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LKT B8271 Bursin Tripeptide, adjuvant

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LKT Labs 是一家专注于防癌抗癌特殊化学品研究和开发的公司。主要提供:癌症药物、药物发现试剂盒、天然产物、广泛的生命科学研究试剂、定制合成。
美国LKT Labs 是1988年在美国成立的,为全球提供先端的药物研发试剂、试剂盒、委托合成,并为药物生产企业提供原料,最近几年在农药、水产养殖业有很大程度的开发。LKT B8271 Bursin Tripeptide, adjuvant

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LKT Labs 是一家专注于防癌抗癌特殊化学品研究和开发的公司。主要提供:癌症药物、药物发现试剂盒、天然产物、广泛的生命科学研究试剂、定制合成。
美国LKT Labs 是1988年在美国成立的,为全球提供先端的药物研发试剂、试剂盒、委托合成,并为药物生产企业提供原料,最近几年在农药、水产养殖业有很大程度的开发。在LKT Labs 可以找到在其他地方找不到的产品。

LKT B8271 Bursin Tripeptide, adjuvant

LKT B8271 Bursin Tripeptide, adjuvant

 

LKT A5033 4-Aminosalicylic Acid 500 g 101.9 Dihydrofolate reductase inhibitor. 4-Amino-2-hydroxybenzoic acid p-Aminosalicylic Acid; PASER; Rezipas 65-49-6 ≥98% 153.14 C7H7NO3 C1=CC(=C(C=C1N)O)C(=O)O Ambient Ambient Soluble in water and alcohol. Practically insoluble in benzene.  "Dhaneshwar SS. Colon-specific prodrugs of 4-aminosalicylic acid for inflammatory bowel disease. World J Gastroenterol. 2014 Apr 7;20(13):3564-71. PMID: 24707139.

 

Jensen KA, Rosdahl KG, Ingvorsen H. Tuberculostatic derivatives of rho-aminobenzoic acid; esters and amides of 4-aminosalicylic acid. Acta Chem Scand. 1948;2(3):220-4. PMID: 18098531.

" Xn Not dangerous goods.

LKT A5034 4-Aminosalicylic Sodium Dihydrate 25 g 23.4 Dihydrofolate reductase inhibitor. 4-Amino-2-hydroxybenzoic acid sodium salt dihydrate Aminacyl; Nemasol Sodium; Pamisyl Sodium; Pasalon 6018-19-5 ≥98% 211.15 C7H6NNaO3 2H2O C1=CC(=C(C=C1N)O)C(=O)[O-].O.O.[Na+] Ambient Ambient Soluble in water (500 mg/mL). Sparingly soluble in acetone. Practically insoluble in ether, chloroform and benzene. "Dhaneshwar SS. Colon-specific prodrugs of 4-aminosalicylic acid for inflammatory bowel disease. World J Gastroenterol. 2014 Apr 7;20(13):3564-71. PMID: 24707139.

 

Jensen KA, Rosdahl KG, Ingvorsen H. Tuberculostatic derivatives of rho-aminobenzoic acid; esters and amides of 4-aminosalicylic acid. Acta Chem Scand. 1948;2(3):220-4. PMID: 18098531.

" Xi Not dangerous goods.

LKT A5034 4-Aminosalicylic Sodium Dihydrate 100 g 37.3 Dihydrofolate reductase inhibitor. 4-Amino-2-hydroxybenzoic acid sodium salt dihydrate Aminacyl; Nemasol Sodium; Pamisyl Sodium; Pasalon 6018-19-5 ≥98% 211.15 C7H6NNaO3 2H2O C1=CC(=C(C=C1N)O)C(=O)[O-].O.O.[Na+] Ambient Ambient Soluble in water (500 mg/mL). Sparingly soluble in acetone. Practically insoluble in ether, chloroform and benzene. "Dhaneshwar SS. Colon-specific prodrugs of 4-aminosalicylic acid for inflammatory bowel disease. World J Gastroenterol. 2014 Apr 7;20(13):3564-71. PMID: 24707139.

 

Jensen KA, Rosdahl KG, Ingvorsen H. Tuberculostatic derivatives of rho-aminobenzoic acid; esters and amides of 4-aminosalicylic acid. Acta Chem Scand. 1948;2(3):220-4. PMID: 18098531.

" Xi Not dangerous goods.

LKT A5034 4-Aminosalicylic Sodium Dihydrate 500 g 173.3 Dihydrofolate reductase inhibitor. 4-Amino-2-hydroxybenzoic acid sodium salt dihydrate Aminacyl; Nemasol Sodium; Pamisyl Sodium; Pasalon 6018-19-5 ≥98% 211.15 C7H6NNaO3 2H2O C1=CC(=C(C=C1N)O)C(=O)[O-].O.O.[Na+] Ambient Ambient Soluble in water (500 mg/mL). Sparingly soluble in acetone. Practically insoluble in ether, chloroform and benzene. "Dhaneshwar SS. Colon-specific prodrugs of 4-aminosalicylic acid for inflammatory bowel disease. World J Gastroenterol. 2014 Apr 7;20(13):3564-71. PMID: 24707139.

 

Jensen KA, Rosdahl KG, Ingvorsen H. Tuberculostatic derivatives of rho-aminobenzoic acid; esters and amides of 4-aminosalicylic acid. Acta Chem Scand. 1948;2(3):220-4. PMID: 18098531.

" Xi Not dangerous goods.

LKT A5035 5-Aminosalicylic Acid 25 g 88.3 Salicylic acid derivative; PPARγ agonist, potential COX-1/2 inhibitor. 5-amino-2-hydroxybenzoic acid 5-ASA; Mesalamine; Asacol; Salofalk; 5-amino-2- hydroxybenzoic acid 89-57-6 ≥98% 153.14 C7H7NO3 C1=CC(=C(C=C1N)C(=O)O)O Ambient Ambient "Poh J, Knowles S. Safety of 5-Aminosalicylic Acid Derivatives in Patients with Sensitivity to Acetylsalicylic Acid and Nonsteroidal Anti-inflammatory Drugs. Can J Hosp Pharm. 2014 Jan;67(1):35-8. PMID: 24634525.

 

Managlia E, Katzman RB, Brown JB, et al. Antioxidant properties of mesalamine in colitis inhibit phosphoinositide 3-kinase signaling in progenitor cells. Inflamm Bowel Dis. 2013 Sep;19(10):2051-60. PMID: 23867870.

 

Baan B, Dihal AA, Hoff E, et al. 5-Aminosalicylic acid inhibits cell cycle progression in a phospholipase D dependent manner in colorectal cancer. Gut. 2012 Dec;61(12):1708-15. PMID: 22187071.

" Xi Not dangerous goods.

LKT A5035 5-Aminosalicylic Acid 100 g 271.7 Salicylic acid derivative; PPARγ agonist, potential COX-1/2 inhibitor. 5-amino-2-hydroxybenzoic acid 5-ASA; Mesalamine; Asacol; Salofalk; 5-amino-2- hydroxybenzoic acid 89-57-6 ≥98% 153.14 C7H7NO3 C1=CC(=C(C=C1N)C(=O)O)O Ambient Ambient "Poh J, Knowles S. Safety of 5-Aminosalicylic Acid Derivatives in Patients with Sensitivity to Acetylsalicylic Acid and Nonsteroidal Anti-inflammatory Drugs. Can J Hosp Pharm. 2014 Jan;67(1):35-8. PMID: 24634525.

 

Managlia E, Katzman RB, Brown JB, et al. Antioxidant properties of mesalamine in colitis inhibit phosphoinositide 3-kinase signaling in progenitor cells. Inflamm Bowel Dis. 2013 Sep;19(10):2051-60. PMID: 23867870.

 

Baan B, Dihal AA, Hoff E, et al. 5-Aminosalicylic acid inhibits cell cycle progression in a phospholipase D dependent manner in colorectal cancer. Gut. 2012 Dec;61(12):1708-15. PMID: 22187071.

" Xi Not dangerous goods.

LKT A5037 Amiodarone Hydrochloride 1 g 57.8 Voltage-gated Na+, Ca2+, K+ channel blocker, α/β-adrenergic antagonist, FIASMA. (2-Butyl-3-benzofuranyl)[4-[2-(diethylamino)ethoxy]-3,5-diiodophenyl]methanone hydrochloride "Amiodar; Ancaron; Cordarone; Ortacrone; Tachydaron; Trangorex

 

" 19774-82-4 ≥98% 681.78 C25H29I2NO3 HCl CCCCC1=C(C2=CC=CC=C2O1)C(=O)C3=CC(=C(C(=C3)I)OCCN(CC)CC)I.Cl Ambient 4°C Soluble in methanol, chloroform, and methylene chloride. Slightly soluble in acetone and dioxane. Sparingly soluble in isopropanol. "Zoerner F, Semenas E. Resuscitation with amiodarone increases survival after hemorrhage and ventricular fibrillation in pigs. J Trauma Acute Care Surg. 2014 Jun;76(6):1402-8. PMID: 24854308.

 

Gehring G, Rohrmann K, Atenchong N, et al. The clinically approved drugs amiodarone, dronedarone and verapamil inhibit filovirus cell entry. J Antimicrob Chemother. 2014 Apr 7. [Epub ahead of print]. PMID: 24710028.

 

Cheng YL, Lan KH, Lee WP, et al. Amiodarone inhibits the entry and assembly steps of hepatitis C virus life cycle. Clin Sci (Lond). 2013 Nov;125(9):439-48. PMID: 23659500.

" Xn Not dangerous goods.

LKT A5037 Amiodarone Hydrochloride 5 g 196.8 Voltage-gated Na+, Ca2+, K+ channel blocker, α/β-adrenergic antagonist, FIASMA. (2-Butyl-3-benzofuranyl)[4-[2-(diethylamino)ethoxy]-3,5-diiodophenyl]methanone hydrochloride "Amiodar; Ancaron; Cordarone; Ortacrone; Tachydaron; Trangorex

 

" 19774-82-4 ≥98% 681.78 C25H29I2NO3 HCl CCCCC1=C(C2=CC=CC=C2O1)C(=O)C3=CC(=C(C(=C3)I)OCCN(CC)CC)I.Cl Ambient 4°C Soluble in methanol, chloroform, and methylene chloride. Slightly soluble in acetone and dioxane. Sparingly soluble in isopropanol. "Zoerner F, Semenas E. Resuscitation with amiodarone increases survival after hemorrhage and ventricular fibrillation in pigs. J Trauma Acute Care Surg. 2014 Jun;76(6):1402-8. PMID: 24854308.

 

Gehring G, Rohrmann K, Atenchong N, et al. The clinically approved drugs amiodarone, dronedarone and verapamil inhibit filovirus cell entry. J Antimicrob Chemother. 2014 Apr 7. [Epub ahead of print]. PMID: 24710028.

 

Cheng YL, Lan KH, Lee WP, et al. Amiodarone inhibits the entry and assembly steps of hepatitis C virus life cycle. Clin Sci (Lond). 2013 Nov;125(9):439-48. PMID: 23659500.

" Xn Not dangerous goods.

LKT A5037 Amiodarone Hydrochloride 10 g 323.5 Voltage-gated Na+, Ca2+, K+ channel blocker, α/β-adrenergic antagonist, FIASMA. (2-Butyl-3-benzofuranyl)[4-[2-(diethylamino)ethoxy]-3,5-diiodophenyl]methanone hydrochloride "Amiodar; Ancaron; Cordarone; Ortacrone; Tachydaron; Trangorex

 

" 19774-82-4 ≥98% 681.78 C25H29I2NO3 HCl CCCCC1=C(C2=CC=CC=C2O1)C(=O)C3=CC(=C(C(=C3)I)OCCN(CC)CC)I.Cl Ambient 4°C Soluble in methanol, chloroform, and methylene chloride. Slightly soluble in acetone and dioxane. Sparingly soluble in isopropanol. "Zoerner F, Semenas E. Resuscitation with amiodarone increases survival after hemorrhage and ventricular fibrillation in pigs. J Trauma Acute Care Surg. 2014 Jun;76(6):1402-8. PMID: 24854308.

 

Gehring G, Rohrmann K, Atenchong N, et al. The clinically approved drugs amiodarone, dronedarone and verapamil inhibit filovirus cell entry. J Antimicrob Chemother. 2014 Apr 7. [Epub ahead of print]. PMID: 24710028.

 

Cheng YL, Lan KH, Lee WP, et al. Amiodarone inhibits the entry and assembly steps of hepatitis C virus life cycle. Clin Sci (Lond). 2013 Nov;125(9):439-48. PMID: 23659500.

" Xn Not dangerous goods.

LKT A5039 Amitraz 5 g 61.1 Insecticide; α-adrenergic agonist, MAO inhibitor. N'-(2,4-Dimethylphenyl)-N-[[(2,4-dimethylphenyl)imino]methyl]-N-methylmethanimidamide Aludex; Mitaban; Mitac; Taktic; Topline 33089-61-1 ≥97% 293.41 C19H23N3 CC1=CC(=C(C=C1)N=CN(C)C=NC2=C(C=C(C=C2)C)C)C Ambient 4°C Insoluble in water. Soluble in xylene and acetone. "Chen AC, He H, Davey RB. Mutations in a putative octopamine receptor gene in amitraz-resistant cattle ticks. Vet Parasitol. 2007 Sep 30;148(3-4):379-83. PMID: 17662534.

 

Chen TH, Hsu WH. Inhibition of insulin release by a formamidine pesticide amitraz and its metabolites in a rat beta-cell line: an action mediated by alpha-2 adrenoceptors, a GTP-binding protein and a decrease in cyclic AMP. J Pharmacol Exp Ther. 1994 Dec;271(3):1240-5. PMID: 7527851.

 

Costa LG, Olibet G, Murphy SD. Alpha 2-adrenoceptors as a target for formamidine pesticides: in vitro and in vivo studies in mice. Toxicol Appl Pharmacol. 1988 Apr;93(2):319-28. PMID: 2833825.

" Xn, N Not dangerous goods.

LKT A5039 Amitraz 25 g 136 Insecticide; α-adrenergic agonist, MAO inhibitor. N'-(2,4-Dimethylphenyl)-N-[[(2,4-dimethylphenyl)imino]methyl]-N-methylmethanimidamide Aludex; Mitaban; Mitac; Taktic; Topline 33089-61-1 ≥97% 293.41 C19H23N3 CC1=CC(=C(C=C1)N=CN(C)C=NC2=C(C=C(C=C2)C)C)C Ambient 4°C Insoluble in water. Soluble in xylene and acetone. "Chen AC, He H, Davey RB. Mutations in a putative octopamine receptor gene in amitraz-resistant cattle ticks. Vet Parasitol. 2007 Sep 30;148(3-4):379-83. PMID: 17662534.

 

Chen TH, Hsu WH. Inhibition of insulin release by a formamidine pesticide amitraz and its metabolites in a rat beta-cell line: an action mediated by alpha-2 adrenoceptors, a GTP-binding protein and a decrease in cyclic AMP. J Pharmacol Exp Ther. 1994 Dec;271(3):1240-5. PMID: 7527851.

 

Costa LG, Olibet G, Murphy SD. Alpha 2-adrenoceptors as a target for formamidine pesticides: in vitro and in vivo studies in mice. Toxicol Appl Pharmacol. 1988 Apr;93(2):319-28. PMID: 2833825.

" Xn, N Not dangerous goods.

LKT A5039 Amitraz 100 g 407.7 Insecticide; α-adrenergic agonist, MAO inhibitor. N'-(2,4-Dimethylphenyl)-N-[[(2,4-dimethylphenyl)imino]methyl]-N-methylmethanimidamide Aludex; Mitaban; Mitac; Taktic; Topline 33089-61-1 ≥97% 293.41 C19H23N3 CC1=CC(=C(C=C1)N=CN(C)C=NC2=C(C=C(C=C2)C)C)C Ambient 4°C Insoluble in water. Soluble in xylene and acetone. "Chen AC, He H, Davey RB. Mutations in a putative octopamine receptor gene in amitraz-resistant cattle ticks. Vet Parasitol. 2007 Sep 30;148(3-4):379-83. PMID: 17662534.

 

Chen TH, Hsu WH. Inhibition of insulin release by a formamidine pesticide amitraz and its metabolites in a rat beta-cell line: an action mediated by alpha-2 adrenoceptors, a GTP-binding protein and a decrease in cyclic AMP. J Pharmacol Exp Ther. 1994 Dec;271(3):1240-5. PMID: 7527851.

 

Costa LG, Olibet G, Murphy SD. Alpha 2-adrenoceptors as a target for formamidine pesticides: in vitro and in vivo studies in mice. Toxicol Appl Pharmacol. 1988 Apr;93(2):319-28. PMID: 2833825.

" Xn, N Not dangerous goods.

LKT A5044 Amlodipine Besylate 1 g 67.9 Dihydropyridine, FIASMA; L-type Ca2+ channel blocker. 2-[(2-Aminoethoxy)methyl]-4-(2-chlorophenyl)-1,4- dihydro-6-methyl-3,5-pyridinedicarboxylic acid 3-ethyl 5-methyl ester benzenesulfonate Amlodipine Benzenesulfonate; Amlor; Istin; Monopina; Norvasc 111470-99-6 ≥98% 567.06 C20H25ClN2O5C6H5SO3H CCOC(=O)C1=C(NC(=C(C1C2=CC=CC=C2Cl)C(=O)OC)C)COCCN.C1=CC=C(C=C1)S(=O)(=O)O Ambient Ambient Slightly soluble in water. Sparingly soluble in ethanol. soluble in DMSO(113mg/ml) "Chen JL, Shang QH, Hu W, et al. Role of TGF-β1/Smads pathway in carotid artery remodeling in renovascular hypertensive rats and prevention by Enalapril and Amlodipine. J Geriatr Cardiol. 2012 Jun;9(2):185-91. PMID: 22916067.

 

Kornhuber J, Tripal P, Reichel M, et al. Functional Inhibitors of Acid Sphingomyelinase (FIASMAs): a novel pharmacological group of drugs with broad clinical applications. Cell Physiol Biochem. 2010;26(1):9-20. PMID: 20502000.

 

Wang JG. A combined role of calcium channel blockers and angiotensin receptor blockers in stroke prevention. Vasc Health Risk Manag. 2009;5:593-605. PMID: 19688100.

" Xn Not dangerous goods.

LKT A5044 Amlodipine Besylate 5 g 271.7 Dihydropyridine, FIASMA; L-type Ca2+ channel blocker. 2-[(2-Aminoethoxy)methyl]-4-(2-chlorophenyl)-1,4- dihydro-6-methyl-3,5-pyridinedicarboxylic acid 3-ethyl 5-methyl ester benzenesulfonate Amlodipine Benzenesulfonate; Amlor; Istin; Monopina; Norvasc 111470-99-6 ≥98% 567.06 C20H25ClN2O5C6H5SO3H CCOC(=O)C1=C(NC(=C(C1C2=CC=CC=C2Cl)C(=O)OC)C)COCCN.C1=CC=C(C=C1)S(=O)(=O)O Ambient Ambient Slightly soluble in water. Sparingly soluble in ethanol. soluble in DMSO(113mg/ml) "Chen JL, Shang QH, Hu W, et al. Role of TGF-β1/Smads pathway in carotid artery remodeling in renovascular hypertensive rats and prevention by Enalapril and Amlodipine. J Geriatr Cardiol. 2012 Jun;9(2):185-91. PMID: 22916067.

 

Kornhuber J, Tripal P, Reichel M, et al. Functional Inhibitors of Acid Sphingomyelinase (FIASMAs): a novel pharmacological group of drugs with broad clinical applications. Cell Physiol Biochem. 2010;26(1):9-20. PMID: 20502000.

 

Wang JG. A combined role of calcium channel blockers and angiotensin receptor blockers in stroke prevention. Vasc Health Risk Manag. 2009;5:593-605. PMID: 19688100.

" Xn Not dangerous goods.

LKT A5044 Amlodipine Besylate 10 g 364.2 Dihydropyridine, FIASMA; L-type Ca2+ channel blocker. 2-[(2-Aminoethoxy)methyl]-4-(2-chlorophenyl)-1,4- dihydro-6-methyl-3,5-pyridinedicarboxylic acid 3-ethyl 5-methyl ester benzenesulfonate Amlodipine Benzenesulfonate; Amlor; Istin; Monopina; Norvasc 111470-99-6 ≥98% 567.06 C20H25ClN2O5C6H5SO3H CCOC(=O)C1=C(NC(=C(C1C2=CC=CC=C2Cl)C(=O)OC)C)COCCN.C1=CC=C(C=C1)S(=O)(=O)O Ambient Ambient Slightly soluble in water. Sparingly soluble in ethanol. soluble in DMSO(113mg/ml) "Chen JL, Shang QH, Hu W, et al. Role of TGF-β1/Smads pathway in carotid artery remodeling in renovascular hypertensive rats and prevention by Enalapril and Amlodipine. J Geriatr Cardiol. 2012 Jun;9(2):185-91. PMID: 22916067.

 

Kornhuber J, Tripal P, Reichel M, et al. Functional Inhibitors of Acid Sphingomyelinase (FIASMAs): a novel pharmacological group of drugs with broad clinical applications. Cell Physiol Biochem. 2010;26(1):9-20. PMID: 20502000.

 

Wang JG. A combined role of calcium channel blockers and angiotensin receptor blockers in stroke prevention. Vasc Health Risk Manag. 2009;5:593-605. PMID: 19688100.

" Xn Not dangerous goods.

LKT A5045 Amlodipine 1 g 67.9 Dihydropyridine, FIASMA; L-type Ca2+ channel blocker. 2-[(2-Aminoethoxy)methyl]-4-(2-chlorophenyl)-1,4- dihydro-6-methyl-3,5-pyridinedicarboxylic acid 3-ethyl 5-methyl ester UK-48340 88150-42-9 ≥98% 408.88 C20H25ClN2O5 CCOC(=O)C1=C(NC(=C(C1C2=CC=CC=C2Cl)C(=O)OC)C)COCCN Ambient Ambient Soluble in methanol, ethanol (82mg/mL)choroform and DMSO (82mg/mL). "Chen JL, Shang QH, Hu W, et al. Role of TGF-β1/Smads pathway in carotid artery remodeling in renovascular hypertensive rats and prevention by Enalapril and Amlodipine. J Geriatr Cardiol. 2012 Jun;9(2):185-91. PMID: 22916067.

 

Kornhuber J, Tripal P, Reichel M, et al. Functional Inhibitors of Acid Sphingomyelinase (FIASMAs): a novel pharmacological group of drugs with broad clinical applications. Cell Physiol Biochem. 2010;26(1):9-20. PMID: 20502000.

 

Wang JG. A combined role of calcium channel blockers and angiotensin receptor blockers in stroke prevention. Vasc Health Risk Manag. 2009;5:593-605. PMID: 19688100.

 

Fan YY, Kohno M, Nakano D, et al. Cilnidipine suppresses podocyte injury and proteinuria in metabolic syndrome rats: possible involvement of N-type calcium channel in podocyte. J Hypertens. 2010 May;28(5):1034-1043. PMID: 20411599.

" Xn Not dangerous goods.

LKT A5045 Amlodipine 5 g 244.5 Dihydropyridine, FIASMA; L-type Ca2+ channel blocker. 2-[(2-Aminoethoxy)methyl]-4-(2-chlorophenyl)-1,4- dihydro-6-methyl-3,5-pyridinedicarboxylic acid 3-ethyl 5-methyl ester UK-48340 88150-42-9 ≥98% 408.88 C20H25ClN2O5 CCOC(=O)C1=C(NC(=C(C1C2=CC=CC=C2Cl)C(=O)OC)C)COCCN Ambient Ambient Soluble in methanol, ethanol (82mg/mL)choroform and DMSO (82mg/mL). "Chen JL, Shang QH, Hu W, et al. Role of TGF-β1/Smads pathway in carotid artery remodeling in renovascular hypertensive rats and prevention by Enalapril and Amlodipine. J Geriatr Cardiol. 2012 Jun;9(2):185-91. PMID: 22916067.

 

Kornhuber J, Tripal P, Reichel M, et al. Functional Inhibitors of Acid Sphingomyelinase (FIASMAs): a novel pharmacological group of drugs with broad clinical applications. Cell Physiol Biochem. 2010;26(1):9-20. PMID: 20502000.

 

Wang JG. A combined role of calcium channel blockers and angiotensin receptor blockers in stroke prevention. Vasc Health Risk Manag. 2009;5:593-605. PMID: 19688100.

 

Fan YY, Kohno M, Nakano D, et al. Cilnidipine suppresses podocyte injury and proteinuria in metabolic syndrome rats: possible involvement of N-type calcium channel in podocyte. J Hypertens. 2010 May;28(5):1034-1043. PMID: 20411599.

" Xn Not dangerous goods.

LKT A5045 Amlodipine 10 g 305.9 Dihydropyridine, FIASMA; L-type Ca2+ channel blocker. 2-[(2-Aminoethoxy)methyl]-4-(2-chlorophenyl)-1,4- dihydro-6-methyl-3,5-pyridinedicarboxylic acid 3-ethyl 5-methyl ester UK-48340 88150-42-9 ≥98% 408.88 C20H25ClN2O5 CCOC(=O)C1=C(NC(=C(C1C2=CC=CC=C2Cl)C(=O)OC)C)COCCN Ambient Ambient Soluble in methanol, ethanol (82mg/mL)choroform and DMSO (82mg/mL). "Chen JL, Shang QH, Hu W, et al. Role of TGF-β1/Smads pathway in carotid artery remodeling in renovascular hypertensive rats and prevention by Enalapril and Amlodipine. J Geriatr Cardiol. 2012 Jun;9(2):185-91. PMID: 22916067.

 

Kornhuber J, Tripal P, Reichel M, et al. Functional Inhibitors of Acid Sphingomyelinase (FIASMAs): a novel pharmacological group of drugs with broad clinical applications. Cell Physiol Biochem. 2010;26(1):9-20. PMID: 20502000.

 

Wang JG. A combined role of calcium channel blockers and angiotensin receptor blockers in stroke prevention. Vasc Health Risk Manag. 2009;5:593-605. PMID: 19688100.

 

Fan YY, Kohno M, Nakano D, et al. Cilnidipine suppresses podocyte injury and proteinuria in metabolic syndrome rats: possible involvement of N-type calcium channel in podocyte. J Hypertens. 2010 May;28(5):1034-1043. PMID: 20411599.

" Xn Not dangerous goods.

LKT A5056 Amorolfine Hydrochloride 100 mg 75 14α-demethylase inhibitor. (2S,6R)-2,6-dimethyl-4-[2-methyl-3-[4-(2-methylbutan-2-yl)phenyl]propyl]morpholine hydrochloride 78613-38-4 ≥98.5% 353.97 C21H35NO HCl CCC(C)(C)C1=CC=C(C=C1)CC(C)CN2CC(OC(C2)C)C.Cl Ambient Ambient Slightly soluble in water, less soluble in HCl solution "Ghelardi E, Celandroni F, Gueye SA, et al. Potential of Ergosterol Synthesis Inhibitors To Cause Resistance or Cross-Resistance in Trichophyton rubrum. Antimicrob Agents Chemother. 2014 May;58(5):2825-9. PMID: 24614379.

 

Hau CS, Kanda N, Watanabe S. Suppressive effects of antimycotics on thymic stromal lymphopoietin production in human keratinocytes. J Dermatol Sci. 2013 Sep;71(3):174-83. PMID: 23688403.

" "UN number: 3077     Class: 9     Packing Group: III

Proper shipping name: Environmentally hazardous substance, solid, n.o.s. (Amorolfine Hydrochloride)"

LKT A5056 Amorolfine Hydrochloride 250 mg 140.7 14α-demethylase inhibitor. (2S,6R)-2,6-dimethyl-4-[2-methyl-3-[4-(2-methylbutan-2-yl)phenyl]propyl]morpholine hydrochloride 78613-38-4 ≥98.5% 353.97 C21H35NO HCl CCC(C)(C)C1=CC=C(C=C1)CC(C)CN2CC(OC(C2)C)C.Cl Ambient Ambient Slightly soluble in water, less soluble in HCl solution "Ghelardi E, Celandroni F, Gueye SA, et al. Potential of Ergosterol Synthesis Inhibitors To Cause Resistance or Cross-Resistance in Trichophyton rubrum. Antimicrob Agents Chemother. 2014 May;58(5):2825-9. PMID: 24614379.

 

Hau CS, Kanda N, Watanabe S. Suppressive effects of antimycotics on thymic stromal lymphopoietin production in human keratinocytes. J Dermatol Sci. 2013 Sep;71(3):174-83. PMID: 23688403.

" "UN number: 3077     Class: 9     Packing Group: III

Proper shipping name: Environmentally hazardous substance, solid, n.o.s. (Amorolfine Hydrochloride)"

LKT A5056 Amorolfine Hydrochloride 1 g 300.1 14α-demethylase inhibitor. (2S,6R)-2,6-dimethyl-4-[2-methyl-3-[4-(2-methylbutan-2-yl)phenyl]propyl]morpholine hydrochloride 78613-38-4 ≥98.5% 353.97 C21H35NO HCl CCC(C)(C)C1=CC=C(C=C1)CC(C)CN2CC(OC(C2)C)C.Cl Ambient Ambient Slightly soluble in water, less soluble in HCl solution "Ghelardi E, Celandroni F, Gueye SA, et al. Potential of Ergosterol Synthesis Inhibitors To Cause Resistance or Cross-Resistance in Trichophyton rubrum. Antimicrob Agents Chemother. 2014 May;58(5):2825-9. PMID: 24614379.

 

Hau CS, Kanda N, Watanabe S. Suppressive effects of antimycotics on thymic stromal lymphopoietin production in human keratinocytes. J Dermatol Sci. 2013 Sep;71(3):174-83. PMID: 23688403.

" "UN number: 3077     Class: 9     Packing Group: III

Proper shipping name: Environmentally hazardous substance, solid, n.o.s. (Amorolfine Hydrochloride)"

LKT A5057 Amoxicillin 5 g 52.6 β-lactam; penicillin binding protein inhibitor. "(2S,5R,6R)-6-[[(2R)-amino(4-hydroxyphenyl)- acetyl]amino]-3,3-dimethyl-7-oxo-4-Thia-1-azabicyclo-[3.2.0]heptane-2-carboxylic acid 

 

" Amoxycillin; Amolin; Amopenixin; Helvamox; Moxal; Pasetocin; AMPC 26787-78-0 ≥98% 365.41 C16H19N3O5S CC1(C(N2C(S1)C(C2=O)NC(=O)C(C3=CC=C(C=C3)O)N)C(=O)O)C Very hygroscopic. Ambient Ambient Soluble in water, DMSO, ethanol. "Astasov-Frauenhoffer M, Braissant O, Hauser-Gerspach I, et al. Microcalorimetric determination of the effects of amoxicillin, metronidazole, and their combination on in vitro biofilm. J Periodontol. 2014 Feb;85(2):349-57. PMID: 23594193.

 

Martin SI, Kaye KM. Beta-lactam antibiotics: newer formulations and newer agents. Infect Dis Clin North Am. 2004 Sep;18(3):603-19. PMID: 15308278.

 

Weber DJ, Tolkoff-Rubin NE, Rubin RH. Amoxicillin and potassium clavulanate: an antibiotic combination. Mechanism of action, pharmacokinetics, antimicrobial spectrum, clinical efficacy and adverse effects. Pharmacotherapy. 1984 May-Jun;4(3):122-36. PMID: 6739312.

" Not dangerous goods.

LKT A5057 Amoxicillin 25 g 94.4 β-lactam; penicillin binding protein inhibitor. "(2S,5R,6R)-6-[[(2R)-amino(4-hydroxyphenyl)- acetyl]amino]-3,3-dimethyl-7-oxo-4-Thia-1-azabicyclo-[3.2.0]heptane-2-carboxylic acid 

 

" Amoxycillin; Amolin; Amopenixin; Helvamox; Moxal; Pasetocin; AMPC 26787-78-0 ≥98% 365.41 C16H19N3O5S CC1(C(N2C(S1)C(C2=O)NC(=O)C(C3=CC=C(C=C3)O)N)C(=O)O)C Very hygroscopic. Ambient Ambient Soluble in water, DMSO, ethanol. "Astasov-Frauenhoffer M, Braissant O, Hauser-Gerspach I, et al. Microcalorimetric determination of the effects of amoxicillin, metronidazole, and their combination on in vitro biofilm. J Periodontol. 2014 Feb;85(2):349-57. PMID: 23594193.

 

Martin SI, Kaye KM. Beta-lactam antibiotics: newer formulations and newer agents. Infect Dis Clin North Am. 2004 Sep;18(3):603-19. PMID: 15308278.

 

Weber DJ, Tolkoff-Rubin NE, Rubin RH. Amoxicillin and potassium clavulanate: an antibiotic combination. Mechanism of action, pharmacokinetics, antimicrobial spectrum, clinical efficacy and adverse effects. Pharmacotherapy. 1984 May-Jun;4(3):122-36. PMID: 6739312.

" Not dangerous goods.

LKT A5057 Amoxicillin 100 g 283.5 β-lactam; penicillin binding protein inhibitor. "(2S,5R,6R)-6-[[(2R)-amino(4-hydroxyphenyl)- acetyl]amino]-3,3-dimethyl-7-oxo-4-Thia-1-azabicyclo-[3.2.0]heptane-2-carboxylic acid 

 

" Amoxycillin; Amolin; Amopenixin; Helvamox; Moxal; Pasetocin; AMPC 26787-78-0 ≥98% 365.41 C16H19N3O5S CC1(C(N2C(S1)C(C2=O)NC(=O)C(C3=CC=C(C=C3)O)N)C(=O)O)C Very hygroscopic. Ambient Ambient Soluble in water, DMSO, ethanol. "Astasov-Frauenhoffer M, Braissant O, Hauser-Gerspach I, et al. Microcalorimetric determination of the effects of amoxicillin, metronidazole, and their combination on in vitro biofilm. J Periodontol. 2014 Feb;85(2):349-57. PMID: 23594193.

 

Martin SI, Kaye KM. Beta-lactam antibiotics: newer formulations and newer agents. Infect Dis Clin North Am. 2004 Sep;18(3):603-19. PMID: 15308278.

 

Weber DJ, Tolkoff-Rubin NE, Rubin RH. Amoxicillin and potassium clavulanate: an antibiotic combination. Mechanism of action, pharmacokinetics, antimicrobial spectrum, clinical efficacy and adverse effects. Pharmacotherapy. 1984 May-Jun;4(3):122-36. PMID: 6739312.

" Not dangerous goods.

LKT A5059 Amoxapine 250 mg 81.6 5-HT2/3/6/7, D2/3/4, histamine H1, α1-adrenergic antagonist, SERT and NET inhibitor, hERG K+ channel blocker. 8-chloro-6-piperazin-1-ylbenzo[b][1,4]benzoxazepine 14028-44-5 ≥98% 313.78 C17H16ClN3O C1CN(CCN1)C2=NC3=CC=CC=C3OC4=C2C=C(C=C4)Cl Ambient Ambient "Ahmad S, Hughes MA, Yeh LA, et al. Potential repurposing of known drugs as potent bacterial β-glucuronidase inhibitors. J Biomol Screen. 2012 Aug;17(7):957-65. PMID: 22535688.

 

Yang G, Zhou MH, Ren Z, et al. Amoxapine inhibits delayed outward rectifier K(+) currents in cerebellar granule cells via dopamine receptor and protein kinase A activation. Cell Physiol Biochem. 2011;28(1):163-74. PMID: 21865859.

 

Obers S, Staudacher I, Ficker E, et al. Multiple mechanisms of hERG liability: K+ current inhibition, disruption of protein trafficking, and apoptosis induced by amoxapine. Naunyn Schmiedebergs Arch Pharmacol. 2010 May;381(5):385-400. PMID: 20229012.

 

Chaudhry IB, Husain N, Khan S, et al. Amoxapine as an antipsychotic: comparative study versus haloperidol. J Clin Psychopharmacol. 2007 Dec;27(6):575-81. PMID: 18004123.

 

Takebayashi M, Kagaya A, Inagaki M, et al. Effects of antidepressants on gamma-aminobutyric acid- and N-methyl-D-aspartate-induced intracellular Ca(2+) concentration increases in primary cultured rat cortical neurons. Neuropsychobiology. 2000;42(3):120-6. PMID: 11015029.

 

Roth BL, Craigo SC, Choudhary MS, et al. Binding of typical and atypical antipsychotic agents to 5-hydroxytryptamine-6 and 5-hydroxytryptamine-7 receptors. J Pharmacol Exp Ther. 1994 Mar;268(3):1403-10. PMID: 7908055.

 

Gozlan H, Saddiki-Traki F, Merahi N, et al. Preclinical pharmacology of amoxapine and amitriptyline. Implications of serotoninergic and opiodergic systems in their central effect in rats. Encephale. 1991 Dec;17 Spec No 3:415-22. PMID: 1666997.

 

Hamon M, Gozlan H, Bourgoin S, et al. Opioid receptors and neuropeptides in the CNS in rats treated chronically with amoxapine or amitriptyline. Neuropharmacology. 1987 Jun;26(6):531-9. PMID: 3037421.

" Xn Not dangerous goods.

LKT A5059 Amoxapine 1 g 237.8 5-HT2/3/6/7, D2/3/4, histamine H1, α1-adrenergic antagonist, SERT and NET inhibitor, hERG K+ channel blocker. 8-chloro-6-piperazin-1-ylbenzo[b][1,4]benzoxazepine 14028-44-5 ≥98% 313.78 C17H16ClN3O C1CN(CCN1)C2=NC3=CC=CC=C3OC4=C2C=C(C=C4)Cl Ambient Ambient "Ahmad S, Hughes MA, Yeh LA, et al. Potential repurposing of known drugs as potent bacterial β-glucuronidase inhibitors. J Biomol Screen. 2012 Aug;17(7):957-65. PMID: 22535688.

 

Yang G, Zhou MH, Ren Z, et al. Amoxapine inhibits delayed outward rectifier K(+) currents in cerebellar granule cells via dopamine receptor and protein kinase A activation. Cell Physiol Biochem. 2011;28(1):163-74. PMID: 21865859.

 

Obers S, Staudacher I, Ficker E, et al. Multiple mechanisms of hERG liability: K+ current inhibition, disruption of protein trafficking, and apoptosis induced by amoxapine. Naunyn Schmiedebergs Arch Pharmacol. 2010 May;381(5):385-400. PMID: 20229012.

 

Chaudhry IB, Husain N, Khan S, et al. Amoxapine as an antipsychotic: comparative study versus haloperidol. J Clin Psychopharmacol. 2007 Dec;27(6):575-81. PMID: 18004123.

 

Takebayashi M, Kagaya A, Inagaki M, et al. Effects of antidepressants on gamma-aminobutyric acid- and N-methyl-D-aspartate-induced intracellular Ca(2+) concentration increases in primary cultured rat cortical neurons. Neuropsychobiology. 2000;42(3):120-6. PMID: 11015029.

 

Roth BL, Craigo SC, Choudhary MS, et al. Binding of typical and atypical antipsychotic agents to 5-hydroxytryptamine-6 and 5-hydroxytryptamine-7 receptors. J Pharmacol Exp Ther. 1994 Mar;268(3):1403-10. PMID: 7908055.

 

Gozlan H, Saddiki-Traki F, Merahi N, et al. Preclinical pharmacology of amoxapine and amitriptyline. Implications of serotoninergic and opiodergic systems in their central effect in rats. Encephale. 1991 Dec;17 Spec No 3:415-22. PMID: 1666997.

 

Hamon M, Gozlan H, Bourgoin S, et al. Opioid receptors and neuropeptides in the CNS in rats treated chronically with amoxapine or amitriptyline. Neuropharmacology. 1987 Jun;26(6):531-9. PMID: 3037421.

" Xn Not dangerous goods.

LKT A5059 Amoxapine 5 g 441.6 5-HT2/3/6/7, D2/3/4, histamine H1, α1-adrenergic antagonist, SERT and NET inhibitor, hERG K+ channel blocker. 8-chloro-6-piperazin-1-ylbenzo[b][1,4]benzoxazepine 14028-44-5 ≥98% 313.78 C17H16ClN3O C1CN(CCN1)C2=NC3=CC=CC=C3OC4=C2C=C(C=C4)Cl Ambient Ambient "Ahmad S, Hughes MA, Yeh LA, et al. Potential repurposing of known drugs as potent bacterial β-glucuronidase inhibitors. J Biomol Screen. 2012 Aug;17(7):957-65. PMID: 22535688.

 

Yang G, Zhou MH, Ren Z, et al. Amoxapine inhibits delayed outward rectifier K(+) currents in cerebellar granule cells via dopamine receptor and protein kinase A activation. Cell Physiol Biochem. 2011;28(1):163-74. PMID: 21865859.

 

Obers S, Staudacher I, Ficker E, et al. Multiple mechanisms of hERG liability: K+ current inhibition, disruption of protein trafficking, and apoptosis induced by amoxapine. Naunyn Schmiedebergs Arch Pharmacol. 2010 May;381(5):385-400. PMID: 20229012.

 

Chaudhry IB, Husain N, Khan S, et al. Amoxapine as an antipsychotic: comparative study versus haloperidol. J Clin Psychopharmacol. 2007 Dec;27(6):575-81. PMID: 18004123.

 

Takebayashi M, Kagaya A, Inagaki M, et al. Effects of antidepressants on gamma-aminobutyric acid- and N-methyl-D-aspartate-induced intracellular Ca(2+) concentration increases in primary cultured rat cortical neurons. Neuropsychobiology. 2000;42(3):120-6. PMID: 11015029.

 

Roth BL, Craigo SC, Choudhary MS, et al. Binding of typical and atypical antipsychotic agents to 5-hydroxytryptamine-6 and 5-hydroxytryptamine-7 receptors. J Pharmacol Exp Ther. 1994 Mar;268(3):1403-10. PMID: 7908055.

 

Gozlan H, Saddiki-Traki F, Merahi N, et al. Preclinical pharmacology of amoxapine and amitriptyline. Implications of serotoninergic and opiodergic systems in their central effect in rats. Encephale. 1991 Dec;17 Spec No 3:415-22. PMID: 1666997.

 

Hamon M, Gozlan H, Bourgoin S, et al. Opioid receptors and neuropeptides in the CNS in rats treated chronically with amoxapine or amitriptyline. Neuropharmacology. 1987 Jun;26(6):531-9. PMID: 3037421.

" Xn Not dangerous goods.

LKT A5072 Amsacrine 10 mg 187.4 Acridine derivative, DNA intercalator; topoisomerase II inhibitor, hERG K+ channel blocker. 4-(9-Acridinylamino)-N-(methanesulfonyl)-m-anisidine hydrochloride, m-AMSA 51264-14-3 ≥98% 393.46 C21H19N3O3S COC1=C(C=CC(=C1)NS(=O)(=O)C)NC2=C3C=CC=CC3=NC4=CC=CC=C42 Ambient Ambient "Liu WH, Chen YJ, Chien JH, et al. Amsacrine suppresses matrix metalloproteinase-2 (MMP-2)/MMP-9 expression in human leukemia cells. J Cell Physiol. 2013 Oct 7. Epub ahead of print. PMID: 24122234.

 

Jangir DK, Dey SK, Kundu S, et al. Assessment of amsacrine binding with DNA using UV-visible, circular dichroism and Raman spectroscopic techniques. J Photochem Photobiol B. 2012 Sep 3;114:38-43. PMID: 22677564.

 

Thomas D, Hammerling BC, Wu K, et al. Inhibition of cardiac HERG currents by the DNA topoisomerase II inhibitor amsacrine: mode of action. Br J Pharmacol. 2004 Jun;142(3):485-94. PMID: 15148258.

 

Robinson MJ, Osheroff N. Stabilization of the topoisomerase II-DNA cleavage complex by antineoplastic drugs: inhibition of enzyme-mediated DNA religation by 4'-(9-acridinylamino)methanesulfon-m-anisidide. Biochemistry. 1990 Mar 13;29(10):2511-5. PMID: 2159323.

" "UN number: 2811     Class: 6.1     Packing Group: III

Proper shipping name: Toxic solid, organic, n.o.s. (Amsacrine)"

LKT A5072 Amsacrine 50 mg 797 Acridine derivative, DNA intercalator; topoisomerase II inhibitor, hERG K+ channel blocker. 4-(9-Acridinylamino)-N-(methanesulfonyl)-m-anisidine hydrochloride, m-AMSA 51264-14-3 ≥98% 393.46 C21H19N3O3S COC1=C(C=CC(=C1)NS(=O)(=O)C)NC2=C3C=CC=CC3=NC4=CC=CC=C42 Ambient Ambient "Liu WH, Chen YJ, Chien JH, et al. Amsacrine suppresses matrix metalloproteinase-2 (MMP-2)/MMP-9 expression in human leukemia cells. J Cell Physiol. 2013 Oct 7. Epub ahead of print. PMID: 24122234.

 

Jangir DK, Dey SK, Kundu S, et al. Assessment of amsacrine binding with DNA using UV-visible, circular dichroism and Raman spectroscopic techniques. J Photochem Photobiol B. 2012 Sep 3;114:38-43. PMID: 22677564.

 

Thomas D, Hammerling BC, Wu K, et al. Inhibition of cardiac HERG currents by the DNA topoisomerase II inhibitor amsacrine: mode of action. Br J Pharmacol. 2004 Jun;142(3):485-94. PMID: 15148258.

 

Robinson MJ, Osheroff N. Stabilization of the topoisomerase II-DNA cleavage complex by antineoplastic drugs: inhibition of enzyme-mediated DNA religation by 4'-(9-acridinylamino)methanesulfon-m-anisidide. Biochemistry. 1990 Mar 13;29(10):2511-5. PMID: 2159323.

" "UN number: 2811     Class: 6.1     Packing Group: III

Proper shipping name: Toxic solid, organic, n.o.s. (Amsacrine)"

LKT A5130 Amphotericin B 100 mg 47.6 Polyene, binds ergosterol and induces membrane pore formations. Ampho-Moronal; Fungilin; Fungizone 1397-89-3 ≥87% 924.08 C47H73NO17 CC1C=CC=CC=CC=CC=CC=CC=CC(CC2C(C(CC(O2)(CC(CC(C(CCC(CC(CC(=O)OC(C(C1O)C)C)O)O)O)O)O)O)O)C(=O)O)OC3C(C(C(C(O3)C)O)N)O Protect from light. Ambient -20°C Soluble in DMSO (30-40mg/mL), DMF(2-4mg/mL) or water (pH 2 or 11). "Serhan G, Stack CM, Perrone GG, et al. The polyene antifungals, amphotericin B and nystatin, cause cell death in Saccharomyces cerevisiae by a distinct mechanism to amphibian-derived antimicrobial peptides. Ann Clin Microbiol Antimicrob. 2014 May 12;13:18. PMID: 24884795.

 

Nakagawa Y, Umegawa Y, Takano T, et al. Effect of sterol side chain on ion channel formation by amphotericin B in lipid bilayers. Biochemistry. 2014 May 20;53(19):3088-94. PMID: 24762132.

 

Motoyoshi-Yamashiro A, Tamura M, Moriyama M, et al. Activation of cultured astrocytes by amphotericin B: stimulation of NO and cytokines production and changes in neurotrophic factors production. Neurochem Int. 2013 Aug;63(2):93-100. PMID: 23727061.

" Xi Not dangerous goods.

LKT A5130 Amphotericin B 250 mg 65.3 Polyene, binds ergosterol and induces membrane pore formations. Ampho-Moronal; Fungilin; Fungizone 1397-89-3 ≥87% 924.08 C47H73NO17 CC1C=CC=CC=CC=CC=CC=CC=CC(CC2C(C(CC(O2)(CC(CC(C(CCC(CC(CC(=O)OC(C(C1O)C)C)O)O)O)O)O)O)O)C(=O)O)OC3C(C(C(C(O3)C)O)N)O Protect from light. Ambient -20°C Soluble in DMSO (30-40mg/mL), DMF(2-4mg/mL) or water (pH 2 or 11). "Serhan G, Stack CM, Perrone GG, et al. The polyene antifungals, amphotericin B and nystatin, cause cell death in Saccharomyces cerevisiae by a distinct mechanism to amphibian-derived antimicrobial peptides. Ann Clin Microbiol Antimicrob. 2014 May 12;13:18. PMID: 24884795.

 

Nakagawa Y, Umegawa Y, Takano T, et al. Effect of sterol side chain on ion channel formation by amphotericin B in lipid bilayers. Biochemistry. 2014 May 20;53(19):3088-94. PMID: 24762132.

 

Motoyoshi-Yamashiro A, Tamura M, Moriyama M, et al. Activation of cultured astrocytes by amphotericin B: stimulation of NO and cytokines production and changes in neurotrophic factors production. Neurochem Int. 2013 Aug;63(2):93-100. PMID: 23727061.

" Xi Not dangerous goods.

LKT A5130 Amphotericin B 500 mg 81.6 Polyene, binds ergosterol and induces membrane pore formations. Ampho-Moronal; Fungilin; Fungizone 1397-89-3 ≥87% 924.08 C47H73NO17 CC1C=CC=CC=CC=CC=CC=CC=CC(CC2C(C(CC(O2)(CC(CC(C(CCC(CC(CC(=O)OC(C(C1O)C)C)O)O)O)O)O)O)O)C(=O)O)OC3C(C(C(C(O3)C)O)N)O Protect from light. Ambient -20°C Soluble in DMSO (30-40mg/mL), DMF(2-4mg/mL) or water (pH 2 or 11). "Serhan G, Stack CM, Perrone GG, et al. The polyene antifungals, amphotericin B and nystatin, cause cell death in Saccharomyces cerevisiae by a distinct mechanism to amphibian-derived antimicrobial peptides. Ann Clin Microbiol Antimicrob. 2014 May 12;13:18. PMID: 24884795.

 

Nakagawa Y, Umegawa Y, Takano T, et al. Effect of sterol side chain on ion channel formation by amphotericin B in lipid bilayers. Biochemistry. 2014 May 20;53(19):3088-94. PMID: 24762132.

 

Motoyoshi-Yamashiro A, Tamura M, Moriyama M, et al. Activation of cultured astrocytes by amphotericin B: stimulation of NO and cytokines production and changes in neurotrophic factors production. Neurochem Int. 2013 Aug;63(2):93-100. PMID: 23727061.

" Xi Not dangerous goods.

LKT A5130 Amphotericin B 1 g 251.5 Polyene, binds ergosterol and induces membrane pore formations. Ampho-Moronal; Fungilin; Fungizone 1397-89-3 ≥87% 924.08 C47H73NO17 CC1C=CC=CC=CC=CC=CC=CC=CC(CC2C(C(CC(O2)(CC(CC(C(CCC(CC(CC(=O)OC(C(C1O)C)C)O)O)O)O)O)O)O)C(=O)O)OC3C(C(C(C(O3)C)O)N)O Protect from light. Ambient -20°C Soluble in DMSO (30-40mg/mL), DMF(2-4mg/mL) or water (pH 2 or 11). "Serhan G, Stack CM, Perrone GG, et al. The polyene antifungals, amphotericin B and nystatin, cause cell death in Saccharomyces cerevisiae by a distinct mechanism to amphibian-derived antimicrobial peptides. Ann Clin Microbiol Antimicrob. 2014 May 12;13:18. PMID: 24884795.

 

Nakagawa Y, Umegawa Y, Takano T, et al. Effect of sterol side chain on ion channel formation by amphotericin B in lipid bilayers. Biochemistry. 2014 May 20;53(19):3088-94. PMID: 24762132.

 

Motoyoshi-Yamashiro A, Tamura M, Moriyama M, et al. Activation of cultured astrocytes by amphotericin B: stimulation of NO and cytokines production and changes in neurotrophic factors production. Neurochem Int. 2013 Aug;63(2):93-100. PMID: 23727061.

" Xi Not dangerous goods.

LKT A5132 Amikacin Disulfate 250 mg 40.7 Aminoglycoside; protein translation inhibitor. O-3-Amino-3-deoxy-α-D-glucopyranosyl-(1->6)-O- [6-amino-6-deoxy-α-D-glucopyranosyl-(1->4)]-N1- [(2S)-4-amino-2-hydroxy-1-oxobutyl]-2-deoxy-D- streptamine sulfate Amikacin sulfate; Amikin; Biklin; Lukadin; Mikavir; Novamin; Pierami 39831-55-5 ≥98% 781.76 C22H43N5O13 2H2SO4 C1C(C(C(C(C1NC(=O)C(CCN)O)OC2C(C(C(C(O2)CO)O)N)O)O)OC3C(C(C(C(O3)CN)O)O)O)N.OS(=O)(=O)O.OS(=O)(=O)O In DMSO at +4 for 2 weeks at -80 for 6 months. Ambient Ambient Soluble in water (50mg/mL). Insolulble in acetone and water. DMSO <1 mg/mL. "Barza M, Scheife RT. Drug therapy reviews: Antimicrobial spectrum, pharmacology and therapeutic use of antibiotics--part 4: aminoglycosides. Am J Hosp Pharm. 1977 Jul;34(7):723-37. PMID: 407790.

 

Kawaguchi H. Discovery, chemistry, and activity of amikacin. J Infect Dis. 1976 Nov;134 SUPPL:S242-8. PMID: 825583.

 

King P, Citron DM, Griffith DC, et al. Effect of oxygen limitation on the in vitro activity of levofloxacin and other antibiotics administered by the aerosol route against Pseudomonas aeruginosa from cystic fibrosis patients. Diagn Microbiol Infect Dis. 2010 Feb;66(2):181-186. PMID: 19828274. " None Not dangerous goods.

LKT A5132 Amikacin Disulfate 1 g 95.1 Aminoglycoside; protein translation inhibitor. O-3-Amino-3-deoxy-α-D-glucopyranosyl-(1->6)-O- [6-amino-6-deoxy-α-D-glucopyranosyl-(1->4)]-N1- [(2S)-4-amino-2-hydroxy-1-oxobutyl]-2-deoxy-D- streptamine sulfate Amikacin sulfate; Amikin; Biklin; Lukadin; Mikavir; Novamin; Pierami 39831-55-5 ≥98% 781.76 C22H43N5O13 2H2SO4 C1C(C(C(C(C1NC(=O)C(CCN)O)OC2C(C(C(C(O2)CO)O)N)O)O)OC3C(C(C(C(O3)CN)O)O)O)N.OS(=O)(=O)O.OS(=O)(=O)O In DMSO at +4 for 2 weeks at -80 for 6 months. Ambient Ambient Soluble in water (50mg/mL). Insolulble in acetone and water. DMSO <1 mg/mL. "Barza M, Scheife RT. Drug therapy reviews: Antimicrobial spectrum, pharmacology and therapeutic use of antibiotics--part 4: aminoglycosides. Am J Hosp Pharm. 1977 Jul;34(7):723-37. PMID: 407790.

 

Kawaguchi H. Discovery, chemistry, and activity of amikacin. J Infect Dis. 1976 Nov;134 SUPPL:S242-8. PMID: 825583.

 

King P, Citron DM, Griffith DC, et al. Effect of oxygen limitation on the in vitro activity of levofloxacin and other antibiotics administered by the aerosol route against Pseudomonas aeruginosa from cystic fibrosis patients. Diagn Microbiol Infect Dis. 2010 Feb;66(2):181-186. PMID: 19828274. " None Not dangerous goods.

LKT A5132 Amikacin Disulfate 5 g 271.7 Aminoglycoside; protein translation inhibitor. O-3-Amino-3-deoxy-α-D-glucopyranosyl-(1->6)-O- [6-amino-6-deoxy-α-D-glucopyranosyl-(1->4)]-N1- [(2S)-4-amino-2-hydroxy-1-oxobutyl]-2-deoxy-D- streptamine sulfate Amikacin sulfate; Amikin; Biklin; Lukadin; Mikavir; Novamin; Pierami 39831-55-5 ≥98% 781.76 C22H43N5O13 2H2SO4 C1C(C(C(C(C1NC(=O)C(CCN)O)OC2C(C(C(C(O2)CO)O)N)O)O)OC3C(C(C(C(O3)CN)O)O)O)N.OS(=O)(=O)O.OS(=O)(=O)O In DMSO at +4 for 2 weeks at -80 for 6 months. Ambient Ambient Soluble in water (50mg/mL). Insolulble in acetone and water. DMSO <1 mg/mL. "Barza M, Scheife RT. Drug therapy reviews: Antimicrobial spectrum, pharmacology and therapeutic use of antibiotics--part 4: aminoglycosides. Am J Hosp Pharm. 1977 Jul;34(7):723-37. PMID: 407790.

 

Kawaguchi H. Discovery, chemistry, and activity of amikacin. J Infect Dis. 1976 Nov;134 SUPPL:S242-8. PMID: 825583.

 

King P, Citron DM, Griffith DC, et al. Effect of oxygen limitation on the in vitro activity of levofloxacin and other antibiotics administered by the aerosol route against Pseudomonas aeruginosa from cystic fibrosis patients. Diagn Microbiol Infect Dis. 2010 Feb;66(2):181-186. PMID: 19828274. " None Not dangerous goods.

LKT A5133 Amiloride Hydrochloride Dihydrate 500 mg 46.4 K+-sparing diuretic; ENaC and acid-sensing ion channel blocker, Na+/H+ antiporter inhibitor. 3,5-Diamino-N-(aminoiminomethyl)-6-chloropyrazine-carboxamide hydrochloride N-Amidino-3,5-diamino-6-chloropyrazinecarboxamide monohydrochloride; Amiprazidine 17440-83-4 ≥98% 302.12 C6H8ClN7O HCl 2H2O C1(=C(N=C(C(=N1)Cl)N)N)C(=O)N=C(N)N.O.O.Cl Ambient Ambient Soluble in water. "Ogram SA, Boone CD, McKenna R, et al. Amiloride inhibits the initiation of Coxsackievirus and poliovirus RNA replication by inhibiting VPg uridylylation. Virology. 2014 Sep;464-465:87-97. PMID: 25058507.

 

Yu X, Hu Y, Yu S. Effects of acid on vagal nociceptive afferent subtypes in guinea pig esophagus. Am J Physiol Gastrointest Liver Physiol. 2014 Aug 15;307(4):G471-8. PMID: 24994852.

 

Paar M, Pavenstädt H, Kusche-Vihrog K, et al. Endothelial sodium channels trigger endothelial salt sensitivity with aging. Hypertension. 2014 Aug;64(2):391-6. PMID: 24866143.

 

Bhagatwala J, Harris RA, Parikh SJ, et al. Epithelial sodium channel inhibition by amiloride on blood pressure and cardiovascular disease risk in young prehypertensives. J Clin Hypertens (Greenwich). 2014 Jan;16(1):47-53. PMID: 24410943.

" T "UN number: 2811     Class: 6.1     Packing Group: III

Proper shipping name: Toxic solid, organic, n.o.s. (Amiloride hydrochloride dihydrate)

Marine pollutant: No    Poison Inhalation Hazard: No"

LKT A5133 Amiloride Hydrochloride Dihydrate 1 g 62.5 K+-sparing diuretic; ENaC and acid-sensing ion channel blocker, Na+/H+ antiporter inhibitor. 3,5-Diamino-N-(aminoiminomethyl)-6-chloropyrazine-carboxamide hydrochloride N-Amidino-3,5-diamino-6-chloropyrazinecarboxamide monohydrochloride; Amiprazidine 17440-83-4 ≥98% 302.12 C6H8ClN7O HCl 2H2O C1(=C(N=C(C(=N1)Cl)N)N)C(=O)N=C(N)N.O.O.Cl Ambient Ambient Soluble in water. "Ogram SA, Boone CD, McKenna R, et al. Amiloride inhibits the initiation of Coxsackievirus and poliovirus RNA replication by inhibiting VPg uridylylation. Virology. 2014 Sep;464-465:87-97. PMID: 25058507.

 

Yu X, Hu Y, Yu S. Effects of acid on vagal nociceptive afferent subtypes in guinea pig esophagus. Am J Physiol Gastrointest Liver Physiol. 2014 Aug 15;307(4):G471-8. PMID: 24994852.

 

Paar M, Pavenstädt H, Kusche-Vihrog K, et al. Endothelial sodium channels trigger endothelial salt sensitivity with aging. Hypertension. 2014 Aug;64(2):391-6. PMID: 24866143.

 

Bhagatwala J, Harris RA, Parikh SJ, et al. Epithelial sodium channel inhibition by amiloride on blood pressure and cardiovascular disease risk in young prehypertensives. J Clin Hypertens (Greenwich). 2014 Jan;16(1):47-53. PMID: 24410943.

" T "UN number: 2811     Class: 6.1     Packing Group: III

Proper shipping name: Toxic solid, organic, n.o.s. (Amiloride hydrochloride dihydrate)

Marine pollutant: No    Poison Inhalation Hazard: No"

LKT A5133 Amiloride Hydrochloride Dihydrate 5 g 226.5 K+-sparing diuretic; ENaC and acid-sensing ion channel blocker, Na+/H+ antiporter inhibitor. 3,5-Diamino-N-(aminoiminomethyl)-6-chloropyrazine-carboxamide hydrochloride N-Amidino-3,5-diamino-6-chloropyrazinecarboxamide monohydrochloride; Amiprazidine 17440-83-4 ≥98% 302.12 C6H8ClN7O HCl 2H2O C1(=C(N=C(C(=N1)Cl)N)N)C(=O)N=C(N)N.O.O.Cl Ambient Ambient Soluble in water. "Ogram SA, Boone CD, McKenna R, et al. Amiloride inhibits the initiation of Coxsackievirus and poliovirus RNA replication by inhibiting VPg uridylylation. Virology. 2014 Sep;464-465:87-97. PMID: 25058507.

 

Yu X, Hu Y, Yu S. Effects of acid on vagal nociceptive afferent subtypes in guinea pig esophagus. Am J Physiol Gastrointest Liver Physiol. 2014 Aug 15;307(4):G471-8. PMID: 24994852.

 

Paar M, Pavenstädt H, Kusche-Vihrog K, et al. Endothelial sodium channels trigger endothelial salt sensitivity with aging. Hypertension. 2014 Aug;64(2):391-6. PMID: 24866143.

 

Bhagatwala J, Harris RA, Parikh SJ, et al. Epithelial sodium channel inhibition by amiloride on blood pressure and cardiovascular disease risk in young prehypertensives. J Clin Hypertens (Greenwich). 2014 Jan;16(1):47-53. PMID: 24410943.

" T "UN number: 2811     Class: 6.1     Packing Group: III

Proper shipping name: Toxic solid, organic, n.o.s. (Amiloride hydrochloride dihydrate)

Marine pollutant: No    Poison Inhalation Hazard: No"

LKT A5134 Aminophylline Anhydrous 25 g 54.4 Adenosine antagonist, PDE inhibitor. 3,7-Dihydro-1,3-dimethyl-1H-purine-2,6-dione compd with 1,2-ethanediamine (2:1) Aminophylline; Afonilum; Cardophylin; Pecram; Phyllotemp; Tefamin 317-34-0 ≥98% 420.43 C16H24N10O4 CN1C2=C(C(=O)N(C1=O)C)NC=N2CN1C2=C(C(=O)N(C1=O)C)NC=N2.C(CN)N Keep tightly closed. Ambient 4°C Soluble in water. Insoluble in alcohol and ether. "Nickels TJ, Schwartz AD, Blevins DE, et al. Effect of theophylline and aminophylline on transmitter release at the mammalian neuromuscular junction is not mediated by cAMP. Clin Exp Pharmacol Physiol. 2006 May-Jun;33(5-6):465-70. PMID: 16700879.

 

Danahay H, Broadley KJ, McCabe PJ, et al. The potential roles of cytokines, IL-5 and IL-8, and plasma cortisol in the anti-inflammatory actions of phosphodiesterase inhibitors in sensitized guinea-pig airways. Pulm Pharmacol Ther. 1997 Oct-Dec;10(5-6):277-85. PMID: 9778491.

" Xn "UN number: 2811     Class: 6.1     Packing Group: III

Proper shipping name: Toxic solid, organic, n.o.s. (Aminophylline)

Marine pollutant: No     Poison Inhalation Hazard: No "

LKT A5134 Aminophylline Anhydrous 100 g 88.3 Adenosine antagonist, PDE inhibitor. 3,7-Dihydro-1,3-dimethyl-1H-purine-2,6-dione compd with 1,2-ethanediamine (2:1) Aminophylline; Afonilum; Cardophylin; Pecram; Phyllotemp; Tefamin 317-34-0 ≥98% 420.43 C16H24N10O4 CN1C2=C(C(=O)N(C1=O)C)NC=N2CN1C2=C(C(=O)N(C1=O)C)NC=N2.C(CN)N Keep tightly closed. Ambient 4°C Soluble in water. Insoluble in alcohol and ether. "Nickels TJ, Schwartz AD, Blevins DE, et al. Effect of theophylline and aminophylline on transmitter release at the mammalian neuromuscular junction is not mediated by cAMP. Clin Exp Pharmacol Physiol. 2006 May-Jun;33(5-6):465-70. PMID: 16700879.

 

Danahay H, Broadley KJ, McCabe PJ, et al. The potential roles of cytokines, IL-5 and IL-8, and plasma cortisol in the anti-inflammatory actions of phosphodiesterase inhibitors in sensitized guinea-pig airways. Pulm Pharmacol Ther. 1997 Oct-Dec;10(5-6):277-85. PMID: 9778491.

" Xn "UN number: 2811     Class: 6.1     Packing Group: III

Proper shipping name: Toxic solid, organic, n.o.s. (Aminophylline)

Marine pollutant: No     Poison Inhalation Hazard: No "

LKT A5134 Aminophylline Anhydrous 500 g 271.7 Adenosine antagonist, PDE inhibitor. 3,7-Dihydro-1,3-dimethyl-1H-purine-2,6-dione compd with 1,2-ethanediamine (2:1) Aminophylline; Afonilum; Cardophylin; Pecram; Phyllotemp; Tefamin 317-34-0 ≥98% 420.43 C16H24N10O4 CN1C2=C(C(=O)N(C1=O)C)NC=N2CN1C2=C(C(=O)N(C1=O)C)NC=N2.C(CN)N Keep tightly closed. Ambient 4°C Soluble in water. Insoluble in alcohol and ether. "Nickels TJ, Schwartz AD, Blevins DE, et al. Effect of theophylline and aminophylline on transmitter release at the mammalian neuromuscular junction is not mediated by cAMP. Clin Exp Pharmacol Physiol. 2006 May-Jun;33(5-6):465-70. PMID: 16700879.

 

Danahay H, Broadley KJ, McCabe PJ, et al. The potential roles of cytokines, IL-5 and IL-8, and plasma cortisol in the anti-inflammatory actions of phosphodiesterase inhibitors in sensitized guinea-pig airways. Pulm Pharmacol Ther. 1997 Oct-Dec;10(5-6):277-85. PMID: 9778491.

" Xn "UN number: 2811     Class: 6.1     Packing Group: III

Proper shipping name: Toxic solid, organic, n.o.s. (Aminophylline)

Marine pollutant: No     Poison Inhalation Hazard: No "

LKT A5135 Aminophylline Dihydrate 25 g 33.9 Xanthine derivative; adenosine antagonist, PDE inhibitor. 3,7-Dihydro-1,3-dimetheyl-1H-purine-2,6-dione Theophylline compound with ethylenediamine ≥98% 456.47 C16H24N10O4 2H2O CN1C2=C(C(=O)N(C1=O)C)NC=N2CN1C2=C(C(=O)N(C1=O)C)NC=N2.C(CN)N.O.O Keep tightly closed. Ambient Ambient Soluble in water (1g/5mL). Insoluble in alcohol and ether. "Nickels TJ, Schwartz AD, Blevins DE, et al. Effect of theophylline and aminophylline on transmitter release at the mammalian neuromuscular junction is not mediated by cAMP. Clin Exp Pharmacol Physiol. 2006 May-Jun;33(5-6):465-70. PMID: 16700879.

 

Danahay H, Broadley KJ, McCabe PJ, et al. The potential roles of cytokines, IL-5 and IL-8, and plasma cortisol in the anti-inflammatory actions of phosphodiesterase inhibitors in sensitized guinea-pig airways. Pulm Pharmacol Ther. 1997 Oct-Dec;10(5-6):277-85. PMID: 9778491.

" "UN number: 2811     Class: 6.1     Packing Group: III

Proper shipping name: Toxic solid, organic, n.o.s. (Aminophylline)"

LKT A5135 Aminophylline Dihydrate 100 g 67.9 Xanthine derivative; adenosine antagonist, PDE inhibitor. 3,7-Dihydro-1,3-dimetheyl-1H-purine-2,6-dione Theophylline compound with ethylenediamine ≥98% 456.47 C16H24N10O4 2H2O CN1C2=C(C(=O)N(C1=O)C)NC=N2CN1C2=C(C(=O)N(C1=O)C)NC=N2.C(CN)N.O.O Keep tightly closed. Ambient Ambient Soluble in water (1g/5mL). Insoluble in alcohol and ether. "Nickels TJ, Schwartz AD, Blevins DE, et al. Effect of theophylline and aminophylline on transmitter release at the mammalian neuromuscular junction is not mediated by cAMP. Clin Exp Pharmacol Physiol. 2006 May-Jun;33(5-6):465-70. PMID: 16700879.

 

Danahay H, Broadley KJ, McCabe PJ, et al. The potential roles of cytokines, IL-5 and IL-8, and plasma cortisol in the anti-inflammatory actions of phosphodiesterase inhibitors in sensitized guinea-pig airways. Pulm Pharmacol Ther. 1997 Oct-Dec;10(5-6):277-85. PMID: 9778491.

" "UN number: 2811     Class: 6.1     Packing Group: III

Proper shipping name: Toxic solid, organic, n.o.s. (Aminophylline)"

LKT A5135 Aminophylline Dihydrate 500 g 163.2 Xanthine derivative; adenosine antagonist, PDE inhibitor. 3,7-Dihydro-1,3-dimetheyl-1H-purine-2,6-dione Theophylline compound with ethylenediamine ≥98% 456.47 C16H24N10O4 2H2O CN1C2=C(C(=O)N(C1=O)C)NC=N2CN1C2=C(C(=O)N(C1=O)C)NC=N2C(CN)N.O.O Keep tightly closed. Ambient Ambient Soluble in water (1g/5mL). Insoluble in alcohol and ether. "Nickels TJ, Schwartz AD, Blevins DE, et al. Effect of theophylline and aminophylline on transmitter release at the mammalian neuromuscular junction is not mediated by cAMP. Clin Exp Pharmacol Physiol. 2006 May-Jun;33(5-6):465-70. PMID: 16700879.

 

Danahay H, Broadley KJ, McCabe PJ, et al. The potential roles of cytokines, IL-5 and IL-8, and plasma cortisol in the anti-inflammatory actions of phosphodiesterase inhibitors in sensitized guinea-pig airways. Pulm Pharmacol Ther. 1997 Oct-Dec;10(5-6):277-85. PMID: 9778491.

" "UN number: 2811     Class: 6.1     Packing Group: III

Proper shipping name: Toxic solid, organic, n.o.s. (Aminophylline)"

LKT A5160 Ampicillin Trihydrate 5 g 46.1 β-lactam; transpeptidase inhibitor. (2S,5R,6R)-6-[[(2R)-Aminophenylacetyl]amino]-3,3- dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2- carboxylic acid trihydtrate Alpen; Amcill; Amplital; Binotal; Cymbi; Penbritin; Polycillin; Totacillin; Totapen; Vidopen 7177-48-2 ≥97% 403.47 C16H19N3O4S 3H2O CC1(C(N2C(S1)C(C2=O)NC(=O)C(C3=CC=CC=C3)N)C(=O)O)C.O.O.O Ambient 4°C Sparingly soluble in water. Practically insoluble in acetone,alcohol, in ether and fatty oils. It disolves in dilute solutions of acids and of alkali hydroxides "Martin SI, Kaye KM. Beta-lactam antibiotics: newer formulations and newer agents. Infect Dis Clin North Am. 2004 Sep;18(3):603-19, ix. PMID: 15308278.

 

Demain AL. Production of beta-lactam antibiotics and its regulation. Proc Natl Sci Counc Repub China B. 1991 Oct;15(4):251-65. PMID: 1815263.

" Xi Not dangerous goods.

LKT A5160 Ampicillin Trihydrate 25 g 119.5 β-lactam; transpeptidase inhibitor. (2S,5R,6R)-6-[[(2R)-Aminophenylacetyl]amino]-3,3- dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2- carboxylic acid trihydtrate Alpen; Amcill; Amplital; Binotal; Cymbi; Penbritin; Polycillin; Totacillin; Totapen; Vidopen 7177-48-2 ≥97% 403.47 C16H19N3O4S 3H2O CC1(C(N2C(S1)C(C2=O)NC(=O)C(C3=CC=CC=C3)N)C(=O)O)C.O.O.O Ambient 4°C Sparingly soluble in water. Practically insoluble in acetone,alcohol, in ether and fatty oils. It disolves in dilute solutions of acids and of alkali hydroxides "Martin SI, Kaye KM. Beta-lactam antibiotics: newer formulations and newer agents. Infect Dis Clin North Am. 2004 Sep;18(3):603-19, ix. PMID: 15308278.

 

Demain AL. Production of beta-lactam antibiotics and its regulation. Proc Natl Sci Counc Repub China B. 1991 Oct;15(4):251-65. PMID: 1815263.

" Xi Not dangerous goods.

LKT A5160 Ampicillin Trihydrate 100 g 325.8 β-lactam; transpeptidase inhibitor. (2S,5R,6R)-6-[[(2R)-Aminophenylacetyl]amino]-3,3- dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2- carboxylic acid trihydtrate Alpen; Amcill; Amplital; Binotal; Cymbi; Penbritin; Polycillin; Totacillin; Totapen; Vidopen 7177-48-2 ≥97% 403.47 C16H19N3O4S 3H2O CC1(C(N2C(S1)C(C2=O)NC(=O)C(C3=CC=CC=C3)N)C(=O)O)C.O.O.O Ambient 4°C Sparingly soluble in water. Practically insoluble in acetone,alcohol, in ether and fatty oils. It disolves in dilute solutions of acids and of alkali hydroxides "Martin SI, Kaye KM. Beta-lactam antibiotics: newer formulations and newer agents. Infect Dis Clin North Am. 2004 Sep;18(3):603-19, ix. PMID: 15308278.

 

Demain AL. Production of beta-lactam antibiotics and its regulation. Proc Natl Sci Counc Repub China B. 1991 Oct;15(4):251-65. PMID: 1815263.

" Xi Not dangerous goods.

LKT A5161 Ampiroxicam 1 g 57.8 Piroxicam prodrug, NSAID; COX-1/2 inhibitor. Carbonic acid ethyl 1-[[2-methyl-3-[(2-pyridinyl- amino)carbonyl]-2H-1,2-benzothiazin-4-yl]oxy]ethyl ester S,S-dioxide CP-65703; Flucam 99464-64-9 ≥98% 447.46 C20H21N3O7S CCOC(=O)OC(C)OC1=C(N(S(=O)(=O)C2=CC=CC=C21)C)C(=O)NC3=CC=CC=N3 Ambient Ambient Soluble in alcohol. Insoluble in acetone. "Sai S, Fujii K, Hiranuma K, et al. Preoperative ampiroxicam reduces postoperative pain after hand surgery. J Hand Surg Br. 2001 Aug;26(4):377-9. PMID: 11469844.

 

Carty TJ, Marfat A, Moore PF, et al. Ampiroxicam, an anti-inflammatory agent which is a prodrug of piroxicam. Agents Actions. 1993 Jul;39(3-4):157-65. PMID: 8304243.

" Not dangerous goods.

LKT A5161 Ampiroxicam 5 g 150.4 Piroxicam prodrug, NSAID; COX-1/2 inhibitor. Carbonic acid ethyl 1-[[2-methyl-3-[(2-pyridinyl- amino)carbonyl]-2H-1,2-benzothiazin-4-yl]oxy]ethyl ester S,S-dioxide CP-65703; Flucam 99464-64-9 ≥98% 447.46 C20H21N3O7S CCOC(=O)OC(C)OC1=C(N(S(=O)(=O)C2=CC=CC=C21)C)C(=O)NC3=CC=CC=N3 Ambient Ambient Soluble in alcohol. Insoluble in acetone. "Sai S, Fujii K, Hiranuma K, et al. Preoperative ampiroxicam reduces postoperative pain after hand surgery. J Hand Surg Br. 2001 Aug;26(4):377-9. PMID: 11469844.

 

Carty TJ, Marfat A, Moore PF, et al. Ampiroxicam, an anti-inflammatory agent which is a prodrug of piroxicam. Agents Actions. 1993 Jul;39(3-4):157-65. PMID: 8304243.

" Not dangerous goods.

LKT A5161 Ampiroxicam 25 g 612.5 Piroxicam prodrug, NSAID; COX-1/2 inhibitor. Carbonic acid ethyl 1-[[2-methyl-3-[(2-pyridinyl- amino)carbonyl]-2H-1,2-benzothiazin-4-yl]oxy]ethyl ester S,S-dioxide CP-65703; Flucam 99464-64-9 ≥98% 447.46 C20H21N3O7S CCOC(=O)OC(C)OC1=C(N(S(=O)(=O)C2=CC=CC=C21)C)C(=O)NC3=CC=CC=N3 Ambient Ambient Soluble in alcohol. Insoluble in acetone. "Sai S, Fujii K, Hiranuma K, et al. Preoperative ampiroxicam reduces postoperative pain after hand surgery. J Hand Surg Br. 2001 Aug;26(4):377-9. PMID: 11469844.

 

Carty TJ, Marfat A, Moore PF, et al. Ampiroxicam, an anti-inflammatory agent which is a prodrug of piroxicam. Agents Actions. 1993 Jul;39(3-4):157-65. PMID: 8304243.

" Not dangerous goods.

LKT A5162 Amprolium Hydrochloride 25 g 51.1 Thiamine, coccidiostat; thiamine transporter inhibitor. 1-[(4-Amino-2-propyl-5-pyrimidinyl)methyl]-2-methylpyridinium chloride hydrochloride Amprol 137-88-2 ≥97% 315.24 C14H19ClN4 HCl CCCC1=NC=C(C(=N1)N)C[N+]2=CC=CC=C2C.Cl.[Cl-] Ambient Ambient Soluble in water, methanol, ethanol, and dimethyl- formamide. Practically insoluble in isopropanol, butanol, ethyl acetate and acetonitrile.. "Young G, Alley ML, Foster DM, et al. Efficacy of amprolium for the treatment of pathogenic Eimeria species in Boer goat kids. Vet Parasitol. 2011 Jun 10;178(3-4):346-9. PMID: 21333448.

 

Dudeja PK, Tyagi S, Gill R, et al. Evidence for a carrier-mediated mechanism for thiamine transport to human jejunal basolateral membrane vesicles. Dig Dis Sci. 2003 Jan;48(1):109-15. PMID: 12645798.

" Xn, Xi Not dangerous goods.

LKT A5162 Amprolium Hydrochloride 100 g 173 Thiamine, coccidiostat; thiamine transporter inhibitor. 1-[(4-Amino-2-propyl-5-pyrimidinyl)methyl]-2-methylpyridinium chloride hydrochloride Amprol 137-88-2 ≥97% 315.24 C14H19ClN4 HCl CCCC1=NC=C(C(=N1)N)C[N+]2=CC=CC=C2C.Cl.[Cl-] Ambient Ambient Soluble in water, methanol, ethanol, and dimethyl- formamide. Practically insoluble in isopropanol, butanol, ethyl acetate and acetonitrile.. "Young G, Alley ML, Foster DM, et al. Efficacy of amprolium for the treatment of pathogenic Eimeria species in Boer goat kids. Vet Parasitol. 2011 Jun 10;178(3-4):346-9. PMID: 21333448.

 

Dudeja PK, Tyagi S, Gill R, et al. Evidence for a carrier-mediated mechanism for thiamine transport to human jejunal basolateral membrane vesicles. Dig Dis Sci. 2003 Jan;48(1):109-15. PMID: 12645798.

" Xn, Xi Not dangerous goods.

LKT A5170 Amrinone 250 mg 61.1 Pyridine; PDE3 inhibitor. 5-Amino-(3,4'-bipyridin)-6(1H)-one Cartonic; Inocor; Vesistol; Wincoram 60719-84-8 ≥98% 187.2 C10H9N3O C1=CN=CC=C1C2=CNC(=O)C(=C2)N Ambient 4°C Insoluble in water. Slightly soluble in hot acetic acid and  dimethylformamide. Soluble in dilute inorganic acids. "Coons JC, McGraw M, Murali S. Pharmacotherapy for acute heart failure syndromes. Am J Health Syst Pharm. 2011 Jan 1;68(1):21-35. PMID: 21164062.

 

van der Zypp A, Rechtman M, Majewski H. The role of cyclic nucleotides and calcium in the relaxation produced by amrinone in rat aorta. Gen Pharmacol. 2000 Apr;34(4):245-53. PMID: 11282218.

 

Hamada Y, Kawachi K, Yamamoto T, et al. Effects of single administration of a phosphodiesterase III inhibitor during cardiopulmonary bypass: comparison of milrinone and amrinone. Jpn Circ J. 1999 Aug;63(8):605-9. PMID: 10478810.

" Xn, Xi, T "UN number: 2811      Class:  6.1     Packing group:  III

Proper shipping name:  Toxic solids, organic, n.o.s. (Amrinone)

Marine pollutant:  No     Poison inhalation hazard:  No."

LKT A5170 Amrinone 1 g 176.6 Pyridine; PDE3 inhibitor. 5-Amino-(3,4'-bipyridin)-6(1H)-one Cartonic; Inocor; Vesistol; Wincoram 60719-84-8 ≥98% 187.2 C10H9N3O C1=CN=CC=C1C2=CNC(=O)C(=C2)N Ambient 4°C Insoluble in water. Slightly soluble in hot acetic acid and  dimethylformamide. Soluble in dilute inorganic acids. "Coons JC, McGraw M, Murali S. Pharmacotherapy for acute heart failure syndromes. Am J Health Syst Pharm. 2011 Jan 1;68(1):21-35. PMID: 21164062.

 

van der Zypp A, Rechtman M, Majewski H. The role of cyclic nucleotides and calcium in the relaxation produced by amrinone in rat aorta. Gen Pharmacol. 2000 Apr;34(4):245-53. PMID: 11282218.

 

Hamada Y, Kawachi K, Yamamoto T, et al. Effects of single administration of a phosphodiesterase III inhibitor during cardiopulmonary bypass: comparison of milrinone and amrinone. Jpn Circ J. 1999 Aug;63(8):605-9. PMID: 10478810.

" Xn, Xi, T "UN number: 2811      Class:  6.1     Packing group:  III

Proper shipping name:  Toxic solids, organic, n.o.s. (Amrinone)

Marine pollutant:  No     Poison inhalation hazard:  No."

LKT A5193 Amygdalin 1 g 42 Glucoside found in stone fruits and apples. [(6-O-β-D-glucopyranosyl-beta-D-gluco-pyranosyl- β-D-gluco-pyranosyl)oxy]-benzeneacetonitrile Amygdaloside 29883-15-6 ≥98% 457.43 C20H27NO11 C1=CC=C(C=C1)C(C#N)OC2C(C(C(C(O2)COC3C(C(C(C(O3)CO)O)O)O)O)O)O Ambient Ambient Soluble in hot water (0.1g/mL) or alcohol (1g/900mL). "Chen Y, Ma J, Wang F, et al. Amygdalin induces apoptosis in human cervical cancer cell line HeLa cells. Immunopharmacol Immunotoxicol. 2013 Feb;35(1):43-51. PMID: 23137229.

 

Hwang HJ, Kim P, Kim CJ, et al. Antinociceptive effect of amygdalin isolated from Prunus armeniaca on formalin-induced pain in rats. Biol Pharm Bull. 2008 Aug;31(8):1559-64. PMID: 18670089.

 

Chang HK, Shin MS, Yang HY, et al. Amygdalin induces apoptosis through regulation of Bax and Bcl-2 expressions in human DU145 and LNCaP prostate cancer cells. Biol Pharm Bull. 2006 Aug;29(8):1597-602. PMID: 16880611.

" Xn Not dangerous goods.

LKT A5193 Amygdalin 5 g 63 Glucoside found in stone fruits and apples. [(6-O-β-D-glucopyranosyl-beta-D-gluco-pyranosyl- β-D-gluco-pyranosyl)oxy]-benzeneacetonitrile Amygdaloside 29883-15-6 ≥98% 457.43 C20H27NO11 C1=CC=C(C=C1)C(C#N)OC2C(C(C(C(O2)COC3C(C(C(C(O3)CO)O)O)O)O)O)O Ambient Ambient Soluble in hot water (0.1g/mL) or alcohol (1g/900mL). "Chen Y, Ma J, Wang F, et al. Amygdalin induces apoptosis in human cervical cancer cell line HeLa cells. Immunopharmacol Immunotoxicol. 2013 Feb;35(1):43-51. PMID: 23137229.

 

Hwang HJ, Kim P, Kim CJ, et al. Antinociceptive effect of amygdalin isolated from Prunus armeniaca on formalin-induced pain in rats. Biol Pharm Bull. 2008 Aug;31(8):1559-64. PMID: 18670089.

 

Chang HK, Shin MS, Yang HY, et al. Amygdalin induces apoptosis through regulation of Bax and Bcl-2 expressions in human DU145 and LNCaP prostate cancer cells. Biol Pharm Bull. 2006 Aug;29(8):1597-602. PMID: 16880611.

" Xn Not dangerous goods.

LKT A5193 Amygdalin 25 g 252.1 Glucoside found in stone fruits and apples. [(6-O-β-D-glucopyranosyl-beta-D-gluco-pyranosyl- β-D-gluco-pyranosyl)oxy]-benzeneacetonitrile Amygdaloside 29883-15-6 ≥98% 457.43 C20H27NO11 C1=CC=C(C=C1)C(C#N)OC2C(C(C(C(O2)COC3C(C(C(C(O3)CO)O)O)O)O)O)O Ambient Ambient Soluble in hot water (0.1g/mL) or alcohol (1g/900mL). "Chen Y, Ma J, Wang F, et al. Amygdalin induces apoptosis in human cervical cancer cell line HeLa cells. Immunopharmacol Immunotoxicol. 2013 Feb;35(1):43-51. PMID: 23137229.

 

Hwang HJ, Kim P, Kim CJ, et al. Antinociceptive effect of amygdalin isolated from Prunus armeniaca on formalin-induced pain in rats. Biol Pharm Bull. 2008 Aug;31(8):1559-64. PMID: 18670089.

 

Chang HK, Shin MS, Yang HY, et al. Amygdalin induces apoptosis through regulation of Bax and Bcl-2 expressions in human DU145 and LNCaP prostate cancer cells. Biol Pharm Bull. 2006 Aug;29(8):1597-602. PMID: 16880611.

" Xn Not dangerous goods.

LKT A5202 Anabasine Hydrochloride 25 mg 46.4 Alkaloid originally found in species of Nicotiana, depolarizing NMJ blocker; nAChR antagonist, aromatase inhibitor, teratogen. 3-(2-Piperidinyl)pyridine hydrochloride 15251-47-5 ≥98% 198.73 C10H14N2 HCl C1CCNC(C1)C2=CN=CC=C2.Cl Protect from light. Ambient 4°C Soluble in water or alcohol. "Green BT, Lee ST, Welch KD, et al. Plant alkaloids that cause developmental defects through the disruption of cholinergic neurotransmission. Birth Defects Res C Embryo Today. 2013 Dec;99(4):235-46. PMID: 24339035.

 

Shimomura M, Yokota M, Ihara M, et al. Role in the selectivity of neonicotinoids of insect-specific basic residues in loop D of the nicotinic acetylcholine receptor agonist binding site. Mol Pharmacol. 2006 Oct;70(4):1255-63. PMID: 16868180.

 

Jacob P 3rd, Yu L, Shulgin AT, Benowitz NL. Minor tobacco alkaloids as biomarkers for tobacco use: comparison of users of cigarettes, smokeless tobacco, cigars, and pipes. Am J Public Health. 1999 May;89(5):731-6. PMID: 10224986.

 

Barbieri RL, Gochberg J, Ryan KJ. Nicotine, cotinine, and anabasine inhibit aromatase in human trophoblast in vitro. J Clin Invest. 1986 Jun;77(6):1727-33. PMID: 3711333.

" "UN number: 1544     Class: 6.1     Packing Group: III

Proper shipping name: Alkaloid salts, solid, n.o.s. (Anabasine hydrochloride)"

LKT A5202 Anabasine Hydrochloride 100 mg 120.1 Alkaloid originally found in species of Nicotiana, depolarizing NMJ blocker; nAChR antagonist, aromatase inhibitor, teratogen. 3-(2-Piperidinyl)pyridine hydrochloride 15251-47-5 ≥98% 198.73 C10H14N2 HCl C1CCNC(C1)C2=CN=CC=C2.Cl Protect from light. Ambient 4°C Soluble in water or alcohol. "Green BT, Lee ST, Welch KD, et al. Plant alkaloids that cause developmental defects through the disruption of cholinergic neurotransmission. Birth Defects Res C Embryo Today. 2013 Dec;99(4):235-46. PMID: 24339035.

 

Shimomura M, Yokota M, Ihara M, et al. Role in the selectivity of neonicotinoids of insect-specific basic residues in loop D of the nicotinic acetylcholine receptor agonist binding site. Mol Pharmacol. 2006 Oct;70(4):1255-63. PMID: 16868180.

 

Jacob P 3rd, Yu L, Shulgin AT, Benowitz NL. Minor tobacco alkaloids as biomarkers for tobacco use: comparison of users of cigarettes, smokeless tobacco, cigars, and pipes. Am J Public Health. 1999 May;89(5):731-6. PMID: 10224986.

 

Barbieri RL, Gochberg J, Ryan KJ. Nicotine, cotinine, and anabasine inhibit aromatase in human trophoblast in vitro. J Clin Invest. 1986 Jun;77(6):1727-33. PMID: 3711333.

" "UN number: 1544     Class: 6.1     Packing Group: III

Proper shipping name: Alkaloid salts, solid, n.o.s. (Anabasine hydrochloride)"

LKT A5219 Anethole Trithione 25 mg 104.3 Oltipraz analog, salivary gland secretion enhancer. 5-(4-Methoxyphenyl)-3H-1,2-dithiole-3-thione Trithioanethole; ADT; Felviten; Mucinol; Sialor; Sulfarlem 532-11-6 ≥98% 240.37 C10H8OS3 COC1=CC=C(C=C1)C2=CC(=S)SS2 Ambient 4°C Soluble in pyridine, chloroform, benzene, dioxane, and carbon disulfide. Slightly soluble in ether, acetone, ethyl acetate and cyclohexane. Practically insoluble in water. "Nagano T, Takeyama M. Enhancement of salivary secretion and neuropeptide (substance P, alpha-calcitonin gene-related peptide) levels in saliva by chronic anethole trithione treatment. J Pharm Pharmacol. 2001 Dec;53(12):1697-702. PMID: 11804400.

 

Hamada T, Nakane T, Kimura T, et al. Treatment of xerostomia with the bile secretion-stimulating drug anethole trithione: a clinical trial. Am J Med Sci. 1999 Sep;318(3):146-51. PMID: 10487404.

" Not dangerous goods.

LKT A5219 Anethole Trithione 100 mg 333.7 Oltipraz analog, salivary gland secretion enhancer. 5-(4-Methoxyphenyl)-3H-1,2-dithiole-3-thione Trithioanethole; ADT; Felviten; Mucinol; Sialor; Sulfarlem 532-11-6 ≥98% 240.37 C10H8OS3 COC1=CC=C(C=C1)C2=CC(=S)SS2 Ambient 4°C Soluble in pyridine, chloroform, benzene, dioxane, and carbon disulfide. Slightly soluble in ether, acetone, ethyl acetate and cyclohexane. Practically insoluble in water. "Nagano T, Takeyama M. Enhancement of salivary secretion and neuropeptide (substance P, alpha-calcitonin gene-related peptide) levels in saliva by chronic anethole trithione treatment. J Pharm Pharmacol. 2001 Dec;53(12):1697-702. PMID: 11804400.

 

Hamada T, Nakane T, Kimura T, et al. Treatment of xerostomia with the bile secretion-stimulating drug anethole trithione: a clinical trial. Am J Med Sci. 1999 Sep;318(3):146-51. PMID: 10487404.

" Not dangerous goods.

LKT A5219 Anethole Trithione 500 mg 1049.6 Oltipraz analog, salivary gland secretion enhancer. 5-(4-Methoxyphenyl)-3H-1,2-dithiole-3-thione Trithioanethole; ADT; Felviten; Mucinol; Sialor; Sulfarlem 532-11-6 ≥98% 240.37 C10H8OS3 COC1=CC=C(C=C1)C2=CC(=S)SS2 Ambient 4°C Soluble in pyridine, chloroform, benzene, dioxane, and carbon disulfide. Slightly soluble in ether, acetone, ethyl acetate and cyclohexane. Practically insoluble in water. "Nagano T, Takeyama M. Enhancement of salivary secretion and neuropeptide (substance P, alpha-calcitonin gene-related peptide) levels in saliva by chronic anethole trithione treatment. J Pharm Pharmacol. 2001 Dec;53(12):1697-702. PMID: 11804400.

 

Hamada T, Nakane T, Kimura T, et al. Treatment of xerostomia with the bile secretion-stimulating drug anethole trithione: a clinical trial. Am J Med Sci. 1999 Sep;318(3):146-51. PMID: 10487404.

" Not dangerous goods.

LKT A5225 α-ANP (1-28), human 0.5 mg 324 Endogenous cardiomodulatory peptide; NPR-A agonist. Atrial Natriuretic Peptide human; Urodilatin; hANF 91917-63-4 ≥95% 3080.46 C127H203N45O39S3 CCC(C)C(C(=O)NCC(=O)NC(C)C(=O)NC(CCC(=O)N)C(=O)NC(CO)C(=O)NCC(=O)NC(CC(C)C)C(=O)NCC(=O)NC(CS)C(=O)NC(CC(=O)N)C(=O)NC(CO)C(=O)NC(CC1=CC=CC=C1)C(=O)NC(CCCNC(=N)N)C(=O)NC(CC2=CC=C(C=C2)O)C(=O)O)NC(=O)C(CCCNC(=N)N)NC(=O)C(CC(=O)O)NC(=O)C(CCSC)NC(=O)C(CCCNC(=N)N)NC(=O)CNC(=O)CNC(=O)C(CC3=CC=CC=C3)NC(=O)C(CS)NC(=O)C(CO)NC(=O)C(CO)NC(=O)C(CCCNC(=N)N)NC(=O)C(CCCNC(=N)N)NC(=O)C(CC(C)C)NC(=O)C(CO)N Store in a cool, dry place. Ambient -20°C Soluble in 5% aceteic acid. "Vesely DL. New anticancer agents: hormones made within the heart. Anticancer Res. 2012 Jul;32(7):2515-21. PMID: 22753708.

 

Woodard GE, Rosado JA. Natriuretic peptides in vascular physiology and pathology. Int Rev Cell Mol Biol. 2008;268:59-93. PMID: 18703404."

LKT A5225 α-ANP (1-28), human 1 mg 552 Endogenous cardiomodulatory peptide; NPR-A agonist. Atrial Natriuretic Peptide human; Urodilatin; hANF 91917-63-4 ≥95% 3080.46 C127H203N45O39S3 CCC(C)C(C(=O)NCC(=O)NC(C)C(=O)NC(CCC(=O)N)C(=O)NC(CO)C(=O)NCC(=O)NC(CC(C)C)C(=O)NCC(=O)NC(CS)C(=O)NC(CC(=O)N)C(=O)NC(CO)C(=O)NC(CC1=CC=CC=C1)C(=O)NC(CCCNC(=N)N)C(=O)NC(CC2=CC=C(C=C2)O)C(=O)O)NC(=O)C(CCCNC(=N)N)NC(=O)C(CC(=O)O)NC(=O)C(CCSC)NC(=O)C(CCCNC(=N)N)NC(=O)CNC(=O)CNC(=O)C(CC3=CC=CC=C3)NC(=O)C(CS)NC(=O)C(CO)NC(=O)C(CO)NC(=O)C(CCCNC(=N)N)NC(=O)C(CCCNC(=N)N)NC(=O)C(CC(C)C)NC(=O)C(CO)N Store in a cool, dry place. Ambient -20°C Soluble in 5% aceteic acid. "Vesely DL. New anticancer agents: hormones made within the heart. Anticancer Res. 2012 Jul;32(7):2515-21. PMID: 22753708.

 

Woodard GE, Rosado JA. Natriuretic peptides in vascular physiology and pathology. Int Rev Cell Mol Biol. 2008;268:59-93. PMID: 18703404."

LKT A5225 α-ANP (1-28), human 2.5 mg 972.1 Endogenous cardiomodulatory peptide; NPR-A agonist. Atrial Natriuretic Peptide human; Urodilatin; hANF 91917-63-4 ≥95% 3080.46 C127H203N45O39S3 CCC(C)C(C(=O)NCC(=O)NC(C)C(=O)NC(CCC(=O)N)C(=O)NC(CO)C(=O)NCC(=O)NC(CC(C)C)C(=O)NCC(=O)NC(CS)C(=O)NC(CC(=O)N)C(=O)NC(CO)C(=O)NC(CC1=CC=CC=C1)C(=O)NC(CCCNC(=N)N)C(=O)NC(CC2=CC=C(C=C2)O)C(=O)O)NC(=O)C(CCCNC(=N)N)NC(=O)C(CC(=O)O)NC(=O)C(CCSC)NC(=O)C(CCCNC(=N)N)NC(=O)CNC(=O)CNC(=O)C(CC3=CC=CC=C3)NC(=O)C(CS)NC(=O)C(CO)NC(=O)C(CO)NC(=O)C(CCCNC(=N)N)NC(=O)C(CCCNC(=N)N)NC(=O)C(CC(C)C)NC(=O)C(CO)N Store in a cool, dry place. Ambient -20°C Soluble in 5% aceteic acid. "Vesely DL. New anticancer agents: hormones made within the heart. Anticancer Res. 2012 Jul;32(7):2515-21. PMID: 22753708.

 

Woodard GE, Rosado JA. Natriuretic peptides in vascular physiology and pathology. Int Rev Cell Mol Biol. 2008;268:59-93. PMID: 18703404."

LKT A5228 Angiogenin 50 µg 1878.2 Small protein, cleaves RNA. Angiogenic factor (human adenocarcinoma HT-29) 97950-81-7 ≥98% 14.4 Ambient -20°C "Gao X, Xu Z. Mechanisms of action of angiogenin. Acta Biochim Biophys Sin (Shanghai). 2008 Jul;40(7):619-24. PMID: 18604453.

 

Tello-Montoliu A, Patel JV, Lip GY. Angiogenin: a review of the pathophysiology and potential clinical applications. J Thromb Haemost. 2006 Sep;4(9):1864-74. PMID: 16961595.

 

Leland PA, Staniszewski KE, Park C, et al. The ribonucleolytic activity of angiogenin. Biochemistry. 2002 Jan 29;41(4):1343-50. PMID: 11802736.

"

LKT A5234 Amisulpride 25 mg 61.1 5-HT7 and D2/3 antagonist. 71675-85-9 ≥98% 369.48 C17H27N3O4S CCN1CCCC1CNC(=O)C2=CC(=C(C=C2OC)N)S(=O)(=O)CC Ambient Ambient "Meltzer HY. Serotonergic mechanisms as targets for existing and novel antipsychotics. Handb Exp Pharmacol. 2012;(212):87-124. PMID: 23129329.

 

Park SW, Seo MK, Cho HY, et al. Differential effects of amisulpride and haloperidol on dopamine D2 receptor-mediated signaling in SH-SY5Y cells. Neuropharmacology. 2011 Sep;61(4):761-9. PMID: 21663752.

 

Möller HJ. Amisulpride: limbic specificity and the mechanism of antipsychotic atypicality. Prog Neuropsychopharmacol Biol Psychiatry. 2003 Oct;27(7):1101-11. PMID: 14642970.

" Xn Not dangerous goods.

LKT A5234 Amisulpride 100 mg 163.2 5-HT7 and D2/3 antagonist. 71675-85-9 ≥98% 369.48 C17H27N3O4S CCN1CCCC1CNC(=O)C2=CC(=C(C=C2OC)N)S(=O)(=O)CC Ambient Ambient "Meltzer HY. Serotonergic mechanisms as targets for existing and novel antipsychotics. Handb Exp Pharmacol. 2012;(212):87-124. PMID: 23129329.

 

Park SW, Seo MK, Cho HY, et al. Differential effects of amisulpride and haloperidol on dopamine D2 receptor-mediated signaling in SH-SY5Y cells. Neuropharmacology. 2011 Sep;61(4):761-9. PMID: 21663752.

 

Möller HJ. Amisulpride: limbic specificity and the mechanism of antipsychotic atypicality. Prog Neuropsychopharmacol Biol Psychiatry. 2003 Oct;27(7):1101-11. PMID: 14642970.

" Xn Not dangerous goods.

LKT A5234 Amisulpride 500 mg 502.8 5-HT7 and D2/3 antagonist. 71675-85-9 ≥98% 369.48 C17H27N3O4S CCN1CCCC1CNC(=O)C2=CC(=C(C=C2OC)N)S(=O)(=O)CC Ambient Ambient "Meltzer HY. Serotonergic mechanisms as targets for existing and novel antipsychotics. Handb Exp Pharmacol. 2012;(212):87-124. PMID: 23129329.

 

Park SW, Seo MK, Cho HY, et al. Differential effects of amisulpride and haloperidol on dopamine D2 receptor-mediated signaling in SH-SY5Y cells. Neuropharmacology. 2011 Sep;61(4):761-9. PMID: 21663752.

 

Möller HJ. Amisulpride: limbic specificity and the mechanism of antipsychotic atypicality. Prog Neuropsychopharmacol Biol Psychiatry. 2003 Oct;27(7):1101-11. PMID: 14642970.

" Xn Not dangerous goods.

LKT A5235 Amitriptyline Hydrochloride 10 g 42.1 FIASMA, σ1, RyR2, TrkA/B agonist, 5-HT2/6/7, M1-5 mAChR, histamine H1/4, α1-adr. antagonist, SERT, NET inhibitor, Kv1.1/7.2/7.3 K+, L-type Ca2+ channel blocker. 3-(10,11-Dihydro-5H-dibenzo[a,d]cycloheptene-5-ylidene)-N,N-dimethyl-1-propanamine hydrochloride 549-18-8 ≥98% 313.86 C20H23N HCl CN(C)CCC=C1C2=CC=CC=C2CCC3=CC=CC=C31.Cl Ambient Ambient Soluble in water, ethanol, DMSO "Effects of chronic administration of amitriptyline, gabapentin and minocycline on spinal brain-derived neurotrophic factor expression and neuropathic pain behavior in a rat chronic constriction injury model.

Vanelderen P, Rouwette T, Kozicz T, Heylen R, Van Zundert J, Roubos EW, Vissers K.

Reg Anesth Pain Med. 2013 Mar-Apr;38(2):124-30. PMID: 23337936.

 

Ramakrishna D, Subhash MN. Differential modulation of α-1 adrenoceptor subtypes by antidepressants in the rat brain. J Neural Transm. 2010 Dec;117(12):1423-30. PMID: 21136124.

 

Yan L, Wang Q, Fu Q, et al. Amitriptyline inhibits currents and decreases the mRNA expression of voltage-gated sodium channels in cultured rat cortical neurons. Brain Res. 2010 Jun 8;1336:1-9. PMID: 20398637.

 

Jang SW, Liu X, Chan CB, et al. Amitriptyline is a TrkA and TrkB receptor agonist that promotes TrkA/TrkB heterodimerization and has potent neurotrophic activity. Chem Biol. 2009 Jun 26;16(6):644-56. PMID: 19549602.

 

Chopra N, Laver D, Davies SS, et al. Amitriptyline activates cardiac ryanodine channels and causes spontaneous sarcoplasmic reticulum calcium release. Mol Pharmacol. 2009 Jan;75(1):183-95. PMID: 18845675.

 

Werling LL, Keller A, Frank JG, et al. A comparison of the binding profiles of dextromethorphan, memantine, fluoxetine and amitriptyline: treatment of involuntary emotional expression disorder. Exp Neurol. 2007 Oct;207(2):248-57. PMID: 17689532.

 

Punke MA, Friederich P. Amitriptyline is a potent blocker of human Kv1.1 and Kv7.2/7.3 channels. Anesth Analg. 2007 May;104(5):1256-64. PMID: 17456683.

 

Owens MJ, Morgan WN, Plott SJ, et al. Neurotransmitter receptor and transporter binding profile of antidepressants and their metabolites. J Pharmacol Exp Ther. 1997 Dec;283(3):1305-22. PMID: 9400006.

 

Hamon M, Gozlan H, Bourgoin S, et al. Opioid receptors and neuropeptides in the CNS in rats treated chronically with amoxapine or amitriptyline. Neuropharmacology. 1987 Jun;26(6):531-9. PMID: 3037421.

" Xn, T+, Xi, Carc., "UN number: 2811     Class: 6.1     Packing Group: III

Proper shipping name: Toxic solids, organic, n.o.s. (Amitriptyline hydrochloride)

Marine pollutant: No     Poison Inhalation Hazard: No"

LKT A5235 Amitriptyline Hydrochloride 25 g 84.3 FIASMA, σ1, RyR2, TrkA/B agonist, 5-HT2/6/7, M1-5 mAChR, histamine H1/4, α1-adr. antagonist, SERT, NET inhibitor, Kv1.1/7.2/7.3 K+, L-type Ca2+ channel blocker. 3-(10,11-Dihydro-5H-dibenzo[a,d]cycloheptene-5-ylidene)-N,N-dimethyl-1-propanamine hydrochloride 549-18-8 ≥98% 313.86 C20H23N HCl CN(C)CCC=C1C2=CC=CC=C2CCC3=CC=CC=C31.Cl Ambient Ambient Soluble in water, ethanol, DMSO "Effects of chronic administration of amitriptyline, gabapentin and minocycline on spinal brain-derived neurotrophic factor expression and neuropathic pain behavior in a rat chronic constriction injury model.

Vanelderen P, Rouwette T, Kozicz T, Heylen R, Van Zundert J, Roubos EW, Vissers K.

Reg Anesth Pain Med. 2013 Mar-Apr;38(2):124-30. PMID: 23337936.

 

Ramakrishna D, Subhash MN. Differential modulation of α-1 adrenoceptor subtypes by antidepressants in the rat brain. J Neural Transm. 2010 Dec;117(12):1423-30. PMID: 21136124.

 

Yan L, Wang Q, Fu Q, et al. Amitriptyline inhibits currents and decreases the mRNA expression of voltage-gated sodium channels in cultured rat cortical neurons. Brain Res. 2010 Jun 8;1336:1-9. PMID: 20398637.

 

Jang SW, Liu X, Chan CB, et al. Amitriptyline is a TrkA and TrkB receptor agonist that promotes TrkA/TrkB heterodimerization and has potent neurotrophic activity. Chem Biol. 2009 Jun 26;16(6):644-56. PMID: 19549602.

 

Chopra N, Laver D, Davies SS, et al. Amitriptyline activates cardiac ryanodine channels and causes spontaneous sarcoplasmic reticulum calcium release. Mol Pharmacol. 2009 Jan;75(1):183-95. PMID: 18845675.

 

Werling LL, Keller A, Frank JG, et al. A comparison of the binding profiles of dextromethorphan, memantine, fluoxetine and amitriptyline: treatment of involuntary emotional expression disorder. Exp Neurol. 2007 Oct;207(2):248-57. PMID: 17689532.

 

Punke MA, Friederich P. Amitriptyline is a potent blocker of human Kv1.1 and Kv7.2/7.3 channels. Anesth Analg. 2007 May;104(5):1256-64. PMID: 17456683.

 

Owens MJ, Morgan WN, Plott SJ, et al. Neurotransmitter receptor and transporter binding profile of antidepressants and their metabolites. J Pharmacol Exp Ther. 1997 Dec;283(3):1305-22. PMID: 9400006.

 

Hamon M, Gozlan H, Bourgoin S, et al. Opioid receptors and neuropeptides in the CNS in rats treated chronically with amoxapine or amitriptyline. Neuropharmacology. 1987 Jun;26(6):531-9. PMID: 3037421.

" Xn, T+, Xi, Carc., "UN number: 2811     Class: 6.1     Packing Group: III

Proper shipping name: Toxic solids, organic, n.o.s. (Amitriptyline hydrochloride)

Marine pollutant: No     Poison Inhalation Hazard: No"

LKT A5235 Amitriptyline Hydrochloride 100 g 243.8 FIASMA, σ1, RyR2, TrkA/B agonist, 5-HT2/6/7, M1-5 mAChR, histamine H1/4, α1-adr. antagonist, SERT, NET inhibitor, Kv1.1/7.2/7.3 K+, L-type Ca2+ channel blocker. 3-(10,11-Dihydro-5H-dibenzo[a,d]cycloheptene-5-ylidene)-N,N-dimethyl-1-propanamine hydrochloride 549-18-8 ≥98% 313.86 C20H23N HCl CN(C)CCC=C1C2=CC=CC=C2CCC3=CC=CC=C31.Cl Ambient Ambient Soluble in water, ethanol, DMSO "Effects of chronic administration of amitriptyline, gabapentin and minocycline on spinal brain-derived neurotrophic factor expression and neuropathic pain behavior in a rat chronic constriction injury model.

Vanelderen P, Rouwette T, Kozicz T, Heylen R, Van Zundert J, Roubos EW, Vissers K.

Reg Anesth Pain Med. 2013 Mar-Apr;38(2):124-30. PMID: 23337936.

 

Ramakrishna D, Subhash MN. Differential modulation of α-1 adrenoceptor subtypes by antidepressants in the rat brain. J Neural Transm. 2010 Dec;117(12):1423-30. PMID: 21136124.

 

Yan L, Wang Q, Fu Q, et al. Amitriptyline inhibits currents and decreases the mRNA expression of voltage-gated sodium channels in cultured rat cortical neurons. Brain Res. 2010 Jun 8;1336:1-9. PMID: 20398637.

 

Jang SW, Liu X, Chan CB, et al. Amitriptyline is a TrkA and TrkB receptor agonist that promotes TrkA/TrkB heterodimerization and has potent neurotrophic activity. Chem Biol. 2009 Jun 26;16(6):644-56. PMID: 19549602.

 

Chopra N, Laver D, Davies SS, et al. Amitriptyline activates cardiac ryanodine channels and causes spontaneous sarcoplasmic reticulum calcium release. Mol Pharmacol. 2009 Jan;75(1):183-95. PMID: 18845675.

 

Werling LL, Keller A, Frank JG, et al. A comparison of the binding profiles of dextromethorphan, memantine, fluoxetine and amitriptyline: treatment of involuntary emotional expression disorder. Exp Neurol. 2007 Oct;207(2):248-57. PMID: 17689532.

 

Punke MA, Friederich P. Amitriptyline is a potent blocker of human Kv1.1 and Kv7.2/7.3 channels. Anesth Analg. 2007 May;104(5):1256-64. PMID: 17456683.

 

Owens MJ, Morgan WN, Plott SJ, et al. Neurotransmitter receptor and transporter binding profile of antidepressants and their metabolites. J Pharmacol Exp Ther. 1997 Dec;283(3):1305-22. PMID: 9400006.

 

Hamon M, Gozlan H, Bourgoin S, et al. Opioid receptors and neuropeptides in the CNS in rats treated chronically with amoxapine or amitriptyline. Neuropharmacology. 1987 Jun;26(6):531-9. PMID: 3037421.

" Xn, T+, Xi, Carc., "UN number: 2811     Class: 6.1     Packing Group: III

Proper shipping name: Toxic solids, organic, n.o.s. (Amitriptyline hydrochloride)

Marine pollutant: No     Poison Inhalation Hazard: No"

LKT A5272 Angiotensin, dog/rat 5 mg 83.9 Peptide, derivative of AT I, cleavage product of angiotensin, precursor to AT II. ≥95% 1296.51 C41H62N12O11 Ambient -20°C Soluble in water "Moon JY. Recent Update of Renin-angiotensin-aldosterone System in the Pathogenesis of Hypertension. Electrolyte Blood Press. 2013 Dec;11(2):41-45. PMID: 24627703.

 

Herichova I, Szantoova K. Renin-angiotensin system: upgrade of recent knowledge and perspectives. Endocr Regul. 2013 Jan;47(1):39-52. PMID: 23363256.

 

Dupont AG, Brouwers S. Brain angiotensin peptides regulate sympathetic tone and blood pressure. J Hypertens. 2010 Aug;28(8):1599-610. PMID: 20502352.

" "Not dangerous goods.

"

LKT A5272 Angiotensin, dog/rat 10 mg 144 Peptide, derivative of AT I, cleavage product of angiotensin, precursor to AT II. ≥95% 1296.51 C41H62N12O11 Ambient -20°C Soluble in water "Moon JY. Recent Update of Renin-angiotensin-aldosterone System in the Pathogenesis of Hypertension. Electrolyte Blood Press. 2013 Dec;11(2):41-45. PMID: 24627703.

 

Herichova I, Szantoova K. Renin-angiotensin system: upgrade of recent knowledge and perspectives. Endocr Regul. 2013 Jan;47(1):39-52. PMID: 23363256.

 

Dupont AG, Brouwers S. Brain angiotensin peptides regulate sympathetic tone and blood pressure. J Hypertens. 2010 Aug;28(8):1599-610. PMID: 20502352.

" "Not dangerous goods.

"

LKT A5272 Angiotensin, dog/rat 25 mg 252.1 Peptide, derivative of AT I, cleavage product of angiotensin, precursor to AT II. ≥95% 1296.51 C41H62N12O11 Ambient -20°C Soluble in water "Moon JY. Recent Update of Renin-angiotensin-aldosterone System in the Pathogenesis of Hypertension. Electrolyte Blood Press. 2013 Dec;11(2):41-45. PMID: 24627703.

 

Herichova I, Szantoova K. Renin-angiotensin system: upgrade of recent knowledge and perspectives. Endocr Regul. 2013 Jan;47(1):39-52. PMID: 23363256.

 

Dupont AG, Brouwers S. Brain angiotensin peptides regulate sympathetic tone and blood pressure. J Hypertens. 2010 Aug;28(8):1599-610. PMID: 20502352.

" "Not dangerous goods.

"

LKT A5273 Angiotensin Converting Enzyme Inhibitor Peptide 5 mg 48 Peptide; ACE inhibitor. ACE inhibitor peptide ≥95% 1102.29 C53H77N14O12 Ambient -20°C "Martins AR, Caldo H, Coelho HL, et al. Screening for rabbit brain neuropeptide-metabolizing peptidases. Inhibition of endopeptidase B by bradykinin potentiating peptide 9a (SQ 20881). J Neurochem. 1980 Jan;34(1):100-7. PMID: 6161209.

 

Oparil S, Koerner T, O'Donoghue JK. Mechanism of angiotensin I converting enzyme inhibition by SQ20,881 (less than Glu-Trp-Pro-Arg-Pro-Gln-Ile-Pro-Pro) in vivo. Further evidence for extrapulmonary conversion. Hypertension. 1979 Jan-Feb;1(1):13-22. PMID: 232489.

 

Vollmer RR, Boccagno JA, Harris DN, et al. Hypotension induced by inhibition of angiotensin-converting enzyme in pentobarbital-anesthetized dogs. Eur J Pharmacol. 1978 Sep 1;51(1):39-45. PMID: 212276.

" Not dangerous goods.

LKT A5273 Angiotensin Converting Enzyme Inhibitor Peptide 10 mg 81 Peptide; ACE inhibitor. ACE inhibitor peptide ≥95% 1102.29 C53H77N14O12 Ambient -20°C "Martins AR, Caldo H, Coelho HL, et al. Screening for rabbit brain neuropeptide-metabolizing peptidases. Inhibition of endopeptidase B by bradykinin potentiating peptide 9a (SQ 20881). J Neurochem. 1980 Jan;34(1):100-7. PMID: 6161209.

 

Oparil S, Koerner T, O'Donoghue JK. Mechanism of angiotensin I converting enzyme inhibition by SQ20,881 (less than Glu-Trp-Pro-Arg-Pro-Gln-Ile-Pro-Pro) in vivo. Further evidence for extrapulmonary conversion. Hypertension. 1979 Jan-Feb;1(1):13-22. PMID: 232489.

 

Vollmer RR, Boccagno JA, Harris DN, et al. Hypotension induced by inhibition of angiotensin-converting enzyme in pentobarbital-anesthetized dogs. Eur J Pharmacol. 1978 Sep 1;51(1):39-45. PMID: 212276.

" Not dangerous goods.

LKT A5273 Angiotensin Converting Enzyme Inhibitor Peptide 25 mg 144 Peptide; ACE inhibitor. ACE inhibitor peptide ≥95% 1102.29 C53H77N14O12 Ambient -20°C "Martins AR, Caldo H, Coelho HL, et al. Screening for rabbit brain neuropeptide-metabolizing peptidases. Inhibition of endopeptidase B by bradykinin potentiating peptide 9a (SQ 20881). J Neurochem. 1980 Jan;34(1):100-7. PMID: 6161209.

 

Oparil S, Koerner T, O'Donoghue JK. Mechanism of angiotensin I converting enzyme inhibition by SQ20,881 (less than Glu-Trp-Pro-Arg-Pro-Gln-Ile-Pro-Pro) in vivo. Further evidence for extrapulmonary conversion. Hypertension. 1979 Jan-Feb;1(1):13-22. PMID: 232489.

 

Vollmer RR, Boccagno JA, Harris DN, et al. Hypotension induced by inhibition of angiotensin-converting enzyme in pentobarbital-anesthetized dogs. Eur J Pharmacol. 1978 Sep 1;51(1):39-45. PMID: 212276.

" Not dangerous goods.

LKT A5275 [Des-Asp1]-Angiotensin I, human 5 mg 36 Peptide, derivative of AT I, cleavage product of angiotensin, precursor to AT II. ≥95% 1181.42 C58H84N16O11 Ambient -20°C Gonzalez-Villalobos RA, Shen XZ, Bernstein EA, et al. Rediscovering ACE: novel insights into the many roles of the angiotensin-converting enzyme. J Mol Med (Berl). 2013 Oct;91(10):1143-54. PMID: 23686164.

LKT A5275 [Des-Asp1]-Angiotensin I, human 10 mg 60 Peptide, derivative of AT I, cleavage product of angiotensin, precursor to AT II. ≥95% 1181.42 C58H84N16O11 Ambient -20°C Gonzalez-Villalobos RA, Shen XZ, Bernstein EA, et al. Rediscovering ACE: novel insights into the many roles of the angiotensin-converting enzyme. J Mol Med (Berl). 2013 Oct;91(10):1143-54. PMID: 23686164.

LKT A5275 [Des-Asp1]-Angiotensin I, human 25 mg 107.8 Peptide, derivative of AT I, cleavage product of angiotensin, precursor to AT II. ≥95% 1181.42 C58H84N16O11 Ambient -20°C Gonzalez-Villalobos RA, Shen XZ, Bernstein EA, et al. Rediscovering ACE: novel insights into the many roles of the angiotensin-converting enzyme. J Mol Med (Berl). 2013 Oct;91(10):1143-54. PMID: 23686164.

LKT A5276 Angiotensin I, human 5 mg 36 Endogenous peptide, cleavage product of angiotensin, precursor to angiotensin II. Hypertensin I 70937-97-2 ≥98% 1296.49 C62H89N17O14 Ambient -20°C Soluble in physiological saline. Gonzalez-Villalobos RA, Shen XZ, Bernstein EA, et al. Rediscovering ACE: novel insights into the many roles of the angiotensin-converting enzyme. J Mol Med (Berl). 2013 Oct;91(10):1143-54. PMID: 23686164. Not dangerous goods.

LKT A5276 Angiotensin I, human 10 mg 60 Endogenous peptide, cleavage product of angiotensin, precursor to angiotensin II. Hypertensin I 70937-97-2 ≥98% 1296.49 C62H89N17O14 Ambient -20°C Soluble in physiological saline. Gonzalez-Villalobos RA, Shen XZ, Bernstein EA, et al. Rediscovering ACE: novel insights into the many roles of the angiotensin-converting enzyme. J Mol Med (Berl). 2013 Oct;91(10):1143-54. PMID: 23686164. Not dangerous goods.

LKT A5276 Angiotensin I, human 25 mg 107.8 Endogenous peptide, cleavage product of angiotensin, precursor to angiotensin II. Hypertensin I 70937-97-2 ≥98% 1296.49 C62H89N17O14 Ambient -20°C Soluble in physiological saline. Gonzalez-Villalobos RA, Shen XZ, Bernstein EA, et al. Rediscovering ACE: novel insights into the many roles of the angiotensin-converting enzyme. J Mol Med (Berl). 2013 Oct;91(10):1143-54. PMID: 23686164. Not dangerous goods.

LKT A5277 Angiotensin II, human 5 mg 60 Endogenous peptide, involved in vasoconstriction, Na+ reabsorption, and blood pressure; AT1 agonist, Na+/H+ transporter activator. Hypertensin II 68521-88-0 ≥95% 1046.19 C50H71N13O12 CCC(C)C(C(=O)NC(CC1=CN=CN1)C(=O)N2CCCC2C(=O)NC(CC3=CC=CC=C3)C(=O)O)NC(=O)C(CC4=CC=C(C=C4)O)NC(=O)C(C(C)C)NC(=O)C(CCCN=C(N)N)NC(=O)C(CC(=O)O)N.CC(=O)O Ambient -20°C Soluble in water or 5% acetic acid. "De Giusti VC, Ciancio MC, Orlowski A, et al. Modulation of the cardiac sodium/bicarbonate cotransporter by the renin angiotensin aldosterone system: pathophysiological consequences. Front Physiol. 2014 Jan 17;4:411. PMID: 24478712.

 

Moon JY. Recent Update of Renin-angiotensin-aldosterone System in the Pathogenesis of Hypertension. Electrolyte Blood Press. 2013 Dec;11(2):41-45. PMID: 24627703." Not dangerous goods.

LKT A5277 Angiotensin II, human 10 mg 101.9 Endogenous peptide, involved in vasoconstriction, Na+ reabsorption, and blood pressure; AT1 agonist, Na+/H+ transporter activator. Hypertensin II 68521-88-0 ≥95% 1046.19 C50H71N13O12 CCC(C)C(C(=O)NC(CC1=CN=CN1)C(=O)N2CCCC2C(=O)NC(CC3=CC=CC=C3)C(=O)O)NC(=O)C(CC4=CC=C(C=C4)O)NC(=O)C(C(C)C)NC(=O)C(CCCN=C(N)N)NC(=O)C(CC(=O)O)N.CC(=O)O Ambient -20°C Soluble in water or 5% acetic acid. "De Giusti VC, Ciancio MC, Orlowski A, et al. Modulation of the cardiac sodium/bicarbonate cotransporter by the renin angiotensin aldosterone system: pathophysiological consequences. Front Physiol. 2014 Jan 17;4:411. PMID: 24478712.

 

Moon JY. Recent Update of Renin-angiotensin-aldosterone System in the Pathogenesis of Hypertension. Electrolyte Blood Press. 2013 Dec;11(2):41-45. PMID: 24627703." Not dangerous goods.

LKT A5277 Angiotensin II, human 25 mg 180 Endogenous peptide, involved in vasoconstriction, Na+ reabsorption, and blood pressure; AT1 agonist, Na+/H+ transporter activator. Hypertensin II 68521-88-0 ≥95% 1046.19 C50H71N13O12 CCC(C)C(C(=O)NC(CC1=CN=CN1)C(=O)N2CCCC2C(=O)NC(CC3=CC=CC=C3)C(=O)O)NC(=O)C(CC4=CC=C(C=C4)O)NC(=O)C(C(C)C)NC(=O)C(CCCN=C(N)N)NC(=O)C(CC(=O)O)N.CC(=O)O Ambient -20°C Soluble in water or 5% acetic acid. "De Giusti VC, Ciancio MC, Orlowski A, et al. Modulation of the cardiac sodium/bicarbonate cotransporter by the renin angiotensin aldosterone system: pathophysiological consequences. Front Physiol. 2014 Jan 17;4:411. PMID: 24478712.

 

Moon JY. Recent Update of Renin-angiotensin-aldosterone System in the Pathogenesis of Hypertension. Electrolyte Blood Press. 2013 Dec;11(2):41-45. PMID: 24627703." Not dangerous goods.

LKT A5278 Angiotensin III, human 5 mg 60 Endogenous peptide, cleavage product of AT II; AT1 agonist. 12687-51-3 ≥98% 931.1 C46H66N12O9 CCC(C)C(C(=O)NC(CC1=CN=CN1)C(=O)N2CCCC2C(=O)NC(CC3=CC=CC=C3)C(=O)O)NC(=O)C(CC4=CC=C(C=C4)O)NC(=O)C(C(C)C)NC(=O)C(CCCN=C(N)N)N Ambient -20°C Soluble in 5% acetic acid or in water (1 mg/mL). "Yugandhar VG, Clark MA. Angiotensin III: a physiological relevant peptide of the renin angiotensin system. Peptides. 2013 Aug;46:26-32. PMID: 23692861.

 

Yang R, Smolders I, Dupont AG. Blood pressure and renal hemodynamic effects of angiotensin fragments. Hypertens Res. 2011 Jun;34(6):674-83. PMID: 21412242.

 

Dupont AG, Brouwers S. Brain angiotensin peptides regulate sympathetic tone and blood pressure. J Hypertens. 2010 Aug;28(8):1599-610. PMID: 20502352.

" Not dangerous goods.

LKT A5278 Angiotensin III, human 10 mg 101.9 Endogenous peptide, cleavage product of AT II; AT1 agonist. 12687-51-3 ≥98% 931.1 C46H66N12O9 CCC(C)C(C(=O)NC(CC1=CN=CN1)C(=O)N2CCCC2C(=O)NC(CC3=CC=CC=C3)C(=O)O)NC(=O)C(CC4=CC=C(C=C4)O)NC(=O)C(C(C)C)NC(=O)C(CCCN=C(N)N)N Ambient -20°C Soluble in 5% acetic acid or in water (1 mg/mL). "Yugandhar VG, Clark MA. Angiotensin III: a physiological relevant peptide of the renin angiotensin system. Peptides. 2013 Aug;46:26-32. PMID: 23692861.

 

Yang R, Smolders I, Dupont AG. Blood pressure and renal hemodynamic effects of angiotensin fragments. Hypertens Res. 2011 Jun;34(6):674-83. PMID: 21412242.

 

Dupont AG, Brouwers S. Brain angiotensin peptides regulate sympathetic tone and blood pressure. J Hypertens. 2010 Aug;28(8):1599-610. PMID: 20502352.

" Not dangerous goods.

LKT A5278 Angiotensin III, human 25 mg 180 Endogenous peptide, cleavage product of AT II; AT1 agonist. 12687-51-3 ≥98% 931.1 C46H66N12O9 CCC(C)C(C(=O)NC(CC1=CN=CN1)C(=O)N2CCCC2C(=O)NC(CC3=CC=CC=C3)C(=O)O)NC(=O)C(CC4=CC=C(C=C4)O)NC(=O)C(C(C)C)NC(=O)C(CCCN=C(N)N)N Ambient -20°C Soluble in 5% acetic acid or in water (1 mg/mL). "Yugandhar VG, Clark MA. Angiotensin III: a physiological relevant peptide of the renin angiotensin system. Peptides. 2013 Aug;46:26-32. PMID: 23692861.

 

Yang R, Smolders I, Dupont AG. Blood pressure and renal hemodynamic effects of angiotensin fragments. Hypertens Res. 2011 Jun;34(6):674-83. PMID: 21412242.

 

Dupont AG, Brouwers S. Brain angiotensin peptides regulate sympathetic tone and blood pressure. J Hypertens. 2010 Aug;28(8):1599-610. PMID: 20502352.

" Not dangerous goods.

LKT A5279 Angiotensin II (1-4), human 5 mg 60 Endogenous peptide fragment, involved in vasoconstriction, Na+ reabsorption, and blood pressure; AT1 agonist, Na+/H+ transporter activator. ≥95% 551.6 C24H37N7O8 Ambient -20°C "De Giusti VC, Ciancio MC, Orlowski A, et al. Modulation of the cardiac sodium/bicarbonate cotransporter by the renin angiotensin aldosterone system: pathophysiological consequences. Front Physiol. 2014 Jan 17;4:411. PMID: 24478712.

 

Moon JY. Recent Update of Renin-angiotensin-aldosterone System in the Pathogenesis of Hypertension. Electrolyte Blood Press. 2013 Dec;11(2):41-45. PMID: 24627703.

" Not dangerous goods.

LKT A5279 Angiotensin II (1-4), human 10 mg 101.9 Endogenous peptide fragment, involved in vasoconstriction, Na+ reabsorption, and blood pressure; AT1 agonist, Na+/H+ transporter activator. ≥95% 551.6 C24H37N7O8 Ambient -20°C "De Giusti VC, Ciancio MC, Orlowski A, et al. Modulation of the cardiac sodium/bicarbonate cotransporter by the renin angiotensin aldosterone system: pathophysiological consequences. Front Physiol. 2014 Jan 17;4:411. PMID: 24478712.

 

Moon JY. Recent Update of Renin-angiotensin-aldosterone System in the Pathogenesis of Hypertension. Electrolyte Blood Press. 2013 Dec;11(2):41-45. PMID: 24627703.

" Not dangerous goods.

LKT A5279 Angiotensin II (1-4), human 25 mg 180 Endogenous peptide fragment, involved in vasoconstriction, Na+ reabsorption, and blood pressure; AT1 agonist, Na+/H+ transporter activator. ≥95% 551.6 C24H37N7O8 Ambient -20°C "De Giusti VC, Ciancio MC, Orlowski A, et al. Modulation of the cardiac sodium/bicarbonate cotransporter by the renin angiotensin aldosterone system: pathophysiological consequences. Front Physiol. 2014 Jan 17;4:411. PMID: 24478712.

 

Moon JY. Recent Update of Renin-angiotensin-aldosterone System in the Pathogenesis of Hypertension. Electrolyte Blood Press. 2013 Dec;11(2):41-45. PMID: 24627703.

" Not dangerous goods.

LKT A5280 Angiotensin II (3-8), human 5 mg 60 Endogenous peptide fragment, involved in vasoconstriction, Na+ reabsorption, and blood pressure; AT1 agonist, Na+/H+ transporter activator. 23025-68-5 ≥95% 774.93 C40H54N8O8 CCC(C)C(C(=O)NC(CC1=CN=CN1)C(=O)N2CCCC2C(=O)NC(CC3=CC=CC=C3)C(=O)O)NC(=O)C(CC4=CC=C(C=C4)O)NC(=O)C(C(C)C)N Ambient -20°C "De Giusti VC, Ciancio MC, Orlowski A, et al. Modulation of the cardiac sodium/bicarbonate cotransporter by the renin angiotensin aldosterone system: pathophysiological consequences. Front Physiol. 2014 Jan 17;4:411. PMID: 24478712.

 

Moon JY. Recent Update of Renin-angiotensin-aldosterone System in the Pathogenesis of Hypertension. Electrolyte Blood Press. 2013 Dec;11(2):41-45. PMID: 24627703.

" Not dangerous goods.

LKT A5280 Angiotensin II (3-8), human 10 mg 101.9 Endogenous peptide fragment, involved in vasoconstriction, Na+ reabsorption, and blood pressure; AT1 agonist, Na+/H+ transporter activator. 23025-68-5 ≥95% 774.93 C40H54N8O8 CCC(C)C(C(=O)NC(CC1=CN=CN1)C(=O)N2CCCC2C(=O)NC(CC3=CC=CC=C3)C(=O)O)NC(=O)C(CC4=CC=C(C=C4)O)NC(=O)C(C(C)C)N Ambient -20°C "De Giusti VC, Ciancio MC, Orlowski A, et al. Modulation of the cardiac sodium/bicarbonate cotransporter by the renin angiotensin aldosterone system: pathophysiological consequences. Front Physiol. 2014 Jan 17;4:411. PMID: 24478712.

 

Moon JY. Recent Update of Renin-angiotensin-aldosterone System in the Pathogenesis of Hypertension. Electrolyte Blood Press. 2013 Dec;11(2):41-45. PMID: 24627703.

" Not dangerous goods.

LKT A5280 Angiotensin II (3-8), human 25 mg 180 Endogenous peptide fragment, involved in vasoconstriction, Na+ reabsorption, and blood pressure; AT1 agonist, Na+/H+ transporter activator. 23025-68-5 ≥95% 774.93 C40H54N8O8 CCC(C)C(C(=O)NC(CC1=CN=CN1)C(=O)N2CCCC2C(=O)NC(CC3=CC=CC=C3)C(=O)O)NC(=O)C(CC4=CC=C(C=C4)O)NC(=O)C(C(C)C)N Ambient -20°C "De Giusti VC, Ciancio MC, Orlowski A, et al. Modulation of the cardiac sodium/bicarbonate cotransporter by the renin angiotensin aldosterone system: pathophysiological consequences. Front Physiol. 2014 Jan 17;4:411. PMID: 24478712.

 

Moon JY. Recent Update of Renin-angiotensin-aldosterone System in the Pathogenesis of Hypertension. Electrolyte Blood Press. 2013 Dec;11(2):41-45. PMID: 24627703.

" Not dangerous goods.

LKT A5281 Angiotensin II (4-8), human 5 mg 60 Endogenous peptide fragment, involved in vasoconstriction, Na+ reabsorption, and blood pressure; AT1 agonist, Na+/H+ transporter activator. ≥95% 675.79 C35H45N7O7 Ambient -20°C Not dangerous goods.

LKT A5281 Angiotensin II (4-8), human 10 mg 101.9 Endogenous peptide fragment, involved in vasoconstriction, Na+ reabsorption, and blood pressure; AT1 agonist, Na+/H+ transporter activator. ≥95% 675.79 C35H45N7O7 Ambient -20°C Not dangerous goods.

LKT A5281 Angiotensin II (4-8), human 25 mg 180 Endogenous peptide fragment, involved in vasoconstriction, Na+ reabsorption, and blood pressure; AT1 agonist, Na+/H+ transporter activator. ≥95% 675.79 C35H45N7O7 Ambient -20°C Not dangerous goods.

LKT A5282 [Sar1 Ile8]-Angiotensin II 5 mg 60 Peptide, derivative of AT II, involved in vasoconstriction, Na+ reabsorption, and blood pressure; AT1 agonist, Na+/H+ transporter activator. 67724-27-0 ≥95% 968.1 C46H74N13O10 CCC(C)C(C(=O)NC(CC1=CN=CN1)C(=O)N2CCCC2C(=O)NC(C(C)CC)C(=O)O)NC(=O)C(CC3=CC=C(C=C3)O)NC(=O)C(C(C)C)NC(=O)C(CCCN=C(N)N)NC(=O)CNC Ambient -20°C "De Giusti VC, Ciancio MC, Orlowski A, et al. Modulation of the cardiac sodium/bicarbonate cotransporter by the renin angiotensin aldosterone system: pathophysiological consequences. Front Physiol. 2014 Jan 17;4:411. PMID: 24478712.

 

Moon JY. Recent Update of Renin-angiotensin-aldosterone System in the Pathogenesis of Hypertension. Electrolyte Blood Press. 2013 Dec;11(2):41-45. PMID: 24627703.

" Not dangerous goods.

LKT A5282 [Sar1 Ile8]-Angiotensin II 10 mg 101.9 Peptide, derivative of AT II, involved in vasoconstriction, Na+ reabsorption, and blood pressure; AT1 agonist, Na+/H+ transporter activator. 67724-27-0 ≥95% 968.1 C46H74N13O10 CCC(C)C(C(=O)NC(CC1=CN=CN1)C(=O)N2CCCC2C(=O)NC(C(C)CC)C(=O)O)NC(=O)C(CC3=CC=C(C=C3)O)NC(=O)C(C(C)C)NC(=O)C(CCCN=C(N)N)NC(=O)CNC Ambient -20°C "De Giusti VC, Ciancio MC, Orlowski A, et al. Modulation of the cardiac sodium/bicarbonate cotransporter by the renin angiotensin aldosterone system: pathophysiological consequences. Front Physiol. 2014 Jan 17;4:411. PMID: 24478712.

 

Moon JY. Recent Update of Renin-angiotensin-aldosterone System in the Pathogenesis of Hypertension. Electrolyte Blood Press. 2013 Dec;11(2):41-45. PMID: 24627703.

" Not dangerous goods.

LKT A5282 [Sar1 Ile8]-Angiotensin II 25 mg 180 Peptide, derivative of AT II, involved in vasoconstriction, Na+ reabsorption, and blood pressure; AT1 agonist, Na+/H+ transporter activator. 67724-27-0 ≥95% 968.1 C46H74N13O10 CCC(C)C(C(=O)NC(CC1=CN=CN1)C(=O)N2CCCC2C(=O)NC(C(C)CC)C(=O)O)NC(=O)C(CC3=CC=C(C=C3)O)NC(=O)C(C(C)C)NC(=O)C(CCCN=C(N)N)NC(=O)CNC Ambient -20°C "De Giusti VC, Ciancio MC, Orlowski A, et al. Modulation of the cardiac sodium/bicarbonate cotransporter by the renin angiotensin aldosterone system: pathophysiological consequences. Front Physiol. 2014 Jan 17;4:411. PMID: 24478712.

 

Moon JY. Recent Update of Renin-angiotensin-aldosterone System in the Pathogenesis of Hypertension. Electrolyte Blood Press. 2013 Dec;11(2):41-45. PMID: 24627703.

" Not dangerous goods.

LKT A5283 [Sar1]-Angiotensin II 5 mg 60 Peptide, derivative of AT II, involved in vasoconstriction, Na+ reabsorption, and blood pressure; AT1 agonist, Na+/H+ transporter activator. ≥95% 1018.19 C49H71N13O11 Ambient -20°C "De Giusti VC, Ciancio MC, Orlowski A, et al. Modulation of the cardiac sodium/bicarbonate cotransporter by the renin angiotensin aldosterone system: pathophysiological consequences. Front Physiol. 2014 Jan 17;4:411. PMID: 24478712.

 

Moon JY. Recent Update of Renin-angiotensin-aldosterone System in the Pathogenesis of Hypertension. Electrolyte Blood Press. 2013 Dec;11(2):41-45. PMID: 24627703.

" Not dangerous goods.

LKT A5283 [Sar1]-Angiotensin II 10 mg 101.9 Peptide, derivative of AT II, involved in vasoconstriction, Na+ reabsorption, and blood pressure; AT1 agonist, Na+/H+ transporter activator. ≥95% 1018.19 C49H71N13O11 Ambient -20°C "De Giusti VC, Ciancio MC, Orlowski A, et al. Modulation of the cardiac sodium/bicarbonate cotransporter by the renin angiotensin aldosterone system: pathophysiological consequences. Front Physiol. 2014 Jan 17;4:411. PMID: 24478712.

 

Moon JY. Recent Update of Renin-angiotensin-aldosterone System in the Pathogenesis of Hypertension. Electrolyte Blood Press. 2013 Dec;11(2):41-45. PMID: 24627703.

" Not dangerous goods.

LKT A5283 [Sar1]-Angiotensin II 25 mg 180 Peptide, derivative of AT II, involved in vasoconstriction, Na+ reabsorption, and blood pressure; AT1 agonist, Na+/H+ transporter activator. ≥95% 1018.19 C49H71N13O11 Ambient -20°C "De Giusti VC, Ciancio MC, Orlowski A, et al. Modulation of the cardiac sodium/bicarbonate cotransporter by the renin angiotensin aldosterone system: pathophysiological consequences. Front Physiol. 2014 Jan 17;4:411. PMID: 24478712.

 

Moon JY. Recent Update of Renin-angiotensin-aldosterone System in the Pathogenesis of Hypertension. Electrolyte Blood Press. 2013 Dec;11(2):41-45. PMID: 24627703.

" Not dangerous goods.

LKT A5284 [Val5]-Angiotensin II, human 5 mg 60 Peptide, derivative of AT II, involved in vasoconstriction, Na+ reabsorption, and blood pressure; AT1 agonist, Na+/H+ transporter activator. ≥95% 1032.18 C49H69N13O12 Ambient -20°C "De Giusti VC, Ciancio MC, Orlowski A, et al. Modulation of the cardiac sodium/bicarbonate cotransporter by the renin angiotensin aldosterone system: pathophysiological consequences. Front Physiol. 2014 Jan 17;4:411. PMID: 24478712.

 

Moon JY. Recent Update of Renin-angiotensin-aldosterone System in the Pathogenesis of Hypertension. Electrolyte Blood Press. 2013 Dec;11(2):41-45. PMID: 24627703.

" Not dangerous goods.

LKT A5284 [Val5]-Angiotensin II, human 10 mg 101.9 Peptide, derivative of AT II, involved in vasoconstriction, Na+ reabsorption, and blood pressure; AT1 agonist, Na+/H+ transporter activator. ≥95% 1032.18 C49H69N13O12 Ambient -20°C "De Giusti VC, Ciancio MC, Orlowski A, et al. Modulation of the cardiac sodium/bicarbonate cotransporter by the renin angiotensin aldosterone system: pathophysiological consequences. Front Physiol. 2014 Jan 17;4:411. PMID: 24478712.

 

Moon JY. Recent Update of Renin-angiotensin-aldosterone System in the Pathogenesis of Hypertension. Electrolyte Blood Press. 2013 Dec;11(2):41-45. PMID: 24627703.

" Not dangerous goods.

LKT A5284 [Val5]-Angiotensin II, human 25 mg 180 Peptide, derivative of AT II, involved in vasoconstriction, Na+ reabsorption, and blood pressure; AT1 agonist, Na+/H+ transporter activator. ≥95% 1032.18 C49H69N13O12 Ambient -20°C "De Giusti VC, Ciancio MC, Orlowski A, et al. Modulation of the cardiac sodium/bicarbonate cotransporter by the renin angiotensin aldosterone system: pathophysiological consequences. Front Physiol. 2014 Jan 17;4:411. PMID: 24478712.

 

Moon JY. Recent Update of Renin-angiotensin-aldosterone System in the Pathogenesis of Hypertension. Electrolyte Blood Press. 2013 Dec;11(2):41-45. PMID: 24627703.

" Not dangerous goods.

LKT A5285 [Ile7]-Angiotensin III 1 mg 60 Peptide, derivative of AT III, cleavage product of AT II; AT1 agonist. ≥95% 897.1 C43H68N12O9 Ambient -20°C "Yugandhar VG, Clark MA. Angiotensin III: a physiological relevant peptide of the renin angiotensin system. Peptides. 2013 Aug;46:26-32. PMID: 23692861.

 

Yang R, Smolders I, Dupont AG. Blood pressure and renal hemodynamic effects of angiotensin fragments. Hypertens Res. 2011 Jun;34(6):674-83. PMID: 21412242.

 

Dupont AG, Brouwers S. Brain angiotensin peptides regulate sympathetic tone and blood pressure. J Hypertens. 2010 Aug;28(8):1599-610. PMID: 20502352.

" Not dangerous goods.

LKT A5285 [Ile7]-Angiotensin III 2 mg 101.9 Peptide, derivative of AT III, cleavage product of AT II; AT1 agonist. ≥95% 897.1 C43H68N12O9 Ambient -20°C "Yugandhar VG, Clark MA. Angiotensin III: a physiological relevant peptide of the renin angiotensin system. Peptides. 2013 Aug;46:26-32. PMID: 23692861.

 

Yang R, Smolders I, Dupont AG. Blood pressure and renal hemodynamic effects of angiotensin fragments. Hypertens Res. 2011 Jun;34(6):674-83. PMID: 21412242.

 

Dupont AG, Brouwers S. Brain angiotensin peptides regulate sympathetic tone and blood pressure. J Hypertens. 2010 Aug;28(8):1599-610. PMID: 20502352.

" Not dangerous goods.

LKT A5285 [Ile7]-Angiotensin III 5 mg 180 Peptide, derivative of AT III, cleavage product of AT II; AT1 agonist. ≥95% 897.1 C43H68N12O9 Ambient -20°C "Yugandhar VG, Clark MA. Angiotensin III: a physiological relevant peptide of the renin angiotensin system. Peptides. 2013 Aug;46:26-32. PMID: 23692861.

 

Yang R, Smolders I, Dupont AG. Blood pressure and renal hemodynamic effects of angiotensin fragments. Hypertens Res. 2011 Jun;34(6):674-83. PMID: 21412242.

 

Dupont AG, Brouwers S. Brain angiotensin peptides regulate sympathetic tone and blood pressure. J Hypertens. 2010 Aug;28(8):1599-610. PMID: 20502352.

" Not dangerous goods.

LKT A5287 Angiotensinogen (1-14), human 1 mg 60 Peptide fragment, renin substrate, precursor to AT I. ≥95% 1760.05 C83H122N24O19 Ambient -20°C "Herichova I, Szantoova K. Renin-angiotensin system: upgrade of recent knowledge and perspectives. Endocr Regul. 2013 Jan;47(1):39-52. PMID: 23363256.

 

Kobori H, Urushihara M. Augmented intrarenal and urinary angiotensinogen in hypertension and chronic kidney disease. Pflugers Arch. 2013 Jan;465(1):3-12. PMID: 22918624.

" Not dangerous goods.

LKT A5287 Angiotensinogen (1-14), human 2 mg 101.9 Peptide fragment, renin substrate, precursor to AT I. ≥95% 1760.05 C83H122N24O19 Ambient -20°C "Herichova I, Szantoova K. Renin-angiotensin system: upgrade of recent knowledge and perspectives. Endocr Regul. 2013 Jan;47(1):39-52. PMID: 23363256.

 

Kobori H, Urushihara M. Augmented intrarenal and urinary angiotensinogen in hypertension and chronic kidney disease. Pflugers Arch. 2013 Jan;465(1):3-12. PMID: 22918624.

" Not dangerous goods.

LKT A5287 Angiotensinogen (1-14), human 5 mg 180 Peptide fragment, renin substrate, precursor to AT I. ≥95% 1760.05 C83H122N24O19 Ambient -20°C "Herichova I, Szantoova K. Renin-angiotensin system: upgrade of recent knowledge and perspectives. Endocr Regul. 2013 Jan;47(1):39-52. PMID: 23363256.

 

Kobori H, Urushihara M. Augmented intrarenal and urinary angiotensinogen in hypertension and chronic kidney disease. Pflugers Arch. 2013 Jan;465(1):3-12. PMID: 22918624.

" Not dangerous goods.

LKT A5302 Anastrozole 100 mg 127.5 Aromatase inhibitor. 2,2'-(5-(IH-1,2,4-triazol-1-ylmethyl)-1,3-phenylene)bis(2-methylpropiononitrile) ZD1033 Pure, Zeneca ZD1033 120511-73-1 ≥99% 293.37 C17H19N5 CC(C)(C#N)C1=CC(=CC(=C1)CN2C=NC=N2)C(C)(C)C#N Ambient Ambient soluble in methanol, acetone, ethanol (59 mg/mL), THF, ethyl acetate, chloroform, DMSO (40 mg/mL).  Slightly soluble in water. "Kelly CM, Buzdar AU. Anastrozole. Expert Opin Drug Saf. 2010 Nov;9(6):995-1003. PMID: 20923259.

 

Hong Y, Chen S. Aromatase inhibitors: structural features and biochemical characterization. Ann N Y Acad Sci. 2006 Nov;1089:237-51. PMID: 17261771.

 

McCloskey E. Effects of third-generation aromatase inhibitors on bone. Eur J Cancer. 2006 May;42(8):1044-51. PMID: 16554149.

 

Xanthopoulos JM, Romano AE, Majumdar SK. Response of Mouse Breast Cancer Cells to Anastrozole, Tamoxifen, and the Combination. J Biomed Biotechnol. 2005;2005(1):10-19. PMID: 15689634.

" Xi Not dangerous goods.

LKT A5302 Anastrozole 250 mg 234.5 Aromatase inhibitor. 2,2'-(5-(IH-1,2,4-triazol-1-ylmethyl)-1,3-phenylene)bis(2-methylpropiononitrile) ZD1033 Pure, Zeneca ZD1033 120511-73-1 ≥99% 293.37 C17H19N5 CC(C)(C#N)C1=CC(=CC(=C1)CN2C=NC=N2)C(C)(C)C#N Ambient Ambient soluble in methanol, acetone, ethanol (59 mg/mL), THF, ethyl acetate, chloroform, DMSO (40 mg/mL).  Slightly soluble in water. "Kelly CM, Buzdar AU. Anastrozole. Expert Opin Drug Saf. 2010 Nov;9(6):995-1003. PMID: 20923259.

 

Hong Y, Chen S. Aromatase inhibitors: structural features and biochemical characterization. Ann N Y Acad Sci. 2006 Nov;1089:237-51. PMID: 17261771.

 

McCloskey E. Effects of third-generation aromatase inhibitors on bone. Eur J Cancer. 2006 May;42(8):1044-51. PMID: 16554149.

 

Xanthopoulos JM, Romano AE, Majumdar SK. Response of Mouse Breast Cancer Cells to Anastrozole, Tamoxifen, and the Combination. J Biomed Biotechnol. 2005;2005(1):10-19. PMID: 15689634.

" Xi Not dangerous goods.

LKT A5302 Anastrozole 1 g 712.6 Aromatase inhibitor. 2,2'-(5-(IH-1,2,4-triazol-1-ylmethyl)-1,3-phenylene)bis(2-methylpropiononitrile) ZD1033 Pure, Zeneca ZD1033 120511-73-1 ≥99% 293.37 C17H19N5 CC(C)(C#N)C1=CC(=CC(=C1)CN2C=NC=N2)C(C)(C)C#N Ambient Ambient soluble in methanol, acetone, ethanol (59 mg/mL), THF, ethyl acetate, chloroform, DMSO (40 mg/mL).  Slightly soluble in water. "Kelly CM, Buzdar AU. Anastrozole. Expert Opin Drug Saf. 2010 Nov;9(6):995-1003. PMID: 20923259.

 

Hong Y, Chen S. Aromatase inhibitors: structural features and biochemical characterization. Ann N Y Acad Sci. 2006 Nov;1089:237-51. PMID: 17261771.

 

McCloskey E. Effects of third-generation aromatase inhibitors on bone. Eur J Cancer. 2006 May;42(8):1044-51. PMID: 16554149.

 

Xanthopoulos JM, Romano AE, Majumdar SK. Response of Mouse Breast Cancer Cells to Anastrozole, Tamoxifen, and the Combination. J Biomed Biotechnol. 2005;2005(1):10-19. PMID: 15689634.

" Xi Not dangerous goods.

LKT A5313 Andrographolide 10 mg 25.2 Labdane diterpene found in Andrographis; RLR (RIG1-like) antagonist. [1R-[1α[E(S*)],4ab,5α,6α,8aα]]-3-[2-[Decahydro-6- hydroxy-5-(hydroxymethyl)-5,8a-dimethyl-2- methylene-1-naphthalenyl]ethylidene]dihydro-4- hydroxy-2(3H)-furanone Andrographis 5508-58-7 ≥98% 350.45 C20H30O5 CC12CCC(C(C1CCC(=C)C2CC=C3C(COC3=O)O)(C)CO)O Ambient -20°C Soluble in methanol, acetone, chloroform or ether. Slightly soluble in water. "Lu CY, Yang YC, Li CC, et al. Andrographolide inhibits TNFα-induced ICAM-1 expression via suppression of NADPH oxidase activation and induction of HO-1 and GCLM expression through the PI3K/Akt/Nrf2 and PI3K/Akt/AP-1 pathways in human endothelial cells. Biochem Pharmacol. 2014 Sep 1;91(1):40-50. PMID: 24998495.

 

Yu B, Dai CQ, Jiang ZY, et al. Andrographolide as an anti-H1N1 drug and the mechanism related to retinoic acid-inducible gene-I-like receptors signaling pathway. Chin J Integr Med. 2014 Jul;20(7):540-5. PMID: 24972581.

 

Wang J, Tan XF, Nguyen VS, et al. A quantitative chemical proteomics approach to profile the specific cellular targets of andrographolide, a promising anticancer agent that suppresses tumor metastasis. Mol Cell Proteomics. 2014 Mar;13(3):876-86. PMID: 24445406.

 

Liu SH, Lin CH, Liang FP, et al. Andrographolide downregulates the v-Src and Bcr-Abl oncoproteins and induces Hsp90 cleavage in the ROS-dependent suppression of cancer malignancy. Biochem Pharmacol. 2014 Jan 15;87(2):229-42. PMID: 24161787.

 

Shen T, Yang WS, Yi YS, et al. AP-1/IRF-3 Targeted Anti-Inflammatory Activity of Andrographolide Isolated from Andrographis paniculata. Evid Based Complement Alternat Med. 2013;2013:210736. PMID: 23840248.

 

Zhang C, Gui L, Xu Y, et al. Preventive effects of andrographolide on the development of diabetes in autoimmune diabetic NOD mice by inducing immune tolerance. Int Immunopharmacol. 2013 Aug;16(4):451-6. PMID: 23707775.

" None Not dangerous goods.

LKT A5314 Dehydroandrographolide 1 mg 115.4 Labdane diterpene found in Andrographis. ≥98% 332.43 C20H28O4         -20°C Soluble in chloroform "Chen H, Ma YB, Huang XY, et al. Synthesis, structure-activity relationships and biological evaluation of dehydroandrographolide and andrographolide derivatives as novel anti-hepatitis B virus agents. Bioorg Med Chem Lett. 2014 May 15;24(10):2353-9. PMID: 24731274.

 

Zhu T, Guan X, Zhang W, et al. Dehydroandrographolide succinate inhibits oxidative stress in mice with lipopolysaccharide-induced acute lung injury by inactivating iNOS. Nan Fang Yi Ke Da Xue Xue Bao. 2012 Sep;32(9):1238-41. PMID: 22985554.

" Not dangerous goods.

LKT A5314 Dehydroandrographolide 5 mg 418.3 Labdane diterpene found in Andrographis. ≥98% 332.43 C20H28O4         -20°C Soluble in chloroform "Chen H, Ma YB, Huang XY, et al. Synthesis, structure-activity relationships and biological evaluation of dehydroandrographolide and andrographolide derivatives as novel anti-hepatitis B virus agents. Bioorg Med Chem Lett. 2014 May 15;24(10):2353-9. PMID: 24731274.

 

Zhu T, Guan X, Zhang W, et al. Dehydroandrographolide succinate inhibits oxidative stress in mice with lipopolysaccharide-induced acute lung injury by inactivating iNOS. Nan Fang Yi Ke Da Xue Xue Bao. 2012 Sep;32(9):1238-41. PMID: 22985554.

" Not dangerous goods.

LKT A5314 Dehydroandrographolide 10 mg 610.9 Labdane diterpene found in Andrographis. ≥98% 332.43 C20H28O4         -20°C Soluble in chloroform "Chen H, Ma YB, Huang XY, et al. Synthesis, structure-activity relationships and biological evaluation of dehydroandrographolide and andrographolide derivatives as novel anti-hepatitis B virus agents. Bioorg Med Chem Lett. 2014 May 15;24(10):2353-9. PMID: 24731274.

 

Zhu T, Guan X, Zhang W, et al. Dehydroandrographolide succinate inhibits oxidative stress in mice with lipopolysaccharide-induced acute lung injury by inactivating iNOS. Nan Fang Yi Ke Da Xue Xue Bao. 2012 Sep;32(9):1238-41. PMID: 22985554.

" Not dangerous goods.

LKT A5315 Deoxyandrographolide 1 mg 67.9 Labdane diterpene found in Andrographolis; cNOS and adenylyl cyclase activator, PAF inhibitor, potential voltage-gated Ca2+ channel blocker. ≥98% 334.45 C20H30O4 Ambient -20°C "Mandal S, Nelson VK, Mukhopadhyay S, et al. 14-Deoxyandrographolide targets adenylate cyclase and prevents ethanol-induced liver injury through constitutive NOS dependent reduced redox signaling in rats. Food Chem Toxicol. 2013 Sep;59:236-48. PMID: 23764359.

 

Awang K, Abdullah NH, Hadi AH, et al. Cardiovascular activity of labdane diterpenes from Andrographis paniculata in isolated rat hearts. J Biomed Biotechnol. 2012;2012:876458. PMID: 22536026.

 

Burgos RA, Hidalgo MA, Monsalve J, et al. 14-deoxyandrographolide as a platelet activating factor antagonist in bovine neutrophils. Planta Med. 2005 Jul;71(7):604-8. PMID: 16041644.

 

Burgos RA, Loyola M, Hidalgo MA, et al. Effect of 14-deoxyandrographolide on calcium-mediated rat uterine smooth muscle contractility. Phytother Res. 2003 Nov;17(9):1011-5. PMID: 14595578.

" Not dangerous goods.

LKT A5315 Deoxyandrographolide 5 mg 237.8 Labdane diterpene found in Andrographolis; cNOS and adenylyl cyclase activator, PAF inhibitor, potential voltage-gated Ca2+ channel blocker. ≥98% 334.45 C20H30O4 Ambient -20°C "Mandal S, Nelson VK, Mukhopadhyay S, et al. 14-Deoxyandrographolide targets adenylate cyclase and prevents ethanol-induced liver injury through constitutive NOS dependent reduced redox signaling in rats. Food Chem Toxicol. 2013 Sep;59:236-48. PMID: 23764359.

 

Awang K, Abdullah NH, Hadi AH, et al. Cardiovascular activity of labdane diterpenes from Andrographis paniculata in isolated rat hearts. J Biomed Biotechnol. 2012;2012:876458. PMID: 22536026.

 

Burgos RA, Hidalgo MA, Monsalve J, et al. 14-deoxyandrographolide as a platelet activating factor antagonist in bovine neutrophils. Planta Med. 2005 Jul;71(7):604-8. PMID: 16041644.

 

Burgos RA, Loyola M, Hidalgo MA, et al. Effect of 14-deoxyandrographolide on calcium-mediated rat uterine smooth muscle contractility. Phytother Res. 2003 Nov;17(9):1011-5. PMID: 14595578.

" Not dangerous goods.

LKT A5315 Deoxyandrographolide 10 mg 305.9 Labdane diterpene found in Andrographolis; cNOS and adenylyl cyclase activator, PAF inhibitor, potential voltage-gated Ca2+ channel blocker. ≥98% 334.45 C20H30O4 Ambient -20°C "Mandal S, Nelson VK, Mukhopadhyay S, et al. 14-Deoxyandrographolide targets adenylate cyclase and prevents ethanol-induced liver injury through constitutive NOS dependent reduced redox signaling in rats. Food Chem Toxicol. 2013 Sep;59:236-48. PMID: 23764359.

 

Awang K, Abdullah NH, Hadi AH, et al. Cardiovascular activity of labdane diterpenes from Andrographis paniculata in isolated rat hearts. J Biomed Biotechnol. 2012;2012:876458. PMID: 22536026.

 

Burgos RA, Hidalgo MA, Monsalve J, et al. 14-deoxyandrographolide as a platelet activating factor antagonist in bovine neutrophils. Planta Med. 2005 Jul;71(7):604-8. PMID: 16041644.

 

Burgos RA, Loyola M, Hidalgo MA, et al. Effect of 14-deoxyandrographolide on calcium-mediated rat uterine smooth muscle contractility. Phytother Res. 2003 Nov;17(9):1011-5. PMID: 14595578.

" Not dangerous goods.

LKT A5326 Aniracetam 100 mg 104.3 AMPA positive allosteric modulator, D2, 5-HT2A, nAChR agonist. 1-(4-Methoxybenzoyl)-2-pyrrolidinone "Ro-13-5057; Draganon; Sarpul

 

" 72432-10-1 ≥98% 219.24 C12H13NO3 COC1=CC=C(C=C1)C(=O)N2CCCC2=O Ambient Ambient "Soluble in chloroform and ethyl acetate. Slightly soluble in ethanol. Insoluble in water.

" "Wang YF, Li CC, Cai JX. Aniracetam attenuates H2O2-induced deficiency of neuron viability, mitochondria potential and hippocampal long-term potentiation of mice in vitro. Neurosci Bull. 2006 Sep;22(5):274-80. PMID: 17690727.

 

Jin R, Clark S, Weeks AM, et al. Mechanism of positive allosteric modulators acting on AMPA receptors. J Neurosci. 2005 Sep 28;25(39):9027-36. PMID: 16192394.

 

Nakamura K. Aniracetam: its novel therapeutic potential in cerebral dysfunctional disorders based on recent pharmacological discoveries. CNS Drug Rev. 2002 Spring;8(1):70-89. PMID: 12070527.

 

Nakamura K, Kurasawa M. Anxiolytic effects of aniracetam in three different mouse models of anxiety and the underlying mechanism. Eur J Pharmacol. 2001 May 18;420(1):33-43. PMID: 11412837.

 

Ito I, Tanabe S, Kohda A, et al. Allosteric potentiation of quisqualate receptors by a nootropic drug aniracetam. J Physiol. 1990 May;424:533-43. PMID: 1975272.

" Not dangerous goods.

LKT A5326 Aniracetam 500 mg 312.3 AMPA positive allosteric modulator, D2, 5-HT2A, nAChR agonist. 1-(4-Methoxybenzoyl)-2-pyrrolidinone "Ro-13-5057; Draganon; Sarpul

 

" 72432-10-1 ≥98% 219.24 C12H13NO3 COC1=CC=C(C=C1)C(=O)N2CCCC2=O Ambient Ambient "Soluble in chloroform and ethyl acetate. Slightly soluble in ethanol. Insoluble in water.

" "Wang YF, Li CC, Cai JX. Aniracetam attenuates H2O2-induced deficiency of neuron viability, mitochondria potential and hippocampal long-term potentiation of mice in vitro. Neurosci Bull. 2006 Sep;22(5):274-80. PMID: 17690727.

 

Jin R, Clark S, Weeks AM, et al. Mechanism of positive allosteric modulators acting on AMPA receptors. J Neurosci. 2005 Sep 28;25(39):9027-36. PMID: 16192394.

 

Nakamura K. Aniracetam: its novel therapeutic potential in cerebral dysfunctional disorders based on recent pharmacological discoveries. CNS Drug Rev. 2002 Spring;8(1):70-89. PMID: 12070527.

 

Nakamura K, Kurasawa M. Anxiolytic effects of aniracetam in three different mouse models of anxiety and the underlying mechanism. Eur J Pharmacol. 2001 May 18;420(1):33-43. PMID: 11412837.

 

Ito I, Tanabe S, Kohda A, et al. Allosteric potentiation of quisqualate receptors by a nootropic drug aniracetam. J Physiol. 1990 May;424:533-43. PMID: 1975272.

" Not dangerous goods.

LKT A5326 Aniracetam 1 g 508.3 AMPA positive allosteric modulator, D2, 5-HT2A, nAChR agonist. 1-(4-Methoxybenzoyl)-2-pyrrolidinone "Ro-13-5057; Draganon; Sarpul

 

" 72432-10-1 ≥98% 219.24 C12H13NO3 COC1=CC=C(C=C1)C(=O)N2CCCC2=O Ambient Ambient "Soluble in chloroform and ethyl acetate. Slightly soluble in ethanol. Insoluble in water.

" "Wang YF, Li CC, Cai JX. Aniracetam attenuates H2O2-induced deficiency of neuron viability, mitochondria potential and hippocampal long-term potentiation of mice in vitro. Neurosci Bull. 2006 Sep;22(5):274-80. PMID: 17690727.

 

Jin R, Clark S, Weeks AM, et al. Mechanism of positive allosteric modulators acting on AMPA receptors. J Neurosci. 2005 Sep 28;25(39):9027-36. PMID: 16192394.

 

Nakamura K. Aniracetam: its novel therapeutic potential in cerebral dysfunctional disorders based on recent pharmacological discoveries. CNS Drug Rev. 2002 Spring;8(1):70-89. PMID: 12070527.

 

Nakamura K, Kurasawa M. Anxiolytic effects of aniracetam in three different mouse models of anxiety and the underlying mechanism. Eur J Pharmacol. 2001 May 18;420(1):33-43. PMID: 11412837.

 

Ito I, Tanabe S, Kohda A, et al. Allosteric potentiation of quisqualate receptors by a nootropic drug aniracetam. J Physiol. 1990 May;424:533-43. PMID: 1975272.

" Not dangerous goods.

LKT A5327 Anagrelide 10 mg 122.3 Imidazoquinazoline; PDE3 inhibitor. 6,7-dichloro-5,10-dihydro-3H-imidazo[2,1-b]quinazolin-2-one 68475-42-3 ≥98% 256.09 C10H7Cl2N3O C1C2=C(C=CC(=C2Cl)Cl)NC3=NC(=O)CN31 Ambient Ambient "Ahluwalia M, Donovan H, Singh N, et al. Anagrelide represses GATA-1 and FOG-1 expression without interfering with thrombopoietin receptor signal transduction. J Thromb Haemost. 2010 Oct;8(10):2252-61. PMID: 20586925.

 

McCarty JM, Melone PD, Simanis JP, et al. A preliminary investigation into the action of anagrelide: thrombopoietin-c-Mpl receptor interactions. Exp Hematol. 2006 Jan;34(1):87-96. PMID: 16413395.

 

Wang G, Franklin R, Hong Y, et al. Comparison of the biological activities of anagrelide and its major metabolites in haematopoietic cell cultures. Br J Pharmacol. 2005 Oct;146(3):324-32. PMID: 16041400.

 

Tefferi A, Silverstein MN, Petitt RM, et al. Anagrelide as a new platelet-lowering agent in essential thrombocythemia: mechanism of actin, efficacy, toxicity, current indications. Semin Thromb Hemost. 1997;23(4):379-83. PMID: 9263355.

" Not dangerous goods.

LKT A5327 Anagrelide 25 mg 244.5 Imidazoquinazoline; PDE3 inhibitor. 6,7-dichloro-5,10-dihydro-3H-imidazo[2,1-b]quinazolin-2-one 68475-42-3 ≥98% 256.09 C10H7Cl2N3O C1C2=C(C=CC(=C2Cl)Cl)NC3=NC(=O)CN31 Ambient Ambient "Ahluwalia M, Donovan H, Singh N, et al. Anagrelide represses GATA-1 and FOG-1 expression without interfering with thrombopoietin receptor signal transduction. J Thromb Haemost. 2010 Oct;8(10):2252-61. PMID: 20586925.

 

McCarty JM, Melone PD, Simanis JP, et al. A preliminary investigation into the action of anagrelide: thrombopoietin-c-Mpl receptor interactions. Exp Hematol. 2006 Jan;34(1):87-96. PMID: 16413395.

 

Wang G, Franklin R, Hong Y, et al. Comparison of the biological activities of anagrelide and its major metabolites in haematopoietic cell cultures. Br J Pharmacol. 2005 Oct;146(3):324-32. PMID: 16041400.

 

Tefferi A, Silverstein MN, Petitt RM, et al. Anagrelide as a new platelet-lowering agent in essential thrombocythemia: mechanism of actin, efficacy, toxicity, current indications. Semin Thromb Hemost. 1997;23(4):379-83. PMID: 9263355.

" Not dangerous goods.

LKT A5327 Anagrelide 100 mg 706.7 Imidazoquinazoline; PDE3 inhibitor. 6,7-dichloro-5,10-dihydro-3H-imidazo[2,1-b]quinazolin-2-one 68475-42-3 ≥98% 256.09 C10H7Cl2N3O C1C2=C(C=CC(=C2Cl)Cl)NC3=NC(=O)CN31 Ambient Ambient "Ahluwalia M, Donovan H, Singh N, et al. Anagrelide represses GATA-1 and FOG-1 expression without interfering with thrombopoietin receptor signal transduction. J Thromb Haemost. 2010 Oct;8(10):2252-61. PMID: 20586925.

 

McCarty JM, Melone PD, Simanis JP, et al. A preliminary investigation into the action of anagrelide: thrombopoietin-c-Mpl receptor interactions. Exp Hematol. 2006 Jan;34(1):87-96. PMID: 16413395.

 

Wang G, Franklin R, Hong Y, et al. Comparison of the biological activities of anagrelide and its major metabolites in haematopoietic cell cultures. Br J Pharmacol. 2005 Oct;146(3):324-32. PMID: 16041400.

 

Tefferi A, Silverstein MN, Petitt RM, et al. Anagrelide as a new platelet-lowering agent in essential thrombocythemia: mechanism of actin, efficacy, toxicity, current indications. Semin Thromb Hemost. 1997;23(4):379-83. PMID: 9263355.

" Not dangerous goods.

LKT A5334 Anisodamine 100 mg 38.8 Tropane alkaloid found in Solanaceae plants; α1-adrenergic and mAChR antagonist. "α-(hydroxymethyl)benzeneacetic acid-6-hydroxy- 8-methyl-8-azabicyclo(3.2.1)oct-3-yl ester

" 6-Hydroxy hyoscyamine 55869-99-3 ≥98% 305.37 C17H23NO4 CN1C2CC(CC1C(C2)O)OC(=O)C(CO)C3=CC=CC=C3 Ambient Ambient "Wang W, Chen QF, Li QB, et al. Efficiency of anisodamine for organophosphorus-poisoned patients when atropinization cannot be achieved with high doses of atropine. Environ Toxicol Pharmacol. 2014 Mar;37(2):477-81. PMID: 24561530.

 

Guoshou Z, Chengye Z, Zhihui L, et al. Effects of high dose of anisodamine on the respiratory function of patients with traumatic acute lung injury. Cell Biochem Biophys. 2013 Jun;66(2):365-9. PMID: 23504631.

 

Geng W, Fu XH, Gu XS, et al. Preventive effects of anisodamine against contrast-induced nephropathy in type 2 diabetics with renal insufficiency undergoing coronary angiography or angioplasty. Chin Med J (Engl). 2012 Oct;125(19):3368-72. PMID: 23044290.

 

Zhang ZX, Wang P, Zhang QS, et al. Effects of anisodamine on the expressions of vascular endothelial growth factor and intercellular adhesion molecule 1 in experimental infusion phlebitis. Chin Med J (Engl). 2012 Jan;125(2):300-5. PMID: 22340563.

 

Zhang WW, Song MK, Cui YY, et al. Differential neuropsychopharmacological influences of naturally occurring tropane alkaloids anisodamine versus scopolamine. Neurosci Lett. 2008 Oct 10;443(3):241-5. PMID: 18672024.

 

Varma DR, Yue TL. Adrenoceptor blocking properties of atropine-like agents anisodamine and anisodine on brain and cardiovascular tissues of rats. Br J Pharmacol. 1986 Mar;87(3):587-94. PMID: 2879586.

" Not dangerous goods.

LKT A5334 Anisodamine 500 mg 64.7 Tropane alkaloid found in Solanaceae plants; α1-adrenergic and mAChR antagonist. "α-(hydroxymethyl)benzeneacetic acid-6-hydroxy- 8-methyl-8-azabicyclo(3.2.1)oct-3-yl ester

" 6-Hydroxy hyoscyamine 55869-99-3 ≥98% 305.37 C17H23NO4 CN1C2CC(CC1C(C2)O)OC(=O)C(CO)C3=CC=CC=C3 Ambient Ambient "Wang W, Chen QF, Li QB, et al. Efficiency of anisodamine for organophosphorus-poisoned patients when atropinization cannot be achieved with high doses of atropine. Environ Toxicol Pharmacol. 2014 Mar;37(2):477-81. PMID: 24561530.

 

Guoshou Z, Chengye Z, Zhihui L, et al. Effects of high dose of anisodamine on the respiratory function of patients with traumatic acute lung injury. Cell Biochem Biophys. 2013 Jun;66(2):365-9. PMID: 23504631.

 

Geng W, Fu XH, Gu XS, et al. Preventive effects of anisodamine against contrast-induced nephropathy in type 2 diabetics with renal insufficiency undergoing coronary angiography or angioplasty. Chin Med J (Engl). 2012 Oct;125(19):3368-72. PMID: 23044290.

 

Zhang ZX, Wang P, Zhang QS, et al. Effects of anisodamine on the expressions of vascular endothelial growth factor and intercellular adhesion molecule 1 in experimental infusion phlebitis. Chin Med J (Engl). 2012 Jan;125(2):300-5. PMID: 22340563.

 

Zhang WW, Song MK, Cui YY, et al. Differential neuropsychopharmacological influences of naturally occurring tropane alkaloids anisodamine versus scopolamine. Neurosci Lett. 2008 Oct 10;443(3):241-5. PMID: 18672024.

 

Varma DR, Yue TL. Adrenoceptor blocking properties of atropine-like agents anisodamine and anisodine on brain and cardiovascular tissues of rats. Br J Pharmacol. 1986 Mar;87(3):587-94. PMID: 2879586.

" Not dangerous goods.

LKT A5334 Anisodamine 1 g 110 Tropane alkaloid found in Solanaceae plants; α1-adrenergic and mAChR antagonist. "α-(hydroxymethyl)benzeneacetic acid-6-hydroxy- 8-methyl-8-azabicyclo(3.2.1)oct-3-yl ester

" 6-Hydroxy hyoscyamine 55869-99-3 ≥98% 305.37 C17H23NO4 CN1C2CC(CC1C(C2)O)OC(=O)C(CO)C3=CC=CC=C3 Ambient Ambient "Wang W, Chen QF, Li QB, et al. Efficiency of anisodamine for organophosphorus-poisoned patients when atropinization cannot be achieved with high doses of atropine. Environ Toxicol Pharmacol. 2014 Mar;37(2):477-81. PMID: 24561530.

 

Guoshou Z, Chengye Z, Zhihui L, et al. Effects of high dose of anisodamine on the respiratory function of patients with traumatic acute lung injury. Cell Biochem Biophys. 2013 Jun;66(2):365-9. PMID: 23504631.

 

Geng W, Fu XH, Gu XS, et al. Preventive effects of anisodamine against contrast-induced nephropathy in type 2 diabetics with renal insufficiency undergoing coronary angiography or angioplasty. Chin Med J (Engl). 2012 Oct;125(19):3368-72. PMID: 23044290.

 

Zhang ZX, Wang P, Zhang QS, et al. Effects of anisodamine on the expressions of vascular endothelial growth factor and intercellular adhesion molecule 1 in experimental infusion phlebitis. Chin Med J (Engl). 2012 Jan;125(2):300-5. PMID: 22340563.

 

Zhang WW, Song MK, Cui YY, et al. Differential neuropsychopharmacological influences of naturally occurring tropane alkaloids anisodamine versus scopolamine. Neurosci Lett. 2008 Oct 10;443(3):241-5. PMID: 18672024.

 

Varma DR, Yue TL. Adrenoceptor blocking properties of atropine-like agents anisodamine and anisodine on brain and cardiovascular tissues of rats. Br J Pharmacol. 1986 Mar;87(3):587-94. PMID: 2879586.

" Not dangerous goods.

LKT A5373 Anisomycin 5 mg 48 Peptidyl transferase inhibitor, protein translation inhibitor. 1,4,5-Trideoxy-1,4-imino-5-(p-methoxyphenyl)-D-xylo-pentitol 3-acetate Flagecidin 22862-76-6 ≥98% 265.31 C14H19NO4 CC(=O)OC1C(CNC1CC2=CC=C(C=C2)OC)O Ambient 4°C Moderately soluble in water; sol in lower alcohols, esters or ketones. "Monaghan D, O'Connell E, Cruickshank FL, et al. Inhibition of protein synthesis and JNK activation are not required for cell death induced by anisomycin and anisomycin analogues. Biochem Biophys Res Commun. 2014 Jan 10;443(2):761-7. PMID: 24333448.

 

Yu C, Xing F, Tang Z, et al. Anisomycin suppresses Jurkat T cell growth by the cell cycle-regulating proteins. Pharmacol Rep. 2013;65(2):435-44. PMID: 23744428.

 

You P, Xing F, Huo J, et al. In vitro and in vivo evaluation of anisomycin against Ehrlich ascites carcinoma. Oncol Rep. 2013 Jun;29(6):2227-36. PMID: 23525555.

 

Wang SH, Ostlund SB, Nader K, et al. Consolidation and reconsolidation of incentive learning in the amygdala. J Neurosci. 2005 Jan 26;25(4):830-5. PMID: 15673662.

 

Barrientos RM, O'Reilly RC, Rudy JW. Memory for context is impaired by injecting anisomycin into dorsal hippocampus following context exploration. Behav Brain Res. 2002 Aug 21;134(1-2):299-306. PMID: 12191817.

 

Grollman AP. Inhibitors of protein biosynthesis. II. Mode of action of anisomycin. J Biol Chem. 1967 Jul 10;242(13):3226-33. PMID: 6027796.

" T "UN number: 3462     Class: 6.1     Packing Group: III

Proper shipping name: Toxins, extracted from living sources, solid, n.o.s. (Anisomycin)"

LKT A5373 Anisomycin 25 mg 150 Peptidyl transferase inhibitor, protein translation inhibitor. 1,4,5-Trideoxy-1,4-imino-5-(p-methoxyphenyl)-D-xylo-pentitol 3-acetate Flagecidin 22862-76-6 ≥98% 265.31 C14H19NO4 CC(=O)OC1C(CNC1CC2=CC=C(C=C2)OC)O Ambient 4°C Moderately soluble in water; sol in lower alcohols, esters or ketones. "Monaghan D, O'Connell E, Cruickshank FL, et al. Inhibition of protein synthesis and JNK activation are not required for cell death induced by anisomycin and anisomycin analogues. Biochem Biophys Res Commun. 2014 Jan 10;443(2):761-7. PMID: 24333448.

 

Yu C, Xing F, Tang Z, et al. Anisomycin suppresses Jurkat T cell growth by the cell cycle-regulating proteins. Pharmacol Rep. 2013;65(2):435-44. PMID: 23744428.

 

You P, Xing F, Huo J, et al. In vitro and in vivo evaluation of anisomycin against Ehrlich ascites carcinoma. Oncol Rep. 2013 Jun;29(6):2227-36. PMID: 23525555.

 

Wang SH, Ostlund SB, Nader K, et al. Consolidation and reconsolidation of incentive learning in the amygdala. J Neurosci. 2005 Jan 26;25(4):830-5. PMID: 15673662.

 

Barrientos RM, O'Reilly RC, Rudy JW. Memory for context is impaired by injecting anisomycin into dorsal hippocampus following context exploration. Behav Brain Res. 2002 Aug 21;134(1-2):299-306. PMID: 12191817.

 

Grollman AP. Inhibitors of protein biosynthesis. II. Mode of action of anisomycin. J Biol Chem. 1967 Jul 10;242(13):3226-33. PMID: 6027796.

" T "UN number: 3462     Class: 6.1     Packing Group: III

Proper shipping name: Toxins, extracted from living sources, solid, n.o.s. (Anisomycin)"

LKT A5373 Anisomycin 100 mg 448 Peptidyl transferase inhibitor, protein translation inhibitor. 1,4,5-Trideoxy-1,4-imino-5-(p-methoxyphenyl)-D-xylo-pentitol 3-acetate Flagecidin 22862-76-6 ≥98% 265.31 C14H19NO4 CC(=O)OC1C(CNC1CC2=CC=C(C=C2)OC)O Ambient 4°C Moderately soluble in water; sol in lower alcohols, esters or ketones. "Monaghan D, O'Connell E, Cruickshank FL, et al. Inhibition of protein synthesis and JNK activation are not required for cell death induced by anisomycin and anisomycin analogues. Biochem Biophys Res Commun. 2014 Jan 10;443(2):761-7. PMID: 24333448.

 

Yu C, Xing F, Tang Z, et al. Anisomycin suppresses Jurkat T cell growth by the cell cycle-regulating proteins. Pharmacol Rep. 2013;65(2):435-44. PMID: 23744428.

 

You P, Xing F, Huo J, et al. In vitro and in vivo evaluation of anisomycin against Ehrlich ascites carcinoma. Oncol Rep. 2013 Jun;29(6):2227-36. PMID: 23525555.

 

Wang SH, Ostlund SB, Nader K, et al. Consolidation and reconsolidation of incentive learning in the amygdala. J Neurosci. 2005 Jan 26;25(4):830-5. PMID: 15673662.

 

Barrientos RM, O'Reilly RC, Rudy JW. Memory for context is impaired by injecting anisomycin into dorsal hippocampus following context exploration. Behav Brain Res. 2002 Aug 21;134(1-2):299-306. PMID: 12191817.

 

Grollman AP. Inhibitors of protein biosynthesis. II. Mode of action of anisomycin. J Biol Chem. 1967 Jul 10;242(13):3226-33. PMID: 6027796.

" T "UN number: 3462     Class: 6.1     Packing Group: III

Proper shipping name: Toxins, extracted from living sources, solid, n.o.s. (Anisomycin)"

LKT A5378 Antimycin A 10 mg 97.2 Oxidative phosphorylation inhibitor. 3-Methylbutanoic acid 3-[[3-(formylamino)-2- hydroxy benzoyl]amino]-8-hexyl-2,6-dimethyl-4,9- dioxo-1,5-dioxonan-7-yl ester Isovaleric acid 8-ester with 3-formamido-N-(7-hexyl- 8-hydroxy-4,9-dimethyl-2,6-dioxo-1,5-dioxonan-3,yl)- salicylamide 1397-94-0 >90% 548.63 C28H40N2O9 CCCCCCC1C(C(OC(=O)C(C(OC1=O)C)NC(=O)C2=C(C(=CC=C2)NC=O)O)C)OC(=O)CC(C)C Moisture sensitive. Ambient -20°C Soluble in alcohol, ethanol (50mg/mL),ether, acetone, or chloroform. Slightly soluble in benzene or carbon tetrachloride. Insoluble in water. "Taddeo EP, Laker RC, Breen DS, et al. Opening of the mitochondrial permeability transition pore links mitochondrial dysfunction to insulin resistance in skeletal muscle. Mol Metab. 2013 Nov 26;3(2):124-34. PMID: 24634818.

 

Ma X, Jin M, Cai Y, et al. Mitochondrial electron transport chain complex III is required for antimycin A to inhibit autophagy. Chem Biol. 2011 Nov 23;18(11):1474-81. PMID: 22118681.

 

Quinlan CL, Gerencser AA, Treberg JR, et al. The mechanism of superoxide production by the antimycin-inhibited mitochondrial Q-cycle. J Biol Chem. 2011 Sep 9;286(36):31361-72. PMID: 21708945.

" T "UN number: 3462     Class:  6.1     Packing group:  II

Proper shipping names:  Toxins, extracted from living sources, solid, n.o.s. (Antimycin A)

Reportable quantity (RQ):     Marine pollutant:  No     Poison inhalation hazard:  No"

LKT A5378 Antimycin A 50 mg 364 Oxidative phosphorylation inhibitor. 3-Methylbutanoic acid 3-[[3-(formylamino)-2- hydroxy benzoyl]amino]-8-hexyl-2,6-dimethyl-4,9- dioxo-1,5-dioxonan-7-yl ester Isovaleric acid 8-ester with 3-formamido-N-(7-hexyl- 8-hydroxy-4,9-dimethyl-2,6-dioxo-1,5-dioxonan-3,yl)- salicylamide 1397-94-0 >90% 548.63 C28H40N2O9 CCCCCCC1C(C(OC(=O)C(C(OC1=O)C)NC(=O)C2=C(C(=CC=C2)NC=O)O)C)OC(=O)CC(C)C Moisture sensitive. Ambient -20°C Soluble in alcohol, ethanol (50mg/mL),ether, acetone, or chloroform. Slightly soluble in benzene or carbon tetrachloride. Insoluble in water. "Taddeo EP, Laker RC, Breen DS, et al. Opening of the mitochondrial permeability transition pore links mitochondrial dysfunction to insulin resistance in skeletal muscle. Mol Metab. 2013 Nov 26;3(2):124-34. PMID: 24634818.

 

Ma X, Jin M, Cai Y, et al. Mitochondrial electron transport chain complex III is required for antimycin A to inhibit autophagy. Chem Biol. 2011 Nov 23;18(11):1474-81. PMID: 22118681.

 

Quinlan CL, Gerencser AA, Treberg JR, et al. The mechanism of superoxide production by the antimycin-inhibited mitochondrial Q-cycle. J Biol Chem. 2011 Sep 9;286(36):31361-72. PMID: 21708945.

" T "UN number: 3462     Class:  6.1     Packing group:  II

Proper shipping names:  Toxins, extracted from living sources, solid, n.o.s. (Antimycin A)

Reportable quantity (RQ):     Marine pollutant:  No     Poison inhalation hazard:  No"

LKT A5458 Anorexigenic Peptide 1 mg 23.9 Peptide, alters hormone secretion and feeding behavior. 69275-10-1 ≥95% 323.4 C13H17N5O5 C1CC(=O)NC1C(=O)NC(CC2C=NC=N2)C(=O)NCC(=O)O Ambient -20°C "Blavet N, DeFeudis FV, Clostre F. Lack of effect of the peptide pyro-Glu-His-Gly-OH on food consumption in mice and rats. Gen Pharmacol. 1982;13(2):173-6. PMID: 6807743.

 

Coy D, Jaworek J, Konturek SJ, et al. Effects of anorexigenic peptide on gastric and pancreatic secretion. J Physiol. 1981 May;314:225-35. PMID: 7031225.

"

LKT A5458 Anorexigenic Peptide 2 mg 42 Peptide, alters hormone secretion and feeding behavior. 69275-10-1 ≥95% 323.4 C13H17N5O5 C1CC(=O)NC1C(=O)NC(CC2C=NC=N2)C(=O)NCC(=O)O Ambient -20°C "Blavet N, DeFeudis FV, Clostre F. Lack of effect of the peptide pyro-Glu-His-Gly-OH on food consumption in mice and rats. Gen Pharmacol. 1982;13(2):173-6. PMID: 6807743.

 

Coy D, Jaworek J, Konturek SJ, et al. Effects of anorexigenic peptide on gastric and pancreatic secretion. J Physiol. 1981 May;314:225-35. PMID: 7031225.

"

LKT A5458 Anorexigenic Peptide 5 mg 72.1 Peptide, alters hormone secretion and feeding behavior. 69275-10-1 ≥95% 323.4 C13H17N5O5 C1CC(=O)NC1C(=O)NC(CC2C=NC=N2)C(=O)NCC(=O)O Ambient -20°C "Blavet N, DeFeudis FV, Clostre F. Lack of effect of the peptide pyro-Glu-His-Gly-OH on food consumption in mice and rats. Gen Pharmacol. 1982;13(2):173-6. PMID: 6807743.

 

Coy D, Jaworek J, Konturek SJ, et al. Effects of anorexigenic peptide on gastric and pancreatic secretion. J Physiol. 1981 May;314:225-35. PMID: 7031225.

"

LKT A5460 A-type Natriuretic Peptide (1-11), rat 1 mg 96 Endogenous cardiomodulatory peptide; NPR-A agonist. Atrial natriuretic peptide; ANP ≥95% 1224.4 C49H83N20O15S1 Ambient -20°C "Vesely DL. New anticancer agents: hormones made within the heart. Anticancer Res. 2012 Jul;32(7):2515-21. PMID: 22753708.

 

Woodard GE, Rosado JA. Natriuretic peptides in vascular physiology and pathology. Int Rev Cell Mol Biol. 2008;268:59-93. PMID: 18703404.

"

LKT A5460 A-type Natriuretic Peptide (1-11), rat 2 mg 489.1 Endogenous cardiomodulatory peptide; NPR-A agonist. Atrial natriuretic peptide; ANP ≥95% 1224.4 C49H83N20O15S1 Ambient -20°C "Vesely DL. New anticancer agents: hormones made within the heart. Anticancer Res. 2012 Jul;32(7):2515-21. PMID: 22753708.

 

Woodard GE, Rosado JA. Natriuretic peptides in vascular physiology and pathology. Int Rev Cell Mol Biol. 2008;268:59-93. PMID: 18703404.

"

LKT A5460 A-type Natriuretic Peptide (1-11), rat 5 mg 864 Endogenous cardiomodulatory peptide; NPR-A agonist. Atrial natriuretic peptide; ANP ≥95% 1224.4 C49H83N20O15S1 Ambient -20°C "Vesely DL. New anticancer agents: hormones made within the heart. Anticancer Res. 2012 Jul;32(7):2515-21. PMID: 22753708.

 

Woodard GE, Rosado JA. Natriuretic peptides in vascular physiology and pathology. Int Rev Cell Mol Biol. 2008;268:59-93. PMID: 18703404.

"

LKT A5461 A-type Natriuretic Peptide (1-30), frog 0.5 mg 23.9 Endogenous cardiomodulatory peptide; NPR-A agonist. Atrial natriuretic peptide; ANP ≥95% 3260.73 C131H215N49O41S4 Ambient -20°C "Vesely DL. New anticancer agents: hormones made within the heart. Anticancer Res. 2012 Jul;32(7):2515-21. PMID: 22753708.

 

Woodard GE, Rosado JA. Natriuretic peptides in vascular physiology and pathology. Int Rev Cell Mol Biol. 2008;268:59-93. PMID: 18703404.

"

LKT A5461 A-type Natriuretic Peptide (1-30), frog 1 mg 42 Endogenous cardiomodulatory peptide; NPR-A agonist. Atrial natriuretic peptide; ANP ≥95% 3260.73 C131H215N49O41S4 Ambient -20°C "Vesely DL. New anticancer agents: hormones made within the heart. Anticancer Res. 2012 Jul;32(7):2515-21. PMID: 22753708.

 

Woodard GE, Rosado JA. Natriuretic peptides in vascular physiology and pathology. Int Rev Cell Mol Biol. 2008;268:59-93. PMID: 18703404.

"

LKT A5461 A-type Natriuretic Peptide (1-30), frog 2.5 mg 72.1 Endogenous cardiomodulatory peptide; NPR-A agonist. Atrial natriuretic peptide; ANP ≥95% 3260.73 C131H215N49O41S4 Ambient -20°C "Vesely DL. New anticancer agents: hormones made within the heart. Anticancer Res. 2012 Jul;32(7):2515-21. PMID: 22753708.

 

Woodard GE, Rosado JA. Natriuretic peptides in vascular physiology and pathology. Int Rev Cell Mol Biol. 2008;268:59-93. PMID: 18703404.

"

LKT A5478 Antipain Dihydrochloride 1 mg 52.3 Oligopeptide found in Actinomycetes; protease inhibitor. [(S)-1-Carboxy-2-phenylethyl]carbamoyl-L-arginyl-L- valyl-argininal 37682-72-7 ≥98% 677.62 C27H44N10O6 2HCl CC(C)C(C(=O)NC(CCCN=C(N)N)C=O)NC(=O)C(CCCN=C(N)N)NC(=O)NC(CC1=CC=CC=C1)C(=O)O Ambient -20°C Soluble in water (10 mg/ml), methanol, ethanol. "Anisuzzaman, Islam MK, Alim MA, et al. Longistatin is an unconventional serine protease and induces protective immunity against tick infestation. Mol Biochem Parasitol. 2012 Mar-Apr;182(1-2):45-53. PMID: 22206819.

 

He SH, Chen P, Chen HQ. Modulation of enzymatic activity of human mast cell tryptase and chymase by protease inhibitors. Acta Pharmacol Sin. 2003 Sep;24(9):923-9. PMID: 12956943.

 

Suda H, Aoyagi T, Hamada M, et al. Antipain, a new protease inhibitor isolated from actinomycetes. J Antibiot (Tokyo). 1972 Apr;25(4):263-6. PMID: 4559651.

" Not dangerous goods.

LKT A5478 Antipain Dihydrochloride 5 mg 146.3 Oligopeptide found in Actinomycetes; protease inhibitor. [(S)-1-Carboxy-2-phenylethyl]carbamoyl-L-arginyl-L- valyl-argininal 37682-72-7 ≥98% 677.62 C27H44N10O6 2HCl CC(C)C(C(=O)NC(CCCN=C(N)N)C=O)NC(=O)C(CCCN=C(N)N)NC(=O)NC(CC1=CC=CC=C1)C(=O)O Ambient -20°C Soluble in water (10 mg/ml), methanol, ethanol. "Anisuzzaman, Islam MK, Alim MA, et al. Longistatin is an unconventional serine protease and induces protective immunity against tick infestation. Mol Biochem Parasitol. 2012 Mar-Apr;182(1-2):45-53. PMID: 22206819.

 

He SH, Chen P, Chen HQ. Modulation of enzymatic activity of human mast cell tryptase and chymase by protease inhibitors. Acta Pharmacol Sin. 2003 Sep;24(9):923-9. PMID: 12956943.

 

Suda H, Aoyagi T, Hamada M, et al. Antipain, a new protease inhibitor isolated from actinomycetes. J Antibiot (Tokyo). 1972 Apr;25(4):263-6. PMID: 4559651.

" Not dangerous goods.

LKT A5478 Antipain Dihydrochloride 25 mg 518.8 Oligopeptide found in Actinomycetes; protease inhibitor. [(S)-1-Carboxy-2-phenylethyl]carbamoyl-L-arginyl-L- valyl-argininal 37682-72-7 ≥98% 677.62 C27H44N10O6 2HCl CC(C)C(C(=O)NC(CCCN=C(N)N)C=O)NC(=O)C(CCCN=C(N)N)NC(=O)NC(CC1=CC=CC=C1)C(=O)O Ambient -20°C Soluble in water (10 mg/ml), methanol, ethanol. "Anisuzzaman, Islam MK, Alim MA, et al. Longistatin is an unconventional serine protease and induces protective immunity against tick infestation. Mol Biochem Parasitol. 2012 Mar-Apr;182(1-2):45-53. PMID: 22206819.

 

He SH, Chen P, Chen HQ. Modulation of enzymatic activity of human mast cell tryptase and chymase by protease inhibitors. Acta Pharmacol Sin. 2003 Sep;24(9):923-9. PMID: 12956943.

 

Suda H, Aoyagi T, Hamada M, et al. Antipain, a new protease inhibitor isolated from actinomycetes. J Antibiot (Tokyo). 1972 Apr;25(4):263-6. PMID: 4559651.

" Not dangerous goods.

LKT A5479 Antiestrogen Peptide 0.5 mg 132 Peptide, antiestrogen. ≥95% 1470.64 C64H104N13O22SP Ambient -20°C

LKT A5479 Antiestrogen Peptide 1 mg 225 Peptide, antiestrogen. ≥95% 1470.64 C64H104N13O22SP Ambient -20°C

LKT A5479 Antiestrogen Peptide 2.5 mg 396.1 Peptide, antiestrogen. ≥95% 1470.64 C64H104N13O22SP Ambient -20°C

LKT A6002 Apamin 0.5 mg 156 Peptide, bee venom toxin; SK2/3/4 K+ channel blocker. 24345-16-2 ≥95% 2027.37 C79H131N31O24S4 CC1C(=O)NC(C(=O)NC(C(=O)NC(CSSCC2C(=O)NC(C(=O)NC(C(=O)N3CCCC3C(=O)NC(C(=O)NC(C(=O)NC(C(=O)NC(C(=O)NC(CSSCC(C(=O)NC(C(=O)N2)CC(=O)N)N)C(=O)N1)CC(C)C)C)C(C)O)CCC(=O)O)C)CCCCN)C(=O)NC(CCC(=O)N)C(=O)NC(CCC(=O)N)C(=O)NC(CC4=CN=CN4)C(=O)N)CCCNC(=N)N)CCCNC(=N)N Ambient -20°C "Dalaklioglu S, Ozbey G. Role of different types of potassium channels in the relaxation of corpus cavernosum induced by resveratrol. Pharmacogn Mag. 2014 Jan;10(37):47-52. PMID: 24696545.

 

Kallarackal AJ, Simard JM, Bailey AM. The effect of apamin, a small conductance calcium activated potassium (SK) channel blocker, on a mouse model of neurofibromatosis 1. Behav Brain Res. 2013 Jan 15;237:71-5. PMID: 22983217.

 

Lamy C, Goodchild SJ, Weatherall KL, et al. Allosteric block of KCa2 channels by apamin. J Biol Chem. 2010 Aug 27;285(35):27067-77. PMID: 20562108.

" Not dangerous goods.

LKT A6002 Apamin 1 mg 264.1 Peptide, bee venom toxin; SK2/3/4 K+ channel blocker. 24345-16-2 ≥95% 2027.37 C79H131N31O24S4 CC1C(=O)NC(C(=O)NC(C(=O)NC(CSSCC2C(=O)NC(C(=O)NC(C(=O)N3CCCC3C(=O)NC(C(=O)NC(C(=O)NC(C(=O)NC(C(=O)NC(CSSCC(C(=O)NC(C(=O)N2)CC(=O)N)N)C(=O)N1)CC(C)C)C)C(C)O)CCC(=O)O)C)CCCCN)C(=O)NC(CCC(=O)N)C(=O)NC(CCC(=O)N)C(=O)NC(CC4=CN=CN4)C(=O)N)CCCNC(=N)N)CCCNC(=N)N Ambient -20°C "Dalaklioglu S, Ozbey G. Role of different types of potassium channels in the relaxation of corpus cavernosum induced by resveratrol. Pharmacogn Mag. 2014 Jan;10(37):47-52. PMID: 24696545.

 

Kallarackal AJ, Simard JM, Bailey AM. The effect of apamin, a small conductance calcium activated potassium (SK) channel blocker, on a mouse model of neurofibromatosis 1. Behav Brain Res. 2013 Jan 15;237:71-5. PMID: 22983217.

 

Lamy C, Goodchild SJ, Weatherall KL, et al. Allosteric block of KCa2 channels by apamin. J Biol Chem. 2010 Aug 27;285(35):27067-77. PMID: 20562108.

" Not dangerous goods.

LKT A6002 Apamin 2.5 mg 468.2 Peptide, bee venom toxin; SK2/3/4 K+ channel blocker. 24345-16-2 ≥95% 2027.37 C79H131N31O24S4 CC1C(=O)NC(C(=O)NC(C(=O)NC(CSSCC2C(=O)NC(C(=O)NC(C(=O)N3CCCC3C(=O)NC(C(=O)NC(C(=O)NC(C(=O)NC(C(=O)NC(CSSCC(C(=O)NC(C(=O)N2)CC(=O)N)N)C(=O)N1)CC(C)C)C)C(C)O)CCC(=O)O)C)CCCCN)C(=O)NC(CCC(=O)N)C(=O)NC(CCC(=O)N)C(=O)NC(CC4=CN=CN4)C(=O)N)CCCNC(=N)N)CCCNC(=N)N Ambient -20°C "Dalaklioglu S, Ozbey G. Role of different types of potassium channels in the relaxation of corpus cavernosum induced by resveratrol. Pharmacogn Mag. 2014 Jan;10(37):47-52. PMID: 24696545.

 

Kallarackal AJ, Simard JM, Bailey AM. The effect of apamin, a small conductance calcium activated potassium (SK) channel blocker, on a mouse model of neurofibromatosis 1. Behav Brain Res. 2013 Jan 15;237:71-5. PMID: 22983217.

 

Lamy C, Goodchild SJ, Weatherall KL, et al. Allosteric block of KCa2 channels by apamin. J Biol Chem. 2010 Aug 27;285(35):27067-77. PMID: 20562108.

" Not dangerous goods.

LKT A6017 Apelin-13, human/cow 0.5 mg 96 Endogenous peptide, involved in vascular contraction, water homeostasis, feeding behavior; APJ agonist. ≥95% 1550.86 C69H111N23O16S Ambient -20°C "Yang Y, Zhang X, Cui H, et al. Apelin-13 protects the brain against ischemia/reperfusion injury through activating PI3K/Akt and ERK1/2 signaling pathways. Neurosci Lett. 2014 Mar 29;568C:44-49. [Epub ahead of print]. PMID: 24686182.

 

Bo B, Lulu L, Ning Z, et al. Heterodimerization of human apelin and bradykinin 1 receptors: Novel signal transduction characteristics. Cell Signal. 2014 Mar 29. pii: S0898-6568(14)00124-7. [Epub ahead of print]. PMID: 24686079.

 

Yang X, Zhu W, Zhang P, et al. Apelin-13 stimulates angiogenesis by promoting cross talk between AMP-activated protein kinase and Akt signaling in myocardial microvascular endothelial cells. Mol Med Rep. 2014 May;9(5):1590-6. PMID: 24573187.

 

Xu S, Han P, Huang M, et al. In vivo, ex vivo, and in vitro studies on apelin's effect on myocardial glucose uptake. Peptides. 2012 Oct;37(2):320-6. PMID: 22906703.

"

LKT A6017 Apelin-13, human/cow 1 mg 162 Endogenous peptide, involved in vascular contraction, water homeostasis, feeding behavior; APJ agonist. ≥95% 1550.86 C69H111N23O16S Ambient -20°C "Yang Y, Zhang X, Cui H, et al. Apelin-13 protects the brain against ischemia/reperfusion injury through activating PI3K/Akt and ERK1/2 signaling pathways. Neurosci Lett. 2014 Mar 29;568C:44-49. [Epub ahead of print]. PMID: 24686182.

 

Bo B, Lulu L, Ning Z, et al. Heterodimerization of human apelin and bradykinin 1 receptors: Novel signal transduction characteristics. Cell Signal. 2014 Mar 29. pii: S0898-6568(14)00124-7. [Epub ahead of print]. PMID: 24686079.

 

Yang X, Zhu W, Zhang P, et al. Apelin-13 stimulates angiogenesis by promoting cross talk between AMP-activated protein kinase and Akt signaling in myocardial microvascular endothelial cells. Mol Med Rep. 2014 May;9(5):1590-6. PMID: 24573187.

 

Xu S, Han P, Huang M, et al. In vivo, ex vivo, and in vitro studies on apelin's effect on myocardial glucose uptake. Peptides. 2012 Oct;37(2):320-6. PMID: 22906703.

"

LKT A6017 Apelin-13, human/cow 2.5 mg 287.9 Endogenous peptide, involved in vascular contraction, water homeostasis, feeding behavior; APJ agonist. ≥95% 1550.86 C69H111N23O16S Ambient -20°C "Yang Y, Zhang X, Cui H, et al. Apelin-13 protects the brain against ischemia/reperfusion injury through activating PI3K/Akt and ERK1/2 signaling pathways. Neurosci Lett. 2014 Mar 29;568C:44-49. [Epub ahead of print]. PMID: 24686182.

 

Bo B, Lulu L, Ning Z, et al. Heterodimerization of human apelin and bradykinin 1 receptors: Novel signal transduction characteristics. Cell Signal. 2014 Mar 29. pii: S0898-6568(14)00124-7. [Epub ahead of print]. PMID: 24686079.

 

Yang X, Zhu W, Zhang P, et al. Apelin-13 stimulates angiogenesis by promoting cross talk between AMP-activated protein kinase and Akt signaling in myocardial microvascular endothelial cells. Mol Med Rep. 2014 May;9(5):1590-6. PMID: 24573187.

 

Xu S, Han P, Huang M, et al. In vivo, ex vivo, and in vitro studies on apelin's effect on myocardial glucose uptake. Peptides. 2012 Oct;37(2):320-6. PMID: 22906703.

"

LKT A6132 Apicidin 1 mg 84.3 Cyclic tetrapeptide; HDAC inhibitor. 183506-66-3 ≥98% 623.78 C34H49N5O6 CCC(C)C1C(=O)N2CCCCC2C(=O)NC(C(=O)NC(C(=O)N1)CC3=CN(C4=CC=CC=C43)OC)CCCCCC(=O)OC Ambient 4°C "Ethanol, DMSO, Dichloromethane.

Slightly soluble in water, methanol" "Ahn MY, Ahn SG, Yoon JH. Apicidin, a histone deaceylase inhibitor, induces both apoptosis and autophagy in human oral squamous carcinoma cells. Oral Oncol. 2011 Nov;47(11):1032-8. PMID: 21856210.

 

Brazelle W, Kreahling JM, Gemmer J, et al. Histone deacetylase inhibitors downregulate checkpoint kinase 1 expression to induce cell death in non-small cell lung cancer cells. PLoS One. 2010 Dec 14;5(12):e14335. PMID: 21179472.

 

Kankaanranta H, Janka-Junttila M, Ilmarinen-Salo P, et al. Histone deacetylase inhibitors induce apoptosis in human eosinophils and neutrophils. J Inflamm (Lond). 2010 Feb 4;7:9. PMID: 20181093.

 

Cheong JW, Chong SY, Kim JY, et al. Induction of apoptosis by apicidin, a histone deacetylase inhibitor, via the activation of mitochondria-dependent caspase cascades in human Bcr-Abl-positive leukemia cells. Clin Cancer Res. 2003 Oct 15;9(13):5018-27. PMID: 14581377.

" T+ "UN number: 2811    Class:  6.1     Packing group:  II

Proper shipping name:  Toxic solid, organic, n.o.s. (Apicidin)

Marine pollutant:  No     Poison Inhalation Hazard:  No."

LKT A6132 Apicidin 5 mg 375.1 Cyclic tetrapeptide; HDAC inhibitor. 183506-66-3 ≥98% 623.78 C34H49N5O6 CCC(C)C1C(=O)N2CCCCC2C(=O)NC(C(=O)NC(C(=O)N1)CC3=CN(C4=CC=CC=C43)OC)CCCCCC(=O)OC Ambient 4°C "Ethanol, DMSO, Dichloromethane.

Slightly soluble in water, methanol" "Ahn MY, Ahn SG, Yoon JH. Apicidin, a histone deaceylase inhibitor, induces both apoptosis and autophagy in human oral squamous carcinoma cells. Oral Oncol. 2011 Nov;47(11):1032-8. PMID: 21856210.

 

Brazelle W, Kreahling JM, Gemmer J, et al. Histone deacetylase inhibitors downregulate checkpoint kinase 1 expression to induce cell death in non-small cell lung cancer cells. PLoS One. 2010 Dec 14;5(12):e14335. PMID: 21179472.

 

Kankaanranta H, Janka-Junttila M, Ilmarinen-Salo P, et al. Histone deacetylase inhibitors induce apoptosis in human eosinophils and neutrophils. J Inflamm (Lond). 2010 Feb 4;7:9. PMID: 20181093.

 

Cheong JW, Chong SY, Kim JY, et al. Induction of apoptosis by apicidin, a histone deacetylase inhibitor, via the activation of mitochondria-dependent caspase cascades in human Bcr-Abl-positive leukemia cells. Clin Cancer Res. 2003 Oct 15;9(13):5018-27. PMID: 14581377.

" T+ "UN number: 2811    Class:  6.1     Packing group:  II

Proper shipping name:  Toxic solid, organic, n.o.s. (Apicidin)

Marine pollutant:  No     Poison Inhalation Hazard:  No."

LKT A6229 Aphidicolin 1 mg 149.9 Diterpene antibiotic produced by Cephalosporum; eukaryotic and viral DNA polymerase inhibitor. (3α,4α,5α,17α)-3,17-Dihydroxy-4-methyl-9,15-cyclo-C,18-dinor-14,15-secoandrostane-4,17-dimethanol ICI-69653; NSC-234714 38966-21-1 ≥98% 338.48 C20H34O4 CC12CCC(C(C1CCC3C24CCC(C(C3)C4)(CO)O)(C)CO)O Ambient -20°C Soluble in DMSO, ethanol. "Willis J, DeStephanis D, Patel Y, et al. Study of the DNA damage checkpoint using Xenopus egg extracts. J Vis Exp. 2012 Nov 5;(69):e4449. PMID: 23149695.

 

Zhao YM, Li JY, Lan JP, et al. Cell cycle dependent telomere regulation by telomerase in human bone marrow mesenchymal stem cells. Biochem Biophys Res Commun. 2008 May 16;369(4):1114-9. PMID: 8339310.

 

DeFilippes FM. Effect of aphidicolin on vaccinia virus: isolation of an aphidicolin-resistant mutant. J Virol. 1984 Nov;52(2):474-82. PMID: 6436508.

" Not dangerous goods.

LKT A6229 Aphidicolin 5 mg 562.5 Diterpene antibiotic produced by Cephalosporum; eukaryotic and viral DNA polymerase inhibitor. (3α,4α,5α,17α)-3,17-Dihydroxy-4-methyl-9,15-cyclo-C,18-dinor-14,15-secoandrostane-4,17-dimethanol ICI-69653; NSC-234714 38966-21-1 ≥98% 338.48 C20H34O4 CC12CCC(C(C1CCC3C24CCC(C(C3)C4)(CO)O)(C)CO)O Ambient -20°C Soluble in DMSO, ethanol. "Willis J, DeStephanis D, Patel Y, et al. Study of the DNA damage checkpoint using Xenopus egg extracts. J Vis Exp. 2012 Nov 5;(69):e4449. PMID: 23149695.

 

Zhao YM, Li JY, Lan JP, et al. Cell cycle dependent telomere regulation by telomerase in human bone marrow mesenchymal stem cells. Biochem Biophys Res Commun. 2008 May 16;369(4):1114-9. PMID: 8339310.

 

DeFilippes FM. Effect of aphidicolin on vaccinia virus: isolation of an aphidicolin-resistant mutant. J Virol. 1984 Nov;52(2):474-82. PMID: 6436508.

" Not dangerous goods.

LKT A6229 Aphidicolin 10 mg 984.5 Diterpene antibiotic produced by Cephalosporum; eukaryotic and viral DNA polymerase inhibitor. (3α,4α,5α,17α)-3,17-Dihydroxy-4-methyl-9,15-cyclo-C,18-dinor-14,15-secoandrostane-4,17-dimethanol ICI-69653; NSC-234714 38966-21-1 ≥98% 338.48 C20H34O4 CC12CCC(C(C1CCC3C24CCC(C(C3)C4)(CO)O)(C)CO)O Ambient -20°C Soluble in DMSO, ethanol. "Willis J, DeStephanis D, Patel Y, et al. Study of the DNA damage checkpoint using Xenopus egg extracts. J Vis Exp. 2012 Nov 5;(69):e4449. PMID: 23149695.

 

Zhao YM, Li JY, Lan JP, et al. Cell cycle dependent telomere regulation by telomerase in human bone marrow mesenchymal stem cells. Biochem Biophys Res Commun. 2008 May 16;369(4):1114-9. PMID: 8339310.

 

DeFilippes FM. Effect of aphidicolin on vaccinia virus: isolation of an aphidicolin-resistant mutant. J Virol. 1984 Nov;52(2):474-82. PMID: 6436508.

" Not dangerous goods.

LKT A6234 Apigenin 5 mg 35.3 Flavonoid found in various plant sources; GABA-A positive modulator, potential microtubule depolymerization inducer. "5,7-dihydroxy-2-(4-hydroxyphenyl)-(9CI)-4H- 1-Benzopyran-4-one 

" Apigenine; Apigenol; Chamomile; Spigenin; Versulin 520-36-5 ≥98% 270.24 C15H10O5 C1=CC(=CC=C1C2=CC(=O)C3=C(C=C(C=C3O2)O)O)O Ambient Ambient Moderately soluble in hot alcohol. Soluble in dilute KOH. "Chen J, Chen J, Li Z, et al. The apoptotic effect of apigenin on human gastric carcinoma cells through mitochondrial signal pathway. Tumour Biol. 2014 May 8. [Epub ahead of print]. PMID: 24805829.

 

Zhang F, Li F, Chen G. Neuroprotective effect of apigenin in rats after contusive spinal cord injury. Neurol Sci. 2014 Apr;35(4):583-8. PMID: 24166720.

 

Je HD, Kim HD, La HO. The Inhibitory Effect of Apigenin on the Agonist-Induced Regulation of Vascular Contractility via Calcium Desensitization-Related Pathways. Biomol Ther (Seoul). 2014 Feb;22(2):100-5. PMID: 24753814.

 

Zhao L, Wang JL, Liu R, et al. Neuroprotective, anti-amyloidogenic and neurotrophic effects of apigenin in an Alzheimer's disease mouse model. Molecules. 2013 Aug 19;18(8):9949-65. PMID: 23966081.

 

Choudhury D, Ganguli A, Dastidar DG, et al. Apigenin shows synergistic anticancer activity with curcumin by binding at different sites of tubulin. Biochimie. 2013 Jun;95(6):1297-309. PMID: 23485682.

" Xi Not dangerous goods.

LKT A6234 Apigenin 25 mg 65.3 Flavonoid found in various plant sources; GABA-A positive modulator, potential microtubule depolymerization inducer. "5,7-dihydroxy-2-(4-hydroxyphenyl)-(9CI)-4H- 1-Benzopyran-4-one 

" Apigenine; Apigenol; Chamomile; Spigenin; Versulin 520-36-5 ≥98% 270.24 C15H10O5 C1=CC(=CC=C1C2=CC(=O)C3=C(C=C(C=C3O2)O)O)O Ambient Ambient Moderately soluble in hot alcohol. Soluble in dilute KOH. "Chen J, Chen J, Li Z, et al. The apoptotic effect of apigenin on human gastric carcinoma cells through mitochondrial signal pathway. Tumour Biol. 2014 May 8. [Epub ahead of print]. PMID: 24805829.

 

Zhang F, Li F, Chen G. Neuroprotective effect of apigenin in rats after contusive spinal cord injury. Neurol Sci. 2014 Apr;35(4):583-8. PMID: 24166720.

 

Je HD, Kim HD, La HO. The Inhibitory Effect of Apigenin on the Agonist-Induced Regulation of Vascular Contractility via Calcium Desensitization-Related Pathways. Biomol Ther (Seoul). 2014 Feb;22(2):100-5. PMID: 24753814.

 

Zhao L, Wang JL, Liu R, et al. Neuroprotective, anti-amyloidogenic and neurotrophic effects of apigenin in an Alzheimer's disease mouse model. Molecules. 2013 Aug 19;18(8):9949-65. PMID: 23966081.

 

Choudhury D, Ganguli A, Dastidar DG, et al. Apigenin shows synergistic anticancer activity with curcumin by binding at different sites of tubulin. Biochimie. 2013 Jun;95(6):1297-309. PMID: 23485682.

" Xi Not dangerous goods.

LKT A6234 Apigenin 100 mg 163.2 Flavonoid found in various plant sources; GABA-A positive modulator, potential microtubule depolymerization inducer. "5,7-dihydroxy-2-(4-hydroxyphenyl)-(9CI)-4H- 1-Benzopyran-4-one 

" Apigenine; Apigenol; Chamomile; Spigenin; Versulin 520-36-5 ≥98% 270.24 C15H10O5 C1=CC(=CC=C1C2=CC(=O)C3=C(C=C(C=C3O2)O)O)O Ambient Ambient Moderately soluble in hot alcohol. Soluble in dilute KOH. "Chen J, Chen J, Li Z, et al. The apoptotic effect of apigenin on human gastric carcinoma cells through mitochondrial signal pathway. Tumour Biol. 2014 May 8. [Epub ahead of print]. PMID: 24805829.

 

Zhang F, Li F, Chen G. Neuroprotective effect of apigenin in rats after contusive spinal cord injury. Neurol Sci. 2014 Apr;35(4):583-8. PMID: 24166720.

 

Je HD, Kim HD, La HO. The Inhibitory Effect of Apigenin on the Agonist-Induced Regulation of Vascular Contractility via Calcium Desensitization-Related Pathways. Biomol Ther (Seoul). 2014 Feb;22(2):100-5. PMID: 24753814.

 

Zhao L, Wang JL, Liu R, et al. Neuroprotective, anti-amyloidogenic and neurotrophic effects of apigenin in an Alzheimer's disease mouse model. Molecules. 2013 Aug 19;18(8):9949-65. PMID: 23966081.

 

Choudhury D, Ganguli A, Dastidar DG, et al. Apigenin shows synergistic anticancer activity with curcumin by binding at different sites of tubulin. Biochimie. 2013 Jun;95(6):1297-309. PMID: 23485682.

" Xi Not dangerous goods.

LKT A6264 Apramycin Sulfate 1 g 58.2 Aminoglycoside; protein translation inhibitor. O-4-Amino-4-deoxy-α-D-glucopyranosyl-(1->8)-O- (8R)-2-amino-2,3,7-trideoxy-7-(methylamino)-D- glycero-α-D-allo-octodialdo-1,5:8,4-dipyranosyl- (1->4)-2-deoxy-D-streptamine Nebramycin factor 2; EL-857; Apralan 65710-07-8 ≥98% 637.66 C21H41N5O11 H2O4S    CNC1C(C2C(CC(C(O2)OC3C(CC(C(C3O)O)N)N)N)OC1OC4C(C(C(C(O4)CO)N)O)O)O.OS(=O)(=O)O Ambient 4°C "Witek MA, Conn GL. Expansion of the aminoglycoside-resistance 16S rRNA (m1A1408) methyltransferase family: Expression and functional characterization of four hypothetical enzymes of diverse bacterial origin. Biochim Biophys Acta. 2014 Jun 22. [Epub ahead of print]. PMID: 24963996.

 

Choi MJ, Lim SK, Nam HM, et al. Apramycin and gentamicin resistances in indicator and clinical Escherichia coli isolates from farm animals in Korea. Foodborne Pathog Dis. 2011 Jan;8(1):119-23. PMID: 21214385.

" Not dangerous goods.

LKT A6264 Apramycin Sulfate 5 g 213.6 Aminoglycoside; protein translation inhibitor. O-4-Amino-4-deoxy-α-D-glucopyranosyl-(1->8)-O- (8R)-2-amino-2,3,7-trideoxy-7-(methylamino)-D- glycero-α-D-allo-octodialdo-1,5:8,4-dipyranosyl- (1->4)-2-deoxy-D-streptamine Nebramycin factor 2; EL-857; Apralan 65710-07-8 ≥98% 637.66 C21H41N5O11 H2O4S    CNC1C(C2C(CC(C(O2)OC3C(CC(C(C3O)O)N)N)N)OC1OC4C(C(C(C(O4)CO)N)O)O)O.OS(=O)(=O)O Ambient 4°C "Witek MA, Conn GL. Expansion of the aminoglycoside-resistance 16S rRNA (m1A1408) methyltransferase family: Expression and functional characterization of four hypothetical enzymes of diverse bacterial origin. Biochim Biophys Acta. 2014 Jun 22. [Epub ahead of print]. PMID: 24963996.

 

Choi MJ, Lim SK, Nam HM, et al. Apramycin and gentamicin resistances in indicator and clinical Escherichia coli isolates from farm animals in Korea. Foodborne Pathog Dis. 2011 Jan;8(1):119-23. PMID: 21214385.

" Not dangerous goods.

LKT A6268 Aprotinin 10 mg 101.9 Polypeptide; serine protease inhibitor. Pancreatic trypsin inhibitor; Antagosan; Fosten; Iniprol; Repulson; Trazinin; Zymofren 9087-70-1 ≥98% 6511.44 C284H432N84O79S7 CCC(C)C1C(=O)NC(C(=O)NC(C(=O)NC(C(=O)NC(C(=O)NC(C(=O)NC(C(=O)NC(C(=O)NC(C(=O)NC(C(=O)NCC(=O)NC(C(=O)NC2CSSCC3C(=O)NC(C(=O)NC(C(=O)NC(C(=O)NC(CSSCC(C(=O)NC(C(=O)NC(C(=O)N4CCCC4C(=O)N5CCCC5C(=O)NC(C(=O)NC(C(=O)NCC(=O)N6CCCC6C(=O)NC(CSSCC(C(=O)NC(C(=O)NC(C(=O)NC(C(=O)NC(C(=O)NC(C(=O)NC(C(=O)NC(C(=O)NC(C(=O)NC(C(=O)NC(C(=O)NC(C(=O)NC(C(=O)N3)CC(=O)O)CCC(=O)O)C)CO)CCCCN)CC7=CC=CC=C7)CC(=O)N)CC(=O)N)CCCNC(=N)N)CCCCN)C)CCCNC(=N)N)NC(=O)CNC(=O)CNC(=O)C(NC(=O)C(NC(=O)C(NC(=O)C(NC(=O)C(NC2=O)CCC(=O)N)C(C)O)CC8=CC=CC=C8)C(C)C)CC9=CC=C(C=C9)O)C(=O)NC(C(=O)NC(C(=O)NC(C(=O)N1)CCCNC(=N)N)C)CCCCN)C(C)O)CC1=CC=C(C=C1)O)CCC(=O)O)CC(C)C)NC(=O)C(CC1=CC=CC=C1)NC(=O)C(CC(=O)O)NC(=O)C1CCCN1C(=O)C(CCCNC(=N)N)N)C(=O)NCC(=O)NCC(=O)NC(C)C(=O)O)C(C)O)CCCNC(=N)N)CCSC)CC(C)C)C)CCCCN)C)CC(=O)N)CC1=CC=C(C=C1)O)CC1=CC=CC=C1)CC1=CC=C(C=C1)O)CCCNC(=N)N)C(C)CC Protect from moisture. Ambient 4°C Soluble in water (10 mg/ml). "Shiga T, Wajima Z, Inoue T, et al. Aprotinin in major orthopedic surgery: a systematic review of randomized controlled trials. Anesth Analg. 2005 Dec;101(6):1602-7. PMID: 16301226.

 

Mahdy AM, Webster NR. Perioperative systemic haemostatic agents. Br J Anaesth. 2004 Dec;93(6):842-58. PMID: 15277296.

 

Kassell B, Laskowski M Sr. The basic trypsin inhibitor of bovine pancreas. V. The disulfide linkages. Biochem Biophys Res Commun. 1965 Aug 16;20(4):463-8. PMID: 5860161.

" Xn Not dangerous goods.

LKT A6268 Aprotinin 50 mg 434.9 Polypeptide; serine protease inhibitor. Pancreatic trypsin inhibitor; Antagosan; Fosten; Iniprol; Repulson; Trazinin; Zymofren 9087-70-1 ≥98% 6511.44 C284H432N84O79S7 CCC(C)C1C(=O)NC(C(=O)NC(C(=O)NC(C(=O)NC(C(=O)NC(C(=O)NC(C(=O)NC(C(=O)NC(C(=O)NC(C(=O)NCC(=O)NC(C(=O)NC2CSSCC3C(=O)NC(C(=O)NC(C(=O)NC(C(=O)NC(CSSCC(C(=O)NC(C(=O)NC(C(=O)N4CCCC4C(=O)N5CCCC5C(=O)NC(C(=O)NC(C(=O)NCC(=O)N6CCCC6C(=O)NC(CSSCC(C(=O)NC(C(=O)NC(C(=O)NC(C(=O)NC(C(=O)NC(C(=O)NC(C(=O)NC(C(=O)NC(C(=O)NC(C(=O)NC(C(=O)NC(C(=O)NC(C(=O)N3)CC(=O)O)CCC(=O)O)C)CO)CCCCN)CC7=CC=CC=C7)CC(=O)N)CC(=O)N)CCCNC(=N)N)CCCCN)C)CCCNC(=N)N)NC(=O)CNC(=O)CNC(=O)C(NC(=O)C(NC(=O)C(NC(=O)C(NC(=O)C(NC2=O)CCC(=O)N)C(C)O)CC8=CC=CC=C8)C(C)C)CC9=CC=C(C=C9)O)C(=O)NC(C(=O)NC(C(=O)NC(C(=O)N1)CCCNC(=N)N)C)CCCCN)C(C)O)CC1=CC=C(C=C1)O)CCC(=O)O)CC(C)C)NC(=O)C(CC1=CC=CC=C1)NC(=O)C(CC(=O)O)NC(=O)C1CCCN1C(=O)C(CCCNC(=N)N)N)C(=O)NCC(=O)NCC(=O)NC(C)C(=O)O)C(C)O)CCCNC(=N)N)CCSC)CC(C)C)C)CCCCN)C)CC(=O)N)CC1=CC=C(C=C1)O)CC1=CC=CC=C1)CC1=CC=C(C=C1)O)CCCNC(=N)N)C(C)CC Protect from moisture. Ambient 4°C Soluble in water (10 mg/ml). "Shiga T, Wajima Z, Inoue T, et al. Aprotinin in major orthopedic surgery: a systematic review of randomized controlled trials. Anesth Analg. 2005 Dec;101(6):1602-7. PMID: 16301226.

 

Mahdy AM, Webster NR. Perioperative systemic haemostatic agents. Br J Anaesth. 2004 Dec;93(6):842-58. PMID: 15277296.

 

Kassell B, Laskowski M Sr. The basic trypsin inhibitor of bovine pancreas. V. The disulfide linkages. Biochem Biophys Res Commun. 1965 Aug 16;20(4):463-8. PMID: 5860161.

" Xn Not dangerous goods.

LKT A6368 Aprepitant 5 mg 133.9 NK1 antagonist. 5-[[(2R,3S)-2-[(1R)-1-[3,5-Bis(trifluoromethyl)phenyl]ethoxy]-3-(4-fluorophenyl)-4-morpholinyl]methyl]-1,2-dihydro-3H-1,2,4-triazol-3-one (2R)-[(1R)-3,5-bis(trifluoromethyl)phenylethoxy]-(3S)-(4-fluoro)phenyl-4-(3-oxo-1,2,4-triazol-5-yl)methyl morpholine 170729-80-3 ≥98% 534.43 C23H21F7N4O3 CC(C1=CC(=CC(=C1)C(F)(F)F)C(F)(F)F)OC2C(N(CCO2)CC3=NC(=O)NN3)C4=CC=C(C=C4)F Ambient Ambient "Muñoz M, Martinez-Armesto J, Coveñas R. NK-1 receptor antagonists as antitumor drugs: a survey of the literature from 2000 to 2011. Expert Opin Ther Pat. 2012 Jul;22(7):735-46. PMID: 22697287.

 

Massaro AM, Lenz KL. Aprepitant: a novel antiemetic for chemotherapy-induced nausea and vomiting. Ann Pharmacother. 2005 Jan;39(1):77-85. PMID: 15562136.

 

Kramer MS, Cutler N, Feighner J, et al. Distinct mechanism for antidepressant activity by blockade of central substance P receptors. Science. 1998 Sep 11;281(5383):1640-5. PMID: 9733503.

" Not dangerous goods.

LKT A6368 Aprepitant 10 mg 200.8 NK1 antagonist. 5-[[(2R,3S)-2-[(1R)-1-[3,5-Bis(trifluoromethyl)phenyl]ethoxy]-3-(4-fluorophenyl)-4-morpholinyl]methyl]-1,2-dihydro-3H-1,2,4-triazol-3-one (2R)-[(1R)-3,5-bis(trifluoromethyl)phenylethoxy]-(3S)-(4-fluoro)phenyl-4-(3-oxo-1,2,4-triazol-5-yl)methyl morpholine 170729-80-3 ≥98% 534.43 C23H21F7N4O3 CC(C1=CC(=CC(=C1)C(F)(F)F)C(F)(F)F)OC2C(N(CCO2)CC3=NC(=O)NN3)C4=CC=C(C=C4)F Ambient Ambient "Muñoz M, Martinez-Armesto J, Coveñas R. NK-1 receptor antagonists as antitumor drugs: a survey of the literature from 2000 to 2011. Expert Opin Ther Pat. 2012 Jul;22(7):735-46. PMID: 22697287.

 

Massaro AM, Lenz KL. Aprepitant: a novel antiemetic for chemotherapy-induced nausea and vomiting. Ann Pharmacother. 2005 Jan;39(1):77-85. PMID: 15562136.

 

Kramer MS, Cutler N, Feighner J, et al. Distinct mechanism for antidepressant activity by blockade of central substance P receptors. Science. 1998 Sep 11;281(5383):1640-5. PMID: 9733503.

" Not dangerous goods.

LKT A6368 Aprepitant 25 mg 410.1 NK1 antagonist. 5-[[(2R,3S)-2-[(1R)-1-[3,5-Bis(trifluoromethyl)phenyl]ethoxy]-3-(4-fluorophenyl)-4-morpholinyl]methyl]-1,2-dihydro-3H-1,2,4-triazol-3-one (2R)-[(1R)-3,5-bis(trifluoromethyl)phenylethoxy]-(3S)-(4-fluoro)phenyl-4-(3-oxo-1,2,4-triazol-5-yl)methyl morpholine 170729-80-3 ≥98% 534.43 C23H21F7N4O3 CC(C1=CC(=CC(=C1)C(F)(F)F)C(F)(F)F)OC2C(N(CCO2)CC3=NC(=O)NN3)C4=CC=C(C=C4)F Ambient Ambient "Muñoz M, Martinez-Armesto J, Coveñas R. NK-1 receptor antagonists as antitumor drugs: a survey of the literature from 2000 to 2011. Expert Opin Ther Pat. 2012 Jul;22(7):735-46. PMID: 22697287.

 

Massaro AM, Lenz KL. Aprepitant: a novel antiemetic for chemotherapy-induced nausea and vomiting. Ann Pharmacother. 2005 Jan;39(1):77-85. PMID: 15562136.

 

Kramer MS, Cutler N, Feighner J, et al. Distinct mechanism for antidepressant activity by blockade of central substance P receptors. Science. 1998 Sep 11;281(5383):1640-5. PMID: 9733503.

" Not dangerous goods.

LKT A6804 Arbutin 5 g 61.1 Glycoside hydroquinone originally found in Bergenia and Arctostaphylos; PLA2 and tyrosinase inhibitor. 4-Hydroxyphenyl-β-D-glucopyranoside Hydroquinone glucose; Arbutoside; Ursin 497-76-7 ≥98% 272.25 C12H16O7 C1=CC(=CC=C1O)OC2C(C(C(C(O2)CO)O)O)O Ambient Ambient Soluble in water (55mg/mL), DMSO (55mg/mL)  and alcohol. "Inoue Y, Hasegawa S, Yamada T, et al. Analysis of the effects of hydroquinone and arbutin on the differentiation of melanocytes. Biol Pharm Bull. 2013;36(11):1722-30. PMID: 24189417.

 

Lim YJ, Lee EH, Kang TH, et al. Inhibitory effects of arbutin on melanin biosynthesis of alpha-melanocyte stimulating hormone-induced hyperpigmentation in cultured brownish guinea pig skin tissues. Arch Pharm Res. 2009 Mar;32(3):367-73. PMID: 19387580.

 

Oliver AE, Crowe LM, de Araujo PS, et al. Arbutin inhibits PLA2 in partially hydrated model systems. Biochim Biophys Acta. 1996 Jul 12;1302(1):69-78. PMID: 8695657.

" Xn Xi Not dangerous goods.

LKT A6804 Arbutin 10 g 101.9 Glycoside hydroquinone originally found in Bergenia and Arctostaphylos; PLA2 and tyrosinase inhibitor. 4-Hydroxyphenyl-β-D-glucopyranoside Hydroquinone glucose; Arbutoside; Ursin 497-76-7 ≥98% 272.25 C12H16O7 C1=CC(=CC=C1O)OC2C(C(C(C(O2)CO)O)O)O Ambient Ambient Soluble in water (55mg/mL), DMSO (55mg/mL)  and alcohol. "Inoue Y, Hasegawa S, Yamada T, et al. Analysis of the effects of hydroquinone and arbutin on the differentiation of melanocytes. Biol Pharm Bull. 2013;36(11):1722-30. PMID: 24189417.

 

Lim YJ, Lee EH, Kang TH, et al. Inhibitory effects of arbutin on melanin biosynthesis of alpha-melanocyte stimulating hormone-induced hyperpigmentation in cultured brownish guinea pig skin tissues. Arch Pharm Res. 2009 Mar;32(3):367-73. PMID: 19387580.

 

Oliver AE, Crowe LM, de Araujo PS, et al. Arbutin inhibits PLA2 in partially hydrated model systems. Biochim Biophys Acta. 1996 Jul 12;1302(1):69-78. PMID: 8695657.

" Xn Xi Not dangerous goods.

LKT A6804 Arbutin 25 g 203.8 Glycoside hydroquinone originally found in Bergenia and Arctostaphylos; PLA2 and tyrosinase inhibitor. 4-Hydroxyphenyl-β-D-glucopyranoside Hydroquinone glucose; Arbutoside; Ursin 497-76-7 ≥98% 272.25 C12H16O7 C1=CC(=CC=C1O)OC2C(C(C(C(O2)CO)O)O)O Ambient Ambient Soluble in water (55mg/mL), DMSO (55mg/mL)  and alcohol. "Inoue Y, Hasegawa S, Yamada T, et al. Analysis of the effects of hydroquinone and arbutin on the differentiation of melanocytes. Biol Pharm Bull. 2013;36(11):1722-30. PMID: 24189417.

 

Lim YJ, Lee EH, Kang TH, et al. Inhibitory effects of arbutin on melanin biosynthesis of alpha-melanocyte stimulating hormone-induced hyperpigmentation in cultured brownish guinea pig skin tissues. Arch Pharm Res. 2009 Mar;32(3):367-73. PMID: 19387580.

 

Oliver AE, Crowe LM, de Araujo PS, et al. Arbutin inhibits PLA2 in partially hydrated model systems. Biochim Biophys Acta. 1996 Jul 12;1302(1):69-78. PMID: 8695657.

" Xn Xi Not dangerous goods.

LKT A6823 Argatroban 10 mg 136 Thrombin inhibitor. "(2R,4R)-4-Methyl-1-((S)-N(sup2)-(((RS)-1,2,3,4- tetrahydro-3-methyl-8-quinolyl)sulfonyl)arginyl)- pipecolic acid 

" Argatrobanum 74863-84-6 ≥98% 508.64 C23H36N6O5S CC1CCN(C(C1)C(=O)O)C(=O)C(CCCN=C(N)N)NS(=O)(=O)C2=CC=CC3=C2NCC(C3)C Ambient Ambient Soluble in ethanol. "Tardy-Poncet B, Combe M, Piot M, et al. Effects of argatroban, danaparoid, and fondaparinux on trombin generation in heparin-induced thrombocytopenia. Thromb Haemost. 2013 Mar;109(3):504-9. PMID: 23328916.

 

Cruz-González I, López-Jiménez R, Perez-Rivera A, et al. Pharmacokinetic evaluation of argatroban for the treatment of acute coronary syndrome. Expert Opin Drug Metab Toxicol. 2012 Nov;8(11):1483-93. PMID: 22970706.

" None Not dangerous goods.

LKT A6823 Argatroban 25 mg 271.7 Thrombin inhibitor. "(2R,4R)-4-Methyl-1-((S)-N(sup2)-(((RS)-1,2,3,4- tetrahydro-3-methyl-8-quinolyl)sulfonyl)arginyl)- pipecolic acid 

" Argatrobanum 74863-84-6 ≥98% 508.64 C23H36N6O5S CC1CCN(C(C1)C(=O)O)C(=O)C(CCCN=C(N)N)NS(=O)(=O)C2=CC=CC3=C2NCC(C3)C Ambient Ambient Soluble in ethanol. "Tardy-Poncet B, Combe M, Piot M, et al. Effects of argatroban, danaparoid, and fondaparinux on trombin generation in heparin-induced thrombocytopenia. Thromb Haemost. 2013 Mar;109(3):504-9. PMID: 23328916.

 

Cruz-González I, López-Jiménez R, Perez-Rivera A, et al. Pharmacokinetic evaluation of argatroban for the treatment of acute coronary syndrome. Expert Opin Drug Metab Toxicol. 2012 Nov;8(11):1483-93. PMID: 22970706.

" None Not dangerous goods.

LKT A6823 Argatroban 100 mg 883.3 Thrombin inhibitor. "(2R,4R)-4-Methyl-1-((S)-N(sup2)-(((RS)-1,2,3,4- tetrahydro-3-methyl-8-quinolyl)sulfonyl)arginyl)- pipecolic acid 

" Argatrobanum 74863-84-6 ≥98% 508.64 C23H36N6O5S CC1CCN(C(C1)C(=O)O)C(=O)C(CCCN=C(N)N)NS(=O)(=O)C2=CC=CC3=C2NCC(C3)C Ambient Ambient Soluble in ethanol. "Tardy-Poncet B, Combe M, Piot M, et al. Effects of argatroban, danaparoid, and fondaparinux on trombin generation in heparin-induced thrombocytopenia. Thromb Haemost. 2013 Mar;109(3):504-9. PMID: 23328916.

 

Cruz-González I, López-Jiménez R, Perez-Rivera A, et al. Pharmacokinetic evaluation of argatroban for the treatment of acute coronary syndrome. Expert Opin Drug Metab Toxicol. 2012 Nov;8(11):1483-93. PMID: 22970706.

" None Not dangerous goods.

LKT A6825 L-Arginine 25 g 27.2 Endogenous amino acid, also found in meat, dairy, grains, legumes, NO precursor. Arginine; Arg; R; 2-amino-5-guanidinovaleric acid; (S)-2-amino-5-[(aminoiminomethyl)-amino]pentanoic acid 74-79-3 ≥98% 174.2 C6H14N4O2 C(CC(C(=O)O)N)CN=C(N)N Aqueous solutions absorb CO2. Ambient 4°C Soluble in water (50mg/mL). Sparingly soluble in alcohol. Insoluble in ether.  "Dong JY, Qin LQ, Zhang Z, et al. Effect of oral L-arginine supplementation on blood pressure: a meta-analysis of randomized, double-blind, placebo-controlled trials. Am Heart J. 2011 Dec;162(6):959-65. PMID: 22137067.

 

Stechmiller JK, Childress B, Cowan L. Arginine supplementation and wound healing. Nutr Clin Pract. 2005 Feb;20(1):52-61. PMID: 16207646.

 

Gokce N. L-arginine and hypertension. J Nutr. 2004 Oct;134(10 Suppl):2807S-2811S. PMID: 15465790.

" Xn, Xi Not dangerous goods.

LKT A6825 L-Arginine 100 g 54.4 Endogenous amino acid, also found in meat, dairy, grains, legumes, NO precursor. Arginine; Arg; R; 2-amino-5-guanidinovaleric acid; (S)-2-amino-5-[(aminoiminomethyl)-amino]pentanoic acid 74-79-3 ≥98% 174.2 C6H14N4O2 C(CC(C(=O)O)N)CN=C(N)N Aqueous solutions absorb CO2. Ambient 4°C Soluble in water (50mg/mL). Sparingly soluble in alcohol. Insoluble in ether.  "Dong JY, Qin LQ, Zhang Z, et al. Effect of oral L-arginine supplementation on blood pressure: a meta-analysis of randomized, double-blind, placebo-controlled trials. Am Heart J. 2011 Dec;162(6):959-65. PMID: 22137067.

 

Stechmiller JK, Childress B, Cowan L. Arginine supplementation and wound healing. Nutr Clin Pract. 2005 Feb;20(1):52-61. PMID: 16207646.

 

Gokce N. L-arginine and hypertension. J Nutr. 2004 Oct;134(10 Suppl):2807S-2811S. PMID: 15465790.

" Xn, Xi Not dangerous goods.

LKT A6825 L-Arginine 500 g 136 Endogenous amino acid, also found in meat, dairy, grains, legumes, NO precursor. Arginine; Arg; R; 2-amino-5-guanidinovaleric acid; (S)-2-amino-5-[(aminoiminomethyl)-amino]pentanoic acid 74-79-3 ≥98% 174.2 C6H14N4O2 C(CC(C(=O)O)N)CN=C(N)N Aqueous solutions absorb CO2. Ambient 4°C Soluble in water (50mg/mL). Sparingly soluble in alcohol. Insoluble in ether.  "Dong JY, Qin LQ, Zhang Z, et al. Effect of oral L-arginine supplementation on blood pressure: a meta-analysis of randomized, double-blind, placebo-controlled trials. Am Heart J. 2011 Dec;162(6):959-65. PMID: 22137067.

 

Stechmiller JK, Childress B, Cowan L. Arginine supplementation and wound healing. Nutr Clin Pract. 2005 Feb;20(1):52-61. PMID: 16207646.

 

Gokce N. L-arginine and hypertension. J Nutr. 2004 Oct;134(10 Suppl):2807S-2811S. PMID: 15465790.

" Xn, Xi Not dangerous goods.

LKT A6826 L-Arginine Hydrochloride 25 g 20.4 Endogenous amino acid, also found in meat, dairy, grains, legumes, NO precursor. Arginine hydrochloride 1119-34-2 ≥98% 210.66 C6H14N4O2 HCl C(CC(C(=O)O)N)CN=C(N)N.Cl Ambient Ambient Soluble in water. Slightly soluble in hot alcohol. "Dong JY, Qin LQ, Zhang Z, et al. Effect of oral L-arginine supplementation on blood pressure: a meta-analysis of randomized, double-blind, placebo-controlled trials. Am Heart J. 2011 Dec;162(6):959-65. PMID: 22137067.

 

Stechmiller JK, Childress B, Cowan L. Arginine supplementation and wound healing. Nutr Clin Pract. 2005 Feb;20(1):52-61. PMID: 16207646.

 

Gokce N. L-arginine and hypertension. J Nutr. 2004 Oct;134(10 Suppl):2807S-2811S. PMID: 15465790.

" Xn, Xi Not dangerous goods.

LKT A6826 L-Arginine Hydrochloride 100 g 36.6 Endogenous amino acid, also found in meat, dairy, grains, legumes, NO precursor. Arginine hydrochloride 1119-34-2 ≥98% 210.66 C6H14N4O2 HCl C(CC(C(=O)O)N)CN=C(N)N.Cl Ambient Ambient Soluble in water. Slightly soluble in hot alcohol. "Dong JY, Qin LQ, Zhang Z, et al. Effect of oral L-arginine supplementation on blood pressure: a meta-analysis of randomized, double-blind, placebo-controlled trials. Am Heart J. 2011 Dec;162(6):959-65. PMID: 22137067.

 

Stechmiller JK, Childress B, Cowan L. Arginine supplementation and wound healing. Nutr Clin Pract. 2005 Feb;20(1):52-61. PMID: 16207646.

 

Gokce N. L-arginine and hypertension. J Nutr. 2004 Oct;134(10 Suppl):2807S-2811S. PMID: 15465790.

" Xn, Xi Not dangerous goods.

LKT A6826 L-Arginine Hydrochloride 500 g 136 Endogenous amino acid, also found in meat, dairy, grains, legumes, NO precursor. Arginine hydrochloride 1119-34-2 ≥98% 210.66 C6H14N4O2 HCl C(CC(C(=O)O)N)CN=C(N)N.Cl Ambient Ambient Soluble in water. Slightly soluble in hot alcohol. "Dong JY, Qin LQ, Zhang Z, et al. Effect of oral L-arginine supplementation on blood pressure: a meta-analysis of randomized, double-blind, placebo-controlled trials. Am Heart J. 2011 Dec;162(6):959-65. PMID: 22137067.

 

Stechmiller JK, Childress B, Cowan L. Arginine supplementation and wound healing. Nutr Clin Pract. 2005 Feb;20(1):52-61. PMID: 16207646.

 

Gokce N. L-arginine and hypertension. J Nutr. 2004 Oct;134(10 Suppl):2807S-2811S. PMID: 15465790.

" Xn, Xi Not dangerous goods.

LKT A6828 N(α),N(α)-Dimethyl-L-Arginine Ammonium 10 mg 33.8 Endogenous amino acid derivative, regulates water/Na+ homeostasis; NOS inhibitor. ≥98% 219.28 C8H18N4O2 NH3 Ambient -20°C "Mauricio MD, Aldasoro M, Ortega J, et al. Endothelial dysfunction in morbid obesity. Curr Pharm Des. 2013;19(32):5718-29. PMID: 23448493.

 

Szlachcic A, Krzysiek-Maczka G, Pajdo R, et al. The impact of asymmetric dimethylarginine (ADAMA), the endogenous nitric oxide (NO) synthase inhibitor, to the pathogenesis of gastric mucosal damage. Curr Pharm Des. 2013;19(1):90-7. PMID: 22950506.

 

Twardowski ZJ. Sodium, hypertension, and an explanation of the ""lag phenomenon"" in hemodialysis patients. Hemodial Int. 2008 Oct;12(4):412-25. PMID: 19090863.

 

Surdacki A. L-arginine analogs--inactive markers or active agents in atherogenesis? Cardiovasc Hematol Agents Med Chem. 2008 Oct;6(4):302-11. PMID: 18855643.

"

LKT A6828 N(α),N(α)-Dimethyl-L-Arginine Ammonium 25 mg 70.2 Endogenous amino acid derivative, regulates water/Na+ homeostasis; NOS inhibitor. ≥98% 219.28 C8H18N4O2 NH3 Ambient -20°C "Mauricio MD, Aldasoro M, Ortega J, et al. Endothelial dysfunction in morbid obesity. Curr Pharm Des. 2013;19(32):5718-29. PMID: 23448493.

 

Szlachcic A, Krzysiek-Maczka G, Pajdo R, et al. The impact of asymmetric dimethylarginine (ADAMA), the endogenous nitric oxide (NO) synthase inhibitor, to the pathogenesis of gastric mucosal damage. Curr Pharm Des. 2013;19(1):90-7. PMID: 22950506.

 

Twardowski ZJ. Sodium, hypertension, and an explanation of the ""lag phenomenon"" in hemodialysis patients. Hemodial Int. 2008 Oct;12(4):412-25. PMID: 19090863.

 

Surdacki A. L-arginine analogs--inactive markers or active agents in atherogenesis? Cardiovasc Hematol Agents Med Chem. 2008 Oct;6(4):302-11. PMID: 18855643.

"

LKT A6828 N(α),N(α)-Dimethyl-L-Arginine Ammonium 100 mg 234.5 Endogenous amino acid derivative, regulates water/Na+ homeostasis; NOS inhibitor. ≥98% 219.28 C8H18N4O2 NH3 Ambient -20°C "Mauricio MD, Aldasoro M, Ortega J, et al. Endothelial dysfunction in morbid obesity. Curr Pharm Des. 2013;19(32):5718-29. PMID: 23448493.

 

Szlachcic A, Krzysiek-Maczka G, Pajdo R, et al. The impact of asymmetric dimethylarginine (ADAMA), the endogenous nitric oxide (NO) synthase inhibitor, to the pathogenesis of gastric mucosal damage. Curr Pharm Des. 2013;19(1):90-7. PMID: 22950506.

 

Twardowski ZJ. Sodium, hypertension, and an explanation of the ""lag phenomenon"" in hemodialysis patients. Hemodial Int. 2008 Oct;12(4):412-25. PMID: 19090863.

 

Surdacki A. L-arginine analogs--inactive markers or active agents in atherogenesis? Cardiovasc Hematol Agents Med Chem. 2008 Oct;6(4):302-11. PMID: 18855643.

"

LKT A6922 Arformoterol Tartrate 5 mg 242.7 R,R enantiomer of formoterol; β2-adrenergic and TAS2R agonist. 200815-49-2 ≥98% 494.19 C19H24N2O4 CC(CC1=CC=C(C=C1)OC)NCC(C2=CC(=C(C=C2)O)NC=O)O.C(C(C(=O)O)O)(C(=O)O)O Ambient Ambient "Grassin-Delyle S, Abrial C, Fayad-Kobeissi S, et al. The expression and relaxant effect of bitter taste receptors in human bronchi. Respir Res. 2013 Nov 22;14:134. PMID: 24266887.

 

Goncharova EA, Goncharov DA, Zhao H, et al. β2-adrenergic receptor agonists modulate human airway smooth muscle cell migration via vasodilator-stimulated phosphoprotein. Am J Respir Cell Mol Biol. 2012 Jan;46(1):48-54. PMID: 22210825.

 

Mercado N, To Y, Kobayashi Y, et al. p38 mitogen-activated protein kinase-γ inhibition by long-acting β2 adrenergic agonists reversed steroid insensitivity in severe asthma. Mol Pharmacol. 2011 Dec;80(6):1128-35. PMID: 21917909.

 

Johnson M. Beta2-adrenoceptors: mechanisms of action of beta2-agonists. Paediatr Respir Rev. 2001 Mar;2(1):57-62. PMID: 16263481.

" Not dangerous goods.

LKT A6922 Arformoterol Tartrate 10 mg 418.6 R,R enantiomer of formoterol; β2-adrenergic and TAS2R agonist. 200815-49-2 ≥98% 494.19 C19H24N2O4 CC(CC1=CC=C(C=C1)OC)NCC(C2=CC(=C(C=C2)O)NC=O)O.C(C(C(=O)O)O)(C(=O)O)O Ambient Ambient "Grassin-Delyle S, Abrial C, Fayad-Kobeissi S, et al. The expression and relaxant effect of bitter taste receptors in human bronchi. Respir Res. 2013 Nov 22;14:134. PMID: 24266887.

 

Goncharova EA, Goncharov DA, Zhao H, et al. β2-adrenergic receptor agonists modulate human airway smooth muscle cell migration via vasodilator-stimulated phosphoprotein. Am J Respir Cell Mol Biol. 2012 Jan;46(1):48-54. PMID: 22210825.

 

Mercado N, To Y, Kobayashi Y, et al. p38 mitogen-activated protein kinase-γ inhibition by long-acting β2 adrenergic agonists reversed steroid insensitivity in severe asthma. Mol Pharmacol. 2011 Dec;80(6):1128-35. PMID: 21917909.

 

Johnson M. Beta2-adrenoceptors: mechanisms of action of beta2-agonists. Paediatr Respir Rev. 2001 Mar;2(1):57-62. PMID: 16263481.

" Not dangerous goods.

LKT A6922 Arformoterol Tartrate 25 mg 803.8 R,R enantiomer of formoterol; β2-adrenergic and TAS2R agonist. 200815-49-2 ≥98% 494.19 C19H24N2O4 CC(CC1=CC=C(C=C1)OC)NCC(C2=CC(=C(C=C2)O)NC=O)O.C(C(C(=O)O)O)(C(=O)O)O Ambient Ambient "Grassin-Delyle S, Abrial C, Fayad-Kobeissi S, et al. The expression and relaxant effect of bitter taste receptors in human bronchi. Respir Res. 2013 Nov 22;14:134. PMID: 24266887.

 

Goncharova EA, Goncharov DA, Zhao H, et al. β2-adrenergic receptor agonists modulate human airway smooth muscle cell migration via vasodilator-stimulated phosphoprotein. Am J Respir Cell Mol Biol. 2012 Jan;46(1):48-54. PMID: 22210825.

 

Mercado N, To Y, Kobayashi Y, et al. p38 mitogen-activated protein kinase-γ inhibition by long-acting β2 adrenergic agonists reversed steroid insensitivity in severe asthma. Mol Pharmacol. 2011 Dec;80(6):1128-35. PMID: 21917909.

 

Johnson M. Beta2-adrenoceptors: mechanisms of action of beta2-agonists. Paediatr Respir Rev. 2001 Mar;2(1):57-62. PMID: 16263481.

" Not dangerous goods.

LKT A6932 Aristolochic Acid A 1 mg 81.6 Found in Aristolochia and Radix; PLA2 inhibitor, carcinogen. 8-Methoxy-3,4-methylenedioxy-10-nitrophenanthrene-1-carboxylic acid Aristolochic acid; Aristolochin Birthwort; Tardolyt 313-67-7 ≥95% 341.27 C17H11NO7 COC1=CC=CC2=C3C(=C(C=C21)[N+](=O)[O-])C(=CC4=C3OCO4)C(=O)O Ambient -20°C Soluble in DMSO or ethanol. "Chen WY, Ni Y, Pan YM, et al. GABA, progesterone and zona pellucida activation of PLA2 and regulation by MEK-ERK1/2 during acrosomal exocytosis in guinea pig spermatozoa. FEBS Lett. 2005 Aug 29;579(21):4692-700. PMID: 16098515.

 

Stiborová M, Frei E, Sopko B, et al. Human cytosolic enzymes involved in the metabolic activation of carcinogenic aristolochic acid: evidence for reductive activation by human NAD(P)H:quinone oxidoreductase. Carcinogenesis. 2003 Oct;24(10):1695-703. PMID: 12869422.

" T "UN number: 1544     Class:  6.1     Packing group:  III

Proper shipping name:  Alkaloids, solid, n.o.s. (Aristolochic Acid A)     Marine pollutant:  No     Poison Inhalation Hazard:  No."

LKT A6932 Aristolochic Acid A 5 mg 339.8 Found in Aristolochia and Radix; PLA2 inhibitor, carcinogen. 8-Methoxy-3,4-methylenedioxy-10-nitrophenanthrene-1-carboxylic acid Aristolochic acid; Aristolochin Birthwort; Tardolyt 313-67-7 ≥95% 341.27 C17H11NO7 COC1=CC=CC2=C3C(=C(C=C21)[N+](=O)[O-])C(=CC4=C3OCO4)C(=O)O Ambient -20°C Soluble in DMSO or ethanol. "Chen WY, Ni Y, Pan YM, et al. GABA, progesterone and zona pellucida activation of PLA2 and regulation by MEK-ERK1/2 during acrosomal exocytosis in guinea pig spermatozoa. FEBS Lett. 2005 Aug 29;579(21):4692-700. PMID: 16098515.

 

Stiborová M, Frei E, Sopko B, et al. Human cytosolic enzymes involved in the metabolic activation of carcinogenic aristolochic acid: evidence for reductive activation by human NAD(P)H:quinone oxidoreductase. Carcinogenesis. 2003 Oct;24(10):1695-703. PMID: 12869422.

" T "UN number: 1544     Class:  6.1     Packing group:  III

Proper shipping name:  Alkaloids, solid, n.o.s. (Aristolochic Acid A)     Marine pollutant:  No     Poison Inhalation Hazard:  No."

LKT A6932 Aristolochic Acid A 10 mg 434.9 Found in Aristolochia and Radix; PLA2 inhibitor, carcinogen. 8-Methoxy-3,4-methylenedioxy-10-nitrophenanthrene-1-carboxylic acid Aristolochic acid; Aristolochin Birthwort; Tardolyt 313-67-7 ≥95% 341.27 C17H11NO7 COC1=CC=CC2=C3C(=C(C=C21)[N+](=O)[O-])C(=CC4=C3OCO4)C(=O)O Ambient -20°C Soluble in DMSO or ethanol. "Chen WY, Ni Y, Pan YM, et al. GABA, progesterone and zona pellucida activation of PLA2 and regulation by MEK-ERK1/2 during acrosomal exocytosis in guinea pig spermatozoa. FEBS Lett. 2005 Aug 29;579(21):4692-700. PMID: 16098515.

 

Stiborová M, Frei E, Sopko B, et al. Human cytosolic enzymes involved in the metabolic activation of carcinogenic aristolochic acid: evidence for reductive activation by human NAD(P)H:quinone oxidoreductase. Carcinogenesis. 2003 Oct;24(10):1695-703. PMID: 12869422.

" T "UN number: 1544     Class:  6.1     Packing group:  III

Proper shipping name:  Alkaloids, solid, n.o.s. (Aristolochic Acid A)     Marine pollutant:  No     Poison Inhalation Hazard:  No."

LKT A6933 Aristolochic Acid B 1 mg 81.6 Found in Aristolochia and Radix; potential PLA2 inhibitor, carcinogen. 6-Nitrophenanthro(3,4-d)-1,3-dioxole-5-carboxylic acid IIBRN 0329754; CCRIS 6497 475-80-9 ≥95% 311.25 C16H9NO6 C1OC2=C(O1)C3=C(C(=C2)C(=O)O)C(=CC4=CC=CC=C43)[N+](=O)[O-] Ambient -20°C Soluble in DMSO or ethanol. "Liu Y, Han S, Feng Q, et al. Determination of aristolochic acids A and B in Chinese herbals and traditional Chinese patent medicines using ultra high performance liquid chromatography-triple quadrupole mass spectrometry. Se Pu. 2011 Nov;29(11):1076-81. PMID: 22393694.

 

Stiborová M, Frei E, Sopko B, et al. Human cytosolic enzymes involved in the metabolic activation of carcinogenic aristolochic acid: evidence for reductive activation by human NAD(P)H:quinone oxidoreductase. Carcinogenesis. 2003 Oct;24(10):1695-703. PMID: 12869422.

" "UN number: 1544     Class:  6.1     Packing group:  III

Proper shipping name:  Alkaloids, solid, n.o.s. (Aristolochic Acid B)     Marine pollutant:  No     Poison Inhalation Hazard:  No."

LKT A6933 Aristolochic Acid B 5 mg 339.8 Found in Aristolochia and Radix; potential PLA2 inhibitor, carcinogen. 6-Nitrophenanthro(3,4-d)-1,3-dioxole-5-carboxylic acid IIBRN 0329754; CCRIS 6497 475-80-9 ≥95% 311.25 C16H9NO6 C1OC2=C(O1)C3=C(C(=C2)C(=O)O)C(=CC4=CC=CC=C43)[N+](=O)[O-] Ambient -20°C Soluble in DMSO or ethanol. "Liu Y, Han S, Feng Q, et al. Determination of aristolochic acids A and B in Chinese herbals and traditional Chinese patent medicines using ultra high performance liquid chromatography-triple quadrupole mass spectrometry. Se Pu. 2011 Nov;29(11):1076-81. PMID: 22393694.

 

Stiborová M, Frei E, Sopko B, et al. Human cytosolic enzymes involved in the metabolic activation of carcinogenic aristolochic acid: evidence for reductive activation by human NAD(P)H:quinone oxidoreductase. Carcinogenesis. 2003 Oct;24(10):1695-703. PMID: 12869422.

" "UN number: 1544     Class:  6.1     Packing group:  III

Proper shipping name:  Alkaloids, solid, n.o.s. (Aristolochic Acid B)     Marine pollutant:  No     Poison Inhalation Hazard:  No."

LKT A6933 Aristolochic Acid B 10 mg 434.9 Found in Aristolochia and Radix; potential PLA2 inhibitor, carcinogen. 6-Nitrophenanthro(3,4-d)-1,3-dioxole-5-carboxylic acid IIBRN 0329754; CCRIS 6497 475-80-9 ≥95% 311.25 C16H9NO6 C1OC2=C(O1)C3=C(C(=C2)C(=O)O)C(=CC4=CC=CC=C43)[N+](=O)[O-] Ambient -20°C Soluble in DMSO or ethanol. "Liu Y, Han S, Feng Q, et al. Determination of aristolochic acids A and B in Chinese herbals and traditional Chinese patent medicines using ultra high performance liquid chromatography-triple quadrupole mass spectrometry. Se Pu. 2011 Nov;29(11):1076-81. PMID: 22393694.

 

Stiborová M, Frei E, Sopko B, et al. Human cytosolic enzymes involved in the metabolic activation of carcinogenic aristolochic acid: evidence for reductive activation by human NAD(P)H:quinone oxidoreductase. Carcinogenesis. 2003 Oct;24(10):1695-703. PMID: 12869422.

" "UN number: 1544     Class:  6.1     Packing group:  III

Proper shipping name:  Alkaloids, solid, n.o.s. (Aristolochic Acid B)     Marine pollutant:  No     Poison Inhalation Hazard:  No."

LKT A6934 Aristolochic Acid C 1 mg 81.6 Found in Aristolochia and Radix; potential PLA2 inhibitor, carcinogen. 4849-90-5 ≥94% 327.25 C16H9NO7 C1OC2=C(O1)C3=C4C=C(C=CC4=CC(=C3C(=C2)C(=O)O)[N+](=O)[O-])O Ambient -20°C Soluble in DMSO or ethanol. "Stiborová M, Frei E, Sopko B, et al. Human cytosolic enzymes involved in the metabolic activation of carcinogenic aristolochic acid: evidence for reductive activation by human NAD(P)H:quinone oxidoreductase. Carcinogenesis. 2003 Oct;24(10):1695-703. PMID: 12869422.

 

Wu TS, Ou LF, Teng CM. Aristolochic acids, aristolactam alkaloids and amides from Aristolochia kankauensis. Phytochemistry. 1994 Jul;36(4):1063-8. PMID: 7765207.

 

Kupchan SM, Wormser HC, Sesso M. Tumor inhibitors. XI. Proof of structure of aristolochic acid-C by total synthesis of its methyl ester methyl ether. J Org Chem. 1965 Nov;30(11):3935-7. PMID: 5846162.

" "UN number: 1544     Class:  6.1     Packing group:  III

Proper shipping name:  Alkaloids, solid, n.o.s. (Aristolochic Acid C)     Marine pollutant:  No     Poison Inhalation Hazard:  No."

LKT A6934 Aristolochic Acid C 5 mg 339.8 Found in Aristolochia and Radix; potential PLA2 inhibitor, carcinogen. 4849-90-5 ≥94% 327.25 C16H9NO7 C1OC2=C(O1)C3=C4C=C(C=CC4=CC(=C3C(=C2)C(=O)O)[N+](=O)[O-])O Ambient -20°C Soluble in DMSO or ethanol. "Stiborová M, Frei E, Sopko B, et al. Human cytosolic enzymes involved in the metabolic activation of carcinogenic aristolochic acid: evidence for reductive activation by human NAD(P)H:quinone oxidoreductase. Carcinogenesis. 2003 Oct;24(10):1695-703. PMID: 12869422.

 

Wu TS, Ou LF, Teng CM. Aristolochic acids, aristolactam alkaloids and amides from Aristolochia kankauensis. Phytochemistry. 1994 Jul;36(4):1063-8. PMID: 7765207.

 

Kupchan SM, Wormser HC, Sesso M. Tumor inhibitors. XI. Proof of structure of aristolochic acid-C by total synthesis of its methyl ester methyl ether. J Org Chem. 1965 Nov;30(11):3935-7. PMID: 5846162.

" "UN number: 1544     Class:  6.1     Packing group:  III

Proper shipping name:  Alkaloids, solid, n.o.s. (Aristolochic Acid C)     Marine pollutant:  No     Poison Inhalation Hazard:  No."

LKT A6934 Aristolochic Acid C 10 mg 434.9 Found in Aristolochia and Radix; potential PLA2 inhibitor, carcinogen. 4849-90-5 ≥94% 327.25 C16H9NO7 C1OC2=C(O1)C3=C4C=C(C=CC4=CC(=C3C(=C2)C(=O)O)[N+](=O)[O-])O Ambient -20°C Soluble in DMSO or ethanol. "Stiborová M, Frei E, Sopko B, et al. Human cytosolic enzymes involved in the metabolic activation of carcinogenic aristolochic acid: evidence for reductive activation by human NAD(P)H:quinone oxidoreductase. Carcinogenesis. 2003 Oct;24(10):1695-703. PMID: 12869422.

 

Wu TS, Ou LF, Teng CM. Aristolochic acids, aristolactam alkaloids and amides from Aristolochia kankauensis. Phytochemistry. 1994 Jul;36(4):1063-8. PMID: 7765207.

 

Kupchan SM, Wormser HC, Sesso M. Tumor inhibitors. XI. Proof of structure of aristolochic acid-C by total synthesis of its methyl ester methyl ether. J Org Chem. 1965 Nov;30(11):3935-7. PMID: 5846162.

" "UN number: 1544     Class:  6.1     Packing group:  III

Proper shipping name:  Alkaloids, solid, n.o.s. (Aristolochic Acid C)     Marine pollutant:  No     Poison Inhalation Hazard:  No."

LKT A6970 Artemether 50 mg 33.9 Sesquiterpene lactone derived from Artemesia. "(3R,5aS,6R,8aS,9R,10S,12R,12aR)-Decahydro-10-methoxy-3,6,9-

trimethyl-3,12-epoxy-12H-pyrano(4,3-j)-1,2-benzodioxepin 

" Dihydroartemisinin methyl ether; Dihydroqinghaosu methyl ether; Paluther 71963-77-4 ≥98% 298.37 C16H26O5 CC1CCC2C(C(OC3C24C1CCC(O3)(OO4)C)OC)C Ambient Ambient Insoluble in water.  Soluble in acetone and ethyl acetate. "Angus B. Novel anti-malarial combinations and their toxicity. Expert Rev Clin Pharmacol. 2014 May;7(3):299-316. PMID: 24716844.

 

Wang W, Li TY, Ji Y, et al. Efficacy of artemether and artesunate in mice infected with praziquantel non-susceptible isolate of Schistosoma japonicum. Parasitol Res. 2014 Mar;113(3):925-31. PMID: 24326467.

 

Ebrahimisadr P, Ghaffarifar F, Mohammad Hassan Z. In-vitro Evaluation of Antileishmanial Activity and Toxicity of Artemether with Focus on its Apoptotic Effect. Iran J Pharm Res. 2013 Fall;12(4):903-9. PMID: 24523770." Not dangerous goods.

LKT A6970 Artemether 100 mg 54.4 Sesquiterpene lactone derived from Artemesia. "(3R,5aS,6R,8aS,9R,10S,12R,12aR)-Decahydro-10-methoxy-3,6,9-

trimethyl-3,12-epoxy-12H-pyrano(4,3-j)-1,2-benzodioxepin 

" Dihydroartemisinin methyl ether; Dihydroqinghaosu methyl ether; Paluther 71963-77-4 ≥98% 298.37 C16H26O5 CC1CCC2C(C(OC3C24C1CCC(O3)(OO4)C)OC)C Ambient Ambient Insoluble in water.  Soluble in acetone and ethyl acetate. "Angus B. Novel anti-malarial combinations and their toxicity. Expert Rev Clin Pharmacol. 2014 May;7(3):299-316. PMID: 24716844.

 

Wang W, Li TY, Ji Y, et al. Efficacy of artemether and artesunate in mice infected with praziquantel non-susceptible isolate of Schistosoma japonicum. Parasitol Res. 2014 Mar;113(3):925-31. PMID: 24326467.

 

Ebrahimisadr P, Ghaffarifar F, Mohammad Hassan Z. In-vitro Evaluation of Antileishmanial Activity and Toxicity of Artemether with Focus on its Apoptotic Effect. Iran J Pharm Res. 2013 Fall;12(4):903-9. PMID: 24523770." Not dangerous goods.

LKT A6970 Artemether 500 mg 88.3 Sesquiterpene lactone derived from Artemesia. "(3R,5aS,6R,8aS,9R,10S,12R,12aR)-Decahydro-10-methoxy-3,6,9-

trimethyl-3,12-epoxy-12H-pyrano(4,3-j)-1,2-benzodioxepin 

" Dihydroartemisinin methyl ether; Dihydroqinghaosu methyl ether; Paluther 71963-77-4 ≥98% 298.37 C16H26O5 CC1CCC2C(C(OC3C24C1CCC(O3)(OO4)C)OC)C Ambient Ambient Insoluble in water.  Soluble in acetone and ethyl acetate. "Angus B. Novel anti-malarial combinations and their toxicity. Expert Rev Clin Pharmacol. 2014 May;7(3):299-316. PMID: 24716844.

 

Wang W, Li TY, Ji Y, et al. Efficacy of artemether and artesunate in mice infected with praziquantel non-susceptible isolate of Schistosoma japonicum. Parasitol Res. 2014 Mar;113(3):925-31. PMID: 24326467.

 

Ebrahimisadr P, Ghaffarifar F, Mohammad Hassan Z. In-vitro Evaluation of Antileishmanial Activity and Toxicity of Artemether with Focus on its Apoptotic Effect. Iran J Pharm Res. 2013 Fall;12(4):903-9. PMID: 24523770." Not dangerous goods.

LKT A6970 Artemether 1 g 129 Sesquiterpene lactone derived from Artemesia. "(3R,5aS,6R,8aS,9R,10S,12R,12aR)-Decahydro-10-methoxy-3,6,9-

trimethyl-3,12-epoxy-12H-pyrano(4,3-j)-1,2-benzodioxepin 

" Dihydroartemisinin methyl ether; Dihydroqinghaosu methyl ether; Paluther 71963-77-4 ≥98% 298.37 C16H26O5 CC1CCC2C(C(OC3C24C1CCC(O3)(OO4)C)OC)C Ambient Ambient Insoluble in water.  Soluble in acetone and ethyl acetate. "Angus B. Novel anti-malarial combinations and their toxicity. Expert Rev Clin Pharmacol. 2014 May;7(3):299-316. PMID: 24716844.

 

Wang W, Li TY, Ji Y, et al. Efficacy of artemether and artesunate in mice infected with praziquantel non-susceptible isolate of Schistosoma japonicum. Parasitol Res. 2014 Mar;113(3):925-31. PMID: 24326467.

 

Ebrahimisadr P, Ghaffarifar F, Mohammad Hassan Z. In-vitro Evaluation of Antileishmanial Activity and Toxicity of Artemether with Focus on its Apoptotic Effect. Iran J Pharm Res. 2013 Fall;12(4):903-9. PMID: 24523770." Not dangerous goods.

LKT A6979 Dihydroartemisinin 50 mg 33.9 Sesquiterpene lactone derived from Artemesia; mTORC1 inhibitor. Dihydroartemisinine; Dihydroqinghaosu; (3R,5aS,6R,8aS,9R,10S,12R,12aR)-Decahydro-3,6,9-trimethyl-3,12-epoxy-12H-pyrano[4,3-j]-1,2-benzodioxepin-10- ol 71939-50-9 ≥96% 284.35 C15H24O5 CC1CCC2C(C(OC3C24C1CCC(O3)(OO4)C)O)C Ambient Ambient Insoluble in water.   Soluble in acetone and ethanol. "Ontikatze T, Rudner J, Handrick R, et al. Dihydroartemisinin is a Hypoxia-Active Anti-Cancer Drug in Colorectal Carcinoma Cells. Front Oncol. 2014 May 19;4:116. PMID: 24904829.

 

Wanzira H, Kakuru A, Arinaitwe E, et al. Longitudinal Outcomes in a Cohort of Ugandan Children Randomized to Artemether-lumefantrine Versus Dihydroartemisinin-piperaquine for the Treatment of Malaria. Clin Infect Dis. 2014 May 13. [Epub ahead of print]. PMID: 24825870.

 

Li HJ, Xu FL, Wang YH, et al. Dihydroartemisinin: a new story of an old drug against Schistosoma mansoni infection. Parasitol Res. 2014 Jan;113(1):239-41. PMID: 24146209.

 

Flobinus A, Taudon N, Desbordes M, et al. Stability and antiviral activity against human cytomegalovirus of artemisinin derivatives. J Antimicrob Chemother. 2014 Jan;69(1):34-40. PMID: 24003183.

 

Odaka Y, Xu B, Luo Y, et al. Dihydroartemisinin inhibits the mammalian target of rapamycin-mediated signaling pathways in tumor cells. Carcinogenesis. 2014 Jan;35(1):192-200. PMID: 23929438.

 

Wei M, Xie X, Chu X, et al. Dihydroartemisinin suppresses ovalbumin-induced airway inflammation in a mouse allergic asthma model. Immunopharmacol Immunotoxicol. 2013 Jun;35(3):382-9. PMID: 23635079.

" None Not dangerous goods.

LKT A6979 Dihydroartemisinin 100 mg 54.4 Sesquiterpene lactone derived from Artemesia; mTORC1 inhibitor. Dihydroartemisinine; Dihydroqinghaosu; (3R,5aS,6R,8aS,9R,10S,12R,12aR)-Decahydro-3,6,9-trimethyl-3,12-epoxy-12H-pyrano[4,3-j]-1,2-benzodioxepin-10- ol 71939-50-9 ≥96% 284.35 C15H24O5 CC1CCC2C(C(OC3C24C1CCC(O3)(OO4)C)O)C Ambient Ambient Insoluble in water.   Soluble in acetone and ethanol. "Ontikatze T, Rudner J, Handrick R, et al. Dihydroartemisinin is a Hypoxia-Active Anti-Cancer Drug in Colorectal Carcinoma Cells. Front Oncol. 2014 May 19;4:116. PMID: 24904829.

 

Wanzira H, Kakuru A, Arinaitwe E, et al. Longitudinal Outcomes in a Cohort of Ugandan Children Randomized to Artemether-lumefantrine Versus Dihydroartemisinin-piperaquine for the Treatment of Malaria. Clin Infect Dis. 2014 May 13. [Epub ahead of print]. PMID: 24825870.

 

Li HJ, Xu FL, Wang YH, et al. Dihydroartemisinin: a new story of an old drug against Schistosoma mansoni infection. Parasitol Res. 2014 Jan;113(1):239-41. PMID: 24146209.

 

Flobinus A, Taudon N, Desbordes M, et al. Stability and antiviral activity against human cytomegalovirus of artemisinin derivatives. J Antimicrob Chemother. 2014 Jan;69(1):34-40. PMID: 24003183.

 

Odaka Y, Xu B, Luo Y, et al. Dihydroartemisinin inhibits the mammalian target of rapamycin-mediated signaling pathways in tumor cells. Carcinogenesis. 2014 Jan;35(1):192-200. PMID: 23929438.

 

Wei M, Xie X, Chu X, et al. Dihydroartemisinin suppresses ovalbumin-induced airway inflammation in a mouse allergic asthma model. Immunopharmacol Immunotoxicol. 2013 Jun;35(3):382-9. PMID: 23635079.

" None Not dangerous goods.

LKT A6979 Dihydroartemisinin 500 mg 88.3 Sesquiterpene lactone derived from Artemesia; mTORC1 inhibitor. Dihydroartemisinine; Dihydroqinghaosu; (3R,5aS,6R,8aS,9R,10S,12R,12aR)-Decahydro-3,6,9-trimethyl-3,12-epoxy-12H-pyrano[4,3-j]-1,2-benzodioxepin-10- ol 71939-50-9 ≥96% 284.35 C15H24O5 CC1CCC2C(C(OC3C24C1CCC(O3)(OO4)C)O)C Ambient Ambient Insoluble in water.   Soluble in acetone and ethanol. "Ontikatze T, Rudner J, Handrick R, et al. Dihydroartemisinin is a Hypoxia-Active Anti-Cancer Drug in Colorectal Carcinoma Cells. Front Oncol. 2014 May 19;4:116. PMID: 24904829.

 

Wanzira H, Kakuru A, Arinaitwe E, et al. Longitudinal Outcomes in a Cohort of Ugandan Children Randomized to Artemether-lumefantrine Versus Dihydroartemisinin-piperaquine for the Treatment of Malaria. Clin Infect Dis. 2014 May 13. [Epub ahead of print]. PMID: 24825870.

 

Li HJ, Xu FL, Wang YH, et al. Dihydroartemisinin: a new story of an old drug against Schistosoma mansoni infection. Parasitol Res. 2014 Jan;113(1):239-41. PMID: 24146209.

 

Flobinus A, Taudon N, Desbordes M, et al. Stability and antiviral activity against human cytomegalovirus of artemisinin derivatives. J Antimicrob Chemother. 2014 Jan;69(1):34-40. PMID: 24003183.

 

Odaka Y, Xu B, Luo Y, et al. Dihydroartemisinin inhibits the mammalian target of rapamycin-mediated signaling pathways in tumor cells. Carcinogenesis. 2014 Jan;35(1):192-200. PMID: 23929438.

 

Wei M, Xie X, Chu X, et al. Dihydroartemisinin suppresses ovalbumin-induced airway inflammation in a mouse allergic asthma model. Immunopharmacol Immunotoxicol. 2013 Jun;35(3):382-9. PMID: 23635079.

" None Not dangerous goods.

LKT A6979 Dihydroartemisinin 1 g 129 Sesquiterpene lactone derived from Artemesia; mTORC1 inhibitor. Dihydroartemisinine; Dihydroqinghaosu; (3R,5aS,6R,8aS,9R,10S,12R,12aR)-Decahydro-3,6,9-trimethyl-3,12-epoxy-12H-pyrano[4,3-j]-1,2-benzodioxepin-10- ol 71939-50-9 ≥96% 284.35 C15H24O5 CC1CCC2C(C(OC3C24C1CCC(O3)(OO4)C)O)C Ambient Ambient Insoluble in water.   Soluble in acetone and ethanol. "Ontikatze T, Rudner J, Handrick R, et al. Dihydroartemisinin is a Hypoxia-Active Anti-Cancer Drug in Colorectal Carcinoma Cells. Front Oncol. 2014 May 19;4:116. PMID: 24904829.

 

Wanzira H, Kakuru A, Arinaitwe E, et al. Longitudinal Outcomes in a Cohort of Ugandan Children Randomized to Artemether-lumefantrine Versus Dihydroartemisinin-piperaquine for the Treatment of Malaria. Clin Infect Dis. 2014 May 13. [Epub ahead of print]. PMID: 24825870.

 

Li HJ, Xu FL, Wang YH, et al. Dihydroartemisinin: a new story of an old drug against Schistosoma mansoni infection. Parasitol Res. 2014 Jan;113(1):239-41. PMID: 24146209.

 

Flobinus A, Taudon N, Desbordes M, et al. Stability and antiviral activity against human cytomegalovirus of artemisinin derivatives. J Antimicrob Chemother. 2014 Jan;69(1):34-40. PMID: 24003183.

 

Odaka Y, Xu B, Luo Y, et al. Dihydroartemisinin inhibits the mammalian target of rapamycin-mediated signaling pathways in tumor cells. Carcinogenesis. 2014 Jan;35(1):192-200. PMID: 23929438.

 

Wei M, Xie X, Chu X, et al. Dihydroartemisinin suppresses ovalbumin-induced airway inflammation in a mouse allergic asthma model. Immunopharmacol Immunotoxicol. 2013 Jun;35(3):382-9. PMID: 23635079.

" None Not dangerous goods.

LKT A6982 Artesunate 50 mg 40.7 Sesquiterpene lactone derived from Artemesia. (3R,5aS,6R,8aS,9R,10S,12R,12aR)-Decahydro-3,6,9-trimethyl-3,12-epoxy-12H-pyrano[4,3-j]1,2-benzodioxepin-10-ol,hydrogen succinate Artesunic acid; Dihydroqinghaosu hemisuccinate; Arsumax; Plasmotrin; Qinghaozhi 88495-63-0 ≥98% 384.42 C19H28O8 CC1CCC2C(C(OC3C24C1CCC(O3)(OO4)C)OC(=O)CCC(=O)O)C Ambient Ambient Slightly soluble in water. "Zhang LX, Liu ZN, Ye J, et al. Artesunate exerts an anti-immunosuppressive effect on cervical cancer by inhibiting PGE2 production and Foxp3 expression. Cell Biol Int. 2014 May;38(5):639-46. PMID: 24446394.

 

Dong HY, Wang ZF. Antitumor effects of artesunate on human breast carcinoma MCF-7 cells and IGF-IR expression in nude mice xenografts. Chin J Cancer Res. 2014 Apr;26(2):200-7. PMID: 24826061.

 

Sharma BN, Marschall M, Henriksen S, et al. Antiviral effects of artesunate on polyomavirus BK replication in primary human kidney cells. Antimicrob Agents Chemother. 2014 Jan;58(1):279-89. PMID: 24145549.

 

Cheng R, Li C, Li C, et al. The artemisinin derivative artesunate inhibits corneal neovascularization by inducing ROS-dependent apoptosis in vascular endothelial cells. Invest Ophthalmol Vis Sci. 2013 May 15;54(5):3400-9. PMID: 23611999.

 

Gomes TC, de Andrade Júnior HF, Lescano SA, et al. In vitro action of antiparasitic drugs, especially artesunate, against Toxoplasma gondii. Rev Soc Bras Med Trop. 2012 Jul-Aug;45(4):485-90. PMID: 22930046.

 

Haynes RK, Chan WC, Wong HN, et al. Facile oxidation of leucomethylene blue and dihydroflavins by artemisinins: relationship with flavoenzyme function and antimalarial mechanism of action. ChemMedChem. 2010 Aug 2;5(8):1282-99. PMID: 20629071." Xn Not dangerous goods.

LKT A6982 Artesunate 100 mg 61.1 Sesquiterpene lactone derived from Artemesia. (3R,5aS,6R,8aS,9R,10S,12R,12aR)-Decahydro-3,6,9-trimethyl-3,12-epoxy-12H-pyrano[4,3-j]1,2-benzodioxepin-10-ol,hydrogen succinate Artesunic acid; Dihydroqinghaosu hemisuccinate; Arsumax; Plasmotrin; Qinghaozhi 88495-63-0 ≥98% 384.42 C19H28O8 CC1CCC2C(C(OC3C24C1CCC(O3)(OO4)C)OC(=O)CCC(=O)O)C Ambient Ambient Slightly soluble in water. "Zhang LX, Liu ZN, Ye J, et al. Artesunate exerts an anti-immunosuppressive effect on cervical cancer by inhibiting PGE2 production and Foxp3 expression. Cell Biol Int. 2014 May;38(5):639-46. PMID: 24446394.

 

Dong HY, Wang ZF. Antitumor effects of artesunate on human breast carcinoma MCF-7 cells and IGF-IR expression in nude mice xenografts. Chin J Cancer Res. 2014 Apr;26(2):200-7. PMID: 24826061.

 

Sharma BN, Marschall M, Henriksen S, et al. Antiviral effects of artesunate on polyomavirus BK replication in primary human kidney cells. Antimicrob Agents Chemother. 2014 Jan;58(1):279-89. PMID: 24145549.

 

Cheng R, Li C, Li C, et al. The artemisinin derivative artesunate inhibits corneal neovascularization by inducing ROS-dependent apoptosis in vascular endothelial cells. Invest Ophthalmol Vis Sci. 2013 May 15;54(5):3400-9. PMID: 23611999.

 

Gomes TC, de Andrade Júnior HF, Lescano SA, et al. In vitro action of antiparasitic drugs, especially artesunate, against Toxoplasma gondii. Rev Soc Bras Med Trop. 2012 Jul-Aug;45(4):485-90. PMID: 22930046.

 

Haynes RK, Chan WC, Wong HN, et al. Facile oxidation of leucomethylene blue and dihydroflavins by artemisinins: relationship with flavoenzyme function and antimalarial mechanism of action. ChemMedChem. 2010 Aug 2;5(8):1282-99. PMID: 20629071." Xn Not dangerous goods.

LKT A6982 Artesunate 500 mg 101.9 Sesquiterpene lactone derived from Artemesia. (3R,5aS,6R,8aS,9R,10S,12R,12aR)-Decahydro-3,6,9-trimethyl-3,12-epoxy-12H-pyrano[4,3-j]1,2-benzodioxepin-10-ol,hydrogen succinate Artesunic acid; Dihydroqinghaosu hemisuccinate; Arsumax; Plasmotrin; Qinghaozhi 88495-63-0 ≥98% 384.42 C19H28O8 CC1CCC2C(C(OC3C24C1CCC(O3)(OO4)C)OC(=O)CCC(=O)O)C Ambient Ambient Slightly soluble in water. "Zhang LX, Liu ZN, Ye J, et al. Artesunate exerts an anti-immunosuppressive effect on cervical cancer by inhibiting PGE2 production and Foxp3 expression. Cell Biol Int. 2014 May;38(5):639-46. PMID: 24446394.

 

Dong HY, Wang ZF. Antitumor effects of artesunate on human breast carcinoma MCF-7 cells and IGF-IR expression in nude mice xenografts. Chin J Cancer Res. 2014 Apr;26(2):200-7. PMID: 24826061.

 

Sharma BN, Marschall M, Henriksen S, et al. Antiviral effects of artesunate on polyomavirus BK replication in primary human kidney cells. Antimicrob Agents Chemother. 2014 Jan;58(1):279-89. PMID: 24145549.

 

Cheng R, Li C, Li C, et al. The artemisinin derivative artesunate inhibits corneal neovascularization by inducing ROS-dependent apoptosis in vascular endothelial cells. Invest Ophthalmol Vis Sci. 2013 May 15;54(5):3400-9. PMID: 23611999.

 

Gomes TC, de Andrade Júnior HF, Lescano SA, et al. In vitro action of antiparasitic drugs, especially artesunate, against Toxoplasma gondii. Rev Soc Bras Med Trop. 2012 Jul-Aug;45(4):485-90. PMID: 22930046.

 

Haynes RK, Chan WC, Wong HN, et al. Facile oxidation of leucomethylene blue and dihydroflavins by artemisinins: relationship with flavoenzyme function and antimalarial mechanism of action. ChemMedChem. 2010 Aug 2;5(8):1282-99. PMID: 20629071." Xn Not dangerous goods.

LKT A6982 Artesunate 1 g 149.5 Sesquiterpene lactone derived from Artemesia. (3R,5aS,6R,8aS,9R,10S,12R,12aR)-Decahydro-3,6,9-trimethyl-3,12-epoxy-12H-pyrano[4,3-j]1,2-benzodioxepin-10-ol,hydrogen succinate Artesunic acid; Dihydroqinghaosu hemisuccinate; Arsumax; Plasmotrin; Qinghaozhi 88495-63-0 ≥98% 384.42 C19H28O8 CC1CCC2C(C(OC3C24C1CCC(O3)(OO4)C)OC(=O)CCC(=O)O)C Ambient Ambient Slightly soluble in water. "Zhang LX, Liu ZN, Ye J, et al. Artesunate exerts an anti-immunosuppressive effect on cervical cancer by inhibiting PGE2 production and Foxp3 expression. Cell Biol Int. 2014 May;38(5):639-46. PMID: 24446394.

 

Dong HY, Wang ZF. Antitumor effects of artesunate on human breast carcinoma MCF-7 cells and IGF-IR expression in nude mice xenografts. Chin J Cancer Res. 2014 Apr;26(2):200-7. PMID: 24826061.

 

Sharma BN, Marschall M, Henriksen S, et al. Antiviral effects of artesunate on polyomavirus BK replication in primary human kidney cells. Antimicrob Agents Chemother. 2014 Jan;58(1):279-89. PMID: 24145549.

 

Cheng R, Li C, Li C, et al. The artemisinin derivative artesunate inhibits corneal neovascularization by inducing ROS-dependent apoptosis in vascular endothelial cells. Invest Ophthalmol Vis Sci. 2013 May 15;54(5):3400-9. PMID: 23611999.

 

Gomes TC, de Andrade Júnior HF, Lescano SA, et al. In vitro action of antiparasitic drugs, especially artesunate, against Toxoplasma gondii. Rev Soc Bras Med Trop. 2012 Jul-Aug;45(4):485-90. PMID: 22930046.

 

Haynes RK, Chan WC, Wong HN, et al. Facile oxidation of leucomethylene blue and dihydroflavins by artemisinins: relationship with flavoenzyme function and antimalarial mechanism of action. ChemMedChem. 2010 Aug 2;5(8):1282-99. PMID: 20629071." Xn Not dangerous goods.

LKT A7034 Aripiprazole 100 mg 65.6 D2 and 5-HT1A partial agonist, 5-HT2C/6/7 antagonist, SERT inhibitor. 7-[4-[4-(2,3-dichorophenyl)piperazin-1-yl]butoxy]-1, 2, 3, 4-tetrahydroquinolin-2-one 129722-12-9 ≥98% 448.39 C23H27Cl2N3O2 C1CC(=O)NC2=C1C=CC(=C2)OCCCCN3CCN(CC3)C4=C(C(=CC=C4)Cl)Cl Ambient Ambient "Lee JS, Lee JD, Park HJ, et al. Is the GABA System Related to the Social Competence Improvement Effect of Aripiprazole? An (18)F-Fluoroflumazenil PET Study. Psychiatry Investig. 2013 Mar;10(1):75-80. PMID: 23482902.

 

Miljević Č, Nikolić-Kokić A, Nikolić M, et al. Effect of atypical antipsychotics on antioxidant enzyme activities in human erythrocytes (in vitro study). Hum Psychopharmacol. 2013 Jan;28(1):1-6. PMID: 23124725.

 

Ishima T, Iyo M, Hashimoto K. Neurite outgrowth mediated by the heat shock protein Hsp90α: a novel target for the antipsychotic drug aripiprazole. Transl Psychiatry. 2012 Oct 16;2:e170. PMID: 23047241.

 

Zupancic M, Gonzalez ML. Aripiprazole in the acute and maintenance phase of bipolar I disorder. Ther Clin Risk Manag. 2012;8:1-6. PMID: 22298948.

 

Burda K, Czubak A, Kus K, et al. Influence of aripiprazole on the antidepressant, anxiolytic and cognitive functions of rats. Pharmacol Rep. 2011;63(4):898-907. PMID: 22001977.

 

Stark AD, Jordan S, Allers KA, et al. Interaction of the novel antipsychotic aripiprazole with 5-HT1A and 5-HT 2A receptors: functional receptor-binding and in vivo electrophysiological studies. Psychopharmacology (Berl). 2007 Feb;190(3):373-82. PMID: 17242925.

" Not dangerous goods.

LKT A7034 Aripiprazole 250 mg 121.9 D2 and 5-HT1A partial agonist, 5-HT2C/6/7 antagonist, SERT inhibitor. 7-[4-[4-(2,3-dichorophenyl)piperazin-1-yl]butoxy]-1, 2, 3, 4-tetrahydroquinolin-2-one 129722-12-9 ≥98% 448.39 C23H27Cl2N3O2 C1CC(=O)NC2=C1C=CC(=C2)OCCCCN3CCN(CC3)C4=C(C(=CC=C4)Cl)Cl Ambient Ambient "Lee JS, Lee JD, Park HJ, et al. Is the GABA System Related to the Social Competence Improvement Effect of Aripiprazole? An (18)F-Fluoroflumazenil PET Study. Psychiatry Investig. 2013 Mar;10(1):75-80. PMID: 23482902.

 

Miljević Č, Nikolić-Kokić A, Nikolić M, et al. Effect of atypical antipsychotics on antioxidant enzyme activities in human erythrocytes (in vitro study). Hum Psychopharmacol. 2013 Jan;28(1):1-6. PMID: 23124725.

 

Ishima T, Iyo M, Hashimoto K. Neurite outgrowth mediated by the heat shock protein Hsp90α: a novel target for the antipsychotic drug aripiprazole. Transl Psychiatry. 2012 Oct 16;2:e170. PMID: 23047241.

 

Zupancic M, Gonzalez ML. Aripiprazole in the acute and maintenance phase of bipolar I disorder. Ther Clin Risk Manag. 2012;8:1-6. PMID: 22298948.

 

Burda K, Czubak A, Kus K, et al. Influence of aripiprazole on the antidepressant, anxiolytic and cognitive functions of rats. Pharmacol Rep. 2011;63(4):898-907. PMID: 22001977.

 

Stark AD, Jordan S, Allers KA, et al. Interaction of the novel antipsychotic aripiprazole with 5-HT1A and 5-HT 2A receptors: functional receptor-binding and in vivo electrophysiological studies. Psychopharmacology (Berl). 2007 Feb;190(3):373-82. PMID: 17242925.

" Not dangerous goods.

LKT A7034 Aripiprazole 1 g 346.9 D2 and 5-HT1A partial agonist, 5-HT2C/6/7 antagonist, SERT inhibitor. 7-[4-[4-(2,3-dichorophenyl)piperazin-1-yl]butoxy]-1, 2, 3, 4-tetrahydroquinolin-2-one 129722-12-9 ≥98% 448.39 C23H27Cl2N3O2 C1CC(=O)NC2=C1C=CC(=C2)OCCCCN3CCN(CC3)C4=C(C(=CC=C4)Cl)Cl Ambient Ambient "Lee JS, Lee JD, Park HJ, et al. Is the GABA System Related to the Social Competence Improvement Effect of Aripiprazole? An (18)F-Fluoroflumazenil PET Study. Psychiatry Investig. 2013 Mar;10(1):75-80. PMID: 23482902.

 

Miljević Č, Nikolić-Kokić A, Nikolić M, et al. Effect of atypical antipsychotics on antioxidant enzyme activities in human erythrocytes (in vitro study). Hum Psychopharmacol. 2013 Jan;28(1):1-6. PMID: 23124725.

 

Ishima T, Iyo M, Hashimoto K. Neurite outgrowth mediated by the heat shock protein Hsp90α: a novel target for the antipsychotic drug aripiprazole. Transl Psychiatry. 2012 Oct 16;2:e170. PMID: 23047241.

 

Zupancic M, Gonzalez ML. Aripiprazole in the acute and maintenance phase of bipolar I disorder. Ther Clin Risk Manag. 2012;8:1-6. PMID: 22298948.

 

Burda K, Czubak A, Kus K, et al. Influence of aripiprazole on the antidepressant, anxiolytic and cognitive functions of rats. Pharmacol Rep. 2011;63(4):898-907. PMID: 22001977.

 

Stark AD, Jordan S, Allers KA, et al. Interaction of the novel antipsychotic aripiprazole with 5-HT1A and 5-HT 2A receptors: functional receptor-binding and in vivo electrophysiological studies. Psychopharmacology (Berl). 2007 Feb;190(3):373-82. PMID: 17242925.

" Not dangerous goods.

LKT A7071 Atriopeptin II, rat/rabbit/mouse 0.5 mg 300.1 ANP analog, cardiomodulatory peptide; NPR-A agonist. ≥95% 2386.67 C98H156N34O32S2 CCC(C)C1C(=O)NCC(=O)NC(C(=O)NC(C(=O)NC(C(=O)NCC(=O)NC(C(=O)NCC(=O)NC(CSSCC(C(=O)NC(C(=O)NCC(=O)NCC(=O)NC(C(=O)NC(C(=O)NC(C(=O)NC(C(=O)N1)CCCNC(=N)N)CC(=O)O)C(C)CC)CCCNC(=N)N)CC2=CC=CC=C2)NC(=O)C(CO)NC(=O)C(CO)N)C(=O)NC(CC(=O)N)C(=O)NC(CO)C(=O)NC(CC3=CC=CC=C3)C(=O)NC(CCCNC(=N)N)C(=O)O)CC(C)C)CO)CCC(=O)N)C Ambient -20°C "Ströhle A, Jahn H, Montkowski A, et al. Central and peripheral administration of atriopeptin is anxiolytic in rats. Neuroendocrinology. 1997 Mar;65(3):210-5. PMID: 9088002.

 

Prada JA, Ross R, Clark KE. Effect of atrial natriuretic peptide and other vasoactive compounds on the uterine vascular bed of the nonpregnant sheep. Proc Soc Exp Biol Med. 1992 Dec;201(3):261-6. PMID: 1438342.

"

LKT A7071 Atriopeptin II, rat/rabbit/mouse 1 mg 510 ANP analog, cardiomodulatory peptide; NPR-A agonist. ≥95% 2386.67 C98H156N34O32S2 CCC(C)C1C(=O)NCC(=O)NC(C(=O)NC(C(=O)NC(C(=O)NCC(=O)NC(C(=O)NCC(=O)NC(CSSCC(C(=O)NC(C(=O)NCC(=O)NCC(=O)NC(C(=O)NC(C(=O)NC(C(=O)NC(C(=O)N1)CCCNC(=N)N)CC(=O)O)C(C)CC)CCCNC(=N)N)CC2=CC=CC=C2)NC(=O)C(CO)NC(=O)C(CO)N)C(=O)NC(CC(=O)N)C(=O)NC(CO)C(=O)NC(CC3=CC=CC=C3)C(=O)NC(CCCNC(=N)N)C(=O)O)CC(C)C)CO)CCC(=O)N)C Ambient -20°C "Ströhle A, Jahn H, Montkowski A, et al. Central and peripheral administration of atriopeptin is anxiolytic in rats. Neuroendocrinology. 1997 Mar;65(3):210-5. PMID: 9088002.

 

Prada JA, Ross R, Clark KE. Effect of atrial natriuretic peptide and other vasoactive compounds on the uterine vascular bed of the nonpregnant sheep. Proc Soc Exp Biol Med. 1992 Dec;201(3):261-6. PMID: 1438342.

"

LKT A7071 Atriopeptin II, rat/rabbit/mouse 2.5 mg 900.1 ANP analog, cardiomodulatory peptide; NPR-A agonist. ≥95% 2386.67 C98H156N34O32S2 CCC(C)C1C(=O)NCC(=O)NC(C(=O)NC(C(=O)NC(C(=O)NCC(=O)NC(C(=O)NCC(=O)NC(CSSCC(C(=O)NC(C(=O)NCC(=O)NCC(=O)NC(C(=O)NC(C(=O)NC(C(=O)NC(C(=O)N1)CCCNC(=N)N)CC(=O)O)C(C)CC)CCCNC(=N)N)CC2=CC=CC=C2)NC(=O)C(CO)NC(=O)C(CO)N)C(=O)NC(CC(=O)N)C(=O)NC(CO)C(=O)NC(CC3=CC=CC=C3)C(=O)NC(CCCNC(=N)N)C(=O)O)CC(C)C)CO)CCC(=O)N)C Ambient -20°C "Ströhle A, Jahn H, Montkowski A, et al. Central and peripheral administration of atriopeptin is anxiolytic in rats. Neuroendocrinology. 1997 Mar;65(3):210-5. PMID: 9088002.

 

Prada JA, Ross R, Clark KE. Effect of atrial natriuretic peptide and other vasoactive compounds on the uterine vascular bed of the nonpregnant sheep. Proc Soc Exp Biol Med. 1992 Dec;201(3):261-6. PMID: 1438342.

"

LKT A7072 Atriopeptin III 0.5 mg 276.2 ANP analog, cardiomodulatory peptide; NPR-A agonist. ≥95% 2549.85 C107H165N35O34S2 Ambient -20°C "Wang J, Shi P. Structure-function interrelation and clinical effect of atrial natriuretic peptide (ANP). Chin Med J (Engl). 1995 Apr;108(4):255-8. PMID: 7789210.

 

Lanese DM, Yuan BH, Falk SA, et al. Effects of atriopeptin III on isolated rat afferent and efferent arterioles. Am J Physiol. 1991 Dec;261(6 Pt 2):F1102-9. PMID: 1661082.

" Not dangerous goods.

LKT A7072 Atriopeptin III 1 mg 468.2 ANP analog, cardiomodulatory peptide; NPR-A agonist. ≥95% 2549.85 C107H165N35O34S2 Ambient -20°C "Wang J, Shi P. Structure-function interrelation and clinical effect of atrial natriuretic peptide (ANP). Chin Med J (Engl). 1995 Apr;108(4):255-8. PMID: 7789210.

 

Lanese DM, Yuan BH, Falk SA, et al. Effects of atriopeptin III on isolated rat afferent and efferent arterioles. Am J Physiol. 1991 Dec;261(6 Pt 2):F1102-9. PMID: 1661082.

" Not dangerous goods.

LKT A7072 Atriopeptin III 2.5 mg 828.1 ANP analog, cardiomodulatory peptide; NPR-A agonist. ≥95% 2549.85 C107H165N35O34S2 Ambient -20°C "Wang J, Shi P. Structure-function interrelation and clinical effect of atrial natriuretic peptide (ANP). Chin Med J (Engl). 1995 Apr;108(4):255-8. PMID: 7789210.

 

Lanese DM, Yuan BH, Falk SA, et al. Effects of atriopeptin III on isolated rat afferent and efferent arterioles. Am J Physiol. 1991 Dec;261(6 Pt 2):F1102-9. PMID: 1661082.

" Not dangerous goods.

LKT A7085 Arvanil 5 mg 85 CB1 agonist, TRPV1 agonist. "5,8,11,14-Eicosatetraenamide, N-((4-hydroxy-3-

methoxyphenyl)methyl)-, (all-Z)- 

" "N-((4-Hydroxy-3-methoxyphenyl)methyl)-5,8,11,14-

eicosatetraenamide (all-Z)-" 128007-31-8 ≥98% 439.63 C28H41NO3 CCCCCC=CCC=CCC=CCC=CCCCC(=O)NCC1=CC(=C(C=C1)O)OC Ambient Ambient Soluble in DMSO, DMF or ethanol. "Hayase T. Differential effects of TRPV1 receptor ligands against nicotine-induced depression-like behaviors. BMC Pharmacol. 2011 Jul 18;11:6. PMID: 21767384.

 

Kopczyńska B. Midcervical vagotomy precludes respiratory response to novel anti-inflammatory and anti-tumour drug arvanil in rats. Eur J Pharmacol. 2010 Sep 15;643(1):101-6. PMID: 20599930.

 

Sharkey KA, Cristino L, Oland LD, et al. Arvanil, anandamide and N-arachidonoyl-dopamine (NADA) inhibit emesis through cannabinoid CB1 and vanilloid TRPV1 receptors in the ferret. Eur J Neurosci. 2007 May;25(9):2773-82. PMID: 17459108.

 

Malfitano AM, Matarese G, Pisanti S, et al. Arvanil inhibits T lymphocyte activation and ameliorates autoimmune encephalomyelitis. J Neuroimmunol. 2006 Feb;171(1-2):110-9. PMID: 16239036.

 

Di Marzo V, Melck D, De Petrocellis L, et al. Cannabimimetic fatty acid derivatives in cancer and inflammation. Prostaglandins Other Lipid Mediat. 2000 Apr;61(1-2):43-61. PMID: 10785541.

" Not dangerous goods.

LKT A7208 Ascomycin 1 mg 50.6 FK506 analog; calcineurin inhibitor. 104987-12-4 ≥98% 792.01 C43H69NO12 CCC1C=C(CC(CC(C2C(CC(C(O2)(C(=O)C(=O)N3CCCCC3C(=O)OC(C(C(CC1=O)O)C)C(=CC4CCC(C(C4)OC)O)C)O)C)OC)OC)C)C Ambient 4°C Soluble in DMSO "Liu F, Wang YQ, Meng L, et al. FK506-binding protein 12 ligands: a patent review. Expert Opin Ther Pat. 2013 Nov;23(11):1435-49. PMID: 23957229.

 

Sierra-Paredes G, Sierra-Marcuño G. Ascomycin and FK506: pharmacology and therapeutic potential as anticonvulsants and neuroprotectants. CNS Neurosci Ther. 2008 Spring;14(1):36-46. PMID: 18482098.

 

Pahl A, Keller U. FK-506-binding proteins from streptomycetes producing immunosuppressive macrolactones of the FK-506 type. J Bacteriol. 1992 Sep;174(18):5888-94. PMID: 1381710." Xn Not dangerous goods.

LKT A7208 Ascomycin 5 mg 95.6 FK506 analog; calcineurin inhibitor. 104987-12-4 ≥98% 792.01 C43H69NO12 CCC1C=C(CC(CC(C2C(CC(C(O2)(C(=O)C(=O)N3CCCCC3C(=O)OC(C(C(CC1=O)O)C)C(=CC4CCC(C(C4)OC)O)C)O)C)OC)OC)C)C Ambient 4°C Soluble in DMSO "Liu F, Wang YQ, Meng L, et al. FK506-binding protein 12 ligands: a patent review. Expert Opin Ther Pat. 2013 Nov;23(11):1435-49. PMID: 23957229.

 

Sierra-Paredes G, Sierra-Marcuño G. Ascomycin and FK506: pharmacology and therapeutic potential as anticonvulsants and neuroprotectants. CNS Neurosci Ther. 2008 Spring;14(1):36-46. PMID: 18482098.

 

Pahl A, Keller U. FK-506-binding proteins from streptomycetes producing immunosuppressive macrolactones of the FK-506 type. J Bacteriol. 1992 Sep;174(18):5888-94. PMID: 1381710." Xn Not dangerous goods.

LKT A7210 L-(+)-Ascorbic Acid 100 g 65.6 Form of vitamin C found in various plant and food sources. Ascorbic acid; ; Vitamin C; Cantan; Cecon; Celin; Cevalin; Cewin; Hybrin; Lemascorb; Ribena; Vitacin 50-81-7 ≥98% 176.12 C6H8O6 C(C(C1C(=C(C(=O)O1)O)O)O)O Ambient Ambient Soluble in water (330 mg/mL), ethanol (25 mg/mL). Insoluble in ether, chloroform, benzene, or oils. "Amaya I, Osorio S, Martinez-Ferri E, et al. Increased antioxidant capacity in tomato by ectopic expression of the strawberry D-galacturonate reductase gene. Biotechnol J. 2014 Aug 21. [Epub ahead of print]. PMID: 25143316.

 

Kotchey GP, Gaugler JA, Kapralov AA, et al. Effect of antioxidants on enzyme-catalysed biodegradation of carbon nanotubes. J Mater Chem B Mater Biol Med. 2013;1(3):302-309. PMID: 23626907.

 

Crescini E, Gualandi L, Uberti D, et al. Ascorbic acid rescues cardiomyocyte development in Fgfr1(-/-) murine embryonic stem cells. Biochim Biophys Acta. 2013 Jan;1833(1):140-7. PMID: 22735182.

" Xn, Xi Not dangerous goods.

LKT A7210 L-(+)-Ascorbic Acid 500 g 168.7 Form of vitamin C found in various plant and food sources. Ascorbic acid; ; Vitamin C; Cantan; Cecon; Celin; Cevalin; Cewin; Hybrin; Lemascorb; Ribena; Vitacin 50-81-7 ≥98% 176.12 C6H8O6 C(C(C1C(=C(C(=O)O1)O)O)O)O Ambient Ambient Soluble in water (330 mg/mL), ethanol (25 mg/mL). Insoluble in ether, chloroform, benzene, or oils. "Amaya I, Osorio S, Martinez-Ferri E, et al. Increased antioxidant capacity in tomato by ectopic expression of the strawberry D-galacturonate reductase gene. Biotechnol J. 2014 Aug 21. [Epub ahead of print]. PMID: 25143316.

 

Kotchey GP, Gaugler JA, Kapralov AA, et al. Effect of antioxidants on enzyme-catalysed biodegradation of carbon nanotubes. J Mater Chem B Mater Biol Med. 2013;1(3):302-309. PMID: 23626907.

 

Crescini E, Gualandi L, Uberti D, et al. Ascorbic acid rescues cardiomyocyte development in Fgfr1(-/-) murine embryonic stem cells. Biochim Biophys Acta. 2013 Jan;1833(1):140-7. PMID: 22735182.

" Xn, Xi Not dangerous goods.

LKT A7332 Asiatic Acid, 95% 100 mg 47.6 Triterpene aglycone originally found in Centella. NSC 166063 464-92-6 ≥95% 488.7 C30H48O5 CC1CCC2(CCC3(C(=CCC4C3(CCC5C4(CC(C(C5(C)CO)O)O)C)C)C2C1C)C)C(=O)O Ambient Ambient Ethanol 10 mg/mL, DMSO 20 mg/mL, DMF 20 mg/mL "Si L, Xu J, Yi C, et al. Asiatic acid attenuates cardiac hypertrophy by blocking transforming growth factor-β1-mediated hypertrophic signaling in vitro and in vivo. Int J Mol Med. 2014 Aug;34(2):499-506. PMID: 24827470.

 

Yan SL, Yang HT, Lee YJ, et al. Asiatic acid ameliorates hepatic lipid accumulation and insulin resistance in mice consuming a high-fat diet. J Agric Food Chem. 2014 May 21;62(20):4625-31. PMID: 24779966.

 

Bunbupha S, Pakdeechote P, Kukongviriyapan U, et al. Asiatic Acid Reduces Blood Pressure by Enhancing Nitric Oxide Bioavailability with Modulation of eNOS and p47 phox Expression in l-NAME-induced Hypertensive Rats. Phytother Res. 2014 Apr 11. [Epub ahead of print]. PMID: 24723332.

 

Li ZW, Piao CD, Sun HH, et al. Asiatic acid inhibits adipogenic differentiation of bone marrow stromal cells. Cell Biochem Biophys. 2014 Mar;68(2):437-42. PMID: 23934183.

 

Zhang J, Ai L, Lv T, et al. Asiatic acid, a triterpene, inhibits cell proliferation through regulating the expression of focal adhesion kinase in multiple myeloma cells. Oncol Lett. 2013 Dec;6(6):1762-1766. PMID: 24260073.

 

Bian D, Zhang J, Wu X, et al. Asiatic acid isolated from Centella asiatica inhibits TGF-β1-induced collagen expression in human keloid fibroblasts via PPAR-γ activation. Int J Biol Sci. 2013 Oct 25;9(10):1032-42. PMID: 24250248.

 

Xu C, Wang W, Xu M, et al. Asiatic acid ameliorates tubulointerstitial fibrosis in mice with ureteral obstruction. Exp Ther Med. 2013 Sep;6(3):731-736. PMID: 24137256.

" None Not dangerous goods.

LKT A7332 Asiatic Acid, 95% 500 mg 163.2 Triterpene aglycone originally found in Centella. NSC 166063 464-92-6 ≥95% 488.7 C30H48O5 CC1CCC2(CCC3(C(=CCC4C3(CCC5C4(CC(C(C5(C)CO)O)O)C)C)C2C1C)C)C(=O)O Ambient Ambient Ethanol 10 mg/mL, DMSO 20 mg/mL, DMF 20 mg/mL "Si L, Xu J, Yi C, et al. Asiatic acid attenuates cardiac hypertrophy by blocking transforming growth factor-β1-mediated hypertrophic signaling in vitro and in vivo. Int J Mol Med. 2014 Aug;34(2):499-506. PMID: 24827470.

 

Yan SL, Yang HT, Lee YJ, et al. Asiatic acid ameliorates hepatic lipid accumulation and insulin resistance in mice consuming a high-fat diet. J Agric Food Chem. 2014 May 21;62(20):4625-31. PMID: 24779966.

 

Bunbupha S, Pakdeechote P, Kukongviriyapan U, et al. Asiatic Acid Reduces Blood Pressure by Enhancing Nitric Oxide Bioavailability with Modulation of eNOS and p47 phox Expression in l-NAME-induced Hypertensive Rats. Phytother Res. 2014 Apr 11. [Epub ahead of print]. PMID: 24723332.

 

Li ZW, Piao CD, Sun HH, et al. Asiatic acid inhibits adipogenic differentiation of bone marrow stromal cells. Cell Biochem Biophys. 2014 Mar;68(2):437-42. PMID: 23934183.

 

Zhang J, Ai L, Lv T, et al. Asiatic acid, a triterpene, inhibits cell proliferation through regulating the expression of focal adhesion kinase in multiple myeloma cells. Oncol Lett. 2013 Dec;6(6):1762-1766. PMID: 24260073.

 

Bian D, Zhang J, Wu X, et al. Asiatic acid isolated from Centella asiatica inhibits TGF-β1-induced collagen expression in human keloid fibroblasts via PPAR-γ activation. Int J Biol Sci. 2013 Oct 25;9(10):1032-42. PMID: 24250248.

 

Xu C, Wang W, Xu M, et al. Asiatic acid ameliorates tubulointerstitial fibrosis in mice with ureteral obstruction. Exp Ther Med. 2013 Sep;6(3):731-736. PMID: 24137256.

" None Not dangerous goods.

LKT A7333 Asiaticoside 1 mg 29.9 Triterpene found in Centella, prevents melanogenesis. (2α,3β,4α)-2,3,23-Trihydroxyurs-12-en-28-oic acid O-6-deoxy-a-L-mannopyranosyl-(1->4)-O-β-D-glucopyranosyl-(1->6)-O-β-D-glucopyranosyl ester 16830-15-2 ≥90% 959.12 C48H78O19 CC1CCC2(CCC3(C(=CCC4C3(CCC5C4(CC(C(C5(C)CO)O)O)C)C)C2C1C)C)C(=O)OC6C(C(C(C(O6)COC7C(C(C(C(O7)CO)OC8C(C(C(C(O8)C)O)O)O)O)O)O)O)O Ambient 4°C Soluble in propylene glycol or ethanol. "Kwon KJ, Bae S, Kim K, et al. Asiaticoside, a component of Centella asiatica, inhibits melanogenesis in B16F10 mouse melanoma. Mol Med Rep. 2014 Jul;10(1):503-7. PMID: 24756377.

 

Chen S, Yin ZJ, Jiang C, et al. Asiaticoside attenuates memory impairment induced by transient cerebral ischemia-reperfusion in mice through anti-inflammatory mechanism. Pharmacol Biochem Behav. 2014 Jul;122:7-15. PMID: 24631487.

 

Al-Saeedi FJ. Study of the cytotoxicity of asiaticoside on rats and tumour cells. BMC Cancer. 2014 Mar 25;14:220. PMID: 24667059.

 

Wan J, Gong X, Jiang R, et al. Antipyretic and anti-inflammatory effects of asiaticoside in lipopolysaccharide-treated rat through up-regulation of heme oxygenase-1. Phytother Res. 2013 Aug;27(8):1136-42. PMID: 22972613.

 

Lee JH, Kim HL, Lee MH, et al. Asiaticoside enhances normal human skin cell migration, attachment and growth in vitro wound healing model. Phytomedicine. 2012 Oct 15;19(13):1223-7. PMID: 22939261.

" None Not dangerous goods.

LKT A7333 Asiaticoside 5 mg 122.3 Triterpene found in Centella, prevents melanogenesis. (2α,3β,4α)-2,3,23-Trihydroxyurs-12-en-28-oic acid O-6-deoxy-a-L-mannopyranosyl-(1->4)-O-β-D-glucopyranosyl-(1->6)-O-β-D-glucopyranosyl ester 16830-15-2 ≥90% 959.12 C48H78O19 CC1CCC2(CCC3(C(=CCC4C3(CCC5C4(CC(C(C5(C)CO)O)O)C)C)C2C1C)C)C(=O)OC6C(C(C(C(O6)COC7C(C(C(C(O7)CO)OC8C(C(C(C(O8)C)O)O)O)O)O)O)O)O Ambient 4°C Soluble in propylene glycol or ethanol. "Kwon KJ, Bae S, Kim K, et al. Asiaticoside, a component of Centella asiatica, inhibits melanogenesis in B16F10 mouse melanoma. Mol Med Rep. 2014 Jul;10(1):503-7. PMID: 24756377.

 

Chen S, Yin ZJ, Jiang C, et al. Asiaticoside attenuates memory impairment induced by transient cerebral ischemia-reperfusion in mice through anti-inflammatory mechanism. Pharmacol Biochem Behav. 2014 Jul;122:7-15. PMID: 24631487.

 

Al-Saeedi FJ. Study of the cytotoxicity of asiaticoside on rats and tumour cells. BMC Cancer. 2014 Mar 25;14:220. PMID: 24667059.

 

Wan J, Gong X, Jiang R, et al. Antipyretic and anti-inflammatory effects of asiaticoside in lipopolysaccharide-treated rat through up-regulation of heme oxygenase-1. Phytother Res. 2013 Aug;27(8):1136-42. PMID: 22972613.

 

Lee JH, Kim HL, Lee MH, et al. Asiaticoside enhances normal human skin cell migration, attachment and growth in vitro wound healing model. Phytomedicine. 2012 Oct 15;19(13):1223-7. PMID: 22939261.

" None Not dangerous goods.

LKT A7333 Asiaticoside 10 mg 163.2 Triterpene found in Centella, prevents melanogenesis. (2α,3β,4α)-2,3,23-Trihydroxyurs-12-en-28-oic acid O-6-deoxy-a-L-mannopyranosyl-(1->4)-O-β-D-glucopyranosyl-(1->6)-O-β-D-glucopyranosyl ester 16830-15-2 ≥90% 959.12 C48H78O19 CC1CCC2(CCC3(C(=CCC4C3(CCC5C4(CC(C(C5(C)CO)O)O)C)C)C2C1C)C)C(=O)OC6C(C(C(C(O6)COC7C(C(C(C(O7)CO)OC8C(C(C(C(O8)C)O)O)O)O)O)O)O)O Ambient 4°C Soluble in propylene glycol or ethanol. "Kwon KJ, Bae S, Kim K, et al. Asiaticoside, a component of Centella asiatica, inhibits melanogenesis in B16F10 mouse melanoma. Mol Med Rep. 2014 Jul;10(1):503-7. PMID: 24756377.

 

Chen S, Yin ZJ, Jiang C, et al. Asiaticoside attenuates memory impairment induced by transient cerebral ischemia-reperfusion in mice through anti-inflammatory mechanism. Pharmacol Biochem Behav. 2014 Jul;122:7-15. PMID: 24631487.

 

Al-Saeedi FJ. Study of the cytotoxicity of asiaticoside on rats and tumour cells. BMC Cancer. 2014 Mar 25;14:220. PMID: 24667059.

 

Wan J, Gong X, Jiang R, et al. Antipyretic and anti-inflammatory effects of asiaticoside in lipopolysaccharide-treated rat through up-regulation of heme oxygenase-1. Phytother Res. 2013 Aug;27(8):1136-42. PMID: 22972613.

 

Lee JH, Kim HL, Lee MH, et al. Asiaticoside enhances normal human skin cell migration, attachment and growth in vitro wound healing model. Phytomedicine. 2012 Oct 15;19(13):1223-7. PMID: 22939261.

" None Not dangerous goods.

LKT A7462 Aspartame 5 g 127.1 Dipeptide ester, commercial sweetener. N-L-α-Aspartyl-L-phenylalanine 1-methyl ester APM; Equal; NutraSweet; Sanecta 22839-47-0 ≥98% 294.3 C14H18N2O5 COC(=O)C(CC1=CC=CC=C1)NC(=O)C(CC(=O)O)N Ambient Ambient Slightly soluble in water. "Prashant GM, Patil RB, Nagaraj T, et al. The antimicrobial activity of the three commercially available intense sweeteners against common periodontal pathogens: an in vitro study. J Contemp Dent Pract. 2012 Nov 1;13(6):749-52. PMID: 23403996.

 

Rani S, Gupta MC. Evaluation and comparison of antinociceptive activity of aspartame with sucrose. Pharmacol Rep. 2012;64(2):293-8. PMID: 22661178.

 

Yagasaki M, Hashimoto S. Synthesis and application of dipeptides; current status and perspectives. Appl Microbiol Biotechnol. 2008 Nov;81(1):13-22. PMID: 18795289.

 

Butchko HH, Stargel WW, Comer CP, et al. Aspartame: review of safety. Regul Toxicol Pharmacol. 2002 Apr;35(2 Pt 2):S1-93. PMID: 12180494.

" None Not dangerous goods.

LKT A7462 Aspartame 25 g 508.3 Dipeptide ester, commercial sweetener. N-L-α-Aspartyl-L-phenylalanine 1-methyl ester APM; Equal; NutraSweet; Sanecta 22839-47-0 ≥98% 294.3 C14H18N2O5 COC(=O)C(CC1=CC=CC=C1)NC(=O)C(CC(=O)O)N Ambient Ambient Slightly soluble in water. "Prashant GM, Patil RB, Nagaraj T, et al. The antimicrobial activity of the three commercially available intense sweeteners against common periodontal pathogens: an in vitro study. J Contemp Dent Pract. 2012 Nov 1;13(6):749-52. PMID: 23403996.

 

Rani S, Gupta MC. Evaluation and comparison of antinociceptive activity of aspartame with sucrose. Pharmacol Rep. 2012;64(2):293-8. PMID: 22661178.

 

Yagasaki M, Hashimoto S. Synthesis and application of dipeptides; current status and perspectives. Appl Microbiol Biotechnol. 2008 Nov;81(1):13-22. PMID: 18795289.

 

Butchko HH, Stargel WW, Comer CP, et al. Aspartame: review of safety. Regul Toxicol Pharmacol. 2002 Apr;35(2 Pt 2):S1-93. PMID: 12180494.

" None Not dangerous goods.

LKT A7462 Aspartame 1 g 51.1 Dipeptide ester, commercial sweetener. N-L-α-Aspartyl-L-phenylalanine 1-methyl ester APM; Equal; NutraSweet; Sanecta 22839-47-0 ≥98% 294.3 C14H18N2O5 COC(=O)C(CC1=CC=CC=C1)NC(=O)C(CC(=O)O)N Ambient Ambient Slightly soluble in water. "Prashant GM, Patil RB, Nagaraj T, et al. The antimicrobial activity of the three commercially available intense sweeteners against common periodontal pathogens: an in vitro study. J Contemp Dent Pract. 2012 Nov 1;13(6):749-52. PMID: 23403996.

 

Rani S, Gupta MC. Evaluation and comparison of antinociceptive activity of aspartame with sucrose. Pharmacol Rep. 2012;64(2):293-8. PMID: 22661178.

 

Yagasaki M, Hashimoto S. Synthesis and application of dipeptides; current status and perspectives. Appl Microbiol Biotechnol. 2008 Nov;81(1):13-22. PMID: 18795289.

 

Butchko HH, Stargel WW, Comer CP, et al. Aspartame: review of safety. Regul Toxicol Pharmacol. 2002 Apr;35(2 Pt 2):S1-93. PMID: 12180494.

" None Not dangerous goods.

LKT A7578 Astragaloside IV 10 mg 167.4 Found in Astragalus membranaceus. 83207-58-3 ≥98% 784.97 C41H68O14 CC1(C(CCC23C1C(CC4C2(C3)CCC5(C4(CC(C5C6(CCC(O6)C(C)(C)O)C)O)C)C)OC7C(C(C(C(O7)CO)O)O)O)OC8C(C(C(CO8)O)O)O)C Ambient Ambient Soluble in DMSO (10 mg/mL), ethanol.  Insoluble in water. "Lu M, Wang H, Wang J, et al. Astragaloside IV Protects against Cardiac Hypertrophy via Inhibiting the Ca2+/CaN Signaling Pathway. Planta Med. 2013 Dec 11. [Epub ahead of print]. PMID: 24338553.

 

Wang SG, Xu Y, Chen JD, et al. Astragaloside IV stimulates angiogenesis and increases nitric oxide accumulation via JAK2/STAT3 and ERK1/2 pathway. Molecules. 2013 Oct 16;18(10):12809-19. PMID: 24135938.

 

He Y, Du M, Gao Y, et al. Astragaloside IV attenuates experimental autoimmune encephalomyelitis of mice by counteracting oxidative stress at multiple levels. PLoS One. 2013 Oct 4;8(10):e76495. PMID: 24124567.

 

Li M, Ma RN, Li LH, et al. Astragaloside IV reduces cerebral edema post-ischemia/reperfusion correlating the suppression of MMP-9 and AQP4. Eur J Pharmacol. 2013 Sep 5;715(1-3):189-95. PMID: 23747593.

 

Tu L, Pan CS, Wei XH, et al. Astragaloside IV protects heart from ischemia and reperfusion injury via energy regulation mechanism. Microcirculation. 2013 Jun 28. [Epub ahead of print]. PMID: 23809007.

" Not dangerous goods.

LKT A7578 Astragaloside IV 25 mg 335 Found in Astragalus membranaceus. 83207-58-3 ≥98% 784.97 C41H68O14 CC1(C(CCC23C1C(CC4C2(C3)CCC5(C4(CC(C5C6(CCC(O6)C(C)(C)O)C)O)C)C)OC7C(C(C(C(O7)CO)O)O)O)OC8C(C(C(CO8)O)O)O)C Ambient Ambient Soluble in DMSO (10 mg/mL), ethanol.  Insoluble in water. "Lu M, Wang H, Wang J, et al. Astragaloside IV Protects against Cardiac Hypertrophy via Inhibiting the Ca2+/CaN Signaling Pathway. Planta Med. 2013 Dec 11. [Epub ahead of print]. PMID: 24338553.

 

Wang SG, Xu Y, Chen JD, et al. Astragaloside IV stimulates angiogenesis and increases nitric oxide accumulation via JAK2/STAT3 and ERK1/2 pathway. Molecules. 2013 Oct 16;18(10):12809-19. PMID: 24135938.

 

He Y, Du M, Gao Y, et al. Astragaloside IV attenuates experimental autoimmune encephalomyelitis of mice by counteracting oxidative stress at multiple levels. PLoS One. 2013 Oct 4;8(10):e76495. PMID: 24124567.

 

Li M, Ma RN, Li LH, et al. Astragaloside IV reduces cerebral edema post-ischemia/reperfusion correlating the suppression of MMP-9 and AQP4. Eur J Pharmacol. 2013 Sep 5;715(1-3):189-95. PMID: 23747593.

 

Tu L, Pan CS, Wei XH, et al. Astragaloside IV protects heart from ischemia and reperfusion injury via energy regulation mechanism. Microcirculation. 2013 Jun 28. [Epub ahead of print]. PMID: 23809007.

" Not dangerous goods.

LKT A7578 Astragaloside IV 100 mg 1004.5 Found in Astragalus membranaceus. 83207-58-3 ≥98% 784.97 C41H68O14 CC1(C(CCC23C1C(CC4C2(C3)CCC5(C4(CC(C5C6(CCC(O6)C(C)(C)O)C)O)C)C)OC7C(C(C(C(O7)CO)O)O)O)OC8C(C(C(CO8)O)O)O)C Ambient Ambient Soluble in DMSO (10 mg/mL), ethanol.  Insoluble in water. "Lu M, Wang H, Wang J, et al. Astragaloside IV Protects against Cardiac Hypertrophy via Inhibiting the Ca2+/CaN Signaling Pathway. Planta Med. 2013 Dec 11. [Epub ahead of print]. PMID: 24338553.

 

Wang SG, Xu Y, Chen JD, et al. Astragaloside IV stimulates angiogenesis and increases nitric oxide accumulation via JAK2/STAT3 and ERK1/2 pathway. Molecules. 2013 Oct 16;18(10):12809-19. PMID: 24135938.

 

He Y, Du M, Gao Y, et al. Astragaloside IV attenuates experimental autoimmune encephalomyelitis of mice by counteracting oxidative stress at multiple levels. PLoS One. 2013 Oct 4;8(10):e76495. PMID: 24124567.

 

Li M, Ma RN, Li LH, et al. Astragaloside IV reduces cerebral edema post-ischemia/reperfusion correlating the suppression of MMP-9 and AQP4. Eur J Pharmacol. 2013 Sep 5;715(1-3):189-95. PMID: 23747593.

 

Tu L, Pan CS, Wei XH, et al. Astragaloside IV protects heart from ischemia and reperfusion injury via energy regulation mechanism. Microcirculation. 2013 Jun 28. [Epub ahead of print]. PMID: 23809007.

" Not dangerous goods.

LKT A7618 Atenolol 1 g 71.2 β1-adrenergic antagonist. 4-[2-Hydroxy-3-[(1-methylethyl)amino]propoxy]benzeneacetamide Atehexal; Atenol; Cuxanorm; Ibinolo; Myocord; Prenormine; Tenoblock; Uniloc 29122-68-7 ≥98% 266.34 C14H22N2O3 CC(C)NCC(COC1=CC=C(C=C1)CC(=O)N)O Ambient Ambient Soluble in acetic acid and DMSO. Slightly soluble in water and isopropanol. Practically insoluble in acetonitrile, ethylacetate and chloroform. "Cockcroft JR, Pedersen ME. β-blockade: benefits beyond blood pressure reduction? J Clin Hypertens (Greenwich). 2012 Feb;14(2):112-20. PMID: 22277144.

 

Thadani U. Beta blockers in hypertension. Am J Cardiol. 1983 Nov 10;52(9):10D-15D. PMID: 6139008.

" None Not dangerous goods.

LKT A7618 Atenolol 5 g 142.4 β1-adrenergic antagonist. 4-[2-Hydroxy-3-[(1-methylethyl)amino]propoxy]benzeneacetamide Atehexal; Atenol; Cuxanorm; Ibinolo; Myocord; Prenormine; Tenoblock; Uniloc 29122-68-7 ≥98% 266.34 C14H22N2O3 CC(C)NCC(COC1=CC=C(C=C1)CC(=O)N)O Ambient Ambient Soluble in acetic acid and DMSO. Slightly soluble in water and isopropanol. Practically insoluble in acetonitrile, ethylacetate and chloroform. "Cockcroft JR, Pedersen ME. β-blockade: benefits beyond blood pressure reduction? J Clin Hypertens (Greenwich). 2012 Feb;14(2):112-20. PMID: 22277144.

 

Thadani U. Beta blockers in hypertension. Am J Cardiol. 1983 Nov 10;52(9):10D-15D. PMID: 6139008.

" None Not dangerous goods.

LKT A7618 Atenolol 25 g 453 β1-adrenergic antagonist. 4-[2-Hydroxy-3-[(1-methylethyl)amino]propoxy]benzeneacetamide Atehexal; Atenol; Cuxanorm; Ibinolo; Myocord; Prenormine; Tenoblock; Uniloc 29122-68-7 ≥98% 266.34 C14H22N2O3 CC(C)NCC(COC1=CC=C(C=C1)CC(=O)N)O Ambient Ambient Soluble in acetic acid and DMSO. Slightly soluble in water and isopropanol. Practically insoluble in acetonitrile, ethylacetate and chloroform. "Cockcroft JR, Pedersen ME. β-blockade: benefits beyond blood pressure reduction? J Clin Hypertens (Greenwich). 2012 Feb;14(2):112-20. PMID: 22277144.

 

Thadani U. Beta blockers in hypertension. Am J Cardiol. 1983 Nov 10;52(9):10D-15D. PMID: 6139008.

" None Not dangerous goods.

LKT A7656 Atomoxetine Hydrochloride 25 mg 159.4 NET and SERT inhibitor, NMDA antagonist. Strattera, tomoxetine, attentin 82248-59-7 ≥98% 291.82 C17H21NO HCl CC1=CC=CC=C1OC(CCNC)C2=CC=CC=C2.Cl Ambient Ambient Soluble in water (27.8mg/mL). DMSO 58 mg/mL. Ethanol 37 mg/mL. Chloroform, methanol. "Isaksson J, Hogmark A, Nilsson KW, et al. Effects of stimulants and atomoxetine on cortisol levels in children with ADHD. Psychiatry Res. 2013 Jul 11. pii: S0165-1781 PMID: 23850434.

 

Ercan ES, Akyol Ardic U, Kabukcu Basay B, et al. Atomoxetine response in the inattentive and combined subtypes of attention deficit hyperactivity disorder: a retrospective chart review. Atten Defic Hyperact Disord. 2013 Jun 5. [Epub ahead of print]. PMID: 23737214.

 

Silverstone PH, Dadashova R. Atomoxetine treatment for nicotine withdrawal: a pilot double-blind, placebo-controlled, fixed-dose study in adult smokers. Ann Gen Psychiatry. 2012 Mar 9;11(1):6. PMID: 22405499.

 

Economidou D, Dalley JW, Everitt BJ. Selective norepinephrine reuptake inhibition by atomoxetine prevents cue-induced heroin and cocaine seeking. Biol Psychiatry. 2011 Feb 1;69(3):266-74. PMID: 21109233.

 

Ludolph AG, Udvardi PT, Schaz U, et al. Atomoxetine acts as an NMDA receptor blocker in clinically relevant concentrations. Br J Pharmacol. 2010 May;160(2):283-91. PMID: 20423340.

" "UN number: 2811     Class: 6.1     Packing Group: III

Proper shipping name: Toxic solid, organic, n.o.s. (Atomoxetine hydrochloride)"

LKT A7656 Atomoxetine Hydrochloride 100 mg 525 NET and SERT inhibitor, NMDA antagonist. Strattera, tomoxetine, attentin 82248-59-7 ≥98% 291.82 C17H21NO HCl CC1=CC=CC=C1OC(CCNC)C2=CC=CC=C2.Cl Ambient Ambient Soluble in water (27.8mg/mL). DMSO 58 mg/mL. Ethanol 37 mg/mL. Chloroform, methanol. "Isaksson J, Hogmark A, Nilsson KW, et al. Effects of stimulants and atomoxetine on cortisol levels in children with ADHD. Psychiatry Res. 2013 Jul 11. pii: S0165-1781 PMID: 23850434.

 

Ercan ES, Akyol Ardic U, Kabukcu Basay B, et al. Atomoxetine response in the inattentive and combined subtypes of attention deficit hyperactivity disorder: a retrospective chart review. Atten Defic Hyperact Disord. 2013 Jun 5. [Epub ahead of print]. PMID: 23737214.

 

Silverstone PH, Dadashova R. Atomoxetine treatment for nicotine withdrawal: a pilot double-blind, placebo-controlled, fixed-dose study in adult smokers. Ann Gen Psychiatry. 2012 Mar 9;11(1):6. PMID: 22405499.

 

Economidou D, Dalley JW, Everitt BJ. Selective norepinephrine reuptake inhibition by atomoxetine prevents cue-induced heroin and cocaine seeking. Biol Psychiatry. 2011 Feb 1;69(3):266-74. PMID: 21109233.

 

Ludolph AG, Udvardi PT, Schaz U, et al. Atomoxetine acts as an NMDA receptor blocker in clinically relevant concentrations. Br J Pharmacol. 2010 May;160(2):283-91. PMID: 20423340.

" "UN number: 2811     Class: 6.1     Packing Group: III

Proper shipping name: Toxic solid, organic, n.o.s. (Atomoxetine hydrochloride)"

LKT A7656 Atomoxetine Hydrochloride 250 mg 937.5 NET and SERT inhibitor, NMDA antagonist. Strattera, tomoxetine, attentin 82248-59-7 ≥98% 291.82 C17H21NO HCl CC1=CC=CC=C1OC(CCNC)C2=CC=CC=C2.Cl Ambient Ambient Soluble in water (27.8mg/mL). DMSO 58 mg/mL. Ethanol 37 mg/mL. Chloroform, methanol. "Isaksson J, Hogmark A, Nilsson KW, et al. Effects of stimulants and atomoxetine on cortisol levels in children with ADHD. Psychiatry Res. 2013 Jul 11. pii: S0165-1781 PMID: 23850434.

 

Ercan ES, Akyol Ardic U, Kabukcu Basay B, et al. Atomoxetine response in the inattentive and combined subtypes of attention deficit hyperactivity disorder: a retrospective chart review. Atten Defic Hyperact Disord. 2013 Jun 5. [Epub ahead of print]. PMID: 23737214.

 

Silverstone PH, Dadashova R. Atomoxetine treatment for nicotine withdrawal: a pilot double-blind, placebo-controlled, fixed-dose study in adult smokers. Ann Gen Psychiatry. 2012 Mar 9;11(1):6. PMID: 22405499.

 

Economidou D, Dalley JW, Everitt BJ. Selective norepinephrine reuptake inhibition by atomoxetine prevents cue-induced heroin and cocaine seeking. Biol Psychiatry. 2011 Feb 1;69(3):266-74. PMID: 21109233.

 

Ludolph AG, Udvardi PT, Schaz U, et al. Atomoxetine acts as an NMDA receptor blocker in clinically relevant concentrations. Br J Pharmacol. 2010 May;160(2):283-91. PMID: 20423340.

" "UN number: 2811     Class: 6.1     Packing Group: III

Proper shipping name: Toxic solid, organic, n.o.s. (Atomoxetine hydrochloride)"

LKT A7657 Atosiban Acetate 0.5 mg 210.2 Peptide, alters uterine contractility; V1/2 and OXTR antagonist. 914453-95-5 ≥95% 994.2 C43H67N11O12S2 CCC(C)C1C(=O)NC(C(=O)NC(C(=O)NC(CSSCCC(=O)NC(C(=O)N1)CC2=CC=C(C=C2)OCC)C(=O)N3CCCC3C(=O)NC(CCCN)C(=O)NCC(=O)N)CC(=O)N)C(C)O.CC(=O)O Ambient -20°C "Usta IM, Khalil A, Nassar AH. Oxytocin antagonists for the management of preterm birth: a review. Am J Perinatol. 2011 Jun;28(6):449-60. PMID: 21170825.

 

Pierzynski P. Oxytocin and vasopressin V(1A) receptors as new therapeutic targets in assisted reproduction. Reprod Biomed Online. 2011 Jan;22(1):9-16. PMID: 21130036.

" Not dangerous goods.

LKT A7657 Atosiban Acetate 1 mg 337.6 Peptide, alters uterine contractility; V1/2 and OXTR antagonist. 914453-95-5 ≥95% 994.2 C43H67N11O12S2 CCC(C)C1C(=O)NC(C(=O)NC(C(=O)NC(CSSCCC(=O)NC(C(=O)N1)CC2=CC=C(C=C2)OCC)C(=O)N3CCCC3C(=O)NC(CCCN)C(=O)NCC(=O)N)CC(=O)N)C(C)O.CC(=O)O Ambient -20°C "Usta IM, Khalil A, Nassar AH. Oxytocin antagonists for the management of preterm birth: a review. Am J Perinatol. 2011 Jun;28(6):449-60. PMID: 21170825.

 

Pierzynski P. Oxytocin and vasopressin V(1A) receptors as new therapeutic targets in assisted reproduction. Reprod Biomed Online. 2011 Jan;22(1):9-16. PMID: 21130036.

" Not dangerous goods.

LKT A7657 Atosiban Acetate 2.5 mg 421.8 Peptide, alters uterine contractility; V1/2 and OXTR antagonist. 914453-95-5 ≥95% 994.2 C43H67N11O12S2 CCC(C)C1C(=O)NC(C(=O)NC(C(=O)NC(CSSCCC(=O)NC(C(=O)N1)CC2=CC=C(C=C2)OCC)C(=O)N3CCCC3C(=O)NC(CCCN)C(=O)NCC(=O)N)CC(=O)N)C(C)O.CC(=O)O Ambient -20°C "Usta IM, Khalil A, Nassar AH. Oxytocin antagonists for the management of preterm birth: a review. Am J Perinatol. 2011 Jun;28(6):449-60. PMID: 21170825.

 

Pierzynski P. Oxytocin and vasopressin V(1A) receptors as new therapeutic targets in assisted reproduction. Reprod Biomed Online. 2011 Jan;22(1):9-16. PMID: 21130036.

" Not dangerous goods.

LKT A7658 Atorvastatin Calcium Trihydrate 10 mg 54.4 Statin; HMG-CoA reductase inhibitor. (βR,δR)-2-(4-Fluorophenyl)-β,δ-dihydroxy-5-(1- methylethyl)-3-phenyl-4-[(phenylamino)carbonyl]-1H-pyrrole-1-heptanoic acid Atorvastatin Calcium Salt; Lipitor; Sortis: Torvast; Totalip; Xarator 344423-98-9 ≥98% 1209.39 (C33H34FN2O5)2 Ca 3H2O CC(C)C1=C(C(=C(N1CCC(CC(CC(=O)[O-])O)O)C2=CC=C(C=C2)F)C3=CC=CC=C3)C(=O)NC4=CC=CC=C4.CC(C)C1=C(C(=C(N1CCC(CC(CC(=O)[O-])O)O)C2=CC=C(C=C2)F)C3=CC=CC=C3)C(=O)NC4=CC=CC=C4.O.O.O.[Ca]                                         Ambient Ambient Soluble in methanol. Very slightly soluble in water and acetonitrile. Slightly soluble in ethanol.  DMSO (10 mg/ml) "Cai J, Yu X, Zhang B, et al. Atorvastatin improves survival of implanted stem cells in a rat model of renal ischemia-reperfusion injury. Am J Nephrol. 2014;39(6):466-75. PMID: 24854145.

 

Akahori H, Tsujino T, Naito Y, et al. Atorvastatin ameliorates cardiac fibrosis and improves left ventricular diastolic function in hypertensive diastolic heart failure model rats. J Hypertens. 2014 Jul;32(7):1534-41. PMID: 24759122.

 

Lea AP, McTavish D. Atorvastatin. A review of its pharmacology and therapeutic potential in the management of hyperlipidaemias. Drugs. 1997 May;53(5):828-47. PMID: 9129869.

 

Izumi S, Nozaki Y, Maeda K, et al. Investigation of the impact of substrate selection on in vitro organic anion transporting polypeptide 1B1 inhibition profiles for the prediction of drug-drug interactions. Drug Metab Dispos. 2015 Feb;43(2):235-247. PMID: 25414411.

" None Not dangerous goods.

LKT A7658 Atorvastatin Calcium Trihydrate 50 mg 169.9 Statin; HMG-CoA reductase inhibitor. (βR,δR)-2-(4-Fluorophenyl)-β,δ-dihydroxy-5-(1- methylethyl)-3-phenyl-4-[(phenylamino)carbonyl]-1H-pyrrole-1-heptanoic acid Atorvastatin Calcium Salt; Lipitor; Sortis: Torvast; Totalip; Xarator 344423-98-9 ≥98% 1209.39 (C33H34FN2O5)2 Ca 3H2O CC(C)C1=C(C(=C(N1CCC(CC(CC(=O)[O-])O)O)C2=CC=C(C=C2)F)C3=CC=CC=C3)C(=O)NC4=CC=CC=C4.CC(C)C1=C(C(=C(N1CCC(CC(CC(=O)[O-])O)O)C2=CC=C(C=C2)F)C3=CC=CC=C3)C(=O)NC4=CC=CC=C4.O.O.O.[Ca]                                         Ambient Ambient Soluble in methanol. Very slightly soluble in water and acetonitrile. Slightly soluble in ethanol.  DMSO (10 mg/ml) "Cai J, Yu X, Zhang B, et al. Atorvastatin improves survival of implanted stem cells in a rat model of renal ischemia-reperfusion injury. Am J Nephrol. 2014;39(6):466-75. PMID: 24854145.

 

Akahori H, Tsujino T, Naito Y, et al. Atorvastatin ameliorates cardiac fibrosis and improves left ventricular diastolic function in hypertensive diastolic heart failure model rats. J Hypertens. 2014 Jul;32(7):1534-41. PMID: 24759122.

 

Lea AP, McTavish D. Atorvastatin. A review of its pharmacology and therapeutic potential in the management of hyperlipidaemias. Drugs. 1997 May;53(5):828-47. PMID: 9129869.

 

Izumi S, Nozaki Y, Maeda K, et al. Investigation of the impact of substrate selection on in vitro organic anion transporting polypeptide 1B1 inhibition profiles for the prediction of drug-drug interactions. Drug Metab Dispos. 2015 Feb;43(2):235-247. PMID: 25414411.

" None Not dangerous goods.

LKT A7658 Atorvastatin Calcium Trihydrate 100 mg 271.7 Statin; HMG-CoA reductase inhibitor. (βR,δR)-2-(4-Fluorophenyl)-β,δ-dihydroxy-5-(1- methylethyl)-3-phenyl-4-[(phenylamino)carbonyl]-1H-pyrrole-1-heptanoic acid Atorvastatin Calcium Salt; Lipitor; Sortis: Torvast; Totalip; Xarator 344423-98-9 ≥98% 1209.39 (C33H34FN2O5)2 Ca 3H2O CC(C)C1=C(C(=C(N1CCC(CC(CC(=O)[O-])O)O)C2=CC=C(C=C2)F)C3=CC=CC=C3)C(=O)NC4=CC=CC=C4.CC(C)C1=C(C(=C(N1CCC(CC(CC(=O)[O-])O)O)C2=CC=C(C=C2)F)C3=CC=CC=C3)C(=O)NC4=CC=CC=C4.O.O.O.[Ca]                                         Ambient Ambient Soluble in methanol. Very slightly soluble in water and acetonitrile. Slightly soluble in ethanol.  DMSO (10 mg/ml) "Cai J, Yu X, Zhang B, et al. Atorvastatin improves survival of implanted stem cells in a rat model of renal ischemia-reperfusion injury. Am J Nephrol. 2014;39(6):466-75. PMID: 24854145.

 

Akahori H, Tsujino T, Naito Y, et al. Atorvastatin ameliorates cardiac fibrosis and improves left ventricular diastolic function in hypertensive diastolic heart failure model rats. J Hypertens. 2014 Jul;32(7):1534-41. PMID: 24759122.

 

Lea AP, McTavish D. Atorvastatin. A review of its pharmacology and therapeutic potential in the management of hyperlipidaemias. Drugs. 1997 May;53(5):828-47. PMID: 9129869.

 

Izumi S, Nozaki Y, Maeda K, et al. Investigation of the impact of substrate selection on in vitro organic anion transporting polypeptide 1B1 inhibition profiles for the prediction of drug-drug interactions. Drug Metab Dispos. 2015 Feb;43(2):235-247. PMID: 25414411.

" None Not dangerous goods.

LKT A7668 Atracurium Besylate 50 mg 76.8 Non-depolarizing NMJ blocker; AChR antagonist. 5-[3-[1-[(3,4-dimethoxyphenyl)methyl]-6,7-dimethoxy-2-methyl-3,4-dihydro-1H-isoquinolin-2-yl]propanoyl- oxy]pentyl-3-[1-[(3,4-dimethoxyphenyl)methyl]-6,7- dimethoxy-2-methyl-3,4-dihydro-1H-isoquinolin-2- yl]propanoate BW-33A; Tracrium 64228-81-5 ≥95% 1243.49 C65H82N2O18S2 C[N+]1(CCC2=CC(=C(C=C2C1CC3=CC(=C(C=C3)OC)OC)OC)OC)CCC(=O)OCCCCCOC(=O)CC[N+]4(CCC5=CC(=C(C=C5C4CC6=CC(=C(C=C6)OC)OC)OC)OC)C.C1=CC=C(C=C1)S(=O)(=O)[O-].C1=CC=C(C=C1)S(=O)(=O)[O-] Ambient 4°C Soluble in water (27mg/mL). Soluble in DMSO (>100 mg/mL). "Shashank D, Singh NR, Singh LK. Effects of pretreatment with different neuromuscular blocking agents on facilitation of intubation with rocuronium: A prospective randomized comparative study. Indian J Anaesth. 2014 May;58(3):303-8. PMID: 25024474.

 

Jonsson M, Gurley D, Dabrowski M, et al. Distinct pharmacologic properties of neuromuscular blocking agents on human neuronal nicotinic acetylcholine receptors: a possible explanation for the train-of-four fade. Anesthesiology. 2006 Sep;105(3):521-33. PMID: 16931985.

 

Bowman WC. Neuromuscular block. Br J Pharmacol. 2006 Jan;147 Suppl 1:S277-86. PMID: 16402115.

" Xn Xi Not dangerous goods.

LKT A7668 Atracurium Besylate 100 mg 123.8 Non-depolarizing NMJ blocker; AChR antagonist. 5-[3-[1-[(3,4-dimethoxyphenyl)methyl]-6,7-dimethoxy-2-methyl-3,4-dihydro-1H-isoquinolin-2-yl]propanoyl- oxy]pentyl-3-[1-[(3,4-dimethoxyphenyl)methyl]-6,7- dimethoxy-2-methyl-3,4-dihydro-1H-isoquinolin-2- yl]propanoate BW-33A; Tracrium 64228-81-5 ≥95% 1243.49 C65H82N2O18S2 C[N+]1(CCC2=CC(=C(C=C2C1CC3=CC(=C(C=C3)OC)OC)OC)OC)CCC(=O)OCCCCCOC(=O)CC[N+]4(CCC5=CC(=C(C=C5C4CC6=CC(=C(C=C6)OC)OC)OC)OC)C.C1=CC=C(C=C1)S(=O)(=O)[O-].C1=CC=C(C=C1)S(=O)(=O)[O-] Ambient 4°C Soluble in water (27mg/mL). Soluble in DMSO (>100 mg/mL). "Shashank D, Singh NR, Singh LK. Effects of pretreatment with different neuromuscular blocking agents on facilitation of intubation with rocuronium: A prospective randomized comparative study. Indian J Anaesth. 2014 May;58(3):303-8. PMID: 25024474.

 

Jonsson M, Gurley D, Dabrowski M, et al. Distinct pharmacologic properties of neuromuscular blocking agents on human neuronal nicotinic acetylcholine receptors: a possible explanation for the train-of-four fade. Anesthesiology. 2006 Sep;105(3):521-33. PMID: 16931985.

 

Bowman WC. Neuromuscular block. Br J Pharmacol. 2006 Jan;147 Suppl 1:S277-86. PMID: 16402115.

" Xn Xi Not dangerous goods.

LKT A7668 Atracurium Besylate 500 mg 480.3 Non-depolarizing NMJ blocker; AChR antagonist. 5-[3-[1-[(3,4-dimethoxyphenyl)methyl]-6,7-dimethoxy-2-methyl-3,4-dihydro-1H-isoquinolin-2-yl]propanoyl- oxy]pentyl-3-[1-[(3,4-dimethoxyphenyl)methyl]-6,7- dimethoxy-2-methyl-3,4-dihydro-1H-isoquinolin-2- yl]propanoate BW-33A; Tracrium 64228-81-5 ≥95% 1243.49 C65H82N2O18S2 C[N+]1(CCC2=CC(=C(C=C2C1CC3=CC(=C(C=C3)OC)OC)OC)OC)CCC(=O)OCCCCCOC(=O)CC[N+]4(CCC5=CC(=C(C=C5C4CC6=CC(=C(C=C6)OC)OC)OC)OC)C.C1=CC=C(C=C1)S(=O)(=O)[O-].C1=CC=C(C=C1)S(=O)(=O)[O-] Ambient 4°C Soluble in water (27mg/mL). Soluble in DMSO (>100 mg/mL). "Shashank D, Singh NR, Singh LK. Effects of pretreatment with different neuromuscular blocking agents on facilitation of intubation with rocuronium: A prospective randomized comparative study. Indian J Anaesth. 2014 May;58(3):303-8. PMID: 25024474.

 

Jonsson M, Gurley D, Dabrowski M, et al. Distinct pharmacologic properties of neuromuscular blocking agents on human neuronal nicotinic acetylcholine receptors: a possible explanation for the train-of-four fade. Anesthesiology. 2006 Sep;105(3):521-33. PMID: 16931985.

 

Bowman WC. Neuromuscular block. Br J Pharmacol. 2006 Jan;147 Suppl 1:S277-86. PMID: 16402115.

" Xn Xi Not dangerous goods.

LKT A7669 A-type Natriuretic Peptide (1-28), rat 0.5 mg 287.9 Endogenous cardiomodulatory peptide; NPR-A agonist. ANP; Atrial natriuretic peptide 88898-17-3 ≥95% 3062.47 C128H205N45O39S2 CCC(C)C1C(=O)NCC(=O)NC(C(=O)NC(C(=O)NC(C(=O)NCC(=O)NC(C(=O)NCC(=O)NC(CSSCC(C(=O)NC(C(=O)NCC(=O)NCC(=O)NC(C(=O)NC(C(=O)NC(C(=O)NC(C(=O)N1)CCCNC(=N)N)CC(=O)O)C(C)CC)CCCNC(=N)N)CC2=CC=CC=C2)NC(=O)C(CO)NC(=O)C(CO)NC(=O)C(CCCNC(=N)N)NC(=O)C(CCCNC(=N)N)NC(=O)C(CC(C)C)NC(=O)C(CO)N)C(=O)NC(CC(=O)N)C(=O)NC(CO)C(=O)NC(CC3=CC=CC=C3)C(=O)NC(CCCNC(=N)N)C(=O)NC(CC4=CC=C(C=C4)O)C(=O)O)CC(C)C)CO)CCC(=O)N)C Ambient -20°C "Vesely DL. New anticancer agents: hormones made within the heart. Anticancer Res. 2012 Jul;32(7):2515-21. PMID: 22753708.

 

Woodard GE, Rosado JA. Natriuretic peptides in vascular physiology and pathology. Int Rev Cell Mol Biol. 2008;268:59-93. PMID: 18703404.

" Not dangerous goods.

LKT A7669 A-type Natriuretic Peptide (1-28), rat 1 mg 489.1 Endogenous cardiomodulatory peptide; NPR-A agonist. ANP; Atrial natriuretic peptide 88898-17-3 ≥95% 3062.47 C128H205N45O39S2 CCC(C)C1C(=O)NCC(=O)NC(C(=O)NC(C(=O)NC(C(=O)NCC(=O)NC(C(=O)NCC(=O)NC(CSSCC(C(=O)NC(C(=O)NCC(=O)NCC(=O)NC(C(=O)NC(C(=O)NC(C(=O)NC(C(=O)N1)CCCNC(=N)N)CC(=O)O)C(C)CC)CCCNC(=N)N)CC2=CC=CC=C2)NC(=O)C(CO)NC(=O)C(CO)NC(=O)C(CCCNC(=N)N)NC(=O)C(CCCNC(=N)N)NC(=O)C(CC(C)C)NC(=O)C(CO)N)C(=O)NC(CC(=O)N)C(=O)NC(CO)C(=O)NC(CC3=CC=CC=C3)C(=O)NC(CCCNC(=N)N)C(=O)NC(CC4=CC=C(C=C4)O)C(=O)O)CC(C)C)CO)CCC(=O)N)C Ambient -20°C "Vesely DL. New anticancer agents: hormones made within the heart. Anticancer Res. 2012 Jul;32(7):2515-21. PMID: 22753708.

 

Woodard GE, Rosado JA. Natriuretic peptides in vascular physiology and pathology. Int Rev Cell Mol Biol. 2008;268:59-93. PMID: 18703404.

" Not dangerous goods.

LKT A7669 A-type Natriuretic Peptide (1-28), rat 2.5 mg 864 Endogenous cardiomodulatory peptide; NPR-A agonist. ANP; Atrial natriuretic peptide 88898-17-3 ≥95% 3062.47 C128H205N45O39S2 CCC(C)C1C(=O)NCC(=O)NC(C(=O)NC(C(=O)NC(C(=O)NCC(=O)NC(C(=O)NCC(=O)NC(CSSCC(C(=O)NC(C(=O)NCC(=O)NCC(=O)NC(C(=O)NC(C(=O)NC(C(=O)NC(C(=O)N1)CCCNC(=N)N)CC(=O)O)C(C)CC)CCCNC(=N)N)CC2=CC=CC=C2)NC(=O)C(CO)NC(=O)C(CO)NC(=O)C(CCCNC(=N)N)NC(=O)C(CCCNC(=N)N)NC(=O)C(CC(C)C)NC(=O)C(CO)N)C(=O)NC(CC(=O)N)C(=O)NC(CO)C(=O)NC(CC3=CC=CC=C3)C(=O)NC(CCCNC(=N)N)C(=O)NC(CC4=CC=C(C=C4)O)C(=O)O)CC(C)C)CO)CCC(=O)N)C Ambient -20°C "Vesely DL. New anticancer agents: hormones made within the heart. Anticancer Res. 2012 Jul;32(7):2515-21. PMID: 22753708.

 

Woodard GE, Rosado JA. Natriuretic peptides in vascular physiology and pathology. Int Rev Cell Mol Biol. 2008;268:59-93. PMID: 18703404.

" Not dangerous goods.

LKT A7670 Atriopeptin I 0.5 mg 204.1 ANP analog, cardiomodulatory peptide; weak NPR-A agonist. ≥95% 2083.31 C83H135N29O30S2 CCC(C)C1C(=O)NCC(=O)NC(C(=O)NC(C(=O)NC(C(=O)NCC(=O)NC(C(=O)NCC(=O)NC(CSSCC(C(=O)NC(C(=O)NCC(=O)NCC(=O)NC(C(=O)NC(C(=O)NC(C(=O)NC(C(=O)N1)CCCNC(=N)N)CC(=O)O)C(C)CC)CCCNC(=N)N)CC2=CC=CC=C2)NC(=O)C(CO)NC(=O)C(CO)N)C(=O)NC(CC(=O)N)C(=O)NC(CO)C(=O)O)CC(C)C)CO)CCC(=O)N)C Ambient -20°C "Stewart AG, Thompson JS, Rogers TK, et al. Atrial natriuretic peptide-induced relaxation of pre-constricted isolated rat perfused lungs: a comparison in control and hypoxia-adapted animals. Clin Sci (Lond). 1991 Aug;81(2):201-8. PMID: 1653664.

 

Numan NA, Gillespie MN, Altiere RJ. Pulmonary vasorelaxant activity of atrial peptides. Pulm Pharmacol. 1990;3(1):29-33. PMID: 1966900.

" Not dangerous goods.

LKT A7670 Atriopeptin I 1 mg 348 ANP analog, cardiomodulatory peptide; weak NPR-A agonist. ≥95% 2083.31 C83H135N29O30S2 CCC(C)C1C(=O)NCC(=O)NC(C(=O)NC(C(=O)NC(C(=O)NCC(=O)NC(C(=O)NCC(=O)NC(CSSCC(C(=O)NC(C(=O)NCC(=O)NCC(=O)NC(C(=O)NC(C(=O)NC(C(=O)NC(C(=O)N1)CCCNC(=N)N)CC(=O)O)C(C)CC)CCCNC(=N)N)CC2=CC=CC=C2)NC(=O)C(CO)NC(=O)C(CO)N)C(=O)NC(CC(=O)N)C(=O)NC(CO)C(=O)O)CC(C)C)CO)CCC(=O)N)C Ambient -20°C "Stewart AG, Thompson JS, Rogers TK, et al. Atrial natriuretic peptide-induced relaxation of pre-constricted isolated rat perfused lungs: a comparison in control and hypoxia-adapted animals. Clin Sci (Lond). 1991 Aug;81(2):201-8. PMID: 1653664.

 

Numan NA, Gillespie MN, Altiere RJ. Pulmonary vasorelaxant activity of atrial peptides. Pulm Pharmacol. 1990;3(1):29-33. PMID: 1966900.

" Not dangerous goods.

LKT A7670 Atriopeptin I 2.5 mg 612.4 ANP analog, cardiomodulatory peptide; weak NPR-A agonist. ≥95% 2083.31 C83H135N29O30S2 CCC(C)C1C(=O)NCC(=O)NC(C(=O)NC(C(=O)NC(C(=O)NCC(=O)NC(C(=O)NCC(=O)NC(CSSCC(C(=O)NC(C(=O)NCC(=O)NCC(=O)NC(C(=O)NC(C(=O)NC(C(=O)NC(C(=O)N1)CCCNC(=N)N)CC(=O)O)C(C)CC)CCCNC(=N)N)CC2=CC=CC=C2)NC(=O)C(CO)NC(=O)C(CO)N)C(=O)NC(CC(=O)N)C(=O)NC(CO)C(=O)O)CC(C)C)CO)CCC(=O)N)C Ambient -20°C "Stewart AG, Thompson JS, Rogers TK, et al. Atrial natriuretic peptide-induced relaxation of pre-constricted isolated rat perfused lungs: a comparison in control and hypoxia-adapted animals. Clin Sci (Lond). 1991 Aug;81(2):201-8. PMID: 1653664.

 

Numan NA, Gillespie MN, Altiere RJ. Pulmonary vasorelaxant activity of atrial peptides. Pulm Pharmacol. 1990;3(1):29-33. PMID: 1966900.

" Not dangerous goods.

LKT A7672 Atropine Sulfate Monohydrate 5 g 88.3 Tropane alkaloid found in Solanaceae plants; mAChR antagonist. α-(Hydroxymethyl)benzeneacetic acid (3-endo)-8- methyl-8-azabicyclo[3.2.1]oct-3-yl ester sulfate monohydrate Atropine sulfate monohydrate; Atropisol; Atropt 5908-99-6 ≥98% 694.84 (C17H23NO3)2 H2SO4 H2O CN1C2CCC1CC(C2)OC(=O)C(CO)C3=CC=CC=C3CN1C2CCC1CC(C2)OC(=O)C(CO)C3=CC=CC=C3.O.OS(=O)(=O)O Ambient Ambient Soluble in water (2 g/mL),ethanol (200 mg/mL) chloroform (1g/420mL) or glycerol (400 mg/mL). "Ghelardini C, Malmberg-Aiello P, Giotti A, et al. Investigation into atropine-induced antinociception. Br J Pharmacol. 1990 Sep;101(1):49-54. PMID: 2282466.

 

Alberts P, Ogren VR. Interaction of forskolin with the effect of atropine on [3H]acetylcholine secretion in guinea-pig ileum myenteric plexus. J Physiol. 1988 Jan;395:441-53. PMID: 2457681.

 

Berti F, Folco GC, Giachetti A, et al. Atropine inhibits thromboxane A2 generation in isolated lungs of the guinea-pig. Br J Pharmacol. 1980 Mar;68(3):467-72. PMID: 7052339.

" Xi, T+ "UN number: 1544     Class: 6.1     Packing Group:  II

Proper shipping name: Atropine Sulfate Monohydrate

Marine pollutant: No     Poison Inhalation Hazard: No"

LKT A7672 Atropine Sulfate Monohydrate 10 g 136 Tropane alkaloid found in Solanaceae plants; mAChR antagonist. α-(Hydroxymethyl)benzeneacetic acid (3-endo)-8- methyl-8-azabicyclo[3.2.1]oct-3-yl ester sulfate monohydrate Atropine sulfate monohydrate; Atropisol; Atropt 5908-99-6 ≥98% 694.84 (C17H23NO3)2 H2SO4 H2O CN1C2CCC1CC(C2)OC(=O)C(CO)C3=CC=CC=C3CN1C2CCC1CC(C2)OC(=O)C(CO)C3=CC=CC=C3.O.OS(=O)(=O)O Ambient Ambient Soluble in water (2 g/mL),ethanol (200 mg/mL) chloroform (1g/420mL) or glycerol (400 mg/mL). "Ghelardini C, Malmberg-Aiello P, Giotti A, et al. Investigation into atropine-induced antinociception. Br J Pharmacol. 1990 Sep;101(1):49-54. PMID: 2282466.

 

Alberts P, Ogren VR. Interaction of forskolin with the effect of atropine on [3H]acetylcholine secretion in guinea-pig ileum myenteric plexus. J Physiol. 1988 Jan;395:441-53. PMID: 2457681.

 

Berti F, Folco GC, Giachetti A, et al. Atropine inhibits thromboxane A2 generation in isolated lungs of the guinea-pig. Br J Pharmacol. 1980 Mar;68(3):467-72. PMID: 7052339.

" Xi, T+ "UN number: 1544     Class: 6.1     Packing Group:  II

Proper shipping name: Atropine Sulfate Monohydrate

Marine pollutant: No     Poison Inhalation Hazard: No"

LKT A7672 Atropine Sulfate Monohydrate 25 g 216 Tropane alkaloid found in Solanaceae plants; mAChR antagonist. α-(Hydroxymethyl)benzeneacetic acid (3-endo)-8- methyl-8-azabicyclo[3.2.1]oct-3-yl ester sulfate monohydrate Atropine sulfate monohydrate; Atropisol; Atropt 5908-99-6 ≥98% 694.84 (C17H23NO3)2 H2SO4 H2O CN1C2CCC1CC(C2)OC(=O)C(CO)C3=CC=CC=C3CN1C2CCC1CC(C2)OC(=O)C(CO)C3=CC=CC=C3.O.OS(=O)(=O)O Ambient Ambient Soluble in water (2 g/mL),ethanol (200 mg/mL) chloroform (1g/420mL) or glycerol (400 mg/mL). "Ghelardini C, Malmberg-Aiello P, Giotti A, et al. Investigation into atropine-induced antinociception. Br J Pharmacol. 1990 Sep;101(1):49-54. PMID: 2282466.

 

Alberts P, Ogren VR. Interaction of forskolin with the effect of atropine on [3H]acetylcholine secretion in guinea-pig ileum myenteric plexus. J Physiol. 1988 Jan;395:441-53. PMID: 2457681.

 

Berti F, Folco GC, Giachetti A, et al. Atropine inhibits thromboxane A2 generation in isolated lungs of the guinea-pig. Br J Pharmacol. 1980 Mar;68(3):467-72. PMID: 7052339.

" Xi, T+ "UN number: 1544     Class: 6.1     Packing Group:  II

Proper shipping name: Atropine Sulfate Monohydrate

Marine pollutant: No     Poison Inhalation Hazard: No"

LKT A8070 Auraptene 25 mg 67.9 Monoterpene coumarin ether found in Citrus; PPARα agonist, ACAT inhibitor. 7-Geranyloxycoumarin; Aurapten 495-02-3 ≥98% 298.38 C19H22O3 CC(=CCCC(=CCOC1=CC2=C(C=C1)C=CC(=O)O2)C)C Ambient -20°C Soluble in methanol, ethanol, DMSO (50mM), and ethyl acetate.  Insoluble in water. "Okuyama S, Yamamoto K, Mori H, et al. Auraptene in the Peels of Citrus kawachiensis (Kawachi Bankan) Ameliorates Lipopolysaccharide-Induced Inflammation in the Mouse Brain. Evid Based Complement Alternat Med. 2014;2014:408503. PMID: 24955102.

 

Imenshahidi M, Eghbal M, Sahebkar A, et al. Hypotensive activity of auraptene, a monoterpene coumarin from Citrus spp. Pharm Biol. 2013 May;51(5):545-9. PMID: 23368941.

 

Okuyama S, Minami S, Shimada N, et al. Anti-inflammatory and neuroprotective effects of auraptene, a citrus coumarin, following cerebral global ischemia in mice. Eur J Pharmacol. 2013 Jan 15;699(1-3):118-23. PMID: 23219792.

 

Krishnan P, Kleiner-Hancock H. Effects of Auraptene on IGF-1 Stimulated Cell Cycle Progression in the Human Breast Cancer Cell Line, MCF-7. Int J Breast Cancer. 2012;2012:502092. PMID: 23320178.

 

Takahashi N, Senda M, Lin S, et al. Auraptene regulates gene expression involved in lipid metabolism through PPARα activation in diabetic obese mice. Mol Nutr Food Res. 2011 Dec;55(12):1791-7. PMID: 22038981.

 

de Medina P, Genovese S, Paillasse MR, et al. Auraptene is an inhibitor of cholesterol esterification and a modulator of estrogen receptors. Mol Pharmacol. 2010 Nov;78(5):827-36. PMID: 20702762.

 

Napolitano HB, Silva M, Ellena J, et al. Aurapten, a coumarin with growth inhibition against Leishmania major promastigotes. Braz J Med Biol Res. 2004 Dec;37(12):1847-52. PMID: 15558191.

" Not dangerous goods.

LKT A8070 Auraptene 100 mg 224.3 Monoterpene coumarin ether found in Citrus; PPARα agonist, ACAT inhibitor. 7-Geranyloxycoumarin; Aurapten 495-02-3 ≥98% 298.38 C19H22O3 CC(=CCCC(=CCOC1=CC2=C(C=C1)C=CC(=O)O2)C)C Ambient -20°C Soluble in methanol, ethanol, DMSO (50mM), and ethyl acetate.  Insoluble in water. "Okuyama S, Yamamoto K, Mori H, et al. Auraptene in the Peels of Citrus kawachiensis (Kawachi Bankan) Ameliorates Lipopolysaccharide-Induced Inflammation in the Mouse Brain. Evid Based Complement Alternat Med. 2014;2014:408503. PMID: 24955102.

 

Imenshahidi M, Eghbal M, Sahebkar A, et al. Hypotensive activity of auraptene, a monoterpene coumarin from Citrus spp. Pharm Biol. 2013 May;51(5):545-9. PMID: 23368941.

 

Okuyama S, Minami S, Shimada N, et al. Anti-inflammatory and neuroprotective effects of auraptene, a citrus coumarin, following cerebral global ischemia in mice. Eur J Pharmacol. 2013 Jan 15;699(1-3):118-23. PMID: 23219792.

 

Krishnan P, Kleiner-Hancock H. Effects of Auraptene on IGF-1 Stimulated Cell Cycle Progression in the Human Breast Cancer Cell Line, MCF-7. Int J Breast Cancer. 2012;2012:502092. PMID: 23320178.

 

Takahashi N, Senda M, Lin S, et al. Auraptene regulates gene expression involved in lipid metabolism through PPARα activation in diabetic obese mice. Mol Nutr Food Res. 2011 Dec;55(12):1791-7. PMID: 22038981.

 

de Medina P, Genovese S, Paillasse MR, et al. Auraptene is an inhibitor of cholesterol esterification and a modulator of estrogen receptors. Mol Pharmacol. 2010 Nov;78(5):827-36. PMID: 20702762.

 

Napolitano HB, Silva M, Ellena J, et al. Aurapten, a coumarin with growth inhibition against Leishmania major promastigotes. Braz J Med Biol Res. 2004 Dec;37(12):1847-52. PMID: 15558191.

" Not dangerous goods.

LKT A8070 Auraptene 500 mg 713.5 Monoterpene coumarin ether found in Citrus; PPARα agonist, ACAT inhibitor. 7-Geranyloxycoumarin; Aurapten 495-02-3 ≥98% 298.38 C19H22O3 CC(=CCCC(=CCOC1=CC2=C(C=C1)C=CC(=O)O2)C)C Ambient -20°C Soluble in methanol, ethanol, DMSO (50mM), and ethyl acetate.  Insoluble in water. "Okuyama S, Yamamoto K, Mori H, et al. Auraptene in the Peels of Citrus kawachiensis (Kawachi Bankan) Ameliorates Lipopolysaccharide-Induced Inflammation in the Mouse Brain. Evid Based Complement Alternat Med. 2014;2014:408503. PMID: 24955102.

 

Imenshahidi M, Eghbal M, Sahebkar A, et al. Hypotensive activity of auraptene, a monoterpene coumarin from Citrus spp. Pharm Biol. 2013 May;51(5):545-9. PMID: 23368941.

 

Okuyama S, Minami S, Shimada N, et al. Anti-inflammatory and neuroprotective effects of auraptene, a citrus coumarin, following cerebral global ischemia in mice. Eur J Pharmacol. 2013 Jan 15;699(1-3):118-23. PMID: 23219792.

 

Krishnan P, Kleiner-Hancock H. Effects of Auraptene on IGF-1 Stimulated Cell Cycle Progression in the Human Breast Cancer Cell Line, MCF-7. Int J Breast Cancer. 2012;2012:502092. PMID: 23320178.

 

Takahashi N, Senda M, Lin S, et al. Auraptene regulates gene expression involved in lipid metabolism through PPARα activation in diabetic obese mice. Mol Nutr Food Res. 2011 Dec;55(12):1791-7. PMID: 22038981.

 

de Medina P, Genovese S, Paillasse MR, et al. Auraptene is an inhibitor of cholesterol esterification and a modulator of estrogen receptors. Mol Pharmacol. 2010 Nov;78(5):827-36. PMID: 20702762.

 

Napolitano HB, Silva M, Ellena J, et al. Aurapten, a coumarin with growth inhibition against Leishmania major promastigotes. Braz J Med Biol Res. 2004 Dec;37(12):1847-52. PMID: 15558191.

" Not dangerous goods.

LKT A8071 Auriculin A 0.5 mg 276.2 Synthetic peptide, ANP analog; NPR-A agonist. ≥95% 2542.86 C104H168N38O33S2 CCC(C)C1C(=O)NCC(=O)NC(C(=O)NC(C(=O)NC(C(=O)NCC(=O)NC(C(=O)NCC(=O)NC(CSSCC(C(=O)NC(C(=O)NCC(=O)NCC(=O)NC(C(=O)NC(C(=O)NC(C(=O)NC(C(=O)N1)CCCNC(=N)N)CC(=O)O)C(C)CC)CCCNC(=N)N)CC2=CC=CC=C2)NC(=O)C(CO)NC(=O)C(CO)NC(=O)C(CCCNC(=N)N)N)C(=O)NC(CC(=O)N)C(=O)NC(CO)C(=O)NC(CC3=CC=CC=C3)C(=O)NC(CCCNC(=N)N)C(=O)O)CC(C)C)CO)CCC(=O)N)C Ambient -20°C "Emmeluth C, Eiken P, Johannessen AC, et al. Effects of atrial natriuretic peptides and furosemide in conscious dogs. Proc Soc Exp Biol Med. 1987 Oct;186(1):103-12. PMID: 2957698.

 

Volpe M, Cuocolo A, Vecchione F, et al. Vagal mediation of the effects of atrial natriuretic factor on blood pressure and arterial baroreflexes in the rabbit. Circ Res. 1987 May;60(5):747-55. PMID: 2954718.

"

LKT A8071 Auriculin A 1 mg 468.2 Synthetic peptide, ANP analog; NPR-A agonist. ≥95% 2542.86 C104H168N38O33S2 CCC(C)C1C(=O)NCC(=O)NC(C(=O)NC(C(=O)NC(C(=O)NCC(=O)NC(C(=O)NCC(=O)NC(CSSCC(C(=O)NC(C(=O)NCC(=O)NCC(=O)NC(C(=O)NC(C(=O)NC(C(=O)NC(C(=O)N1)CCCNC(=N)N)CC(=O)O)C(C)CC)CCCNC(=N)N)CC2=CC=CC=C2)NC(=O)C(CO)NC(=O)C(CO)NC(=O)C(CCCNC(=N)N)N)C(=O)NC(CC(=O)N)C(=O)NC(CO)C(=O)NC(CC3=CC=CC=C3)C(=O)NC(CCCNC(=N)N)C(=O)O)CC(C)C)CO)CCC(=O)N)C Ambient -20°C "Emmeluth C, Eiken P, Johannessen AC, et al. Effects of atrial natriuretic peptides and furosemide in conscious dogs. Proc Soc Exp Biol Med. 1987 Oct;186(1):103-12. PMID: 2957698.

 

Volpe M, Cuocolo A, Vecchione F, et al. Vagal mediation of the effects of atrial natriuretic factor on blood pressure and arterial baroreflexes in the rabbit. Circ Res. 1987 May;60(5):747-55. PMID: 2954718.

"

LKT A8071 Auriculin A 2.5 mg 828.1 Synthetic peptide, ANP analog; NPR-A agonist. ≥95% 2542.86 C104H168N38O33S2 CCC(C)C1C(=O)NCC(=O)NC(C(=O)NC(C(=O)NC(C(=O)NCC(=O)NC(C(=O)NCC(=O)NC(CSSCC(C(=O)NC(C(=O)NCC(=O)NCC(=O)NC(C(=O)NC(C(=O)NC(C(=O)NC(C(=O)N1)CCCNC(=N)N)CC(=O)O)C(C)CC)CCCNC(=N)N)CC2=CC=CC=C2)NC(=O)C(CO)NC(=O)C(CO)NC(=O)C(CCCNC(=N)N)N)C(=O)NC(CC(=O)N)C(=O)NC(CO)C(=O)NC(CC3=CC=CC=C3)C(=O)NC(CCCNC(=N)N)C(=O)O)CC(C)C)CO)CCC(=O)N)C Ambient -20°C "Emmeluth C, Eiken P, Johannessen AC, et al. Effects of atrial natriuretic peptides and furosemide in conscious dogs. Proc Soc Exp Biol Med. 1987 Oct;186(1):103-12. PMID: 2957698.

 

Volpe M, Cuocolo A, Vecchione F, et al. Vagal mediation of the effects of atrial natriuretic factor on blood pressure and arterial baroreflexes in the rabbit. Circ Res. 1987 May;60(5):747-55. PMID: 2954718.

"

LKT A8077 Autocamtide 2 0.5 mg 107.8 Peptide, CamKII substrate. 129198-88-5 ≥95% 1527.8 C65H118N22O20 CC(C)CC(C(=O)NC(CCCN=C(N)N)C(=O)NC(CCCN=C(N)N)C(=O)NC(CCC(=O)N)C(=O)NC(CCC(=O)O)C(=O)NC(C(C)O)C(=O)NC(C(C)C)C(=O)NC(CC(=O)O)C(=O)NC(C)C(=O)NC(CC(C)C)C(=O)O)NC(=O)C(C)NC(=O)C(CCCCN)NC(=O)C(CCCCN)N Ambient -20°C Cooper NG, Laabich A, Fan W, et al. The relationship between neurotrophic factors and CaMKII in the death and survival of retinal ganglion cells. Prog Brain Res. 2008;173:521-40. PMID: 18929132. Not dangerous goods.

LKT A8077 Autocamtide 2 1 mg 183 Peptide, CamKII substrate. 129198-88-5 ≥95% 1527.8 C65H118N22O20 CC(C)CC(C(=O)NC(CCCN=C(N)N)C(=O)NC(CCCN=C(N)N)C(=O)NC(CCC(=O)N)C(=O)NC(CCC(=O)O)C(=O)NC(C(C)O)C(=O)NC(C(C)C)C(=O)NC(CC(=O)O)C(=O)NC(C)C(=O)NC(CC(C)C)C(=O)O)NC(=O)C(C)NC(=O)C(CCCCN)NC(=O)C(CCCCN)N Ambient -20°C Cooper NG, Laabich A, Fan W, et al. The relationship between neurotrophic factors and CaMKII in the death and survival of retinal ganglion cells. Prog Brain Res. 2008;173:521-40. PMID: 18929132. Not dangerous goods.

LKT A8077 Autocamtide 2 2.5 mg 324 Peptide, CamKII substrate. 129198-88-5 ≥95% 1527.8 C65H118N22O20 CC(C)CC(C(=O)NC(CCCN=C(N)N)C(=O)NC(CCCN=C(N)N)C(=O)NC(CCC(=O)N)C(=O)NC(CCC(=O)O)C(=O)NC(C(C)O)C(=O)NC(C(C)C)C(=O)NC(CC(=O)O)C(=O)NC(C)C(=O)NC(CC(C)C)C(=O)O)NC(=O)C(C)NC(=O)C(CCCCN)NC(=O)C(CCCCN)N Ambient -20°C Cooper NG, Laabich A, Fan W, et al. The relationship between neurotrophic factors and CaMKII in the death and survival of retinal ganglion cells. Prog Brain Res. 2008;173:521-40. PMID: 18929132. Not dangerous goods.

LKT A9602 Azacitidine 100 mg 39.5 Nucleoside (cytidine) analog; DNMT inhibitor, protein synthesis inhibitor. 4-amino-1-β-D-ribofuranosyl-1,3,5-triazin-2(1H)-one 320-67-2 ≥98% 244.2 C8H12N4O5 C1=NC(=NC(=O)N1C2C(C(C(O2)CO)O)O)N "The half-life of the 

compound in phosphate buffered saline, pH 7.4,when heated to 50°C is 90 minutes. Prepare fresh stock solution for each usage, and keep at 0°C until used." Ambient Ambient Soluble in water, but unstable. "Borodovsky A, Salmasi V, Turcan S, et al. 5-azacytidine reduces methylation, promotes differentiation and induces tumor regression in a patient-derived IDH1 mutant glioma xenograft. Oncotarget. 2013 Oct;4(10):1737-47. PMID: 24077805.

 

Solís-Paredes M, Eguía-Aguilar P, Chico-Ponce de León F, et al. Epigenetic modifications in cell lines of human astrocytoma differentially regulate expression of apoptotic genes. Childs Nerv Syst. 2013 Aug 13. Epub ahead of print. PMID: 23943192.

 

Tsujioka T, Yokoi A, Uesugi M, et al. Effects of DNA methyltransferase inhibitors (DNMTIs) on MDS-derived cell lines. Exp Hematol. 2013 Feb;41(2):189-97. PMID: 23085465.

 

Kimura S, Kuramoto K, Homan J, et al. Antiproliferative and antitumor effects of azacitidine against the human myelodysplastic syndrome cell line SKM-1. Anticancer Res. 2012 Mar;32(3):795-8. PMID: 22399596.

 

Goodyear OC, Dennis M, Jilani NY, et al. Azacitidine augments expansion of regulatory T cells after allogeneic stem cell transplantation in patients with acute myeloid leukemia (AML). Blood. 2012 Apr 5;119(14):3361-9. PMID: 22234690.

 

Ye NS, Chen J, Luo GA, et al. Proteomic profiling of rat bone marrow mesenchymal stem cells induced by 5-azacytidine. Stem Cells ev. 2006 Oct;15(5):665-76. PMID: 17105402.

 

Bouchard J, Walker MC, Leclerc JM, et al. 5-azacytidine and 5-azadeoxycytidine inhibit human immunodeficiency virus type 1 replication in vitro. Antimicrob Agents Chemother. 1990 Feb;34(2):206-9. PMID: 1691617.

" T, Xn, Carc. Not dangerous goods.

LKT A9602 Azacitidine 250 mg 92.5 Nucleoside (cytidine) analog; DNMT inhibitor, protein synthesis inhibitor. 4-amino-1-β-D-ribofuranosyl-1,3,5-triazin-2(1H)-one 320-67-2 ≥98% 244.2 C8H12N4O5 C1=NC(=NC(=O)N1C2C(C(C(O2)CO)O)O)N "The half-life of the 

compound in phosphate buffered saline, pH 7.4,when heated to 50°C is 90 minutes. Prepare fresh stock solution for each usage, and keep at 0°C until used." Ambient Ambient Soluble in water, but unstable. "Borodovsky A, Salmasi V, Turcan S, et al. 5-azacytidine reduces methylation, promotes differentiation and induces tumor regression in a patient-derived IDH1 mutant glioma xenograft. Oncotarget. 2013 Oct;4(10):1737-47. PMID: 24077805.

 

Solís-Paredes M, Eguía-Aguilar P, Chico-Ponce de León F, et al. Epigenetic modifications in cell lines of human astrocytoma differentially regulate expression of apoptotic genes. Childs Nerv Syst. 2013 Aug 13. Epub ahead of print. PMID: 23943192.

 

Tsujioka T, Yokoi A, Uesugi M, et al. Effects of DNA methyltransferase inhibitors (DNMTIs) on MDS-derived cell lines. Exp Hematol. 2013 Feb;41(2):189-97. PMID: 23085465.

 

Kimura S, Kuramoto K, Homan J, et al. Antiproliferative and antitumor effects of azacitidine against the human myelodysplastic syndrome cell line SKM-1. Anticancer Res. 2012 Mar;32(3):795-8. PMID: 22399596.

 

Goodyear OC, Dennis M, Jilani NY, et al. Azacitidine augments expansion of regulatory T cells after allogeneic stem cell transplantation in patients with acute myeloid leukemia (AML). Blood. 2012 Apr 5;119(14):3361-9. PMID: 22234690.

 

Ye NS, Chen J, Luo GA, et al. Proteomic profiling of rat bone marrow mesenchymal stem cells induced by 5-azacytidine. Stem Cells ev. 2006 Oct;15(5):665-76. PMID: 17105402.

 

Bouchard J, Walker MC, Leclerc JM, et al. 5-azacytidine and 5-azadeoxycytidine inhibit human immunodeficiency virus type 1 replication in vitro. Antimicrob Agents Chemother. 1990 Feb;34(2):206-9. PMID: 1691617.

" T, Xn, Carc. Not dangerous goods.

LKT A9602 Azacitidine 1 g 305.9 Nucleoside (cytidine) analog; DNMT inhibitor, protein synthesis inhibitor. 4-amino-1-β-D-ribofuranosyl-1,3,5-triazin-2(1H)-one 320-67-2 ≥98% 244.2 C8H12N4O5 C1=NC(=NC(=O)N1C2C(C(C(O2)CO)O)O)N "The half-life of the 

compound in phosphate buffered saline, pH 7.4,when heated to 50°C is 90 minutes. Prepare fresh stock solution for each usage, and keep at 0°C until used." Ambient Ambient Soluble in water, but unstable. "Borodovsky A, Salmasi V, Turcan S, et al. 5-azacytidine reduces methylation, promotes differentiation and induces tumor regression in a patient-derived IDH1 mutant glioma xenograft. Oncotarget. 2013 Oct;4(10):1737-47. PMID: 24077805.

 

Solís-Paredes M, Eguía-Aguilar P, Chico-Ponce de León F, et al. Epigenetic modifications in cell lines of human astrocytoma differentially regulate expression of apoptotic genes. Childs Nerv Syst. 2013 Aug 13. Epub ahead of print. PMID: 23943192.

 

Tsujioka T, Yokoi A, Uesugi M, et al. Effects of DNA methyltransferase inhibitors (DNMTIs) on MDS-derived cell lines. Exp Hematol. 2013 Feb;41(2):189-97. PMID: 23085465.

 

Kimura S, Kuramoto K, Homan J, et al. Antiproliferative and antitumor effects of azacitidine against the human myelodysplastic syndrome cell line SKM-1. Anticancer Res. 2012 Mar;32(3):795-8. PMID: 22399596.

 

Goodyear OC, Dennis M, Jilani NY, et al. Azacitidine augments expansion of regulatory T cells after allogeneic stem cell transplantation in patients with acute myeloid leukemia (AML). Blood. 2012 Apr 5;119(14):3361-9. PMID: 22234690.

 

Ye NS, Chen J, Luo GA, et al. Proteomic profiling of rat bone marrow mesenchymal stem cells induced by 5-azacytidine. Stem Cells ev. 2006 Oct;15(5):665-76. PMID: 17105402.

 

Bouchard J, Walker MC, Leclerc JM, et al. 5-azacytidine and 5-azadeoxycytidine inhibit human immunodeficiency virus type 1 replication in vitro. Antimicrob Agents Chemother. 1990 Feb;34(2):206-9. PMID: 1691617.

" T, Xn, Carc. Not dangerous goods.

LKT A9603 5-Aza-2′-deoxycytidine 5 mg 50.2 Nucleoside (deoxycytidine) analog; DNMT inhibitor, protein synthesis inhibitor. 2'-Deoxy-5-azacytidine, 2353-33-5 ≥98% 228.21 C8H12N4O4 C1C(C(OC1N2C=NC(=NC2=O)N)CO)O Ambient Ambient acetic acid: water (1:1): 50 mg/mL "Zhou JH, Yao YS, Wang LX, et al. Demethylating agent decitabine induces autologous cancer testis antigen specific cytotoxic T lymphocytes in vivo. Chin Med J (Engl). 2013 Dec;126(23):4552-6. PMID: 24286424.

 

Wang Y, Wang X, Li R, et al. A DNA methyltransferase inhibitor, 5-aza-2'-deoxycytidine, exacerbates neurotoxicity and upregulates Parkinson's disease-related genes in dopaminergic neurons. CNS Neurosci Ther. 2013 Mar;19(3):183-90. PMID: 23441691.

 

Soncini M, Santoro F, Gutierrez A, et al. The DNA demethylating agent decitabine activates the TRAIL pathway and induces apoptosis in acute myeloid leukemia. Biochim Biophys Acta. 2013 Jan;1832(1):114-20. PMID: 23046813.

 

Datta J, Ghoshal K, Motiwala T, et al. Novel Insights into the Molecular Mechanism of Action of DNA Hypomethylating Agents: Role of Protein Kinase C δ in Decitabine-Induced Degradation of DNA Methyltransferase 1. Genes Cancer. 2012 Jan;3(1):71-81. PMID: 22893792.

 

Saba HI. Decitabine in the treatment of myelodysplastic syndromes. Ther Clin Risk Manag. 2007 Oct;3(5):807-17. PMID: 18473005.

 

Momparler RL. Pharmacology of 5-Aza-2'-deoxycytidine (decitabine). Semin Hematol. 2005 Jul;42(3 Suppl 2):S9-16. PMID: 16015507.

 

Bouchard J, Walker MC, Leclerc JM, et al. 5-azacytidine and 5-azadeoxycytidine inhibit human immunodeficiency virus type 1 replication in vitro. Antimicrob Agents Chemother. 1990 Feb;34(2):206-9. PMID: 1691617." Xi, Xn Not dangerous goods.

LKT A9603 5-Aza-2′-deoxycytidine 10 mg 95.1 Nucleoside (deoxycytidine) analog; DNMT inhibitor, protein synthesis inhibitor. 2'-Deoxy-5-azacytidine, 2353-33-5 ≥98% 228.21 C8H12N4O4 C1C(C(OC1N2C=NC(=NC2=O)N)CO)O Ambient Ambient acetic acid: water (1:1): 50 mg/mL "Zhou JH, Yao YS, Wang LX, et al. Demethylating agent decitabine induces autologous cancer testis antigen specific cytotoxic T lymphocytes in vivo. Chin Med J (Engl). 2013 Dec;126(23):4552-6. PMID: 24286424.

 

Wang Y, Wang X, Li R, et al. A DNA methyltransferase inhibitor, 5-aza-2'-deoxycytidine, exacerbates neurotoxicity and upregulates Parkinson's disease-related genes in dopaminergic neurons. CNS Neurosci Ther. 2013 Mar;19(3):183-90. PMID: 23441691.

 

Soncini M, Santoro F, Gutierrez A, et al. The DNA demethylating agent decitabine activates the TRAIL pathway and induces apoptosis in acute myeloid leukemia. Biochim Biophys Acta. 2013 Jan;1832(1):114-20. PMID: 23046813.

 

Datta J, Ghoshal K, Motiwala T, et al. Novel Insights into the Molecular Mechanism of Action of DNA Hypomethylating Agents: Role of Protein Kinase C δ in Decitabine-Induced Degradation of DNA Methyltransferase 1. Genes Cancer. 2012 Jan;3(1):71-81. PMID: 22893792.

 

Saba HI. Decitabine in the treatment of myelodysplastic syndromes. Ther Clin Risk Manag. 2007 Oct;3(5):807-17. PMID: 18473005.

 

Momparler RL. Pharmacology of 5-Aza-2'-deoxycytidine (decitabine). Semin Hematol. 2005 Jul;42(3 Suppl 2):S9-16. PMID: 16015507.

 

Bouchard J, Walker MC, Leclerc JM, et al. 5-azacytidine and 5-azadeoxycytidine inhibit human immunodeficiency virus type 1 replication in vitro. Antimicrob Agents Chemother. 1990 Feb;34(2):206-9. PMID: 1691617." Xi, Xn Not dangerous goods.

LKT A9603 5-Aza-2′-deoxycytidine 50 mg 400.9 Nucleoside (deoxycytidine) analog; DNMT inhibitor, protein synthesis inhibitor. 2'-Deoxy-5-azacytidine, 2353-33-5 ≥98% 228.21 C8H12N4O4 C1C(C(OC1N2C=NC(=NC2=O)N)CO)O Ambient Ambient acetic acid: water (1:1): 50 mg/mL "Zhou JH, Yao YS, Wang LX, et al. Demethylating agent decitabine induces autologous cancer testis antigen specific cytotoxic T lymphocytes in vivo. Chin Med J (Engl). 2013 Dec;126(23):4552-6. PMID: 24286424.

 

Wang Y, Wang X, Li R, et al. A DNA methyltransferase inhibitor, 5-aza-2'-deoxycytidine, exacerbates neurotoxicity and upregulates Parkinson's disease-related genes in dopaminergic neurons. CNS Neurosci Ther. 2013 Mar;19(3):183-90. PMID: 23441691.

 

Soncini M, Santoro F, Gutierrez A, et al. The DNA demethylating agent decitabine activates the TRAIL pathway and induces apoptosis in acute myeloid leukemia. Biochim Biophys Acta. 2013 Jan;1832(1):114-20. PMID: 23046813.

 

Datta J, Ghoshal K, Motiwala T, et al. Novel Insights into the Molecular Mechanism of Action of DNA Hypomethylating Agents: Role of Protein Kinase C δ in Decitabine-Induced Degradation of DNA Methyltransferase 1. Genes Cancer. 2012 Jan;3(1):71-81. PMID: 22893792.

 

Saba HI. Decitabine in the treatment of myelodysplastic syndromes. Ther Clin Risk Manag. 2007 Oct;3(5):807-17. PMID: 18473005.

 

Momparler RL. Pharmacology of 5-Aza-2'-deoxycytidine (decitabine). Semin Hematol. 2005 Jul;42(3 Suppl 2):S9-16. PMID: 16015507.

 

Bouchard J, Walker MC, Leclerc JM, et al. 5-azacytidine and 5-azadeoxycytidine inhibit human immunodeficiency virus type 1 replication in vitro. Antimicrob Agents Chemother. 1990 Feb;34(2):206-9. PMID: 1691617." Xi, Xn Not dangerous goods.

LKT A9801 Azaperone 500 mg 173.3 Butyrophenone; α-adrenergic, D2, histamine antagonist. 1-(4-Fluorophenyl)-4-[4-(2-pyridinyl)-1-piperazinyl]-1 -butanone Stresnil; Suicalm 1649-18-9 ≥98% 327.4 C19H22FN3O C1CN(CCN1CCCC(=O)C2=CC=C(C=C2)F)C3=CC=CC=N3 Ambient 4°C Soluble in chloroform and ethyl acetate. "Wolfe LL, Fisher MC, Davis TR, et al. Efficacy of a Low-Dosage Combination of Butorphanol, Azaperone, and Medetomidine (BAM) to Immobilize Rocky Mountain Elk. J Wildl Dis. 2014 Jul;50(3):676-80. PMID: 24807358.

 

McCormick AV, Wheeler JM, Guthrie CR, et al. Dopamine D2 receptor antagonism suppresses tau aggregation and neurotoxicity. Biol Psychiatry. 2013 Mar 1;73(5):464-71. PMID: 23140663.

 

Mentaberre G, López-Olvera JR, Casas-Díaz E, et al. Use of haloperidol and azaperone for stress control in roe deer (Capreolus capreolus) captured by means of drive-nets. Res Vet Sci. 2010 Jun;88(3):531-5. PMID: 20006891.

 

Leysen JE, Gommeren W. The dissociation rate of unlabelled dopamine antagonists and agonists from the dopamine-D2 receptor, application of an original filter method. J Recept Res. 1984;4(7):817-45. PMID: 6527363.

" Xn "UN number: 2811     Class: 6.1     Packing Group: III

Proper shipping name: Toxic solid, organic, n.o.s. (Azaperone)"

LKT A9801 Azaperone 1 g 277.4 Butyrophenone; α-adrenergic, D2, histamine antagonist. 1-(4-Fluorophenyl)-4-[4-(2-pyridinyl)-1-piperazinyl]-1 -butanone Stresnil; Suicalm 1649-18-9 ≥98% 327.4 C19H22FN3O C1CN(CCN1CCCC(=O)C2=CC=C(C=C2)F)C3=CC=CC=N3 Ambient 4°C Soluble in chloroform and ethyl acetate. "Wolfe LL, Fisher MC, Davis TR, et al. Efficacy of a Low-Dosage Combination of Butorphanol, Azaperone, and Medetomidine (BAM) to Immobilize Rocky Mountain Elk. J Wildl Dis. 2014 Jul;50(3):676-80. PMID: 24807358.

 

McCormick AV, Wheeler JM, Guthrie CR, et al. Dopamine D2 receptor antagonism suppresses tau aggregation and neurotoxicity. Biol Psychiatry. 2013 Mar 1;73(5):464-71. PMID: 23140663.

 

Mentaberre G, López-Olvera JR, Casas-Díaz E, et al. Use of haloperidol and azaperone for stress control in roe deer (Capreolus capreolus) captured by means of drive-nets. Res Vet Sci. 2010 Jun;88(3):531-5. PMID: 20006891.

 

Leysen JE, Gommeren W. The dissociation rate of unlabelled dopamine antagonists and agonists from the dopamine-D2 receptor, application of an original filter method. J Recept Res. 1984;4(7):817-45. PMID: 6527363.

" Xn "UN number: 2811     Class: 6.1     Packing Group: III

Proper shipping name: Toxic solid, organic, n.o.s. (Azaperone)"

LKT A9801 Azaperone 5 g 1109 Butyrophenone; α-adrenergic, D2, histamine antagonist. 1-(4-Fluorophenyl)-4-[4-(2-pyridinyl)-1-piperazinyl]-1 -butanone Stresnil; Suicalm 1649-18-9 ≥98% 327.4 C19H22FN3O C1CN(CCN1CCCC(=O)C2=CC=C(C=C2)F)C3=CC=CC=N3 Ambient 4°C Soluble in chloroform and ethyl acetate. "Wolfe LL, Fisher MC, Davis TR, et al. Efficacy of a Low-Dosage Combination of Butorphanol, Azaperone, and Medetomidine (BAM) to Immobilize Rocky Mountain Elk. J Wildl Dis. 2014 Jul;50(3):676-80. PMID: 24807358.

 

McCormick AV, Wheeler JM, Guthrie CR, et al. Dopamine D2 receptor antagonism suppresses tau aggregation and neurotoxicity. Biol Psychiatry. 2013 Mar 1;73(5):464-71. PMID: 23140663.

 

Mentaberre G, López-Olvera JR, Casas-Díaz E, et al. Use of haloperidol and azaperone for stress control in roe deer (Capreolus capreolus) captured by means of drive-nets. Res Vet Sci. 2010 Jun;88(3):531-5. PMID: 20006891.

 

Leysen JE, Gommeren W. The dissociation rate of unlabelled dopamine antagonists and agonists from the dopamine-D2 receptor, application of an original filter method. J Recept Res. 1984;4(7):817-45. PMID: 6527363.

" Xn "UN number: 2811     Class: 6.1     Packing Group: III

Proper shipping name: Toxic solid, organic, n.o.s. (Azaperone)"

LKT A9803 Azathioprine 1 g 75 Purine nucleotide analog, mercaptiopurine prodrug; potential PRPP transferase and HGPRT inhibitor. 6-((1-methyl-4-nitroimidazol-5-yl)thio)purine; 6-((1-Methyl-4-nitro-1H-imidazol-5-yl)thio)purine; Imuran; Imurek; Imurel; Methylnitroimidazolylmercaptopurine AZA 446-86-6 ≥98% 277.26 C9H7N7O2S CN1C=NC(=C1SC2=NC=NC3=C2NC=N3)[N+](=O)[O-] Ambient Ambient Insoluble in water, slightly soluble in ethanol, soluble in DMSO. "Hernández-Breijo B, Monserrat J, Ramírez-Rubio S, et al. Preclinical evaluation of azathioprine plus buthionine sulfoximine in the treatment of human hepatocarcinoma and colon carcinoma. World J Gastroenterol. 2011 Sep 14;17(34):3899-911. PMID: 22025878.

 

Hoover S, Striker R. Thiopurines inhibit bovine viral diarrhea virus production in a thiopurine methyltransferase-dependent manner. J Gen Virol. 2008 Apr;89(Pt 4):1000-9. PMID: 18343842.

 

Poppe D, Tiede I, Fritz G, et al. Azathioprine suppresses ezrin-radixin-moesin-dependent T cell-APC conjugation through inhibition of Vav guanosine exchange activity on Rac proteins. J Immunol. 2006 Jan 1;176(1):640-51. PMID: 16365460.

 

Fuchs S, Bartfeld D, Eshhar Z, et al. Immune regulation of experimental myasthenia. J Neurol Neurosurg Psychiatry. 1980 Jul;43(7):634-43. PMID: 7400824.

" Carc., Xn,  Xi Not dangerous goods.

LKT A9803 Azathioprine 5 g 281.2 Purine nucleotide analog, mercaptiopurine prodrug; potential PRPP transferase and HGPRT inhibitor. 6-((1-methyl-4-nitroimidazol-5-yl)thio)purine; 6-((1-Methyl-4-nitro-1H-imidazol-5-yl)thio)purine; Imuran; Imurek; Imurel; Methylnitroimidazolylmercaptopurine AZA 446-86-6 ≥98% 277.26 C9H7N7O2S CN1C=NC(=C1SC2=NC=NC3=C2NC=N3)[N+](=O)[O-] Ambient Ambient Insoluble in water, slightly soluble in ethanol, soluble in DMSO. "Hernández-Breijo B, Monserrat J, Ramírez-Rubio S, et al. Preclinical evaluation of azathioprine plus buthionine sulfoximine in the treatment of human hepatocarcinoma and colon carcinoma. World J Gastroenterol. 2011 Sep 14;17(34):3899-911. PMID: 22025878.

 

Hoover S, Striker R. Thiopurines inhibit bovine viral diarrhea virus production in a thiopurine methyltransferase-dependent manner. J Gen Virol. 2008 Apr;89(Pt 4):1000-9. PMID: 18343842.

 

Poppe D, Tiede I, Fritz G, et al. Azathioprine suppresses ezrin-radixin-moesin-dependent T cell-APC conjugation through inhibition of Vav guanosine exchange activity on Rac proteins. J Immunol. 2006 Jan 1;176(1):640-51. PMID: 16365460.

 

Fuchs S, Bartfeld D, Eshhar Z, et al. Immune regulation of experimental myasthenia. J Neurol Neurosurg Psychiatry. 1980 Jul;43(7):634-43. PMID: 7400824.

" Carc., Xn,  Xi Not dangerous goods.

LKT A9803 Azathioprine 10 g 468.8 Purine nucleotide analog, mercaptiopurine prodrug; potential PRPP transferase and HGPRT inhibitor. 6-((1-methyl-4-nitroimidazol-5-yl)thio)purine; 6-((1-Methyl-4-nitro-1H-imidazol-5-yl)thio)purine; Imuran; Imurek; Imurel; Methylnitroimidazolylmercaptopurine AZA 446-86-6 ≥98% 277.26 C9H7N7O2S CN1C=NC(=C1SC2=NC=NC3=C2NC=N3)[N+](=O)[O-] Ambient Ambient Insoluble in water, slightly soluble in ethanol, soluble in DMSO. "Hernández-Breijo B, Monserrat J, Ramírez-Rubio S, et al. Preclinical evaluation of azathioprine plus buthionine sulfoximine in the treatment of human hepatocarcinoma and colon carcinoma. World J Gastroenterol. 2011 Sep 14;17(34):3899-911. PMID: 22025878.

 

Hoover S, Striker R. Thiopurines inhibit bovine viral diarrhea virus production in a thiopurine methyltransferase-dependent manner. J Gen Virol. 2008 Apr;89(Pt 4):1000-9. PMID: 18343842.

 

Poppe D, Tiede I, Fritz G, et al. Azathioprine suppresses ezrin-radixin-moesin-dependent T cell-APC conjugation through inhibition of Vav guanosine exchange activity on Rac proteins. J Immunol. 2006 Jan 1;176(1):640-51. PMID: 16365460.

 

Fuchs S, Bartfeld D, Eshhar Z, et al. Immune regulation of experimental myasthenia. J Neurol Neurosurg Psychiatry. 1980 Jul;43(7):634-43. PMID: 7400824.

" Carc., Xn,  Xi Not dangerous goods.

LKT A9817 Azelaic Acid 5 g 27.2 Dicarboxylic acid found in Arabidopsis; PPARγ agonist, KLK5 inhibitor. Nonanedioic acid 1,7-heptanedicarboxylic acid; Anchoic acid; Azelex 123-99-9 ≥98% 188.22 C9H16O4 C(CCCC(=O)O)CCCC(=O)O Ambient Ambient Soluble in boiling water and alcohol "Coda AB, Hata T, Miller J, et al. Cathelicidin, kallikrein 5, and serine protease activity is inhibited during treatment of rosacea with azelaic acid 15% gel. J Am Acad Dermatol. 2013 Oct;69(4):570-7. PMID: 23871720.

 

Briganti S, Flori E, Mastrofrancesco A, et al. Azelaic acid reduced senescence-like phenotype in photo-irradiated human dermal fibroblasts: possible implication of PPARγ. Exp Dermatol. 2013 Jan;22(1):41-7. PMID: 23278893.

 

Fitton A, Goa KL. Azelaic acid. A review of its pharmacological properties and therapeutic efficacy in acne and hyperpigmentary skin disorders. Drugs. 1991 May;41(5):780-98. PMID: 1712709.

" None Not dangerous goods.

LKT A9817 Azelaic Acid 25 g 47.6 Dicarboxylic acid found in Arabidopsis; PPARγ agonist, KLK5 inhibitor. Nonanedioic acid 1,7-heptanedicarboxylic acid; Anchoic acid; Azelex 123-99-9 ≥98% 188.22 C9H16O4 C(CCCC(=O)O)CCCC(=O)O Ambient Ambient Soluble in boiling water and alcohol "Coda AB, Hata T, Miller J, et al. Cathelicidin, kallikrein 5, and serine protease activity is inhibited during treatment of rosacea with azelaic acid 15% gel. J Am Acad Dermatol. 2013 Oct;69(4):570-7. PMID: 23871720.

 

Briganti S, Flori E, Mastrofrancesco A, et al. Azelaic acid reduced senescence-like phenotype in photo-irradiated human dermal fibroblasts: possible implication of PPARγ. Exp Dermatol. 2013 Jan;22(1):41-7. PMID: 23278893.

 

Fitton A, Goa KL. Azelaic acid. A review of its pharmacological properties and therapeutic efficacy in acne and hyperpigmentary skin disorders. Drugs. 1991 May;41(5):780-98. PMID: 1712709.

" None Not dangerous goods.

LKT A9818 Azelastine Hydrochloride 100 mg 76.3 TRPV1 agonist, histamine H1 antagonist. 4-[(4-Chlorophenyl)methyl]-2-(hexahydro-1-methyl- 1H-azepin-4-yl)-1(2H)-phthalazinone hydrochloroide Allergodil; Astelin; Azeptin; Optilast; Rhinolast 79307-93-0 ≥98% 418.35 C22H24ClN3O CN1CCCC(CC1)N2C(=O)C3=CC=CC=C3C(=N2)CC4=CC=C(C=C4)Cl.Cl Ambient Ambient Slightly soluble in ethanol, octanol or glycerine. "Singh U, Bernstein JA, Haar L, et al. Azelastine desensitization of transient receptor potential vanilloid 1: A potential mechanism explaining its therapeutic effect in nonallergic rhinitis. Am J Rhinol Allergy. 2014 May;28(3):215-24. PMID: 24980233.

 

Horak F, Zieglmayer UP. Azelastine nasal spray for the treatment of allergic and nonallergic rhinitis. Expert Rev Clin Immunol. 2009 Nov;5(6):659-69. PMID: 20477689.

 

Kempuraj D, Huang M, Kandere-Grzybowska K, et al. Azelastine inhibits secretion of IL-6, TNF-alpha and IL-8 as well as NF-kappaB activation and intracellular calcium ion levels in normal human mast cells. Int Arch Allergy Immunol. 2003 Nov;132(3):231-9. PMID: 14646384.

 

Ito N, Shioya T, Watanabe A, et al. Mechanism of the antitussive effect of azelastine in guinea pigs. Arzneimittelforschung. 2002;52(6):441-7. PMID: 12109044.

" Xn Not dangerous goods.

LKT A9818 Azelastine Hydrochloride 500 mg 216.3 TRPV1 agonist, histamine H1 antagonist. 4-[(4-Chlorophenyl)methyl]-2-(hexahydro-1-methyl- 1H-azepin-4-yl)-1(2H)-phthalazinone hydrochloroide Allergodil; Astelin; Azeptin; Optilast; Rhinolast 79307-93-0 ≥98% 418.35 C22H24ClN3O CN1CCCC(CC1)N2C(=O)C3=CC=CC=C3C(=N2)CC4=CC=C(C=C4)Cl.Cl Ambient Ambient Slightly soluble in ethanol, octanol or glycerine. "Singh U, Bernstein JA, Haar L, et al. Azelastine desensitization of transient receptor potential vanilloid 1: A potential mechanism explaining its therapeutic effect in nonallergic rhinitis. Am J Rhinol Allergy. 2014 May;28(3):215-24. PMID: 24980233.

 

Horak F, Zieglmayer UP. Azelastine nasal spray for the treatment of allergic and nonallergic rhinitis. Expert Rev Clin Immunol. 2009 Nov;5(6):659-69. PMID: 20477689.

 

Kempuraj D, Huang M, Kandere-Grzybowska K, et al. Azelastine inhibits secretion of IL-6, TNF-alpha and IL-8 as well as NF-kappaB activation and intracellular calcium ion levels in normal human mast cells. Int Arch Allergy Immunol. 2003 Nov;132(3):231-9. PMID: 14646384.

 

Ito N, Shioya T, Watanabe A, et al. Mechanism of the antitussive effect of azelastine in guinea pigs. Arzneimittelforschung. 2002;52(6):441-7. PMID: 12109044.

" Xn Not dangerous goods.

LKT A9818 Azelastine Hydrochloride 1 g 343.4 TRPV1 agonist, histamine H1 antagonist. 4-[(4-Chlorophenyl)methyl]-2-(hexahydro-1-methyl- 1H-azepin-4-yl)-1(2H)-phthalazinone hydrochloroide Allergodil; Astelin; Azeptin; Optilast; Rhinolast 79307-93-0 ≥98% 418.35 C22H24ClN3O CN1CCCC(CC1)N2C(=O)C3=CC=CC=C3C(=N2)CC4=CC=C(C=C4)Cl.Cl Ambient Ambient Slightly soluble in ethanol, octanol or glycerine. "Singh U, Bernstein JA, Haar L, et al. Azelastine desensitization of transient receptor potential vanilloid 1: A potential mechanism explaining its therapeutic effect in nonallergic rhinitis. Am J Rhinol Allergy. 2014 May;28(3):215-24. PMID: 24980233.

 

Horak F, Zieglmayer UP. Azelastine nasal spray for the treatment of allergic and nonallergic rhinitis. Expert Rev Clin Immunol. 2009 Nov;5(6):659-69. PMID: 20477689.

 

Kempuraj D, Huang M, Kandere-Grzybowska K, et al. Azelastine inhibits secretion of IL-6, TNF-alpha and IL-8 as well as NF-kappaB activation and intracellular calcium ion levels in normal human mast cells. Int Arch Allergy Immunol. 2003 Nov;132(3):231-9. PMID: 14646384.

 

Ito N, Shioya T, Watanabe A, et al. Mechanism of the antitussive effect of azelastine in guinea pigs. Arzneimittelforschung. 2002;52(6):441-7. PMID: 12109044.

" Xn Not dangerous goods.

LKT A9834 Azithromycin Dihydrate 500 mg 54.4 Azalide macrolide; protein translation inhibitor. [2R-(2R*,3S*,4R*,5R*,8R*,10R*,11R*,12S*,13S*,- 14R*)]-13-[(2,6-Dideoxy-3-C-methyl-3-O-methyl-α- L-ribo-hexopyranosyl)oxy]-2-ethyl-3,4,10-trihydroxy-3,5,6,8,10,12,14-heptamethyl-11-[[3,4,6-trideoxy-3- (dimethylamio)-β-D-xylo-hexopyranosyl]oxy]-1-oxa- 6-azacyclopentadecan-15-one Azitrocin; Ribotrex; Sumamed; Zithromax; Zitromax 117772-70-0 ≥98% 785.02 C38H72N2O12 2H2O CCC1C(C(C(N(CC(CC(C(C(C(C(C(=O)O1)C)OC2CC(C(C(O2)C)O)(C)OC)C)OC3C(C(CC(O3)C)N(C)C)O)(C)O)C)C)C)O)(C)O Ambient Ambient Slightly soluble in water. DMSO:100mg/mL, Ethanol:100mg/mL "Bakheit AH, Al-Hadiya BM, Abd-Elgalil AA. Azithromycin. Profiles Drug Subst Excip Relat Methodol. 2014;39:1-40. PMID: 24794904.

 

Medina CA, Rowe AM, Yun H, et al. Azithromycin treatment increases survival of high-risk corneal allotransplants. Cornea. 2013 May;32(5):658-66. PMID: 23407315.

 

Banerjee B, Musk M, Sutanto EN, et al. Regional differences in susceptibiity of bronchial epithelium to mesenchymal transition and inhibition by the macrolide antibiotic azithromycin. PLoS One. 2012;7(12):e52309. PMID: 23284981.

 

Banjanac M, Munić Kos V, Nujić K, et al. Anti-inflammatory mechanism of action of azithromycin in LPS-stimulated J774A.1 cells. Pharmacol Res. 2012 Oct;66(4):357-62. PMID: 22766077.

 

Togami K, Chono S, Morimoto K. Distribution characteristics of clarithromycin and azithromycin, macrolide antimicrobial agents used for treatment of respiratory infections, in lung epithelial lining fluid and alveolar macrophages. Biopharm Drug Dispos. 2011 Oct;32(7):389-397. PMID: 21812004.

" Xn Not dangerous goods.

LKT A9834 Azithromycin Dihydrate 1 g 95.1 Azalide macrolide; protein translation inhibitor. [2R-(2R*,3S*,4R*,5R*,8R*,10R*,11R*,12S*,13S*,- 14R*)]-13-[(2,6-Dideoxy-3-C-methyl-3-O-methyl-α- L-ribo-hexopyranosyl)oxy]-2-ethyl-3,4,10-trihydroxy-3,5,6,8,10,12,14-heptamethyl-11-[[3,4,6-trideoxy-3- (dimethylamio)-β-D-xylo-hexopyranosyl]oxy]-1-oxa- 6-azacyclopentadecan-15-one Azitrocin; Ribotrex; Sumamed; Zithromax; Zitromax 117772-70-0 ≥98% 785.02 C38H72N2O12 2H2O CCC1C(C(C(N(CC(CC(C(C(C(C(C(=O)O1)C)OC2CC(C(C(O2)C)O)(C)OC)C)OC3C(C(CC(O3)C)N(C)C)O)(C)O)C)C)C)O)(C)O Ambient Ambient Slightly soluble in water. DMSO:100mg/mL, Ethanol:100mg/mL "Bakheit AH, Al-Hadiya BM, Abd-Elgalil AA. Azithromycin. Profiles Drug Subst Excip Relat Methodol. 2014;39:1-40. PMID: 24794904.

 

Medina CA, Rowe AM, Yun H, et al. Azithromycin treatment increases survival of high-risk corneal allotransplants. Cornea. 2013 May;32(5):658-66. PMID: 23407315.

 

Banerjee B, Musk M, Sutanto EN, et al. Regional differences in susceptibiity of bronchial epithelium to mesenchymal transition and inhibition by the macrolide antibiotic azithromycin. PLoS One. 2012;7(12):e52309. PMID: 23284981.

 

Banjanac M, Munić Kos V, Nujić K, et al. Anti-inflammatory mechanism of action of azithromycin in LPS-stimulated J774A.1 cells. Pharmacol Res. 2012 Oct;66(4):357-62. PMID: 22766077.

 

Togami K, Chono S, Morimoto K. Distribution characteristics of clarithromycin and azithromycin, macrolide antimicrobial agents used for treatment of respiratory infections, in lung epithelial lining fluid and alveolar macrophages. Biopharm Drug Dispos. 2011 Oct;32(7):389-397. PMID: 21812004.

" Xn Not dangerous goods.

LKT A9834 Azithromycin Dihydrate 5 g 339.8 Azalide macrolide; protein translation inhibitor. [2R-(2R*,3S*,4R*,5R*,8R*,10R*,11R*,12S*,13S*,- 14R*)]-13-[(2,6-Dideoxy-3-C-methyl-3-O-methyl-α- L-ribo-hexopyranosyl)oxy]-2-ethyl-3,4,10-trihydroxy-3,5,6,8,10,12,14-heptamethyl-11-[[3,4,6-trideoxy-3- (dimethylamio)-β-D-xylo-hexopyranosyl]oxy]-1-oxa- 6-azacyclopentadecan-15-one Azitrocin; Ribotrex; Sumamed; Zithromax; Zitromax 117772-70-0 ≥98% 785.02 C38H72N2O12 2H2O CCC1C(C(C(N(CC(CC(C(C(C(C(C(=O)O1)C)OC2CC(C(C(O2)C)O)(C)OC)C)OC3C(C(CC(O3)C)N(C)C)O)(C)O)C)C)C)O)(C)O Ambient Ambient Slightly soluble in water. DMSO:100mg/mL, Ethanol:100mg/mL "Bakheit AH, Al-Hadiya BM, Abd-Elgalil AA. Azithromycin. Profiles Drug Subst Excip Relat Methodol. 2014;39:1-40. PMID: 24794904.

 

Medina CA, Rowe AM, Yun H, et al. Azithromycin treatment increases survival of high-risk corneal allotransplants. Cornea. 2013 May;32(5):658-66. PMID: 23407315.

 

Banerjee B, Musk M, Sutanto EN, et al. Regional differences in susceptibiity of bronchial epithelium to mesenchymal transition and inhibition by the macrolide antibiotic azithromycin. PLoS One. 2012;7(12):e52309. PMID: 23284981.

 

Banjanac M, Munić Kos V, Nujić K, et al. Anti-inflammatory mechanism of action of azithromycin in LPS-stimulated J774A.1 cells. Pharmacol Res. 2012 Oct;66(4):357-62. PMID: 22766077.

 

Togami K, Chono S, Morimoto K. Distribution characteristics of clarithromycin and azithromycin, macrolide antimicrobial agents used for treatment of respiratory infections, in lung epithelial lining fluid and alveolar macrophages. Biopharm Drug Dispos. 2011 Oct;32(7):389-397. PMID: 21812004.

" Xn Not dangerous goods.

LKT A9978 Aztreonam 10 mg 52.6 β-lactam; penicillin binding protein inhibitor. "2-(((1-(2-amino-4-thiazolyl)-2-((2-methyl-4-oxo-1 -sulfo-3-azetidinyl)amino)-2-oxoethylidene)amino)oxy)-2-methyl-, (2S-(2alpha,3beta(Z)))-Propanoic acid 

 

" Azthreonam; SQ-26776; Azactam; Primbactam. 78110-38-0 ≥96% 435.43 C13H17N5O8S2 CC1C(C(=O)N1S(=O)(=O)[O-])NC(=O)C(=NOC(C)(C)C(=O)O)C2=CSC(=N2)[NH3+] Ambient Ambient Soluble in DMSO or DMF. Dallal MM, Czachor JS. Aztreonam-induced myelosuppression during treatment of Pseudomonas aeruginosa pneumonia. DICP. 1991 Jun;25(6):594-7. PMID: 1877266. None Not dangerous goods.

LKT A9978 Aztreonam 50 mg 125.9 β-lactam; penicillin binding protein inhibitor. "2-(((1-(2-amino-4-thiazolyl)-2-((2-methyl-4-oxo-1 -sulfo-3-azetidinyl)amino)-2-oxoethylidene)amino)oxy)-2-methyl-, (2S-(2alpha,3beta(Z)))-Propanoic acid 

 

" Azthreonam; SQ-26776; Azactam; Primbactam. 78110-38-0 ≥96% 435.43 C13H17N5O8S2 CC1C(C(=O)N1S(=O)(=O)[O-])NC(=O)C(=NOC(C)(C)C(=O)O)C2=CSC(=N2)[NH3+] Ambient Ambient Soluble in DMSO or DMF. Dallal MM, Czachor JS. Aztreonam-induced myelosuppression during treatment of Pseudomonas aeruginosa pneumonia. DICP. 1991 Jun;25(6):594-7. PMID: 1877266. None Not dangerous goods.

LKT A9978 Aztreonam 250 mg 420.1 β-lactam; penicillin binding protein inhibitor. "2-(((1-(2-amino-4-thiazolyl)-2-((2-methyl-4-oxo-1 -sulfo-3-azetidinyl)amino)-2-oxoethylidene)amino)oxy)-2-methyl-, (2S-(2alpha,3beta(Z)))-Propanoic acid 

 

" Azthreonam; SQ-26776; Azactam; Primbactam. 78110-38-0 ≥96% 435.43 C13H17N5O8S2 CC1C(C(=O)N1S(=O)(=O)[O-])NC(=O)C(=NOC(C)(C)C(=O)O)C2=CSC(=N2)[NH3+] Ambient Ambient Soluble in DMSO or DMF. Dallal MM, Czachor JS. Aztreonam-induced myelosuppression during treatment of Pseudomonas aeruginosa pneumonia. DICP. 1991 Jun;25(6):594-7. PMID: 1877266. None Not dangerous goods.

LKT B0026 Bafilomycin B1 1 mg 254.8 Macrolide; vacuolar H+-ATPase inhibitor. "Hygrolidin,37-decarboxy-2-demethyl-37-(((2-hydroxy-5-oxo-1-cyclopenten-1-yl)amino)carbonyl)-2-methoxy-24-methyl- 

" Setamycin 88899-56-3 ≥97% 815.99 C44H65NO13 CC1CC(=CC=CC(C(OC(=O)C(=CC(=CC(C1O)C)C)OC)C(C)C(C(C)C2(CC(C(C(O2)C(C)C)C)OC(=O)C=CC(=O)NC3=C(CCC3=O)O)O)O)OC)C Ambient -20°C Soluble in methanol. "Schachtschabel D, Arentshorst M, Lagendijk EL, et al. Vacuolar H(+)-ATPase plays a key role in cell wall biosynthesis of Aspergillus niger. Fungal Genet Biol. 2012 Apr;49(4):284-93. PMID: 22222772.

 

Hettiarachchi KD, Zimmet PZ, Danial NN, et al. Transplacental exposure to the vacuolar-ATPase inhibitor bafilomycin disrupts survival signaling in beta cells and delays neonatal remodeling of the endocrine pancreas. Exp Toxicol Pathol. 2008 Aug;60(4-5):295-306. PMID: 18486461.

" T+ "UN number: 3462     Class: 6.1     Packing Group: II

Proper shipping name: Toxins, extracted from living sources, solid, n.o.s. (Bafilomycin B1)"

LKT B0072 2B-(S) 1 mg 192.3 Peptide-biotin conjugate. ≥95% 1983.23 C81H137N28O28S Ambient -20°C

LKT B0072 2B-(S) 2 mg 327.1 Peptide-biotin conjugate. ≥95% 1983.23 C81H137N28O28S Ambient -20°C

LKT B0072 2B-(S) 5 mg 576.1 Peptide-biotin conjugate. ≥95% 1983.23 C81H137N28O28S Ambient -20°C

LKT B0108 Bactenecin 0.5 mg 324 Cathelicidin derivative, antimicrobial peptide, alters bacterial membrane permeability. Arg-leu-cyclo(cys-arg-ile-val-val-ile-arg-val-cys)-arg; Bac7  116229-36-8 ≥95% 1483.9 C63H118N24O13S2 CCC(C)C1C(=O)NC(C(=O)NC(C(=O)NC(C(=O)NC(C(=O)NC(C(=O)NC(CSSCC(C(=O)NC(C(=O)N1)CCCN=C(N)N)NC(=O)C(CC(C)C)NC(=O)C(CCCN=C(N)N)N)C(=O)NC(CCCN=C(N)N)C(=O)O)C(C)C)CCCN=C(N)N)C(C)CC)C(C)C)C(C)C Ambient -20°C "Madhongsa K, Pasan S, Phophetleb O, et al. Antimicrobial action of the cyclic peptide bactenecin on Burkholderia pseudomallei correlates with efficient membrane permeabilization. PLoS Negl Trop Dis. 2013 Jun 13;7(6):e2267. PMID: 23785532.

 

Lee JY, Yang ST, Lee SK, et al. Salt-resistant homodimeric bactenecin, a cathelicidin-derived antimicrobial peptide. FEBS J. 2008 Aug;275(15):3911-20. PMID: 18616463.

 

Wu M, Hancock RE. Interaction of the cyclic antimicrobial cationic peptide bactenecin with the outer and cytoplasmic membrane. J Biol Chem. 1999 Jan 1;274(1):29-35. PMID: 9867806.

" Not dangerous goods.

LKT B0108 Bactenecin 1 mg 552 Cathelicidin derivative, antimicrobial peptide, alters bacterial membrane permeability. Arg-leu-cyclo(cys-arg-ile-val-val-ile-arg-val-cys)-arg; Bac7  116229-36-8 ≥95% 1483.9 C63H118N24O13S2 CCC(C)C1C(=O)NC(C(=O)NC(C(=O)NC(C(=O)NC(C(=O)NC(C(=O)NC(CSSCC(C(=O)NC(C(=O)N1)CCCN=C(N)N)NC(=O)C(CC(C)C)NC(=O)C(CCCN=C(N)N)N)C(=O)NC(CCCN=C(N)N)C(=O)O)C(C)C)CCCN=C(N)N)C(C)CC)C(C)C)C(C)C Ambient -20°C "Madhongsa K, Pasan S, Phophetleb O, et al. Antimicrobial action of the cyclic peptide bactenecin on Burkholderia pseudomallei correlates with efficient membrane permeabilization. PLoS Negl Trop Dis. 2013 Jun 13;7(6):e2267. PMID: 23785532.

 

Lee JY, Yang ST, Lee SK, et al. Salt-resistant homodimeric bactenecin, a cathelicidin-derived antimicrobial peptide. FEBS J. 2008 Aug;275(15):3911-20. PMID: 18616463.

 

Wu M, Hancock RE. Interaction of the cyclic antimicrobial cationic peptide bactenecin with the outer and cytoplasmic membrane. J Biol Chem. 1999 Jan 1;274(1):29-35. PMID: 9867806.

" Not dangerous goods.

LKT B0109 Bakuchiol 10 mg 150.7 Prenylated phenolic terpene found in various plant sources;  ERα agonist. Phenol,4-[(1E,3S)-3-ethenyl-3,7-dimethyl-1,6-octadien-1-yl] Bakuchiol(7CI); Phenol, 4-(3-ethenyl-3,7-dimethyl-1,6-octadienyl)-, [S-(E)]-; Phenol,4-[(1E,3S)-3-ethenyl-3,7-dimethyl-1,6-octadienyl]- (9CI); (+)-Bakuchiol;(S)-(+)-Bakuchiol; (S)-Bakuchiol; Drupanol; UP 256 10309-37-2 ≥98% 256.38 C18H24O CC(=CCCC(C)(C=C)C=CC1=CC=C(C=C1)O)C Ambient -20°C "Lim SH, Ha TY, Ahn J, et al. Estrogenic activities of Psoralea corylifolia L. seed extracts and main constituents. Phytomedicine. 2011 Mar 15;18(5):425-30. PMID: 21382704.

 

Choi SY, Lee S, Choi WH, et al. Isolation and anti-inflammatory activity of Bakuchiol from Ulmus davidiana var. japonica. J Med Food. 2010 Aug;13(4):1019-23. PMID: 20553183.

 

Park EJ, Zhao YZ, Kim YC, et al. Bakuchiol-induced caspase-3-dependent apoptosis occurs through c-Jun NH2-terminal kinase-mediated mitochondrial translocation of Bax in rat liver myofibroblasts. Eur J Pharmacol. 2007 Mar 22;559(2-3):115-23. PMID: 17292878.

 

Katsura H, Tsukiyama RI, Suzuki A, et al. In vitro antimicrobial activities of bakuchiol against oral microorganisms. Antimicrob Agents Chemother. 2001 Nov;45(11):3009-13. PMID: 11600349.

 

Krenisky JM, Luo J, Reed MJ, et al. Isolation and antihyperglycemic activity of bakuchiol from Otholobium pubescens (Fabaceae), a Peruvian medicinal plant used for the treatment of diabetes. Biol Pharm Bull. 1999 Oct;22(10):1137-40. PMID: 10549873.

 

Ferrándiz ML, Gil B, Sanz MJ, et al. Effect of bakuchiol on leukocyte functions and some inflammatory responses in mice. J Pharm Pharmacol. 1996 Sep;48(9):975-80. PMID: 8910867.

" Not dangerous goods

LKT B0109 Bakuchiol 25 mg 301.5 Prenylated phenolic terpene found in various plant sources;  ERα agonist. Phenol,4-[(1E,3S)-3-ethenyl-3,7-dimethyl-1,6-octadien-1-yl] Bakuchiol(7CI); Phenol, 4-(3-ethenyl-3,7-dimethyl-1,6-octadienyl)-, [S-(E)]-; Phenol,4-[(1E,3S)-3-ethenyl-3,7-dimethyl-1,6-octadienyl]- (9CI); (+)-Bakuchiol;(S)-(+)-Bakuchiol; (S)-Bakuchiol; Drupanol; UP 256 10309-37-2 ≥98% 256.38 C18H24O CC(=CCCC(C)(C=C)C=CC1=CC=C(C=C1)O)C Ambient -20°C "Lim SH, Ha TY, Ahn J, et al. Estrogenic activities of Psoralea corylifolia L. seed extracts and main constituents. Phytomedicine. 2011 Mar 15;18(5):425-30. PMID: 21382704.

 

Choi SY, Lee S, Choi WH, et al. Isolation and anti-inflammatory activity of Bakuchiol from Ulmus davidiana var. japonica. J Med Food. 2010 Aug;13(4):1019-23. PMID: 20553183.

 

Park EJ, Zhao YZ, Kim YC, et al. Bakuchiol-induced caspase-3-dependent apoptosis occurs through c-Jun NH2-terminal kinase-mediated mitochondrial translocation of Bax in rat liver myofibroblasts. Eur J Pharmacol. 2007 Mar 22;559(2-3):115-23. PMID: 17292878.

 

Katsura H, Tsukiyama RI, Suzuki A, et al. In vitro antimicrobial activities of bakuchiol against oral microorganisms. Antimicrob Agents Chemother. 2001 Nov;45(11):3009-13. PMID: 11600349.

 

Krenisky JM, Luo J, Reed MJ, et al. Isolation and antihyperglycemic activity of bakuchiol from Otholobium pubescens (Fabaceae), a Peruvian medicinal plant used for the treatment of diabetes. Biol Pharm Bull. 1999 Oct;22(10):1137-40. PMID: 10549873.

 

Ferrándiz ML, Gil B, Sanz MJ, et al. Effect of bakuchiol on leukocyte functions and some inflammatory responses in mice. J Pharm Pharmacol. 1996 Sep;48(9):975-80. PMID: 8910867.

" Not dangerous goods

LKT B0109 Bakuchiol 100 mg 971.1 Prenylated phenolic terpene found in various plant sources;  ERα agonist. Phenol,4-[(1E,3S)-3-ethenyl-3,7-dimethyl-1,6-octadien-1-yl] Bakuchiol(7CI); Phenol, 4-(3-ethenyl-3,7-dimethyl-1,6-octadienyl)-, [S-(E)]-; Phenol,4-[(1E,3S)-3-ethenyl-3,7-dimethyl-1,6-octadienyl]- (9CI); (+)-Bakuchiol;(S)-(+)-Bakuchiol; (S)-Bakuchiol; Drupanol; UP 256 10309-37-2 ≥98% 256.38 C18H24O CC(=CCCC(C)(C=C)C=CC1=CC=C(C=C1)O)C Ambient -20°C "Lim SH, Ha TY, Ahn J, et al. Estrogenic activities of Psoralea corylifolia L. seed extracts and main constituents. Phytomedicine. 2011 Mar 15;18(5):425-30. PMID: 21382704.

 

Choi SY, Lee S, Choi WH, et al. Isolation and anti-inflammatory activity of Bakuchiol from Ulmus davidiana var. japonica. J Med Food. 2010 Aug;13(4):1019-23. PMID: 20553183.

 

Park EJ, Zhao YZ, Kim YC, et al. Bakuchiol-induced caspase-3-dependent apoptosis occurs through c-Jun NH2-terminal kinase-mediated mitochondrial translocation of Bax in rat liver myofibroblasts. Eur J Pharmacol. 2007 Mar 22;559(2-3):115-23. PMID: 17292878.

 

Katsura H, Tsukiyama RI, Suzuki A, et al. In vitro antimicrobial activities of bakuchiol against oral microorganisms. Antimicrob Agents Chemother. 2001 Nov;45(11):3009-13. PMID: 11600349.

 

Krenisky JM, Luo J, Reed MJ, et al. Isolation and antihyperglycemic activity of bakuchiol from Otholobium pubescens (Fabaceae), a Peruvian medicinal plant used for the treatment of diabetes. Biol Pharm Bull. 1999 Oct;22(10):1137-40. PMID: 10549873.

 

Ferrándiz ML, Gil B, Sanz MJ, et al. Effect of bakuchiol on leukocyte functions and some inflammatory responses in mice. J Pharm Pharmacol. 1996 Sep;48(9):975-80. PMID: 8910867.

" Not dangerous goods

LKT B0110 Baclofen 1 g 40.7 GABA derivative; GABA-B agonist. β-(Aminomethyl)-4-chlorobenzenepropanoic acid Baclon; Clofen; Lioresal 1134-47-0 ≥98% 213.66 C10H12ClNO2 C1=CC(=CC=C1C(CC(=O)O)CN)Cl Ambient 4°C Soluble in water or NaOH. "Fukuhara K, Katafuchi T, Yoshimura M. Effects of baclofen on mechanical noxious and innocuous transmission in the spinal dorsal horn of the adult rat: in vivo patch-clamp analysis. Eur J Neurosci. 2013 Aug 20. [Epub ahead of print]. PMID: 23961926.

 

Kumru H, Kofler M, Flores MC, et al. Effect of intrathecal baclofen on evoked pain perception: an evoked potentials and quantitative thermal testing study. Eur J Pain. 2013 Aug;17(7):1039-47. PMID: 23239275.

 

Brennan JL, Leung JG, Gagliardi JP, et al. Clinical effectiveness of baclofen for the treatment of alcohol dependence: a review. Clin Pharmacol. 2013 Jul 3;5:99-107. PMID: 23869179.

 

Uchiyama T, Nakanishi K, Fukawa N, et al. Neuromodulation using intrathecal baclofen therapy for spasticity and dystonia. Neurol Med Chir (Tokyo). 2012;52(7):463-9. PMID: 22850493.

 

Miner P, Borkuhova Y, Shimonova L, et al. GABA-A and GABA-B receptors mediate feeding elicited by the GABA-B agonist baclofen in the ventral tegmental area and nucleus accumbens shell in rats: reciprocal and regional interactions. Brain Res. 2010 Oct 8;1355:86-96. PMID: 20696149.

 

Levy RA, Proudfit HK. The analgesic action of baclofen [beta-(4-chlorophenyl)-gamma-aminobutyric acid]. J Pharmacol Exp Ther. 1977 Aug;202(2):437-45. PMID: 886473.

" T "UN number: 2811     Class:  6.1     Packing group:  III

Proper shipping name:  Toxic solids, organic, n.o.s. (Baclofen)

Marine pollutant:  No     Poison inhalation hazard:  No"

LKT B0110 Baclofen 5 g 136 GABA derivative; GABA-B agonist. β-(Aminomethyl)-4-chlorobenzenepropanoic acid Baclon; Clofen; Lioresal 1134-47-0 ≥98% 213.66 C10H12ClNO2 C1=CC(=CC=C1C(CC(=O)O)CN)Cl Ambient 4°C Soluble in water or NaOH. "Fukuhara K, Katafuchi T, Yoshimura M. Effects of baclofen on mechanical noxious and innocuous transmission in the spinal dorsal horn of the adult rat: in vivo patch-clamp analysis. Eur J Neurosci. 2013 Aug 20. [Epub ahead of print]. PMID: 23961926.

 

Kumru H, Kofler M, Flores MC, et al. Effect of intrathecal baclofen on evoked pain perception: an evoked potentials and quantitative thermal testing study. Eur J Pain. 2013 Aug;17(7):1039-47. PMID: 23239275.

 

Brennan JL, Leung JG, Gagliardi JP, et al. Clinical effectiveness of baclofen for the treatment of alcohol dependence: a review. Clin Pharmacol. 2013 Jul 3;5:99-107. PMID: 23869179.

 

Uchiyama T, Nakanishi K, Fukawa N, et al. Neuromodulation using intrathecal baclofen therapy for spasticity and dystonia. Neurol Med Chir (Tokyo). 2012;52(7):463-9. PMID: 22850493.

 

Miner P, Borkuhova Y, Shimonova L, et al. GABA-A and GABA-B receptors mediate feeding elicited by the GABA-B agonist baclofen in the ventral tegmental area and nucleus accumbens shell in rats: reciprocal and regional interactions. Brain Res. 2010 Oct 8;1355:86-96. PMID: 20696149.

 

Levy RA, Proudfit HK. The analgesic action of baclofen [beta-(4-chlorophenyl)-gamma-aminobutyric acid]. J Pharmacol Exp Ther. 1977 Aug;202(2):437-45. PMID: 886473.

" T "UN number: 2811     Class:  6.1     Packing group:  III

Proper shipping name:  Toxic solids, organic, n.o.s. (Baclofen)

Marine pollutant:  No     Poison inhalation hazard:  No"

LKT B0110 Baclofen 10 g 224.3 GABA derivative; GABA-B agonist. β-(Aminomethyl)-4-chlorobenzenepropanoic acid Baclon; Clofen; Lioresal 1134-47-0 ≥98% 213.66 C10H12ClNO2 C1=CC(=CC=C1C(CC(=O)O)CN)Cl Ambient 4°C Soluble in water or NaOH. "Fukuhara K, Katafuchi T, Yoshimura M. Effects of baclofen on mechanical noxious and innocuous transmission in the spinal dorsal horn of the adult rat: in vivo patch-clamp analysis. Eur J Neurosci. 2013 Aug 20. [Epub ahead of print]. PMID: 23961926.

 

Kumru H, Kofler M, Flores MC, et al. Effect of intrathecal baclofen on evoked pain perception: an evoked potentials and quantitative thermal testing study. Eur J Pain. 2013 Aug;17(7):1039-47. PMID: 23239275.

 

Brennan JL, Leung JG, Gagliardi JP, et al. Clinical effectiveness of baclofen for the treatment of alcohol dependence: a review. Clin Pharmacol. 2013 Jul 3;5:99-107. PMID: 23869179.

 

Uchiyama T, Nakanishi K, Fukawa N, et al. Neuromodulation using intrathecal baclofen therapy for spasticity and dystonia. Neurol Med Chir (Tokyo). 2012;52(7):463-9. PMID: 22850493.

 

Miner P, Borkuhova Y, Shimonova L, et al. GABA-A and GABA-B receptors mediate feeding elicited by the GABA-B agonist baclofen in the ventral tegmental area and nucleus accumbens shell in rats: reciprocal and regional interactions. Brain Res. 2010 Oct 8;1355:86-96. PMID: 20696149.

 

Levy RA, Proudfit HK. The analgesic action of baclofen [beta-(4-chlorophenyl)-gamma-aminobutyric acid]. J Pharmacol Exp Ther. 1977 Aug;202(2):437-45. PMID: 886473.

" T "UN number: 2811     Class:  6.1     Packing group:  III

Proper shipping name:  Toxic solids, organic, n.o.s. (Baclofen)

Marine pollutant:  No     Poison inhalation hazard:  No"

LKT B0133 Baicalin 1 mg 30.3 Flavone found in Scutellaria; prolyl oligopeptidase and neuraminidase inhibitor 7-D-Glucuronic acid-5,6-dihydroxyflavone 21967-41-9 ≥95% 446.36 C21H18O11 C1=CC=C(C=C1)C2=CC(=O)C3=C(C(=C(C=C3O2)OC4C(C(C(C(O4)C(=O)O)O)O)O)O)O Ambient -20°C Soluble in DMSO or ethanol. "Ding Y, Dou J, Teng Z, et al. Antiviral activity of baicalin against influenza A (H1N1/H3N2) virus in cell culture and in mice and its inhibition of neuraminidase. Arch Virol. 2014 Jul 31. [Epub ahead of print]. PMID: 25078390.

 

Min W, Liu X, Qian Q, et al. The effects of baicalin against UVA-induced photoaging in skin fibroblasts. Am J Chin Med. 2014;42(3):709-27. PMID: 24871661.

 

Zhang L, Pu Z, Wang J, et al. Baicalin inhibits hypoxia-induced pulmonary artery smooth muscle cell proliferation via the AKT/HIF-1α/p27-associated pathway. Int J Mol Sci. 2014 May 9;15(5):8153-68. PMID: 24821539.

 

Zhou QB, Jin YL, Jia Q, et al. Baicalin attenuates brain edema in a rat model of intracerebral hemorrhage. Inflammation. 2014 Feb;37(1):107-15. PMID: 23974988.

 

Zheng J, Hu JD, Huang Y, et al. Effects of baicalin on HL-60 cell xenografts in nude mice and its mechanism. Zhongguo Shi Yan Xue Ye Xue Za Zhi. 2012 Oct;20(5):1066-71. PMID: 23114120.

 

Tarragó T, Kichik N, Claasen B, et al. Baicalin, a prodrug able to reach the CNS, is a prolyl oligopeptidase inhibitor. Bioorg Med Chem. 2008 Aug 1;16(15):7516-24. PMID: 18650094.

" Xi Not dangerous goods.

LKT B0133 Baicalin 5 mg 60.7 Flavone found in Scutellaria; prolyl oligopeptidase and neuraminidase inhibitor 7-D-Glucuronic acid-5,6-dihydroxyflavone 21967-41-9 ≥95% 446.36 C21H18O11 C1=CC=C(C=C1)C2=CC(=O)C3=C(C(=C(C=C3O2)OC4C(C(C(C(O4)C(=O)O)O)O)O)O)O Ambient -20°C Soluble in DMSO or ethanol. "Ding Y, Dou J, Teng Z, et al. Antiviral activity of baicalin against influenza A (H1N1/H3N2) virus in cell culture and in mice and its inhibition of neuraminidase. Arch Virol. 2014 Jul 31. [Epub ahead of print]. PMID: 25078390.

 

Min W, Liu X, Qian Q, et al. The effects of baicalin against UVA-induced photoaging in skin fibroblasts. Am J Chin Med. 2014;42(3):709-27. PMID: 24871661.

 

Zhang L, Pu Z, Wang J, et al. Baicalin inhibits hypoxia-induced pulmonary artery smooth muscle cell proliferation via the AKT/HIF-1α/p27-associated pathway. Int J Mol Sci. 2014 May 9;15(5):8153-68. PMID: 24821539.

 

Zhou QB, Jin YL, Jia Q, et al. Baicalin attenuates brain edema in a rat model of intracerebral hemorrhage. Inflammation. 2014 Feb;37(1):107-15. PMID: 23974988.

 

Zheng J, Hu JD, Huang Y, et al. Effects of baicalin on HL-60 cell xenografts in nude mice and its mechanism. Zhongguo Shi Yan Xue Ye Xue Za Zhi. 2012 Oct;20(5):1066-71. PMID: 23114120.

 

Tarragó T, Kichik N, Claasen B, et al. Baicalin, a prodrug able to reach the CNS, is a prolyl oligopeptidase inhibitor. Bioorg Med Chem. 2008 Aug 1;16(15):7516-24. PMID: 18650094.

" Xi Not dangerous goods.

LKT B0133 Baicalin 10 mg 95.1 Flavone found in Scutellaria; prolyl oligopeptidase and neuraminidase inhibitor 7-D-Glucuronic acid-5,6-dihydroxyflavone 21967-41-9 ≥95% 446.36 C21H18O11 C1=CC=C(C=C1)C2=CC(=O)C3=C(C(=C(C=C3O2)OC4C(C(C(C(O4)C(=O)O)O)O)O)O)O Ambient -20°C Soluble in DMSO or ethanol. "Ding Y, Dou J, Teng Z, et al. Antiviral activity of baicalin against influenza A (H1N1/H3N2) virus in cell culture and in mice and its inhibition of neuraminidase. Arch Virol. 2014 Jul 31. [Epub ahead of print]. PMID: 25078390.

 

Min W, Liu X, Qian Q, et al. The effects of baicalin against UVA-induced photoaging in skin fibroblasts. Am J Chin Med. 2014;42(3):709-27. PMID: 24871661.

 

Zhang L, Pu Z, Wang J, et al. Baicalin inhibits hypoxia-induced pulmonary artery smooth muscle cell proliferation via the AKT/HIF-1α/p27-associated pathway. Int J Mol Sci. 2014 May 9;15(5):8153-68. PMID: 24821539.

 

Zhou QB, Jin YL, Jia Q, et al. Baicalin attenuates brain edema in a rat model of intracerebral hemorrhage. Inflammation. 2014 Feb;37(1):107-15. PMID: 23974988.

 

Zheng J, Hu JD, Huang Y, et al. Effects of baicalin on HL-60 cell xenografts in nude mice and its mechanism. Zhongguo Shi Yan Xue Ye Xue Za Zhi. 2012 Oct;20(5):1066-71. PMID: 23114120.

 

Tarragó T, Kichik N, Claasen B, et al. Baicalin, a prodrug able to reach the CNS, is a prolyl oligopeptidase inhibitor. Bioorg Med Chem. 2008 Aug 1;16(15):7516-24. PMID: 18650094.

" Xi Not dangerous goods.

LKT B0150 Bambuterol Hydrochloride 500 mg 161.9 β2-adrenergic agonist, BChE inhibitor. Dimethylcarbamic acid 5-[2-[(1,1-dimethylethyl)- amino]-1-hydroxyethyl]-1,3-phenylene ester hydrochloride KWD-2183; Bambec 81732-46-9 ≥98% 403.91 C18H29N3O5 HCl CC(C)(C)NCC(C1=CC(=CC(=C1)OC(=O)N(C)C)OC(=O)N(C)C)O.Cl Ambient 4°C Soluble in water (33mg/mL). "Mohr F, Zimmermann M, Klein J. Mice heterozygous for AChE are more sensitive to AChE inhibitors but do not respond to BuChE inhibition. Neuropharmacology. 2013 Apr;67:37-45. PMID: 23147415.

 

Bosak A, Gazić I, Vinković V, et al. Stereoselective inhibition of human, mouse, and horse cholinesterases by bambuterol enantiomers. Chem Biol Interact. 2008 Sep 25;175(1-3):192-5. PMID: 18582854.

 

Waldeck B. Beta-adrenoceptor agonists and asthma--100 years of development. Eur J Pharmacol. 2002 Jun 7;445(1-2):1-12. PMID: 12065188.

" None Not dangerous goods.

LKT B0150 Bambuterol Hydrochloride 1 g 231.1 β2-adrenergic agonist, BChE inhibitor. Dimethylcarbamic acid 5-[2-[(1,1-dimethylethyl)- amino]-1-hydroxyethyl]-1,3-phenylene ester hydrochloride KWD-2183; Bambec 81732-46-9 ≥98% 403.91 C18H29N3O5 HCl CC(C)(C)NCC(C1=CC(=CC(=C1)OC(=O)N(C)C)OC(=O)N(C)C)O.Cl Ambient 4°C Soluble in water (33mg/mL). "Mohr F, Zimmermann M, Klein J. Mice heterozygous for AChE are more sensitive to AChE inhibitors but do not respond to BuChE inhibition. Neuropharmacology. 2013 Apr;67:37-45. PMID: 23147415.

 

Bosak A, Gazić I, Vinković V, et al. Stereoselective inhibition of human, mouse, and horse cholinesterases by bambuterol enantiomers. Chem Biol Interact. 2008 Sep 25;175(1-3):192-5. PMID: 18582854.

 

Waldeck B. Beta-adrenoceptor agonists and asthma--100 years of development. Eur J Pharmacol. 2002 Jun 7;445(1-2):1-12. PMID: 12065188.

" None Not dangerous goods.

LKT B0150 Bambuterol Hydrochloride 5 g 877.9 β2-adrenergic agonist, BChE inhibitor. Dimethylcarbamic acid 5-[2-[(1,1-dimethylethyl)- amino]-1-hydroxyethyl]-1,3-phenylene ester hydrochloride KWD-2183; Bambec 81732-46-9 ≥98% 403.91 C18H29N3O5 HCl CC(C)(C)NCC(C1=CC(=CC(=C1)OC(=O)N(C)C)OC(=O)N(C)C)O.Cl Ambient 4°C Soluble in water (33mg/mL). "Mohr F, Zimmermann M, Klein J. Mice heterozygous for AChE are more sensitive to AChE inhibitors but do not respond to BuChE inhibition. Neuropharmacology. 2013 Apr;67:37-45. PMID: 23147415.

 

Bosak A, Gazić I, Vinković V, et al. Stereoselective inhibition of human, mouse, and horse cholinesterases by bambuterol enantiomers. Chem Biol Interact. 2008 Sep 25;175(1-3):192-5. PMID: 18582854.

 

Waldeck B. Beta-adrenoceptor agonists and asthma--100 years of development. Eur J Pharmacol. 2002 Jun 7;445(1-2):1-12. PMID: 12065188.

" None Not dangerous goods.

LKT B1545 Benzalkonium Bromide 100 g 92.5 Quaternary ammonium cationic surfactant, dissociates bacterial lipid membranes. 91080-29-4 ≥96% C21H38BrN CCCCCCCCCCCC[N+](C)(C)CC1=CC=CC=C1.[Br-] Ambient Ambient "Larsen ST, Verder H, Nielsen GD. Airway effects of inhaled quaternary ammonium compounds in mice. Basic Clin Pharmacol Toxicol. 2012 Jun;110(6):537-43. PMID: 22188809.

 

Saito K, Hayakawa T, Kawabata R, et al. In vitro antibacterial and cytotoxicity assessments of an orthodontic bonding agent containing benzalkonium chloride. Angle Orthod. 2009 Mar;79(2):331-7. PMID: 19216609.

" Not dangerous goods.

LKT B1545 Benzalkonium Bromide 500 g 288.8 Quaternary ammonium cationic surfactant, dissociates bacterial lipid membranes. 91080-29-4 ≥96% C21H38BrN CCCCCCCCCCCC[N+](C)(C)CC1=CC=CC=C1.[Br-] Ambient Ambient "Larsen ST, Verder H, Nielsen GD. Airway effects of inhaled quaternary ammonium compounds in mice. Basic Clin Pharmacol Toxicol. 2012 Jun;110(6):537-43. PMID: 22188809.

 

Saito K, Hayakawa T, Kawabata R, et al. In vitro antibacterial and cytotoxicity assessments of an orthodontic bonding agent containing benzalkonium chloride. Angle Orthod. 2009 Mar;79(2):331-7. PMID: 19216609.

" Not dangerous goods.

LKT B1640 Benzydamine Hydrochloride 5 g 40.7 NSAID; PG synthetase inhibitor. N,N-Dimethyl-3-[[1-(phenylmethl)-1H-indazol-3-yl]oxy]-1-propanamine hydrochloride Benzindamine hydrochloride 132-69-4 ≥98% 345.87 C19H23N3O HCl CN(C)CCCOC1=NN(C2=CC=CC=C21)CC3=CC=CC=C3.Cl Ambient Ambient Soluble in water, ethanol, chloroform, n-butanol or DMSO "Chen CY, Kuo CJ, Lee YW, et al. Benzydamine hydrochloride on postoperative sore throat: a meta-analysis of randomized controlled trials. Can J Anaesth. 2014 Mar;61(3):220-8. PMID: 24263969.

 

Karavana Hizarcioğlu SY, Sezer B, Güneri P, et al. Efficacy of topical benzydamine hydrochloride gel on oral mucosal ulcers: an in vivo animal study. Int J Oral Maxillofac Surg. 2011 Sep;40(9):973-8. PMID: 21549562.

 

Fanaki NH, el-Nakeeb MA. Antimicrobial activity of benzydamine, a non-steroid anti-inflammatory agent. J Chemother. 1992 Dec;4(6):347-52. PMID: 1287137.

" Xn Not dangerous goods.

LKT B1640 Benzydamine Hydrochloride 25 g 169.9 NSAID; PG synthetase inhibitor. N,N-Dimethyl-3-[[1-(phenylmethl)-1H-indazol-3-yl]oxy]-1-propanamine hydrochloride Benzindamine hydrochloride 132-69-4 ≥98% 345.87 C19H23N3O HCl CN(C)CCCOC1=NN(C2=CC=CC=C21)CC3=CC=CC=C3.Cl Ambient Ambient Soluble in water, ethanol, chloroform, n-butanol or DMSO "Chen CY, Kuo CJ, Lee YW, et al. Benzydamine hydrochloride on postoperative sore throat: a meta-analysis of randomized controlled trials. Can J Anaesth. 2014 Mar;61(3):220-8. PMID: 24263969.

 

Karavana Hizarcioğlu SY, Sezer B, Güneri P, et al. Efficacy of topical benzydamine hydrochloride gel on oral mucosal ulcers: an in vivo animal study. Int J Oral Maxillofac Surg. 2011 Sep;40(9):973-8. PMID: 21549562.

 

Fanaki NH, el-Nakeeb MA. Antimicrobial activity of benzydamine, a non-steroid anti-inflammatory agent. J Chemother. 1992 Dec;4(6):347-52. PMID: 1287137.

" Xn Not dangerous goods.

LKT B1753 Benfotiamine 250 mg 56.3 Thiamine/vitamin B derivative, antioxidant. S-Benzoylthiamine O-monophosphate 22457-89-2 ≥98% 466.453 C19H23N4O6PS CC1=NC=C(C(=N1)N)CN(C=O)C(=C(CCOP(=O)(O)O)SC(=O)C2=CC=CC=C2)C Ambient Ambient "Hurt JK, Coleman JL, Fitzpatrick BJ, et al. Prostatic acid phosphatase is required for the antinociceptive effects of thiamine and benfotiamine. PLoS One. 2012;7(10):e48562. PMID: 23119057.

 

Sun XJ, Zhao L, Zhao N, et al. Benfotiamine prevents increased β-amyloid production in HEK cells induced by high glucose. Neurosci Bull. 2012 Oct;28(5):561-6. PMID: 22961478.

 

Shoeb M, Ramana KV. Anti-inflammatory effects of benfotiamine are mediated through the regulation of the arachidonic acid pathway in macrophages. Free Radic Biol Med. 2012 Jan 1;52(1):182-90. PMID: 22067901.

 

Wu S, Ren J. Benfotiamine alleviates diabetes-induced cerebral oxidative damage independent of advanced glycation end-product, tissue factor and TNF-alpha. Neurosci Lett. 2006 Feb 13;394(2):158-62. PMID: 16260089.

" Xn, Xi Not dangerous goods.

LKT B1753 Benfotiamine 1 g 112.5 Thiamine/vitamin B derivative, antioxidant. S-Benzoylthiamine O-monophosphate 22457-89-2 ≥98% 466.453 C19H23N4O6PS CC1=NC=C(C(=N1)N)CN(C=O)C(=C(CCOP(=O)(O)O)SC(=O)C2=CC=CC=C2)C Ambient Ambient "Hurt JK, Coleman JL, Fitzpatrick BJ, et al. Prostatic acid phosphatase is required for the antinociceptive effects of thiamine and benfotiamine. PLoS One. 2012;7(10):e48562. PMID: 23119057.

 

Sun XJ, Zhao L, Zhao N, et al. Benfotiamine prevents increased β-amyloid production in HEK cells induced by high glucose. Neurosci Bull. 2012 Oct;28(5):561-6. PMID: 22961478.

 

Shoeb M, Ramana KV. Anti-inflammatory effects of benfotiamine are mediated through the regulation of the arachidonic acid pathway in macrophages. Free Radic Biol Med. 2012 Jan 1;52(1):182-90. PMID: 22067901.

 

Wu S, Ren J. Benfotiamine alleviates diabetes-induced cerebral oxidative damage independent of advanced glycation end-product, tissue factor and TNF-alpha. Neurosci Lett. 2006 Feb 13;394(2):158-62. PMID: 16260089.

" Xn, Xi Not dangerous goods.

LKT B1753 Benfotiamine 5 g 234.5 Thiamine/vitamin B derivative, antioxidant. S-Benzoylthiamine O-monophosphate 22457-89-2 ≥98% 466.453 C19H23N4O6PS CC1=NC=C(C(=N1)N)CN(C=O)C(=C(CCOP(=O)(O)O)SC(=O)C2=CC=CC=C2)C Ambient Ambient "Hurt JK, Coleman JL, Fitzpatrick BJ, et al. Prostatic acid phosphatase is required for the antinociceptive effects of thiamine and benfotiamine. PLoS One. 2012;7(10):e48562. PMID: 23119057.

 

Sun XJ, Zhao L, Zhao N, et al. Benfotiamine prevents increased β-amyloid production in HEK cells induced by high glucose. Neurosci Bull. 2012 Oct;28(5):561-6. PMID: 22961478.

 

Shoeb M, Ramana KV. Anti-inflammatory effects of benfotiamine are mediated through the regulation of the arachidonic acid pathway in macrophages. Free Radic Biol Med. 2012 Jan 1;52(1):182-90. PMID: 22067901.

 

Wu S, Ren J. Benfotiamine alleviates diabetes-induced cerebral oxidative damage independent of advanced glycation end-product, tissue factor and TNF-alpha. Neurosci Lett. 2006 Feb 13;394(2):158-62. PMID: 16260089.

" Xn, Xi Not dangerous goods.

LKT B1769 Bergenin 1 mg 115.4 Trihydroxybenzoic acid glycoside found in Bergenia. 477-90-7 ≥98% 328.27 C14H16O9 H2O COC1=C(C=C2C(=C1O)C3C(C(C(C(O3)CO)O)O)OC2=O)O.O Ambient -20°C Soluble in water. "Jain SK, Singh S, Khajuria A, et al. Pyrano-isochromanones as IL-6 Inhibitors: Synthesis, in Vitro and in Vivo Antiarthritic Activity. J Med Chem. 2014 Aug 28;57(16):7085-97. PMID: 25111439.

 

Liang J, Li Y, Liu X, et al. In vivo and in vitro antimalarial activity of bergenin. Biomed Rep. 2014 Mar;2(2):260-264. PMID: 24649107.

 

Zhang J, Nishimoto Y, Tokuda H, et al. Cancer chemopreventive effect of bergenin from Peltophorum pterocarpum wood. Chem Biodivers. 2013 Oct;10(10):1866-75. PMID: 24130029.

 

Kumar R, Patel DK, Prasad SK, et al. Type 2 antidiabetic activity of bergenin from the roots of Caesalpinia digyna Rottler. Fitoterapia. 2012 Mar;83(2):395-401. PMID: 22178680.

 

de Oliveira CM, Nonato FR, de Lima FO, et al. Antinociceptive properties of bergenin. J Nat Prod. 2011 Oct 28;74(10):2062-8. Erratum in: J Nat Prod. 2012 Feb 24;75(2):305.  PMID: 21939182.

 

Wang X, Tang S, Zhai H, et al. Studies on anti-tumor metastatic constituents from Ardisia Crenata. Zhongguo Zhong Yao Za Zhi. 2011 Apr;36(7):881-5. PMID: 21761727.

" Xi Not dangerous goods.

LKT B1769 Bergenin 5 mg 418.3 Trihydroxybenzoic acid glycoside found in Bergenia. 477-90-7 ≥98% 328.27 C14H16O9 H2O COC1=C(C=C2C(=C1O)C3C(C(C(C(O3)CO)O)O)OC2=O)O.O Ambient -20°C Soluble in water. "Jain SK, Singh S, Khajuria A, et al. Pyrano-isochromanones as IL-6 Inhibitors: Synthesis, in Vitro and in Vivo Antiarthritic Activity. J Med Chem. 2014 Aug 28;57(16):7085-97. PMID: 25111439.

 

Liang J, Li Y, Liu X, et al. In vivo and in vitro antimalarial activity of bergenin. Biomed Rep. 2014 Mar;2(2):260-264. PMID: 24649107.

 

Zhang J, Nishimoto Y, Tokuda H, et al. Cancer chemopreventive effect of bergenin from Peltophorum pterocarpum wood. Chem Biodivers. 2013 Oct;10(10):1866-75. PMID: 24130029.

 

Kumar R, Patel DK, Prasad SK, et al. Type 2 antidiabetic activity of bergenin from the roots of Caesalpinia digyna Rottler. Fitoterapia. 2012 Mar;83(2):395-401. PMID: 22178680.

 

de Oliveira CM, Nonato FR, de Lima FO, et al. Antinociceptive properties of bergenin. J Nat Prod. 2011 Oct 28;74(10):2062-8. Erratum in: J Nat Prod. 2012 Feb 24;75(2):305.  PMID: 21939182.

 

Wang X, Tang S, Zhai H, et al. Studies on anti-tumor metastatic constituents from Ardisia Crenata. Zhongguo Zhong Yao Za Zhi. 2011 Apr;36(7):881-5. PMID: 21761727.

" Xi Not dangerous goods.

LKT B1769 Bergenin 10 mg 610.9 Trihydroxybenzoic acid glycoside found in Bergenia. 477-90-7 ≥98% 328.27 C14H16O9 H2O COC1=C(C=C2C(=C1O)C3C(C(C(C(O3)CO)O)O)OC2=O)O.O Ambient -20°C Soluble in water. "Jain SK, Singh S, Khajuria A, et al. Pyrano-isochromanones as IL-6 Inhibitors: Synthesis, in Vitro and in Vivo Antiarthritic Activity. J Med Chem. 2014 Aug 28;57(16):7085-97. PMID: 25111439.

 

Liang J, Li Y, Liu X, et al. In vivo and in vitro antimalarial activity of bergenin. Biomed Rep. 2014 Mar;2(2):260-264. PMID: 24649107.

 

Zhang J, Nishimoto Y, Tokuda H, et al. Cancer chemopreventive effect of bergenin from Peltophorum pterocarpum wood. Chem Biodivers. 2013 Oct;10(10):1866-75. PMID: 24130029.

 

Kumar R, Patel DK, Prasad SK, et al. Type 2 antidiabetic activity of bergenin from the roots of Caesalpinia digyna Rottler. Fitoterapia. 2012 Mar;83(2):395-401. PMID: 22178680.

 

de Oliveira CM, Nonato FR, de Lima FO, et al. Antinociceptive properties of bergenin. J Nat Prod. 2011 Oct 28;74(10):2062-8. Erratum in: J Nat Prod. 2012 Feb 24;75(2):305.  PMID: 21939182.

 

Wang X, Tang S, Zhai H, et al. Studies on anti-tumor metastatic constituents from Ardisia Crenata. Zhongguo Zhong Yao Za Zhi. 2011 Apr;36(7):881-5. PMID: 21761727.

" Xi Not dangerous goods.

LKT B1853 1,4-Benzoquinone 100 g 44.9 Precursor in the synthesis of hydroquinone, antioxidant; 5-lipoxygenase inhibitor. 2,5-Cyclohexadiene-1,4-dione Quinone; p-quinone; 1,4-Cyclohexadienedione 106-51-4 ≥98% 108.09 C6H4O2 C1=CC(=O)C=CC1=O Ambient Ambient Slightly soluble in water. Soluble in alcohol, ether or alkalis. "Schaible AM, Filosa R, Temml V, et al. Elucidation of the molecular mechanism and the efficacy in vivo of a novel 1,4-benzoquinone that inhibits 5-lipoxygenase. Br J Pharmacol. 2014 May;171(9):2399-412. PMID: 24467325.

 

Kim MH, Jo SH, Ha KS, et al. Antimicrobial activities of 1,4-benzoquinones and wheat germ extract. J Microbiol Biotechnol. 2010 Aug;20(8):1204-9. PMID: 20798583.

" T, N "UN number: 2587     Class:  6.1     Packing group:  II

Proper shipping name:  Benzoquinone

Reportable quantity (RQ):  10 lbs.     Poison inhalation hazard:  No     Marine pollutant: Yes"

LKT B1853 1,4-Benzoquinone 500 g 162.2 Precursor in the synthesis of hydroquinone, antioxidant; 5-lipoxygenase inhibitor. 2,5-Cyclohexadiene-1,4-dione Quinone; p-quinone; 1,4-Cyclohexadienedione 106-51-4 ≥98% 108.09 C6H4O2 C1=CC(=O)C=CC1=O Ambient Ambient Slightly soluble in water. Soluble in alcohol, ether or alkalis. "Schaible AM, Filosa R, Temml V, et al. Elucidation of the molecular mechanism and the efficacy in vivo of a novel 1,4-benzoquinone that inhibits 5-lipoxygenase. Br J Pharmacol. 2014 May;171(9):2399-412. PMID: 24467325.

 

Kim MH, Jo SH, Ha KS, et al. Antimicrobial activities of 1,4-benzoquinones and wheat germ extract. J Microbiol Biotechnol. 2010 Aug;20(8):1204-9. PMID: 20798583.

" T, N "UN number: 2587     Class:  6.1     Packing group:  II

Proper shipping name:  Benzoquinone

Reportable quantity (RQ):  10 lbs.     Poison inhalation hazard:  No     Marine pollutant: Yes"

LKT B1855 O6-Benzylguanine 50 mg 56.3 MGMT inhibitor. 19916-73-5 ≥98% 241.25 C12H11N5O C1=CC=C(C=C1)COC2=NC(=NC3=C2NC=N3)N Ambient Ambient "Qian L, Zheng J, Wang K, et al. Cationic core-shell nanoparticles with carmustine contained within O6-benzylguanine shell for glioma therapy. Biomaterials. 2013 Nov;34(35):8968-78. PMID: 23953782.

 

Quinn JA, Jiang SX, Reardon DA, et al. Phase II trial of temozolomide plus O6-benzylguanine in adults with recurrent, temozolomide-resistant malignant glioma. J Clin Oncol. 2009 Mar 10;27(8):1262-7. PMID: 19204199.

 

Quinn JA, Jiang SX, Carter J, et al. Phase II trial of Gliadel plus O6-benzylguanine in adults with recurrent glioblastoma multiforme. Clin Cancer Res. 2009 Feb 1;15(3):1064-8. PMID: 19188181.

 

Friedman HS, Keir S, Pegg AE, et al. O6-benzylguanine-mediated enhancement of chemotherapy. Mol Cancer Ther. 2002 Sep;1(11):943-8. PMID: 12481416.

 

Friedman HS, Pluda J, Quinn JA, et al. Phase I trial of carmustine plus O6-benzylguanine for patients with recurrent or progressive malignant glioma. J Clin Oncol. 2000 Oct 15;18(20):3522-8. PMID: 11032594.

" Xi Not dangerous goods.

LKT B1855 O6-Benzylguanine 250 mg 234.5 MGMT inhibitor. 19916-73-5 ≥98% 241.25 C12H11N5O C1=CC=C(C=C1)COC2=NC(=NC3=C2NC=N3)N Ambient Ambient "Qian L, Zheng J, Wang K, et al. Cationic core-shell nanoparticles with carmustine contained within O6-benzylguanine shell for glioma therapy. Biomaterials. 2013 Nov;34(35):8968-78. PMID: 23953782.

 

Quinn JA, Jiang SX, Reardon DA, et al. Phase II trial of temozolomide plus O6-benzylguanine in adults with recurrent, temozolomide-resistant malignant glioma. J Clin Oncol. 2009 Mar 10;27(8):1262-7. PMID: 19204199.

 

Quinn JA, Jiang SX, Carter J, et al. Phase II trial of Gliadel plus O6-benzylguanine in adults with recurrent glioblastoma multiforme. Clin Cancer Res. 2009 Feb 1;15(3):1064-8. PMID: 19188181.

 

Friedman HS, Keir S, Pegg AE, et al. O6-benzylguanine-mediated enhancement of chemotherapy. Mol Cancer Ther. 2002 Sep;1(11):943-8. PMID: 12481416.

 

Friedman HS, Pluda J, Quinn JA, et al. Phase I trial of carmustine plus O6-benzylguanine for patients with recurrent or progressive malignant glioma. J Clin Oncol. 2000 Oct 15;18(20):3522-8. PMID: 11032594.

" Xi Not dangerous goods.

LKT B1855 O6-Benzylguanine 1 g 703.2 MGMT inhibitor. 19916-73-5 ≥98% 241.25 C12H11N5O C1=CC=C(C=C1)COC2=NC(=NC3=C2NC=N3)N Ambient Ambient "Qian L, Zheng J, Wang K, et al. Cationic core-shell nanoparticles with carmustine contained within O6-benzylguanine shell for glioma therapy. Biomaterials. 2013 Nov;34(35):8968-78. PMID: 23953782.

 

Quinn JA, Jiang SX, Reardon DA, et al. Phase II trial of temozolomide plus O6-benzylguanine in adults with recurrent, temozolomide-resistant malignant glioma. J Clin Oncol. 2009 Mar 10;27(8):1262-7. PMID: 19204199.

 

Quinn JA, Jiang SX, Carter J, et al. Phase II trial of Gliadel plus O6-benzylguanine in adults with recurrent glioblastoma multiforme. Clin Cancer Res. 2009 Feb 1;15(3):1064-8. PMID: 19188181.

 

Friedman HS, Keir S, Pegg AE, et al. O6-benzylguanine-mediated enhancement of chemotherapy. Mol Cancer Ther. 2002 Sep;1(11):943-8. PMID: 12481416.

 

Friedman HS, Pluda J, Quinn JA, et al. Phase I trial of carmustine plus O6-benzylguanine for patients with recurrent or progressive malignant glioma. J Clin Oncol. 2000 Oct 15;18(20):3522-8. PMID: 11032594.

" Xi Not dangerous goods.

LKT B1870 Berberine Chloride 5 g 39.5 Isoquinoline alkaloid found in various plant sources; prolyl oligopeptidase and AChE inhibitor, potential σ modulator. 633-65-8 ≥97% 371.82 C20H18NO4 Cl COC1=C(C2=C[N+]3=C(C=C2C=C1)C4=CC5=C(C=C4CC3)OCO5)OC.[Cl-] Protect from light. Ambient Ambient Soluble in boiling water. Slightly soluble in cold water. Soluble in methanol >20 mg/mL. Soluble in ethanol >2 mg/mL. Soluble in DMSO 74 mg/mL. Slightly soluble in chloroform. "Wang J, Peng Y, Liu Y, et al. Berberine, a natural compound, suppresses Hedgehog signaling pathway activity and cancer growth. BMC Cancer. 2015 Aug 22;15:595.

 

Huang L, Shi A, He F, et al. Synthesis, biological evaluation, and molecular modeling of berberine derivatives as potent acetylcholinesterase inhibitors. Bioorg Med Chem. 2010 Feb;18(3):1244-51. PMID: 20056426.

 

Tarrago T, Kichik N, Seguí J, et al. The natural product berberine is a human prolyl oligopeptidase inhibitor. ChemMedChem. 2007 Mar;2(3):354-9. PMID: 17295371.

 

Kulkarni SK, Dhir A. Berberine: a plant alkaloid with therapeutic potential for central nervous system disorders. Phytother Res. 2010 Mar;24(3):317-24. PMID: 19998323.

 

Kulkarni SK, Dhir A. On the mechanism of antidepressant-like action of berberine chloride. Eur J Pharmacol. 2008 Jul 28;589(1-3):163-72. PMID: 18585703.

 

" Xn, Xi Not dangerous goods.

LKT B1870 Berberine Chloride 10 g 54.4 Isoquinoline alkaloid found in various plant sources; prolyl oligopeptidase and AChE inhibitor, potential σ modulator. 633-65-8 ≥97% 371.82 C20H18NO4 Cl COC1=C(C2=C[N+]3=C(C=C2C=C1)C4=CC5=C(C=C4CC3)OCO5)OC.[Cl-] Protect from light. Ambient Ambient Soluble in boiling water. Slightly soluble in cold water. Soluble in methanol >20 mg/mL. Soluble in ethanol >2 mg/mL. Soluble in DMSO 74 mg/mL. Slightly soluble in chloroform. "Wang J, Peng Y, Liu Y, et al. Berberine, a natural compound, suppresses Hedgehog signaling pathway activity and cancer growth. BMC Cancer. 2015 Aug 22;15:595.

 

Huang L, Shi A, He F, et al. Synthesis, biological evaluation, and molecular modeling of berberine derivatives as potent acetylcholinesterase inhibitors. Bioorg Med Chem. 2010 Feb;18(3):1244-51. PMID: 20056426.

 

Tarrago T, Kichik N, Seguí J, et al. The natural product berberine is a human prolyl oligopeptidase inhibitor. ChemMedChem. 2007 Mar;2(3):354-9. PMID: 17295371.

 

Kulkarni SK, Dhir A. Berberine: a plant alkaloid with therapeutic potential for central nervous system disorders. Phytother Res. 2010 Mar;24(3):317-24. PMID: 19998323.

 

Kulkarni SK, Dhir A. On the mechanism of antidepressant-like action of berberine chloride. Eur J Pharmacol. 2008 Jul 28;589(1-3):163-72. PMID: 18585703.

 

" Xn, Xi Not dangerous goods.

LKT B1874 Bestatin Hydrochloride 1 mg 40.7 Dipeptide; aminopeptidase (N/CD13) inhibitor. N-[(2S,3R)-3-Amino-2-hydroxy-1-oxo-4-phenylbutyl]-L-leucine hydrochloride Ubenimex hydrochloride 65391-42-6 ≥98% 344.87 C16H24N2O4 HCl CC(C)CC(C(=O)O)NC(=O)C(C(CC1=CC=CC=C1)N)O.Cl Ambient -20°C Soluble in water (25mg.mL). "Hitzerd SM, Verbrugge SE, Ossenkoppele G, et al. Positioning of aminopeptidase inhibitors in next generation cancer therapy. Amino Acids. 2014 Apr;46(4):793-808. PMID: 24385243.

 

Qian X, He J, Zhao Y, et al. Inhibition of p38 MAPK Phosphorylation Is Critical for Bestatin to Enhance ATRA-Induced Cell Differentiation in Acute Promyelocytic Leukemia NB4 Cells. Am J Ther. 2013 Oct 17. [Epub ahead of print]. PMID: 24141198.

 

Jia MR, Wei T, Xu WF. The Analgesic Activity of Bestatin as a Potent APN Inhibitor. Front Neurosci. 2010 Jun 28;4:50. PMID: 20631848.

" Xn, Xi Not dangerous goods.

LKT "B1874

" Bestatin Hydrochloride 5 mg 66.7 Dipeptide; aminopeptidase (N/CD13) inhibitor. N-[(2S,3R)-3-Amino-2-hydroxy-1-oxo-4-phenylbutyl]-L-leucine hydrochloride Ubenimex hydrochloride 65391-42-6 ≥98% 344.87 C16H24N2O4 HCl CC(C)CC(C(=O)O)NC(=O)C(C(CC1=CC=CC=C1)N)O.Cl Ambient -20°C Soluble in water (25mg.mL). "Hitzerd SM, Verbrugge SE, Ossenkoppele G, et al. Positioning of aminopeptidase inhibitors in next generation cancer therapy. Amino Acids. 2014 Apr;46(4):793-808. PMID: 24385243.

 

Qian X, He J, Zhao Y, et al. Inhibition of p38 MAPK Phosphorylation Is Critical for Bestatin to Enhance ATRA-Induced Cell Differentiation in Acute Promyelocytic Leukemia NB4 Cells. Am J Ther. 2013 Oct 17. [Epub ahead of print]. PMID: 24141198.

 

Jia MR, Wei T, Xu WF. The Analgesic Activity of Bestatin as a Potent APN Inhibitor. Front Neurosci. 2010 Jun 28;4:50. PMID: 20631848.

" Xn, Xi Not dangerous goods.

LKT "B1874

" Bestatin Hydrochloride 10 mg 125 Dipeptide; aminopeptidase (N/CD13) inhibitor. N-[(2S,3R)-3-Amino-2-hydroxy-1-oxo-4-phenylbutyl]-L-leucine hydrochloride Ubenimex hydrochloride 65391-42-6 ≥98% 344.87 C16H24N2O4 HCl CC(C)CC(C(=O)O)NC(=O)C(C(CC1=CC=CC=C1)N)O.Cl Ambient -20°C Soluble in water (25mg.mL). "Hitzerd SM, Verbrugge SE, Ossenkoppele G, et al. Positioning of aminopeptidase inhibitors in next generation cancer therapy. Amino Acids. 2014 Apr;46(4):793-808. PMID: 24385243.

 

Qian X, He J, Zhao Y, et al. Inhibition of p38 MAPK Phosphorylation Is Critical for Bestatin to Enhance ATRA-Induced Cell Differentiation in Acute Promyelocytic Leukemia NB4 Cells. Am J Ther. 2013 Oct 17. [Epub ahead of print]. PMID: 24141198.

 

Jia MR, Wei T, Xu WF. The Analgesic Activity of Bestatin as a Potent APN Inhibitor. Front Neurosci. 2010 Jun 28;4:50. PMID: 20631848.

" Xn, Xi Not dangerous goods.

LKT B1876 Betamethasone 100 mg 187.3 Steroid; glucocorticoid agonist. (11β,16β)-9-Fluoro-11,17,21-trihydroxy-16-methylpregna-1,4-diene-3,20-dione Becort; Betnelan; Celestene; Dermabet; Diprolene; Visubeta 378-44-9 ≥98% 392.46 C22H29FO5 CC1CC2C3CCC4=CC(=O)C=CC4(C3(C(CC2(C1(C(=O)CO)O)C)O)F)C Ambient 4°C Insoluble in water, ethanol (15 mg/mL). "Shepherd J, Taheri A, Feldman SR. Once-daily topical treatment for psoriasis: calcipotriene + betamethasone two-compound topical formulation. Clin Cosmet Investig Dermatol. 2013 Dec 19;7:19-22. PMID: 24379688.

 

Waffarn F, Davis EP. Effects of antenatal corticosteroids on the hypothalamic-pituitary-adrenocortical axis of the fetus and newborn: experimental findings and clinical considerations. Am J Obstet Gynecol. 2012 Dec;207(6):446-54. PMID: 22840973.

" Not dangerous goods.

LKT B1876 Betamethasone 500 mg 612.5 Steroid; glucocorticoid agonist. (11β,16β)-9-Fluoro-11,17,21-trihydroxy-16-methylpregna-1,4-diene-3,20-dione Becort; Betnelan; Celestene; Dermabet; Diprolene; Visubeta 378-44-9 ≥98% 392.46 C22H29FO5 CC1CC2C3CCC4=CC(=O)C=CC4(C3(C(CC2(C1(C(=O)CO)O)C)O)F)C Ambient 4°C Insoluble in water, ethanol (15 mg/mL). "Shepherd J, Taheri A, Feldman SR. Once-daily topical treatment for psoriasis: calcipotriene + betamethasone two-compound topical formulation. Clin Cosmet Investig Dermatol. 2013 Dec 19;7:19-22. PMID: 24379688.

 

Waffarn F, Davis EP. Effects of antenatal corticosteroids on the hypothalamic-pituitary-adrenocortical axis of the fetus and newborn: experimental findings and clinical considerations. Am J Obstet Gynecol. 2012 Dec;207(6):446-54. PMID: 22840973.

" Not dangerous goods.

LKT B1878 Betamethasone 21-Phosphate Sodium 250 mg 122.9 Steroid; glucocorticoid agonist. (11β,16β)-9-Fluoro-11,17,21-trihydroxy-16-methylpregna-1,4-diene-3,20-dione 21-phosphate disodium salt Betamethasone 21-Phosphate disodium salt; Bentelan; Betnesol; Celestan; Vista-Methasone 151-73-5 ≥98% 516.4 C22H28FNa2O8P CC1CC2C3CCC4=CC(=O)C=CC4(C3(C(CC2(C1(C(=O)COP(=O)([O-])[O-])O)C)O)F)C.[Na+].[Na+] Ambient Ambient Soluble in water (500 mg/mL). Slightly soluble in alcohol (2 mg/mL). Insoluble in chloroform. "Shepherd J, Taheri A, Feldman SR. Once-daily topical treatment for psoriasis: calcipotriene + betamethasone two-compound topical formulation. Clin Cosmet Investig Dermatol. 2013 Dec 19;7:19-22. PMID: 24379688.

 

Waffarn F, Davis EP. Effects of antenatal corticosteroids on the hypothalamic-pituitary-adrenocortical axis of the fetus and newborn: experimental findings and clinical considerations. Am J Obstet Gynecol. 2012 Dec;207(6):446-54. PMID: 22840973.

" Not dangerous goods.

LKT B1878 Betamethasone 21-Phosphate Sodium 1 g 362.4 Steroid; glucocorticoid agonist. (11β,16β)-9-Fluoro-11,17,21-trihydroxy-16-methylpregna-1,4-diene-3,20-dione 21-phosphate disodium salt Betamethasone 21-Phosphate disodium salt; Bentelan; Betnesol; Celestan; Vista-Methasone 151-73-5 ≥98% 516.4 C22H28FNa2O8P CC1CC2C3CCC4=CC(=O)C=CC4(C3(C(CC2(C1(C(=O)COP(=O)([O-])[O-])O)C)O)F)C.[Na+].[Na+] Ambient Ambient Soluble in water (500 mg/mL). Slightly soluble in alcohol (2 mg/mL). Insoluble in chloroform. "Shepherd J, Taheri A, Feldman SR. Once-daily topical treatment for psoriasis: calcipotriene + betamethasone two-compound topical formulation. Clin Cosmet Investig Dermatol. 2013 Dec 19;7:19-22. PMID: 24379688.

 

Waffarn F, Davis EP. Effects of antenatal corticosteroids on the hypothalamic-pituitary-adrenocortical axis of the fetus and newborn: experimental findings and clinical considerations. Am J Obstet Gynecol. 2012 Dec;207(6):446-54. PMID: 22840973.

" Not dangerous goods.

LKT F4682 Fluconazole 500 mg 47.6 Triazole; 14-α demethylase inhibitor. α-(2,4-Difluorophenyl)-α-(1H-1,2,4-triazol-1- ylmethyl)-1H-1,2,4-triazole-1-ethanol Biozolene; Diflucan; Elazor; Triflucan 86386-73-4 ≥98% 306.27 C13H12F2N6O C1=CC(=C(C=C1F)F)C(CN2C=NC=N2)(CN3C=NC=N3)O Ambient Ambient Slightly soluble in water 1mg/mL.  Soluble in ethanol (61mg/mL), ethyl acetate and methanol.  DMSO to 100 mM. "Cuenca-Estrella M. Antifungal agents in the treatment of systemic infections: Relevance of mechanism of action, activity profile and resistances. Rev Esp Quimioter. 2010 Dec;23(4):169-76. PMID: 21191554.

 

Mansfield BE, Oltean HN, Oliver BG, et al. Azole drugs are imported by facilitated diffusion in Candida albicans and other pathogenic fungi. PLoS Pathog. 2010 Sep 30;6(9):e1001126. PMID: 20941354.

 

Matsumoto Y, Miyazaki S, Fukunaga DH, et al. Quantitative evaluation of cryptococcal pathogenesis and antifungal drugs using a silkworm infection model with Cryptococcus neoformans. J Appl Microbiol. 2012 Jan;112(1):138-146. PMID: 22040451.

" Xn Not dangerous goods.

LKT F4682 Fluconazole 1 g 81.6 Triazole; 14-α demethylase inhibitor. α-(2,4-Difluorophenyl)-α-(1H-1,2,4-triazol-1- ylmethyl)-1H-1,2,4-triazole-1-ethanol Biozolene; Diflucan; Elazor; Triflucan 86386-73-4 ≥98% 306.27 C13H12F2N6O C1=CC(=C(C=C1F)F)C(CN2C=NC=N2)(CN3C=NC=N3)O Ambient Ambient Slightly soluble in water 1mg/mL.  Soluble in ethanol (61mg/mL), ethyl acetate and methanol.  DMSO to 100 mM. "Cuenca-Estrella M. Antifungal agents in the treatment of systemic infections: Relevance of mechanism of action, activity profile and resistances. Rev Esp Quimioter. 2010 Dec;23(4):169-76. PMID: 21191554.

 

Mansfield BE, Oltean HN, Oliver BG, et al. Azole drugs are imported by facilitated diffusion in Candida albicans and other pathogenic fungi. PLoS Pathog. 2010 Sep 30;6(9):e1001126. PMID: 20941354.

 

Matsumoto Y, Miyazaki S, Fukunaga DH, et al. Quantitative evaluation of cryptococcal pathogenesis and antifungal drugs using a silkworm infection model with Cryptococcus neoformans. J Appl Microbiol. 2012 Jan;112(1):138-146. PMID: 22040451.

" Xn Not dangerous goods.

LKT F4682 Fluconazole 5 g 240.2 Triazole; 14-α demethylase inhibitor. α-(2,4-Difluorophenyl)-α-(1H-1,2,4-triazol-1- ylmethyl)-1H-1,2,4-triazole-1-ethanol Biozolene; Diflucan; Elazor; Triflucan 86386-73-4 ≥98% 306.27 C13H12F2N6O C1=CC(=C(C=C1F)F)C(CN2C=NC=N2)(CN3C=NC=N3)O Ambient Ambient Slightly soluble in water 1mg/mL.  Soluble in ethanol (61mg/mL), ethyl acetate and methanol.  DMSO to 100 mM. "Cuenca-Estrella M. Antifungal agents in the treatment of systemic infections: Relevance of mechanism of action, activity profile and resistances. Rev Esp Quimioter. 2010 Dec;23(4):169-76. PMID: 21191554.

 

Mansfield BE, Oltean HN, Oliver BG, et al. Azole drugs are imported by facilitated diffusion in Candida albicans and other pathogenic fungi. PLoS Pathog. 2010 Sep 30;6(9):e1001126. PMID: 20941354.

 

Matsumoto Y, Miyazaki S, Fukunaga DH, et al. Quantitative evaluation of cryptococcal pathogenesis and antifungal drugs using a silkworm infection model with Cryptococcus neoformans. J Appl Microbiol. 2012 Jan;112(1):138-146. PMID: 22040451.

" Xn Not dangerous goods.

LKT T0154 Tanshinone IIA 10 mg 95.1 Found in Salvia; MAG lipase inhibitor. Phenanthro(1,2-b)furan-10,11-dione, 6,7,8,9-tetrahydro- 1,6,6-trimethyl- Dan Shen Ketone; Tanshinone II; Tanshinone B 568-72-9 ≥93% 294.34 C19H18O3 CC1=COC2=C1C(=O)C(=O)C3=C2C=CC4=C3CCCC4(C)C Ambient 4°C Soluble in DMSO. "Maione F, De Feo V, Caiazzo E, et al. Tanshinone IIA, a major component of Salvia milthorriza Bunge, inhibits platelet activation via Erk-2 signaling pathway. J Ethnopharmacol. 2014 Sep 11;155(2):1236-42. PMID: 25038434.

 

Yang L, Guo H, Dong L, et al. Tanshinone IIA inhibits the growth, attenuates the stemness and induces the apoptosis of human glioma stem cells. Oncol Rep. 2014 Sep;32(3):1303-11. PMID: 24970314.

 

Jiang P, Li C, Xiang Z, et al. Tanshinone IIA reduces the risk of Alzheimer's disease by inhibiting iNOS, MMP 2 and NF κBp65 transcription and translation in the temporal lobes of rat models of Alzheimer's disease. Mol Med Rep. 2014 Aug;10(2):689-94. PMID: 24859152.

 

Chang CC, Chu CF, Wang CN, et al. The anti-atherosclerotic effect of tanshinone IIA is associated with the inhibition of TNF-α-induced VCAM-1, ICAM-1 and CX3CL1 expression. Phytomedicine. 2014 Feb 15;21(3):207-16. PMID: 24157079.

 

Lin C, Wang L, Wang H, et al. Tanshinone IIA inhibits breast cancer stem cells growth in vitro and in vivo through attenuation of IL-6/STAT3/NF-kB signaling pathways. J Cell Biochem. 2013 Sep;114(9):2061-70. PMID: 23553622.

 

Li W, Li J, Ashok M, et al. A cardiovascular drug rescues mice from lethal sepsis by selectively attentuating a late-acting proinflammatory mediator, high mobility group box 1. J Immunol. 2007 Mar 15;178(6):3856-3864. PMID: 17339485.

 

Zhang Y, Won SH, Jiang C, et al. Tanshinones fmor Chinese medicinal herb Danshen (Salvia miltiorrhiza Bunge) suppress prostate cancer growth and androgen receptor signaling. Pharm Res. 2012 Jun;29(6):1595-1608. PMID: 22281759.

" None Not dangerous goods.

LKT T0154 Tanshinone IIA 25 mg 197.1 Found in Salvia; MAG lipase inhibitor. Phenanthro(1,2-b)furan-10,11-dione, 6,7,8,9-tetrahydro- 1,6,6-trimethyl- Dan Shen Ketone; Tanshinone II; Tanshinone B 568-72-9 ≥93% 294.34 C19H18O3 CC1=COC2=C1C(=O)C(=O)C3=C2C=CC4=C3CCCC4(C)C Ambient 4°C Soluble in DMSO. "Maione F, De Feo V, Caiazzo E, et al. Tanshinone IIA, a major component of Salvia milthorriza Bunge, inhibits platelet activation via Erk-2 signaling pathway. J Ethnopharmacol. 2014 Sep 11;155(2):1236-42. PMID: 25038434.

 

Yang L, Guo H, Dong L, et al. Tanshinone IIA inhibits the growth, attenuates the stemness and induces the apoptosis of human glioma stem cells. Oncol Rep. 2014 Sep;32(3):1303-11. PMID: 24970314.

 

Jiang P, Li C, Xiang Z, et al. Tanshinone IIA reduces the risk of Alzheimer's disease by inhibiting iNOS, MMP 2 and NF κBp65 transcription and translation in the temporal lobes of rat models of Alzheimer's disease. Mol Med Rep. 2014 Aug;10(2):689-94. PMID: 24859152.

 

Chang CC, Chu CF, Wang CN, et al. The anti-atherosclerotic effect of tanshinone IIA is associated with the inhibition of TNF-α-induced VCAM-1, ICAM-1 and CX3CL1 expression. Phytomedicine. 2014 Feb 15;21(3):207-16. PMID: 24157079.

 

Lin C, Wang L, Wang H, et al. Tanshinone IIA inhibits breast cancer stem cells growth in vitro and in vivo through attenuation of IL-6/STAT3/NF-kB signaling pathways. J Cell Biochem. 2013 Sep;114(9):2061-70. PMID: 23553622.

 

Li W, Li J, Ashok M, et al. A cardiovascular drug rescues mice from lethal sepsis by selectively attentuating a late-acting proinflammatory mediator, high mobility group box 1. J Immunol. 2007 Mar 15;178(6):3856-3864. PMID: 17339485.

 

Zhang Y, Won SH, Jiang C, et al. Tanshinones fmor Chinese medicinal herb Danshen (Salvia miltiorrhiza Bunge) suppress prostate cancer growth and androgen receptor signaling. Pharm Res. 2012 Jun;29(6):1595-1608. PMID: 22281759.

" None Not dangerous goods.

LKT T0154 Tanshinone IIA 100 mg 611.5 Found in Salvia; MAG lipase inhibitor. Phenanthro(1,2-b)furan-10,11-dione, 6,7,8,9-tetrahydro- 1,6,6-trimethyl- Dan Shen Ketone; Tanshinone II; Tanshinone B 568-72-9 ≥93% 294.34 C19H18O3 CC1=COC2=C1C(=O)C(=O)C3=C2C=CC4=C3CCCC4(C)C Ambient 4°C Soluble in DMSO. "Maione F, De Feo V, Caiazzo E, et al. Tanshinone IIA, a major component of Salvia milthorriza Bunge, inhibits platelet activation via Erk-2 signaling pathway. J Ethnopharmacol. 2014 Sep 11;155(2):1236-42. PMID: 25038434.

 

Yang L, Guo H, Dong L, et al. Tanshinone IIA inhibits the growth, attenuates the stemness and induces the apoptosis of human glioma stem cells. Oncol Rep. 2014 Sep;32(3):1303-11. PMID: 24970314.

 

Jiang P, Li C, Xiang Z, et al. Tanshinone IIA reduces the risk of Alzheimer's disease by inhibiting iNOS, MMP 2 and NF κBp65 transcription and translation in the temporal lobes of rat models of Alzheimer's disease. Mol Med Rep. 2014 Aug;10(2):689-94. PMID: 24859152.

 

Chang CC, Chu CF, Wang CN, et al. The anti-atherosclerotic effect of tanshinone IIA is associated with the inhibition of TNF-α-induced VCAM-1, ICAM-1 and CX3CL1 expression. Phytomedicine. 2014 Feb 15;21(3):207-16. PMID: 24157079.

 

Lin C, Wang L, Wang H, et al. Tanshinone IIA inhibits breast cancer stem cells growth in vitro and in vivo through attenuation of IL-6/STAT3/NF-kB signaling pathways. J Cell Biochem. 2013 Sep;114(9):2061-70. PMID: 23553622.

 

Li W, Li J, Ashok M, et al. A cardiovascular drug rescues mice from lethal sepsis by selectively attentuating a late-acting proinflammatory mediator, high mobility group box 1. J Immunol. 2007 Mar 15;178(6):3856-3864. PMID: 17339485.

 

Zhang Y, Won SH, Jiang C, et al. Tanshinones fmor Chinese medicinal herb Danshen (Salvia miltiorrhiza Bunge) suppress prostate cancer growth and androgen receptor signaling. Pharm Res. 2012 Jun;29(6):1595-1608. PMID: 22281759.

" None Not dangerous goods.

LKT C0365 Carvedilol 1 g 111 FIASMA; α1- and β1/2-adrenergic antagonist. 1-(99H-Carbazol-4-yloxy)-3-[[2-(2-methoxyphenoxy)ethyl]amino]-2-propanol Coreg; Dimitone; Eucardic; Kredex; Querto 72956-09-3 ≥98% 406.47 C24H26N2O4 COC1=CC=CC=C1OCCNCC(COC2=CC=CC3=C2C4=CC=CC=C4N3)O Ambient 4°C Soluble in DMSO (>20 mg/mL), and methylene chloride. Sparingly soluble in ethanol(4 mg/mL), isopropanol and ethyl ether. Insoluble in water (0.02 mg/mL). "Arab HH, El-Sawalhi MM. Carvedilol alleviates adjuvant-induced arthritis and subcutaneous air pouch edema: modulation of oxidative stress and inflammatory mediators. Toxicol Appl Pharmacol. 2013 Apr 15;268(2):241-8. PMID: 23360886.

 

Kornhuber J, Muehlbacher M, Trapp S, et al. Identification of novel functional inhibitors of acid sphingomyelinase. PLoS One. 2011;6(8):e23852. PMID: 21909365.

 

Stafylas PC, Sarafidis PA. Carvedilol in hypertension treatment. Vasc Health Risk Manag. 2008;4(1):23-30. PMID: 18629377.

" Xn, Xi, N "UN number: 3077     Class: 9     Packing Group: III

Proper shipping name: Environmentally hazardous substance, solid, n.o.s. (Carvedilol)"

LKT C0365 Carvedilol 5 g 415.8 FIASMA; α1- and β1/2-adrenergic antagonist. 1-(99H-Carbazol-4-yloxy)-3-[[2-(2-methoxyphenoxy)ethyl]amino]-2-propanol Coreg; Dimitone; Eucardic; Kredex; Querto 72956-09-3 ≥98% 406.47 C24H26N2O4 COC1=CC=CC=C1OCCNCC(COC2=CC=CC3=C2C4=CC=CC=C4N3)O Ambient 4°C Soluble in DMSO (>20 mg/mL), and methylene chloride. Sparingly soluble in ethanol(4 mg/mL), isopropanol and ethyl ether. Insoluble in water (0.02 mg/mL). "Arab HH, El-Sawalhi MM. Carvedilol alleviates adjuvant-induced arthritis and subcutaneous air pouch edema: modulation of oxidative stress and inflammatory mediators. Toxicol Appl Pharmacol. 2013 Apr 15;268(2):241-8. PMID: 23360886.

 

Kornhuber J, Muehlbacher M, Trapp S, et al. Identification of novel functional inhibitors of acid sphingomyelinase. PLoS One. 2011;6(8):e23852. PMID: 21909365.

 

Stafylas PC, Sarafidis PA. Carvedilol in hypertension treatment. Vasc Health Risk Manag. 2008;4(1):23-30. PMID: 18629377.

" Xn, Xi, N "UN number: 3077     Class: 9     Packing Group: III

Proper shipping name: Environmentally hazardous substance, solid, n.o.s. (Carvedilol)"

LKT C0365 Carvedilol 10 g 739.5 FIASMA; α1- and β1/2-adrenergic antagonist. 1-(99H-Carbazol-4-yloxy)-3-[[2-(2-methoxyphenoxy)ethyl]amino]-2-propanol Coreg; Dimitone; Eucardic; Kredex; Querto 72956-09-3 ≥98% 406.47 C24H26N2O4 COC1=CC=CC=C1OCCNCC(COC2=CC=CC3=C2C4=CC=CC=C4N3)O Ambient 4°C Soluble in DMSO (>20 mg/mL), and methylene chloride. Sparingly soluble in ethanol(4 mg/mL), isopropanol and ethyl ether. Insoluble in water (0.02 mg/mL). "Arab HH, El-Sawalhi MM. Carvedilol alleviates adjuvant-induced arthritis and subcutaneous air pouch edema: modulation of oxidative stress and inflammatory mediators. Toxicol Appl Pharmacol. 2013 Apr 15;268(2):241-8. PMID: 23360886.

 

Kornhuber J, Muehlbacher M, Trapp S, et al. Identification of novel functional inhibitors of acid sphingomyelinase. PLoS One. 2011;6(8):e23852. PMID: 21909365.

 

Stafylas PC, Sarafidis PA. Carvedilol in hypertension treatment. Vasc Health Risk Manag. 2008;4(1):23-30. PMID: 18629377.

" Xn, Xi, N "UN number: 3077     Class: 9     Packing Group: III

Proper shipping name: Environmentally hazardous substance, solid, n.o.s. (Carvedilol)"

LKT B1879 Betamethasone Valerate 100 mg 163.2 Synthetic steroid hormone; glucocorticoid agonist. 2152-44-5 ≥98% 476.58 C27H37FO6 CCCCC(=O)OC1(C(CC2C1(CC(C3(C2CCC4=CC(=O)C=CC43C)F)O)C)C)C(=O)CO Ambient Ambient Insoluble in water.  Ethanol (62 mg/mL). Soluble in acetone, DMSO. "Naldi L, Yawalkar N, Kaszuba A, et al. Efficacy and safety of the Betamethasone valerate 0.1% plaster in mild-to-moderate chronic plaque psoriasis: a randomized, parallel-group, active-controlled, phase III study. Am J Clin Dermatol. 2011 Jun 1;12(3):191-201. PMID: 21284407.

 

Meindl S, Vaculik C, Meingassner JG, et al. Differential effects of corticosteroids and pimecrolimus on the developing skin immune system in humans and mice. J Invest Dermatol. 2009 Sep;129(9):2184-92. PMID: 19295616.

 

Leivo T, Arjomaa P, Oivula J, et al. Differential modulation of transforming growth factor-beta by betamethasone-17- valerate and isotretinoin: corticosteroid decreases and isotretinoin increases the level of transforming growth factor-beta in suction blister fluid. Skin Pharmacol Appl Skin Physiol. 2000 May-Aug;13(3-4):150-6. PMID: 10859533.

 

Marks R, Sawyer M. Glucocorticoid-induced vasoconstriction in human skin. An inhibitory role on phospholipase A2 activity. Arch Dermatol. 1986 Aug;122(8):881-3. PMID: 2874773.

" None Not dangerous goods.

LKT B1879 Betamethasone Valerate 500 mg 543.6 Synthetic steroid hormone; glucocorticoid agonist. 2152-44-5 ≥98% 476.58 C27H37FO6 CCCCC(=O)OC1(C(CC2C1(CC(C3(C2CCC4=CC(=O)C=CC43C)F)O)C)C)C(=O)CO Ambient Ambient Insoluble in water.  Ethanol (62 mg/mL). Soluble in acetone, DMSO. "Naldi L, Yawalkar N, Kaszuba A, et al. Efficacy and safety of the Betamethasone valerate 0.1% plaster in mild-to-moderate chronic plaque psoriasis: a randomized, parallel-group, active-controlled, phase III study. Am J Clin Dermatol. 2011 Jun 1;12(3):191-201. PMID: 21284407.

 

Meindl S, Vaculik C, Meingassner JG, et al. Differential effects of corticosteroids and pimecrolimus on the developing skin immune system in humans and mice. J Invest Dermatol. 2009 Sep;129(9):2184-92. PMID: 19295616.

 

Leivo T, Arjomaa P, Oivula J, et al. Differential modulation of transforming growth factor-beta by betamethasone-17- valerate and isotretinoin: corticosteroid decreases and isotretinoin increases the level of transforming growth factor-beta in suction blister fluid. Skin Pharmacol Appl Skin Physiol. 2000 May-Aug;13(3-4):150-6. PMID: 10859533.

 

Marks R, Sawyer M. Glucocorticoid-induced vasoconstriction in human skin. An inhibitory role on phospholipase A2 activity. Arch Dermatol. 1986 Aug;122(8):881-3. PMID: 2874773.

" None Not dangerous goods.

LKT B1898 Bezafibrate 1 g 33.9 Fibrate; PPARα agonist. 2-[4-[2-[(4-Chlorobenzoyl)amino]ethyl]phenoxy]-2- methylpropanoic acid Befizal; Bezatol; Cedur; Difaterol 41859-67-0 ≥98% 361.82 C19H20ClNO4 CC(C)(C(=O)O)OC1=CC=C(C=C1)CCNC(=O)C2=CC=C(C=C2)Cl Ambient Ambient Soluble in DMSO (50mg/mL). "Skrypnyk N, Chen X, Hu W, et al. PPARα activation can help prevent and treat non-small cell lung cancer. Cancer Res. 2014 Jan 15;74(2):621-31. PMID: 24302581.

 

Zhong X, Xiu LL, Wei GH, et al. Bezafibrate enhances proliferation and differentiation of osteoblastic MC3T3-E1 cells via AMPK and eNOS activation. Acta Pharmacol Sin. 2011 May;32(5):591-600. PMID: 21499286.

 

Tenenbaum A, Motro M, Fisman EZ, et al. Bezafibrate for the secondary prevention of myocardial infarction in patients with metabolic syndrome. Arch Intern Med. 2005 May 23;165(10):1154-60. PMID: 15911729.

 

Tenenbaum A, Motro M, Fisman EZ, et al. Peroxisome proliferator-activated receptor ligand bezafibrate for prevention of type 2 diabetes mellitus in patients with coronary artery disease. Circulation. 2004 May 11;109(18):2197-202. PMID: 15123532.

 

Bezafibrate Infarction Prevention (BIP) study. Secondary prevention by raising HDL cholesterol and reducing triglycerides in patients with coronary artery disease. Circulation. 2000 Jul 4;102(1):21-7. PMID: 10880410.

" Xn Not dangerous goods.

LKT B1898 Bezafibrate 5 g 108.8 Fibrate; PPARα agonist. 2-[4-[2-[(4-Chlorobenzoyl)amino]ethyl]phenoxy]-2- methylpropanoic acid Befizal; Bezatol; Cedur; Difaterol 41859-67-0 ≥98% 361.82 C19H20ClNO4 CC(C)(C(=O)O)OC1=CC=C(C=C1)CCNC(=O)C2=CC=C(C=C2)Cl Ambient Ambient Soluble in DMSO (50mg/mL). "Skrypnyk N, Chen X, Hu W, et al. PPARα activation can help prevent and treat non-small cell lung cancer. Cancer Res. 2014 Jan 15;74(2):621-31. PMID: 24302581.

 

Zhong X, Xiu LL, Wei GH, et al. Bezafibrate enhances proliferation and differentiation of osteoblastic MC3T3-E1 cells via AMPK and eNOS activation. Acta Pharmacol Sin. 2011 May;32(5):591-600. PMID: 21499286.

 

Tenenbaum A, Motro M, Fisman EZ, et al. Bezafibrate for the secondary prevention of myocardial infarction in patients with metabolic syndrome. Arch Intern Med. 2005 May 23;165(10):1154-60. PMID: 15911729.

 

Tenenbaum A, Motro M, Fisman EZ, et al. Peroxisome proliferator-activated receptor ligand bezafibrate for prevention of type 2 diabetes mellitus in patients with coronary artery disease. Circulation. 2004 May 11;109(18):2197-202. PMID: 15123532.

 

Bezafibrate Infarction Prevention (BIP) study. Secondary prevention by raising HDL cholesterol and reducing triglycerides in patients with coronary artery disease. Circulation. 2000 Jul 4;102(1):21-7. PMID: 10880410.

" Xn Not dangerous goods.

LKT B1898 Bezafibrate 25 g 380.5 Fibrate; PPARα agonist. 2-[4-[2-[(4-Chlorobenzoyl)amino]ethyl]phenoxy]-2- methylpropanoic acid Befizal; Bezatol; Cedur; Difaterol 41859-67-0 ≥98% 361.82 C19H20ClNO4 CC(C)(C(=O)O)OC1=CC=C(C=C1)CCNC(=O)C2=CC=C(C=C2)Cl Ambient Ambient Soluble in DMSO (50mg/mL). "Skrypnyk N, Chen X, Hu W, et al. PPARα activation can help prevent and treat non-small cell lung cancer. Cancer Res. 2014 Jan 15;74(2):621-31. PMID: 24302581.

 

Zhong X, Xiu LL, Wei GH, et al. Bezafibrate enhances proliferation and differentiation of osteoblastic MC3T3-E1 cells via AMPK and eNOS activation. Acta Pharmacol Sin. 2011 May;32(5):591-600. PMID: 21499286.

 

Tenenbaum A, Motro M, Fisman EZ, et al. Bezafibrate for the secondary prevention of myocardial infarction in patients with metabolic syndrome. Arch Intern Med. 2005 May 23;165(10):1154-60. PMID: 15911729.

 

Tenenbaum A, Motro M, Fisman EZ, et al. Peroxisome proliferator-activated receptor ligand bezafibrate for prevention of type 2 diabetes mellitus in patients with coronary artery disease. Circulation. 2004 May 11;109(18):2197-202. PMID: 15123532.

 

Bezafibrate Infarction Prevention (BIP) study. Secondary prevention by raising HDL cholesterol and reducing triglycerides in patients with coronary artery disease. Circulation. 2000 Jul 4;102(1):21-7. PMID: 10880410.

" Xn Not dangerous goods.

LKT B3203 Biapenem 10 mg 65.6 β-lactam; penicillin binding protein inhibitor. "(4R,5R,6S)-3-(3,5-diaza-1-azoniabicyclo[3.3.0]octa-1,3-dien-7-ylsulfanyl)-6

-(1-hydroxyethyl)-4-methyl-7-oxo-1-azabicyclo[3.2.0]hept-2-ene-2-carboxylate" "6-(((4R,5S,6S)-2-Carboxy-6-((1R)-1-hydroxyethyl)-4-methyl-7-

oxo-1-azabicyclo(3.2.0)hept-2-en-3-yl)thio)-6,7-dihydro-5H-

pyrazolo(1,2-a)-s-triazol-4-ium hydroxide, inner salt;

L-627; CL-186,815;  LJ-C10,627" 120410-24-4 ≥98% 350.39 C15H18N4O4S CC1C2C(C(=O)N2C(=C1SC3CN4C=NC=[N+]4C3)C(=O)O)C(C)O Ambient Ambient "Wang X, Zhang X, Zong Z, et al. Biapenem versus meropenem in the treatment of bacterial infections: a multicenter, randomized, controlled clinical trial. Indian J Med Res. 2013 Dec;138(6):995-1002. PMID: 24521647.

 

Yamachika S, Sugihara C, Kamai Y, et al. Correlation between penicillin-binding protein 2 mutations and carbapenem resistance in Escherichia coli. J Med Microbiol. 2013 Mar;62(Pt 3):429-36. PMID: 23222859.

 

Yamada K, Yamamoto Y, Yanagihara K, et al. In vivo efficacy and pharmacokinetics of biapenem in a murine model of ventilator-associated pneumonia with Pseudomonas aeruginosa. J Infect Chemother. 2012 Aug;18(4):472-8. PMID: 22215228.

 

Aldridge KE, Morice N, Schiro DD. In vitro activity of biapenem (L-627), a new carbapenem, against anaerobes. Antimicrob Agents Chemother. 1994 Apr;38(4):889-93. PMID: 8031067.

" None Not dangerous goods.

LKT B3203 Biapenem 25 mg 112.5 β-lactam; penicillin binding protein inhibitor. "(4R,5R,6S)-3-(3,5-diaza-1-azoniabicyclo[3.3.0]octa-1,3-dien-7-ylsulfanyl)-6

-(1-hydroxyethyl)-4-methyl-7-oxo-1-azabicyclo[3.2.0]hept-2-ene-2-carboxylate" "6-(((4R,5S,6S)-2-Carboxy-6-((1R)-1-hydroxyethyl)-4-methyl-7-

oxo-1-azabicyclo(3.2.0)hept-2-en-3-yl)thio)-6,7-dihydro-5H-

pyrazolo(1,2-a)-s-triazol-4-ium hydroxide, inner salt;

L-627; CL-186,815;  LJ-C10,627" 120410-24-4 ≥98% 350.39 C15H18N4O4S CC1C2C(C(=O)N2C(=C1SC3CN4C=NC=[N+]4C3)C(=O)O)C(C)O Ambient Ambient "Wang X, Zhang X, Zong Z, et al. Biapenem versus meropenem in the treatment of bacterial infections: a multicenter, randomized, controlled clinical trial. Indian J Med Res. 2013 Dec;138(6):995-1002. PMID: 24521647.

 

Yamachika S, Sugihara C, Kamai Y, et al. Correlation between penicillin-binding protein 2 mutations and carbapenem resistance in Escherichia coli. J Med Microbiol. 2013 Mar;62(Pt 3):429-36. PMID: 23222859.

 

Yamada K, Yamamoto Y, Yanagihara K, et al. In vivo efficacy and pharmacokinetics of biapenem in a murine model of ventilator-associated pneumonia with Pseudomonas aeruginosa. J Infect Chemother. 2012 Aug;18(4):472-8. PMID: 22215228.

 

Aldridge KE, Morice N, Schiro DD. In vitro activity of biapenem (L-627), a new carbapenem, against anaerobes. Antimicrob Agents Chemother. 1994 Apr;38(4):889-93. PMID: 8031067.

" None Not dangerous goods.

LKT B3203 Biapenem 100 mg 255 β-lactam; penicillin binding protein inhibitor. "(4R,5R,6S)-3-(3,5-diaza-1-azoniabicyclo[3.3.0]octa-1,3-dien-7-ylsulfanyl)-6

-(1-hydroxyethyl)-4-methyl-7-oxo-1-azabicyclo[3.2.0]hept-2-ene-2-carboxylate" "6-(((4R,5S,6S)-2-Carboxy-6-((1R)-1-hydroxyethyl)-4-methyl-7-

oxo-1-azabicyclo(3.2.0)hept-2-en-3-yl)thio)-6,7-dihydro-5H-

pyrazolo(1,2-a)-s-triazol-4-ium hydroxide, inner salt;

L-627; CL-186,815;  LJ-C10,627" 120410-24-4 ≥98% 350.39 C15H18N4O4S CC1C2C(C(=O)N2C(=C1SC3CN4C=NC=[N+]4C3)C(=O)O)C(C)O Ambient Ambient "Wang X, Zhang X, Zong Z, et al. Biapenem versus meropenem in the treatment of bacterial infections: a multicenter, randomized, controlled clinical trial. Indian J Med Res. 2013 Dec;138(6):995-1002. PMID: 24521647.

 

Yamachika S, Sugihara C, Kamai Y, et al. Correlation between penicillin-binding protein 2 mutations and carbapenem resistance in Escherichia coli. J Med Microbiol. 2013 Mar;62(Pt 3):429-36. PMID: 23222859.

 

Yamada K, Yamamoto Y, Yanagihara K, et al. In vivo efficacy and pharmacokinetics of biapenem in a murine model of ventilator-associated pneumonia with Pseudomonas aeruginosa. J Infect Chemother. 2012 Aug;18(4):472-8. PMID: 22215228.

 

Aldridge KE, Morice N, Schiro DD. In vitro activity of biapenem (L-627), a new carbapenem, against anaerobes. Antimicrob Agents Chemother. 1994 Apr;38(4):889-93. PMID: 8031067.

" None Not dangerous goods.

LKT B3209 Bicalutamide 100 mg 54.4 AR antagonist. "N-(4-cyano-3-(trifluoromethyl)phenyl)-3-((4-

fluorophenyl)sulfonyl)-2-hydroxy-2-methyl-, (+-)- Propanamide

" Casodex 90357-06-5 ≥98% 430.37 C18H14F4N2O4S CC(CS(=O)(=O)C1=CC=C(C=C1)F)(C(=O)NC2=CC(=C(C=C2)C#N)C(F)(F)F)O Ambient Ambient Soluble in acetone, DMSO (86mg/m), ethanol (7 mg/mL) or THF. Slightly soluble in chloroform or ether. Practically insoluble in water. "Squillace RM, Miller D, Wardwell D, et al. Synergistic activity of the mTOR inhibitor ridaforolimus and the antiandrogen bicalutamide in prostate cancer models. Int J Oncol. 2012 Aug;41(2):425-32. PMID: 22614157.

 

Yan J, Xie B, Capodice JL, et al. Zyflamend inhibits the expression and function of androgen receptor and acts synergistically with bicalutimide to inhibit prostate cancer cell growth. Prostate. 2012 Feb;72(3):244-52. PMID: 21656835.

 

De Amicis F, Thirugnansampanthan J, Cui Y, et al. Androgen receptor overexpression induces tamoxifen resistance in human breast cancer cells. Breast Cancer Res Treat. 2010 May;121(1):1-11. PMID: 19533338.

" Xi Not dangerous goods.

LKT B3209 Bicalutamide 250 mg 88.3 AR antagonist. "N-(4-cyano-3-(trifluoromethyl)phenyl)-3-((4-

fluorophenyl)sulfonyl)-2-hydroxy-2-methyl-, (+-)- Propanamide

" Casodex 90357-06-5 ≥98% 430.37 C18H14F4N2O4S CC(CS(=O)(=O)C1=CC=C(C=C1)F)(C(=O)NC2=CC(=C(C=C2)C#N)C(F)(F)F)O Ambient Ambient Soluble in acetone, DMSO (86mg/m), ethanol (7 mg/mL) or THF. Slightly soluble in chloroform or ether. Practically insoluble in water. "Squillace RM, Miller D, Wardwell D, et al. Synergistic activity of the mTOR inhibitor ridaforolimus and the antiandrogen bicalutamide in prostate cancer models. Int J Oncol. 2012 Aug;41(2):425-32. PMID: 22614157.

 

Yan J, Xie B, Capodice JL, et al. Zyflamend inhibits the expression and function of androgen receptor and acts synergistically with bicalutimide to inhibit prostate cancer cell growth. Prostate. 2012 Feb;72(3):244-52. PMID: 21656835.

 

De Amicis F, Thirugnansampanthan J, Cui Y, et al. Androgen receptor overexpression induces tamoxifen resistance in human breast cancer cells. Breast Cancer Res Treat. 2010 May;121(1):1-11. PMID: 19533338.

" Xi Not dangerous goods.

LKT B3209 Bicalutamide 1 g 271.7 AR antagonist. "N-(4-cyano-3-(trifluoromethyl)phenyl)-3-((4-

fluorophenyl)sulfonyl)-2-hydroxy-2-methyl-, (+-)- Propanamide

" Casodex 90357-06-5 ≥98% 430.37 C18H14F4N2O4S CC(CS(=O)(=O)C1=CC=C(C=C1)F)(C(=O)NC2=CC(=C(C=C2)C#N)C(F)(F)F)O Ambient Ambient Soluble in acetone, DMSO (86mg/m), ethanol (7 mg/mL) or THF. Slightly soluble in chloroform or ether. Practically insoluble in water. "Squillace RM, Miller D, Wardwell S, et al. Synergistic activity of the mTOR inhibitor ridaforolimus and the antiandrogen bicalutamide in prostate cancer models. Int J Oncol. 2012 Aug;41(2):425-32. PMID: 22614157.

 

Yan J, Xie B, Capodice JL, et al. Zyflamend inhibits the expression and function of androgen receptor and acts synergistically with bicalutimide to inhibit prostate cancer cell growth. Prostate. 2012 Feb;72(3):244-52. PMID: 21656835.

 

De Amicis F, Thirugnansampanthan J, Cui Y, et al. Androgen receptor overexpression induces tamoxifen resistance in human breast cancer cells. Breast Cancer Res Treat. 2010 May;121(1):1-11. PMID: 19533338.

" Xi Not dangerous goods.

LKT B3210 R-Bicalutamide 100 mg 168 AR antagonist. "R-N-(4-cyano-3-(trifluoromethyl)phenyl)-3-((4-

fluorophenyl)sulfonyl)-2-hydroxy-2-methyl-, (+-)- Propanamide" 113299-40-4 ≥98% 430.37 C18H14F4N2O4S CC(CS(=O)(=O)C1=CC=C(C=C1)F)(C(=O)NC2=CC(=C(C=C2)C#N)C(F)(F)F)O Ambient Ambient water: 5mg/L "Squillace RM, Miller D, Wardwell S, et al. Synergistic activity of the mTOR inhibitor ridaforolimus and the antiandrogen bicalutamide in prostate cancer models. Int J Oncol. 2012 Aug;41(2):425-32. PMID: 22614157.

 

Yan J, Xie B, Capodice JL, et al. Zyflamend inhibits the expression and function of androgen receptor and acts synergistically with bicalutimide to inhibit prostate cancer cell growth. Prostate. 2012 Feb;72(3):244-52. PMID: 21656835.

" Not dangerous goods.

LKT B3210 R-Bicalutamide 250 mg 304.6 AR antagonist. "R-N-(4-cyano-3-(trifluoromethyl)phenyl)-3-((4-

fluorophenyl)sulfonyl)-2-hydroxy-2-methyl-, (+-)- Propanamide" 113299-40-4 ≥98% 430.37 C18H14F4N2O4S CC(CS(=O)(=O)C1=CC=C(C=C1)F)(C(=O)NC2=CC(=C(C=C2)C#N)C(F)(F)F)O Ambient Ambient water: 5mg/L "Squillace RM, Miller D, Wardwell S, et al. Synergistic activity of the mTOR inhibitor ridaforolimus and the antiandrogen bicalutamide in prostate cancer models. Int J Oncol. 2012 Aug;41(2):425-32. PMID: 22614157.

 

Yan J, Xie B, Capodice JL, et al. Zyflamend inhibits the expression and function of androgen receptor and acts synergistically with bicalutimide to inhibit prostate cancer cell growth. Prostate. 2012 Feb;72(3):244-52. PMID: 21656835.

" Not dangerous goods.

LKT B3210 R-Bicalutamide 1 g 915.9 AR antagonist. "R-N-(4-cyano-3-(trifluoromethyl)phenyl)-3-((4-

fluorophenyl)sulfonyl)-2-hydroxy-2-methyl-, (+-)- Propanamide" 113299-40-4 ≥98% 430.37 C18H14F4N2O4S CC(CS(=O)(=O)C1=CC=C(C=C1)F)(C(=O)NC2=CC(=C(C=C2)C#N)C(F)(F)F)O Ambient Ambient water: 5mg/L "Squillace RM, Miller D, Wardwell S, et al. Synergistic activity of the mTOR inhibitor ridaforolimus and the antiandrogen bicalutamide in prostate cancer models. Int J Oncol. 2012 Aug;41(2):425-32. PMID: 22614157.

 

Yan J, Xie B, Capodice JL, et al. Zyflamend inhibits the expression and function of androgen receptor and acts synergistically with bicalutimide to inhibit prostate cancer cell growth. Prostate. 2012 Feb;72(3):244-52. PMID: 21656835.

" Not dangerous goods.

LKT B3278 Biotin 500 mg 47.6 Water-soluble coenzyme, vitamin (B7) found in various foods, involved in synthesis of fatty acids and amino acids. Hexahydro-2-oxo-1H-thieno[3,4-d]imidazole-4-pentanoic acid Biodermatin; Coenzyme R; Vitamin H 58-85-5 ≥98% 244.31 C10H16N2O3S C1C2C(C(S1)CCCCC(=O)O)NC(=O)N2 Ambient Ambient "Soluble in water (0.2 mg/mL). Very soluble in hot water and dilute alkali. Insoluble in common organic solvents.  DMSO to 49 mg/mL.  2 M NaOH to 50 mg/mL.

 

" "Lietzan AD, St Maurice M. Functionally diverse biotin-dependent enzymes with oxaloacetate decarboxylase activity. Arch Biochem Biophys. 2014 Feb 15;544:75-86. PMID: 24184447.

 

Trippier PC. Synthetic strategies for the biotinylation of bioactive small molecules. ChemMedChem. 2013 Feb;8(2):190-203. PMID: 23303486.

 

Zempleni J, Wijeratne SS, Hassan YI. Biotin. Biofactors. 2009 Jan-Feb;35(1):36-46. PMID: 19319844.

" None Not dangerous goods.

LKT B3278 Biotin 1 g 74.8 Water-soluble coenzyme, vitamin (B7) found in various foods, involved in synthesis of fatty acids and amino acids. Hexahydro-2-oxo-1H-thieno[3,4-d]imidazole-4-pentanoic acid Biodermatin; Coenzyme R; Vitamin H 58-85-5 ≥98% 244.31 C10H16N2O3S C1C2C(C(S1)CCCCC(=O)O)NC(=O)N2 Ambient Ambient "Soluble in water (0.2 mg/mL). Very soluble in hot water and dilute alkali. Insoluble in common organic solvents.  DMSO to 49 mg/mL.  2 M NaOH to 50 mg/mL.

 

" "Lietzan AD, St Maurice M. Functionally diverse biotin-dependent enzymes with oxaloacetate decarboxylase activity. Arch Biochem Biophys. 2014 Feb 15;544:75-86. PMID: 24184447.

 

Trippier PC. Synthetic strategies for the biotinylation of bioactive small molecules. ChemMedChem. 2013 Feb;8(2):190-203. PMID: 23303486.

 

Zempleni J, Wijeratne SS, Hassan YI. Biotin. Biofactors. 2009 Jan-Feb;35(1):36-46. PMID: 19319844.

" None Not dangerous goods.

LKT B3278 Biotin 5 g 305.9 Water-soluble coenzyme, vitamin (B7) found in various foods, involved in synthesis of fatty acids and amino acids. Hexahydro-2-oxo-1H-thieno[3,4-d]imidazole-4-pentanoic acid Biodermatin; Coenzyme R; Vitamin H 58-85-5 ≥98% 244.31 C10H16N2O3S C1C2C(C(S1)CCCCC(=O)O)NC(=O)N2 Ambient Ambient "Soluble in water (0.2 mg/mL). Very soluble in hot water and dilute alkali. Insoluble in common organic solvents.  DMSO to 49 mg/mL.  2 M NaOH to 50 mg/mL.

 

" "Lietzan AD, St Maurice M. Functionally diverse biotin-dependent enzymes with oxaloacetate decarboxylase activity. Arch Biochem Biophys. 2014 Feb 15;544:75-86. PMID: 24184447.

 

Trippier PC. Synthetic strategies for the biotinylation of bioactive small molecules. ChemMedChem. 2013 Feb;8(2):190-203. PMID: 23303486.

 

Zempleni J, Wijeratne SS, Hassan YI. Biotin. Biofactors. 2009 Jan-Feb;35(1):36-46. PMID: 19319844.

" None Not dangerous goods.

LKT B3278 Biotin 10 g 543.6 Water-soluble coenzyme, vitamin (B7) found in various foods, involved in synthesis of fatty acids and amino acids. Hexahydro-2-oxo-1H-thieno[3,4-d]imidazole-4-pentanoic acid Biodermatin; Coenzyme R; Vitamin H 58-85-5 ≥98% 244.31 C10H16N2O3S C1C2C(C(S1)CCCCC(=O)O)NC(=O)N2 Ambient Ambient "Soluble in water (0.2 mg/mL). Very soluble in hot water and dilute alkali. Insoluble in common organic solvents.  DMSO to 49 mg/mL.  2 M NaOH to 50 mg/mL.

 

" "Lietzan AD, St Maurice M. Functionally diverse biotin-dependent enzymes with oxaloacetate decarboxylase activity. Arch Biochem Biophys. 2014 Feb 15;544:75-86. PMID: 24184447.

 

Trippier PC. Synthetic strategies for the biotinylation of bioactive small molecules. ChemMedChem. 2013 Feb;8(2):190-203. PMID: 23303486.

 

Zempleni J, Wijeratne SS, Hassan YI. Biotin. Biofactors. 2009 Jan-Feb;35(1):36-46. PMID: 19319844.

" None Not dangerous goods.

LKT B3320 Bifonazole 1 g 38.1 Imidazole; HMG-CoA reductase, 14-α demethylase, calmodulin inhibitor. 1-([1,1'-Biphenyl]-4-yl-phenylmethyl)-1H-imidazole Amycor; Bedriol; Mycospor; Mycosporan 60628-96-8 ≥98% 310.39 C22H18N2 C1=CC=C(C=C1)C2=CC=C(C=C2)C(C3=CC=CC=C3)N4C=CN=C4 Very lipophilic. Ambient Ambient Soluble in alcohols, DMF or DMSO. "Cheng JS, Chou CT, Liang WZ, et al. The mechanism of bifonazole-induced [Ca2+]i rises and non-Ca2+-triggered cell death in PC3 human prostate cancer cells. J Recept Signal Transduct Res. 2014 May 22:1-7. PMID: 24849495.

 

Penso J, Beitner R. Clotrimazole and bifonazole detach hexokinase from mitochondria of melanoma cells. Eur J Pharmacol. 1998 Jan 19;342(1):113-7. PMID: 9544799.

 

Hegemann L, Toso SM, Lahijani KI, et al. Direct interaction of antifungal azole-derivatives with calmodulin: a possible mechanism for their therapeutic activity. J Invest Dermatol. 1993 Mar;100(3):343-6. PMID: 8440921.

 

Berg D, Regel E, Harenberg HE, et al. Bifonazole and clotrimazole. Their mode of action and the possible reason for the fungicidal behaviour of bifonazole. Arzneimittelforschung. 1984;34(2):139-46. PMID: 6372801.

 

Kawakami K, Harada T, Yoshihashi Y, et al. Correlation between glass-forming ability and fragility of pharmaceutical compounds. J Phys Chem B. 2015 Apr 9;119(14):4873-4880. PMID: 25781503.

" Not dangerous goods.

LKT B3320 Bifonazole 5 g 95.1 Imidazole; HMG-CoA reductase, 14-α demethylase, calmodulin inhibitor. 1-([1,1'-Biphenyl]-4-yl-phenylmethyl)-1H-imidazole Amycor; Bedriol; Mycospor; Mycosporan 60628-96-8 ≥98% 310.39 C22H18N2 C1=CC=C(C=C1)C2=CC=C(C=C2)C(C3=CC=CC=C3)N4C=CN=C4 Very lipophilic. Ambient Ambient Soluble in alcohols, DMF or DMSO. "Cheng JS, Chou CT, Liang WZ, et al. The mechanism of bifonazole-induced [Ca2+]i rises and non-Ca2+-triggered cell death in PC3 human prostate cancer cells. J Recept Signal Transduct Res. 2014 May 22:1-7. PMID: 24849495.

 

Penso J, Beitner R. Clotrimazole and bifonazole detach hexokinase from mitochondria of melanoma cells. Eur J Pharmacol. 1998 Jan 19;342(1):113-7. PMID: 9544799.

 

Hegemann L, Toso SM, Lahijani KI, et al. Direct interaction of antifungal azole-derivatives with calmodulin: a possible mechanism for their therapeutic activity. J Invest Dermatol. 1993 Mar;100(3):343-6. PMID: 8440921.

 

Berg D, Regel E, Harenberg HE, et al. Bifonazole and clotrimazole. Their mode of action and the possible reason for the fungicidal behaviour of bifonazole. Arzneimittelforschung. 1984;34(2):139-46. PMID: 6372801.

 

Kawakami K, Harada T, Yoshihashi Y, et al. Correlation between glass-forming ability and fragility of pharmaceutical compounds. J Phys Chem B. 2015 Apr 9;119(14):4873-4880. PMID: 25781503.

" Not dangerous goods.

LKT B3320 Bifonazole 25 g 305.9 Imidazole; HMG-CoA reductase, 14-α demethylase, calmodulin inhibitor. 1-([1,1'-Biphenyl]-4-yl-phenylmethyl)-1H-imidazole Amycor; Bedriol; Mycospor; Mycosporan 60628-96-8 ≥98% 310.39 C22H18N2 C1=CC=C(C=C1)C2=CC=C(C=C2)C(C3=CC=CC=C3)N4C=CN=C4 Very lipophilic. Ambient Ambient Soluble in alcohols, DMF or DMSO. "Cheng JS, Chou CT, Liang WZ, et al. The mechanism of bifonazole-induced [Ca2+]i rises and non-Ca2+-triggered cell death in PC3 human prostate cancer cells. J Recept Signal Transduct Res. 2014 May 22:1-7. PMID: 24849495.

 

Penso J, Beitner R. Clotrimazole and bifonazole detach hexokinase from mitochondria of melanoma cells. Eur J Pharmacol. 1998 Jan 19;342(1):113-7. PMID: 9544799.

 

Hegemann L, Toso SM, Lahijani KI, et al. Direct interaction of antifungal azole-derivatives with calmodulin: a possible mechanism for their therapeutic activity. J Invest Dermatol. 1993 Mar;100(3):343-6. PMID: 8440921.

 

Berg D, Regel E, Harenberg HE, et al. Bifonazole and clotrimazole. Their mode of action and the possible reason for the fungicidal behaviour of bifonazole. Arzneimittelforschung. 1984;34(2):139-46. PMID: 6372801.

 

Kawakami K, Harada T, Yoshihashi Y, et al. Correlation between glass-forming ability and fragility of pharmaceutical compounds. J Phys Chem B. 2015 Apr 9;119(14):4873-4880. PMID: 25781503.

" Not dangerous goods.

LKT B3324 Big Endothelin-1 (1-38), human 0.5 mg 612.4 Endogenous vasoconstrictive peptide, endothelin-1 precursor; ET-A/B/C agonist. 124363-98-0 ≥95% 4282.96 C189H282N48O56S5 Ambient -20°C "Lawrence E, Brain SD. Big endothelin-1 and big endothelin-3 are constrictor agents in the microvasculature: evidence for the local phosphoramidon-sensitive conversion of big endothelin-1. Eur J Pharmacol. 1993 Mar 23;233(2-3):243-50. PMID: 8467870.

 

Kohno M, Yasunari K, Yokokawa K, et al. Inhibition by atrial and brain natriuretic peptides of endothelin-1 secretion after stimulation with angiotensin II and thrombin of cultured human endothelial cells. J Clin Invest. 1991 Jun;87(6):1999-2004. PMID: 1645748.

"

LKT B3324 Big Endothelin-1 (1-38), human 1 mg 1041 Endogenous vasoconstrictive peptide, endothelin-1 precursor; ET-A/B/C agonist. 124363-98-0 ≥95% 4282.96 C189H282N48O56S5 Ambient -20°C "Lawrence E, Brain SD. Big endothelin-1 and big endothelin-3 are constrictor agents in the microvasculature: evidence for the local phosphoramidon-sensitive conversion of big endothelin-1. Eur J Pharmacol. 1993 Mar 23;233(2-3):243-50. PMID: 8467870.

 

Kohno M, Yasunari K, Yokokawa K, et al. Inhibition by atrial and brain natriuretic peptides of endothelin-1 secretion after stimulation with angiotensin II and thrombin of cultured human endothelial cells. J Clin Invest. 1991 Jun;87(6):1999-2004. PMID: 1645748.

"

LKT B3324 Big Endothelin-1 (1-38), human 2.5 mg 1836.1 Endogenous vasoconstrictive peptide, endothelin-1 precursor; ET-A/B/C agonist. 124363-98-0 ≥95% 4282.96 C189H282N48O56S5 Ambient -20°C "Lawrence E, Brain SD. Big endothelin-1 and big endothelin-3 are constrictor agents in the microvasculature: evidence for the local phosphoramidon-sensitive conversion of big endothelin-1. Eur J Pharmacol. 1993 Mar 23;233(2-3):243-50. PMID: 8467870.

 

Kohno M, Yasunari K, Yokokawa K, et al. Inhibition by atrial and brain natriuretic peptides of endothelin-1 secretion after stimulation with angiotensin II and thrombin of cultured human endothelial cells. J Clin Invest. 1991 Jun;87(6):1999-2004. PMID: 1645748.

"

LKT B3345 (−)-Bilobalide 5 mg 47.6 Sesquiterpene lactone found in Ginkgo; GABA-A antagonist. (5aR-(3aS,5aα,8b,8aS,9a,10aα))-9-(1,1-dimethylethyl)- 10,10a-dihydro-8,9-dihydroxy-4H,5aH,9H-furo[2,3-b]furo[3',2':2,3]cyclopenta[1,2-c]furan-2,4,7(3H,8H)- trione Bilobalide 33570-04-6 ≥98% 326.3 C15H18O8 CC(C)(C)C1(CC2C3(C14C(C(=O)OC4OC3=O)O)CC(=O)O2)O Ambient -20°C Soluble in ethanol or DMSO. "A P, V M N, S S A, et al. Bilobalide attenuates hypoxia induced oxidative stress, inflammation, and mitochondrial dysfunctions in 3T3 L1 adipocytes via its antioxidant potential. Free Radic Res. 2014 Jul 21:1-31. PMID: 25039303.

 

Goldie M, Dolan S. Bilobalide, a unique constituent of Ginkgo biloba, inhibits inflammatory pain in rats. Behav Pharmacol. 2013 Aug;24(4):298-306. PMID: 23838965.

 

Ma L, Wang S, Tai F, et al. Effects of bilobalide on anxiety, spatial learning, memory and levels of hippocampal glucocorticoid receptors in male Kunming mice. Phytomedicine. 2012 Dec 15;20(1):89-96. PMID: 23083816.

 

Defeudis FV. Bilobalide and neuroprotection. Pharmacol Res. 2002 Dec;46(6):565-8. PMID: 12457632.

" Xi Not dangerous goods.

LKT B3345 (−)-Bilobalide 10 mg 85.6 Sesquiterpene lactone found in Ginkgo; GABA-A antagonist. (5aR-(3aS,5aα,8b,8aS,9a,10aα))-9-(1,1-dimethylethyl)- 10,10a-dihydro-8,9-dihydroxy-4H,5aH,9H-furo[2,3-b]furo[3',2':2,3]cyclopenta[1,2-c]furan-2,4,7(3H,8H)- trione Bilobalide 33570-04-6 ≥98% 326.3 C15H18O8 CC(C)(C)C1(CC2C3(C14C(C(=O)OC4OC3=O)O)CC(=O)O2)O Ambient -20°C Soluble in ethanol or DMSO. "A P, V M N, S S A, et al. Bilobalide attenuates hypoxia induced oxidative stress, inflammation, and mitochondrial dysfunctions in 3T3 L1 adipocytes via its antioxidant potential. Free Radic Res. 2014 Jul 21:1-31. PMID: 25039303.

 

Goldie M, Dolan S. Bilobalide, a unique constituent of Ginkgo biloba, inhibits inflammatory pain in rats. Behav Pharmacol. 2013 Aug;24(4):298-306. PMID: 23838965.

 

Ma L, Wang S, Tai F, et al. Effects of bilobalide on anxiety, spatial learning, memory and levels of hippocampal glucocorticoid receptors in male Kunming mice. Phytomedicine. 2012 Dec 15;20(1):89-96. PMID: 23083816.

 

Defeudis FV. Bilobalide and neuroprotection. Pharmacol Res. 2002 Dec;46(6):565-8. PMID: 12457632.

" Xi Not dangerous goods.

LKT B3345 (−)-Bilobalide 25 mg 197.1 Sesquiterpene lactone found in Ginkgo; GABA-A antagonist. (5aR-(3aS,5aα,8b,8aS,9a,10aα))-9-(1,1-dimethylethyl)- 10,10a-dihydro-8,9-dihydroxy-4H,5aH,9H-furo[2,3-b]furo[3',2':2,3]cyclopenta[1,2-c]furan-2,4,7(3H,8H)- trione Bilobalide 33570-04-6 ≥98% 326.3 C15H18O8 CC(C)(C)C1(CC2C3(C14C(C(=O)OC4OC3=O)O)CC(=O)O2)O Ambient -20°C Soluble in ethanol or DMSO. "A P, V M N, S S A, et al. Bilobalide attenuates hypoxia induced oxidative stress, inflammation, and mitochondrial dysfunctions in 3T3 L1 adipocytes via its antioxidant potential. Free Radic Res. 2014 Jul 21:1-31. PMID: 25039303.

 

Goldie M, Dolan S. Bilobalide, a unique constituent of Ginkgo biloba, inhibits inflammatory pain in rats. Behav Pharmacol. 2013 Aug;24(4):298-306. PMID: 23838965.

 

Ma L, Wang S, Tai F, et al. Effects of bilobalide on anxiety, spatial learning, memory and levels of hippocampal glucocorticoid receptors in male Kunming mice. Phytomedicine. 2012 Dec 15;20(1):89-96. PMID: 23083816.

 

Defeudis FV. Bilobalide and neuroprotection. Pharmacol Res. 2002 Dec;46(6):565-8. PMID: 12457632.

" Xi Not dangerous goods.

LKT B3346 Brain Injury-derived Neurotrophic Peptide (3) 1 mg 180 Neuroprotective peptide. BINP ≥98% 1388.58 C62H101N17O19 Ambient -20°C "Hama T, Maruyama M, Katoh-Semba R, et al. Identification and molecular cloning of a novel brain-specific receptor protein that binds to brain injury-derived neurotrophic peptide. Possible role for neuronal survival. J Biol Chem. 2001 Aug 24;276(34):31929-35. PMID: 11399754.

 

Hama T, Murayama M, Kato R, et al. Amphiphilic helix is essential for the activity of brain injury-derived neurotrophic peptide (BINP). FEBS Lett. 1996 Nov 4;396(2-3):143-6. PMID: 8914976.

"

LKT B3346 Brain Injury-derived Neurotrophic Peptide (3) 2 mg 306.1 Neuroprotective peptide. BINP ≥98% 1388.58 C62H101N17O19 Ambient -20°C "Hama T, Maruyama M, Katoh-Semba R, et al. Identification and molecular cloning of a novel brain-specific receptor protein that binds to brain injury-derived neurotrophic peptide. Possible role for neuronal survival. J Biol Chem. 2001 Aug 24;276(34):31929-35. PMID: 11399754.

 

Hama T, Murayama M, Kato R, et al. Amphiphilic helix is essential for the activity of brain injury-derived neurotrophic peptide (BINP). FEBS Lett. 1996 Nov 4;396(2-3):143-6. PMID: 8914976.

"

LKT B3346 Brain Injury-derived Neurotrophic Peptide (3) 5 mg 540 Neuroprotective peptide. BINP ≥98% 1388.58 C62H101N17O19 Ambient -20°C "Hama T, Maruyama M, Katoh-Semba R, et al. Identification and molecular cloning of a novel brain-specific receptor protein that binds to brain injury-derived neurotrophic peptide. Possible role for neuronal survival. J Biol Chem. 2001 Aug 24;276(34):31929-35. PMID: 11399754.

 

Hama T, Murayama M, Kato R, et al. Amphiphilic helix is essential for the activity of brain injury-derived neurotrophic peptide (BINP). FEBS Lett. 1996 Nov 4;396(2-3):143-6. PMID: 8914976.

"

LKT B3358 Biochanin A 100 mg 48 Phytoestrogen, flavonoid found in clover, soy, and alfalfa; potential PPARα and PPARγ agonist. 4'-Methylgenistein; Biochanin 491-80-5 ≥98% 284.27 C16H12O5 COC1=CC=C(C=C1)C2=COC3=CC(=CC(=C3C2=O)O)O Ambient 4°C Soluble in acetone. "Wang L, Waltenberger B, Pferschy-Wenzig EM, et al. Natural product agonists of peroxisome proliferator-activated receptor gamma (PPARγ): a review. Biochem Pharmacol. 2014 Jul 30. [Epub ahead of print]. PMID: 25083916.

 

Biradar SM, Joshi H, Chheda TK. Biochanin-A ameliorates behavioural and neurochemical derangements in cognitive-deficit mice for the betterment of Alzheimer's disease. Hum Exp Toxicol. 2014 Apr;33(4):369-82. PMID: 23900307.

 

Bhardwaj V, Tadinada SM, Jain A, et al. Biochanin A reduces pancreatic cancer survival and progression. Anticancer Drugs. 2014 Mar;25(3):296-302. PMID: 24201306.

 

Nynca A, Swigonska S, Piasecka J, et al. Biochanin A affects steroidogenesis and estrogen receptor-β expression in porcine granulosa cells. Theriogenology. 2013 Oct 15;80(7):821-8. PMID: 23953692.

 

Su SJ, Yeh YT, Su SH, et al. Biochanin a promotes osteogenic but inhibits adipogenic differentiation: evidence with primary adipose-derived stem cells. Evid Based Complement Alternat Med. 2013;2013:846039. PMID: 23843885.

 

Sithisarn P, Michaelis M, Schubert-Zsilavecz M, et al. Differential antiviral and anti-inflammatory mechanisms of the flavonoids biochanin A and baicalein in H5N1 influenza A virus-infected cells. Antiviral Res. 2013 Jan;97(1):41-8. PMID: 23098745.

" Not dangerous goods.

LKT B3358 Biochanin A 250 mg 87.4 Phytoestrogen, flavonoid found in clover, soy, and alfalfa; potential PPARα and PPARγ agonist. 4'-Methylgenistein; Biochanin 491-80-5 ≥98% 284.27 C16H12O5 COC1=CC=C(C=C1)C2=COC3=CC(=CC(=C3C2=O)O)O Ambient 4°C Soluble in acetone. "Wang L, Waltenberger B, Pferschy-Wenzig EM, et al. Natural product agonists of peroxisome proliferator-activated receptor gamma (PPARγ): a review. Biochem Pharmacol. 2014 Jul 30. [Epub ahead of print]. PMID: 25083916.

 

Biradar SM, Joshi H, Chheda TK. Biochanin-A ameliorates behavioural and neurochemical derangements in cognitive-deficit mice for the betterment of Alzheimer's disease. Hum Exp Toxicol. 2014 Apr;33(4):369-82. PMID: 23900307.

 

Bhardwaj V, Tadinada SM, Jain A, et al. Biochanin A reduces pancreatic cancer survival and progression. Anticancer Drugs. 2014 Mar;25(3):296-302. PMID: 24201306.

 

Nynca A, Swigonska S, Piasecka J, et al. Biochanin A affects steroidogenesis and estrogen receptor-β expression in porcine granulosa cells. Theriogenology. 2013 Oct 15;80(7):821-8. PMID: 23953692.

 

Su SJ, Yeh YT, Su SH, et al. Biochanin a promotes osteogenic but inhibits adipogenic differentiation: evidence with primary adipose-derived stem cells. Evid Based Complement Alternat Med. 2013;2013:846039. PMID: 23843885.

 

Sithisarn P, Michaelis M, Schubert-Zsilavecz M, et al. Differential antiviral and anti-inflammatory mechanisms of the flavonoids biochanin A and baicalein in H5N1 influenza A virus-infected cells. Antiviral Res. 2013 Jan;97(1):41-8. PMID: 23098745.

" Not dangerous goods.

LKT B3358 Biochanin A 1 g 254.8 Phytoestrogen, flavonoid found in clover, soy, and alfalfa; potential PPARα and PPARγ agonist. 4'-Methylgenistein; Biochanin 491-80-5 ≥98% 284.27 C16H12O5 COC1=CC=C(C=C1)C2=COC3=CC(=CC(=C3C2=O)O)O Ambient 4°C Soluble in acetone. "Wang L, Waltenberger B, Pferschy-Wenzig EM, et al. Natural product agonists of peroxisome proliferator-activated receptor gamma (PPARγ): a review. Biochem Pharmacol. 2014 Jul 30. [Epub ahead of print]. PMID: 25083916.

 

Biradar SM, Joshi H, Chheda TK. Biochanin-A ameliorates behavioural and neurochemical derangements in cognitive-deficit mice for the betterment of Alzheimer's disease. Hum Exp Toxicol. 2014 Apr;33(4):369-82. PMID: 23900307.

 

Bhardwaj V, Tadinada SM, Jain A, et al. Biochanin A reduces pancreatic cancer survival and progression. Anticancer Drugs. 2014 Mar;25(3):296-302. PMID: 24201306.

 

Nynca A, Swigonska S, Piasecka J, et al. Biochanin A affects steroidogenesis and estrogen receptor-β expression in porcine granulosa cells. Theriogenology. 2013 Oct 15;80(7):821-8. PMID: 23953692.

 

Su SJ, Yeh YT, Su SH, et al. Biochanin a promotes osteogenic but inhibits adipogenic differentiation: evidence with primary adipose-derived stem cells. Evid Based Complement Alternat Med. 2013;2013:846039. PMID: 23843885.

 

Sithisarn P, Michaelis M, Schubert-Zsilavecz M, et al. Differential antiviral and anti-inflammatory mechanisms of the flavonoids biochanin A and baicalein in H5N1 influenza A virus-infected cells. Antiviral Res. 2013 Jan;97(1):41-8. PMID: 23098745.

" Not dangerous goods.

LKT B3374 Bisacodyl 10 g 67.9 Diphenylmethane derivative, stimulates colonic muscle contractions; Na+/K+ ATPase inhibitor. 4,4'-(2-Pyridylmethylene)-bisphenol diacetate Bicol; Broxalax; Contalax; DAMP; Dulrolax; Endokolat; Laxadin; Laxorex; Perilax; Telemin; Ulcolax 603-50-9 ≥98% 361.39 C22H19NO4 CC(=O)OC1=CC=C(C=C1)C(C2=CC=C(C=C2)OC(=O)C)C3=CC=CC=N3 Ambient 4°C Soluble in acids, acetone, propylene glycol and other organic solvents. Ethanol (4.5 mg/mL). Practically insoluble in water and alkaline solutions. "Ikarashi N, Baba K, Ushiki T, et al. The laxative effect of bisacodyl is attributable to decreased aquaporin-3 expression in the colon induced by increased PGE2 secretion from macrophages. Am J Physiol Gastrointest Liver Physiol. 2011 Nov;301(5):G887-95.PMID: 21868635.

 

Manabe N, Cremonini F, Camilleri M, et al. Effects of bisacodyl on ascending colon emptying and overall colonic transit in healthy volunteers. Aliment Pharmacol Ther. 2009 Nov 1;30(9):930-6. PMID: 19678812.

 

Beubler E, Schirgi-Degen A. Stimulation of enterocyte protein kinase C by laxatives in-vitro. J Pharm Pharmacol. 1993 Jan;45(1):59-62. PMID: 8094448.

" Xi Not dangerous goods.

LKT B3374 Bisacodyl 25 g 115.5 Diphenylmethane derivative, stimulates colonic muscle contractions; Na+/K+ ATPase inhibitor. 4,4'-(2-Pyridylmethylene)-bisphenol diacetate Bicol; Broxalax; Contalax; DAMP; Dulrolax; Endokolat; Laxadin; Laxorex; Perilax; Telemin; Ulcolax 603-50-9 ≥98% 361.39 C22H19NO4 CC(=O)OC1=CC=C(C=C1)C(C2=CC=C(C=C2)OC(=O)C)C3=CC=CC=N3 Ambient 4°C Soluble in acids, acetone, propylene glycol and other organic solvents. Ethanol (4.5 mg/mL). Practically insoluble in water and alkaline solutions. "Ikarashi N, Baba K, Ushiki T, et al. The laxative effect of bisacodyl is attributable to decreased aquaporin-3 expression in the colon induced by increased PGE2 secretion from macrophages. Am J Physiol Gastrointest Liver Physiol. 2011 Nov;301(5):G887-95.PMID: 21868635.

 

Manabe N, Cremonini F, Camilleri M, et al. Effects of bisacodyl on ascending colon emptying and overall colonic transit in healthy volunteers. Aliment Pharmacol Ther. 2009 Nov 1;30(9):930-6. PMID: 19678812.

 

Beubler E, Schirgi-Degen A. Stimulation of enterocyte protein kinase C by laxatives in-vitro. J Pharm Pharmacol. 1993 Jan;45(1):59-62. PMID: 8094448.

" Xi Not dangerous goods.

LKT B3458 Biopterin 5 mg 47.6 Endogenous pterin coenzyme required for release of neurotransmitters and NO. 2-Amino-6-[(1R,2S)-1,2-dihydroxypropyl]-4(1H)- pteridinone Pterin HB2, L-Erythro-Biopterin, L-Biopterin. 22150-76-1 ≥98% 237.22 C9H11N5O3 CC(C(C1=CN=C2C(=N1)C(=O)N=C(N2)N)O)O Ambient -20°C Soluble in alcohol, ether, acetone, or benzene. "Longo N. Disorders of biopterin metabolism. J Inherit Metab Dis. 2009 Jun;32(3):333-42. Erratum in: J Inherit Metab Dis. 2009 Jun;32(3):457. PMID: 19234759.

 

Li HY, Yao YM, Shi ZG. The biological effect of tetrahydrobiopterin and its potential role in sepsis. Sheng Li Ke Xue Jin Zhan. 1999 Oct;30(4):303-8. PMID: 12532822.

" Xi Not dangerous goods.

LKT B3458 Biopterin 10 mg 84.3 Endogenous pterin coenzyme required for release of neurotransmitters and NO. 2-Amino-6-[(1R,2S)-1,2-dihydroxypropyl]-4(1H)- pteridinone Pterin HB2, L-Erythro-Biopterin, L-Biopterin. 22150-76-1 ≥98% 237.22 C9H11N5O3 CC(C(C1=CN=C2C(=N1)C(=O)N=C(N2)N)O)O Ambient -20°C Soluble in alcohol, ether, acetone, or benzene. "Longo N. Disorders of biopterin metabolism. J Inherit Metab Dis. 2009 Jun;32(3):333-42. Erratum in: J Inherit Metab Dis. 2009 Jun;32(3):457. PMID: 19234759.

 

Li HY, Yao YM, Shi ZG. The biological effect of tetrahydrobiopterin and its potential role in sepsis. Sheng Li Ke Xue Jin Zhan. 1999 Oct;30(4):303-8. PMID: 12532822.

" Xi Not dangerous goods.

LKT B3458 Biopterin 25 mg 192.9 Endogenous pterin coenzyme required for release of neurotransmitters and NO. 2-Amino-6-[(1R,2S)-1,2-dihydroxypropyl]-4(1H)- pteridinone Pterin HB2, L-Erythro-Biopterin, L-Biopterin. 22150-76-1 ≥98% 237.22 C9H11N5O3 CC(C(C1=CN=C2C(=N1)C(=O)N=C(N2)N)O)O Ambient -20°C Soluble in alcohol, ether, acetone, or benzene. "Longo N. Disorders of biopterin metabolism. J Inherit Metab Dis. 2009 Jun;32(3):333-42. Erratum in: J Inherit Metab Dis. 2009 Jun;32(3):457. PMID: 19234759.

 

Li HY, Yao YM, Shi ZG. The biological effect of tetrahydrobiopterin and its potential role in sepsis. Sheng Li Ke Xue Jin Zhan. 1999 Oct;30(4):303-8. PMID: 12532822.

" Xi Not dangerous goods.

LKT B4402 Blasticidin S Hydrochloride 25 mg 110.1 Protein translation inhibitor. 3513-03-9 ≥98% 458.5 C17H26N8O5 HCl CN(CCC(CC(=O)NC1C=CC(OC1C(=O)O)N2C=CC(=NC2=O)N)N)C(=N)N.Cl Toxic. Protect from moisture. Ambient 4°C Soluble in water. Insoluble in organic solvents. "Yoshinari T, Sakuda S, Watanabe M, et al. New metabolic pathway for converting blasticidin S in Aspergillus flavus and inhibitory activity of aflatoxin production by blasticidin S metabolites. J Agric Food Chem. 2013 Aug 21;61(33):7925-31. PMID: 23879927.

 

Svidritskiy E, Ling C, Ermolenko DN, et al. Blasticidin S inhibits translation by trapping deformed tRNA on the ribosome. Proc Natl Acad Sci U S A. 2013 Jul 23;110(30):12283-8. PMID: 23824292." T+ "UN number: 2811     Class:  6.1     Packing Group: I  

Proper shipping name:  Toxic solids, organic, n.o.s. (Blasticidine S hydrochloride)

Marine pollutant:  No"

LKT B4402 Blasticidin S Hydrochloride 50 mg 188.8 Protein translation inhibitor. 3513-03-9 ≥98% 458.5 C17H26N8O5 HCl CN(CCC(CC(=O)NC1C=CC(OC1C(=O)O)N2C=CC(=NC2=O)N)N)C(=N)N.Cl Toxic. Protect from moisture. Ambient 4°C Soluble in water. Insoluble in organic solvents. "Yoshinari T, Sakuda S, Watanabe M, et al. New metabolic pathway for converting blasticidin S in Aspergillus flavus and inhibitory activity of aflatoxin production by blasticidin S metabolites. J Agric Food Chem. 2013 Aug 21;61(33):7925-31. PMID: 23879927.

 

Svidritskiy E, Ling C, Ermolenko DN, et al. Blasticidin S inhibits translation by trapping deformed tRNA on the ribosome. Proc Natl Acad Sci U S A. 2013 Jul 23;110(30):12283-8. PMID: 23824292." T+ "UN number: 2811     Class:  6.1     Packing Group: I  

Proper shipping name:  Toxic solids, organic, n.o.s. (Blasticidine S hydrochloride)

Marine pollutant:  No"

LKT B4402 Blasticidin S Hydrochloride 100 mg 337.1 Protein translation inhibitor. 3513-03-9 ≥98% 458.5 C17H26N8O5 HCl CN(CCC(CC(=O)NC1C=CC(OC1C(=O)O)N2C=CC(=NC2=O)N)N)C(=N)N.Cl Toxic. Protect from moisture. Ambient 4°C Soluble in water. Insoluble in organic solvents. "Yoshinari T, Sakuda S, Watanabe M, et al. New metabolic pathway for converting blasticidin S in Aspergillus flavus and inhibitory activity of aflatoxin production by blasticidin S metabolites. J Agric Food Chem. 2013 Aug 21;61(33):7925-31. PMID: 23879927.

 

Svidritskiy E, Ling C, Ermolenko DN, et al. Blasticidin S inhibits translation by trapping deformed tRNA on the ribosome. Proc Natl Acad Sci U S A. 2013 Jul 23;110(30):12283-8. PMID: 23824292." T+ "UN number: 2811     Class:  6.1     Packing Group: I  

Proper shipping name:  Toxic solids, organic, n.o.s. (Blasticidine S hydrochloride)

Marine pollutant:  No"

LKT B4517 Bleomycin A5 Hydrochloride 5 mg 271.7 Glycopeptide, induces DNA strand breaks. Pingyangmycin hydrochloride 55658-47-4 ≥90% 1477.02 C57H89N19O21S2 HCl CC1=C(N=C(N=C1N)C(CC(=O)N)NCC(C(=O)N)N)C(=O)NC(C(C2=CN=CN2)OC3C(C(C(C(O3)CO)O)O)OC4C(C(C(C(O4)CO)O)OC(=O)N)O)C(=O)NC(C)C(C(C)C(=O)NC(C(C)O)C(=O)NCCC5=NC(=CS5)C6=NC(=CS6)C(=O)NCCCNCCCCN)O.Cl Ambient 4°C "Li P, Li DF, Guo ZT, et al. Therapeutic mechanism of bleomycin A5 on infancy hemangioma: an experimental study. Zhonghua Kou Qiang Yi Xue Za Zhi. 2013 Jan;48(1):18-22. PMID: 23534516.

 

Yang Y, Sun M, Ma Q, et al. Bleomycin A5 sclerotherapy for cervicofacial lymphatic malformations. J Vasc Surg. 2011 Jan;53(1):150-5. PMID: 20843632.

 

Liu Y, Wu F, Zou G. Electrophoresis mobility shift assay and biosensor used in studying the interaction between bleomycin A5 and DNA. Anal Chim Acta. 2007 Sep 19;599(2):310-4. PMID: 17870295.

 

Vorobjev PE, Smith JB, Pyshnaya IA, et al. Site-specific cleavage of RNA and DNA by complementary DNA--bleomycin A5 conjugates. Bioconjug Chem. 2003 Nov-Dec;14(6):1307-13. PMID: 14624648.

" Not dangerous goods.

LKT B4517 Bleomycin A5 Hydrochloride 10 mg 475.7 Glycopeptide, induces DNA strand breaks. Pingyangmycin hydrochloride 55658-47-4 ≥90% 1477.02 C57H89N19O21S2 HCl CC1=C(N=C(N=C1N)C(CC(=O)N)NCC(C(=O)N)N)C(=O)NC(C(C2=CN=CN2)OC3C(C(C(C(O3)CO)O)O)OC4C(C(C(C(O4)CO)O)OC(=O)N)O)C(=O)NC(C)C(C(C)C(=O)NC(C(C)O)C(=O)NCCC5=NC(=CS5)C6=NC(=CS6)C(=O)NCCCNCCCCN)O.Cl Ambient 4°C "Li P, Li DF, Guo ZT, et al. Therapeutic mechanism of bleomycin A5 on infancy hemangioma: an experimental study. Zhonghua Kou Qiang Yi Xue Za Zhi. 2013 Jan;48(1):18-22. PMID: 23534516.

 

Yang Y, Sun M, Ma Q, et al. Bleomycin A5 sclerotherapy for cervicofacial lymphatic malformations. J Vasc Surg. 2011 Jan;53(1):150-5. PMID: 20843632.

 

Liu Y, Wu F, Zou G. Electrophoresis mobility shift assay and biosensor used in studying the interaction between bleomycin A5 and DNA. Anal Chim Acta. 2007 Sep 19;599(2):310-4. PMID: 17870295.

 

Vorobjev PE, Smith JB, Pyshnaya IA, et al. Site-specific cleavage of RNA and DNA by complementary DNA--bleomycin A5 conjugates. Bioconjug Chem. 2003 Nov-Dec;14(6):1307-13. PMID: 14624648.

" Not dangerous goods.

LKT B4517 Bleomycin A5 Hydrochloride 25 mg 815.4 Glycopeptide, induces DNA strand breaks. Pingyangmycin hydrochloride 55658-47-4 ≥90% 1477.02 C57H89N19O21S2 HCl CC1=C(N=C(N=C1N)C(CC(=O)N)NCC(C(=O)N)N)C(=O)NC(C(C2=CN=CN2)OC3C(C(C(C(O3)CO)O)O)OC4C(C(C(C(O4)CO)O)OC(=O)N)O)C(=O)NC(C)C(C(C)C(=O)NC(C(C)O)C(=O)NCCC5=NC(=CS5)C6=NC(=CS6)C(=O)NCCCNCCCCN)O.Cl Ambient 4°C "Li P, Li DF, Guo ZT, et al. Therapeutic mechanism of bleomycin A5 on infancy hemangioma: an experimental study. Zhonghua Kou Qiang Yi Xue Za Zhi. 2013 Jan;48(1):18-22. PMID: 23534516.

 

Yang Y, Sun M, Ma Q, et al. Bleomycin A5 sclerotherapy for cervicofacial lymphatic malformations. J Vasc Surg. 2011 Jan;53(1):150-5. PMID: 20843632.

 

Liu Y, Wu F, Zou G. Electrophoresis mobility shift assay and biosensor used in studying the interaction between bleomycin A5 and DNA. Anal Chim Acta. 2007 Sep 19;599(2):310-4. PMID: 17870295.

 

Vorobjev PE, Smith JB, Pyshnaya IA, et al. Site-specific cleavage of RNA and DNA by complementary DNA--bleomycin A5 conjugates. Bioconjug Chem. 2003 Nov-Dec;14(6):1307-13. PMID: 14624648.

" Not dangerous goods.

LKT B4518 Bleomycin Sulfate 5 mg 133.2 Mixture of glycopeptide bleomycin sulfate salts, induces DNA strand breaks. Blenoxane; Blexane 9041-93-4 ≥90% 1512.63 C55H84N17O21S3 H2SO4 CC1=C(N=C(N=C1N)C(CC(=O)N)NCC(C(=O)N)N)C(=O)NC(C(C2=CN=CN2)OC3C(C(C(C(O3)CO)O)O)OC4C(C(C(C(O4)CO)O)OC(=O)N)O)C(=O)NC(C)C(C(C)C(=O)NC(C(C)O)C(=O)NCCC5=NC(=CS5)C6=NC(=CS6)C(=O)NCCC[S+](C)C)O.OS(=O)(=O)[O-] In DMSO at +4 for 2 weeks at -80 for 6 months. Ambient 4°C Soluble in water to 20 mg/mL. DMSO to 100 mg/mL. Methanol. "Ramírez-Fort MK, Au SC, Javed SA, et al. Management of cutaneous human papillomavirus infection: pharmacotherapies. Curr Probl Dermatol. 2014;45:175-85. PMID: 24643186.

 

Li P, Li DF, Guo ZT, et al. Therapeutic mechanism of bleomycin A5 on infancy hemangioma: an experimental study. Zhonghua Kou Qiang Yi Xue Za Zhi. 2013 Jan;48(1):18-22. PMID: 23534516.

 

Nguyen HT, Murray V. The DNA sequence specificity of bleomycin cleavage in telomeric sequences in human cells. J Biol Inorg Chem. 2012 Dec;17(8):1209-15. PMID: 22961398.

 

Yang Y, Sun M, Ma Q, et al. Bleomycin A5 sclerotherapy for cervicofacial lymphatic malformations. J Vasc Surg. 2011 Jan;53(1):150-5. PMID: 20843632.

 

Liu Y, Wu F, Zou G. Electrophoresis mobility shift assay and biosensor used in studying the interaction between bleomycin A5 and DNA. Anal Chim Acta. 2007 Sep 19;599(2):310-4. PMID: 17870295.

 

Vorobjev PE, Smith JB, Pyshnaya IA, et al. Site-specific cleavage of RNA and DNA by complementary DNA--bleomycin A5 conjugates. Bioconjug Chem. 2003 Nov-Dec;14(6):1307-13. PMID: 14624648.

 

Abraham AT, Lin JJ, Newton DL, et al. RNA cleavage and inhibition of protein synthesis by bleomycin. Chem Biol. 2003 Jan;10(1):45-52. PMID: 12573697.

 

Hecht SM. Bleomycin: new perspectives on the mechanism of action. J Nat Prod. 2000 Jan;63(1):158-68. PMID: 10650103.

 

Marcon L, Zhang X, Hales BF, et al. Effects of chemotherapeutic agents for testicular cancer on rat spermatogonial stem/progenitor cells. J Androl. 2011 Jul-Aug;32(4):432-443. PMID: 21088230." T Not dangerous goods.

LKT B4518 Bleomycin Sulfate 10 mg 183.4 Mixture of glycopeptide bleomycin sulfate salts, induces DNA strand breaks. Blenoxane; Blexane 9041-93-4 ≥90% 1512.63 C55H84N17O21S3 H2SO4 CC1=C(N=C(N=C1N)C(CC(=O)N)NCC(C(=O)N)N)C(=O)NC(C(C2=CN=CN2)OC3C(C(C(C(O3)CO)O)O)OC4C(C(C(C(O4)CO)O)OC(=O)N)O)C(=O)NC(C)C(C(C)C(=O)NC(C(C)O)C(=O)NCCC5=NC(=CS5)C6=NC(=CS6)C(=O)NCCC[S+](C)C)O.OS(=O)(=O)[O-] In DMSO at +4 for 2 weeks at -80 for 6 months. Ambient 4°C Soluble in water to 20 mg/mL. DMSO to 100 mg/mL. Methanol. "Ramírez-Fort MK, Au SC, Javed SA, et al. Management of cutaneous human papillomavirus infection: pharmacotherapies. Curr Probl Dermatol. 2014;45:175-85. PMID: 24643186.

 

Li P, Li DF, Guo ZT, et al. Therapeutic mechanism of bleomycin A5 on infancy hemangioma: an experimental study. Zhonghua Kou Qiang Yi Xue Za Zhi. 2013 Jan;48(1):18-22. PMID: 23534516.

 

Nguyen HT, Murray V. The DNA sequence specificity of bleomycin cleavage in telomeric sequences in human cells. J Biol Inorg Chem. 2012 Dec;17(8):1209-15. PMID: 22961398.

 

Yang Y, Sun M, Ma Q, et al. Bleomycin A5 sclerotherapy for cervicofacial lymphatic malformations. J Vasc Surg. 2011 Jan;53(1):150-5. PMID: 20843632.

 

Liu Y, Wu F, Zou G. Electrophoresis mobility shift assay and biosensor used in studying the interaction between bleomycin A5 and DNA. Anal Chim Acta. 2007 Sep 19;599(2):310-4. PMID: 17870295.

 

Vorobjev PE, Smith JB, Pyshnaya IA, et al. Site-specific cleavage of RNA and DNA by complementary DNA--bleomycin A5 conjugates. Bioconjug Chem. 2003 Nov-Dec;14(6):1307-13. PMID: 14624648.

 

Abraham AT, Lin JJ, Newton DL, et al. RNA cleavage and inhibition of protein synthesis by bleomycin. Chem Biol. 2003 Jan;10(1):45-52. PMID: 12573697.

 

Hecht SM. Bleomycin: new perspectives on the mechanism of action. J Nat Prod. 2000 Jan;63(1):158-68. PMID: 10650103.

 

Marcon L, Zhang X, Hales BF, et al. Effects of chemotherapeutic agents for testicular cancer on rat spermatogonial stem/progenitor cells. J Androl. 2011 Jul-Aug;32(4):432-443. PMID: 21088230." T Not dangerous goods.

LKT B4518 Bleomycin Sulfate 25 mg 373.7 Mixture of glycopeptide bleomycin sulfate salts, induces DNA strand breaks. Blenoxane; Blexane 9041-93-4 ≥90% 1512.63 C55H84N17O21S3 H2SO4 CC1=C(N=C(N=C1N)C(CC(=O)N)NCC(C(=O)N)N)C(=O)NC(C(C2=CN=CN2)OC3C(C(C(C(O3)CO)O)O)OC4C(C(C(C(O4)CO)O)OC(=O)N)O)C(=O)NC(C)C(C(C)C(=O)NC(C(C)O)C(=O)NCCC5=NC(=CS5)C6=NC(=CS6)C(=O)NCCC[S+](C)C)O.OS(=O)(=O)[O-] In DMSO at +4 for 2 weeks at -80 for 6 months. Ambient 4°C Soluble in water to 20 mg/mL. DMSO to 100 mg/mL. Methanol. "Ramírez-Fort MK, Au SC, Javed SA, et al. Management of cutaneous human papillomavirus infection: pharmacotherapies. Curr Probl Dermatol. 2014;45:175-85. PMID: 24643186.

 

Li P, Li DF, Guo ZT, et al. Therapeutic mechanism of bleomycin A5 on infancy hemangioma: an experimental study. Zhonghua Kou Qiang Yi Xue Za Zhi. 2013 Jan;48(1):18-22. PMID: 23534516.

 

Nguyen HT, Murray V. The DNA sequence specificity of bleomycin cleavage in telomeric sequences in human cells. J Biol Inorg Chem. 2012 Dec;17(8):1209-15. PMID: 22961398.

 

Yang Y, Sun M, Ma Q, et al. Bleomycin A5 sclerotherapy for cervicofacial lymphatic malformations. J Vasc Surg. 2011 Jan;53(1):150-5. PMID: 20843632.

 

Liu Y, Wu F, Zou G. Electrophoresis mobility shift assay and biosensor used in studying the interaction between bleomycin A5 and DNA. Anal Chim Acta. 2007 Sep 19;599(2):310-4. PMID: 17870295.

 

Vorobjev PE, Smith JB, Pyshnaya IA, et al. Site-specific cleavage of RNA and DNA by complementary DNA--bleomycin A5 conjugates. Bioconjug Chem. 2003 Nov-Dec;14(6):1307-13. PMID: 14624648.

 

Abraham AT, Lin JJ, Newton DL, et al. RNA cleavage and inhibition of protein synthesis by bleomycin. Chem Biol. 2003 Jan;10(1):45-52. PMID: 12573697.

 

Hecht SM. Bleomycin: new perspectives on the mechanism of action. J Nat Prod. 2000 Jan;63(1):158-68. PMID: 10650103.

 

Marcon L, Zhang X, Hales BF, et al. Effects of chemotherapeutic agents for testicular cancer on rat spermatogonial stem/progenitor cells. J Androl. 2011 Jul-Aug;32(4):432-443. PMID: 21088230." T Not dangerous goods.

LKT B5560 B-type Natriuretic Peptide (1-32), rat 0.5 mg 276.2 Endogenous cardiomodulatory peptide; NPR-A agonist. Brain natriuretic peptide; BNP 133448-20-1 ≥95% 3453.01 C146H239N47O44S3 CCC(C)C1C(=O)NCC(=O)NC(C(=O)NC(C(=O)NC(C(=O)NC(C(=O)NC(C(=O)NCC(=O)NC(CSSCC(C(=O)NC(C(=O)NCC(=O)NC(C(=O)NC(C(=O)NC(C(=O)NC(C(=O)NC(C(=O)N1)CCCNC(=N)N)CC(=O)O)C(C)CC)CCCCN)CCC(=O)N)CC2=CC=CC=C2)NC(=O)C(CO)NC(=O)C(CO)NC(=O)C(CO)NC(=O)C(CC3=CNC=N3)NC(=O)C(C)NC(=O)C(CCSC)NC(=O)C(CCCCN)NC(=O)C(CO)NC(=O)C(CC(=O)N)N)C(=O)NC(CC(=O)O)C(=O)NCC(=O)NC(CC(C)C)C(=O)NC(CCCNC(=N)N)C(=O)NC(CC(C)C)C(=O)NC(CC4=CC=CC=C4)C(=O)O)CC(C)C)CCCNC(=N)N)CO)C(C)C)C Ambient -20°C "García-Berrocoso T, Giralt D, Bustamante A, et al. B-type natriuretic peptides and mortality after stroke: a systematic review and meta-analysis. Neurology. 2013 Dec 3;81(23):1976-85. PMID: 24186915.

 

Polak J, Kotrc M, Wedellova Z, et al. Lipolytic effects of B-type natriuretic peptide 1-32 in adipose tissue of heart failure patients compared with healthy controls. J Am Coll Cardiol. 2011 Sep 6;58(11):1119-25. PMID: 21884948.

 

Tsuruda T, Boerrigter G, Huntley BK, et al. Brain natriuretic Peptide is produced in cardiac fibroblasts and induces matrix metalloproteinases. Circ Res. 2002 Dec 13;91(12):1127-34. PMID: 12480813.

" Not dangerous goods.

LKT B5560 B-type Natriuretic Peptide (1-32), rat 1 mg 468.2 Endogenous cardiomodulatory peptide; NPR-A agonist. Brain natriuretic peptide; BNP 133448-20-1 ≥95% 3453.01 C146H239N47O44S3 CCC(C)C1C(=O)NCC(=O)NC(C(=O)NC(C(=O)NC(C(=O)NC(C(=O)NC(C(=O)NCC(=O)NC(CSSCC(C(=O)NC(C(=O)NCC(=O)NC(C(=O)NC(C(=O)NC(C(=O)NC(C(=O)NC(C(=O)N1)CCCNC(=N)N)CC(=O)O)C(C)CC)CCCCN)CCC(=O)N)CC2=CC=CC=C2)NC(=O)C(CO)NC(=O)C(CO)NC(=O)C(CO)NC(=O)C(CC3=CNC=N3)NC(=O)C(C)NC(=O)C(CCSC)NC(=O)C(CCCCN)NC(=O)C(CO)NC(=O)C(CC(=O)N)N)C(=O)NC(CC(=O)O)C(=O)NCC(=O)NC(CC(C)C)C(=O)NC(CCCNC(=N)N)C(=O)NC(CC(C)C)C(=O)NC(CC4=CC=CC=C4)C(=O)O)CC(C)C)CCCNC(=N)N)CO)C(C)C)C Ambient -20°C "García-Berrocoso T, Giralt D, Bustamante A, et al. B-type natriuretic peptides and mortality after stroke: a systematic review and meta-analysis. Neurology. 2013 Dec 3;81(23):1976-85. PMID: 24186915.

 

Polak J, Kotrc M, Wedellova Z, et al. Lipolytic effects of B-type natriuretic peptide 1-32 in adipose tissue of heart failure patients compared with healthy controls. J Am Coll Cardiol. 2011 Sep 6;58(11):1119-25. PMID: 21884948.

 

Tsuruda T, Boerrigter G, Huntley BK, et al. Brain natriuretic Peptide is produced in cardiac fibroblasts and induces matrix metalloproteinases. Circ Res. 2002 Dec 13;91(12):1127-34. PMID: 12480813.

" Not dangerous goods.

LKT B5560 B-type Natriuretic Peptide (1-32), rat 2.5 mg 828.1 Endogenous cardiomodulatory peptide; NPR-A agonist. Brain natriuretic peptide; BNP 133448-20-1 ≥95% 3453.01 C146H239N47O44S3 CCC(C)C1C(=O)NCC(=O)NC(C(=O)NC(C(=O)NC(C(=O)NC(C(=O)NC(C(=O)NCC(=O)NC(CSSCC(C(=O)NC(C(=O)NCC(=O)NC(C(=O)NC(C(=O)NC(C(=O)NC(C(=O)NC(C(=O)N1)CCCNC(=N)N)CC(=O)O)C(C)CC)CCCCN)CCC(=O)N)CC2=CC=CC=C2)NC(=O)C(CO)NC(=O)C(CO)NC(=O)C(CO)NC(=O)C(CC3=CNC=N3)NC(=O)C(C)NC(=O)C(CCSC)NC(=O)C(CCCCN)NC(=O)C(CO)NC(=O)C(CC(=O)N)N)C(=O)NC(CC(=O)O)C(=O)NCC(=O)NC(CC(C)C)C(=O)NC(CCCNC(=N)N)C(=O)NC(CC(C)C)C(=O)NC(CC4=CC=CC=C4)C(=O)O)CC(C)C)CCCNC(=N)N)CO)C(C)C)C Ambient -20°C "García-Berrocoso T, Giralt D, Bustamante A, et al. B-type natriuretic peptides and mortality after stroke: a systematic review and meta-analysis. Neurology. 2013 Dec 3;81(23):1976-85. PMID: 24186915.

 

Polak J, Kotrc M, Wedellova Z, et al. Lipolytic effects of B-type natriuretic peptide 1-32 in adipose tissue of heart failure patients compared with healthy controls. J Am Coll Cardiol. 2011 Sep 6;58(11):1119-25. PMID: 21884948.

 

Tsuruda T, Boerrigter G, Huntley BK, et al. Brain natriuretic Peptide is produced in cardiac fibroblasts and induces matrix metalloproteinases. Circ Res. 2002 Dec 13;91(12):1127-34. PMID: 12480813.

" Not dangerous goods.

LKT B5561 B-type Natriuretic Peptide (1-32), human 0.5 mg 276.2 Endogenous cardiomodulatory peptide; NPR-A agonist. Brain natriuretic peptide; BNP 114471-18-0 ≥97% 3464.1 C143H244N50O42S4 Ambient -20°C "García-Berrocoso T, Giralt D, Bustamante A, et al. B-type natriuretic peptides and mortality after stroke: a systematic review and meta-analysis. Neurology. 2013 Dec 3;81(23):1976-85. PMID: 24186915.

 

Polak J, Kotrc M, Wedellova Z, et al. Lipolytic effects of B-type natriuretic peptide 1-32 in adipose tissue of heart failure patients compared with healthy controls. J Am Coll Cardiol. 2011 Sep 6;58(11):1119-25. PMID: 21884948.

 

Tsuruda T, Boerrigter G, Huntley BK, et al. Brain natriuretic Peptide is produced in cardiac fibroblasts and induces matrix metalloproteinases. Circ Res. 2002 Dec 13;91(12):1127-34. PMID: 12480813.

" Not dangerous goods.

LKT B5561 B-type Natriuretic Peptide (1-32), human 1 mg 468.2 Endogenous cardiomodulatory peptide; NPR-A agonist. Brain natriuretic peptide; BNP 114471-18-0 ≥97% 3464.1 C143H244N50O42S4 Ambient -20°C "García-Berrocoso T, Giralt D, Bustamante A, et al. B-type natriuretic peptides and mortality after stroke: a systematic review and meta-analysis. Neurology. 2013 Dec 3;81(23):1976-85. PMID: 24186915.

 

Polak J, Kotrc M, Wedellova Z, et al. Lipolytic effects of B-type natriuretic peptide 1-32 in adipose tissue of heart failure patients compared with healthy controls. J Am Coll Cardiol. 2011 Sep 6;58(11):1119-25. PMID: 21884948.

 

Tsuruda T, Boerrigter G, Huntley BK, et al. Brain natriuretic Peptide is produced in cardiac fibroblasts and induces matrix metalloproteinases. Circ Res. 2002 Dec 13;91(12):1127-34. PMID: 12480813.

" Not dangerous goods.

LKT B5561 B-type Natriuretic Peptide (1-32), human 2.5 mg 828.1 Endogenous cardiomodulatory peptide; NPR-A agonist. Brain natriuretic peptide; BNP 114471-18-0 ≥97% 3464.1 C143H244N50O42S4 Ambient -20°C "García-Berrocoso T, Giralt D, Bustamante A, et al. B-type natriuretic peptides and mortality after stroke: a systematic review and meta-analysis. Neurology. 2013 Dec 3;81(23):1976-85. PMID: 24186915.

 

Polak J, Kotrc M, Wedellova Z, et al. Lipolytic effects of B-type natriuretic peptide 1-32 in adipose tissue of heart failure patients compared with healthy controls. J Am Coll Cardiol. 2011 Sep 6;58(11):1119-25. PMID: 21884948.

 

Tsuruda T, Boerrigter G, Huntley BK, et al. Brain natriuretic Peptide is produced in cardiac fibroblasts and induces matrix metalloproteinases. Circ Res. 2002 Dec 13;91(12):1127-34. PMID: 12480813.

" Not dangerous goods.

LKT B5608 Boc-FAAGRK-AMC 20 mg 960 Peptide, protease substrate. ≥98% 906 C44H63N11O6 Ambient -20°C Santoni M, Amantini C, Morelli MB, et al. Pazopanib and sunitinib trigger autophagic and non-autophagic death of bladder tumour cells. Br J Cancer. 2013 Aug 20;109(4):1040-50. PMID: 23887605.

LKT B5609 Boc-GRR-AMC 20 mg 645.1 Peptide, protease substrate. ≥98% 644.7 C29H44N10O7 Ambient -20°C Santoni M, Amantini C, Morelli MB, et al. Pazopanib and sunitinib trigger autophagic and non-autophagic death of bladder tumour cells. Br J Cancer. 2013 Aug 20;109(4):1040-50. PMID: 23887605.

LKT C3263 Ciprofloxacin Hydrochloride Monohydrate 5 g 37.8 Fluoroquinolone; topoisomerase IV and bacterial DNA gyrase inhibitor. 1-cyclopropyl-6-fluoro-1,4-dihydro-4-oxo-7-(1-piperazinyl)-3- quinolinecarboxylic acid monohydrochloride CiproR; Ciflan; Floxacipron; Proxacin  86393-32-0 ≥98% 385.82 C17H18FN3O3 HCl H2O C1CC1N2C=C(C(=O)C3=CC(=C(C=C32)N4CCNCC4)F)C(=O)O.O.Cl Ambient 4°C "Soluble in water (3.5 g/100 ml), ethanol (1.6 mg/ml).

Reconstitute with suitable solvent. Aliquot and store at -20°C. Solutions should be protected from light. Reconstituted product is stable for 6 months at -20°C." "Rajendram M, Hurley KA, Foss MH, et al. Gyramides Prevent Bacterial Growth by Inhibiting DNA Gyrase and Altering Chromosome Topology. ACS Chem Biol. 2014 Apr 22. [Epub ahead of print]. PMID: 24712739.

 

Oliphant CM, Green GM. Quinolones: a comprehensive review. Am Fam Physician. 2002 Feb 1;65(3):455-64. PMID: 11858629.

 

Drlica K, Zhao X. DNA gyrase, topoisomerase IV, and the 4-quinolones. Microbiol Mol Biol Rev. 1997 Sep;61(3):377-92. PMID: 9293187.

 

Aldred KJ, McPherson SA, Wang P, et al. Drug interactions with Bacillus anthracis topoisomerase IV: biochemical basis for quinolone action and resistance. Biochemistry. 2012 Jan 10;51(1):370-381. PMID: 22126453." None Not dangerous goods.

LKT C3263 Ciprofloxacin Hydrochloride Monohydrate 25 g 104.9 Fluoroquinolone; topoisomerase IV and bacterial DNA gyrase inhibitor. 1-cyclopropyl-6-fluoro-1,4-dihydro-4-oxo-7-(1-piperazinyl)-3- quinolinecarboxylic acid monohydrochloride CiproR; Ciflan; Floxacipron; Proxacin  86393-32-0 ≥98% 385.82 C17H18FN3O3 HCl H2O C1CC1N2C=C(C(=O)C3=CC(=C(C=C32)N4CCNCC4)F)C(=O)O.O.Cl Ambient 4°C "Soluble in water (3.5 g/100 ml), ethanol (1.6 mg/ml).

Reconstitute with suitable solvent. Aliquot and store at -20°C. Solutions should be protected from light. Reconstituted product is stable for 6 months at -20°C." "Rajendram M, Hurley KA, Foss MH, et al. Gyramides Prevent Bacterial Growth by Inhibiting DNA Gyrase and Altering Chromosome Topology. ACS Chem Biol. 2014 Apr 22. [Epub ahead of print]. PMID: 24712739.

 

Oliphant CM, Green GM. Quinolones: a comprehensive review. Am Fam Physician. 2002 Feb 1;65(3):455-64. PMID: 11858629.

 

Drlica K, Zhao X. DNA gyrase, topoisomerase IV, and the 4-quinolones. Microbiol Mol Biol Rev. 1997 Sep;61(3):377-92. PMID: 9293187.

 

Aldred KJ, McPherson SA, Wang P, et al. Drug interactions with Bacillus anthracis topoisomerase IV: biochemical basis for quinolone action and resistance. Biochemistry. 2012 Jan 10;51(1):370-381. PMID: 22126453." None Not dangerous goods.

LKT B5610 Boc-PRR-AMC 20 mg 645.1 Peptide, protease substrate. ≥98% 684.8 C32H48N10O7 Ambient -20°C Santoni M, Amantini C, Morelli MB, et al. Pazopanib and sunitinib trigger autophagic and non-autophagic death of bladder tumour cells. Br J Cancer. 2013 Aug 20;109(4):1040-50. PMID: 23887605.

LKT C3263 Ciprofloxacin Hydrochloride Monohydrate 50 g 178.5 Fluoroquinolone; topoisomerase IV and bacterial DNA gyrase inhibitor. 1-cyclopropyl-6-fluoro-1,4-dihydro-4-oxo-7-(1-piperazinyl)-3- quinolinecarboxylic acid monohydrochloride CiproR; Ciflan; Floxacipron; Proxacin  86393-32-0 ≥98% 385.82 C17H18FN3O3 HCl H2O C1CC1N2C=C(C(=O)C3=CC(=C(C=C32)N4CCNCC4)F)C(=O)O.O.Cl Ambient 4°C "Soluble in water (3.5 g/100 ml), ethanol (1.6 mg/ml).

Reconstitute with suitable solvent. Aliquot and store at -20°C. Solutions should be protected from light. Reconstituted product is stable for 6 months at -20°C." "Rajendram M, Hurley KA, Foss MH, et al. Gyramides Prevent Bacterial Growth by Inhibiting DNA Gyrase and Altering Chromosome Topology. ACS Chem Biol. 2014 Apr 22. [Epub ahead of print]. PMID: 24712739.

 

Oliphant CM, Green GM. Quinolones: a comprehensive review. Am Fam Physician. 2002 Feb 1;65(3):455-64. PMID: 11858629.

 

Drlica K, Zhao X. DNA gyrase, topoisomerase IV, and the 4-quinolones. Microbiol Mol Biol Rev. 1997 Sep;61(3):377-92. PMID: 9293187.

 

Aldred KJ, McPherson SA, Wang P, et al. Drug interactions with Bacillus anthracis topoisomerase IV: biochemical basis for quinolone action and resistance. Biochemistry. 2012 Jan 10;51(1):370-381. PMID: 22126453." None Not dangerous goods.

LKT B5611 Boc-RRR-AMC 20 mg 645.1 Peptide, protease substrate. ≥98% 743.8 C33H53N13O7 Ambient -20°C Santoni M, Amantini C, Morelli MB, et al. Pazopanib and sunitinib trigger autophagic and non-autophagic death of bladder tumour cells. Br J Cancer. 2013 Aug 20;109(4):1040-50. PMID: 23887605.

LKT "B5648

" Bombesin 1 mg 48 GRP analog, found in Bombina; bombesin and GRP agonist, hERG K+ channel blocker. 2-L-glutamine-6-L-asparagine-Alytesin 31362-50-2 ≥95% 1619.86 C71H111N24O18S CC(C)CC(C(=O)NCC(=O)NC(CC(=O)N)C(=O)NC(CCC(=O)N)C(=O)NC(CC1=CNC2=CC=CC=C21)C(=O)NC(C)C(=O)NC(C(C)C)C(=O)NCC(=O)NC(CC3=CNC=N3)C(=O)NC(CC(C)C)C(=O)NC(CCSC)C(=O)N)NC(=O)C(CCCNC(=N)N)NC(=O)C(CCC(=O)N)NC(=O)C4CCC(=O)N4 Hygroscopic. Ambient -20°C Soluble in 5% acetic acid. "Zhang HP, Xiao Z, Cilz NI, et al. Bombesin facilitates GABAergic transmission and depresses epileptiform activity in the entorhinal cortex. Hippocampus. 2014 Jan;24(1):21-31. PMID: 23966303.

 

Weber HC. Regulation and signaling of human bombesin receptors and their biological effects. Curr Opin Endocrinol Diabetes Obes. 2009 Feb;16(1):66-71. PMID: 19115523.

 

Yamada K, Wada E, Wada K. Bombesin-like peptides: studies on food intake and social behaviour with receptor knock-out mice. Ann Med. 2000 Nov;32(8):519-29. PMID: 11127929.

 

Ohlsson B, Fredäng N, Axelson J. The effect of bombesin, cholecystokinin, gastrin, and their antagonists on proliferation of pancreatic cancer cell lines. Scand J Gastroenterol. 1999 Dec;34(12):1224-9. PMID: 10636070.

" Not dangerous goods.

LKT "B5648

" Bombesin 2 mg 81 GRP analog, found in Bombina; bombesin and GRP agonist, hERG K+ channel blocker. 2-L-glutamine-6-L-asparagine-Alytesin 31362-50-2 ≥95% 1619.86 C71H111N24O18S CC(C)CC(C(=O)NCC(=O)NC(CC(=O)N)C(=O)NC(CCC(=O)N)C(=O)NC(CC1=CNC2=CC=CC=C21)C(=O)NC(C)C(=O)NC(C(C)C)C(=O)NCC(=O)NC(CC3=CNC=N3)C(=O)NC(CC(C)C)C(=O)NC(CCSC)C(=O)N)NC(=O)C(CCCNC(=N)N)NC(=O)C(CCC(=O)N)NC(=O)C4CCC(=O)N4 Hygroscopic. Ambient -20°C Soluble in 5% acetic acid. "Zhang HP, Xiao Z, Cilz NI, et al. Bombesin facilitates GABAergic transmission and depresses epileptiform activity in the entorhinal cortex. Hippocampus. 2014 Jan;24(1):21-31. PMID: 23966303.

 

Weber HC. Regulation and signaling of human bombesin receptors and their biological effects. Curr Opin Endocrinol Diabetes Obes. 2009 Feb;16(1):66-71. PMID: 19115523.

 

Yamada K, Wada E, Wada K. Bombesin-like peptides: studies on food intake and social behaviour with receptor knock-out mice. Ann Med. 2000 Nov;32(8):519-29. PMID: 11127929.

 

Ohlsson B, Fredäng N, Axelson J. The effect of bombesin, cholecystokinin, gastrin, and their antagonists on proliferation of pancreatic cancer cell lines. Scand J Gastroenterol. 1999 Dec;34(12):1224-9. PMID: 10636070.

" Not dangerous goods.

LKT B5648 Bombesin 5 mg 144 GRP analog, found in Bombina; bombesin and GRP agonist, hERG K+ channel blocker. 2-L-glutamine-6-L-asparagine-Alytesin 31362-50-2 ≥95% 1619.86 C71H111N24O18S CC(C)CC(C(=O)NCC(=O)NC(CC(=O)N)C(=O)NC(CCC(=O)N)C(=O)NC(CC1=CNC2=CC=CC=C21)C(=O)NC(C)C(=O)NC(C(C)C)C(=O)NCC(=O)NC(CC3=CNC=N3)C(=O)NC(CC(C)C)C(=O)NC(CCSC)C(=O)N)NC(=O)C(CCCNC(=N)N)NC(=O)C(CCC(=O)N)NC(=O)C4CCC(=O)N4 Hygroscopic. Ambient -20°C Soluble in 5% acetic acid. "Zhang HP, Xiao Z, Cilz NI, et al. Bombesin facilitates GABAergic transmission and depresses epileptiform activity in the entorhinal cortex. Hippocampus. 2014 Jan;24(1):21-31. PMID: 23966303.

 

Weber HC. Regulation and signaling of human bombesin receptors and their biological effects. Curr Opin Endocrinol Diabetes Obes. 2009 Feb;16(1):66-71. PMID: 19115523.

 

Yamada K, Wada E, Wada K. Bombesin-like peptides: studies on food intake and social behaviour with receptor knock-out mice. Ann Med. 2000 Nov;32(8):519-29. PMID: 11127929.

 

Ohlsson B, Fredäng N, Axelson J. The effect of bombesin, cholecystokinin, gastrin, and their antagonists on proliferation of pancreatic cancer cell lines. Scand J Gastroenterol. 1999 Dec;34(12):1224-9. PMID: 10636070.

" Not dangerous goods.

LKT C4658 Clopidogrel Sulfate 500 mg 115.5 Thienopyridine; P2Y12 antagonist. (αS)-α-(2-Chlorophenyl-6,7-dihydrothieno[3,2-c]- pyridine-5(4H)-acetic acid methyl ester Clopidogrel hydrogen sulfate; Plavix 135046-48-9 ≥98% 419.9 C16H16ClNO2S H2SO4 COC(=O)C(C1=CC=CC=C1Cl)N2CCC3=C(C2)C=CS3.OS(=O)(=O)O Ambient Ambient Soluble in water (84mg/mL), methanol, ethanol (84mg/mL), and DMSO(84mg/mL) "Thomas MR, Storey RF. Impact of aspirin dosing on the effects of P2Y12 inhibition in patients with acute coronary syndromes. J Cardiovasc Transl Res. 2014 Feb;7(1):19-28. PMID: 24309957.

 

Ferri N, Corsini A, Bellosta S. Pharmacology of the new P2Y12 receptor inhibitors: insights on pharmacokinetic and pharmacodynamic properties. Drugs. 2013 Oct;73(15):1681-709. PMID: 24114622.

 

Sato Y, Miyashita A, Iwatsubo T, Usui T. Conclusive identification of the oxybutynin-hydrolyzing enzyme in human liver. Drug Metab Dispos. 2012 May;40(5):902-906. PMID: 22293119." Not dangerous goods.

LKT C4658 Clopidogrel Sulfate 1 g 196.8 Thienopyridine; P2Y12 antagonist. (αS)-α-(2-Chlorophenyl-6,7-dihydrothieno[3,2-c]- pyridine-5(4H)-acetic acid methyl ester Clopidogrel hydrogen sulfate; Plavix 135046-48-9 ≥98% 419.9 C16H16ClNO2S H2SO4 COC(=O)C(C1=CC=CC=C1Cl)N2CCC3=C(C2)C=CS3.OS(=O)(=O)O Ambient Ambient Soluble in water (84mg/mL), methanol, ethanol (84mg/mL), and DMSO(84mg/mL) "Thomas MR, Storey RF. Impact of aspirin dosing on the effects of P2Y12 inhibition in patients with acute coronary syndromes. J Cardiovasc Transl Res. 2014 Feb;7(1):19-28. PMID: 24309957.

 

Ferri N, Corsini A, Bellosta S. Pharmacology of the new P2Y12 receptor inhibitors: insights on pharmacokinetic and pharmacodynamic properties. Drugs. 2013 Oct;73(15):1681-709. PMID: 24114622.

 

Sato Y, Miyashita A, Iwatsubo T, Usui T. Conclusive identification of the oxybutynin-hydrolyzing enzyme in human liver. Drug Metab Dispos. 2012 May;40(5):902-906. PMID: 22293119." Not dangerous goods.

LKT B5649 [Tyr4]-Bombesin 1 mg 60 GRP analog, found in Bombina; bombesin and GRP agonist, hERG K+ channel blocker. ≥95% 1669.9 C74H108N24O19S Ambient -20°C "Zhang HP, Xiao Z, Cilz NI, et al. Bombesin facilitates GABAergic transmission and depresses epileptiform activity in the entorhinal cortex. Hippocampus. 2014 Jan;24(1):21-31. PMID: 23966303.

 

Okarvi SM, Jammaz IA. Preparation and evaluation of bombesin peptide derivatives as potential tumor imaging agents: effects of structure and composition of amino acid sequence on in vitro and in vivo characteristics. Nucl Med Biol. 2012 Aug;39(6):795-804. PMID: 22381782.

 

Assimakopoulos SF, Tsamandas AC, Alexandris IH, et al. Stimulation of oval cell and hepatocyte proliferation by exogenous bombesin and neurotensin in partially hepatectomized rats. World J Gastrointest Pathophysiol. 2011 Dec 15;2(6):146-54. PMID: 22180848.

 

Zogovic B, Pilowsky PM. Intrathecal bombesin is sympathoexcitatory and pressor in rat. Am J Physiol Regul Integr Comp Physiol. 2011 Nov;301(5):R1486-94. PMID: 21849634.

" Not dangerous goods.

LKT B5649 [Tyr4]-Bombesin 2 mg 101.9 GRP analog, found in Bombina; bombesin and GRP agonist, hERG K+ channel blocker. ≥95% 1669.9 C74H108N24O19S Ambient -20°C "Zhang HP, Xiao Z, Cilz NI, et al. Bombesin facilitates GABAergic transmission and depresses epileptiform activity in the entorhinal cortex. Hippocampus. 2014 Jan;24(1):21-31. PMID: 23966303.

 

Okarvi SM, Jammaz IA. Preparation and evaluation of bombesin peptide derivatives as potential tumor imaging agents: effects of structure and composition of amino acid sequence on in vitro and in vivo characteristics. Nucl Med Biol. 2012 Aug;39(6):795-804. PMID: 22381782.

 

Assimakopoulos SF, Tsamandas AC, Alexandris IH, et al. Stimulation of oval cell and hepatocyte proliferation by exogenous bombesin and neurotensin in partially hepatectomized rats. World J Gastrointest Pathophysiol. 2011 Dec 15;2(6):146-54. PMID: 22180848.

 

Zogovic B, Pilowsky PM. Intrathecal bombesin is sympathoexcitatory and pressor in rat. Am J Physiol Regul Integr Comp Physiol. 2011 Nov;301(5):R1486-94. PMID: 21849634.

" Not dangerous goods.

LKT B5649 [Tyr4]-Bombesin 5 mg 180 GRP analog, found in Bombina; bombesin and GRP agonist, hERG K+ channel blocker. ≥95% 1669.9 C74H108N24O19S Ambient -20°C "Zhang HP, Xiao Z, Cilz NI, et al. Bombesin facilitates GABAergic transmission and depresses epileptiform activity in the entorhinal cortex. Hippocampus. 2014 Jan;24(1):21-31. PMID: 23966303.

 

Okarvi SM, Jammaz IA. Preparation and evaluation of bombesin peptide derivatives as potential tumor imaging agents: effects of structure and composition of amino acid sequence on in vitro and in vivo characteristics. Nucl Med Biol. 2012 Aug;39(6):795-804. PMID: 22381782.

 

Assimakopoulos SF, Tsamandas AC, Alexandris IH, et al. Stimulation of oval cell and hepatocyte proliferation by exogenous bombesin and neurotensin in partially hepatectomized rats. World J Gastrointest Pathophysiol. 2011 Dec 15;2(6):146-54. PMID: 22180848.

 

Zogovic B, Pilowsky PM. Intrathecal bombesin is sympathoexcitatory and pressor in rat. Am J Physiol Regul Integr Comp Physiol. 2011 Nov;301(5):R1486-94. PMID: 21849634.

" Not dangerous goods.

LKT C4658 Clopidogrel Sulfate 5 g 866.4 Thienopyridine; P2Y12 antagonist. (αS)-α-(2-Chlorophenyl-6,7-dihydrothieno[3,2-c]- pyridine-5(4H)-acetic acid methyl ester Clopidogrel hydrogen sulfate; Plavix 135046-48-9 ≥98% 419.9 C16H16ClNO2S H2SO4 COC(=O)C(C1=CC=CC=C1Cl)N2CCC3=C(C2)C=CS3.OS(=O)(=O)O Ambient Ambient Soluble in water (84mg/mL), methanol, ethanol (84mg/mL), and DMSO(84mg/mL) "Thomas MR, Storey RF. Impact of aspirin dosing on the effects of P2Y12 inhibition in patients with acute coronary syndromes. J Cardiovasc Transl Res. 2014 Feb;7(1):19-28. PMID: 24309957.

 

Ferri N, Corsini A, Bellosta S. Pharmacology of the new P2Y12 receptor inhibitors: insights on pharmacokinetic and pharmacodynamic properties. Drugs. 2013 Oct;73(15):1681-709. PMID: 24114622.

 

Sato Y, Miyashita A, Iwatsubo T, Usui T. Conclusive identification of the oxybutynin-hydrolyzing enzyme in human liver. Drug Metab Dispos. 2012 May;40(5):902-906. PMID: 22293119." Not dangerous goods.

LKT B5753 Bongkrekic Acid 100 µg 433.1 Respiratory toxin, mitochondrial permeability transition inhibitor. 3-Carboxymethyl-17-methoxy-6,18,21-trimethyldocosa-2,4,8,12,14,18,20-heptaenedioic acid Bongkrek acid 11076-19-0 ≥98% 486.6 C28H38O7 CC(CC=CCCC=CC=CCC(C(=CC=C(C)C(=O)O)C)OC)C=CC(=CC(=O)O)CC(=O)O Protect from light. Ambient -20°C Soluble as 2N in NH4OH. "Nolly MB, Caldiz CI, Yeves AM, et al. The signaling pathway for aldosterone-induced mitochondrial production of superoxide anion in the myocardium. J Mol Cell Cardiol. 2014 Feb;67:60-8. PMID: 24355174.

 

Rey M, Forest E, Pelosi L. Exploring the conformational dynamics of the bovine ADP/ATP carrier in mitochondria. Biochemistry. 2012 Dec 4;51(48):9727-35. PMID: 23136955.

" Not dangerous goods.

LKT C1630 Cefoperazone Sodium 1 g 67.9 β-lactam cephalosporin; penicillin binding protein inhibitor, mammalian mRNA splicing inhibitor. (6R,7R)-7-[[(2R)-[[(4-Ethyl-2,3-dioxo-1-piperazinyl)- carbonyl]amino](4-hydroxyphenyl)acetyl]amino]-3- [[(1-methyl-1H-tetrazol-5-yl)thio]methyl]-8-oxo-5- thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid sodium salt Bioperazone; Cefazone; Cefobis; Cefoneg; Farecef; Novobiocyl; Perocef 62893-20-3 ≥98% 667.65 C25H26N9NaO8S2 CCN1CCN(C(=O)C1=O)C(=O)NC(C2=CC=C(C=C2)O)C(=O)NC3C4N(C3=O)C(=C(CS4)CSC5=NN=NN5C)C(=O)[O-].[Na+] Stable at pH 4.0-7.0, slightly unstable in acid, very unstable in base. Ambient -20°C Soluble in water to 75 mM. "Aukema KG, Chohan KK, Plourde GL, et al. Small molecule inhibitors of yeast pre-mRNA splicing. ACS Chem Biol. 2009 Sep 18;4(9):759-68. PMID: 19634919.

 

Mohanty S, Singhal R, Sood S, et al. Comparative in vitro activity of beta-lactam/beta-lactamase inhibitor combinations against gram negative bacteria. Indian J Med Res. 2005 Nov;122(5):425-8. PMID: 16456257.

 

Yotsuji A, Mitsuyama J, Hori R, et al. Mechanism of action of cephalosporins and resistance caused by decreased affinity for penicillin-binding proteins in Bacteroides fragilis. Antimicrob Agents Chemother. 1988 Dec;32(12):1848-53. PMID: 3266730.

" Not dangerous goods.

LKT C1630 Cefoperazone Sodium 5 g 224.3 β-lactam cephalosporin; penicillin binding protein inhibitor, mammalian mRNA splicing inhibitor. (6R,7R)-7-[[(2R)-[[(4-Ethyl-2,3-dioxo-1-piperazinyl)- carbonyl]amino](4-hydroxyphenyl)acetyl]amino]-3- [[(1-methyl-1H-tetrazol-5-yl)thio]methyl]-8-oxo-5- thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid sodium salt Bioperazone; Cefazone; Cefobis; Cefoneg; Farecef; Novobiocyl; Perocef 62893-20-3 ≥98% 667.65 C25H26N9NaO8S2 CCN1CCN(C(=O)C1=O)C(=O)NC(C2=CC=C(C=C2)O)C(=O)NC3C4N(C3=O)C(=C(CS4)CSC5=NN=NN5C)C(=O)[O-].[Na+] Stable at pH 4.0-7.0, slightly unstable in acid, very unstable in base. Ambient -20°C Soluble in water to 75 mM. "Aukema KG, Chohan KK, Plourde GL, et al. Small molecule inhibitors of yeast pre-mRNA splicing. ACS Chem Biol. 2009 Sep 18;4(9):759-68. PMID: 19634919.

 

Mohanty S, Singhal R, Sood S, et al. Comparative in vitro activity of beta-lactam/beta-lactamase inhibitor combinations against gram negative bacteria. Indian J Med Res. 2005 Nov;122(5):425-8. PMID: 16456257.

 

Yotsuji A, Mitsuyama J, Hori R, et al. Mechanism of action of cephalosporins and resistance caused by decreased affinity for penicillin-binding proteins in Bacteroides fragilis. Antimicrob Agents Chemother. 1988 Dec;32(12):1848-53. PMID: 3266730.

" Not dangerous goods.

LKT O4101 Okadaic Acid 25 µg 136 Shellfish toxin produced by dinoflagellates and sea sponges; PP1 and PP2A inhibitor. 9,10-Deepithio-9,10-didehydroacanthifolicin Halochondrine A 78111-17-8 ≥98% 805 C44H68O13 CC1CCC2(CCCCO2)OC1C(C)CC(C3C(=C)C(C4C(O3)CCC5(O4)CCC(O5)C=CC(C)C6CC(=CC7(O6)C(CCC(O7)CC(C)(C(=O)O)O)O)C)O)O Protect from light. Ambient -20°C Soluble in DMSO, ethanol, or methanol. "Kamat PK, Rai S, Swarnkar S, et al. Molecular and Cellular Mechanism of Okadaic Acid (OKA)-Induced Neurotoxicity: A Novel Tool for Alzheimer's Disease Therapeutic Application. Mol Neurobiol. 2014 Apr 8. [Epub ahead of print]. PMID: 24710687.

 

Chang NC, Lin AC, Hsu CC, et al. Okadaic Acid, a Bioactive Fatty Acid from Halichondria okadai, Stimulates Lipolysis in Rat Adipocytes: The Pivotal Role of Perilipin Translocation. Evid Based Complement Alternat Med. 2013;2013:545739. PMID: 24319476.

 

Mori N, Ishikawa C, Uchihara JN, et al. Protein phosphatase 2A as a potential target for treatment of adult T cell leukemia. Curr Cancer Drug Targets. 2013 Oct;13(8):829-42. PMID: 24015987.

" Xi, T "UN number: 3462     Class:  6.1     Packing group:  I

Proper shipping name:  Toxins, extracted from living sources, solid, n.o.s. (Okadaic acid)

Marine pollutant:  No     Poison inhalation hazard:  No"

LKT O4101 Okadaic Acid 50 µg 228.4 Shellfish toxin produced by dinoflagellates and sea sponges; PP1 and PP2A inhibitor. 9,10-Deepithio-9,10-didehydroacanthifolicin Halochondrine A 78111-17-8 ≥98% 805 C44H68O13 CC1CCC2(CCCCO2)OC1C(C)CC(C3C(=C)C(C4C(O3)CCC5(O4)CCC(O5)C=CC(C)C6CC(=CC7(O6)C(CCC(O7)CC(C)(C(=O)O)O)O)C)O)O Protect from light. Ambient -20°C Soluble in DMSO, ethanol, or methanol. "Kamat PK, Rai S, Swarnkar S, et al. Molecular and Cellular Mechanism of Okadaic Acid (OKA)-Induced Neurotoxicity: A Novel Tool for Alzheimer's Disease Therapeutic Application. Mol Neurobiol. 2014 Apr 8. [Epub ahead of print]. PMID: 24710687.

 

Chang NC, Lin AC, Hsu CC, et al. Okadaic Acid, a Bioactive Fatty Acid from Halichondria okadai, Stimulates Lipolysis in Rat Adipocytes: The Pivotal Role of Perilipin Translocation. Evid Based Complement Alternat Med. 2013;2013:545739. PMID: 24319476.

 

Mori N, Ishikawa C, Uchihara JN, et al. Protein phosphatase 2A as a potential target for treatment of adult T cell leukemia. Curr Cancer Drug Targets. 2013 Oct;13(8):829-42. PMID: 24015987.

" Xi, T "UN number: 3462     Class:  6.1     Packing group:  I

Proper shipping name:  Toxins, extracted from living sources, solid, n.o.s. (Okadaic acid)

Marine pollutant:  No     Poison inhalation hazard:  No"

LKT O4101 Okadaic Acid 100 µg 421.4 Shellfish toxin produced by dinoflagellates and sea sponges; PP1 and PP2A inhibitor. 9,10-Deepithio-9,10-didehydroacanthifolicin Halochondrine A 78111-17-8 ≥98% 805 C44H68O13 CC1CCC2(CCCCO2)OC1C(C)CC(C3C(=C)C(C4C(O3)CCC5(O4)CCC(O5)C=CC(C)C6CC(=CC7(O6)C(CCC(O7)CC(C)(C(=O)O)O)O)C)O)O Protect from light. Ambient -20°C Soluble in DMSO, ethanol, or methanol. "Kamat PK, Rai S, Swarnkar S, et al. Molecular and Cellular Mechanism of Okadaic Acid (OKA)-Induced Neurotoxicity: A Novel Tool for Alzheimer's Disease Therapeutic Application. Mol Neurobiol. 2014 Apr 8. [Epub ahead of print]. PMID: 24710687.

 

Chang NC, Lin AC, Hsu CC, et al. Okadaic Acid, a Bioactive Fatty Acid from Halichondria okadai, Stimulates Lipolysis in Rat Adipocytes: The Pivotal Role of Perilipin Translocation. Evid Based Complement Alternat Med. 2013;2013:545739. PMID: 24319476.

 

Mori N, Ishikawa C, Uchihara JN, et al. Protein phosphatase 2A as a potential target for treatment of adult T cell leukemia. Curr Cancer Drug Targets. 2013 Oct;13(8):829-42. PMID: 24015987.

" Xi, T "UN number: 3462     Class:  6.1     Packing group:  I

Proper shipping name:  Toxins, extracted from living sources, solid, n.o.s. (Okadaic acid)

Marine pollutant:  No     Poison inhalation hazard:  No"

LKT O4101 Okadaic Acid 1 mg 2514.1 Shellfish toxin produced by dinoflagellates and sea sponges; PP1 and PP2A inhibitor. 9,10-Deepithio-9,10-didehydroacanthifolicin Halochondrine A 78111-17-8 ≥98% 805 C44H68O13 CC1CCC2(CCCCO2)OC1C(C)CC(C3C(=C)C(C4C(O3)CCC5(O4)CCC(O5)C=CC(C)C6CC(=CC7(O6)C(CCC(O7)CC(C)(C(=O)O)O)O)C)O)O Protect from light. Ambient -20°C Soluble in DMSO, ethanol, or methanol. "Kamat PK, Rai S, Swarnkar S, et al. Molecular and Cellular Mechanism of Okadaic Acid (OKA)-Induced Neurotoxicity: A Novel Tool for Alzheimer's Disease Therapeutic Application. Mol Neurobiol. 2014 Apr 8. [Epub ahead of print]. PMID: 24710687.

 

Chang NC, Lin AC, Hsu CC, et al. Okadaic Acid, a Bioactive Fatty Acid from Halichondria okadai, Stimulates Lipolysis in Rat Adipocytes: The Pivotal Role of Perilipin Translocation. Evid Based Complement Alternat Med. 2013;2013:545739. PMID: 24319476.

 

Mori N, Ishikawa C, Uchihara JN, et al. Protein phosphatase 2A as a potential target for treatment of adult T cell leukemia. Curr Cancer Drug Targets. 2013 Oct;13(8):829-42. PMID: 24015987.

" Xi, T "UN number: 3462     Class:  6.1     Packing group:  I

Proper shipping name:  Toxins, extracted from living sources, solid, n.o.s. (Okadaic acid)

Marine pollutant:  No     Poison inhalation hazard:  No"

LKT "C4559

 

" Clomiphene Citrate 1 g 43.5 Used for in vitro fertilization; FIASMA, SERM. 2-[4-(2-Chloro-1,2-diphenylethenyl)phenoxy]-N,N- diethylethanamine Clomid; Clomphid; Clostilbegyt; Dyneric; Pergotime; Serophene; Clomifene 50-41-9 ≥98% 598.09 C26H28ClNO C6H8O7  CCN(CC)CCOC1=CC=C(C=C1)C(=C(C2=CC=CC=C2)Cl)C3=CC=CC=C3.C(C(=O)O)C(CC(=O)O)(C(=O)O)O Ambient 4°C Slightly soluble in water and chloroform. Soluble in methanol. Insoluble in ether. "Amita M, Takahashi T, Tsutsumi S, et al. Molecular mechanism of the inhibition of estradiol-induced endometrial epithelial cell proliferation by clomiphene citrate. Endocrinology. 2010 Jan;151(1):394-405. PMID: 19934375.

 

Shoham Z, Schacter M, Loumaye E, et al. The luteinizing hormone surge--the final stage in ovulation induction: modern aspects of ovulation triggering. Fertil Steril. 1995 Aug;64(2):237-51. PMID: 7615097.

" Repr. Not dangerous goods.

LKT C4559 Clomiphene Citrate 5 g 122.3 Used for in vitro fertilization; FIASMA, SERM. 2-[4-(2-Chloro-1,2-diphenylethenyl)phenoxy]-N,N- diethylethanamine Clomid; Clomphid; Clostilbegyt; Dyneric; Pergotime; Serophene; Clomifene 50-41-9 ≥98% 598.09 C26H28ClNO C6H8O7  CCN(CC)CCOC1=CC=C(C=C1)C(=C(C2=CC=CC=C2)Cl)C3=CC=CC=C3.C(C(=O)O)C(CC(=O)O)(C(=O)O)O Ambient 4°C Slightly soluble in water and chloroform. Soluble in methanol. Insoluble in ether. "Amita M, Takahashi T, Tsutsumi S, et al. Molecular mechanism of the inhibition of estradiol-induced endometrial epithelial cell proliferation by clomiphene citrate. Endocrinology. 2010 Jan;151(1):394-405. PMID: 19934375.

 

Shoham Z, Schacter M, Loumaye E, et al. The luteinizing hormone surge--the final stage in ovulation induction: modern aspects of ovulation triggering. Fertil Steril. 1995 Aug;64(2):237-51. PMID: 7615097.

" Repr. Not dangerous goods.

LKT "C4559

 

" Clomiphene Citrate 10 g 184.5 Used for in vitro fertilization; FIASMA, SERM. 2-[4-(2-Chloro-1,2-diphenylethenyl)phenoxy]-N,N- diethylethanamine Clomid; Clomphid; Clostilbegyt; Dyneric; Pergotime; Serophene; Clomifene 50-41-9 ≥98% 598.09 C26H28ClNO C6H8O7  CCN(CC)CCOC1=CC=C(C=C1)C(=C(C2=CC=CC=C2)Cl)C3=CC=CC=C3.C(C(=O)O)C(CC(=O)O)(C(=O)O)O Ambient 4°C Slightly soluble in water and chloroform. Soluble in methanol. Insoluble in ether. "Amita M, Takahashi T, Tsutsumi S, et al. Molecular mechanism of the inhibition of estradiol-induced endometrial epithelial cell proliferation by clomiphene citrate. Endocrinology. 2010 Jan;151(1):394-405. PMID: 19934375.

 

Shoham Z, Schacter M, Loumaye E, et al. The luteinizing hormone surge--the final stage in ovulation induction: modern aspects of ovulation triggering. Fertil Steril. 1995 Aug;64(2):237-51. PMID: 7615097.

" Repr. Not dangerous goods.

LKT B6800 Bradykinin Triacetate 10 mg 60 Natriuretic, vasodilatory peptide; B1/2 agonist. Bradykinin triacetate salt 5979-11-3 ≥95% 1240.38 C50H73N15O11 CC(=O)O.CC(=O)O.CC(=O)O.C1CC(N(C1)C(=O)C2CCCN2C(=O)C(CCCN=C(N)N)N)C(=O)NCC(=O)NC(CC3=CC=CC=C3)C(=O)NC(CO)C(=O)N4CCCC4C(=O)NC(CC5=CC=CC=C5)C(=O)NC(CCCN=C(N)N)C(=O)O Shelf life of up to 2 years. Ambient -20°C Soluble at 25mg/mL in water. "Mamenko M, Zaika O, Pochynyuk O. Direct regulation of ENaC by bradykinin in the distal nephron. Implications for renal sodium handling. Curr Opin Nephrol Hypertens. 2014 Mar;23(2):122-9. PMID: 24378775.

 

Yu HS, Wang SW, Chang AC, et al. Bradykinin promotes vascular endothelial growth factor expression and increases angiogenesis in human prostate cancer cells. Biochem Pharmacol. 2014 Jan 15;87(2):243-53. PMID: 24225154.

 

Dong R, Xu X, Li G, et al. Bradykinin inhibits oxidative stress-induced cardiomyocytes senescence via regulating redox state. PLoS One. 2013 Oct 25;8(10):e77034. PMID: 24204728.

 

Feher A, Cassuto J, Szabo A, et al. Increased tissue angiotensin-converting enzyme activity impairs bradykinin-induced dilation of coronary arterioles in obesity. Circ J. 2013;77(7):1867-76. PMID: 23603844.

" Not dangerous goods.

LKT B6800 Bradykinin Triacetate 20 mg 101.9 Natriuretic, vasodilatory peptide; B1/2 agonist. Bradykinin triacetate salt 5979-11-3 ≥95% 1240.38 C50H73N15O11 CC(=O)O.CC(=O)O.CC(=O)O.C1CC(N(C1)C(=O)C2CCCN2C(=O)C(CCCN=C(N)N)N)C(=O)NCC(=O)NC(CC3=CC=CC=C3)C(=O)NC(CO)C(=O)N4CCCC4C(=O)NC(CC5=CC=CC=C5)C(=O)NC(CCCN=C(N)N)C(=O)O Shelf life of up to 2 years. Ambient -20°C Soluble at 25mg/mL in water. "Mamenko M, Zaika O, Pochynyuk O. Direct regulation of ENaC by bradykinin in the distal nephron. Implications for renal sodium handling. Curr Opin Nephrol Hypertens. 2014 Mar;23(2):122-9. PMID: 24378775.

 

Yu HS, Wang SW, Chang AC, et al. Bradykinin promotes vascular endothelial growth factor expression and increases angiogenesis in human prostate cancer cells. Biochem Pharmacol. 2014 Jan 15;87(2):243-53. PMID: 24225154.

 

Dong R, Xu X, Li G, et al. Bradykinin inhibits oxidative stress-induced cardiomyocytes senescence via regulating redox state. PLoS One. 2013 Oct 25;8(10):e77034. PMID: 24204728.

 

Feher A, Cassuto J, Szabo A, et al. Increased tissue angiotensin-converting enzyme activity impairs bradykinin-induced dilation of coronary arterioles in obesity. Circ J. 2013;77(7):1867-76. PMID: 23603844.

" Not dangerous goods.

LKT B6800 Bradykinin Triacetate 50 mg 180 Natriuretic, vasodilatory peptide; B1/2 agonist. Bradykinin triacetate salt 5979-11-3 ≥95% 1240.38 C50H73N15O11 CC(=O)O.CC(=O)O.CC(=O)O.C1CC(N(C1)C(=O)C2CCCN2C(=O)C(CCCN=C(N)N)N)C(=O)NCC(=O)NC(CC3=CC=CC=C3)C(=O)NC(CO)C(=O)N4CCCC4C(=O)NC(CC5=CC=CC=C5)C(=O)NC(CCCN=C(N)N)C(=O)O Shelf life of up to 2 years. Ambient -20°C Soluble at 25mg/mL in water. "Mamenko M, Zaika O, Pochynyuk O. Direct regulation of ENaC by bradykinin in the distal nephron. Implications for renal sodium handling. Curr Opin Nephrol Hypertens. 2014 Mar;23(2):122-9. PMID: 24378775.

 

Yu HS, Wang SW, Chang AC, et al. Bradykinin promotes vascular endothelial growth factor expression and increases angiogenesis in human prostate cancer cells. Biochem Pharmacol. 2014 Jan 15;87(2):243-53. PMID: 24225154.

 

Dong R, Xu X, Li G, et al. Bradykinin inhibits oxidative stress-induced cardiomyocytes senescence via regulating redox state. PLoS One. 2013 Oct 25;8(10):e77034. PMID: 24204728.

 

Feher A, Cassuto J, Szabo A, et al. Increased tissue angiotensin-converting enzyme activity impairs bradykinin-induced dilation of coronary arterioles in obesity. Circ J. 2013;77(7):1867-76. PMID: 23603844.

" Not dangerous goods.

LKT B6802 Bradykinin (1-3) 5 mg 60 Natriuretic, vasodilatory peptide fragment; B1/2 agonist. 23815-91-0 ≥95% 368.4 C16H28N6O4 "C1CC(N(C1)C(=O)C2CCCN2C(=O)C(CCCNC(=N)N)N)C(=O)O

" Ambient -20°C "Mamenko M, Zaika O, Pochynyuk O. Direct regulation of ENaC by bradykinin in the distal nephron. Implications for renal sodium handling. Curr Opin Nephrol Hypertens. 2014 Mar;23(2):122-9. PMID: 24378775.

 

Yu HS, Wang SW, Chang AC, et al. Bradykinin promotes vascular endothelial growth factor expression and increases angiogenesis in human prostate cancer cells. Biochem Pharmacol. 2014 Jan 15;87(2):243-53. PMID: 24225154.

 

Dong R, Xu X, Li G, et al. Bradykinin inhibits oxidative stress-induced cardiomyocytes senescence via regulating redox state. PLoS One. 2013 Oct 25;8(10):e77034. PMID: 24204728.

 

Feher A, Cassuto J, Szabo A, et al. Increased tissue angiotensin-converting enzyme activity impairs bradykinin-induced dilation of coronary arterioles in obesity. Circ J. 2013;77(7):1867-76. PMID: 23603844.

" Not dangerous goods.

LKT B6802 Bradykinin (1-3) 10 mg 101.9 Natriuretic, vasodilatory peptide fragment; B1/2 agonist. 23815-91-0 ≥95% 368.4 C16H28N6O4 "C1CC(N(C1)C(=O)C2CCCN2C(=O)C(CCCNC(=N)N)N)C(=O)O

" Ambient -20°C "Mamenko M, Zaika O, Pochynyuk O. Direct regulation of ENaC by bradykinin in the distal nephron. Implications for renal sodium handling. Curr Opin Nephrol Hypertens. 2014 Mar;23(2):122-9. PMID: 24378775.

 

Yu HS, Wang SW, Chang AC, et al. Bradykinin promotes vascular endothelial growth factor expression and increases angiogenesis in human prostate cancer cells. Biochem Pharmacol. 2014 Jan 15;87(2):243-53. PMID: 24225154.

 

Dong R, Xu X, Li G, et al. Bradykinin inhibits oxidative stress-induced cardiomyocytes senescence via regulating redox state. PLoS One. 2013 Oct 25;8(10):e77034. PMID: 24204728.

 

Feher A, Cassuto J, Szabo A, et al. Increased tissue angiotensin-converting enzyme activity impairs bradykinin-induced dilation of coronary arterioles in obesity. Circ J. 2013;77(7):1867-76. PMID: 23603844.

" Not dangerous goods.

LKT B6802 Bradykinin (1-3) 25 mg 180 Natriuretic, vasodilatory peptide fragment; B1/2 agonist. 23815-91-0 ≥95% 368.4 C16H28N6O4 "C1CC(N(C1)C(=O)C2CCCN2C(=O)C(CCCNC(=N)N)N)C(=O)O

" Ambient -20°C "Mamenko M, Zaika O, Pochynyuk O. Direct regulation of ENaC by bradykinin in the distal nephron. Implications for renal sodium handling. Curr Opin Nephrol Hypertens. 2014 Mar;23(2):122-9. PMID: 24378775.

 

Yu HS, Wang SW, Chang AC, et al. Bradykinin promotes vascular endothelial growth factor expression and increases angiogenesis in human prostate cancer cells. Biochem Pharmacol. 2014 Jan 15;87(2):243-53. PMID: 24225154.

 

Dong R, Xu X, Li G, et al. Bradykinin inhibits oxidative stress-induced cardiomyocytes senescence via regulating redox state. PLoS One. 2013 Oct 25;8(10):e77034. PMID: 24204728.

 

Feher A, Cassuto J, Szabo A, et al. Increased tissue angiotensin-converting enzyme activity impairs bradykinin-induced dilation of coronary arterioles in obesity. Circ J. 2013;77(7):1867-76. PMID: 23603844.

" Not dangerous goods.

LKT B6803 Bradykinin (1-5) 5 mg 60 Natriuretic, vasodilatory peptide fragment; B1/2 agonist. 23815-89-6 ≥95% 572.67 C27H40N8O6 Ambient -20°C "Mamenko M, Zaika O, Pochynyuk O. Direct regulation of ENaC by bradykinin in the distal nephron. Implications for renal sodium handling. Curr Opin Nephrol Hypertens. 2014 Mar;23(2):122-9. PMID: 24378775.

 

Yu HS, Wang SW, Chang AC, et al. Bradykinin promotes vascular endothelial growth factor expression and increases angiogenesis in human prostate cancer cells. Biochem Pharmacol. 2014 Jan 15;87(2):243-53. PMID: 24225154.

 

Dong R, Xu X, Li G, et al. Bradykinin inhibits oxidative stress-induced cardiomyocytes senescence via regulating redox state. PLoS One. 2013 Oct 25;8(10):e77034. PMID: 24204728.

 

Feher A, Cassuto J, Szabo A, et al. Increased tissue angiotensin-converting enzyme activity impairs bradykinin-induced dilation of coronary arterioles in obesity. Circ J. 2013;77(7):1867-76. PMID: 23603844.

" Not dangerous goods.

LKT B6803 Bradykinin (1-5) 10 mg 101.9 Natriuretic, vasodilatory peptide fragment; B1/2 agonist. 23815-89-6 ≥95% 572.67 C27H40N8O6 Ambient -20°C "Mamenko M, Zaika O, Pochynyuk O. Direct regulation of ENaC by bradykinin in the distal nephron. Implications for renal sodium handling. Curr Opin Nephrol Hypertens. 2014 Mar;23(2):122-9. PMID: 24378775.

 

Yu HS, Wang SW, Chang AC, et al. Bradykinin promotes vascular endothelial growth factor expression and increases angiogenesis in human prostate cancer cells. Biochem Pharmacol. 2014 Jan 15;87(2):243-53. PMID: 24225154.

 

Dong R, Xu X, Li G, et al. Bradykinin inhibits oxidative stress-induced cardiomyocytes senescence via regulating redox state. PLoS One. 2013 Oct 25;8(10):e77034. PMID: 24204728.

 

Feher A, Cassuto J, Szabo A, et al. Increased tissue angiotensin-converting enzyme activity impairs bradykinin-induced dilation of coronary arterioles in obesity. Circ J. 2013;77(7):1867-76. PMID: 23603844.

" Not dangerous goods.

LKT B6803 Bradykinin (1-5) 25 mg 180 Natriuretic, vasodilatory peptide fragment; B1/2 agonist. 23815-89-6 ≥95% 572.67 C27H40N8O6 Ambient -20°C "Mamenko M, Zaika O, Pochynyuk O. Direct regulation of ENaC by bradykinin in the distal nephron. Implications for renal sodium handling. Curr Opin Nephrol Hypertens. 2014 Mar;23(2):122-9. PMID: 24378775.

 

Yu HS, Wang SW, Chang AC, et al. Bradykinin promotes vascular endothelial growth factor expression and increases angiogenesis in human prostate cancer cells. Biochem Pharmacol. 2014 Jan 15;87(2):243-53. PMID: 24225154.

 

Dong R, Xu X, Li G, et al. Bradykinin inhibits oxidative stress-induced cardiomyocytes senescence via regulating redox state. PLoS One. 2013 Oct 25;8(10):e77034. PMID: 24204728.

 

Feher A, Cassuto J, Szabo A, et al. Increased tissue angiotensin-converting enzyme activity impairs bradykinin-induced dilation of coronary arterioles in obesity. Circ J. 2013;77(7):1867-76. PMID: 23603844.

" Not dangerous goods.

LKT B6804 Bradykinin (1-6) 5 mg 60 Natriuretic, vasodilatory peptide fragment; B1/2 agonist. ≥95% 659.75 C30H45N9O8 Ambient -20°C "Mamenko M, Zaika O, Pochynyuk O. Direct regulation of ENaC by bradykinin in the distal nephron. Implications for renal sodium handling. Curr Opin Nephrol Hypertens. 2014 Mar;23(2):122-9. PMID: 24378775.

 

Yu HS, Wang SW, Chang AC, et al. Bradykinin promotes vascular endothelial growth factor expression and increases angiogenesis in human prostate cancer cells. Biochem Pharmacol. 2014 Jan 15;87(2):243-53. PMID: 24225154.

 

Dong R, Xu X, Li G, et al. Bradykinin inhibits oxidative stress-induced cardiomyocytes senescence via regulating redox state. PLoS One. 2013 Oct 25;8(10):e77034. PMID: 24204728.

 

Feher A, Cassuto J, Szabo A, et al. Increased tissue angiotensin-converting enzyme activity impairs bradykinin-induced dilation of coronary arterioles in obesity. Circ J. 2013;77(7):1867-76. PMID: 23603844.

" Not dangerous goods.

LKT B6804 Bradykinin (1-6) 10 mg 101.9 Natriuretic, vasodilatory peptide fragment; B1/2 agonist. ≥95% 659.75 C30H45N9O8 Ambient -20°C "Mamenko M, Zaika O, Pochynyuk O. Direct regulation of ENaC by bradykinin in the distal nephron. Implications for renal sodium handling. Curr Opin Nephrol Hypertens. 2014 Mar;23(2):122-9. PMID: 24378775.

 

Yu HS, Wang SW, Chang AC, et al. Bradykinin promotes vascular endothelial growth factor expression and increases angiogenesis in human prostate cancer cells. Biochem Pharmacol. 2014 Jan 15;87(2):243-53. PMID: 24225154.

 

Dong R, Xu X, Li G, et al. Bradykinin inhibits oxidative stress-induced cardiomyocytes senescence via regulating redox state. PLoS One. 2013 Oct 25;8(10):e77034. PMID: 24204728.

 

Feher A, Cassuto J, Szabo A, et al. Increased tissue angiotensin-converting enzyme activity impairs bradykinin-induced dilation of coronary arterioles in obesity. Circ J. 2013;77(7):1867-76. PMID: 23603844.

" Not dangerous goods.

LKT B6804 Bradykinin (1-6) 25 mg 180 Natriuretic, vasodilatory peptide fragment; B1/2 agonist. ≥95% 659.75 C30H45N9O8 Ambient -20°C "Mamenko M, Zaika O, Pochynyuk O. Direct regulation of ENaC by bradykinin in the distal nephron. Implications for renal sodium handling. Curr Opin Nephrol Hypertens. 2014 Mar;23(2):122-9. PMID: 24378775.

 

Yu HS, Wang SW, Chang AC, et al. Bradykinin promotes vascular endothelial growth factor expression and increases angiogenesis in human prostate cancer cells. Biochem Pharmacol. 2014 Jan 15;87(2):243-53. PMID: 24225154.

 

Dong R, Xu X, Li G, et al. Bradykinin inhibits oxidative stress-induced cardiomyocytes senescence via regulating redox state. PLoS One. 2013 Oct 25;8(10):e77034. PMID: 24204728.

 

Feher A, Cassuto J, Szabo A, et al. Increased tissue angiotensin-converting enzyme activity impairs bradykinin-induced dilation of coronary arterioles in obesity. Circ J. 2013;77(7):1867-76. PMID: 23603844.

" Not dangerous goods.

LKT B6805 Bradykinin (1-7) 5 mg 60 Natriuretic, vasodilatory peptide fragment; B1/2 agonist. ≥95% 756.87 C35H52N10O9 Ambient -20°C "Mamenko M, Zaika O, Pochynyuk O. Direct regulation of ENaC by bradykinin in the distal nephron. Implications for renal sodium handling. Curr Opin Nephrol Hypertens. 2014 Mar;23(2):122-9. PMID: 24378775.

 

Yu HS, Wang SW, Chang AC, et al. Bradykinin promotes vascular endothelial growth factor expression and increases angiogenesis in human prostate cancer cells. Biochem Pharmacol. 2014 Jan 15;87(2):243-53. PMID: 24225154.

 

Dong R, Xu X, Li G, et al. Bradykinin inhibits oxidative stress-induced cardiomyocytes senescence via regulating redox state. PLoS One. 2013 Oct 25;8(10):e77034. PMID: 24204728.

 

Feher A, Cassuto J, Szabo A, et al. Increased tissue angiotensin-converting enzyme activity impairs bradykinin-induced dilation of coronary arterioles in obesity. Circ J. 2013;77(7):1867-76. PMID: 23603844.

" Not dangerous goods.

LKT B6805 Bradykinin (1-7) 10 mg 101.9 Natriuretic, vasodilatory peptide fragment; B1/2 agonist. ≥95% 756.87 C35H52N10O9 Ambient -20°C "Mamenko M, Zaika O, Pochynyuk O. Direct regulation of ENaC by bradykinin in the distal nephron. Implications for renal sodium handling. Curr Opin Nephrol Hypertens. 2014 Mar;23(2):122-9. PMID: 24378775.

 

Yu HS, Wang SW, Chang AC, et al. Bradykinin promotes vascular endothelial growth factor expression and increases angiogenesis in human prostate cancer cells. Biochem Pharmacol. 2014 Jan 15;87(2):243-53. PMID: 24225154.

 

Dong R, Xu X, Li G, et al. Bradykinin inhibits oxidative stress-induced cardiomyocytes senescence via regulating redox state. PLoS One. 2013 Oct 25;8(10):e77034. PMID: 24204728.

 

Feher A, Cassuto J, Szabo A, et al. Increased tissue angiotensin-converting enzyme activity impairs bradykinin-induced dilation of coronary arterioles in obesity. Circ J. 2013;77(7):1867-76. PMID: 23603844.

" Not dangerous goods.

LKT B6805 Bradykinin (1-7) 25 mg 180 Natriuretic, vasodilatory peptide fragment; B1/2 agonist. ≥95% 756.87 C35H52N10O9 Ambient -20°C "Mamenko M, Zaika O, Pochynyuk O. Direct regulation of ENaC by bradykinin in the distal nephron. Implications for renal sodium handling. Curr Opin Nephrol Hypertens. 2014 Mar;23(2):122-9. PMID: 24378775.

 

Yu HS, Wang SW, Chang AC, et al. Bradykinin promotes vascular endothelial growth factor expression and increases angiogenesis in human prostate cancer cells. Biochem Pharmacol. 2014 Jan 15;87(2):243-53. PMID: 24225154.

 

Dong R, Xu X, Li G, et al. Bradykinin inhibits oxidative stress-induced cardiomyocytes senescence via regulating redox state. PLoS One. 2013 Oct 25;8(10):e77034. PMID: 24204728.

 

Feher A, Cassuto J, Szabo A, et al. Increased tissue angiotensin-converting enzyme activity impairs bradykinin-induced dilation of coronary arterioles in obesity. Circ J. 2013;77(7):1867-76. PMID: 23603844.

" Not dangerous goods.

LKT B6806 Bradykinin (2-9) 5 mg 60 Natriuretic, vasodilatory peptide fragment; B1/2 agonist. ≥95% 904.04 C44H61N11O10 Ambient -20°C "Mamenko M, Zaika O, Pochynyuk O. Direct regulation of ENaC by bradykinin in the distal nephron. Implications for renal sodium handling. Curr Opin Nephrol Hypertens. 2014 Mar;23(2):122-9. PMID: 24378775.

 

Yu HS, Wang SW, Chang AC, et al. Bradykinin promotes vascular endothelial growth factor expression and increases angiogenesis in human prostate cancer cells. Biochem Pharmacol. 2014 Jan 15;87(2):243-53. PMID: 24225154.

 

Dong R, Xu X, Li G, et al. Bradykinin inhibits oxidative stress-induced cardiomyocytes senescence via regulating redox state. PLoS One. 2013 Oct 25;8(10):e77034. PMID: 24204728.

 

Feher A, Cassuto J, Szabo A, et al. Increased tissue angiotensin-converting enzyme activity impairs bradykinin-induced dilation of coronary arterioles in obesity. Circ J. 2013;77(7):1867-76. PMID: 23603844.

" Not dangerous goods.

LKT B6806 Bradykinin (2-9) 10 mg 101.9 Natriuretic, vasodilatory peptide fragment; B1/2 agonist. ≥95% 904.04 C44H61N11O10 Ambient -20°C "Mamenko M, Zaika O, Pochynyuk O. Direct regulation of ENaC by bradykinin in the distal nephron. Implications for renal sodium handling. Curr Opin Nephrol Hypertens. 2014 Mar;23(2):122-9. PMID: 24378775.

 

Yu HS, Wang SW, Chang AC, et al. Bradykinin promotes vascular endothelial growth factor expression and increases angiogenesis in human prostate cancer cells. Biochem Pharmacol. 2014 Jan 15;87(2):243-53. PMID: 24225154.

 

Dong R, Xu X, Li G, et al. Bradykinin inhibits oxidative stress-induced cardiomyocytes senescence via regulating redox state. PLoS One. 2013 Oct 25;8(10):e77034. PMID: 24204728.

 

Feher A, Cassuto J, Szabo A, et al. Increased tissue angiotensin-converting enzyme activity impairs bradykinin-induced dilation of coronary arterioles in obesity. Circ J. 2013;77(7):1867-76. PMID: 23603844.

" Not dangerous goods.

LKT B6806 Bradykinin (2-9) 25 mg 180 Natriuretic, vasodilatory peptide fragment; B1/2 agonist. ≥95% 904.04 C44H61N11O10 Ambient -20°C "Mamenko M, Zaika O, Pochynyuk O. Direct regulation of ENaC by bradykinin in the distal nephron. Implications for renal sodium handling. Curr Opin Nephrol Hypertens. 2014 Mar;23(2):122-9. PMID: 24378775.

 

Yu HS, Wang SW, Chang AC, et al. Bradykinin promotes vascular endothelial growth factor expression and increases angiogenesis in human prostate cancer cells. Biochem Pharmacol. 2014 Jan 15;87(2):243-53. PMID: 24225154.

 

Dong R, Xu X, Li G, et al. Bradykinin inhibits oxidative stress-induced cardiomyocytes senescence via regulating redox state. PLoS One. 2013 Oct 25;8(10):e77034. PMID: 24204728.

 

Feher A, Cassuto J, Szabo A, et al. Increased tissue angiotensin-converting enzyme activity impairs bradykinin-induced dilation of coronary arterioles in obesity. Circ J. 2013;77(7):1867-76. PMID: 23603844.

" Not dangerous goods.

LKT B6807 [Des-Arg9]-Bradykinin 5 mg 72.1 Natriuretic, vasodilatory peptide, bradykinin analog; B1/2 agonist. ≥95% 904.04 C44H61N11O10 Ambient -20°C "Mamenko M, Zaika O, Pochynyuk O. Direct regulation of ENaC by bradykinin in the distal nephron. Implications for renal sodium handling. Curr Opin Nephrol Hypertens. 2014 Mar;23(2):122-9. PMID: 24378775.

 

Yu HS, Wang SW, Chang AC, et al. Bradykinin promotes vascular endothelial growth factor expression and increases angiogenesis in human prostate cancer cells. Biochem Pharmacol. 2014 Jan 15;87(2):243-53. PMID: 24225154.

 

Dong R, Xu X, Li G, et al. Bradykinin inhibits oxidative stress-induced cardiomyocytes senescence via regulating redox state. PLoS One. 2013 Oct 25;8(10):e77034. PMID: 24204728.

 

Feher A, Cassuto J, Szabo A, et al. Increased tissue angiotensin-converting enzyme activity impairs bradykinin-induced dilation of coronary arterioles in obesity. Circ J. 2013;77(7):1867-76. PMID: 23603844.

" Not dangerous goods.

LKT B6807 [Des-Arg9]-Bradykinin 10 mg 123.1 Natriuretic, vasodilatory peptide, bradykinin analog; B1/2 agonist. ≥95% 904.04 C44H61N11O10 Ambient -20°C "Mamenko M, Zaika O, Pochynyuk O. Direct regulation of ENaC by bradykinin in the distal nephron. Implications for renal sodium handling. Curr Opin Nephrol Hypertens. 2014 Mar;23(2):122-9. PMID: 24378775.

 

Yu HS, Wang SW, Chang AC, et al. Bradykinin promotes vascular endothelial growth factor expression and increases angiogenesis in human prostate cancer cells. Biochem Pharmacol. 2014 Jan 15;87(2):243-53. PMID: 24225154.

 

Dong R, Xu X, Li G, et al. Bradykinin inhibits oxidative stress-induced cardiomyocytes senescence via regulating redox state. PLoS One. 2013 Oct 25;8(10):e77034. PMID: 24204728.

 

Feher A, Cassuto J, Szabo A, et al. Increased tissue angiotensin-converting enzyme activity impairs bradykinin-induced dilation of coronary arterioles in obesity. Circ J. 2013;77(7):1867-76. PMID: 23603844.

" Not dangerous goods.

LKT B6807 [Des-Arg9]-Bradykinin 25 mg 216.1 Natriuretic, vasodilatory peptide, bradykinin analog; B1/2 agonist. ≥95% 904.04 C44H61N11O10 Ambient -20°C "Mamenko M, Zaika O, Pochynyuk O. Direct regulation of ENaC by bradykinin in the distal nephron. Implications for renal sodium handling. Curr Opin Nephrol Hypertens. 2014 Mar;23(2):122-9. PMID: 24378775.

 

Yu HS, Wang SW, Chang AC, et al. Bradykinin promotes vascular endothelial growth factor expression and increases angiogenesis in human prostate cancer cells. Biochem Pharmacol. 2014 Jan 15;87(2):243-53. PMID: 24225154.

 

Dong R, Xu X, Li G, et al. Bradykinin inhibits oxidative stress-induced cardiomyocytes senescence via regulating redox state. PLoS One. 2013 Oct 25;8(10):e77034. PMID: 24204728.

 

Feher A, Cassuto J, Szabo A, et al. Increased tissue angiotensin-converting enzyme activity impairs bradykinin-induced dilation of coronary arterioles in obesity. Circ J. 2013;77(7):1867-76. PMID: 23603844.

" Not dangerous goods.

LKT B6808 [Des-Pro2]-Bradykinin 5 mg 72.1 Natriuretic, vasodilatory peptide, bradykinin analog; B1/2 agonist. ≥95% 963.12 C45H66N14O10 Ambient -20°C "Mamenko M, Zaika O, Pochynyuk O. Direct regulation of ENaC by bradykinin in the distal nephron. Implications for renal sodium handling. Curr Opin Nephrol Hypertens. 2014 Mar;23(2):122-9. PMID: 24378775.

 

Yu HS, Wang SW, Chang AC, et al. Bradykinin promotes vascular endothelial growth factor expression and increases angiogenesis in human prostate cancer cells. Biochem Pharmacol. 2014 Jan 15;87(2):243-53. PMID: 24225154.

 

Dong R, Xu X, Li G, et al. Bradykinin inhibits oxidative stress-induced cardiomyocytes senescence via regulating redox state. PLoS One. 2013 Oct 25;8(10):e77034. PMID: 24204728.

 

Feher A, Cassuto J, Szabo A, et al. Increased tissue angiotensin-converting enzyme activity impairs bradykinin-induced dilation of coronary arterioles in obesity. Circ J. 2013;77(7):1867-76. PMID: 23603844.

" Not dangerous goods.

LKT B6808 [Des-Pro2]-Bradykinin 10 mg 123.1 Natriuretic, vasodilatory peptide, bradykinin analog; B1/2 agonist. ≥95% 963.12 C45H66N14O10 Ambient -20°C "Mamenko M, Zaika O, Pochynyuk O. Direct regulation of ENaC by bradykinin in the distal nephron. Implications for renal sodium handling. Curr Opin Nephrol Hypertens. 2014 Mar;23(2):122-9. PMID: 24378775.

 

Yu HS, Wang SW, Chang AC, et al. Bradykinin promotes vascular endothelial growth factor expression and increases angiogenesis in human prostate cancer cells. Biochem Pharmacol. 2014 Jan 15;87(2):243-53. PMID: 24225154.

 

Dong R, Xu X, Li G, et al. Bradykinin inhibits oxidative stress-induced cardiomyocytes senescence via regulating redox state. PLoS One. 2013 Oct 25;8(10):e77034. PMID: 24204728.

 

Feher A, Cassuto J, Szabo A, et al. Increased tissue angiotensin-converting enzyme activity impairs bradykinin-induced dilation of coronary arterioles in obesity. Circ J. 2013;77(7):1867-76. PMID: 23603844.

" Not dangerous goods.

LKT B6808 [Des-Pro2]-Bradykinin 25 mg 216.1 Natriuretic, vasodilatory peptide, bradykinin analog; B1/2 agonist. ≥95% 963.12 C45H66N14O10 Ambient -20°C "Mamenko M, Zaika O, Pochynyuk O. Direct regulation of ENaC by bradykinin in the distal nephron. Implications for renal sodium handling. Curr Opin Nephrol Hypertens. 2014 Mar;23(2):122-9. PMID: 24378775.

 

Yu HS, Wang SW, Chang AC, et al. Bradykinin promotes vascular endothelial growth factor expression and increases angiogenesis in human prostate cancer cells. Biochem Pharmacol. 2014 Jan 15;87(2):243-53. PMID: 24225154.

 

Dong R, Xu X, Li G, et al. Bradykinin inhibits oxidative stress-induced cardiomyocytes senescence via regulating redox state. PLoS One. 2013 Oct 25;8(10):e77034. PMID: 24204728.

 

Feher A, Cassuto J, Szabo A, et al. Increased tissue angiotensin-converting enzyme activity impairs bradykinin-induced dilation of coronary arterioles in obesity. Circ J. 2013;77(7):1867-76. PMID: 23603844.

" Not dangerous goods.

LKT B6809 [DPhe7]-Bradykinin 1 mg 48 Natriuretic, vasodilatory peptide, bradykinin analog; B1/2 agonist. ≥95% 1110.29 C54H75N15O11 Ambient -20°C "Mamenko M, Zaika O, Pochynyuk O. Direct regulation of ENaC by bradykinin in the distal nephron. Implications for renal sodium handling. Curr Opin Nephrol Hypertens. 2014 Mar;23(2):122-9. PMID: 24378775.

 

Yu HS, Wang SW, Chang AC, et al. Bradykinin promotes vascular endothelial growth factor expression and increases angiogenesis in human prostate cancer cells. Biochem Pharmacol. 2014 Jan 15;87(2):243-53. PMID: 24225154.

 

Dong R, Xu X, Li G, et al. Bradykinin inhibits oxidative stress-induced cardiomyocytes senescence via regulating redox state. PLoS One. 2013 Oct 25;8(10):e77034. PMID: 24204728.

 

Feher A, Cassuto J, Szabo A, et al. Increased tissue angiotensin-converting enzyme activity impairs bradykinin-induced dilation of coronary arterioles in obesity. Circ J. 2013;77(7):1867-76. PMID: 23603844.

" Not dangerous goods.

LKT B6809 [DPhe7]-Bradykinin 2 mg 81 Natriuretic, vasodilatory peptide, bradykinin analog; B1/2 agonist. ≥95% 1110.29 C54H75N15O11 Ambient -20°C "Mamenko M, Zaika O, Pochynyuk O. Direct regulation of ENaC by bradykinin in the distal nephron. Implications for renal sodium handling. Curr Opin Nephrol Hypertens. 2014 Mar;23(2):122-9. PMID: 24378775.

 

Yu HS, Wang SW, Chang AC, et al. Bradykinin promotes vascular endothelial growth factor expression and increases angiogenesis in human prostate cancer cells. Biochem Pharmacol. 2014 Jan 15;87(2):243-53. PMID: 24225154.

 

Dong R, Xu X, Li G, et al. Bradykinin inhibits oxidative stress-induced cardiomyocytes senescence via regulating redox state. PLoS One. 2013 Oct 25;8(10):e77034. PMID: 24204728.

 

Feher A, Cassuto J, Szabo A, et al. Increased tissue angiotensin-converting enzyme activity impairs bradykinin-induced dilation of coronary arterioles in obesity. Circ J. 2013;77(7):1867-76. PMID: 23603844.

" Not dangerous goods.

LKT B6809 [DPhe7]-Bradykinin 5 mg 144 Natriuretic, vasodilatory peptide, bradykinin analog; B1/2 agonist. ≥95% 1110.29 C54H75N15O11 Ambient -20°C "Mamenko M, Zaika O, Pochynyuk O. Direct regulation of ENaC by bradykinin in the distal nephron. Implications for renal sodium handling. Curr Opin Nephrol Hypertens. 2014 Mar;23(2):122-9. PMID: 24378775.

 

Yu HS, Wang SW, Chang AC, et al. Bradykinin promotes vascular endothelial growth factor expression and increases angiogenesis in human prostate cancer cells. Biochem Pharmacol. 2014 Jan 15;87(2):243-53. PMID: 24225154.

 

Dong R, Xu X, Li G, et al. Bradykinin inhibits oxidative stress-induced cardiomyocytes senescence via regulating redox state. PLoS One. 2013 Oct 25;8(10):e77034. PMID: 24204728.

 

Feher A, Cassuto J, Szabo A, et al. Increased tissue angiotensin-converting enzyme activity impairs bradykinin-induced dilation of coronary arterioles in obesity. Circ J. 2013;77(7):1867-76. PMID: 23603844.

" Not dangerous goods.

LKT B6810 [Hyp3]-Bradykinin 2.5 mg 216.1 Natriuretic, vasodilatory peptide, bradykinin analog; B1/2 agonist. ≥95% 1077.23 C30H72N15O10 Ambient -20°C "Mamenko M, Zaika O, Pochynyuk O. Direct regulation of ENaC by bradykinin in the distal nephron. Implications for renal sodium handling. Curr Opin Nephrol Hypertens. 2014 Mar;23(2):122-9. PMID: 24378775.

 

Yu HS, Wang SW, Chang AC, et al. Bradykinin promotes vascular endothelial growth factor expression and increases angiogenesis in human prostate cancer cells. Biochem Pharmacol. 2014 Jan 15;87(2):243-53. PMID: 24225154.

 

Dong R, Xu X, Li G, et al. Bradykinin inhibits oxidative stress-induced cardiomyocytes senescence via regulating redox state. PLoS One. 2013 Oct 25;8(10):e77034. PMID: 24204728.

 

Feher A, Cassuto J, Szabo A, et al. Increased tissue angiotensin-converting enzyme activity impairs bradykinin-induced dilation of coronary arterioles in obesity. Circ J. 2013;77(7):1867-76. PMID: 23603844.

" Not dangerous goods.

LKT B6810 [Hyp3]-Bradykinin 1 mg 123.1 Natriuretic, vasodilatory peptide, bradykinin analog; B1/2 agonist. ≥95% 1077.23 C30H72N15O10 Ambient -20°C "Mamenko M, Zaika O, Pochynyuk O. Direct regulation of ENaC by bradykinin in the distal nephron. Implications for renal sodium handling. Curr Opin Nephrol Hypertens. 2014 Mar;23(2):122-9. PMID: 24378775.

 

Yu HS, Wang SW, Chang AC, et al. Bradykinin promotes vascular endothelial growth factor expression and increases angiogenesis in human prostate cancer cells. Biochem Pharmacol. 2014 Jan 15;87(2):243-53. PMID: 24225154.

 

Dong R, Xu X, Li G, et al. Bradykinin inhibits oxidative stress-induced cardiomyocytes senescence via regulating redox state. PLoS One. 2013 Oct 25;8(10):e77034. PMID: 24204728.

 

Feher A, Cassuto J, Szabo A, et al. Increased tissue angiotensin-converting enzyme activity impairs bradykinin-induced dilation of coronary arterioles in obesity. Circ J. 2013;77(7):1867-76. PMID: 23603844.

" Not dangerous goods.

LKT B6810 [Hyp3]-Bradykinin 0.5 mg 72.1 Natriuretic, vasodilatory peptide, bradykinin analog; B1/2 agonist. ≥95% 1077.23 C30H72N15O10 Ambient -20°C "Mamenko M, Zaika O, Pochynyuk O. Direct regulation of ENaC by bradykinin in the distal nephron. Implications for renal sodium handling. Curr Opin Nephrol Hypertens. 2014 Mar;23(2):122-9. PMID: 24378775.

 

Yu HS, Wang SW, Chang AC, et al. Bradykinin promotes vascular endothelial growth factor expression and increases angiogenesis in human prostate cancer cells. Biochem Pharmacol. 2014 Jan 15;87(2):243-53. PMID: 24225154.

 

Dong R, Xu X, Li G, et al. Bradykinin inhibits oxidative stress-induced cardiomyocytes senescence via regulating redox state. PLoS One. 2013 Oct 25;8(10):e77034. PMID: 24204728.

 

Feher A, Cassuto J, Szabo A, et al. Increased tissue angiotensin-converting enzyme activity impairs bradykinin-induced dilation of coronary arterioles in obesity. Circ J. 2013;77(7):1867-76. PMID: 23603844.

" Not dangerous goods.

LKT B6811 [Tyr8]-Bradykinin 5 mg 83.9 Natriuretic, vasodilatory peptide, bradykinin analog; B1/2 agonist. ≥95% 1076.23 C50H73N15O12 Ambient -20°C "Mamenko M, Zaika O, Pochynyuk O. Direct regulation of ENaC by bradykinin in the distal nephron. Implications for renal sodium handling. Curr Opin Nephrol Hypertens. 2014 Mar;23(2):122-9. PMID: 24378775.

 

Yu HS, Wang SW, Chang AC, et al. Bradykinin promotes vascular endothelial growth factor expression and increases angiogenesis in human prostate cancer cells. Biochem Pharmacol. 2014 Jan 15;87(2):243-53. PMID: 24225154.

 

Dong R, Xu X, Li G, et al. Bradykinin inhibits oxidative stress-induced cardiomyocytes senescence via regulating redox state. PLoS One. 2013 Oct 25;8(10):e77034. PMID: 24204728.

 

Feher A, Cassuto J, Szabo A, et al. Increased tissue angiotensin-converting enzyme activity impairs bradykinin-induced dilation of coronary arterioles in obesity. Circ J. 2013;77(7):1867-76. PMID: 23603844.

" Not dangerous goods.

LKT B6811 [Tyr8]-Bradykinin 10 mg 144 Natriuretic, vasodilatory peptide, bradykinin analog; B1/2 agonist. ≥95% 1076.23 C50H73N15O12 Ambient -20°C "Mamenko M, Zaika O, Pochynyuk O. Direct regulation of ENaC by bradykinin in the distal nephron. Implications for renal sodium handling. Curr Opin Nephrol Hypertens. 2014 Mar;23(2):122-9. PMID: 24378775.

 

Yu HS, Wang SW, Chang AC, et al. Bradykinin promotes vascular endothelial growth factor expression and increases angiogenesis in human prostate cancer cells. Biochem Pharmacol. 2014 Jan 15;87(2):243-53. PMID: 24225154.

 

Dong R, Xu X, Li G, et al. Bradykinin inhibits oxidative stress-induced cardiomyocytes senescence via regulating redox state. PLoS One. 2013 Oct 25;8(10):e77034. PMID: 24204728.

 

Feher A, Cassuto J, Szabo A, et al. Increased tissue angiotensin-converting enzyme activity impairs bradykinin-induced dilation of coronary arterioles in obesity. Circ J. 2013;77(7):1867-76. PMID: 23603844.

" Not dangerous goods.

LKT B6811 [Tyr8]-Bradykinin 50 mg 252.1 Natriuretic, vasodilatory peptide, bradykinin analog; B1/2 agonist. ≥95% 1076.23 C50H73N15O12 Ambient -20°C "Mamenko M, Zaika O, Pochynyuk O. Direct regulation of ENaC by bradykinin in the distal nephron. Implications for renal sodium handling. Curr Opin Nephrol Hypertens. 2014 Mar;23(2):122-9. PMID: 24378775.

 

Yu HS, Wang SW, Chang AC, et al. Bradykinin promotes vascular endothelial growth factor expression and increases angiogenesis in human prostate cancer cells. Biochem Pharmacol. 2014 Jan 15;87(2):243-53. PMID: 24225154.

 

Dong R, Xu X, Li G, et al. Bradykinin inhibits oxidative stress-induced cardiomyocytes senescence via regulating redox state. PLoS One. 2013 Oct 25;8(10):e77034. PMID: 24204728.

 

Feher A, Cassuto J, Szabo A, et al. Increased tissue angiotensin-converting enzyme activity impairs bradykinin-induced dilation of coronary arterioles in obesity. Circ J. 2013;77(7):1867-76. PMID: 23603844.

" Not dangerous goods.

LKT B6812 Bradykinin Potentiator B 5 mg 72.1 Peptide found in Agkistrodon vipers; bradykinin inhibiting peptidase and ACE inhibitor. ≥95% 1182.46 C56H91N15O13 Ambient -20°C "Matsui H, Takahashi T. Presence of angiotensin-converting enzyme in follicular fluids of porcine ovaries and its possible involvement in the intrafollicular breakdown of bradykinin. Mol Reprod Dev. 2002 May;62(1):99-105. PMID: 11933166.

 

Kariya K, Okamoto H, Kira K. Kinin-forming enzyme in rat brain mitochondria fraction and biological activity of a kinin released from rat plasma kininogen by this enzyme. Jpn J Pharmacol. 1984 Feb;34(2):203-10. PMID: 6748370.

 

Kato H, Suzuki T. Bradykinin-potentiating peptides from the venom of Agkistrodon halys blomhoffi. Isolation of five bradykinin potentiators and the amino acid sequences of two of them, potentiators B and C. Biochemistry. 1971 Mar 16;10(6):972-80.  PMID: 4323853.

" Not dangerous goods.

LKT B6812 Bradykinin Potentiator B 10 mg 123.1 Peptide found in Agkistrodon vipers; bradykinin inhibiting peptidase and ACE inhibitor. ≥95% 1182.46 C56H91N15O13 Ambient -20°C "Matsui H, Takahashi T. Presence of angiotensin-converting enzyme in follicular fluids of porcine ovaries and its possible involvement in the intrafollicular breakdown of bradykinin. Mol Reprod Dev. 2002 May;62(1):99-105. PMID: 11933166.

 

Kariya K, Okamoto H, Kira K. Kinin-forming enzyme in rat brain mitochondria fraction and biological activity of a kinin released from rat plasma kininogen by this enzyme. Jpn J Pharmacol. 1984 Feb;34(2):203-10. PMID: 6748370.

 

Kato H, Suzuki T. Bradykinin-potentiating peptides from the venom of Agkistrodon halys blomhoffi. Isolation of five bradykinin potentiators and the amino acid sequences of two of them, potentiators B and C. Biochemistry. 1971 Mar 16;10(6):972-80.  PMID: 4323853.

" Not dangerous goods.

LKT B6812 Bradykinin Potentiator B 25 mg 216.1 Peptide found in Agkistrodon vipers; bradykinin inhibiting peptidase and ACE inhibitor. ≥95% 1182.46 C56H91N15O13 Ambient -20°C "Matsui H, Takahashi T. Presence of angiotensin-converting enzyme in follicular fluids of porcine ovaries and its possible involvement in the intrafollicular breakdown of bradykinin. Mol Reprod Dev. 2002 May;62(1):99-105. PMID: 11933166.

 

Kariya K, Okamoto H, Kira K. Kinin-forming enzyme in rat brain mitochondria fraction and biological activity of a kinin released from rat plasma kininogen by this enzyme. Jpn J Pharmacol. 1984 Feb;34(2):203-10. PMID: 6748370.

 

Kato H, Suzuki T. Bradykinin-potentiating peptides from the venom of Agkistrodon halys blomhoffi. Isolation of five bradykinin potentiators and the amino acid sequences of two of them, potentiators B and C. Biochemistry. 1971 Mar 16;10(6):972-80.  PMID: 4323853.

" Not dangerous goods.

LKT B6813 Bradykinin Potentiator C 5 mg 72.1 Peptide found in Agkistrodon vipers; bradykinin inhibiting peptidase and ACE inhibitor. ≥95% 1052.26 C51H77N11O13 Ambient -20°C "Matsui H, Takahashi T. Presence of angiotensin-converting enzyme in follicular fluids of porcine ovaries and its possible involvement in the intrafollicular breakdown of bradykinin. Mol Reprod Dev. 2002 May;62(1):99-105. PMID: 11933166.

 

Kariya K, Okamoto H, Kira K. Kinin-forming enzyme in rat brain mitochondria fraction and biological activity of a kinin released from rat plasma kininogen by this enzyme. Jpn J Pharmacol. 1984 Feb;34(2):203-10. PMID: 6748370.

 

Kato H, Suzuki T. Bradykinin-potentiating peptides from the venom of Agkistrodon halys blomhoffi. Isolation of five bradykinin potentiators and the amino acid sequences of two of them, potentiators B and C. Biochemistry. 1971 Mar 16;10(6):972-80.  PMID: 4323853.

" Not dangerous goods.

LKT B6813 Bradykinin Potentiator C 10 mg 123.1 Peptide found in Agkistrodon vipers; bradykinin inhibiting peptidase and ACE inhibitor. ≥95% 1052.26 C51H77N11O13 Ambient -20°C "Matsui H, Takahashi T. Presence of angiotensin-converting enzyme in follicular fluids of porcine ovaries and its possible involvement in the intrafollicular breakdown of bradykinin. Mol Reprod Dev. 2002 May;62(1):99-105. PMID: 11933166.

 

Kariya K, Okamoto H, Kira K. Kinin-forming enzyme in rat brain mitochondria fraction and biological activity of a kinin released from rat plasma kininogen by this enzyme. Jpn J Pharmacol. 1984 Feb;34(2):203-10. PMID: 6748370.

 

Kato H, Suzuki T. Bradykinin-potentiating peptides from the venom of Agkistrodon halys blomhoffi. Isolation of five bradykinin potentiators and the amino acid sequences of two of them, potentiators B and C. Biochemistry. 1971 Mar 16;10(6):972-80.  PMID: 4323853.

" Not dangerous goods.

LKT B6813 Bradykinin Potentiator C 25 mg 216.1 Peptide found in Agkistrodon vipers; bradykinin inhibiting peptidase and ACE inhibitor. ≥95% 1052.26 C51H77N11O13 Ambient -20°C "Matsui H, Takahashi T. Presence of angiotensin-converting enzyme in follicular fluids of porcine ovaries and its possible involvement in the intrafollicular breakdown of bradykinin. Mol Reprod Dev. 2002 May;62(1):99-105. PMID: 11933166.

 

Kariya K, Okamoto H, Kira K. Kinin-forming enzyme in rat brain mitochondria fraction and biological activity of a kinin released from rat plasma kininogen by this enzyme. Jpn J Pharmacol. 1984 Feb;34(2):203-10. PMID: 6748370.

 

Kato H, Suzuki T. Bradykinin-potentiating peptides from the venom of Agkistrodon halys blomhoffi. Isolation of five bradykinin potentiators and the amino acid sequences of two of them, potentiators B and C. Biochemistry. 1971 Mar 16;10(6):972-80.  PMID: 4323853.

" Not dangerous goods.

LKT B6816 Brefeldin A 5 mg 61.1 Lactone found in fungi such as Eupenicillium; guanine nucleotide exchange factor inhibitor. 1,6,7,8,9,11a,12,13,14,14a-Decahydro-1,13-dihydroxy- 6-methyl-4H-cyclopent[f]oxacyclotridecin-4-one Ascotoxin; Cyanein; Decumbin 20350-15-6 ≥97% 280.36 C16H24O4 CC1CCCC=CC2CC(CC2C(C=CC(=O)O1)O)O Ambient -20°C Soluble in methanol. "Zhou C, Li C, Li D, et al. BIG1, a brefeldin A-inhibited guanine nucleotide-exchange protein regulates neurite development via PI3K-AKT and ERK signaling pathways. Neuroscience. 2013 Dec 19;254:361-8. PMID: 24090963.

 

Rouhana J, Padilla A, Estaran S, et al. Kinetics of interaction between ADP-ribosylation factor-1 (Arf1) and the Sec7 domain of Arno guanine nucleotide exchange factor, modulation by allosteric factors, and the uncompetitive inhibitor brefeldin A. J Biol Chem. 2013 Feb 15;288(7):4659-72. PMID: 23255605.

 

Chapman JR, Tazaki H, Mallouh C, et al. Brefeldin A-induced apoptosis in prostatic cancer DU-145 cells: a possible p53-independent death pathway. BJU Int. 1999 Apr;83(6):703-8. PMID: 10233583.

 

Cuconati A, Molla A, Wimmer E. Brefeldin A inhibits cell-free, de novo synthesis of poliovirus. J Virol. 1998 Aug;72(8):6456-64. PMID: 9658088.

" T "UN number: 2811     Class:  6.1     Packing group:  III

Proper shipping name:  Toxic solids, organic, n.o.s. (Brefeldin A)

Reportable quantity (RQ):     Marine pollutant:  no     Poison inhalation hazard:  No"

LKT B6816 Brefeldin A 10 mg 101.9 Lactone found in fungi such as Eupenicillium; guanine nucleotide exchange factor inhibitor. 1,6,7,8,9,11a,12,13,14,14a-Decahydro-1,13-dihydroxy- 6-methyl-4H-cyclopent[f]oxacyclotridecin-4-one Ascotoxin; Cyanein; Decumbin 20350-15-6 ≥97% 280.36 C16H24O4 CC1CCCC=CC2CC(CC2C(C=CC(=O)O1)O)O Ambient -20°C Soluble in methanol. "Zhou C, Li C, Li D, et al. BIG1, a brefeldin A-inhibited guanine nucleotide-exchange protein regulates neurite development via PI3K-AKT and ERK signaling pathways. Neuroscience. 2013 Dec 19;254:361-8. PMID: 24090963.

 

Rouhana J, Padilla A, Estaran S, et al. Kinetics of interaction between ADP-ribosylation factor-1 (Arf1) and the Sec7 domain of Arno guanine nucleotide exchange factor, modulation by allosteric factors, and the uncompetitive inhibitor brefeldin A. J Biol Chem. 2013 Feb 15;288(7):4659-72. PMID: 23255605.

 

Chapman JR, Tazaki H, Mallouh C, et al. Brefeldin A-induced apoptosis in prostatic cancer DU-145 cells: a possible p53-independent death pathway. BJU Int. 1999 Apr;83(6):703-8. PMID: 10233583.

 

Cuconati A, Molla A, Wimmer E. Brefeldin A inhibits cell-free, de novo synthesis of poliovirus. J Virol. 1998 Aug;72(8):6456-64. PMID: 9658088.

" T "UN number: 2811     Class:  6.1     Packing group:  III

Proper shipping name:  Toxic solids, organic, n.o.s. (Brefeldin A)

Reportable quantity (RQ):     Marine pollutant:  no     Poison inhalation hazard:  No"

LKT T6811 Tranexamic Acid 5 g 31.6 Plasminogen inhibitor. "Cyclohexanecarboxylic acid, 4-(aminomethyl)-, trans- 

" Tranexan; Tranex; Transamin; Hexatron; Spiramin; Rikavarin; Ugurol; Trasamlon. 1197-18-8 ≥98% 157.21 C8H15NO2 C1CC(CCC1CN)C(=O)O Stable at room temperature. Ambient Ambient Soluble in water(125mg/mL). Very slightly soluble in alcohol, DMSO or ether. "Yuan C, Wang XM, Yang LJ, et al. Tranexamic acid accelerates skin barrier recovery and upregulates occludin in damaged skin. Int J Dermatol. 2013 Aug 22. [Epub ahead of print]. PMID: 23967870.

 

Sperzel M, Huetter J. Evaluation of aprotinin and tranexamic acid in different in vitro and in vivo models of fibrinolysis, coagulation and thrombus formation. J Thromb Haemost. 2007 Oct;5(10):2113-8. PMID: 17666018.

" Xi Not dangerous goods.

LKT T6811 Tranexamic Acid 10 g 52.6 Plasminogen inhibitor. "Cyclohexanecarboxylic acid, 4-(aminomethyl)-, trans- 

" Tranexan; Tranex; Transamin; Hexatron; Spiramin; Rikavarin; Ugurol; Trasamlon. 1197-18-8 ≥98% 157.21 C8H15NO2 C1CC(CCC1CN)C(=O)O Stable at room temperature. Ambient Ambient Soluble in water(125mg/mL). Very slightly soluble in alcohol, DMSO or ether. "Yuan C, Wang XM, Yang LJ, et al. Tranexamic acid accelerates skin barrier recovery and upregulates occludin in damaged skin. Int J Dermatol. 2013 Aug 22. [Epub ahead of print]. PMID: 23967870.

 

Sperzel M, Huetter J. Evaluation of aprotinin and tranexamic acid in different in vitro and in vivo models of fibrinolysis, coagulation and thrombus formation. J Thromb Haemost. 2007 Oct;5(10):2113-8. PMID: 17666018.

" Xi Not dangerous goods.

LKT T6811 Tranexamic Acid 50 g 168 Plasminogen inhibitor. "Cyclohexanecarboxylic acid, 4-(aminomethyl)-, trans- 

" Tranexan; Tranex; Transamin; Hexatron; Spiramin; Rikavarin; Ugurol; Trasamlon. 1197-18-8 ≥98% 157.21 C8H15NO2 C1CC(CCC1CN)C(=O)O Stable at room temperature. Ambient Ambient Soluble in water(125mg/mL). Very slightly soluble in alcohol, DMSO or ether. "Yuan C, Wang XM, Yang LJ, et al. Tranexamic acid accelerates skin barrier recovery and upregulates occludin in damaged skin. Int J Dermatol. 2013 Aug 22. [Epub ahead of print]. PMID: 23967870.

 

Sperzel M, Huetter J. Evaluation of aprotinin and tranexamic acid in different in vitro and in vivo models of fibrinolysis, coagulation and thrombus formation. J Thromb Haemost. 2007 Oct;5(10):2113-8. PMID: 17666018.

" Xi Not dangerous goods.

LKT B6857 4-Bromoflavone 1 g 40.7 Nrf2-Keap1-ARE complex activator. 6-Bromo-2-phenylbenzopyran; 6-Bromo-2-pheynyl- 4H-1-benzopyran-4-one; 6-Bromoflavone 1218-80-0 ≥98% 301.13 C15H9BrO2 C1=CC=C(C=C1)C2=CC(=O)C3=C(O2)C=CC(=C3)Br Ambient Ambient "Lee JS, Surh YJ. Nrf2 as a novel molecular target for chemoprevention. Cancer Lett. 2005 Jun 28;224(2):171-84. PMID: 15914268.

 

Mehta RG, Pezzuto JM. Discovery of cancer preventive agents from natural products: from plants to prevention. Curr Oncol Rep. 2002 Nov;4(6):478-86. PMID: 12354359.

 

Song LL, Kosmeder JW 2nd, Lee SK, et al. Cancer chemopreventive activity mediated by 4'-bromoflavone, a potent inducer of phase II detoxification enzymes. Cancer Res. 1999 Feb 1;59(3):578-85. PMID: 9973203.

" Xi Not dangerous goods.

LKT B6857 4-Bromoflavone 5 g 149.5 Nrf2-Keap1-ARE complex activator. 6-Bromo-2-phenylbenzopyran; 6-Bromo-2-pheynyl- 4H-1-benzopyran-4-one; 6-Bromoflavone 1218-80-0 ≥98% 301.13 C15H9BrO2 C1=CC=C(C=C1)C2=CC(=O)C3=C(O2)C=CC(=C3)Br Ambient Ambient "Lee JS, Surh YJ. Nrf2 as a novel molecular target for chemoprevention. Cancer Lett. 2005 Jun 28;224(2):171-84. PMID: 15914268.

 

Mehta RG, Pezzuto JM. Discovery of cancer preventive agents from natural products: from plants to prevention. Curr Oncol Rep. 2002 Nov;4(6):478-86. PMID: 12354359.

 

Song LL, Kosmeder JW 2nd, Lee SK, et al. Cancer chemopreventive activity mediated by 4'-bromoflavone, a potent inducer of phase II detoxification enzymes. Cancer Res. 1999 Feb 1;59(3):578-85. PMID: 9973203.

" Xi Not dangerous goods.

LKT B6857 4-Bromoflavone 10 g 251.5 Nrf2-Keap1-ARE complex activator. 6-Bromo-2-phenylbenzopyran; 6-Bromo-2-pheynyl- 4H-1-benzopyran-4-one; 6-Bromoflavone 1218-80-0 ≥98% 301.13 C15H9BrO2 C1=CC=C(C=C1)C2=CC(=O)C3=C(O2)C=CC(=C3)Br Ambient Ambient "Lee JS, Surh YJ. Nrf2 as a novel molecular target for chemoprevention. Cancer Lett. 2005 Jun 28;224(2):171-84. PMID: 15914268.

 

Mehta RG, Pezzuto JM. Discovery of cancer preventive agents from natural products: from plants to prevention. Curr Oncol Rep. 2002 Nov;4(6):478-86. PMID: 12354359.

 

Song LL, Kosmeder JW 2nd, Lee SK, et al. Cancer chemopreventive activity mediated by 4'-bromoflavone, a potent inducer of phase II detoxification enzymes. Cancer Res. 1999 Feb 1;59(3):578-85. PMID: 9973203.

" Xi Not dangerous goods.

LKT B6935 Brivudine 10 mg 234.5 Nucleoside (thymidine) analog; DNA chain terminator, HSV-1 thymidine kinase inhibitor, HSP27 modulator. 5-[(E)-2-bromoethenyl]-1-[(2R,4S,5R)-4-hydroxy-5-(hydroxymethyl)oxolan-2-yl]-1,2,3,4-tetrahydropyrimidine-2,4-dione 69304-47-8 ≥98% 333.13 C11H13BrN2O5 C1C(C(OC1N2C=C(C(=O)NC2=O)C=CBr)CO)O Ambient Ambient "Heinrich JC, Tuukkanen A, Schroeder M, et al. RP101 (brivudine) binds to heat shock protein HSP27 (HSPB1) and enhances survival in animals and pancreatic cancer patients. J Cancer Res Clin Oncol. 2011 Sep;137(9):1349-61. PMID: 21833720.

 

Breuer M, De Loof A, Balzarini J, et al. Insecticidal activity of the pyrimidine nucleoside analogue (E)-5-(2-bromovinyl)-2'-deoxyuridine (BVDU). Pest Manag Sci. 2005 Aug;61(8):737-41. PMID: 15838935.

 

Spadari S, Ciarrocchi G, Focher F, et al. 5-Iodo-2'-deoxy-L-uridine and (E)-5-(2-bromovinyl)-2'-deoxy-L-uridine: selective phosphorylation by herpes simplex virus type 1 thymidine kinase, antiherpetic activity, and cytotoxicity studies. Mol Pharmacol. 1995 Jun;47(6):1231-8. PMID: 7603465.

 

Balzarini J, Bohman C, De Clercq E. Differential mechanism of cytostatic effect of (E)-5-(2-bromovinyl)-2'-deoxyuridine, 9-(1,3-dihydroxy-2-propoxymethyl)guanine, and other antiherpetic drugs on tumor cells transfected by the thymidine kinase gene of herpes simplex virus type 1 or type 2. J Biol Chem. 1993 Mar 25;268(9):6332-7. PMID: 8384209.

" Not dangerous goods.

LKT B6935 Brivudine 25 mg 435.2 Nucleoside (thymidine) analog; DNA chain terminator, HSV-1 thymidine kinase inhibitor, HSP27 modulator. 5-[(E)-2-bromoethenyl]-1-[(2R,4S,5R)-4-hydroxy-5-(hydroxymethyl)oxolan-2-yl]-1,2,3,4-tetrahydropyrimidine-2,4-dione 69304-47-8 ≥98% 333.13 C11H13BrN2O5 C1C(C(OC1N2C=C(C(=O)NC2=O)C=CBr)CO)O Ambient Ambient "Heinrich JC, Tuukkanen A, Schroeder M, et al. RP101 (brivudine) binds to heat shock protein HSP27 (HSPB1) and enhances survival in animals and pancreatic cancer patients. J Cancer Res Clin Oncol. 2011 Sep;137(9):1349-61. PMID: 21833720.

 

Breuer M, De Loof A, Balzarini J, et al. Insecticidal activity of the pyrimidine nucleoside analogue (E)-5-(2-bromovinyl)-2'-deoxyuridine (BVDU). Pest Manag Sci. 2005 Aug;61(8):737-41. PMID: 15838935.

 

Spadari S, Ciarrocchi G, Focher F, et al. 5-Iodo-2'-deoxy-L-uridine and (E)-5-(2-bromovinyl)-2'-deoxy-L-uridine: selective phosphorylation by herpes simplex virus type 1 thymidine kinase, antiherpetic activity, and cytotoxicity studies. Mol Pharmacol. 1995 Jun;47(6):1231-8. PMID: 7603465.

 

Balzarini J, Bohman C, De Clercq E. Differential mechanism of cytostatic effect of (E)-5-(2-bromovinyl)-2'-deoxyuridine, 9-(1,3-dihydroxy-2-propoxymethyl)guanine, and other antiherpetic drugs on tumor cells transfected by the thymidine kinase gene of herpes simplex virus type 1 or type 2. J Biol Chem. 1993 Mar 25;268(9):6332-7. PMID: 8384209.

" Not dangerous goods.

LKT B6935 Brivudine 100 mg 1255.7 Nucleoside (thymidine) analog; DNA chain terminator, HSV-1 thymidine kinase inhibitor, HSP27 modulator. 5-[(E)-2-bromoethenyl]-1-[(2R,4S,5R)-4-hydroxy-5-(hydroxymethyl)oxolan-2-yl]-1,2,3,4-tetrahydropyrimidine-2,4-dione 69304-47-8 ≥98% 333.13 C11H13BrN2O5 C1C(C(OC1N2C=C(C(=O)NC2=O)C=CBr)CO)O Ambient Ambient "Heinrich JC, Tuukkanen A, Schroeder M, et al. RP101 (brivudine) binds to heat shock protein HSP27 (HSPB1) and enhances survival in animals and pancreatic cancer patients. J Cancer Res Clin Oncol. 2011 Sep;137(9):1349-61. PMID: 21833720.

 

Breuer M, De Loof A, Balzarini J, et al. Insecticidal activity of the pyrimidine nucleoside analogue (E)-5-(2-bromovinyl)-2'-deoxyuridine (BVDU). Pest Manag Sci. 2005 Aug;61(8):737-41. PMID: 15838935.

 

Spadari S, Ciarrocchi G, Focher F, et al. 5-Iodo-2'-deoxy-L-uridine and (E)-5-(2-bromovinyl)-2'-deoxy-L-uridine: selective phosphorylation by herpes simplex virus type 1 thymidine kinase, antiherpetic activity, and cytotoxicity studies. Mol Pharmacol. 1995 Jun;47(6):1231-8. PMID: 7603465.

 

Balzarini J, Bohman C, De Clercq E. Differential mechanism of cytostatic effect of (E)-5-(2-bromovinyl)-2'-deoxyuridine, 9-(1,3-dihydroxy-2-propoxymethyl)guanine, and other antiherpetic drugs on tumor cells transfected by the thymidine kinase gene of herpes simplex virus type 1 or type 2. J Biol Chem. 1993 Mar 25;268(9):6332-7. PMID: 8384209.

" Not dangerous goods.

LKT B6957 Bromhexine Hydrochloride 100 g 92.5 Synthetic derivative of vasicine, mucolytic. 2-Amino-3,5-dibromo-N-cyclohexyl-N-methyl- benzenemethanamine hydrochloride Auxit; Bisolvon; Ophtosol; Quentan 611-75-6 ≥98% 412.6 C14H20Br2N2 HCl CN(CC1=CC(=CC(=C1N)Br)Br)C2CCCCC2.Cl Ambient Ambient Slightly soluble in chloroform. Sparingly soluble in ethanol or methanol. "Winsel K, Grollmuss H, Unger U, et al. Modulation of alveolar macrophage activity by ambroxol, bromhexine and exogenous arachidonic acid. Z Erkr Atmungsorgane. 1985;165(2):149-62. PMID: 3002048.

 

Takeda H, Abe Y, Misawa M, et al. The role of vagal reflex in mechanism of secretagogic action of bromhexine. Jpn J Pharmacol. 1984 Aug;35(4):445-50. PMID: 6503040.

" Not dangerous goods.

LKT B6957 Bromhexine Hydrochloride 500 g 288.8 Synthetic derivative of vasicine, mucolytic. 2-Amino-3,5-dibromo-N-cyclohexyl-N-methyl- benzenemethanamine hydrochloride Auxit; Bisolvon; Ophtosol; Quentan 611-75-6 ≥98% 412.6 C14H20Br2N2 HCl CN(CC1=CC(=CC(=C1N)Br)Br)C2CCCCC2.Cl Ambient Ambient Slightly soluble in chloroform. Sparingly soluble in ethanol or methanol. "Winsel K, Grollmuss H, Unger U, et al. Modulation of alveolar macrophage activity by ambroxol, bromhexine and exogenous arachidonic acid. Z Erkr Atmungsorgane. 1985;165(2):149-62. PMID: 3002048.

 

Takeda H, Abe Y, Misawa M, et al. The role of vagal reflex in mechanism of secretagogic action of bromhexine. Jpn J Pharmacol. 1984 Aug;35(4):445-50. PMID: 6503040.

" Not dangerous goods.

LKT B6998 Bryostatin 1 10 µg 304.6 Macrolide lactone found in Bugula; TLR4 activator, PKC modulator. 83314-01-6 ≥98% 905.03 C47H68O17 CCCC=CC=CC(=O)OC1C(=CC(=O)OC)CC2CC(OC(=O)CC(CC3CC(C(C(O3)(CC4CC(=CC(=O)OC)CC(O4)C=CC(C1(O2)O)(C)C)O)(C)C)OC(=O)C)O)C(C)O Ambient -20°C Soluble in DMSO or ethanol. "Irie K, Yanagita RC. Synthesis and biological activities of simplified analogs of the natural PKC ligands, bryostatin-1 and aplysiatoxin. Chem Rec. 2014 Apr;14(2):251-67. PMID: 24677503.

 

Yi P, Schrott L, Castor TP, et al. Bryostatin-1 vs. TPPB: dose-dependent APP processing and PKC-α, -δ, and -ε isoform activation in SH-SY5Y neuronal cells. J Mol Neurosci. 2012 Sep;48(1):234-44. PMID: 22700373.

 

Hossain A, God JM, Radwan FF, et al. HLA class II defects in Burkitt lymphoma: bryostatin-1-induced 17 kDa protein restores CD4+ T-cell recognition. Clin Dev Immunol. 2011;2011:780839. PMID: 22162713.

 

Ariza ME, Ramakrishnan R, Singh NP, et al. Bryostatin-1, a naturally occurring antineoplastic agent, acts as a Toll-like receptor 4 (TLR-4) ligand and induces unique cytokines and chemokines in dendritic cells. J Biol Chem. 2011 Jan 7;286(1):24-34. PMID: 21036898.

 

Jaggi M, Chauhan SC, Du C, et al. Bryostatin 1 modulates beta-catenin subcellular localization and transcription activity through protein kinase D1 activation. Mol Cancer Ther. 2008 Sep;7(9):2703-12. Erratum in: Mol Cancer Ther. 2009 May;8(5):1398.  PMID: 18765827.

 

Kuzirian AM, Epstein HT, Gagliardi CJ, et al. Bryostatin enhancement of memory in Hermissenda. Biol Bull. 2006 Jun;210(3):201-14. PMID: 16801495.

" Not dangerous goods.

LKT W0269 (±)-Warfarin 1 g 22.5 Coumarin; VKORC1 inhibitor. coumadin 81-81-2 ≥98% 308.33 C19H16O4 CC(=O)CC(C1=CC=CC=C1)C2=C(C3=CC=CC=C3OC2=O)O Ambient Ambient Dioxane; Acetone Ether "Hall AM, Wilkins MR. Warfarin: a case history in pharmacogenetics. Heart. 2005 May;91(5):563-4. PMID: 15831631.

 

Tabrizi AR, Zehnbauer BA, Borecki IB, et al. The frequency and effects of cytochrome P450 (CYP) 2C9 polymorphisms in patients receiving warfarin. J Am Coll Surg. 2002 Mar;194(3):267-73. PMID: 11893129.

 

Freedman MD. Oral anticoagulants: pharmacodynamics, clinical indications and adverse effects. J Clin Pharmacol. 1992 Mar;32(3):196-209. PMID:1564123.

 

Wallin R, Martin LF. Vitamin K-dependent carboxylation and vitamin K metabolism in liver. Effects of warfarin. J Clin Invest. 1985 Nov;76(5):1879-84. PMID: 3932474.

 

Suttie JW. Mechanism of action of vitamin K: demonstration of a liver precursor of prothrombin. Science. 1973 Jan 12;179(4069):192-4. PMID: 4682251.

" T, Repr., N "UN number: 2811     Class: 6.1     Packing Group: I

Proper shipping name: Toxic solid, organic, n.o.s. (Warfarin)"

LKT W0269 (±)-Warfarin 10 g 109.2 Coumarin; VKORC1 inhibitor. coumadin 81-81-2 ≥98% 308.33 C19H16O4 CC(=O)CC(C1=CC=CC=C1)C2=C(C3=CC=CC=C3OC2=O)O Ambient Ambient Dioxane; Acetone Ether "Hall AM, Wilkins MR. Warfarin: a case history in pharmacogenetics. Heart. 2005 May;91(5):563-4. PMID: 15831631.

 

Tabrizi AR, Zehnbauer BA, Borecki IB, et al. The frequency and effects of cytochrome P450 (CYP) 2C9 polymorphisms in patients receiving warfarin. J Am Coll Surg. 2002 Mar;194(3):267-73. PMID: 11893129.

 

Freedman MD. Oral anticoagulants: pharmacodynamics, clinical indications and adverse effects. J Clin Pharmacol. 1992 Mar;32(3):196-209. PMID:1564123.

 

Wallin R, Martin LF. Vitamin K-dependent carboxylation and vitamin K metabolism in liver. Effects of warfarin. J Clin Invest. 1985 Nov;76(5):1879-84. PMID: 3932474.

 

Suttie JW. Mechanism of action of vitamin K: demonstration of a liver precursor of prothrombin. Science. 1973 Jan 12;179(4069):192-4. PMID: 4682251.

" T, Repr., N "UN number: 2811     Class: 6.1     Packing Group: I

Proper shipping name: Toxic solid, organic, n.o.s. (Warfarin)"

LKT W0269 (±)-Warfarin 25 g 218.4 Coumarin; VKORC1 inhibitor. coumadin 81-81-2 ≥98% 308.33 C19H16O4 CC(=O)CC(C1=CC=CC=C1)C2=C(C3=CC=CC=C3OC2=O)O Ambient Ambient Dioxane; Acetone Ether "Hall AM, Wilkins MR. Warfarin: a case history in pharmacogenetics. Heart. 2005 May;91(5):563-4. PMID: 15831631.

 

Tabrizi AR, Zehnbauer BA, Borecki IB, et al. The frequency and effects of cytochrome P450 (CYP) 2C9 polymorphisms in patients receiving warfarin. J Am Coll Surg. 2002 Mar;194(3):267-73. PMID: 11893129.

 

Freedman MD. Oral anticoagulants: pharmacodynamics, clinical indications and adverse effects. J Clin Pharmacol. 1992 Mar;32(3):196-209. PMID:1564123.

 

Wallin R, Martin LF. Vitamin K-dependent carboxylation and vitamin K metabolism in liver. Effects of warfarin. J Clin Invest. 1985 Nov;76(5):1879-84. PMID: 3932474.

 

Suttie JW. Mechanism of action of vitamin K: demonstration of a liver precursor of prothrombin. Science. 1973 Jan 12;179(4069):192-4. PMID: 4682251.

" T, Repr., N "UN number: 2811     Class: 6.1     Packing Group: I

Proper shipping name: Toxic solid, organic, n.o.s. (Warfarin)"

LKT B7058 Brompheniramine Maleate 10 mg 67.9 Pheniramine derivative; histamine H1 and mAChR antagonist, potential SERT and MAO-B inhibitor. ≥98% 435.31 C16H19BrN2 C4H4O4 CN(C)CCC(C1=CC=C(C=C1)Br)C2=CC=CC=N2.C(=CC(=O)O)C(=O)O Ambient Ambient "Egashira T, Takayama F, Yamanaka Y. The inhibition of monoamine oxidase activity by various antidepressants: differences found in various mammalian species. Jpn J Pharmacol. 1999 Sep;81(1):115-21. PMID: 10580379.

 

Yasuda SU, Yasuda RP. Affinities of brompheniramine, chlorpheniramine, and terfenadine at the five human muscarinic cholinergic receptor subtypes. Pharmacotherapy. 1999 Apr;19(4):447-51. PMID: 10212017.

 

Tatsumi M, Groshan K, Blakely RD, et al. Pharmacological profile of antidepressants and related compounds at human monoamine transporters. Eur J Pharmacol. 1997 Dec 11;340(2-3):249-58. PMID: 9537821.

 

Dachman WD, Bedarida G, Blaschke TF, et al. Histamine-induced venodilation in human beings involves both H1 and H2 receptor subtypes. J Allergy Clin Immunol. 1994 Mar;93(3):606-14. PMID: 8151062.

 

Ogren SO, Ross SB, Hall H, et al. The pharmacology of zimelidine: a 5-HT selective reuptake inhibitor. Acta Psychiatr Scand Suppl. 1981;290:127-51. PMID: 6452789.

" Not dangerous goods.

LKT B7058 Brompheniramine Maleate 25 mg 149.5 Pheniramine derivative; histamine H1 and mAChR antagonist, potential SERT and MAO-B inhibitor. ≥98% 435.31 C16H19BrN2 C4H4O4 CN(C)CCC(C1=CC=C(C=C1)Br)C2=CC=CC=N2.C(=CC(=O)O)C(=O)O Ambient Ambient "Egashira T, Takayama F, Yamanaka Y. The inhibition of monoamine oxidase activity by various antidepressants: differences found in various mammalian species. Jpn J Pharmacol. 1999 Sep;81(1):115-21. PMID: 10580379.

 

Yasuda SU, Yasuda RP. Affinities of brompheniramine, chlorpheniramine, and terfenadine at the five human muscarinic cholinergic receptor subtypes. Pharmacotherapy. 1999 Apr;19(4):447-51. PMID: 10212017.

 

Tatsumi M, Groshan K, Blakely RD, et al. Pharmacological profile of antidepressants and related compounds at human monoamine transporters. Eur J Pharmacol. 1997 Dec 11;340(2-3):249-58. PMID: 9537821.

 

Dachman WD, Bedarida G, Blaschke TF, et al. Histamine-induced venodilation in human beings involves both H1 and H2 receptor subtypes. J Allergy Clin Immunol. 1994 Mar;93(3):606-14. PMID: 8151062.

 

Ogren SO, Ross SB, Hall H, et al. The pharmacology of zimelidine: a 5-HT selective reuptake inhibitor. Acta Psychiatr Scand Suppl. 1981;290:127-51. PMID: 6452789.

" Not dangerous goods.

LKT B7058 Brompheniramine Maleate 100 mg 475.7 Pheniramine derivative; histamine H1 and mAChR antagonist, potential SERT and MAO-B inhibitor. ≥98% 435.31 C16H19BrN2 C4H4O4 CN(C)CCC(C1=CC=C(C=C1)Br)C2=CC=CC=N2.C(=CC(=O)O)C(=O)O Ambient Ambient "Egashira T, Takayama F, Yamanaka Y. The inhibition of monoamine oxidase activity by various antidepressants: differences found in various mammalian species. Jpn J Pharmacol. 1999 Sep;81(1):115-21. PMID: 10580379.

 

Yasuda SU, Yasuda RP. Affinities of brompheniramine, chlorpheniramine, and terfenadine at the five human muscarinic cholinergic receptor subtypes. Pharmacotherapy. 1999 Apr;19(4):447-51. PMID: 10212017.

 

Tatsumi M, Groshan K, Blakely RD, et al. Pharmacological profile of antidepressants and related compounds at human monoamine transporters. Eur J Pharmacol. 1997 Dec 11;340(2-3):249-58. PMID: 9537821.

 

Dachman WD, Bedarida G, Blaschke TF, et al. Histamine-induced venodilation in human beings involves both H1 and H2 receptor subtypes. J Allergy Clin Immunol. 1994 Mar;93(3):606-14. PMID: 8151062.

 

Ogren SO, Ross SB, Hall H, et al. The pharmacology of zimelidine: a 5-HT selective reuptake inhibitor. Acta Psychiatr Scand Suppl. 1981;290:127-51. PMID: 6452789.

" Not dangerous goods.

LKT T1849 Temozolomide 500 mg 849.3 Imidazotetrazine, DNA alkylator. 3,4-Dihydro-3-methyl-4-oxoimidazo[5,1-d]-1,2,3,5- tetrazine-8-carboxamide Methazolastone; Temodal; Temodar 85622-93-1 ≥98% 194.15 C6H6N6O2 CN1C(=O)N2C=NC(=C2N=N1)C(=O)N "Temozolomide was unstable at 37°C in human plasma with a degradation t1/2 of 15 min; however, it was stable at 4°C for at least 30 min. Temozolomide was stable in acidified human plasma (pH < 4) for at least 24 h at 25°C, and for at least 30 days at -20°C. Moreover, temozolomide was stable in acidified human plasma after being subjected to three freeze thaw cycles. 

J Pharm Biomed Anal. 2001 Jan;24(3):461-8" Ambient 4°C Soluble in DMSO to 39mg/mL, Water to 5 mg/mL, Ethanol <1mg/mL "Nagasawa DT, Chow F, Yew A, et al. Temozolomide and other potential agents for the treatment of glioblastoma multiforme. Neurosurg Clin N Am. 2012 Apr;23(2):307-22, ix. PMID: 22440874.

 

Wesolowski JR, Rajdev P, Mukherji SK. Temozolomide (Temodar). AJNR Am J Neuroradiol. 2010 Sep;31(8):1383-4. PMID: 2053882.

 

Friedman HS, Kerby T, Calvert H. Temozolomide and treatment of malignant glioma. Clin Cancer Res. 2000 Jul;6(7):2585-97. PMID: 10914698.

 

Horing E, Harter PN, Seznec J, et al. The “go or grow” potential of gliomas is linked to the necropeptide processing enzyme carboxypeptidase E and mediated by metabolic stress. Acta Neuropathol. 2012 Jul;124(1):83-97. PMID: 22249620.

 

Momiyama M, Suetsugu A, Chishima T, et al. Subcellular real-time imaging of the efficacy of temozolomide on cancer cells in the brain of live mice. Anticancer Res. 2013 Jan;33(1):103-106. PMID: 23267133.

" Repr., Carc., Muta., Xn, Xi Not dangerous goods.

LKT B8010 Buccalin 1 mg 72.1 Neuropeptide found in molluscs. "Glycyl-methionyl-aspartyl-seryl-leucyl-alanyl-phenylalanyl-

seryl-glycyl-glycyl-leucinamide" Buccalin A 116844-51-0 ≥95% 1053.2 C45H72N12O15S Ambient -20°C Soluble in water. "Veenstra JA. Neurohormones and neuropeptides encoded by the genome of Lottia gigantea, with reference to other mollusks and insects. Gen Comp Endocrinol. 2010 May 15;167(1):86-103. PMID: 20171220.

 

Vilim FS, Cropper EC, Rosen SC, et al. Structure, localization, and action of buccalin B: a bioactive peptide from Aplysia. Peptides. 1994;15(6):959-69. PMID: 7991459.

"

LKT B8010 Buccalin 2 mg 123.1 Neuropeptide found in molluscs. "Glycyl-methionyl-aspartyl-seryl-leucyl-alanyl-phenylalanyl-

seryl-glycyl-glycyl-leucinamide" Buccalin A 116844-51-0 ≥95% 1053.2 C45H72N12O15S Ambient -20°C Soluble in water. "Veenstra JA. Neurohormones and neuropeptides encoded by the genome of Lottia gigantea, with reference to other mollusks and insects. Gen Comp Endocrinol. 2010 May 15;167(1):86-103. PMID: 20171220.

 

Vilim FS, Cropper EC, Rosen SC, et al. Structure, localization, and action of buccalin B: a bioactive peptide from Aplysia. Peptides. 1994;15(6):959-69. PMID: 7991459.

"

LKT B8010 Buccalin 5 mg 216.1 Neuropeptide found in molluscs. "Glycyl-methionyl-aspartyl-seryl-leucyl-alanyl-phenylalanyl-

seryl-glycyl-glycyl-leucinamide" Buccalin A 116844-51-0 ≥95% 1053.2 C45H72N12O15S Ambient -20°C Soluble in water. "Veenstra JA. Neurohormones and neuropeptides encoded by the genome of Lottia gigantea, with reference to other mollusks and insects. Gen Comp Endocrinol. 2010 May 15;167(1):86-103. PMID: 20171220.

 

Vilim FS, Cropper EC, Rosen SC, et al. Structure, localization, and action of buccalin B: a bioactive peptide from Aplysia. Peptides. 1994;15(6):959-69. PMID: 7991459.

"

LKT G1745 Gemcitabine Hydrochloride 25 mg 95.1 Nucleoside (deoxycytidine) analog; ribonucleotide reductase inhibitor, DNA synthesis inhibitor. 2'-deoxy-2',2'-difluorocytidine monohydrochloride ((beta)-isomer) Gemzar 122111-03-9 ≥98% 299.66 C9H12ClF2N3O4 C1=CN(C(=O)N=C1N)C2C(C(C(O2)CO)O)(F)F.Cl In DMSO at +4 for 2 weeks at -80 for 6 months. Ambient Ambient Soluble in water. Slightly soluble in methanol, acetone, DMSO. "Chen SH, Li DL, Yang F, et al. Gemcitabine-induced pancreatic cancer cell death is associated with MST1/Cyclophilin D mitochondrial complexation. Biochimie. 2014 Apr 13. Epub ahead of print]. PMID: 24732633.

 

Su CH, Chu WC, Lan KH, et al. Gemcitabine causes telomere attrition by stabilizing TRF2. Eur J Cancer. 2012 Dec;48(18):3465-74. PMID: 22704123.

 

Greggs WM 3rd, Clouser CL, Patterson SE, et al. Discovery of drugs that possess activity against feline leukemia virus. J Gen Virol. 2012 Apr;93(Pt 4):900-5. PMID: 22258856.

 

Cerqueira NM, Fernandes PA, Ramos MJ. Understanding ribonucleotide reductase inactivation by gemcitabine. Chemistry. 2007;13(30):8507-15. PMID: 17636467.

 

Blackwood E, Epler J, Yen I, et al. Combination drug scheduling defines a “window of opportunity” for chemopotentiation of gemcitabine by an orally bioavailable, selective ChK1 inhibitor, GNE-900. Mol Cancer Ther. 2013 Oct;12(10):1968-1980. PMID: 23873850.

 

 

 

 

Reconstituted gemcitabine as the hydrochloride salt in the original vials is chemically stable at room temperature for 35 days but may develop crystals when stored at 4 degrees C. The crystals o not redissolve upon warming. Gemcitabine prepared as intravenous admixtures of 0.1 and 10 mg/mL as the hydrochloride salt in 5% dextrose injection and 0.9% sodium chloride injection in PVC bags and as a solution of 38 mg/mL in 0.9% sodium chloride injection packaged in plastic syringes is physically and chemically stable for at least 35 days at 4 degrees C and 23 degrees C. Gemcitabine as the hydrochloride salt is stable for at least 7 days at concentrations of 0.1, 10, and 38 mg/mL in 5% dextrose injection and 0.9% sodium chloride injection stored at 32 degrees C during simulated ambulatory infusion." Xn, T, T+, C, Xi, Muta. Cat. 2, Repr. Cat. Not dangerous goods.

LKT G1745 Gemcitabine Hydrochloride 100 mg 285.4 Nucleoside (deoxycytidine) analog; ribonucleotide reductase inhibitor, DNA synthesis inhibitor. 2'-deoxy-2',2'-difluorocytidine monohydrochloride ((beta)-isomer) Gemzar 122111-03-9 ≥98% 299.66 C9H12ClF2N3O4 C1=CN(C(=O)N=C1N)C2C(C(C(O2)CO)O)(F)F.Cl In DMSO at +4 for 2 weeks at -80 for 6 months. Ambient Ambient Soluble in water. Slightly soluble in methanol, acetone, DMSO. "Chen SH, Li DL, Yang F, et al. Gemcitabine-induced pancreatic cancer cell death is associated with MST1/Cyclophilin D mitochondrial complexation. Biochimie. 2014 Apr 13. Epub ahead of print]. PMID: 24732633.

 

Su CH, Chu WC, Lan KH, et al. Gemcitabine causes telomere attrition by stabilizing TRF2. Eur J Cancer. 2012 Dec;48(18):3465-74. PMID: 22704123.

 

Greggs WM 3rd, Clouser CL, Patterson SE, et al. Discovery of drugs that possess activity against feline leukemia virus. J Gen Virol. 2012 Apr;93(Pt 4):900-5. PMID: 22258856.

 

Cerqueira NM, Fernandes PA, Ramos MJ. Understanding ribonucleotide reductase inactivation by gemcitabine. Chemistry. 2007;13(30):8507-15. PMID: 17636467.

 

Blackwood E, Epler J, Yen I, et al. Combination drug scheduling defines a “window of opportunity” for chemopotentiation of gemcitabine by an orally bioavailable, selective ChK1 inhibitor, GNE-900. Mol Cancer Ther. 2013 Oct;12(10):1968-1980. PMID: 23873850.

 

 

 

 

Reconstituted gemcitabine as the hydrochloride salt in the original vials is chemically stable at room temperature for 35 days but may develop crystals when stored at 4 degrees C. The crystals o not redissolve upon warming. Gemcitabine prepared as intravenous admixtures of 0.1 and 10 mg/mL as the hydrochloride salt in 5% dextrose injection and 0.9% sodium chloride injection in PVC bags and as a solution of 38 mg/mL in 0.9% sodium chloride injection packaged in plastic syringes is physically and chemically stable for at least 35 days at 4 degrees C and 23 degrees C. Gemcitabine as the hydrochloride salt is stable for at least 7 days at concentrations of 0.1, 10, and 38 mg/mL in 5% dextrose injection and 0.9% sodium chloride injection stored at 32 degrees C during simulated ambulatory infusion." Xn, T, T+, C, Xi, Muta. Cat. 2, Repr. Cat. Not dangerous goods.

LKT B8112 Budesonide 100 mg 65.6 Steroid; glucocorticoid agonist. 51333-22-3 ≥97% 430.53 C25H34O6 CCCC1OC2CC3C4CCC5=CC(=O)C=CC5(C4C(CC3(C2(O1)C(=O)CO)C)O)C Ambient 4°C "Deng X, Zhang Z, Gu W, et al. Budesonide inhibits interleukin-32 expression in a rat model of chronic obstructive pulmonary disease. Exp Lung Res. 2012 Aug;38(6):295-301. PMID: 22646473.

 

Orta ML, Domínguez I, Pastor N, et al. The role of the DNA hypermethylating agent Budesonide in the decatenating activity of DNA topoisomerase II. Mutat Res. 2010 Dec 10;694(1-2):45-52. PMID: 20883705.

 

Chen YJ, Wang T, Liu DS, et al. Effect of budesonide on TGF-beta1-enhanced VEGF production by lung fibroblasts. Cell Biol Int. 2010 Jul;34(7):777-82. PMID: 20359293.

 

Ewing P, Ryrfeldt A, Sjöberg CO, et al. Vasoconstriction after inhalation of budesonide: a study in the isolated and perfused rat lung. Pulm Pharmacol Ther. 2010 Feb;23(1):9-14. PMID: 19800019.

" Carc., Xi, Xn Not dangerous goods.

LKT B8112 Budesonide 250 mg 187.4 Steroid; glucocorticoid agonist. 51333-22-3 ≥97% 430.53 C25H34O6 CCCC1OC2CC3C4CCC5=CC(=O)C=CC5(C4C(CC3(C2(O1)C(=O)CO)C)O)C Ambient 4°C "Deng X, Zhang Z, Gu W, et al. Budesonide inhibits interleukin-32 expression in a rat model of chronic obstructive pulmonary disease. Exp Lung Res. 2012 Aug;38(6):295-301. PMID: 22646473.

 

Orta ML, Domínguez I, Pastor N, et al. The role of the DNA hypermethylating agent Budesonide in the decatenating activity of DNA topoisomerase II. Mutat Res. 2010 Dec 10;694(1-2):45-52. PMID: 20883705.

 

Chen YJ, Wang T, Liu DS, et al. Effect of budesonide on TGF-beta1-enhanced VEGF production by lung fibroblasts. Cell Biol Int. 2010 Jul;34(7):777-82. PMID: 20359293.

 

Ewing P, Ryrfeldt A, Sjöberg CO, et al. Vasoconstriction after inhalation of budesonide: a study in the isolated and perfused rat lung. Pulm Pharmacol Ther. 2010 Feb;23(1):9-14. PMID: 19800019.

" Carc., Xi, Xn Not dangerous goods.

LKT B8112 Budesonide 1 g 525 Steroid; glucocorticoid agonist. 51333-22-3 ≥97% 430.53 C25H34O6 CCCC1OC2CC3C4CCC5=CC(=O)C=CC5(C4C(CC3(C2(O1)C(=O)CO)C)O)C Ambient 4°C "Deng X, Zhang Z, Gu W, et al. Budesonide inhibits interleukin-32 expression in a rat model of chronic obstructive pulmonary disease. Exp Lung Res. 2012 Aug;38(6):295-301. PMID: 22646473.

 

Orta ML, Domínguez I, Pastor N, et al. The role of the DNA hypermethylating agent Budesonide in the decatenating activity of DNA topoisomerase II. Mutat Res. 2010 Dec 10;694(1-2):45-52. PMID: 20883705.

 

Chen YJ, Wang T, Liu DS, et al. Effect of budesonide on TGF-beta1-enhanced VEGF production by lung fibroblasts. Cell Biol Int. 2010 Jul;34(7):777-82. PMID: 20359293.

 

Ewing P, Ryrfeldt A, Sjöberg CO, et al. Vasoconstriction after inhalation of budesonide: a study in the isolated and perfused rat lung. Pulm Pharmacol Ther. 2010 Feb;23(1):9-14. PMID: 19800019.

" Carc., Xi, Xn Not dangerous goods.

LKT B8144 Bulleyaconitine A 10 mg 68.8 Found in Aconitum bulleyanum; voltage-gated Na+ channel blocker. 107668-79-1 ≥96% 627.76 C35H49NO9 CCN1CC2(CCC(C34C2C(C(C31)C5(CC(C6(CC4C5C6C(=O)C7=CC=C(C=C7)OC)O)OC)OC(=O)C)OC)OC)COC Ambient 4°C Soluble in ethyl ether and alcohol. Insoluble in water. "Wang CF, Gerner P, Schmidt B, et al. Use of bulleyaconitine A as an adjuvant for prolonged cutaneous analgesia in the rat. Anesth Analg. 2008 Oct;107(4):1397-405. PMID: 18806059.

 

Wang CF, Gerner P, Wang SY, et al. Bulleyaconitine A isolated from aconitum plant displays long-acting local anesthetic properties in vitro and in vivo. Anesthesiology. 2007 Jul;107(1):82-90. PMID: 17585219.

 

Catterall WA, Gainer M. Interaction of brevetoxin A with a new receptor site on the sodium channel. Toxicon. 1985;23(3):497-504. PMID: 2411017.

" T Not dangerous goods.

LKT B8144 Bulleyaconitine A 100 mg 401.1 Found in Aconitum bulleyanum; voltage-gated Na+ channel blocker. 107668-79-1 ≥96% 627.76 C35H49NO9 CCN1CC2(CCC(C34C2C(C(C31)C5(CC(C6(CC4C5C6C(=O)C7=CC=C(C=C7)OC)O)OC)OC(=O)C)OC)OC)COC Ambient 4°C Soluble in ethyl ether and alcohol. Insoluble in water. "Wang CF, Gerner P, Schmidt B, et al. Use of bulleyaconitine A as an adjuvant for prolonged cutaneous analgesia in the rat. Anesth Analg. 2008 Oct;107(4):1397-405. PMID: 18806059.

 

Wang CF, Gerner P, Wang SY, et al. Bulleyaconitine A isolated from aconitum plant displays long-acting local anesthetic properties in vitro and in vivo. Anesthesiology. 2007 Jul;107(1):82-90. PMID: 17585219.

 

Catterall WA, Gainer M. Interaction of brevetoxin A with a new receptor site on the sodium channel. Toxicon. 1985;23(3):497-504. PMID: 2411017.

" T Not dangerous goods.

LKT B8174 Butylated Hydroxyanisole 50 g 43.5 Commercial food additive, antioxidant. (1,1-Dimethylethyl)-4-methoxyphenol BHA; Antrancine 12; Embanox; Nipantiox 1-F; Sustane 1-F; Tenox BHA 25013-16-5 ≥96% 180.24 C11H16O2 CC(C)(C)C1=C(C=CC(=C1)OC)O Ambient Ambient Soluble in >50% alcohol, ethanol (150 mg/mL), propylene glycol, fats or oils. Insoluble in water. "Singh B, Bhat HK. Superoxide dismutase 3 is induced by antioxidants, inhibits oxidative DNA damage and is associated with inhibition of estrogen-induced breast cancer. Carcinogenesis. 2012 Dec;33(12):2601-10. PMID: 23027624.

 

Criado S, Allevi C, Ceballos C, et al. Visible-light promoted degradation of the commercial antioxidants butylated hydroxyanisole (BHA) and butylated hydroxytoluene (BHT): a kinetic study. Redox Rep. 2007;12(6):282-8. PMID: 17961300.

" Carc., Xi, Xn Not dangerous goods.

LKT B8174 Butylated Hydroxyanisole 100 g 63.3 Commercial food additive, antioxidant. (1,1-Dimethylethyl)-4-methoxyphenol BHA; Antrancine 12; Embanox; Nipantiox 1-F; Sustane 1-F; Tenox BHA 25013-16-5 ≥96% 180.24 C11H16O2 CC(C)(C)C1=C(C=CC(=C1)OC)O Ambient Ambient Soluble in >50% alcohol, ethanol (150 mg/mL), propylene glycol, fats or oils. Insoluble in water. "Singh B, Bhat HK. Superoxide dismutase 3 is induced by antioxidants, inhibits oxidative DNA damage and is associated with inhibition of estrogen-induced breast cancer. Carcinogenesis. 2012 Dec;33(12):2601-10. PMID: 23027624.

 

Criado S, Allevi C, Ceballos C, et al. Visible-light promoted degradation of the commercial antioxidants butylated hydroxyanisole (BHA) and butylated hydroxytoluene (BHT): a kinetic study. Redox Rep. 2007;12(6):282-8. PMID: 17961300.

" Carc., Xi, Xn Not dangerous goods.

LKT B8248 Bumetanide 250 mg 75 Loop diuretic; NKCC symporter and KCC2 co-transporter inhibitor, potential GABA-A antagonist. 3-(butylamino)-4-phenoxy-5-sulfamoylbenzoic acid 28395-03-1 ≥98% 364.42 C17H20N2O5S CCCCNC1=C(C(=CC(=C1)C(=O)O)S(=O)(=O)N)OC2=CC=CC=C2 Ambient Ambient Ethanol, DMSO "Wang T, Yang YQ, Karasawa T, et al. Bumetanide hyperpolarizes madin-darby canine kidney cells and enhances cellular gentamicin uptake by elevating cytosolic Ca(2+) thus facilitating intermediate conductance Ca(2+)--activated potassium channels. Cell Biochem Biophys. 2013 Apr;65(3):381-98. PMID: 23109177.

 

Krystal AD, Sutherland J, Hochman DW. Loop diuretics have anxiolytic effects in rat models of conditioned anxiety. PLoS One. 2012;7(4):e35417. PMID: 22514741.

 

Shulga A, Magalhães AC, Autio H, et al. The loop diuretic bumetanide blocks posttraumatic p75NTR upregulation and rescues injured neurons. J Neurosci. 2012 Feb 1;32(5):1757-70. PMID: 22302815.

 

Dzhala VI, Kuchibhotla KV, Glykys JC, et al. Progressive NKCC1-dependent neuronal chloride accumulation during neonatal seizures. J Neurosci. 2010 Sep 1;30(35):11745-61. PMID: 20810895.

 

Feig PU. Cellular mechanism of action of loop diuretics: implications for drug effectiveness and adverse effects. Am J Cardiol. 1986 Jan 24;57(2):14A-19A. PMID: 3511652.

" Xn, T Not dangerous goods.

LKT B8248 Bumetanide 1 g 206.3 Loop diuretic; NKCC symporter and KCC2 co-transporter inhibitor, potential GABA-A antagonist. 3-(butylamino)-4-phenoxy-5-sulfamoylbenzoic acid 28395-03-1 ≥98% 364.42 C17H20N2O5S CCCCNC1=C(C(=CC(=C1)C(=O)O)S(=O)(=O)N)OC2=CC=CC=C2 Ambient Ambient Ethanol, DMSO "Wang T, Yang YQ, Karasawa T, et al. Bumetanide hyperpolarizes madin-darby canine kidney cells and enhances cellular gentamicin uptake by elevating cytosolic Ca(2+) thus facilitating intermediate conductance Ca(2+)--activated potassium channels. Cell Biochem Biophys. 2013 Apr;65(3):381-98. PMID: 23109177.

 

Krystal AD, Sutherland J, Hochman DW. Loop diuretics have anxiolytic effects in rat models of conditioned anxiety. PLoS One. 2012;7(4):e35417. PMID: 22514741.

 

Shulga A, Magalhães AC, Autio H, et al. The loop diuretic bumetanide blocks posttraumatic p75NTR upregulation and rescues injured neurons. J Neurosci. 2012 Feb 1;32(5):1757-70. PMID: 22302815.

 

Dzhala VI, Kuchibhotla KV, Glykys JC, et al. Progressive NKCC1-dependent neuronal chloride accumulation during neonatal seizures. J Neurosci. 2010 Sep 1;30(35):11745-61. PMID: 20810895.

 

Feig PU. Cellular mechanism of action of loop diuretics: implications for drug effectiveness and adverse effects. Am J Cardiol. 1986 Jan 24;57(2):14A-19A. PMID: 3511652.

" Xn, T Not dangerous goods.

LKT B8261 Bupivacaine 1 g 54.4 BK/SK, Kv1, Kv3, TASK-2 K+ channel blocker, voltage-gated Na+ channel blocker. 1-butyl-N-(2,6-dimethylphenyl)piperidine-2-carboxamide 38396-39-3 ≥98% 288.43 C18H28N2O CCCCN1CCCCC1C(=O)NC2=C(C=CC=C2C)C Ambient Ambient "Harato M, Huang L, Kondo F, et al. Bupivacaine-induced apoptosis independently of WDR35 expression in mouse neuroblastoma Neuro2a cells. BMC Neurosci. 2012 Dec 10;13:149. PMID: 23227925.

 

Martín P, Enrique N, Palomo AR, et al. Bupivacaine inhibits large conductance, voltage- and Ca2+- activated K+ channels in human umbilical artery smooth muscle cells. Channels (Austin). 2012 May-Jun;6(3):174-80. PMID: 22688134.

 

Lu J, Xu SY, Zhang QG, et al. Bupivacaine induces apoptosis via mitochondria and p38 MAPK dependent pathways. Eur J Pharmacol. 2011 Apr 25;657(1-3):51-8. PMID: 21315711.

 

Cela O, Piccoli C, Scrima R, et al. Bupivacaine uncouples the mitochondrial oxidative phosphorylation, inhibits respiratory chain complexes I and III and enhances ROS production: results of a study on cell cultures. Mitochondrion. 2010 Aug;10(5):487-96. PMID: 20546950.

 

Nilsson J, Madeja M, Elinder F, et al. Bupivacaine blocks N-type inactivating Kv channels in the open state: no allosteric effect on inactivation kinetics. Biophys J. 2008 Dec;95(11):5138-52. PMID: 18790854.

 

Kindler CH, Paul M, Zou H, et al. Amide local anesthetics potently inhibit the human tandem pore domain background K+ channel TASK-2 (KCNK5). J Pharmacol Exp Ther. 2003 Jul;306(1):84-92. PMID: 12660311.

" "UN number: 2811     Class: 6.1     Packing Group: II

Proper shipping name: Toxic solid, organic, n.o.s. (Bupivacaine)"

LKT B8261 Bupivacaine 5 g 136 BK/SK, Kv1, Kv3, TASK-2 K+ channel blocker, voltage-gated Na+ channel blocker. 1-butyl-N-(2,6-dimethylphenyl)piperidine-2-carboxamide 38396-39-3 ≥98% 288.43 C18H28N2O CCCCN1CCCCC1C(=O)NC2=C(C=CC=C2C)C Ambient Ambient "Harato M, Huang L, Kondo F, et al. Bupivacaine-induced apoptosis independently of WDR35 expression in mouse neuroblastoma Neuro2a cells. BMC Neurosci. 2012 Dec 10;13:149. PMID: 23227925.

 

Martín P, Enrique N, Palomo AR, et al. Bupivacaine inhibits large conductance, voltage- and Ca2+- activated K+ channels in human umbilical artery smooth muscle cells. Channels (Austin). 2012 May-Jun;6(3):174-80. PMID: 22688134.

 

Lu J, Xu SY, Zhang QG, et al. Bupivacaine induces apoptosis via mitochondria and p38 MAPK dependent pathways. Eur J Pharmacol. 2011 Apr 25;657(1-3):51-8. PMID: 21315711.

 

Cela O, Piccoli C, Scrima R, et al. Bupivacaine uncouples the mitochondrial oxidative phosphorylation, inhibits respiratory chain complexes I and III and enhances ROS production: results of a study on cell cultures. Mitochondrion. 2010 Aug;10(5):487-96. PMID: 20546950.

 

Nilsson J, Madeja M, Elinder F, et al. Bupivacaine blocks N-type inactivating Kv channels in the open state: no allosteric effect on inactivation kinetics. Biophys J. 2008 Dec;95(11):5138-52. PMID: 18790854.

 

Kindler CH, Paul M, Zou H, et al. Amide local anesthetics potently inhibit the human tandem pore domain background K+ channel TASK-2 (KCNK5). J Pharmacol Exp Ther. 2003 Jul;306(1):84-92. PMID: 12660311.

" "UN number: 2811     Class: 6.1     Packing Group: II

Proper shipping name: Toxic solid, organic, n.o.s. (Bupivacaine)"

LKT B8261 Bupivacaine 25 g 407.7 BK/SK, Kv1, Kv3, TASK-2 K+ channel blocker, voltage-gated Na+ channel blocker. 1-butyl-N-(2,6-dimethylphenyl)piperidine-2-carboxamide 38396-39-3 ≥98% 288.43 C18H28N2O CCCCN1CCCCC1C(=O)NC2=C(C=CC=C2C)C Ambient Ambient "Harato M, Huang L, Kondo F, et al. Bupivacaine-induced apoptosis independently of WDR35 expression in mouse neuroblastoma Neuro2a cells. BMC Neurosci. 2012 Dec 10;13:149. PMID: 23227925.

 

Martín P, Enrique N, Palomo AR, et al. Bupivacaine inhibits large conductance, voltage- and Ca2+- activated K+ channels in human umbilical artery smooth muscle cells. Channels (Austin). 2012 May-Jun;6(3):174-80. PMID: 22688134.

 

Lu J, Xu SY, Zhang QG, et al. Bupivacaine induces apoptosis via mitochondria and p38 MAPK dependent pathways. Eur J Pharmacol. 2011 Apr 25;657(1-3):51-8. PMID: 21315711.

 

Cela O, Piccoli C, Scrima R, et al. Bupivacaine uncouples the mitochondrial oxidative phosphorylation, inhibits respiratory chain complexes I and III and enhances ROS production: results of a study on cell cultures. Mitochondrion. 2010 Aug;10(5):487-96. PMID: 20546950.

 

Nilsson J, Madeja M, Elinder F, et al. Bupivacaine blocks N-type inactivating Kv channels in the open state: no allosteric effect on inactivation kinetics. Biophys J. 2008 Dec;95(11):5138-52. PMID: 18790854.

 

Kindler CH, Paul M, Zou H, et al. Amide local anesthetics potently inhibit the human tandem pore domain background K+ channel TASK-2 (KCNK5). J Pharmacol Exp Ther. 2003 Jul;306(1):84-92. PMID: 12660311.

" "UN number: 2811     Class: 6.1     Packing Group: II

Proper shipping name: Toxic solid, organic, n.o.s. (Bupivacaine)"

LKT B8262 Bupivacaine Hydrochloride Monohydrate 1 g 46.4 Amino amide; voltage-gated Na+, BK/SK, Kv1, Kv3, TASK-2 K+ channel inhibitor. 1-Butyl-N-(2,6-dimethylphenyl)-2-piperidinecarboxamide hydrochloride hydrate Bupivacaine hydrochloride monohydrate; Carbostesin; Marcaine; Sensorcaine 73360-54-0 ≥98% 342.91 C18H28N2O HCl H2O CCCCN1CCCCC1C(=O)NC2=C(C=CC=C2C)C.O.Cl Ambient Ambient Soluble in water. Slightly soluble in acetone, chloroform and ether. "Harato M, Huang L, Kondo F, et al. Bupivacaine-induced apoptosis independently of WDR35 expression in mouse neuroblastoma Neuro2a cells. BMC Neurosci. 2012 Dec 10;13:149. PMID: 23227925.

 

Martín P, Enrique N, Palomo AR, et al. Bupivacaine inhibits large conductance, voltage- and Ca2+- activated K+ channels in human umbilical artery smooth muscle cells. Channels (Austin). 2012 May-Jun;6(3):174-80. PMID: 22688134.

 

Lu J, Xu SY, Zhang QG, et al. Bupivacaine induces apoptosis via mitochondria and p38 MAPK dependent pathways. Eur J Pharmacol. 2011 Apr 25;657(1-3):51-8. PMID: 21315711.

 

Cela O, Piccoli C, Scrima R, et al. Bupivacaine uncouples the mitochondrial oxidative phosphorylation, inhibits respiratory chain complexes I and III and enhances ROS production: results of a study on cell cultures. Mitochondrion. 2010 Aug;10(5):487-96. PMID: 20546950.

 

Nilsson J, Madeja M, Elinder F, et al. Bupivacaine blocks N-type inactivating Kv channels in the open state: no allosteric effect on inactivation kinetics. Biophys J. 2008 Dec;95(11):5138-52. PMID: 18790854.

 

Kindler CH, Paul M, Zou H, et al. Amide local anesthetics potently inhibit the human tandem pore domain background K+ channel TASK-2 (KCNK5). J Pharmacol Exp Ther. 2003 Jul;306(1):84-92. PMID: 12660311.

" T+ "UN number: 2811     Class:  6.1     Packing group:  II

Proper shipping name:  Toxic solids, organic, n.o.s. (Bupivacaine hydrochloride)

Marine pollutant:  No     Poison inhalation hazard:  No"

LKT B8262 Bupivacaine Hydrochloride Monohydrate 5 g 136 Amino amide; voltage-gated Na+, BK/SK, Kv1, Kv3, TASK-2 K+ channel inhibitor. 1-Butyl-N-(2,6-dimethylphenyl)-2-piperidinecarboxamide hydrochloride hydrate Bupivacaine hydrochloride monohydrate; Carbostesin; Marcaine; Sensorcaine 73360-54-0 ≥98% 342.91 C18H28N2O HCl H2O CCCCN1CCCCC1C(=O)NC2=C(C=CC=C2C)C.O.Cl Ambient Ambient Soluble in water. Slightly soluble in acetone, chloroform and ether. "Harato M, Huang L, Kondo F, et al. Bupivacaine-induced apoptosis independently of WDR35 expression in mouse neuroblastoma Neuro2a cells. BMC Neurosci. 2012 Dec 10;13:149. PMID: 23227925.

 

Martín P, Enrique N, Palomo AR, et al. Bupivacaine inhibits large conductance, voltage- and Ca2+- activated K+ channels in human umbilical artery smooth muscle cells. Channels (Austin). 2012 May-Jun;6(3):174-80. PMID: 22688134.

 

Lu J, Xu SY, Zhang QG, et al. Bupivacaine induces apoptosis via mitochondria and p38 MAPK dependent pathways. Eur J Pharmacol. 2011 Apr 25;657(1-3):51-8. PMID: 21315711.

 

Cela O, Piccoli C, Scrima R, et al. Bupivacaine uncouples the mitochondrial oxidative phosphorylation, inhibits respiratory chain complexes I and III and enhances ROS production: results of a study on cell cultures. Mitochondrion. 2010 Aug;10(5):487-96. PMID: 20546950.

 

Nilsson J, Madeja M, Elinder F, et al. Bupivacaine blocks N-type inactivating Kv channels in the open state: no allosteric effect on inactivation kinetics. Biophys J. 2008 Dec;95(11):5138-52. PMID: 18790854.

 

Kindler CH, Paul M, Zou H, et al. Amide local anesthetics potently inhibit the human tandem pore domain background K+ channel TASK-2 (KCNK5). J Pharmacol Exp Ther. 2003 Jul;306(1):84-92. PMID: 12660311.

" T+ "UN number: 2811     Class:  6.1     Packing group:  II

Proper shipping name:  Toxic solids, organic, n.o.s. (Bupivacaine hydrochloride)

Marine pollutant:  No     Poison inhalation hazard:  No"

LKT B8262 Bupivacaine Hydrochloride Monohydrate 25 g 475.7 Amino amide; voltage-gated Na+, BK/SK, Kv1, Kv3, TASK-2 K+ channel inhibitor. 1-Butyl-N-(2,6-dimethylphenyl)-2-piperidinecarboxamide hydrochloride hydrate Bupivacaine hydrochloride monohydrate; Carbostesin; Marcaine; Sensorcaine 73360-54-0 ≥98% 342.91 C18H28N2O HCl H2O CCCCN1CCCCC1C(=O)NC2=C(C=CC=C2C)C.O.Cl Ambient Ambient Soluble in water. Slightly soluble in acetone, chloroform and ether. "Harato M, Huang L, Kondo F, et al. Bupivacaine-induced apoptosis independently of WDR35 expression in mouse neuroblastoma Neuro2a cells. BMC Neurosci. 2012 Dec 10;13:149. PMID: 23227925.

 

Martín P, Enrique N, Palomo AR, et al. Bupivacaine inhibits large conductance, voltage- and Ca2+- activated K+ channels in human umbilical artery smooth muscle cells. Channels (Austin). 2012 May-Jun;6(3):174-80. PMID: 22688134.

 

Lu J, Xu SY, Zhang QG, et al. Bupivacaine induces apoptosis via mitochondria and p38 MAPK dependent pathways. Eur J Pharmacol. 2011 Apr 25;657(1-3):51-8. PMID: 21315711.

 

Cela O, Piccoli C, Scrima R, et al. Bupivacaine uncouples the mitochondrial oxidative phosphorylation, inhibits respiratory chain complexes I and III and enhances ROS production: results of a study on cell cultures. Mitochondrion. 2010 Aug;10(5):487-96. PMID: 20546950.

 

Nilsson J, Madeja M, Elinder F, et al. Bupivacaine blocks N-type inactivating Kv channels in the open state: no allosteric effect on inactivation kinetics. Biophys J. 2008 Dec;95(11):5138-52. PMID: 18790854.

 

Kindler CH, Paul M, Zou H, et al. Amide local anesthetics potently inhibit the human tandem pore domain background K+ channel TASK-2 (KCNK5). J Pharmacol Exp Ther. 2003 Jul;306(1):84-92. PMID: 12660311.

" T+ "UN number: 2811     Class:  6.1     Packing group:  II

Proper shipping name:  Toxic solids, organic, n.o.s. (Bupivacaine hydrochloride)

Marine pollutant:  No     Poison inhalation hazard:  No"

LKT L1784 Levetiracetam 100 mg 65.6 SV2A synaptic vesicle inhibitor. 2(S)-(2-oxopyrrolidin-1-yl)butyramide 102767-28-2 ≥98% 170.21 C8H14N2O2 CCC(C(=O)N)N1CCCC1=O Ambient Ambient Soluble in DMSO, water, and ethanol, all to 34mg/mL "Vogl C, Mochida S, Wolff C, et al. The synaptic vesicle glycoprotein 2A ligand levetiracetam inhibits presynaptic Ca2+ channels through an intracellular pathway. Mol Pharmacol. 2012 Aug;82(2):199-208. PMID: 22554805.

 

Sanchez PE, Zhu L, Verret L, et al. Levetiracetam suppresses neuronal network dysfunction and reverses synaptic and cognitive deficits in an Alzheimer's disease model. Proc Natl Acad Sci U S A. 2012 Oct 16;109(42):E2895-903. PMID: 22869752.

 

Farooq MU, Bhatt A, Majid A, et al. Levetiracetam for managing neurologic and psychiatric disorders. Am J Health Syst Pharm. 2009 Mar 15;66(6):541-61. PMID: 19265183.

 

Lynch BA, Lambeng N, Nocka K, et al. The synaptic vesicle protein SV2A is the binding site for the antiepileptic drug levetiracetam. Proc Natl Acad Sci U S A. 2004 Jun 29;101(26):9861-6. PMID: 15210974.

" Xn Not dangerous goods.

LKT L1784 Levetiracetam 250 mg 121.9 SV2A synaptic vesicle inhibitor. 2(S)-(2-oxopyrrolidin-1-yl)butyramide 102767-28-2 ≥98% 170.21 C8H14N2O2 CCC(C(=O)N)N1CCCC1=O Ambient Ambient Soluble in DMSO, water, and ethanol, all to 34mg/mL "Vogl C, Mochida S, Wolff C, et al. The synaptic vesicle glycoprotein 2A ligand levetiracetam inhibits presynaptic Ca2+ channels through an intracellular pathway. Mol Pharmacol. 2012 Aug;82(2):199-208. PMID: 22554805.

 

Sanchez PE, Zhu L, Verret L, et al. Levetiracetam suppresses neuronal network dysfunction and reverses synaptic and cognitive deficits in an Alzheimer's disease model. Proc Natl Acad Sci U S A. 2012 Oct 16;109(42):E2895-903. PMID: 22869752.

 

Farooq MU, Bhatt A, Majid A, et al. Levetiracetam for managing neurologic and psychiatric disorders. Am J Health Syst Pharm. 2009 Mar 15;66(6):541-61. PMID: 19265183.

 

Lynch BA, Lambeng N, Nocka K, et al. The synaptic vesicle protein SV2A is the binding site for the antiepileptic drug levetiracetam. Proc Natl Acad Sci U S A. 2004 Jun 29;101(26):9861-6. PMID: 15210974.

" Xn Not dangerous goods.

LKT L1784 Levetiracetam 1 g 337.6 SV2A synaptic vesicle inhibitor. 2(S)-(2-oxopyrrolidin-1-yl)butyramide 102767-28-2 ≥98% 170.21 C8H14N2O2 CCC(C(=O)N)N1CCCC1=O Ambient Ambient Soluble in DMSO, water, and ethanol, all to 34mg/mL "Vogl C, Mochida S, Wolff C, et al. The synaptic vesicle glycoprotein 2A ligand levetiracetam inhibits presynaptic Ca2+ channels through an intracellular pathway. Mol Pharmacol. 2012 Aug;82(2):199-208. PMID: 22554805.

 

Sanchez PE, Zhu L, Verret L, et al. Levetiracetam suppresses neuronal network dysfunction and reverses synaptic and cognitive deficits in an Alzheimer's disease model. Proc Natl Acad Sci U S A. 2012 Oct 16;109(42):E2895-903. PMID: 22869752.

 

Farooq MU, Bhatt A, Majid A, et al. Levetiracetam for managing neurologic and psychiatric disorders. Am J Health Syst Pharm. 2009 Mar 15;66(6):541-61. PMID: 19265183.

 

Lynch BA, Lambeng N, Nocka K, et al. The synaptic vesicle protein SV2A is the binding site for the antiepileptic drug levetiracetam. Proc Natl Acad Sci U S A. 2004 Jun 29;101(26):9861-6. PMID: 15210974.

" Xn Not dangerous goods.

LKT G0278 Gatifloxacin Sesquihydrate 500 mg 47.6 Fluoroquinolone; bacterial DNA gyrase inhibitor. 1-Cyclopropyl-6-fluoro-1,4-dihydro-8-methoxy-7-(3-methyl-1-piperazinyl)-4-oxo-3-quinolinecarboxylic acid Tequin 180200-66-2 ≥98% 402.42 C19H22FN3O4  3/2H2O CC1CN(CCN1)C2=C(C=C3C(=C2OC)N(C=C(C3=O)C(=O)O)C4CC4)F Ambient Ambient Soluble in water (40-60 mg/mL) at a pH of 2 to 5. "Pantel A, Petrella S, Veziris N, et al. Extending the definition of the GyrB quinolone resistance-determining region in Mycobacterium tuberculosis DNA gyrase for assessing fluoroquinolone resistance in M. tuberculosis. Antimicrob Agents Chemother. 2012 Apr;56(4):1990-6. PMID: 22290942.

 

Croisier D, Etienne M, Piroth L, et al. In vivo pharmacodynamic efficacy of gatifloxacin against Streptococcus pneumoniae in an experimental model of pneumonia: impact of the low levels of fluoroquinolone resistance on the enrichment of resistant mutants. J Antimicrob Chemother. 2004 Sep;54(3):640-7. PMID: 15317743.

" Xn Not dangerous goods.

LKT G0278 Gatifloxacin Sesquihydrate 1 g 74.8 Fluoroquinolone; bacterial DNA gyrase inhibitor. 1-Cyclopropyl-6-fluoro-1,4-dihydro-8-methoxy-7-(3-methyl-1-piperazinyl)-4-oxo-3-quinolinecarboxylic acid Tequin 180200-66-2 ≥98% 402.42 C19H22FN3O4  3/2H2O CC1CN(CCN1)C2=C(C=C3C(=C2OC)N(C=C(C3=O)C(=O)O)C4CC4)F Ambient Ambient Soluble in water (40-60 mg/mL) at a pH of 2 to 5. "Pantel A, Petrella S, Veziris N, et al. Extending the definition of the GyrB quinolone resistance-determining region in Mycobacterium tuberculosis DNA gyrase for assessing fluoroquinolone resistance in M. tuberculosis. Antimicrob Agents Chemother. 2012 Apr;56(4):1990-6. PMID: 22290942.

 

Croisier D, Etienne M, Piroth L, et al. In vivo pharmacodynamic efficacy of gatifloxacin against Streptococcus pneumoniae in an experimental model of pneumonia: impact of the low levels of fluoroquinolone resistance on the enrichment of resistant mutants. J Antimicrob Chemother. 2004 Sep;54(3):640-7. PMID: 15317743.

" Xn Not dangerous goods.

LKT G0278 Gatifloxacin Sesquihydrate 5 g 285.4 Fluoroquinolone; bacterial DNA gyrase inhibitor. 1-Cyclopropyl-6-fluoro-1,4-dihydro-8-methoxy-7-(3-methyl-1-piperazinyl)-4-oxo-3-quinolinecarboxylic acid Tequin 180200-66-2 ≥98% 402.42 C19H22FN3O4  3/2H2O CC1CN(CCN1)C2=C(C=C3C(=C2OC)N(C=C(C3=O)C(=O)O)C4CC4)F Ambient Ambient Soluble in water (40-60 mg/mL) at a pH of 2 to 5. "Pantel A, Petrella S, Veziris N, et al. Extending the definition of the GyrB quinolone resistance-determining region in Mycobacterium tuberculosis DNA gyrase for assessing fluoroquinolone resistance in M. tuberculosis. Antimicrob Agents Chemother. 2012 Apr;56(4):1990-6. PMID: 22290942.

 

Croisier D, Etienne M, Piroth L, et al. In vivo pharmacodynamic efficacy of gatifloxacin against Streptococcus pneumoniae in an experimental model of pneumonia: impact of the low levels of fluoroquinolone resistance on the enrichment of resistant mutants. J Antimicrob Chemother. 2004 Sep;54(3):640-7. PMID: 15317743.

" Xn Not dangerous goods.

LKT E6234 Epigallocatechin Gallate 25 mg 51.8 Flavanol found in Camilla (green tea);  AhR antagonist, STAT3, α-amylase, α-glucosidase inhibitor. 3,4,5-Trihydroxybenzoic acid, (2R,3R)-3,4-dihydro- 5,7-dihydroxy-2-(3,4,5-trihydroxyphenyl)-2H-1- benzopyran-3-yl (-)-Epigallocatechin gallate; EGCG; 3-O-gallate 989-51-5 ≥98% 458.37 C22H18O11 C1C(C(OC2=CC(=CC(=C21)O)O)C3=CC(=C(C(=C3)O)O)O)OC(=O)C4=CC(=C(C(=C4)O)O)O Ambient 4°C Soluble in methanol, ethnol (92mg/mL) or DMSO (92mg/mL). Slightly soluble in water. "Moses MA, Henry EC, Ricke WA, et al. The heat shock protein 90 inhibitor, (-)-epigallocatechin gallate, has anticancer activity in a novel human prostate cancer progression model. Cancer Prev Res (Phila). 2015 Mar;8(3):249-57. PMID: 25604133.

 

Lorenzen N, Nielsen SB, Yoshimura Y, et al. How epigallocatechin gallate can inhibit α-synuclein oligomer toxicity in vitro. J Biol Chem. 2014 Aug 1;289(31):21299-310. PMID: 24907278.

 

Bao S, Cao Y, Fan C, et al. Epigallocatechin gallate improves insulin signaling by decreasing toll-like receptor 4 (TLR4) activity in adipose tissues of high-fat diet rats. Mol Nutr Food Res. 2014 Apr;58(4):677-86. PMID: 24259392 

 

Shen X, Zhang Y, Feng Y, et al. Epigallocatechin-3-gallate inhibits cell growth, induces apoptosis and causes S phase arrest in hepatocellular carcinoma by suppressing the AKT pathway. Int J Oncol. 2014 Mar;44(3):791-6. PMID: 24402647.

 

da Silva CR, de Andrade Neto JB, de Sousa Campos R, et al. Synergistic effect of the flavonoid catechin, quercetin, or epigallocatechin gallate with fluconazole induces apoptosis in Candida tropicalis resistant to fluconazole. Antimicrob Agents Chemother. 2014;58(3):1468-78. PMID: 24366745.

 

Ma YC, Li C, Gao F, et al. Epigallocatechin gallate inhibits the growth of human lung cancer by directly targeting the EGFR signaling pathway. Oncol Rep. 2014 Mar;31(3):1343-9. PMID: 24366444.

 

Saito K, Mori S, Date F, et al. Epigallocatechin gallate inhibits oxidative stress-induced DNA damage and apoptosis in MRL-Fas(lpr) mice with autoimmune sialadenitis via upregulation of heme oxygenase-1 and Bcl-2. Autoimmunity. 2014 Feb;47(1):13-22. PMID: 24392721.

 

Takahashi A, Watanabe T, Mondal A, et al. Mechanism-based inhibition of cancer metastasis with (-)-epigallocatechin gallate. Biochem Biophys Res Commun. 2014 Jan 3;443(1):1-6. PMID: 24269590.

 

Jankun J, Keck RW, Selman SH. Epigallocatechin-3-gallate prevents tumor cell implantation/growth in an experimental rat bladder tumor model. Int J Oncol. 2014 Jan;44(1):147-52. PMID: 24220494.

 

Wang Y, Ren X, Deng C, et al. Mechanism of the inhibition of the STAT3 signaling pathway by EGCG. Oncol Rep. 2013 Dec;30(6):2691-6. PMID: 24065300.

 

Bleiholder C, Do TD, Wu C, et al. Ion mobility spectrometry reveals the mechanism of amyloid formation of Aβ(25-35) and its modulation by inhibitors at the molecular level: epigallocatechin gallate and scyllo-inositol. J Am Chem Soc. 2013 Nov 13;135(45):16926-37. PMID: 24131107.

 

Gao J, Xu P, Wang Y, et al. Combined effects of green tea extracts, green tea polyphenols or epigallocatechin gallate with acarbose on inhibition against α-amylase and α-glucosidase in vitro. Molecules. 2013 Sep 18;18(9):11614-23. PMID: 24051476.

 

Yu J, Jia Y, Guo Y, et al. Epigallocatechin-3-gallate protects motor neurons and regulates glutamate level. FEBS Lett. 2010 Jul 2;584(13):2921-2925. PMID: 20488180.

" Xi Not dangerous goods.

LKT E6234 Epigallocatechin Gallate 50 mg 85.3 Flavanol found in Camilla (green tea);  AhR antagonist, STAT3, α-amylase, α-glucosidase inhibitor. 3,4,5-Trihydroxybenzoic acid, (2R,3R)-3,4-dihydro- 5,7-dihydroxy-2-(3,4,5-trihydroxyphenyl)-2H-1- benzopyran-3-yl (-)-Epigallocatechin gallate; EGCG; 3-O-gallate 989-51-5 ≥98% 458.37 C22H18O11 C1C(C(OC2=CC(=CC(=C21)O)O)C3=CC(=C(C(=C3)O)O)O)OC(=O)C4=CC(=C(C(=C4)O)O)O Ambient 4°C Soluble in methanol, ethnol (92mg/mL) or DMSO (92mg/mL). Slightly soluble in water. "Moses MA, Henry EC, Ricke WA, et al. The heat shock protein 90 inhibitor, (-)-epigallocatechin gallate, has anticancer activity in a novel human prostate cancer progression model. Cancer Prev Res (Phila). 2015 Mar;8(3):249-57. PMID: 25604133.

 

Lorenzen N, Nielsen SB, Yoshimura Y, et al. How epigallocatechin gallate can inhibit α-synuclein oligomer toxicity in vitro. J Biol Chem. 2014 Aug 1;289(31):21299-310. PMID: 24907278.

 

Bao S, Cao Y, Fan C, et al. Epigallocatechin gallate improves insulin signaling by decreasing toll-like receptor 4 (TLR4) activity in adipose tissues of high-fat diet rats. Mol Nutr Food Res. 2014 Apr;58(4):677-86. PMID: 24259392 

 

Shen X, Zhang Y, Feng Y, et al. Epigallocatechin-3-gallate inhibits cell growth, induces apoptosis and causes S phase arrest in hepatocellular carcinoma by suppressing the AKT pathway. Int J Oncol. 2014 Mar;44(3):791-6. PMID: 24402647.

 

da Silva CR, de Andrade Neto JB, de Sousa Campos R, et al. Synergistic effect of the flavonoid catechin, quercetin, or epigallocatechin gallate with fluconazole induces apoptosis in Candida tropicalis resistant to fluconazole. Antimicrob Agents Chemother. 2014;58(3):1468-78. PMID: 24366745.

 

Ma YC, Li C, Gao F, et al. Epigallocatechin gallate inhibits the growth of human lung cancer by directly targeting the EGFR signaling pathway. Oncol Rep. 2014 Mar;31(3):1343-9. PMID: 24366444.

 

Saito K, Mori S, Date F, et al. Epigallocatechin gallate inhibits oxidative stress-induced DNA damage and apoptosis in MRL-Fas(lpr) mice with autoimmune sialadenitis via upregulation of heme oxygenase-1 and Bcl-2. Autoimmunity. 2014 Feb;47(1):13-22. PMID: 24392721.

 

Takahashi A, Watanabe T, Mondal A, et al. Mechanism-based inhibition of cancer metastasis with (-)-epigallocatechin gallate. Biochem Biophys Res Commun. 2014 Jan 3;443(1):1-6. PMID: 24269590.

 

Jankun J, Keck RW, Selman SH. Epigallocatechin-3-gallate prevents tumor cell implantation/growth in an experimental rat bladder tumor model. Int J Oncol. 2014 Jan;44(1):147-52. PMID: 24220494.

 

Wang Y, Ren X, Deng C, et al. Mechanism of the inhibition of the STAT3 signaling pathway by EGCG. Oncol Rep. 2013 Dec;30(6):2691-6. PMID: 24065300.

 

Bleiholder C, Do TD, Wu C, et al. Ion mobility spectrometry reveals the mechanism of amyloid formation of Aβ(25-35) and its modulation by inhibitors at the molecular level: epigallocatechin gallate and scyllo-inositol. J Am Chem Soc. 2013 Nov 13;135(45):16926-37. PMID: 24131107.

 

Gao J, Xu P, Wang Y, et al. Combined effects of green tea extracts, green tea polyphenols or epigallocatechin gallate with acarbose on inhibition against α-amylase and α-glucosidase in vitro. Molecules. 2013 Sep 18;18(9):11614-23. PMID: 24051476.

 

Yu J, Jia Y, Guo Y, et al. Epigallocatechin-3-gallate protects motor neurons and regulates glutamate level. FEBS Lett. 2010 Jul 2;584(13):2921-2925. PMID: 20488180.

" Xi Not dangerous goods.

LKT E6234 Epigallocatechin Gallate 100 mg 149.9 Flavanol found in Camilla (green tea);  AhR antagonist, STAT3, α-amylase, α-glucosidase inhibitor. 3,4,5-Trihydroxybenzoic acid, (2R,3R)-3,4-dihydro- 5,7-dihydroxy-2-(3,4,5-trihydroxyphenyl)-2H-1- benzopyran-3-yl (-)-Epigallocatechin gallate; EGCG; 3-O-gallate 989-51-5 ≥98% 458.37 C22H18O11 C1C(C(OC2=CC(=CC(=C21)O)O)C3=CC(=C(C(=C3)O)O)O)OC(=O)C4=CC(=C(C(=C4)O)O)O Ambient 4°C Soluble in methanol, ethnol (92mg/mL) or DMSO (92mg/mL). Slightly soluble in water. "Moses MA, Henry EC, Ricke WA, et al. The heat shock protein 90 inhibitor, (-)-epigallocatechin gallate, has anticancer activity in a novel human prostate cancer progression model. Cancer Prev Res (Phila). 2015 Mar;8(3):249-57. PMID: 25604133.

 

Lorenzen N, Nielsen SB, Yoshimura Y, et al. How epigallocatechin gallate can inhibit α-synuclein oligomer toxicity in vitro. J Biol Chem. 2014 Aug 1;289(31):21299-310. PMID: 24907278.

 

Bao S, Cao Y, Fan C, et al. Epigallocatechin gallate improves insulin signaling by decreasing toll-like receptor 4 (TLR4) activity in adipose tissues of high-fat diet rats. Mol Nutr Food Res. 2014 Apr;58(4):677-86. PMID: 24259392 

 

Shen X, Zhang Y, Feng Y, et al. Epigallocatechin-3-gallate inhibits cell growth, induces apoptosis and causes S phase arrest in hepatocellular carcinoma by suppressing the AKT pathway. Int J Oncol. 2014 Mar;44(3):791-6. PMID: 24402647.

 

da Silva CR, de Andrade Neto JB, de Sousa Campos R, et al. Synergistic effect of the flavonoid catechin, quercetin, or epigallocatechin gallate with fluconazole induces apoptosis in Candida tropicalis resistant to fluconazole. Antimicrob Agents Chemother. 2014;58(3):1468-78. PMID: 24366745.

 

Ma YC, Li C, Gao F, et al. Epigallocatechin gallate inhibits the growth of human lung cancer by directly targeting the EGFR signaling pathway. Oncol Rep. 2014 Mar;31(3):1343-9. PMID: 24366444.

 

Saito K, Mori S, Date F, et al. Epigallocatechin gallate inhibits oxidative stress-induced DNA damage and apoptosis in MRL-Fas(lpr) mice with autoimmune sialadenitis via upregulation of heme oxygenase-1 and Bcl-2. Autoimmunity. 2014 Feb;47(1):13-22. PMID: 24392721.

 

Takahashi A, Watanabe T, Mondal A, et al. Mechanism-based inhibition of cancer metastasis with (-)-epigallocatechin gallate. Biochem Biophys Res Commun. 2014 Jan 3;443(1):1-6. PMID: 24269590.

 

Jankun J, Keck RW, Selman SH. Epigallocatechin-3-gallate prevents tumor cell implantation/growth in an experimental rat bladder tumor model. Int J Oncol. 2014 Jan;44(1):147-52. PMID: 24220494.

 

Wang Y, Ren X, Deng C, et al. Mechanism of the inhibition of the STAT3 signaling pathway by EGCG. Oncol Rep. 2013 Dec;30(6):2691-6. PMID: 24065300.

 

Bleiholder C, Do TD, Wu C, et al. Ion mobility spectrometry reveals the mechanism of amyloid formation of Aβ(25-35) and its modulation by inhibitors at the molecular level: epigallocatechin gallate and scyllo-inositol. J Am Chem Soc. 2013 Nov 13;135(45):16926-37. PMID: 24131107.

 

Gao J, Xu P, Wang Y, et al. Combined effects of green tea extracts, green tea polyphenols or epigallocatechin gallate with acarbose on inhibition against α-amylase and α-glucosidase in vitro. Molecules. 2013 Sep 18;18(9):11614-23. PMID: 24051476.

 

Yu J, Jia Y, Guo Y, et al. Epigallocatechin-3-gallate protects motor neurons and regulates glutamate level. FEBS Lett. 2010 Jul 2;584(13):2921-2925. PMID: 20488180.

" Xi Not dangerous goods.

LKT I4802 Imatinib Mesylate 25 mg 48.8 Abl, c-Kit, PDGFR inhibitor. methanesulfonic acid; 4-[(4-methylpiperazin-1-yl)methyl]-N-[4-methyl-3-[(4-pyridin-3-ylpyrimidin-2-yl)amino]phenyl]benzamide 220127-57-1 ≥98% 589.718 C30H35N7O4S CC1=C(C=C(C=C1)NC(=O)C2=CC=C(C=C2)CN3CCN(CC3)C)NC4=NC=CC(=N4)C5=CN=CC=C5.CS(=O)(=O)O In DMSO at +4 for 2 weeks at -80 for 6 months Ambient Ambient Ethanol (0.2 mg/ml), DMSO (10 mg/ml), Dimethyl Formamide, PBS (2 mg/mL) "Wang Y, Zhao Y, Liu L, et al. Inhibitory effects of imatinib mesylate on human epidermal melanocytes. Clin Exp Dermatol. 2014 Mar;39(2):202-8. PMID: 24479586.

 

D'allard D, Gay J, Descarpentries C, et al. Tyrosine kinase inhibitors induce down-regulation of c-Kit by targeting the ATP pocket. PLoS One. 2013 Apr 23;8(4):e60961. PMID: 23637779.

 

Gambacorti-Passerini CB, Gunby RH, Piazza R, et al. Molecular mechanisms of resistance to imatinib in Philadelphia-chromosome-positive leukaemias. Lancet Oncol. 2003 Feb;4(2):75-85. PMID: 12573349.

" Not dangerous goods.

LKT I4802 Imatinib Mesylate 100 mg 133.2 Abl, c-Kit, PDGFR inhibitor. methanesulfonic acid; 4-[(4-methylpiperazin-1-yl)methyl]-N-[4-methyl-3-[(4-pyridin-3-ylpyrimidin-2-yl)amino]phenyl]benzamide 220127-57-1 ≥98% 589.718 C30H35N7O4S CC1=C(C=C(C=C1)NC(=O)C2=CC=C(C=C2)CN3CCN(CC3)C)NC4=NC=CC(=N4)C5=CN=CC=C5.CS(=O)(=O)O In DMSO at +4 for 2 weeks at -80 for 6 months Ambient Ambient Ethanol (0.2 mg/ml), DMSO (10 mg/ml), Dimethyl Formamide, PBS (2 mg/mL) "Wang Y, Zhao Y, Liu L, et al. Inhibitory effects of imatinib mesylate on human epidermal melanocytes. Clin Exp Dermatol. 2014 Mar;39(2):202-8. PMID: 24479586.

 

D'allard D, Gay J, Descarpentries C, et al. Tyrosine kinase inhibitors induce down-regulation of c-Kit by targeting the ATP pocket. PLoS One. 2013 Apr 23;8(4):e60961. PMID: 23637779.

 

Gambacorti-Passerini CB, Gunby RH, Piazza R, et al. Molecular mechanisms of resistance to imatinib in Philadelphia-chromosome-positive leukaemias. Lancet Oncol. 2003 Feb;4(2):75-85. PMID: 12573349.

" Not dangerous goods.

LKT I4802 Imatinib Mesylate 500 mg 407.7 Abl, c-Kit, PDGFR inhibitor. methanesulfonic acid; 4-[(4-methylpiperazin-1-yl)methyl]-N-[4-methyl-3-[(4-pyridin-3-ylpyrimidin-2-yl)amino]phenyl]benzamide 220127-57-1 ≥98% 589.718 C30H35N7O4S CC1=C(C=C(C=C1)NC(=O)C2=CC=C(C=C2)CN3CCN(CC3)C)NC4=NC=CC(=N4)C5=CN=CC=C5.CS(=O)(=O)O In DMSO at +4 for 2 weeks at -80 for 6 months Ambient Ambient Ethanol (0.2 mg/ml), DMSO (10 mg/ml), Dimethyl Formamide, PBS (2 mg/mL) "Wang Y, Zhao Y, Liu L, et al. Inhibitory effects of imatinib mesylate on human epidermal melanocytes. Clin Exp Dermatol. 2014 Mar;39(2):202-8. PMID: 24479586.

 

D'allard D, Gay J, Descarpentries C, et al. Tyrosine kinase inhibitors induce down-regulation of c-Kit by targeting the ATP pocket. PLoS One. 2013 Apr 23;8(4):e60961. PMID: 23637779.

 

Gambacorti-Passerini CB, Gunby RH, Piazza R, et al. Molecular mechanisms of resistance to imatinib in Philadelphia-chromosome-positive leukaemias. Lancet Oncol. 2003 Feb;4(2):75-85. PMID: 12573349.

" Not dangerous goods.

LKT C9709 Cycloheximide 1 g 67.9 Protein synthesis inhibitor, used to measure protein lifespan. [1S-[1αS*),3α,5β]]-4-[2-(3,5-Dimethyl-2-oxocyclo- hexyl)-2-hydroxyethyl]-2,6-piperidinedione Naramycin A; Actidione 66-81-9 ≥95% 281.35 C15H23NO4 CC1CC(C(=O)C(C1)C(CC2CC(=O)NC(=O)C2)O)C "Cycloheximide has been reported to be soluble up to 2% (w/v) in water (20 mg/ml).14 The powder will dissolve slowly in water and this process may be aided by mixing or sonication. More dilute solutions (5 mg/ml) may be prepared without sonication. Aqueous solution stability is pH dependent. Solutions are stable for several weeks in the pH range of 3 to 5, which is the range optimal for stability. For longer term solution storage, refrigeration is suggested. Solutions refrigerated over 18 months, retained 75% of the original activity.13 Solutions prepared in distilled water may be sterile filtered or autoclaved without serious loss of activity.13 Autoclaving of medium containing cycloheximide is not recommended. The sterile cycloheximide solution should be added to sterile broth or cooled, sterile, melted agar.13 Boiling for one hour at pH 7 destroys activity, but no loss of activity is observed after 15 minutes. Under acidic conditions (pH 2), activity is not destroyed after one hour of boiling.14 Under

dilute alkali conditions, decomposition occurs rapidly in solution at room temperature with the formation of 2,4-dimethylcyclohexanone. 14

Cycloheximide is also soluble in most organic solvents, including ethanol, with the exception of saturated hydrocarbons.14" Ambient 4°C Soluble in chloroform, DMSO, acetone, methanol, or ethanol. Soluble in water to 20 mg/ml. "Bohnert M, Scherer O, Wiechmann K, et al. Melleolides induce rapid cell death in human primary monocytes and cancer cells. Bioorg Med Chem. 2014 Aug 1;22(15):3856-61. PMID: 25028062.

 

Ren Y, D'Ambrosio MA, Garvin JL, et al. Aldosterone sensitizes connecting tubule glomerular feedback via the aldosterone receptor GPR30. Am J Physiol Renal Physiol. 2014 Aug 15;307(4):F427-34. PMID: 24966088.

 

Greenberger NJ, Ruppert RD. Inhibition of protein synthesis: a mechanism for the production of impaired iron absorption. Science. 1966 Jul 15;153(3733):315-6. PMID: 17780009.

" Xn, T+, Repr., N, Mut. "UN number: 2811     Class:  6.1     Packing group:  I

Proper shipping name:  Toxic solids, organic, n.o.s. (Cycloheximide)

Reportable Quantity (RQ):      

Poison inhalation hazard:  No"

LKT C9709 Cycloheximide 5 g 197.1 Protein synthesis inhibitor, used to measure protein lifespan. [1S-[1αS*),3α,5β]]-4-[2-(3,5-Dimethyl-2-oxocyclo- hexyl)-2-hydroxyethyl]-2,6-piperidinedione Naramycin A; Actidione 66-81-9 ≥95% 281.35 C15H23NO4 CC1CC(C(=O)C(C1)C(CC2CC(=O)NC(=O)C2)O)C "Cycloheximide has been reported to be soluble up to 2% (w/v) in water (20 mg/ml).14 The powder will dissolve slowly in water and this process may be aided by mixing or sonication. More dilute solutions (5 mg/ml) may be prepared without sonication. Aqueous solution stability is pH dependent. Solutions are stable for several weeks in the pH range of 3 to 5, which is the range optimal for stability. For longer term solution storage, refrigeration is suggested. Solutions refrigerated over 18 months, retained 75% of the original activity.13 Solutions prepared in distilled water may be sterile filtered or autoclaved without serious loss of activity.13 Autoclaving of medium containing cycloheximide is not recommended. The sterile cycloheximide solution should be added to sterile broth or cooled, sterile, melted agar.13 Boiling for one hour at pH 7 destroys activity, but no loss of activity is observed after 15 minutes. Under acidic conditions (pH 2), activity is not destroyed after one hour of boiling.14 Under

dilute alkali conditions, decomposition occurs rapidly in solution at room temperature with the formation of 2,4-dimethylcyclohexanone. 14

Cycloheximide is also soluble in most organic solvents, including ethanol, with the exception of saturated hydrocarbons.14" Ambient 4°C Soluble in chloroform, DMSO, acetone, methanol, or ethanol. Soluble in water to 20 mg/ml. "Bohnert M, Scherer O, Wiechmann K, et al. Melleolides induce rapid cell death in human primary monocytes and cancer cells. Bioorg Med Chem. 2014 Aug 1;22(15):3856-61. PMID: 25028062.

 

Ren Y, D'Ambrosio MA, Garvin JL, et al. Aldosterone sensitizes connecting tubule glomerular feedback via the aldosterone receptor GPR30. Am J Physiol Renal Physiol. 2014 Aug 15;307(4):F427-34. PMID: 24966088.

 

Greenberger NJ, Ruppert RD. Inhibition of protein synthesis: a mechanism for the production of impaired iron absorption. Science. 1966 Jul 15;153(3733):315-6. PMID: 17780009.

" Xn, T+, Repr., N, Mut. "UN number: 2811     Class:  6.1     Packing group:  I

Proper shipping name:  Toxic solids, organic, n.o.s. (Cycloheximide)

Reportable Quantity (RQ):      

Poison inhalation hazard:  No"

LKT B8271 Bursin 5 mg 60 Tripeptide, adjuvant, induces B-cell differentiation. Bursopoietin; Lys-his-gly-NH2 60267-34-7 ≥95% 339.39 C14H25N7O3 C1=NC=NC1CC(C(=O)NCC(=O)N)NC(=O)C(CCCCN)N Ambient -20°C "Wang C, Wen WY, Su CX, et al. Bursin as an adjuvant is a potent enhancer of immune response in mice immunized with the JEV subunit vaccine. Vet Immunol Immunopathol. 2008 Apr 15;122(3-4):265-74. PMID: 18191231.

 

Otsubo Y, Chen N, Kajiwara E, et al. Role of bursin in the development of B lymphocytes in chicken embryonic Bursa of Fabricius. Dev Comp Immunol. 2001 Jun-Jul;25(5-6):485-93. PMID: 11356228.

"

LKT B8271 Bursin 10 mg 101.9 Tripeptide, adjuvant, induces B-cell differentiation. Bursopoietin; Lys-his-gly-NH2 60267-34-7 ≥95% 339.39 C14H25N7O3 C1=NC=NC1CC(C(=O)NCC(=O)N)NC(=O)C(CCCCN)N Ambient -20°C "Wang C, Wen WY, Su CX, et al. Bursin as an adjuvant is a potent enhancer of immune response in mice immunized with the JEV subunit vaccine. Vet Immunol Immunopathol. 2008 Apr 15;122(3-4):265-74. PMID: 18191231.

 

Otsubo Y, Chen N, Kajiwara E, et al. Role of bursin in the development of B lymphocytes in chicken embryonic Bursa of Fabricius. Dev Comp Immunol. 2001 Jun-Jul;25(5-6):485-93. PMID: 11356228.

"

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