosclerosis. 2009 Jun;204(2):e21-7. PMID: 19152914.

 

Hou WC, Lin RD, Chen CT, et al. Monoamine oxidase B (MAO-B) inhibition by active principles from Uncaria rhynchophylla. J Ethnopharmacol. 2005 Aug 22;100(1-2):216-20. PMID: 15890481.

 

Weyant MJ, Carothers AM, Dannenberg AJ, et al. (+)-Catechin inhibits intestinal tumor formation and suppresses focal adhesion kinase activation in the min/+ mouse. Cancer Res. 2001 Jan 1;61(1):118-25. PMID: 11196148.

 

Mangiapane H, Thomson J, Salter A, et al. The inhibition of the oxidation of low density lipoprotein by (+)-catechin, a naturally occurring flavonoid. Biochem Pharmacol. 1992 Feb 4;43(3):445-50. PMID: 1540202.

 

Reimann HJ, Lorenz W, Fischer M, et al. Histamine and acute haemorrhagic lesions in rat gastric mucosa: prevention of stress ulcer formation by (+)-catechin, an inhibitor of specific histidine decarboxylase in vitro. Agents Actions. 1977 Mar;7(1):69-73. PMID: 871094.

" Xi Not dangerous goods.

LKT C0278 (+)-Catechin 5 mg 144.1 Flavanol originally found in Camilla (green tea); MAO-B inhibitor. (2R-trans)-2-(3,4-Dihydroxyphenyl)-3,4-dihydro-2H- 1-benzopyran-3,5,7-triol Catechol; Catechinic acid; Dexcyanidanol; Cyanidol; Catergen 154-23-4 ≥99% 290.27 C15H14O6 C1C(C(OC2=CC(=CC(=C21)O)O)C3=CC(=C(C=C3)O)O)O Ambient -20°C Soluble in hot water, alcohol acetone, and glacial acetic acid. "Chang CF, Cho S, Wang J. (-)-Epicatechin protects hemorrhagic brain via synergistic Nrf2 pathways. Ann Clin Transl Neurol. 2014 Apr 1;1(4):258-271. PMID: 24741667.

 

Nogueira L, Ramirez-Sanchez I, Perkins GA, et al. (-)-Epicatechin enhances fatigue resistance and oxidative capacity in mouse muscle. J Physiol. 2011 Sep 15;589(Pt 18):4615-31. PMID: 21788351.

 

Saul N, Pietsch K, Menzel R, et al. Catechin induced longevity in C. elegans: from key regulator genes to disposable soma. Mech Ageing Dev. 2009 Aug;130(8):477-86. PMID: 19501612.

 

Auclair S, Milenkovic D, Besson C, et al. Catechin reduces atherosclerotic lesion development in apo E-deficient mice: a transcriptomic study. Atherosclerosis. 2009 Jun;204(2):e21-7. PMID: 19152914.

 

Hou WC, Lin RD, Chen CT, et al. Monoamine oxidase B (MAO-B) inhibition by active principles from Uncaria rhynchophylla. J Ethnopharmacol. 2005 Aug 22;100(1-2):216-20. PMID: 15890481.

 

Weyant MJ, Carothers AM, Dannenberg AJ, et al. (+)-Catechin inhibits intestinal tumor formation and suppresses focal adhesion kinase activation in the min/+ mouse. Cancer Res. 2001 Jan 1;61(1):118-25. PMID: 11196148.

 

Mangiapane H, Thomson J, Salter A, et al. The inhibition of the oxidation of low density lipoprotein by (+)-catechin, a naturally occurring flavonoid. Biochem Pharmacol. 1992 Feb 4;43(3):445-50. PMID: 1540202.

 

Reimann HJ, Lorenz W, Fischer M, et al. Histamine and acute haemorrhagic lesions in rat gastric mucosa: prevention of stress ulcer formation by (+)-catechin, an inhibitor of specific histidine decarboxylase in vitro. Agents Actions. 1977 Mar;7(1):69-73. PMID: 871094.

" Xi Not dangerous goods.

LKT C0344 Calphostin C 100 µg 406.4 Found in Cladosporium; PKC inhibitor. UCN-1028c 121263-19-2 ≥95% 790.76 C44H38O14 CC(CC1=C(C(=C2C(=O)C=C(C3=C4C(=CC(=O)C5=C(C(=C(C(=C45)C1=C32)CC(C)OC(=O)OC6=CC=C(C=C6)O)OC)O)OC)OC)O)OC)OC(=O)C7=CC=CC=C7 Ambient -20°C Soluble in DMSO, ethanol, or DMF. "De Vita F, Riccardi M, Malanga D, et al. PKC-dependent phosphorylation of p27 at T198 contributes to p27 stabilization and cell cycle arrest. Cell Cycle. 2012 Apr 15;11(8):1583-92. PMID: 22441823.

 

Robitaille K, Daviau A, Lachance G, et al. Calphostin C-induced apoptosis is mediated by a tissue transglutaminase-dependent mechanism involving the DLK/JNK signaling pathway. Cell Death Differ. 2008 Sep;15(9):1522-31. PMID: 18497756.

 

Kobayashi E, Ando K, Nakano H, et al. Calphostins (UCN-1028), novel and specific inhibitors of protein kinase C. I. Fermentation, isolation, physico-chemical properties and biological activities. J Antibiot (Tokyo). 1989 Oct;42(10):1470-4. PMID: 2478514.

" Not dangerous goods.

LKT V5725 Voglibose 10 mg 113.9 α-glucosidase inhibitor, potential GLP-1 agonist, potential ATP-sensitive K+ channel activator. (1S,2S,3R,4S,5S)-5-(1,3-dihydroxypropan-2-ylamino)-1-(hydroxymethyl)cyclohexane-1,2,3,4-tetrol 83480-29-9 ≥98% 267.28 C10H21NO7 C1C(C(C(C(C1(CO)O)O)O)O)NC(CO)CO Ambient Ambient "Bin BH, Seo J, Yang SH, et al. Novel inhibitory effect of the antidiabetic drug voglibose on melanogenesis. Exp Dermatol. 2013 Aug;22(8):541-6. PMID: 23879813.

 

Iwasa M, Kobayashi H, Yasuda S, et al. Antidiabetic drug voglibose is protective against ischemia-reperfusion injury through glucagon-like peptide 1 receptors and the phosphoinositide 3-kinase-Akt-endothelial nitric oxide synthase pathway in rabbits. J Cardiovasc Pharmacol. 2010 Jun;55(6):625-34. Erratum in: J Cardiovasc Pharmacol. 2012 Jul;60(1):108.  PMID: 20351564.

 

Kawamori R, Tajima N, Iwamoto Y, et al. Voglibose for prevention of type 2 diabetes mellitus: a randomised, double-blind trial in Japanese individuals with impaired glucose tolerance. Lancet. 2009 May 9;373(9675):1607-14. PMID: 19395079.

 

Moritoh Y, Takeuchi K, Hazama M. Chronic administration of voglibose, an alpha-glucosidase inhibitor, increases active glucagon-like peptide-1 levels by increasing its secretion and decreasing dipeptidyl peptidase-4 activity in ob/ob mice. J Pharmacol Exp Ther. 2009 May;329(2):669-76. PMID: 19208898.

 

Satoh N, Shimatsu A, Yamada K, et al. An alpha-glucosidase inhibitor, voglibose, reduces oxidative stress markers and soluble intercellular adhesion molecule 1 in obese type 2 diabetic patients. Metabolism. 2006 Jun;55(6):786-93. PMID: 16713439.

" None Not dangerous goods.

LKT V5725 Voglibose 25 mg 226.1 α-glucosidase inhibitor, potential GLP-1 agonist, potential ATP-sensitive K+ channel activator. (1S,2S,3R,4S,5S)-5-(1,3-dihydroxypropan-2-ylamino)-1-(hydroxymethyl)cyclohexane-1,2,3,4-tetrol 83480-29-9 ≥98% 267.28 C10H21NO7 C1C(C(C(C(C1(CO)O)O)O)O)NC(CO)CO Ambient Ambient "Bin BH, Seo J, Yang SH, et al. Novel inhibitory effect of the antidiabetic drug voglibose on melanogenesis. Exp Dermatol. 2013 Aug;22(8):541-6. PMID: 23879813.

 

Iwasa M, Kobayashi H, Yasuda S, et al. Antidiabetic drug voglibose is protective against ischemia-reperfusion injury through glucagon-like peptide 1 receptors and the phosphoinositide 3-kinase-Akt-endothelial nitric oxide synthase pathway in rabbits. J Cardiovasc Pharmacol. 2010 Jun;55(6):625-34. Erratum in: J Cardiovasc Pharmacol. 2012 Jul;60(1):108.  PMID: 20351564.

 

Kawamori R, Tajima N, Iwamoto Y, et al. Voglibose for prevention of type 2 diabetes mellitus: a randomised, double-blind trial in Japanese individuals with impaired glucose tolerance. Lancet. 2009 May 9;373(9675):1607-14. PMID: 19395079.

 

Moritoh Y, Takeuchi K, Hazama M. Chronic administration of voglibose, an alpha-glucosidase inhibitor, increases active glucagon-like peptide-1 levels by increasing its secretion and decreasing dipeptidyl peptidase-4 activity in ob/ob mice. J Pharmacol Exp Ther. 2009 May;329(2):669-76. PMID: 19208898.

 

Satoh N, Shimatsu A, Yamada K, et al. An alpha-glucosidase inhibitor, voglibose, reduces oxidative stress markers and soluble intercellular adhesion molecule 1 in obese type 2 diabetic patients. Metabolism. 2006 Jun;55(6):786-93. PMID: 16713439.

" None Not dangerous goods.

LKT V5725 Voglibose 100 mg 669.7 α-glucosidase inhibitor, potential GLP-1 agonist, potential ATP-sensitive K+ channel activator. (1S,2S,3R,4S,5S)-5-(1,3-dihydroxypropan-2-ylamino)-1-(hydroxymethyl)cyclohexane-1,2,3,4-tetrol 83480-29-9 ≥98% 267.28 C10H21NO7 C1C(C(C(C(C1(CO)O)O)O)O)NC(CO)CO Ambient Ambient "Bin BH, Seo J, Yang SH, et al. Novel inhibitory effect of the antidiabetic drug voglibose on melanogenesis. Exp Dermatol. 2013 Aug;22(8):541-6. PMID: 23879813.

 

Iwasa M, Kobayashi H, Yasuda S, et al. Antidiabetic drug voglibose is protective against ischemia-reperfusion injury through glucagon-like peptide 1 receptors and the phosphoinositide 3-kinase-Akt-endothelial nitric oxide synthase pathway in rabbits. J Cardiovasc Pharmacol. 2010 Jun;55(6):625-34. Erratum in: J Cardiovasc Pharmacol. 2012 Jul;60(1):108.  PMID: 20351564.

 

Kawamori R, Tajima N, Iwamoto Y, et al. Voglibose for prevention of type 2 diabetes mellitus: a randomised, double-blind trial in Japanese individuals with impaired glucose tolerance. Lancet. 2009 May 9;373(9675):1607-14. PMID: 19395079.

 

Moritoh Y, Takeuchi K, Hazama M. Chronic administration of voglibose, an alpha-glucosidase inhibitor, increases active glucagon-like peptide-1 levels by increasing its secretion and decreasing dipeptidyl peptidase-4 activity in ob/ob mice. J Pharmacol Exp Ther. 2009 May;329(2):669-76. PMID: 19208898.

 

Satoh N, Shimatsu A, Yamada K, et al. An alpha-glucosidase inhibitor, voglibose, reduces oxidative stress markers and soluble intercellular adhesion molecule 1 in obese type 2 diabetic patients. Metabolism. 2006 Jun;55(6):786-93. PMID: 16713439.

" None Not dangerous goods.

LKT V5254 Vincristine Sulfate 5 mg 47.6 Vinca alkaloid found in Catharanthus; microtubule polymerization inhibitor. 22-Oxovincaleukoblastine sulfate Kyocristine; Oncovin; Vincrex 2068-78-2 ≥82% 923.05 C46H56N4O10S H2SO4 CCC1(CC2CC(C3=C(CCN(C2)C1)C4=CC=CC=C4N3)(C5=C(C=C6C(=C5)C78CCN9C7C(C=CC9)(C(C(C8N6C=O)(C(=O)OC)O)OC(=O)C)CC)OC)C(=O)OC)O.OS(=O)(=O)O Hygroscopic. Light sensitive. Ambient -20°C Soluble in water. Slightly soluble in ethanol or chloroform. "Wang L, Xia ZJ, Huang HQ, et al. Cyclophosphamide, doxorubicin, vincristine, and prednisone (CHOP) in the treatment of stage IE/IIE extranodal natural killer/T cell lymphoma, nasal type: 13-year follow-up in 135 patients. Int J Hematol. 2012 Nov;96(5):617-23. PMID: 22983648.

 

Chen MB, Shen WX, Yang Y, et al. Activation of AMP-activated protein kinase is involved in vincristine-induced cell apoptosis in B16 melanoma cell. J Cell Physiol. 2011 Jul;226(7):1915-25. PMID: 21506122.

 

Jordan MA, Wilson L. Microtubules as a target for anticancer drugs. Nat Rev Cancer. 2004 Apr;4(4):253-65. PMID: 15057285.

" T "UN number: 2811     Class: 6.1     Packing Group: II

Proper shipping name: Toxic solid, organic, n.o.s. (Vincristine sulfate)"

LKT V5254 Vincristine Sulfate 10 mg 88.3 Vinca alkaloid found in Catharanthus; microtubule polymerization inhibitor. 22-Oxovincaleukoblastine sulfate Kyocristine; Oncovin; Vincrex 2068-78-2 ≥82% 923.05 C46H56N4O10S H2SO4 CCC1(CC2CC(C3=C(CCN(C2)C1)C4=CC=CC=C4N3)(C5=C(C=C6C(=C5)C78CCN9C7C(C=CC9)(C(C(C8N6C=O)(C(=O)OC)O)OC(=O)C)CC)OC)C(=O)OC)O.OS(=O)(=O)O Hygroscopic. Light sensitive. Ambient -20°C Soluble in water. Slightly soluble in ethanol or chloroform. "Wang L, Xia ZJ, Huang HQ, et al. Cyclophosphamide, doxorubicin, vincristine, and prednisone (CHOP) in the treatment of stage IE/IIE extranodal natural killer/T cell lymphoma, nasal type: 13-year follow-up in 135 patients. Int J Hematol. 2012 Nov;96(5):617-23. PMID: 22983648.

 

Chen MB, Shen WX, Yang Y, et al. Activation of AMP-activated protein kinase is involved in vincristine-induced cell apoptosis in B16 melanoma cell. J Cell Physiol. 2011 Jul;226(7):1915-25. PMID: 21506122.

 

Jordan MA, Wilson L. Microtubules as a target for anticancer drugs. Nat Rev Cancer. 2004 Apr;4(4):253-65. PMID: 15057285.

" T "UN number: 2811     Class: 6.1     Packing Group: II

Proper shipping name: Toxic solid, organic, n.o.s. (Vincristine sulfate)"

LKT C0346 Calyculin A 10 µg 233.3 Found in Discodermia; PP1 and PP2A inhibitor. N-[(3S)-3-[4-[(1E)-3-[(2R,3R,5R,7S,8S,9R)-2-[(1S,3S,- 4S,5R,6R,7E,9E,11E,13Z)-14-cyano-3,5-dihydroxy-1- methyoxy-4,6,8,9,13-pentamethyl-7,9,11,13-tetradeca- tetraenyl]-9-hydroxy-4,4,8-trimethyl-3-(phosphono- oxy)-1,6-dioxaspiro[4.5]dec-7-yl]-1-propenyl]-2-oxa- zolyl]-butyl]-4-deoxy-4-(dimethylamino)-5-O-methyl-L-ribonamide (-)-Calyculin A 101932-71-2 ≥98% 1009.17 C50H81N4O15P CC1C(CC2(C(C(C(O2)C(CC(C(C)C(C(C)C=C(C)C(=CC=CC(=CC#N)C)C)O)O)OC)OP(=O)(O)O)(C)C)OC1CC=CC3=COC(=N3)C(C)CCNC(=O)C(C(C(COC)N(C)C)O)O)O Protect from light. Ambient -20°C Soluble in DMSO or ethanol. "Iida Y, Yamamori S, Itakura M, et al. Protein phosphatase 2A dephosphorylates SNAP-25 through two distinct mechanisms in mouse brain synaptosomes. Neurosci Res. 2013 Mar;75(3):184-9. PMID: 23376809.

 

Palfrey HC, Pewitt EB. The ATP and Mg2+ dependence of Na(+)-K(+)-2Cl- cotransport reflects a requirement for protein phosphorylation: studies using calyculin A. Pflugers Arch. 1993 Nov;425(3-4):321-8. PMID: 8309793.

" T, Xi "UN number: 3462     Class: 6.1     Packing Group: III

Proper shipping name: Toxins, extracted from living sources, solid, n.o.s. (Calyculin A)

Reportable quantity (RQ):      Marine pollutant:  No     Poison inhalation hazard:  No"

LKT C0346 Calyculin A 50 µg 823.4 Found in Discodermia; PP1 and PP2A inhibitor. N-[(3S)-3-[4-[(1E)-3-[(2R,3R,5R,7S,8S,9R)-2-[(1S,3S,- 4S,5R,6R,7E,9E,11E,13Z)-14-cyano-3,5-dihydroxy-1- methyoxy-4,6,8,9,13-pentamethyl-7,9,11,13-tetradeca- tetraenyl]-9-hydroxy-4,4,8-trimethyl-3-(phosphono- oxy)-1,6-dioxaspiro[4.5]dec-7-yl]-1-propenyl]-2-oxa- zolyl]-butyl]-4-deoxy-4-(dimethylamino)-5-O-methyl-L-ribonamide (-)-Calyculin A 101932-71-2 ≥98% 1009.17 C50H81N4O15P CC1C(CC2(C(C(C(O2)C(CC(C(C)C(C(C)C=C(C)C(=CC=CC(=CC#N)C)C)O)O)OC)OP(=O)(O)O)(C)C)OC1CC=CC3=COC(=N3)C(C)CCNC(=O)C(C(C(COC)N(C)C)O)O)O Protect from light. Ambient -20°C Soluble in DMSO or ethanol. "Iida Y, Yamamori S, Itakura M, et al. Protein phosphatase 2A dephosphorylates SNAP-25 through two distinct mechanisms in mouse brain synaptosomes. Neurosci Res. 2013 Mar;75(3):184-9. PMID: 23376809.

 

Palfrey HC, Pewitt EB. The ATP and Mg2+ dependence of Na(+)-K(+)-2Cl- cotransport reflects a requirement for protein phosphorylation: studies using calyculin A. Pflugers Arch. 1993 Nov;425(3-4):321-8. PMID: 8309793.

" T, Xi "UN number: 3462     Class: 6.1     Packing Group: III

Proper shipping name: Toxins, extracted from living sources, solid, n.o.s. (Calyculin A)

Reportable quantity (RQ):      Marine pollutant:  No     Poison inhalation hazard:  No"

LKT L0107 Lactacystin 200 µg 615.4 Found in Streptomyces; proteasome inhibitor. 133343-34-7 ≥98% 376.43 C15H24N2O7S CC1C(C(NC1=O)(C(C(C)C)O)C(=O)SCC(C(=O)O)NC(=O)C)O Protect from light. Ambient -20°C Soluble DMSO or water. "Wang H, Zhang S, Zhong J, et al. The proteasome inhibitor lactacystin exerts its therapeutic effects on glioma via apoptosis: an in vitro and in vivo study. J Int Med Res. 2013 Feb;41(1):72-81. PMID: 23569132.

 

Barringhaus KG, Matsumura ME. The proteasome inhibitor lactacystin attenuates growth and migration of vascular smooth muscle cells and limits the response to arterial injury. Exp Clin Cardiol. 2007 Fall;12(3):119-24. PMID: 18650992.

 

Yao JH, Li YH, Wang ZZ, et al. Proteasome inhibitor lactacystin ablates liver injury induced by intestinal ischaemia-reperfusion. Clin Exp Pharmacol Physiol. 2007 Nov;34(11):1102-8. PMID: 17880361.

" Not dangerous goods.

LKT O4102 Okadaic Acid Ammonium 25 µg 148.2 Shellfish toxin produced by dinoflagellates and sea sponges; PP1 and PP2A inhibitor. 9,10-Deepithio-9,10-didehydroacanthifolicin ammonium salt 155716-06-6 ≥98% 822.04 C44H67O13 NH4 CC1CCC2(CCCCO2)OC1C(C)CC(C3C(=C)C(C4C(O3)CCC5(O4)CCC(O5)C=CC(C)C6CC(=CC7(O6)C(CCC(O7)CC(C)(C(=O)[O-])O)O)C)O)O.[NH4+] Protect from light. Ambient -20°C Soluble in ethanol, DMSO, water. "Kamat PK, Rai S, Swarnkar S, et al. Molecular and Cellular Mechanism of Okadaic Acid (OKA)-Induced Neurotoxicity: A Novel Tool for Alzheimer's Disease Therapeutic Application. Mol Neurobiol. 2014 Apr 8. [Epub ahead of print]. PMID: 24710687.

 

Chang NC, Lin AC, Hsu CC, et al. Okadaic Acid, a Bioactive Fatty Acid from Halichondria okadai, Stimulates Lipolysis in Rat Adipocytes: The Pivotal Role of Perilipin Translocation. Evid Based Complement Alternat Med. 2013;2013:545739. PMID: 24319476.

 

Mori N, Ishikawa C, Uchihara JN, et al. Protein phosphatase 2A as a potential target for treatment of adult T cell leukemia. Curr Cancer Drug Targets. 2013 Oct;13(8):829-42. PMID: 24015987.

" Xi, T "UN number: 3462     Class: 6.1     Packing Group: I

Proper shipping name: Toxins, extracted from living sources, solid, n.o.s. (Okadaic acid ammonium)"

LKT O4102 Okadaic Acid Ammonium 100 µg 466.8 Shellfish toxin produced by dinoflagellates and sea sponges; PP1 and PP2A inhibitor. 9,10-Deepithio-9,10-didehydroacanthifolicin ammonium salt 155716-06-6 ≥98% 822.04 C44H67O13 NH4 CC1CCC2(CCCCO2)OC1C(C)CC(C3C(=C)C(C4C(O3)CCC5(O4)CCC(O5)C=CC(C)C6CC(=CC7(O6)C(CCC(O7)CC(C)(C(=O)[O-])O)O)C)O)O.[NH4+] Protect from light. Ambient -20°C Soluble in ethanol, DMSO, water. "Kamat PK, Rai S, Swarnkar S, et al. Molecular and Cellular Mechanism of Okadaic Acid (OKA)-Induced Neurotoxicity: A Novel Tool for Alzheimer's Disease Therapeutic Application. Mol Neurobiol. 2014 Apr 8. [Epub ahead of print]. PMID: 24710687.

 

Chang NC, Lin AC, Hsu CC, et al. Okadaic Acid, a Bioactive Fatty Acid from Halichondria okadai, Stimulates Lipolysis in Rat Adipocytes: The Pivotal Role of Perilipin Translocation. Evid Based Complement Alternat Med. 2013;2013:545739. PMID: 24319476.

 

Mori N, Ishikawa C, Uchihara JN, et al. Protein phosphatase 2A as a potential target for treatment of adult T cell leukemia. Curr Cancer Drug Targets. 2013 Oct;13(8):829-42. PMID: 24015987.

" Xi, T "UN number: 3462     Class: 6.1     Packing Group: I

Proper shipping name: Toxins, extracted from living sources, solid, n.o.s. (Okadaic acid ammonium)"

LKT O4102 Okadaic Acid Ammonium 1 mg 3602.3 Shellfish toxin produced by dinoflagellates and sea sponges; PP1 and PP2A inhibitor. 9,10-Deepithio-9,10-didehydroacanthifolicin ammonium salt 155716-06-6 ≥98% 822.04 C44H67O13 NH4 CC1CCC2(CCCCO2)OC1C(C)CC(C3C(=C)C(C4C(O3)CCC5(O4)CCC(O5)C=CC(C)C6CC(=CC7(O6)C(CCC(O7)CC(C)(C(=O)[O-])O)O)C)O)O.[NH4+] Protect from light. Ambient -20°C Soluble in ethanol, DMSO, water. "Kamat PK, Rai S, Swarnkar S, et al. Molecular and Cellular Mechanism of Okadaic Acid (OKA)-Induced Neurotoxicity: A Novel Tool for Alzheimer's Disease Therapeutic Application. Mol Neurobiol. 2014 Apr 8. [Epub ahead of print]. PMID: 24710687.

 

Chang NC, Lin AC, Hsu CC, et al. Okadaic Acid, a Bioactive Fatty Acid from Halichondria okadai, Stimulates Lipolysis in Rat Adipocytes: The Pivotal Role of Perilipin Translocation. Evid Based Complement Alternat Med. 2013;2013:545739. PMID: 24319476.

 

Mori N, Ishikawa C, Uchihara JN, et al. Protein phosphatase 2A as a potential target for treatment of adult T cell leukemia. Curr Cancer Drug Targets. 2013 Oct;13(8):829-42. PMID: 24015987.

" Xi, T "UN number: 3462     Class: 6.1     Packing Group: I

Proper shipping name: Toxins, extracted from living sources, solid, n.o.s. (Okadaic acid ammonium)"

LKT O4104 Okadaic Acid Sodium 25 µg 159.3 Shellfish toxin produced by dinoflagellates and sea sponges; PP1 and PP2A inhibitor. 9,10-Deepithio-9,10-didehydroacanthifolicin sodium salt 209266-80-8 ≥98% 827 C44H67O13 Na CC1CCC2(CCCCO2)OC1C(C)CC(C3C(=C)C(C4C(O3)CCC5(O4)CCC(O5)C=CC(C)C6CC(=CC7(O6)C(CCC(O7)CC(C)(C(=O)[O-])O)O)C)O)O.[Na+] Ambient -20°C Soluble in ethanol, DMSO, or water. "Kamat PK, Rai S, Swarnkar S, et al. Molecular and Cellular Mechanism of Okadaic Acid (OKA)-Induced Neurotoxicity: A Novel Tool for Alzheimer's Disease Therapeutic Application. Mol Neurobiol. 2014 Apr 8. [Epub ahead of print]. PMID: 24710687.

 

Chang NC, Lin AC, Hsu CC, et al. Okadaic Acid, a Bioactive Fatty Acid from Halichondria okadai, Stimulates Lipolysis in Rat Adipocytes: The Pivotal Role of Perilipin Translocation. Evid Based Complement Alternat Med. 2013;2013:545739. PMID: 24319476.

 

Mori N, Ishikawa C, Uchihara JN, et al. Protein phosphatase 2A as a potential target for treatment of adult T cell leukemia. Curr Cancer Drug Targets. 2013 Oct;13(8):829-42. PMID: 24015987.

" Xi, T "UN number: 3462    Class: 6.1     Packing Group: I

Proper shipping name: Toxins, extracted from living sources, solid, n.o.s. (Okadaic acid sodium salt)"

LKT O4104 Okadaic Acid Sodium 100 µg 466.8 Shellfish toxin produced by dinoflagellates and sea sponges; PP1 and PP2A inhibitor. 9,10-Deepithio-9,10-didehydroacanthifolicin sodium salt 209266-80-8 ≥98% 827 C44H67O13 Na CC1CCC2(CCCCO2)OC1C(C)CC(C3C(=C)C(C4C(O3)CCC5(O4)CCC(O5)C=CC(C)C6CC(=CC7(O6)C(CCC(O7)CC(C)(C(=O)[O-])O)O)C)O)O.[Na+] Ambient -20°C Soluble in ethanol, DMSO, or water. "Kamat PK, Rai S, Swarnkar S, et al. Molecular and Cellular Mechanism of Okadaic Acid (OKA)-Induced Neurotoxicity: A Novel Tool for Alzheimer's Disease Therapeutic Application. Mol Neurobiol. 2014 Apr 8. [Epub ahead of print]. PMID: 24710687.

 

Chang NC, Lin AC, Hsu CC, et al. Okadaic Acid, a Bioactive Fatty Acid from Halichondria okadai, Stimulates Lipolysis in Rat Adipocytes: The Pivotal Role of Perilipin Translocation. Evid Based Complement Alternat Med. 2013;2013:545739. PMID: 24319476.

 

Mori N, Ishikawa C, Uchihara JN, et al. Protein phosphatase 2A as a potential target for treatment of adult T cell leukemia. Curr Cancer Drug Targets. 2013 Oct;13(8):829-42. PMID: 24015987.

" Xi, T "UN number: 3462    Class: 6.1     Packing Group: I

Proper shipping name: Toxins, extracted from living sources, solid, n.o.s. (Okadaic acid sodium salt)"

LKT O4104 Okadaic Acid Sodium 1 mg 3602.3 Shellfish toxin produced by dinoflagellates and sea sponges; PP1 and PP2A inhibitor. 9,10-Deepithio-9,10-didehydroacanthifolicin sodium salt 209266-80-8 ≥98% 827 C44H67O13 Na CC1CCC2(CCCCO2)OC1C(C)CC(C3C(=C)C(C4C(O3)CCC5(O4)CCC(O5)C=CC(C)C6CC(=CC7(O6)C(CCC(O7)CC(C)(C(=O)[O-])O)O)C)O)O.[Na+] Ambient -20°C Soluble in ethanol, DMSO, or water. "Kamat PK, Rai S, Swarnkar S, et al. Molecular and Cellular Mechanism of Okadaic Acid (OKA)-Induced Neurotoxicity: A Novel Tool for Alzheimer's Disease Therapeutic Application. Mol Neurobiol. 2014 Apr 8. [Epub ahead of print]. PMID: 24710687.

 

Chang NC, Lin AC, Hsu CC, et al. Okadaic Acid, a Bioactive Fatty Acid from Halichondria okadai, Stimulates Lipolysis in Rat Adipocytes: The Pivotal Role of Perilipin Translocation. Evid Based Complement Alternat Med. 2013;2013:545739. PMID: 24319476.

 

Mori N, Ishikawa C, Uchihara JN, et al. Protein phosphatase 2A as a potential target for treatment of adult T cell leukemia. Curr Cancer Drug Targets. 2013 Oct;13(8):829-42. PMID: 24015987.

" Xi, T "UN number: 3462    Class: 6.1     Packing Group: I

Proper shipping name: Toxins, extracted from living sources, solid, n.o.s. (Okadaic acid sodium salt)"

LKT H1669 Herbimycin A 100 µg 377.1 Benzoquinone ansamycin; HSP90, PKC, Src, Bcr-Abl inhibitor. Herbimycin 70563-58-5 ≥98% 574.66 C30H42N2O9 CC1CC(C(C(C=C(C(C(C=CC=C(C(=O)NC2=CC(=O)C=C(C1OC)C2=O)C)OC)OC(=O)N)C)C)OC)OC Protect from light. Ambient -20°C Soluble in DMSO. "Kasai S, Kikuchi H. The inhibitory mechanisms of the tyrosine kinase inhibitors herbimycin a, genistein, and tyrphostin B48 with regard to the function of the aryl hydrocarbon receptor in Caco-2 cells. Biosci Biotechnol Biochem. 2010;74(1):36-43. PMID: 20057149.

 

Napolitano M, Bravo E. Activation of protein kinase C by phorbol esters in human macrophages reduces the metabolism of modified LDL by down-regulation of scavenger receptor activity. Int J Biochem Cell Biol. 2003 Jul;35(7):1127-43. PMID: 12672483.

 

Mucha DR, Myers CL, Schaeffer RC Jr. Endothelial contraction and monolayer hyperpermeability are regulated by Src kinase. Am J Physiol Heart Circ Physiol. 2003 Mar;284(3):H994-H1002. PMID: 12456392.

 

Ren H, Chen S, Lu D. Herbimycin A enhances apoptotic effect of chemotherapeutic drugs on K562 cells. Chin Med J (Engl). 1998 Aug;111(8):678-81. PMID: 11245017.

 

Fukazawa H, Li PM, Yamamoto C, et al. Specific inhibition of cytoplasmic protein tyrosine kinases by herbimycin A in vitro. Biochem Pharmacol. 1991 Oct 9;42(9):1661-71. PMID: 1656993.

" Not dangerous goods.

LKT T0110 Taxane Standard Mixture 500 µl 762.4 Mixture of taxanes. ≥98% Ambient -20°C

LKT G1646 Geldanamycin 100 µg 27.2 HSP90 inhibitor. BRN 1633093 30562-34-6 ≥97% 560.64 C29H40N2O9 CC1CC(C(C(C=C(C(C(C=CC=C(C(=O)NC2=CC(=O)C(=C(C1)C2=O)OC)C)OC)OC(=O)N)C)C)O)OC Protect from light. Ambient -20°C Soluble in DMSO. "Rathore AP, Haystead T, Das PK, et al. Chikungunya virus nsP3 & nsP4 interacts with HSP-90 to promote virus replication: HSP-90 inhibitors reduce CHIKV infection and inflammation in vivo. Antiviral Res. 2014 Mar;103:7-16. PMID: 24388965.

 

Sun HH, Saheb-Al-Zamani M, Yan Y, et al. Geldanamycin accelerated peripheral nerve regeneration in comparison to FK-506 in vivo. Neuroscience. 2012 Oct 25;223:114-23. PMID: 22835622.

 

McNamara AV, Barclay M, Watson AJ, et al. Hsp90 inhibitors sensitise human colon cancer cells to topoisomerase I poisons by depletion of key anti-apoptotic and cell cycle checkpoint proteins. Biochem Pharmacol. 2012 Feb 1;83(3):355-67. PMID: 22138446.

" Not dangerous goods.

LKT G1646 Geldanamycin 5 x 100 µg 101.9 HSP90 inhibitor. BRN 1633093 30562-34-6 ≥97% 560.64 C29H40N2O9 CC1CC(C(C(C=C(C(C(C=CC=C(C(=O)NC2=CC(=O)C(=C(C1)C2=O)OC)C)OC)OC(=O)N)C)C)O)OC Protect from light. Ambient -20°C Soluble in DMSO. "Rathore AP, Haystead T, Das PK, et al. Chikungunya virus nsP3 & nsP4 interacts with HSP-90 to promote virus replication: HSP-90 inhibitors reduce CHIKV infection and inflammation in vivo. Antiviral Res. 2014 Mar;103:7-16. PMID: 24388965.

 

Sun HH, Saheb-Al-Zamani M, Yan Y, et al. Geldanamycin accelerated peripheral nerve regeneration in comparison to FK-506 in vivo. Neuroscience. 2012 Oct 25;223:114-23. PMID: 22835622.

 

McNamara AV, Barclay M, Watson AJ, et al. Hsp90 inhibitors sensitise human colon cancer cells to topoisomerase I poisons by depletion of key anti-apoptotic and cell cycle checkpoint proteins. Biochem Pharmacol. 2012 Feb 1;83(3):355-67. PMID: 22138446.

" Not dangerous goods.

LKT G1646 Geldanamycin 1 mg 129 HSP90 inhibitor. BRN 1633093 30562-34-6 ≥97% 560.64 C29H40N2O9 CC1CC(C(C(C=C(C(C(C=CC=C(C(=O)NC2=CC(=O)C(=C(C1)C2=O)OC)C)OC)OC(=O)N)C)C)O)OC Protect from light. Ambient -20°C Soluble in DMSO. "Rathore AP, Haystead T, Das PK, et al. Chikungunya virus nsP3 & nsP4 interacts with HSP-90 to promote virus replication: HSP-90 inhibitors reduce CHIKV infection and inflammation in vivo. Antiviral Res. 2014 Mar;103:7-16. PMID: 24388965.

 

Sun HH, Saheb-Al-Zamani M, Yan Y, et al. Geldanamycin accelerated peripheral nerve regeneration in comparison to FK-506 in vivo. Neuroscience. 2012 Oct 25;223:114-23. PMID: 22835622.

 

McNamara AV, Barclay M, Watson AJ, et al. Hsp90 inhibitors sensitise human colon cancer cells to topoisomerase I poisons by depletion of key anti-apoptotic and cell cycle checkpoint proteins. Biochem Pharmacol. 2012 Feb 1;83(3):355-67. PMID: 22138446.

" Not dangerous goods.

LKT R2810 Recombinant Multi-epitope Chimeric HIV Antigen 1 100 µg 681.7 Recombinant HIV-1 multi-epitope chimeric antigen. ≥95% Ambient -20°C

LKT R2810 Recombinant Multi-epitope Chimeric HIV Antigen 1 1 mg 2021.6 Recombinant HIV-1 multi-epitope chimeric antigen. ≥95% Ambient -20°C

LKT R2811 Recombinant HIV-1 gp-41 100 µg 450.6 Recombinant HIV glycoprotein antigen fragment. ≥95% Ambient -20°C

LKT R2811 Recombinant HIV-1 gp-41 1 mg 1328.5 Recombinant HIV glycoprotein antigen fragment. ≥95% Ambient -20°C

LKT R2812 Recombinant HIV-1 gp-120 100 µg 450.6 Recombinant HIV glycoprotein antigen fragment. ≥95% Ambient -20°C

LKT R2812 Recombinant HIV-1 gp-120 1 mg 1328.5 Recombinant HIV glycoprotein antigen fragment. ≥95% Ambient -20°C

LKT R2814 Recombinant HIV-1 p31 100 µg 365.7 Recombinant HIV antigen fragment. ≥95% Ambient -20°C

LKT R2814 Recombinant HIV-1 p31 1 mg 1078.2 Recombinant HIV antigen fragment. ≥95% Ambient -20°C

LKT R2711 Recombinant HCV-Core Antigens 100 µg 346.5 Recombinant HIV core protein antigen fragment. ≥95% Ambient -20°C

LKT R2711 Recombinant HCV-Core Antigens 1 mg 808.5 Recombinant HIV core protein antigen fragment. ≥95% Ambient -20°C

LKT R2712 Recombinant HCV-NS3 Antigens 100 µg 346.5 Recombinant HCV antigen fragment. ≥95% Ambient -20°C

LKT R2712 Recombinant HCV-NS3 Antigens 1 mg 808.5 Recombinant HCV antigen fragment. ≥95% Ambient -20°C

LKT R2713 Recombinant HCV-NS4 Antigens 100 µg 346.5 Recombinant HCV antigen fragment. ≥95% Ambient -20°C

LKT R2713 Recombinant HCV-NS4 Antigens 1 mg 808.5 Recombinant HCV antigen fragment. ≥95% Ambient -20°C

LKT R2714 Recombinant HCV-NS5 Antigens 100 µg 346.5 Recombinant HCV antigen fragment. ≥95% Ambient -20°C

LKT R2714 Recombinant HCV-NS5 Antigens 1 mg 808.5 Recombinant HCV antigen fragment. ≥95% Ambient -20°C

LKT R2815 Recombinant HIV-1 "0" group consensus 100 µg 577.6 Recombinant HIV-1 antigen fragment. ≥95% Ambient -20°C

LKT R2815 Recombinant HIV-1 "0" group consensus 1 mg 1617.2 Recombinant HIV-1 antigen fragment. ≥95% Ambient -20°C

LKT R2816 Recombinant HIV-2 gp36 100 µg 450.6 Recombinant HIV-1 glycoprotein antigen fragment. ≥95% Ambient -20°C

LKT R2816 Recombinant HIV-2 gp36 1 mg 1328.5 Recombinant HIV-1 glycoprotein antigen fragment. ≥95% Ambient -20°C

LKT R2710 Recombinant Multi-epitope Chimeric HCV Antigen 100 µg 346.5 Recombinant Multi-epitope Chimeric HCV antigen. ≥95% "Stored desiccated

below 0C" Ambient -20°C "The lyophilized protein is very soluble in distilled water and do not use solvents containing

potassium ion in sequential operation."

LKT R2710 Recombinant Multi-epitope Chimeric HCV Antigen 1 mg 808.5 Recombinant Multi-epitope Chimeric HCV antigen. ≥95% "Stored desiccated

below 0C" Ambient -20°C "The lyophilized protein is very soluble in distilled water and do not use solvents containing

potassium ion in sequential operation."

LKT R3010 Recombinant Tp-chimeric protein 100 µg 415.8 Recombinant chimeric protein containing Treponema pallidum fragments. ≥95% Ambient -20°C

LKT R3010 Recombinant Tp-chimeric protein 1 mg 1212.9 Recombinant chimeric protein containing Treponema pallidum fragments. ≥95% Ambient -20°C

LKT R3011 Recombinant TpN 15 protein 100 µg 415.8 Recombinant protein containing Treponema pallidum fragments. ≥95% Ambient -20°C

LKT R3011 Recombinant TpN 15 protein 1 mg 1212.9 Recombinant protein containing Treponema pallidum fragments. ≥95% Ambient -20°C

LKT R3012 Recombinant TpN 17 protein 100 µg 415.8 Recombinant protein containing Treponema pallidum fragments. ≥95% Ambient -20°C

LKT R3012 Recombinant TpN 17 protein 1 mg 1212.9 Recombinant protein containing Treponema pallidum fragments. ≥95% Ambient -20°C

LKT R3013 Recombinant TpN 44.50 protein 100 µg 415.8 Recombinant protein containing Treponema pallidum fragments. ≥95% Ambient -20°C

LKT R3013 Recombinant TpN 44.50 protein 1 mg 1212.9 Recombinant protein containing Treponema pallidum fragments. ≥95% Ambient -20°C

LKT R3014 Recombinant TpN 47 protein 100 µg 415.8 Recombinant protein containing Treponema pallidum fragments. ≥95% Ambient -20°C

LKT R3014 Recombinant TpN 47 protein 1 mg 1212.9 Recombinant protein containing Treponema pallidum fragments. ≥95% Ambient -20°C

LKT C8500 CV-65 100 µg 200 1,8-Diaza-anthracene-tetrone; JNK and ERK5 inhibitor. ≥60% 270.24 C13H7N2O4 Ambient -20°C Pipaón C, Gutierrez P, Montero JC, et al. Mitogen-activated protein kinase routes as targets in the action of diaza-anthracene compounds with a potent growth-inhibitory effect on cancer cells. Mol Cancer Ther. 2002 Aug;1(10):811-9. PMID: 12492114. Not dangerous goods.

LKT C8500 CV-65 1 mg 600 1,8-Diaza-anthracene-tetrone; JNK and ERK5 inhibitor. ≥60% 270.24 C13H7N2O4 Ambient -20°C Pipaón C, Gutierrez P, Montero JC, et al. Mitogen-activated protein kinase routes as targets in the action of diaza-anthracene compounds with a potent growth-inhibitory effect on cancer cells. Mol Cancer Ther. 2002 Aug;1(10):811-9. PMID: 12492114. Not dangerous goods.

LKT C8501 CV-66 100 µg 200 1,8-Diaza-anthracene-tetrone; JNK and ERK5 inhibitor. Diazaanthraquinone N-oxide ≥95% 270.24 C14H10N2O4 Ambient -20°C Pipaón C, Gutierrez P, Montero JC, et al. Mitogen-activated protein kinase routes as targets in the action of diaza-anthracene compounds with a potent growth-inhibitory effect on cancer cells. Mol Cancer Ther. 2002 Aug;1(10):811-9. PMID: 12492114. Not dangerous goods.

LKT C8501 CV-66 1 mg 600 1,8-Diaza-anthracene-tetrone; JNK and ERK5 inhibitor. Diazaanthraquinone N-oxide ≥95% 270.24 C14H10N2O4 Ambient -20°C Pipaón C, Gutierrez P, Montero JC, et al. Mitogen-activated protein kinase routes as targets in the action of diaza-anthracene compounds with a potent growth-inhibitory effect on cancer cells. Mol Cancer Ther. 2002 Aug;1(10):811-9. PMID: 12492114. Not dangerous goods.

LKT K1653 Kendomycin 100 µg 224.7 Macrolide; ET antagonist, proteasome inhibitor. (−)-TAN 2162 183202-73-5 ≥98% 486.64 C29H42O6 CC1CCC2C(C(C(C(O2)C3=C(C(=O)C(=C4C3=CC(O4)(C(CC(CC(=C1)C)C)C)O)C)O)C)O)C Ambient -20°C Soluble in DMSO or methanol. "Janssen CO, Lim S, Lo EP, et al. Interaction of kendomycin and semi-synthetic analogues with the anti-apoptotic protein Bcl-xl. Bioorg Med Chem Lett. 2008 Nov 1;18(21):5771-3. PMID: 18845435.

 

Elnakady YA, Rohde M, Sasse F, et al.  Evidence for the mode of action of the highly cytotoxic Streptomyces polyketide kendomycin. Chembiochem. 2007 Jul 23;8(11):1261-72. PMID: 17592829.

" Not dangerous goods.

LKT K1653 Kendomycin 500 µg 674.1 Macrolide; ET antagonist, proteasome inhibitor. (−)-TAN 2162 183202-73-5 ≥98% 486.64 C29H42O6 CC1CCC2C(C(C(C(O2)C3=C(C(=O)C(=C4C3=CC(O4)(C(CC(CC(=C1)C)C)C)O)C)O)C)O)C Ambient -20°C Soluble in DMSO or methanol. "Janssen CO, Lim S, Lo EP, et al. Interaction of kendomycin and semi-synthetic analogues with the anti-apoptotic protein Bcl-xl. Bioorg Med Chem Lett. 2008 Nov 1;18(21):5771-3. PMID: 18845435.

 

Elnakady YA, Rohde M, Sasse F, et al.  Evidence for the mode of action of the highly cytotoxic Streptomyces polyketide kendomycin. Chembiochem. 2007 Jul 23;8(11):1261-72. PMID: 17592829.

" Not dangerous goods.

LKT L1761 Leptomycin B 5 µg 47.6 Polyketide; CRM1 inhibitor. "19-(3,6-dihydro-3-methyl-6-oxo-2H-pyran-2-yl)-17-ethyl-6-hydroxy-3,5,7,9,11,15-hexamethyl-8-oxo- 2,10,12,16,18-Nonadecapentaenoic acid

" LMB; Elactocin, CI-940, CL-1957A, NSC-364372, PD-114720. 87081-35-4 ≥98% 540.74 C33H48O6 CCC(=CC(C)CC=CC(=CC(C)C(=O)C(C)C(C(C)CC(=CC(=O)O)C)O)C)C=CC1C(C=CC(=O)O1)C WARNING:  Small quantities of LepB are reported to be unstable when dried down into a film.  Thus, under no circumstances should the solvent be removed from solutions of LepB, because rapid decomposition may result. Ambient -20°C "Soluble in ethanol or methanol.

 

" "Sun Q, Carrasco YP, Hu Y, et al. Nuclear export inhibition through covalent conjugation and hydrolysis of Leptomycin B by CRM1. Proc Natl Acad Sci U S A. 2013 Jan 22;110(4):1303-8. PMID: 23297231.

 

Abkallo HM, Kawano H, Watanabe K, et al. A new cell-based reporter system for sensitive screening of nuclear export inhibitors. Drug Discov Ther. 2011 Dec;5(6):286-92. PMID: 22466439.

 

Lu C, Shao C, Cobos E, et al. Chemotherapeutic sensitization of leptomycin B resistant lung cancer cells by pretreatment with doxorubicin. PLoS One. 2012;7(3):e32895. PMID: 22412944.

 

Hamamoto T, Gunji S, Tsuji H, et al. Leptomycins A and B, new antifungal antibiotics. I. Taxonomy of the producing strain and their fermentation, purification and characterization. J Antibiot (Tokyo). 1983 Jun;36(6):639-45. PMID: 6874585.

" F, T, Xi "UN number: 1170     Class:  3     Packing group:  II

Proper shipping name:  Ethanol solution

Reportable Quantitiy (RQ):  7150 lbs.     Poison Inhalation Hazard:  No"

LKT R1985 Reveromycin A 100 µg 388.6 Isoleucyl-tRNA synthase inhibitor, osteoclast protein synthesis inhibitor. "Butanedioic acid, mono(3-butyl-8-(9-carboxy-6- hydroxy-3,7-dimethyl-2,4,8-nonatrienyl)-2-(4-carboxy-3-methyl-1,3-butadienyl)-9-methyl-1,7-dioxaspiro(5.5)undec-3-yl) ester 

" 134615-37-5 ≥98% 660.79 C36H52O11 CCCCC1(CCC2(CCC(C(O2)CC=C(C)C=CC(C(C)C=CC(=O)O)O)C)OC1C=CC(=CC(=O)O)C)OC(=O)CCC(=O)O Ambient -20°C Soluble in DMF, DMSO, ethanol, ethyl acetate or methanol. "Yabumoto T, Miyazawa K, Tabuchi M, et al. Stabilization of tooth movement by administration of reveromycin A to osteoprotegerin-deficient knockout mice. Am J Orthod Dentofacial Orthop. 2013 Sep;144(3):368-80. PMID: 23992809.

 

Hiraoka K, Zenmyo M, Watari K, et al. Inhibition of bone and muscle metastases of lung cancer cells by a decrease in the number of monocytes/macrophages. Cancer Sci. 2008 Aug;99(8):1595-602. PMID: 18754872.

 

Woo JT, Kawatani M, Kato M, et al. Reveromycin A, an agent for osteoporosis, inhibits bone resorption by inducing apoptosis specifically in osteoclasts. Proc Natl Acad Sci U S A. 2006 Mar 21;103(12):4729-34. PMID: 16537392.

" Not dangerous goods.

LKT R1985 Reveromycin A 5 x 100 µg 1575.2 Isoleucyl-tRNA synthase inhibitor, osteoclast protein synthesis inhibitor. "Butanedioic acid, mono(3-butyl-8-(9-carboxy-6- hydroxy-3,7-dimethyl-2,4,8-nonatrienyl)-2-(4-carboxy-3-methyl-1,3-butadienyl)-9-methyl-1,7-dioxaspiro(5.5)undec-3-yl) ester 

" 134615-37-5 ≥98% 660.79 C36H52O11 CCCCC1(CCC2(CCC(C(O2)CC=C(C)C=CC(C(C)C=CC(=O)O)O)C)OC1C=CC(=CC(=O)O)C)OC(=O)CCC(=O)O Ambient -20°C Soluble in DMF, DMSO, ethanol, ethyl acetate or methanol. "Yabumoto T, Miyazawa K, Tabuchi M, et al. Stabilization of tooth movement by administration of reveromycin A to osteoprotegerin-deficient knockout mice. Am J Orthod Dentofacial Orthop. 2013 Sep;144(3):368-80. PMID: 23992809.

 

Hiraoka K, Zenmyo M, Watari K, et al. Inhibition of bone and muscle metastases of lung cancer cells by a decrease in the number of monocytes/macrophages. Cancer Sci. 2008 Aug;99(8):1595-602. PMID: 18754872.

 

Woo JT, Kawatani M, Kato M, et al. Reveromycin A, an agent for osteoporosis, inhibits bone resorption by inducing apoptosis specifically in osteoclasts. Proc Natl Acad Sci U S A. 2006 Mar 21;103(12):4729-34. PMID: 16537392.

" Not dangerous goods.

LKT C8502 CV-70 100 µg 115.6 1,8-Diaza-anthracene-tetrone; JNK and ERK5 inhibitor. ≥90% 298.29 C16H14N2O4 Ambient -20°C Pipaón C, Gutierrez P, Montero JC, et al. Mitogen-activated protein kinase routes as targets in the action of diaza-anthracene compounds with a potent growth-inhibitory effect on cancer cells. Mol Cancer Ther. 2002 Aug;1(10):811-9. PMID: 12492114. Not dangerous goods.

LKT C8502 CV-70 1 mg 577.8 1,8-Diaza-anthracene-tetrone; JNK and ERK5 inhibitor. ≥90% 298.29 C16H14N2O4 Ambient -20°C Pipaón C, Gutierrez P, Montero JC, et al. Mitogen-activated protein kinase routes as targets in the action of diaza-anthracene compounds with a potent growth-inhibitory effect on cancer cells. Mol Cancer Ther. 2002 Aug;1(10):811-9. PMID: 12492114. Not dangerous goods.

LKT AN118 Antineoplastics 1 kit 307.7 Dry Ice -80°C

LKT AN119 Antineoplastics 1 kit 264.5 Dry Ice -80°C

LKT AN120 Antineoplastics 1 kit 791.7 Dry Ice -80°C

LKT AM121 Antimicrobial 1 kit 298 Dry Ice -80°C

LKT AM122 Antimicrobial 1 kit 167 Dry Ice -80°C

LKT AM123 Antimicrobial 1 kit 163.2 Dry Ice -80°C

LKT AM124 Antimicrobial 1 kit 391.9 Dry Ice -80°C

LKT AM125 Antimicrobial 1 kit 153.8 Dry Ice -80°C

LKT AM126 Antimicrobial 1 kit 240.1 Dry Ice -80°C

LKT AP119 Apoptosis 1 kit 510 Dry Ice -80°C

LKT AP120 Apoptosis 1 kit 313.3 Dry Ice -80°C

LKT AP121 Apoptosis 1 kit 219.6 Dry Ice -80°C

LKT AP122 Apoptosis 1 kit 937.5 Dry Ice -80°C

LKT AP123 Apoptosis 1 kit 294.3 Dry Ice -80°C

LKT NP124 Natural Products 1 kit 1241.2 Dry Ice -80°C

LKT NP125 Natural Products 1 kit 204.3 Dry Ice -80°C

LKT NP126 Natural Products 1 kit 365.7 Dry Ice -80°C

LKT NP127 Natural Products 1 kit 956.2 Dry Ice -80°C

LKT NA105 NSAIDs 1 kit 153.8 Dry Ice -80°C

LKT ST111 Signal Transduction 1 kit 178.1 Dry Ice -80°C

LKT ST112 Signal Transduction 1 kit 215.6 Dry Ice -80°C

LKT ST113 Signal Transduction 1 kit 384.3 Dry Ice -80°C

LKT ST114 Signal Transduction 1 kit 380.6 Dry Ice -80°C

LKT K0021 K252a 100 µg 71.9 Staurosporine analog; PKC inhibitor, TrkA/B antagonist. SF 2370 99533-80-9 ≥98% 467.48 C27H21N3O5 CC12C(CC(O1)N3C4=CC=CC=C4C5=C6C(=C7C8=CC=CC=C8N2C7=C53)CNC6=O)(C(=O)OC)O Ambient 4°C "Readily soluble in chloroform, acetonitrile, acetone, dioxane, tetrahydrofuran, pyridine;

soluble in ethanol, methanol, 1-propanol, ethyl acetate and n-butanol;

insoluble in water, 2-propanol" "El-Hashim AZ, Jaffal SM, Al-Rashidi FT, et al. Nerve growth factor enhances cough via a central mechanism of action. Pharmacol Res. 2013 Aug;74:68-77. PMID: 23742790.

 

Cardenas-Aguayo Mdel C, Kazim SF, Grundke-Iqbal I, et al. Neurogenic and neurotrophic effects of BDNF peptides in mouse hippocampal primary neuronal cell cultures. PLoS One. 2013;8(1):e53596. PMID: 23320097.

 

Sugiya H, Putney JW Jr. Protein kinase C-dependent and -independent mechanisms regulating the parotid substance P receptor as revealed by differential effects of protein kinase C inhibitors. Biochem J. 1988 Dec 1;256(2):677-80. PMID: 2464997.

 

Hashimoto S. K-252a, a potent protein kinase inhibitor, blocks nerve growth factor-induced neurite outgrowth and changes in the phosphorylation of proteins in PC12h cells. J Cell Biol. 1988 Oct;107(4):1531-9. PMID: 2844830.

" Xi Not dangerous goods.

LKT K0021 K252a 1 mg 285.4 Staurosporine analog; PKC inhibitor, TrkA/B antagonist. SF 2370 99533-80-9 ≥98% 467.48 C27H21N3O5 CC12C(CC(O1)N3C4=CC=CC=C4C5=C6C(=C7C8=CC=CC=C8N2C7=C53)CNC6=O)(C(=O)OC)O Ambient 4°C "Readily soluble in chloroform, acetonitrile, acetone, dioxane, tetrahydrofuran, pyridine;

soluble in ethanol, methanol, 1-propanol, ethyl acetate and n-butanol;

insoluble in water, 2-propanol" "El-Hashim AZ, Jaffal SM, Al-Rashidi FT, et al. Nerve growth factor enhances cough via a central mechanism of action. Pharmacol Res. 2013 Aug;74:68-77. PMID: 23742790.

 

Cardenas-Aguayo Mdel C, Kazim SF, Grundke-Iqbal I, et al. Neurogenic and neurotrophic effects of BDNF peptides in mouse hippocampal primary neuronal cell cultures. PLoS One. 2013;8(1):e53596. PMID: 23320097.

 

Sugiya H, Putney JW Jr. Protein kinase C-dependent and -independent mechanisms regulating the parotid substance P receptor as revealed by differential effects of protein kinase C inhibitors. Biochem J. 1988 Dec 1;256(2):677-80. PMID: 2464997.

 

Hashimoto S. K-252a, a potent protein kinase inhibitor, blocks nerve growth factor-induced neurite outgrowth and changes in the phosphorylation of proteins in PC12h cells. J Cell Biol. 1988 Oct;107(4):1531-9. PMID: 2844830.

" Xi Not dangerous goods.

LKT K0022 K252b 100 µg 129.5 Staurosporine analog; PKC inhibitor. Protein Kinase Inhibitor K-252B 99570-78-2 ≥98% 453.13 C26H16N3O5 CC12C(CC(O1)N3C4=CC=CC=C4C5=C6C(=C7C8=CC=CC=C8N2C7=C53)CNC6=O)(C(=O)O)O Ambient 4°C DMSO or Methanol "Lecht S, Arien-Zakay H, Kohan M, et al. Angiostatic effects of K252a, a Trk inhibitor, in murine brain capillary endothelial cells. Mol Cell Biochem. 2010 Jun;339(1-2):201-13. PMID: 20148355.

 

Okada M, Hojo Y, Ikeda U, et al. Interaction between monocytes and vascular smooth muscle cells induces expression of hepatocyte growth factor. J Hypertens. 2000 Dec;18(12):1825-31. PMID: 11132607.

 

Teshima R, Saito Y, Ikebuchi H, et al. Effect of an ectokinase inhibitor, K252b, on degranulation and Ca2+ signals of RBL-2H3 cells and human basophils. J Immunol. 1997 Jul 15;159(2):964-9. PMID: 9218617.

 

Hogan MV, Pawlowska Z, Yang HA, et al. Surface phosphorylation by ecto-protein kinase C in brain neurons: a target for Alzheimer's beta-amyloid peptides. J Neurochem. 1995 Nov;65(5):2022-30. PMID: 7595486.

 

Lagoo A, Tseng CK, Sell S. Molecular signals in B cell activation. II. IL-2-mediated signals are required in late G1 for transition to S phase after ionomycin and PMA treatment. Cell Immunol. 1990 May;127(2):497-505. PMID: 2328536.

" Xi Not dangerous goods.

LKT K0022 K252b 1 mg 968.2 Staurosporine analog; PKC inhibitor. Protein Kinase Inhibitor K-252B 99570-78-2 ≥98% 453.13 C26H16N3O5 CC12C(CC(O1)N3C4=CC=CC=C4C5=C6C(=C7C8=CC=CC=C8N2C7=C53)CNC6=O)(C(=O)O)O Ambient 4°C DMSO or Methanol "Lecht S, Arien-Zakay H, Kohan M, et al. Angiostatic effects of K252a, a Trk inhibitor, in murine brain capillary endothelial cells. Mol Cell Biochem. 2010 Jun;339(1-2):201-13. PMID: 20148355.

 

Okada M, Hojo Y, Ikeda U, et al. Interaction between monocytes and vascular smooth muscle cells induces expression of hepatocyte growth factor. J Hypertens. 2000 Dec;18(12):1825-31. PMID: 11132607.

 

Teshima R, Saito Y, Ikebuchi H, et al. Effect of an ectokinase inhibitor, K252b, on degranulation and Ca2+ signals of RBL-2H3 cells and human basophils. J Immunol. 1997 Jul 15;159(2):964-9. PMID: 9218617.

 

Hogan MV, Pawlowska Z, Yang HA, et al. Surface phosphorylation by ecto-protein kinase C in brain neurons: a target for Alzheimer's beta-amyloid peptides. J Neurochem. 1995 Nov;65(5):2022-30. PMID: 7595486.

 

Lagoo A, Tseng CK, Sell S. Molecular signals in B cell activation. II. IL-2-mediated signals are required in late G1 for transition to S phase after ionomycin and PMA treatment. Cell Immunol. 1990 May;127(2):497-505. PMID: 2328536.

" Xi Not dangerous goods.

LKT K7600 KT5720 100 µg 170.3 PKA and PDK1 inhibitor, HCN channel blocker, potential GSK3, MEK, MSK1, PKB inhibitor. 108068-98-0 ≥98% 537.23 C32H31N3O5 CCCCCCOC(=O)C1(CC2N3C4=CC=CC=C4C5=C6C(=C7C8=CC=CC=C8N(C7=C53)C1(O2)C)CNC6=O)O Ambient 4°C Soluble in methanol, DMSO "Iwase K, Ishihara A, Yoshimura S, et al. The secretogranin II gene is a signal integrator of glutamate and dopamine inputs. J Neurochem. 2014 Jan;128(2):233-45. PMID: 24111984.

 

Hoffman MS, Mitchell GS. Spinal 5-HT7 receptors and protein kinase A constrain intermittent hypoxia-induced phrenic long-term facilitation. Neuroscience. 2013 Oct 10;250:632-43. PMID: 23850591.

 

Cheng Q, Zhou Y. Novel role of KT5720 on regulating hyperpolarization-activated cyclic nucleotide-gated channel activity and dorsal root ganglion neuron excitability. DNA Cell Biol. 2013 Jun;32(6):320-8. PMID: 23713946.

" Not dangerous goods.

LKT K7600 KT5720 1 mg 1278.6 PKA and PDK1 inhibitor, HCN channel blocker, potential GSK3, MEK, MSK1, PKB inhibitor. 108068-98-0 ≥98% 537.23 C32H31N3O5 CCCCCCOC(=O)C1(CC2N3C4=CC=CC=C4C5=C6C(=C7C8=CC=CC=C8N(C7=C53)C1(O2)C)CNC6=O)O Ambient 4°C Soluble in methanol, DMSO "Iwase K, Ishihara A, Yoshimura S, et al. The secretogranin II gene is a signal integrator of glutamate and dopamine inputs. J Neurochem. 2014 Jan;128(2):233-45. PMID: 24111984.

 

Hoffman MS, Mitchell GS. Spinal 5-HT7 receptors and protein kinase A constrain intermittent hypoxia-induced phrenic long-term facilitation. Neuroscience. 2013 Oct 10;250:632-43. PMID: 23850591.

 

Cheng Q, Zhou Y. Novel role of KT5720 on regulating hyperpolarization-activated cyclic nucleotide-gated channel activity and dorsal root ganglion neuron excitability. DNA Cell Biol. 2013 Jun;32(6):320-8. PMID: 23713946.

" Not dangerous goods.

LKT K7602 KT5823 100 µg 170.3 PKG inhibitor. 126643-37-6 ≥98% 495.5 C28H23N3O5 CC12C(CC(O1)N3C4=CC=CC=C4C5=C6C(=C7C8=CC=CC=C8N2C7=C53)CN(C6=O)C)(C(=O)OC)OC Ambient 4°C DMSO, Ethyl Acetate "Salloum FN, Das A, Samidurai A, et al. Cinaciguat, a novel activator of soluble guanylate cyclase, protects against ischemia/reperfusion injury: role of hydrogen sulfide. Am J Physiol Heart Circ Physiol. 2012 Mar 15;302(6):H1347-54. PMID: 22268103.

 

Moreno H, Vega-Saenz de Miera E, Nadal MS, et al. Modulation of Kv3 potassium channels expressed in CHO cells by a nitric oxide-activated phosphatase. J Physiol. 2001 Feb 1;530(Pt 3):345-58. PMID: 11281123.

" Not dangerous goods.

LKT K7602 KT5823 1 mg 1278.6 PKG inhibitor. 126643-37-6 ≥98% 495.5 C28H23N3O5 CC12C(CC(O1)N3C4=CC=CC=C4C5=C6C(=C7C8=CC=CC=C8N2C7=C53)CN(C6=O)C)(C(=O)OC)OC Ambient 4°C DMSO, Ethyl Acetate "Salloum FN, Das A, Samidurai A, et al. Cinaciguat, a novel activator of soluble guanylate cyclase, protects against ischemia/reperfusion injury: role of hydrogen sulfide. Am J Physiol Heart Circ Physiol. 2012 Mar 15;302(6):H1347-54. PMID: 22268103.

 

Moreno H, Vega-Saenz de Miera E, Nadal MS, et al. Modulation of Kv3 potassium channels expressed in CHO cells by a nitric oxide-activated phosphatase. J Physiol. 2001 Feb 1;530(Pt 3):345-58. PMID: 11281123.

" Not dangerous goods.

LKT C0351 Carprofen 1 g 65.6 NSAID; COX-2 inhibitor. 6-Chloro-α-methyl-9H-carbazole-2-acetic acid Imadyl; Rimadyl 53716-49-7 ≥98% 273.71 C15H12ClNO2 CC(C1=CC2=C(C=C1)C3=C(N2)C=CC(=C3)Cl)C(=O)O Ambient Ambient Soluble in ethanol. Insoluble in water. Lees P, Delatour P, Foster AP, et al. Evaluation of carprofen in calves using a tissue cage model of inflammation. Br Vet J. 1996 Mar;152(2):199-211. PMID: 8680842. T "UN number: 2811     Class 6.1     Packing Group:  III

Proper shipping name:  Toxic solids, organic, n.o.s. (Carprofen)

Marine pollutant:  No.  Poison Inhalation Hazard:  No"

LKT C0351 Carprofen 5 g 234.5 NSAID; COX-2 inhibitor. 6-Chloro-α-methyl-9H-carbazole-2-acetic acid Imadyl; Rimadyl 53716-49-7 ≥98% 273.71 C15H12ClNO2 CC(C1=CC2=C(C=C1)C3=C(N2)C=CC(=C3)Cl)C(=O)O Ambient Ambient Soluble in ethanol. Insoluble in water. Lees P, Delatour P, Foster AP, et al. Evaluation of carprofen in calves using a tissue cage model of inflammation. Br Vet J. 1996 Mar;152(2):199-211. PMID: 8680842. T "UN number: 2811     Class 6.1     Packing Group:  III

Proper shipping name:  Toxic solids, organic, n.o.s. (Carprofen)

Marine pollutant:  No.  Poison Inhalation Hazard:  No"

LKT V3479 Vitamin K3 10 g 28.7 Synthetic analog of 1,4-naphthoquinone, precursor in synthesis of vitamin K2; microtubule polymerization inhibitor, MAO-A/B inhibitor. 2-Methyl-1,4-naphthalenedione Menadione; Menaphthone; Kappaxin; Kayquinone; Thyloquinone, 2-Methyl-1,4-naphthoquinone 58-27-5 ≥98% 172.18 C11H8O2 CC1=CC(=O)C2=CC=CC=C2C1=O Protect from light. Ambient -20°C Insoluble in water. Soluble  in ethanol (16 mg/mL) and benzene. Slightly soluble in chloroform and carbon tetrachloride. "Kim YJ, Shin YK, Sohn DS, et al. Menadione induces the formation of reactive oxygen species and depletion of GSH-mediated apoptosis and inhibits the FAK-mediated cell invasion. Naunyn Schmiedebergs Arch Pharmacol. 2014 Sep;387(9):799-809. PMID: 24879465.

 

Coelho Cerqueira E, Netz PA, et al. Molecular insights into human monoamine oxidase (MAO) inhibition by 1,4-naphthoquinone: evidences for menadione (vitamin K3) acting as a competitive and reversible inhibitor of MAO. Bioorg Med Chem. 2011 Dec 15;19(24):7416-24. PMID: 22071524.

 

Kawamura F, Nakanishi M, Hirashima N. Effects of menadione, a reactive oxygen generator, on leukotriene secretion from RBL-2H3 cells. Biol Pharm Bull. 2010;33(5):881-5. PMID: 20460770.

 

Acharya BR, Choudhury D, Das A, et al. Vitamin K3 disrupts the microtubule networks by binding to tubulin: a novel mechanism of its antiproliferative activity. Biochemistry. 2009 Jul 28;48(29):6963-74. PMID: 19527023.

" Xn, Xi Not dangerous goods.

LKT V3479 Vitamin K3 25 g 46.2 Synthetic analog of 1,4-naphthoquinone, precursor in synthesis of vitamin K2; microtubule polymerization inhibitor, MAO-A/B inhibitor. 2-Methyl-1,4-naphthalenedione Menadione; Menaphthone; Kappaxin; Kayquinone; Thyloquinone, 2-Methyl-1,4-naphthoquinone 58-27-5 ≥98% 172.18 C11H8O2 CC1=CC(=O)C2=CC=CC=C2C1=O Protect from light. Ambient -20°C Insoluble in water. Soluble  in ethanol (16 mg/mL) and benzene. Slightly soluble in chloroform and carbon tetrachloride. "Kim YJ, Shin YK, Sohn DS, et al. Menadione induces the formation of reactive oxygen species and depletion of GSH-mediated apoptosis and inhibits the FAK-mediated cell invasion. Naunyn Schmiedebergs Arch Pharmacol. 2014 Sep;387(9):799-809. PMID: 24879465.

 

Coelho Cerqueira E, Netz PA, et al. Molecular insights into human monoamine oxidase (MAO) inhibition by 1,4-naphthoquinone: evidences for menadione (vitamin K3) acting as a competitive and reversible inhibitor of MAO. Bioorg Med Chem. 2011 Dec 15;19(24):7416-24. PMID: 22071524.

 

Kawamura F, Nakanishi M, Hirashima N. Effects of menadione, a reactive oxygen generator, on leukotriene secretion from RBL-2H3 cells. Biol Pharm Bull. 2010;33(5):881-5. PMID: 20460770.

 

Acharya BR, Choudhury D, Das A, et al. Vitamin K3 disrupts the microtubule networks by binding to tubulin: a novel mechanism of its antiproliferative activity. Biochemistry. 2009 Jul 28;48(29):6963-74. PMID: 19527023.

" Xn, Xi Not dangerous goods.

LKT V3476 Vitamin D2 1 g 33.9 Vitamin D prodrug produced by fungi and alfalfa. (3β,5Z,7E,22E)-9,10-Secoergosta-5,7-10(19),22-tetra- en-3-ol Calciferol; Ergocalciferol; Viosterol; Condol; Deltalin; Diactol; Ergorone; Infron; Mulsiferol; Ostelin; Radsterin 50-14-6 ≥91% 396.65 C28H44O CC(C)C(C)C=CC(C)C1CCC2C1(CCCC2=CC=C3CC(CCC3=C)O)C Ambient -20°C Soluble in organic solvents. Insoluble in water. "Bikle DD. Vitamin D metabolism, mechanism of action, and clinical applications. Chem Biol. 2014 Mar 20;21(3):319-29. PMID: 24529992.

 

Chen WJ, Huang YT, Wu ML, et al. Induction of apoptosis by vitamin D2, ergocalciferol, via reactive oxygen species generation, glutathione depletion, and caspase activation in human leukemia Cells. J Agric Food Chem. 2008 May 14;56(9):2996-3005. PMID: 18386902.

 

Zinser GM, Tribble E, Valrance M, et al. 1,24(S)-dihydroxyvitamin D2, an endogenous vitamin D2 metabolite, inhibits growth of breast cancer cells and tumors. Anticancer Res. 2005 Jan-Feb;25(1A):235-41. PMID: 15816543.

" Xn, T, T+ Carc. "UN number: 2811     Class: 6.1     Packing Group: II

Proper shipping name: Toxic solid, organic, n.o.s. (Vitamin D2)"

LKT V3476 Vitamin D2 5 g 122.3 Vitamin D prodrug produced by fungi and alfalfa. (3β,5Z,7E,22E)-9,10-Secoergosta-5,7-10(19),22-tetra- en-3-ol Calciferol; Ergocalciferol; Viosterol; Condol; Deltalin; Diactol; Ergorone; Infron; Mulsiferol; Ostelin; Radsterin 50-14-6 ≥91% 396.65 C28H44O CC(C)C(C)C=CC(C)C1CCC2C1(CCCC2=CC=C3CC(CCC3=C)O)C Ambient -20°C Soluble in organic solvents. Insoluble in water. "Bikle DD. Vitamin D metabolism, mechanism of action, and clinical applications. Chem Biol. 2014 Mar 20;21(3):319-29. PMID: 24529992.

 

Chen WJ, Huang YT, Wu ML, et al. Induction of apoptosis by vitamin D2, ergocalciferol, via reactive oxygen species generation, glutathione depletion, and caspase activation in human leukemia Cells. J Agric Food Chem. 2008 May 14;56(9):2996-3005. PMID: 18386902.

 

Zinser GM, Tribble E, Valrance M, et al. 1,24(S)-dihydroxyvitamin D2, an endogenous vitamin D2 metabolite, inhibits growth of breast cancer cells and tumors. Anticancer Res. 2005 Jan-Feb;25(1A):235-41. PMID: 15816543.

" Xn, T, T+ Carc. "UN number: 2811     Class: 6.1     Packing Group: II

Proper shipping name: Toxic solid, organic, n.o.s. (Vitamin D2)"

LKT V3454 Vinleurosine Sulfate 10 mg 80.4 Alkaloid found in Catharanthus. 54081-68-4 ≥95% 907.04 C46H56N4O9 H2O4S CCC12CN3CCC4=C(C(CC(C3)C1O2)(C5=C(C=C6C(=C5)C78CCN9C7C(C=CC9)(C(C(C8N6C)(C(=O)OC)O)OC(=O)C)CC)OC)C(=O)OC)NC1=CC=CC=C41.OS(=O)(=O)O Ambient -20°C "Chen Q, Zhang W, Zhang Y, et al. Identification and quantification of active alkaloids in Catharanthus roseus by liquid chromatography-ion trap mass spectrometry. Food Chem. 2013 Aug 15;139(1-4):845-52. PMID: 23561180.

 

Fyfe MJ, Loftfield S, Goldman ID.  A reduction in energy-dependent amino acid transport by microtubular inhibitors in Ehrlich ascites tumor cells. J Cell Physiol. 1975 Oct;86(2 Pt 1):201-11. PMID: 1194361.

" Not dangerous goods.

LKT V3454 Vinleurosine Sulfate 25 mg 167.4 Alkaloid found in Catharanthus. 54081-68-4 ≥95% 907.04 C46H56N4O9 H2O4S CCC12CN3CCC4=C(C(CC(C3)C1O2)(C5=C(C=C6C(=C5)C78CCN9C7C(C=CC9)(C(C(C8N6C)(C(=O)OC)O)OC(=O)C)CC)OC)C(=O)OC)NC1=CC=CC=C41.OS(=O)(=O)O Ambient -20°C "Chen Q, Zhang W, Zhang Y, et al. Identification and quantification of active alkaloids in Catharanthus roseus by liquid chromatography-ion trap mass spectrometry. Food Chem. 2013 Aug 15;139(1-4):845-52. PMID: 23561180.

 

Fyfe MJ, Loftfield S, Goldman ID.  A reduction in energy-dependent amino acid transport by microtubular inhibitors in Ehrlich ascites tumor cells. J Cell Physiol. 1975 Oct;86(2 Pt 1):201-11. PMID: 1194361.

" Not dangerous goods.

LKT V3454 Vinleurosine Sulfate 100 mg 535.7 Alkaloid found in Catharanthus. 54081-68-4 ≥95% 907.04 C46H56N4O9 H2O4S CCC12CN3CCC4=C(C(CC(C3)C1O2)(C5=C(C=C6C(=C5)C78CCN9C7C(C=CC9)(C(C(C8N6C)(C(=O)OC)O)OC(=O)C)CC)OC)C(=O)OC)NC1=CC=CC=C41.OS(=O)(=O)O Ambient -20°C "Chen Q, Zhang W, Zhang Y, et al. Identification and quantification of active alkaloids in Catharanthus roseus by liquid chromatography-ion trap mass spectrometry. Food Chem. 2013 Aug 15;139(1-4):845-52. PMID: 23561180.

 

Fyfe MJ, Loftfield S, Goldman ID.  A reduction in energy-dependent amino acid transport by microtubular inhibitors in Ehrlich ascites tumor cells. J Cell Physiol. 1975 Oct;86(2 Pt 1):201-11. PMID: 1194361.

" Not dangerous goods.

LKT V3378 Vitamin B12 500 mg 74.8 Coenzyme, vitamin found in dairy, meat, eggs, fermented food, plays a role in cellular metabolism and fatty acid synthesis. Cyanocobalamin Cobalin; Bedoz; Cytobion; Vitarubin 68-19-9 ≥97% 1355.37 C63H88CoN14O14P CC1=CC2=C(C=C1C)N(C=N2)C3C(C(C(O3)CO)OP(=O)([O-])OC(C)CNC(=O)CCC4(C(C5C6(C(C(C(=C(C7=NC(=CC8=NC(=C(C4=N5)C)C(C8(C)C)CCC(=O)N)C(C7(C)CC(=O)N)CCC(=O)N)C)[N-]6)CCC(=O)N)(C)CC(=O)N)C)CC(=O)N)C)O.[C-]#N.[Co+3] Hygroscopic Ambient Ambient Soluble in alcohol and water. Insolubl in ether, chloroform and acetone. "Kumar N. Neurologic. Aspects of cobalamin (B12) deficiency. Handb Clin Neurol. 2014;120:915-26. PMID: 24365360.

 

Briani C, Dalla Torre C, Citton V, et al. Cobalamin deficiency: clinical picture and radiological findings. Nutrients. 2013 Nov 15;5(11):4521-39. PMID: 24248213.

 

Scott JM, Molloy AM. The discovery of vitamin B(12). Ann Nutr Metab. 2012;61(3):239-45. PMID: 23183296.

" None Not dangerous goods.

LKT V3378 Vitamin B12 1 g 111.7 Coenzyme, vitamin found in dairy, meat, eggs, fermented food, plays a role in cellular metabolism and fatty acid synthesis. Cyanocobalamin Cobalin; Bedoz; Cytobion; Vitarubin 68-19-9 ≥97% 1355.37 C63H88CoN14O14P CC1=CC2=C(C=C1C)N(C=N2)C3C(C(C(O3)CO)OP(=O)([O-])OC(C)CNC(=O)CCC4(C(C5C6(C(C(C(=C(C7=NC(=CC8=NC(=C(C4=N5)C)C(C8(C)C)CCC(=O)N)C(C7(C)CC(=O)N)CCC(=O)N)C)[N-]6)CCC(=O)N)(C)CC(=O)N)C)CC(=O)N)C)O.[C-]#N.[Co+3] Hygroscopic Ambient Ambient Soluble in alcohol and water. Insolubl in ether, chloroform and acetone. "Kumar N. Neurologic. Aspects of cobalamin (B12) deficiency. Handb Clin Neurol. 2014;120:915-26. PMID: 24365360.

 

Briani C, Dalla Torre C, Citton V, et al. Cobalamin deficiency: clinical picture and radiological findings. Nutrients. 2013 Nov 15;5(11):4521-39. PMID: 24248213.

 

Scott JM, Molloy AM. The discovery of vitamin B(12). Ann Nutr Metab. 2012;61(3):239-45. PMID: 23183296.

" None Not dangerous goods.

LKT V3378 Vitamin B12 5 g 276.6 Coenzyme, vitamin found in dairy, meat, eggs, fermented food, plays a role in cellular metabolism and fatty acid synthesis. Cyanocobalamin Cobalin; Bedoz; Cytobion; Vitarubin 68-19-9 ≥97% 1355.37 C63H88CoN14O14P CC1=CC2=C(C=C1C)N(C=N2)C3C(C(C(O3)CO)OP(=O)([O-])OC(C)CNC(=O)CCC4(C(C5C6(C(C(C(=C(C7=NC(=CC8=NC(=C(C4=N5)C)C(C8(C)C)CCC(=O)N)C(C7(C)CC(=O)N)CCC(=O)N)C)[N-]6)CCC(=O)N)(C)CC(=O)N)C)CC(=O)N)C)O.[C-]#N.[Co+3] Hygroscopic Ambient Ambient Soluble in alcohol and water. Insolubl in ether, chloroform and acetone. "Kumar N. Neurologic. Aspects of cobalamin (B12) deficiency. Handb Clin Neurol. 2014;120:915-26. PMID: 24365360.

 

Briani C, Dalla Torre C, Citton V, et al. Cobalamin deficiency: clinical picture and radiological findings. Nutrients. 2013 Nov 15;5(11):4521-39. PMID: 24248213.

 

Scott JM, Molloy AM. The discovery of vitamin B(12). Ann Nutr Metab. 2012;61(3):239-45. PMID: 23183296.

" None Not dangerous goods.

LKT V3360 Vasoactive Intestinal Peptide, guinea pig 0.5 mg 204.1 Endogenous peptide hormone, involved in enteric movement and hormone secretion; VPAC1/2 agonist. VIP, guinea pig ≥95% 3344.93 C147H239N43O42S2 Ambient -20°C "Hauk V, Azzam S, Calo G, et al. Vasoactive intestinal Peptide induces an immunosuppressant microenvironment in the maternal-fetal interface of non-obese diabetic mice and improves early pregnancy outcome. Am J Reprod Immunol. 2014 Feb;71(2):120-30. PMID: 24405265.

 

Fraccaroli L, Grasso E, Hauk V, et al. Contribution of Vasoactive Intestinal Peptide to Immune Homeostasis in Trophoblast-Maternal Leukocyte Interaction under LPS Stimulation. Neuroimmunomodulation. 2014;21(1):21-30. PMID: 24135863.

 

Mathioudakis A, Chatzimavridou-Grigoriadou V, Evangelopoulou E, et al. Vasoactive intestinal Peptide inhaled agonists: potential role in respiratory therapeutics. Hippokratia. 2013 Jan;17(1):12-6. PMID: 23935337.

" Not dangerous goods.

LKT V3360 Vasoactive Intestinal Peptide, guinea pig 1 mg 348 Endogenous peptide hormone, involved in enteric movement and hormone secretion; VPAC1/2 agonist. VIP, guinea pig ≥95% 3344.93 C147H239N43O42S2 Ambient -20°C "Hauk V, Azzam S, Calo G, et al. Vasoactive intestinal Peptide induces an immunosuppressant microenvironment in the maternal-fetal interface of non-obese diabetic mice and improves early pregnancy outcome. Am J Reprod Immunol. 2014 Feb;71(2):120-30. PMID: 24405265.

 

Fraccaroli L, Grasso E, Hauk V, et al. Contribution of Vasoactive Intestinal Peptide to Immune Homeostasis in Trophoblast-Maternal Leukocyte Interaction under LPS Stimulation. Neuroimmunomodulation. 2014;21(1):21-30. PMID: 24135863.

 

Mathioudakis A, Chatzimavridou-Grigoriadou V, Evangelopoulou E, et al. Vasoactive intestinal Peptide inhaled agonists: potential role in respiratory therapeutics. Hippokratia. 2013 Jan;17(1):12-6. PMID: 23935337.

" Not dangerous goods.

LKT V3360 Vasoactive Intestinal Peptide, guinea pig 2.5 mg 612.4 Endogenous peptide hormone, involved in enteric movement and hormone secretion; VPAC1/2 agonist. VIP, guinea pig ≥95% 3344.93 C147H239N43O42S2 Ambient -20°C "Hauk V, Azzam S, Calo G, et al. Vasoactive intestinal Peptide induces an immunosuppressant microenvironment in the maternal-fetal interface of non-obese diabetic mice and improves early pregnancy outcome. Am J Reprod Immunol. 2014 Feb;71(2):120-30. PMID: 24405265.

 

Fraccaroli L, Grasso E, Hauk V, et al. Contribution of Vasoactive Intestinal Peptide to Immune Homeostasis in Trophoblast-Maternal Leukocyte Interaction under LPS Stimulation. Neuroimmunomodulation. 2014;21(1):21-30. PMID: 24135863.

 

Mathioudakis A, Chatzimavridou-Grigoriadou V, Evangelopoulou E, et al. Vasoactive intestinal Peptide inhaled agonists: potential role in respiratory therapeutics. Hippokratia. 2013 Jan;17(1):12-6. PMID: 23935337.

" Not dangerous goods.

LKT V3355 Vindoline 25 mg 61.1 Semi-synthetic vinca alkaloid found in Catharanthus; Kv2.1 K+ channel blocker and H+/K+ ATPase inhibitor. (2β,3β,4β,5α,12β,19α)-4-(Acetyloxy)-6,7-didehydro- 3-hydroxy-16-methoxy-1-methyl-aspidospermidine-3-carboxylic acid methyl ester Vindolin; NSC 91994 2182-14-1 ≥98% 456.53 C25H32N2O6 CCC12C=CCN3C1C4(CC3)C(C(C2OC(=O)C)(C(=O)OC)O)N(C5=C4C=CC(=C5)OC)C Ambient -20°C Soluble in chloroform or ethanol. "Yao XG, Chen F, Li P, et al. Natural product vindoline stimulates insulin secretion and efficiently ameliorates glucose homeostasis in diabetic murine models. J Ethnopharmacol. 2013 Oct 28;150(1):285-97. PMID: 24012527.

 

Freitas CS, Baggio CH, Mayer B, et al. Inhibition of gastric H+, K(+)-ATPase activity by compounds from medicinal plants. Nat Prod Commun. 2011 Sep;6(9):1253-4. PMID: 21941891.

 

Sertel S, Fu Y, Zu Y, et al. Molecular docking and pharmacogenomics of vinca alkaloids and their monomeric precursors, vindoline and catharanthine. Biochem Pharmacol. 2011 Mar 15;81(6):723-35. PMID: 21219884." Xn Not dangerous goods.

LKT V3355 Vindoline 100 mg 169.9 Semi-synthetic vinca alkaloid found in Catharanthus; Kv2.1 K+ channel blocker and H+/K+ ATPase inhibitor. (2β,3β,4β,5α,12β,19α)-4-(Acetyloxy)-6,7-didehydro- 3-hydroxy-16-methoxy-1-methyl-aspidospermidine-3-carboxylic acid methyl ester Vindolin; NSC 91994 2182-14-1 ≥98% 456.53 C25H32N2O6 CCC12C=CCN3C1C4(CC3)C(C(C2OC(=O)C)(C(=O)OC)O)N(C5=C4C=CC(=C5)OC)C Ambient -20°C Soluble in chloroform or ethanol. "Yao XG, Chen F, Li P, et al. Natural product vindoline stimulates insulin secretion and efficiently ameliorates glucose homeostasis in diabetic murine models. J Ethnopharmacol. 2013 Oct 28;150(1):285-97. PMID: 24012527.

 

Freitas CS, Baggio CH, Mayer B, et al. Inhibition of gastric H+, K(+)-ATPase activity by compounds from medicinal plants. Nat Prod Commun. 2011 Sep;6(9):1253-4. PMID: 21941891.

 

Sertel S, Fu Y, Zu Y, et al. Molecular docking and pharmacogenomics of vinca alkaloids and their monomeric precursors, vindoline and catharanthine. Biochem Pharmacol. 2011 Mar 15;81(6):723-35. PMID: 21219884." Xn Not dangerous goods.

LKT V3355 Vindoline 500 mg 516.4 Semi-synthetic vinca alkaloid found in Catharanthus; Kv2.1 K+ channel blocker and H+/K+ ATPase inhibitor. (2β,3β,4β,5α,12β,19α)-4-(Acetyloxy)-6,7-didehydro- 3-hydroxy-16-methoxy-1-methyl-aspidospermidine-3-carboxylic acid methyl ester Vindolin; NSC 91994 2182-14-1 ≥98% 456.53 C25H32N2O6 CCC12C=CCN3C1C4(CC3)C(C(C2OC(=O)C)(C(=O)OC)O)N(C5=C4C=CC(=C5)OC)C Ambient -20°C Soluble in chloroform or ethanol. "Yao XG, Chen F, Li P, et al. Natural product vindoline stimulates insulin secretion and efficiently ameliorates glucose homeostasis in diabetic murine models. J Ethnopharmacol. 2013 Oct 28;150(1):285-97. PMID: 24012527.

 

Freitas CS, Baggio CH, Mayer B, et al. Inhibition of gastric H+, K(+)-ATPase activity by compounds from medicinal plants. Nat Prod Commun. 2011 Sep;6(9):1253-4. PMID: 21941891.

 

Sertel S, Fu Y, Zu Y, et al. Molecular docking and pharmacogenomics of vinca alkaloids and their monomeric precursors, vindoline and catharanthine. Biochem Pharmacol. 2011 Mar 15;81(6):723-35. PMID: 21219884." Xn Not dangerous goods.

LKT V3277 Vitamin E 100 g 149.5 Synthetic vitamin E, antioxidant. D,L-α-Tocopherol; (+-)-α-Tocopherol; Ephanyl 10191-41-0 ≥98% 430.7 C29H50O2 CC1=C(C(=C2CCC(OC2=C1C)(C)CCCC(C)CCCC(C)CCCC(C)C)C)O Stable to heat and alkalis. Protect from light. Ambient 4°C Soluble in ethanol, ether, chloroform, acetone or vegetable oils. "Reid VC, Mitchinson MJ. Toxicity of oxidised low density lipoprotein towards mouse peritoneal macrophages in vitro. Atherosclerosis. 1993 Jan 4;98(1):17-24. PMID: 8457247.

 

Williams RJ, Motteram JM, Sharp CH, et al. Dietary vitamin E and the attenuation of early lesion development in modified Watanabe rabbits. Atherosclerosis. 1992 Jun;94(2-3):153-9. PMID: 1632869.

" Xi Not dangerous goods.

LKT V3276 Vitamin E, Natural 100 g 82.5 Antioxidant. D-α-tocopherol 59-02-9 ≥97% C29H50O2 CC1=C(C(=C2CCC(OC2=C1C)(C)CCCC(C)CCCC(C)CCCC(C)C)C)O Ambient 4°C "Kim do Y, Kim J, Ham HJ, et al. Effects of d-α-tocopherol supplements on lipid metabolism in a high-fat diet-fed animal model. Nutr Res Pract. 2013 Dec;7(6):481-7. PMID: 24353834.

 

Abdala-Valencia H, Berdnikovs S, Cook-Mills JM. Vitamin E isoforms differentially regulate intercellular adhesion molecule-1 activation of PKCα in human microvascular endothelial cells. PLoS One. 2012;7(7):e41054. PMID: 22815910.

 

Mirbagheri SA, Nezami BG, Assa S, et al. Rectal administration of d-alpha tocopherol for active ulcerative colitis: a preliminary report. World J Gastroenterol. 2008 Oct 21;14(39):5990-5. PMID: 18932276.

 

Wu S, Gao J, Dinh QT, et al. IL-8 production and AP-1 transactivation induced by UVA in human keratinocytes: roles of D-alpha-tocopherol. Mol Immunol. 2008 Apr;45(8):2288-96. PMID: 18206243.

 

Aydemir O, Celebi S, Yilmaz T, et al. Protective effects of vitamin E forms (alpha-tocopherol, gamma-tocopherol and d-alpha-tocopherol polyethylene glycol 1000 succinate) on retinal edema during ischemia-reperfusion injury in the guinea pig retina. Int Ophthalmol. 2004 Oct-Dec;25(5-6):283-9. PMID: 16532291.

 

Koya D, Haneda M, Kikkawa R, et al. d-alpha-tocopherol treatment prevents glomerular dysfunctions in diabetic rats through inhibition of protein kinase C-diacylglycerol pathway. Biofactors. 1998;7(1-2):69-76. PMID: 9523030.

 

Devaraj S, Li D, Jialal I. The effects of alpha tocopherol supplementation on monocyte function. Decreased lipid oxidation, interleukin 1 beta secretion, and monocyte adhesion to endothelium. J Clin Invest. 1996 Aug 1;98(3):756-63. PMID: 8698868.

" Xi Not dangerous goods.

LKT V3276 Vitamin E, Natural 250 g 171.5 Antioxidant. D-α-tocopherol 59-02-9 ≥97% C29H50O2 CC1=C(C(=C2CCC(OC2=C1C)(C)CCCC(C)CCCC(C)CCCC(C)C)C)O Ambient 4°C "Kim do Y, Kim J, Ham HJ, et al. Effects of d-α-tocopherol supplements on lipid metabolism in a high-fat diet-fed animal model. Nutr Res Pract. 2013 Dec;7(6):481-7. PMID: 24353834.

 

Abdala-Valencia H, Berdnikovs S, Cook-Mills JM. Vitamin E isoforms differentially regulate intercellular adhesion molecule-1 activation of PKCα in human microvascular endothelial cells. PLoS One. 2012;7(7):e41054. PMID: 22815910.

 

Mirbagheri SA, Nezami BG, Assa S, et al. Rectal administration of d-alpha tocopherol for active ulcerative colitis: a preliminary report. World J Gastroenterol. 2008 Oct 21;14(39):5990-5. PMID: 18932276.

 

Wu S, Gao J, Dinh QT, et al. IL-8 production and AP-1 transactivation induced by UVA in human keratinocytes: roles of D-alpha-tocopherol. Mol Immunol. 2008 Apr;45(8):2288-96. PMID: 18206243.

 

Aydemir O, Celebi S, Yilmaz T, et al. Protective effects of vitamin E forms (alpha-tocopherol, gamma-tocopherol and d-alpha-tocopherol polyethylene glycol 1000 succinate) on retinal edema during ischemia-reperfusion injury in the guinea pig retina. Int Ophthalmol. 2004 Oct-Dec;25(5-6):283-9. PMID: 16532291.

 

Koya D, Haneda M, Kikkawa R, et al. d-alpha-tocopherol treatment prevents glomerular dysfunctions in diabetic rats through inhibition of protein kinase C-diacylglycerol pathway. Biofactors. 1998;7(1-2):69-76. PMID: 9523030.

 

Devaraj S, Li D, Jialal I. The effects of alpha tocopherol supplementation on monocyte function. Decreased lipid oxidation, interleukin 1 beta secretion, and monocyte adhesion to endothelium. J Clin Invest. 1996 Aug 1;98(3):756-63. PMID: 8698868.

" Xi Not dangerous goods.

LKT V3253 Vinblastine Sulfate 5 mg 97.2 Vinca alkaloid found in Catharanthus; microtubule polymerization inhibitor. Vincaleukblastine sulfate Exal; Velban; Velbe 143-67-9 ≥96% 909.07 C46H58N4O9S H2SO4 CCC1(CC2CC(C3=C(CCN(C2)C1)C4=CC=CC=C4N3)(C5=C(C=C6C(=C5)C78CCN9C7C(C=CC9)(C(C(C8N6C)(C(=O)OC)O)OC(=O)C)CC)OC)C(=O)OC)O.OS(=O)(=O)O Ambient -20°C Slightly soluble in ethanol or water (10 parts). Practically insoluble in ether. "Pliarchopoulou K, Laschos K, Pectasides D. Current chemotherapeutic options for the treatment of advanced bladder cancer: a review. Urol Oncol. 2013 Apr;31(3):294-302. PMID: 20843708.

 

Rendine S, Pieraccini S, Sironi M. Vinblastine perturbation of tubulin protofilament structure: a computational insight. Phys Chem Chem Phys. 2010 Dec 21;12(47):15530-6. PMID: 20978652.

 

Jordan MA, Wilson L. Microtubules as a target for anticancer drugs. Nat Rev Cancer. 2004 Apr;4(4):253-65. PMID: 15057285.

" Xn Not dangerous goods.

LKT V3253 Vinblastine Sulfate 10 mg 127.1 Vinca alkaloid found in Catharanthus; microtubule polymerization inhibitor. Vincaleukblastine sulfate Exal; Velban; Velbe 143-67-9 ≥96% 909.07 C46H58N4O9S H2SO4 CCC1(CC2CC(C3=C(CCN(C2)C1)C4=CC=CC=C4N3)(C5=C(C=C6C(=C5)C78CCN9C7C(C=CC9)(C(C(C8N6C)(C(=O)OC)O)OC(=O)C)CC)OC)C(=O)OC)O.OS(=O)(=O)O Ambient -20°C Slightly soluble in ethanol or water (10 parts). Practically insoluble in ether. "Pliarchopoulou K, Laschos K, Pectasides D. Current chemotherapeutic options for the treatment of advanced bladder cancer: a review. Urol Oncol. 2013 Apr;31(3):294-302. PMID: 20843708.

 

Rendine S, Pieraccini S, Sironi M. Vinblastine perturbation of tubulin protofilament structure: a computational insight. Phys Chem Chem Phys. 2010 Dec 21;12(47):15530-6. PMID: 20978652.

 

Jordan MA, Wilson L. Microtubules as a target for anticancer drugs. Nat Rev Cancer. 2004 Apr;4(4):253-65. PMID: 15057285.

" Xn Not dangerous goods.

LKT V3252 Vinorelbine Ditartrate 1 mg 47.6 Semi-synthetic vinca alkaloid from Catharanthus; microtubule polymerization inhibitor. 3',4'-Didehydro-4'-deoxy-C'-norvincaleukoblastine ditartrate Eunades; Navelbine 125317-39-7 ≥98% 1079.1 C45H54N4O8 2C4H6O6 CCC1=CC2CC(C3=C(CN(C2)C1)C4=CC=CC=C4N3)(C5=C(C=C6C(=C5)C78CCN9C7C(C=CC9)(C(C(C8N6C)(C(=O)OC)O)OC(=O)C)CC)OC)C(=O)OC.C(C(C(=O)O)O)(C(=O)O)O.C(C(C(=O)O)O)(C(=O)O)O Ambient -20°C Soluble in water and ethanol. "Capasso A. Vinorelbine in cancer therapy. Curr Drug Targets. 2012 Jul;13(8):1065-71. PMID: 22594474.

 

Roncuzzi L, Marti G, Baiocchi D, et al. Effect of Vinorelbine on cell growth and apoptosis induction in human osteosarcoma in vitro. Oncol Rep. 2006 Jan;15(1):73-7. PMID: 16328036.

" Xi Not dangerous goods.

LKT V3252 Vinorelbine Ditartrate 5 mg 97.8 Semi-synthetic vinca alkaloid from Catharanthus; microtubule polymerization inhibitor. 3',4'-Didehydro-4'-deoxy-C'-norvincaleukoblastine ditartrate Eunades; Navelbine 125317-39-7 ≥98% 1079.1 C45H54N4O8 2C4H6O6 CCC1=CC2CC(C3=C(CN(C2)C1)C4=CC=CC=C4N3)(C5=C(C=C6C(=C5)C78CCN9C7C(C=CC9)(C(C(C8N6C)(C(=O)OC)O)OC(=O)C)CC)OC)C(=O)OC.C(C(C(=O)O)O)(C(=O)O)O.C(C(C(=O)O)O)(C(=O)O)O Ambient -20°C Soluble in water and ethanol. "Capasso A. Vinorelbine in cancer therapy. Curr Drug Targets. 2012 Jul;13(8):1065-71. PMID: 22594474.

 

Roncuzzi L, Marti G, Baiocchi D, et al. Effect of Vinorelbine on cell growth and apoptosis induction in human osteosarcoma in vitro. Oncol Rep. 2006 Jan;15(1):73-7. PMID: 16328036.

" Xi Not dangerous goods.

LKT V3252 Vinorelbine Ditartrate 25 mg 339.8 Semi-synthetic vinca alkaloid from Catharanthus; microtubule polymerization inhibitor. 3',4'-Didehydro-4'-deoxy-C'-norvincaleukoblastine ditartrate Eunades; Navelbine 125317-39-7 ≥98% 1079.1 C45H54N4O8 2C4H6O6 CCC1=CC2CC(C3=C(CN(C2)C1)C4=CC=CC=C4N3)(C5=C(C=C6C(=C5)C78CCN9C7C(C=CC9)(C(C(C8N6C)(C(=O)OC)O)OC(=O)C)CC)OC)C(=O)OC.C(C(C(=O)O)O)(C(=O)O)O.C(C(C(=O)O)O)(C(=O)O)O Ambient -20°C Soluble in water and ethanol. "Capasso A. Vinorelbine in cancer therapy. Curr Drug Targets. 2012 Jul;13(8):1065-71. PMID: 22594474.

 

Roncuzzi L, Marti G, Baiocchi D, et al. Effect of Vinorelbine on cell growth and apoptosis induction in human osteosarcoma in vitro. Oncol Rep. 2006 Jan;15(1):73-7. PMID: 16328036.

" Xi Not dangerous goods.

LKT V3251 Vinorelbine Base 1 mg 47.6 Semi-synthetic vinca alkaloid found in Catharanthus; microtubule polymerization inhibitor. 3',4'-Didehydro-4'-deoxy-C'-norvincaleukoblastine Vinorelbine; NavelbineR; KW 2307; nor-5'-anhydrovinblastine; NVB 71486-22-1 ≥90% 778.93 C45H54N4O8 CCC1=CC2CC(C3=C(CN(C2)C1)C4=CC=CC=C4N3)(C5=C(C=C6C(=C5)C78CCN9C7C(C=CC9)(C(C(C8N6C)(C(=O)OC)O)OC(=O)C)CC)OC)C(=O)OC Ambient -20°C "Capasso A. Vinorelbine in cancer therapy. Curr Drug Targets. 2012 Jul;13(8):1065-71. PMID: 22594474.

 

Roncuzzi L, Marti G, Baiocchi D, et al. Effect of Vinorelbine on cell growth and apoptosis induction in human osteosarcoma in vitro. Oncol Rep. 2006 Jan;15(1):73-7. PMID: 16328036.

" Not dangerous goods.

LKT V3251 Vinorelbine Base 5 mg 169.9 Semi-synthetic vinca alkaloid found in Catharanthus; microtubule polymerization inhibitor. 3',4'-Didehydro-4'-deoxy-C'-norvincaleukoblastine Vinorelbine; NavelbineR; KW 2307; nor-5'-anhydrovinblastine; NVB 71486-22-1 ≥90% 778.93 C45H54N4O8 CCC1=CC2CC(C3=C(CN(C2)C1)C4=CC=CC=C4N3)(C5=C(C=C6C(=C5)C78CCN9C7C(C=CC9)(C(C(C8N6C)(C(=O)OC)O)OC(=O)C)CC)OC)C(=O)OC Ambient -20°C "Capasso A. Vinorelbine in cancer therapy. Curr Drug Targets. 2012 Jul;13(8):1065-71. PMID: 22594474.

 

Roncuzzi L, Marti G, Baiocchi D, et al. Effect of Vinorelbine on cell growth and apoptosis induction in human osteosarcoma in vitro. Oncol Rep. 2006 Jan;15(1):73-7. PMID: 16328036.

" Not dangerous goods.

LKT V3251 Vinorelbine Base 25 mg 475.7 Semi-synthetic vinca alkaloid found in Catharanthus; microtubule polymerization inhibitor. 3',4'-Didehydro-4'-deoxy-C'-norvincaleukoblastine Vinorelbine; NavelbineR; KW 2307; nor-5'-anhydrovinblastine; NVB 71486-22-1 ≥90% 778.93 C45H54N4O8 CCC1=CC2CC(C3=C(CN(C2)C1)C4=CC=CC=C4N3)(C5=C(C=C6C(=C5)C78CCN9C7C(C=CC9)(C(C(C8N6C)(C(=O)OC)O)OC(=O)C)CC)OC)C(=O)OC Ambient -20°C "Capasso A. Vinorelbine in cancer therapy. Curr Drug Targets. 2012 Jul;13(8):1065-71. PMID: 22594474.

 

Roncuzzi L, Marti G, Baiocchi D, et al. Effect of Vinorelbine on cell growth and apoptosis induction in human osteosarcoma in vitro. Oncol Rep. 2006 Jan;15(1):73-7. PMID: 16328036.

" Not dangerous goods.

LKT V3212 Vidarabine 100 mg 47.6 Nucleoside (adenosine) analog; viral DNA polymerase and ribonucleotide reductase inhibitor. 9-β-D-Aribinofuranosyl-9H-purine-6-amine monohydrate Arabinosyladenine; Adenine Arabinoside; Spongoadenosine; Ara-A; Arasena-A; Vira-A 5536-17-4 ≥98% 267.24 C10H13N5O4 C1=NC2=C(C(=N1)N)N=CN2C3C(C(C(O3)CO)O)O Ambient -20°C "Whitley RJ. The use of antiviral drugs during the neonatal period. Clin Perinatol. 2012 Mar;39(1):69-81. PMID: 22341538.

 

Wilhelmus KR. Antiviral treatment and other therapeutic interventions for herpes simplex virus epithelial keratitis. Cochrane Database Syst Rev. 2010 Dec 8;(12):CD002898. PMID: 21154352.

 

Sagar S, Kaur M, Minneman KP. Antiviral lead compounds from marine sponges. Mar Drugs. 2010 Oct 11;8(10):2619-38. PMID: 21116410.

 

Kurosaki K, Miwa N, Yoshida Y, et al. Therapeutic basis of vidarabine on adenovirus-induced haemorrhagic cystitis. Antivir Chem Chemother. 2004 Sep;15(5):281-5. PMID: 15535050.

 

Niwa K, Tagami K, Lian Z, et al. Topical vidarabine or 5-fluorouracil treatment against persistent HPV in genital (pre)cancerous lesions. Oncol Rep. 2003 Sep-Oct;10(5):1437-41. PMID: 12883720.

 

Kimura H, Morita M, Tsuge I, et al. Vidarabine therapy for severe chronic active Epstein-Barr virus infection. J Pediatr Hematol Oncol. 2001 Jun-Jul;23(5):294-9. PMID: 11464986.

 

Nimit Y, Law J, Daly JW. Binding of 2',5'-dideoxyadenosine to brain membranes. Comparison to P-site inhibition of adenylate cyclase. Biochem Pharmacol. 1982 Oct 15;31(20):3279-87. PMID: 6983353.

" Repr. Not dangerous goods.

LKT V3212 Vidarabine 500 mg 122.3 Nucleoside (adenosine) analog; viral DNA polymerase and ribonucleotide reductase inhibitor. 9-β-D-Aribinofuranosyl-9H-purine-6-amine monohydrate Arabinosyladenine; Adenine Arabinoside; Spongoadenosine; Ara-A; Arasena-A; Vira-A 5536-17-4 ≥98% 267.24 C10H13N5O4 C1=NC2=C(C(=N1)N)N=CN2C3C(C(C(O3)CO)O)O Ambient -20°C "Whitley RJ. The use of antiviral drugs during the neonatal period. Clin Perinatol. 2012 Mar;39(1):69-81. PMID: 22341538.

 

Wilhelmus KR. Antiviral treatment and other therapeutic interventions for herpes simplex virus epithelial keratitis. Cochrane Database Syst Rev. 2010 Dec 8;(12):CD002898. PMID: 21154352.

 

Sagar S, Kaur M, Minneman KP. Antiviral lead compounds from marine sponges. Mar Drugs. 2010 Oct 11;8(10):2619-38. PMID: 21116410.

 

Kurosaki K, Miwa N, Yoshida Y, et al. Therapeutic basis of vidarabine on adenovirus-induced haemorrhagic cystitis. Antivir Chem Chemother. 2004 Sep;15(5):281-5. PMID: 15535050.

 

Niwa K, Tagami K, Lian Z, et al. Topical vidarabine or 5-fluorouracil treatment against persistent HPV in genital (pre)cancerous lesions. Oncol Rep. 2003 Sep-Oct;10(5):1437-41. PMID: 12883720.

 

Kimura H, Morita M, Tsuge I, et al. Vidarabine therapy for severe chronic active Epstein-Barr virus infection. J Pediatr Hematol Oncol. 2001 Jun-Jul;23(5):294-9. PMID: 11464986.

 

Nimit Y, Law J, Daly JW. Binding of 2',5'-dideoxyadenosine to brain membranes. Comparison to P-site inhibition of adenylate cyclase. Biochem Pharmacol. 1982 Oct 15;31(20):3279-87. PMID: 6983353.

" Repr. Not dangerous goods.

LKT V3212 Vidarabine 1 g 169.9 Nucleoside (adenosine) analog; viral DNA polymerase and ribonucleotide reductase inhibitor. 9-β-D-Aribinofuranosyl-9H-purine-6-amine monohydrate Arabinosyladenine; Adenine Arabinoside; Spongoadenosine; Ara-A; Arasena-A; Vira-A 5536-17-4 ≥98% 267.24 C10H13N5O4 C1=NC2=C(C(=N1)N)N=CN2C3C(C(C(O3)CO)O)O Ambient -20°C "Whitley RJ. The use of antiviral drugs during the neonatal period. Clin Perinatol. 2012 Mar;39(1):69-81. PMID: 22341538.

 

Wilhelmus KR. Antiviral treatment and other therapeutic interventions for herpes simplex virus epithelial keratitis. Cochrane Database Syst Rev. 2010 Dec 8;(12):CD002898. PMID: 21154352.

 

Sagar S, Kaur M, Minneman KP. Antiviral lead compounds from marine sponges. Mar Drugs. 2010 Oct 11;8(10):2619-38. PMID: 21116410.

 

Kurosaki K, Miwa N, Yoshida Y, et al. Therapeutic basis of vidarabine on adenovirus-induced haemorrhagic cystitis. Antivir Chem Chemother. 2004 Sep;15(5):281-5. PMID: 15535050.

 

Niwa K, Tagami K, Lian Z, et al. Topical vidarabine or 5-fluorouracil treatment against persistent HPV in genital (pre)cancerous lesions. Oncol Rep. 2003 Sep-Oct;10(5):1437-41. PMID: 12883720.

 

Kimura H, Morita M, Tsuge I, et al. Vidarabine therapy for severe chronic active Epstein-Barr virus infection. J Pediatr Hematol Oncol. 2001 Jun-Jul;23(5):294-9. PMID: 11464986.

 

Nimit Y, Law J, Daly JW. Binding of 2',5'-dideoxyadenosine to brain membranes. Comparison to P-site inhibition of adenylate cyclase. Biochem Pharmacol. 1982 Oct 15;31(20):3279-87. PMID: 6983353.

" Repr. Not dangerous goods.

LKT C0367 S-(−)-Carbidopa Monohydrate 25 mg 40.7 Hydrazine; L-amino acid decarboxylase inhibitor. 38821-49-7 ≥98% 244.24 C10H14N2O4 H2O CC(CC1=CC(=C(C=C1)O)O)(C(=O)O)NN.O Ambient Ambient "Katow H, Suyemitsu T, Ooka S, et al. Development of a dopaminergic system in sea urchin embryos and larvae. J Exp Biol. 2010 Aug 15;213(Pt 16):2808-19. PMID: 20675551.

 

Thomas SA, Marck BT, Palmiter RD, et al. Restoration of norepinephrine and reversal of phenotypes in mice lacking dopamine beta-hydroxylase. J Neurochem. 1998 Jun;70(6):2468-76. PMID: 9603211.

" Not dangerous goods.

LKT C0367 S-(−)-Carbidopa Monohydrate 100 mg 88.3 Hydrazine; L-amino acid decarboxylase inhibitor. 38821-49-7 ≥98% 244.24 C10H14N2O4 H2O CC(CC1=CC(=C(C=C1)O)O)(C(=O)O)NN.O Ambient Ambient "Katow H, Suyemitsu T, Ooka S, et al. Development of a dopaminergic system in sea urchin embryos and larvae. J Exp Biol. 2010 Aug 15;213(Pt 16):2808-19. PMID: 20675551.

 

Thomas SA, Marck BT, Palmiter RD, et al. Restoration of norepinephrine and reversal of phenotypes in mice lacking dopamine beta-hydroxylase. J Neurochem. 1998 Jun;70(6):2468-76. PMID: 9603211.

" Not dangerous goods.

LKT V1872 Vesicular Stomatitis Virus Peptide 1 mg 60 Peptide fragment of VSV; LDLR agonist. ≥95% 955.09 C44H66N12O12 Ambient -20°C "Ammayappan A, Peng KW, Russell SJ. Characteristics of oncolytic vesicular stomatitis virus displaying tumor-targeting ligands. J Virol. 2013 Dec;87(24):13543-55. PMID: 24089573.

 

Randle RW, Northrup SA, Sirintrapun SJ, et al. Oncolytic vesicular stomatitis virus as a treatment for neuroendocrine tumors. Surgery. 2013 Dec;154(6):1323-29; discussion 1329-30. PMID: 23973113.

 

Naik S, Nace R, Barber GN, et al. Potent systemic therapy of multiple myeloma utilizing oncolytic vesicular stomatitis virus coding for interferon-β. Cancer Gene Ther. 2012 Jul;19(7):443-50. PMID: 22522623.

"

LKT V1872 Vesicular Stomatitis Virus Peptide 2 mg 111 Peptide fragment of VSV; LDLR agonist. ≥95% 955.09 C44H66N12O12 Ambient -20°C "Ammayappan A, Peng KW, Russell SJ. Characteristics of oncolytic vesicular stomatitis virus displaying tumor-targeting ligands. J Virol. 2013 Dec;87(24):13543-55. PMID: 24089573.

 

Randle RW, Northrup SA, Sirintrapun SJ, et al. Oncolytic vesicular stomatitis virus as a treatment for neuroendocrine tumors. Surgery. 2013 Dec;154(6):1323-29; discussion 1329-30. PMID: 23973113.

 

Naik S, Nace R, Barber GN, et al. Potent systemic therapy of multiple myeloma utilizing oncolytic vesicular stomatitis virus coding for interferon-β. Cancer Gene Ther. 2012 Jul;19(7):443-50. PMID: 22522623.

"

LKT V1872 Vesicular Stomatitis Virus Peptide 5 mg 198.1 Peptide fragment of VSV; LDLR agonist. ≥95% 955.09 C44H66N12O12 Ambient -20°C "Ammayappan A, Peng KW, Russell SJ. Characteristics of oncolytic vesicular stomatitis virus displaying tumor-targeting ligands. J Virol. 2013 Dec;87(24):13543-55. PMID: 24089573.

 

Randle RW, Northrup SA, Sirintrapun SJ, et al. Oncolytic vesicular stomatitis virus as a treatment for neuroendocrine tumors. Surgery. 2013 Dec;154(6):1323-29; discussion 1329-30. PMID: 23973113.

 

Naik S, Nace R, Barber GN, et al. Potent systemic therapy of multiple myeloma utilizing oncolytic vesicular stomatitis virus coding for interferon-β. Cancer Gene Ther. 2012 Jul;19(7):443-50. PMID: 22522623.

"

LKT V1870 Verruculogen 1 mg 134.9 Mycotoxin produced by Aspergillus; BK K+ channel blocker, GABA-A antagonist. 12771-72-1 ≥95% 511.57 C27H33N3O7 CC(=CC1N2C3=C(C=CC(=C3)OC)C4=C2C(CC(OO1)(C)C)N5C(=O)C6CCCN6C(=O)C5(C4O)O)C Ambient 4°C DMSO, Methanol, Ethanol "Smith RC, McClure MC, Smith MA, et al. The role of voltage-gated potassium channels in the regulation of mouse uterine contractility. Reprod Biol Endocrinol. 2007 Nov 2;5:41. PMID: 17980032.

 

Kosalec I, Klarić MS, Pepeljnjak S. Verruculogen production in airborne and clinical isolates of Aspergillus fumigatus Fres. Acta Pharm. 2005 Dec;55(4):357-64. PMID: 16375825.

 

Knaus HG, McManus OB, Lee SH, et al. Tremorgenic indole alkaloids potently inhibit smooth muscle high-conductance calcium-activated potassium channels. Biochemistry. 1994 May 17;33(19):5819-28. PMID: 7514038.

 

Gant DB, Cole RJ, Valdes JJ, et al. Action of tremorgenic mycotoxins on GABAA receptor. Life Sci. 1987 Nov 9;41(19):2207-14. PMID: 2444852.

" T "UN number: 3462     Class: 6.1     Packing Group: III

Proper shipping name: Toxins, extracted from living sources, solid, n.o.s. (Verruculogen)"

LKT V1870 Verruculogen 5 mg 559 Mycotoxin produced by Aspergillus; BK K+ channel blocker, GABA-A antagonist. 12771-72-1 ≥95% 511.57 C27H33N3O7 CC(=CC1N2C3=C(C=CC(=C3)OC)C4=C2C(CC(OO1)(C)C)N5C(=O)C6CCCN6C(=O)C5(C4O)O)C Ambient 4°C DMSO, Methanol, Ethanol "Smith RC, McClure MC, Smith MA, et al. The role of voltage-gated potassium channels in the regulation of mouse uterine contractility. Reprod Biol Endocrinol. 2007 Nov 2;5:41. PMID: 17980032.

 

Kosalec I, Klarić MS, Pepeljnjak S. Verruculogen production in airborne and clinical isolates of Aspergillus fumigatus Fres. Acta Pharm. 2005 Dec;55(4):357-64. PMID: 16375825.

 

Knaus HG, McManus OB, Lee SH, et al. Tremorgenic indole alkaloids potently inhibit smooth muscle high-conductance calcium-activated potassium channels. Biochemistry. 1994 May 17;33(19):5819-28. PMID: 7514038.

 

Gant DB, Cole RJ, Valdes JJ, et al. Action of tremorgenic mycotoxins on GABAA receptor. Life Sci. 1987 Nov 9;41(19):2207-14. PMID: 2444852.

" T "UN number: 3462     Class: 6.1     Packing Group: III

Proper shipping name: Toxins, extracted from living sources, solid, n.o.s. (Verruculogen)"

LKT V1854 Venlaaxine Hydrochloride 500 mg 74 SERT, NET, MAO inhibitor. 1-(2-(dimethylamino)-1-(4-methoxyphenyl)ethyl)- cyclohexanol hydrochloride Effexor; HSDB 6699; Wy 45030 99300-78-4 ≥98% 313.87 C17H27NO2 HCl CN(C)CC(C1=CC=C(C=C1)OC)C2(CCCCC2)O.Cl Light sensitive. Ambient Ambient Soluble in water. "Vidal R, Diaz A, Pazos A, et al. Region-specific regulation of 5-HT1B receptors in the rat brain by chronic venlaaxine treatment. Psychopharmacology (Berl). 2013 Sep;229(1):177-85. PMID: 23609771.

 

Cegielska-Perun K, Bujalska-Zadrożny M, Tatarkiewicz J, et al. Venlaaxine and neuropathic pain. Pharmacology. 2013;91(1-2):69-76. PMID: 23183148.

 

Fisar Z, Hroudová J, Raboch J. Inhibition of monoamine oxidase activity by antidepressants and mood stabilizers. Neuro Endocrinol Lett. 2010;31(5):645-56. PMID: 21200377.

 

Kumar P, Kalonia H, Kumar A. Nitric oxide mechanism in the protective effect of antidepressants against 3-nitropropionic acid-induced cognitive deficit, glutathione and mitochondrial alterations in animal model of Huntington's disease. Behav Pharmacol. 2010 May;21(3):217-30. PMID: 20480544.

" Xi Not dangerous goods.

LKT V1854 Venlafaine Hydrochloride 1 g 120.1 SERT, NET, MAO inhibitor. 1-(2-(dimethylamino)-1-(4-methoxyphenyl)ethyl)- cyclohexanol hydrochloride Effexor; HSDB 6699; Wy 45030 99300-78-4 ≥98% 313.87 C17H27NO2 HCl CN(C)CC(C1=CC=C(C=C1)OC)C2(CCCCC2)O.Cl Light sensitive. Ambient Ambient Soluble in water. "Vidal R, Diaz A, Pazos A, et al. Region-specific regulation of 5-HT1B receptors in the rat brain by chronic venlafaine treatment. Psychopharmacology (Berl). 2013 Sep;229(1):177-85. PMID: 23609771.

 

Cegielska-Perun K, Bujalska-Zadrożny M, Tatarkiewicz J, et al. Venlafxine and neuropathic pain. Pharmacology. 2013;91(1-2):69-76. PMID: 23183148.

 

Fisar Z, Hroudová J, Raboch J. Inhibition of monoamine oxidase activity by antidepressants and mood stabilizers. Neuro Endocrinol Lett. 2010;31(5):645-56. PMID: 21200377.

 

Kumar P, Kalonia H, Kumar A. Nitric oxide mechanism in the protective effect of antidepressants against 3-nitropropionic acid-induced cognitive deficit, glutathione and mitochondrial alterations in animal model of Huntington's disease. Behav Pharmacol. 2010 May;21(3):217-30. PMID: 20480544.

" Xi Not dangerous goods.

LKT V1854 Venlaaxine Hydrochloride 5 g 496.9 SERT, NET, MAO inhibitor. 1-(2-(dimethylamino)-1-(4-methoxyphenyl)ethyl)- cyclohexanol hydrochloride Effexor; HSDB 6699; Wy 45030 99300-78-4 ≥98% 313.87 C17H27NO2 HCl CN(C)CC(C1=CC=C(C=C1)OC)C2(CCCCC2)O.Cl Light sensitive. Ambient Ambient Soluble in water. "Vidal R, Diaz A, Pazos A, et al. Region-specific regulation of 5-HT1B receptors in the rat brain by chronic venlafxine treatment. Psychopharmacology (Berl). 2013 Sep;229(1):177-85. PMID: 23609771.

 

Cegielska-Perun K, Bujalska-Zadrożny M, Tatarkiewicz J, et al. Venlaaxine and neuropathic pain. Pharmacology. 2013;91(1-2):69-76. PMID: 23183148.

 

Fisar Z, Hroudová J, Raboch J. Inhibition of monoamine oxidase activity by antidepressants and mood stabilizers. Neuro Endocrinol Lett. 2010;31(5):645-56. PMID: 21200377.

 

Kumar P, Kalonia H, Kumar A. Nitric oxide mechanism in the protective effect of antidepressants against 3-nitropropionic acid-induced cognitive deficit, glutathione and mitochondrial alterations in animal model of Huntington's disease. Behav Pharmacol. 2010 May;21(3):217-30. PMID: 20480544.

" Xi Not dangerous goods.

LKT C0372 Casein Kinase 2 Assay Kit 1 mg 209.8 Casein kinase 2 substrate. ≥95% 1264.2 C45H73N19O24 Ambient -20°C "Raüber C, Berger S. Saturation transfer difference NMR studies of the interaction of the proteinkinase CK2 with peptides. Protein Pept Lett. 2012 Sep;19(9):934-9. PMID: 22486610.

 

Gratz A, Kuckländer U, Bollig R, et al. Identification of novel CK2 inhibitors with a benzofuran scaffold by novel non-radiometric in vitro assays. Mol Cell Biochem. 2011 Oct;356(1-2):83-90. PMID: 21750981.

" Not dangerous goods.

LKT C0372 Casein Kinase 2 Assay Kit 2 mg 354.3 Casein kinase 2 substrate. ≥95% 1264.2 C45H73N19O24 Ambient -20°C "Raüber C, Berger S. Saturation transfer difference NMR studies of the interaction of the proteinkinase CK2 with peptides. Protein Pept Lett. 2012 Sep;19(9):934-9. PMID: 22486610.

 

Gratz A, Kuckländer U, Bollig R, et al. Identification of novel CK2 inhibitors with a benzofuran scaffold by novel non-radiometric in vitro assays. Mol Cell Biochem. 2011 Oct;356(1-2):83-90. PMID: 21750981.

" Not dangerous goods.

LKT C0372 Casein Kinase 2 Assay Kit 5 mg 623.9 Casein kinase 2 substrate. ≥95% 1264.2 C45H73N19O24 Ambient -20°C "Raüber C, Berger S. Saturation transfer difference NMR studies of the interaction of the proteinkinase CK2 with peptides. Protein Pept Lett. 2012 Sep;19(9):934-9. PMID: 22486610.

 

Gratz A, Kuckländer U, Bollig R, et al. Identification of novel CK2 inhibitors with a benzofuran scaffold by novel non-radiometric in vitro assays. Mol Cell Biochem. 2011 Oct;356(1-2):83-90. PMID: 21750981.

" Not dangerous goods.

LKT C0374 β-Casomorphin, human 5 mg 83.9 Peptide, casein fragment. beta-casomorphin ≥95% 864.02 C44H61N7O11 Ambient -20°C "Zhang W, Miao J, Wang S, et al. The protective effects of beta-casomorphin-7 against glucose -induced renal oxidative stress in vivo and vitro. PLoS One. 2013 May 3;8(5):e63472. PMID: 23658831.

 

Zhang W, Miao J, Ma C, et al. β-Casomorphin-7 attenuates the development of nephropathy in type I diabetes via inhibition of epithelial-mesenchymal transition of renal tubular epithelial cells. Peptides. 2012 Aug;36(2):186-91. PMID: 22687367.

" Not dangerous goods.

LKT C0374 β-Casomorphin, human 10 mg 144 Peptide, casein fragment. beta-casomorphin ≥95% 864.02 C44H61N7O11 Ambient -20°C "Zhang W, Miao J, Wang S, et al. The protective effects of beta-casomorphin-7 against glucose -induced renal oxidative stress in vivo and vitro. PLoS One. 2013 May 3;8(5):e63472. PMID: 23658831.

 

Zhang W, Miao J, Ma C, et al. β-Casomorphin-7 attenuates the development of nephropathy in type I diabetes via inhibition of epithelial-mesenchymal transition of renal tubular epithelial cells. Peptides. 2012 Aug;36(2):186-91. PMID: 22687367.

" Not dangerous goods.

LKT C0374 β-Casomorphin, human 25 mg 252.1 Peptide, casein fragment. beta-casomorphin ≥95% 864.02 C44H61N7O11 Ambient -20°C "Zhang W, Miao J, Wang S, et al. The protective effects of beta-casomorphin-7 against glucose -induced renal oxidative stress in vivo and vitro. PLoS One. 2013 May 3;8(5):e63472. PMID: 23658831.

 

Zhang W, Miao J, Ma C, et al. β-Casomorphin-7 attenuates the development of nephropathy in type I diabetes via inhibition of epithelial-mesenchymal transition of renal tubular epithelial cells. Peptides. 2012 Aug;36(2):186-91. PMID: 22687367.

" Not dangerous goods.

LKT C0375 Ac-DEVD-pNA 1 mg 63 Caspase 3 substrate. Caspase 3 substrate, colorimetric ≥95% 638.6 C26H34N6O13 Ambient -20°C "Mahdavi M, Davoodi J, Zali MR, et al. Concomitant activation of caspase-9 and down-regulation of IAP proteins as a mechanism of apoptotic death in HepG2, T47D and HCT-116 cells upon exposure to a derivative from 4-aryl-4H-chromenes family. Biomed Pharmacother. 2011 Jun;65(3):175-82. PMID: 21565459.

 

Kluza J, Lansiaux A, Wattez N, et al. Apoptotic response of HL-60 human leukemia cells to the antitumor drug TAS-103. Cancer Res. 2000 Aug 1;60(15):4077-84. PMID: 10945613

" Not dangerous goods.

LKT C0375 Ac-DEVD-pNA 2 mg 107.8 Caspase 3 substrate. Caspase 3 substrate, colorimetric ≥95% 638.6 C26H34N6O13 Ambient -20°C "Mahdavi M, Davoodi J, Zali MR, et al. Concomitant activation of caspase-9 and down-regulation of IAP proteins as a mechanism of apoptotic death in HepG2, T47D and HCT-116 cells upon exposure to a derivative from 4-aryl-4H-chromenes family. Biomed Pharmacother. 2011 Jun;65(3):175-82. PMID: 21565459.

 

Kluza J, Lansiaux A, Wattez N, et al. Apoptotic response of HL-60 human leukemia cells to the antitumor drug TAS-103. Cancer Res. 2000 Aug 1;60(15):4077-84. PMID: 10945613

" Not dangerous goods.

LKT C0375 Ac-DEVD-pNA 5 mg 186 Caspase 3 substrate. Caspase 3 substrate, colorimetric ≥95% 638.6 C26H34N6O13 Ambient -20°C "Mahdavi M, Davoodi J, Zali MR, et al. Concomitant activation of caspase-9 and down-regulation of IAP proteins as a mechanism of apoptotic death in HepG2, T47D and HCT-116 cells upon exposure to a derivative from 4-aryl-4H-chromenes family. Biomed Pharmacother. 2011 Jun;65(3):175-82. PMID: 21565459.

 

Kluza J, Lansiaux A, Wattez N, et al. Apoptotic response of HL-60 human leukemia cells to the antitumor drug TAS-103. Cancer Res. 2000 Aug 1;60(15):4077-84. PMID: 10945613

" Not dangerous goods.

LKT C0376 Catharanthine base 25 mg 147.5 Alkaloid found in Catharanthus, precursor in synthesis of vinca alkaloids; voltage-gated Ca2+ channel blocker. 2468-21-5 ≥98% 336.43 C21H24N2O2 CCC1=CC2CC3(C1N(C2)CCC4=C3NC5=CC=CC=C45)C(=O)OC Ambient 4°C "Munigunti R, Becker K, Brun R, et al. Determination of antiplasmodial activity and binding affinity of selected natural products towards PfTrxR and PfGR. Nat Prod Commun. 2013 Aug;8(8):1135-6. PMID: 24079187.

 

Jadhav A, Liang W, Papageorgiou PC, et al. Catharanthine dilates small mesenteric arteries and decreases heart rate and cardiac contractility by inhibition of voltage-operated calcium channels on vascular smooth muscle cells and cardiomyocytes. J Pharmacol Exp Ther. 2013 Jun;345(3):383-92. PMID: 23532933.

 

Sertel S, Fu Y, Zu Y, et al. Molecular docking and pharmacogenomics of vinca alkaloids and their monomeric precursors, vindoline and catharanthine. Biochem Pharmacol. 2011 Mar 15;81(6):723-35. PMID: 21219884.

" U/A Not dangerous goods.

LKT C0376 Catharanthine base 100 mg 364.6 Alkaloid found in Catharanthus, precursor in synthesis of vinca alkaloids; voltage-gated Ca2+ channel blocker. 2468-21-5 ≥98% 336.43 C21H24N2O2 CCC1=CC2CC3(C1N(C2)CCC4=C3NC5=CC=CC=C45)C(=O)OC Ambient 4°C "Munigunti R, Becker K, Brun R, et al. Determination of antiplasmodial activity and binding affinity of selected natural products towards PfTrxR and PfGR. Nat Prod Commun. 2013 Aug;8(8):1135-6. PMID: 24079187.

 

Jadhav A, Liang W, Papageorgiou PC, et al. Catharanthine dilates small mesenteric arteries and decreases heart rate and cardiac contractility by inhibition of voltage-operated calcium channels on vascular smooth muscle cells and cardiomyocytes. J Pharmacol Exp Ther. 2013 Jun;345(3):383-92. PMID: 23532933.

 

Sertel S, Fu Y, Zu Y, et al. Molecular docking and pharmacogenomics of vinca alkaloids and their monomeric precursors, vindoline and catharanthine. Biochem Pharmacol. 2011 Mar 15;81(6):723-35. PMID: 21219884.

" U/A Not dangerous goods.

LKT C0376 Catharanthine base 500 mg 1237.6 Alkaloid found in Catharanthus, precursor in synthesis of vinca alkaloids; voltage-gated Ca2+ channel blocker. 2468-21-5 ≥98% 336.43 C21H24N2O2 CCC1=CC2CC3(C1N(C2)CCC4=C3NC5=CC=CC=C45)C(=O)OC Ambient 4°C "Munigunti R, Becker K, Brun R, et al. Determination of antiplasmodial activity and binding affinity of selected natural products towards PfTrxR and PfGR. Nat Prod Commun. 2013 Aug;8(8):1135-6. PMID: 24079187.

 

Jadhav A, Liang W, Papageorgiou PC, et al. Catharanthine dilates small mesenteric arteries and decreases heart rate and cardiac contractility by inhibition of voltage-operated calcium channels on vascular smooth muscle cells and cardiomyocytes. J Pharmacol Exp Ther. 2013 Jun;345(3):383-92. PMID: 23532933.

 

Sertel S, Fu Y, Zu Y, et al. Molecular docking and pharmacogenomics of vinca alkaloids and their monomeric precursors, vindoline and catharanthine. Biochem Pharmacol. 2011 Mar 15;81(6):723-35. PMID: 21219884.

" U/A Not dangerous goods.

LKT V1810 Vecuronium Bromide 10 mg 61.1 Non-depolarizing NMJ blocker; nAChR antagonist. 1-[(2α,3β5α,16β,17β)-3,17-Bis(acetyloxy)-2-(1- piperidinyl)androstan-16-yl]-1-methylpiperidinium bromide Musculax; Norcuron; NC-45; Org-NC-45 50700-72-6 ≥98% 637.74 C34H57BrN2O4 CC(=O)OC1CC2CCC3C(C2(CC1N4CCCCC4)C)CCC5(C3CC(C5OC(=O)C)[N+]6(CCCCC6)C)C.[Br-] Ambient -20°C Soluble in water. "de Boer HD. Neuromuscular transmission: new concepts and agents. J Crit Care. 2009 Mar;24(1):36-42. PMID: 19272537.

 

Jonsson M, Gurley D, Dabrowski M, et al. Distinct pharmacologic properties of neuromuscular blocking agents on human neuronal nicotinic acetylcholine receptors: a possible explanation for the train-of-four fade. Anesthesiology. 2006 Sep;105(3):521-33. PMID: 16931985.

" Xi Not dangerous goods.

LKT V1810 Vecuronium Bromide 50 mg 163.2 Non-depolarizing NMJ blocker; nAChR antagonist. 1-[(2α,3β5α,16β,17β)-3,17-Bis(acetyloxy)-2-(1- piperidinyl)androstan-16-yl]-1-methylpiperidinium bromide Musculax; Norcuron; NC-45; Org-NC-45 50700-72-6 ≥98% 637.74 C34H57BrN2O4 CC(=O)OC1CC2CCC3C(C2(CC1N4CCCCC4)C)CCC5(C3CC(C5OC(=O)C)[N+]6(CCCCC6)C)C.[Br-] Ambient -20°C Soluble in water. "de Boer HD. Neuromuscular transmission: new concepts and agents. J Crit Care. 2009 Mar;24(1):36-42. PMID: 19272537.

 

Jonsson M, Gurley D, Dabrowski M, et al. Distinct pharmacologic properties of neuromuscular blocking agents on human neuronal nicotinic acetylcholine receptors: a possible explanation for the train-of-four fade. Anesthesiology. 2006 Sep;105(3):521-33. PMID: 16931985.

" Xi Not dangerous goods.

LKT V1810 Vecuronium Bromide 100 mg 285.4 Non-depolarizing NMJ blocker; nAChR antagonist. 1-[(2α,3β5α,16β,17β)-3,17-Bis(acetyloxy)-2-(1- piperidinyl)androstan-16-yl]-1-methylpiperidinium bromide Musculax; Norcuron; NC-45; Org-NC-45 50700-72-6 ≥98% 637.74 C34H57BrN2O4 CC(=O)OC1CC2CCC3C(C2(CC1N4CCCCC4)C)CCC5(C3CC(C5OC(=O)C)[N+]6(CCCCC6)C)C.[Br-] Ambient -20°C Soluble in water. "de Boer HD. Neuromuscular transmission: new concepts and agents. J Crit Care. 2009 Mar;24(1):36-42. PMID: 19272537.

 

Jonsson M, Gurley D, Dabrowski M, et al. Distinct pharmacologic properties of neuromuscular blocking agents on human neuronal nicotinic acetylcholine receptors: a possible explanation for the train-of-four fade. Anesthesiology. 2006 Sep;105(3):521-33. PMID: 16931985.

" Xi Not dangerous goods.

LKT C0377 Catharanthine Sulfate 25 mg 122 Alkaloid found in Catharanthus, precursor in synthesis of vinca alkaloids; voltage-gated Ca2+ channel blocker. ≥98% 434.51 C21H24N2O2 H2SO4 CCC1=CC2CC3(C1N(C2)CCC4=C3NC5=CC=CC=C45)C(=O)OC.OS(=O)(=O)O Ambient 4°C "Munigunti R, Becker K, Brun R, et al. Determination of antiplasmodial activity and binding affinity of selected natural products towards PfTrxR and PfGR. Nat Prod Commun. 2013 Aug;8(8):1135-6. PMID: 24079187.

 

Jadhav A, Liang W, Papageorgiou PC, et al. Catharanthine dilates small mesenteric arteries and decreases heart rate and cardiac contractility by inhibition of voltage-operated calcium channels on vascular smooth muscle cells and cardiomyocytes. J Pharmacol Exp Ther. 2013 Jun;345(3):383-92. PMID: 23532933.

 

Sertel S, Fu Y, Zu Y, et al. Molecular docking and pharmacogenomics of vinca alkaloids and their monomeric precursors, vindoline and catharanthine. Biochem Pharmacol. 2011 Mar 15;81(6):723-35. PMID: 21219884.

" Not dangerous.

LKT C0377 Catharanthine Sulfate 100 mg 351 Alkaloid found in Catharanthus, precursor in synthesis of vinca alkaloids; voltage-gated Ca2+ channel blocker. ≥98% 434.51 C21H24N2O2 H2SO4 CCC1=CC2CC3(C1N(C2)CCC4=C3NC5=CC=CC=C45)C(=O)OC.OS(=O)(=O)O Ambient 4°C "Munigunti R, Becker K, Brun R, et al. Determination of antiplasmodial activity and binding affinity of selected natural products towards PfTrxR and PfGR. Nat Prod Commun. 2013 Aug;8(8):1135-6. PMID: 24079187.

 

Jadhav A, Liang W, Papageorgiou PC, et al. Catharanthine dilates small mesenteric arteries and decreases heart rate and cardiac contractility by inhibition of voltage-operated calcium channels on vascular smooth muscle cells and cardiomyocytes. J Pharmacol Exp Ther. 2013 Jun;345(3):383-92. PMID: 23532933.

 

Sertel S, Fu Y, Zu Y, et al. Molecular docking and pharmacogenomics of vinca alkaloids and their monomeric precursors, vindoline and catharanthine. Biochem Pharmacol. 2011 Mar 15;81(6):723-35. PMID: 21219884.

" Not dangerous.

LKT C0377 Catharanthine Sulfate 500 mg 1189.1 Alkaloid found in Catharanthus, precursor in synthesis of vinca alkaloids; voltage-gated Ca2+ channel blocker. ≥98% 434.51 C21H24N2O2 H2SO4 CCC1=CC2CC3(C1N(C2)CCC4=C3NC5=CC=CC=C45)C(=O)OC.OS(=O)(=O)O Ambient 4°C "Munigunti R, Becker K, Brun R, et al. Determination of antiplasmodial activity and binding affinity of selected natural products towards PfTrxR and PfGR. Nat Prod Commun. 2013 Aug;8(8):1135-6. PMID: 24079187.

 

Jadhav A, Liang W, Papageorgiou PC, et al. Catharanthine dilates small mesenteric arteries and decreases heart rate and cardiac contractility by inhibition of voltage-operated calcium channels on vascular smooth muscle cells and cardiomyocytes. J Pharmacol Exp Ther. 2013 Jun;345(3):383-92. PMID: 23532933.

 

Sertel S, Fu Y, Zu Y, et al. Molecular docking and pharmacogenomics of vinca alkaloids and their monomeric precursors, vindoline and catharanthine. Biochem Pharmacol. 2011 Mar 15;81(6):723-35. PMID: 21219884.

" Not dangerous.

LKT C0378 Catharanthine Tartrate 25 mg 122 Alkaloid found in Catharanthus, precursor in synthesis of vinca alkaloids; voltage-gated Ca2+ channel blocker. 3,4-Didehydroibogamine-18-carboxylic acid methyl ester Catharanthine ≥97% 486.52 C21H24N2O2 C4H6O6 CCC1=CC2CC3(C1N(C2)CCC4=C3NC5=CC=CC=C45)C(=O)OC.C(C(C(=O)O)O)(C(=O)O)O Very hygroscopic. Ambient 4°C Soluble in ethanol. "Munigunti R, Becker K, Brun R, et al. Determination of antiplasmodial activity and binding affinity of selected natural products towards PfTrxR and PfGR. Nat Prod Commun. 2013 Aug;8(8):1135-6. PMID: 24079187.

 

Jadhav A, Liang W, Papageorgiou PC, et al. Catharanthine dilates small mesenteric arteries and decreases heart rate and cardiac contractility by inhibition of voltage-operated calcium channels on vascular smooth muscle cells and cardiomyocytes. J Pharmacol Exp Ther. 2013 Jun;345(3):383-92. PMID: 23532933.

 

Sertel S, Fu Y, Zu Y, et al. Molecular docking and pharmacogenomics of vinca alkaloids and their monomeric precursors, vindoline and catharanthine. Biochem Pharmacol. 2011 Mar 15;81(6):723-35. PMID: 21219884.

" Not dangerous goods.

LKT C0378 Catharanthine Tartrate 100 mg 351 Alkaloid found in Catharanthus, precursor in synthesis of vinca alkaloids; voltage-gated Ca2+ channel blocker. 3,4-Didehydroibogamine-18-carboxylic acid methyl ester Catharanthine ≥97% 486.52 C21H24N2O2 C4H6O6 CCC1=CC2CC3(C1N(C2)CCC4=C3NC5=CC=CC=C45)C(=O)OC.C(C(C(=O)O)O)(C(=O)O)O Very hygroscopic. Ambient 4°C Soluble in ethanol. "Munigunti R, Becker K, Brun R, et al. Determination of antiplasmodial activity and binding affinity of selected natural products towards PfTrxR and PfGR. Nat Prod Commun. 2013 Aug;8(8):1135-6. PMID: 24079187.

 

Jadhav A, Liang W, Papageorgiou PC, et al. Catharanthine dilates small mesenteric arteries and decreases heart rate and cardiac contractility by inhibition of voltage-operated calcium channels on vascular smooth muscle cells and cardiomyocytes. J Pharmacol Exp Ther. 2013 Jun;345(3):383-92. PMID: 23532933.

 

Sertel S, Fu Y, Zu Y, et al. Molecular docking and pharmacogenomics of vinca alkaloids and their monomeric precursors, vindoline and catharanthine. Biochem Pharmacol. 2011 Mar 15;81(6):723-35. PMID: 21219884.

" Not dangerous goods.

LKT C0378 Catharanthine Tartrate 500 mg 1189.1 Alkaloid found in Catharanthus, precursor in synthesis of vinca alkaloids; voltage-gated Ca2+ channel blocker. 3,4-Didehydroibogamine-18-carboxylic acid methyl ester Catharanthine ≥97% 486.52 C21H24N2O2 C4H6O6 CCC1=CC2CC3(C1N(C2)CCC4=C3NC5=CC=CC=C45)C(=O)OC.C(C(C(=O)O)O)(C(=O)O)O Very hygroscopic. Ambient 4°C Soluble in ethanol. "Munigunti R, Becker K, Brun R, et al. Determination of antiplasmodial activity and binding affinity of selected natural products towards PfTrxR and PfGR. Nat Prod Commun. 2013 Aug;8(8):1135-6. PMID: 24079187.

 

Jadhav A, Liang W, Papageorgiou PC, et al. Catharanthine dilates small mesenteric arteries and decreases heart rate and cardiac contractility by inhibition of voltage-operated calcium channels on vascular smooth muscle cells and cardiomyocytes. J Pharmacol Exp Ther. 2013 Jun;345(3):383-92. PMID: 23532933.

 

Sertel S, Fu Y, Zu Y, et al. Molecular docking and pharmacogenomics of vinca alkaloids and their monomeric precursors, vindoline and catharanthine. Biochem Pharmacol. 2011 Mar 15;81(6):723-35. PMID: 21219884.

" Not dangerous goods.

LKT C0379 Catch-Relaxing Peptide 1 mg 72.1 Peptide, found in molluscs; BK/SK K+ channel modulator. CARP ≥95% 830.13 C36H67N11O7S2 Ambient -20°C "Fujiwara-Sakata M, Kobayashi M. Neuropeptides regulate the cardiac activity of a prosobranch mollusk, Rapana thomasiana. Cell Tissue Res. 1992 Aug;269(2):241-7. PMID: 1423492.

 

Kiss T. Catch-relaxing peptide (CARP) decreases the Ca-permeability of snail neuronal membrane. Experientia. 1988 Dec 1;44(11-12):998-1000. PMID: 2848713.

 

Hirata T, Kubota I, Takabatake I, et al. Catch-relaxing peptide isolated from Mytilus pedal ganglia. Brain Res. 1987 Oct 6;422(2):374-6. PMID: 3676797.

"

LKT C0379 Catch-Relaxing Peptide 2 mg 123.1 Peptide, found in molluscs; BK/SK K+ channel modulator. CARP ≥95% 830.13 C36H67N11O7S2 Ambient -20°C "Fujiwara-Sakata M, Kobayashi M. Neuropeptides regulate the cardiac activity of a prosobranch mollusk, Rapana thomasiana. Cell Tissue Res. 1992 Aug;269(2):241-7. PMID: 1423492.

 

Kiss T. Catch-relaxing peptide (CARP) decreases the Ca-permeability of snail neuronal membrane. Experientia. 1988 Dec 1;44(11-12):998-1000. PMID: 2848713.

 

Hirata T, Kubota I, Takabatake I, et al. Catch-relaxing peptide isolated from Mytilus pedal ganglia. Brain Res. 1987 Oct 6;422(2):374-6. PMID: 3676797.

"

LKT C0379 Catch-Relaxing Peptide 5 mg 216.1 Peptide, found in molluscs; BK/SK K+ channel modulator. CARP ≥95% 830.13 C36H67N11O7S2 Ambient -20°C "Fujiwara-Sakata M, Kobayashi M. Neuropeptides regulate the cardiac activity of a prosobranch mollusk, Rapana thomasiana. Cell Tissue Res. 1992 Aug;269(2):241-7. PMID: 1423492.

 

Kiss T. Catch-relaxing peptide (CARP) decreases the Ca-permeability of snail neuronal membrane. Experientia. 1988 Dec 1;44(11-12):998-1000. PMID: 2848713.

 

Hirata T, Kubota I, Takabatake I, et al. Catch-relaxing peptide isolated from Mytilus pedal ganglia. Brain Res. 1987 Oct 6;422(2):374-6. PMID: 3676797.

"

LKT V1769 Verapamil Hydrochloride 1 g 40.7 L-type Ca2+ channel blocker. α-[3-[[2-(3,4-Dimethoxyphenyl)ethyl]methylamino]- propyl]-3,4-dimethoxy-α-(1-methylethyl)benzene- acetonitrile Arpamyl; Berkatens; Calan; Cardiagutt; Cordilox; Dignover; Geangin; Univer; Veraptin; Verexamil 152-11-4 ≥98% 491.07 C27H38N2O4 CC(C)C(CCCN(C)CCC1=CC(=C(C=C1)OC)OC)(C#N)C2=CC(=C(C=C2)OC)OC.Cl Ambient Ambient Soluble in water, propylene glycol, methanol, or methylene chloride. "Flynn JT, Pasko DA. Calcium channel blockers: pharmacology and place in therapy of pediatric hypertension. Pediatr Nephrol. 2000 Dec;15(3-4):302-16. PMID: 11149130.

 

Pepine CJ. The role of calcium antagonists in ischaemic heart disease. Eur Heart J. 1995 Aug;16 Suppl H:19-24. PMID: 8846801.

" T "UN number: 2811     Class:  6.1     Packing group:  III

Proper shipping name:  Toxic solids, organic, n.o.s.(Verapamil hydrochloride)

Reportable Quantity (RQ):

Marine pollutant:  No     Poison inhalation hazard:  No. "

LKT V1769 Verapamil Hydrochloride 5 g 122.3 L-type Ca2+ channel blocker. α-[3-[[2-(3,4-Dimethoxyphenyl)ethyl]methylamino]- propyl]-3,4-dimethoxy-α-(1-methylethyl)benzene- acetonitrile Arpamyl; Berkatens; Calan; Cardiagutt; Cordilox; Dignover; Geangin; Univer; Veraptin; Verexamil 152-11-4 ≥98% 491.07 C27H38N2O4 CC(C)C(CCCN(C)CCC1=CC(=C(C=C1)OC)OC)(C#N)C2=CC(=C(C=C2)OC)OC.Cl Ambient Ambient Soluble in water, propylene glycol, methanol, or methylene chloride. "Flynn JT, Pasko DA. Calcium channel blockers: pharmacology and place in therapy of pediatric hypertension. Pediatr Nephrol. 2000 Dec;15(3-4):302-16. PMID: 11149130.

 

Pepine CJ. The role of calcium antagonists in ischaemic heart disease. Eur Heart J. 1995 Aug;16 Suppl H:19-24. PMID: 8846801.

" T "UN number: 2811     Class:  6.1     Packing group:  III

Proper shipping name:  Toxic solids, organic, n.o.s.(Verapamil hydrochloride)

Reportable Quantity (RQ):

Marine pollutant:  No     Poison inhalation hazard:  No. "

LKT C0476 CB-TH 1 mg 234.2 Peptide, cecropin B-thanatin conjugate. ≥95% 3205.9 C138H230N46O34S4 Ambient -20°C Hongbiao W, Baolong N, Mengkui X, et al. Biological activities of cecropin B-thanatin hybrid peptides. J Pept Res. 2005 Dec;66(6):382-6. PMID: 16316454. Not dangerous goods.

LKT C0476 CB-TH 2 mg 396.1 Peptide, cecropin B-thanatin conjugate. ≥95% 3205.9 C138H230N46O34S4 Ambient -20°C Hongbiao W, Baolong N, Mengkui X, et al. Biological activities of cecropin B-thanatin hybrid peptides. J Pept Res. 2005 Dec;66(6):382-6. PMID: 16316454. Not dangerous goods.

LKT C0476 CB-TH 5 mg 702 Peptide, cecropin B-thanatin conjugate. ≥95% 3205.9 C138H230N46O34S4 Ambient -20°C Hongbiao W, Baolong N, Mengkui X, et al. Biological activities of cecropin B-thanatin hybrid peptides. J Pept Res. 2005 Dec;66(6):382-6. PMID: 16316454. Not dangerous goods.

LKT C1600 Carcinoembryonic Antigen (605-613) 1 mg 234.2 Carcinoembryonic antigen epitope. CEA ≥95% 964.09 C43H69N11O14 Ambient -20°C "Hou Y, Kavanagh B, Fong L. Distinct CD8+ T cell repertoires primed with agonist and native peptides derived from a tumor-associated antigen. J Immunol. 2008 Feb 1;180(3):1526-34. PMID: 18209048.

 

Tosi D, Valenti R, Cova A, et al. Role of cross-talk between IFN-alpha-induced monocyte-derived dendritic cells and NK cells in priming CD8+ T cell responses against human tumor antigens. J Immunol. 2004 May 1;172(9):5363-70. PMID: 15100276.

" Not dangerous goods.

LKT C1600 Carcinoembryonic Antigen (605-613) 2 mg 396.1 Carcinoembryonic antigen epitope. CEA ≥95% 964.09 C43H69N11O14 Ambient -20°C "Hou Y, Kavanagh B, Fong L. Distinct CD8+ T cell repertoires primed with agonist and native peptides derived from a tumor-associated antigen. J Immunol. 2008 Feb 1;180(3):1526-34. PMID: 18209048.

 

Tosi D, Valenti R, Cova A, et al. Role of cross-talk between IFN-alpha-induced monocyte-derived dendritic cells and NK cells in priming CD8+ T cell responses against human tumor antigens. J Immunol. 2004 May 1;172(9):5363-70. PMID: 15100276.

" Not dangerous goods.

LKT C1600 Carcinoembryonic Antigen (605-613) 5 mg 702 Carcinoembryonic antigen epitope. CEA ≥95% 964.09 C43H69N11O14 Ambient -20°C "Hou Y, Kavanagh B, Fong L. Distinct CD8+ T cell repertoires primed with agonist and native peptides derived from a tumor-associated antigen. J Immunol. 2008 Feb 1;180(3):1526-34. PMID: 18209048.

 

Tosi D, Valenti R, Cova A, et al. Role of cross-talk between IFN-alpha-induced monocyte-derived dendritic cells and NK cells in priming CD8+ T cell responses against human tumor antigens. J Immunol. 2004 May 1;172(9):5363-70. PMID: 15100276.

" Not dangerous goods.

LKT C1601 Carcinoembryonic Antigen (605-613) analog 1 mg 72.1 Carcinoembryonic antigen epitope analog. CEA ≥95% 965.08 C43H68N10O15 Ambient -20°C "Hou Y, Kavanagh B, Fong L. Distinct CD8+ T cell repertoires primed with agonist and native peptides derived from a tumor-associated antigen. J Immunol. 2008 Feb 1;180(3):1526-34. PMID: 18209048.

 

Tosi D, Valenti R, Cova A, et al. Role of cross-talk between IFN-alpha-induced monocyte-derived dendritic cells and NK cells in priming CD8+ T cell responses against human tumor antigens. J Immunol. 2004 May 1;172(9):5363-70. PMID: 15100276.

" Not dangerous goods.

LKT C1601 Carcinoembryonic Antigen (605-613) analog 2 mg 123.1 Carcinoembryonic antigen epitope analog. CEA ≥95% 965.08 C43H68N10O15 Ambient -20°C "Hou Y, Kavanagh B, Fong L. Distinct CD8+ T cell repertoires primed with agonist and native peptides derived from a tumor-associated antigen. J Immunol. 2008 Feb 1;180(3):1526-34. PMID: 18209048.

 

Tosi D, Valenti R, Cova A, et al. Role of cross-talk between IFN-alpha-induced monocyte-derived dendritic cells and NK cells in priming CD8+ T cell responses against human tumor antigens. J Immunol. 2004 May 1;172(9):5363-70. PMID: 15100276.

" Not dangerous goods.

LKT C1601 Carcinoembryonic Antigen (605-613) analog 5 mg 216.1 Carcinoembryonic antigen epitope analog. CEA ≥95% 965.08 C43H68N10O15 Ambient -20°C "Hou Y, Kavanagh B, Fong L. Distinct CD8+ T cell repertoires primed with agonist and native peptides derived from a tumor-associated antigen. J Immunol. 2008 Feb 1;180(3):1526-34. PMID: 18209048.

 

Tosi D, Valenti R, Cova A, et al. Role of cross-talk between IFN-alpha-induced monocyte-derived dendritic cells and NK cells in priming CD8+ T cell responses against human tumor antigens. J Immunol. 2004 May 1;172(9):5363-70. PMID: 15100276.

" Not dangerous goods.

LKT C1609 Cecropin B 1 mg 348 Antimicrobial peptide found in Hyalophora cecropia and Bombyx mori. 80451-05-4 ≥95% 3834.76 C176H302N52O41S CCC(C)C(C(=O)NC(C(C)C)C(=O)NC(CCCCN)C(=O)NC(C)C(=O)NCC(=O)N1CCCC1C(=O)NC(C)C(=O)NC(C(C)CC)C(=O)NC(C)C(=O)NC(C(C)C)C(=O)NC(CC(C)C)C(=O)NCC(=O)NC(CCC(=O)O)C(=O)NC(C)C(=O)NC(CCCCN)C(=O)NC(C)C(=O)NC(CC(C)C)C(=O)N)NC(=O)CNC(=O)C(CC(=O)N)NC(=O)C(CCCNC(=N)N)NC(=O)C(C(C)CC)NC(=O)C(CC(=O)N)NC(=O)C(CCCNC(=N)N)NC(=O)CNC(=O)C(CCSC)NC(=O)C(CCCCN)NC(=O)C(CCC(=O)O)NC(=O)C(C(C)CC)NC(=O)C(CCCCN)NC(=O)C(CCCCN)NC(=O)C(CC2=CC=CC=C2)NC(=O)C(C(C)C)NC(=O)C(CCCCN)NC(=O)C(CC3=CNC4=CC=CC=C43)NC(=O)C(CCCCN)N Ambient -20°C "Hu H, Wang C, Guo X, et al. Broad activity against porcine bacterial pathogens displayed by two insect antimicrobial peptides moricin and cecropin B. Mol Cells. 2013 Feb;35(2):106-14. PMID: 23456332.

 

Luo CC, Yin DY, Gao XJ, et al. Goat mammary gland expression of Cecropin B to inhibit bacterial pathogens causing mastitis. Anim Biotechnol. 2013 Jan;24(1):66-78. PMID: 23394371.

 

Wang X, Zhu M, Yang G, et al. Expression of cecropin B in Pichia pastoris and its bioactivity in vitro. Exp Ther Med. 2011 Jul;2(4):655-660. PMID: 22977556.

" Not dangerous goods.

LKT C1609 Cecropin B 2 mg 591 Antimicrobial peptide found in Hyalophora cecropia and Bombyx mori. 80451-05-4 ≥95% 3834.76 C176H302N52O41S CCC(C)C(C(=O)NC(C(C)C)C(=O)NC(CCCCN)C(=O)NC(C)C(=O)NCC(=O)N1CCCC1C(=O)NC(C)C(=O)NC(C(C)CC)C(=O)NC(C)C(=O)NC(C(C)C)C(=O)NC(CC(C)C)C(=O)NCC(=O)NC(CCC(=O)O)C(=O)NC(C)C(=O)NC(CCCCN)C(=O)NC(C)C(=O)NC(CC(C)C)C(=O)N)NC(=O)CNC(=O)C(CC(=O)N)NC(=O)C(CCCNC(=N)N)NC(=O)C(C(C)CC)NC(=O)C(CC(=O)N)NC(=O)C(CCCNC(=N)N)NC(=O)CNC(=O)C(CCSC)NC(=O)C(CCCCN)NC(=O)C(CCC(=O)O)NC(=O)C(C(C)CC)NC(=O)C(CCCCN)NC(=O)C(CCCCN)NC(=O)C(CC2=CC=CC=C2)NC(=O)C(C(C)C)NC(=O)C(CCCCN)NC(=O)C(CC3=CNC4=CC=CC=C43)NC(=O)C(CCCCN)N Ambient -20°C "Hu H, Wang C, Guo X, et al. Broad activity against porcine bacterial pathogens displayed by two insect antimicrobial peptides moricin and cecropin B. Mol Cells. 2013 Feb;35(2):106-14. PMID: 23456332.

 

Luo CC, Yin DY, Gao XJ, et al. Goat mammary gland expression of Cecropin B to inhibit bacterial pathogens causing mastitis. Anim Biotechnol. 2013 Jan;24(1):66-78. PMID: 23394371.

 

Wang X, Zhu M, Yang G, et al. Expression of cecropin B in Pichia pastoris and its bioactivity in vitro. Exp Ther Med. 2011 Jul;2(4):655-660. PMID: 22977556.

" Not dangerous goods.

LKT C1609 Cecropin B 5 mg 1043.9 Antimicrobial peptide found in Hyalophora cecropia and Bombyx mori. 80451-05-4 ≥95% 3834.76 C176H302N52O41S CCC(C)C(C(=O)NC(C(C)C)C(=O)NC(CCCCN)C(=O)NC(C)C(=O)NCC(=O)N1CCCC1C(=O)NC(C)C(=O)NC(C(C)CC)C(=O)NC(C)C(=O)NC(C(C)C)C(=O)NC(CC(C)C)C(=O)NCC(=O)NC(CCC(=O)O)C(=O)NC(C)C(=O)NC(CCCCN)C(=O)NC(C)C(=O)NC(CC(C)C)C(=O)N)NC(=O)CNC(=O)C(CC(=O)N)NC(=O)C(CCCNC(=N)N)NC(=O)C(C(C)CC)NC(=O)C(CC(=O)N)NC(=O)C(CCCNC(=N)N)NC(=O)CNC(=O)C(CCSC)NC(=O)C(CCCCN)NC(=O)C(CCC(=O)O)NC(=O)C(C(C)CC)NC(=O)C(CCCCN)NC(=O)C(CCCCN)NC(=O)C(CC2=CC=CC=C2)NC(=O)C(C(C)C)NC(=O)C(CCCCN)NC(=O)C(CC3=CNC4=CC=CC=C43)NC(=O)C(CCCCN)N Ambient -20°C "Hu H, Wang C, Guo X, et al. Broad activity against porcine bacterial pathogens displayed by two insect antimicrobial peptides moricin and cecropin B. Mol Cells. 2013 Feb;35(2):106-14. PMID: 23456332.

 

Luo CC, Yin DY, Gao XJ, et al. Goat mammary gland expression of Cecropin B to inhibit bacterial pathogens causing mastitis. Anim Biotechnol. 2013 Jan;24(1):66-78. PMID: 23394371.

 

Wang X, Zhu M, Yang G, et al. Expression of cecropin B in Pichia pastoris and its bioactivity in vitro. Exp Ther Med. 2011 Jul;2(4):655-660. PMID: 22977556.

" Not dangerous goods.

LKT C1619 CEF3 1 mg 72.1 Peptide, vSrc-induced cytokine. ≥95% 911.12 C42H74N10O12 Ambient -20°C "Bojović B, Rodrigues N, Dehbi M, et al. Multiple signaling pathways control the activation of the CEF-4/9E3 cytokine gene by pp60v-src. J Biol Chem. 1996 Sep 13;271(37):22528-37. PMID: 8798420.

 

Gonneville L, Martins TJ, Bédard PA. Complex expression pattern of the CEF-4 cytokine in transformed and mitogenically stimulated cells. Oncogene. 1991 Oct;6(10):1825-33. PMID: 1656364.

 

Simmons DL, Levy DB, Yannoni Y, et al. Identification of a phorbol ester-repressible v-src-inducible gene. Proc Natl Acad Sci U S A. 1989 Feb;86(4):1178-82. PMID: 2537491.

"

LKT C1619 CEF3 2 mg 123.1 Peptide, vSrc-induced cytokine. ≥95% 911.12 C42H74N10O12 Ambient -20°C "Bojović B, Rodrigues N, Dehbi M, et al. Multiple signaling pathways control the activation of the CEF-4/9E3 cytokine gene by pp60v-src. J Biol Chem. 1996 Sep 13;271(37):22528-37. PMID: 8798420.

 

Gonneville L, Martins TJ, Bédard PA. Complex expression pattern of the CEF-4 cytokine in transformed and mitogenically stimulated cells. Oncogene. 1991 Oct;6(10):1825-33. PMID: 1656364.

 

Simmons DL, Levy DB, Yannoni Y, et al. Identification of a phorbol ester-repressible v-src-inducible gene. Proc Natl Acad Sci U S A. 1989 Feb;86(4):1178-82. PMID: 2537491.

"

LKT C1619 CEF3 5 mg 216.1 Peptide, vSrc-induced cytokine. ≥95% 911.12 C42H74N10O12 Ambient -20°C "Bojović B, Rodrigues N, Dehbi M, et al. Multiple signaling pathways control the activation of the CEF-4/9E3 cytokine gene by pp60v-src. J Biol Chem. 1996 Sep 13;271(37):22528-37. PMID: 8798420.

 

Gonneville L, Martins TJ, Bédard PA. Complex expression pattern of the CEF-4 cytokine in transformed and mitogenically stimulated cells. Oncogene. 1991 Oct;6(10):1825-33. PMID: 1656364.

 

Simmons DL, Levy DB, Yannoni Y, et al. Identification of a phorbol ester-repressible v-src-inducible gene. Proc Natl Acad Sci U S A. 1989 Feb;86(4):1178-82. PMID: 2537491.

"

LKT C1620 Ceftiofur Hydrochloride 500 mg 65.6 β-lactam; penicillin binding protein inhibitor. "5-Thia-1-azabicyclo(4.2.0)oct-2-ene-2-carboxylic acid, 7-

(((2-amino-4-thiazolyl)(methoxyimino)acetyl)amino)-3-(((2-

furanylcarbonyl)thio)methyl)-8-oxo-, (6R-(6alpha,7beta(Z)))- 

" "Excenel;  Ceftiofurum;  Vetranal

" 104010-37-9 ≥90% 560.02 C19H17N5O7S3 HCl CON=C(C1=CSC(=N1)N)C(=O)NC2C3N(C2=O)C(=C(CS3)CSC(=O)C4=CC=CO4)C(=O)[O-].[Na+] Ambient 4°C Insoluble in water "Li X, Zheng W, Machesky ML, et al. Degradation kinetics and mechanism of antibiotic ceftiofur in recycled water derived from a beef farm. J Agric Food Chem. 2011 Sep 28;59(18):10176-81. PMID: 21863813.

 

Ci X, Li H, Song Y, et al. Ceftiofur regulates LPS-induced production of cytokines and improves LPS-induced survival rate in mice. Inflammation. 2008 Dec;31(6):422-7. PMID: 18989766.

" None Not dangerous goods.

LKT C1620 Ceftiofur Hydrochloride 1 g 93.8 β-lactam; penicillin binding protein inhibitor. "5-Thia-1-azabicyclo(4.2.0)oct-2-ene-2-carboxylic acid, 7-

(((2-amino-4-thiazolyl)(methoxyimino)acetyl)amino)-3-(((2-

furanylcarbonyl)thio)methyl)-8-oxo-, (6R-(6alpha,7beta(Z)))- 

" "Excenel;  Ceftiofurum;  Vetranal

" 104010-37-9 ≥90% 560.02 C19H17N5O7S3 HCl CON=C(C1=CSC(=N1)N)C(=O)NC2C3N(C2=O)C(=C(CS3)CSC(=O)C4=CC=CO4)C(=O)[O-].[Na+] Ambient 4°C Insoluble in water "Li X, Zheng W, Machesky ML, et al. Degradation kinetics and mechanism of antibiotic ceftiofur in recycled water derived from a beef farm. J Agric Food Chem. 2011 Sep 28;59(18):10176-81. PMID: 21863813.

 

Ci X, Li H, Song Y, et al. Ceftiofur regulates LPS-induced production of cytokines and improves LPS-induced survival rate in mice. Inflammation. 2008 Dec;31(6):422-7. PMID: 18989766.

" None Not dangerous goods.

LKT C1620 Ceftiofur Hydrochloride 5 g 328.1 β-lactam; penicillin binding protein inhibitor. "5-Thia-1-azabicyclo(4.2.0)oct-2-ene-2-carboxylic acid, 7-

(((2-amino-4-thiazolyl)(methoxyimino)acetyl)amino)-3-(((2-

furanylcarbonyl)thio)methyl)-8-oxo-, (6R-(6alpha,7beta(Z)))- 

" "Excenel;  Ceftiofurum;  Vetranal

" 104010-37-9 ≥90% 560.02 C19H17N5O7S3 HCl CON=C(C1=CSC(=N1)N)C(=O)NC2C3N(C2=O)C(=C(CS3)CSC(=O)C4=CC=CO4)C(=O)[O-].[Na+] Ambient 4°C Insoluble in water "Li X, Zheng W, Machesky ML, et al. Degradation kinetics and mechanism of antibiotic ceftiofur in recycled water derived from a beef farm. J Agric Food Chem. 2011 Sep 28;59(18):10176-81. PMID: 21863813.

 

Ci X, Li H, Song Y, et al. Ceftiofur regulates LPS-induced production of cytokines and improves LPS-induced survival rate in mice. Inflammation. 2008 Dec;31(6):422-7. PMID: 18989766.

" None Not dangerous goods.

LKT V0376 Vatalanib Dihydrochloride 5 mg 163.2 VEGFR inhibitor. ≥98% 419.73 C20H15ClN4 2HCl C1=CC=C2C(=C1)C(=NN=C2NC3=CC=C(C=C3)Cl)CC4=CC=NC=C4.Cl.Cl Ambient Ambient "Gupta P, Mulkey F, Hasserjian RP, et al. A phase II study of the oral VEGF receptor tyrosine kinase inhibitor vatalanib (PTK787/ZK222584) in myelodysplastic syndrome: Cancer and Leukemia Group B study 10105 (Alliance). Invest New Drugs. 2013 Oct;31(5):1311-20. PMID: 23700288.

 

Liu S, Xu C, Li G, et al. Vatalanib decrease the positive interaction of VEGF receptor-2 and P2X2/3 receptor in chronic constriction injury rats. Neurochem Int. 2012 May;60(6):565-72. PMID: 22361062.

 

Gauler TC, Besse B, Mauguen A, et al. Phase II trial of PTK787/ZK 222584 (vatalanib) administered orally once-daily or in two divided daily doses as second-line monotherapy in relapsed or progressing patients with stage IIIB/IV non-small-cell lung cancer (NSCLC). Ann Oncol. 2012 Mar;23(3):678-87. PMID: 21617019.

 

Hlushchuk R, Riesterer O, Baum O, et al. Tumor recovery by angiogenic switch from sprouting to intussusceptive angiogenesis after treatment with PTK787/ZK222584 or ionizing radiation. Am J Pathol. 2008 Oct;173(4):1173-85. PMID: 18787105.

 

Solorzano CC, Baker CH, Bruns CJ, et al. Inhibition of growth and metastasis of human pancreatic cancer growing in nude mice by PTK 787/ZK222584, an inhibitor of the vascular endothelial growth factor receptor tyrosine kinases. Cancer Biother Radiopharm. 2001 Oct;16(5):359-70. PMID: 11776753.

"

LKT V0376 Vatalanib Dihydrochloride 10 mg 271.7 VEGFR inhibitor. ≥98% 419.73 C20H15ClN4 2HCl C1=CC=C2C(=C1)C(=NN=C2NC3=CC=C(C=C3)Cl)CC4=CC=NC=C4.Cl.Cl Ambient Ambient "Gupta P, Mulkey F, Hasserjian RP, et al. A phase II study of the oral VEGF receptor tyrosine kinase inhibitor vatalanib (PTK787/ZK222584) in myelodysplastic syndrome: Cancer and Leukemia Group B study 10105 (Alliance). Invest New Drugs. 2013 Oct;31(5):1311-20. PMID: 23700288.

 

Liu S, Xu C, Li G, et al. Vatalanib decrease the positive interaction of VEGF receptor-2 and P2X2/3 receptor in chronic constriction injury rats. Neurochem Int. 2012 May;60(6):565-72. PMID: 22361062.

 

Gauler TC, Besse B, Mauguen A, et al. Phase II trial of PTK787/ZK 222584 (vatalanib) administered orally once-daily or in two divided daily doses as second-line monotherapy in relapsed or progressing patients with stage IIIB/IV non-small-cell lung cancer (NSCLC). Ann Oncol. 2012 Mar;23(3):678-87. PMID: 21617019.

 

Hlushchuk R, Riesterer O, Baum O, et al. Tumor recovery by angiogenic switch from sprouting to intussusceptive angiogenesis after treatment with PTK787/ZK222584 or ionizing radiation. Am J Pathol. 2008 Oct;173(4):1173-85. PMID: 18787105.

 

Solorzano CC, Baker CH, Bruns CJ, et al. Inhibition of growth and metastasis of human pancreatic cancer growing in nude mice by PTK 787/ZK222584, an inhibitor of the vascular endothelial growth factor receptor tyrosine kinases. Cancer Biother Radiopharm. 2001 Oct;16(5):359-70. PMID: 11776753.

"

LKT V0376 Vatalanib Dihydrochloride 25 mg 502.8 VEGFR inhibitor. ≥98% 419.73 C20H15ClN4 2HCl C1=CC=C2C(=C1)C(=NN=C2NC3=CC=C(C=C3)Cl)CC4=CC=NC=C4.Cl.Cl Ambient Ambient "Gupta P, Mulkey F, Hasserjian RP, et al. A phase II study of the oral VEGF receptor tyrosine kinase inhibitor vatalanib (PTK787/ZK222584) in myelodysplastic syndrome: Cancer and Leukemia Group B study 10105 (Alliance). Invest New Drugs. 2013 Oct;31(5):1311-20. PMID: 23700288.

 

Liu S, Xu C, Li G, et al. Vatalanib decrease the positive interaction of VEGF receptor-2 and P2X2/3 receptor in chronic constriction injury rats. Neurochem Int. 2012 May;60(6):565-72. PMID: 22361062.

 

Gauler TC, Besse B, Mauguen A, et al. Phase II trial of PTK787/ZK 222584 (vatalanib) administered orally once-daily or in two divided daily doses as second-line monotherapy in relapsed or progressing patients with stage IIIB/IV non-small-cell lung cancer (NSCLC). Ann Oncol. 2012 Mar;23(3):678-87. PMID: 21617019.

 

Hlushchuk R, Riesterer O, Baum O, et al. Tumor recovery by angiogenic switch from sprouting to intussusceptive angiogenesis after treatment with PTK787/ZK222584 or ionizing radiation. Am J Pathol. 2008 Oct;173(4):1173-85. PMID: 18787105.

 

Solorzano CC, Baker CH, Bruns CJ, et al. Inhibition of growth and metastasis of human pancreatic cancer growing in nude mice by PTK 787/ZK222584, an inhibitor of the vascular endothelial growth factor receptor tyrosine kinases. Cancer Biother Radiopharm. 2001 Oct;16(5):359-70. PMID: 11776753.

"

LKT C1621 CEF4 1 mg 72.1 Peptide, vSrc-induced cytokine. ≥95% 1148.42 C53H93N15O13 Ambient -20°C "Bojović B, Rodrigues N, Dehbi M, et al. Multiple signaling pathways control the activation of the CEF-4/9E3 cytokine gene by pp60v-src. J Biol Chem. 1996 Sep 13;271(37):22528-37. PMID: 8798420.

 

Gonneville L, Martins TJ, Bédard PA. Complex expression pattern of the CEF-4 cytokine in transformed and mitogenically stimulated cells. Oncogene. 1991 Oct;6(10):1825-33. PMID: 1656364.

 

Simmons DL, Levy DB, Yannoni Y, et al. Identification of a phorbol ester-repressible v-src-inducible gene. Proc Natl Acad Sci U S A. 1989 Feb;86(4):1178-82. PMID: 2537491.

" Not dangerous goods.

LKT C1621 CEF4 2 mg 123.1 Peptide, vSrc-induced cytokine. ≥95% 1148.42 C53H93N15O13 Ambient -20°C "Bojović B, Rodrigues N, Dehbi M, et al. Multiple signaling pathways control the activation of the CEF-4/9E3 cytokine gene by pp60v-src. J Biol Chem. 1996 Sep 13;271(37):22528-37. PMID: 8798420.

 

Gonneville L, Martins TJ, Bédard PA. Complex expression pattern of the CEF-4 cytokine in transformed and mitogenically stimulated cells. Oncogene. 1991 Oct;6(10):1825-33. PMID: 1656364.

 

Simmons DL, Levy DB, Yannoni Y, et al. Identification of a phorbol ester-repressible v-src-inducible gene. Proc Natl Acad Sci U S A. 1989 Feb;86(4):1178-82. PMID: 2537491.

" Not dangerous goods.

LKT C1621 CEF4 5 mg 216.1 Peptide, vSrc-induced cytokine. ≥95% 1148.42 C53H93N15O13 Ambient -20°C "Bojović B, Rodrigues N, Dehbi M, et al. Multiple signaling pathways control the activation of the CEF-4/9E3 cytokine gene by pp60v-src. J Biol Chem. 1996 Sep 13;271(37):22528-37. PMID: 8798420.

 

Gonneville L, Martins TJ, Bédard PA. Complex expression pattern of the CEF-4 cytokine in transformed and mitogenically stimulated cells. Oncogene. 1991 Oct;6(10):1825-33. PMID: 1656364.

 

Simmons DL, Levy DB, Yannoni Y, et al. Identification of a phorbol ester-repressible v-src-inducible gene. Proc Natl Acad Sci U S A. 1989 Feb;86(4):1178-82. PMID: 2537491.

" Not dangerous goods.

LKT C1622 CEF6 1 mg 72.1 Peptide, vSrc-induced cytokine. ≥95% 1051.28 C48H78N10O14S Ambient -20°C "Bojović B, Rodrigues N, Dehbi M, et al. Multiple signaling pathways control the activation of the CEF-4/9E3 cytokine gene by pp60v-src. J Biol Chem. 1996 Sep 13;271(37):22528-37. PMID: 8798420.

 

Gonneville L, Martins TJ, Bédard PA. Complex expression pattern of the CEF-4 cytokine in transformed and mitogenically stimulated cells. Oncogene. 1991 Oct;6(10):1825-33. PMID: 1656364.

 

Simmons DL, Levy DB, Yannoni Y, et al. Identification of a phorbol ester-repressible v-src-inducible gene. Proc Natl Acad Sci U S A. 1989 Feb;86(4):1178-82. PMID: 2537491.

" Not dangerous goods.

LKT C1622 CEF6 2 mg 123.1 Peptide, vSrc-induced cytokine. ≥95% 1051.28 C48H78N10O14S Ambient -20°C "Bojović B, Rodrigues N, Dehbi M, et al. Multiple signaling pathways control the activation of the CEF-4/9E3 cytokine gene by pp60v-src. J Biol Chem. 1996 Sep 13;271(37):22528-37. PMID: 8798420.

 

Gonneville L, Martins TJ, Bédard PA. Complex expression pattern of the CEF-4 cytokine in transformed and mitogenically stimulated cells. Oncogene. 1991 Oct;6(10):1825-33. PMID: 1656364.

 

Simmons DL, Levy DB, Yannoni Y, et al. Identification of a phorbol ester-repressible v-src-inducible gene. Proc Natl Acad Sci U S A. 1989 Feb;86(4):1178-82. PMID: 2537491.

" Not dangerous goods.

LKT C1622 CEF6 5 mg 216.1 Peptide, vSrc-induced cytokine. ≥95% 1051.28 C48H78N10O14S Ambient -20°C "Bojović B, Rodrigues N, Dehbi M, et al. Multiple signaling pathways control the activation of the CEF-4/9E3 cytokine gene by pp60v-src. J Biol Chem. 1996 Sep 13;271(37):22528-37. PMID: 8798420.

 

Gonneville L, Martins TJ, Bédard PA. Complex expression pattern of the CEF-4 cytokine in transformed and mitogenically stimulated cells. Oncogene. 1991 Oct;6(10):1825-33. PMID: 1656364.

 

Simmons DL, Levy DB, Yannoni Y, et al. Identification of a phorbol ester-repressible v-src-inducible gene. Proc Natl Acad Sci U S A. 1989 Feb;86(4):1178-82. PMID: 2537491.

" Not dangerous goods.

LKT C1623 CEF10 1 mg 72.1 Peptide, vSrc-induced cytokine. ≥95% 906.2 C39H71N9O11S Ambient -20°C "Bojović B, Rodrigues N, Dehbi M, et al. Multiple signaling pathways control the activation of the CEF-4/9E3 cytokine gene by pp60v-src. J Biol Chem. 1996 Sep 13;271(37):22528-37. PMID: 8798420.

 

Gonneville L, Martins TJ, Bédard PA. Complex expression pattern of the CEF-4 cytokine in transformed and mitogenically stimulated cells. Oncogene. 1991 Oct;6(10):1825-33. PMID: 1656364.

 

Simmons DL, Levy DB, Yannoni Y, et al. Identification of a phorbol ester-repressible v-src-inducible gene. Proc Natl Acad Sci U S A. 1989 Feb;86(4):1178-82. PMID: 2537491.

"

LKT C1623 CEF10 2 mg 123.1 Peptide, vSrc-induced cytokine. ≥95% 906.2 C39H71N9O11S Ambient -20°C "Bojović B, Rodrigues N, Dehbi M, et al. Multiple signaling pathways control the activation of the CEF-4/9E3 cytokine gene by pp60v-src. J Biol Chem. 1996 Sep 13;271(37):22528-37. PMID: 8798420.

 

Gonneville L, Martins TJ, Bédard PA. Complex expression pattern of the CEF-4 cytokine in transformed and mitogenically stimulated cells. Oncogene. 1991 Oct;6(10):1825-33. PMID: 1656364.

 

Simmons DL, Levy DB, Yannoni Y, et al. Identification of a phorbol ester-repressible v-src-inducible gene. Proc Natl Acad Sci U S A. 1989 Feb;86(4):1178-82. PMID: 2537491.

"

LKT C1623 CEF10 5 mg 216.1 Peptide, vSrc-induced cytokine. ≥95% 906.2 C39H71N9O11S Ambient -20°C "Bojović B, Rodrigues N, Dehbi M, et al. Multiple signaling pathways control the activation of the CEF-4/9E3 cytokine gene by pp60v-src. J Biol Chem. 1996 Sep 13;271(37):22528-37. PMID: 8798420.

 

Gonneville L, Martins TJ, Bédard PA. Complex expression pattern of the CEF-4 cytokine in transformed and mitogenically stimulated cells. Oncogene. 1991 Oct;6(10):1825-33. PMID: 1656364.

 

Simmons DL, Levy DB, Yannoni Y, et al. Identification of a phorbol ester-repressible v-src-inducible gene. Proc Natl Acad Sci U S A. 1989 Feb;86(4):1178-82. PMID: 2537491.

"

LKT C1627 Cefaclor Monohydrate 500 mg 115.5 β-lactam cephalosporin; penicillin binding protein inhibitor. (6R,7R)-7-[[(2R)-Aminophenylacetyl]amino]-3-chloro-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid monohydrate Alfacet; Ceclor; Distaclor; Panacef; Panoral 70356-03-5 ≥97% 385.83 C15H13ClN3O4S H2O C1C(=C(N2C(S1)C(C2=O)NC(=O)C(C3=CC=CC=C3)N)C(=O)O)Cl Ambient Ambient Soluble in water. Practically insoluble in methanol, chloroform and benzene. "Berti AD, Sakoulas G, Nizet V, et al. β-Lactam antibiotics targeting PBP1 selectively enhance daptomycin activity against methicillin-resistant Staphylococcus aureus. Antimicrob Agents Chemother. 2013 Oct;57(10):5005-12. PMID: 23896478.

 

Dabrowski MP, Stankiewicz W. Desirable and undesirable immunotropic effects of antibiotics: immunomodulating properties of cefaclor. J Chemother. 2001 Dec;13(6):615-20. PMID: 11806622.

 

Bozkurt A, Deniz M, Yegen BC. Cefaclor, a cephalosporin antibiotic, delays gastric emptying rate by a CCK-A receptor-mediated mechanism in the rat. Br J Pharmacol. 2000 Oct;131(3):399-404. PMID: 11015288.

" Not dangerous goods.

LKT C1627 Cefaclor Monohydrate 1 g 184.8 β-lactam cephalosporin; penicillin binding protein inhibitor. (6R,7R)-7-[[(2R)-Aminophenylacetyl]amino]-3-chloro-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid monohydrate Alfacet; Ceclor; Distaclor; Panacef; Panoral 70356-03-5 ≥97% 385.83 C15H13ClN3O4S H2O C1C(=C(N2C(S1)C(C2=O)NC(=O)C(C3=CC=CC=C3)N)C(=O)O)Cl Ambient Ambient Soluble in water. Practically insoluble in methanol, chloroform and benzene. "Berti AD, Sakoulas G, Nizet V, et al. β-Lactam antibiotics targeting PBP1 selectively enhance daptomycin activity against methicillin-resistant Staphylococcus aureus. Antimicrob Agents Chemother. 2013 Oct;57(10):5005-12. PMID: 23896478.

 

Dabrowski MP, Stankiewicz W. Desirable and undesirable immunotropic effects of antibiotics: immunomodulating properties of cefaclor. J Chemother. 2001 Dec;13(6):615-20. PMID: 11806622.

 

Bozkurt A, Deniz M, Yegen BC. Cefaclor, a cephalosporin antibiotic, delays gastric emptying rate by a CCK-A receptor-mediated mechanism in the rat. Br J Pharmacol. 2000 Oct;131(3):399-404. PMID: 11015288.

" Not dangerous goods.

LKT C1627 Cefaclor Monohydrate 5 g 693.2 β-lactam cephalosporin; penicillin binding protein inhibitor. (6R,7R)-7-[[(2R)-Aminophenylacetyl]amino]-3-chloro-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid monohydrate Alfacet; Ceclor; Distaclor; Panacef; Panoral 70356-03-5 ≥97% 385.83 C15H13ClN3O4S H2O C1C(=C(N2C(S1)C(C2=O)NC(=O)C(C3=CC=CC=C3)N)C(=O)O)Cl Ambient Ambient Soluble in water. Practically insoluble in methanol, chloroform and benzene. "Berti AD, Sakoulas G, Nizet V, et al. β-Lactam antibiotics targeting PBP1 selectively enhance daptomycin activity against methicillin-resistant Staphylococcus aureus. Antimicrob Agents Chemother. 2013 Oct;57(10):5005-12. PMID: 23896478.

 

Dabrowski MP, Stankiewicz W. Desirable and undesirable immunotropic effects of antibiotics: immunomodulating properties of cefaclor. J Chemother. 2001 Dec;13(6):615-20. PMID: 11806622.

 

Bozkurt A, Deniz M, Yegen BC. Cefaclor, a cephalosporin antibiotic, delays gastric emptying rate by a CCK-A receptor-mediated mechanism in the rat. Br J Pharmacol. 2000 Oct;131(3):399-404. PMID: 11015288.

" Not dangerous goods.

LKT V0352 Vandetanib 5 mg 108.9 RET, EGFR, VEGFR2 inhibitor. ZD6474 443913-73-3 ≥98% 475.35 C22H24BrFN4O2 CN1CCC(CC1)COC2=C(C=C3C(=C2)N=CN=C3NC4=C(C=C(C=C4)Br)F)OC Ambient Ambient "Liu Y, Liu Y, Fan ZW, et al. Meta-analysis of the risks of hypertension and QTc prolongation in patients with advanced non-small cell lung cancer who were receiving vandetanib. Eur J Clin Pharmacol. 2015 May;71(5):541-7. PMID: 25753291

 

Shen J, Zheng H, Ruan J, et al. Autophagy inhibition induces enhanced proapoptotic effects of ZD6474 in glioblastoma. Br J Cancer. 2013 Jul 9;109(1):164-71. PMID: 23799852.

 

Samadi AK, Bazzill J, Zhang X, et al. Novel withanolides target medullary thyroid cancer through inhibition of both RET phosphorylation and the mammalian target of rapamycin pathway. Surgery. 2012 Dec;152(6):1238-47. PMID: 23158190.

 

Vitagliano D, De Falco V, Tamburrino A, et al. The tyrosine kinase inhibitor ZD6474 blocks proliferation of RET mutant medullary thyroid carcinoma cells. Endocr Relat Cancer. 2010 Nov 30;18(1):1-11. PMID: 20943719.

 

Yano S, Muguruma H, Matsumori Y, et al. Antitumor vascular strategy for controlling experimental metastatic spread of human small-cell lung cancer cells with ZD6474 in natural killer cell-depleted severe combined immunodeficient mice. Clin Cancer Res. 2005 Dec 15;11(24 Pt 1):8789-98. PMID: 16361567.

" Not dangerous goods.

LKT C1629 Cefoperazone Acid 1 g 88.3 β-lactam cephalosporin; penicillin binding protein inhibitor, mammalian mRNA splicing inhibitor. (6R,7R)-7-[[(2R)-[[(4-Ethyl-2,3-dioxo-1-piperazinyl)- carbonyl]amino](4-hydroxyphenyl)acetyl]amino]-3- [[(1-methyl-1H-tetrazol-5-yl)thio]methyl]-8-oxo-5- thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid 62893-19-0 ≥98% 645.47 C25H27N9O8S2 CCN1CCN(C(=O)C1=O)C(=O)NC(C2=CC=C(C=C2)O)C(=O)NC3C4N(C3=O)C(=C(CS4)CSC5=NN=NN5C)C(=O)O Unstable in alkaline solution. Slightly unstable in acid. Ambient 4°C "Aukema KG, Chohan KK, Plourde GL, et al. Small molecule inhibitors of yeast pre-mRNA splicing. ACS Chem Biol. 2009 Sep 18;4(9):759-68. PMID: 19634919.

 

Mohanty S, Singhal R, Sood S, et al. Comparative in vitro activity of beta-lactam/beta-lactamase inhibitor combinations against gram negative bacteria. Indian J Med Res. 2005 Nov;122(5):425-8. PMID: 16456257.

 

Yotsuji A, Mitsuyama J, Hori R, et al. Mechanism of action of cephalosporins and resistance caused by decreased affinity for penicillin-binding proteins in Bacteroides fragilis. Antimicrob Agents Chemother. 1988 Dec;32(12):1848-53. PMID: 3266730.

" Not dangerous goods.

LKT C1629 Cefoperazone Acid 5 g 271.7 β-lactam cephalosporin; penicillin binding protein inhibitor, mammalian mRNA splicing inhibitor. (6R,7R)-7-[[(2R)-[[(4-Ethyl-2,3-dioxo-1-piperazinyl)- carbonyl]amino](4-hydroxyphenyl)acetyl]amino]-3- [[(1-methyl-1H-tetrazol-5-yl)thio]methyl]-8-oxo-5- thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid 62893-19-0 ≥98% 645.47 C25H27N9O8S2 CCN1CCN(C(=O)C1=O)C(=O)NC(C2=CC=C(C=C2)O)C(=O)NC3C4N(C3=O)C(=C(CS4)CSC5=NN=NN5C)C(=O)O Unstable in alkaline solution. Slightly unstable in acid. Ambient 4°C "Aukema KG, Chohan KK, Plourde GL, et al. Small molecule inhibitors of yeast pre-mRNA splicing. ACS Chem Biol. 2009 Sep 18;4(9):759-68. PMID: 19634919.

 

Mohanty S, Singhal R, Sood S, et al. Comparative in vitro activity of beta-lactam/beta-lactamase inhibitor combinations against gram negative bacteria. Indian J Med Res. 2005 Nov;122(5):425-8. PMID: 16456257.

 

Yotsuji A, Mitsuyama J, Hori R, et al. Mechanism of action of cephalosporins and resistance caused by decreased affinity for penicillin-binding proteins in Bacteroides fragilis. Antimicrob Agents Chemother. 1988 Dec;32(12):1848-53. PMID: 3266730.

" Not dangerous goods.

LKT V0352 Vandetanib 25 mg 418.6 RET, EGFR, VEGFR2 inhibitor. ZD6474 443913-73-3 ≥98% 475.35 C22H24BrFN4O2 CN1CCC(CC1)COC2=C(C=C3C(=C2)N=CN=C3NC4=C(C=C(C=C4)Br)F)OC Ambient Ambient "Liu Y, Liu Y, Fan ZW, et al. Meta-analysis of the risks of hypertension and QTc prolongation in patients with advanced non-small cell lung cancer who were receiving vandetanib. Eur J Clin Pharmacol. 2015 May;71(5):541-7. PMID: 25753291

 

Shen J, Zheng H, Ruan J, et al. Autophagy inhibition induces enhanced proapoptotic effects of ZD6474 in glioblastoma. Br J Cancer. 2013 Jul 9;109(1):164-71. PMID: 23799852.

 

Samadi AK, Bazzill J, Zhang X, et al. Novel withanolides target medullary thyroid cancer through inhibition of both RET phosphorylation and the mammalian target of rapamycin pathway. Surgery. 2012 Dec;152(6):1238-47. PMID: 23158190.

 

Vitagliano D, De Falco V, Tamburrino A, et al. The tyrosine kinase inhibitor ZD6474 blocks proliferation of RET mutant medullary thyroid carcinoma cells. Endocr Relat Cancer. 2010 Nov 30;18(1):1-11. PMID: 20943719.

 

Yano S, Muguruma H, Matsumori Y, et al. Antitumor vascular strategy for controlling experimental metastatic spread of human small-cell lung cancer cells with ZD6474 in natural killer cell-depleted severe combined immunodeficient mice. Clin Cancer Res. 2005 Dec 15;11(24 Pt 1):8789-98. PMID: 16361567.

" Not dangerous goods.

LKT V0352 Vandetanib 100 mg 837.2 RET, EGFR, VEGFR2 inhibitor. ZD6474 443913-73-3 ≥98% 475.35 C22H24BrFN4O2 CN1CCC(CC1)COC2=C(C=C3C(=C2)N=CN=C3NC4=C(C=C(C=C4)Br)F)OC Ambient Ambient "Liu Y, Liu Y, Fan ZW, et al. Meta-analysis of the risks of hypertension and QTc prolongation in patients with advanced non-small cell lung cancer who were receiving vandetanib. Eur J Clin Pharmacol. 2015 May;71(5):541-7. PMID: 25753291

 

Shen J, Zheng H, Ruan J, et al. Autophagy inhibition induces enhanced proapoptotic effects of ZD6474 in glioblastoma. Br J Cancer. 2013 Jul 9;109(1):164-71. PMID: 23799852.

 

Samadi AK, Bazzill J, Zhang X, et al. Novel withanolides target medullary thyroid cancer through inhibition of both RET phosphorylation and the mammalian target of rapamycin pathway. Surgery. 2012 Dec;152(6):1238-47. PMID: 23158190.

 

Vitagliano D, De Falco V, Tamburrino A, et al. The tyrosine kinase inhibitor ZD6474 blocks proliferation of RET mutant medullary thyroid carcinoma cells. Endocr Relat Cancer. 2010 Nov 30;18(1):1-11. PMID: 20943719.

 

Yano S, Muguruma H, Matsumori Y, et al. Antitumor vascular strategy for controlling experimental metastatic spread of human small-cell lung cancer cells with ZD6474 in natural killer cell-depleted severe combined immunodeficient mice. Clin Cancer Res. 2005 Dec 15;11(24 Pt 1):8789-98. PMID: 16361567.

" Not dangerous goods.

LKT C1632 Cefotaxime Acid 500 mg 101.9 β-lactam cephalosporin; penicillin binding protein inhibitor. (6R,7R)-3-[(Acetyloxy)methyl]-7-[[(2Z)-(2-amino-4- thiazolyl)(methoxyimino)-acetyl]amino]-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid Cefotaxime; 7-[2-(2-amino-4-thiazolyl)-2-methoxyimino- acetamido]-cephalosporanic acid 63527-52-6 ≥91% 455.47 C16H17N5O7S2 CC(=O)OCC1=C(N2C(C(C2=O)NC(=O)C(=NOC)C3=CSC(=N3)N)SC1)C(=O)O Ambient 4°C Soluble in water. "Philpott-Howard J, Williams JD. Activity of cephalosporin antibiotics against Haemophilus influenzae. Scand J Infect Dis Suppl. 1983;39:109-11. PMID: 6606223.

 

LeFrock JL, Prince RA, Leff RD. Mechanism of action, antimicrobial activity, pharmacology, adverse effects, and clinical efficacy of cefotaxime. Pharmacotherapy. 1982 Jul-Aug;2(4):174-84. PMID: 6302641.

" Not dangerous goods.

LKT C1632 Cefotaxime Acid 1 g 169.9 β-lactam cephalosporin; penicillin binding protein inhibitor. (6R,7R)-3-[(Acetyloxy)methyl]-7-[[(2Z)-(2-amino-4- thiazolyl)(methoxyimino)-acetyl]amino]-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid Cefotaxime; 7-[2-(2-amino-4-thiazolyl)-2-methoxyimino- acetamido]-cephalosporanic acid 63527-52-6 ≥91% 455.47 C16H17N5O7S2 CC(=O)OCC1=C(N2C(C(C2=O)NC(=O)C(=NOC)C3=CSC(=N3)N)SC1)C(=O)O Ambient 4°C Soluble in water. "Philpott-Howard J, Williams JD. Activity of cephalosporin antibiotics against Haemophilus influenzae. Scand J Infect Dis Suppl. 1983;39:109-11. PMID: 6606223.

 

LeFrock JL, Prince RA, Leff RD. Mechanism of action, antimicrobial activity, pharmacology, adverse effects, and clinical efficacy of cefotaxime. Pharmacotherapy. 1982 Jul-Aug;2(4):174-84. PMID: 6302641.

" Not dangerous goods.

LKT C1632 Cefotaxime Acid 5 g 543.6 β-lactam cephalosporin; penicillin binding protein inhibitor. (6R,7R)-3-[(Acetyloxy)methyl]-7-[[(2Z)-(2-amino-4- thiazolyl)(methoxyimino)-acetyl]amino]-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid Cefotaxime; 7-[2-(2-amino-4-thiazolyl)-2-methoxyimino- acetamido]-cephalosporanic acid 63527-52-6 ≥91% 455.47 C16H17N5O7S2 CC(=O)OCC1=C(N2C(C(C2=O)NC(=O)C(=NOC)C3=CSC(=N3)N)SC1)C(=O)O Ambient 4°C Soluble in water. "Philpott-Howard J, Williams JD. Activity of cephalosporin antibiotics against Haemophilus influenzae. Scand J Infect Dis Suppl. 1983;39:109-11. PMID: 6606223.

 

LeFrock JL, Prince RA, Leff RD. Mechanism of action, antimicrobial activity, pharmacology, adverse effects, and clinical efficacy of cefotaxime. Pharmacotherapy. 1982 Jul-Aug;2(4):174-84. PMID: 6302641.

" Not dangerous goods.

LKT C1633 Cefotaxime Sodium 500 mg 74.8 β-lactam cephalosporin; penicillin binding protein inhibitor. (6R,7R)-3-[(Acetyloxy)methyl]-7-[[(2Z)-(2-amino-4- thiazolyl)(methoxyimino)-acetyl]amino]-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid sodium salt Cefotaxim sodium salt; Cefotax; Claforan; Pretor; Tolycar 64485-93-4 ≥96% 477.45 C16H16N5NaO7S2 CC(=O)OCC1=C(N2C(C(C2=O)NC(=O)C(=NOC)C3=CSC(=N3)N)SC1)C(=O)[O-].[Na+] Hygroscopic. Ambient 4°C Soluble in water. "Philpott-Howard J, Williams JD. Activity of cephalosporin antibiotics against Haemophilus influenzae. Scand J Infect Dis Suppl. 1983;39:109-11. PMID: 6606223.

 

LeFrock JL, Prince RA, Leff RD. Mechanism of action, antimicrobial activity, pharmacology, adverse effects, and clinical efficacy of cefotaxime. Pharmacotherapy. 1982 Jul-Aug;2(4):174-84. PMID: 6302641.

" Not dangerous goods.

LKT C1633 Cefotaxime Sodium 1 g 122.3 β-lactam cephalosporin; penicillin binding protein inhibitor. (6R,7R)-3-[(Acetyloxy)methyl]-7-[[(2Z)-(2-amino-4- thiazolyl)(methoxyimino)-acetyl]amino]-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid sodium salt Cefotaxim sodium salt; Cefotax; Claforan; Pretor; Tolycar 64485-93-4 ≥96% 477.45 C16H16N5NaO7S2 CC(=O)OCC1=C(N2C(C(C2=O)NC(=O)C(=NOC)C3=CSC(=N3)N)SC1)C(=O)[O-].[Na+] Hygroscopic. Ambient 4°C Soluble in water. "Philpott-Howard J, Williams JD. Activity of cephalosporin antibiotics against Haemophilus influenzae. Scand J Infect Dis Suppl. 1983;39:109-11. PMID: 6606223.

 

LeFrock JL, Prince RA, Leff RD. Mechanism of action, antimicrobial activity, pharmacology, adverse effects, and clinical efficacy of cefotaxime. Pharmacotherapy. 1982 Jul-Aug;2(4):174-84. PMID: 6302641.

" Not dangerous goods.

LKT C1633 Cefotaxime Sodium 5 g 434.9 β-lactam cephalosporin; penicillin binding protein inhibitor. (6R,7R)-3-[(Acetyloxy)methyl]-7-[[(2Z)-(2-amino-4- thiazolyl)(methoxyimino)-acetyl]amino]-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid sodium salt Cefotaxim sodium salt; Cefotax; Claforan; Pretor; Tolycar 64485-93-4 ≥96% 477.45 C16H16N5NaO7S2 CC(=O)OCC1=C(N2C(C(C2=O)NC(=O)C(=NOC)C3=CSC(=N3)N)SC1)C(=O)[O-].[Na+] Hygroscopic. Ambient 4°C Soluble in water. "Philpott-Howard J, Williams JD. Activity of cephalosporin antibiotics against Haemophilus influenzae. Scand J Infect Dis Suppl. 1983;39:109-11. PMID: 6606223.

 

LeFrock JL, Prince RA, Leff RD. Mechanism of action, antimicrobial activity, pharmacology, adverse effects, and clinical efficacy of cefotaxime. Pharmacotherapy. 1982 Jul-Aug;2(4):174-84. PMID: 6302641.

" Not dangerous goods.

LKT V0275 [Arg8]-Vasotocin 1 mg 60 Peptide, oxytocin-vasopressin analog. ≥95% 1050.23 C43H67N15O12S2 CCC(C)C1C(=O)NC(C(=O)NC(C(=O)NC(CSSCC(C(=O)NC(C(=O)N1)CC2=CC=C(C=C2)O)N)C(=O)N3CCCC3C(=O)NC(CCCN=C(N)N)C(=O)NCC(=O)N)CC(=O)N)CCC(=O)N Ambient -20°C "Gesto M, Soengas JL, Rodríguez-Illamola A, et al. Arginine vasotocin treatment induces a stress response and exerts a potent anorexigenic effect in rainbow trout, Oncorhynchus mykiss. J Neuroendocrinol. 2013 Dec 16. [Epub ahead of print]. PMID: 24341528.

 

Kim JK, Kim IH, Heo JH, et al. Arginine vasotocin (AVT) triggers courtship behavior without exposure to external stimuli and modulates the olfactory response of male Hynobius leechii salamanders. Zoolog Sci. 2013 Nov;30(11):929-37. PMID: 24199858.

 

Hasunuma I, Toyoda F, Okada R, et al. Roles of arginine vasotocin receptors in the brain and pituitary of submammalian vertebrates. Int Rev Cell Mol Biol. 2013;304:191-225. PMID: 23809437.

" Not dangerous goods.

LKT V0275 [Arg8]-Vasotocin 2 mg 101.9 Peptide, oxytocin-vasopressin analog. ≥95% 1050.23 C43H67N15O12S2 CCC(C)C1C(=O)NC(C(=O)NC(C(=O)NC(CSSCC(C(=O)NC(C(=O)N1)CC2=CC=C(C=C2)O)N)C(=O)N3CCCC3C(=O)NC(CCCN=C(N)N)C(=O)NCC(=O)N)CC(=O)N)CCC(=O)N Ambient -20°C "Gesto M, Soengas JL, Rodríguez-Illamola A, et al. Arginine vasotocin treatment induces a stress response and exerts a potent anorexigenic effect in rainbow trout, Oncorhynchus mykiss. J Neuroendocrinol. 2013 Dec 16. [Epub ahead of print]. PMID: 24341528.

 

Kim JK, Kim IH, Heo JH, et al. Arginine vasotocin (AVT) triggers courtship behavior without exposure to external stimuli and modulates the olfactory response of male Hynobius leechii salamanders. Zoolog Sci. 2013 Nov;30(11):929-37. PMID: 24199858.

 

Hasunuma I, Toyoda F, Okada R, et al. Roles of arginine vasotocin receptors in the brain and pituitary of submammalian vertebrates. Int Rev Cell Mol Biol. 2013;304:191-225. PMID: 23809437.

" Not dangerous goods.

LKT V0275 [Arg8]-Vasotocin 5 mg 180 Peptide, oxytocin-vasopressin analog. ≥95% 1050.23 C43H67N15O12S2 CCC(C)C1C(=O)NC(C(=O)NC(C(=O)NC(CSSCC(C(=O)NC(C(=O)N1)CC2=CC=C(C=C2)O)N)C(=O)N3CCCC3C(=O)NC(CCCN=C(N)N)C(=O)NCC(=O)N)CC(=O)N)CCC(=O)N Ambient -20°C "Gesto M, Soengas JL, Rodríguez-Illamola A, et al. Arginine vasotocin treatment induces a stress response and exerts a potent anorexigenic effect in rainbow trout, Oncorhynchus mykiss. J Neuroendocrinol. 2013 Dec 16. [Epub ahead of print]. PMID: 24341528.

 

Kim JK, Kim IH, Heo JH, et al. Arginine vasotocin (AVT) triggers courtship behavior without exposure to external stimuli and modulates the olfactory response of male Hynobius leechii salamanders. Zoolog Sci. 2013 Nov;30(11):929-37. PMID: 24199858.

 

Hasunuma I, Toyoda F, Okada R, et al. Roles of arginine vasotocin receptors in the brain and pituitary of submammalian vertebrates. Int Rev Cell Mol Biol. 2013;304:191-225. PMID: 23809437.

" Not dangerous goods.

LKT C1635 Ceftazidime Hydrate 1 g 120.1 β-lactam cephalosporin; penicillin binding protein inhibitor. 1-[[(6R,7R)-7-[[(2Z)-(2-amino-4-thiazolyl)- [(1-carboxy-1-methylethoxy)imino]acetyl]amino]-2-carboxy-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-en-3-yl]methyl]pyridinum inner salt GR-20263; Fortum;  (C22H22N6O7S2 · xH2O) 78439-06-2 ≥97% 546.58 C22H22N6O7S2 xH2O CC(C)(C(=O)O)ON=C(C1=CSC(=N1)N)C(=O)NC2C3N(C2=O)C(=C(CS3)C[N+]4=CC=CC=C4)C(=O)[O-] Ambient 4°C Slightly soluble in water. "Chantratita N, Rholl DA, Sim B, et al. Antimicrobial resistance to ceftazidime involving loss of penicillin-binding protein 3 in Burkholderia pseudomallei. Proc Natl Acad Sci U S A. 2011 Oct 11;108(41):17165-70. PMID: 21969582.

 

Phelps DJ, Carlton DD, Farrell CA, et al. Affinity of cephalosporins for beta-lactamases as a factor in antibacterial efficacy. Antimicrob Agents Chemother. 1986 May;29(5):845-8. PMID: 3524432.

" Not dangerous goods.

LKT C1635 Ceftazidime Hydrate 5 g 485.4 β-lactam cephalosporin; penicillin binding protein inhibitor. 1-[[(6R,7R)-7-[[(2Z)-(2-amino-4-thiazolyl)- [(1-carboxy-1-methylethoxy)imino]acetyl]amino]-2-carboxy-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-en-3-yl]methyl]pyridinum inner salt GR-20263; Fortum;  (C22H22N6O7S2 · xH2O) 78439-06-2 ≥97% 546.58 C22H22N6O7S2 xH2O CC(C)(C(=O)O)ON=C(C1=CSC(=N1)N)C(=O)NC2C3N(C2=O)C(=C(CS3)C[N+]4=CC=CC=C4)C(=O)[O-] Ambient 4°C Slightly soluble in water. "Chantratita N, Rholl DA, Sim B, et al. Antimicrobial resistance to ceftazidime involving loss of penicillin-binding protein 3 in Burkholderia pseudomallei. Proc Natl Acad Sci U S A. 2011 Oct 11;108(41):17165-70. PMID: 21969582.

 

Phelps DJ, Carlton DD, Farrell CA, et al. Affinity of cephalosporins for beta-lactamases as a factor in antibacterial efficacy. Antimicrob Agents Chemother. 1986 May;29(5):845-8. PMID: 3524432.

" Not dangerous goods.

LKT V0274 [Lys8]-Vasopressin 1 mg 60 Peptide, vasopressin analog; V1/2 agonist. ≥95% 1056.24 C46H65N13O12S2 C1CC(N(C1)C(=O)C2CSSCC(C(=O)NC(C(=O)NC(C(=O)NC(C(=O)NC(C(=O)N2)CC(=O)N)CCC(=O)N)CC3=CC=CC=C3)CC4=CC=C(C=C4)O)N)C(=O)NC(CCCN=C(N)N)C(=O)NCC(=O)N Ambient -20°C "Chelko SP, Schmiedt CW, Lewis TH, et al. Vasopressin-induced constriction of the isolated rat occipital artery is segment dependent. J Vasc Res. 2013;50(6):478-85. PMID: 24192548.

 

Mastropaolo M, Zizzo MG, Auteri M, et al. Arginine vasopressin, via activation of post-junctional V1 receptors, induces contractile effects in mouse distal colon. Regul Pept. 2013 Nov 10;187:29-34. PMID: 24185041.

 

Salazar M, Hu BB, Vazquez J, et al. Exogenous Vasopressin-Induced Hyponatremia in Patients With Vasodilatory Shock: Two Case Reports and Literature Review. J Intensive Care Med. 2013 Oct 7. [Epub ahead of print]. PMID: 24106070.

" Not dangerous goods.

LKT V0274 [Lys8]-Vasopressin 2 mg 101.9 Peptide, vasopressin analog; V1/2 agonist. ≥95% 1056.24 C46H65N13O12S2 C1CC(N(C1)C(=O)C2CSSCC(C(=O)NC(C(=O)NC(C(=O)NC(C(=O)NC(C(=O)N2)CC(=O)N)CCC(=O)N)CC3=CC=CC=C3)CC4=CC=C(C=C4)O)N)C(=O)NC(CCCN=C(N)N)C(=O)NCC(=O)N Ambient -20°C "Chelko SP, Schmiedt CW, Lewis TH, et al. Vasopressin-induced constriction of the isolated rat occipital artery is segment dependent. J Vasc Res. 2013;50(6):478-85. PMID: 24192548.

 

Mastropaolo M, Zizzo MG, Auteri M, et al. Arginine vasopressin, via activation of post-junctional V1 receptors, induces contractile effects in mouse distal colon. Regul Pept. 2013 Nov 10;187:29-34. PMID: 24185041.

 

Salazar M, Hu BB, Vazquez J, et al. Exogenous Vasopressin-Induced Hyponatremia in Patients With Vasodilatory Shock: Two Case Reports and Literature Review. J Intensive Care Med. 2013 Oct 7. [Epub ahead of print]. PMID: 24106070.

" Not dangerous goods.

LKT V0274 [Lys8]-Vasopressin 5 mg 180 Peptide, vasopressin analog; V1/2 agonist. ≥95% 1056.24 C46H65N13O12S2 C1CC(N(C1)C(=O)C2CSSCC(C(=O)NC(C(=O)NC(C(=O)NC(C(=O)NC(C(=O)N2)CC(=O)N)CCC(=O)N)CC3=CC=CC=C3)CC4=CC=C(C=C4)O)N)C(=O)NC(CCCN=C(N)N)C(=O)NCC(=O)N Ambient -20°C "Chelko SP, Schmiedt CW, Lewis TH, et al. Vasopressin-induced constriction of the isolated rat occipital artery is segment dependent. J Vasc Res. 2013;50(6):478-85. PMID: 24192548.

 

Mastropaolo M, Zizzo MG, Auteri M, et al. Arginine vasopressin, via activation of post-junctional V1 receptors, induces contractile effects in mouse distal colon. Regul Pept. 2013 Nov 10;187:29-34. PMID: 24185041.

 

Salazar M, Hu BB, Vazquez J, et al. Exogenous Vasopressin-Induced Hyponatremia in Patients With Vasodilatory Shock: Two Case Reports and Literature Review. J Intensive Care Med. 2013 Oct 7. [Epub ahead of print]. PMID: 24106070.

" Not dangerous goods.

LKT C1637 Ceftriaxone Sodium 250 mg 67.9 β-lactam cephalosporin; penicillin binding protein inhibitor. (6R,7R)-7-[[(2Z)-(2-Amino-4-thiazolyl)(methoxyimino)acetyl]amino]-8-oxo-3-[[(1,2,5,6-tetrahydro-2-methyl-5,6-dioxo-1,2,4-triazin-3-yl)-thio]methyl]-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid Disodium Salt Hemiheptahydrate Ceftriaxone disodium slat hemiheptahydrate; Rocefin; Rocephine 104376-79-6 ≥98% 598.54 C18H16N8O7S3Na2  7/2H2O CN1C(=NC(=O)C(=N1)[O-])SCC2=C(N3C(C(C3=O)NC(=O)C(=NOC)C4=CSC(=N4)N)SC2)C(=O)[O-].O.[Na+].[Na+] Ambient 4°C Soluble in water (40 g/100 ml). DMSO 1 mg/mL. "Cui C, Cui Y, Gao J, et al. Neuroprotective effect of ceftriaxone in a rat model of traumatic brain injury. Neurol Sci. 2014 May;35(5):695-700. PMID: 24277205.

 

Sari Y, Prieto AL, Barton SJ, et al. Ceftriaxone-induced up-regulation of cortical and striatal GLT1 in the R6/2 model of Huntington's disease. J Biomed Sci. 2010 Jul 27;17:62. PMID: 20663216.

 

Rawls SM, Cavallo F, Capasso A, et al. The beta-lactam antibiotic ceftriaxone inhibits physical dependence and abstinence-induced withdrawal from cocaine, amphetamine, methamphetamine, and clorazepate in planarians. Eur J Pharmacol. 2008 Apr 28;584(2-3):278-84. PMID: 18342307.

 

Barriere SL, Flaherty JF. Third-generation cephalosporins: a critical evaluation. Clin Pharm. 1984 Jul-Aug;3(4):351-73. PMID: 6432420.

" Xi, Xn Not dangerous goods.

LKT C1637 Ceftriaxone Sodium 500 mg 115.5 β-lactam cephalosporin; penicillin binding protein inhibitor. (6R,7R)-7-[[(2Z)-(2-Amino-4-thiazolyl)(methoxyimino)acetyl]amino]-8-oxo-3-[[(1,2,5,6-tetrahydro-2-methyl-5,6-dioxo-1,2,4-triazin-3-yl)-thio]methyl]-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid Disodium Salt Hemiheptahydrate Ceftriaxone disodium slat hemiheptahydrate; Rocefin; Rocephine 104376-79-6 ≥98% 598.54 C18H16N8O7S3Na2  7/2H2O CN1C(=NC(=O)C(=N1)[O-])SCC2=C(N3C(C(C3=O)NC(=O)C(=NOC)C4=CSC(=N4)N)SC2)C(=O)[O-].O.[Na+].[Na+] Ambient 4°C Soluble in water (40 g/100 ml). DMSO 1 mg/mL. "Cui C, Cui Y, Gao J, et al. Neuroprotective effect of ceftriaxone in a rat model of traumatic brain injury. Neurol Sci. 2014 May;35(5):695-700. PMID: 24277205.

 

Sari Y, Prieto AL, Barton SJ, et al. Ceftriaxone-induced up-regulation of cortical and striatal GLT1 in the R6/2 model of Huntington's disease. J Biomed Sci. 2010 Jul 27;17:62. PMID: 20663216.

 

Rawls SM, Cavallo F, Capasso A, et al. The beta-lactam antibiotic ceftriaxone inhibits physical dependence and abstinence-induced withdrawal from cocaine, amphetamine, methamphetamine, and clorazepate in planarians. Eur J Pharmacol. 2008 Apr 28;584(2-3):278-84. PMID: 18342307.

 

Barriere SL, Flaherty JF. Third-generation cephalosporins: a critical evaluation. Clin Pharm. 1984 Jul-Aug;3(4):351-73. PMID: 6432420.

" Xi, Xn Not dangerous goods.

LKT C1637 Ceftriaxone Sodium 1 g 190.3 β-lactam cephalosporin; penicillin binding protein inhibitor. (6R,7R)-7-[[(2Z)-(2-Amino-4-thiazolyl)(methoxyimino)acetyl]amino]-8-oxo-3-[[(1,2,5,6-tetrahydro-2-methyl-5,6-dioxo-1,2,4-triazin-3-yl)-thio]methyl]-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid Disodium Salt Hemiheptahydrate Ceftriaxone disodium slat hemiheptahydrate; Rocefin; Rocephine 104376-79-6 ≥98% 598.54 C18H16N8O7S3Na2  7/2H2O CN1C(=NC(=O)C(=N1)[O-])SCC2=C(N3C(C(C3=O)NC(=O)C(=NOC)C4=CSC(=N4)N)SC2)C(=O)[O-].O.[Na+].[Na+] Ambient 4°C Soluble in water (40 g/100 ml). DMSO 1 mg/mL. "Cui C, Cui Y, Gao J, et al. Neuroprotective effect of ceftriaxone in a rat model of traumatic brain injury. Neurol Sci. 2014 May;35(5):695-700. PMID: 24277205.

 

Sari Y, Prieto AL, Barton SJ, et al. Ceftriaxone-induced up-regulation of cortical and striatal GLT1 in the R6/2 model of Huntington's disease. J Biomed Sci. 2010 Jul 27;17:62. PMID: 20663216.

 

Rawls SM, Cavallo F, Capasso A, et al. The beta-lactam antibiotic ceftriaxone inhibits physical dependence and abstinence-induced withdrawal from cocaine, amphetamine, methamphetamine, and clorazepate in planarians. Eur J Pharmacol. 2008 Apr 28;584(2-3):278-84. PMID: 18342307.

 

Barriere SL, Flaherty JF. Third-generation cephalosporins: a critical evaluation. Clin Pharm. 1984 Jul-Aug;3(4):351-73. PMID: 6432420.

" Xi, Xn Not dangerous goods.

LKT V0273 Vasoactive Intestinal Peptide 0.5 mg 156 Endogenous peptide hormone, involved in enteric movement and hormone secretion; VPAC1/2 agonist. 40077-57-4 ≥95% 3325.7 C57H70N12O9S1 CCC(C)C(C(=O)NC(CC(C)C)C(=O)NC(CC(=O)N)C(=O)O)NC(=O)C(CO)NC(=O)C(CC(=O)N)NC(=O)C(CC(C)C)NC(=O)C(CC1=CC=C(C=C1)O)NC(=O)C(CCCCN)NC(=O)C(CCCCN)NC(=O)C(C(C)C)NC(=O)C(C)NC(=O)C(CCSC)NC(=O)C(CCC(=O)N)NC(=O)C(CCCCN)NC(=O)C(CCCNC(=N)N)NC(=O)C(CC(C)C)NC(=O)C(CCCNC(=N)N)NC(=O)C(C(C)O)NC(=O)C(CC2=CC=C(C=C2)O)NC(=O)C(CC(=O)N)NC(=O)C(CC(=O)O)NC(=O)C(C(C)O)NC(=O)C(CC3=CC=CC=C3)NC(=O)C(C(C)C)NC(=O)C(C)NC(=O)C(CC(=O)O)NC(=O)C(CO)NC(=O)C(CC4=CN=CN4)N Ambient -20°C "Hauk V, Azzam S, Calo G, et al. Vasoactive intestinal Peptide induces an immunosuppressant microenvironment in the maternal-fetal interface of non-obese diabetic mice and improves early pregnancy outcome. Am J Reprod Immunol. 2014 Feb;71(2):120-30. PMID: 24405265.

 

Fraccaroli L, Grasso E, Hauk V, et al. Contribution of Vasoactive Intestinal Peptide to Immune Homeostasis in Trophoblast-Maternal Leukocyte Interaction under LPS Stimulation. Neuroimmunomodulation. 2014;21(1):21-30. PMID: 24135863.

 

Mathioudakis A, Chatzimavridou-Grigoriadou V, Evangelopoulou E, et al. Vasoactive intestinal Peptide inhaled agonists: potential role in respiratory therapeutics. Hippokratia. 2013 Jan;17(1):12-6. PMID: 23935337.

" Not dangerous goods.

LKT V0273 Vasoactive Intestinal Peptide 1 mg 264.1 Endogenous peptide hormone, involved in enteric movement and hormone secretion; VPAC1/2 agonist. 40077-57-4 ≥95% 3325.7 C57H70N12O9S1 CCC(C)C(C(=O)NC(CC(C)C)C(=O)NC(CC(=O)N)C(=O)O)NC(=O)C(CO)NC(=O)C(CC(=O)N)NC(=O)C(CC(C)C)NC(=O)C(CC1=CC=C(C=C1)O)NC(=O)C(CCCCN)NC(=O)C(CCCCN)NC(=O)C(C(C)C)NC(=O)C(C)NC(=O)C(CCSC)NC(=O)C(CCC(=O)N)NC(=O)C(CCCCN)NC(=O)C(CCCNC(=N)N)NC(=O)C(CC(C)C)NC(=O)C(CCCNC(=N)N)NC(=O)C(C(C)O)NC(=O)C(CC2=CC=C(C=C2)O)NC(=O)C(CC(=O)N)NC(=O)C(CC(=O)O)NC(=O)C(C(C)O)NC(=O)C(CC3=CC=CC=C3)NC(=O)C(C(C)C)NC(=O)C(C)NC(=O)C(CC(=O)O)NC(=O)C(CO)NC(=O)C(CC4=CN=CN4)N Ambient -20°C "Hauk V, Azzam S, Calo G, et al. Vasoactive intestinal Peptide induces an immunosuppressant microenvironment in the maternal-fetal interface of non-obese diabetic mice and improves early pregnancy outcome. Am J Reprod Immunol. 2014 Feb;71(2):120-30. PMID: 24405265.

 

Fraccaroli L, Grasso E, Hauk V, et al. Contribution of Vasoactive Intestinal Peptide to Immune Homeostasis in Trophoblast-Maternal Leukocyte Interaction under LPS Stimulation. Neuroimmunomodulation. 2014;21(1):21-30. PMID: 24135863.

 

Mathioudakis A, Chatzimavridou-Grigoriadou V, Evangelopoulou E, et al. Vasoactive intestinal Peptide inhaled agonists: potential role in respiratory therapeutics. Hippokratia. 2013 Jan;17(1):12-6. PMID: 23935337.

" Not dangerous goods.

LKT V0273 Vasoactive Intestinal Peptide 2.5 mg 468.2 Endogenous peptide hormone, involved in enteric movement and hormone secretion; VPAC1/2 agonist. 40077-57-4 ≥95% 3325.7 C57H70N12O9S1 CCC(C)C(C(=O)NC(CC(C)C)C(=O)NC(CC(=O)N)C(=O)O)NC(=O)C(CO)NC(=O)C(CC(=O)N)NC(=O)C(CC(C)C)NC(=O)C(CC1=CC=C(C=C1)O)NC(=O)C(CCCCN)NC(=O)C(CCCCN)NC(=O)C(C(C)C)NC(=O)C(C)NC(=O)C(CCSC)NC(=O)C(CCC(=O)N)NC(=O)C(CCCCN)NC(=O)C(CCCNC(=N)N)NC(=O)C(CC(C)C)NC(=O)C(CCCNC(=N)N)NC(=O)C(C(C)O)NC(=O)C(CC2=CC=C(C=C2)O)NC(=O)C(CC(=O)N)NC(=O)C(CC(=O)O)NC(=O)C(C(C)O)NC(=O)C(CC3=CC=CC=C3)NC(=O)C(C(C)C)NC(=O)C(C)NC(=O)C(CC(=O)O)NC(=O)C(CO)NC(=O)C(CC4=CN=CN4)N Ambient -20°C "Hauk V, Azzam S, Calo G, et al. Vasoactive intestinal Peptide induces an immunosuppressant microenvironment in the maternal-fetal interface of non-obese diabetic mice and improves early pregnancy outcome. Am J Reprod Immunol. 2014 Feb;71(2):120-30. PMID: 24405265.

 

Fraccaroli L, Grasso E, Hauk V, et al. Contribution of Vasoactive Intestinal Peptide to Immune Homeostasis in Trophoblast-Maternal Leukocyte Interaction under LPS Stimulation. Neuroimmunomodulation. 2014;21(1):21-30. PMID: 24135863.

 

Mathioudakis A, Chatzimavridou-Grigoriadou V, Evangelopoulou E, et al. Vasoactive intestinal Peptide inhaled agonists: potential role in respiratory therapeutics. Hippokratia. 2013 Jan;17(1):12-6. PMID: 23935337.

" Not dangerous goods.

LKT C1644 Celecoxib 500 mg 165.1 NSAID; COX-2 inhibitor. 4-[5-(4-Methylphenyl)-3-(trifluoromethyl)-1H- pyrazol-1-yl]benzenesulfonamide SC-58635; Celebrex 169590-42-5 ≥98% 381.37 C17H14F3N3O2S CC1=CC=C(C=C1)C2=CC(=NN2C3=CC=C(C=C3)S(=O)(=O)N)C(F)(F)F Ambient Ambient Insoluble in water. Soluble in DMSO (200 mg/mL), ethanol (100 mg/mL). "Shao D, Kan M, Qiao P, et al. Celecoxib induces apoptosis via a mitochondria dependent pathway in the H22 mouse hepatoma cell line. Mol Med Rep. 2014 Oct;10(4):2093-8. PMID: 25109418.

 

Annamanedi M, Kalle AM. Celecoxib sensitizes Staphylococcus aureus to antibiotics in macrophages by modulating SIRT1. PLoS One. 2014 Jun 20;9(6):e99285. PMID: 24950067.

 

Li WW, Long GX, Liu DB, et al. Cyclooxygenase-2 inhibitor celecoxib suppresses invasion and migration of nasopharyngeal carcinoma cell lines through a decrease in matrix metalloproteinase-2 and -9 activity. Pharmazie. 2014 Feb;69(2):132-7. PMID: 24640603.

 

Shi S, Klotz U. Clinical use and pharmacological properties of selective COX-2 inhibitors. Eur J Clin Pharmacol. 2008 Mar;64(3):233-52. PMID: 17999057.

 

Subbaramaiah K, Howe LR, Bhardwaj P, et al. Obesity is associated with inflammation and elevated aromatase expression in the mouse mammary gland. Cancer Prev Res (Phila). 2011 Mar;4(3):329-346. PMID: 21372033." Not dangerous goods.

LKT C1644 Celecoxib 1 g 254.1 NSAID; COX-2 inhibitor. 4-[5-(4-Methylphenyl)-3-(trifluoromethyl)-1H- pyrazol-1-yl]benzenesulfonamide SC-58635; Celebrex 169590-42-5 ≥98% 381.37 C17H14F3N3O2S CC1=CC=C(C=C1)C2=CC(=NN2C3=CC=C(C=C3)S(=O)(=O)N)C(F)(F)F Ambient Ambient Insoluble in water. Soluble in DMSO (200 mg/mL), ethanol (100 mg/mL). "Shao D, Kan M, Qiao P, et al. Celecoxib induces apoptosis via a mitochondria dependent pathway in the H22 mouse hepatoma cell line. Mol Med Rep. 2014 Oct;10(4):2093-8. PMID: 25109418.

 

Annamanedi M, Kalle AM. Celecoxib sensitizes Staphylococcus aureus to antibiotics in macrophages by modulating SIRT1. PLoS One. 2014 Jun 20;9(6):e99285. PMID: 24950067.

 

Li WW, Long GX, Liu DB, et al. Cyclooxygenase-2 inhibitor celecoxib suppresses invasion and migration of nasopharyngeal carcinoma cell lines through a decrease in matrix metalloproteinase-2 and -9 activity. Pharmazie. 2014 Feb;69(2):132-7. PMID: 24640603.

 

Shi S, Klotz U. Clinical use and pharmacological properties of selective COX-2 inhibitors. Eur J Clin Pharmacol. 2008 Mar;64(3):233-52. PMID: 17999057.

 

Subbaramaiah K, Howe LR, Bhardwaj P, et al. Obesity is associated with inflammation and elevated aromatase expression in the mouse mammary gland. Cancer Prev Res (Phila). 2011 Mar;4(3):329-346. PMID: 21372033." Not dangerous goods.

LKT C1648 α-Cembrenediol 10 mg 236.6 Diterpene found in Anisomeles. (1S,2E,4S,6R,7E,11E)-2,7,11-Cembratriene-4,6-diol 57605-80-8 ≥98% 306.48 C20H34O2 CC1=CCCC(=CC(CC(C=CC(CC1)C(C)C)(C)O)O)C Ambient -80°C "Kulkarni RR, Shurpali K, Gawde RL, et al. Phyllocladane diterpenes from Anisomeles heyneana. J Asian Nat Prod Res. 2012;14(12):1162-8. PMID: 23157282.

 

Kennedy BS, Nielsen MT, Severson RF. Biorationals from Nicotiana protect cucumbers against Colletotrichum lagenarium (Pass.) ell. & halst disease development. J Chem Ecol. 1995 Feb;21(2):221-31. PMID: 24234021.

" Not dangerous goods.

LKT V0252 Vancomycin Hydrochloride 100 mg 40.7 Glycopeptide, binds D-Ala-D-Ala; cell wall synthesis inhibitor. 1050 IU/mg, bio assay "(S(suba))-(3S,6R,7R,22R,23S,26S,36R,38aR)-44-((2-O-(3-Amino-2,3,6-trideoxy-3-C-methyl-alpha-L-lyxo-hexopyranosyl)-beta-D-glucopyranosyl)oxy)-3-(carbamoylmethyl)-10,19-dichloro-2,3,4,5,6,7,23,24,25,26,36,37,38,38a-tetradecahydro-7,22,28,30,32-pentahydroxy-6-((2R)-4-methyl-2-(methylamino)valeramido)-2,5,24,38,39-pentaoxo-22H-8,11:18,21-dietheno-23,36-(iminomethano)-13,16:31,35-

" Vancomycine; Vancocin; Lyphocin; Vancor 1404-93-9 ≥1050 IU/mg, bio assay 1485.73 C66H75Cl2N9O24 HCl CC1C(C(CC(O1)OC2C(C(C(OC2OC3=C4C=C5C=C3OC6=C(C=C(C=C6)C(C(C(=O)NC(C(=O)NC5C(=O)NC7C8=CC(=C(C=C8)O)C9=C(C=C(C=C9C(NC(=O)C(C(C1=CC(=C(O4)C=C1)Cl)O)NC7=O)C(=O)O)O)O)CC(=O)N)NC(=O)C(CC(C)C)NC)O)Cl)CO)O)O)(C)N)O Hygroscopic Ambient Ambient Soluble in water. Moderately soluble in methanol.  Insoluble in acetone and ether. "Allen CA, Babakhani F, Sears P, et al. Both fidaxomicin and vancomycin inhibit outgrowth of Clostridium difficile spores. Antimicrob Agents Chemother. 2013 Jan;57(1):664-7. PMID: 23147724.

 

Chakraborty SP, Sahu SK, Pramanik P, et al. In vitro antimicrobial activity of nanoconjugated vancomycin against drug resistant Staphylococcus aureus. Int J Pharm. 2012 Oct 15;436(1-2):659-76. PMID: 22841851.

 

Nailor MD, Sobel JD. Antibiotics for gram-positive bacterial infection: vancomycin, teicoplanin, quinupristin/dalfopristin, oxazolidinones, daptomycin, telavancin, and ceftaroline. Med Clin North Am. 2011 Jul;95(4):723-42, vii. PMID: 21679789.

" Not dangerous goods.

LKT V0252 Vancomycin Hydrochloride 250 mg 65.3 Glycopeptide, binds D-Ala-D-Ala; cell wall synthesis inhibitor. 1050 IU/mg, bio assay "(S(suba))-(3S,6R,7R,22R,23S,26S,36R,38aR)-44-((2-O-(3-Amino-2,3,6-trideoxy-3-C-methyl-alpha-L-lyxo-hexopyranosyl)-beta-D-glucopyranosyl)oxy)-3-(carbamoylmethyl)-10,19-dichloro-2,3,4,5,6,7,23,24,25,26,36,37,38,38a-tetradecahydro-7,22,28,30,32-pentahydroxy-6-((2R)-4-methyl-2-(methylamino)valeramido)-2,5,24,38,39-pentaoxo-22H-8,11:18,21-dietheno-23,36-(iminomethano)-13,16:31,35-

" Vancomycine; Vancocin; Lyphocin; Vancor 1404-93-9 ≥1050 IU/mg, bio assay 1485.73 C66H75Cl2N9O24 HCl CC1C(C(CC(O1)OC2C(C(C(OC2OC3=C4C=C5C=C3OC6=C(C=C(C=C6)C(C(C(=O)NC(C(=O)NC5C(=O)NC7C8=CC(=C(C=C8)O)C9=C(C=C(C=C9C(NC(=O)C(C(C1=CC(=C(O4)C=C1)Cl)O)NC7=O)C(=O)O)O)O)CC(=O)N)NC(=O)C(CC(C)C)NC)O)Cl)CO)O)O)(C)N)O Hygroscopic Ambient Ambient Soluble in water. Moderately soluble in methanol.  Insoluble in acetone and ether. "Allen CA, Babakhani F, Sears P, et al. Both fidaxomicin and vancomycin inhibit outgrowth of Clostridium difficile spores. Antimicrob Agents Chemother. 2013 Jan;57(1):664-7. PMID: 23147724.

 

Chakraborty SP, Sahu SK, Pramanik P, et al. In vitro antimicrobial activity of nanoconjugated vancomycin against drug resistant Staphylococcus aureus. Int J Pharm. 2012 Oct 15;436(1-2):659-76. PMID: 22841851.

 

Nailor MD, Sobel JD. Antibiotics for gram-positive bacterial infection: vancomycin, teicoplanin, quinupristin/dalfopristin, oxazolidinones, daptomycin, telavancin, and ceftaroline. Med Clin North Am. 2011 Jul;95(4):723-42, vii. PMID: 21679789.

" Not dangerous goods.

LKT V0252 Vancomycin Hydrochloride 1 g 183.4 Glycopeptide, binds D-Ala-D-Ala; cell wall synthesis inhibitor. 1050 IU/mg, bio assay "(S(suba))-(3S,6R,7R,22R,23S,26S,36R,38aR)-44-((2-O-(3-Amino-2,3,6-trideoxy-3-C-methyl-alpha-L-lyxo-hexopyranosyl)-beta-D-glucopyranosyl)oxy)-3-(carbamoylmethyl)-10,19-dichloro-2,3,4,5,6,7,23,24,25,26,36,37,38,38a-tetradecahydro-7,22,28,30,32-pentahydroxy-6-((2R)-4-methyl-2-(methylamino)valeramido)-2,5,24,38,39-pentaoxo-22H-8,11:18,21-dietheno-23,36-(iminomethano)-13,16:31,35-

" Vancomycine; Vancocin; Lyphocin; Vancor 1404-93-9 ≥1050 IU/mg, bio assay 1485.73 C66H75Cl2N9O24 HCl CC1C(C(CC(O1)OC2C(C(C(OC2OC3=C4C=C5C=C3OC6=C(C=C(C=C6)C(C(C(=O)NC(C(=O)NC5C(=O)NC7C8=CC(=C(C=C8)O)C9=C(C=C(C=C9C(NC(=O)C(C(C1=CC(=C(O4)C=C1)Cl)O)NC7=O)C(=O)O)O)O)CC(=O)N)NC(=O)C(CC(C)C)NC)O)Cl)CO)O)O)(C)N)O Hygroscopic Ambient Ambient Soluble in water. Moderately soluble in methanol.  Insoluble in acetone and ether. "Allen CA, Babakhani F, Sears P, et al. Both fidaxomicin and vancomycin inhibit outgrowth of Clostridium difficile spores. Antimicrob Agents Chemother. 2013 Jan;57(1):664-7. PMID: 23147724.

 

Chakraborty SP, Sahu SK, Pramanik P, et al. In vitro antimicrobial activity of nanoconjugated vancomycin against drug resistant Staphylococcus aureus. Int J Pharm. 2012 Oct 15;436(1-2):659-76. PMID: 22841851.

 

Nailor MD, Sobel JD. Antibiotics for gram-positive bacterial infection: vancomycin, teicoplanin, quinupristin/dalfopristin, oxazolidinones, daptomycin, telavancin, and ceftaroline. Med Clin North Am. 2011 Jul;95(4):723-42, vii. PMID: 21679789.

" Not dangerous goods.

LKT C1649 β-Cembrenediol 10 mg 236.6 Diterpene found in Anisomeles. (1S,2E,4R,6R,7E,11E)-2,7,11-Cembratriene-4,6-diol 57605-81-9 ≥98% 306.48 C20H34O2 CC1=CCCC(=CC(CC(C=CC(CC1)C(C)C)(C)O)O)C Ambient -80°C "Kulkarni RR, Shurpali K, Gawde RL, et al. Phyllocladane diterpenes from Anisomeles heyneana. J Asian Nat Prod Res. 2012;14(12):1162-8. PMID: 23157282.

 

Kennedy BS, Nielsen MT, Severson RF. Biorationals from Nicotiana protect cucumbers against Colletotrichum lagenarium (Pass.) ell. & halst disease development. J Chem Ecol. 1995 Feb;21(2):221-31. PMID: 24234021.

" "Not dangerous goods.

"

LKT C1668 Cerivastatin Sodium 10 mg 169.9 Statin; HMG-CoA reductase inhibitor. (3R,5S,6E)-7-[4-(4-Fluorophenyl)-5-(methoxymethyl)-2,6-bis(1-methylethyl)-3-pyridinyl]-3,5-dihydroxy-6- heptenoic acid Baycol; Lipobay; Rivastatin 143201-11-0 ≥98% 481.53 C26H33FNNaO5 CC(C)C1=C(C(=C(C(=N1)C(C)C)C=CC(CC(CC(=O)[O-])O)O)C2=CC=C(C=C2)F)COC.[Na+] Ambient -20°C Soluble in water. "Takeshita Y, Takamura T, Hamaguchi E, et al. Tumor necrosis factor-alpha-induced production of plasminogen activator inhibitor 1 and its regulation by pioglitazone and cerivastatin in a nonmalignant human hepatocyte cell line. Metabolism. 2006 Nov;55(11):1464-72. PMID: 17046548.

 

Schachter M. Chemical, pharmacokinetic and pharmacodynamic properties of statins: an update. Fundam Clin Pharmacol. 2005 Feb;19(1):117-25. PMID: 15660968.

 

Jamal SM, Eisenberg MJ, Christopoulos S. Rhabdomyolysis associated with hydroxymethylglutaryl-coenzyme A reductase inhibitors. Am Heart J. 2004 Jun;147(6):956-65. PMID: 15199341.

 

Viedt C, Shen W, Fei J, et al. HMG-CoA reductase inhibition reduces the proinflammatory activation of human vascular smooth muscle cells by the terminal complement factor C5b-9. Basic Res Cardiol. 2003 Nov;98(6):353-61. PMID: 14556080.

" Not dangerous goods.

LKT C1668 Cerivastatin Sodium 25 mg 339.8 Statin; HMG-CoA reductase inhibitor. (3R,5S,6E)-7-[4-(4-Fluorophenyl)-5-(methoxymethyl)-2,6-bis(1-methylethyl)-3-pyridinyl]-3,5-dihydroxy-6- heptenoic acid Baycol; Lipobay; Rivastatin 143201-11-0 ≥98% 481.53 C26H33FNNaO5 CC(C)C1=C(C(=C(C(=N1)C(C)C)C=CC(CC(CC(=O)[O-])O)O)C2=CC=C(C=C2)F)COC.[Na+] Ambient -20°C Soluble in water. "Takeshita Y, Takamura T, Hamaguchi E, et al. Tumor necrosis factor-alpha-induced production of plasminogen activator inhibitor 1 and its regulation by pioglitazone and cerivastatin in a nonmalignant human hepatocyte cell line. Metabolism. 2006 Nov;55(11):1464-72. PMID: 17046548.

 

Schachter M. Chemical, pharmacokinetic and pharmacodynamic properties of statins: an update. Fundam Clin Pharmacol. 2005 Feb;19(1):117-25. PMID: 15660968.

 

Jamal SM, Eisenberg MJ, Christopoulos S. Rhabdomyolysis associated with hydroxymethylglutaryl-coenzyme A reductase inhibitors. Am Heart J. 2004 Jun;147(6):956-65. PMID: 15199341.

 

Viedt C, Shen W, Fei J, et al. HMG-CoA reductase inhibition reduces the proinflammatory activation of human vascular smooth muscle cells by the terminal complement factor C5b-9. Basic Res Cardiol. 2003 Nov;98(6):353-61. PMID: 14556080.

" Not dangerous goods.

LKT C1718 Cepharanthine, 95% 100 mg 40.7 Alkaloid found in Stephania. 6',12'-Dimethoxy-2,2'-dimethyl-6,7-[methylenebis- (oxy)]oxyacanthan Cepharanthin; O-Methylcepharanoline 481-49-2 ≥95% 606.71 C37H38N2O6 CN1CCC2=CC3=C(C4=C2C1CC5=CC=C(C=C5)OC6=C(C=CC(=C6)CC7C8=CC(=C(C=C8CCN7C)OC)O4)OC)OCO3 Ambient -20°C Soluble in organic solvents except petr ether. "Desgrouas C, Chapus C, Desplans J, et al. In vitro antiplasmodial activity of cepharanthine. Malar J. 2014 Aug 22;13(1):327. PMID: 25145413.

 

Matsuda K, Hattori S, Komizu Y, et al. Cepharanthine inhibited HIV-1 cell-cell transmission and cell-free infection via modification of cell membrane fluidity. Bioorg Med Chem Lett. 2014 May 1;24(9):2115-7. PMID: 24704028.

 

Huang H, Hu G, Wang C, et al. Cepharanthine, an alkaloid from Stephania cepharantha Hayata, inhibits the inflammatory response in the RAW264.7 cell and mouse models. Inflammation. 2014 Feb;37(1):235-46. PMID: 24045962.

 

Chen Z, Huang C, Yang YL, et al. Inhibition of the STAT3 signaling pathway is involved in the antitumor activity of cepharanthine in SaOS2 cells. Acta Pharmacol Sin. 2012 Jan;33(1):101-8. PMID: 22212432.

 

Uthaisar K, Seubwai W, Srikoon P, et al. Cepharanthine suppresses metastatic potential of human cholangiocarcinoma cell lines. Asian Pac J Cancer Prev. 2012;13 Suppl:149-54. PMID: 23480757.

 

Kudo K, Hagiwara S, Hasegawa A, et al. Cepharanthine exerts anti-inflammatory effects via NF-kB inhibition in a LPS-induced rat model of systemic inflammation. J Surg Res. 2011 Nov;171(1):199-204. PMID: 20334881.

" Not dangerous goods.

LKT C1718 Cepharanthine, 95% 500 mg 101.9 Alkaloid found in Stephania. 6',12'-Dimethoxy-2,2'-dimethyl-6,7-[methylenebis- (oxy)]oxyacanthan Cepharanthin; O-Methylcepharanoline 481-49-2 ≥95% 606.71 C37H38N2O6 CN1CCC2=CC3=C(C4=C2C1CC5=CC=C(C=C5)OC6=C(C=CC(=C6)CC7C8=CC(=C(C=C8CCN7C)OC)O4)OC)OCO3 Ambient -20°C Soluble in organic solvents except petr ether. "Desgrouas C, Chapus C, Desplans J, et al. In vitro antiplasmodial activity of cepharanthine. Malar J. 2014 Aug 22;13(1):327. PMID: 25145413.

 

Matsuda K, Hattori S, Komizu Y, et al. Cepharanthine inhibited HIV-1 cell-cell transmission and cell-free infection via modification of cell membrane fluidity. Bioorg Med Chem Lett. 2014 May 1;24(9):2115-7. PMID: 24704028.

 

Huang H, Hu G, Wang C, et al. Cepharanthine, an alkaloid from Stephania cepharantha Hayata, inhibits the inflammatory response in the RAW264.7 cell and mouse models. Inflammation. 2014 Feb;37(1):235-46. PMID: 24045962.

 

Chen Z, Huang C, Yang YL, et al. Inhibition of the STAT3 signaling pathway is involved in the antitumor activity of cepharanthine in SaOS2 cells. Acta Pharmacol Sin. 2012 Jan;33(1):101-8. PMID: 22212432.

 

Uthaisar K, Seubwai W, Srikoon P, et al. Cepharanthine suppresses metastatic potential of human cholangiocarcinoma cell lines. Asian Pac J Cancer Prev. 2012;13 Suppl:149-54. PMID: 23480757.

 

Kudo K, Hagiwara S, Hasegawa A, et al. Cepharanthine exerts anti-inflammatory effects via NF-kB inhibition in a LPS-induced rat model of systemic inflammation. J Surg Res. 2011 Nov;171(1):199-204. PMID: 20334881.

" Not dangerous goods.

LKT C1718 Cepharanthine, 95% 1 g 163.2 Alkaloid found in Stephania. 6',12'-Dimethoxy-2,2'-dimethyl-6,7-[methylenebis- (oxy)]oxyacanthan Cepharanthin; O-Methylcepharanoline 481-49-2 ≥95% 606.71 C37H38N2O6 CN1CCC2=CC3=C(C4=C2C1CC5=CC=C(C=C5)OC6=C(C=CC(=C6)CC7C8=CC(=C(C=C8CCN7C)OC)O4)OC)OCO3 Ambient -20°C Soluble in organic solvents except petr ether. "Desgrouas C, Chapus C, Desplans J, et al. In vitro antiplasmodial activity of cepharanthine. Malar J. 2014 Aug 22;13(1):327. PMID: 25145413.

 

Matsuda K, Hattori S, Komizu Y, et al. Cepharanthine inhibited HIV-1 cell-cell transmission and cell-free infection via modification of cell membrane fluidity. Bioorg Med Chem Lett. 2014 May 1;24(9):2115-7. PMID: 24704028.

 

Huang H, Hu G, Wang C, et al. Cepharanthine, an alkaloid from Stephania cepharantha Hayata, inhibits the inflammatory response in the RAW264.7 cell and mouse models. Inflammation. 2014 Feb;37(1):235-46. PMID: 24045962.

 

Chen Z, Huang C, Yang YL, et al. Inhibition of the STAT3 signaling pathway is involved in the antitumor activity of cepharanthine in SaOS2 cells. Acta Pharmacol Sin. 2012 Jan;33(1):101-8. PMID: 22212432.

 

Uthaisar K, Seubwai W, Srikoon P, et al. Cepharanthine suppresses metastatic potential of human cholangiocarcinoma cell lines. Asian Pac J Cancer Prev. 2012;13 Suppl:149-54. PMID: 23480757.

 

Kudo K, Hagiwara S, Hasegawa A, et al. Cepharanthine exerts anti-inflammatory effects via NF-kB inhibition in a LPS-induced rat model of systemic inflammation. J Surg Res. 2011 Nov;171(1):199-204. PMID: 20334881.

" Not dangerous goods.

LKT V0245 Valdecoxib 5 mg 88.3 NSAID; CB1 agonist, COX-2 inhibitor. 181695-72-7 ≥98% 314.36 C16H14N2O3S CC1=C(C(=NO1)C2=CC=CC=C2)C3=CC=C(C=C3)S(=O)(=O)N Ambient Ambient Water 0.5 mg/ml "Atukorala I, Hunter DJ. Valdecoxib : the rise and fall of a COX-2 inhibitor. Expert Opin Pharmacother. 2013 Jun;14(8):1077-86. PMID: 23517091.

 

Schröder H, Höllt V, Becker A. Parecoxib and its metabolite valdecoxib directly interact with cannabinoid binding sites in CB1-expressing HEK 293 cells and rat brain tissue. Neurochem Int. 2011 Jan;58(1):9-13. PMID: 21073910.

 

Roumie CL, Choma NN, Kaltenbach L, et al. Non-aspirin NSAIDs, cyclooxygenase-2 inhibitors and risk for cardiovascular events-stroke, acute myocardial infarction, and death from coronary heart disease. Pharmacoepidemiol Drug Saf. 2009 Nov;18(11):1053-63. PMID: 19637402.

 

Benetello V, Sakamoto FC, Giglio FP, et al. The selective and non-selective cyclooxygenase inhibitors valdecoxib and piroxicam induce the same postoperative analgesia and control of trismus and swelling after lower third molar removal. Braz J Med Biol Res. 2007 Aug;40(8):1133-40. PMID: 17665051.

 

Dogné JM, Thiry A, Pratico D, et al. Dual carbonic anhydrase--cyclooxygenase-2 inhibitors. Curr Top Med Chem. 2007;7(9):885-91. PMID: 17504133.

 

Walker MC, Kurumbail RG, Kiefer JR, et al. A three-step kinetic mechanism for selective inhibition of cyclo-oxygenase-2 by diarylheterocyclic inhibitors. Biochem J. 2001 Aug 1;357(Pt 3):709-18. PMID: 11463341.

" None Not dangerous goods.

LKT V0245 Valdecoxib 10 mg 163.2 NSAID; CB1 agonist, COX-2 inhibitor. 181695-72-7 ≥98% 314.36 C16H14N2O3S CC1=C(C(=NO1)C2=CC=CC=C2)C3=CC=C(C=C3)S(=O)(=O)N Ambient Ambient Water 0.5 mg/ml "Atukorala I, Hunter DJ. Valdecoxib : the rise and fall of a COX-2 inhibitor. Expert Opin Pharmacother. 2013 Jun;14(8):1077-86. PMID: 23517091.

 

Schröder H, Höllt V, Becker A. Parecoxib and its metabolite valdecoxib directly interact with cannabinoid binding sites in CB1-expressing HEK 293 cells and rat brain tissue. Neurochem Int. 2011 Jan;58(1):9-13. PMID: 21073910.

 

Roumie CL, Choma NN, Kaltenbach L, et al. Non-aspirin NSAIDs, cyclooxygenase-2 inhibitors and risk for cardiovascular events-stroke, acute myocardial infarction, and death from coronary heart disease. Pharmacoepidemiol Drug Saf. 2009 Nov;18(11):1053-63. PMID: 19637402.

 

Benetello V, Sakamoto FC, Giglio FP, et al. The selective and non-selective cyclooxygenase inhibitors valdecoxib and piroxicam induce the same postoperative analgesia and control of trismus and swelling after lower third molar removal. Braz J Med Biol Res. 2007 Aug;40(8):1133-40. PMID: 17665051.

 

Dogné JM, Thiry A, Pratico D, et al. Dual carbonic anhydrase--cyclooxygenase-2 inhibitors. Curr Top Med Chem. 2007;7(9):885-91. PMID: 17504133.

 

Walker MC, Kurumbail RG, Kiefer JR, et al. A three-step kinetic mechanism for selective inhibition of cyclo-oxygenase-2 by diarylheterocyclic inhibitors. Biochem J. 2001 Aug 1;357(Pt 3):709-18. PMID: 11463341.

" None Not dangerous goods.

LKT V0245 Valdecoxib 25 mg 339.8 NSAID; CB1 agonist, COX-2 inhibitor. 181695-72-7 ≥98% 314.36 C16H14N2O3S CC1=C(C(=NO1)C2=CC=CC=C2)C3=CC=C(C=C3)S(=O)(=O)N Ambient Ambient Water 0.5 mg/ml "Atukorala I, Hunter DJ. Valdecoxib : the rise and fall of a COX-2 inhibitor. Expert Opin Pharmacother. 2013 Jun;14(8):1077-86. PMID: 23517091.

 

Schröder H, Höllt V, Becker A. Parecoxib and its metabolite valdecoxib directly interact with cannabinoid binding sites in CB1-expressing HEK 293 cells and rat brain tissue. Neurochem Int. 2011 Jan;58(1):9-13. PMID: 21073910.

 

Roumie CL, Choma NN, Kaltenbach L, et al. Non-aspirin NSAIDs, cyclooxygenase-2 inhibitors and risk for cardiovascular events-stroke, acute myocardial infarction, and death from coronary heart disease. Pharmacoepidemiol Drug Saf. 2009 Nov;18(11):1053-63. PMID: 19637402.

 

Benetello V, Sakamoto FC, Giglio FP, et al. The selective and non-selective cyclooxygenase inhibitors valdecoxib and piroxicam induce the same postoperative analgesia and control of trismus and swelling after lower third molar removal. Braz J Med Biol Res. 2007 Aug;40(8):1133-40. PMID: 17665051.

 

Dogné JM, Thiry A, Pratico D, et al. Dual carbonic anhydrase--cyclooxygenase-2 inhibitors. Curr Top Med Chem. 2007;7(9):885-91. PMID: 17504133.

 

Walker MC, Kurumbail RG, Kiefer JR, et al. A three-step kinetic mechanism for selective inhibition of cyclo-oxygenase-2 by diarylheterocyclic inhibitors. Biochem J. 2001 Aug 1;357(Pt 3):709-18. PMID: 11463341.

" None Not dangerous goods.

LKT C1867 Ceramide 5 mg 76.4 Endogenous sphingosine-based lipid, component of sphingomyelin required for cell membrane lipid bilayer production. N-Palmitoyl-D-Sphingosine; N-Hexadecanoyl-D- sphingosine; Palmitoyl Ceramide;D-erythro-Sphingosine, N-Palmitoyl- 24696-26-2 ≥98% 537.9 C16 (C34H67NO3) CCCCCCCCCCCCCCCC(=O)NC(CO)C(C=CCCCCCCCCCCCCC)O Ambient -20°C Soluble in warm ethanol and isopropanol. "Hannun YA, Obeid LM. Principles of bioactive lipid signalling: lessons from sphingolipids. Nat Rev Mol Cell Biol. 2008 Feb;9(2):139-50. PMID: 18216770.

 

Wu D, Ren Z, Pae M, et al. Aging up-regulates expression of inflammatory mediators in mouse adipose tissue. J Immunol. 2007 Oct 1;179(7):4829-39. PMID: 17878382.

 

Haimovitz-Friedman A, Kan CC, Ehleiter D, et al. Ionizing radiation acts on cellular membranes to generate ceramide and initiate apoptosis. J Exp Med. 1994 Aug 1;180(2):525-35. PMID: 8046331.

" Not dangerous goods.

LKT C1867 Ceramide 25 mg 365.2 Endogenous sphingosine-based lipid, component of sphingomyelin required for cell membrane lipid bilayer production. N-Palmitoyl-D-Sphingosine; N-Hexadecanoyl-D- sphingosine; Palmitoyl Ceramide;D-erythro-Sphingosine, N-Palmitoyl- 24696-26-2 ≥98% 537.9 C16 (C34H67NO3) CCCCCCCCCCCCCCCC(=O)NC(CO)C(C=CCCCCCCCCCCCCC)O Ambient -20°C Soluble in warm ethanol and isopropanol. "Hannun YA, Obeid LM. Principles of bioactive lipid signalling: lessons from sphingolipids. Nat Rev Mol Cell Biol. 2008 Feb;9(2):139-50. PMID: 18216770.

 

Wu D, Ren Z, Pae M, et al. Aging up-regulates expression of inflammatory mediators in mouse adipose tissue. J Immunol. 2007 Oct 1;179(7):4829-39. PMID: 17878382.

 

Haimovitz-Friedman A, Kan CC, Ehleiter D, et al. Ionizing radiation acts on cellular membranes to generate ceramide and initiate apoptosis. J Exp Med. 1994 Aug 1;180(2):525-35. PMID: 8046331.

" Not dangerous goods.

LKT V0160 Vapreotide 0.5 mg 132 Synthetic somatostatin analog, peptide; somatostatin 2 agonist, NK1 antagonist. "L-Tryptophanamide, D-phenylalanyl-L-cysteinyl-L-tyrosyl-D-

tryptophyl-L-lysyl-L-valyl-L-cysteinyl-, cyclic (2->7)-" Sanvar IR; BMY 41606; RC 160 103222-11-3 ≥95% 1131.4 C57H70N12O9S2 CC(C)C1C(=O)NC(CSSCC(C(=O)NC(C(=O)NC(C(=O)NC(C(=O)N1)CCCCN)CC2=CNC3=CC=CC=C32)CC4=CC=C(C=C4)O)NC(=O)C(CC5=CC=CC=C5)N)C(=O)NC(CC6=CNC7=CC=CC=C76)C(=O)N Ambient -20°C "Spitsin S, Tuluc F, Meshki J, et al. Analog of somatostatin vapreotide exhibits biological effects in vitro via interaction with neurokinin-1 receptor. Neuroimmunomodulation. 2013;20(5):247-55. PMID: 23921645.

 

Tachibana T, Cline MA, Khan MS, et al. Feeding responses to central administration of several somatostatin analogs in chicks. Comp Biochem Physiol A Mol Integr Physiol. 2011 Jan;158(1):47-51. PMID: 20826222.

 

Calès P. Vapreotide acetate for the treatment of esophageal variceal bleeding. Expert Rev Gastroenterol Hepatol. 2008 Apr;2(2):185-92. PMID: 19072353.

 

González-Barcena D, Schally AV, Vadillo-Buenfil M, et al. Response of patients with advanced prostatic cancer to administration of somatostatin analog RC-160 (vapreotide) at the time of relapse. Prostate. 2003 Aug 1;56(3):183-91. PMID: 12772187.

" Not dangerous goods.

LKT V0160 Vapreotide 1 mg 225 Synthetic somatostatin analog, peptide; somatostatin 2 agonist, NK1 antagonist. "L-Tryptophanamide, D-phenylalanyl-L-cysteinyl-L-tyrosyl-D-

tryptophyl-L-lysyl-L-valyl-L-cysteinyl-, cyclic (2->7)-" Sanvar IR; BMY 41606; RC 160 103222-11-3 ≥95% 1131.4 C57H70N12O9S2 CC(C)C1C(=O)NC(CSSCC(C(=O)NC(C(=O)NC(C(=O)NC(C(=O)N1)CCCCN)CC2=CNC3=CC=CC=C32)CC4=CC=C(C=C4)O)NC(=O)C(CC5=CC=CC=C5)N)C(=O)NC(CC6=CNC7=CC=CC=C76)C(=O)N Ambient -20°C "Spitsin S, Tuluc F, Meshki J, et al. Analog of somatostatin vapreotide exhibits biological effects in vitro via interaction with neurokinin-1 receptor. Neuroimmunomodulation. 2013;20(5):247-55. PMID: 23921645.

 

Tachibana T, Cline MA, Khan MS, et al. Feeding responses to central administration of several somatostatin analogs in chicks. Comp Biochem Physiol A Mol Integr Physiol. 2011 Jan;158(1):47-51. PMID: 20826222.

 

Calès P. Vapreotide acetate for the treatment of esophageal variceal bleeding. Expert Rev Gastroenterol Hepatol. 2008 Apr;2(2):185-92. PMID: 19072353.

 

González-Barcena D, Schally AV, Vadillo-Buenfil M, et al. Response of patients with advanced prostatic cancer to administration of somatostatin analog RC-160 (vapreotide) at the time of relapse. Prostate. 2003 Aug 1;56(3):183-91. PMID: 12772187.

" Not dangerous goods.

LKT V0160 Vapreotide 2.5 mg 396.1 Synthetic somatostatin analog, peptide; somatostatin 2 agonist, NK1 antagonist. "L-Tryptophanamide, D-phenylalanyl-L-cysteinyl-L-tyrosyl-D-

tryptophyl-L-lysyl-L-valyl-L-cysteinyl-, cyclic (2->7)-" Sanvar IR; BMY 41606; RC 160 103222-11-3 ≥95% 1131.4 C57H70N12O9S2 CC(C)C1C(=O)NC(CSSCC(C(=O)NC(C(=O)NC(C(=O)NC(C(=O)N1)CCCCN)CC2=CNC3=CC=CC=C32)CC4=CC=C(C=C4)O)NC(=O)C(CC5=CC=CC=C5)N)C(=O)NC(CC6=CNC7=CC=CC=C76)C(=O)N Ambient -20°C "Spitsin S, Tuluc F, Meshki J, et al. Analog of somatostatin vapreotide exhibits biological effects in vitro via interaction with neurokinin-1 receptor. Neuroimmunomodulation. 2013;20(5):247-55. PMID: 23921645.

 

Tachibana T, Cline MA, Khan MS, et al. Feeding responses to central administration of several somatostatin analogs in chicks. Comp Biochem Physiol A Mol Integr Physiol. 2011 Jan;158(1):47-51. PMID: 20826222.

 

Calès P. Vapreotide acetate for the treatment of esophageal variceal bleeding. Expert Rev Gastroenterol Hepatol. 2008 Apr;2(2):185-92. PMID: 19072353.

 

González-Barcena D, Schally AV, Vadillo-Buenfil M, et al. Response of patients with advanced prostatic cancer to administration of somatostatin analog RC-160 (vapreotide) at the time of relapse. Prostate. 2003 Aug 1;56(3):183-91. PMID: 12772187.

" Not dangerous goods.

LKT C1868 Cerebellin 1 mg 240.1 Peptide, involved in synapse formation and cell adhesion. 94071-26-8 ≥95% 1632.81 C69H113N23O23 CCC(C)C(C(=O)NC(CCCN=C(N)N)C(=O)NC(CO)C(=O)NC(C(C)O)C(=O)NC(CC(=O)N)C(=O)NC(CC1=CN=CN1)C(=O)O)NC(=O)C(C)NC(=O)C(CO)NC(=O)C(CC2=CC=CC=C2)NC(=O)C(C)NC(=O)C(C(C)C)NC(=O)C(CCCCN)NC(=O)C(C)NC(=O)C(CO)NC(=O)CNC(=O)C(CO)N Ambient -20°C soluble in water "Lee SJ, Uemura T, Yoshida T, et al. GluRδ2 assembles four neurexins into trans-synaptic triad to trigger synapse formation. J Neurosci. 2012 Mar 28;32(13):4688-701. PMID: 22457515.

 

Rong Y, Wei P, Parris J, et al. Comparison of Cbln1 and Cbln2 functions using transgenic and knockout mice. J Neurochem. 2012 Feb;120(4):528-40. PMID: 22117778.

" Not dangerous goods.

LKT C1868 Cerebellin 2 mg 407.9 Peptide, involved in synapse formation and cell adhesion. 94071-26-8 ≥95% 1632.81 C69H113N23O23 CCC(C)C(C(=O)NC(CCCN=C(N)N)C(=O)NC(CO)C(=O)NC(C(C)O)C(=O)NC(CC(=O)N)C(=O)NC(CC1=CN=CN1)C(=O)O)NC(=O)C(C)NC(=O)C(CO)NC(=O)C(CC2=CC=CC=C2)NC(=O)C(C)NC(=O)C(C(C)C)NC(=O)C(CCCCN)NC(=O)C(C)NC(=O)C(CO)NC(=O)CNC(=O)C(CO)N Ambient -20°C soluble in water "Lee SJ, Uemura T, Yoshida T, et al. GluRδ2 assembles four neurexins into trans-synaptic triad to trigger synapse formation. J Neurosci. 2012 Mar 28;32(13):4688-701. PMID: 22457515.

 

Rong Y, Wei P, Parris J, et al. Comparison of Cbln1 and Cbln2 functions using transgenic and knockout mice. J Neurochem. 2012 Feb;120(4):528-40. PMID: 22117778.

" Not dangerous goods.

LKT C1868 Cerebellin 5 mg 720.2 Peptide, involved in synapse formation and cell adhesion. 94071-26-8 ≥95% 1632.81 C69H113N23O23 CCC(C)C(C(=O)NC(CCCN=C(N)N)C(=O)NC(CO)C(=O)NC(C(C)O)C(=O)NC(CC(=O)N)C(=O)NC(CC1=CN=CN1)C(=O)O)NC(=O)C(C)NC(=O)C(CO)NC(=O)C(CC2=CC=CC=C2)NC(=O)C(C)NC(=O)C(C(C)C)NC(=O)C(CCCCN)NC(=O)C(C)NC(=O)C(CO)NC(=O)CNC(=O)C(CO)N Ambient -20°C soluble in water "Lee SJ, Uemura T, Yoshida T, et al. GluRδ2 assembles four neurexins into trans-synaptic triad to trigger synapse formation. J Neurosci. 2012 Mar 28;32(13):4688-701. PMID: 22457515.

 

Rong Y, Wei P, Parris J, et al. Comparison of Cbln1 and Cbln2 functions using transgenic and knockout mice. J Neurochem. 2012 Feb;120(4):528-40. PMID: 22117778.

" Not dangerous goods.

LKT C1869 Cerulenin 1 mg 66.4 Found in Cephalosporium; fatty acid synthase inhibitor. (2R,3S)-3-[(4E,7E)-1-Oxo-4,7-nonadienyl]oxirane- carboxamide Helicocerin 17397-89-6 ≥98% 223.27 C12H17NO3 CC=CCC=CCCC(=O)C1C(O1)C(=O)N Ambient -20°C Soluble in ethanol, acetone, or benzene. Slightly soluble in water. "Straub SG, Sharp GW. Inhibition of insulin secretion by cerulenin might be due to impaired glucose metabolism. Diabetes Metab Res Rev. 2007 Feb;23(2):146-51. PMID: 16705622.

 

Price AC, Choi KH, Heath RJ, et al. Inhibition of beta-ketoacyl-acyl carrier protein synthases by thiolactomycin and cerulenin. Structure and mechanism. J Biol Chem. 2001 Mar 2;276(9):6551-9. PMID: 11050088.

 

Huang P, Zhu S, Lu S, et al. Cerulenin inhibits growth of human colonic carcinoma in nude mice. Zhonghua Bing Li Xue Za Zhi. 2000 Dec;29(6):435-8. PMID: 11866947.

" Xn Not dangerous goods.

LKT C1869 Cerulenin 5 mg 173 Found in Cephalosporium; fatty acid synthase inhibitor. (2R,3S)-3-[(4E,7E)-1-Oxo-4,7-nonadienyl]oxirane- carboxamide Helicocerin 17397-89-6 ≥98% 223.27 C12H17NO3 CC=CCC=CCCC(=O)C1C(O1)C(=O)N Ambient -20°C Soluble in ethanol, acetone, or benzene. Slightly soluble in water. "Straub SG, Sharp GW. Inhibition of insulin secretion by cerulenin might be due to impaired glucose metabolism. Diabetes Metab Res Rev. 2007 Feb;23(2):146-51. PMID: 16705622.

 

Price AC, Choi KH, Heath RJ, et al. Inhibition of beta-ketoacyl-acyl carrier protein synthases by thiolactomycin and cerulenin. Structure and mechanism. J Biol Chem. 2001 Mar 2;276(9):6551-9. PMID: 11050088.

 

Huang P, Zhu S, Lu S, et al. Cerulenin inhibits growth of human colonic carcinoma in nude mice. Zhonghua Bing Li Xue Za Zhi. 2000 Dec;29(6):435-8. PMID: 11866947.

" Xn Not dangerous goods.

LKT C1869 Cerulenin 10 mg 288.3 Found in Cephalosporium; fatty acid synthase inhibitor. (2R,3S)-3-[(4E,7E)-1-Oxo-4,7-nonadienyl]oxirane- carboxamide Helicocerin 17397-89-6 ≥98% 223.27 C12H17NO3 CC=CCC=CCCC(=O)C1C(O1)C(=O)N Ambient -20°C Soluble in ethanol, acetone, or benzene. Slightly soluble in water. "Straub SG, Sharp GW. Inhibition of insulin secretion by cerulenin might be due to impaired glucose metabolism. Diabetes Metab Res Rev. 2007 Feb;23(2):146-51. PMID: 16705622.

 

Price AC, Choi KH, Heath RJ, et al. Inhibition of beta-ketoacyl-acyl carrier protein synthases by thiolactomycin and cerulenin. Structure and mechanism. J Biol Chem. 2001 Mar 2;276(9):6551-9. PMID: 11050088.

 

Huang P, Zhu S, Lu S, et al. Cerulenin inhibits growth of human colonic carcinoma in nude mice. Zhonghua Bing Li Xue Za Zhi. 2000 Dec;29(6):435-8. PMID: 11866947.

" Xn Not dangerous goods.

LKT C1876 Cetirizine Dihydrochloride 5 g 90.5 Histamine H1 antagonist. 2-[2-[4-[(4-chlorophenyl)-phenyl-methyl]piperazin-1-yl]ethoxy]acetic acid 83881-52-1 ≥99% 461.82 C21H25ClN2O3 2HCl C1CN(CCN1CCOCC(=O)O)C(C2=CC=CC=C2)C3=CC=C(C=C3)Cl.Cl.Cl Ambient Ambient Soluble in water & Methanol "Namazi MR. Cetirizine and allopurinol as novel weapons against cellular autoimmune disorders. Int Immunopharmacol. 2004 Mar;4(3):349-53. PMID: 15037212.

 

Bruno G, Andreozzi P, Magrini L, et al. Serum tryptase in allergic rhinitis: effect of cetirizine treatment. Int J Immunopathol Pharmacol. 2001 Sep-Dec;14(3):147-152. PMID: 12604015.

 

Slater JW, Zechnich AD, Haxby DG. Second-generation antihistamines: a comparative review. Drugs. 1999 Jan;57(1):31-47. PMID: 9951950.

" Xn Not Dangerous Goods

LKT V0153 Vanilloid Receptor 1 Fragment 1 mg 192.3 Peptide fragment of TRPV1. Transient receptor potential vanilloid 1; TRPV1; VR1, capsaicin receptor ≥95% 1782.96 C75H117N18O28S2 Ambient -20°C "Anwar IJ, Derbenev AV. TRPV1-dependent regulation of synaptic activity in the mouse dorsal motor nucleus of the vagus nerve. Front Neurosci. 2013 Dec 13;7:238. PMID: 24379754.

 

Tóth A, Czikora A, Pásztor ET, et al. Vanilloid Receptor-1 (TRPV1) Expression and Function in the Vasculature of the Rat. J Histochem Cytochem. 2013 Dec 5. [Epub ahead of print]. PMID: 24217926.

 

Kelly S, Chapman RJ, Woodhams S, et al. Increased function of pronociceptive TRPV1 at the level of the joint in a rat model of osteoarthritis pain. Ann Rheum Dis. 2013 Oct 23. [Epub ahead of print]. PMID: 24152419.

"

LKT C1876 Cetirizine Dihydrochloride 10 g 144 Histamine H1 antagonist. 2-[2-[4-[(4-chlorophenyl)-phenyl-methyl]piperazin-1-yl]ethoxy]acetic acid 83881-52-1 ≥99% 461.82 C21H25ClN2O3 2HCl C1CN(CCN1CCOCC(=O)O)C(C2=CC=CC=C2)C3=CC=C(C=C3)Cl.Cl.Cl Ambient Ambient Soluble in water & Methanol "Namazi MR. Cetirizine and allopurinol as novel weapons against cellular autoimmune disorders. Int Immunopharmacol. 2004 Mar;4(3):349-53. PMID: 15037212.

 

Bruno G, Andreozzi P, Magrini L, et al. Serum tryptase in allergic rhinitis: effect of cetirizine treatment. Int J Immunopathol Pharmacol. 2001 Sep-Dec;14(3):147-152. PMID: 12604015.

 

Slater JW, Zechnich AD, Haxby DG. Second-generation antihistamines: a comparative review. Drugs. 1999 Jan;57(1):31-47. PMID: 9951950.

" Xn Not Dangerous Goods

LKT C1876 Cetirizine Dihydrochloride 25 g 251.3 Histamine H1 antagonist. 2-[2-[4-[(4-chlorophenyl)-phenyl-methyl]piperazin-1-yl]ethoxy]acetic acid 83881-52-1 ≥99% 461.82 C21H25ClN2O3 2HCl C1CN(CCN1CCOCC(=O)O)C(C2=CC=CC=C2)C3=CC=C(C=C3)Cl.Cl.Cl Ambient Ambient Soluble in water & Methanol "Namazi MR. Cetirizine and allopurinol as novel weapons against cellular autoimmune disorders. Int Immunopharmacol. 2004 Mar;4(3):349-53. PMID: 15037212.

 

Bruno G, Andreozzi P, Magrini L, et al. Serum tryptase in allergic rhinitis: effect of cetirizine treatment. Int J Immunopathol Pharmacol. 2001 Sep-Dec;14(3):147-152. PMID: 12604015.

 

Slater JW, Zechnich AD, Haxby DG. Second-generation antihistamines: a comparative review. Drugs. 1999 Jan;57(1):31-47. PMID: 9951950.

" Xn Not Dangerous Goods

LKT V0153 Vanilloid Receptor 1 Fragment 2 mg 327.1 Peptide fragment of TRPV1. Transient receptor potential vanilloid 1; TRPV1; VR1, capsaicin receptor ≥95% 1782.96 C75H117N18O28S2 Ambient -20°C "Anwar IJ, Derbenev AV. TRPV1-dependent regulation of synaptic activity in the mouse dorsal motor nucleus of the vagus nerve. Front Neurosci. 2013 Dec 13;7:238. PMID: 24379754.

 

Tóth A, Czikora A, Pásztor ET, et al. Vanilloid Receptor-1 (TRPV1) Expression and Function in the Vasculature of the Rat. J Histochem Cytochem. 2013 Dec 5. [Epub ahead of print]. PMID: 24217926.

 

Kelly S, Chapman RJ, Woodhams S, et al. Increased function of pronociceptive TRPV1 at the level of the joint in a rat model of osteoarthritis pain. Ann Rheum Dis. 2013 Oct 23. [Epub ahead of print]. PMID: 24152419.

"

LKT V0153 Vanilloid Receptor 1 Fragment 5 mg 576.1 Peptide fragment of TRPV1. Transient receptor potential vanilloid 1; TRPV1; VR1, capsaicin receptor ≥95% 1782.96 C75H117N18O28S2 Ambient -20°C "Anwar IJ, Derbenev AV. TRPV1-dependent regulation of synaptic activity in the mouse dorsal motor nucleus of the vagus nerve. Front Neurosci. 2013 Dec 13;7:238. PMID: 24379754.

 

Tóth A, Czikora A, Pásztor ET, et al. Vanilloid Receptor-1 (TRPV1) Expression and Function in the Vasculature of the Rat. J Histochem Cytochem. 2013 Dec 5. [Epub ahead of print]. PMID: 24217926.

 

Kelly S, Chapman RJ, Woodhams S, et al. Increased function of pronociceptive TRPV1 at the level of the joint in a rat model of osteoarthritis pain. Ann Rheum Dis. 2013 Oct 23. [Epub ahead of print]. PMID: 24152419.

"

LKT C1878 Cetrimide 50 g 62.5 Mixture of quaternary ammonium salts, cationic detergent; H+ ATP synthase inhibitor. N,N,N-Trimethyl-1-hexadecanaminium bromide Cetrimonium Bromide; Bromat; Cetab; Lissolamine V; Micol; Quamonium, Hexadecyltrimethylammonium bromide 57-09-0 ≥98% 364.45 C19H42BrN CCCCCCCCCCCCCCCC[N+](C)(C)C.[Br-] Ambient Ambient Soluble in 1 M water at 20oC. Sparingly soluble in acetone. "Ito E, Yip KW, Katz D, et al. Potential use of cetrimonium bromide as an apoptosis-promoting anticancer agent for head and neck cancer. Mol Pharmacol. 2009 Nov;76(5):969-83. PMID: 19654225.

 

Bragadin M, Dell'Antone P. Mitochondrial bioenergetics as affected by cationic detergents. Arch Environ Contam Toxicol. 1996 Feb;30(2):280-4. PMID: 8593085.

" Xn, Xi, N "UN number: 3077     Class: 9     Packing Group: III

Proper shipping name: Environmentally hazardous substance, solid, n.o.s. (Cetrimide)

Marine pollutant: Yes     Poison Inhalation Hazard: Yes"

LKT C1878 Cetrimide 250 g 219.7 Mixture of quaternary ammonium salts, cationic detergent; H+ ATP synthase inhibitor. N,N,N-Trimethyl-1-hexadecanaminium bromide Cetrimonium Bromide; Bromat; Cetab; Lissolamine V; Micol; Quamonium, Hexadecyltrimethylammonium bromide 57-09-0 ≥98% 364.45 C19H42BrN CCCCCCCCCCCCCCCC[N+](C)(C)C.[Br-] Ambient Ambient Soluble in 1 M water at 20oC. Sparingly soluble in acetone. "Ito E, Yip KW, Katz D, et al. Potential use of cetrimonium bromide as an apoptosis-promoting anticancer agent for head and neck cancer. Mol Pharmacol. 2009 Nov;76(5):969-83. PMID: 19654225.

 

Bragadin M, Dell'Antone P. Mitochondrial bioenergetics as affected by cationic detergents. Arch Environ Contam Toxicol. 1996 Feb;30(2):280-4. PMID: 8593085.

" Xn, Xi, N "UN number: 3077     Class: 9     Packing Group: III

Proper shipping name: Environmentally hazardous substance, solid, n.o.s. (Cetrimide)

Marine pollutant: Yes     Poison Inhalation Hazard: Yes"

LKT V0147 Valproic Acid Sodium 10 g 29.9 T-type Ca2+ and voltage-gated Na+ channel blocker, GABA transaminase and HDAC inhibitor. Sodium 2-propylpentanoate; Sodium valproate; 2-Propylpentanoic acid sodium salt 1069-66-5 ≥98% 166.19 C8H15NaO2 CCCC(CCC)C(=O)[O-].[Na+] Ambient Ambient "Water (50 mg/ml)

Ethanol (30 mg/ml)

DMSO (5 mg/ml)

DMF (5 mg/ml)" "Zhang ZH, Hao CL, Liu P, et al. Valproic acid inhibits tumor angiogenesis in mice transplanted with Kasumi 1 leukemia cells. Mol Med Rep. 2014 Feb;9(2):443-9. PMID: 24297248.

 

Ji MH, Li GM, Jia M, et al. Valproic acid attenuates lipopolysaccharide-induced acute lung injury in mice. Inflammation. 2013 Dec;36(6):1453-9. PMID: 23846716.

 

Zhao L, Chen CN, Hajji N, et al. Histone deacetylation inhibition in pulmonary hypertension: therapeutic potential of valproic acid and suberoylanilide hydroxamic acid. Circulation. 2012 Jul 24;126(4):455-67. PMID: 22711276.

 

Rosenberg G. The mechanisms of action of valproate in neuropsychiatric disorders: can we see the forest for the trees? Cell Mol Life Sci. 2007 Aug;64(16):2090-103. PMID: 17514356.

 

Kelly KM, Gross RA, Macdonald RL. Valproic acid selectively reduces the low-threshold (T) calcium current in rat nodose neurons. Neurosci Lett. 1990 Aug 14;116(1-2):233-8. PMID: 2175404.

" Xn, T, Xi, Repr. Not dangerous goods.

LKT V0147 Valproic Acid Sodium 25 g 70.7 T-type Ca2+ and voltage-gated Na+ channel blocker, GABA transaminase and HDAC inhibitor. Sodium 2-propylpentanoate; Sodium valproate; 2-Propylpentanoic acid sodium salt 1069-66-5 ≥98% 166.19 C8H15NaO2 CCCC(CCC)C(=O)[O-].[Na+] Ambient Ambient "Water (50 mg/ml)

Ethanol (30 mg/ml)

DMSO (5 mg/ml)

DMF (5 mg/ml)" "Zhang ZH, Hao CL, Liu P, et al. Valproic acid inhibits tumor angiogenesis in mice transplanted with Kasumi 1 leukemia cells. Mol Med Rep. 2014 Feb;9(2):443-9. PMID: 24297248.

 

Ji MH, Li GM, Jia M, et al. Valproic acid attenuates lipopolysaccharide-induced acute lung injury in mice. Inflammation. 2013 Dec;36(6):1453-9. PMID: 23846716.

 

Zhao L, Chen CN, Hajji N, et al. Histone deacetylation inhibition in pulmonary hypertension: therapeutic potential of valproic acid and suberoylanilide hydroxamic acid. Circulation. 2012 Jul 24;126(4):455-67. PMID: 22711276.

 

Rosenberg G. The mechanisms of action of valproate in neuropsychiatric disorders: can we see the forest for the trees? Cell Mol Life Sci. 2007 Aug;64(16):2090-103. PMID: 17514356.

 

Kelly KM, Gross RA, Macdonald RL. Valproic acid selectively reduces the low-threshold (T) calcium current in rat nodose neurons. Neurosci Lett. 1990 Aug 14;116(1-2):233-8. PMID: 2175404.

" Xn, T, Xi, Repr. Not dangerous goods.

LKT V0147 Valproic Acid Sodium 100 g 203.8 T-type Ca2+ and voltage-gated Na+ channel blocker, GABA transaminase and HDAC inhibitor. Sodium 2-propylpentanoate; Sodium valproate; 2-Propylpentanoic acid sodium salt 1069-66-5 ≥98% 166.19 C8H15NaO2 CCCC(CCC)C(=O)[O-].[Na+] Ambient Ambient "Water (50 mg/ml)

Ethanol (30 mg/ml)

DMSO (5 mg/ml)

DMF (5 mg/ml)" "Zhang ZH, Hao CL, Liu P, et al. Valproic acid inhibits tumor angiogenesis in mice transplanted with Kasumi 1 leukemia cells. Mol Med Rep. 2014 Feb;9(2):443-9. PMID: 24297248.

 

Ji MH, Li GM, Jia M, et al. Valproic acid attenuates lipopolysaccharide-induced acute lung injury in mice. Inflammation. 2013 Dec;36(6):1453-9. PMID: 23846716.

 

Zhao L, Chen CN, Hajji N, et al. Histone deacetylation inhibition in pulmonary hypertension: therapeutic potential of valproic acid and suberoylanilide hydroxamic acid. Circulation. 2012 Jul 24;126(4):455-67. PMID: 22711276.

 

Rosenberg G. The mechanisms of action of valproate in neuropsychiatric disorders: can we see the forest for the trees? Cell Mol Life Sci. 2007 Aug;64(16):2090-103. PMID: 17514356.

 

Kelly KM, Gross RA, Macdonald RL. Valproic acid selectively reduces the low-threshold (T) calcium current in rat nodose neurons. Neurosci Lett. 1990 Aug 14;116(1-2):233-8. PMID: 2175404.

" Xn, T, Xi, Repr. Not dangerous goods.

LKT C2468 β-Calcitonin Gene Related Peptide, human 1 mg 672.2 Endogenous calcitonin-family peptide, involved in vasodilation and pain transmission; RAMP1 and CGRP agonist. β−CGRP 98824-26-1 ≥98% 3793.38 C162H267N51O48S3 Ambient -20°C "Ma W, Zhang X, Shi S, et al. Neuropeptides stimulate human osteoblast activity and promote gap junctional intercellular communication. Neuropeptides. 2013 Jun;47(3):179-86. PMID: 23726661.

 

Yang JH, Zhang YQ, Guo Z. Endogenous CGRP protects retinal cells against stress induced apoptosis in rats. Neurosci Lett. 2011 Aug 26;501(2):83-5. PMID: 21763400.

 

Sink KS, Walker DL, Yang Y, et al. Calcitonin gene-related peptide in the bed nucleus of the stria terminalis produces an anxiety-like pattern of behavior and increases neural activation in anxiety-related structures. J Neurosci. 2011 Feb 2;31(5):1802-10. PMID: 21289190.

 

Mishima T, Ito Y, Hosono K, et al. Calcitonin gene-related peptide facilitates revascularization during hindlimb ischemia in mice. Am J Physiol Heart Circ Physiol. 2011 Feb;300(2):H431-9. PMID: 21131474.

 

Kroeger I, Erhardt A, Abt D, et al. The neuropeptide calcitonin gene-related peptide (CGRP) prevents inflammatory liver injury in mice. J Hepatol. 2009 Aug;51(2):342-53. PMID: 19464067.

" Xn Not dangerous goods.

LKT C2803 Chartreusin 5 mg 175 Binds DNA; RNA synthesis inhibitor. "Benzo(h)(1)benzopyrano(5,4,3-cde)(1)benzopyran-5,12-dione, 

10-((6-deoxy-2-O-(6-deoxy-3-O-methyl-alpha-D-

galactopyranosyl)-beta-D-galactopyranosyl)oxy)-6-hydroxy-1-

methyl- (9CI)" Lambdamycin; NSC-5159. 6377-18-0 ≥98% 640.6 C32H32O14 CC1C(C(C(C(O1)OC2=CC=CC3=C2C4=C5C6=C(C=CC(=C6C(=O)O4)C)OC(=O)C5=C3O)OC7C(C(C(C(O7)C)O)OC)O)O)O Protect from light. Store in a cool, dry place. Blue Ice -20°C Soluble in acetone. Practically insoluble in water. "Portugal J. Chartreusin, elsamicin A and related anti-cancer antibiotics. Curr Med Chem Anticancer Agents. 2003 Nov;3(6):411-20. PMID: 14529449.

 

Uramoto M, Kusano T, Nishio T, et al. Specific binding of chartreusin, an antitumor antibiotic, to DNA. FEBS Lett. 1983 Mar 21;153(2):325-8. PMID: 6311618.

 

Yagi M, Nishimura T, Suzuki H, et al. Chartreusin, an antitumor glycoside antibiotic, induces DNA strand scission. Biochem Biophys Res Commun. 1981 Feb 12;98(3):642-7. PMID: 7225117.

" Not dangerous goods.

LKT C2803 Chartreusin 25 mg 650 Binds DNA; RNA synthesis inhibitor. "Benzo(h)(1)benzopyrano(5,4,3-cde)(1)benzopyran-5,12-dione, 

10-((6-deoxy-2-O-(6-deoxy-3-O-methyl-alpha-D-

galactopyranosyl)-beta-D-galactopyranosyl)oxy)-6-hydroxy-1-

methyl- (9CI)" Lambdamycin; NSC-5159. 6377-18-0 ≥98% 640.6 C32H32O14 CC1C(C(C(C(O1)OC2=CC=CC3=C2C4=C5C6=C(C=CC(=C6C(=O)O4)C)OC(=O)C5=C3O)OC7C(C(C(C(O7)C)O)OC)O)O)O Protect from light. Store in a cool, dry place. Blue Ice -20°C Soluble in acetone. Practically insoluble in water. "Portugal J. Chartreusin, elsamicin A and related anti-cancer antibiotics. Curr Med Chem Anticancer Agents. 2003 Nov;3(6):411-20. PMID: 14529449.

 

Uramoto M, Kusano T, Nishio T, et al. Specific binding of chartreusin, an antitumor antibiotic, to DNA. FEBS Lett. 1983 Mar 21;153(2):325-8. PMID: 6311618.

 

Yagi M, Nishimura T, Suzuki H, et al. Chartreusin, an antitumor glycoside antibiotic, induces DNA strand scission. Biochem Biophys Res Commun. 1981 Feb 12;98(3):642-7. PMID: 7225117.

" Not dangerous goods.

LKT V0145 Valinomycin 5 mg 51.6 Peptide, neutral ionophore. Valinomicin 2001-95-8 ≥98% 1111.32 C54H90N6O18 CC1C(=O)NC(C(=O)OC(C(=O)NC(C(=O)OC(C(=O)NC(C(=O)OC(C(=O)NC(C(=O)OC(C(=O)NC(C(=O)OC(C(=O)NC(C(=O)O1)C(C)C)C(C)C)C(C)C)C)C(C)C)C(C)C)C(C)C)C)C(C)C)C(C)C)C(C)C Solutions can be stored up to 3 months. Ambient -20°C Insoluble in water. Soluble in ether, benzene, chloroform and acetone. "Li R, El-Mallahk RS. A novel evidence of different mechanisms of lithium and valproate neuroprotective action on human SY5Y neuroblastoma cells: caspase-3 dependency. Neurosci Lett. 2000 Nov 24;294(3):147-50. PMID: 11072136.

 

Gad SC, Reilly C, Siino K, et al. Thirteen cationic ionophores: their acute toxicity, neurobehavioral and membrane effects. Drug Chem Toxicol. 1985;8(6):451-68. PMID: 4092618.

 

Seshachalam D, Frahm DH, Ferraro FM. Cation reversal of inhibition of growth by valinomycin in Streptococcus pyogenes and Clostridium sporogenes. Antimicrob Agents Chemother. 1973 Jan;3(1):63-7. PMID: 4208280.

" Xn, T+ "UN number: 2811     Class: 6.1     Packing Group: I

Proper shipping name: Toxic solid, organic, n.o.s. (Valinomycin)"

LKT V0145 Valinomycin 10 mg 90.3 Peptide, neutral ionophore. Valinomicin 2001-95-8 ≥98% 1111.32 C54H90N6O18 CC1C(=O)NC(C(=O)OC(C(=O)NC(C(=O)OC(C(=O)NC(C(=O)OC(C(=O)NC(C(=O)OC(C(=O)NC(C(=O)OC(C(=O)NC(C(=O)O1)C(C)C)C(C)C)C(C)C)C)C(C)C)C(C)C)C(C)C)C)C(C)C)C(C)C)C(C)C Solutions can be stored up to 3 months. Ambient -20°C Insoluble in water. Soluble in ether, benzene, chloroform and acetone. "Li R, El-Mallahk RS. A novel evidence of different mechanisms of lithium and valproate neuroprotective action on human SY5Y neuroblastoma cells: caspase-3 dependency. Neurosci Lett. 2000 Nov 24;294(3):147-50. PMID: 11072136.

 

Gad SC, Reilly C, Siino K, et al. Thirteen cationic ionophores: their acute toxicity, neurobehavioral and membrane effects. Drug Chem Toxicol. 1985;8(6):451-68. PMID: 4092618.

 

Seshachalam D, Frahm DH, Ferraro FM. Cation reversal of inhibition of growth by valinomycin in Streptococcus pyogenes and Clostridium sporogenes. Antimicrob Agents Chemother. 1973 Jan;3(1):63-7. PMID: 4208280.

" Xn, T+ "UN number: 2811     Class: 6.1     Packing Group: I

Proper shipping name: Toxic solid, organic, n.o.s. (Valinomycin)"

LKT V0145 Valinomycin 25 mg 163.6 Peptide, neutral ionophore. Valinomicin 2001-95-8 ≥98% 1111.32 C54H90N6O18 CC1C(=O)NC(C(=O)OC(C(=O)NC(C(=O)OC(C(=O)NC(C(=O)OC(C(=O)NC(C(=O)OC(C(=O)NC(C(=O)OC(C(=O)NC(C(=O)O1)C(C)C)C(C)C)C(C)C)C)C(C)C)C(C)C)C(C)C)C)C(C)C)C(C)C)C(C)C Solutions can be stored up to 3 months. Ambient -20°C Insoluble in water. Soluble in ether, benzene, chloroform and acetone. "Li R, El-Mallahk RS. A novel evidence of different mechanisms of lithium and valproate neuroprotective action on human SY5Y neuroblastoma cells: caspase-3 dependency. Neurosci Lett. 2000 Nov 24;294(3):147-50. PMID: 11072136.

 

Gad SC, Reilly C, Siino K, et al. Thirteen cationic ionophores: their acute toxicity, neurobehavioral and membrane effects. Drug Chem Toxicol. 1985;8(6):451-68. PMID: 4092618.

 

Seshachalam D, Frahm DH, Ferraro FM. Cation reversal of inhibition of growth by valinomycin in Streptococcus pyogenes and Clostridium sporogenes. Antimicrob Agents Chemother. 1973 Jan;3(1):63-7. PMID: 4208280.

" Xn, T+ "UN number: 2811     Class: 6.1     Packing Group: I

Proper shipping name: Toxic solid, organic, n.o.s. (Valinomycin)"

LKT C2818 Chelerythrine Chloride 1 mg 66 benzophenanthridine alkaloid found in Chelidonium and Zanthoxylum; PKC and Na+/K+ ATPase inhibitor. 1,2-Dimethoxy-12-methyl[1,3]benzodioxolo[5,6-c]phenanthridinium Toddaline 3895-92-9 ≥98% 383.82 C21H18ClNO4 C[N+]1=C2C(=C3C=CC(=C(C3=C1)OC)OC)C=CC4=CC5=C(C=C42)OCO5.[Cl-] Ambient -20°C Soluble in DMSO. "Niu X, Mu Q, Li W, et al. Protective Effects of Chelerythrine Against Lipopolysaccharide-Induced Endotoxic Shock in Mice. Inflammation. 2014 Jun 14. [Epub ahead of print]. PMID: 24928629.

 

Dorney KM, Sizemore IE, Alqahtani T, et al. Surface-enhanced Raman spectroscopy (SERS) tracking of chelerythrine, a Na(+)/K(+) pump inhibitor, into cytosol and plasma membrane fractions of human lens epithelial cell cultures. Cell Physiol Biochem. 2013;32(7):146-56. PMID: 24429821.

 

Zhang ZF, Guo Y, Zhang JB, et al. Induction of apoptosis by chelerythrine chloride through mitochondrial pathway and Bcl-2 family proteins in human hepatoma SMMC-7721 cell. Arch Pharm Res. 2011 May;34(5):791-800. PMID: 21656365.

" Xn Not dangerous goods.

LKT C2818 Chelerythrine Chloride 5 mg 241.6 benzophenanthridine alkaloid found in Chelidonium and Zanthoxylum; PKC and Na+/K+ ATPase inhibitor. 1,2-Dimethoxy-12-methyl[1,3]benzodioxolo[5,6-c]phenanthridinium Toddaline 3895-92-9 ≥98% 383.82 C21H18ClNO4 C[N+]1=C2C(=C3C=CC(=C(C3=C1)OC)OC)C=CC4=CC5=C(C=C42)OCO5.[Cl-] Ambient -20°C Soluble in DMSO. "Niu X, Mu Q, Li W, et al. Protective Effects of Chelerythrine Against Lipopolysaccharide-Induced Endotoxic Shock in Mice. Inflammation. 2014 Jun 14. [Epub ahead of print]. PMID: 24928629.

 

Dorney KM, Sizemore IE, Alqahtani T, et al. Surface-enhanced Raman spectroscopy (SERS) tracking of chelerythrine, a Na(+)/K(+) pump inhibitor, into cytosol and plasma membrane fractions of human lens epithelial cell cultures. Cell Physiol Biochem. 2013;32(7):146-56. PMID: 24429821.

 

Zhang ZF, Guo Y, Zhang JB, et al. Induction of apoptosis by chelerythrine chloride through mitochondrial pathway and Bcl-2 family proteins in human hepatoma SMMC-7721 cell. Arch Pharm Res. 2011 May;34(5):791-800. PMID: 21656365.

" Xn Not dangerous goods.

LKT V0045 Valacyclovir Hydrochloride 50 mg 54.4 Neuraminidase inhibitor. L-Valine 2-[(2-amino-1,6-dihydro-6-oxo-9H-purin-9- yl)methoxy]ethyl ester hydrochloride Valacyclovir hydrochloride; BW-256U87 124832-27-5 ≥98% 360.8 C13H20N6O4 HCl CC(C)C(C(=O)OCCOCN1C=NC2=C1NC(=NC2=O)N)N.Cl Ambient Ambient Soluble in water. "Gupta D, Varghese Gupta S, Dahan A, et al. Increasing oral absorption of polar neuraminidase inhibitors: a prodrug transporter approach applied to oseltamivir analogue. Mol Pharm. 2013 Feb 4;10(2):512-22. PMID: 23244438.

 

Roxby AC, Liu AY, Drake AL, et al.  Short communication: T cell activation in HIV-1/herpes simplex virus-2-coinfected Kenyan women receiving valacyclovir. AIDS Res Hum Retroviruses. 2013 Jan;29(1):94-8. PMID: 22852760.

 

Andrei G, Snoeck R. Emerging drugs for varicella-zoster virus infections. Expert Opin Emerg Drugs. 2011 Sep;16(3):507-35. PMID: 21699441.

" Xi Not dangerous goods.

LKT V0045 Valacyclovir Hydrochloride 100 mg 101.9 Neuraminidase inhibitor. L-Valine 2-[(2-amino-1,6-dihydro-6-oxo-9H-purin-9- yl)methoxy]ethyl ester hydrochloride Valacyclovir hydrochloride; BW-256U87 124832-27-5 ≥98% 360.8 C13H20N6O4 HCl CC(C)C(C(=O)OCCOCN1C=NC2=C1NC(=NC2=O)N)N.Cl Ambient Ambient Soluble in water. "Gupta D, Varghese Gupta S, Dahan A, et al. Increasing oral absorption of polar neuraminidase inhibitors: a prodrug transporter approach applied to oseltamivir analogue. Mol Pharm. 2013 Feb 4;10(2):512-22. PMID: 23244438.

 

Roxby AC, Liu AY, Drake AL, et al.  Short communication: T cell activation in HIV-1/herpes simplex virus-2-coinfected Kenyan women receiving valacyclovir. AIDS Res Hum Retroviruses. 2013 Jan;29(1):94-8. PMID: 22852760.

 

Andrei G, Snoeck R. Emerging drugs for varicella-zoster virus infections. Expert Opin Emerg Drugs. 2011 Sep;16(3):507-35. PMID: 21699441.

" Xi Not dangerous goods.

LKT V0045 Valacyclovir Hydrochloride 500 mg 373.7 Neuraminidase inhibitor. L-Valine 2-[(2-amino-1,6-dihydro-6-oxo-9H-purin-9- yl)methoxy]ethyl ester hydrochloride Valacyclovir hydrochloride; BW-256U87 124832-27-5 ≥98% 360.8 C13H20N6O4 HCl CC(C)C(C(=O)OCCOCN1C=NC2=C1NC(=NC2=O)N)N.Cl Ambient Ambient Soluble in water. "Gupta D, Varghese Gupta S, Dahan A, et al. Increasing oral absorption of polar neuraminidase inhibitors: a prodrug transporter approach applied to oseltamivir analogue. Mol Pharm. 2013 Feb 4;10(2):512-22. PMID: 23244438.

 

Roxby AC, Liu AY, Drake AL, et al.  Short communication: T cell activation in HIV-1/herpes simplex virus-2-coinfected Kenyan women receiving valacyclovir. AIDS Res Hum Retroviruses. 2013 Jan;29(1):94-8. PMID: 22852760.

 

Andrei G, Snoeck R. Emerging drugs for varicella-zoster virus infections. Expert Opin Emerg Drugs. 2011 Sep;16(3):507-35. PMID: 21699441.

" Xi Not dangerous goods.

LKT U7354 Usnic Acid 5 g 56.7 Dibenzofuran produced by lichens. "2,6-Diacetyl-7,9-dihydroxy-8,9b-dimethyl-1,3(2H,9bh)-

dibenzofurandione 

" "Uanic acid; Usninic acid; Usnein

" 125-46-2 ≥98% 344.32 C18H16O7 CC1=C(C(=C2C(=C1O)C3(C(=CC(=O)C(C3=O)C(=O)C)O2)C)C(=O)C)O Ambient Ambient Soluble water (1.1 mg/mL), acetone (7.7 mg/mL), ethyl acetate (0.88 mg/mL) or ethanol. "Singh N, Nambiar D, Kale RK, et al. Usnic acid inhibits growth and induces cell cycle arrest and apoptosis in human lung carcinoma A549 cells. Nutr Cancer. 2013;65 Suppl 1:36-43. PMID: 23682781.

 

Song Y, Dai F, Zhai D, et al. Usnic acid inhibits breast tumor angiogenesis and growth by suppressing VEGFR2-mediated AKT and ERK1/2 signaling pathways. Angiogenesis. 2012 Sep;15(3):421-32. PMID: 22669534.

 

Ramos DF, Almeida da Silva PE. Antimycobacterial activity of usnic acid against resistant and susceptible strains of Mycobacterium tuberculosis and non-tuberculous mycobacteria. Pharm Biol. 2010 Mar;48(3):260-3. PMID: 20645810.

" Not dangerous goods.

LKT U7354 Usnic Acid 25 g 206 Dibenzofuran produced by lichens. "2,6-Diacetyl-7,9-dihydroxy-8,9b-dimethyl-1,3(2H,9bh)-

dibenzofurandione 

" "Uanic acid; Usninic acid; Usnein

" 125-46-2 ≥98% 344.32 C18H16O7 CC1=C(C(=C2C(=C1O)C3(C(=CC(=O)C(C3=O)C(=O)C)O2)C)C(=O)C)O Ambient Ambient Soluble water (1.1 mg/mL), acetone (7.7 mg/mL), ethyl acetate (0.88 mg/mL) or ethanol. "Singh N, Nambiar D, Kale RK, et al. Usnic acid inhibits growth and induces cell cycle arrest and apoptosis in human lung carcinoma A549 cells. Nutr Cancer. 2013;65 Suppl 1:36-43. PMID: 23682781.

 

Song Y, Dai F, Zhai D, et al. Usnic acid inhibits breast tumor angiogenesis and growth by suppressing VEGFR2-mediated AKT and ERK1/2 signaling pathways. Angiogenesis. 2012 Sep;15(3):421-32. PMID: 22669534.

 

Ramos DF, Almeida da Silva PE. Antimycobacterial activity of usnic acid against resistant and susceptible strains of Mycobacterium tuberculosis and non-tuberculous mycobacteria. Pharm Biol. 2010 Mar;48(3):260-3. PMID: 20645810.

" Not dangerous goods.

LKT U6959 Urotensin II, human 0.5 mg 204.1 Endogenous peptide, involved in stress signaling; UT agonist. ≥95% 1388.6 C64H85N13O18S2 Ambient -20°C "Peng H, Zhang M, Cai X, et al. Association between Human Urotensin II and Essential Hypertension-A 1:1 Matched Case-Control Study. PLoS One. 2013 Dec 10;8(12):e81764. PMID: 24339964.

 

Wang HX, Wu XR, Yang H, et al. Urotensin II inhibits skeletal muscle glucose transport signaling pathways via the NADPH oxidase pathway. PLoS One. 2013 Oct 8;8(10):e76796. PMID: 24116164.

 

Park SL, Lee BK, Kim YA, et al. Inhibitory Effect of an Urotensin II Receptor Antagonist on Proinflammatory Activation Induced by Urotensin II in Human Vascular Endothelial Cells. Biomol Ther (Seoul). 2013 Jul 30;21(4):277-83. PMID: 24244812.

" Not dangerous goods.

LKT U6959 Urotensin II, human 1 mg 348 Endogenous peptide, involved in stress signaling; UT agonist. ≥95% 1388.6 C64H85N13O18S2 Ambient -20°C "Peng H, Zhang M, Cai X, et al. Association between Human Urotensin II and Essential Hypertension-A 1:1 Matched Case-Control Study. PLoS One. 2013 Dec 10;8(12):e81764. PMID: 24339964.

 

Wang HX, Wu XR, Yang H, et al. Urotensin II inhibits skeletal muscle glucose transport signaling pathways via the NADPH oxidase pathway. PLoS One. 2013 Oct 8;8(10):e76796. PMID: 24116164.

 

Park SL, Lee BK, Kim YA, et al. Inhibitory Effect of an Urotensin II Receptor Antagonist on Proinflammatory Activation Induced by Urotensin II in Human Vascular Endothelial Cells. Biomol Ther (Seoul). 2013 Jul 30;21(4):277-83. PMID: 24244812.

" Not dangerous goods.

LKT U6958 Urotensin II, frog 0.5 mg 204.1 Endogenous peptide, involved in stress signaling; UT agonist. ≥95% 1517.76 C69H96N16O19S2 Ambient -20°C "Peng H, Zhang M, Cai X, et al. Association between Human Urotensin II and Essential Hypertension-A 1:1 Matched Case-Control Study. PLoS One. 2013 Dec 10;8(12):e81764. PMID: 24339964.

 

Wang HX, Wu XR, Yang H, et al. Urotensin II inhibits skeletal muscle glucose transport signaling pathways via the NADPH oxidase pathway. PLoS One. 2013 Oct 8;8(10):e76796. PMID: 24116164.

 

Park SL, Lee BK, Kim YA, et al. Inhibitory Effect of an Urotensin II Receptor Antagonist on Proinflammatory Activation Induced by Urotensin II in Human Vascular Endothelial Cells. Biomol Ther (Seoul). 2013 Jul 30;21(4):277-83. PMID: 24244812.

" Not dangerous goods.

LKT U6958 Urotensin II, frog 1 mg 348 Endogenous peptide, involved in stress signaling; UT agonist. ≥95% 1517.76 C69H96N16O19S2 Ambient -20°C "Peng H, Zhang M, Cai X, et al. Association between Human Urotensin II and Essential Hypertension-A 1:1 Matched Case-Control Study. PLoS One. 2013 Dec 10;8(12):e81764. PMID: 24339964.

 

Wang HX, Wu XR, Yang H, et al. Urotensin II inhibits skeletal muscle glucose transport signaling pathways via the NADPH oxidase pathway. PLoS One. 2013 Oct 8;8(10):e76796. PMID: 24116164.

 

Park SL, Lee BK, Kim YA, et al. Inhibitory Effect of an Urotensin II Receptor Antagonist on Proinflammatory Activation Induced by Urotensin II in Human Vascular Endothelial Cells. Biomol Ther (Seoul). 2013 Jul 30;21(4):277-83. PMID: 24244812.

" Not dangerous goods.

LKT U6958 Urotensin II, frog 2.5 mg 612.4 Endogenous peptide, involved in stress signaling; UT agonist. ≥95% 1517.76 C69H96N16O19S2 Ambient -20°C "Peng H, Zhang M, Cai X, et al. Association between Human Urotensin II and Essential Hypertension-A 1:1 Matched Case-Control Study. PLoS One. 2013 Dec 10;8(12):e81764. PMID: 24339964.

 

Wang HX, Wu XR, Yang H, et al. Urotensin II inhibits skeletal muscle glucose transport signaling pathways via the NADPH oxidase pathway. PLoS One. 2013 Oct 8;8(10):e76796. PMID: 24116164.

 

Park SL, Lee BK, Kim YA, et al. Inhibitory Effect of an Urotensin II Receptor Antagonist on Proinflammatory Activation Induced by Urotensin II in Human Vascular Endothelial Cells. Biomol Ther (Seoul). 2013 Jul 30;21(4):277-83. PMID: 24244812.

" Not dangerous goods.

LKT U6957 Urotensin I 0.5 mg 345.1 Endogenous peptide, involved in stress signaling; CRF1/2 agonist. ≥95% 4869.55 C210H340N62O67S2 Ambient -20°C "Ortega VA, Lovejoy DA, Bernier NJ. Appetite-suppressing effects and interactions of centrally administered corticotropin-releasing factor, urotensin I and serotonin in rainbow trout (Oncorhynchus mykiss). Front Neurosci. 2013 Oct 29;7:196. PMID: 24194695.

 

Backström T, Pettersson A, Johansson V, et al. CRF and urotensin I effects on aggression and anxiety-like behavior in rainbow trout. J Exp Biol. 2011 Mar 15;214(Pt 6):907-14. PMID: 21346117.

 

Boorse GC, Denver RJ. Widespread tissue distribution and diverse functions of corticotropin-releasing factor and related peptides. Gen Comp Endocrinol. 2006 Mar;146(1):9-18. PMID: 16413023.

" Not dangerous goods.

LKT U6957 Urotensin I 1 mg 587.9 Endogenous peptide, involved in stress signaling; CRF1/2 agonist. ≥95% 4869.55 C210H340N62O67S2 Ambient -20°C "Ortega VA, Lovejoy DA, Bernier NJ. Appetite-suppressing effects and interactions of centrally administered corticotropin-releasing factor, urotensin I and serotonin in rainbow trout (Oncorhynchus mykiss). Front Neurosci. 2013 Oct 29;7:196. PMID: 24194695.

 

Backström T, Pettersson A, Johansson V, et al. CRF and urotensin I effects on aggression and anxiety-like behavior in rainbow trout. J Exp Biol. 2011 Mar 15;214(Pt 6):907-14. PMID: 21346117.

 

Boorse GC, Denver RJ. Widespread tissue distribution and diverse functions of corticotropin-releasing factor and related peptides. Gen Comp Endocrinol. 2006 Mar;146(1):9-18. PMID: 16413023.

" Not dangerous goods.

LKT U6957 Urotensin I 2.5 mg 1038 Endogenous peptide, involved in stress signaling; CRF1/2 agonist. ≥95% 4869.55 C210H340N62O67S2 Ambient -20°C "Ortega VA, Lovejoy DA, Bernier NJ. Appetite-suppressing effects and interactions of centrally administered corticotropin-releasing factor, urotensin I and serotonin in rainbow trout (Oncorhynchus mykiss). Front Neurosci. 2013 Oct 29;7:196. PMID: 24194695.

 

Backström T, Pettersson A, Johansson V, et al. CRF and urotensin I effects on aggression and anxiety-like behavior in rainbow trout. J Exp Biol. 2011 Mar 15;214(Pt 6):907-14. PMID: 21346117.

 

Boorse GC, Denver RJ. Widespread tissue distribution and diverse functions of corticotropin-releasing factor and related peptides. Gen Comp Endocrinol. 2006 Mar;146(1):9-18. PMID: 16413023.

" Not dangerous goods.

LKT U6956 Uroguanylin, human 0.5 mg 228 Endogenous peptide, involved in water/Na+ homeostasis; GC-C agonist. ≥95% 1667.89 C64H102N18O26S4 Ambient -20°C "Teixeira MD, Nascimento NR, Fonteles MC, et al. Uroguanylin induces electroencephalographic spikes in rats. Braz J Biol. 2013 Aug;73(3):623-7. PMID: 24212704.

 

Lessa LM, Carraro-Lacroix LR, Crajoinas RO, et al. Mechanisms underlying the inhibitory effects of uroguanylin on NHE3 transport activity in renal proximal tubule. Am J Physiol Renal Physiol. 2012 Nov 15;303(10):F1399-408. PMID: 22952280.

 

Toriano R, Ozu M, Politi MT, et al. Uroguanylin regulates net fluid secretion via the NHE2 isoform of the Na/H+ exchanger in an intestinal cellular model. Cell Physiol Biochem. 2011;28(4):733-42. PMID: 22178885.

" Not dangerous goods.

LKT U6956 Uroguanylin, human 1 mg 387 Endogenous peptide, involved in water/Na+ homeostasis; GC-C agonist. ≥95% 1667.89 C64H102N18O26S4 Ambient -20°C "Teixeira MD, Nascimento NR, Fonteles MC, et al. Uroguanylin induces electroencephalographic spikes in rats. Braz J Biol. 2013 Aug;73(3):623-7. PMID: 24212704.

 

Lessa LM, Carraro-Lacroix LR, Crajoinas RO, et al. Mechanisms underlying the inhibitory effects of uroguanylin on NHE3 transport activity in renal proximal tubule. Am J Physiol Renal Physiol. 2012 Nov 15;303(10):F1399-408. PMID: 22952280.

 

Toriano R, Ozu M, Politi MT, et al. Uroguanylin regulates net fluid secretion via the NHE2 isoform of the Na/H+ exchanger in an intestinal cellular model. Cell Physiol Biochem. 2011;28(4):733-42. PMID: 22178885.

" Not dangerous goods.

LKT U6956 Uroguanylin, human 2.5 mg 684.1 Endogenous peptide, involved in water/Na+ homeostasis; GC-C agonist. ≥95% 1667.89 C64H102N18O26S4 Ambient -20°C "Teixeira MD, Nascimento NR, Fonteles MC, et al. Uroguanylin induces electroencephalographic spikes in rats. Braz J Biol. 2013 Aug;73(3):623-7. PMID: 24212704.

 

Lessa LM, Carraro-Lacroix LR, Crajoinas RO, et al. Mechanisms underlying the inhibitory effects of uroguanylin on NHE3 transport activity in renal proximal tubule. Am J Physiol Renal Physiol. 2012 Nov 15;303(10):F1399-408. PMID: 22952280.

 

Toriano R, Ozu M, Politi MT, et al. Uroguanylin regulates net fluid secretion via the NHE2 isoform of the Na/H+ exchanger in an intestinal cellular model. Cell Physiol Biochem. 2011;28(4):733-42. PMID: 22178885.

" Not dangerous goods.

LKT U6901 Uracil 10 g 26.8 Endogenous pyrimidine base required for production of RNA, used in synthesis of caffeine. 2,4(1H,3H)-Pyrimidinedione 2,4-Dihydroxypyrimidine; 2,4-Pyrimidinediol 66-22-8 ≥98% 112.09 C4H4N2O2 C1=CNC(=O)NC1=O Ambient Ambient Soluble in hot water. Insoluble in alcohol or ether. soluble in ammonia water and other alkalies (pH 9.5). "Matyugina E, Khandazhinskaya A, Chernousova L, et al. The synthesis and antituberculosis activity of 5'-nor carbocyclic uracil derivatives. Bioorg Med Chem. 2012 Nov 15;20(22):6680-6. PMID: 23062712.

 

Parker JB, Stivers JT. Dynamics of uracil and 5-fluorouracil in DNA. Biochemistry. 2011 Feb 8;50(5):612-7. PMID: 21190322.

" Not dangerous goods.

LKT U6901 Uracil 25 g 40.6 Endogenous pyrimidine base required for production of RNA, used in synthesis of caffeine. 2,4(1H,3H)-Pyrimidinedione 2,4-Dihydroxypyrimidine; 2,4-Pyrimidinediol 66-22-8 ≥98% 112.09 C4H4N2O2 C1=CNC(=O)NC1=O Ambient Ambient Soluble in hot water. Insoluble in alcohol or ether. soluble in ammonia water and other alkalies (pH 9.5). "Matyugina E, Khandazhinskaya A, Chernousova L, et al. The synthesis and antituberculosis activity of 5'-nor carbocyclic uracil derivatives. Bioorg Med Chem. 2012 Nov 15;20(22):6680-6. PMID: 23062712.

 

Parker JB, Stivers JT. Dynamics of uracil and 5-fluorouracil in DNA. Biochemistry. 2011 Feb 8;50(5):612-7. PMID: 21190322.

" Not dangerous goods.

LKT U6901 Uracil 100 g 67.5 Endogenous pyrimidine base required for production of RNA, used in synthesis of caffeine. 2,4(1H,3H)-Pyrimidinedione 2,4-Dihydroxypyrimidine; 2,4-Pyrimidinediol 66-22-8 ≥98% 112.09 C4H4N2O2 C1=CNC(=O)NC1=O Ambient Ambient Soluble in hot water. Insoluble in alcohol or ether. soluble in ammonia water and other alkalies (pH 9.5). "Matyugina E, Khandazhinskaya A, Chernousova L, et al. The synthesis and antituberculosis activity of 5'-nor carbocyclic uracil derivatives. Bioorg Med Chem. 2012 Nov 15;20(22):6680-6. PMID: 23062712.

 

Parker JB, Stivers JT. Dynamics of uracil and 5-fluorouracil in DNA. Biochemistry. 2011 Feb 8;50(5):612-7. PMID: 21190322.

" Not dangerous goods.

LKT U6873 Ursodeoxycholic Acid 1 g 64.2 Endogenous secondary bile acid. (3α,5β,7β)-3,7-Dihydroxycholan-24-oic acid Ursodiol; Actigall; Delursan; Desol; Litursol; Peptarom; Urdes; Ursofalk; Ursolvan 128-13-2 ≥98% 392.57 C24H40O4 CC(CCC(=O)O)C1CCC2C1(CCC3C2C(CC4C3(CCC(C4)O)C)O)C Ambient Ambient Insoluble in water. Soluble in ethanol. Slightly soluble  in chloroform. "Zhang Q, Nakaki T, Iwami D, et al. Induction of regulatory T cells and indefinite survival of fully allogeneic cardiac grafts by ursodeoxycholic acid in mice. Transplantation. 2009 Dec 27;88(12):1360-70. PMID: 20029332.

 

El-Sherbiny GA, Taye A, Abdel-Raheem IT. Role of ursodeoxycholic acid in prevention of hepatotoxicity caused by amoxicillin-clavulanic acid in rats. Ann Hepatol. 2009 Apr-Jun;8(2):134-40. PMID: 19502657.

 

Akare S, Jean-Louis S, Chen W, et al. Ursodeoxycholic acid modulates histone acetylation and induces differentiation and senescence. Int J Cancer. 2006 Dec 15;119(12):2958-69. PMID: 17019713.

 

Colecchia A, Mazzella G, Sandri L, et al. Ursodeoxycholic acid improves gastrointestinal motility defects in gallstone patients. World J Gastroenterol. 2006 Sep 7;12(33):5336-43. PMID: 16981264.

" Xi Not dangerous goods.

LKT U6873 Ursodeoxycholic Acid 5 g 203.7 Endogenous secondary bile acid. (3α,5β,7β)-3,7-Dihydroxycholan-24-oic acid Ursodiol; Actigall; Delursan; Desol; Litursol; Peptarom; Urdes; Ursofalk; Ursolvan 128-13-2 ≥98% 392.57 C24H40O4 CC(CCC(=O)O)C1CCC2C1(CCC3C2C(CC4C3(CCC(C4)O)C)O)C Ambient Ambient Insoluble in water. Soluble in ethanol. Slightly soluble  in chloroform. "Zhang Q, Nakaki T, Iwami D, et al. Induction of regulatory T cells and indefinite survival of fully allogeneic cardiac grafts by ursodeoxycholic acid in mice. Transplantation. 2009 Dec 27;88(12):1360-70. PMID: 20029332.

 

El-Sherbiny GA, Taye A, Abdel-Raheem IT. Role of ursodeoxycholic acid in prevention of hepatotoxicity caused by amoxicillin-clavulanic acid in rats. Ann Hepatol. 2009 Apr-Jun;8(2):134-40. PMID: 19502657.

 

Akare S, Jean-Louis S, Chen W, et al. Ursodeoxycholic acid modulates histone acetylation and induces differentiation and senescence. Int J Cancer. 2006 Dec 15;119(12):2958-69. PMID: 17019713.

 

Colecchia A, Mazzella G, Sandri L, et al. Ursodeoxycholic acid improves gastrointestinal motility defects in gallstone patients. World J Gastroenterol. 2006 Sep 7;12(33):5336-43. PMID: 16981264.

" Xi Not dangerous goods.

LKT U6860 Urocortin III, mouse 0.5 mg 420.1 Endogenous peptide, involved in stress signaling; CRF2 agonist. ≥95% 4173.01 C186H312N52O52S2 Ambient -20°C "Bagosi Z, Csabafi K, Palotai M, et al. The interaction of Urocortin II and Urocortin III with amygdalar and hypothalamic cotricotropin-releasing factor (CRF)--reflections on the regulation of the hypothalamic-pituitary-adrenal (HPA) axis. Neuropeptides. 2013 Oct;47(5):333-8. PMID: 23932308.

 

Takahashi K, Totsune K, Murakami O, et al. Urocortins as cardiovascular peptides. Peptides. 2004 Oct;25(10):1723-31. PMID: 15476939.

 

Suda T, Kageyama K, Sakihara S, et al. Physiological roles of urocortins, human homologues of fish urotensin I, and their receptors. Peptides. 2004 Oct;25(10):1689-701. PMID: 15476936.

" Not dangerous goods.

LKT U6860 Urocortin III, mouse 1 mg 714.2 Endogenous peptide, involved in stress signaling; CRF2 agonist. ≥95% 4173.01 C186H312N52O52S2 Ambient -20°C "Bagosi Z, Csabafi K, Palotai M, et al. The interaction of Urocortin II and Urocortin III with amygdalar and hypothalamic cotricotropin-releasing factor (CRF)--reflections on the regulation of the hypothalamic-pituitary-adrenal (HPA) axis. Neuropeptides. 2013 Oct;47(5):333-8. PMID: 23932308.

 

Takahashi K, Totsune K, Murakami O, et al. Urocortins as cardiovascular peptides. Peptides. 2004 Oct;25(10):1723-31. PMID: 15476939.

 

Suda T, Kageyama K, Sakihara S, et al. Physiological roles of urocortins, human homologues of fish urotensin I, and their receptors. Peptides. 2004 Oct;25(10):1689-701. PMID: 15476936.

" Not dangerous goods.

LKT U6860 Urocortin III, mouse 2.5 mg 1260.1 Endogenous peptide, involved in stress signaling; CRF2 agonist. ≥95% 4173.01 C186H312N52O52S2 Ambient -20°C "Bagosi Z, Csabafi K, Palotai M, et al. The interaction of Urocortin II and Urocortin III with amygdalar and hypothalamic cotricotropin-releasing factor (CRF)--reflections on the regulation of the hypothalamic-pituitary-adrenal (HPA) axis. Neuropeptides. 2013 Oct;47(5):333-8. PMID: 23932308.

 

Takahashi K, Totsune K, Murakami O, et al. Urocortins as cardiovascular peptides. Peptides. 2004 Oct;25(10):1723-31. PMID: 15476939.

 

Suda T, Kageyama K, Sakihara S, et al. Physiological roles of urocortins, human homologues of fish urotensin I, and their receptors. Peptides. 2004 Oct;25(10):1689-701. PMID: 15476936.

" Not dangerous goods.

LKT U6859 Urocortin III, human 0.5 mg 420.1 Endogenous peptide, involved in stress signaling; CRF2 agonist. ≥95% 4137.96 C185H307N53O50S2 CCC(C)C(C(=O)N)NC(=O)C(CCC(=O)N)NC(=O)C(C)NC(=O)C(CCSC)NC(=O)C(CC(C)C)NC(=O)C(CC1=CN=CN1)NC(=O)C(C)NC(=O)C(CC(=O)N)NC(=O)C(C)NC(=O)C(C)NC(=O)C(C)NC(=O)C(CCC(=O)N)NC(=O)C(C)NC(=O)C(CCCNC(=N)N)NC(=O)C(CC(C)C)NC(=O)C(CC(=O)N)NC(=O)C(CCCCN)NC(=O)C(C)NC(=O)C(CCCCN)NC(=O)C(C)NC(=O)C(C(C)CC)NC(=O)C(CC(=O)N)NC(=O)C(CC2=CC=CC=C2)NC(=O)C(CC(C)C)NC(=O)C(CC(C)C)NC(=O)C(CC(=O)N)NC(=O)C(CCSC)NC(=O)C(C(C)CC)NC(=O)C(CC(=O)N)NC(=O)C(C(C)O)NC(=O)C3CCCN3C(=O)C(C(C)C)NC(=O)C(CC(=O)O)NC(=O)C(CC(C)C)NC(=O)C(CO)NC(=O)C(CC(C)C)NC(=O)C(C(C)O)NC(=O)C(CC4=CC=CC=C4)N Ambient -20°C "Bagosi Z, Csabafi K, Palotai M, et al. The interaction of Urocortin II and Urocortin III with amygdalar and hypothalamic cotricotropin-releasing factor (CRF)--reflections on the regulation of the hypothalamic-pituitary-adrenal (HPA) axis. Neuropeptides. 2013 Oct;47(5):333-8. PMID: 23932308.

 

Takahashi K, Totsune K, Murakami O, et al. Urocortins as cardiovascular peptides. Peptides. 2004 Oct;25(10):1723-31. PMID: 15476939.

 

Suda T, Kageyama K, Sakihara S, et al. Physiological roles of urocortins, human homologues of fish urotensin I, and their receptors. Peptides. 2004 Oct;25(10):1689-701. PMID: 15476936.

" Not dangerous goods.

LKT U6859 Urocortin III, human 1 mg 714.2 Endogenous peptide, involved in stress signaling; CRF2 agonist. ≥95% 4137.96 C185H307N53O50S2 CCC(C)C(C(=O)N)NC(=O)C(CCC(=O)N)NC(=O)C(C)NC(=O)C(CCSC)NC(=O)C(CC(C)C)NC(=O)C(CC1=CN=CN1)NC(=O)C(C)NC(=O)C(CC(=O)N)NC(=O)C(C)NC(=O)C(C)NC(=O)C(C)NC(=O)C(CCC(=O)N)NC(=O)C(C)NC(=O)C(CCCNC(=N)N)NC(=O)C(CC(C)C)NC(=O)C(CC(=O)N)NC(=O)C(CCCCN)NC(=O)C(C)NC(=O)C(CCCCN)NC(=O)C(C)NC(=O)C(C(C)CC)NC(=O)C(CC(=O)N)NC(=O)C(CC2=CC=CC=C2)NC(=O)C(CC(C)C)NC(=O)C(CC(C)C)NC(=O)C(CC(=O)N)NC(=O)C(CCSC)NC(=O)C(C(C)CC)NC(=O)C(CC(=O)N)NC(=O)C(C(C)O)NC(=O)C3CCCN3C(=O)C(C(C)C)NC(=O)C(CC(=O)O)NC(=O)C(CC(C)C)NC(=O)C(CO)NC(=O)C(CC(C)C)NC(=O)C(C(C)O)NC(=O)C(CC4=CC=CC=C4)N Ambient -20°C "Bagosi Z, Csabafi K, Palotai M, et al. The interaction of Urocortin II and Urocortin III with amygdalar and hypothalamic cotricotropin-releasing factor (CRF)--reflections on the regulation of the hypothalamic-pituitary-adrenal (HPA) axis. Neuropeptides. 2013 Oct;47(5):333-8. PMID: 23932308.

 

Takahashi K, Totsune K, Murakami O, et al. Urocortins as cardiovascular peptides. Peptides. 2004 Oct;25(10):1723-31. PMID: 15476939.

 

Suda T, Kageyama K, Sakihara S, et al. Physiological roles of urocortins, human homologues of fish urotensin I, and their receptors. Peptides. 2004 Oct;25(10):1689-701. PMID: 15476936.

" Not dangerous goods.

LKT U6859 Urocortin III, human 2.5 mg 1260.1 Endogenous peptide, involved in stress signaling; CRF2 agonist. ≥95% 4137.96 C185H307N53O50S2 CCC(C)C(C(=O)N)NC(=O)C(CCC(=O)N)NC(=O)C(C)NC(=O)C(CCSC)NC(=O)C(CC(C)C)NC(=O)C(CC1=CN=CN1)NC(=O)C(C)NC(=O)C(CC(=O)N)NC(=O)C(C)NC(=O)C(C)NC(=O)C(C)NC(=O)C(CCC(=O)N)NC(=O)C(C)NC(=O)C(CCCNC(=N)N)NC(=O)C(CC(C)C)NC(=O)C(CC(=O)N)NC(=O)C(CCCCN)NC(=O)C(C)NC(=O)C(CCCCN)NC(=O)C(C)NC(=O)C(C(C)CC)NC(=O)C(CC(=O)N)NC(=O)C(CC2=CC=CC=C2)NC(=O)C(CC(C)C)NC(=O)C(CC(C)C)NC(=O)C(CC(=O)N)NC(=O)C(CCSC)NC(=O)C(C(C)CC)NC(=O)C(CC(=O)N)NC(=O)C(C(C)O)NC(=O)C3CCCN3C(=O)C(C(C)C)NC(=O)C(CC(=O)O)NC(=O)C(CC(C)C)NC(=O)C(CO)NC(=O)C(CC(C)C)NC(=O)C(C(C)O)NC(=O)C(CC4=CC=CC=C4)N Ambient -20°C "Bagosi Z, Csabafi K, Palotai M, et al. The interaction of Urocortin II and Urocortin III with amygdalar and hypothalamic cotricotropin-releasing factor (CRF)--reflections on the regulation of the hypothalamic-pituitary-adrenal (HPA) axis. Neuropeptides. 2013 Oct;47(5):333-8. PMID: 23932308.

 

Takahashi K, Totsune K, Murakami O, et al. Urocortins as cardiovascular peptides. Peptides. 2004 Oct;25(10):1723-31. PMID: 15476939.

 

Suda T, Kageyama K, Sakihara S, et al. Physiological roles of urocortins, human homologues of fish urotensin I, and their receptors. Peptides. 2004 Oct;25(10):1689-701. PMID: 15476936.

" Not dangerous goods.

LKT U6858 Urocortin II, mouse 0.5 mg 420.1 Endogenous peptide, involved in stress signaling; CRF2 agonist. ≥95% 4152.98 C187H320N56O50 Ambient -20°C "Campos-Salinas J, Caro M, Cavazzuti A, et al. Protective Role of the Neuropeptide Urocortin II against Experimental Sepsis and Leishmaniasis by Direct Killing of Pathogens. J Immunol. 2013 Dec 15;191(12):6040-51. PMID: 24249730.

 

Grossini E, Caimmi PP, Molinari C, et al. Modulation of calcium movements by urocortin II in endothelial cells. Cell Physiol Biochem. 2010;25(2-3):221-32. PMID: 20110683.

 

Grossini E, Molinari C, Mary DA, et al. The effect of urocortin II administration on the coronary circulation and cardiac function in the anaesthetized pig is nitric-oxide-dependent. Eur J Pharmacol. 2008 Jan 14;578(2-3):242-8. PMID: 17936748.

 

Takahashi K, Totsune K, Murakami O, et al. Urocortins as cardiovascular peptides. Peptides. 2004 Oct;25(10):1723-31. PMID: 15476939.

 

Suda T, Kageyama K, Sakihara S, et al. Physiological roles of urocortins, human homologues of fish urotensin I, and their receptors. Peptides. 2004 Oct;25(10):1689-701. PMID: 15476936.

" Not dangerous goods.

LKT U6858 Urocortin II, mouse 1 mg 714.2 Endogenous peptide, involved in stress signaling; CRF2 agonist. ≥95% 4152.98 C187H320N56O50 Ambient -20°C "Campos-Salinas J, Caro M, Cavazzuti A, et al. Protective Role of the Neuropeptide Urocortin II against Experimental Sepsis and Leishmaniasis by Direct Killing of Pathogens. J Immunol. 2013 Dec 15;191(12):6040-51. PMID: 24249730.

 

Grossini E, Caimmi PP, Molinari C, et al. Modulation of calcium movements by urocortin II in endothelial cells. Cell Physiol Biochem. 2010;25(2-3):221-32. PMID: 20110683.

 

Grossini E, Molinari C, Mary DA, et al. The effect of urocortin II administration on the coronary circulation and cardiac function in the anaesthetized pig is nitric-oxide-dependent. Eur J Pharmacol. 2008 Jan 14;578(2-3):242-8. PMID: 17936748.

 

Takahashi K, Totsune K, Murakami O, et al. Urocortins as cardiovascular peptides. Peptides. 2004 Oct;25(10):1723-31. PMID: 15476939.

 

Suda T, Kageyama K, Sakihara S, et al. Physiological roles of urocortins, human homologues of fish urotensin I, and their receptors. Peptides. 2004 Oct;25(10):1689-701. PMID: 15476936.

" Not dangerous goods.

LKT U6858 Urocortin II, mouse 2.5 mg 1260.1 Endogenous peptide, involved in stress signaling; CRF2 agonist. ≥95% 4152.98 C187H320N56O50 Ambient -20°C "Campos-Salinas J, Caro M, Cavazzuti A, et al. Protective Role of the Neuropeptide Urocortin II against Experimental Sepsis and Leishmaniasis by Direct Killing of Pathogens. J Immunol. 2013 Dec 15;191(12):6040-51. PMID: 24249730.

 

Grossini E, Caimmi PP, Molinari C, et al. Modulation of calcium movements by urocortin II in endothelial cells. Cell Physiol Biochem. 2010;25(2-3):221-32. PMID: 20110683.

 

Grossini E, Molinari C, Mary DA, et al. The effect of urocortin II administration on the coronary circulation and cardiac function in the anaesthetized pig is nitric-oxide-dependent. Eur J Pharmacol. 2008 Jan 14;578(2-3):242-8. PMID: 17936748.

 

Takahashi K, Totsune K, Murakami O, et al. Urocortins as cardiovascular peptides. Peptides. 2004 Oct;25(10):1723-31. PMID: 15476939.

 

Suda T, Kageyama K, Sakihara S, et al. Physiological roles of urocortins, human homologues of fish urotensin I, and their receptors. Peptides. 2004 Oct;25(10):1689-701. PMID: 15476936.

" Not dangerous goods.

LKT U6857 Urodilatin CCC 1 mg 540 ANP fragment, natriuretic peptide; Na+/K+ ATPase inhibitor. Ularitide; Atriopeptin; Anp; Anf; ANP (95-129); A-type natriuretic peptide; Atrial natriuretic peptide 115966-23-9 ≥98% 3506 C145H234N52O44S3 CCC(C)C1C(=O)NCC(=O)NC(C(=O)NC(C(=O)NC(C(=O)NCC(=O)NC(C(=O)NCC(=O)NC(CSSCC(C(=O)NC(C(=O)NCC(=O)NCC(=O)NC(C(=O)NC(C(=O)NC(C(=O)NC(C(=O)N1)CCCNC(=N)N)CC(=O)O)CCSC)CCCNC(=N)N)CC2=CC=CC=C2)NC(=O)C(CO)NC(=O)C(CO)NC(=O)C(CCCNC(=N)N)NC(=O)C(CCCNC(=N)N)NC(=O)C(CC(C)C)NC(=O)C(CO)NC(=O)C(CCCNC(=N)N)NC(=O)C3CCCN3C(=O)C(C)NC(=O)C(C(C)O)N)C(=O)NC(CC(=O)N)C(=O)NC(CO)C(=O)NC(CC4=CC=CC=C4)C(=O)NC(CCCNC(=N)N)C(=O)NC(CC5=CC=C(C=C5)O)C(=O)O)CC(C)C)CO)CCC(=O)N)C Ambient -20°C "Choi MR, Citarella MR, Lee BM, et al. Urodilatin regulates renal dopamine metabolism. J Nephrol. 2013 Nov-Dec;26(6):1042-8. PMID: 23661592.

 

Vives D, Farage S, Motta R, et al. Atrial natriuretic peptides and urodilatin modulate proximal tubule Na(+)-ATPase activity through activation of the NPR-A/cGMP/PKG pathway. Peptides. 2010 May;31(5):903-8. PMID: 20206222.

"

LKT U6856 Urocortin II, human 0.5 mg 420.1 Endogenous peptide, involved in stress signaling; CRF2 agonist. ≥95% 4449.31 C194H338N63O54S1 CCC(C)C(C(=O)NC(C(C)C)C(=O)NC(CC(C)C)C(=O)NC(CO)C(=O)NC(CC(C)C)C(=O)NC(CC(=O)O)C(=O)NC(C(C)C)C(=O)N1CCCC1C(=O)NC(C(C)CC)C(=O)NCC(=O)NC(CC(C)C)C(=O)NC(CC(C)C)C(=O)NC(CCC(=O)N)C(=O)NC(C(C)CC)C(=O)NC(CC(C)C)C(=O)NC(CC(C)C)C(=O)NC(CCC(=O)O)C(=O)NC(CCC(=O)N)C(=O)NC(C)C(=O)NC(CCCNC(=N)N)C(=O)NC(C)C(=O)NC(CCCNC(=N)N)C(=O)NC(C)C(=O)NC(C)C(=O)NC(CCCNC(=N)N)C(=O)NC(CCC(=O)O)C(=O)NC(CCC(=O)N)C(=O)NC(C)C(=O)NC(C(C)O)C(=O)NC(C(C)O)C(=O)NC(CC(=O)N)C(=O)NC(C)C(=O)NC(CCCNC(=N)N)C(=O)NC(C(C)CC)C(=O)NC(CC(C)C)C(=O)NC(C)C(=O)NC(CCCNC(=N)N)C(=O)NC(C(C)C)C(=O)NCC(=O)NC(CC2=CN=CN2)C(=O)NC(CS)C(=O)N)N Ambient -20°C "Campos-Salinas J, Caro M, Cavazzuti A, et al. Protective Role of the Neuropeptide Urocortin II against Experimental Sepsis and Leishmaniasis by Direct Killing of Pathogens. J Immunol. 2013 Dec 15;191(12):6040-51. PMID: 24249730.

 

Grossini E, Caimmi PP, Molinari C, et al. Modulation of calcium movements by urocortin II in endothelial cells. Cell Physiol Biochem. 2010;25(2-3):221-32. PMID: 20110683.

 

Grossini E, Molinari C, Mary DA, et al. The effect of urocortin II administration on the coronary circulation and cardiac function in the anaesthetized pig is nitric-oxide-dependent. Eur J Pharmacol. 2008 Jan 14;578(2-3):242-8. PMID: 17936748.

 

Takahashi K, Totsune K, Murakami O, et al. Urocortins as cardiovascular peptides. Peptides. 2004 Oct;25(10):1723-31. PMID: 15476939.

 

Suda T, Kageyama K, Sakihara S, et al. Physiological roles of urocortins, human homologues of fish urotensin I, and their receptors. Peptides. 2004 Oct;25(10):1689-701. PMID: 15476936.

" Not dangerous goods.

LKT U6856 Urocortin II, human 1 mg 714.2 Endogenous peptide, involved in stress signaling; CRF2 agonist. ≥95% 4449.31 C194H338N63O54S1 CCC(C)C(C(=O)NC(C(C)C)C(=O)NC(CC(C)C)C(=O)NC(CO)C(=O)NC(CC(C)C)C(=O)NC(CC(=O)O)C(=O)NC(C(C)C)C(=O)N1CCCC1C(=O)NC(C(C)CC)C(=O)NCC(=O)NC(CC(C)C)C(=O)NC(CC(C)C)C(=O)NC(CCC(=O)N)C(=O)NC(C(C)CC)C(=O)NC(CC(C)C)C(=O)NC(CC(C)C)C(=O)NC(CCC(=O)O)C(=O)NC(CCC(=O)N)C(=O)NC(C)C(=O)NC(CCCNC(=N)N)C(=O)NC(C)C(=O)NC(CCCNC(=N)N)C(=O)NC(C)C(=O)NC(C)C(=O)NC(CCCNC(=N)N)C(=O)NC(CCC(=O)O)C(=O)NC(CCC(=O)N)C(=O)NC(C)C(=O)NC(C(C)O)C(=O)NC(C(C)O)C(=O)NC(CC(=O)N)C(=O)NC(C)C(=O)NC(CCCNC(=N)N)C(=O)NC(C(C)CC)C(=O)NC(CC(C)C)C(=O)NC(C)C(=O)NC(CCCNC(=N)N)C(=O)NC(C(C)C)C(=O)NCC(=O)NC(CC2=CN=CN2)C(=O)NC(CS)C(=O)N)N Ambient -20°C "Campos-Salinas J, Caro M, Cavazzuti A, et al. Protective Role of the Neuropeptide Urocortin II against Experimental Sepsis and Leishmaniasis by Direct Killing of Pathogens. J Immunol. 2013 Dec 15;191(12):6040-51. PMID: 24249730.

 

Grossini E, Caimmi PP, Molinari C, et al. Modulation of calcium movements by urocortin II in endothelial cells. Cell Physiol Biochem. 2010;25(2-3):221-32. PMID: 20110683.

 

Grossini E, Molinari C, Mary DA, et al. The effect of urocortin II administration on the coronary circulation and cardiac function in the anaesthetized pig is nitric-oxide-dependent. Eur J Pharmacol. 2008 Jan 14;578(2-3):242-8. PMID: 17936748.

 

Takahashi K, Totsune K, Murakami O, et al. Urocortins as cardiovascular peptides. Peptides. 2004 Oct;25(10):1723-31. PMID: 15476939.

 

Suda T, Kageyama K, Sakihara S, et al. Physiological roles of urocortins, human homologues of fish urotensin I, and their receptors. Peptides. 2004 Oct;25(10):1689-701. PMID: 15476936.

" Not dangerous goods.

LKT U6856 Urocortin II, human 2.5 mg 1260.1 Endogenous peptide, involved in stress signaling; CRF2 agonist. ≥95% 4449.31 C194H338N63O54S1 CCC(C)C(C(=O)NC(C(C)C)C(=O)NC(CC(C)C)C(=O)NC(CO)C(=O)NC(CC(C)C)C(=O)NC(CC(=O)O)C(=O)NC(C(C)C)C(=O)N1CCCC1C(=O)NC(C(C)CC)C(=O)NCC(=O)NC(CC(C)C)C(=O)NC(CC(C)C)C(=O)NC(CCC(=O)N)C(=O)NC(C(C)CC)C(=O)NC(CC(C)C)C(=O)NC(CC(C)C)C(=O)NC(CCC(=O)O)C(=O)NC(CCC(=O)N)C(=O)NC(C)C(=O)NC(CCCNC(=N)N)C(=O)NC(C)C(=O)NC(CCCNC(=N)N)C(=O)NC(C)C(=O)NC(C)C(=O)NC(CCCNC(=N)N)C(=O)NC(CCC(=O)O)C(=O)NC(CCC(=O)N)C(=O)NC(C)C(=O)NC(C(C)O)C(=O)NC(C(C)O)C(=O)NC(CC(=O)N)C(=O)NC(C)C(=O)NC(CCCNC(=N)N)C(=O)NC(C(C)CC)C(=O)NC(CC(C)C)C(=O)NC(C)C(=O)NC(CCCNC(=N)N)C(=O)NC(C(C)C)C(=O)NCC(=O)NC(CC2=CN=CN2)C(=O)NC(CS)C(=O)N)N Ambient -20°C "Campos-Salinas J, Caro M, Cavazzuti A, et al. Protective Role of the Neuropeptide Urocortin II against Experimental Sepsis and Leishmaniasis by Direct Killing of Pathogens. J Immunol. 2013 Dec 15;191(12):6040-51. PMID: 24249730.

 

Grossini E, Caimmi PP, Molinari C, et al. Modulation of calcium movements by urocortin II in endothelial cells. Cell Physiol Biochem. 2010;25(2-3):221-32. PMID: 20110683.

 

Grossini E, Molinari C, Mary DA, et al. The effect of urocortin II administration on the coronary circulation and cardiac function in the anaesthetized pig is nitric-oxide-dependent. Eur J Pharmacol. 2008 Jan 14;578(2-3):242-8. PMID: 17936748.

 

Takahashi K, Totsune K, Murakami O, et al. Urocortins as cardiovascular peptides. Peptides. 2004 Oct;25(10):1723-31. PMID: 15476939.

 

Suda T, Kageyama K, Sakihara S, et al. Physiological roles of urocortins, human homologues of fish urotensin I, and their receptors. Peptides. 2004 Oct;25(10):1689-701. PMID: 15476936.

" Not dangerous goods.

LKT U6855 Urocortin, rat 0.5 mg 300.1 Endogenous peptide, involved in stress signaling; CRF1/2 agonist. ≥95% 4707.37 C206H338N62O64 Ambient -20°C "Bagosi Z, Csabafi K, Palotai M, et al. The effect of urocortin I on the hypothalamic ACTH secretagogues and its impact on the hypothalamic-pituitary-adrenal axis. Neuropeptides. 2013 Nov 21. pii: S0143-4179(13)00100-5. PMID: 24331779.

 

Dono LM, Currie PJ. The cannabinoid receptor CB1 inverse agonist AM251 potentiates the anxiogenic activity of urocortin I in the basolateral amygdala. Neuropharmacology. 2012 Jan;62(1):192-9. PMID: 21736884.

 

Currie PJ, Coiro CD, Duenas R, et al. Urocortin I inhibits the effects of ghrelin and neuropeptide Y on feeding and energy substrate utilization. Brain Res. 2011 Apr 18;1385:127-34. PMID: 21303672.

 

Takahashi K, Totsune K, Murakami O, et al. Urocortins as cardiovascular peptides. Peptides. 2004 Oct;25(10):1723-31. PMID: 15476939.

 

Suda T, Kageyama K, Sakihara S, et al. Physiological roles of urocortins, human homologues of fish urotensin I, and their receptors. Peptides. 2004 Oct;25(10):1689-701. PMID: 15476936.

" Not dangerous goods.

LKT U6855 Urocortin, rat 1 mg 510 Endogenous peptide, involved in stress signaling; CRF1/2 agonist. ≥95% 4707.37 C206H338N62O64 Ambient -20°C "Bagosi Z, Csabafi K, Palotai M, et al. The effect of urocortin I on the hypothalamic ACTH secretagogues and its impact on the hypothalamic-pituitary-adrenal axis. Neuropeptides. 2013 Nov 21. pii: S0143-4179(13)00100-5. PMID: 24331779.

 

Dono LM, Currie PJ. The cannabinoid receptor CB1 inverse agonist AM251 potentiates the anxiogenic activity of urocortin I in the basolateral amygdala. Neuropharmacology. 2012 Jan;62(1):192-9. PMID: 21736884.

 

Currie PJ, Coiro CD, Duenas R, et al. Urocortin I inhibits the effects of ghrelin and neuropeptide Y on feeding and energy substrate utilization. Brain Res. 2011 Apr 18;1385:127-34. PMID: 21303672.

 

Takahashi K, Totsune K, Murakami O, et al. Urocortins as cardiovascular peptides. Peptides. 2004 Oct;25(10):1723-31. PMID: 15476939.

 

Suda T, Kageyama K, Sakihara S, et al. Physiological roles of urocortins, human homologues of fish urotensin I, and their receptors. Peptides. 2004 Oct;25(10):1689-701. PMID: 15476936.

" Not dangerous goods.

LKT U6855 Urocortin, rat 2.5 mg 900.1 Endogenous peptide, involved in stress signaling; CRF1/2 agonist. ≥95% 4707.37 C206H338N62O64 Ambient -20°C "Bagosi Z, Csabafi K, Palotai M, et al. The effect of urocortin I on the hypothalamic ACTH secretagogues and its impact on the hypothalamic-pituitary-adrenal axis. Neuropeptides. 2013 Nov 21. pii: S0143-4179(13)00100-5. PMID: 24331779.

 

Dono LM, Currie PJ. The cannabinoid receptor CB1 inverse agonist AM251 potentiates the anxiogenic activity of urocortin I in the basolateral amygdala. Neuropharmacology. 2012 Jan;62(1):192-9. PMID: 21736884.

 

Currie PJ, Coiro CD, Duenas R, et al. Urocortin I inhibits the effects of ghrelin and neuropeptide Y on feeding and energy substrate utilization. Brain Res. 2011 Apr 18;1385:127-34. PMID: 21303672.

 

Takahashi K, Totsune K, Murakami O, et al. Urocortins as cardiovascular peptides. Peptides. 2004 Oct;25(10):1723-31. PMID: 15476939.

 

Suda T, Kageyama K, Sakihara S, et al. Physiological roles of urocortins, human homologues of fish urotensin I, and their receptors. Peptides. 2004 Oct;25(10):1689-701. PMID: 15476936.

" Not dangerous goods.

LKT U6854 Urocortin, human 0.5 mg 300.1 Endogenous peptide hormone, involved in feeding behavior; CRF1/2 agonist. 171543-83-2 ≥98% 4696.3 C204H337N63O64 CCC(C)C(C(=O)NC(C(C)CC)C(=O)NC(CC1=CC=CC=C1)C(=O)NC(CC(=O)O)C(=O)NC(CO)C(=O)NC(C(C)C)C(=O)N)NC(=O)C(CCCN=C(N)N)NC(=O)C(CC(=O)N)NC(=O)C(CCC(=O)N)NC(=O)C(CCC(=O)O)NC(=O)C(C)NC(=O)C(CCCN=C(N)N)NC(=O)C(CCC(=O)O)NC(=O)C(CCCN=C(N)N)NC(=O)C(CCC(=O)N)NC(=O)C(CO)NC(=O)C(CCC(=O)N)NC(=O)C(C(C)O)NC(=O)C(CCCN=C(N)N)NC(=O)C(C)NC(=O)C(CC(C)C)NC(=O)C(CCC(=O)O)NC(=O)C(CC(C)C)NC(=O)C(CC(C)C)NC(=O)C(C(C)O)NC(=O)C(CCCN=C(N)N)NC(=O)C(CC(C)C)NC(=O)C(CC(C)C)NC(=O)C(CC2=CNC=N2)NC(=O)C(CC3=CC=CC=C3)NC(=O)C(C(C)O)NC(=O)C(CC(C)C)NC(=O)C(CC(=O)O)NC(=O)C(C(C)CC)NC(=O)C(CO)NC(=O)C(CC(C)C)NC(=O)C(CO)NC(=O)C4CCCN4C(=O)C(CC(=O)N)NC(=O)C(CC(=O)O)N Ambient -20°C Insoluble in water. "Bagosi Z, Csabafi K, Palotai M, et al. The effect of urocortin I on the hypothalamic ACTH secretagogues and its impact on the hypothalamic-pituitary-adrenal axis. Neuropeptides. 2013 Nov 21. pii: S0143-4179(13)00100-5. PMID: 24331779.

 

Dono LM, Currie PJ. The cannabinoid receptor CB1 inverse agonist AM251 potentiates the anxiogenic activity of urocortin I in the basolateral amygdala. Neuropharmacology. 2012 Jan;62(1):192-9. PMID: 21736884.

 

Currie PJ, Coiro CD, Duenas R, et al. Urocortin I inhibits the effects of ghrelin and neuropeptide Y on feeding and energy substrate utilization. Brain Res. 2011 Apr 18;1385:127-34. PMID: 21303672.

 

Takahashi K, Totsune K, Murakami O, et al. Urocortins as cardiovascular peptides. Peptides. 2004 Oct;25(10):1723-31. PMID: 15476939.

 

Suda T, Kageyama K, Sakihara S, et al. Physiological roles of urocortins, human homologues of fish urotensin I, and their receptors. Peptides. 2004 Oct;25(10):1689-701. PMID: 15476936.

" Not dangerous goods.

LKT U6854 Urocortin, human 1 mg 510 Endogenous peptide hormone, involved in feeding behavior; CRF1/2 agonist. 171543-83-2 ≥98% 4696.3 C204H337N63O64 CCC(C)C(C(=O)NC(C(C)CC)C(=O)NC(CC1=CC=CC=C1)C(=O)NC(CC(=O)O)C(=O)NC(CO)C(=O)NC(C(C)C)C(=O)N)NC(=O)C(CCCN=C(N)N)NC(=O)C(CC(=O)N)NC(=O)C(CCC(=O)N)NC(=O)C(CCC(=O)O)NC(=O)C(C)NC(=O)C(CCCN=C(N)N)NC(=O)C(CCC(=O)O)NC(=O)C(CCCN=C(N)N)NC(=O)C(CCC(=O)N)NC(=O)C(CO)NC(=O)C(CCC(=O)N)NC(=O)C(C(C)O)NC(=O)C(CCCN=C(N)N)NC(=O)C(C)NC(=O)C(CC(C)C)NC(=O)C(CCC(=O)O)NC(=O)C(CC(C)C)NC(=O)C(CC(C)C)NC(=O)C(C(C)O)NC(=O)C(CCCN=C(N)N)NC(=O)C(CC(C)C)NC(=O)C(CC(C)C)NC(=O)C(CC2=CNC=N2)NC(=O)C(CC3=CC=CC=C3)NC(=O)C(C(C)O)NC(=O)C(CC(C)C)NC(=O)C(CC(=O)O)NC(=O)C(C(C)CC)NC(=O)C(CO)NC(=O)C(CC(C)C)NC(=O)C(CO)NC(=O)C4CCCN4C(=O)C(CC(=O)N)NC(=O)C(CC(=O)O)N Ambient -20°C Insoluble in water. "Bagosi Z, Csabafi K, Palotai M, et al. The effect of urocortin I on the hypothalamic ACTH secretagogues and its impact on the hypothalamic-pituitary-adrenal axis. Neuropeptides. 2013 Nov 21. pii: S0143-4179(13)00100-5. PMID: 24331779.

 

Dono LM, Currie PJ. The cannabinoid receptor CB1 inverse agonist AM251 potentiates the anxiogenic activity of urocortin I in the basolateral amygdala. Neuropharmacology. 2012 Jan;62(1):192-9. PMID: 21736884.

 

Currie PJ, Coiro CD, Duenas R, et al. Urocortin I inhibits the effects of ghrelin and neuropeptide Y on feeding and energy substrate utilization. Brain Res. 2011 Apr 18;1385:127-34. PMID: 21303672.

 

Takahashi K, Totsune K, Murakami O, et al. Urocortins as cardiovascular peptides. Peptides. 2004 Oct;25(10):1723-31. PMID: 15476939.

 

Suda T, Kageyama K, Sakihara S, et al. Physiological roles of urocortins, human homologues of fish urotensin I, and their receptors. Peptides. 2004 Oct;25(10):1689-701. PMID: 15476936.

" Not dangerous goods.

LKT U6854 Urocortin, human 2.5 mg 900.1 Endogenous peptide hormone, involved in feeding behavior; CRF1/2 agonist. 171543-83-2 ≥98% 4696.3 C204H337N63O64 CCC(C)C(C(=O)NC(C(C)CC)C(=O)NC(CC1=CC=CC=C1)C(=O)NC(CC(=O)O)C(=O)NC(CO)C(=O)NC(C(C)C)C(=O)N)NC(=O)C(CCCN=C(N)N)NC(=O)C(CC(=O)N)NC(=O)C(CCC(=O)N)NC(=O)C(CCC(=O)O)NC(=O)C(C)NC(=O)C(CCCN=C(N)N)NC(=O)C(CCC(=O)O)NC(=O)C(CCCN=C(N)N)NC(=O)C(CCC(=O)N)NC(=O)C(CO)NC(=O)C(CCC(=O)N)NC(=O)C(C(C)O)NC(=O)C(CCCN=C(N)N)NC(=O)C(C)NC(=O)C(CC(C)C)NC(=O)C(CCC(=O)O)NC(=O)C(CC(C)C)NC(=O)C(CC(C)C)NC(=O)C(C(C)O)NC(=O)C(CCCN=C(N)N)NC(=O)C(CC(C)C)NC(=O)C(CC(C)C)NC(=O)C(CC2=CNC=N2)NC(=O)C(CC3=CC=CC=C3)NC(=O)C(C(C)O)NC(=O)C(CC(C)C)NC(=O)C(CC(=O)O)NC(=O)C(C(C)CC)NC(=O)C(CO)NC(=O)C(CC(C)C)NC(=O)C(CO)NC(=O)C4CCCN4C(=O)C(CC(=O)N)NC(=O)C(CC(=O)O)N Ambient -20°C Insoluble in water. "Bagosi Z, Csabafi K, Palotai M, et al. The effect of urocortin I on the hypothalamic ACTH secretagogues and its impact on the hypothalamic-pituitary-adrenal axis. Neuropeptides. 2013 Nov 21. pii: S0143-4179(13)00100-5. PMID: 24331779.

 

Dono LM, Currie PJ. The cannabinoid receptor CB1 inverse agonist AM251 potentiates the anxiogenic activity of urocortin I in the basolateral amygdala. Neuropharmacology. 2012 Jan;62(1):192-9. PMID: 21736884.

 

Currie PJ, Coiro CD, Duenas R, et al. Urocortin I inhibits the effects of ghrelin and neuropeptide Y on feeding and energy substrate utilization. Brain Res. 2011 Apr 18;1385:127-34. PMID: 21303672.

 

Takahashi K, Totsune K, Murakami O, et al. Urocortins as cardiovascular peptides. Peptides. 2004 Oct;25(10):1723-31. PMID: 15476939.

 

Suda T, Kageyama K, Sakihara S, et al. Physiological roles of urocortins, human homologues of fish urotensin I, and their receptors. Peptides. 2004 Oct;25(10):1689-701. PMID: 15476936.

" Not dangerous goods.

LKT U6802 Urapidil Hydrochloride 500 mg 92.5 5-HT1A agonist, α1-adrenergic antagonist. "2,4(1H,3H)-Pyrimidinedione,6-((3-(4-(2-methoxy- phenyl)-1-piperazinyl)propyl)amino)-1,3-dimethyl-, monohydrochloride 

 

" Ebrantil 64887-14-5 ≥98% 423.93 C20H29N5O3 HCl CN1C(=CC(=O)N(C1=O)C)NCCCN2CCN(CC2)C3=CC=CC=C3OC.Cl Ambient Ambient Soluble in water. "Santiveri X, Ledesma M. Urapidil in anesthesiology: pharmacology and indications. Rev Esp Anestesiol Reanim. 1998 May;45(5):189-97. PMID: 9646668.

 

van Zwieten PA, Chalmers JP. Different types of centrally acting antihypertensives and their targets in the central nervous system. Cardiovasc Drugs Ther. 1994 Dec;8(6):787-99. PMID: 7742257.

" Xn Not dangerous goods.

LKT U6802 Urapidil Hydrochloride 1 g 150.4 5-HT1A agonist, α1-adrenergic antagonist. "2,4(1H,3H)-Pyrimidinedione,6-((3-(4-(2-methoxy- phenyl)-1-piperazinyl)propyl)amino)-1,3-dimethyl-, monohydrochloride 

 

" Ebrantil 64887-14-5 ≥98% 423.93 C20H29N5O3 HCl CN1C(=CC(=O)N(C1=O)C)NCCCN2CCN(CC2)C3=CC=CC=C3OC.Cl Ambient Ambient Soluble in water. "Santiveri X, Ledesma M. Urapidil in anesthesiology: pharmacology and indications. Rev Esp Anestesiol Reanim. 1998 May;45(5):189-97. PMID: 9646668.

 

van Zwieten PA, Chalmers JP. Different types of centrally acting antihypertensives and their targets in the central nervous system. Cardiovasc Drugs Ther. 1994 Dec;8(6):787-99. PMID: 7742257.

" Xn Not dangerous goods.

LKT U6802 Urapidil Hydrochloride 5 g 577.6 5-HT1A agonist, α1-adrenergic antagonist. "2,4(1H,3H)-Pyrimidinedione,6-((3-(4-(2-methoxy- phenyl)-1-piperazinyl)propyl)amino)-1,3-dimethyl-, monohydrochloride 

 

" Ebrantil 64887-14-5 ≥98% 423.93 C20H29N5O3 HCl CN1C(=CC(=O)N(C1=O)C)NCCCN2CCN(CC2)C3=CC=CC=C3OC.Cl Ambient Ambient Soluble in water. "Santiveri X, Ledesma M. Urapidil in anesthesiology: pharmacology and indications. Rev Esp Anestesiol Reanim. 1998 May;45(5):189-97. PMID: 9646668.

 

van Zwieten PA, Chalmers JP. Different types of centrally acting antihypertensives and their targets in the central nervous system. Cardiovasc Drugs Ther. 1994 Dec;8(6):787-99. PMID: 7742257.

" Xn Not dangerous goods.

LKT C2844 Chloramphenicol 5 g 32.3 Protein translation inhibitor, peptidyl transferase inhibitor. "Acetamide, 2,2-dichloro-N-((1R,2R)-2-hydroxy-1-

(hydroxymethyl)-2-(4-nitrophenyl)ethyl)- " Chloromyxin; Ophthochlor; Ophthocort. 56-75-7 ≥98% 323.13 C11H12Cl2N2O5 C1=CC(=CC=C1C(C(CO)NC(=O)C(Cl)Cl)O)[N+](=O)[O-] Ambient Ambient Slightly soluble in water (2.5 mg/ml). Very soluble in methanol, ethanol, ethyl acetate, acetone. "Sheth A, Escobar-Alvarez S, Gardner J, et al. Inhibition of human mitochondrial peptide deformylase causes apoptosis in c-myc-overexpressing hematopoietic cancers. Cell Death Dis. 2014 Mar 27;5:e1152. PMID: 24675470.

 

Rajesh T, Song E, Lee BR, et al. Increased sensitivity to chloramphenicol by inactivation of manB in Streptomyces coelicolor. J Microbiol Biotechnol. 2012 Oct;22(10):1324-9. PMID: 23075781.

 

Wilson DN. On the specificity of antibiotics targeting the large ribosomal subunit. Ann N Y Acad Sci. 2011 Dec;1241:1-16. PMID: 22191523.

" T Not dangerous goods.

LKT U6801 Urapidil 500 mg 82.4 5-HT1A agonist, α1-adrenergic antagonist. 6-[[3-[4-(2-Methoxyphenyl)-1-piperazinyl]propyl]- amino]-1,3-dimethyl-2,4(1H,3H)-pyrimidinedione Ebrantil 34661-75-1 ≥98% 387.48 C20H29N5O3 CN1C(=CC(=O)N(C1=O)C)NCCCN2CCN(CC2)C3=CC=CC=C3OC Ambient Ambient Soluble in H2O. "Santiveri X, Ledesma M. Urapidil in anesthesiology: pharmacology and indications. Rev Esp Anestesiol Reanim. 1998 May;45(5):189-97. PMID: 9646668.

 

van Zwieten PA, Chalmers JP. Different types of centrally acting antihypertensives and their targets in the central nervous system. Cardiovasc Drugs Ther. 1994 Dec;8(6):787-99. PMID: 7742257.

" Not dangerous goods.

LKT C2844 Chloramphenicol 10 g 45.3 Protein translation inhibitor, peptidyl transferase inhibitor. "Acetamide, 2,2-dichloro-N-((1R,2R)-2-hydroxy-1-

(hydroxymethyl)-2-(4-nitrophenyl)ethyl)- " Chloromyxin; Ophthochlor; Ophthocort. 56-75-7 ≥98% 323.13 C11H12Cl2N2O5 C1=CC(=CC=C1C(C(CO)NC(=O)C(Cl)Cl)O)[N+](=O)[O-] Ambient Ambient Slightly soluble in water (2.5 mg/ml). Very soluble in methanol, ethanol, ethyl acetate, acetone. "Sheth A, Escobar-Alvarez S, Gardner J, et al. Inhibition of human mitochondrial peptide deformylase causes apoptosis in c-myc-overexpressing hematopoietic cancers. Cell Death Dis. 2014 Mar 27;5:e1152. PMID: 24675470.

 

Rajesh T, Song E, Lee BR, et al. Increased sensitivity to chloramphenicol by inactivation of manB in Streptomyces coelicolor. J Microbiol Biotechnol. 2012 Oct;22(10):1324-9. PMID: 23075781.

 

Wilson DN. On the specificity of antibiotics targeting the large ribosomal subunit. Ann N Y Acad Sci. 2011 Dec;1241:1-16. PMID: 22191523.

" T Not dangerous goods.

LKT U6801 Urapidil 1 g 134.1 5-HT1A agonist, α1-adrenergic antagonist. 6-[[3-[4-(2-Methoxyphenyl)-1-piperazinyl]propyl]- amino]-1,3-dimethyl-2,4(1H,3H)-pyrimidinedione Ebrantil 34661-75-1 ≥98% 387.48 C20H29N5O3 CN1C(=CC(=O)N(C1=O)C)NCCCN2CCN(CC2)C3=CC=CC=C3OC Ambient Ambient Soluble in H2O. "Santiveri X, Ledesma M. Urapidil in anesthesiology: pharmacology and indications. Rev Esp Anestesiol Reanim. 1998 May;45(5):189-97. PMID: 9646668.

 

van Zwieten PA, Chalmers JP. Different types of centrally acting antihypertensives and their targets in the central nervous system. Cardiovasc Drugs Ther. 1994 Dec;8(6):787-99. PMID: 7742257.

" Not dangerous goods.

LKT C2844 Chloramphenicol 50 g 129.5 Protein translation inhibitor, peptidyl transferase inhibitor. "Acetamide, 2,2-dichloro-N-((1R,2R)-2-hydroxy-1-

(hydroxymethyl)-2-(4-nitrophenyl)ethyl)- " Chloromyxin; Ophthochlor; Ophthocort. 56-75-7 ≥98% 323.13 C11H12Cl2N2O5 C1=CC(=CC=C1C(C(CO)NC(=O)C(Cl)Cl)O)[N+](=O)[O-] Ambient Ambient Slightly soluble in water (2.5 mg/ml). Very soluble in methanol, ethanol, ethyl acetate, acetone. "Sheth A, Escobar-Alvarez S, Gardner J, et al. Inhibition of human mitochondrial peptide deformylase causes apoptosis in c-myc-overexpressing hematopoietic cancers. Cell Death Dis. 2014 Mar 27;5:e1152. PMID: 24675470.

 

Rajesh T, Song E, Lee BR, et al. Increased sensitivity to chloramphenicol by inactivation of manB in Streptomyces coelicolor. J Microbiol Biotechnol. 2012 Oct;22(10):1324-9. PMID: 23075781.

 

Wilson DN. On the specificity of antibiotics targeting the large ribosomal subunit. Ann N Y Acad Sci. 2011 Dec;1241:1-16. PMID: 22191523.

" T Not dangerous goods.

LKT U6801 Urapidil 5 g 515.7 5-HT1A agonist, α1-adrenergic antagonist. 6-[[3-[4-(2-Methoxyphenyl)-1-piperazinyl]propyl]- amino]-1,3-dimethyl-2,4(1H,3H)-pyrimidinedione Ebrantil 34661-75-1 ≥98% 387.48 C20H29N5O3 CN1C(=CC(=O)N(C1=O)C)NCCCN2CCN(CC2)C3=CC=CC=C3OC Ambient Ambient Soluble in H2O. "Santiveri X, Ledesma M. Urapidil in anesthesiology: pharmacology and indications. Rev Esp Anestesiol Reanim. 1998 May;45(5):189-97. PMID: 9646668.

 

van Zwieten PA, Chalmers JP. Different types of centrally acting antihypertensives and their targets in the central nervous system. Cardiovasc Drugs Ther. 1994 Dec;8(6):787-99. PMID: 7742257.

" Not dangerous goods.

LKT C2845 Levo-Chloramphenicol 5 g 46.4 Protein translation inhibitor, peptidyl transferase inhibitor. "Acetamide, 2,2-dichloro-N-((1R,2R)-2-hydroxy-1-

(hydroxymethyl)-2-(4-nitrophenyl)ethyl)- 

" Chloromyxin; Ophthochlor; Ophthocort. 56-75-7 ≥98% 323.13 C11H12Cl2N2O5 C1=CC(=CC=C1C(C(CO)NC(=O)C(Cl)Cl)O)[N+](=O)[O-] Ambient Ambient Soluble in methanol, ethanol or acetone. "Sheth A, Escobar-Alvarez S, Gardner J, et al. Inhibition of human mitochondrial peptide deformylase causes apoptosis in c-myc-overexpressing hematopoietic cancers. Cell Death Dis. 2014 Mar 27;5:e1152. PMID: 24675470.

 

Rajesh T, Song E, Lee BR, et al. Increased sensitivity to chloramphenicol by inactivation of manB in Streptomyces coelicolor. J Microbiol Biotechnol. 2012 Oct;22(10):1324-9. PMID: 23075781.

 

Wilson DN. On the specificity of antibiotics targeting the large ribosomal subunit. Ann N Y Acad Sci. 2011 Dec;1241:1-16. PMID: 22191523.

" Carc. Cat. 1, Carc. Cat. 2 Not dangerous goods.

LKT C2845 Levo-Chloramphenicol 10 g 79.8 Protein translation inhibitor, peptidyl transferase inhibitor. "Acetamide, 2,2-dichloro-N-((1R,2R)-2-hydroxy-1-

(hydroxymethyl)-2-(4-nitrophenyl)ethyl)- 

" Chloromyxin; Ophthochlor; Ophthocort. 56-75-7 ≥98% 323.13 C11H12Cl2N2O5 C1=CC(=CC=C1C(C(CO)NC(=O)C(Cl)Cl)O)[N+](=O)[O-] Ambient Ambient Soluble in methanol, ethanol or acetone. "Sheth A, Escobar-Alvarez S, Gardner J, et al. Inhibition of human mitochondrial peptide deformylase causes apoptosis in c-myc-overexpressing hematopoietic cancers. Cell Death Dis. 2014 Mar 27;5:e1152. PMID: 24675470.

 

Rajesh T, Song E, Lee BR, et al. Increased sensitivity to chloramphenicol by inactivation of manB in Streptomyces coelicolor. J Microbiol Biotechnol. 2012 Oct;22(10):1324-9. PMID: 23075781.

 

Wilson DN. On the specificity of antibiotics targeting the large ribosomal subunit. Ann N Y Acad Sci. 2011 Dec;1241:1-16. PMID: 22191523.

" Carc. Cat. 1, Carc. Cat. 2 Not dangerous goods.

LKT C2845 Levo-Chloramphenicol 50 g 189 Protein translation inhibitor, peptidyl transferase inhibitor. "Acetamide, 2,2-dichloro-N-((1R,2R)-2-hydroxy-1-

(hydroxymethyl)-2-(4-nitrophenyl)ethyl)- 

" Chloromyxin; Ophthochlor; Ophthocort. 56-75-7 ≥98% 323.13 C11H12Cl2N2O5 C1=CC(=CC=C1C(C(CO)NC(=O)C(Cl)Cl)O)[N+](=O)[O-] Ambient Ambient Soluble in methanol, ethanol or acetone. "Sheth A, Escobar-Alvarez S, Gardner J, et al. Inhibition of human mitochondrial peptide deformylase causes apoptosis in c-myc-overexpressing hematopoietic cancers. Cell Death Dis. 2014 Mar 27;5:e1152. PMID: 24675470.

 

Rajesh T, Song E, Lee BR, et al. Increased sensitivity to chloramphenicol by inactivation of manB in Streptomyces coelicolor. J Microbiol Biotechnol. 2012 Oct;22(10):1324-9. PMID: 23075781.

 

Wilson DN. On the specificity of antibiotics targeting the large ribosomal subunit. Ann N Y Acad Sci. 2011 Dec;1241:1-16. PMID: 22191523.

" Carc. Cat. 1, Carc. Cat. 2 Not dangerous goods.

LKT U6118 Uperolein 1 mg 132 Peptide found in amphibian skin; NK-1 agonist. ≥95% 1234.42 C57H79N13O16S CC(C)CC(C(=O)NC(CCSC)C(=O)N)NC(=O)CNC(=O)C(CC1=CC=C(C=C1)O)NC(=O)C(CC2=CC=CC=C2)NC(=O)C(C)NC(=O)C(CC(=O)N)NC(=O)C3CCCN3C(=O)C(CO)NC(=O)C4CCCN4C(=O)C5CCC(=O)N5 Ambient -20°C "Dike A, Cowsik SM. Solution structure of amphibian tachykinin Uperolein bound to DPC micelles. J Struct Biol. 2006 Dec;156(3):442-52. PMID: 16979908.

 

Bertaccini G, Coruzzi G. Action of some natural peptides on the stomach of the anaesthetized rat. Naunyn Schmiedebergs Arch Pharmacol. 1977 Jun;298(2):163-6. PMID: 882154.

 

Erspamer V, Negri L, Erspamer GF, et al. Uperolein and other active peptides in the skin of the Australian leptodactylid frogs Uperoleia and Taudactylus. Naunyn Schmiedebergs Arch Pharmacol. 1975;289(1):41-54. PMID: 1186916.

"

LKT U6118 Uperolein 2 mg 225 Peptide found in amphibian skin; NK-1 agonist. ≥95% 1234.42 C57H79N13O16S CC(C)CC(C(=O)NC(CCSC)C(=O)N)NC(=O)CNC(=O)C(CC1=CC=C(C=C1)O)NC(=O)C(CC2=CC=CC=C2)NC(=O)C(C)NC(=O)C(CC(=O)N)NC(=O)C3CCCN3C(=O)C(CO)NC(=O)C4CCCN4C(=O)C5CCC(=O)N5 Ambient -20°C "Dike A, Cowsik SM. Solution structure of amphibian tachykinin Uperolein bound to DPC micelles. J Struct Biol. 2006 Dec;156(3):442-52. PMID: 16979908.

 

Bertaccini G, Coruzzi G. Action of some natural peptides on the stomach of the anaesthetized rat. Naunyn Schmiedebergs Arch Pharmacol. 1977 Jun;298(2):163-6. PMID: 882154.

 

Erspamer V, Negri L, Erspamer GF, et al. Uperolein and other active peptides in the skin of the Australian leptodactylid frogs Uperoleia and Taudactylus. Naunyn Schmiedebergs Arch Pharmacol. 1975;289(1):41-54. PMID: 1186916.

"

LKT C2847 Chlormadinone Acetate 1 g 168.5 Synthetic steroid hormone; AR and ER antagonist. 17-(Acetyloxy)-6-chloropregna-4,6-diene-3,20-dione Chronosynl Cyclonorm; Fertiletten; Lormin; Luteran; Matrol; Normenon; Prostal; Traslan 302-22-7 ≥96% 404.93 C23H29ClO4 CC(=O)C1(CCC2C1(CCC3C2C=C(C4=CC(=O)CCC34C)Cl)C)OC(=O)C Ambient Ambient Soluble in methanol or ether. "Kim JM, Lee JE, Ryu SH, et al. Chlormadinone acetate promotes osteoblast differentiation of human mesenchymal stem cells through the ERK signaling pathway. Eur J Pharmacol. 2014 Mar 5;726:1-8. PMID: 24440171.

 

Fujimoto K, Hirao Y, Ohashi Y, et al. The effects of chlormadinone acetate on lower urinary tract symptoms and erectile functions of patients with benign prostatic hyperplasia: a prospective multicenter clinical study. Adv Urol. 2013;2013:584678. PMID: 23762042.

 

Gomes VA, Vieira CS, Jacob-Ferreira AL, et al. Oral contraceptive containing chlormadinone acetate and ethinylestradiol reduces plasma concentrations of matrix metalloproteinase-2 in women with polycystic ovary syndrome. Basic Clin Pharmacol Toxicol. 2012 Sep;111(3):211-6. PMID: 22510229.

" T Not dangerous goods.

LKT C2847 Chlormadinone Acetate 5 g 730.3 Synthetic steroid hormone; AR and ER antagonist. 17-(Acetyloxy)-6-chloropregna-4,6-diene-3,20-dione Chronosynl Cyclonorm; Fertiletten; Lormin; Luteran; Matrol; Normenon; Prostal; Traslan 302-22-7 ≥96% 404.93 C23H29ClO4 CC(=O)C1(CCC2C1(CCC3C2C=C(C4=CC(=O)CCC34C)Cl)C)OC(=O)C Ambient Ambient Soluble in methanol or ether. "Kim JM, Lee JE, Ryu SH, et al. Chlormadinone acetate promotes osteoblast differentiation of human mesenchymal stem cells through the ERK signaling pathway. Eur J Pharmacol. 2014 Mar 5;726:1-8. PMID: 24440171.

 

Fujimoto K, Hirao Y, Ohashi Y, et al. The effects of chlormadinone acetate on lower urinary tract symptoms and erectile functions of patients with benign prostatic hyperplasia: a prospective multicenter clinical study. Adv Urol. 2013;2013:584678. PMID: 23762042.

 

Gomes VA, Vieira CS, Jacob-Ferreira AL, et al. Oral contraceptive containing chlormadinone acetate and ethinylestradiol reduces plasma concentrations of matrix metalloproteinase-2 in women with polycystic ovary syndrome. Basic Clin Pharmacol Toxicol. 2012 Sep;111(3):211-6. PMID: 22510229.

" T Not dangerous goods.

LKT U6118 Uperolein 5 mg 396.1 Peptide found in amphibian skin; NK-1 agonist. ≥95% 1234.42 C57H79N13O16S CC(C)CC(C(=O)NC(CCSC)C(=O)N)NC(=O)CNC(=O)C(CC1=CC=C(C=C1)O)NC(=O)C(CC2=CC=CC=C2)NC(=O)C(C)NC(=O)C(CC(=O)N)NC(=O)C3CCCN3C(=O)C(CO)NC(=O)C4CCCN4C(=O)C5CCC(=O)N5 Ambient -20°C "Dike A, Cowsik SM. Solution structure of amphibian tachykinin Uperolein bound to DPC micelles. J Struct Biol. 2006 Dec;156(3):442-52. PMID: 16979908.

 

Bertaccini G, Coruzzi G. Action of some natural peptides on the stomach of the anaesthetized rat. Naunyn Schmiedebergs Arch Pharmacol. 1977 Jun;298(2):163-6. PMID: 882154.

 

Erspamer V, Negri L, Erspamer GF, et al. Uperolein and other active peptides in the skin of the Australian leptodactylid frogs Uperoleia and Taudactylus. Naunyn Schmiedebergs Arch Pharmacol. 1975;289(1):41-54. PMID: 1186916.

"

LKT C2916 Chenodeoxycholic Acid 1 g 43.5 Endogenous bile acid; FXR agonist. (3α,5β,7α)-3,7-Dihydroxycholan-24-oic acid Chenodiol; CDC; Chenix; Chenossil; Fluibil; Hekbilin; Ulmenide 474-25-9 ≥98% 392.57 C24H40O4 CC(CCC(=O)O)C1CCC2C1(CCC3C2C(CC4C3(CCC(C4)O)C)O)C Ambient Ambient Soluble in methanol, acetone, or acetic acid. Practically insoluble in water, or benzene. "Fiorucci S, Mencarelli A, Cipriani S, et al. Activation of the farnesoid-X receptor protects against gastrointestinal injury caused by non-steroidal anti-inflammatory drugs in mice. Br J Pharmacol. 2011 Dec;164(8):1929-38. PMID: 21564085.

 

Horowitz NS, Hua J, Powell MA, et al. Novel cytotoxic agents from an unexpected source: bile acids and ovarian tumor apoptosis. Gynecol Oncol. 2007 Nov;107(2):344-9. PMID: 17720233.

 

Bazzoli F, Malavolti M, Petronelli A, et al. Treatment of constipation with chenodeoxycholic acid. J Int Med Res. 1983;11(2):120-3. PMID: 6852359.

" Xn, Repr. Not dangerous goods.

LKT C2916 Chenodeoxycholic Acid 5 g 130 Endogenous bile acid; FXR agonist. (3α,5β,7α)-3,7-Dihydroxycholan-24-oic acid Chenodiol; CDC; Chenix; Chenossil; Fluibil; Hekbilin; Ulmenide 474-25-9 ≥98% 392.57 C24H40O4 CC(CCC(=O)O)C1CCC2C1(CCC3C2C(CC4C3(CCC(C4)O)C)O)C Ambient Ambient Soluble in methanol, acetone, or acetic acid. Practically insoluble in water, or benzene. "Fiorucci S, Mencarelli A, Cipriani S, et al. Activation of the farnesoid-X receptor protects against gastrointestinal injury caused by non-steroidal anti-inflammatory drugs in mice. Br J Pharmacol. 2011 Dec;164(8):1929-38. PMID: 21564085.

 

Horowitz NS, Hua J, Powell MA, et al. Novel cytotoxic agents from an unexpected source: bile acids and ovarian tumor apoptosis. Gynecol Oncol. 2007 Nov;107(2):344-9. PMID: 17720233.

 

Bazzoli F, Malavolti M, Petronelli A, et al. Treatment of constipation with chenodeoxycholic acid. J Int Med Res. 1983;11(2):120-3. PMID: 6852359.

" Xn, Repr. Not dangerous goods.

LKT C2916 Chenodeoxycholic Acid 25 g 432.3 Endogenous bile acid; FXR agonist. (3α,5β,7α)-3,7-Dihydroxycholan-24-oic acid Chenodiol; CDC; Chenix; Chenossil; Fluibil; Hekbilin; Ulmenide 474-25-9 ≥98% 392.57 C24H40O4 CC(CCC(=O)O)C1CCC2C1(CCC3C2C(CC4C3(CCC(C4)O)C)O)C Ambient Ambient Soluble in methanol, acetone, or acetic acid. Practically insoluble in water, or benzene. "Fiorucci S, Mencarelli A, Cipriani S, et al. Activation of the farnesoid-X receptor protects against gastrointestinal injury caused by non-steroidal anti-inflammatory drugs in mice. Br J Pharmacol. 2011 Dec;164(8):1929-38. PMID: 21564085.

 

Horowitz NS, Hua J, Powell MA, et al. Novel cytotoxic agents from an unexpected source: bile acids and ovarian tumor apoptosis. Gynecol Oncol. 2007 Nov;107(2):344-9. PMID: 17720233.

 

Bazzoli F, Malavolti M, Petronelli A, et al. Treatment of constipation with chenodeoxycholic acid. J Int Med Res. 1983;11(2):120-3. PMID: 6852359.

" Xn, Repr. Not dangerous goods.

LKT C2942 Mechlorethamine Hydrochloride 5 g 121.9 Nitrogen mustard, DNA alkylator. 2-Chloro-N-(2-chloroethyl)-N-methylethanamine, N-Methylbis(2-chloroethyl)amine hydrochloride Nitrogen mustard, Bis(2-Chloroethyl)methylamine 55-86-7 ≥98% 192.51 C5H11Cl2N ClH CN(CCCl)CCCl.Cl Ambient 4°C "Polavarapu A, Stillabower JA, Stubblefield SG, et al. The mechanism of guanine alkylation by nitrogen mustards: a computational study. J Org Chem. 2012 Jul 20;77(14):5914-21. PMID: 22681226.

 

Wang F, Li F, Ganguly M, et al. A bridging water anchors the tethered 5-(3-aminopropyl)-2'-deoxyuridine amine in the DNA major groove proximate to the N+2 C.G base pair: implications for formation of interstrand 5'-GNC-3' cross-links by nitrogen mustards. Biochemistry. 2008 Jul 8;47(27):7147-57. PMID: 18549246.

 

Crater J, Kannan S. Molecular mechanism of nitrogen mustard induced leukocyte(s) chemotaxis. Med Hypotheses. 2007;68(2):318-9. PMID: 16997491.

 

Eder JP Jr, Chan VT, Ng SW, et al. DNA topoisomerase II alpha expression is associated with alkylating agent resistance. Cancer Res. 1995 Dec 15;55(24):6109-16. PMID: 8521401.

" Carc., Muta., C, T+ "UN number: 2928     Class:  6.1 (8)     Packing group:  II

Proper shipping name:  Toxic solids, corrosive, organic, n.o.s. (Chlormethine hydrochloride)

Reportable Quantity (RQ):     Marine pollutant:  No     Poison inhalation hazard:  No"

LKT C2942 Mechlorethamine Hydrochloride 10 g 215.6 Nitrogen mustard, DNA alkylator. 2-Chloro-N-(2-chloroethyl)-N-methylethanamine, N-Methylbis(2-chloroethyl)amine hydrochloride Nitrogen mustard, Bis(2-Chloroethyl)methylamine 55-86-7 ≥98% 192.51 C5H11Cl2N ClH CN(CCCl)CCCl.Cl Ambient 4°C "Polavarapu A, Stillabower JA, Stubblefield SG, et al. The mechanism of guanine alkylation by nitrogen mustards: a computational study. J Org Chem. 2012 Jul 20;77(14):5914-21. PMID: 22681226.

 

Wang F, Li F, Ganguly M, et al. A bridging water anchors the tethered 5-(3-aminopropyl)-2'-deoxyuridine amine in the DNA major groove proximate to the N+2 C.G base pair: implications for formation of interstrand 5'-GNC-3' cross-links by nitrogen mustards. Biochemistry. 2008 Jul 8;47(27):7147-57. PMID: 18549246.

 

Crater J, Kannan S. Molecular mechanism of nitrogen mustard induced leukocyte(s) chemotaxis. Med Hypotheses. 2007;68(2):318-9. PMID: 16997491.

 

Eder JP Jr, Chan VT, Ng SW, et al. DNA topoisomerase II alpha expression is associated with alkylating agent resistance. Cancer Res. 1995 Dec 15;55(24):6109-16. PMID: 8521401.

" Carc., Muta., C, T+ "UN number: 2928     Class:  6.1 (8)     Packing group:  II

Proper shipping name:  Toxic solids, corrosive, organic, n.o.s. (Chlormethine hydrochloride)

Reportable Quantity (RQ):     Marine pollutant:  No     Poison inhalation hazard:  No"

LKT C2942 Mechlorethamine Hydrochloride 25 g 375.1 Nitrogen mustard, DNA alkylator. 2-Chloro-N-(2-chloroethyl)-N-methylethanamine, N-Methylbis(2-chloroethyl)amine hydrochloride Nitrogen mustard, Bis(2-Chloroethyl)methylamine 55-86-7 ≥98% 192.51 C5H11Cl2N ClH CN(CCCl)CCCl.Cl Ambient 4°C "Polavarapu A, Stillabower JA, Stubblefield SG, et al. The mechanism of guanine alkylation by nitrogen mustards: a computational study. J Org Chem. 2012 Jul 20;77(14):5914-21. PMID: 22681226.

 

Wang F, Li F, Ganguly M, et al. A bridging water anchors the tethered 5-(3-aminopropyl)-2'-deoxyuridine amine in the DNA major groove proximate to the N+2 C.G base pair: implications for formation of interstrand 5'-GNC-3' cross-links by nitrogen mustards. Biochemistry. 2008 Jul 8;47(27):7147-57. PMID: 18549246.

 

Crater J, Kannan S. Molecular mechanism of nitrogen mustard induced leukocyte(s) chemotaxis. Med Hypotheses. 2007;68(2):318-9. PMID: 16997491.

 

Eder JP Jr, Chan VT, Ng SW, et al. DNA topoisomerase II alpha expression is associated with alkylating agent resistance. Cancer Res. 1995 Dec 15;55(24):6109-16. PMID: 8521401.

" Carc., Muta., C, T+ "UN number: 2928     Class:  6.1 (8)     Packing group:  II

Proper shipping name:  Toxic solids, corrosive, organic, n.o.s. (Chlormethine hydrochloride)

Reportable Quantity (RQ):     Marine pollutant:  No     Poison inhalation hazard:  No"

LKT U5233 Universal Tetanus Toxin Epitope P2 (830-844) 1 mg 120 Peptide, tetanus toxin epitope. TT (830-844); TT P2 ≥95% 1725.03 C80H129N19O23 Ambient -20°C "Fryauff DJ, Mouzin E, Church LW, et al. Lymphocyte response to tetanus toxin T-cell epitopes: effects of tetanus vaccination and concurrent malaria prophylaxis. Vaccine. 1999 Jan;17(1):59-63. PMID: 10078608.

 

Valmori D, Sabbatini A, Lanzavecchia A, et al. Functional analysis of two tetanus toxin universal T cell epitopes in their interaction with DR1101 and DR1104 alleles. J Immunol. 1994 Mar 15;152(6):2921-9. PMID: 7511633.

"

LKT U5233 Universal Tetanus Toxin Epitope P2 (830-844) 2 mg 204.1 Peptide, tetanus toxin epitope. TT (830-844); TT P2 ≥95% 1725.03 C80H129N19O23 Ambient -20°C "Fryauff DJ, Mouzin E, Church LW, et al. Lymphocyte response to tetanus toxin T-cell epitopes: effects of tetanus vaccination and concurrent malaria prophylaxis. Vaccine. 1999 Jan;17(1):59-63. PMID: 10078608.

 

Valmori D, Sabbatini A, Lanzavecchia A, et al. Functional analysis of two tetanus toxin universal T cell epitopes in their interaction with DR1101 and DR1104 alleles. J Immunol. 1994 Mar 15;152(6):2921-9. PMID: 7511633.

"

LKT U5233 Universal Tetanus Toxin Epitope P2 (830-844) 5 mg 359.9 Peptide, tetanus toxin epitope. TT (830-844); TT P2 ≥95% 1725.03 C80H129N19O23 Ambient -20°C "Fryauff DJ, Mouzin E, Church LW, et al. Lymphocyte response to tetanus toxin T-cell epitopes: effects of tetanus vaccination and concurrent malaria prophylaxis. Vaccine. 1999 Jan;17(1):59-63. PMID: 10078608.

 

Valmori D, Sabbatini A, Lanzavecchia A, et al. Functional analysis of two tetanus toxin universal T cell epitopes in their interaction with DR1101 and DR1104 alleles. J Immunol. 1994 Mar 15;152(6):2921-9. PMID: 7511633.

"

LKT C2943 Chlorogenic Acid (from Eucommia) 250 mg 40.7 Polyphenol derivative of caffeic acid found in Eucommia bark; DNMT and G6P translocase inhibitor, potential pepsin inhibitor. 327-97-9  ≥98% 354.31 C16H18O9 C1C(C(C(CC1(C(=O)O)O)OC(=O)C=CC2=CC(=C(C=C2)O)O)O)O Ambient Ambient "Zeng HJ, Liang HL, You J, et al. Study on the binding of chlorogenic acid to pepsin by spectral and molecular docking. Luminescence. 2013 Dec 12. [Epub ahead of print]. PMID: 24339327.

 

Luís A, Silva F, Sousa S, et al. Antistaphylococcal and biofilm inhibitory activities of gallic, caffeic, and chlorogenic acids. Biofouling. 2014 Jan;30(1):69-79. PMID: 24228999.

 

Shi H, Dong L, Jiang J, et al. Chlorogenic acid reduces liver inflammation and fibrosis through inhibition of toll-like receptor 4 signaling pathway. Toxicology. 2013 Jan 7;303:107-14. PMID: 23146752.

 

Teraoka M, Nakaso K, Kusumoto C, et al. Cytoprotective effect of chlorogenic acid against α-synuclein-related toxicity in catecholaminergic PC12 cells. J Clin Biochem Nutr. 2012 Sep;51(2):122-7. PMID: 22962530.

 

Lou Z, Wang H, Zhu S, et al. Antibacterial activity and mechanism of action of chlorogenic acid. J Food Sci. 2011 Aug;76(6):M398-403. PMID: 22417510.

 

Qin HD, Shi YQ, Liu ZH, et al. Effect of chlorogenic acid on mast cell-dependent anaphylactic reaction. Int Immunopharmacol. 2010 Sep;10(9):1135-41. PMID: 20620227.

 

Belkaid A, Currie JC, Desgagnés J, et al. The chemopreventive properties of chlorogenic acid reveal a potential new role for the microsomal glucose-6-phosphate translocase in brain tumor progression. Cancer Cell Int. 2006 Mar 27;6:7. PMID: 16566826.

 

Lee WJ, Zhu BT. Inhibition of DNA methylation by caffeic acid and chlorogenic acid, two common catechol-containing coffee polyphenols.

" Xn Not dangerous goods.

LKT C2943 Chlorogenic Acid (from Eucommia) 1 g 108.8 Polyphenol derivative of caffeic acid found in Eucommia bark; DNMT and G6P translocase inhibitor, potential pepsin inhibitor. 327-97-9  ≥98% 354.31 C16H18O9 C1C(C(C(CC1(C(=O)O)O)OC(=O)C=CC2=CC(=C(C=C2)O)O)O)O Ambient Ambient "Zeng HJ, Liang HL, You J, et al. Study on the binding of chlorogenic acid to pepsin by spectral and molecular docking. Luminescence. 2013 Dec 12. [Epub ahead of print]. PMID: 24339327.

 

Luís A, Silva F, Sousa S, et al. Antistaphylococcal and biofilm inhibitory activities of gallic, caffeic, and chlorogenic acids. Biofouling. 2014 Jan;30(1):69-79. PMID: 24228999.

 

Shi H, Dong L, Jiang J, et al. Chlorogenic acid reduces liver inflammation and fibrosis through inhibition of toll-like receptor 4 signaling pathway. Toxicology. 2013 Jan 7;303:107-14. PMID: 23146752.

 

Teraoka M, Nakaso K, Kusumoto C, et al. Cytoprotective effect of chlorogenic acid against α-synuclein-related toxicity in catecholaminergic PC12 cells. J Clin Biochem Nutr. 2012 Sep;51(2):122-7. PMID: 22962530.

 

Lou Z, Wang H, Zhu S, et al. Antibacterial activity and mechanism of action of chlorogenic acid. J Food Sci. 2011 Aug;76(6):M398-403. PMID: 22417510.

 

Qin HD, Shi YQ, Liu ZH, et al. Effect of chlorogenic acid on mast cell-dependent anaphylactic reaction. Int Immunopharmacol. 2010 Sep;10(9):1135-41. PMID: 20620227.

 

Belkaid A, Currie JC, Desgagnés J, et al. The chemopreventive properties of chlorogenic acid reveal a potential new role for the microsomal glucose-6-phosphate translocase in brain tumor progression. Cancer Cell Int. 2006 Mar 27;6:7. PMID: 16566826.

 

Lee WJ, Zhu BT. Inhibition of DNA methylation by caffeic acid and chlorogenic acid, two common catechol-containing coffee polyphenols.

" Xn Not dangerous goods.

LKT U5232 Uniconazole 5 g 65.6 Triazole; gibberellin inhibitor, potential 14-α demethylase inhibitor. 83657-22-1 ≥95% 291.78 C15H18ClN3O CC(C)(C)C(C(=CC1=CC=C(C=C1)Cl)N2C=NC=N2)O Ambient Ambient "Sasaki E, Ogura T, Takei K, et al. Uniconazole, a cytochrome P450 inhibitor, inhibits trans-zeatin biosynthesis in Arabidopsis. Phytochemistry. 2013 Mar;87:30-8. PMID: 23280040.

 

Sun J, Zhang A, Zhang J, et al. Enantiomeric resolution and growth-retardant activity in rice seedlings of uniconazole. J Agric Food Chem. 2012 Jan 11;60(1):160-4. PMID: 22148239.

 

Todoroki Y, Kobayashi K, Yoneyama H, et al. Structure-activity relationship of uniconazole, a potent inhibitor of ABA 8'-hydroxylase, with a focus on hydrophilic functional groups and conformation. Bioorg Med Chem. 2008 Mar 15;16(6):3141-52. PMID: 18164621.

 

Saito S, Okamoto M, Shinoda S, et al. A plant growth retardant, uniconazole, is a potent inhibitor of ABA catabolism in Arabidopsis. Biosci Biotechnol Biochem. 2006 Jul;70(7):1731-9. PMID: 16819156.

 

Hays DB, Yeung EC, Pharis RP. The role of gibberellins in embryo axis development. J Exp Bot. 2002 Aug;53(375):1747-51. PMID: 12147724.

" "UN number: 3077     Class: 9     Packing Group: III

Proper shipping name: Environmentally hazardous substance, solid, n.o.s. (Uniconazole)"

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