LKT Labs L1884 Levosimendan sensitizer

LKT Labs 是一家专注于防癌抗癌特殊化学品研究和开发的公司。主要提供：癌症药物、药物发现试剂盒、天然产物、广泛的生命科学研究试剂、定制合成。
美国LKT Labs 是1988年在美国成立的，为全球提供先端的药物研发试剂、试剂盒、委托合成，并为药物生产企业提供原料，最近几年在农药、水产养殖业有很大程度的开发。在LKT Labs 可以找到在其他地方找不到的产品。

LKT Labs L1884 Levosimendan sensitizer

LKT Labs L1884 Levosimendan sensitizer

LKT T3039 Thienyloctyl Isothiocyanate 25 mg 216.3 Thienylbutyl ITC analog. ≥98% 253.43 C13H19NS2 Ambient 4°C Munday R, Zhang Y, Munday CM, et al. Structure-activity relationships and organ specificity in the induction of GST and NQO1 by alkyl-aryl isothiocyanates. Pharm Res. 2008 Sep;25(9):2164-70. PMID: 18563540. Not dangerous goods.

LKT T3039 Thienyloctyl Isothiocyanate 50 mg 336 Thienylbutyl ITC analog. ≥98% 253.43 C13H19NS2 Ambient 4°C Munday R, Zhang Y, Munday CM, et al. Structure-activity relationships and organ specificity in the induction of GST and NQO1 by alkyl-aryl isothiocyanates. Pharm Res. 2008 Sep;25(9):2164-70. PMID: 18563540. Not dangerous goods.

LKT T3039 Thienyloctyl Isothiocyanate 100 mg 545.7 Thienylbutyl ITC analog. ≥98% 253.43 C13H19NS2 Ambient 4°C Munday R, Zhang Y, Munday CM, et al. Structure-activity relationships and organ specificity in the induction of GST and NQO1 by alkyl-aryl isothiocyanates. Pharm Res. 2008 Sep;25(9):2164-70. PMID: 18563540. Not dangerous goods.

LKT H9712 (E)-4-Hydroxytamoxifen 5 mg 149.6 SERM. 174592-47-3 ≥97% 387.51 C26H29NO2 CCC(=C(C1=CC=C(C=C1)O)C2=CC=C(C=C2)OCCN(C)C)C3=CC=CC=C3 Ambient -20°C "Asp ML, Martindale JJ, Metzger JM. Direct, differential effects of tamoxifen, 4-hydroxytamoxifen, and raloxifene on cardiac myocyte contractility and calcium handling. PLoS One. 2013 Oct 24;8(10):e78768. PMID: 24205315.

Kohli L, Kaza N, Coric T, et al. 4-Hydroxytamoxifen induces autophagic death through K-Ras degradation. Cancer Res. 2013 Jul 15;73(14):4395-405. PMID: 23722551.

Schwartz JA, Zhong L, Deighton-Collins S, et al. Mutations targeted to a predicted helix in the extreme carboxyl-terminal region of the human estrogen receptor-alpha alter its response to estradiol and 4-hydroxytamoxifen. J Biol Chem. 2002 Apr 12;277(15):13202-9. Erratum in: J Biol Chem 2002 Jul 5;277(27):24842.  PMID: 11823467.

" Not dangerous goods.

LKT T3039 Thienyloctyl Isothiocyanate 500 mg 2173.1 Thienylbutyl ITC analog. ≥98% 253.43 C13H19NS2 Ambient 4°C Munday R, Zhang Y, Munday CM, et al. Structure-activity relationships and organ specificity in the induction of GST and NQO1 by alkyl-aryl isothiocyanates. Pharm Res. 2008 Sep;25(9):2164-70. PMID: 18563540. Not dangerous goods.

LKT H9712 (E)-4-Hydroxytamoxifen 10 mg 249.4 SERM. 174592-47-3 ≥97% 387.51 C26H29NO2 CCC(=C(C1=CC=C(C=C1)O)C2=CC=C(C=C2)OCCN(C)C)C3=CC=CC=C3 Ambient -20°C "Asp ML, Martindale JJ, Metzger JM. Direct, differential effects of tamoxifen, 4-hydroxytamoxifen, and raloxifene on cardiac myocyte contractility and calcium handling. PLoS One. 2013 Oct 24;8(10):e78768. PMID: 24205315.

Kohli L, Kaza N, Coric T, et al. 4-Hydroxytamoxifen induces autophagic death through K-Ras degradation. Cancer Res. 2013 Jul 15;73(14):4395-405. PMID: 23722551.

Schwartz JA, Zhong L, Deighton-Collins S, et al. Mutations targeted to a predicted helix in the extreme carboxyl-terminal region of the human estrogen receptor-alpha alter its response to estradiol and 4-hydroxytamoxifen. J Biol Chem. 2002 Apr 12;277(15):13202-9. Erratum in: J Biol Chem 2002 Jul 5;277(27):24842.  PMID: 11823467.

" Not dangerous goods.

LKT H9712 (E)-4-Hydroxytamoxifen 25 mg 519.8 SERM. 174592-47-3 ≥97% 387.51 C26H29NO2 CCC(=C(C1=CC=C(C=C1)O)C2=CC=C(C=C2)OCCN(C)C)C3=CC=CC=C3 Ambient -20°C "Asp ML, Martindale JJ, Metzger JM. Direct, differential effects of tamoxifen, 4-hydroxytamoxifen, and raloxifene on cardiac myocyte contractility and calcium handling. PLoS One. 2013 Oct 24;8(10):e78768. PMID: 24205315.

Kohli L, Kaza N, Coric T, et al. 4-Hydroxytamoxifen induces autophagic death through K-Ras degradation. Cancer Res. 2013 Jul 15;73(14):4395-405. PMID: 23722551.

Schwartz JA, Zhong L, Deighton-Collins S, et al. Mutations targeted to a predicted helix in the extreme carboxyl-terminal region of the human estrogen receptor-alpha alter its response to estradiol and 4-hydroxytamoxifen. J Biol Chem. 2002 Apr 12;277(15):13202-9. Erratum in: J Biol Chem 2002 Jul 5;277(27):24842.  PMID: 11823467.

" Not dangerous goods.

LKT T3038 Thienylnonanyl Isothiocyanate 25 mg 246.4 Thienylbutyl ITC analog. ≥98% 267.46 C14H21NS2 Ambient 4°C "Lam LKT, Kenney P, Bergstrom CP, et al.  Chem Biol Interact. 1999;127:163-80.

Hecht SS. Chemoprevention by isothiocyanates. J Cell Biochem Suppl. 1995;22:195-209. PMID: 8538199." Not dangerous goods.

LKT H9714 L-5-Hydroxytryptophan 250 mg 30.7 Endogenous amino acid, precursor of 5-HT and melatonin. L-5HTP; Oxitriptan; Cincofarm; Levothym; Oxyfann; Telestol 4350-09-8 ≥98% 220.22 C11H12N2O3 C1=CC2=C(C=C1O)C(=CN2)CC(C(=O)O)N Ambient Ambient Slightly soluble in water. "Jangid P, Malik P, Singh P, et al. Comparative study of efficacy of l-5-hydroxytryptophan and fluoxetine in patients presenting with first depressive episode. Asian J Psychiatr. 2013 Feb;6(1):29-34. PMID: 23380314.

Basu P, Singaravel M, Haldar C. L-5-hydroxytryptophan resets the circadian locomotor activity rhythm of the nocturnal Indian pygmy field mouse, Mus terricolor. Naturwissenschaften. 2012 Mar;99(3):233-9. PMID: 22331255.

Lysek N, Kinscherf R, Claus R, et al. L-5-Hydroxytryptophan: antioxidant and anti-apoptotic principle of the intertidal sponge Hymeniacidon heliophila. Z Naturforsch C. 2003 Jul-Aug;58(7-8):568-72. PMID: 12939046.

" Xn "UN number: 2811     Class: 6.1     Packing Group: III

Proper shipping name: Toxic solid, organic, n.o.s. (L-5-Hydroxytryptophan)"

LKT H9714 L-5-Hydroxytryptophan 1 g 51.1 Endogenous amino acid, precursor of 5-HT and melatonin. L-5HTP; Oxitriptan; Cincofarm; Levothym; Oxyfann; Telestol 4350-09-8 ≥98% 220.22 C11H12N2O3 C1=CC2=C(C=C1O)C(=CN2)CC(C(=O)O)N Ambient Ambient Slightly soluble in water. "Jangid P, Malik P, Singh P, et al. Comparative study of efficacy of l-5-hydroxytryptophan and fluoxetine in patients presenting with first depressive episode. Asian J Psychiatr. 2013 Feb;6(1):29-34. PMID: 23380314.

Basu P, Singaravel M, Haldar C. L-5-hydroxytryptophan resets the circadian locomotor activity rhythm of the nocturnal Indian pygmy field mouse, Mus terricolor. Naturwissenschaften. 2012 Mar;99(3):233-9. PMID: 22331255.

Lysek N, Kinscherf R, Claus R, et al. L-5-Hydroxytryptophan: antioxidant and anti-apoptotic principle of the intertidal sponge Hymeniacidon heliophila. Z Naturforsch C. 2003 Jul-Aug;58(7-8):568-72. PMID: 12939046.

" Xn "UN number: 2811     Class: 6.1     Packing Group: III

Proper shipping name: Toxic solid, organic, n.o.s. (L-5-Hydroxytryptophan)"

LKT T3038 Thienylnonanyl Isothiocyanate 50 mg 442.3 Thienylbutyl ITC analog. ≥98% 267.46 C14H21NS2 Ambient 4°C "Lam LKT, Kenney P, Bergstrom CP, et al.  Chem Biol Interact. 1999;127:163-80.

Hecht SS. Chemoprevention by isothiocyanates. J Cell Biochem Suppl. 1995;22:195-209. PMID: 8538199." Not dangerous goods.

LKT H9714 L-5-Hydroxytryptophan 5 g 140 Endogenous amino acid, precursor of 5-HT and melatonin. L-5HTP; Oxitriptan; Cincofarm; Levothym; Oxyfann; Telestol 4350-09-8 ≥98% 220.22 C11H12N2O3 C1=CC2=C(C=C1O)C(=CN2)CC(C(=O)O)N Ambient Ambient Slightly soluble in water. "Jangid P, Malik P, Singh P, et al. Comparative study of efficacy of l-5-hydroxytryptophan and fluoxetine in patients presenting with first depressive episode. Asian J Psychiatr. 2013 Feb;6(1):29-34. PMID: 23380314.

Basu P, Singaravel M, Haldar C. L-5-hydroxytryptophan resets the circadian locomotor activity rhythm of the nocturnal Indian pygmy field mouse, Mus terricolor. Naturwissenschaften. 2012 Mar;99(3):233-9. PMID: 22331255.

Lysek N, Kinscherf R, Claus R, et al. L-5-Hydroxytryptophan: antioxidant and anti-apoptotic principle of the intertidal sponge Hymeniacidon heliophila. Z Naturforsch C. 2003 Jul-Aug;58(7-8):568-72. PMID: 12939046.

" Xn "UN number: 2811     Class: 6.1     Packing Group: III

Proper shipping name: Toxic solid, organic, n.o.s. (L-5-Hydroxytryptophan)"

LKT H9714 L-5-Hydroxytryptophan 25 g 533.8 Endogenous amino acid, precursor of 5-HT and melatonin. L-5HTP; Oxitriptan; Cincofarm; Levothym; Oxyfann; Telestol 4350-09-8 ≥98% 220.22 C11H12N2O3 C1=CC2=C(C=C1O)C(=CN2)CC(C(=O)O)N Ambient Ambient Slightly soluble in water. "Jangid P, Malik P, Singh P, et al. Comparative study of efficacy of l-5-hydroxytryptophan and fluoxetine in patients presenting with first depressive episode. Asian J Psychiatr. 2013 Feb;6(1):29-34. PMID: 23380314.

Basu P, Singaravel M, Haldar C. L-5-hydroxytryptophan resets the circadian locomotor activity rhythm of the nocturnal Indian pygmy field mouse, Mus terricolor. Naturwissenschaften. 2012 Mar;99(3):233-9. PMID: 22331255.

Lysek N, Kinscherf R, Claus R, et al. L-5-Hydroxytryptophan: antioxidant and anti-apoptotic principle of the intertidal sponge Hymeniacidon heliophila. Z Naturforsch C. 2003 Jul-Aug;58(7-8):568-72. PMID: 12939046.

" Xn "UN number: 2811     Class: 6.1     Packing Group: III

Proper shipping name: Toxic solid, organic, n.o.s. (L-5-Hydroxytryptophan)"

LKT T3038 Thienylnonanyl Isothiocyanate 100 mg 791.9 Thienylbutyl ITC analog. ≥98% 267.46 C14H21NS2 Ambient 4°C "Lam LKT, Kenney P, Bergstrom CP, et al.  Chem Biol Interact. 1999;127:163-80.

Hecht SS. Chemoprevention by isothiocyanates. J Cell Biochem Suppl. 1995;22:195-209. PMID: 8538199." Not dangerous goods.

LKT T3038 Thienylnonanyl Isothiocyanate 500 mg 2982.1 Thienylbutyl ITC analog. ≥98% 267.46 C14H21NS2 Ambient 4°C "Lam LKT, Kenney P, Bergstrom CP, et al.  Chem Biol Interact. 1999;127:163-80.

Hecht SS. Chemoprevention by isothiocyanates. J Cell Biochem Suppl. 1995;22:195-209. PMID: 8538199." Not dangerous goods.

LKT T3037 Thienylmethyl Isothiocyanate 100 mg 91.7 Thienylbutyl ITC analog. ≥98% 155.24 C6H5NS2 Ambient 4°C "Lam LKT, Kenney P, Bergstrom CP, et al.  Chem Biol Interact. 1999;127:163-80.

Hecht SS. Chemoprevention by isothiocyanates. J Cell Biochem Suppl. 1995;22:195-209. PMID: 8538199." Not dangerous goods.

LKT T3037 Thienylmethyl Isothiocyanate 500 mg 374.5 Thienylbutyl ITC analog. ≥98% 155.24 C6H5NS2 Ambient 4°C "Lam LKT, Kenney P, Bergstrom CP, et al.  Chem Biol Interact. 1999;127:163-80.

Hecht SS. Chemoprevention by isothiocyanates. J Cell Biochem Suppl. 1995;22:195-209. PMID: 8538199." Not dangerous goods.

LKT T3037 Thienylmethyl Isothiocyanate 1 g 659.6 Thienylbutyl ITC analog. ≥98% 155.24 C6H5NS2 Ambient 4°C "Lam LKT, Kenney P, Bergstrom CP, et al.  Chem Biol Interact. 1999;127:163-80.

Hecht SS. Chemoprevention by isothiocyanates. J Cell Biochem Suppl. 1995;22:195-209. PMID: 8538199." Not dangerous goods.

LKT H9715 Hydroxyurea 5 g 58.2 Fetal hemoglobin stimulator; ribonucleotide reductase inhibitor. Hydroxycarbamide; Droxia; Hydrea; Litalir 127-07-1 ≥98% 76.06 CH4N2O2 C(=O)(N)NO Ambient 4°C Soluble in water or hot alcohol. "Amaru Calzada A, Pedrini O, Finazzi G, et al. Givinostat and hydroxyurea synergize in vitro to induce apoptosis of cells from JAK2(V617F) myeloproliferative neoplasm patients. Exp Hematol. 2013 Mar;41(3):253-60.e2. PMID: 23111067.

Vankayala SL, Hargis JC, Woodcock HL. Unlocking the binding and reaction mechanism of hydroxyurea substrates as biological nitric oxide donors. J Chem Inf Model. 2012 May 25;52(5):1288-97. PMID: 22519847.

" Mut., Repr., T Not dangerous goods.

LKT H9715 Hydroxyurea 10 g 110 Fetal hemoglobin stimulator; ribonucleotide reductase inhibitor. Hydroxycarbamide; Droxia; Hydrea; Litalir 127-07-1 ≥98% 76.06 CH4N2O2 C(=O)(N)NO Ambient 4°C Soluble in water or hot alcohol. "Amaru Calzada A, Pedrini O, Finazzi G, et al. Givinostat and hydroxyurea synergize in vitro to induce apoptosis of cells from JAK2(V617F) myeloproliferative neoplasm patients. Exp Hematol. 2013 Mar;41(3):253-60.e2. PMID: 23111067.

Vankayala SL, Hargis JC, Woodcock HL. Unlocking the binding and reaction mechanism of hydroxyurea substrates as biological nitric oxide donors. J Chem Inf Model. 2012 May 25;52(5):1288-97. PMID: 22519847.

" Mut., Repr., T Not dangerous goods.

LKT H9715 Hydroxyurea 50 g 323.6 Fetal hemoglobin stimulator; ribonucleotide reductase inhibitor. Hydroxycarbamide; Droxia; Hydrea; Litalir 127-07-1 ≥98% 76.06 CH4N2O2 C(=O)(N)NO Ambient 4°C Soluble in water or hot alcohol. "Amaru Calzada A, Pedrini O, Finazzi G, et al. Givinostat and hydroxyurea synergize in vitro to induce apoptosis of cells from JAK2(V617F) myeloproliferative neoplasm patients. Exp Hematol. 2013 Mar;41(3):253-60.e2. PMID: 23111067.

Vankayala SL, Hargis JC, Woodcock HL. Unlocking the binding and reaction mechanism of hydroxyurea substrates as biological nitric oxide donors. J Chem Inf Model. 2012 May 25;52(5):1288-97. PMID: 22519847.

" Mut., Repr., T Not dangerous goods.

LKT H9716 (E,Z)-4-Hydroxytamoxifen 5 mg 38.9 SERM. Afimoxifene 68392-35-8 ≥97% 387.51 C26H29NO2 CCC(=C(C1=CC=C(C=C1)O)C2=CC=C(C=C2)OCCN(C)C)C3=CC=CC=C3 Ambient -20°C "Asp ML, Martindale JJ, Metzger JM. Direct, differential effects of tamoxifen, 4-hydroxytamoxifen, and raloxifene on cardiac myocyte contractility and calcium handling. PLoS One. 2013 Oct 24;8(10):e78768. PMID: 24205315.

Kohli L, Kaza N, Coric T, et al. 4-Hydroxytamoxifen induces autophagic death through K-Ras degradation. Cancer Res. 2013 Jul 15;73(14):4395-405. PMID: 23722551.

Schwartz JA, Zhong L, Deighton-Collins S, et al. Mutations targeted to a predicted helix in the extreme carboxyl-terminal region of the human estrogen receptor-alpha alter its response to estradiol and 4-hydroxytamoxifen. J Biol Chem. 2002 Apr 12;277(15):13202-9. Erratum in: J Biol Chem 2002 Jul 5;277(27):24842.  PMID: 11823467.

" Not dangerous goods.

LKT H9716 (E,Z)-4-Hydroxytamoxifen 10 mg 65.5 SERM. Afimoxifene 68392-35-8 ≥97% 387.51 C26H29NO2 CCC(=C(C1=CC=C(C=C1)O)C2=CC=C(C=C2)OCCN(C)C)C3=CC=CC=C3 Ambient -20°C "Asp ML, Martindale JJ, Metzger JM. Direct, differential effects of tamoxifen, 4-hydroxytamoxifen, and raloxifene on cardiac myocyte contractility and calcium handling. PLoS One. 2013 Oct 24;8(10):e78768. PMID: 24205315.

Kohli L, Kaza N, Coric T, et al. 4-Hydroxytamoxifen induces autophagic death through K-Ras degradation. Cancer Res. 2013 Jul 15;73(14):4395-405. PMID: 23722551.

Schwartz JA, Zhong L, Deighton-Collins S, et al. Mutations targeted to a predicted helix in the extreme carboxyl-terminal region of the human estrogen receptor-alpha alter its response to estradiol and 4-hydroxytamoxifen. J Biol Chem. 2002 Apr 12;277(15):13202-9. Erratum in: J Biol Chem 2002 Jul 5;277(27):24842.  PMID: 11823467.

" Not dangerous goods.

LKT H9716 (E,Z)-4-Hydroxytamoxifen 25 mg 133.5 SERM. Afimoxifene 68392-35-8 ≥97% 387.51 C26H29NO2 CCC(=C(C1=CC=C(C=C1)O)C2=CC=C(C=C2)OCCN(C)C)C3=CC=CC=C3 Ambient -20°C "Asp ML, Martindale JJ, Metzger JM. Direct, differential effects of tamoxifen, 4-hydroxytamoxifen, and raloxifene on cardiac myocyte contractility and calcium handling. PLoS One. 2013 Oct 24;8(10):e78768. PMID: 24205315.

Kohli L, Kaza N, Coric T, et al. 4-Hydroxytamoxifen induces autophagic death through K-Ras degradation. Cancer Res. 2013 Jul 15;73(14):4395-405. PMID: 23722551.

Schwartz JA, Zhong L, Deighton-Collins S, et al. Mutations targeted to a predicted helix in the extreme carboxyl-terminal region of the human estrogen receptor-alpha alter its response to estradiol and 4-hydroxytamoxifen. J Biol Chem. 2002 Apr 12;277(15):13202-9. Erratum in: J Biol Chem 2002 Jul 5;277(27):24842.  PMID: 11823467.

" Not dangerous goods.

LKT T3036 Thienylhexyl Isothiocyanate 25 mg 195.2 Thienylbutyl ITC analog. ≥97% 225.38 C11H15NS2 Ambient 4°C "Lam LKT, Kenney P, Bergstrom CP, et al.  Chem Biol Interact. 1999;127:163-80.

Hecht SS. Chemoprevention by isothiocyanates. J Cell Biochem Suppl. 1995;22:195-209. PMID: 8538199." Not dangerous goods.

LKT T3036 Thienylhexyl Isothiocyanate 50 mg 330.1 Thienylbutyl ITC analog. ≥97% 225.38 C11H15NS2 Ambient 4°C "Lam LKT, Kenney P, Bergstrom CP, et al.  Chem Biol Interact. 1999;127:163-80.

Hecht SS. Chemoprevention by isothiocyanates. J Cell Biochem Suppl. 1995;22:195-209. PMID: 8538199." Not dangerous goods.

LKT T3036 Thienylhexyl Isothiocyanate 100 mg 539.7 Thienylbutyl ITC analog. ≥97% 225.38 C11H15NS2 Ambient 4°C "Lam LKT, Kenney P, Bergstrom CP, et al.  Chem Biol Interact. 1999;127:163-80.

Hecht SS. Chemoprevention by isothiocyanates. J Cell Biochem Suppl. 1995;22:195-209. PMID: 8538199." Not dangerous goods.

LKT T3036 Thienylhexyl Isothiocyanate 500 mg 2158.2 Thienylbutyl ITC analog. ≥97% 225.38 C11H15NS2 Ambient 4°C "Lam LKT, Kenney P, Bergstrom CP, et al.  Chem Biol Interact. 1999;127:163-80.

Hecht SS. Chemoprevention by isothiocyanates. J Cell Biochem Suppl. 1995;22:195-209. PMID: 8538199." Not dangerous goods.

LKT H9717 Hydroxyzine Dihydrochloride 5 g 58.9 FIASMA, histamine H1 inverse agonist, 5-HT2A, D1/2, α1-adrenergic antagonist. "Ethanol, 2-(2-(4-((4-chlorophenyl)phenylmethyl)-1-

piperazinyl)ethoxy)-, dihydrochloride" Alamon; Atarax; Aterax; Durrax; Orgatrax; Quiess; Vistaril Parental. 2192-20-3 ≥98% 447.83 C21H27ClN2O2 2HCl C1CN(CCN1CCOCCO)C(C2=CC=CC=C2)C3=CC=C(C=C3)Cl.Cl.Cl Ambient Ambient Soluble in water (<700mg/mL), ethanol (220 mg/mL), chloroform (60mg/mL) or acetone (2mg/mL). "Llorca PM, Spadone C, Sol O, et al. Efficacy and safety of hydroxyzine in the treatment of generalized anxiety disorder: a 3-month double-blind study. J Clin Psychiatry. 2002 Nov;63(11):1020-7. PMID: 12444816.

Minogiannis P, El-Mansoury M, Betances JA, et al. Hydroxyzine inhibits neurogenic bladder mast cell activation. Int J Immunopharmacol. 1998 Oct;20(10):553-63. PMID: 9839659.

Haraguchi K, Ito K, Kotaki H, et al. Prediction of drug-induced catalepsy based on dopamine D1, D2, and muscarinic acetylcholine receptor occupancies. Drug Metab Dispos. 1997 Jun;25(6):675-84. PMID: 9193868.

Snowman AM, Snyder SH. Cetirizine: actions on neurotransmitter receptors. J Allergy Clin Immunol. 1990 Dec;86(6 Pt 2):1025-8. PMID: 1979798.

" Xn, Not dangerous goods.

LKT H9717 Hydroxyzine Dihydrochloride 10 g 94.4 FIASMA, histamine H1 inverse agonist, 5-HT2A, D1/2, α1-adrenergic antagonist. "Ethanol, 2-(2-(4-((4-chlorophenyl)phenylmethyl)-1-

piperazinyl)ethoxy)-, dihydrochloride" Alamon; Atarax; Aterax; Durrax; Orgatrax; Quiess; Vistaril Parental. 2192-20-3 ≥98% 447.83 C21H27ClN2O2 2HCl C1CN(CCN1CCOCCO)C(C2=CC=CC=C2)C3=CC=C(C=C3)Cl.Cl.Cl Ambient Ambient Soluble in water (<700mg/mL), ethanol (220 mg/mL), chloroform (60mg/mL) or acetone (2mg/mL). "Llorca PM, Spadone C, Sol O, et al. Efficacy and safety of hydroxyzine in the treatment of generalized anxiety disorder: a 3-month double-blind study. J Clin Psychiatry. 2002 Nov;63(11):1020-7. PMID: 12444816.

Minogiannis P, El-Mansoury M, Betances JA, et al. Hydroxyzine inhibits neurogenic bladder mast cell activation. Int J Immunopharmacol. 1998 Oct;20(10):553-63. PMID: 9839659.

Haraguchi K, Ito K, Kotaki H, et al. Prediction of drug-induced catalepsy based on dopamine D1, D2, and muscarinic acetylcholine receptor occupancies. Drug Metab Dispos. 1997 Jun;25(6):675-84. PMID: 9193868.

Snowman AM, Snyder SH. Cetirizine: actions on neurotransmitter receptors. J Allergy Clin Immunol. 1990 Dec;86(6 Pt 2):1025-8. PMID: 1979798.

" Xn, Not dangerous goods.

LKT H9718 2-Hydroxyflutamide 10 mg 95.1 Non-steroid; AR antagonist. 2-Hydroxy-2-methyl-N-[4-nitro-3-(trifluoromethyl)phenyl]prop* Hydroxyniphtholide 52806-53-8 ≥98% 292.21 C11H11F3N2O4 CC(C)(C(=O)NC1=CC(=C(C=C1)[N+](=O)[O-])C(F)(F)F)O Ambient -20°C "Kawabata R, Oie S, Oka T, et al. Hydroxyflutamide enhances cellular sensitivity to 5-fluorouracil by suppressing thymidylate synthase expression in bicalutamide-resistant human prostate cancer cells. Int J Oncol. 2011 Mar;38(3):665-76. PMID: 21243325.

Hofbauer LC, Ten RM, Khosla S. The anti-androgen hydroxyflutamide and androgens inhibit interleukin-6 production by an androgen-responsive human osteoblastic cell line. J Bone Miner Res. 1999 Aug;14(8):1330-7. PMID: 10457265.

Furr BJ, Valcaccia B, Curry B, et al. ICI 176,334: a novel non-steroidal, peripherally selective antiandrogen. J Endocrinol. 1987 Jun;113(3):R7-9. PMID: 3625091.

" Not dangerous goods.

LKT H9718 2-Hydroxyflutamide 25 mg 203.8 Non-steroid; AR antagonist. 2-Hydroxy-2-methyl-N-[4-nitro-3-(trifluoromethyl)phenyl]prop* Hydroxyniphtholide 52806-53-8 ≥98% 292.21 C11H11F3N2O4 CC(C)(C(=O)NC1=CC(=C(C=C1)[N+](=O)[O-])C(F)(F)F)O Ambient -20°C "Kawabata R, Oie S, Oka T, et al. Hydroxyflutamide enhances cellular sensitivity to 5-fluorouracil by suppressing thymidylate synthase expression in bicalutamide-resistant human prostate cancer cells. Int J Oncol. 2011 Mar;38(3):665-76. PMID: 21243325.

Hofbauer LC, Ten RM, Khosla S. The anti-androgen hydroxyflutamide and androgens inhibit interleukin-6 production by an androgen-responsive human osteoblastic cell line. J Bone Miner Res. 1999 Aug;14(8):1330-7. PMID: 10457265.

Furr BJ, Valcaccia B, Curry B, et al. ICI 176,334: a novel non-steroidal, peripherally selective antiandrogen. J Endocrinol. 1987 Jun;113(3):R7-9. PMID: 3625091.

" Not dangerous goods.

LKT H9718 2-Hydroxyflutamide 100 mg 611.5 Non-steroid; AR antagonist. 2-Hydroxy-2-methyl-N-[4-nitro-3-(trifluoromethyl)phenyl]prop* Hydroxyniphtholide 52806-53-8 ≥98% 292.21 C11H11F3N2O4 CC(C)(C(=O)NC1=CC(=C(C=C1)[N+](=O)[O-])C(F)(F)F)O Ambient -20°C "Kawabata R, Oie S, Oka T, et al. Hydroxyflutamide enhances cellular sensitivity to 5-fluorouracil by suppressing thymidylate synthase expression in bicalutamide-resistant human prostate cancer cells. Int J Oncol. 2011 Mar;38(3):665-76. PMID: 21243325.

Hofbauer LC, Ten RM, Khosla S. The anti-androgen hydroxyflutamide and androgens inhibit interleukin-6 production by an androgen-responsive human osteoblastic cell line. J Bone Miner Res. 1999 Aug;14(8):1330-7. PMID: 10457265.

Furr BJ, Valcaccia B, Curry B, et al. ICI 176,334: a novel non-steroidal, peripherally selective antiandrogen. J Endocrinol. 1987 Jun;113(3):R7-9. PMID: 3625091.

" Not dangerous goods.

LKT T3035 Thienylheptyl Isothiocyanate 10 mg 196.8 Thienylbutyl ITC analog. ≥95% 239.4 C12H17NS2 Ambient 4°C "Lam LKT, Kenney P, Bergstrom CP, et al.  Chem Biol Interact. 1999;127:163-80.

Hecht SS. Chemoprevention by isothiocyanates. J Cell Biochem Suppl. 1995;22:195-209. PMID: 8538199." Not dangerous goods.

LKT T3035 Thienylheptyl Isothiocyanate 25 mg 443.8 Thienylbutyl ITC analog. ≥95% 239.4 C12H17NS2 Ambient 4°C "Lam LKT, Kenney P, Bergstrom CP, et al.  Chem Biol Interact. 1999;127:163-80.

Hecht SS. Chemoprevention by isothiocyanates. J Cell Biochem Suppl. 1995;22:195-209. PMID: 8538199." Not dangerous goods.

LKT T3035 Thienylheptyl Isothiocyanate 50 mg 794.3 Thienylbutyl ITC analog. ≥95% 239.4 C12H17NS2 Ambient 4°C "Lam LKT, Kenney P, Bergstrom CP, et al.  Chem Biol Interact. 1999;127:163-80.

Hecht SS. Chemoprevention by isothiocyanates. J Cell Biochem Suppl. 1995;22:195-209. PMID: 8538199." Not dangerous goods.

LKT T3035 Thienylheptyl Isothiocyanate 100 mg 1364.2 Thienylbutyl ITC analog. ≥95% 239.4 C12H17NS2 Ambient 4°C "Lam LKT, Kenney P, Bergstrom CP, et al.  Chem Biol Interact. 1999;127:163-80.

Hecht SS. Chemoprevention by isothiocyanates. J Cell Biochem Suppl. 1995;22:195-209. PMID: 8538199." Not dangerous goods.

LKT T3034 Thienylethyl Isothiocyanate 25 mg 103.4 Thienylbutyl ITC analog. ≥98% 169.27 C7H7NS2 Ambient 4°C "Lam LKT, Kenney P, Bergstrom CP, et al.  Chem Biol Interact. 1999;127:163-80.

Hecht SS. Chemoprevention by isothiocyanates. J Cell Biochem Suppl. 1995;22:195-209. PMID: 8538199." Not dangerous goods.

LKT T3034 Thienylethyl Isothiocyanate 50 mg 187.8 Thienylbutyl ITC analog. ≥98% 169.27 C7H7NS2 Ambient 4°C "Lam LKT, Kenney P, Bergstrom CP, et al.  Chem Biol Interact. 1999;127:163-80.

Hecht SS. Chemoprevention by isothiocyanates. J Cell Biochem Suppl. 1995;22:195-209. PMID: 8538199." Not dangerous goods.

LKT T3034 Thienylethyl Isothiocyanate 100 mg 330.1 Thienylbutyl ITC analog. ≥98% 169.27 C7H7NS2 Ambient 4°C "Lam LKT, Kenney P, Bergstrom CP, et al.  Chem Biol Interact. 1999;127:163-80.

Hecht SS. Chemoprevention by isothiocyanates. J Cell Biochem Suppl. 1995;22:195-209. PMID: 8538199." Not dangerous goods.

LKT T3034 Thienylethyl Isothiocyanate 500 mg 1348.7 Thienylbutyl ITC analog. ≥98% 169.27 C7H7NS2 Ambient 4°C "Lam LKT, Kenney P, Bergstrom CP, et al.  Chem Biol Interact. 1999;127:163-80.

Hecht SS. Chemoprevention by isothiocyanates. J Cell Biochem Suppl. 1995;22:195-209. PMID: 8538199." Not dangerous goods.

LKT T3033 Thienyldodecyl Isothiocyanate 25 mg 246.4 Thienylbutyl ITC analog. ≥98% 309.54 C17H27NS2 Ambient 4°C "Lam LKT, Kenney P, Bergstrom CP, et al.  Chem Biol Interact. 1999;127:163-80.

Hecht SS. Chemoprevention by isothiocyanates. J Cell Biochem Suppl. 1995;22:195-209. PMID: 8538199." Not dangerous goods.

LKT T3033 Thienyldodecyl Isothiocyanate 50 mg 442.3 Thienylbutyl ITC analog. ≥98% 309.54 C17H27NS2 Ambient 4°C "Lam LKT, Kenney P, Bergstrom CP, et al.  Chem Biol Interact. 1999;127:163-80.

Hecht SS. Chemoprevention by isothiocyanates. J Cell Biochem Suppl. 1995;22:195-209. PMID: 8538199." Not dangerous goods.

LKT T3033 Thienyldodecyl Isothiocyanate 100 mg 791.9 Thienylbutyl ITC analog. ≥98% 309.54 C17H27NS2 Ambient 4°C "Lam LKT, Kenney P, Bergstrom CP, et al.  Chem Biol Interact. 1999;127:163-80.

Hecht SS. Chemoprevention by isothiocyanates. J Cell Biochem Suppl. 1995;22:195-209. PMID: 8538199." Not dangerous goods.

LKT T3033 Thienyldodecyl Isothiocyanate 500 mg 2982.1 Thienylbutyl ITC analog. ≥98% 309.54 C17H27NS2 Ambient 4°C "Lam LKT, Kenney P, Bergstrom CP, et al.  Chem Biol Interact. 1999;127:163-80.

Hecht SS. Chemoprevention by isothiocyanates. J Cell Biochem Suppl. 1995;22:195-209. PMID: 8538199." Not dangerous goods.

LKT T3032 Thienyldecyl Isothiocyanate 25 mg 203.7 Thienylbutyl ITC analog. ≥95% 281.48 C15H23NS2 Ambient 4°C "Lam LKT, Kenney P, Bergstrom CP, et al.  Chem Biol Interact. 1999;127:163-80.

Hecht SS. Chemoprevention by isothiocyanates. J Cell Biochem Suppl. 1995;22:195-209. PMID: 8538199." Not dangerous goods.

LKT T3032 Thienyldecyl Isothiocyanate 50 mg 342.2 Thienylbutyl ITC analog. ≥95% 281.48 C15H23NS2 Ambient 4°C "Lam LKT, Kenney P, Bergstrom CP, et al.  Chem Biol Interact. 1999;127:163-80.

Hecht SS. Chemoprevention by isothiocyanates. J Cell Biochem Suppl. 1995;22:195-209. PMID: 8538199." Not dangerous goods.

LKT T3032 Thienyldecyl Isothiocyanate 100 mg 554.8 Thienylbutyl ITC analog. ≥95% 281.48 C15H23NS2 Ambient 4°C "Lam LKT, Kenney P, Bergstrom CP, et al.  Chem Biol Interact. 1999;127:163-80.

Hecht SS. Chemoprevention by isothiocyanates. J Cell Biochem Suppl. 1995;22:195-209. PMID: 8538199." Not dangerous goods.

LKT T3032 Thienyldecyl Isothiocyanate 500 mg 2182.2 Thienylbutyl ITC analog. ≥95% 281.48 C15H23NS2 Ambient 4°C "Lam LKT, Kenney P, Bergstrom CP, et al.  Chem Biol Interact. 1999;127:163-80.

Hecht SS. Chemoprevention by isothiocyanates. J Cell Biochem Suppl. 1995;22:195-209. PMID: 8538199." Not dangerous goods.

LKT H9759 Hypaconitine 10 mg 147 Diterpene alkaloid found in Aconitum; voltage-gated Na+ channel modulator. "16,16-trimethoxy-4-(methoxymethyl)-20-methyl- 8-acetatebenzoate-(1-alpha,6-alpha,14-alpha,15-alpha,16-beta)-Aconitane-8,13,14,15-tetraol

" 6900-87-4 ≥90% 615.71 C33H45NO10 CC(=O)OC12C3C(CC(C3OC(=O)C4=CC=CC=C4)(C(C1O)OC)O)C56C(CCC7(C5C(C2C6N(C7)C)OC)COC)OC Ambient -20°C "Muroi M, Kimura I, Kimura M. Blocking effects of hypaconitine and aconitine on nerve action potentials in phrenic nerve-diaphragm muscles of mice. Neuropharmacology. 1990 Jun;29(6):567-72. PMID: 2385329.

Kimura M, Muroi M, Kimura I, et al. Hypaconitine, the dominant constituent responsible for the neuromuscular blocking action of the Japanese-sino medicine ""bushi"" (aconite root). Jpn J Pharmacol. 1988 Oct;48(2):290-3. PMID: 3210453.

" Carc., Xn, Xi "UN number: 1544      Class: 6.1      Packing group: II

Proper shipping name: Alkaloids, solid, n.o.s. (Hypaconitine)

Poison Inhalation Hazard: No"

LKT H9759 Hypaconitine 25 mg 273.1 Diterpene alkaloid found in Aconitum; voltage-gated Na+ channel modulator. "16,16-trimethoxy-4-(methoxymethyl)-20-methyl- 8-acetatebenzoate-(1-alpha,6-alpha,14-alpha,15-alpha,16-beta)-Aconitane-8,13,14,15-tetraol

" 6900-87-4 ≥90% 615.71 C33H45NO10 CC(=O)OC12C3C(CC(C3OC(=O)C4=CC=CC=C4)(C(C1O)OC)O)C56C(CCC7(C5C(C2C6N(C7)C)OC)COC)OC Ambient -20°C "Muroi M, Kimura I, Kimura M. Blocking effects of hypaconitine and aconitine on nerve action potentials in phrenic nerve-diaphragm muscles of mice. Neuropharmacology. 1990 Jun;29(6):567-72. PMID: 2385329.

Kimura M, Muroi M, Kimura I, et al. Hypaconitine, the dominant constituent responsible for the neuromuscular blocking action of the Japanese-sino medicine ""bushi"" (aconite root). Jpn J Pharmacol. 1988 Oct;48(2):290-3. PMID: 3210453.

" Carc., Xn, Xi "UN number: 1544      Class: 6.1      Packing group: II

Proper shipping name: Alkaloids, solid, n.o.s. (Hypaconitine)

Poison Inhalation Hazard: No"

LKT T3031 Thienylbutyl Isothiocyanate 25 mg 192.4 ITC. 288323-36-4 ≥96% 197.32 C9H11NS2 Ambient 4°C "Lam LKT, Kenney P, Bergstrom CP, et al.  Chem Biol Interact. 1999;127:163-80.

Hecht SS. Chemoprevention by isothiocyanates. J Cell Biochem Suppl. 1995;22:195-209. PMID: 8538199." Not dangerous goods.

LKT T3031 Thienylbutyl Isothiocyanate 50 mg 323.7 ITC. 288323-36-4 ≥96% 197.32 C9H11NS2 Ambient 4°C "Lam LKT, Kenney P, Bergstrom CP, et al.  Chem Biol Interact. 1999;127:163-80.

Hecht SS. Chemoprevention by isothiocyanates. J Cell Biochem Suppl. 1995;22:195-209. PMID: 8538199." Not dangerous goods.

LKT H9759 Hypaconitine 100 mg 840.1 Diterpene alkaloid found in Aconitum; voltage-gated Na+ channel modulator. "16,16-trimethoxy-4-(methoxymethyl)-20-methyl- 8-acetatebenzoate-(1-alpha,6-alpha,14-alpha,15-alpha,16-beta)-Aconitane-8,13,14,15-tetraol

" 6900-87-4 ≥90% 615.71 C33H45NO10 CC(=O)OC12C3C(CC(C3OC(=O)C4=CC=CC=C4)(C(C1O)OC)O)C56C(CCC7(C5C(C2C6N(C7)C)OC)COC)OC Ambient -20°C "Muroi M, Kimura I, Kimura M. Blocking effects of hypaconitine and aconitine on nerve action potentials in phrenic nerve-diaphragm muscles of mice. Neuropharmacology. 1990 Jun;29(6):567-72. PMID: 2385329.

Kimura M, Muroi M, Kimura I, et al. Hypaconitine, the dominant constituent responsible for the neuromuscular blocking action of the Japanese-sino medicine ""bushi"" (aconite root). Jpn J Pharmacol. 1988 Oct;48(2):290-3. PMID: 3210453.

" Carc., Xn, Xi "UN number: 1544      Class: 6.1      Packing group: II

Proper shipping name: Alkaloids, solid, n.o.s. (Hypaconitine)

Poison Inhalation Hazard: No"

LKT T3031 Thienylbutyl Isothiocyanate 100 mg 541.2 ITC. 288323-36-4 ≥96% 197.32 C9H11NS2 Ambient 4°C "Lam LKT, Kenney P, Bergstrom CP, et al.  Chem Biol Interact. 1999;127:163-80.

Hecht SS. Chemoprevention by isothiocyanates. J Cell Biochem Suppl. 1995;22:195-209. PMID: 8538199." Not dangerous goods.

LKT T3031 Thienylbutyl Isothiocyanate 500 mg 2158.2 ITC. 288323-36-4 ≥96% 197.32 C9H11NS2 Ambient 4°C "Lam LKT, Kenney P, Bergstrom CP, et al.  Chem Biol Interact. 1999;127:163-80.

Hecht SS. Chemoprevention by isothiocyanates. J Cell Biochem Suppl. 1995;22:195-209. PMID: 8538199." Not dangerous goods.

LKT T2970 Thrombin Receptor Agonist Peptide 1 mg 216.1 Peptide; PAR1 agonist. 137339-65-2 ≥95% 1739.96 C81H118N20O23 CC(C)CC(C(=O)NC(CC(C)C)C(=O)NC(CCCNC(=N)N)C(=O)NC(CC(=O)N)C(=O)N1CCCC1C(=O)NC(CC(=O)N)C(=O)NC(CC(=O)O)C(=O)NC(CCCCN)C(=O)NC(CC2=CC=C(C=C2)O)C(=O)NC(CCC(=O)O)C(=O)N3CCCC3C(=O)NC(CC4=CC=CC=C4)C(=O)O)NC(=O)C(CC5=CC=CC=C5)NC(=O)C(CO)N Ambient -20°C "Windeløv NA, Sørensen AM, Perner A, et al. Platelet aggregation following trauma: a prospective study. Blood Coagul Fibrinolysis. 2014 Jan;25(1):67-73. PMID: 23945060.

Kreutz RP, Breall JA, Kreutz Y, et al. Protease activated receptor-1 (PAR-1) mediated platelet aggregation is dependent on clopidogrel response. Thromb Res. 2012 Aug;130(2):198-202. PMID: 22459907.

" Not dangerous goods.

LKT T2970 Thrombin Receptor Agonist Peptide 2 mg 365.9 Peptide; PAR1 agonist. 137339-65-2 ≥95% 1739.96 C81H118N20O23 CC(C)CC(C(=O)NC(CC(C)C)C(=O)NC(CCCNC(=N)N)C(=O)NC(CC(=O)N)C(=O)N1CCCC1C(=O)NC(CC(=O)N)C(=O)NC(CC(=O)O)C(=O)NC(CCCCN)C(=O)NC(CC2=CC=C(C=C2)O)C(=O)NC(CCC(=O)O)C(=O)N3CCCC3C(=O)NC(CC4=CC=CC=C4)C(=O)O)NC(=O)C(CC5=CC=CC=C5)NC(=O)C(CO)N Ambient -20°C "Windeløv NA, Sørensen AM, Perner A, et al. Platelet aggregation following trauma: a prospective study. Blood Coagul Fibrinolysis. 2014 Jan;25(1):67-73. PMID: 23945060.

Kreutz RP, Breall JA, Kreutz Y, et al. Protease activated receptor-1 (PAR-1) mediated platelet aggregation is dependent on clopidogrel response. Thromb Res. 2012 Aug;130(2):198-202. PMID: 22459907.

" Not dangerous goods.

LKT T2970 Thrombin Receptor Agonist Peptide 5 mg 648.2 Peptide; PAR1 agonist. 137339-65-2 ≥95% 1739.96 C81H118N20O23 CC(C)CC(C(=O)NC(CC(C)C)C(=O)NC(CCCNC(=N)N)C(=O)NC(CC(=O)N)C(=O)N1CCCC1C(=O)NC(CC(=O)N)C(=O)NC(CC(=O)O)C(=O)NC(CCCCN)C(=O)NC(CC2=CC=C(C=C2)O)C(=O)NC(CCC(=O)O)C(=O)N3CCCC3C(=O)NC(CC4=CC=CC=C4)C(=O)O)NC(=O)C(CC5=CC=CC=C5)NC(=O)C(CO)N Ambient -20°C "Windeløv NA, Sørensen AM, Perner A, et al. Platelet aggregation following trauma: a prospective study. Blood Coagul Fibrinolysis. 2014 Jan;25(1):67-73. PMID: 23945060.

Kreutz RP, Breall JA, Kreutz Y, et al. Protease activated receptor-1 (PAR-1) mediated platelet aggregation is dependent on clopidogrel response. Thromb Res. 2012 Aug;130(2):198-202. PMID: 22459907.

" Not dangerous goods.

LKT T2935 Thiamphenicol 1 g 65.6 Chloramphenicol derivative; protein translation inhibitor, peptidyl transferase inhibitor. 2,2-Dichloro-N-[(1R,2R)-2-hydroxy-1-(hydroxy- methyl)-2-[4-(methylsulfonyl)phenyl]ethyl]acetamide Hyrazin; Igralin; Neomyson; Rigelon; Urfamycine; Urophenil; Methylsulfonyl chloramphenicol 15318-45-3 ≥98% 356.22 C12H15Cl2NO5S CS(=O)(=O)C1=CC=C(C=C1)C(C(CO)NC(=O)C(Cl)Cl)O Ambient Ambient Soluble in water and alcohol. "Raymond J, Boutros N, Bergeret M. Role of thiamphenicol in the treatment of community-acquired lung infections. Med Trop (Mars). 2004;64(1):33-8. PMID: 15224555.

Marchese A, Debbia EA, Tonoli E, et al. In vitro activity of thiamphenicol against multiresistant Streptococcus pneumoniae, Haemophilus influenzae and Staphylococcus aureus in Italy. J Chemother. 2002 Dec;14(6):554-61. PMID: 12583545.

" Not dangerous goods.

LKT T2935 Thiamphenicol 5 g 168.7 Chloramphenicol derivative; protein translation inhibitor, peptidyl transferase inhibitor. 2,2-Dichloro-N-[(1R,2R)-2-hydroxy-1-(hydroxy- methyl)-2-[4-(methylsulfonyl)phenyl]ethyl]acetamide Hyrazin; Igralin; Neomyson; Rigelon; Urfamycine; Urophenil; Methylsulfonyl chloramphenicol 15318-45-3 ≥98% 356.22 C12H15Cl2NO5S CS(=O)(=O)C1=CC=C(C=C1)C(C(CO)NC(=O)C(Cl)Cl)O Ambient Ambient Soluble in water and alcohol. "Raymond J, Boutros N, Bergeret M. Role of thiamphenicol in the treatment of community-acquired lung infections. Med Trop (Mars). 2004;64(1):33-8. PMID: 15224555.

Marchese A, Debbia EA, Tonoli E, et al. In vitro activity of thiamphenicol against multiresistant Streptococcus pneumoniae, Haemophilus influenzae and Staphylococcus aureus in Italy. J Chemother. 2002 Dec;14(6):554-61. PMID: 12583545.

" Not dangerous goods.

LKT T2935 Thiamphenicol 25 g 375.1 Chloramphenicol derivative; protein translation inhibitor, peptidyl transferase inhibitor. 2,2-Dichloro-N-[(1R,2R)-2-hydroxy-1-(hydroxy- methyl)-2-[4-(methylsulfonyl)phenyl]ethyl]acetamide Hyrazin; Igralin; Neomyson; Rigelon; Urfamycine; Urophenil; Methylsulfonyl chloramphenicol 15318-45-3 ≥98% 356.22 C12H15Cl2NO5S CS(=O)(=O)C1=CC=C(C=C1)C(C(CO)NC(=O)C(Cl)Cl)O Ambient Ambient Soluble in water and alcohol. "Raymond J, Boutros N, Bergeret M. Role of thiamphenicol in the treatment of community-acquired lung infections. Med Trop (Mars). 2004;64(1):33-8. PMID: 15224555.

Marchese A, Debbia EA, Tonoli E, et al. In vitro activity of thiamphenicol against multiresistant Streptococcus pneumoniae, Haemophilus influenzae and Staphylococcus aureus in Italy. J Chemother. 2002 Dec;14(6):554-61. PMID: 12583545.

" Not dangerous goods.

LKT T2934 Thiamphenicol Palmitate 5 g 133.2 Chloramphenicol derivative; protein translation inhibitor, peptidyl transferase inhibitor. 52628-58-7 ≥98% 594.63 C28H45Cl2NO6S CCCCCCCCCCCCCCCC(=O)OC(C1=CC=C(C=C1)S(=O)(=O)C)C(CO)NC(=O)C(Cl)Cl Ambient Ambient "Raymond J, Boutros N, Bergeret M. Role of thiamphenicol in the treatment of community-acquired lung infections. Med Trop (Mars). 2004;64(1):33-8. PMID: 15224555.

Marchese A, Debbia EA, Tonoli E, et al. In vitro activity of thiamphenicol against multiresistant Streptococcus pneumoniae, Haemophilus influenzae and Staphylococcus aureus in Italy. J Chemother. 2002 Dec;14(6):554-61. PMID: 12583545.

" Not dangerous goods.

LKT H9763 Hypoxanthine 5 g 26.3 Endogenous purine derivative of xanthine. 1,7-Dihydro-6H-purin-6-one purin-6(1H)-one; Sarcine; Sarkin 68-94-0 ≥98% 136.11 C5H4N4O C1=NC2=C(N1)C(=O)N=CN2 Ambient Ambient Soluble in dil acids and alkalies. "Ipata PL, Balestri F. The functional logic of cytosolic 5'-nucleotidases. Curr Med Chem. 2013;20(34):4205-16. PMID: 23992316.

Okamoto K, Kusano T, Nishino T. Chemical nature and reaction mechanisms of the molybdenum cofactor of xanthine oxidoreductase. Curr Pharm Des. 2013;19(14):2606-14. PMID: 23116398.

Lawal AT, Adeloju SB. Progress and recent advances in fabrication and utilization of hypoxanthine biosensors for meat and fish quality assessment: a review. Talanta. 2012 Oct 15;100:217-28. PMID: 23141330.

" Xn, Xi Not dangerous goods.

LKT T2934 Thiamphenicol Palmitate 25 g 373.7 Chloramphenicol derivative; protein translation inhibitor, peptidyl transferase inhibitor. 52628-58-7 ≥98% 594.63 C28H45Cl2NO6S CCCCCCCCCCCCCCCC(=O)OC(C1=CC=C(C=C1)S(=O)(=O)C)C(CO)NC(=O)C(Cl)Cl Ambient Ambient "Raymond J, Boutros N, Bergeret M. Role of thiamphenicol in the treatment of community-acquired lung infections. Med Trop (Mars). 2004;64(1):33-8. PMID: 15224555.

Marchese A, Debbia EA, Tonoli E, et al. In vitro activity of thiamphenicol against multiresistant Streptococcus pneumoniae, Haemophilus influenzae and Staphylococcus aureus in Italy. J Chemother. 2002 Dec;14(6):554-61. PMID: 12583545.

" Not dangerous goods.

LKT H9763 Hypoxanthine 25 g 52.5 Endogenous purine derivative of xanthine. 1,7-Dihydro-6H-purin-6-one purin-6(1H)-one; Sarcine; Sarkin 68-94-0 ≥98% 136.11 C5H4N4O C1=NC2=C(N1)C(=O)N=CN2 Ambient Ambient Soluble in dil acids and alkalies. "Ipata PL, Balestri F. The functional logic of cytosolic 5'-nucleotidases. Curr Med Chem. 2013;20(34):4205-16. PMID: 23992316.

Okamoto K, Kusano T, Nishino T. Chemical nature and reaction mechanisms of the molybdenum cofactor of xanthine oxidoreductase. Curr Pharm Des. 2013;19(14):2606-14. PMID: 23116398.

Lawal AT, Adeloju SB. Progress and recent advances in fabrication and utilization of hypoxanthine biosensors for meat and fish quality assessment: a review. Talanta. 2012 Oct 15;100:217-28. PMID: 23141330.

" Xn, Xi Not dangerous goods.

LKT H9763 Hypoxanthine 100 g 210 Endogenous purine derivative of xanthine. 1,7-Dihydro-6H-purin-6-one purin-6(1H)-one; Sarcine; Sarkin 68-94-0 ≥98% 136.11 C5H4N4O C1=NC2=C(N1)C(=O)N=CN2 Ambient Ambient Soluble in dil acids and alkalies. "Ipata PL, Balestri F. The functional logic of cytosolic 5'-nucleotidases. Curr Med Chem. 2013;20(34):4205-16. PMID: 23992316.

Okamoto K, Kusano T, Nishino T. Chemical nature and reaction mechanisms of the molybdenum cofactor of xanthine oxidoreductase. Curr Pharm Des. 2013;19(14):2606-14. PMID: 23116398.

Lawal AT, Adeloju SB. Progress and recent advances in fabrication and utilization of hypoxanthine biosensors for meat and fish quality assessment: a review. Talanta. 2012 Oct 15;100:217-28. PMID: 23141330.

" Xn, Xi Not dangerous goods.

LKT H9801 Hyaluronic Acid Sodium 100 mg 57.6 Endogenous anionic non-sulfated glycosaminoglycan, found in connective tissue and synovial fluid, binds cell surface proteins. ARTZ; Equron; Healon; Hyalgan; Ial; Provisc; Synacid 9067-32-7 ≥95% 1000000 (C14H20NO11Na)n CC(=O)NC1C(C(C(OC1O)CO)O)OC2C(C(C(C(O2)C(=O)O)OC3C(C(C(C(O3)CO)O)OC4C(C(C(C(O4)C(=O)O)O)O)O)NC(=O)C)O)O.[Na+] Hygroscopic, store under inert gas. Ambient Ambient Soluble in water (5mg/mL).  Soluble in water up to 1%, using ice-water it will dissolve faster than in room-temp water, may take 24 hours to be completely transparent. "Chen B, Miller RJ, Dhal PK. Hyaluronic acid-based drug conjugates: state-of-the-art and perspectives. J Biomed Nanotechnol. 2014 Jan;10(1):4-16. PMID: 24724495.

Rostami S, Parsian H. Hyaluronic Acid: from biochemical characteristics to its clinical translation in assessment of liver fibrosis. Hepat Mon. 2013 Dec 14;13(12):e13787. PMID: 24403913.

Yung S, Cheung KF, Zhang Q, et al. Mediators of inflammation and their effect on resident renal cells: implications in lupus nephritis. Clin Dev Immunol. 2013;2013:317682. PMID: 24171032.

Josefsson A, Adamo H, Hammarsten P, et al. Prostate cancer increases hyaluronan in surrounding nonmalignant stroma, and this response is associated with tumor growth and an unfavorable outcome. Am J Pathol. 2011 Oct;179(4):1961-8. PMID: 21854754.

Toole BP. Hyaluronan is not just a goo! J Clin Invest. 2000 Aug;106(3):335-6. PMID: 10930435.

" None Not dangerous goods.

LKT H9801 Hyaluronic Acid Sodium 500 mg 173.3 Endogenous anionic non-sulfated glycosaminoglycan, found in connective tissue and synovial fluid, binds cell surface proteins. ARTZ; Equron; Healon; Hyalgan; Ial; Provisc; Synacid 9067-32-7 ≥95% 1000000 (C14H20NO11Na)n CC(=O)NC1C(C(C(OC1O)CO)O)OC2C(C(C(C(O2)C(=O)O)OC3C(C(C(C(O3)CO)O)OC4C(C(C(C(O4)C(=O)O)O)O)O)NC(=O)C)O)O.[Na+] Hygroscopic, store under inert gas. Ambient Ambient Soluble in water (5mg/mL).  Soluble in water up to 1%, using ice-water it will dissolve faster than in room-temp water, may take 24 hours to be completely transparent. "Chen B, Miller RJ, Dhal PK. Hyaluronic acid-based drug conjugates: state-of-the-art and perspectives. J Biomed Nanotechnol. 2014 Jan;10(1):4-16. PMID: 24724495.

Rostami S, Parsian H. Hyaluronic Acid: from biochemical characteristics to its clinical translation in assessment of liver fibrosis. Hepat Mon. 2013 Dec 14;13(12):e13787. PMID: 24403913.

Yung S, Cheung KF, Zhang Q, et al. Mediators of inflammation and their effect on resident renal cells: implications in lupus nephritis. Clin Dev Immunol. 2013;2013:317682. PMID: 24171032.

Josefsson A, Adamo H, Hammarsten P, et al. Prostate cancer increases hyaluronan in surrounding nonmalignant stroma, and this response is associated with tumor growth and an unfavorable outcome. Am J Pathol. 2011 Oct;179(4):1961-8. PMID: 21854754.

Toole BP. Hyaluronan is not just a goo! J Clin Invest. 2000 Aug;106(3):335-6. PMID: 10930435.

" None Not dangerous goods.

LKT H9801 Hyaluronic Acid Sodium 1 g 288.8 Endogenous anionic non-sulfated glycosaminoglycan, found in connective tissue and synovial fluid, binds cell surface proteins. ARTZ; Equron; Healon; Hyalgan; Ial; Provisc; Synacid 9067-32-7 ≥95% 1000000 (C14H20NO11Na)n CC(=O)NC1C(C(C(OC1O)CO)O)OC2C(C(C(C(O2)C(=O)O)OC3C(C(C(C(O3)CO)O)OC4C(C(C(C(O4)C(=O)O)O)O)O)NC(=O)C)O)O.[Na+] Hygroscopic, store under inert gas. Ambient Ambient Soluble in water (5mg/mL).  Soluble in water up to 1%, using ice-water it will dissolve faster than in room-temp water, may take 24 hours to be completely transparent. "Chen B, Miller RJ, Dhal PK. Hyaluronic acid-based drug conjugates: state-of-the-art and perspectives. J Biomed Nanotechnol. 2014 Jan;10(1):4-16. PMID: 24724495.

Rostami S, Parsian H. Hyaluronic Acid: from biochemical characteristics to its clinical translation in assessment of liver fibrosis. Hepat Mon. 2013 Dec 14;13(12):e13787. PMID: 24403913.

Yung S, Cheung KF, Zhang Q, et al. Mediators of inflammation and their effect on resident renal cells: implications in lupus nephritis. Clin Dev Immunol. 2013;2013:317682. PMID: 24171032.

Josefsson A, Adamo H, Hammarsten P, et al. Prostate cancer increases hyaluronan in surrounding nonmalignant stroma, and this response is associated with tumor growth and an unfavorable outcome. Am J Pathol. 2011 Oct;179(4):1961-8. PMID: 21854754.

Toole BP. Hyaluronan is not just a goo! J Clin Invest. 2000 Aug;106(3):335-6. PMID: 10930435.

" None Not dangerous goods.

LKT T2933 4-Thiouridine 5 mg 44.9 Modified nucleotide used for labeling DNA; DNA crosslinker. Uridine, 4-thio- (8CI)(9CI) Thiouridine 13957-31-8 ≥98% 260.27 C9H12N2O5S C1=CN(C(=O)NC1=S)C2C(C(C(O2)CO)O)O Ambient -20°C water "Wang L, Ruffner DE. An ultraviolet crosslink in the hammerhead ribozyme dependent on 2-thiocytidine or 4-thiouridine substitution. Nucleic Acids Res. 1997 Nov 1;25(21):4355-61. PMID: 9336468.

Ofengand J, Liou R, Kohut J 3rd, et al. Covalent cross-linking of transfer ribonucleic acid to the ribosomal P site. Mechanism and site of reaction in transfer ribonucleic acid. Biochemistry. 1979 Oct 2;18(20):4322-32. PMID: 385051.

" None Not dangerous goods.

LKT T2933 4-Thiouridine 25 mg 109.1 Modified nucleotide used for labeling DNA; DNA crosslinker. Uridine, 4-thio- (8CI)(9CI) Thiouridine 13957-31-8 ≥98% 260.27 C9H12N2O5S C1=CN(C(=O)NC1=S)C2C(C(C(O2)CO)O)O Ambient -20°C water "Wang L, Ruffner DE. An ultraviolet crosslink in the hammerhead ribozyme dependent on 2-thiocytidine or 4-thiouridine substitution. Nucleic Acids Res. 1997 Nov 1;25(21):4355-61. PMID: 9336468.

Ofengand J, Liou R, Kohut J 3rd, et al. Covalent cross-linking of transfer ribonucleic acid to the ribosomal P site. Mechanism and site of reaction in transfer ribonucleic acid. Biochemistry. 1979 Oct 2;18(20):4322-32. PMID: 385051.

" None Not dangerous goods.

LKT T2933 4-Thiouridine 100 mg 352.6 Modified nucleotide used for labeling DNA; DNA crosslinker. Uridine, 4-thio- (8CI)(9CI) Thiouridine 13957-31-8 ≥98% 260.27 C9H12N2O5S C1=CN(C(=O)NC1=S)C2C(C(C(O2)CO)O)O Ambient -20°C water "Wang L, Ruffner DE. An ultraviolet crosslink in the hammerhead ribozyme dependent on 2-thiocytidine or 4-thiouridine substitution. Nucleic Acids Res. 1997 Nov 1;25(21):4355-61. PMID: 9336468.

Ofengand J, Liou R, Kohut J 3rd, et al. Covalent cross-linking of transfer ribonucleic acid to the ribosomal P site. Mechanism and site of reaction in transfer ribonucleic acid. Biochemistry. 1979 Oct 2;18(20):4322-32. PMID: 385051.

" None Not dangerous goods.

LKT T2933 4-Thiouridine 250 mg 713.2 Modified nucleotide used for labeling DNA; DNA crosslinker. Uridine, 4-thio- (8CI)(9CI) Thiouridine 13957-31-8 ≥98% 260.27 C9H12N2O5S C1=CN(C(=O)NC1=S)C2C(C(C(O2)CO)O)O Ambient -20°C water "Wang L, Ruffner DE. An ultraviolet crosslink in the hammerhead ribozyme dependent on 2-thiocytidine or 4-thiouridine substitution. Nucleic Acids Res. 1997 Nov 1;25(21):4355-61. PMID: 9336468.

Ofengand J, Liou R, Kohut J 3rd, et al. Covalent cross-linking of transfer ribonucleic acid to the ribosomal P site. Mechanism and site of reaction in transfer ribonucleic acid. Biochemistry. 1979 Oct 2;18(20):4322-32. PMID: 385051.

" None Not dangerous goods.

LKT H9861 Hypericin 1 mg 197.6 Naphthodianthrone found in Hypericum; dopamine β-hydroxylase and proteasome inhibitor, N-type and P/Q-type Ca2+ channel blocker. 1,3,4,6,8,13-Hexahydroxy-10,11-dimethylphenanthro- [1,10,9,8-opqra]perylene-7,14-dione Hypericum red 548-04-9 ≥97% 504.44 C30H16O8 CC1=CC(=C2C3=C1C4=C5C(=C(C=C4C)O)C(=O)C6=C(C=C(C7=C6C5=C3C8=C7C(=CC(=C8C2=O)O)O)O)O)O Blue Ice 4°C Soluble in DMSO, organic bases or alkaline aqueous solutions. "Chang Y, Wang SJ. Hypericin, the active component of St. John's wort, inhibits glutamate release in the rat cerebrocortical synaptosomes via a mitogen-activated protein kinase-dependent pathway. Eur J Pharmacol. 2010 May 25;634(1-3):53-61. PMID: 20193678.

Galeotti N, Vivoli E, Bilia AR, et al. St. John's Wort reduces neuropathic pain through a hypericin-mediated inhibition of the protein kinase Cgamma and epsilon activity. Biochem Pharmacol. 2010 May 1;79(9):1327-36. PMID: 20045676.

Berlanda J, Kiesslich T, Oberdanner CB, et al. Characterization of apoptosis induced by photodynamic treatment with hypericin in A431 human epidermoid carcinoma cells. J Environ Pathol Toxicol Oncol. 2006;25(1-2):173-88. PMID: 16566716.

Pajonk F, Scholber J, Fiebich B. Hypericin-an inhibitor of proteasome function. Cancer Chemother Pharmacol. 2005 May;55(5):439-46. PMID: 15672261.

Miskovsky P. Hypericin--a new antiviral and antitumor photosensitizer: mechanism of action and interaction with biological macromolecules. Curr Drug Targets. 2002 Feb;3(1):55-84. PMID: 11899265.

" Xn Not dangerous goods.

LKT H9861 Hypericin 5 mg 669.8 Naphthodianthrone found in Hypericum; dopamine β-hydroxylase and proteasome inhibitor, N-type and P/Q-type Ca2+ channel blocker. 1,3,4,6,8,13-Hexahydroxy-10,11-dimethylphenanthro- [1,10,9,8-opqra]perylene-7,14-dione Hypericum red 548-04-9 ≥97% 504.44 C30H16O8 CC1=CC(=C2C3=C1C4=C5C(=C(C=C4C)O)C(=O)C6=C(C=C(C7=C6C5=C3C8=C7C(=CC(=C8C2=O)O)O)O)O)O Blue Ice 4°C Soluble in DMSO, organic bases or alkaline aqueous solutions. "Chang Y, Wang SJ. Hypericin, the active component of St. John's wort, inhibits glutamate release in the rat cerebrocortical synaptosomes via a mitogen-activated protein kinase-dependent pathway. Eur J Pharmacol. 2010 May 25;634(1-3):53-61. PMID: 20193678.

Galeotti N, Vivoli E, Bilia AR, et al. St. John's Wort reduces neuropathic pain through a hypericin-mediated inhibition of the protein kinase Cgamma and epsilon activity. Biochem Pharmacol. 2010 May 1;79(9):1327-36. PMID: 20045676.

Berlanda J, Kiesslich T, Oberdanner CB, et al. Characterization of apoptosis induced by photodynamic treatment with hypericin in A431 human epidermoid carcinoma cells. J Environ Pathol Toxicol Oncol. 2006;25(1-2):173-88. PMID: 16566716.

Pajonk F, Scholber J, Fiebich B. Hypericin-an inhibitor of proteasome function. Cancer Chemother Pharmacol. 2005 May;55(5):439-46. PMID: 15672261.

Miskovsky P. Hypericin--a new antiviral and antitumor photosensitizer: mechanism of action and interaction with biological macromolecules. Curr Drug Targets. 2002 Feb;3(1):55-84. PMID: 11899265.

" Xn Not dangerous goods.

LKT T2932 Thiamphenicol Glycinate Hydrochloride 1 g 47.6 Chloramphenicol derivative; protein translation inhibitor, peptidyl transferase inhibitor. 2,2-dichloro-N-[(1R,2R)-2-hydroxy-1-hydroxymethyl- 2-[4-methylsulphonyl)phenyl]ethyl]acetamide glycinate hydrochloride Neomyson G HCl; Urfamicin HCl 2611-61-2 ≥98% 449.7 C14H18Cl2N2O6S HCl CS(=O)(=O)C1=CC=C(C=C1)C(C(COC(=O)CN)NC(=O)C(Cl)Cl)O.Cl Ambient Ambient Soluble in water and DMF. "Raymond J, Boutros N, Bergeret M. Role of thiamphenicol in the treatment of community-acquired lung infections. Med Trop (Mars). 2004;64(1):33-8. PMID: 15224555.

Marchese A, Debbia EA, Tonoli E, et al. In vitro activity of thiamphenicol against multiresistant Streptococcus pneumoniae, Haemophilus influenzae and Staphylococcus aureus in Italy. J Chemother. 2002 Dec;14(6):554-61. PMID: 12583545.

" Not dangerous goods.

LKT T2932 Thiamphenicol Glycinate Hydrochloride 5 g 136 Chloramphenicol derivative; protein translation inhibitor, peptidyl transferase inhibitor. 2,2-dichloro-N-[(1R,2R)-2-hydroxy-1-hydroxymethyl- 2-[4-methylsulphonyl)phenyl]ethyl]acetamide glycinate hydrochloride Neomyson G HCl; Urfamicin HCl 2611-61-2 ≥98% 449.7 C14H18Cl2N2O6S HCl CS(=O)(=O)C1=CC=C(C=C1)C(C(COC(=O)CN)NC(=O)C(Cl)Cl)O.Cl Ambient Ambient Soluble in water and DMF. "Raymond J, Boutros N, Bergeret M. Role of thiamphenicol in the treatment of community-acquired lung infections. Med Trop (Mars). 2004;64(1):33-8. PMID: 15224555.

Marchese A, Debbia EA, Tonoli E, et al. In vitro activity of thiamphenicol against multiresistant Streptococcus pneumoniae, Haemophilus influenzae and Staphylococcus aureus in Italy. J Chemother. 2002 Dec;14(6):554-61. PMID: 12583545.

" Not dangerous goods.

LKT T2932 Thiamphenicol Glycinate Hydrochloride 25 g 305.9 Chloramphenicol derivative; protein translation inhibitor, peptidyl transferase inhibitor. 2,2-dichloro-N-[(1R,2R)-2-hydroxy-1-hydroxymethyl- 2-[4-methylsulphonyl)phenyl]ethyl]acetamide glycinate hydrochloride Neomyson G HCl; Urfamicin HCl 2611-61-2 ≥98% 449.7 C14H18Cl2N2O6S HCl CS(=O)(=O)C1=CC=C(C=C1)C(C(COC(=O)CN)NC(=O)C(Cl)Cl)O.Cl Ambient Ambient Soluble in water and DMF. "Raymond J, Boutros N, Bergeret M. Role of thiamphenicol in the treatment of community-acquired lung infections. Med Trop (Mars). 2004;64(1):33-8. PMID: 15224555.

Marchese A, Debbia EA, Tonoli E, et al. In vitro activity of thiamphenicol against multiresistant Streptococcus pneumoniae, Haemophilus influenzae and Staphylococcus aureus in Italy. J Chemother. 2002 Dec;14(6):554-61. PMID: 12583545.

" Not dangerous goods.

LKT T2930 Thiabendazole 10 g 52.6 Benzimidazole; microtubule polymerization inhibitor. "2-(4-Thiazolyl)-1H-benzimidazole 

" MK-360; Thibenzole; Equizole; Mertect; Storite; TBZ; Tecto. 148-79-8 ≥98% 201.25 C10H7N3S C1=CC=C2C(=C1)NC(=N2)C3=CSC=N3 Stable at room temperature. Incompatible with strong oxidizing agents, and strong bases. Ambient Ambient Soluble in DMF and DMSO. Slightly soluble in alcohols and esters. "Zhang J, Zhao C, Gao Y, et al. Thiabendazole, a well-known antifungal drug, exhibits anti-metastatic melanoma B16F10 activity via inhibiting VEGF expression and inducing apoptosis. Pharmazie. 2013 Dec;68(12):962-8. PMID: 24400443.

Satou T, Koga M, Koike K, et al. Nematocidal activities of thiabendazole and ivermectin against the larvae of Strongyloides ratti and S. venezuelensis. Vet Parasitol. 2001 Aug 31;99(4):311-22. PMID: 11511418.

Crebelli R, Conti G, Conti L, et al. In vitro studies with nine known or suspected spindle poisons: results in tests for chromosome malsegregation in Aspergillus nidulans. Mutagenesis. 1991 Mar;6(2):131-6. PMID: 2056914.

Lubega GW, Prichard RK. Specific interaction of benzimidazole anthelmintics with tubulin: high-affinity binding and benzimidazole resistance in Haemonchus contortus. Mol Biochem Parasitol. 1990 Jan 15;38(2):221-32. PMID: 2325707.

" N "UN number: 3077     Class: 9     Packing Group: III

Proper shipping name: Environmentally hazardous substance, solid, n.o.s. (Thiabendazole)"

LKT T2930 Thiabendazole 100 g 103 Benzimidazole; microtubule polymerization inhibitor. "2-(4-Thiazolyl)-1H-benzimidazole 

" MK-360; Thibenzole; Equizole; Mertect; Storite; TBZ; Tecto. 148-79-8 ≥98% 201.25 C10H7N3S C1=CC=C2C(=C1)NC(=N2)C3=CSC=N3 Stable at room temperature. Incompatible with strong oxidizing agents, and strong bases. Ambient Ambient Soluble in DMF and DMSO. Slightly soluble in alcohols and esters. "Zhang J, Zhao C, Gao Y, et al. Thiabendazole, a well-known antifungal drug, exhibits anti-metastatic melanoma B16F10 activity via inhibiting VEGF expression and inducing apoptosis. Pharmazie. 2013 Dec;68(12):962-8. PMID: 24400443.

Satou T, Koga M, Koike K, et al. Nematocidal activities of thiabendazole and ivermectin against the larvae of Strongyloides ratti and S. venezuelensis. Vet Parasitol. 2001 Aug 31;99(4):311-22. PMID: 11511418.

Crebelli R, Conti G, Conti L, et al. In vitro studies with nine known or suspected spindle poisons: results in tests for chromosome malsegregation in Aspergillus nidulans. Mutagenesis. 1991 Mar;6(2):131-6. PMID: 2056914.

Lubega GW, Prichard RK. Specific interaction of benzimidazole anthelmintics with tubulin: high-affinity binding and benzimidazole resistance in Haemonchus contortus. Mol Biochem Parasitol. 1990 Jan 15;38(2):221-32. PMID: 2325707.

" N "UN number: 3077     Class: 9     Packing Group: III

Proper shipping name: Environmentally hazardous substance, solid, n.o.s. (Thiabendazole)"

LKT T2930 Thiabendazole 500 g 373.8 Benzimidazole; microtubule polymerization inhibitor. "2-(4-Thiazolyl)-1H-benzimidazole 

" MK-360; Thibenzole; Equizole; Mertect; Storite; TBZ; Tecto. 148-79-8 ≥98% 201.25 C10H7N3S C1=CC=C2C(=C1)NC(=N2)C3=CSC=N3 Stable at room temperature. Incompatible with strong oxidizing agents, and strong bases. Ambient Ambient Soluble in DMF and DMSO. Slightly soluble in alcohols and esters. "Zhang J, Zhao C, Gao Y, et al. Thiabendazole, a well-known antifungal drug, exhibits anti-metastatic melanoma B16F10 activity via inhibiting VEGF expression and inducing apoptosis. Pharmazie. 2013 Dec;68(12):962-8. PMID: 24400443.

Satou T, Koga M, Koike K, et al. Nematocidal activities of thiabendazole and ivermectin against the larvae of Strongyloides ratti and S. venezuelensis. Vet Parasitol. 2001 Aug 31;99(4):311-22. PMID: 11511418.

Crebelli R, Conti G, Conti L, et al. In vitro studies with nine known or suspected spindle poisons: results in tests for chromosome malsegregation in Aspergillus nidulans. Mutagenesis. 1991 Mar;6(2):131-6. PMID: 2056914.

Lubega GW, Prichard RK. Specific interaction of benzimidazole anthelmintics with tubulin: high-affinity binding and benzimidazole resistance in Haemonchus contortus. Mol Biochem Parasitol. 1990 Jan 15;38(2):221-32. PMID: 2325707.

" N "UN number: 3077     Class: 9     Packing Group: III

Proper shipping name: Environmentally hazardous substance, solid, n.o.s. (Thiabendazole)"

LKT T2835 6-Thioguanine 250 mg 52.6 Nucleotide (guanine) analog, prevents guanine synthesis; DNA replication inhibitor. tioguanine, thioguanine 154-42-7 ≥90% 167.19 C5H5N5S C1=NC2=C(N1)C(=S)N=C(N2)N Ambient Ambient Soluble in NaOH (50 mg/ml), slightly soluble in ethanol, insoluble in water "Zhang F, Fu L, Wang Y. 6-thioguanine induces mitochondrial dysfunction and oxidative DNA damage in acute lymphoblastic leukemia cells. Mol Cell Proteomics. 2013 Dec;12(12):3803-11. PMID: 24043426.

Bohon J, de los Santos CR. Effect of 6-thioguanine on the stability of duplex DNA. Nucleic Acids Res. 2005 May 19;33(9):2880-6. PMID: 15905476.

Thomas CW, Myhre GM, Tschumper R, et al. Selective inhibition of inflammatory gene expression in activated T lymphocytes: a mechanism of immune suppression by thiopurines. J Pharmacol Exp Ther. 2005 Feb;312(2):537-45. PMID: 15388785.

Pfefferkorn ER, Bzik DJ, Honsinger CP. Toxoplasma gondii: mechanism of the parasitostatic action of 6-thioxanthine. Exp Parasitol. 2001 Dec;99(4):235-43. PMID: 11888251.

Morgan CJ, Chawdry RN, Smith AR, et al. 6-Thioguanine-induced growth arrest in 6-mercaptopurine-resistant human leukemia cells. Cancer Res. 1994 Oct 15;54(20):5387-93. PMID: 7923170.

" T "UN number: 2811     Class: 6.1     Packing Group: III

Proper shipping name: Toxic solid, organic, n.o.s. (6-Thioguanine)"

LKT T2835 6-Thioguanine 500 mg 84.3 Nucleotide (guanine) analog, prevents guanine synthesis; DNA replication inhibitor. tioguanine, thioguanine 154-42-7 ≥90% 167.19 C5H5N5S C1=NC2=C(N1)C(=S)N=C(N2)N Ambient Ambient Soluble in NaOH (50 mg/ml), slightly soluble in ethanol, insoluble in water "Zhang F, Fu L, Wang Y. 6-thioguanine induces mitochondrial dysfunction and oxidative DNA damage in acute lymphoblastic leukemia cells. Mol Cell Proteomics. 2013 Dec;12(12):3803-11. PMID: 24043426.

Bohon J, de los Santos CR. Effect of 6-thioguanine on the stability of duplex DNA. Nucleic Acids Res. 2005 May 19;33(9):2880-6. PMID: 15905476.

Thomas CW, Myhre GM, Tschumper R, et al. Selective inhibition of inflammatory gene expression in activated T lymphocytes: a mechanism of immune suppression by thiopurines. J Pharmacol Exp Ther. 2005 Feb;312(2):537-45. PMID: 15388785.

Pfefferkorn ER, Bzik DJ, Honsinger CP. Toxoplasma gondii: mechanism of the parasitostatic action of 6-thioxanthine. Exp Parasitol. 2001 Dec;99(4):235-43. PMID: 11888251.

Morgan CJ, Chawdry RN, Smith AR, et al. 6-Thioguanine-induced growth arrest in 6-mercaptopurine-resistant human leukemia cells. Cancer Res. 1994 Oct 15;54(20):5387-93. PMID: 7923170.

" T "UN number: 2811     Class: 6.1     Packing Group: III

Proper shipping name: Toxic solid, organic, n.o.s. (6-Thioguanine)"

LKT T2835 6-Thioguanine 1 g 131.4 Nucleotide (guanine) analog, prevents guanine synthesis; DNA replication inhibitor. tioguanine, thioguanine 154-42-7 ≥90% 167.19 C5H5N5S C1=NC2=C(N1)C(=S)N=C(N2)N Ambient Ambient Soluble in NaOH (50 mg/ml), slightly soluble in ethanol, insoluble in water "Zhang F, Fu L, Wang Y. 6-thioguanine induces mitochondrial dysfunction and oxidative DNA damage in acute lymphoblastic leukemia cells. Mol Cell Proteomics. 2013 Dec;12(12):3803-11. PMID: 24043426.

Bohon J, de los Santos CR. Effect of 6-thioguanine on the stability of duplex DNA. Nucleic Acids Res. 2005 May 19;33(9):2880-6. PMID: 15905476.

Thomas CW, Myhre GM, Tschumper R, et al. Selective inhibition of inflammatory gene expression in activated T lymphocytes: a mechanism of immune suppression by thiopurines. J Pharmacol Exp Ther. 2005 Feb;312(2):537-45. PMID: 15388785.

Pfefferkorn ER, Bzik DJ, Honsinger CP. Toxoplasma gondii: mechanism of the parasitostatic action of 6-thioxanthine. Exp Parasitol. 2001 Dec;99(4):235-43. PMID: 11888251.

Morgan CJ, Chawdry RN, Smith AR, et al. 6-Thioguanine-induced growth arrest in 6-mercaptopurine-resistant human leukemia cells. Cancer Res. 1994 Oct 15;54(20):5387-93. PMID: 7923170.

" T "UN number: 2811     Class: 6.1     Packing Group: III

Proper shipping name: Toxic solid, organic, n.o.s. (6-Thioguanine)"

LKT I0418 Iberverin 25 mg 119.9 ITC found in cruciferous vegetables, homolog of sulforaphane. 1-Isothiocyanato-3-(methylsulfenyl)-propane 1-Isothiocyanato-3-(methylthio)propane;  3-Methyl- mercaptopropyl isothiocyanate; 3-Methylthiopropyl  isothiocyanate 505-79-3 ≥98% 147.26 C5H9NS2 CSCCCN=C=S Ambient -20°C "Ernst IM, Palani K, Esatbeyoglu T, et al. Synthesis and Nrf2-inducing activity of the isothiocyanates iberverin, iberin and cheirolin. Pharmacol Res. 2013 Apr;70(1):155-62. PMID: 23403058.

Kim SH, Singh SV. D,L-Sulforaphane causes transcriptional repression of androgen receptor in human prostate cancer cells. Mol Cancer Ther. 2009 Jul;8(7):1946-54. PMID: 19584240.

Munday R, Munday CM. Induction of phase II detoxification enzymes in rats by plant-derived isothiocyanates: comparison of allyl isothiocyanate with sulforaphane and related compounds. J Agric Food Chem. 2004 Apr 7;52(7):1867-71. PMID: 15053522.

" T "UN number: 2922     Class: 8 (6.1)     Packing Group: II

Proper shipping name: Corrosive liquid, toxic, n.o.s. (Iberverin)"

LKT I0418 Iberverin 50 mg 207.3 ITC found in cruciferous vegetables, homolog of sulforaphane. 1-Isothiocyanato-3-(methylsulfenyl)-propane 1-Isothiocyanato-3-(methylthio)propane;  3-Methyl- mercaptopropyl isothiocyanate; 3-Methylthiopropyl  isothiocyanate 505-79-3 ≥98% 147.26 C5H9NS2 CSCCCN=C=S Ambient -20°C "Ernst IM, Palani K, Esatbeyoglu T, et al. Synthesis and Nrf2-inducing activity of the isothiocyanates iberverin, iberin and cheirolin. Pharmacol Res. 2013 Apr;70(1):155-62. PMID: 23403058.

Kim SH, Singh SV. D,L-Sulforaphane causes transcriptional repression of androgen receptor in human prostate cancer cells. Mol Cancer Ther. 2009 Jul;8(7):1946-54. PMID: 19584240.

Munday R, Munday CM. Induction of phase II detoxification enzymes in rats by plant-derived isothiocyanates: comparison of allyl isothiocyanate with sulforaphane and related compounds. J Agric Food Chem. 2004 Apr 7;52(7):1867-71. PMID: 15053522.

" T "UN number: 2922     Class: 8 (6.1)     Packing Group: II

Proper shipping name: Corrosive liquid, toxic, n.o.s. (Iberverin)"

LKT I0418 Iberverin 100 mg 359.1 ITC found in cruciferous vegetables, homolog of sulforaphane. 1-Isothiocyanato-3-(methylsulfenyl)-propane 1-Isothiocyanato-3-(methylthio)propane;  3-Methyl- mercaptopropyl isothiocyanate; 3-Methylthiopropyl  isothiocyanate 505-79-3 ≥98% 147.26 C5H9NS2 CSCCCN=C=S Ambient -20°C "Ernst IM, Palani K, Esatbeyoglu T, et al. Synthesis and Nrf2-inducing activity of the isothiocyanates iberverin, iberin and cheirolin. Pharmacol Res. 2013 Apr;70(1):155-62. PMID: 23403058.

Kim SH, Singh SV. D,L-Sulforaphane causes transcriptional repression of androgen receptor in human prostate cancer cells. Mol Cancer Ther. 2009 Jul;8(7):1946-54. PMID: 19584240.

Munday R, Munday CM. Induction of phase II detoxification enzymes in rats by plant-derived isothiocyanates: comparison of allyl isothiocyanate with sulforaphane and related compounds. J Agric Food Chem. 2004 Apr 7;52(7):1867-71. PMID: 15053522.

" T "UN number: 2922     Class: 8 (6.1)     Packing Group: II

Proper shipping name: Corrosive liquid, toxic, n.o.s. (Iberverin)"

LKT I0418 Iberverin 500 mg 1213.4 ITC found in cruciferous vegetables, homolog of sulforaphane. 1-Isothiocyanato-3-(methylsulfenyl)-propane 1-Isothiocyanato-3-(methylthio)propane;  3-Methyl- mercaptopropyl isothiocyanate; 3-Methylthiopropyl  isothiocyanate 505-79-3 ≥98% 147.26 C5H9NS2 CSCCCN=C=S Ambient -20°C "Ernst IM, Palani K, Esatbeyoglu T, et al. Synthesis and Nrf2-inducing activity of the isothiocyanates iberverin, iberin and cheirolin. Pharmacol Res. 2013 Apr;70(1):155-62. PMID: 23403058.

Kim SH, Singh SV. D,L-Sulforaphane causes transcriptional repression of androgen receptor in human prostate cancer cells. Mol Cancer Ther. 2009 Jul;8(7):1946-54. PMID: 19584240.

Munday R, Munday CM. Induction of phase II detoxification enzymes in rats by plant-derived isothiocyanates: comparison of allyl isothiocyanate with sulforaphane and related compounds. J Agric Food Chem. 2004 Apr 7;52(7):1867-71. PMID: 15053522.

" T "UN number: 2922     Class: 8 (6.1)     Packing Group: II

Proper shipping name: Corrosive liquid, toxic, n.o.s. (Iberverin)"

LKT I0480 Ibudilast 10 mg 121.9 PDE3/5 inhibitor, LTD4 antagonist. 3-Isobutyryl-2-isopropylpyrazolo[1,5-a]pyridine; 2-Methyl-1-[2-(1-methylethyl)pyrazolo[1,5-a]pyridin-3-yl]-1-propanone; 2-Isopropyl-3-isobutyrylpyrazolo[1,5-a]pyridine; KC-404, AV-411 50847-11-5 ≥98% 230.31 C14H18N2O CC(C)C1=NN2C=CC=CC2=C1C(=O)C(C)C Ambient Ambient "Inoue N, Fukuda S, Inada T, et al. Effect of ibudilast on the reciprocal inhibitory visual-vestibular interaction closely related to dizziness after cerebral ischemia. J Stroke Cerebrovasc Dis. 2014 Jan;23(1):51-5. PMID: 23085301.

Kiebala M, Maggirwar SB. Ibudilast, a pharmacologic phosphodiesterase inhibitor, prevents human immunodeficiency virus-1 Tat-mediated activation of microglial cells. PLoS One. 2011 Apr 8;6(4):e18633. PMID: 21494611.

Cho Y, Crichlow GV, Vermeire JJ, et al. Allosteric inhibition of macrophage migration inhibitory factor revealed by ibudilast. Proc Natl Acad Sci U S A. 2010 Jun 22;107(25):11313-8. PMID: 20534506.

Ledeboer A, Hutchinson MR, Watkins LR, et al. Ibudilast (AV-411). A new class therapeutic candidate for neuropathic pain and opioid withdrawal syndromes. Expert Opin Investig Drugs. 2007 Jul;16(7):935-50. PMID: 17594181.

Kishi Y, Ohta S, Kasuya N, et al. Ibudilast modulates platelet-endothelium interaction mainly through cyclic GMP-dependent mechanism. J Cardiovasc Pharmacol. 2000 Jul;36(1):65-70. PMID: 10892662.

Ohashi M, Kanai R, Nishino K, et al. Antagonistic effect of KC-404, a new anti-asthmatic agent, on leukotriene D4-induced contractile responses in isolated guinea pig smooth muscles. Prostaglandins. 1986 Dec;32(6):875-88. PMID: 3562868.

Ohashi M, Ohkubo H, Kito J, et al. A new vasodilator 3-isobutyryl-2-isopropylpyrazolo[1,5-a]pyridine (KC-404) has a dual mechanism of action on platelet aggregation. Arch Int Pharmacodyn Ther. 1986 Oct;283(2):321-34. PMID: 3024600.

" Xn Not dangerous goods.

LKT I0480 Ibudilast 25 mg 281.2 PDE3/5 inhibitor, LTD4 antagonist. 3-Isobutyryl-2-isopropylpyrazolo[1,5-a]pyridine; 2-Methyl-1-[2-(1-methylethyl)pyrazolo[1,5-a]pyridin-3-yl]-1-propanone; 2-Isopropyl-3-isobutyrylpyrazolo[1,5-a]pyridine; KC-404, AV-411 50847-11-5 ≥98% 230.31 C14H18N2O CC(C)C1=NN2C=CC=CC2=C1C(=O)C(C)C Ambient Ambient "Inoue N, Fukuda S, Inada T, et al. Effect of ibudilast on the reciprocal inhibitory visual-vestibular interaction closely related to dizziness after cerebral ischemia. J Stroke Cerebrovasc Dis. 2014 Jan;23(1):51-5. PMID: 23085301.

Kiebala M, Maggirwar SB. Ibudilast, a pharmacologic phosphodiesterase inhibitor, prevents human immunodeficiency virus-1 Tat-mediated activation of microglial cells. PLoS One. 2011 Apr 8;6(4):e18633. PMID: 21494611.

Cho Y, Crichlow GV, Vermeire JJ, et al. Allosteric inhibition of macrophage migration inhibitory factor revealed by ibudilast. Proc Natl Acad Sci U S A. 2010 Jun 22;107(25):11313-8. PMID: 20534506.

Ledeboer A, Hutchinson MR, Watkins LR, et al. Ibudilast (AV-411). A new class therapeutic candidate for neuropathic pain and opioid withdrawal syndromes. Expert Opin Investig Drugs. 2007 Jul;16(7):935-50. PMID: 17594181.

Kishi Y, Ohta S, Kasuya N, et al. Ibudilast modulates platelet-endothelium interaction mainly through cyclic GMP-dependent mechanism. J Cardiovasc Pharmacol. 2000 Jul;36(1):65-70. PMID: 10892662.

Ohashi M, Kanai R, Nishino K, et al. Antagonistic effect of KC-404, a new anti-asthmatic agent, on leukotriene D4-induced contractile responses in isolated guinea pig smooth muscles. Prostaglandins. 1986 Dec;32(6):875-88. PMID: 3562868.

Ohashi M, Ohkubo H, Kito J, et al. A new vasodilator 3-isobutyryl-2-isopropylpyrazolo[1,5-a]pyridine (KC-404) has a dual mechanism of action on platelet aggregation. Arch Int Pharmacodyn Ther. 1986 Oct;283(2):321-34. PMID: 3024600.

" Xn Not dangerous goods.

LKT I0480 Ibudilast 100 mg 937.5 PDE3/5 inhibitor, LTD4 antagonist. 3-Isobutyryl-2-isopropylpyrazolo[1,5-a]pyridine; 2-Methyl-1-[2-(1-methylethyl)pyrazolo[1,5-a]pyridin-3-yl]-1-propanone; 2-Isopropyl-3-isobutyrylpyrazolo[1,5-a]pyridine; KC-404, AV-411 50847-11-5 ≥98% 230.31 C14H18N2O CC(C)C1=NN2C=CC=CC2=C1C(=O)C(C)C Ambient Ambient "Inoue N, Fukuda S, Inada T, et al. Effect of ibudilast on the reciprocal inhibitory visual-vestibular interaction closely related to dizziness after cerebral ischemia. J Stroke Cerebrovasc Dis. 2014 Jan;23(1):51-5. PMID: 23085301.

Kiebala M, Maggirwar SB. Ibudilast, a pharmacologic phosphodiesterase inhibitor, prevents human immunodeficiency virus-1 Tat-mediated activation of microglial cells. PLoS One. 2011 Apr 8;6(4):e18633. PMID: 21494611.

Cho Y, Crichlow GV, Vermeire JJ, et al. Allosteric inhibition of macrophage migration inhibitory factor revealed by ibudilast. Proc Natl Acad Sci U S A. 2010 Jun 22;107(25):11313-8. PMID: 20534506.

Ledeboer A, Hutchinson MR, Watkins LR, et al. Ibudilast (AV-411). A new class therapeutic candidate for neuropathic pain and opioid withdrawal syndromes. Expert Opin Investig Drugs. 2007 Jul;16(7):935-50. PMID: 17594181.

Kishi Y, Ohta S, Kasuya N, et al. Ibudilast modulates platelet-endothelium interaction mainly through cyclic GMP-dependent mechanism. J Cardiovasc Pharmacol. 2000 Jul;36(1):65-70. PMID: 10892662.

Ohashi M, Kanai R, Nishino K, et al. Antagonistic effect of KC-404, a new anti-asthmatic agent, on leukotriene D4-induced contractile responses in isolated guinea pig smooth muscles. Prostaglandins. 1986 Dec;32(6):875-88. PMID: 3562868.

Ohashi M, Ohkubo H, Kito J, et al. A new vasodilator 3-isobutyryl-2-isopropylpyrazolo[1,5-a]pyridine (KC-404) has a dual mechanism of action on platelet aggregation. Arch Int Pharmacodyn Ther. 1986 Oct;283(2):321-34. PMID: 3024600.

" Xn Not dangerous goods.

LKT T2834 Thiolutin 1 mg 58.2 Dithiolopyrrolone; RNA polymerase inhibitor. 87-11-6 ≥98% 228.29 C8H8N2O2S2 CC(=O)NC1=C2C(=CSS2)N(C1=O)C Ambient 4°C Dichloromethane or Methanol, DMSO "Qin Z, Huang S, Yu Y, et al. Dithiolopyrrolone natural products: isolation, synthesis and biosynthesis. Mar Drugs. 2013 Oct 17;11(10):3970-97. PMID: 24141227.

Jia Y, Wu SL, Isenberg JS, et al. Thiolutin inhibits endothelial cell adhesion by perturbing Hsp27 interactions with components of the actin and intermediate filament cytoskeleton. Cell Stress Chaperones. 2010 Mar;15(2):165-81. PMID: 19579057.

Pelechano V, Pérez-Ortín JE. The transcriptional inhibitor thiolutin blocks mRNA degradation in yeast. Yeast. 2008 Feb;25(2):85-92. PMID: 17914747.

Minamiguchi K, Kumagai H, Masuda T, et al. Thiolutin, an inhibitor of HUVEC adhesion to vitronectin, reduces paxillin in HUVECs and suppresses tumor cell-induced angiogenesis. Int J Cancer. 2001 Aug 1;93(3):307-16. PMID: 11433393.

Tipper DJ. Inhibition of yeast ribonucleic acid polymerases by thiolutin. J Bacteriol. 1973 Oct;116(1):245-56. PMID: 4583213.

" T+ "UN number: 2811     Class:  6.1     Packing group:  II

Proper shipping name:  Toxic solid, organic, n.o.s. (N-(4,5-Dihydro-4-methyl-5-oxo-1,2-dithiolo[4,3-b]pyrrol-6-yl))

Poison inhalation hazard:  No"

LKT I0481 Ibuprofen 1 g 27.2 NSAID; COX-1/2 inhibitor. α-Methyl-4-(2-methylpropyl)benzeneacetic acid Advil 15687-27-1 ≥98% 206.28 C13H18O2 CC(C)CC1=CC=C(C=C1)C(C)C(=O)O Ambient Ambient Insoluble in water.  Soluble in most organic solvents. "Vlad SC, Miller DR, Kowall NW, et al. Protective effects of NSAIDs on the development of Alzheimer disease. Neurology. 2008 May 6;70(19):1672-7. PMID: 18458226.

Van Esch A, Van Steensel-Moll HA, Steyerberg EW, et al. Antipyretic efficacy of ibuprofen and acetaminophen in children with febrile seizures. Arch Pediatr Adolesc Med. 1995 Jun;149(6):632-7. PMID: 7767417.

Li W, Li J, Ashok M, et al. A cardiovascular drug rescues mice from lethal sepsis by selectively attentuating a late-acting proinflammatory mediator, high mobility group box 1. J Immunol. 2007 Mar 15;178(6):3856-3864. PMID: 17339485.

" Xn Not dangerous goods.

LKT I0481 Ibuprofen 5 g 97.8 NSAID; COX-1/2 inhibitor. α-Methyl-4-(2-methylpropyl)benzeneacetic acid Advil 15687-27-1 ≥98% 206.28 C13H18O2 CC(C)CC1=CC=C(C=C1)C(C)C(=O)O Ambient Ambient Insoluble in water.  Soluble in most organic solvents. "Vlad SC, Miller DR, Kowall NW, et al. Protective effects of NSAIDs on the development of Alzheimer disease. Neurology. 2008 May 6;70(19):1672-7. PMID: 18458226.

Van Esch A, Van Steensel-Moll HA, Steyerberg EW, et al. Antipyretic efficacy of ibuprofen and acetaminophen in children with febrile seizures. Arch Pediatr Adolesc Med. 1995 Jun;149(6):632-7. PMID: 7767417.

Li W, Li J, Ashok M, et al. A cardiovascular drug rescues mice from lethal sepsis by selectively attentuating a late-acting proinflammatory mediator, high mobility group box 1. J Immunol. 2007 Mar 15;178(6):3856-3864. PMID: 17339485.

" Xn Not dangerous goods.

LKT I0481 Ibuprofen 10 g 176.2 NSAID; COX-1/2 inhibitor. α-Methyl-4-(2-methylpropyl)benzeneacetic acid Advil 15687-27-1 ≥98% 206.28 C13H18O2 CC(C)CC1=CC=C(C=C1)C(C)C(=O)O Ambient Ambient Insoluble in water.  Soluble in most organic solvents. "Vlad SC, Miller DR, Kowall NW, et al. Protective effects of NSAIDs on the development of Alzheimer disease. Neurology. 2008 May 6;70(19):1672-7. PMID: 18458226.

Van Esch A, Van Steensel-Moll HA, Steyerberg EW, et al. Antipyretic efficacy of ibuprofen and acetaminophen in children with febrile seizures. Arch Pediatr Adolesc Med. 1995 Jun;149(6):632-7. PMID: 7767417.

Li W, Li J, Ashok M, et al. A cardiovascular drug rescues mice from lethal sepsis by selectively attentuating a late-acting proinflammatory mediator, high mobility group box 1. J Immunol. 2007 Mar 15;178(6):3856-3864. PMID: 17339485.

" Xn Not dangerous goods.

LKT T2834 Thiolutin 5 mg 191.6 Dithiolopyrrolone; RNA polymerase inhibitor. 87-11-6 ≥98% 228.29 C8H8N2O2S2 CC(=O)NC1=C2C(=CSS2)N(C1=O)C Ambient 4°C Dichloromethane or Methanol, DMSO "Qin Z, Huang S, Yu Y, et al. Dithiolopyrrolone natural products: isolation, synthesis and biosynthesis. Mar Drugs. 2013 Oct 17;11(10):3970-97. PMID: 24141227.

Jia Y, Wu SL, Isenberg JS, et al. Thiolutin inhibits endothelial cell adhesion by perturbing Hsp27 interactions with components of the actin and intermediate filament cytoskeleton. Cell Stress Chaperones. 2010 Mar;15(2):165-81. PMID: 19579057.

Pelechano V, Pérez-Ortín JE. The transcriptional inhibitor thiolutin blocks mRNA degradation in yeast. Yeast. 2008 Feb;25(2):85-92. PMID: 17914747.

Minamiguchi K, Kumagai H, Masuda T, et al. Thiolutin, an inhibitor of HUVEC adhesion to vitronectin, reduces paxillin in HUVECs and suppresses tumor cell-induced angiogenesis. Int J Cancer. 2001 Aug 1;93(3):307-16. PMID: 11433393.

Tipper DJ. Inhibition of yeast ribonucleic acid polymerases by thiolutin. J Bacteriol. 1973 Oct;116(1):245-56. PMID: 4583213.

" T+ "UN number: 2811     Class:  6.1     Packing group:  II

Proper shipping name:  Toxic solid, organic, n.o.s. (N-(4,5-Dihydro-4-methyl-5-oxo-1,2-dithiolo[4,3-b]pyrrol-6-yl))

Poison inhalation hazard:  No"

LKT T2834 Thiolutin 10 mg 337.3 Dithiolopyrrolone; RNA polymerase inhibitor. 87-11-6 ≥98% 228.29 C8H8N2O2S2 CC(=O)NC1=C2C(=CSS2)N(C1=O)C Ambient 4°C Dichloromethane or Methanol, DMSO "Qin Z, Huang S, Yu Y, et al. Dithiolopyrrolone natural products: isolation, synthesis and biosynthesis. Mar Drugs. 2013 Oct 17;11(10):3970-97. PMID: 24141227.

Jia Y, Wu SL, Isenberg JS, et al. Thiolutin inhibits endothelial cell adhesion by perturbing Hsp27 interactions with components of the actin and intermediate filament cytoskeleton. Cell Stress Chaperones. 2010 Mar;15(2):165-81. PMID: 19579057.

Pelechano V, Pérez-Ortín JE. The transcriptional inhibitor thiolutin blocks mRNA degradation in yeast. Yeast. 2008 Feb;25(2):85-92. PMID: 17914747.

Minamiguchi K, Kumagai H, Masuda T, et al. Thiolutin, an inhibitor of HUVEC adhesion to vitronectin, reduces paxillin in HUVECs and suppresses tumor cell-induced angiogenesis. Int J Cancer. 2001 Aug 1;93(3):307-16. PMID: 11433393.

Tipper DJ. Inhibition of yeast ribonucleic acid polymerases by thiolutin. J Bacteriol. 1973 Oct;116(1):245-56. PMID: 4583213.

" T+ "UN number: 2811     Class:  6.1     Packing group:  II

Proper shipping name:  Toxic solid, organic, n.o.s. (N-(4,5-Dihydro-4-methyl-5-oxo-1,2-dithiolo[4,3-b]pyrrol-6-yl))

Poison inhalation hazard:  No"

LKT I0482 S-(+)-Ibuprofen 1 g 47.6 Optically active isomer of ibuprofen, NSAID; COX-1/2 inhibitor. (+)-2-(4-Isobutylphenyl)-propionic Acid 51146-56-6 ≥98% 206.28 C13H18O2 CC(C)CC1=CC=C(C=C1)C(C)C(=O)O Protect from light. Ambient Ambient Soluble in methanol, DMSO and ethanol. "Vlad SC, Miller DR, Kowall NW, et al. Protective effects of NSAIDs on the development of Alzheimer disease. Neurology. 2008 May 6;70(19):1672-7. PMID: 18458226.

Van Esch A, Van Steensel-Moll HA, Steyerberg EW, et al. Antipyretic efficacy of ibuprofen and acetaminophen in children with febrile seizures. Arch Pediatr Adolesc Med. 1995 Jun;149(6):632-7. PMID: 7767417.

" None Not dangerous goods.

LKT I0482 S-(+)-Ibuprofen 5 g 169.9 Optically active isomer of ibuprofen, NSAID; COX-1/2 inhibitor. (+)-2-(4-Isobutylphenyl)-propionic Acid 51146-56-6 ≥98% 206.28 C13H18O2 CC(C)CC1=CC=C(C=C1)C(C)C(=O)O Protect from light. Ambient Ambient Soluble in methanol, DMSO and ethanol. "Vlad SC, Miller DR, Kowall NW, et al. Protective effects of NSAIDs on the development of Alzheimer disease. Neurology. 2008 May 6;70(19):1672-7. PMID: 18458226.

Van Esch A, Van Steensel-Moll HA, Steyerberg EW, et al. Antipyretic efficacy of ibuprofen and acetaminophen in children with febrile seizures. Arch Pediatr Adolesc Med. 1995 Jun;149(6):632-7. PMID: 7767417.

" None Not dangerous goods.

LKT I0482 S-(+)-Ibuprofen 25 g 543.6 Optically active isomer of ibuprofen, NSAID; COX-1/2 inhibitor. (+)-2-(4-Isobutylphenyl)-propionic Acid 51146-56-6 ≥98% 206.28 C13H18O2 CC(C)CC1=CC=C(C=C1)C(C)C(=O)O Protect from light. Ambient Ambient Soluble in methanol, DMSO and ethanol. "Vlad SC, Miller DR, Kowall NW, et al. Protective effects of NSAIDs on the development of Alzheimer disease. Neurology. 2008 May 6;70(19):1672-7. PMID: 18458226.

Van Esch A, Van Steensel-Moll HA, Steyerberg EW, et al. Antipyretic efficacy of ibuprofen and acetaminophen in children with febrile seizures. Arch Pediatr Adolesc Med. 1995 Jun;149(6):632-7. PMID: 7767417.

" None Not dangerous goods.

LKT T2833 1-Thio-β-D-glucose Tetraacetate 250 mg 42.2 Imaging agent; Maillard reaction inhibitor. 2,3,4,6-Tetra-O-acetyl-1-thio-β-D-glucopyranose 19879-84-6 ≥98% 364.4 C14H20O9S CC(=O)OCC1C(C(C(C(O1)S)OC(=O)C)OC(=O)C)OC(=O)C Ambient Ambient "Welling MM, Alberto R. Performance of a 99mTc-labelled 1-thio-beta-D-glucose 2,3,4,6-tetra-acetate analogue in the detection of infections and tumours in mice: a comparison with [18F]FDG. Nucl Med Commun. 2010 Mar;31(3):239-48. PMID: 20032803.

Csapó J, Varga-Visi E, Lóki K, et al. The influence of extrusion on loss and racemization of amino acids. Amino Acids. 2008 Feb;34(2):287-92. PMID: 17245615.

" Not dangerous goods.

LKT T2833 1-Thio-β-D-glucose Tetraacetate 1 g 125.9 Imaging agent; Maillard reaction inhibitor. 2,3,4,6-Tetra-O-acetyl-1-thio-β-D-glucopyranose 19879-84-6 ≥98% 364.4 C14H20O9S CC(=O)OCC1C(C(C(C(O1)S)OC(=O)C)OC(=O)C)OC(=O)C Ambient Ambient "Welling MM, Alberto R. Performance of a 99mTc-labelled 1-thio-beta-D-glucose 2,3,4,6-tetra-acetate analogue in the detection of infections and tumours in mice: a comparison with [18F]FDG. Nucl Med Commun. 2010 Mar;31(3):239-48. PMID: 20032803.

Csapó J, Varga-Visi E, Lóki K, et al. The influence of extrusion on loss and racemization of amino acids. Amino Acids. 2008 Feb;34(2):287-92. PMID: 17245615.

" Not dangerous goods.

LKT I0502 Ibandronate Sodium Monohydrate 50 mg 169.9 Bisphosphonate. [1-Hydroxy-3-(methylpentylamino)propylidene]bis- phosphonic acid Ibandronic acid sodium salt 138926-19-9 ≥98% 359.21 C9H22NNaO7P2 H2O CCCCCN(C)CCC(O)(P(=O)(O)O)P(=O)(O)[O-].O.[Na+] Ambient Ambient Soluble in water. "Ziebart T, Pabst A, Klein MO, et al. Bisphosphonates: restrictions for vasculogenesis and angiogenesis: inhibition of cell function of endothelial progenitor cells and mature endothelial cells in vitro. Clin Oral Investig. 2011 Feb;15(1):105-11. PMID: 20024592.

Zhou Q, Zhao ZN, Cheng JT, et al. Ibandronate promotes osteogenic differentiation of periodontal ligament stem cells by regulating the expression of microRNAs. Biochem Biophys Res Commun. 2011 Jan 7;404(1):127-32. PMID: 21108928.

Epstein S, Zaidi M. Biological properties and mechanism of action of ibandronate: application to the treatment of osteoporosis. Bone. 2005 Oct;37(4):433-40. PMID: 16046205.

" None Not dangerous goods.

LKT I0502 Ibandronate Sodium Monohydrate 100 mg 305.9 Bisphosphonate. [1-Hydroxy-3-(methylpentylamino)propylidene]bis- phosphonic acid Ibandronic acid sodium salt 138926-19-9 ≥98% 359.21 C9H22NNaO7P2 H2O CCCCCN(C)CCC(O)(P(=O)(O)O)P(=O)(O)[O-].O.[Na+] Ambient Ambient Soluble in water. "Ziebart T, Pabst A, Klein MO, et al. Bisphosphonates: restrictions for vasculogenesis and angiogenesis: inhibition of cell function of endothelial progenitor cells and mature endothelial cells in vitro. Clin Oral Investig. 2011 Feb;15(1):105-11. PMID: 20024592.

Zhou Q, Zhao ZN, Cheng JT, et al. Ibandronate promotes osteogenic differentiation of periodontal ligament stem cells by regulating the expression of microRNAs. Biochem Biophys Res Commun. 2011 Jan 7;404(1):127-32. PMID: 21108928.

Epstein S, Zaidi M. Biological properties and mechanism of action of ibandronate: application to the treatment of osteoporosis. Bone. 2005 Oct;37(4):433-40. PMID: 16046205.

" None Not dangerous goods.

LKT T2817 Theophylline 100 g 47.6 Methylxanthine; PDE inhibitor, A1/2 adenosine antagonist. 3,7-Dihydro-1,3-dimethyl-1H-purine-2,6-dione Theophylline anhydrous; 1,3-Dimethylxanthine; Diphyllin; Elixicon; Sustaire 58-55-9 ≥98% 180.16 C7H8N4O2 CN1C2=C(C(=O)N(C1=O)C)NC=N2 Ambient Ambient Slightly soluble in water. "Dubuis E, Wortley MA, Grace MS, et al. Theophylline inhibits the cough reflex through a novel mechanism of action. J Allergy Clin Immunol. 2014 Jun;133(6):1588-98. PMID: 24406072.

Barnes PJ. Theophylline. Am J Respir Crit Care Med. 2013 Oct 15;188(8):901-6. PMID: 23672674.

Essayan DM. Cyclic nucleotide phosphodiesterases. J Allergy Clin Immunol. 2001 Nov;108(5):671-80. PMID: 11692087.

Daly JW, Jacobson KA, Ukena D. Adenosine receptors: development of selective agonists and antagonists. Prog Clin Biol Res. 1987;230:41-63. PMID: 3588607.

" Xn "UN number: 2811     Class: 6.1     Packing Group: III

Proper shipping name: Toxic solid, organic, n.o.s. (Theophylline)"

LKT T2817 Theophylline 250 g 95.1 Methylxanthine; PDE inhibitor, A1/2 adenosine antagonist. 3,7-Dihydro-1,3-dimethyl-1H-purine-2,6-dione Theophylline anhydrous; 1,3-Dimethylxanthine; Diphyllin; Elixicon; Sustaire 58-55-9 ≥98% 180.16 C7H8N4O2 CN1C2=C(C(=O)N(C1=O)C)NC=N2 Ambient Ambient Slightly soluble in water. "Dubuis E, Wortley MA, Grace MS, et al. Theophylline inhibits the cough reflex through a novel mechanism of action. J Allergy Clin Immunol. 2014 Jun;133(6):1588-98. PMID: 24406072.

Barnes PJ. Theophylline. Am J Respir Crit Care Med. 2013 Oct 15;188(8):901-6. PMID: 23672674.

Essayan DM. Cyclic nucleotide phosphodiesterases. J Allergy Clin Immunol. 2001 Nov;108(5):671-80. PMID: 11692087.

Daly JW, Jacobson KA, Ukena D. Adenosine receptors: development of selective agonists and antagonists. Prog Clin Biol Res. 1987;230:41-63. PMID: 3588607.

" Xn "UN number: 2811     Class: 6.1     Packing Group: III

Proper shipping name: Toxic solid, organic, n.o.s. (Theophylline)"

LKT I1257 Idoxuridine 500 mg 63.1 Nucleoside (deoxyuridine) analog; DNA chain terminator. 2'-Deoxy-5-iodouridine IdU' IdUR; IUdR; IdUrd; Dendrid; (+)-5-Iodo-2'-deoxyuridine 54-42-2 ≥98% 354.1 C9H11IN2O5 C1C(C(OC1N2C=C(C(=O)NC2=O)I)CO)O Ambient -20°C Slightly soluble in water (2 mg/ml) or acetone (1.6 mg/ml). "Wilhelmus KR. Antiviral treatment and other therapeutic interventions for herpes simplex virus epithelial keratitis. Cochrane Database Syst Rev. 2010 Dec 8;(12):CD002898. PMID: 21154352.

Schultz CJ, Gaffney DK, Lindstrom MJ, et al. Iododeoxyuridine radiosensitization of human glioblastoma cells exposed to acute and chronic gamma irradiation: mechanistic implications and clinical relevance. Cancer J Sci Am. 1995 Jul-Aug;1(2):151-61. Erratum in: Cancer J Sci Am. 1996 Jan-Feb;2(1):15.  PMID: 9166468.

" Mut., Carc., Repr. Not dangerous goods.

LKT I1257 Idoxuridine 1 g 115.3 Nucleoside (deoxyuridine) analog; DNA chain terminator. 2'-Deoxy-5-iodouridine IdU' IdUR; IUdR; IdUrd; Dendrid; (+)-5-Iodo-2'-deoxyuridine 54-42-2 ≥98% 354.1 C9H11IN2O5 C1C(C(OC1N2C=C(C(=O)NC2=O)I)CO)O Ambient -20°C Slightly soluble in water (2 mg/ml) or acetone (1.6 mg/ml). "Wilhelmus KR. Antiviral treatment and other therapeutic interventions for herpes simplex virus epithelial keratitis. Cochrane Database Syst Rev. 2010 Dec 8;(12):CD002898. PMID: 21154352.

Schultz CJ, Gaffney DK, Lindstrom MJ, et al. Iododeoxyuridine radiosensitization of human glioblastoma cells exposed to acute and chronic gamma irradiation: mechanistic implications and clinical relevance. Cancer J Sci Am. 1995 Jul-Aug;1(2):151-61. Erratum in: Cancer J Sci Am. 1996 Jan-Feb;2(1):15.  PMID: 9166468.

" Mut., Carc., Repr. Not dangerous goods.

LKT I1400 Idarubicin Hydrochloride 1 mg 40.7 Anthracycline, DNA intercalator; topoisomerase II inhibitor. (7S,9S)-9-Acetyl-7-[(3-amino-2,3,6-trideoxy-α-L- lyxo-hexopyranosyl)oxy]-7,8,9,10-tetrahydro-6,9,11- trihydroxy-5,12-naphthacenedione hydrochloride Idamycin; Zavedos 57852-57-0 ≥98% 533.96 C26H27NO9 HCl CC1C(C(CC(O1)OC2CC(CC3=C(C4=C(C(=C23)O)C(=O)C5=CC=CC=C5C4=O)O)(C(=O)C)O)N)O.Cl Ambient -20°C Soluble in water and methanol. "Eda Satana Kara H. Redox mechanism of anticancer drug idarubicin and in-situ evaluation of interaction with DNA using an electrochemical biosensor. Bioelectrochemistry. 2014 Oct;99:17-23. PMID: 24967755.

Pang B, Qiao X, Janssen L, et al. Drug-induced histone eviction from open chromatin contributes to the chemotherapeutic effects of doxorubicin. Nat Commun. 2013;4:1908. PMID: 23715267.

Crivellari D, Lombardi D, Spazzapan S, et al. New oral drugs in older patients: a review of idarubicin in elderly patients. Crit Rev Oncol Hematol. 2004 Feb;49(2):153-63. PMID: 15012975.

" T+ "UN number: 2811     Class: 6.1     Packing Group: II

Proper shipping name: Toxic solid, organic, n.o.s. (Idarubicin Hydrochloride)"

LKT T2816 L-Theanine 1 g 45.3 Non-essential amino acid found in Camellia and Boletus, glutamic acid analog; weak AMPA and NMDA agonist. N-Ethyl-L-glutamine Theanine 3081-61-6 ≥98% 174.19 C7H14N2O3 CCNC(=O)CCC(C(=O)O)N Ambient Ambient Soluble in water or ethanol. "Park SK, Jung IC, Lee WK, et al. A combination of green tea extract and l-theanine improves memory and attention in subjects with mild cognitive impairment: a double-blind placebo-controlled study. J Med Food. 2011 Apr;14(4):334-43. PMID: 21303262.

Ritsner MS, Miodownik C, Ratner Y, et al. L-theanine relieves positive, activation, and anxiety symptoms in patients with schizophrenia and schizoaffective disorder: an 8-week, randomized, double-blind, placebo-controlled, 2-center study. J Clin Psychiatry. 2011 Jan;72(1):34-42. PMID: 21208586.

Haskell CF, Kennedy DO, Milne AL, et al. The effects of L-theanine, caffeine and their combination on cognition and mood. Biol Psychol. 2008 Feb;77(2):113-22. PMID: 18006208.

Egashira N, Ishigami N, Pu F, et al. Theanine prevents memory impairment induced by repeated cerebral ischemia in rats. Phytother Res. 2008 Jan;22(1):65-8. PMID: 17705146.

Nathan PJ, Lu K, Gray M, et al. The neuropharmacology of L-theanine(N-ethyl-L-glutamine): a possible neuroprotective and cognitive enhancing agent. J Herb Pharmacother. 2006;6(2):21-30. PMID: 17182482.

" None Not dangerous goods.

LKT I1400 Idarubicin Hydrochloride 5 mg 95.1 Anthracycline, DNA intercalator; topoisomerase II inhibitor. (7S,9S)-9-Acetyl-7-[(3-amino-2,3,6-trideoxy-α-L- lyxo-hexopyranosyl)oxy]-7,8,9,10-tetrahydro-6,9,11- trihydroxy-5,12-naphthacenedione hydrochloride Idamycin; Zavedos 57852-57-0 ≥98% 533.96 C26H27NO9 HCl CC1C(C(CC(O1)OC2CC(CC3=C(C4=C(C(=C23)O)C(=O)C5=CC=CC=C5C4=O)O)(C(=O)C)O)N)O.Cl Ambient -20°C Soluble in water and methanol. "Eda Satana Kara H. Redox mechanism of anticancer drug idarubicin and in-situ evaluation of interaction with DNA using an electrochemical biosensor. Bioelectrochemistry. 2014 Oct;99:17-23. PMID: 24967755.

Pang B, Qiao X, Janssen L, et al. Drug-induced histone eviction from open chromatin contributes to the chemotherapeutic effects of doxorubicin. Nat Commun. 2013;4:1908. PMID: 23715267.

Crivellari D, Lombardi D, Spazzapan S, et al. New oral drugs in older patients: a review of idarubicin in elderly patients. Crit Rev Oncol Hematol. 2004 Feb;49(2):153-63. PMID: 15012975.

" T+ "UN number: 2811     Class: 6.1     Packing Group: II

Proper shipping name: Toxic solid, organic, n.o.s. (Idarubicin Hydrochloride)"

LKT T2816 L-Theanine 5 g 155.4 Non-essential amino acid found in Camellia and Boletus, glutamic acid analog; weak AMPA and NMDA agonist. N-Ethyl-L-glutamine Theanine 3081-61-6 ≥98% 174.19 C7H14N2O3 CCNC(=O)CCC(C(=O)O)N Ambient Ambient Soluble in water or ethanol. "Park SK, Jung IC, Lee WK, et al. A combination of green tea extract and l-theanine improves memory and attention in subjects with mild cognitive impairment: a double-blind placebo-controlled study. J Med Food. 2011 Apr;14(4):334-43. PMID: 21303262.

Ritsner MS, Miodownik C, Ratner Y, et al. L-theanine relieves positive, activation, and anxiety symptoms in patients with schizophrenia and schizoaffective disorder: an 8-week, randomized, double-blind, placebo-controlled, 2-center study. J Clin Psychiatry. 2011 Jan;72(1):34-42. PMID: 21208586.

Haskell CF, Kennedy DO, Milne AL, et al. The effects of L-theanine, caffeine and their combination on cognition and mood. Biol Psychol. 2008 Feb;77(2):113-22. PMID: 18006208.

Egashira N, Ishigami N, Pu F, et al. Theanine prevents memory impairment induced by repeated cerebral ischemia in rats. Phytother Res. 2008 Jan;22(1):65-8. PMID: 17705146.

Nathan PJ, Lu K, Gray M, et al. The neuropharmacology of L-theanine(N-ethyl-L-glutamine): a possible neuroprotective and cognitive enhancing agent. J Herb Pharmacother. 2006;6(2):21-30. PMID: 17182482.

" None Not dangerous goods.

LKT T2816 L-Theanine 25 g 491.8 Non-essential amino acid found in Camellia and Boletus, glutamic acid analog; weak AMPA and NMDA agonist. N-Ethyl-L-glutamine Theanine 3081-61-6 ≥98% 174.19 C7H14N2O3 CCNC(=O)CCC(C(=O)O)N Ambient Ambient Soluble in water or ethanol. "Park SK, Jung IC, Lee WK, et al. A combination of green tea extract and l-theanine improves memory and attention in subjects with mild cognitive impairment: a double-blind placebo-controlled study. J Med Food. 2011 Apr;14(4):334-43. PMID: 21303262.

Ritsner MS, Miodownik C, Ratner Y, et al. L-theanine relieves positive, activation, and anxiety symptoms in patients with schizophrenia and schizoaffective disorder: an 8-week, randomized, double-blind, placebo-controlled, 2-center study. J Clin Psychiatry. 2011 Jan;72(1):34-42. PMID: 21208586.

Haskell CF, Kennedy DO, Milne AL, et al. The effects of L-theanine, caffeine and their combination on cognition and mood. Biol Psychol. 2008 Feb;77(2):113-22. PMID: 18006208.

Egashira N, Ishigami N, Pu F, et al. Theanine prevents memory impairment induced by repeated cerebral ischemia in rats. Phytother Res. 2008 Jan;22(1):65-8. PMID: 17705146.

Nathan PJ, Lu K, Gray M, et al. The neuropharmacology of L-theanine(N-ethyl-L-glutamine): a possible neuroprotective and cognitive enhancing agent. J Herb Pharmacother. 2006;6(2):21-30. PMID: 17182482.

" None Not dangerous goods.

LKT I1418 Idebenone 10 mg 54.4 Synthetic quinone CoQ analog, promotes mitochondrial respiration and ATP production. 2-(10-Hydroxydecyl)-5,6-dimethoxy-3-methyl-2,5-cyclohexadiene-1,4-benzoquinone Avan; Daruma; Mnesis 58186-27-9 ≥98% 324.41 C18H28O5 CC1=C(C(=O)C(=C(C1=O)OC)OC)CCCCCCCCCCO Ambient 4°C Soluble in organic solvents. Practically insoluble in water. "Buyse GM, Van der Mieren G, Erb M, et al. Long-term blinded placebo-controlled study of SNT-MC17/idebenone in the dystrophin deficient mdx mouse: cardiac protection and improved exercise performance. Eur Heart J. 2009 Jan;30(1):116-24. PMID: 18784063.

Di Prospero NA, Baker A, Jeffries N, et al. Neurological effects of high-dose idebenone in patients with Friedreich's ataxia: a randomised, placebo-controlled trial. Lancet Neurol. 2007 Oct;6(10):878-86. PMID: 17826341.

Gutzmann H, Kühl KP, Hadler D, et al. Safety and efficacy of idebenone versus tacrine in patients with Alzheimer's disease: results of a randomized, double-blind, parallel-group multicenter study. Pharmacopsychiatry. 2002 Jan;35(1):12-8. PMID: 11819153.

Liu XJ, Wu WT. Effects of ligustrazine, tanshinone II A, ubiquinone, and idebenone on mouse water maze performance. Zhongguo Yao Li Xue Bao. 1999 Nov;20(11):987-90. PMID: 11270979.

Suno M, Nagaoka A. Effect of idebenone and various nootropic drugs on lipid peroxidation in rat brain homogenate in the presence of succinate. Nihon Yakurigaku Zasshi. 1988 May;91(5):295-9. PMID: 3410376.

" None Not dangerous goods.

LKT I1418 Idebenone 25 mg 108.8 Synthetic quinone CoQ analog, promotes mitochondrial respiration and ATP production. 2-(10-Hydroxydecyl)-5,6-dimethoxy-3-methyl-2,5-cyclohexadiene-1,4-benzoquinone Avan; Daruma; Mnesis 58186-27-9 ≥98% 324.41 C18H28O5 CC1=C(C(=O)C(=C(C1=O)OC)OC)CCCCCCCCCCO Ambient 4°C Soluble in organic solvents. Practically insoluble in water. "Buyse GM, Van der Mieren G, Erb M, et al. Long-term blinded placebo-controlled study of SNT-MC17/idebenone in the dystrophin deficient mdx mouse: cardiac protection and improved exercise performance. Eur Heart J. 2009 Jan;30(1):116-24. PMID: 18784063.

Di Prospero NA, Baker A, Jeffries N, et al. Neurological effects of high-dose idebenone in patients with Friedreich's ataxia: a randomised, placebo-controlled trial. Lancet Neurol. 2007 Oct;6(10):878-86. PMID: 17826341.

Gutzmann H, Kühl KP, Hadler D, et al. Safety and efficacy of idebenone versus tacrine in patients with Alzheimer's disease: results of a randomized, double-blind, parallel-group multicenter study. Pharmacopsychiatry. 2002 Jan;35(1):12-8. PMID: 11819153.

Liu XJ, Wu WT. Effects of ligustrazine, tanshinone II A, ubiquinone, and idebenone on mouse water maze performance. Zhongguo Yao Li Xue Bao. 1999 Nov;20(11):987-90. PMID: 11270979.

Suno M, Nagaoka A. Effect of idebenone and various nootropic drugs on lipid peroxidation in rat brain homogenate in the presence of succinate. Nihon Yakurigaku Zasshi. 1988 May;91(5):295-9. PMID: 3410376.

" None Not dangerous goods.

LKT I1418 Idebenone 100 mg 339.8 Synthetic quinone CoQ analog, promotes mitochondrial respiration and ATP production. 2-(10-Hydroxydecyl)-5,6-dimethoxy-3-methyl-2,5-cyclohexadiene-1,4-benzoquinone Avan; Daruma; Mnesis 58186-27-9 ≥98% 324.41 C18H28O5 CC1=C(C(=O)C(=C(C1=O)OC)OC)CCCCCCCCCCO Ambient 4°C Soluble in organic solvents. Practically insoluble in water. "Buyse GM, Van der Mieren G, Erb M, et al. Long-term blinded placebo-controlled study of SNT-MC17/idebenone in the dystrophin deficient mdx mouse: cardiac protection and improved exercise performance. Eur Heart J. 2009 Jan;30(1):116-24. PMID: 18784063.

Di Prospero NA, Baker A, Jeffries N, et al. Neurological effects of high-dose idebenone in patients with Friedreich's ataxia: a randomised, placebo-controlled trial. Lancet Neurol. 2007 Oct;6(10):878-86. PMID: 17826341.

Gutzmann H, Kühl KP, Hadler D, et al. Safety and efficacy of idebenone versus tacrine in patients with Alzheimer's disease: results of a randomized, double-blind, parallel-group multicenter study. Pharmacopsychiatry. 2002 Jan;35(1):12-8. PMID: 11819153.

Liu XJ, Wu WT. Effects of ligustrazine, tanshinone II A, ubiquinone, and idebenone on mouse water maze performance. Zhongguo Yao Li Xue Bao. 1999 Nov;20(11):987-90. PMID: 11270979.

Suno M, Nagaoka A. Effect of idebenone and various nootropic drugs on lipid peroxidation in rat brain homogenate in the presence of succinate. Nihon Yakurigaku Zasshi. 1988 May;91(5):295-9. PMID: 3410376.

" None Not dangerous goods.

LKT T2801 Thapsigargin 1 mg 95.1 Sesquiterpene lactone found in Thapsia, used to induce ER stress; SERCA inhibitor. "Octanoic acid, 6-(acetyloxy)-2,3,3a,4,5,6,6a,7,8,9b-

decahydro-3,3a-dihydroxy-3,6,9-trimethyl-8-((2- methyl-1-oxo-2-butenyl)oxy)-2-oxo-4-(1-oxobutoxy)- azuleno(4,5-b)furan-7-yl ester, (3S-(3α,3aβ,4α,6β,- 6aβ,7β,8α(Z),9bα))-" Thapsigargine; Tg 67526-95-8 ≥96% 650.75 C34H50O12 CCCCCCCC(=O)OC1C2C(=C(C1OC(=O)C(=CC)C)C)C3C(C(CC2(C)OC(=O)C)OC(=O)CCC)(C(C(=O)O3)(C)O)O Protect from light. Ambient -20°C Soluble in DMSO, ethanol, or acetonitrile. "Zhang X, Yuan Y, Jiang L, et al. Endoplasmic reticulum stress induced by tunicamycin and thapsigargin protects against transient ischemic brain injury: Involvement of PARK2-dependent mitophagy. Autophagy. 2014 Oct 1;10(10):1801-13. PMID: 25126734.

Wang H, Jia XZ, Sui CJ, et al. Effects of thapsigargin on the proliferation and survival of human rheumatoid arthritis synovial cells. ScientificWorldJournal. 2014 Feb 9;2014:605416. PMID: 24688409.

Rogers TB, Inesi G, Wade R, et al. Use of thapsigargin to study Ca2+ homeostasis in cardiac cells. Biosci Rep. 1995 Oct;15(5):341-9. PMID: 8825036.

" Xn, Xi Not dangerous goods.

LKT T2801 Thapsigargin 5 mg 400.9 Sesquiterpene lactone found in Thapsia, used to induce ER stress; SERCA inhibitor. "Octanoic acid, 6-(acetyloxy)-2,3,3a,4,5,6,6a,7,8,9b-

decahydro-3,3a-dihydroxy-3,6,9-trimethyl-8-((2- methyl-1-oxo-2-butenyl)oxy)-2-oxo-4-(1-oxobutoxy)- azuleno(4,5-b)furan-7-yl ester, (3S-(3α,3aβ,4α,6β,- 6aβ,7β,8α(Z),9bα))-" Thapsigargine; Tg 67526-95-8 ≥96% 650.75 C34H50O12 CCCCCCCC(=O)OC1C2C(=C(C1OC(=O)C(=CC)C)C)C3C(C(CC2(C)OC(=O)C)OC(=O)CCC)(C(C(=O)O3)(C)O)O Protect from light. Ambient -20°C Soluble in DMSO, ethanol, or acetonitrile. "Zhang X, Yuan Y, Jiang L, et al. Endoplasmic reticulum stress induced by tunicamycin and thapsigargin protects against transient ischemic brain injury: Involvement of PARK2-dependent mitophagy. Autophagy. 2014 Oct 1;10(10):1801-13. PMID: 25126734.

Wang H, Jia XZ, Sui CJ, et al. Effects of thapsigargin on the proliferation and survival of human rheumatoid arthritis synovial cells. ScientificWorldJournal. 2014 Feb 9;2014:605416. PMID: 24688409.

Rogers TB, Inesi G, Wade R, et al. Use of thapsigargin to study Ca2+ homeostasis in cardiac cells. Biosci Rep. 1995 Oct;15(5):341-9. PMID: 8825036.

" Xn, Xi Not dangerous goods.

LKT T2800 Thalidomide 100 mg 67.9 Immunomodulator; teratogen. (±)-2-(2,6-Dioxo-3-piperidinyl)-1H-isoindole-1,3(2H)-dione 1,3-Dioxo-2-(2,6-dioxopiperidin-3-yl)isoindoline; Actimid; Calmore; Distaval; Sedimide;Telagan 50-35-1 ≥98% 258.23 C13H10N2O4 C1CC(=O)NC(=O)C1N2C(=O)C3=CC=CC=C3C2=O Ambient Ambient Insoluble in water and ethanol. Soluble in DMSO (56mg/mL). "Lien IC, Horng LY, Hsu PL, et al. Internal ribosome entry site of bFGF is the target of thalidomide for IMiDs development in multiple myeloma. Genes Cancer. 2014 Mar;5(3-4):127-41. PMID: 25053990.

Xu J, Zheng C, Huang Y, et al. Efficacy of thalidomide on trinitrobenzene sulfonate-induced colitis in young rats and its mechanism. Chin Med J (Engl). 2014;127(12):2368-75. PMID: 24931258.

Zhou S, Wang F, Hsieh TC, et al. Thalidomide-a notorious sedative to a wonder anticancer drug. Curr Med Chem. 2013;20(33):4102-8. PMID: 23931282.

" T "UN number: 2811     Class: 6.1     Packing Group: III

Proper shipping name: Toxic solid, organic, n.o.s. ((+/-)-Thalidomide)"

LKT T2800 Thalidomide 250 mg 136 Immunomodulator; teratogen. (±)-2-(2,6-Dioxo-3-piperidinyl)-1H-isoindole-1,3(2H)-dione 1,3-Dioxo-2-(2,6-dioxopiperidin-3-yl)isoindoline; Actimid; Calmore; Distaval; Sedimide;Telagan 50-35-1 ≥98% 258.23 C13H10N2O4 C1CC(=O)NC(=O)C1N2C(=O)C3=CC=CC=C3C2=O Ambient Ambient Insoluble in water and ethanol. Soluble in DMSO (56mg/mL). "Lien IC, Horng LY, Hsu PL, et al. Internal ribosome entry site of bFGF is the target of thalidomide for IMiDs development in multiple myeloma. Genes Cancer. 2014 Mar;5(3-4):127-41. PMID: 25053990.

Xu J, Zheng C, Huang Y, et al. Efficacy of thalidomide on trinitrobenzene sulfonate-induced colitis in young rats and its mechanism. Chin Med J (Engl). 2014;127(12):2368-75. PMID: 24931258.

Zhou S, Wang F, Hsieh TC, et al. Thalidomide-a notorious sedative to a wonder anticancer drug. Curr Med Chem. 2013;20(33):4102-8. PMID: 23931282.

" T "UN number: 2811     Class: 6.1     Packing Group: III

Proper shipping name: Toxic solid, organic, n.o.s. ((+/-)-Thalidomide)"

LKT T2800 Thalidomide 500 mg 244.5 Immunomodulator; teratogen. (±)-2-(2,6-Dioxo-3-piperidinyl)-1H-isoindole-1,3(2H)-dione 1,3-Dioxo-2-(2,6-dioxopiperidin-3-yl)isoindoline; Actimid; Calmore; Distaval; Sedimide;Telagan 50-35-1 ≥98% 258.23 C13H10N2O4 C1CC(=O)NC(=O)C1N2C(=O)C3=CC=CC=C3C2=O Ambient Ambient Insoluble in water and ethanol. Soluble in DMSO (56mg/mL). "Lien IC, Horng LY, Hsu PL, et al. Internal ribosome entry site of bFGF is the target of thalidomide for IMiDs development in multiple myeloma. Genes Cancer. 2014 Mar;5(3-4):127-41. PMID: 25053990.

Xu J, Zheng C, Huang Y, et al. Efficacy of thalidomide on trinitrobenzene sulfonate-induced colitis in young rats and its mechanism. Chin Med J (Engl). 2014;127(12):2368-75. PMID: 24931258.

Zhou S, Wang F, Hsieh TC, et al. Thalidomide-a notorious sedative to a wonder anticancer drug. Curr Med Chem. 2013;20(33):4102-8. PMID: 23931282.

" T "UN number: 2811     Class: 6.1     Packing Group: III

Proper shipping name: Toxic solid, organic, n.o.s. ((+/-)-Thalidomide)"

LKT I2056 Ifosfamide 25 mg 40.7 Nitrogen mustard, DNA alkylator. N, 3-Bis(2-chloroethyl)-tetrahydro-2H-1,3,2-oxaza- phosphorin-2-amine 2-oxide Holoxan; Ifex; Ifomide; Isoendoxan; Isophosphamide; Mitoxana 3778-73-2 ≥98% 261.09 C7H15Cl2N2O2P C1CN(P(=O)(OC1)NCCCl)CCCl Ambient Ambient Soluble in water. "Vincenzi B, Frezza AM, Santini D, et al. New therapies in soft tissue sarcoma. Expert Opin Emerg Drugs. 2010 Jun;15(2):237-48. PMID: 20465449.

Nissim I, Horyn O, Daikhin Y, et al. Ifosfamide-induced nephrotoxicity: mechanism and prevention. Cancer Res. 2006 Aug 1;66(15):7824-31. PMID: 16885387.

" T "UN number: 2811     Class: 6.1     Packing group:  III

Proper shipping name:  Toxic solids, organic, n.o.s. (Ifosfamide)

Poison Inhalation Hazard:  No"

LKT I2056 Ifosfamide 50 mg 47.6 Nitrogen mustard, DNA alkylator. N, 3-Bis(2-chloroethyl)-tetrahydro-2H-1,3,2-oxaza- phosphorin-2-amine 2-oxide Holoxan; Ifex; Ifomide; Isoendoxan; Isophosphamide; Mitoxana 3778-73-2 ≥98% 261.09 C7H15Cl2N2O2P C1CN(P(=O)(OC1)NCCCl)CCCl Ambient Ambient Soluble in water. "Vincenzi B, Frezza AM, Santini D, et al. New therapies in soft tissue sarcoma. Expert Opin Emerg Drugs. 2010 Jun;15(2):237-48. PMID: 20465449.

Nissim I, Horyn O, Daikhin Y, et al. Ifosfamide-induced nephrotoxicity: mechanism and prevention. Cancer Res. 2006 Aug 1;66(15):7824-31. PMID: 16885387.

" T "UN number: 2811     Class: 6.1     Packing group:  III

Proper shipping name:  Toxic solids, organic, n.o.s. (Ifosfamide)

Poison Inhalation Hazard:  No"

LKT I4000 Ikarugamycin 0.5 mg 209.7 Protein translation inhibitor. 36531-78-9 ≥98% 480.64 C29H40N2O4 CCC1C(CC2C1C=CC3C2CC4C3CC=CC(=O)NCCCC5C(=O)C(=C(C=C4)O)C(=O)N5)C Ambient -20°C "Popescu R, Heiss EH, Ferk F, et al. Ikarugamycin induces DNA damage, intracellular calcium increase, p38 MAP kinase activation and apoptosis in HL-60 human promyelocytic leukemia cells. Mutat Res. 2011 May 10;709-710:60-6. PMID: 21392513.

Luo T, Fredericksen BL, Hasumi K, et al. Human immunodeficiency virus type 1 Nef-induced CD4 cell surface downregulation is inhibited by ikarugamycin. J Virol. 2001 Mar;75(5):2488-92. PMID: 11160755.

Hasumi K, Shinohara C, Naganuma S, et al. Inhibition of the uptake of oxidized low-density lipoprotein in macrophage J774 by the antibiotic ikarugamycin. Eur J Biochem. 1992 Apr 15;205(2):841-6. PMID: 1572375.

Jomon K, Kuroda Y, Ajisaka M, et al. A new antibiotic, ikarugamycin. J Antibiot (Tokyo). 1972 May;25(5):271-80. PMID: 4625358.

" "UN number: 2811     Class: 6.1     Packing Group: III

Proper shipping name: Toxic solid, organic, n.o.s. (Ikarugamycin)"

LKT I4000 Ikarugamycin 1 mg 380.3 Protein translation inhibitor. 36531-78-9 ≥98% 480.64 C29H40N2O4 CCC1C(CC2C1C=CC3C2CC4C3CC=CC(=O)NCCCC5C(=O)C(=C(C=C4)O)C(=O)N5)C Ambient -20°C "Popescu R, Heiss EH, Ferk F, et al. Ikarugamycin induces DNA damage, intracellular calcium increase, p38 MAP kinase activation and apoptosis in HL-60 human promyelocytic leukemia cells. Mutat Res. 2011 May 10;709-710:60-6. PMID: 21392513.

Luo T, Fredericksen BL, Hasumi K, et al. Human immunodeficiency virus type 1 Nef-induced CD4 cell surface downregulation is inhibited by ikarugamycin. J Virol. 2001 Mar;75(5):2488-92. PMID: 11160755.

Hasumi K, Shinohara C, Naganuma S, et al. Inhibition of the uptake of oxidized low-density lipoprotein in macrophage J774 by the antibiotic ikarugamycin. Eur J Biochem. 1992 Apr 15;205(2):841-6. PMID: 1572375.

Jomon K, Kuroda Y, Ajisaka M, et al. A new antibiotic, ikarugamycin. J Antibiot (Tokyo). 1972 May;25(5):271-80. PMID: 4625358.

" "UN number: 2811     Class: 6.1     Packing Group: III

Proper shipping name: Toxic solid, organic, n.o.s. (Ikarugamycin)"

LKT I4000 Ikarugamycin 5 mg 1571.6 Protein translation inhibitor. 36531-78-9 ≥98% 480.64 C29H40N2O4 CCC1C(CC2C1C=CC3C2CC4C3CC=CC(=O)NCCCC5C(=O)C(=C(C=C4)O)C(=O)N5)C Ambient -20°C "Popescu R, Heiss EH, Ferk F, et al. Ikarugamycin induces DNA damage, intracellular calcium increase, p38 MAP kinase activation and apoptosis in HL-60 human promyelocytic leukemia cells. Mutat Res. 2011 May 10;709-710:60-6. PMID: 21392513.

Luo T, Fredericksen BL, Hasumi K, et al. Human immunodeficiency virus type 1 Nef-induced CD4 cell surface downregulation is inhibited by ikarugamycin. J Virol. 2001 Mar;75(5):2488-92. PMID: 11160755.

Hasumi K, Shinohara C, Naganuma S, et al. Inhibition of the uptake of oxidized low-density lipoprotein in macrophage J774 by the antibiotic ikarugamycin. Eur J Biochem. 1992 Apr 15;205(2):841-6. PMID: 1572375.

Jomon K, Kuroda Y, Ajisaka M, et al. A new antibiotic, ikarugamycin. J Antibiot (Tokyo). 1972 May;25(5):271-80. PMID: 4625358.

" "UN number: 2811     Class: 6.1     Packing Group: III

Proper shipping name: Toxic solid, organic, n.o.s. (Ikarugamycin)"

LKT I4934 Imipenem Monohydrate 25 mg 112.5 Carbapenem β-lactam; penicillin binding protein inhibitor. 74431-23-5 ≥98% 317.36 C12H17N3O4S H2O CC(C1C2CC(=C(N2C1=O)C(=O)O)SCCN=CN)O.O Ambient Ambient Water 10 mg/ml, methanol  5 mg/ml, ethanol 0.2 mg/ml "El-Gamal MI, Oh CH. Current status of carbapenem antibiotics. Curr Top Med Chem. 2010;10(18):1882-97. PMID: 20615191.

Clissold SP, Todd PA, Campoli-Richards DM. Imipenem/cilastatin. A review of its antibacterial activity, pharmacokinetic properties and therapeutic efficacy. Drugs. 1987 Mar;33(3):183-241. PMID: 3552595.

" Xi Not dangerous goods.

LKT I4934 Imipenem Monohydrate 100 mg 328.1 Carbapenem β-lactam; penicillin binding protein inhibitor. 74431-23-5 ≥98% 317.36 C12H17N3O4S H2O CC(C1C2CC(=C(N2C1=O)C(=O)O)SCCN=CN)O.O Ambient Ambient Water 10 mg/ml, methanol  5 mg/ml, ethanol 0.2 mg/ml "El-Gamal MI, Oh CH. Current status of carbapenem antibiotics. Curr Top Med Chem. 2010;10(18):1882-97. PMID: 20615191.

Clissold SP, Todd PA, Campoli-Richards DM. Imipenem/cilastatin. A review of its antibacterial activity, pharmacokinetic properties and therapeutic efficacy. Drugs. 1987 Mar;33(3):183-241. PMID: 3552595.

" Xi Not dangerous goods.

LKT I4934 Imipenem Monohydrate 500 mg 937.5 Carbapenem β-lactam; penicillin binding protein inhibitor. 74431-23-5 ≥98% 317.36 C12H17N3O4S H2O CC(C1C2CC(=C(N2C1=O)C(=O)O)SCCN=CN)O.O Ambient Ambient Water 10 mg/ml, methanol  5 mg/ml, ethanol 0.2 mg/ml "El-Gamal MI, Oh CH. Current status of carbapenem antibiotics. Curr Top Med Chem. 2010;10(18):1882-97. PMID: 20615191.

Clissold SP, Todd PA, Campoli-Richards DM. Imipenem/cilastatin. A review of its antibacterial activity, pharmacokinetic properties and therapeutic efficacy. Drugs. 1987 Mar;33(3):183-241. PMID: 3552595.

" Xi Not dangerous goods.

LKT I5034 Imiquimod 100 mg 67.9 Imidazoquinoline nucleoside analog; TLR-7/8 agonist, KCNA1/Kv1.1 and KCNA2/Kv1.2 K+ channel partial agonist, TREK-1/K2P2 and TRAAK/K2P4 K+ channel blocker. 1(2-Methyl-propyl)-1H-imidazol [4,5-c] quinolin- 4-amine Aldara; R-837 99011-02-6 ≥99.5% 240.3 C14H16N4 CC(C)CN1C=NC2=C1C3=CC=CC=C3N=C2N Ambient Ambient Insoluble in water, DMSO (3 mg/mL) or DMF. slightly soluble in water (warm to 37°C, vortex); insoluble in 100% ethanol. "Nazmi A, Mukherjee S, Kundu K, et al. TLR7 is a key regulator of innate immunity against Japanese encephalitis virus infection. Neurobiol Dis. 2014 Sep;69:235-47. PMID: 24909816.

Sohn KC, Li ZJ, Choi DK, et al. Imiquimod induces apoptosis of squamous cell carcinoma (SCC) cells via regulation of A20. PLoS One. 2014 Apr 17;9(4):e95337. PMID: 24743316.

Wolff F, Loipetzberger A, Gruber W, et al. Imiquimod directly inhibits Hedgehog signalling by stimulating adenosine receptor/protein kinase A-mediated GLI phosphorylation. Oncogene. 2013 Dec 12;32(50):5574-81. PMID: 23995793.

Yokogawa M, Takaishi M, Nakajima K, et al. Imiquimod attenuates the growth of UVB-induced SCC in mice through Th1/Th17 cells. Mol Carcinog. 2013 Oct;52(10):760-9. PMID: 22431065.

Lee J, Kim T, Hong J, et al. Imiquimod enhances excitability of dorsal root ganglion neurons by inhibiting background (K(2P)) and voltage-gated (K(v)1.1 and K(v)1.2) potassium channels. Mol Pain. 2012 Jan 11;8:2. PMID: 22233604.

Lee WR, Shen SC, Al-Suwayeh SA, et al. Skin permeation of small-molecule drugs, macromolecules, and nanoparticles mediated by a fractional carbon dioxide laser: the role of hair follicles. Pharm Res. 2013 Mar;30(3):792-802. PMID: 23138262.

" T "UN number: 2811     Class: 6.1     Packing Group: II

Proper shipping name: Toxic solid, organic, n.o.s. (Imiquimod)"

LKT I5034 Imiquimod 500 mg 190.3 Imidazoquinoline nucleoside analog; TLR-7/8 agonist, KCNA1/Kv1.1 and KCNA2/Kv1.2 K+ channel partial agonist, TREK-1/K2P2 and TRAAK/K2P4 K+ channel blocker. 1(2-Methyl-propyl)-1H-imidazol [4,5-c] quinolin- 4-amine Aldara; R-837 99011-02-6 ≥99.5% 240.3 C14H16N4 CC(C)CN1C=NC2=C1C3=CC=CC=C3N=C2N Ambient Ambient Insoluble in water, DMSO (3 mg/mL) or DMF. slightly soluble in water (warm to 37°C, vortex); insoluble in 100% ethanol. "Nazmi A, Mukherjee S, Kundu K, et al. TLR7 is a key regulator of innate immunity against Japanese encephalitis virus infection. Neurobiol Dis. 2014 Sep;69:235-47. PMID: 24909816.

Sohn KC, Li ZJ, Choi DK, et al. Imiquimod induces apoptosis of squamous cell carcinoma (SCC) cells via regulation of A20. PLoS One. 2014 Apr 17;9(4):e95337. PMID: 24743316.

Wolff F, Loipetzberger A, Gruber W, et al. Imiquimod directly inhibits Hedgehog signalling by stimulating adenosine receptor/protein kinase A-mediated GLI phosphorylation. Oncogene. 2013 Dec 12;32(50):5574-81. PMID: 23995793.

Yokogawa M, Takaishi M, Nakajima K, et al. Imiquimod attenuates the growth of UVB-induced SCC in mice through Th1/Th17 cells. Mol Carcinog. 2013 Oct;52(10):760-9. PMID: 22431065.

Lee J, Kim T, Hong J, et al. Imiquimod enhances excitability of dorsal root ganglion neurons by inhibiting background (K(2P)) and voltage-gated (K(v)1.1 and K(v)1.2) potassium channels. Mol Pain. 2012 Jan 11;8:2. PMID: 22233604.

Lee WR, Shen SC, Al-Suwayeh SA, et al. Skin permeation of small-molecule drugs, macromolecules, and nanoparticles mediated by a fractional carbon dioxide laser: the role of hair follicles. Pharm Res. 2013 Mar;30(3):792-802. PMID: 23138262.

" T "UN number: 2811     Class: 6.1     Packing Group: II

Proper shipping name: Toxic solid, organic, n.o.s. (Imiquimod)"

LKT I5034 Imiquimod 1 g 305.9 Imidazoquinoline nucleoside analog; TLR-7/8 agonist, KCNA1/Kv1.1 and KCNA2/Kv1.2 K+ channel partial agonist, TREK-1/K2P2 and TRAAK/K2P4 K+ channel blocker. 1(2-Methyl-propyl)-1H-imidazol [4,5-c] quinolin- 4-amine Aldara; R-837 99011-02-6 ≥99.5% 240.3 C14H16N4 CC(C)CN1C=NC2=C1C3=CC=CC=C3N=C2N Ambient Ambient Insoluble in water, DMSO (3 mg/mL) or DMF. slightly soluble in water (warm to 37°C, vortex); insoluble in 100% ethanol. "Nazmi A, Mukherjee S, Kundu K, et al. TLR7 is a key regulator of innate immunity against Japanese encephalitis virus infection. Neurobiol Dis. 2014 Sep;69:235-47. PMID: 24909816.

Sohn KC, Li ZJ, Choi DK, et al. Imiquimod induces apoptosis of squamous cell carcinoma (SCC) cells via regulation of A20. PLoS One. 2014 Apr 17;9(4):e95337. PMID: 24743316.

Wolff F, Loipetzberger A, Gruber W, et al. Imiquimod directly inhibits Hedgehog signalling by stimulating adenosine receptor/protein kinase A-mediated GLI phosphorylation. Oncogene. 2013 Dec 12;32(50):5574-81. PMID: 23995793.

Yokogawa M, Takaishi M, Nakajima K, et al. Imiquimod attenuates the growth of UVB-induced SCC in mice through Th1/Th17 cells. Mol Carcinog. 2013 Oct;52(10):760-9. PMID: 22431065.

Lee J, Kim T, Hong J, et al. Imiquimod enhances excitability of dorsal root ganglion neurons by inhibiting background (K(2P)) and voltage-gated (K(v)1.1 and K(v)1.2) potassium channels. Mol Pain. 2012 Jan 11;8:2. PMID: 22233604.

Lee WR, Shen SC, Al-Suwayeh SA, et al. Skin permeation of small-molecule drugs, macromolecules, and nanoparticles mediated by a fractional carbon dioxide laser: the role of hair follicles. Pharm Res. 2013 Mar;30(3):792-802. PMID: 23138262.

" T "UN number: 2811     Class: 6.1     Packing Group: II

Proper shipping name: Toxic solid, organic, n.o.s. (Imiquimod)"

LKT I5034 Imiquimod 5 g 815.4 Imidazoquinoline nucleoside analog; TLR-7/8 agonist, KCNA1/Kv1.1 and KCNA2/Kv1.2 K+ channel partial agonist, TREK-1/K2P2 and TRAAK/K2P4 K+ channel blocker. 1(2-Methyl-propyl)-1H-imidazol [4,5-c] quinolin- 4-amine Aldara; R-837 99011-02-6 ≥99.5% 240.3 C14H16N4 CC(C)CN1C=NC2=C1C3=CC=CC=C3N=C2N Ambient Ambient Insoluble in water, DMSO (3 mg/mL) or DMF. slightly soluble in water (warm to 37°C, vortex); insoluble in 100% ethanol. "Nazmi A, Mukherjee S, Kundu K, et al. TLR7 is a key regulator of innate immunity against Japanese encephalitis virus infection. Neurobiol Dis. 2014 Sep;69:235-47. PMID: 24909816.

Sohn KC, Li ZJ, Choi DK, et al. Imiquimod induces apoptosis of squamous cell carcinoma (SCC) cells via regulation of A20. PLoS One. 2014 Apr 17;9(4):e95337. PMID: 24743316.

Wolff F, Loipetzberger A, Gruber W, et al. Imiquimod directly inhibits Hedgehog signalling by stimulating adenosine receptor/protein kinase A-mediated GLI phosphorylation. Oncogene. 2013 Dec 12;32(50):5574-81. PMID: 23995793.

Yokogawa M, Takaishi M, Nakajima K, et al. Imiquimod attenuates the growth of UVB-induced SCC in mice through Th1/Th17 cells. Mol Carcinog. 2013 Oct;52(10):760-9. PMID: 22431065.

Lee J, Kim T, Hong J, et al. Imiquimod enhances excitability of dorsal root ganglion neurons by inhibiting background (K(2P)) and voltage-gated (K(v)1.1 and K(v)1.2) potassium channels. Mol Pain. 2012 Jan 11;8:2. PMID: 22233604.

Lee WR, Shen SC, Al-Suwayeh SA, et al. Skin permeation of small-molecule drugs, macromolecules, and nanoparticles mediated by a fractional carbon dioxide laser: the role of hair follicles. Pharm Res. 2013 Mar;30(3):792-802. PMID: 23138262.

" T "UN number: 2811     Class: 6.1     Packing Group: II

Proper shipping name: Toxic solid, organic, n.o.s. (Imiquimod)"

LKT I5072 Imazalil 5 g 65.6 Triazole; 14-α demethylase and aromatase inhibitor, AR antagonist. (+/-)-allyl 1-(2,4-dichlorophenyl)-2-imidazol-1-ylether ester Enilconazole 35554-44-0 ≥95%, titration; ≥70%, HPLC 297.18 C14H14Cl2N2O C=CCOC(CN1C=CN=C1)C2=C(C=C(C=C2)Cl)Cl Ambient Ambient 1400 mg/L H2O "Orton F, Rosivatz E, Scholze M, et al. Competitive androgen receptor antagonism as a factor determining the predictability of cumulative antiandrogenic effects of widely used pesticides. Environ Health Perspect. 2012 Nov;120(11):1578-84. PMID: 23008280.

Sun X, Wang J, Feng D, et al. PdCYP51B, a new putative sterol 14α-demethylase gene of Penicillium digitatum involved in resistance to imazalil and other fungicides inhibiting ergosterol synthesis. Appl Microbiol Biotechnol. 2011 Aug;91(4):1107-19. PMID: 21637936.

Zega G, De Bernardi F, Groppelli S, et al. Effects of the azole fungicide Imazalil on the development of the ascidian Ciona intestinalis (Chordata, Tunicata): morphological and molecular characterization of the induced phenotype. Aquat Toxicol. 2009 Feb 19;91(3):255-61. PMID: 19124165.

Sanderson JT, Boerma J, Lansbergen GW, et al. Induction and inhibition of aromatase (CYP19) activity by various classes of pesticides in H295R human adrenocortical carcinoma cells. Toxicol Appl Pharmacol. 2002 Jul 1;182(1):44-54. PMID: 12127262.

" Xn, Xi, N Not dangerous goods.

LKT I5072 Imazalil 10 g 84.3 Triazole; 14-α demethylase and aromatase inhibitor, AR antagonist. (+/-)-allyl 1-(2,4-dichlorophenyl)-2-imidazol-1-ylether ester Enilconazole 35554-44-0 ≥95%, titration; ≥70%, HPLC 297.18 C14H14Cl2N2O C=CCOC(CN1C=CN=C1)C2=C(C=C(C=C2)Cl)Cl Ambient Ambient 1400 mg/L H2O "Orton F, Rosivatz E, Scholze M, et al. Competitive androgen receptor antagonism as a factor determining the predictability of cumulative antiandrogenic effects of widely used pesticides. Environ Health Perspect. 2012 Nov;120(11):1578-84. PMID: 23008280.

Sun X, Wang J, Feng D, et al. PdCYP51B, a new putative sterol 14α-demethylase gene of Penicillium digitatum involved in resistance to imazalil and other fungicides inhibiting ergosterol synthesis. Appl Microbiol Biotechnol. 2011 Aug;91(4):1107-19. PMID: 21637936.

Zega G, De Bernardi F, Groppelli S, et al. Effects of the azole fungicide Imazalil on the development of the ascidian Ciona intestinalis (Chordata, Tunicata): morphological and molecular characterization of the induced phenotype. Aquat Toxicol. 2009 Feb 19;91(3):255-61. PMID: 19124165.

Sanderson JT, Boerma J, Lansbergen GW, et al. Induction and inhibition of aromatase (CYP19) activity by various classes of pesticides in H295R human adrenocortical carcinoma cells. Toxicol Appl Pharmacol. 2002 Jul 1;182(1):44-54. PMID: 12127262.

" Xn, Xi, N Not dangerous goods.

LKT I5072 Imazalil 100 g 497 Triazole; 14-α demethylase and aromatase inhibitor, AR antagonist. (+/-)-allyl 1-(2,4-dichlorophenyl)-2-imidazol-1-ylether ester Enilconazole 35554-44-0 ≥95%, titration; ≥70%, HPLC 297.18 C14H14Cl2N2O C=CCOC(CN1C=CN=C1)C2=C(C=C(C=C2)Cl)Cl Ambient Ambient 1400 mg/L H2O "Orton F, Rosivatz E, Scholze M, et al. Competitive androgen receptor antagonism as a factor determining the predictability of cumulative antiandrogenic effects of widely used pesticides. Environ Health Perspect. 2012 Nov;120(11):1578-84. PMID: 23008280.

Sun X, Wang J, Feng D, et al. PdCYP51B, a new putative sterol 14α-demethylase gene of Penicillium digitatum involved in resistance to imazalil and other fungicides inhibiting ergosterol synthesis. Appl Microbiol Biotechnol. 2011 Aug;91(4):1107-19. PMID: 21637936.

Zega G, De Bernardi F, Groppelli S, et al. Effects of the azole fungicide Imazalil on the development of the ascidian Ciona intestinalis (Chordata, Tunicata): morphological and molecular characterization of the induced phenotype. Aquat Toxicol. 2009 Feb 19;91(3):255-61. PMID: 19124165.

Sanderson JT, Boerma J, Lansbergen GW, et al. Induction and inhibition of aromatase (CYP19) activity by various classes of pesticides in H295R human adrenocortical carcinoma cells. Toxicol Appl Pharmacol. 2002 Jul 1;182(1):44-54. PMID: 12127262.

" Xn, Xi, N Not dangerous goods.

LKT I5213 Indole-3-carbinol 5 g 67.9 Indole, glucosinolate found in cruciferous vegetables. 3-Indomethanol; 3-Hydroxymethylindole; 3-Indolyl- carbinol 700-06-1 ≥98% 147.17 C9H9NO C1=CC=C2C(=C1)C(=CN2)CO Ambient -20°C Slightly soluble in cold water. "Choi HS, Jeon HJ, Lee OH, et al. Indole-3-carbinol, a vegetable phytochemical, inhibits adipogenesis by regulating cell cycle and AMPKα signaling. Biochimie. 2014 Sep;104:127-36. PMID: 24952351.

Mao CG, Tao ZZ, Chen Z, et al. Indole-3-carbinol inhibits nasopharyngeal carcinoma cell growth in vivo and in vitro through inhibition of the PI3K/Akt pathway. Exp Ther Med. 2014 Jul;8(1):207-12. PMID: 24944623.

Ping J, Gao AM, Xu D, et al. Therapeutic effect of indole-3-carbinol on pig serum-induced hepatic fibrosis in rats. Yao Xue Xue Bao. 2011 Aug;46(8):915-21. PMID: 22007515.

Hung WC, Chang HC. Indole-3-carbinol inhibits Sp1-induced matrix metalloproteinase-2 expression to attenuate migration and invasion of breast cancer cells. J Agric Food Chem. 2009 Jan 14;57(1):76-82. PMID: 19061309.

Kunimasa K, Kobayashi T, Sugiyama S, et al. Indole-3-carbinol suppresses tumor-induced angiogenesis by inhibiting tube formation and inducing apoptosis. Biosci Biotechnol Biochem. 2008 Aug;72(8):2243-6. PMID: 18685185.

Morshedi D, Rezaei-Ghaleh N, Ebrahim-Habibi A, et al. Inhibition of amyloid fibrillation of lysozyme by indole derivatives--possible mechanism of action. FEBS J. 2007 Dec;274(24):6415-25. PMID: 18028426.

" Xi Not dangerous goods.

LKT I5213 Indole-3-carbinol 25 g 230.6 Indole, glucosinolate found in cruciferous vegetables. 3-Indomethanol; 3-Hydroxymethylindole; 3-Indolyl- carbinol 700-06-1 ≥98% 147.17 C9H9NO C1=CC=C2C(=C1)C(=CN2)CO Ambient -20°C Slightly soluble in cold water. "Choi HS, Jeon HJ, Lee OH, et al. Indole-3-carbinol, a vegetable phytochemical, inhibits adipogenesis by regulating cell cycle and AMPKα signaling. Biochimie. 2014 Sep;104:127-36. PMID: 24952351.

Mao CG, Tao ZZ, Chen Z, et al. Indole-3-carbinol inhibits nasopharyngeal carcinoma cell growth in vivo and in vitro through inhibition of the PI3K/Akt pathway. Exp Ther Med. 2014 Jul;8(1):207-12. PMID: 24944623.

Ping J, Gao AM, Xu D, et al. Therapeutic effect of indole-3-carbinol on pig serum-induced hepatic fibrosis in rats. Yao Xue Xue Bao. 2011 Aug;46(8):915-21. PMID: 22007515.

Hung WC, Chang HC. Indole-3-carbinol inhibits Sp1-induced matrix metalloproteinase-2 expression to attenuate migration and invasion of breast cancer cells. J Agric Food Chem. 2009 Jan 14;57(1):76-82. PMID: 19061309.

Kunimasa K, Kobayashi T, Sugiyama S, et al. Indole-3-carbinol suppresses tumor-induced angiogenesis by inhibiting tube formation and inducing apoptosis. Biosci Biotechnol Biochem. 2008 Aug;72(8):2243-6. PMID: 18685185.

Morshedi D, Rezaei-Ghaleh N, Ebrahim-Habibi A, et al. Inhibition of amyloid fibrillation of lysozyme by indole derivatives--possible mechanism of action. FEBS J. 2007 Dec;274(24):6415-25. PMID: 18028426.

" Xi Not dangerous goods.

LKT I5215 Indolicidin 0.5 mg 180 Antimicrobial peptide. 140896-21-5 ≥95% 1906.33 C100H132N26O13 CCC(C)C(C(=O)NC(CC(C)C)C(=O)N1CCCC1C(=O)NC(CC2=CNC3=CC=CC=C32)C(=O)NC(CCCCN)C(=O)NC(CC4=CNC5=CC=CC=C54)C(=O)N6CCCC6C(=O)NC(CC7=CNC8=CC=CC=C87)C(=O)NC(CC9=CNC1=CC=CC=C19)C(=O)N1CCCC1C(=O)NC(CC1=CNC2=CC=CC=C21)C(=O)NC(CCCNC(=N)N)C(=O)NC(CCCNC(=N)N)C(=O)N)N Ambient -20°C "Vila-Farres X, Garcia de la Maria C, López-Rojas R, et al. In vitro activity of several antimicrobial peptides against colistin-susceptible and colistin-resistant Acinetobacter baumannii. Clin Microbiol Infect. 2012 Apr;18(4):383-7. PMID: 21672084.

Végh AG, Nagy K, Bálint Z, et al. Effect of antimicrobial peptide-amide: indolicidin on biological membranes. J Biomed Biotechnol. 2011;2011:670589. PMID: 21765635.

Rieg S, Kaasch AJ, Wehrle J, et al. Susceptibility of clinical Staphylococcus aureus isolates to innate defense antimicrobial peptides. Microbes Infect. 2011 Aug;13(8-9):761-5. PMID: 21473929.

Rokitskaya TI, Kolodkin NI, Kotova EA, et al. Indolicidin action on membrane permeability: carrier mechanism versus pore formation. Biochim Biophys Acta. 2011 Jan;1808(1):91-7. PMID: 20851098.

Rieg S, Meier B, Fähnrich E, et al. Differential activity of innate defense antimicrobial peptides against Nocardia species. BMC Microbiol. 2010 Feb 23;10:61. PMID: 20178618.

Nan YH, Park KH, Park Y, et al. Investigating the effects of positive charge and hydrophobicity on the cell selectivity, mechanism of action and anti-inflammatory activity of a Trp-rich antimicrobial peptide indolicidin. FEMS Microbiol Lett. 2009 Mar;292(1):134-40. PMID: 19191872.

Bowdish DM, Davidson DJ, Scott MG, et al. Immunomodulatory activities of small host defense peptides. Antimicrob Agents Chemother. 2005 May;49(5):1727-32. PMID: 15855488.

" Not dangerous goods.

LKT I5215 Indolicidin 1 mg 306.1 Antimicrobial peptide. 140896-21-5 ≥95% 1906.33 C100H132N26O13 CCC(C)C(C(=O)NC(CC(C)C)C(=O)N1CCCC1C(=O)NC(CC2=CNC3=CC=CC=C32)C(=O)NC(CCCCN)C(=O)NC(CC4=CNC5=CC=CC=C54)C(=O)N6CCCC6C(=O)NC(CC7=CNC8=CC=CC=C87)C(=O)NC(CC9=CNC1=CC=CC=C19)C(=O)N1CCCC1C(=O)NC(CC1=CNC2=CC=CC=C21)C(=O)NC(CCCNC(=N)N)C(=O)NC(CCCNC(=N)N)C(=O)N)N Ambient -20°C "Vila-Farres X, Garcia de la Maria C, López-Rojas R, et al. In vitro activity of several antimicrobial peptides against colistin-susceptible and colistin-resistant Acinetobacter baumannii. Clin Microbiol Infect. 2012 Apr;18(4):383-7. PMID: 21672084.

Végh AG, Nagy K, Bálint Z, et al. Effect of antimicrobial peptide-amide: indolicidin on biological membranes. J Biomed Biotechnol. 2011;2011:670589. PMID: 21765635.

Rieg S, Kaasch AJ, Wehrle J, et al. Susceptibility of clinical Staphylococcus aureus isolates to innate defense antimicrobial peptides. Microbes Infect. 2011 Aug;13(8-9):761-5. PMID: 21473929.

Rokitskaya TI, Kolodkin NI, Kotova EA, et al. Indolicidin action on membrane permeability: carrier mechanism versus pore formation. Biochim Biophys Acta. 2011 Jan;1808(1):91-7. PMID: 20851098.

Rieg S, Meier B, Fähnrich E, et al. Differential activity of innate defense antimicrobial peptides against Nocardia species. BMC Microbiol. 2010 Feb 23;10:61. PMID: 20178618.

Nan YH, Park KH, Park Y, et al. Investigating the effects of positive charge and hydrophobicity on the cell selectivity, mechanism of action and anti-inflammatory activity of a Trp-rich antimicrobial peptide indolicidin. FEMS Microbiol Lett. 2009 Mar;292(1):134-40. PMID: 19191872.

Bowdish DM, Davidson DJ, Scott MG, et al. Immunomodulatory activities of small host defense peptides. Antimicrob Agents Chemother. 2005 May;49(5):1727-32. PMID: 15855488.

" Not dangerous goods.

LKT I5215 Indolicidin 2.5 mg 540 Antimicrobial peptide. 140896-21-5 ≥95% 1906.33 C100H132N26O13 CCC(C)C(C(=O)NC(CC(C)C)C(=O)N1CCCC1C(=O)NC(CC2=CNC3=CC=CC=C32)C(=O)NC(CCCCN)C(=O)NC(CC4=CNC5=CC=CC=C54)C(=O)N6CCCC6C(=O)NC(CC7=CNC8=CC=CC=C87)C(=O)NC(CC9=CNC1=CC=CC=C19)C(=O)N1CCCC1C(=O)NC(CC1=CNC2=CC=CC=C21)C(=O)NC(CCCNC(=N)N)C(=O)NC(CCCNC(=N)N)C(=O)N)N Ambient -20°C "Vila-Farres X, Garcia de la Maria C, López-Rojas R, et al. In vitro activity of several antimicrobial peptides against colistin-susceptible and colistin-resistant Acinetobacter baumannii. Clin Microbiol Infect. 2012 Apr;18(4):383-7. PMID: 21672084.

Végh AG, Nagy K, Bálint Z, et al. Effect of antimicrobial peptide-amide: indolicidin on biological membranes. J Biomed Biotechnol. 2011;2011:670589. PMID: 21765635.

Rieg S, Kaasch AJ, Wehrle J, et al. Susceptibility of clinical Staphylococcus aureus isolates to innate defense antimicrobial peptides. Microbes Infect. 2011 Aug;13(8-9):761-5. PMID: 21473929.

Rokitskaya TI, Kolodkin NI, Kotova EA, et al. Indolicidin action on membrane permeability: carrier mechanism versus pore formation. Biochim Biophys Acta. 2011 Jan;1808(1):91-7. PMID: 20851098.

Rieg S, Meier B, Fähnrich E, et al. Differential activity of innate defense antimicrobial peptides against Nocardia species. BMC Microbiol. 2010 Feb 23;10:61. PMID: 20178618.

Nan YH, Park KH, Park Y, et al. Investigating the effects of positive charge and hydrophobicity on the cell selectivity, mechanism of action and anti-inflammatory activity of a Trp-rich antimicrobial peptide indolicidin. FEMS Microbiol Lett. 2009 Mar;292(1):134-40. PMID: 19191872.

Bowdish DM, Davidson DJ, Scott MG, et al. Immunomodulatory activities of small host defense peptides. Antimicrob Agents Chemother. 2005 May;49(5):1727-32. PMID: 15855488.

" Not dangerous goods.

LKT I5315 Indomethacin 5 g 38.8 NSAID; COX-1/2 inhibitor. 1-(4-Chlorobenzoyl)-5-methoxy-2-methyl-1H-indole- 3-acetic acid Amuno; Idomethine. 53-86-1 ≥98% 357.79 C19H16ClNO4 CC1=C(C2=C(N1C(=O)C3=CC=C(C=C3)Cl)C=CC(=C2)OC)CC(=O)O Ambient Ambient Insoluble in water.  Soluble in ethanol (20 mg/mL), or acetone. "Adewoye EO, Salami AT. Anti-ulcerogenic mechanism of magnesium in indomethacin induced gastric ulcer in rats. Niger J Physiol Sci. 2013 Dec 20;28(2):193-9. PMID: 24937396.

Guo YC, Chang CM, Hsu WL, et al. Indomethacin inhibits cancer cell migration via attenuation of cellular calcium mobilization. Molecules. 2013 Jun 4;18(6):6584-96. PMID: 23736792.

Summ O, Evers S. Mechanism of action of indomethacin in indomethacin-responsive headaches. Curr Pain Headache Rep. 2013 Apr;17(4):327. PMID: 23423598.

Giles W, Bisits A. Preterm labour. The present and future of tocolysis. Best Pract Res Clin Obstet Gynaecol. 2007 Oct;21(5):857-68. PMID: 17459777.

Li W, Li J, Ashok M, et al. A cardiovascular drug rescues mice from lethal sepsis by selectively attentuating a late-acting proinflammatory mediator, high mobility group box 1. J Immunol. 2007 Mar 15;178(6):3856-3864. PMID: 17339485.

" T+ "UN number: 2811     Class: 6.1     Packing Group: I

Proper shipping name:  Toxic solids, organic, n.o.s. (Indomethacin)

Marine pollutant:  No; Poison inhalation hazard:  No "

LKT I5315 Indomethacin 10 g 71.2 NSAID; COX-1/2 inhibitor. 1-(4-Chlorobenzoyl)-5-methoxy-2-methyl-1H-indole- 3-acetic acid Amuno; Idomethine. 53-86-1 ≥98% 357.79 C19H16ClNO4 CC1=C(C2=C(N1C(=O)C3=CC=C(C=C3)Cl)C=CC(=C2)OC)CC(=O)O Ambient Ambient Insoluble in water.  Soluble in ethanol (20 mg/mL), or acetone. "Adewoye EO, Salami AT. Anti-ulcerogenic mechanism of magnesium in indomethacin induced gastric ulcer in rats. Niger J Physiol Sci. 2013 Dec 20;28(2):193-9. PMID: 24937396.

Guo YC, Chang CM, Hsu WL, et al. Indomethacin inhibits cancer cell migration via attenuation of cellular calcium mobilization. Molecules. 2013 Jun 4;18(6):6584-96. PMID: 23736792.

Summ O, Evers S. Mechanism of action of indomethacin in indomethacin-responsive headaches. Curr Pain Headache Rep. 2013 Apr;17(4):327. PMID: 23423598.

Giles W, Bisits A. Preterm labour. The present and future of tocolysis. Best Pract Res Clin Obstet Gynaecol. 2007 Oct;21(5):857-68. PMID: 17459777.

Li W, Li J, Ashok M, et al. A cardiovascular drug rescues mice from lethal sepsis by selectively attentuating a late-acting proinflammatory mediator, high mobility group box 1. J Immunol. 2007 Mar 15;178(6):3856-3864. PMID: 17339485.

" T+ "UN number: 2811     Class: 6.1     Packing Group: I

Proper shipping name:  Toxic solids, organic, n.o.s. (Indomethacin)

Marine pollutant:  No; Poison inhalation hazard:  No "

LKT I5315 Indomethacin 25 g 126.9 NSAID; COX-1/2 inhibitor. 1-(4-Chlorobenzoyl)-5-methoxy-2-methyl-1H-indole- 3-acetic acid Amuno; Idomethine. 53-86-1 ≥98% 357.79 C19H16ClNO4 CC1=C(C2=C(N1C(=O)C3=CC=C(C=C3)Cl)C=CC(=C2)OC)CC(=O)O Ambient Ambient Insoluble in water.  Soluble in ethanol (20 mg/mL), or acetone. "Adewoye EO, Salami AT. Anti-ulcerogenic mechanism of magnesium in indomethacin induced gastric ulcer in rats. Niger J Physiol Sci. 2013 Dec 20;28(2):193-9. PMID: 24937396.

Guo YC, Chang CM, Hsu WL, et al. Indomethacin inhibits cancer cell migration via attenuation of cellular calcium mobilization. Molecules. 2013 Jun 4;18(6):6584-96. PMID: 23736792.

Summ O, Evers S. Mechanism of action of indomethacin in indomethacin-responsive headaches. Curr Pain Headache Rep. 2013 Apr;17(4):327. PMID: 23423598.

Giles W, Bisits A. Preterm labour. The present and future of tocolysis. Best Pract Res Clin Obstet Gynaecol. 2007 Oct;21(5):857-68. PMID: 17459777.

Li W, Li J, Ashok M, et al. A cardiovascular drug rescues mice from lethal sepsis by selectively attentuating a late-acting proinflammatory mediator, high mobility group box 1. J Immunol. 2007 Mar 15;178(6):3856-3864. PMID: 17339485.

" T+ "UN number: 2811     Class: 6.1     Packing Group: I

Proper shipping name:  Toxic solids, organic, n.o.s. (Indomethacin)

Marine pollutant:  No; Poison inhalation hazard:  No "

LKT I5315 Indomethacin 100 g 283.1 NSAID; COX-1/2 inhibitor. 1-(4-Chlorobenzoyl)-5-methoxy-2-methyl-1H-indole- 3-acetic acid Amuno; Idomethine. 53-86-1 ≥98% 357.79 C19H16ClNO4 CC1=C(C2=C(N1C(=O)C3=CC=C(C=C3)Cl)C=CC(=C2)OC)CC(=O)O Ambient Ambient Insoluble in water.  Soluble in ethanol (20 mg/mL), or acetone. "Adewoye EO, Salami AT. Anti-ulcerogenic mechanism of magnesium in indomethacin induced gastric ulcer in rats. Niger J Physiol Sci. 2013 Dec 20;28(2):193-9. PMID: 24937396.

Guo YC, Chang CM, Hsu WL, et al. Indomethacin inhibits cancer cell migration via attenuation of cellular calcium mobilization. Molecules. 2013 Jun 4;18(6):6584-96. PMID: 23736792.

Summ O, Evers S. Mechanism of action of indomethacin in indomethacin-responsive headaches. Curr Pain Headache Rep. 2013 Apr;17(4):327. PMID: 23423598.

Giles W, Bisits A. Preterm labour. The present and future of tocolysis. Best Pract Res Clin Obstet Gynaecol. 2007 Oct;21(5):857-68. PMID: 17459777.

Li W, Li J, Ashok M, et al. A cardiovascular drug rescues mice from lethal sepsis by selectively attentuating a late-acting proinflammatory mediator, high mobility group box 1. J Immunol. 2007 Mar 15;178(6):3856-3864. PMID: 17339485.

" T+ "UN number: 2811     Class: 6.1     Packing Group: I

Proper shipping name:  Toxic solids, organic, n.o.s. (Indomethacin)

Marine pollutant:  No; Poison inhalation hazard:  No "

LKT I5357 Inositol 100 g 55 Endogenous sugar produced from glucose, required for production of IMP and phosphatidyl inositol. myo-Inositol; i-Inositol; Cyclohexanehexol; Meat sugar; Phaseomannite; Dambose; Mouse antialopecia factor 6917-35-7 ≥98% 180.16 C6H12O6 C1(C(C(C(C(C1O)O)O)O)O)O Ambient Ambient Soluble in water. Slightly soluble in alcohol. Insoluble in common organic solvents. "Michell RH. Inositol lipids: from an archaeal origin to phosphatidylinositol 3,5-bisphosphate faults in human disease. FEBS J. 2013 Dec;280(24):6281-94. PMID: 23902363.

Larner J, Brautigan DL, Thorner MO. D-chiro-inositol glycans in insulin signaling and insulin resistance. Mol Med. 2010 Nov-Dec;16(11-12):543-52. PMID: 20811656.

Shen X, Xiao H, Ranallo R, et al. Modulation of ATP-dependent chromatin-remodeling complexes by inositol polyphosphates. Science. 2003 Jan 3;299(5603):112-4. PMID: 12434013.

Rapiejko PJ, Northup JK, Evans T, et al. G-proteins of fat-cells. Role in hormonal regulation of intracellular inositol 1,4,5-trisphosphate. Biochem J. 1986 Nov 15;240(1):35-40. PMID: 3103610.

" Not dangerous goods.

LKT I5357 Inositol 500 g 212.8 Endogenous sugar produced from glucose, required for production of IMP and phosphatidyl inositol. myo-Inositol; i-Inositol; Cyclohexanehexol; Meat sugar; Phaseomannite; Dambose; Mouse antialopecia factor 6917-35-7 ≥98% 180.16 C6H12O6 C1(C(C(C(C(C1O)O)O)O)O)O Ambient Ambient Soluble in water. Slightly soluble in alcohol. Insoluble in common organic solvents. "Michell RH. Inositol lipids: from an archaeal origin to phosphatidylinositol 3,5-bisphosphate faults in human disease. FEBS J. 2013 Dec;280(24):6281-94. PMID: 23902363.

Larner J, Brautigan DL, Thorner MO. D-chiro-inositol glycans in insulin signaling and insulin resistance. Mol Med. 2010 Nov-Dec;16(11-12):543-52. PMID: 20811656.

Shen X, Xiao H, Ranallo R, et al. Modulation of ATP-dependent chromatin-remodeling complexes by inositol polyphosphates. Science. 2003 Jan 3;299(5603):112-4. PMID: 12434013.

Rapiejko PJ, Northup JK, Evans T, et al. G-proteins of fat-cells. Role in hormonal regulation of intracellular inositol 1,4,5-trisphosphate. Biochem J. 1986 Nov 15;240(1):35-40. PMID: 3103610.

" Not dangerous goods.

LKT I5414 Indapamide 250 mg 47.6 Thiazide-like diuretic; Kv7.1 and minK K+ channel blocker. 3-(Aminosulfonyl)-4-chloro-NN-(2,3-dihydro-2-methyl-1H-indol-1-yl)benzamide S-1520; Bajaten; Fludex; Indamol; Lozol; Natrilix; Veroxil 26807-65-8 ≥98% 365.84 C16H16ClN3O3S CC1CC2=CC=CC=C2N1NC(=O)C3=CC(=C(C=C3)Cl)S(=O)(=O)N Ambient Ambient Soluble in methanol, acetic acid and ethyl acetate. Slightly soluble in chloroform. "Janega P, Kojsová S, Jendeková L, et al. Indapamide-induced prevention of myocardial fibrosis in spontaneous hypertension rats is not nitric oxide-related. Physiol Res. 2007;56(6):825-8. PMID: 18197750.

Letsas KP, Alexanian IP, Pappas LK, et al. QT interval prolongation and torsade de pointes associated with indapamide. Int J Cardiol. 2006 Oct 10;112(3):373-4. PMID: 16260053.

Peng H, Zhou Z, Zhao W, et al. Study on the antidiuretic efficacy and mechanism of indapamide in central diabetes insipidus. Hunan Yi Ke Da Xue Xue Bao. 1999;24(3):259-62. PMID: 12016800.

" Not dangerous goods.

LKT I5414 Indapamide 1 g 61.1 Thiazide-like diuretic; Kv7.1 and minK K+ channel blocker. 3-(Aminosulfonyl)-4-chloro-NN-(2,3-dihydro-2-methyl-1H-indol-1-yl)benzamide S-1520; Bajaten; Fludex; Indamol; Lozol; Natrilix; Veroxil 26807-65-8 ≥98% 365.84 C16H16ClN3O3S CC1CC2=CC=CC=C2N1NC(=O)C3=CC(=C(C=C3)Cl)S(=O)(=O)N Ambient Ambient Soluble in methanol, acetic acid and ethyl acetate. Slightly soluble in chloroform. "Janega P, Kojsová S, Jendeková L, et al. Indapamide-induced prevention of myocardial fibrosis in spontaneous hypertension rats is not nitric oxide-related. Physiol Res. 2007;56(6):825-8. PMID: 18197750.

Letsas KP, Alexanian IP, Pappas LK, et al. QT interval prolongation and torsade de pointes associated with indapamide. Int J Cardiol. 2006 Oct 10;112(3):373-4. PMID: 16260053.

Peng H, Zhou Z, Zhao W, et al. Study on the antidiuretic efficacy and mechanism of indapamide in central diabetes insipidus. Hunan Yi Ke Da Xue Xue Bao. 1999;24(3):259-62. PMID: 12016800.

" Not dangerous goods.

LKT I5414 Indapamide 5 g 203.8 Thiazide-like diuretic; Kv7.1 and minK K+ channel blocker. 3-(Aminosulfonyl)-4-chloro-NN-(2,3-dihydro-2-methyl-1H-indol-1-yl)benzamide S-1520; Bajaten; Fludex; Indamol; Lozol; Natrilix; Veroxil 26807-65-8 ≥98% 365.84 C16H16ClN3O3S CC1CC2=CC=CC=C2N1NC(=O)C3=CC(=C(C=C3)Cl)S(=O)(=O)N Ambient Ambient Soluble in methanol, acetic acid and ethyl acetate. Slightly soluble in chloroform. "Janega P, Kojsová S, Jendeková L, et al. Indapamide-induced prevention of myocardial fibrosis in spontaneous hypertension rats is not nitric oxide-related. Physiol Res. 2007;56(6):825-8. PMID: 18197750.

Letsas KP, Alexanian IP, Pappas LK, et al. QT interval prolongation and torsade de pointes associated with indapamide. Int J Cardiol. 2006 Oct 10;112(3):373-4. PMID: 16260053.

Peng H, Zhou Z, Zhao W, et al. Study on the antidiuretic efficacy and mechanism of indapamide in central diabetes insipidus. Hunan Yi Ke Da Xue Xue Bao. 1999;24(3):259-62. PMID: 12016800.

" Not dangerous goods.

LKT I5476 Interleukin-6 Receptor Fragment 0.5 mg 120 Peptide, IL-6 receptor fragment. IL-6R ≥95% 1216.32 C51H85N13O21 Ambient -20°C Bosze S, Hudecz F, Igaz P, et al. Interleukin-6 N-terminal peptides modulate the expression of junB protooncogene and the production of fibrinogen in HepG2 cells. Biol Chem. 2003 Mar;384(3):409-21. PMID: 12715892. Not dangerous goods.

LKT I5476 Interleukin-6 Receptor Fragment 1 mg 204.1 Peptide, IL-6 receptor fragment. IL-6R ≥95% 1216.32 C51H85N13O21 Ambient -20°C Bosze S, Hudecz F, Igaz P, et al. Interleukin-6 N-terminal peptides modulate the expression of junB protooncogene and the production of fibrinogen in HepG2 cells. Biol Chem. 2003 Mar;384(3):409-21. PMID: 12715892. Not dangerous goods.

LKT I5476 Interleukin-6 Receptor Fragment 2.5 mg 359.9 Peptide, IL-6 receptor fragment. IL-6R ≥95% 1216.32 C51H85N13O21 Ambient -20°C Bosze S, Hudecz F, Igaz P, et al. Interleukin-6 N-terminal peptides modulate the expression of junB protooncogene and the production of fibrinogen in HepG2 cells. Biol Chem. 2003 Mar;384(3):409-21. PMID: 12715892. Not dangerous goods.

LKT I5753 Ionomycin Calcium 1 mg 37.5 Polyether Ca2+ ionophore. ATCC 31005 56092-82-1 ≥98% 747.07 C41H70O9 Ca CC(CCC(=O)[O-])CC(C)CC(C)C(=O)C=C(C(C)CC(C)CC=CC(C)C(C(C)C(CC1CCC(O1)(C)C2CCC(O2)(C)C(C)O)O)O)[O-].[Ca+2] Protect from light. Ambient 4°C "Soluble in ethanol to 100mM,  DMSO to 25mM.

5mg/ml in methanol  " "Müller MS, Obel LF, Waagepetersen HS, et al. Complex actions of ionomycin in cultured cerebellar astrocytes affecting both calcium-induced calcium release and store-operated calcium entry. Neurochem Res. 2013 Jun;38(6):1260-5. PMID: 23519933.

Dedkova EN, Sigova AA, Zinchenko VP. Mechanism of action of calcium ionophores on intact cells: ionophore-resistant cells. Membr Cell Biol. 2000;13(3):357-68. PMID: 10768486

Reynolds JE, Eastman A. Intracellular calcium stores are not required for Bcl-2-mediated protection from apoptosis. J Biol Chem. 1996 Nov 1;271(44):27739-43. PMID: 8910367.

Mason MJ, Grinstein S. Ionomycin activates electrogenic Ca2+ influx in rat thymic lymphocytes. Biochem J. 1993 Nov 15;296 ( Pt 1):33-9. PMID: 8250855.

" Xn Not dangerous goods.

LKT I5753 Ionomycin Calcium 5 mg 112.5 Polyether Ca2+ ionophore. ATCC 31005 56092-82-1 ≥98% 747.07 C41H70O9 Ca CC(CCC(=O)[O-])CC(C)CC(C)C(=O)C=C(C(C)CC(C)CC=CC(C)C(C(C)C(CC1CCC(O1)(C)C2CCC(O2)(C)C(C)O)O)O)[O-].[Ca+2] Protect from light. Ambient 4°C "Soluble in ethanol to 100mM,  DMSO to 25mM.

5mg/ml in methanol  " "Müller MS, Obel LF, Waagepetersen HS, et al. Complex actions of ionomycin in cultured cerebellar astrocytes affecting both calcium-induced calcium release and store-operated calcium entry. Neurochem Res. 2013 Jun;38(6):1260-5. PMID: 23519933.

Dedkova EN, Sigova AA, Zinchenko VP. Mechanism of action of calcium ionophores on intact cells: ionophore-resistant cells. Membr Cell Biol. 2000;13(3):357-68. PMID: 10768486

Reynolds JE, Eastman A. Intracellular calcium stores are not required for Bcl-2-mediated protection from apoptosis. J Biol Chem. 1996 Nov 1;271(44):27739-43. PMID: 8910367.

Mason MJ, Grinstein S. Ionomycin activates electrogenic Ca2+ influx in rat thymic lymphocytes. Biochem J. 1993 Nov 15;296 ( Pt 1):33-9. PMID: 8250855.

" Xn Not dangerous goods.

LKT I5830 Iohexol 1 g 67.9 Low osmolarity contrast agent used for imaging procedures. 5-[Acetyl(2,3-dihydroxypropyl)amino]-N,N'-bis(2,3-dihydroxypropyl)-2,4,6-triiodo-1,3-benzenedicarboxamid Win-39424; Omnepaque; Exypaque 66108-95-0 ≥98% 821.14 C19H26I3N3O9 CC(=O)N(CC(CO)O)C1=C(C(=C(C(=C1I)C(=O)NCC(CO)O)I)C(=O)NCC(CO)O)I Stable in aqueous solutions. Ambient Ambient Soluble in water. McCormack PL. Iobitridol: a review of its use as a contrast medium in diagnostic imaging. Clin Drug Investig. 2013 Feb;33(2):155-66. PMID: 23341290. None Not dangerous goods.

LKT I5830 Iohexol 5 g 271.7 Low osmolarity contrast agent used for imaging procedures. 5-[Acetyl(2,3-dihydroxypropyl)amino]-N,N'-bis(2,3-dihydroxypropyl)-2,4,6-triiodo-1,3-benzenedicarboxamid Win-39424; Omnepaque; Exypaque 66108-95-0 ≥98% 821.14 C19H26I3N3O9 CC(=O)N(CC(CO)O)C1=C(C(=C(C(=C1I)C(=O)NCC(CO)O)I)C(=O)NCC(CO)O)I Stable in aqueous solutions. Ambient Ambient Soluble in water. McCormack PL. Iobitridol: a review of its use as a contrast medium in diagnostic imaging. Clin Drug Investig. 2013 Feb;33(2):155-66. PMID: 23341290. None Not dangerous goods.

LKT I5830 Iohexol 25 g 815.4 Low osmolarity contrast agent used for imaging procedures. 5-[Acetyl(2,3-dihydroxypropyl)amino]-N,N'-bis(2,3-dihydroxypropyl)-2,4,6-triiodo-1,3-benzenedicarboxamid Win-39424; Omnepaque; Exypaque 66108-95-0 ≥98% 821.14 C19H26I3N3O9 CC(=O)N(CC(CO)O)C1=C(C(=C(C(=C1I)C(=O)NCC(CO)O)I)C(=O)NCC(CO)O)I Stable in aqueous solutions. Ambient Ambient Soluble in water. McCormack PL. Iobitridol: a review of its use as a contrast medium in diagnostic imaging. Clin Drug Investig. 2013 Feb;33(2):155-66. PMID: 23341290. None Not dangerous goods.

LKT I6068 Ipriflavone 1 g 38.9 Synthetic isoflavone. 7-(1-Methylethoxy)-3-phenyl-4H-1-benzopyran-4-one Iprosten; Osten; Osteofix; Yambolap 35212-22-7 ≥98% 280.32 C18H16O3 CC(C)OC1=CC2=C(C=C1)C(=O)C(=CO2)C3=CC=CC=C3 Ambient Ambient Poor solubility in water. "Lv WT, Yang YH, Ma LQ, et al. Ipriflavone reverses the adverse effects of a low-calcium diet on the histology of the tibia in caged layers. Br Poult Sci. 2014;55(2):207-14. PMID: 24404906.

Delarmelina JM, Dutra JC, Batitucci Mdo C. Antimutagenic activity of ipriflavone against the DNA-damage induced by cyclophosphamide in mice. Food Chem Toxicol. 2014 Mar;65:140-6. PMID: 24389340.

" None Not dangerous goods.

LKT I6068 Ipriflavone 5 g 91 Synthetic isoflavone. 7-(1-Methylethoxy)-3-phenyl-4H-1-benzopyran-4-one Iprosten; Osten; Osteofix; Yambolap 35212-22-7 ≥98% 280.32 C18H16O3 CC(C)OC1=CC2=C(C=C1)C(=O)C(=CO2)C3=CC=CC=C3 Ambient Ambient Poor solubility in water. "Lv WT, Yang YH, Ma LQ, et al. Ipriflavone reverses the adverse effects of a low-calcium diet on the histology of the tibia in caged layers. Br Poult Sci. 2014;55(2):207-14. PMID: 24404906.

Delarmelina JM, Dutra JC, Batitucci Mdo C. Antimutagenic activity of ipriflavone against the DNA-damage induced by cyclophosphamide in mice. Food Chem Toxicol. 2014 Mar;65:140-6. PMID: 24389340.

" None Not dangerous goods.

LKT I6068 Ipriflavone 10 g 176 Synthetic isoflavone. 7-(1-Methylethoxy)-3-phenyl-4H-1-benzopyran-4-one Iprosten; Osten; Osteofix; Yambolap 35212-22-7 ≥98% 280.32 C18H16O3 CC(C)OC1=CC2=C(C=C1)C(=O)C(=CO2)C3=CC=CC=C3 Ambient Ambient Poor solubility in water. "Lv WT, Yang YH, Ma LQ, et al. Ipriflavone reverses the adverse effects of a low-calcium diet on the histology of the tibia in caged layers. Br Poult Sci. 2014;55(2):207-14. PMID: 24404906.

Delarmelina JM, Dutra JC, Batitucci Mdo C. Antimutagenic activity of ipriflavone against the DNA-damage induced by cyclophosphamide in mice. Food Chem Toxicol. 2014 Mar;65:140-6. PMID: 24389340.

" None Not dangerous goods.

LKT I6932 Irinotecan 5 mg 47.6 Camptothecin analog; topoisomerase I inhibitor, potential AChE inhibitor. [1,4'-Bipiperidine]-1'-carboxylic acid (4S)-4,11- diethyl-3,4,12,14-tetrahydro-4-hydroxy-3,14-dioxo- 1H-pyrano[3',4':6,7]indolizino[1,2-b]quinolin-9-yl ester 97682-44-5 ≥98% 586.68 C33H38N4O6 CCC1=C2C=C(C=CC2=NC3=C1CN4C3=CC5=C(C4=O)COC(=O)C5(CC)O)OC(=O)N6CCC(CC6)N7CCCCC7 Ambient 4°C Insoluble in water.  Soluble in DMSO "Hu J, Kinn J, Zirakzadeh AA, et al. The effects of chemotherapeutic drugs on human monocyte-derived dendritic cell differentiation and antigen presentation. Clin Exp Immunol. 2013 Jun;172(3):490-9. PMID: 23600838.

Pan P, Li Y, Yu H, et al. Molecular principle of topotecan resistance by topoisomerase I mutations through molecular modeling approaches. J Chem Inf Model. 2013 Apr 22;53(4):997-1006. PMID: 23521602.

Chen AY, Chen PM, Chen YJ. DNA topoisomerase I drugs and radiotherapy for lung cancer. J Thorac Dis. 2012 Aug;4(4):390-7. PMID: 22934142.

Chintala S, Tóth K, Cao S, et al. Se-methylselenocysteine sensitizes hypoxic tumor cells to irinotecan by targeting hypoxia-inducible factor 1alpha. Cancer Chemother Pharmacol. 2010 Oct;66(5):899-911. PMID: 20066420.

Dodds HM, Rivory LP. The mechanism for the inhibition of acetylcholinesterases by irinotecan (CPT-11). Mol Pharmacol. 1999 Dec;56(6):1346-53. PMID: 10570064." Xn Not dangerous goods.

LKT I6932 Irinotecan 10 mg 67.9 Camptothecin analog; topoisomerase I inhibitor, potential AChE inhibitor. [1,4'-Bipiperidine]-1'-carboxylic acid (4S)-4,11- diethyl-3,4,12,14-tetrahydro-4-hydroxy-3,14-dioxo- 1H-pyrano[3',4':6,7]indolizino[1,2-b]quinolin-9-yl ester 97682-44-5 ≥98% 586.68 C33H38N4O6 CCC1=C2C=C(C=CC2=NC3=C1CN4C3=CC5=C(C4=O)COC(=O)C5(CC)O)OC(=O)N6CCC(CC6)N7CCCCC7 Ambient 4°C Insoluble in water.  Soluble in DMSO "Hu J, Kinn J, Zirakzadeh AA, et al. The effects of chemotherapeutic drugs on human monocyte-derived dendritic cell differentiation and antigen presentation. Clin Exp Immunol. 2013 Jun;172(3):490-9. PMID: 23600838.

Pan P, Li Y, Yu H, et al. Molecular principle of topotecan resistance by topoisomerase I mutations through molecular modeling approaches. J Chem Inf Model. 2013 Apr 22;53(4):997-1006. PMID: 23521602.

Chen AY, Chen PM, Chen YJ. DNA topoisomerase I drugs and radiotherapy for lung cancer. J Thorac Dis. 2012 Aug;4(4):390-7. PMID: 22934142.

Chintala S, Tóth K, Cao S, et al. Se-methylselenocysteine sensitizes hypoxic tumor cells to irinotecan by targeting hypoxia-inducible factor 1alpha. Cancer Chemother Pharmacol. 2010 Oct;66(5):899-911. PMID: 20066420.

Dodds HM, Rivory LP. The mechanism for the inhibition of acetylcholinesterases by irinotecan (CPT-11). Mol Pharmacol. 1999 Dec;56(6):1346-53. PMID: 10570064." Xn Not dangerous goods.

LKT I6932 Irinotecan 25 mg 101.9 Camptothecin analog; topoisomerase I inhibitor, potential AChE inhibitor. [1,4'-Bipiperidine]-1'-carboxylic acid (4S)-4,11- diethyl-3,4,12,14-tetrahydro-4-hydroxy-3,14-dioxo- 1H-pyrano[3',4':6,7]indolizino[1,2-b]quinolin-9-yl ester 97682-44-5 ≥98% 586.68 C33H38N4O6 CCC1=C2C=C(C=CC2=NC3=C1CN4C3=CC5=C(C4=O)COC(=O)C5(CC)O)OC(=O)N6CCC(CC6)N7CCCCC7 Ambient 4°C Insoluble in water.  Soluble in DMSO "Hu J, Kinn J, Zirakzadeh AA, et al. The effects of chemotherapeutic drugs on human monocyte-derived dendritic cell differentiation and antigen presentation. Clin Exp Immunol. 2013 Jun;172(3):490-9. PMID: 23600838.

Pan P, Li Y, Yu H, et al. Molecular principle of topotecan resistance by topoisomerase I mutations through molecular modeling approaches. J Chem Inf Model. 2013 Apr 22;53(4):997-1006. PMID: 23521602.

Chen AY, Chen PM, Chen YJ. DNA topoisomerase I drugs and radiotherapy for lung cancer. J Thorac Dis. 2012 Aug;4(4):390-7. PMID: 22934142.

Chintala S, Tóth K, Cao S, et al. Se-methylselenocysteine sensitizes hypoxic tumor cells to irinotecan by targeting hypoxia-inducible factor 1alpha. Cancer Chemother Pharmacol. 2010 Oct;66(5):899-911. PMID: 20066420.

Dodds HM, Rivory LP. The mechanism for the inhibition of acetylcholinesterases by irinotecan (CPT-11). Mol Pharmacol. 1999 Dec;56(6):1346-53. PMID: 10570064." Xn Not dangerous goods.

LKT I6933 Irinotecan Hydrochloride Trihydrate 5 mg 61.1 Camptothecin analog; topoisomerase I inhibitor, potential AChE inhibitor. [1,4'-Bipiperidine]-1'-carboxylic acid (4S)-4,11- diethyl-3,4,12,14-tetrahydro-4-hydroxy-3,14-dioxo- 1H-pyrano[3',4':6,7]indolizino[1,2-b]quinolin-9-yl ester hydrochloride trihydrate Irinotecan hydrochloride trihydrate; Camptosar; Campto; CPT-11 136572-09-3 ≥98% 677.19 C33H38N4O6 HCl 3H2O CCC1=C2C=C(C=CC2=NC3=C1CN4C3=CC5=C(C4=O)COC(=O)C5(CC)O)OC(=O)N6CCC(CC6)N7CCCCC7.O.O.O.Cl Ambient 4°C Slightly soluble in water (25 mg/mL),  ethanol (7 mg/mL), chloroform. DMSO (100  mg/mL) "Hu J, Kinn J, Zirakzadeh AA, et al. The effects of chemotherapeutic drugs on human monocyte-derived dendritic cell differentiation and antigen presentation. Clin Exp Immunol. 2013 Jun;172(3):490-9. PMID: 23600838.

Pan P, Li Y, Yu H, et al. Molecular principle of topotecan resistance by topoisomerase I mutations through molecular modeling approaches. J Chem Inf Model. 2013 Apr 22;53(4):997-1006. PMID: 23521602.

Chen AY, Chen PM, Chen YJ. DNA topoisomerase I drugs and radiotherapy for lung cancer. J Thorac Dis. 2012 Aug;4(4):390-7. PMID: 22934142.

Chintala S, Tóth K, Cao S, et al. Se-methylselenocysteine sensitizes hypoxic tumor cells to irinotecan by targeting hypoxia-inducible factor 1alpha. Cancer Chemother Pharmacol. 2010 Oct;66(5):899-911. PMID: 20066420.

Dodds HM, Rivory LP. The mechanism for the inhibition of acetylcholinesterases by irinotecan (CPT-11). Mol Pharmacol. 1999 Dec;56(6):1346-53. PMID: 10570064.

" Not dangerous goods.

LKT I6933 Irinotecan Hydrochloride Trihydrate 10 mg 88.3 Camptothecin analog; topoisomerase I inhibitor, potential AChE inhibitor. [1,4'-Bipiperidine]-1'-carboxylic acid (4S)-4,11- diethyl-3,4,12,14-tetrahydro-4-hydroxy-3,14-dioxo- 1H-pyrano[3',4':6,7]indolizino[1,2-b]quinolin-9-yl ester hydrochloride trihydrate Irinotecan hydrochloride trihydrate; Camptosar; Campto; CPT-11 136572-09-3 ≥98% 677.19 C33H38N4O6 HCl 3H2O CCC1=C2C=C(C=CC2=NC3=C1CN4C3=CC5=C(C4=O)COC(=O)C5(CC)O)OC(=O)N6CCC(CC6)N7CCCCC7.O.O.O.Cl Ambient 4°C Slightly soluble in water (25 mg/mL),  ethanol (7 mg/mL), chloroform. DMSO (100  mg/mL) "Hu J, Kinn J, Zirakzadeh AA, et al. The effects of chemotherapeutic drugs on human monocyte-derived dendritic cell differentiation and antigen presentation. Clin Exp Immunol. 2013 Jun;172(3):490-9. PMID: 23600838.

Pan P, Li Y, Yu H, et al. Molecular principle of topotecan resistance by topoisomerase I mutations through molecular modeling approaches. J Chem Inf Model. 2013 Apr 22;53(4):997-1006. PMID: 23521602.

Chen AY, Chen PM, Chen YJ. DNA topoisomerase I drugs and radiotherapy for lung cancer. J Thorac Dis. 2012 Aug;4(4):390-7. PMID: 22934142.

Chintala S, Tóth K, Cao S, et al. Se-methylselenocysteine sensitizes hypoxic tumor cells to irinotecan by targeting hypoxia-inducible factor 1alpha. Cancer Chemother Pharmacol. 2010 Oct;66(5):899-911. PMID: 20066420.

Dodds HM, Rivory LP. The mechanism for the inhibition of acetylcholinesterases by irinotecan (CPT-11). Mol Pharmacol. 1999 Dec;56(6):1346-53. PMID: 10570064.

" Not dangerous goods.

LKT I6933 Irinotecan Hydrochloride Trihydrate 25 mg 136 Camptothecin analog; topoisomerase I inhibitor, potential AChE inhibitor. [1,4'-Bipiperidine]-1'-carboxylic acid (4S)-4,11- diethyl-3,4,12,14-tetrahydro-4-hydroxy-3,14-dioxo- 1H-pyrano[3',4':6,7]indolizino[1,2-b]quinolin-9-yl ester hydrochloride trihydrate Irinotecan hydrochloride trihydrate; Camptosar; Campto; CPT-11 136572-09-3 ≥98% 677.19 C33H38N4O6 HCl 3H2O CCC1=C2C=C(C=CC2=NC3=C1CN4C3=CC5=C(C4=O)COC(=O)C5(CC)O)OC(=O)N6CCC(CC6)N7CCCCC7.O.O.O.Cl Ambient 4°C Slightly soluble in water (25 mg/mL),  ethanol (7 mg/mL), chloroform. DMSO (100  mg/mL) "Hu J, Kinn J, Zirakzadeh AA, et al. The effects of chemotherapeutic drugs on human monocyte-derived dendritic cell differentiation and antigen presentation. Clin Exp Immunol. 2013 Jun;172(3):490-9. PMID: 23600838.

Pan P, Li Y, Yu H, et al. Molecular principle of topotecan resistance by topoisomerase I mutations through molecular modeling approaches. J Chem Inf Model. 2013 Apr 22;53(4):997-1006. PMID: 23521602.

Chen AY, Chen PM, Chen YJ. DNA topoisomerase I drugs and radiotherapy for lung cancer. J Thorac Dis. 2012 Aug;4(4):390-7. PMID: 22934142.

Chintala S, Tóth K, Cao S, et al. Se-methylselenocysteine sensitizes hypoxic tumor cells to irinotecan by targeting hypoxia-inducible factor 1alpha. Cancer Chemother Pharmacol. 2010 Oct;66(5):899-911. PMID: 20066420.

Dodds HM, Rivory LP. The mechanism for the inhibition of acetylcholinesterases by irinotecan (CPT-11). Mol Pharmacol. 1999 Dec;56(6):1346-53. PMID: 10570064.

" Not dangerous goods.

LKT I7074 Irsogladine Maleate 100 mg 92.5 NSAID; COX-1/2 and PDE inhibitor. 6-(2,5-Dichlorophenyl)-1,3,5-triazine-2,4-diamine maleate MN-1695; Gaslon 84504-69-8 ≥98% 372.17 C9H7Cl2N5 C4H4O4 C1=CC(=C(C=C1Cl)C2=NC(=NC(=N2)N)N)Cl.C(=CC(=O)O)C(=O)O Ambient Ambient Soluble in DMSO. "Kuramoto T, Umegaki E, Nouda S, et al. Preventive effect of irsogladine or omeprazole on non-steroidal anti-inflammatory drug-induced esophagitis, peptic ulcers, and small intestinal lesions in humans, a prospective randomized controlled study. BMC Gastroenterol. 2013 May 14;13:85. PMID: 23672202.

Akagi M, Amagase K, Murakami T, et al. Irsogladine: overview of the mechanisms of mucosal protective and healing- promoting actions in the gastrointestinal tract. Curr Pharm Des. 2013;19(1):106-14. PMID: 22950502.

Yamaguchi H, Suzuki K, Nagata M, et al. Irsogladine maleate ameliorates inflammation and fibrosis in mice with chronic colitis induced by dextran sulfate sodium. Med Mol Morphol. 2012 Jun;45(3):140-51. PMID: 23001296.

" Not dangerous goods.

LKT I7074 Irsogladine Maleate 500 mg 288.8 NSAID; COX-1/2 and PDE inhibitor. 6-(2,5-Dichlorophenyl)-1,3,5-triazine-2,4-diamine maleate MN-1695; Gaslon 84504-69-8 ≥98% 372.17 C9H7Cl2N5 C4H4O4 C1=CC(=C(C=C1Cl)C2=NC(=NC(=N2)N)N)Cl.C(=CC(=O)O)C(=O)O Ambient Ambient Soluble in DMSO. "Kuramoto T, Umegaki E, Nouda S, et al. Preventive effect of irsogladine or omeprazole on non-steroidal anti-inflammatory drug-induced esophagitis, peptic ulcers, and small intestinal lesions in humans, a prospective randomized controlled study. BMC Gastroenterol. 2013 May 14;13:85. PMID: 23672202.

Akagi M, Amagase K, Murakami T, et al. Irsogladine: overview of the mechanisms of mucosal protective and healing- promoting actions in the gastrointestinal tract. Curr Pharm Des. 2013;19(1):106-14. PMID: 22950502.

Yamaguchi H, Suzuki K, Nagata M, et al. Irsogladine maleate ameliorates inflammation and fibrosis in mice with chronic colitis induced by dextran sulfate sodium. Med Mol Morphol. 2012 Jun;45(3):140-51. PMID: 23001296.

" Not dangerous goods.

LKT I7074 Irsogladine Maleate 1 g 462.1 NSAID; COX-1/2 and PDE inhibitor. 6-(2,5-Dichlorophenyl)-1,3,5-triazine-2,4-diamine maleate MN-1695; Gaslon 84504-69-8 ≥98% 372.17 C9H7Cl2N5 C4H4O4 C1=CC(=C(C=C1Cl)C2=NC(=NC(=N2)N)N)Cl.C(=CC(=O)O)C(=O)O Ambient Ambient Soluble in DMSO. "Kuramoto T, Umegaki E, Nouda S, et al. Preventive effect of irsogladine or omeprazole on non-steroidal anti-inflammatory drug-induced esophagitis, peptic ulcers, and small intestinal lesions in humans, a prospective randomized controlled study. BMC Gastroenterol. 2013 May 14;13:85. PMID: 23672202.

Akagi M, Amagase K, Murakami T, et al. Irsogladine: overview of the mechanisms of mucosal protective and healing- promoting actions in the gastrointestinal tract. Curr Pharm Des. 2013;19(1):106-14. PMID: 22950502.

Yamaguchi H, Suzuki K, Nagata M, et al. Irsogladine maleate ameliorates inflammation and fibrosis in mice with chronic colitis induced by dextran sulfate sodium. Med Mol Morphol. 2012 Jun;45(3):140-51. PMID: 23001296.

" Not dangerous goods.

LKT I7259 Isoproterenol Hydrochloride 5 g 57.8 β-adrenergic agonist. (+/-)-Isoprenaline hydrochloride; 1-(3',4'-Dihydro- xyphenyl)-2-isopropylaminoethanol Hydrochloride; N-Isopropyl-DL-noradrenaline Hydrochloride 51-30-9 ≥98% 247.72 C11H17NO3 HCl CC(C)NCC(C1=CC(=C(C=C1)O)O)O.Cl Ambient Ambient Soluble in water (>300 mg/L), ethanol (20 mg/mL), and methanol. "Gong LL, Fang LH, Wang SB, et al. Coptisine exert cardioprotective effect through anti-oxidative and inhibition of RhoA/Rho kinase pathway on isoproterenol-induced myocardial infarction in rats. Atherosclerosis. 2012 May;222(1):50-8. PMID: 22387061.

Gump A, Haughney L, Fredberg J. Relaxation of activated airway smooth muscle: relative potency of isoproterenol vs. tidal stretch. J Appl Physiol (1985). 2001 Jun;90(6):2306-10. PMID: 11356796.

Green JF. Mechanism of action of isoproterenol on venous return. Am J Physiol. 1977 Feb;232(2):H152-6. PMID: 842647.

" Not dangerous goods.

LKT I7259 Isoproterenol Hydrochloride 25 g 173.3 β-adrenergic agonist. (+/-)-Isoprenaline hydrochloride; 1-(3',4'-Dihydro- xyphenyl)-2-isopropylaminoethanol Hydrochloride; N-Isopropyl-DL-noradrenaline Hydrochloride 51-30-9 ≥98% 247.72 C11H17NO3 HCl CC(C)NCC(C1=CC(=C(C=C1)O)O)O.Cl Ambient Ambient Soluble in water (>300 mg/L), ethanol (20 mg/mL), and methanol. "Gong LL, Fang LH, Wang SB, et al. Coptisine exert cardioprotective effect through anti-oxidative and inhibition of RhoA/Rho kinase pathway on isoproterenol-induced myocardial infarction in rats. Atherosclerosis. 2012 May;222(1):50-8. PMID: 22387061.

Gump A, Haughney L, Fredberg J. Relaxation of activated airway smooth muscle: relative potency of isoproterenol vs. tidal stretch. J Appl Physiol (1985). 2001 Jun;90(6):2306-10. PMID: 11356796.

Green JF. Mechanism of action of isoproterenol on venous return. Am J Physiol. 1977 Feb;232(2):H152-6. PMID: 842647.

" Not dangerous goods.

LKT I7259 Isoproterenol Hydrochloride 100 g 520 β-adrenergic agonist. (+/-)-Isoprenaline hydrochloride; 1-(3',4'-Dihydro- xyphenyl)-2-isopropylaminoethanol Hydrochloride; N-Isopropyl-DL-noradrenaline Hydrochloride 51-30-9 ≥98% 247.72 C11H17NO3 HCl CC(C)NCC(C1=CC(=C(C=C1)O)O)O.Cl Ambient Ambient Soluble in water (>300 mg/L), ethanol (20 mg/mL), and methanol. "Gong LL, Fang LH, Wang SB, et al. Coptisine exert cardioprotective effect through anti-oxidative and inhibition of RhoA/Rho kinase pathway on isoproterenol-induced myocardial infarction in rats. Atherosclerosis. 2012 May;222(1):50-8. PMID: 22387061.

Gump A, Haughney L, Fredberg J. Relaxation of activated airway smooth muscle: relative potency of isoproterenol vs. tidal stretch. J Appl Physiol (1985). 2001 Jun;90(6):2306-10. PMID: 11356796.

Green JF. Mechanism of action of isoproterenol on venous return. Am J Physiol. 1977 Feb;232(2):H152-6. PMID: 842647.

" Not dangerous goods.

LKT I7302 Isatin 100 g 40.7 Indole derivative found in Isatis, Calanthe, and Couroupita; MAO-B and guanylate cyclase inhibitor. Indole-2,3-dione 2,3-Indolinedione; 2,3-Diketoindoline 91-56-5 ≥97% 147.13 C8H5NO2 C1=CC=C2C(=C1)C(=O)C(=O)N2 Ambient Ambient Soluble in boiling alcohol, ether, boiling water and alkali hydroxide. "Liang C, Xia J, Lei D, et al. Synthesis, in vitro and in vivo antitumor activity of symmetrical bis-Schiff base derivatives of isatin. Eur J Med Chem. 2014 Mar 3;74:742-50. PMID: 24176732.

Socca EA, Luiz-Ferreira A, de Faria FM, et al. Inhibition of tumor necrosis factor-alpha and cyclooxigenase-2 by Isatin: a molecular mechanism of protection against TNBS-induced colitis in rats. Chem Biol Interact. 2014 Feb 25;209:48-55. PMID: 24316276.

Krishnegowda G, Prakasha Gowda AS, Tagaram HR, et al. Synthesis and biological evaluation of a novel class of isatin analogs as dual inhibitors of tubulin polymerization and Akt pathway. Bioorg Med Chem. 2011 Oct 15;19(20):6006-14. PMID: 21920762.

Chu W, Rothfuss J, d'Avignon A, et al. Isatin sulfonamide analogs containing a Michael addition acceptor: a new class of caspase 3/7 inhibitors. J Med Chem. 2007 Jul 26;50(15):3751-5. PMID: 17585855.

Malawska B. New anticonvulsant agents. Curr Top Med Chem. 2005;5(1):69-85. PMID: 15638779.

Edmondson DE, Mattevi A, Binda C, et al. Structure and mechanism of monoamine oxidase. Curr Med Chem. 2004 Aug;11(15):1983-93. PMID: 15279562.

Medvedev AE, Sandler M, Glover V. Interaction of isatin with type-A natriuretic peptide receptor: possible mechanism. Life Sci. 1998;62(26):2391-8. PMID: 9651105.

" Xi Not dangerous goods.

LKT I7302 Isatin 500 g 136 Indole derivative found in Isatis, Calanthe, and Couroupita; MAO-B and guanylate cyclase inhibitor. Indole-2,3-dione 2,3-Indolinedione; 2,3-Diketoindoline 91-56-5 ≥97% 147.13 C8H5NO2 C1=CC=C2C(=C1)C(=O)C(=O)N2 Ambient Ambient Soluble in boiling alcohol, ether, boiling water and alkali hydroxide. "Liang C, Xia J, Lei D, et al. Synthesis, in vitro and in vivo antitumor activity of symmetrical bis-Schiff base derivatives of isatin. Eur J Med Chem. 2014 Mar 3;74:742-50. PMID: 24176732.

Socca EA, Luiz-Ferreira A, de Faria FM, et al. Inhibition of tumor necrosis factor-alpha and cyclooxigenase-2 by Isatin: a molecular mechanism of protection against TNBS-induced colitis in rats. Chem Biol Interact. 2014 Feb 25;209:48-55. PMID: 24316276.

Krishnegowda G, Prakasha Gowda AS, Tagaram HR, et al. Synthesis and biological evaluation of a novel class of isatin analogs as dual inhibitors of tubulin polymerization and Akt pathway. Bioorg Med Chem. 2011 Oct 15;19(20):6006-14. PMID: 21920762.

Chu W, Rothfuss J, d'Avignon A, et al. Isatin sulfonamide analogs containing a Michael addition acceptor: a new class of caspase 3/7 inhibitors. J Med Chem. 2007 Jul 26;50(15):3751-5. PMID: 17585855.

Malawska B. New anticonvulsant agents. Curr Top Med Chem. 2005;5(1):69-85. PMID: 15638779.

Edmondson DE, Mattevi A, Binda C, et al. Structure and mechanism of monoamine oxidase. Curr Med Chem. 2004 Aug;11(15):1983-93. PMID: 15279562.

Medvedev AE, Sandler M, Glover V. Interaction of isatin with type-A natriuretic peptide receptor: possible mechanism. Life Sci. 1998;62(26):2391-8. PMID: 9651105.

" Xi Not dangerous goods.

LKT I7341 Isoniazid 5 g 19.3 Nicotinic acid derivative; InhA inhibitor. 4-Pyridinecarboxylic acid, hydrazide Isonicotinoylhydrazine; Rimitsid; Tubazid; Cotinazin; Dinacrin; Ditubin; Hycozid. 54-85-3 ≥98% 137.14 C6H7N3O C1=CN=CC=C1C(=O)NN In DMSO at +4 for 2 weeks at -80 for 6 months. Ambient Ambient Soluble in water (125 mg/mL, DMSO, methanol and ethanol (20 mg/mL). "Bernardes-Génisson V, Deraeve C, Chollet A, et al. Isoniazid: an update on the multiple mechanisms for a singular action. Curr Med Chem. 2013;20(35):4370-85. PMID: 23931278.

Argyrou A, Vetting MW, Blanchard JS. New insight into the mechanism of action of and resistance to isoniazid: interaction of Mycobacterium tuberculosis enoyl-ACP reductase with INH-NADP. J Am Chem Soc. 2007 Aug 8;129(31):9582-3. PMID: 17636923.

Oliveira JS, Vasconcelos IB, Moreira IS, et al. Enoyl reductases as targets for the development of anti-tubercular and anti-malarial agents. Curr Drug Targets. 2007 Mar;8(3):399-411. PMID: 17348833.

" Not dangerous goods.

LKT I7341 Isoniazid 50 g 23.4 Nicotinic acid derivative; InhA inhibitor. 4-Pyridinecarboxylic acid, hydrazide Isonicotinoylhydrazine; Rimitsid; Tubazid; Cotinazin; Dinacrin; Ditubin; Hycozid. 54-85-3 ≥98% 137.14 C6H7N3O C1=CN=CC=C1C(=O)NN In DMSO at +4 for 2 weeks at -80 for 6 months. Ambient Ambient Soluble in water (125 mg/mL, DMSO, methanol and ethanol (20 mg/mL). "Bernardes-Génisson V, Deraeve C, Chollet A, et al. Isoniazid: an update on the multiple mechanisms for a singular action. Curr Med Chem. 2013;20(35):4370-85. PMID: 23931278.

Argyrou A, Vetting MW, Blanchard JS. New insight into the mechanism of action of and resistance to isoniazid: interaction of Mycobacterium tuberculosis enoyl-ACP reductase with INH-NADP. J Am Chem Soc. 2007 Aug 8;129(31):9582-3. PMID: 17636923.

Oliveira JS, Vasconcelos IB, Moreira IS, et al. Enoyl reductases as targets for the development of anti-tubercular and anti-malarial agents. Curr Drug Targets. 2007 Mar;8(3):399-411. PMID: 17348833.

" Not dangerous goods.

LKT I7341 Isoniazid 100 g 35 Nicotinic acid derivative; InhA inhibitor. 4-Pyridinecarboxylic acid, hydrazide Isonicotinoylhydrazine; Rimitsid; Tubazid; Cotinazin; Dinacrin; Ditubin; Hycozid. 54-85-3 ≥98% 137.14 C6H7N3O C1=CN=CC=C1C(=O)NN In DMSO at +4 for 2 weeks at -80 for 6 months. Ambient Ambient Soluble in water (125 mg/mL, DMSO, methanol and ethanol (20 mg/mL). "Bernardes-Génisson V, Deraeve C, Chollet A, et al. Isoniazid: an update on the multiple mechanisms for a singular action. Curr Med Chem. 2013;20(35):4370-85. PMID: 23931278.

Argyrou A, Vetting MW, Blanchard JS. New insight into the mechanism of action of and resistance to isoniazid: interaction of Mycobacterium tuberculosis enoyl-ACP reductase with INH-NADP. J Am Chem Soc. 2007 Aug 8;129(31):9582-3. PMID: 17636923.

Oliveira JS, Vasconcelos IB, Moreira IS, et al. Enoyl reductases as targets for the development of anti-tubercular and anti-malarial agents. Curr Drug Targets. 2007 Mar;8(3):399-411. PMID: 17348833.

" Not dangerous goods.

LKT I7356 Isopropyl Thiogalactoside 1 g 60.9 Galactose analog, allolactose mimic, induces activation of lac operon. Isopropyl β-D-thiogalactoside; IPTG 367-93-1 ≥98% 238.3 C9H18O5S CC(C)SC1C(C(C(C(O1)CO)O)O)O Protect from light. Ambient -20°C Soluble in water. "Marbach A, Bettenbrock K. lac operon induction in Escherichia coli: Systematic comparison of IPTG and TMG induction and influence of the transacetylase LacA. J Biotechnol. 2012 Jan;157(1):82-8. PMID: 22079752.

Hansen LH, Knudsen S, Sørensen SJ. The effect of the lacY gene on the induction of IPTG inducible promoters, studied in Escherichia coli and Pseudomonas fluorescens. Curr Microbiol. 1998 Jun;36(6):341-7. PMID: 9608745.

" Xi, Carc. Not dangerous goods.

LKT I7356 Isopropyl Thiogalactoside 5 g 242.3 Galactose analog, allolactose mimic, induces activation of lac operon. Isopropyl β-D-thiogalactoside; IPTG 367-93-1 ≥98% 238.3 C9H18O5S CC(C)SC1C(C(C(C(O1)CO)O)O)O Protect from light. Ambient -20°C Soluble in water. "Marbach A, Bettenbrock K. lac operon induction in Escherichia coli: Systematic comparison of IPTG and TMG induction and influence of the transacetylase LacA. J Biotechnol. 2012 Jan;157(1):82-8. PMID: 22079752.

Hansen LH, Knudsen S, Sørensen SJ. The effect of the lacY gene on the induction of IPTG inducible promoters, studied in Escherichia coli and Pseudomonas fluorescens. Curr Microbiol. 1998 Jun;36(6):341-7. PMID: 9608745.

" Xi, Carc. Not dangerous goods.

LKT I7356 Isopropyl Thiogalactoside 10 g 419.5 Galactose analog, allolactose mimic, induces activation of lac operon. Isopropyl β-D-thiogalactoside; IPTG 367-93-1 ≥98% 238.3 C9H18O5S CC(C)SC1C(C(C(C(O1)CO)O)O)O Protect from light. Ambient -20°C Soluble in water. "Marbach A, Bettenbrock K. lac operon induction in Escherichia coli: Systematic comparison of IPTG and TMG induction and influence of the transacetylase LacA. J Biotechnol. 2012 Jan;157(1):82-8. PMID: 22079752.

Hansen LH, Knudsen S, Sørensen SJ. The effect of the lacY gene on the induction of IPTG inducible promoters, studied in Escherichia coli and Pseudomonas fluorescens. Curr Microbiol. 1998 Jun;36(6):341-7. PMID: 9608745.

" Xi, Carc. Not dangerous goods.

LKT I7357 Isorhamnetin 1 mg 61.1 Flavonol found in Tagetes. 3,5,7-Trihydroxy-2-(4-hydroxy-3-methoxyphenyl)-4-benzopyrone 3-Methylquercetin; Quercetin- 3'-methyl ether 480-19-3 ≥98% 316.26 C16H12O7 COC1=C(C=CC(=C1)C2=C(C(=O)C3=C(C=C(C=C3O2)O)O)O)O Ambient 4°C Soluble in acetone, methanol, ethylacetate, DMSO or water. "Seo K, Yang JH, Kim SC, et al. The antioxidant effects of isorhamnetin contribute to inhibit COX-2 expression in response to inflammation: a potential role of HO-1. Inflammation. 2014 Jun;37(3):712-22. PMID: 24337631.

Li C, Yang X, Chen C, et al. Isorhamnetin suppresses colon cancer cell growth through the PI3K Akt mTOR pathway. Mol Med Rep. 2014 Mar;9(3):935-40. PMID: 24398569.

Saud SM, Young MR, Jones-Hall YL, et al. Chemopreventive activity of plant flavonoid isorhamnetin in colorectal cancer is mediated by oncogenic Src and β-catenin. Cancer Res. 2013 Sep 1;73(17):5473-84. PMID: 23824743.

Kim JE, Lee DE, Lee KW, et al. Isorhamnetin suppresses skin cancer through direct inhibition of MEK1 and PI3-K. Cancer Prev Res (Phila). 2011 Apr;4(4):582-91. PMID: 21330379.

Lee J, Jung E, Lee J, et al. Isorhamnetin represses adipogenesis in 3T3-L1 cells. Obesity (Silver Spring). 2009 Feb;17(2):226-32. PMID: 18948972.

" Xn Not dangerous goods.

LKT I7357 Isorhamnetin 5 mg 136 Flavonol found in Tagetes. 3,5,7-Trihydroxy-2-(4-hydroxy-3-methoxyphenyl)-4-benzopyrone 3-Methylquercetin; Quercetin- 3'-methyl ether 480-19-3 ≥98% 316.26 C16H12O7 COC1=C(C=CC(=C1)C2=C(C(=O)C3=C(C=C(C=C3O2)O)O)O)O Ambient 4°C Soluble in acetone, methanol, ethylacetate, DMSO or water. "Seo K, Yang JH, Kim SC, et al. The antioxidant effects of isorhamnetin contribute to inhibit COX-2 expression in response to inflammation: a potential role of HO-1. Inflammation. 2014 Jun;37(3):712-22. PMID: 24337631.

Li C, Yang X, Chen C, et al. Isorhamnetin suppresses colon cancer cell growth through the PI3K Akt mTOR pathway. Mol Med Rep. 2014 Mar;9(3):935-40. PMID: 24398569.

Saud SM, Young MR, Jones-Hall YL, et al. Chemopreventive activity of plant flavonoid isorhamnetin in colorectal cancer is mediated by oncogenic Src and β-catenin. Cancer Res. 2013 Sep 1;73(17):5473-84. PMID: 23824743.

Kim JE, Lee DE, Lee KW, et al. Isorhamnetin suppresses skin cancer through direct inhibition of MEK1 and PI3-K. Cancer Prev Res (Phila). 2011 Apr;4(4):582-91. PMID: 21330379.

Lee J, Jung E, Lee J, et al. Isorhamnetin represses adipogenesis in 3T3-L1 cells. Obesity (Silver Spring). 2009 Feb;17(2):226-32. PMID: 18948972.

" Xn Not dangerous goods.

LKT I7359 1-Isothiocyanato-8-(methylsulfenyl)-octane 25 mg 130 ITC, erucin analog. 8-Methylsulfenyloctyl isothiocyanate ≥98% 217.4 C10H19NS2 Ambient -20°C Not dangerous goods.

LKT I7359 1-Isothiocyanato-8-(methylsulfenyl)-octane 50 mg 216.4 ITC, erucin analog. 8-Methylsulfenyloctyl isothiocyanate ≥98% 217.4 C10H19NS2 Ambient -20°C Not dangerous goods.

LKT I7359 1-Isothiocyanato-8-(methylsulfenyl)-octane 100 mg 360.5 ITC, erucin analog. 8-Methylsulfenyloctyl isothiocyanate ≥98% 217.4 C10H19NS2 Ambient -20°C Not dangerous goods.

LKT I7360 Isosorbide Mononitrate 5 g 104.3 NO donor. 1,4:3,6-Dianhydro-D-glucitol 5-mononitrate Isosorbide-5-mononitrate; Corangin; Elantan; Ismo; Monicor; Pentacard  16051-77-7 ≥98% 191.14 C6H9NO6 C1C(C2C(O1)C(CO2)O[N+](=O)[O-])O Ambient Ambient Soluble in water, ethanol, methanol, chloroform, ethyl acetate or dicloromethane. "Münzel T, Daiber A, Gori T. More answers to the still unresolved question of nitrate tolerance. Eur Heart J. 2013 Sep;34(34):2666-73. PMID: 23864131.

Cohn JN. Efficacy of vasodilators in the treatment of heart failure. J Am Coll Cardiol. 1993 Oct;22(4 Suppl A):135A-138A. PMID: 8376683.

Döring G. Antianginal and anti-ischemic efficacy of nicorandil in comparison with isosorbide-5-mononitrate and isosorbide dinitrate: results from two multicenter, double-blind, randomized studies with stable coronary heart disease patients. J Cardiovasc Pharmacol. 1992;20 Suppl 3:S74-81. PMID: 1282180.

" F, Xi Not dangerous goods.

LKT I7360 Isosorbide Mononitrate 10 g 173.3 NO donor. 1,4:3,6-Dianhydro-D-glucitol 5-mononitrate Isosorbide-5-mononitrate; Corangin; Elantan; Ismo; Monicor; Pentacard  16051-77-7 ≥98% 191.14 C6H9NO6 C1C(C2C(O1)C(CO2)O[N+](=O)[O-])O Ambient Ambient Soluble in water, ethanol, methanol, chloroform, ethyl acetate or dicloromethane. "Münzel T, Daiber A, Gori T. More answers to the still unresolved question of nitrate tolerance. Eur Heart J. 2013 Sep;34(34):2666-73. PMID: 23864131.

Cohn JN. Efficacy of vasodilators in the treatment of heart failure. J Am Coll Cardiol. 1993 Oct;22(4 Suppl A):135A-138A. PMID: 8376683.

Döring G. Antianginal and anti-ischemic efficacy of nicorandil in comparison with isosorbide-5-mononitrate and isosorbide dinitrate: results from two multicenter, double-blind, randomized studies with stable coronary heart disease patients. J Cardiovasc Pharmacol. 1992;20 Suppl 3:S74-81. PMID: 1282180.

" F, Xi Not dangerous goods.

LKT I7360 Isosorbide Mononitrate 25 g 346.5 NO donor. 1,4:3,6-Dianhydro-D-glucitol 5-mononitrate Isosorbide-5-mononitrate; Corangin; Elantan; Ismo; Monicor; Pentacard  16051-77-7 ≥98% 191.14 C6H9NO6 C1C(C2C(O1)C(CO2)O[N+](=O)[O-])O Ambient Ambient Soluble in water, ethanol, methanol, chloroform, ethyl acetate or dicloromethane. "Münzel T, Daiber A, Gori T. More answers to the still unresolved question of nitrate tolerance. Eur Heart J. 2013 Sep;34(34):2666-73. PMID: 23864131.

Cohn JN. Efficacy of vasodilators in the treatment of heart failure. J Am Coll Cardiol. 1993 Oct;22(4 Suppl A):135A-138A. PMID: 8376683.

Döring G. Antianginal and anti-ischemic efficacy of nicorandil in comparison with isosorbide-5-mononitrate and isosorbide dinitrate: results from two multicenter, double-blind, randomized studies with stable coronary heart disease patients. J Cardiovasc Pharmacol. 1992;20 Suppl 3:S74-81. PMID: 1282180.

" F, Xi Not dangerous goods.

LKT I7447 1-Isothiocyanato-6-(methylsulfenyl)-hexane 25 mg 130 Synthetic  ITC, erucin analog. 6-Methylsulfenylhexyl isothiocyanat ≥98% 189.34 C8H15NS2 Ambient -20°C Chen YJ, Huang YC, Tsai TH, et al. Effect of Wasabi Component 6-(Methylsulfinyl)hexyl Isothiocyanate and Derivatives on Human Pancreatic Cancer Cells. Evid Based Complement Alternat Med. 2014;2014:494739. PMID: 24575144. Not dangerous goods.

LKT I7447 1-Isothiocyanato-6-(methylsulfenyl)-hexane 50 mg 216.4 Synthetic  ITC, erucin analog. 6-Methylsulfenylhexyl isothiocyanat ≥98% 189.34 C8H15NS2 Ambient -20°C Chen YJ, Huang YC, Tsai TH, et al. Effect of Wasabi Component 6-(Methylsulfinyl)hexyl Isothiocyanate and Derivatives on Human Pancreatic Cancer Cells. Evid Based Complement Alternat Med. 2014;2014:494739. PMID: 24575144. Not dangerous goods.

LKT I7447 1-Isothiocyanato-6-(methylsulfenyl)-hexane 100 mg 360.5 Synthetic  ITC, erucin analog. 6-Methylsulfenylhexyl isothiocyanat ≥98% 189.34 C8H15NS2 Ambient -20°C Chen YJ, Huang YC, Tsai TH, et al. Effect of Wasabi Component 6-(Methylsulfinyl)hexyl Isothiocyanate and Derivatives on Human Pancreatic Cancer Cells. Evid Based Complement Alternat Med. 2014;2014:494739. PMID: 24575144. Not dangerous goods.

LKT I7456 1-Isothiocyanato-7-(methylsulfinyl)-heptane 10 mg 153 ITC, radical scavenger. 7-Methylsulfinylheptyl isothiocyanate 129244-98-0 ≥98% 219.37 C9H17NOS2 Ambient -20°C "Rose P, Huang Q, Ong CN, et al. Broccoli and watercress suppress matrix metalloproteinase-9 activity and invasiveness of human MDA-MB-231 breast cancer cells. Toxicol Appl Pharmacol. 2005 Dec 1;209(2):105-13. PMID: 15953625.

Kinae N, Masuda H, Shin IS, et al. Functional properties of wasabi and horseradish. Biofactors. 2000;13(1-4):265-9. PMID: 11237192.

Rose P, Faulkner K, Williamson G, et al. 7-Methylsulfinylheptyl and 8-methylsulfinyloctyl isothiocyanates from watercress are potent inducers of phase II enzymes. Carcinogenesis. 2000 Nov;21(11):1983-8. PMID: 11062158.

" Not dangerous goods.

LKT I7456 1-Isothiocyanato-7-(methylsulfinyl)-heptane 25 mg 360.5 ITC, radical scavenger. 7-Methylsulfinylheptyl isothiocyanate 129244-98-0 ≥98% 219.37 C9H17NOS2 Ambient -20°C "Rose P, Huang Q, Ong CN, et al. Broccoli and watercress suppress matrix metalloproteinase-9 activity and invasiveness of human MDA-MB-231 breast cancer cells. Toxicol Appl Pharmacol. 2005 Dec 1;209(2):105-13. PMID: 15953625.

Kinae N, Masuda H, Shin IS, et al. Functional properties of wasabi and horseradish. Biofactors. 2000;13(1-4):265-9. PMID: 11237192.

Rose P, Faulkner K, Williamson G, et al. 7-Methylsulfinylheptyl and 8-methylsulfinyloctyl isothiocyanates from watercress are potent inducers of phase II enzymes. Carcinogenesis. 2000 Nov;21(11):1983-8. PMID: 11062158.

" Not dangerous goods.

LKT I7456 1-Isothiocyanato-7-(methylsulfinyl)-heptane 50 mg 576.6 ITC, radical scavenger. 7-Methylsulfinylheptyl isothiocyanate 129244-98-0 ≥98% 219.37 C9H17NOS2 Ambient -20°C "Rose P, Huang Q, Ong CN, et al. Broccoli and watercress suppress matrix metalloproteinase-9 activity and invasiveness of human MDA-MB-231 breast cancer cells. Toxicol Appl Pharmacol. 2005 Dec 1;209(2):105-13. PMID: 15953625.

Kinae N, Masuda H, Shin IS, et al. Functional properties of wasabi and horseradish. Biofactors. 2000;13(1-4):265-9. PMID: 11237192.

Rose P, Faulkner K, Williamson G, et al. 7-Methylsulfinylheptyl and 8-methylsulfinyloctyl isothiocyanates from watercress are potent inducers of phase II enzymes. Carcinogenesis. 2000 Nov;21(11):1983-8. PMID: 11062158.

" Not dangerous goods.

LKT I7456 1-Isothiocyanato-7-(methylsulfinyl)-heptane 100 mg 1008.9 ITC, radical scavenger. 7-Methylsulfinylheptyl isothiocyanate 129244-98-0 ≥98% 219.37 C9H17NOS2 Ambient -20°C "Rose P, Huang Q, Ong CN, et al. Broccoli and watercress suppress matrix metalloproteinase-9 activity and invasiveness of human MDA-MB-231 breast cancer cells. Toxicol Appl Pharmacol. 2005 Dec 1;209(2):105-13. PMID: 15953625.

Kinae N, Masuda H, Shin IS, et al. Functional properties of wasabi and horseradish. Biofactors. 2000;13(1-4):265-9. PMID: 11237192.

Rose P, Faulkner K, Williamson G, et al. 7-Methylsulfinylheptyl and 8-methylsulfinyloctyl isothiocyanates from watercress are potent inducers of phase II enzymes. Carcinogenesis. 2000 Nov;21(11):1983-8. PMID: 11062158.

" Not dangerous goods.

LKT I7457 1-Isothiocyanato-6-(methylsulfinyl)-hexane 25 mg 182.5 Synthetic derivative of 6-methylsulfinyl-hexane ITC, analog of sulforaphane; GSK-3β inhibitor. 6-Methylsulfinylhexyl isothiocyanate ≥98% 205.34 C8H15NOS2 Ambient -20°C "Fuke Y, Hishinuma M, Namikawa M, et al. Wasabi-derived 6-(methylsulfinyl)hexyl isothiocyanate induces apoptosis in human breast cancer by possible involvement of the NF-κB pathways. Nutr Cancer. 2014;66(5):879-87. PMID: 24895898.

Chen YJ, Huang YC, Tsai TH, et al. Effect of Wasabi Component 6-(Methylsulfinyl)hexyl Isothiocyanate and Derivatives on Human Pancreatic Cancer Cells. Evid Based Complement Alternat Med. 2014;2014:494739. PMID: 24575144.

Uto T, Hou DX, Morinaga O, et al. Molecular Mechanisms Underlying Anti-Inflammatory Actions of 6-(Methylsulfinyl)hexyl Isothiocyanate Derived from Wasabi (Wasabia japonica). Adv Pharmacol Sci. 2012;2012:614046. PMID: 22927840.

Mizuno K, Kume T, Muto C, et al. Glutathione biosynthesis via activation of the nuclear factor E2-related factor 2 (Nrf2)--antioxidant-response element (ARE) pathway is essential for neuroprotective effects of sulforaphane and 6-(methylsulfinyl) hexyl isothiocyanate. J Pharmacol Sci. 2011;115(3):320-8. PMID: 21358121.

Yoshida J, Nomura S, Nishizawa N, et al. Glycogen synthase kinase-3β inhibition of 6-(methylsulfinyl)hexyl isothiocyanate derived from wasabi (Wasabia japonica Matsum). Biosci Biotechnol Biochem. 2011;75(1):136-9. PMID: 21228474.

" Not dangerous goods.

LKT I7457 1-Isothiocyanato-6-(methylsulfinyl)-hexane 50 mg 303.3 Synthetic derivative of 6-methylsulfinyl-hexane ITC, analog of sulforaphane; GSK-3β inhibitor. 6-Methylsulfinylhexyl isothiocyanate ≥98% 205.34 C8H15NOS2 Ambient -20°C "Fuke Y, Hishinuma M, Namikawa M, et al. Wasabi-derived 6-(methylsulfinyl)hexyl isothiocyanate induces apoptosis in human breast cancer by possible involvement of the NF-κB pathways. Nutr Cancer. 2014;66(5):879-87. PMID: 24895898.

Chen YJ, Huang YC, Tsai TH, et al. Effect of Wasabi Component 6-(Methylsulfinyl)hexyl Isothiocyanate and Derivatives on Human Pancreatic Cancer Cells. Evid Based Complement Alternat Med. 2014;2014:494739. PMID: 24575144.

Uto T, Hou DX, Morinaga O, et al. Molecular Mechanisms Underlying Anti-Inflammatory Actions of 6-(Methylsulfinyl)hexyl Isothiocyanate Derived from Wasabi (Wasabia japonica). Adv Pharmacol Sci. 2012;2012:614046. PMID: 22927840.

Mizuno K, Kume T, Muto C, et al. Glutathione biosynthesis via activation of the nuclear factor E2-related factor 2 (Nrf2)--antioxidant-response element (ARE) pathway is essential for neuroprotective effects of sulforaphane and 6-(methylsulfinyl) hexyl isothiocyanate. J Pharmacol Sci. 2011;115(3):320-8. PMID: 21358121.

Yoshida J, Nomura S, Nishizawa N, et al. Glycogen synthase kinase-3β inhibition of 6-(methylsulfinyl)hexyl isothiocyanate derived from wasabi (Wasabia japonica Matsum). Biosci Biotechnol Biochem. 2011;75(1):136-9. PMID: 21228474.

" Not dangerous goods.

LKT I7457 1-Isothiocyanato-6-(methylsulfinyl)-hexane 100 mg 545.9 Synthetic derivative of 6-methylsulfinyl-hexane ITC, analog of sulforaphane; GSK-3β inhibitor. 6-Methylsulfinylhexyl isothiocyanate ≥98% 205.34 C8H15NOS2 Ambient -20°C "Fuke Y, Hishinuma M, Namikawa M, et al. Wasabi-derived 6-(methylsulfinyl)hexyl isothiocyanate induces apoptosis in human breast cancer by possible involvement of the NF-κB pathways. Nutr Cancer. 2014;66(5):879-87. PMID: 24895898.

Chen YJ, Huang YC, Tsai TH, et al. Effect of Wasabi Component 6-(Methylsulfinyl)hexyl Isothiocyanate and Derivatives on Human Pancreatic Cancer Cells. Evid Based Complement Alternat Med. 2014;2014:494739. PMID: 24575144.

Uto T, Hou DX, Morinaga O, et al. Molecular Mechanisms Underlying Anti-Inflammatory Actions of 6-(Methylsulfinyl)hexyl Isothiocyanate Derived from Wasabi (Wasabia japonica). Adv Pharmacol Sci. 2012;2012:614046. PMID: 22927840.

Mizuno K, Kume T, Muto C, et al. Glutathione biosynthesis via activation of the nuclear factor E2-related factor 2 (Nrf2)--antioxidant-response element (ARE) pathway is essential for neuroprotective effects of sulforaphane and 6-(methylsulfinyl) hexyl isothiocyanate. J Pharmacol Sci. 2011;115(3):320-8. PMID: 21358121.

Yoshida J, Nomura S, Nishizawa N, et al. Glycogen synthase kinase-3β inhibition of 6-(methylsulfinyl)hexyl isothiocyanate derived from wasabi (Wasabia japonica Matsum). Biosci Biotechnol Biochem. 2011;75(1):136-9. PMID: 21228474.

" Not dangerous goods.

LKT I7458 1-Isothiocyanato-9-(methylsulfinyl)-nonane 25 mg 182.5 ITC, sulforaphane analog. 9-Methylsulfinylnonnyl isothiocyanate ≥98% 247.42 C11H21NOS2 Ambient -20°C Not dangerous goods.

LKT I7458 1-Isothiocyanato-9-(methylsulfinyl)-nonane 50 mg 303.3 ITC, sulforaphane analog. 9-Methylsulfinylnonnyl isothiocyanate ≥98% 247.42 C11H21NOS2 Ambient -20°C Not dangerous goods.

LKT I7458 1-Isothiocyanato-9-(methylsulfinyl)-nonane 100 mg 545.9 ITC, sulforaphane analog. 9-Methylsulfinylnonnyl isothiocyanate ≥98% 247.42 C11H21NOS2 Ambient -20°C Not dangerous goods.

LKT I7556 1-Isothiocyanato-7-(methylsulfonyl)-heptane 10 mg 101.1 ITC, erysolin analog. 7-Methylsulfonylheptyl isothiocyanate ≥98% 235.37 C9H17NO2S2 Ambient -20°C Not dangerous goods.

LKT I7556 1-Isothiocyanato-7-(methylsulfonyl)-heptane 25 mg 216.4 ITC, erysolin analog. 7-Methylsulfonylheptyl isothiocyanate ≥98% 235.37 C9H17NO2S2 Ambient -20°C Not dangerous goods.

LKT I7556 1-Isothiocyanato-7-(methylsulfonyl)-heptane 50 mg 369 ITC, erysolin analog. 7-Methylsulfonylheptyl isothiocyanate ≥98% 235.37 C9H17NO2S2 Ambient -20°C Not dangerous goods.

LKT I7557 1-Isothiocyanato-6-(methylsulfonyl)-hexane 100 mg 513.1 Synthetic  ITC, erysolin analog. 6-Methylsulfonylhexyl isothiocyanate ≥98% 221.34 C8H15NO2S2 Ambient -20°C Chen YJ, Huang YC, Tsai TH, et al. Effect of Wasabi Component 6-(Methylsulfinyl)hexyl Isothiocyanate and Derivatives on Human Pancreatic Cancer Cells. Evid Based Complement Alternat Med. 2014;2014:494739. PMID: 24575144. Not dangerous goods.

LKT I7557 1-Isothiocyanato-6-(methylsulfonyl)-hexane 50 mg 300 Synthetic  ITC, erysolin analog. 6-Methylsulfonylhexyl isothiocyanate ≥98% 221.34 C8H15NO2S2 Ambient -20°C Chen YJ, Huang YC, Tsai TH, et al. Effect of Wasabi Component 6-(Methylsulfinyl)hexyl Isothiocyanate and Derivatives on Human Pancreatic Cancer Cells. Evid Based Complement Alternat Med. 2014;2014:494739. PMID: 24575144. Not dangerous goods.

LKT I7557 1-Isothiocyanato-6-(methylsulfonyl)-hexane 25 mg 167.3 Synthetic  ITC, erysolin analog. 6-Methylsulfonylhexyl isothiocyanate ≥98% 221.34 C8H15NO2S2 Ambient -20°C Chen YJ, Huang YC, Tsai TH, et al. Effect of Wasabi Component 6-(Methylsulfinyl)hexyl Isothiocyanate and Derivatives on Human Pancreatic Cancer Cells. Evid Based Complement Alternat Med. 2014;2014:494739. PMID: 24575144. Not dangerous goods.

LKT I7558 1-Isothiocyanato-9-(methylsulfenyl)-nonane 25 mg 130 ITC, erucin analog. 9-Methylsulfenylnonyl isothiocyanate ≥97% 234.42 C11H21NS2 Ambient -20°C Not dangerous goods.

LKT I7558 1-Isothiocyanato-9-(methylsulfenyl)-nonane 50 mg 216.4 ITC, erucin analog. 9-Methylsulfenylnonyl isothiocyanate ≥97% 234.42 C11H21NS2 Ambient -20°C Not dangerous goods.

LKT I7558 1-Isothiocyanato-9-(methylsulfenyl)-nonane 100 mg 360.5 ITC, erucin analog. 9-Methylsulfenylnonyl isothiocyanate ≥97% 234.42 C11H21NS2 Ambient -20°C Not dangerous goods.

LKT I7658 1-Isothiocyanato-9-(methylsulfonyl)-nonane 25 mg 167.3 Synthetic ITC, erysolin analog. 9-Methylsulfonylnonyl isothiocyanate ≥98% 263.42 C11H21NO2S2 Ambient -20°C Not dangerous goods.

LKT I7658 1-Isothiocyanato-9-(methylsulfonyl)-nonane 50 mg 300 Synthetic ITC, erysolin analog. 9-Methylsulfonylnonyl isothiocyanate ≥98% 263.42 C11H21NO2S2 Ambient -20°C Not dangerous goods.

LKT I7658 1-Isothiocyanato-9-(methylsulfonyl)-nonane 100 mg 513.1 Synthetic ITC, erysolin analog. 9-Methylsulfonylnonyl isothiocyanate ≥98% 263.42 C11H21NO2S2 Ambient -20°C Not dangerous goods.

LKT I7659 1-Isothiocyanato-8-(methylsulfonyl)-octane 25 mg 167.3 ITC, erysolin analog. 8-Methylsulfonyloctyl isothiocyanate ≥98% 249.4 C10H19NO2S2 Ambient -20°C Not dangerous goods.

LKT I7659 1-Isothiocyanato-8-(methylsulfonyl)-octane 50 mg 300 ITC, erysolin analog. 8-Methylsulfonyloctyl isothiocyanate ≥98% 249.4 C10H19NO2S2 Ambient -20°C Not dangerous goods.

LKT I7659 1-Isothiocyanato-8-(methylsulfonyl)-octane 100 mg 513.1 ITC, erysolin analog. 8-Methylsulfonyloctyl isothiocyanate ≥98% 249.4 C10H19NO2S2 Ambient -20°C Not dangerous goods.

LKT I7746 1-Isothiocyanato-7-(methylsulfenyl)-heptane 10 mg 101.1 ITC, erucin analog. 7-Methylsulfenylheptyl isothiocyanate ≥98% 203.37 C9H17NS2 Ambient -20°C Not dangerous goods.

LKT I7746 1-Isothiocyanato-7-(methylsulfenyl)-heptane 25 mg 216.4 ITC, erucin analog. 7-Methylsulfenylheptyl isothiocyanate ≥98% 203.37 C9H17NS2 Ambient -20°C Not dangerous goods.

LKT I7746 1-Isothiocyanato-7-(methylsulfenyl)-heptane 50 mg 369 ITC, erucin analog. 7-Methylsulfenylheptyl isothiocyanate ≥98% 203.37 C9H17NS2 Ambient -20°C Not dangerous goods.

LKT I7757 Itopride Hydrochloride 1 g 104.3 AChE inhibitor, D2 antagonist. N-[[4-(2-dimethylaminoethoxy)phenyl]methyl]-3,4- dimethoxy-benzamide 122892-31-3 ≥98% 394.88 C20H26N2O4 HCl CN(C)CCOC1=CC=C(C=C1)CNC(=O)C2=CC(=C(C=C2)OC)OC.Cl Ambient Ambient Soluble in water or methanol. Sparingly soluble in acetic acid. "Huang X, Lv B, Zhang S, et al. Itopride therapy for functional dyspepsia: a meta-analysis. World J Gastroenterol. 2012 Dec 28;18(48):7371-7. PMID: 23326147.

Scarpellini E, Vos R, Blondeau K, et al. The effects of itopride on oesophageal motility and lower oesophageal sphincter function in man. Aliment Pharmacol Ther. 2011 Jan;33(1):99-105. PMID: 21083582.

Lim HC, Kim YG, Lim JH, et al. Effect of itopride hydrochloride on the ileal and colonic motility in guinea pig in vitro. Yonsei Med J. 2008 Jun 30;49(3):472-8. PMID: 18581598.

Fujitsuka N, Asakawa A, Hayashi M, et al. Selective serotonin reuptake inhibitors modify physiological gastrointestinal motor activities via 5-HT2c receptor and acyl ghrelin. Biol Psychiatry. 2009 May 1;65(9):748-759. PMID: 19058784.

" Not dangerous goods.

LKT I7757 Itopride Hydrochloride 5 g 427.6 AChE inhibitor, D2 antagonist. N-[[4-(2-dimethylaminoethoxy)phenyl]methyl]-3,4- dimethoxy-benzamide 122892-31-3 ≥98% 394.88 C20H26N2O4 HCl CN(C)CCOC1=CC=C(C=C1)CNC(=O)C2=CC(=C(C=C2)OC)OC.Cl Ambient Ambient Soluble in water or methanol. Sparingly soluble in acetic acid. "Huang X, Lv B, Zhang S, et al. Itopride therapy for functional dyspepsia: a meta-analysis. World J Gastroenterol. 2012 Dec 28;18(48):7371-7. PMID: 23326147.

Scarpellini E, Vos R, Blondeau K, et al. The effects of itopride on oesophageal motility and lower oesophageal sphincter function in man. Aliment Pharmacol Ther. 2011 Jan;33(1):99-105. PMID: 21083582.

Lim HC, Kim YG, Lim JH, et al. Effect of itopride hydrochloride on the ileal and colonic motility in guinea pig in vitro. Yonsei Med J. 2008 Jun 30;49(3):472-8. PMID: 18581598.

Fujitsuka N, Asakawa A, Hayashi M, et al. Selective serotonin reuptake inhibitors modify physiological gastrointestinal motor activities via 5-HT2c receptor and acyl ghrelin. Biol Psychiatry. 2009 May 1;65(9):748-759. PMID: 19058784.

" Not dangerous goods.

LKT I7757 Itopride Hydrochloride 25 g 1291 AChE inhibitor, D2 antagonist. N-[[4-(2-dimethylaminoethoxy)phenyl]methyl]-3,4- dimethoxy-benzamide 122892-31-3 ≥98% 394.88 C20H26N2O4 HCl CN(C)CCOC1=CC=C(C=C1)CNC(=O)C2=CC(=C(C=C2)OC)OC.Cl Ambient Ambient Soluble in water or methanol. Sparingly soluble in acetic acid. "Huang X, Lv B, Zhang S, et al. Itopride therapy for functional dyspepsia: a meta-analysis. World J Gastroenterol. 2012 Dec 28;18(48):7371-7. PMID: 23326147.

Scarpellini E, Vos R, Blondeau K, et al. The effects of itopride on oesophageal motility and lower oesophageal sphincter function in man. Aliment Pharmacol Ther. 2011 Jan;33(1):99-105. PMID: 21083582.

Lim HC, Kim YG, Lim JH, et al. Effect of itopride hydrochloride on the ileal and colonic motility in guinea pig in vitro. Yonsei Med J. 2008 Jun 30;49(3):472-8. PMID: 18581598.

Fujitsuka N, Asakawa A, Hayashi M, et al. Selective serotonin reuptake inhibitors modify physiological gastrointestinal motor activities via 5-HT2c receptor and acyl ghrelin. Biol Psychiatry. 2009 May 1;65(9):748-759. PMID: 19058784.

" Not dangerous goods.

LKT I7870 Itraconazole 50 mg 55 Triazole; 14-α demethylase inhibitor, Smo modulator. 4-[4-[4-[4-[[2-(2,4-Dichlorophenyl)-2-(1H-1,2,4- triazol-1-ylmethyl)-1,3-dioxolan-4-yl]methoxy]- phenyl]-1-peperazinyl]phenyl]-2,4-dihydro-2-(1- methylpropyl)-3H-1,2,4-triazol-3one Oriconazole; Itrizole; Sporanox; Triasporin 84625-61-6 ≥98% 705.63 C35H38Cl2N8O4 CCC(C)N1C(=O)N(C=N1)C2=CC=C(C=C2)N3CCN(CC3)C4=CC=C(C=C4)OCC5COC(O5)(CN6C=NC=N6)C7=C(C=C(C=C7)Cl)Cl Ambient Ambient Soluble in chloroform (50mg/mL). Practically insoluble in water and dilute acidic solutions. DMSO:4mg/mL "Kim J, Tang JY, Gong R, et al. Itraconazole, a commonly used antifungal that inhibits Hedgehog pathway activity and cancer growth. Cancer Cell. 2010 Apr 13;17(4):388-99. PMID: 20385363.

Chong CR, Xu J, Lu J, et al. Inhibition of angiogenesis by the antifungal drug itraconazole. ACS Chem Biol. 2007 Apr 24;2(4):263-70. PMID: 17432820.

" Xi Not dangerous goods.

LKT I7870 Itraconazole 100 mg 96.2 Triazole; 14-α demethylase inhibitor, Smo modulator. 4-[4-[4-[4-[[2-(2,4-Dichlorophenyl)-2-(1H-1,2,4- triazol-1-ylmethyl)-1,3-dioxolan-4-yl]methoxy]- phenyl]-1-peperazinyl]phenyl]-2,4-dihydro-2-(1- methylpropyl)-3H-1,2,4-triazol-3one Oriconazole; Itrizole; Sporanox; Triasporin 84625-61-6 ≥98% 705.63 C35H38Cl2N8O4 CCC(C)N1C(=O)N(C=N1)C2=CC=C(C=C2)N3CCN(CC3)C4=CC=C(C=C4)OCC5COC(O5)(CN6C=NC=N6)C7=C(C=C(C=C7)Cl)Cl Ambient Ambient Soluble in chloroform (50mg/mL). Practically insoluble in water and dilute acidic solutions. DMSO:4mg/mL "Kim J, Tang JY, Gong R, et al. Itraconazole, a commonly used antifungal that inhibits Hedgehog pathway activity and cancer growth. Cancer Cell. 2010 Apr 13;17(4):388-99. PMID: 20385363.

Chong CR, Xu J, Lu J, et al. Inhibition of angiogenesis by the antifungal drug itraconazole. ACS Chem Biol. 2007 Apr 24;2(4):263-70. PMID: 17432820.

" Xi Not dangerous goods.

LKT I7870 Itraconazole 250 mg 192.4 Triazole; 14-α demethylase inhibitor, Smo modulator. 4-[4-[4-[4-[[2-(2,4-Dichlorophenyl)-2-(1H-1,2,4- triazol-1-ylmethyl)-1,3-dioxolan-4-yl]methoxy]- phenyl]-1-peperazinyl]phenyl]-2,4-dihydro-2-(1- methylpropyl)-3H-1,2,4-triazol-3one Oriconazole; Itrizole; Sporanox; Triasporin 84625-61-6 ≥98% 705.63 C35H38Cl2N8O4 CCC(C)N1C(=O)N(C=N1)C2=CC=C(C=C2)N3CCN(CC3)C4=CC=C(C=C4)OCC5COC(O5)(CN6C=NC=N6)C7=C(C=C(C=C7)Cl)Cl Ambient Ambient Soluble in chloroform (50mg/mL). Practically insoluble in water and dilute acidic solutions. DMSO:4mg/mL "Kim J, Tang JY, Gong R, et al. Itraconazole, a commonly used antifungal that inhibits Hedgehog pathway activity and cancer growth. Cancer Cell. 2010 Apr 13;17(4):388-99. PMID: 20385363.

Chong CR, Xu J, Lu J, et al. Inhibition of angiogenesis by the antifungal drug itraconazole. ACS Chem Biol. 2007 Apr 24;2(4):263-70. PMID: 17432820.

" Xi Not dangerous goods.

LKT I7870 Itraconazole 1 g 570.3 Triazole; 14-α demethylase inhibitor, Smo modulator. 4-[4-[4-[4-[[2-(2,4-Dichlorophenyl)-2-(1H-1,2,4- triazol-1-ylmethyl)-1,3-dioxolan-4-yl]methoxy]- phenyl]-1-peperazinyl]phenyl]-2,4-dihydro-2-(1- methylpropyl)-3H-1,2,4-triazol-3one Oriconazole; Itrizole; Sporanox; Triasporin 84625-61-6 ≥98% 705.63 C35H38Cl2N8O4 CCC(C)N1C(=O)N(C=N1)C2=CC=C(C=C2)N3CCN(CC3)C4=CC=C(C=C4)OCC5COC(O5)(CN6C=NC=N6)C7=C(C=C(C=C7)Cl)Cl Ambient Ambient Soluble in chloroform (50mg/mL). Practically insoluble in water and dilute acidic solutions. DMSO:4mg/mL "Kim J, Tang JY, Gong R, et al. Itraconazole, a commonly used antifungal that inhibits Hedgehog pathway activity and cancer growth. Cancer Cell. 2010 Apr 13;17(4):388-99. PMID: 20385363.

Chong CR, Xu J, Lu J, et al. Inhibition of angiogenesis by the antifungal drug itraconazole. ACS Chem Biol. 2007 Apr 24;2(4):263-70. PMID: 17432820.

" Xi Not dangerous goods.

LKT I8618 Ivermectin 1 g 69.3 Avermectin; glu-gated Cl- channel activator, GlyR and GABA-A agonist. 22,23-Dihydroabamectin 22,23-Dihydroavermectin B1; MK-933; Heartgard 30; Mectizan; Stromectol; Zimecterin  70288-86-7 ≥95% 875.09 C48H74O14 CCC(C)C1C(CCC2(O1)CC3CC(O2)CC=C(C(C(C=CC=C4COC5C4(C(C=C(C5O)C)C(=O)O3)O)C)OC6CC(C(C(O6)C)OC7CC(C(C(O7)C)O)OC)OC)C)C Ambient 4°C Soluble in methyl ethyl ketone, propylene glycol, and polyethylene glycol. Insoluble in water. "Chaccour CJ, Kobylinski KC, Bassat Q, et al. Ivermectin to reduce malaria transmission: a research agenda for a promising new tool for elimination. Malar J. 2013 May 7;12:153. PMID: 23647969.

Lynagh T, Lynch JW. Molecular mechanisms of Cys-loop ion channel receptor modulation by ivermectin. Front Mol Neurosci. 2012 May 7;5:60. PMID: 22586367.

Yates DM, Wolstenholme AJ. An ivermectin-sensitive glutamate-gated chloride channel subunit from Dirofilaria immitis. Int J Parasitol. 2004 Aug;34(9):1075-81. PMID: 15313134.

" T+ "UN number: 2811     Class:  6.1     Packing group:  II

Proper shipping name:  Toxic solids, organic, n.o.s. (Ivermectin)

Reportable Quantity (RQ):"

LKT I8618 Ivermectin 5 g 288.8 Avermectin; glu-gated Cl- channel activator, GlyR and GABA-A agonist. 22,23-Dihydroabamectin 22,23-Dihydroavermectin B1; MK-933; Heartgard 30; Mectizan; Stromectol; Zimecterin  70288-86-7 ≥95% 875.09 C48H74O14 CCC(C)C1C(CCC2(O1)CC3CC(O2)CC=C(C(C(C=CC=C4COC5C4(C(C=C(C5O)C)C(=O)O3)O)C)OC6CC(C(C(O6)C)OC7CC(C(C(O7)C)O)OC)OC)C)C Ambient 4°C Soluble in methyl ethyl ketone, propylene glycol, and polyethylene glycol. Insoluble in water. "Chaccour CJ, Kobylinski KC, Bassat Q, et al. Ivermectin to reduce malaria transmission: a research agenda for a promising new tool for elimination. Malar J. 2013 May 7;12:153. PMID: 23647969.

Lynagh T, Lynch JW. Molecular mechanisms of Cys-loop ion channel receptor modulation by ivermectin. Front Mol Neurosci. 2012 May 7;5:60. PMID: 22586367.

Yates DM, Wolstenholme AJ. An ivermectin-sensitive glutamate-gated chloride channel subunit from Dirofilaria immitis. Int J Parasitol. 2004 Aug;34(9):1075-81. PMID: 15313134.

" T+ "UN number: 2811     Class:  6.1     Packing group:  II

Proper shipping name:  Toxic solids, organic, n.o.s. (Ivermectin)

Reportable Quantity (RQ):"

LKT L0060 Lappaconitine 25 mg 127.1 Alkaloid originally found in species of Aconitum; cardiac Na+ channel blocker. (1α,14α,16β)-20-Ethyl-1,14,16-trimethoxyaconitane- 4,8,9-triol 4-[2-(acetylamino)-benzoate] (+)-Lappaconitine 32854-75-4 ≥98% 584.7 C32H44N2O8 CCN1CC2(CCC(C34C2CC(C31)C5(CC(C6CC4C5(C6OC)O)OC)O)OC)OC(=O)C7=CC=CC=C7NC(=O)C Ambient 4°C Soluble in benzene. Slightly soluble in alcohol and ether. Practically insoluble in water. "Ou S, Zhao YD, Xiao Z, et al. Effect of lappaconitine on neuropathic pain mediated by P2X3 receptor in rat dorsal root ganglion. Neurochem Int. 2011 Apr;58(5):564-73. PMID: 21272608.

Wang YZ, Xiao YQ, Zhang C, et al. Study of analgesic and anti-inflammatory effects of lappaconitine gelata. J Tradit Chin Med. 2009 Jun;29(2):141-5. PMID: 19663103.

Wright SN. Irreversible block of human heart (hH1) sodium channels by the plant alkaloid lappaconitine. Mol Pharmacol. 2001 Feb;59(2):183-92. PMID: 11160852.

Heubach JF, Schüle A. Cardiac effects of lappaconitine and N-deacetyllappaconitine, two diterpenoid alkaloids from plants of the Aconitum and Delphinium species. Planta Med. 1998 Feb;64(1):22-6. PMID: 9491764.

Ameri A, Gleitz J, Peters T. Bicuculline-induced epileptiform activity in rat hippocampal slices: suppression by Aconitum alkaloids. Planta Med. 1997 Jun;63(3):228-32. PMID: 9225604.

" "UN number: 1544     Class: 6.1     Packing Group: II

Proper shipping name: Alkaloids, solid, n.o.s. (Lappaconitine)"

LKT L0060 Lappaconitine 100 mg 381.3 Alkaloid originally found in species of Aconitum; cardiac Na+ channel blocker. (1α,14α,16β)-20-Ethyl-1,14,16-trimethoxyaconitane- 4,8,9-triol 4-[2-(acetylamino)-benzoate] (+)-Lappaconitine 32854-75-4 ≥98% 584.7 C32H44N2O8 CCN1CC2(CCC(C34C2CC(C31)C5(CC(C6CC4C5(C6OC)O)OC)O)OC)OC(=O)C7=CC=CC=C7NC(=O)C Ambient 4°C Soluble in benzene. Slightly soluble in alcohol and ether. Practically insoluble in water. "Ou S, Zhao YD, Xiao Z, et al. Effect of lappaconitine on neuropathic pain mediated by P2X3 receptor in rat dorsal root ganglion. Neurochem Int. 2011 Apr;58(5):564-73. PMID: 21272608.

Wang YZ, Xiao YQ, Zhang C, et al. Study of analgesic and anti-inflammatory effects of lappaconitine gelata. J Tradit Chin Med. 2009 Jun;29(2):141-5. PMID: 19663103.

Wright SN. Irreversible block of human heart (hH1) sodium channels by the plant alkaloid lappaconitine. Mol Pharmacol. 2001 Feb;59(2):183-92. PMID: 11160852.

Heubach JF, Schüle A. Cardiac effects of lappaconitine and N-deacetyllappaconitine, two diterpenoid alkaloids from plants of the Aconitum and Delphinium species. Planta Med. 1998 Feb;64(1):22-6. PMID: 9491764.

Ameri A, Gleitz J, Peters T. Bicuculline-induced epileptiform activity in rat hippocampal slices: suppression by Aconitum alkaloids. Planta Med. 1997 Jun;63(3):228-32. PMID: 9225604.

" "UN number: 1544     Class: 6.1     Packing Group: II

Proper shipping name: Alkaloids, solid, n.o.s. (Lappaconitine)"

LKT L0060 Lappaconitine 500 mg 1270.7 Alkaloid originally found in species of Aconitum; cardiac Na+ channel blocker. (1α,14α,16β)-20-Ethyl-1,14,16-trimethoxyaconitane- 4,8,9-triol 4-[2-(acetylamino)-benzoate] (+)-Lappaconitine 32854-75-4 ≥98% 584.7 C32H44N2O8 CCN1CC2(CCC(C34C2CC(C31)C5(CC(C6CC4C5(C6OC)O)OC)O)OC)OC(=O)C7=CC=CC=C7NC(=O)C Ambient 4°C Soluble in benzene. Slightly soluble in alcohol and ether. Practically insoluble in water. "Ou S, Zhao YD, Xiao Z, et al. Effect of lappaconitine on neuropathic pain mediated by P2X3 receptor in rat dorsal root ganglion. Neurochem Int. 2011 Apr;58(5):564-73. PMID: 21272608.

Wang YZ, Xiao YQ, Zhang C, et al. Study of analgesic and anti-inflammatory effects of lappaconitine gelata. J Tradit Chin Med. 2009 Jun;29(2):141-5. PMID: 19663103.

Wright SN. Irreversible block of human heart (hH1) sodium channels by the plant alkaloid lappaconitine. Mol Pharmacol. 2001 Feb;59(2):183-92. PMID: 11160852.

Heubach JF, Schüle A. Cardiac effects of lappaconitine and N-deacetyllappaconitine, two diterpenoid alkaloids from plants of the Aconitum and Delphinium species. Planta Med. 1998 Feb;64(1):22-6. PMID: 9491764.

Ameri A, Gleitz J, Peters T. Bicuculline-induced epileptiform activity in rat hippocampal slices: suppression by Aconitum alkaloids. Planta Med. 1997 Jun;63(3):228-32. PMID: 9225604.

" "UN number: 1544     Class: 6.1     Packing Group: II

Proper shipping name: Alkaloids, solid, n.o.s. (Lappaconitine)"

LKT L0076 Latrunculin A 100 µg 212.3 76343-93-6 421.55 C22H31NO5S CC1CCC2CC(CC(O2)(C3CSC(=O)N3)O)OC(=O)C=C(CCC=CC=C1)C Ambient 4°C "Helal MA, Khalifa S, Ahmed S. Differential binding of latrunculins to G-actin: a molecular dynamics study. J Chem Inf Model. 2013 Sep 23;53(9):2369-75. PMID: 23988111.

Bartolini F, Ramalingam N, Gundersen GG. Actin-capping protein promotes microtubule stability by antagonizing the actin activity of mDia1. Mol Biol Cell. 2012 Oct;23(20):4032-40. PMID: 22918941.

Rennebaum S, Caflisch A. Inhibition of interdomain motion in g-actin by the natural product latrunculin: a molecular dynamics study. Proteins. 2012 Aug;80(8):1998-2008. PMID: 22488806.

Khanfar MA, Youssef DT, El Sayed KA. Semisynthetic latrunculin derivatives as inhibitors of metastatic breast cancer: biological evaluations, preliminary structure-activity relationship and molecular modeling studies. ChemMedChem. 2010 Feb 1;5(2):274-85. PMID: 20043312.

Sayed KA, Khanfar MA, Shallal HM, et al. Latrunculin A and its C-17-O-carbamates inhibit prostate tumor cell invasion and HIF-1 activation in breast tumor cells. J Nat Prod. 2008 Mar;71(3):396-402. PMID: 18298079.

" Xn Not dangerous goods.

LKT T1777 S,S-(+)-Tetrandrine 100 mg 57.8 Benzylisoquinoline alkaloid originally found in Stephania; voltage-gated Ca2+ channel blocker. (1β)-6,6',7,12-Tetramethoxy-2,2'-dimethylberbaman 518-34-3 ≥98% 622.75 C38H42N2O6 CN1CCC2=CC(=C3C=C2C1CC4=CC=C(C=C4)OC5=C(C=CC(=C5)CC6C7=C(O3)C(=C(C=C7CCN6C)OC)OC)OC)OC Ambient Ambient [α]20/D +290°, c = 1 in chloroform Soluble in ether. Practically insoluble in water. "Sakurai Y, Kolokoltsov AA, Chen CC, et al. Two-pore channels control Ebola virus host cell entry and are drug targets for disease treatment. Science. 2015 Feb 27;347:995-998.

Zhu R, Liu T, Tan Z, et al. Tetrandrine induces apoptosis in gallbladder carcinoma in vitro. Int J Clin Pharmacol Ther. 2014 Jul 30. [Epub ahead of print]. PMID: 25074868.

Zhao H, Luo F, Li H, et al. Antinociceptive effect of tetrandrine on LPS-induced hyperalgesia via the inhibition of IKKβ phosphorylation and the COX-2/PGE₂ pathway in mice. PLoS One. 2014 Apr 10;9(4):e94586. PMID: 24722146.

Ruan L, Huang HS, Jin WX, et al. Tetrandrine attenuated cerebral ischemia/reperfusion injury and induced differential proteomic changes in a MCAO mice model using 2-D DIGE. Neurochem Res. 2013 Sep;38(9):1871-9. PMID: 23780673.

Gao S, Cui YL, Yu CQ, et al. Tetrandrine exerts antidepressant-like effects in animal models: role of brain-derived neurotrophic factor. Behav Brain Res. 2013 Feb 1;238:79-85. PMID: 23085478.

Xu XH, Gan YC, Xu GB, et al. Tetrandrine citrate eliminates imatinib-resistant chronic myeloid leukemia cells in vitro and in vivo by inhibiting Bcr-Abl/β-catenin axis. J Zhejiang Univ Sci B. 2012 Nov;13(11):867-74. PMID: 23125079.

Takahashi T, Tonami Y, Tachibana M, et al. Tetrandrine prevents bone loss in sciatic-neurectomized mice and inhibits receptor activator of nuclear factor κB ligand-induced osteoclast differentiation. Biol Pharm Bull. 2012;35(10):1765-74. PMID: 23037166.

He FQ, Qiu BY, Zhang XH, et al. Tetrandrine attenuates spatial memory impairment and hippocampal neuroinflammation via inhibiting NF-κB activation in a rat model of Alzheimer's disease induced by amyloid-β(1-42). Brain Res. 2011 Apr 12;1384:89-96. PMID: 21300035.

" None Not dangerous goods.

LKT T1777 S,S-(+)-Tetrandrine 500 mg 157.3 Benzylisoquinoline alkaloid originally found in Stephania; voltage-gated Ca2+ channel blocker. (1β)-6,6',7,12-Tetramethoxy-2,2'-dimethylberbaman 518-34-3 ≥98% 622.75 C38H42N2O6 CN1CCC2=CC(=C3C=C2C1CC4=CC=C(C=C4)OC5=C(C=CC(=C5)CC6C7=C(O3)C(=C(C=C7CCN6C)OC)OC)OC)OC Ambient Ambient [α]20/D +290°, c = 1 in chloroform Soluble in ether. Practically insoluble in water. "Sakurai Y, Kolokoltsov AA, Chen CC, et al. Two-pore channels control Ebola virus host cell entry and are drug targets for disease treatment. Science. 2015 Feb 27;347:995-998.

Zhu R, Liu T, Tan Z, et al. Tetrandrine induces apoptosis in gallbladder carcinoma in vitro. Int J Clin Pharmacol Ther. 2014 Jul 30. [Epub ahead of print]. PMID: 25074868.

Zhao H, Luo F, Li H, et al. Antinociceptive effect of tetrandrine on LPS-induced hyperalgesia via the inhibition of IKKβ phosphorylation and the COX-2/PGE₂ pathway in mice. PLoS One. 2014 Apr 10;9(4):e94586. PMID: 24722146.

Ruan L, Huang HS, Jin WX, et al. Tetrandrine attenuated cerebral ischemia/reperfusion injury and induced differential proteomic changes in a MCAO mice model using 2-D DIGE. Neurochem Res. 2013 Sep;38(9):1871-9. PMID: 23780673.

Gao S, Cui YL, Yu CQ, et al. Tetrandrine exerts antidepressant-like effects in animal models: role of brain-derived neurotrophic factor. Behav Brain Res. 2013 Feb 1;238:79-85. PMID: 23085478.

Xu XH, Gan YC, Xu GB, et al. Tetrandrine citrate eliminates imatinib-resistant chronic myeloid leukemia cells in vitro and in vivo by inhibiting Bcr-Abl/β-catenin axis. J Zhejiang Univ Sci B. 2012 Nov;13(11):867-74. PMID: 23125079.

Takahashi T, Tonami Y, Tachibana M, et al. Tetrandrine prevents bone loss in sciatic-neurectomized mice and inhibits receptor activator of nuclear factor κB ligand-induced osteoclast differentiation. Biol Pharm Bull. 2012;35(10):1765-74. PMID: 23037166.

He FQ, Qiu BY, Zhang XH, et al. Tetrandrine attenuates spatial memory impairment and hippocampal neuroinflammation via inhibiting NF-κB activation in a rat model of Alzheimer's disease induced by amyloid-β(1-42). Brain Res. 2011 Apr 12;1384:89-96. PMID: 21300035.

" None Not dangerous goods.

LKT T1777 S,S-(+)-Tetrandrine 1 g 242.6 Benzylisoquinoline alkaloid originally found in Stephania; voltage-gated Ca2+ channel blocker. (1β)-6,6',7,12-Tetramethoxy-2,2'-dimethylberbaman 518-34-3 ≥98% 622.75 C38H42N2O6 CN1CCC2=CC(=C3C=C2C1CC4=CC=C(C=C4)OC5=C(C=CC(=C5)CC6C7=C(O3)C(=C(C=C7CCN6C)OC)OC)OC)OC Ambient Ambient [α]20/D +290°, c = 1 in chloroform Soluble in ether. Practically insoluble in water. "Sakurai Y, Kolokoltsov AA, Chen CC, et al. Two-pore channels control Ebola virus host cell entry and are drug targets for disease treatment. Science. 2015 Feb 27;347:995-998.

Zhu R, Liu T, Tan Z, et al. Tetrandrine induces apoptosis in gallbladder carcinoma in vitro. Int J Clin Pharmacol Ther. 2014 Jul 30. [Epub ahead of print]. PMID: 25074868.

Zhao H, Luo F, Li H, et al. Antinociceptive effect of tetrandrine on LPS-induced hyperalgesia via the inhibition of IKKβ phosphorylation and the COX-2/PGE₂ pathway in mice. PLoS One. 2014 Apr 10;9(4):e94586. PMID: 24722146.

Ruan L, Huang HS, Jin WX, et al. Tetrandrine attenuated cerebral ischemia/reperfusion injury and induced differential proteomic changes in a MCAO mice model using 2-D DIGE. Neurochem Res. 2013 Sep;38(9):1871-9. PMID: 23780673.

Gao S, Cui YL, Yu CQ, et al. Tetrandrine exerts antidepressant-like effects in animal models: role of brain-derived neurotrophic factor. Behav Brain Res. 2013 Feb 1;238:79-85. PMID: 23085478.

Xu XH, Gan YC, Xu GB, et al. Tetrandrine citrate eliminates imatinib-resistant chronic myeloid leukemia cells in vitro and in vivo by inhibiting Bcr-Abl/β-catenin axis. J Zhejiang Univ Sci B. 2012 Nov;13(11):867-74. PMID: 23125079.

Takahashi T, Tonami Y, Tachibana M, et al. Tetrandrine prevents bone loss in sciatic-neurectomized mice and inhibits receptor activator of nuclear factor κB ligand-induced osteoclast differentiation. Biol Pharm Bull. 2012;35(10):1765-74. PMID: 23037166.

He FQ, Qiu BY, Zhang XH, et al. Tetrandrine attenuates spatial memory impairment and hippocampal neuroinflammation via inhibiting NF-κB activation in a rat model of Alzheimer's disease induced by amyloid-β(1-42). Brain Res. 2011 Apr 12;1384:89-96. PMID: 21300035.

" None Not dangerous goods.

LKT T1754 Tenatoprazole 100 mg 81 H+/K+ ATPase inhibitor. 5-Methoxy-2--1H-imidazo[4,5-b]pyridine Protop; Ulsacare 113712-98-4 ≥98% 346.41 C16H18N4O3S CC1=CN=C(C(=C1OC)C)CS(=O)C2=NC3=C(N2)C=CC(=N3)OC Ambient 4°C Soluble in dichlormethane. "Li H, Meng L, Liu F, et al. H+/K+-ATPase inhibitors: a patent review. Expert Opin Ther Pat. 2013 Jan;23(1):99-111. PMID: 23205582.

Shin JM, Homerin M, Domagala F, et al. Characterization of the inhibitory activity of tenatoprazole on the gastric H+,K+ -ATPase in vitro and in vivo. Biochem Pharmacol. 2006 Mar 14;71(6):837-49. PMID: 16405921.

" Xn, Xi Not dangerous goods.

LKT T1754 Tenatoprazole 500 mg 242.6 H+/K+ ATPase inhibitor. 5-Methoxy-2--1H-imidazo[4,5-b]pyridine Protop; Ulsacare 113712-98-4 ≥98% 346.41 C16H18N4O3S CC1=CN=C(C(=C1OC)C)CS(=O)C2=NC3=C(N2)C=CC(=N3)OC Ambient 4°C Soluble in dichlormethane. "Li H, Meng L, Liu F, et al. H+/K+-ATPase inhibitors: a patent review. Expert Opin Ther Pat. 2013 Jan;23(1):99-111. PMID: 23205582.

Shin JM, Homerin M, Domagala F, et al. Characterization of the inhibitory activity of tenatoprazole on the gastric H+,K+ -ATPase in vitro and in vivo. Biochem Pharmacol. 2006 Mar 14;71(6):837-49. PMID: 16405921.

" Xn, Xi Not dangerous goods.

LKT T1754 Tenatoprazole 1 g 388.2 H+/K+ ATPase inhibitor. 5-Methoxy-2--1H-imidazo[4,5-b]pyridine Protop; Ulsacare 113712-98-4 ≥98% 346.41 C16H18N4O3S CC1=CN=C(C(=C1OC)C)CS(=O)C2=NC3=C(N2)C=CC(=N3)OC Ambient 4°C Soluble in dichlormethane. "Li H, Meng L, Liu F, et al. H+/K+-ATPase inhibitors: a patent review. Expert Opin Ther Pat. 2013 Jan;23(1):99-111. PMID: 23205582.

Shin JM, Homerin M, Domagala F, et al. Characterization of the inhibitory activity of tenatoprazole on the gastric H+,K+ -ATPase in vitro and in vivo. Biochem Pharmacol. 2006 Mar 14;71(6):837-49. PMID: 16405921.

" Xn, Xi Not dangerous goods.

LKT T1750 Temocapril Hydrochloride 10 mg 95.1 ACE inhibitor. CS-622 110221-44-8 ≥98% 513.07 C23H28N2O5S2 HCl CCOC(=O)C(CCC1=CC=CC=C1)NC2CSC(CN(C2=O)CC(=O)O)C3=CC=CS3.Cl Ambient Ambient "Yamamoto D, Takai S, Akimoto T, et al. Matrix metalloproteinase-2 inhibition by temocapril and its important role in peritoneal transport. Clin Exp Pharmacol Physiol. 2012 Oct;39(10):864-8. PMID: 23013132.

Kaihara M, Nakamura Y, Sugimoto T, et al. Olmesartan and temocapril prevented the development of hyperglycemia and the deterioration of pancreatic islet morphology in Otsuka-Long-Evans-Tokushima Fatty rats. Acta Med Okayama. 2009 Feb;63(1):35-42. PMID: 19247421.

Nozawa M, Sugimoto K, Ohmori M, et al. Dosing time-dependent effect of temocapril on the mortality of stroke-prone spontaneously hypertensive rats. J Pharmacol Exp Ther. 2006 Jan;316(1):176-81. PMID: 16174798.

Tsuda M, Iwai M, Li JM, et al. Inhibitory effects of AT1 receptor blocker, olmesartan, and estrogen on atherosclerosis via anti-oxidative stress. Hypertension. 2005 Apr;45(4):545-51. PMID: 15723967.

Yasunari K, Maeda K, Nakamura M, et al. Pharmacological and clinical studies with temocapril, an angiotensin converting enzyme inhibitor that is excreted in the bile. Cardiovasc Drug Rev. 2004 Fall;22(3):189-98. PMID: 15492767.

Oizumi K, Koike H, Sada T, et al. Pharmacological profiles of CS-622, a novel angiotensin converting enzyme inhibitor. Jpn J Pharmacol. 1988 Nov;48(3):349-56. PMID: 2851680.

" Not dangerous goods.

LKT T1750 Temocapril Hydrochloride 25 mg 149.5 ACE inhibitor. CS-622 110221-44-8 ≥98% 513.07 C23H28N2O5S2 HCl CCOC(=O)C(CCC1=CC=CC=C1)NC2CSC(CN(C2=O)CC(=O)O)C3=CC=CS3.Cl Ambient Ambient "Yamamoto D, Takai S, Akimoto T, et al. Matrix metalloproteinase-2 inhibition by temocapril and its important role in peritoneal transport. Clin Exp Pharmacol Physiol. 2012 Oct;39(10):864-8. PMID: 23013132.

Kaihara M, Nakamura Y, Sugimoto T, et al. Olmesartan and temocapril prevented the development of hyperglycemia and the deterioration of pancreatic islet morphology in Otsuka-Long-Evans-Tokushima Fatty rats. Acta Med Okayama. 2009 Feb;63(1):35-42. PMID: 19247421.

Nozawa M, Sugimoto K, Ohmori M, et al. Dosing time-dependent effect of temocapril on the mortality of stroke-prone spontaneously hypertensive rats. J Pharmacol Exp Ther. 2006 Jan;316(1):176-81. PMID: 16174798.

Tsuda M, Iwai M, Li JM, et al. Inhibitory effects of AT1 receptor blocker, olmesartan, and estrogen on atherosclerosis via anti-oxidative stress. Hypertension. 2005 Apr;45(4):545-51. PMID: 15723967.

Yasunari K, Maeda K, Nakamura M, et al. Pharmacological and clinical studies with temocapril, an angiotensin converting enzyme inhibitor that is excreted in the bile. Cardiovasc Drug Rev. 2004 Fall;22(3):189-98. PMID: 15492767.

Oizumi K, Koike H, Sada T, et al. Pharmacological profiles of CS-622, a novel angiotensin converting enzyme inhibitor. Jpn J Pharmacol. 1988 Nov;48(3):349-56. PMID: 2851680.

" Not dangerous goods.

LKT T1750 Temocapril Hydrochloride 100 mg 434.9 ACE inhibitor. CS-622 110221-44-8 ≥98% 513.07 C23H28N2O5S2 HCl CCOC(=O)C(CCC1=CC=CC=C1)NC2CSC(CN(C2=O)CC(=O)O)C3=CC=CS3.Cl Ambient Ambient "Yamamoto D, Takai S, Akimoto T, et al. Matrix metalloproteinase-2 inhibition by temocapril and its important role in peritoneal transport. Clin Exp Pharmacol Physiol. 2012 Oct;39(10):864-8. PMID: 23013132.

Kaihara M, Nakamura Y, Sugimoto T, et al. Olmesartan and temocapril prevented the development of hyperglycemia and the deterioration of pancreatic islet morphology in Otsuka-Long-Evans-Tokushima Fatty rats. Acta Med Okayama. 2009 Feb;63(1):35-42. PMID: 19247421.

Nozawa M, Sugimoto K, Ohmori M, et al. Dosing time-dependent effect of temocapril on the mortality of stroke-prone spontaneously hypertensive rats. J Pharmacol Exp Ther. 2006 Jan;316(1):176-81. PMID: 16174798.

Tsuda M, Iwai M, Li JM, et al. Inhibitory effects of AT1 receptor blocker, olmesartan, and estrogen on atherosclerosis via anti-oxidative stress. Hypertension. 2005 Apr;45(4):545-51. PMID: 15723967.

Yasunari K, Maeda K, Nakamura M, et al. Pharmacological and clinical studies with temocapril, an angiotensin converting enzyme inhibitor that is excreted in the bile. Cardiovasc Drug Rev. 2004 Fall;22(3):189-98. PMID: 15492767.

Oizumi K, Koike H, Sada T, et al. Pharmacological profiles of CS-622, a novel angiotensin converting enzyme inhibitor. Jpn J Pharmacol. 1988 Nov;48(3):349-56. PMID: 2851680.

" Not dangerous goods.

LKT L0209 Lactoferrin, cow 10 mg 89.7 Endogenous glycoprotein; lactoferrin agonist. Lactotransferrin 146897-68-9 ≥92% 90 "CCC(C)C(C(=O)NC(C(C)O)C(=O)NC(CS)C(=O)NC(C(C)C)C(=O)NC(CCCNC(=N)N)C(=O)NC(CCCNC(=N)N)C(=O)NC(C)C(=O)NC(Cc1ccccc1)C(=O)O)NC(=O)C(CO)NC(=O)C2CCCN2C(=O)C(C)NC(=O)CNC(=O)C(CC(C)C)NC(=O)C(CCCCN)NC(=O)C(CCCCN)NC(=O)C(CCSC)NC(=O)C(CCCNC(=N)N)NC(=O)C(Cc3c[nH]c4c3cccc4)NC(=O)C(CCC(=O)N)NC(=O)C(Cc5c[nH]c6c5cccc6)NC(=O)C(CCCNC(=N)N)NC(=O)C(CCCNC(=N)N)NC(=O)C(CS)NC(=O)C(CCCCN)NC(=O)C(Cc7ccccc7)N

" Ambient -20°C Soluble in water (2% w/v). "Farnaud S, Evans RW. Lactoferrin--a multifunctional protein with antimicrobial properties. Mol Immunol. 2003 Nov;40(7):395-405. PMID: 14568385.

Viejo-Díaz M, Andrés MT, Fierro JF. Modulation of in vitro fungicidal activity of human lactoferrin against Candida albicans by extracellular cation concentration and target cell metabolic activity. Antimicrob Agents Chemother. 2004 Apr;48(4):1242-8. PMID: 15047526.

Tsuda H, Sekine K, Fujita K, et al. Cancer prevention by bovine lactoferrin and underlying mechanisms--a review of experimental and clinical studies. Biochem Cell Biol. 2002;80(1):131-6. PMID: 11908637.

van der Strate BW, Beljaars L, Molema G, et al. Antiviral activities of lactoferrin. Antiviral Res. 2001 Dec;52(3):225-39. PMID: 11675140.

Xanthou M. Immune protection of human milk. Biol Neonate. 1998;74(2):121-33. PMID: 9691154.

Harmsen MC, Swart PJ, de Béthune MP, et al. Antiviral effects of plasma and milk proteins: lactoferrin shows potent activity against both human immunodeficiency virus and human cytomegalovirus replication in vitro. J Infect Dis. 1995 Aug;172(2):380-8. PMID: 7622881.

Bennett RM, Davis J. Lactoferrin interacts with deoxyribonucleic acid: a preferential reactivity with double-stranded DNA and dissociation of DNA-anti-DNA complexes. J Lab Clin Med. 1982 Jan;99(1):127-38. PMID: 6274982.

" Not dangerous goods

LKT L0209 Lactoferrin, cow 50 mg 336.4 Endogenous glycoprotein; lactoferrin agonist. Lactotransferrin 146897-68-9 ≥92% 90 "CCC(C)C(C(=O)NC(C(C)O)C(=O)NC(CS)C(=O)NC(C(C)C)C(=O)NC(CCCNC(=N)N)C(=O)NC(CCCNC(=N)N)C(=O)NC(C)C(=O)NC(Cc1ccccc1)C(=O)O)NC(=O)C(CO)NC(=O)C2CCCN2C(=O)C(C)NC(=O)CNC(=O)C(CC(C)C)NC(=O)C(CCCCN)NC(=O)C(CCCCN)NC(=O)C(CCSC)NC(=O)C(CCCNC(=N)N)NC(=O)C(Cc3c[nH]c4c3cccc4)NC(=O)C(CCC(=O)N)NC(=O)C(Cc5c[nH]c6c5cccc6)NC(=O)C(CCCNC(=N)N)NC(=O)C(CCCNC(=N)N)NC(=O)C(CS)NC(=O)C(CCCCN)NC(=O)C(Cc7ccccc7)N

" Ambient -20°C Soluble in water (2% w/v). "Farnaud S, Evans RW. Lactoferrin--a multifunctional protein with antimicrobial properties. Mol Immunol. 2003 Nov;40(7):395-405. PMID: 14568385.

Viejo-Díaz M, Andrés MT, Fierro JF. Modulation of in vitro fungicidal activity of human lactoferrin against Candida albicans by extracellular cation concentration and target cell metabolic activity. Antimicrob Agents Chemother. 2004 Apr;48(4):1242-8. PMID: 15047526.

Tsuda H, Sekine K, Fujita K, et al. Cancer prevention by bovine lactoferrin and underlying mechanisms--a review of experimental and clinical studies. Biochem Cell Biol. 2002;80(1):131-6. PMID: 11908637.

van der Strate BW, Beljaars L, Molema G, et al. Antiviral activities of lactoferrin. Antiviral Res. 2001 Dec;52(3):225-39. PMID: 11675140.

Xanthou M. Immune protection of human milk. Biol Neonate. 1998;74(2):121-33. PMID: 9691154.

Harmsen MC, Swart PJ, de Béthune MP, et al. Antiviral effects of plasma and milk proteins: lactoferrin shows potent activity against both human immunodeficiency virus and human cytomegalovirus replication in vitro. J Infect Dis. 1995 Aug;172(2):380-8. PMID: 7622881.

Bennett RM, Davis J. Lactoferrin interacts with deoxyribonucleic acid: a preferential reactivity with double-stranded DNA and dissociation of DNA-anti-DNA complexes. J Lab Clin Med. 1982 Jan;99(1):127-38. PMID: 6274982.

" Not dangerous goods

LKT L0209 Lactoferrin, cow 100 mg 515.7 Endogenous glycoprotein; lactoferrin agonist. Lactotransferrin 146897-68-9 ≥92% 90 "CCC(C)C(C(=O)NC(C(C)O)C(=O)NC(CS)C(=O)NC(C(C)C)C(=O)NC(CCCNC(=N)N)C(=O)NC(CCCNC(=N)N)C(=O)NC(C)C(=O)NC(Cc1ccccc1)C(=O)O)NC(=O)C(CO)NC(=O)C2CCCN2C(=O)C(C)NC(=O)CNC(=O)C(CC(C)C)NC(=O)C(CCCCN)NC(=O)C(CCCCN)NC(=O)C(CCSC)NC(=O)C(CCCNC(=N)N)NC(=O)C(Cc3c[nH]c4c3cccc4)NC(=O)C(CCC(=O)N)NC(=O)C(Cc5c[nH]c6c5cccc6)NC(=O)C(CCCNC(=N)N)NC(=O)C(CCCNC(=N)N)NC(=O)C(CS)NC(=O)C(CCCCN)NC(=O)C(Cc7ccccc7)N

" Ambient -20°C Soluble in water (2% w/v). "Farnaud S, Evans RW. Lactoferrin--a multifunctional protein with antimicrobial properties. Mol Immunol. 2003 Nov;40(7):395-405. PMID: 14568385.

Viejo-Díaz M, Andrés MT, Fierro JF. Modulation of in vitro fungicidal activity of human lactoferrin against Candida albicans by extracellular cation concentration and target cell metabolic activity. Antimicrob Agents Chemother. 2004 Apr;48(4):1242-8. PMID: 15047526.

Tsuda H, Sekine K, Fujita K, et al. Cancer prevention by bovine lactoferrin and underlying mechanisms--a review of experimental and clinical studies. Biochem Cell Biol. 2002;80(1):131-6. PMID: 11908637.

van der Strate BW, Beljaars L, Molema G, et al. Antiviral activities of lactoferrin. Antiviral Res. 2001 Dec;52(3):225-39. PMID: 11675140.

Xanthou M. Immune protection of human milk. Biol Neonate. 1998;74(2):121-33. PMID: 9691154.

Harmsen MC, Swart PJ, de Béthune MP, et al. Antiviral effects of plasma and milk proteins: lactoferrin shows potent activity against both human immunodeficiency virus and human cytomegalovirus replication in vitro. J Infect Dis. 1995 Aug;172(2):380-8. PMID: 7622881.

Bennett RM, Davis J. Lactoferrin interacts with deoxyribonucleic acid: a preferential reactivity with double-stranded DNA and dissociation of DNA-anti-DNA complexes. J Lab Clin Med. 1982 Jan;99(1):127-38. PMID: 6274982.

" Not dangerous goods

LKT T1679 Tetracycline Hydrochloride 1 g 27.2 Polyketide; protein translation inhibitor, mammalian RNA splicing inhibitor, potential MMP inhibitor. [4S-(4α, 4aα, 5aα,6β,12aα)]-4-(Dimethylamino)- 1,4,4a,5,5a,6-11,12a-octahydro-3,6,10,12,12a-penta- hydroxy-6-methyl-1,11-dioxo-2-naphthacene- carboxamide hydrochloride Achromycin; Panmycin; Topicycline; Cylcopar; Diocyclin 64-75-5 ≥96% 480.9 C22H24N2O8 HCl CC1(C2CC3C(C(=O)C(=C(C3(C(=O)C2=C(C4=C1C=CC=C4O)O)O)O)C(=O)N)N(C)C)O.Cl Ambient 4°C Soluble in water (100 mg/mL), methanol and ethanol (10 mg/mL). Insoluble in ether and hydrocarbons. "Kennedy R, Alibhai M, Shakib K. Tetracycline: a cure all? Br J Oral Maxillofac Surg. 2014 Apr;52(4):382-3. PMID: 24613100.

Mahajan GB, Balachandran L. Antibacterial agents from actinomycetes - a review. Front Biosci (Elite Ed). 2012 Jan 1;4:240-53. PMID: 22201868.

Airoldi C, Colombo L, Manzoni C, et al. Tetracycline prevents Aβ oligomer toxicity through an atypical supramolecular interaction. Org Biomol Chem. 2011 Jan 21;9(2):463-72. PMID: 21063627.

Griffin MO, Fricovsky E, Ceballos G, et al. Tetracyclines: a pleitropic family of compounds with promising therapeutic properties. Review of the literature. Am J Physiol Cell Physiol. 2010 Sep;299(3):C539-48. PMID: 20592239.

Hertweck M, Hiller R, Mueller MW. Inhibition of nuclear pre-mRNA splicing by antibiotics in vitro. Eur J Biochem. 2002 Jan;269(1):175-83. PMID: 11784311." Not dangerous goods.

LKT L0211 Lactulose 10 g 104.6 Synthetic non-digestible disaccharide. 4-O-b-D-Galactopyranosyl-D-fructose Bifiteral; Cephulac; Generlac, Lactuflor; Normase 4618-18-2 ≥98% 342.3 C12H22O11 C(C1C(C(C(C(O1)OC2C(OC(C2O)(CO)O)CO)O)O)O)O Ambient Ambient Soluble in water. "Panesar PS, Kumari S. Lactulose: production, purification and potential applications. Biotechnol Adv. 2011 Nov-Dec;29(6):940-8. PMID: 21856402.

Shukla S, Shukla A, Mehboob S, et al. Meta-analysis: the effects of gut flora modulation using prebiotics, probiotics and synbiotics on minimal hepatic encephalopathy. Aliment Pharmacol Ther. 2011 Mar;33(6):662-71. PMID: 21251030.

" Not dangerous goods.

LKT T1679 Tetracycline Hydrochloride 5 g 40.7 Polyketide; protein translation inhibitor, mammalian RNA splicing inhibitor, potential MMP inhibitor. [4S-(4α, 4aα, 5aα,6β,12aα)]-4-(Dimethylamino)- 1,4,4a,5,5a,6-11,12a-octahydro-3,6,10,12,12a-penta- hydroxy-6-methyl-1,11-dioxo-2-naphthacene- carboxamide hydrochloride Achromycin; Panmycin; Topicycline; Cylcopar; Diocyclin 64-75-5 ≥96% 480.9 C22H24N2O8 HCl CC1(C2CC3C(C(=O)C(=C(C3(C(=O)C2=C(C4=C1C=CC=C4O)O)O)O)C(=O)N)N(C)C)O.Cl Ambient 4°C Soluble in water (100 mg/mL), methanol and ethanol (10 mg/mL). Insoluble in ether and hydrocarbons. "Kennedy R, Alibhai M, Shakib K. Tetracycline: a cure all? Br J Oral Maxillofac Surg. 2014 Apr;52(4):382-3. PMID: 24613100.

Mahajan GB, Balachandran L. Antibacterial agents from actinomycetes - a review. Front Biosci (Elite Ed). 2012 Jan 1;4:240-53. PMID: 22201868.

Airoldi C, Colombo L, Manzoni C, et al. Tetracycline prevents Aβ oligomer toxicity through an atypical supramolecular interaction. Org Biomol Chem. 2011 Jan 21;9(2):463-72. PMID: 21063627.

Griffin MO, Fricovsky E, Ceballos G, et al. Tetracyclines: a pleitropic family of compounds with promising therapeutic properties. Review of the literature. Am J Physiol Cell Physiol. 2010 Sep;299(3):C539-48. PMID: 20592239.

Hertweck M, Hiller R, Mueller MW. Inhibition of nuclear pre-mRNA splicing by antibiotics in vitro. Eur J Biochem. 2002 Jan;269(1):175-83. PMID: 11784311." Not dangerous goods.

LKT L0211 Lactulose 25 g 209.3 Synthetic non-digestible disaccharide. 4-O-b-D-Galactopyranosyl-D-fructose Bifiteral; Cephulac; Generlac, Lactuflor; Normase 4618-18-2 ≥98% 342.3 C12H22O11 C(C1C(C(C(C(O1)OC2C(OC(C2O)(CO)O)CO)O)O)O)O Ambient Ambient Soluble in water. "Panesar PS, Kumari S. Lactulose: production, purification and potential applications. Biotechnol Adv. 2011 Nov-Dec;29(6):940-8. PMID: 21856402.

Shukla S, Shukla A, Mehboob S, et al. Meta-analysis: the effects of gut flora modulation using prebiotics, probiotics and synbiotics on minimal hepatic encephalopathy. Aliment Pharmacol Ther. 2011 Mar;33(6):662-71. PMID: 21251030.

" Not dangerous goods.

LKT T1679 Tetracycline Hydrochloride 25 g 163.2 Polyketide; protein translation inhibitor, mammalian RNA splicing inhibitor, potential MMP inhibitor. [4S-(4α, 4aα, 5aα,6β,12aα)]-4-(Dimethylamino)- 1,4,4a,5,5a,6-11,12a-octahydro-3,6,10,12,12a-penta- hydroxy-6-methyl-1,11-dioxo-2-naphthacene- carboxamide hydrochloride Achromycin; Panmycin; Topicycline; Cylcopar; Diocyclin 64-75-5 ≥96% 480.9 C22H24N2O8 HCl CC1(C2CC3C(C(=O)C(=C(C3(C(=O)C2=C(C4=C1C=CC=C4O)O)O)O)C(=O)N)N(C)C)O.Cl Ambient 4°C Soluble in water (100 mg/mL), methanol and ethanol (10 mg/mL). Insoluble in ether and hydrocarbons. "Kennedy R, Alibhai M, Shakib K. Tetracycline: a cure all? Br J Oral Maxillofac Surg. 2014 Apr;52(4):382-3. PMID: 24613100.

Mahajan GB, Balachandran L. Antibacterial agents from actinomycetes - a review. Front Biosci (Elite Ed). 2012 Jan 1;4:240-53. PMID: 22201868.

Airoldi C, Colombo L, Manzoni C, et al. Tetracycline prevents Aβ oligomer toxicity through an atypical supramolecular interaction. Org Biomol Chem. 2011 Jan 21;9(2):463-72. PMID: 21063627.

Griffin MO, Fricovsky E, Ceballos G, et al. Tetracyclines: a pleitropic family of compounds with promising therapeutic properties. Review of the literature. Am J Physiol Cell Physiol. 2010 Sep;299(3):C539-48. PMID: 20592239.

Hertweck M, Hiller R, Mueller MW. Inhibition of nuclear pre-mRNA splicing by antibiotics in vitro. Eur J Biochem. 2002 Jan;269(1):175-83. PMID: 11784311." Not dangerous goods.

LKT L0226 Lagochiline 25 mg 115.5 Diterpene alkaloid found in Lagochilus. ≥98% 356.6 C20H36O5 CC1CCC2C(C13CCC(O3)(CCO)CO)(CCC(C2(C)CO)O)C Store in a dark place. Ambient 4°C Soluble in organic solvents. Pulatova TP, Khazanovich RL. On the alkaloid content of some Lagochilus species and on the nature of lagochiline. Aptechn Delo. 1962 Nov-Dec;6:29-32. PMID: 13972488. Not dangerous goods.

LKT L0226 Lagochiline 100 mg 381.3 Diterpene alkaloid found in Lagochilus. ≥98% 356.6 C20H36O5 CC1CCC2C(C13CCC(O3)(CCO)CO)(CCC(C2(C)CO)O)C Store in a dark place. Ambient 4°C Soluble in organic solvents. Pulatova TP, Khazanovich RL. On the alkaloid content of some Lagochilus species and on the nature of lagochiline. Aptechn Delo. 1962 Nov-Dec;6:29-32. PMID: 13972488. Not dangerous goods.

LKT T1678 D,L-Tetrahydropalmatine 100 mg 68.8 Alkaloid found in Corydalis and Stephania; D1/2 antagonist, potential L-type Ca2+ and K+ channel blocker. 5,8,13,13a-Tetrahydro-2,3,9,10-tetramethoxy-6H- dibenzo[a,g]quinolizine Tetrahydropalmatine; Hynndarin 10097-84-4 ≥98% 355.43 C21H25NO4 COC1=C(C2=C(CC3C4=CC(=C(C=C4CCN3C2)OC)OC)C=C1)OC Ambient Ambient "Baghdikian B, Mahiou-Leddet V, Bory S, et al. New antiplasmodial alkaloids from Stephania rotunda. J Ethnopharmacol. 2013 Jan 9;145(1):381-5. PMID: 23127648.

Cao FL, Shang GW, Wang Y, et al. Antinociceptive effects of intragastric DL-tetrahydropalmatine on visceral and somatic persistent nociception and pain hypersensitivity in rats. Pharmacol Biochem Behav. 2011 Nov;100(1):199-204. PMID: 21889526.

Henkes H, Franz M, Kendall O, et al. Evaluation of the anxiolytic properties of tetrahydropalmatine, a Corydalis yanhusuo compound, in the male Sprague-Dawley rat. AANA J. 2011 Aug;79(4 Suppl):S75-80. PMID: 22403971.

" Not dangerous goods.

LKT L0248 Laminin Peptide YIGSR 1 mg 64.6 Laminin-derived peptapeptide. 110590-64-2 ≥98% 594.66 C26H42N8O8 CCC(C)C(C(=O)NCC(=O)NC(CO)C(=O)NC(CCCNC(=N)N)C(=O)O)NC(=O)C(Cc1ccc(cc1)O)N Store in a cool, dry place. Ambient -20°C "Yoon JH, Kim J, Lee H, et al. Laminin peptide YIGSR induces collagen synthesis in Hs27 human dermal fibroblasts. Biochem Biophys Res Commun. 2012 Nov 23;428(3):416-21. PMID: 23111328.

Dubey PK, Singodia D, Vyas SP. Polymeric nanospheres modified with YIGSR peptide for tumor targeting. Drug Deliv. 2010 Sep-Oct;17(7):541-51. PMID: 20560774.

Yu HN, Zhang LC, Yang JG, et al. Effect of laminin tyrosine-isoleucine-glycine-serine-arginine peptide on the growth of human prostate cancer (PC-3) cells in vitro. Eur J Pharmacol. 2009 Aug 15;616(1-3):251-5. PMID: 19577562.

" Not dangerous goods.

LKT L0248 Laminin Peptide YIGSR 5 mg 208 Laminin-derived peptapeptide. 110590-64-2 ≥98% 594.66 C26H42N8O8 CCC(C)C(C(=O)NCC(=O)NC(CO)C(=O)NC(CCCNC(=N)N)C(=O)O)NC(=O)C(Cc1ccc(cc1)O)N Store in a cool, dry place. Ambient -20°C "Yoon JH, Kim J, Lee H, et al. Laminin peptide YIGSR induces collagen synthesis in Hs27 human dermal fibroblasts. Biochem Biophys Res Commun. 2012 Nov 23;428(3):416-21. PMID: 23111328.

Dubey PK, Singodia D, Vyas SP. Polymeric nanospheres modified with YIGSR peptide for tumor targeting. Drug Deliv. 2010 Sep-Oct;17(7):541-51. PMID: 20560774.

Yu HN, Zhang LC, Yang JG, et al. Effect of laminin tyrosine-isoleucine-glycine-serine-arginine peptide on the growth of human prostate cancer (PC-3) cells in vitro. Eur J Pharmacol. 2009 Aug 15;616(1-3):251-5. PMID: 19577562.

" Not dangerous goods.

LKT T1678 D,L-Tetrahydropalmatine 500 mg 252.6 Alkaloid found in Corydalis and Stephania; D1/2 antagonist, potential L-type Ca2+ and K+ channel blocker. 5,8,13,13a-Tetrahydro-2,3,9,10-tetramethoxy-6H- dibenzo[a,g]quinolizine Tetrahydropalmatine; Hynndarin 10097-84-4 ≥98% 355.43 C21H25NO4 COC1=C(C2=C(CC3C4=CC(=C(C=C4CCN3C2)OC)OC)C=C1)OC Ambient Ambient "Baghdikian B, Mahiou-Leddet V, Bory S, et al. New antiplasmodial alkaloids from Stephania rotunda. J Ethnopharmacol. 2013 Jan 9;145(1):381-5. PMID: 23127648.

Cao FL, Shang GW, Wang Y, et al. Antinociceptive effects of intragastric DL-tetrahydropalmatine on visceral and somatic persistent nociception and pain hypersensitivity in rats. Pharmacol Biochem Behav. 2011 Nov;100(1):199-204. PMID: 21889526.

Henkes H, Franz M, Kendall O, et al. Evaluation of the anxiolytic properties of tetrahydropalmatine, a Corydalis yanhusuo compound, in the male Sprague-Dawley rat. AANA J. 2011 Aug;79(4 Suppl):S75-80. PMID: 22403971.

" Not dangerous goods.

LKT L0249 Laminin Peptide YIGSR-NH2 1 mg 74 Laminin-derived peptapeptide. ≥98% 593.67 C26H43N9O7 Store in a cool, dry place. Ambient -20°C "Yoon JH, Kim J, Lee H, et al. Laminin peptide YIGSR induces collagen synthesis in Hs27 human dermal fibroblasts. Biochem Biophys Res Commun. 2012 Nov 23;428(3):416-21. PMID: 23111328.

Dubey PK, Singodia D, Vyas SP. Polymeric nanospheres modified with YIGSR peptide for tumor targeting. Drug Deliv. 2010 Sep-Oct;17(7):541-51. PMID: 20560774.

Yu HN, Zhang LC, Yang JG, et al. Effect of laminin tyrosine-isoleucine-glycine-serine-arginine peptide on the growth of human prostate cancer (PC-3) cells in vitro. Eur J Pharmacol. 2009 Aug 15;616(1-3):251-5. PMID: 19577562.

" Not dangerous goods.

LKT L0249 Laminin Peptide YIGSR-NH2 5 mg 277.4 Laminin-derived peptapeptide. ≥98% 593.67 C26H43N9O7 Store in a cool, dry place. Ambient -20°C "Yoon JH, Kim J, Lee H, et al. Laminin peptide YIGSR induces collagen synthesis in Hs27 human dermal fibroblasts. Biochem Biophys Res Commun. 2012 Nov 23;428(3):416-21. PMID: 23111328.

Dubey PK, Singodia D, Vyas SP. Polymeric nanospheres modified with YIGSR peptide for tumor targeting. Drug Deliv. 2010 Sep-Oct;17(7):541-51. PMID: 20560774.

Yu HN, Zhang LC, Yang JG, et al. Effect of laminin tyrosine-isoleucine-glycine-serine-arginine peptide on the growth of human prostate cancer (PC-3) cells in vitro. Eur J Pharmacol. 2009 Aug 15;616(1-3):251-5. PMID: 19577562.

" Not dangerous goods.

LKT T1677 Tetracycline 10 g 43.5 Polyketide; protein translation inhibitor, mammalian RNA splicing inhibitor, potential MMP inhibitor. [4S-(4α,4aα,5aα,6b,12aα)]-4-(Dimethylamino)-1,4,4a,-5,5a,6-11,12a-octahydro-3,6,10,12,12a-pentahydroxy-6-methyl-1,11-dioxo-2-naphthacenecarboxamide Deschlorobiomycin; Ambramycin; Liquamycin 60-54-8 ≥90% 444.43 C22H24N2O8 CC1(C2CC3C(C(=O)C(=C(C3(C(=O)C2=C(C4=C1C=CC=C4O)O)O)O)C(=O)N)N(C)C)O Ambient 4°C Soluble in methanol or ethanol (20 mg/mL). Slightly soluble in water (0.4 mg/mL). "Kennedy R, Alibhai M, Shakib K. Tetracycline: a cure all? Br J Oral Maxillofac Surg. 2014 Apr;52(4):382-3. PMID: 24613100.

Mahajan GB, Balachandran L. Antibacterial agents from actinomycetes - a review. Front Biosci (Elite Ed). 2012 Jan 1;4:240-53. PMID: 22201868.

Airoldi C, Colombo L, Manzoni C, et al. Tetracycline prevents Aβ oligomer toxicity through an atypical supramolecular interaction. Org Biomol Chem. 2011 Jan 21;9(2):463-72. PMID: 21063627.

Griffin MO, Fricovsky E, Ceballos G, et al. Tetracyclines: a pleitropic family of compounds with promising therapeutic properties. Review of the literature. Am J Physiol Cell Physiol. 2010 Sep;299(3):C539-48. PMID: 20592239.

Hertweck M, Hiller R, Mueller MW. Inhibition of nuclear pre-mRNA splicing by antibiotics in vitro. Eur J Biochem. 2002 Jan;269(1):175-83. PMID: 11784311." Xn Not dangerous goods.

LKT T1677 Tetracycline 25 g 68.8 Polyketide; protein translation inhibitor, mammalian RNA splicing inhibitor, potential MMP inhibitor. [4S-(4α,4aα,5aα,6b,12aα)]-4-(Dimethylamino)-1,4,4a,-5,5a,6-11,12a-octahydro-3,6,10,12,12a-pentahydroxy-6-methyl-1,11-dioxo-2-naphthacenecarboxamide Deschlorobiomycin; Ambramycin; Liquamycin 60-54-8 ≥90% 444.43 C22H24N2O8 CC1(C2CC3C(C(=O)C(=C(C3(C(=O)C2=C(C4=C1C=CC=C4O)O)O)O)C(=O)N)N(C)C)O Ambient 4°C Soluble in methanol or ethanol (20 mg/mL). Slightly soluble in water (0.4 mg/mL). "Kennedy R, Alibhai M, Shakib K. Tetracycline: a cure all? Br J Oral Maxillofac Surg. 2014 Apr;52(4):382-3. PMID: 24613100.

Mahajan GB, Balachandran L. Antibacterial agents from actinomycetes - a review. Front Biosci (Elite Ed). 2012 Jan 1;4:240-53. PMID: 22201868.

Airoldi C, Colombo L, Manzoni C, et al. Tetracycline prevents Aβ oligomer toxicity through an atypical supramolecular interaction. Org Biomol Chem. 2011 Jan 21;9(2):463-72. PMID: 21063627.

Griffin MO, Fricovsky E, Ceballos G, et al. Tetracyclines: a pleitropic family of compounds with promising therapeutic properties. Review of the literature. Am J Physiol Cell Physiol. 2010 Sep;299(3):C539-48. PMID: 20592239.

Hertweck M, Hiller R, Mueller MW. Inhibition of nuclear pre-mRNA splicing by antibiotics in vitro. Eur J Biochem. 2002 Jan;269(1):175-83. PMID: 11784311." Xn Not dangerous goods.

LKT T1677 Tetracycline 100 g 198.5 Polyketide; protein translation inhibitor, mammalian RNA splicing inhibitor, potential MMP inhibitor. [4S-(4α,4aα,5aα,6b,12aα)]-4-(Dimethylamino)-1,4,4a,-5,5a,6-11,12a-octahydro-3,6,10,12,12a-pentahydroxy-6-methyl-1,11-dioxo-2-naphthacenecarboxamide Deschlorobiomycin; Ambramycin; Liquamycin 60-54-8 ≥90% 444.43 C22H24N2O8 CC1(C2CC3C(C(=O)C(=C(C3(C(=O)C2=C(C4=C1C=CC=C4O)O)O)O)C(=O)N)N(C)C)O Ambient 4°C Soluble in methanol or ethanol (20 mg/mL). Slightly soluble in water (0.4 mg/mL). "Kennedy R, Alibhai M, Shakib K. Tetracycline: a cure all? Br J Oral Maxillofac Surg. 2014 Apr;52(4):382-3. PMID: 24613100.

Mahajan GB, Balachandran L. Antibacterial agents from actinomycetes - a review. Front Biosci (Elite Ed). 2012 Jan 1;4:240-53. PMID: 22201868.

Airoldi C, Colombo L, Manzoni C, et al. Tetracycline prevents Aβ oligomer toxicity through an atypical supramolecular interaction. Org Biomol Chem. 2011 Jan 21;9(2):463-72. PMID: 21063627.

Griffin MO, Fricovsky E, Ceballos G, et al. Tetracyclines: a pleitropic family of compounds with promising therapeutic properties. Review of the literature. Am J Physiol Cell Physiol. 2010 Sep;299(3):C539-48. PMID: 20592239.

Hertweck M, Hiller R, Mueller MW. Inhibition of nuclear pre-mRNA splicing by antibiotics in vitro. Eur J Biochem. 2002 Jan;269(1):175-83. PMID: 11784311." Xn Not dangerous goods.

LKT L0250 Laminin Peptide SIKVAV 1 mg 81 Laminin-derived hexapeptide. ≥98% 2016.3 C82H148N31O26S Store in a cool, dry place. Ambient -20°C "Stevenson M, Hale AB, Hale SJ, et al. Incorporation of a laminin-derived peptide (SIKVAV) on polymer-modified adenovirus permits tumor-specific targeting via alpha6-integrins. Cancer Gene Ther. 2007 Apr;14(4):335-45. PMID: 17235355.

Freitas VM, Scheremeta B, Hoffman MP, et al. Laminin-1 and SIKVAV a laminin-1-derived peptide, regulate the morphology and protease activity of a human salivary gland adenoid cystic carcinoma cell line. Oral Oncol. 2004 May;40(5):483-9. PMID: 15006619.

Kibbey MC, Corcoran ML, Wahl LM, et al. Laminin SIKVAV peptide-induced angiogenesis in vivo is potentiated by neutrophils. J Cell Physiol. 1994 Jul;160(1):185-93. PMID: 7517404.

"

LKT L0250 Laminin Peptide SIKVAV 5 mg 288.8 Laminin-derived hexapeptide. ≥98% 2016.3 C82H148N31O26S Store in a cool, dry place. Ambient -20°C "Stevenson M, Hale AB, Hale SJ, et al. Incorporation of a laminin-derived peptide (SIKVAV) on polymer-modified adenovirus permits tumor-specific targeting via alpha6-integrins. Cancer Gene Ther. 2007 Apr;14(4):335-45. PMID: 17235355.

Freitas VM, Scheremeta B, Hoffman MP, et al. Laminin-1 and SIKVAV a laminin-1-derived peptide, regulate the morphology and protease activity of a human salivary gland adenoid cystic carcinoma cell line. Oral Oncol. 2004 May;40(5):483-9. PMID: 15006619.

Kibbey MC, Corcoran ML, Wahl LM, et al. Laminin SIKVAV peptide-induced angiogenesis in vivo is potentiated by neutrophils. J Cell Physiol. 1994 Jul;160(1):185-93. PMID: 7517404.

"

LKT L0251 Laminin Peptide CDPGYIGSR 1 mg 150.4 Laminin-derived nonapeptide. 110590-60-8 ≥98% 967.06 C40H62N12O14S Store in a cool, dry place. Ambient -20°C "Wenzel D, Koch M, Matthey M, et al. Identification of a novel vasoconstrictor peptide specific for the systemic circulation. Hypertension. 2012 Jun;59(6):1256-62. PMID: 22547445.

Sakamoto N, Iwahana M, Tanaka NG, et al. Inhibition of angiogenesis and tumor growth by a synthetic laminin peptide, CDPGYIGSR-NH2. Cancer Res. 1991 Feb 1;51(3):903-6. PMID: 1703042.

"

LKT L0251 Laminin Peptide CDPGYIGSR 5 mg 577.6 Laminin-derived nonapeptide. 110590-60-8 ≥98% 967.06 C40H62N12O14S Store in a cool, dry place. Ambient -20°C "Wenzel D, Koch M, Matthey M, et al. Identification of a novel vasoconstrictor peptide specific for the systemic circulation. Hypertension. 2012 Jun;59(6):1256-62. PMID: 22547445.

Sakamoto N, Iwahana M, Tanaka NG, et al. Inhibition of angiogenesis and tumor growth by a synthetic laminin peptide, CDPGYIGSR-NH2. Cancer Res. 1991 Feb 1;51(3):903-6. PMID: 1703042.

"

LKT T1676 L-Tetrahydropalmatine 100 mg 55 Alkaloid found in Corydalis and Stephania; D1/2 antagonist. 5,8,13,13a-Tetrahydro-2,3,9,10-tetramethoxy-6H- dibenzo[a,g]quinolizine (-)-Tetrahydropalmatine; Gindarine; Rotundine; Caseanine; 6H-Dibenzo[a,g]quinolizine, 5,8,13,13a-tetrahydro-2,3,9,10-tetramethoxy-, (13aS)-;13aa-Berbine, 2,3,9,10-tetramethoxy- (8CI); 6H-Dibenzo[a,g]quinolizine, 5,8,13,13a-tetrahydro-2,3,9,10-tetramethoxy-, (S)-; Cyclanoline, O,O-dimethyl-N-demethyl- (6CI); Gindarine (7CI); (-)-2,3,9,10-Tetramethoxyberbine; (-)-Corydalis B; (-)-Rotundine; (-)-S-Tetrahydropalmatine; (-)-Tetrahydropalmatine; (S)-Tetrahydropalmatine; Caseanine; Hyndarine; N-Demethyl-O,O'-dimethylcyclanoline; N-Demethyl-O,O'-dimethylsteponine; Palmatine, tetrahydro-, (-)-; Rotundine; Rotundine (Stephania), (-)-; l-Tetrahydropalmatine 483-14-7 ≥98% 355.43 C21H25NO4 COC1=C(C2=C(CC3C4=CC(=C(C=C4CCN3C2)OC)OC)C=C1)OC Protect from light. Store in a dry place. Ambient Ambient DMSO "Lee B, Sur B, Yeom M, et al. L-tetrahydropalmatine ameliorates development of anxiety and depression-related symptoms induced by single prolonged stress in rats. Biomol Ther (Seoul). 2014 May;22(3):213-22. PMID: 25009702.

Guo Z, Man Y, Wang X, et al. Levo-tetrahydropalmatine attenuates oxaliplatin-induced mechanical hyperalgesia in mice. Sci Rep. 2014 Jan 28;4:3905. PMID: 24469566.

Su HL, Zhu J, Chen YJ, et al. Roles of levo-tetrahydropalmatine in modulating methamphetamine reward behavior. Physiol Behav. 2013 Jun 13;118:195-200. PMID: 23711566.

Han Y, Zhang W, Tang Y, et al. l-Tetrahydropalmatine, an active component of Corydalis yanhusuo W.T. Wang, protects against myocardial ischaemia-reperfusion injury in rats. PLoS One. 2012;7(6):e38627. PMID: 22715398.

" Not dangerous goods.

LKT T1676 L-Tetrahydropalmatine 500 mg 198.1 Alkaloid found in Corydalis and Stephania; D1/2 antagonist. 5,8,13,13a-Tetrahydro-2,3,9,10-tetramethoxy-6H- dibenzo[a,g]quinolizine (-)-Tetrahydropalmatine; Gindarine; Rotundine; Caseanine; 6H-Dibenzo[a,g]quinolizine, 5,8,13,13a-tetrahydro-2,3,9,10-tetramethoxy-, (13aS)-;13aa-Berbine, 2,3,9,10-tetramethoxy- (8CI); 6H-Dibenzo[a,g]quinolizine, 5,8,13,13a-tetrahydro-2,3,9,10-tetramethoxy-, (S)-; Cyclanoline, O,O-dimethyl-N-demethyl- (6CI); Gindarine (7CI); (-)-2,3,9,10-Tetramethoxyberbine; (-)-Corydalis B; (-)-Rotundine; (-)-S-Tetrahydropalmatine; (-)-Tetrahydropalmatine; (S)-Tetrahydropalmatine; Caseanine; Hyndarine; N-Demethyl-O,O'-dimethylcyclanoline; N-Demethyl-O,O'-dimethylsteponine; Palmatine, tetrahydro-, (-)-; Rotundine; Rotundine (Stephania), (-)-; l-Tetrahydropalmatine 483-14-7 ≥98% 355.43 C21H25NO4 COC1=C(C2=C(CC3C4=CC(=C(C=C4CCN3C2)OC)OC)C=C1)OC Protect from light. Store in a dry place. Ambient Ambient DMSO "Lee B, Sur B, Yeom M, et al. L-tetrahydropalmatine ameliorates development of anxiety and depression-related symptoms induced by single prolonged stress in rats. Biomol Ther (Seoul). 2014 May;22(3):213-22. PMID: 25009702.

Guo Z, Man Y, Wang X, et al. Levo-tetrahydropalmatine attenuates oxaliplatin-induced mechanical hyperalgesia in mice. Sci Rep. 2014 Jan 28;4:3905. PMID: 24469566.

Su HL, Zhu J, Chen YJ, et al. Roles of levo-tetrahydropalmatine in modulating methamphetamine reward behavior. Physiol Behav. 2013 Jun 13;118:195-200. PMID: 23711566.

Han Y, Zhang W, Tang Y, et al. l-Tetrahydropalmatine, an active component of Corydalis yanhusuo W.T. Wang, protects against myocardial ischaemia-reperfusion injury in rats. PLoS One. 2012;7(6):e38627. PMID: 22715398.

" Not dangerous goods.

LKT L0254 Lansoprazole 250 mg 52.6 H+/K+ ATPase inhibitor. "1H-Benzimidazole, 2-(((3-methyl-4-(2,2,2-trifluoroethoxy)-2-

pyridinyl)methyl)sulfinyl)- 

" AG-1749; Agopton; Lansox; Lanzor; Limpidex. 103577-45-3 ≥98% 369.36 C16H14F3N3O2S CC1=C(C=CN=C1CS(=O)C2=NC3=CC=CC=C3N2)OCC(F)(F)F Ambient 4°C Insoluble in water. Soluble in methanol and DMF. "Koshio O, Tansho S, Ubagai T, et al. Suppression of phosphorylation of extracellular-signal-regulated kinase and p38 mitogen-activated protein kinase in polymorphonuclear leukocytes by the proton pump inhibitor lansoprazole. J Infect Chemother. 2010 Apr;16(2):100-6. PMID: 20094750.

Maity P, Bindu S, Choubey V, et al. Lansoprazole protects and heals gastric mucosa from non-steroidal anti-inflammatory drug (NSAID)-induced gastropathy by inhibiting mitochondrial as well as Fas-mediated death pathways with concurrent induction of mucosal cell renewal. J Biol Chem. 2008 May 23;283(21):14391-401. PMID: 18375387.

Hinoki A, Yoshimura K, Fujita K, et al. Suppression of proinflammatory cytokine production in macrophages by lansoprazole. Pediatr Surg Int. 2006 Nov;22(11):915-23. PMID: 16932910.

Shin JM, Cho YM, Sachs G. Chemistry of covalent inhibition of the gastric (H+, K+)-ATPase by proton pump inhibitors. J Am Chem Soc. 2004 Jun 30;126(25):7800-11. PMID: 15212527.

" Xi Not dangerous goods.

LKT L0254 Lansoprazole 1 g 147 H+/K+ ATPase inhibitor. "1H-Benzimidazole, 2-(((3-methyl-4-(2,2,2-trifluoroethoxy)-2-

pyridinyl)methyl)sulfinyl)- 

" AG-1749; Agopton; Lansox; Lanzor; Limpidex. 103577-45-3 ≥98% 369.36 C16H14F3N3O2S CC1=C(C=CN=C1CS(=O)C2=NC3=CC=CC=C3N2)OCC(F)(F)F Ambient 4°C Insoluble in water. Soluble in methanol and DMF. "Koshio O, Tansho S, Ubagai T, et al. Suppression of phosphorylation of extracellular-signal-regulated kinase and p38 mitogen-activated protein kinase in polymorphonuclear leukocytes by the proton pump inhibitor lansoprazole. J Infect Chemother. 2010 Apr;16(2):100-6. PMID: 20094750.

Maity P, Bindu S, Choubey V, et al. Lansoprazole protects and heals gastric mucosa from non-steroidal anti-inflammatory drug (NSAID)-induced gastropathy by inhibiting mitochondrial as well as Fas-mediated death pathways with concurrent induction of mucosal cell renewal. J Biol Chem. 2008 May 23;283(21):14391-401. PMID: 18375387.

Hinoki A, Yoshimura K, Fujita K, et al. Suppression of proinflammatory cytokine production in macrophages by lansoprazole. Pediatr Surg Int. 2006 Nov;22(11):915-23. PMID: 16932910.

Shin JM, Cho YM, Sachs G. Chemistry of covalent inhibition of the gastric (H+, K+)-ATPase by proton pump inhibitors. J Am Chem Soc. 2004 Jun 30;126(25):7800-11. PMID: 15212527.

" Xi Not dangerous goods.

LKT T1674 Terbutaline 1 g 65.6 β2-adrenergic agonist, potential ENaC activator. 5-[2-(tert-butylamino)-1-hydroxyethyl]benzene-1,3-diol 23031-25-6 ≥98% 225.28 C12H19NO3 CC(C)(C)NCC(C1=CC(=CC(=C1)O)O)O Ambient Ambient "Bohren Y, Tessier LH, Megat S, et al. Antidepressants suppress neuropathic pain by a peripheral β2-adrenoceptor mediated anti-TNFα mechanism. Neurobiol Dis. 2013 Dec;60:39-50. PMID: 23978467.

Freund-Michel VC, Birrell MA, Giembycz MA, et al. Beta(2)-agonists block tussive responses in guinea pigs via an atypical cAMP-dependent pathway. Eur Respir J. 2010 Mar;35(3):647-54. PMID: 19679606. 

Kontopoulos EV, Chandras C, Karalis K. Terbutaline inhibits corticotropin-releasing hormone (CRH) expression in human trophoblast cells. J Matern Fetal Neonatal Med. 2006 Nov;19(11):735-9. PMID: 17127497.

Planès C, Blot-Chabaud M, Matthay MA, et al. Hypoxia and beta 2-agonists regulate cell surface expression of the epithelial sodium channel in native alveolar epithelial cells. J Biol Chem. 2002 Dec 6;277(49):47318-24. PMID: 12372821.

Johnson M. Beta2-adrenoceptors: mechanisms of action of beta2-agonists. Paediatr Respir Rev. 2001 Mar;2(1):57-62. PMID: 16263481.

Lui PW, Hsing CH, Chu YC. Terbutaline inhalation suppresses *-induced coughing. Can J Anaesth. 1996 Dec;43(12):1216-9. PMID: 8955969.

Koseki N, Deguchi J, Yamashita A, et al. Establishment fo a novel experimental protocol for drug-induced seizure liability screening based on a locomotor activity assay in zebrafish. J Toxicol Sci. 2014 Aug;39(4):579-600. PMID: 25056783.

" Xn Not dangerous goods.

LKT T1674 Terbutaline 5 g 271.8 β2-adrenergic agonist, potential ENaC activator. 5-[2-(tert-butylamino)-1-hydroxyethyl]benzene-1,3-diol 23031-25-6 ≥98% 225.28 C12H19NO3 CC(C)(C)NCC(C1=CC(=CC(=C1)O)O)O Ambient Ambient "Bohren Y, Tessier LH, Megat S, et al. Antidepressants suppress neuropathic pain by a peripheral β2-adrenoceptor mediated anti-TNFα mechanism. Neurobiol Dis. 2013 Dec;60:39-50. PMID: 23978467.

Freund-Michel VC, Birrell MA, Giembycz MA, et al. Beta(2)-agonists block tussive responses in guinea pigs via an atypical cAMP-dependent pathway. Eur Respir J. 2010 Mar;35(3):647-54. PMID: 19679606. 

Kontopoulos EV, Chandras C, Karalis K. Terbutaline inhibits corticotropin-releasing hormone (CRH) expression in human trophoblast cells. J Matern Fetal Neonatal Med. 2006 Nov;19(11):735-9. PMID: 17127497.

Planès C, Blot-Chabaud M, Matthay MA, et al. Hypoxia and beta 2-agonists regulate cell surface expression of the epithelial sodium channel in native alveolar epithelial cells. J Biol Chem. 2002 Dec 6;277(49):47318-24. PMID: 12372821.

Johnson M. Beta2-adrenoceptors: mechanisms of action of beta2-agonists. Paediatr Respir Rev. 2001 Mar;2(1):57-62. PMID: 16263481.

Lui PW, Hsing CH, Chu YC. Terbutaline inhalation suppresses *-induced coughing. Can J Anaesth. 1996 Dec;43(12):1216-9. PMID: 8955969.

Koseki N, Deguchi J, Yamashita A, et al. Establishment fo a novel experimental protocol for drug-induced seizure liability screening based on a locomotor activity assay in zebrafish. J Toxicol Sci. 2014 Aug;39(4):579-600. PMID: 25056783.

" Xn Not dangerous goods.

LKT L0284 Lavendustin A 1 mg 215.7 Tyrosine kinase inhibitor. "5-Amino-[(N-2,5-dihydroxybenzyl)-N'-2-hydroxy- benzyl]salicylic Acid

" 5-[[(2,5-Dihydroxyphenyl)methyl][(2-hydroxyphenyl)- methyl]amino]-2-hydroxybenzoic acid 125697-92-9 ≥97% 381.38 C21H19NO6 C1=CC=C(C(=C1)CN(CC2=C(C=CC(=C2)O)O)C3=CC(=C(C=C3)O)C(=O)O)O Ambient -20°C Soluble in DMSO or ethanol, or acetic acid. "Rojas A, Wetherington J, Shaw R, et al. Activation of group I metabotropic glutamate receptors potentiates heteromeric kainate receptors. Mol Pharmacol. 2013 Jan;83(1):106-21. PMID: 23066089.

Kim HJ, Ahn HS, Choi BH, et al. Inhibition of Kv4.3 by genistein via a tyrosine phosphorylation-independent mechanism. Am J Physiol Cell Physiol. 2011 Mar;300(3):C567-75. PMID: 21148405.

Murakami K, Kanno H, Yamamoto I, et al. Lavendustin A enhances axon elongation in VHL gene-transfected neural stem cells. Neuroreport. 2004 Mar 22;15(4):611-4. PMID: 15094462.

" Xi Not dangerous goods.

LKT L0284 Lavendustin A 5 mg 759.8 Tyrosine kinase inhibitor. "5-Amino-[(N-2,5-dihydroxybenzyl)-N'-2-hydroxy- benzyl]salicylic Acid

" 5-[[(2,5-Dihydroxyphenyl)methyl][(2-hydroxyphenyl)- methyl]amino]-2-hydroxybenzoic acid 125697-92-9 ≥97% 381.38 C21H19NO6 C1=CC=C(C(=C1)CN(CC2=C(C=CC(=C2)O)O)C3=CC(=C(C=C3)O)C(=O)O)O Ambient -20°C Soluble in DMSO or ethanol, or acetic acid. "Rojas A, Wetherington J, Shaw R, et al. Activation of group I metabotropic glutamate receptors potentiates heteromeric kainate receptors. Mol Pharmacol. 2013 Jan;83(1):106-21. PMID: 23066089.

Kim HJ, Ahn HS, Choi BH, et al. Inhibition of Kv4.3 by genistein via a tyrosine phosphorylation-independent mechanism. Am J Physiol Cell Physiol. 2011 Mar;300(3):C567-75. PMID: 21148405.

Murakami K, Kanno H, Yamamoto I, et al. Lavendustin A enhances axon elongation in VHL gene-transfected neural stem cells. Neuroreport. 2004 Mar 22;15(4):611-4. PMID: 15094462.

" Xi Not dangerous goods.

LKT L0349 Lamotrigine 25 mg 84.3 R-type Ca2+ and voltage-gated Na+ channel blocker. 6-(2,3-Dichlorophenyl)-1,2,4-triazine-3,5-diamine 84057-84-1 ≥98% 255.01 C9H7Cl2N5 C1=CC(=C(C(=C1)Cl)Cl)C2=C(N=C(N=N2)N)N In DMSO at +4 for 2 weeks at -80 for 6 months. Ambient Ambient Warm DMSO to 20 mg/mL, warm ethanol to 25 mM, methanol "Himmerich H, Bartsch S, Hamer H, et al. Impact of mood stabilizers and antiepileptic drugs on cytokine production in-vitro. J Psychiatr Res. 2013 Nov;47(11):1751-9. PMID: 23978396.

Dibué M, Kamp MA, Alpdogan S, et al. Cav 2.3 (R-type) calcium channels are critical for mediating anticonvulsive and neuroprotective properties of lamotrigine in vivo. Epilepsia. 2013 Sep;54(9):1542-50. PMID: 23772876.

Munro G, Erichsen HK, Mirza NR. Pharmacological comparison of anticonvulsant drugs in animal models of persistent pain and anxiety. Neuropharmacology. 2007 Oct;53(5):609-18. PMID: 17714743.

Kaster MP, Raupp I, Binfaré RW, et al. Antidepressant-like effect of lamotrigine in the mouse forced swimming test: evidence for the involvement of the noradrenergic system. Eur J Pharmacol. 2007 Jun 22;565(1-3):119-24. PMID: 17433291.

Leach MJ, Marden CM, Miller AA. Pharmacological studies on lamotrigine, a novel potential antiepileptic drug: II. Neurochemical studies on the mechanism of action. Epilepsia. 1986 Sep-Oct;27(5):490-7. PMID: 3757936.

Ookubo M, Kanai H, Aoki H, Yamada N. Antidepressants and mood stabilizers effects on histone deacetylase expression in C57BL/6 mice: brain region specific changes. J Psychiatr Res. 2013 Sep;47(9):1204-1214. PMID: 23777937.

" T "UN number: 2811     Class: 6.1     Packing Group: III

Proper shipping name: Toxic solid, organic, n.o.s. (Lamotrigine)"

LKT L0349 Lamotrigine 100 mg 271.8 R-type Ca2+ and voltage-gated Na+ channel blocker. 6-(2,3-Dichlorophenyl)-1,2,4-triazine-3,5-diamine 84057-84-1 ≥98% 255.01 C9H7Cl2N5 C1=CC(=C(C(=C1)Cl)Cl)C2=C(N=C(N=N2)N)N In DMSO at +4 for 2 weeks at -80 for 6 months. Ambient Ambient Warm DMSO to 20 mg/mL, warm ethanol to 25 mM, methanol "Himmerich H, Bartsch S, Hamer H, et al. Impact of mood stabilizers and antiepileptic drugs on cytokine production in-vitro. J Psychiatr Res. 2013 Nov;47(11):1751-9. PMID: 23978396.

Dibué M, Kamp MA, Alpdogan S, et al. Cav 2.3 (R-type) calcium channels are critical for mediating anticonvulsive and neuroprotective properties of lamotrigine in vivo. Epilepsia. 2013 Sep;54(9):1542-50. PMID: 23772876.

Munro G, Erichsen HK, Mirza NR. Pharmacological comparison of anticonvulsant drugs in animal models of persistent pain and anxiety. Neuropharmacology. 2007 Oct;53(5):609-18. PMID: 17714743.

Kaster MP, Raupp I, Binfaré RW, et al. Antidepressant-like effect of lamotrigine in the mouse forced swimming test: evidence for the involvement of the noradrenergic system. Eur J Pharmacol. 2007 Jun 22;565(1-3):119-24. PMID: 17433291.

Leach MJ, Marden CM, Miller AA. Pharmacological studies on lamotrigine, a novel potential antiepileptic drug: II. Neurochemical studies on the mechanism of action. Epilepsia. 1986 Sep-Oct;27(5):490-7. PMID: 3757936.

Ookubo M, Kanai H, Aoki H, Yamada N. Antidepressants and mood stabilizers effects on histone deacetylase expression in C57BL/6 mice: brain region specific changes. J Psychiatr Res. 2013 Sep;47(9):1204-1214. PMID: 23777937.

" T "UN number: 2811     Class: 6.1     Packing Group: III

Proper shipping name: Toxic solid, organic, n.o.s. (Lamotrigine)"

LKT L0349 Lamotrigine 500 mg 843.9 R-type Ca2+ and voltage-gated Na+ channel blocker. 6-(2,3-Dichlorophenyl)-1,2,4-triazine-3,5-diamine 84057-84-1 ≥98% 255.01 C9H7Cl2N5 C1=CC(=C(C(=C1)Cl)Cl)C2=C(N=C(N=N2)N)N In DMSO at +4 for 2 weeks at -80 for 6 months. Ambient Ambient Warm DMSO to 20 mg/mL, warm ethanol to 25 mM, methanol "Himmerich H, Bartsch S, Hamer H, et al. Impact of mood stabilizers and antiepileptic drugs on cytokine production in-vitro. J Psychiatr Res. 2013 Nov;47(11):1751-9. PMID: 23978396.

Dibué M, Kamp MA, Alpdogan S, et al. Cav 2.3 (R-type) calcium channels are critical for mediating anticonvulsive and neuroprotective properties of lamotrigine in vivo. Epilepsia. 2013 Sep;54(9):1542-50. PMID: 23772876.

Munro G, Erichsen HK, Mirza NR. Pharmacological comparison of anticonvulsant drugs in animal models of persistent pain and anxiety. Neuropharmacology. 2007 Oct;53(5):609-18. PMID: 17714743.

Kaster MP, Raupp I, Binfaré RW, et al. Antidepressant-like effect of lamotrigine in the mouse forced swimming test: evidence for the involvement of the noradrenergic system. Eur J Pharmacol. 2007 Jun 22;565(1-3):119-24. PMID: 17433291.

Leach MJ, Marden CM, Miller AA. Pharmacological studies on lamotrigine, a novel potential antiepileptic drug: II. Neurochemical studies on the mechanism of action. Epilepsia. 1986 Sep-Oct;27(5):490-7. PMID: 3757936.

Ookubo M, Kanai H, Aoki H, Yamada N. Antidepressants and mood stabilizers effects on histone deacetylase expression in C57BL/6 mice: brain region specific changes. J Psychiatr Res. 2013 Sep;47(9):1204-1214. PMID: 23777937.

" T "UN number: 2811     Class: 6.1     Packing Group: III

Proper shipping name: Toxic solid, organic, n.o.s. (Lamotrigine)"

LKT T1673 Terlipressin Acetate 1 mg 93.8 Synthetic peptide, vasopressin analog; AVPR1 agonist. 14636-12-5 ≥95% 1227.37 C52H74N16O15S2 C1CC(N(C1)C(=O)C2CSSCC(C(=O)NC(C(=O)NC(C(=O)NC(C(=O)NC(C(=O)N2)CC(=O)N)CCC(=O)N)CC3=CC=CC=C3)CC4=CC=C(C=C4)O)NC(=O)CNC(=O)CNC(=O)CN)C(=O)NC(CCCCN)C(=O)NCC(=O)N Ambient -20°C "Lange M, Van Aken H, Westphal M, et al. Role of vasopressinergic V1 receptor agonists in the treatment of perioperative catecholamine-refractory arterial hypotension. Best Pract Res Clin Anaesthesiol. 2008 Jun;22(2):369-81. PMID: 18683482.

Betrosian AP, Agarwal B, Douzinas EE. Acute renal dysfunction in liver diseases. World J Gastroenterol. 2007 Nov 14;13(42):5552-9. PMID: 17948928.

Nowak L, Królczyk G, Sobocki J, et al. Gastric stimulation is effective in reversing vasopressin induced gastroparesis. Folia Med Cracov. 2004;45(1-2):71-9. PMID: 16276827.

Heinemann A, Stauber RE. Effect of terlipressin on in vitro vascular hyporeactivity of portal hypertensive rats. J Hepatol. 1996 Jun;24(6):739-46. PMID: 8835750.

" Not dangerous goods.

LKT T1673 Terlipressin Acetate 5 mg 328.1 Synthetic peptide, vasopressin analog; AVPR1 agonist. 14636-12-5 ≥95% 1227.37 C52H74N16O15S2 C1CC(N(C1)C(=O)C2CSSCC(C(=O)NC(C(=O)NC(C(=O)NC(C(=O)NC(C(=O)N2)CC(=O)N)CCC(=O)N)CC3=CC=CC=C3)CC4=CC=C(C=C4)O)NC(=O)CNC(=O)CNC(=O)CN)C(=O)NC(CCCCN)C(=O)NCC(=O)N Ambient -20°C "Lange M, Van Aken H, Westphal M, et al. Role of vasopressinergic V1 receptor agonists in the treatment of perioperative catecholamine-refractory arterial hypotension. Best Pract Res Clin Anaesthesiol. 2008 Jun;22(2):369-81. PMID: 18683482.

Betrosian AP, Agarwal B, Douzinas EE. Acute renal dysfunction in liver diseases. World J Gastroenterol. 2007 Nov 14;13(42):5552-9. PMID: 17948928.

Nowak L, Królczyk G, Sobocki J, et al. Gastric stimulation is effective in reversing vasopressin induced gastroparesis. Folia Med Cracov. 2004;45(1-2):71-9. PMID: 16276827.

Heinemann A, Stauber RE. Effect of terlipressin on in vitro vascular hyporeactivity of portal hypertensive rats. J Hepatol. 1996 Jun;24(6):739-46. PMID: 8835750.

" Not dangerous goods.

LKT L0360 Lapatinib Ditosylate Monohydrate 10 mg 122.3 EGFR inhibitor. 388082-78-8 ≥98% 925.46 C26H26ClFN4O4S 2C7H8O3S H2O CC1=CC=C(C=C1)S(=O)(=O)O.CC1=CC=C(C=C1)S(=O)(=O)O.CS(=O)(=O)CCNCC1=CC=C(O1)C2=CC3=C(C=C2)N=CN=C3NC4=CC(=C(C=C4)OCC5=CC(=CC=C5)F)Cl Ambient 4°C Slightly in DMSO "Janni W, Sarosiek T, Karaszewska B, et al. A phase II, randomized, multicenter study evaluating the combination of lapatinib and vinorelbine in women with ErbB2 overexpressing metastatic breast cancer. Breast Cancer Res Treat. 2014 Jan 9. [Epub ahead of print]. PMID: 24402830.

Kostyal D, Welt RS, Danko J, et al. Trastuzumab and lapatinib modulation of HER2 tyrosine/threonine phosphorylation and cell signaling. Med Oncol. 2012 Sep;29(3):1486-94. PMID: 21769502.

Kim HP, Yoon YK, Kim JW, et al. Lapatinib, a dual EGFR and HER2 tyrosine kinase inhibitor, downregulates thymidylate synthase by inhibiting the nuclear translocation of EGFR and HER2. PLoS One. 2009 Jun 16;4(6):e5933. PMID: 19529774.

" Not dangerous goods.

LKT L0360 Lapatinib Ditosylate Monohydrate 25 mg 203.8 EGFR inhibitor. 388082-78-8 ≥98% 925.46 C26H26ClFN4O4S 2C7H8O3S H2O CC1=CC=C(C=C1)S(=O)(=O)O.CC1=CC=C(C=C1)S(=O)(=O)O.CS(=O)(=O)CCNCC1=CC=C(O1)C2=CC3=C(C=C2)N=CN=C3NC4=CC(=C(C=C4)OCC5=CC(=CC=C5)F)Cl Ambient 4°C Slightly in DMSO "Janni W, Sarosiek T, Karaszewska B, et al. A phase II, randomized, multicenter study evaluating the combination of lapatinib and vinorelbine in women with ErbB2 overexpressing metastatic breast cancer. Breast Cancer Res Treat. 2014 Jan 9. [Epub ahead of print]. PMID: 24402830.

Kostyal D, Welt RS, Danko J, et al. Trastuzumab and lapatinib modulation of HER2 tyrosine/threonine phosphorylation and cell signaling. Med Oncol. 2012 Sep;29(3):1486-94. PMID: 21769502.

Kim HP, Yoon YK, Kim JW, et al. Lapatinib, a dual EGFR and HER2 tyrosine kinase inhibitor, downregulates thymidylate synthase by inhibiting the nuclear translocation of EGFR and HER2. PLoS One. 2009 Jun 16;4(6):e5933. PMID: 19529774.

" Not dangerous goods.

LKT L0360 Lapatinib Ditosylate Monohydrate 100 mg 611.5 EGFR inhibitor. 388082-78-8 ≥98% 925.46 C26H26ClFN4O4S 2C7H8O3S H2O CC1=CC=C(C=C1)S(=O)(=O)O.CC1=CC=C(C=C1)S(=O)(=O)O.CS(=O)(=O)CCNCC1=CC=C(O1)C2=CC3=C(C=C2)N=CN=C3NC4=CC(=C(C=C4)OCC5=CC(=CC=C5)F)Cl Ambient 4°C Slightly in DMSO "Janni W, Sarosiek T, Karaszewska B, et al. A phase II, randomized, multicenter study evaluating the combination of lapatinib and vinorelbine in women with ErbB2 overexpressing metastatic breast cancer. Breast Cancer Res Treat. 2014 Jan 9. [Epub ahead of print]. PMID: 24402830.

Kostyal D, Welt RS, Danko J, et al. Trastuzumab and lapatinib modulation of HER2 tyrosine/threonine phosphorylation and cell signaling. Med Oncol. 2012 Sep;29(3):1486-94. PMID: 21769502.

Kim HP, Yoon YK, Kim JW, et al. Lapatinib, a dual EGFR and HER2 tyrosine kinase inhibitor, downregulates thymidylate synthase by inhibiting the nuclear translocation of EGFR and HER2. PLoS One. 2009 Jun 16;4(6):e5933. PMID: 19529774.

" Not dangerous goods.

LKT T1672 Terbinafine Hydrochloride 1 g 115.5 Allylamine; squalene oxidase and KSR1 inhibitor. N-[(2E)-6,6-Dimethyl-2-hepten-4-ynyl]-N-methyl-1- naphthalenemethanamine hydrochloride Lamisil 78628-80-5 ≥98% 327.9 C21H25N HCl CC(C)(C)C#CC=CCN(C)CC1=CC=CC2=CC=CC=C21.Cl Ambient 4°C Soluble in methanol, methylene chloride or ethanol. "Li B, Lu L, Zhong M, et al. Terbinafine inhibits KSR1 and suppresses Raf-MEK-ERK signaling in oral squamous cell carcinoma cells. Neoplasma. 2013;60(4):406-12. PMID: 23581412.

Nowosielski M, Hoffmann M, Wyrwicz LS, et al. Detailed mechanism of squalene epoxidase inhibition by terbinafine. J Chem Inf Model. 2011 Feb 28;51(2):455-62. PMID: 21229992.

Revankar SG, Nailor MD, Sobel JD. Use of terbinafine in rare and refractory mycoses. Future Microbiol. 2008 Feb;3(1):9-17. PMID: 18230029.

" Xi, N Not dangerous goods.

LKT T1672 Terbinafine Hydrochloride 5 g 462.1 Allylamine; squalene oxidase and KSR1 inhibitor. N-[(2E)-6,6-Dimethyl-2-hepten-4-ynyl]-N-methyl-1- naphthalenemethanamine hydrochloride Lamisil 78628-80-5 ≥98% 327.9 C21H25N HCl CC(C)(C)C#CC=CCN(C)CC1=CC=CC2=CC=CC=C21.Cl Ambient 4°C Soluble in methanol, methylene chloride or ethanol. "Li B, Lu L, Zhong M, et al. Terbinafine inhibits KSR1 and suppresses Raf-MEK-ERK signaling in oral squamous cell carcinoma cells. Neoplasma. 2013;60(4):406-12. PMID: 23581412.

Nowosielski M, Hoffmann M, Wyrwicz LS, et al. Detailed mechanism of squalene epoxidase inhibition by terbinafine. J Chem Inf Model. 2011 Feb 28;51(2):455-62. PMID: 21229992.

Revankar SG, Nailor MD, Sobel JD. Use of terbinafine in rare and refractory mycoses. Future Microbiol. 2008 Feb;3(1):9-17. PMID: 18230029.

" Xi, N Not dangerous goods.

LKT T1672 Terbinafine Hydrochloride 10 g 808.5 Allylamine; squalene oxidase and KSR1 inhibitor. N-[(2E)-6,6-Dimethyl-2-hepten-4-ynyl]-N-methyl-1- naphthalenemethanamine hydrochloride Lamisil 78628-80-5 ≥98% 327.9 C21H25N HCl CC(C)(C)C#CC=CCN(C)CC1=CC=CC2=CC=CC=C21.Cl Ambient 4°C Soluble in methanol, methylene chloride or ethanol. "Li B, Lu L, Zhong M, et al. Terbinafine inhibits KSR1 and suppresses Raf-MEK-ERK signaling in oral squamous cell carcinoma cells. Neoplasma. 2013;60(4):406-12. PMID: 23581412.

Nowosielski M, Hoffmann M, Wyrwicz LS, et al. Detailed mechanism of squalene epoxidase inhibition by terbinafine. J Chem Inf Model. 2011 Feb 28;51(2):455-62. PMID: 21229992.

Revankar SG, Nailor MD, Sobel JD. Use of terbinafine in rare and refractory mycoses. Future Microbiol. 2008 Feb;3(1):9-17. PMID: 18230029.

" Xi, N Not dangerous goods.

LKT L1628 Ac-LEHD-pNa 1 mg 78 Caspase 9 substrate. Chromogenic caspase-4, 5, 9 substrate ≥95% 674.7 C29H38N8O11 Ambient -20°C "Yi HS, Pan C, Pan C, et al. BmICE-2 is a novel pro-apoptotic caspase involved in apoptosis in the silkworm, Bombyx mori. Biochem Biophys Res Commun. 2014 Jan 31. pii: S0006-291X(14)00174-0. [Epub ahead of print]. PMID: 24491540.

Yun CY, Liu S, Lim SF, et al. Specific inhibition of caspase-8 and -9 in CHO cells enhances cell viability in batch and fed-batch cultures. Metab Eng. 2007 Sep-Nov;9(5-6):406-18. PMID: 17658284.

" Not dangerous goods.

LKT L1628 Ac-LEHD-pNa 2 mg 132 Caspase 9 substrate. Chromogenic caspase-4, 5, 9 substrate ≥95% 674.7 C29H38N8O11 Ambient -20°C "Yi HS, Pan C, Pan C, et al. BmICE-2 is a novel pro-apoptotic caspase involved in apoptosis in the silkworm, Bombyx mori. Biochem Biophys Res Commun. 2014 Jan 31. pii: S0006-291X(14)00174-0. [Epub ahead of print]. PMID: 24491540.

Yun CY, Liu S, Lim SF, et al. Specific inhibition of caspase-8 and -9 in CHO cells enhances cell viability in batch and fed-batch cultures. Metab Eng. 2007 Sep-Nov;9(5-6):406-18. PMID: 17658284.

" Not dangerous goods.

LKT L1628 Ac-LEHD-pNa 5 mg 231.1 Caspase 9 substrate. Chromogenic caspase-4, 5, 9 substrate ≥95% 674.7 C29H38N8O11 Ambient -20°C "Yi HS, Pan C, Pan C, et al. BmICE-2 is a novel pro-apoptotic caspase involved in apoptosis in the silkworm, Bombyx mori. Biochem Biophys Res Commun. 2014 Jan 31. pii: S0006-291X(14)00174-0. [Epub ahead of print]. PMID: 24491540.

Yun CY, Liu S, Lim SF, et al. Specific inhibition of caspase-8 and -9 in CHO cells enhances cell viability in batch and fed-batch cultures. Metab Eng. 2007 Sep-Nov;9(5-6):406-18. PMID: 17658284.

" Not dangerous goods.

LKT L1660 Leptin (22-56), human 1 mg 705.8 Endogenous peptide fragment, involved in feeding behavior and energy homeostasis; leptin agonist. OBGRP(22-56), human ≥98% 3950.6 C171H298N50O56 Ambient -20°C "Comninos AN, Jayasena CN, Dhillo WS. The relationship between gut and adipose hormones, and reproduction. Hum Reprod Update. 2014 Mar-Apr;20(2):153-74. PMID: 24173881.

Greco SJ, Bryan KJ, Sarkar S, et al. Leptin reduces pathology and improves memory in a transgenic mouse model of Alzheimer's disease. J Alzheimers Dis. 2010;19(4):1155-67. PMID: 20308782.

Zhang W, Telemaque S, Augustyniak RA, et al. Adenovirus-mediated leptin expression normalises hypertension associated with diet-induced obesity. J Neuroendocrinol. 2010 Mar;22(3):175-80. PMID: 20059648.

Taleb S, Herbin O, Ait-Oufella H, et al. Defective leptin/leptin receptor signaling improves regulatory T cell immune response and protects mice from atherosclerosis. Arterioscler Thromb Vasc Biol. 2007 Dec;27(12):2691-8. PMID: 17690315.

Martin A, David V, Malaval L, et al. Opposite effects of leptin on bone metabolism: a dose-dependent balance related to energy intake and insulin-like growth factor-I pathway. Endocrinology. 2007 Jul;148(7):3419-25. PMID: 17431002.

Moynihan AT, Hehir MP, Glavey SV, et al. Inhibitory effect of leptin on human uterine contractility in vitro. Am J Obstet Gynecol. 2006 Aug;195(2):504-9. PMID: 16647683.

Mantzoros CS. The role of leptin in human obesity and disease: a review of current evidence. Ann Intern Med. 1999 Apr 20;130(8):671-80. PMID: 10215564.

"

LKT L1661 Leptin (116-130), mouse 0.5 mg 180 Endogenous peptide fragment, involved in feeding behavior and energy homeostasis; leptin agonist. ≥95% 1560.74 C64H107N18O25S1 Ambient -20°C "Rozhavskaya-Arena M, Lee DW, Leinung MC, et al. Design of a synthetic leptin agonist: effects on energy balance, glucose homeostasis, and thermoregulation. Endocrinology. 2000 Jul;141(7):2501-7. PMID: 10875251.

Malendowicz LK, Tortorella C, Nowak KW, et al. Leptin prolonged administration inhibits the growth and glucocorticoid secretion of rat adrenal cortex. Endocr Res. 2000 May;26(2):141-52. PMID: 10921444.

Tena-Sempere M, Pinilla L, González LC, et al. In vitro pituitary and testicular effects of the leptin-related synthetic peptide leptin(116-130) amide involve actions both similar to and distinct from those of the native leptin molecule in the adult rat. Eur J Endocrinol. 2000 Apr;142(4):406-10. PMID: 10754484.

" Not dangerous goods.

LKT L1661 Leptin (116-130), mouse 1 mg 306.1 Endogenous peptide fragment, involved in feeding behavior and energy homeostasis; leptin agonist. ≥95% 1560.74 C64H107N18O25S1 Ambient -20°C "Rozhavskaya-Arena M, Lee DW, Leinung MC, et al. Design of a synthetic leptin agonist: effects on energy balance, glucose homeostasis, and thermoregulation. Endocrinology. 2000 Jul;141(7):2501-7. PMID: 10875251.

Malendowicz LK, Tortorella C, Nowak KW, et al. Leptin prolonged administration inhibits the growth and glucocorticoid secretion of rat adrenal cortex. Endocr Res. 2000 May;26(2):141-52. PMID: 10921444.

Tena-Sempere M, Pinilla L, González LC, et al. In vitro pituitary and testicular effects of the leptin-related synthetic peptide leptin(116-130) amide involve actions both similar to and distinct from those of the native leptin molecule in the adult rat. Eur J Endocrinol. 2000 Apr;142(4):406-10. PMID: 10754484.

" Not dangerous goods.

LKT L1661 Leptin (116-130), mouse 2.5 mg 540 Endogenous peptide fragment, involved in feeding behavior and energy homeostasis; leptin agonist. ≥95% 1560.74 C64H107N18O25S1 Ambient -20°C "Rozhavskaya-Arena M, Lee DW, Leinung MC, et al. Design of a synthetic leptin agonist: effects on energy balance, glucose homeostasis, and thermoregulation. Endocrinology. 2000 Jul;141(7):2501-7. PMID: 10875251.

Malendowicz LK, Tortorella C, Nowak KW, et al. Leptin prolonged administration inhibits the growth and glucocorticoid secretion of rat adrenal cortex. Endocr Res. 2000 May;26(2):141-52. PMID: 10921444.

Tena-Sempere M, Pinilla L, González LC, et al. In vitro pituitary and testicular effects of the leptin-related synthetic peptide leptin(116-130) amide involve actions both similar to and distinct from those of the native leptin molecule in the adult rat. Eur J Endocrinol. 2000 Apr;142(4):406-10. PMID: 10754484.

" Not dangerous goods.

LKT L1682 Levamisole Hydrochloride 5 g 40.7 Imidazothiazole; alkaline phosphatase inhibitor, potential nAChR agonist. Imidazo(2,1-b)thiazole,2,3,5,6-tetrahydro-6-phenyl-, monohydrochloride, (-)- (8CI) Tetramisole hydrochloride; Citarin L; Ergamisol; Spartakon 16595-80-5 ≥98% 240.76 C11H12N2S HCl C1CSC2=NC(CN21)C3=CC=CC=C3.Cl Sensitive to light. Ambient Ambient Soluble in water. "Ramanadham M, Nageshwari B. Anti-proliferative effect of levamisole on human myeloma cell lines in vitro. J Immunotoxicol. 2010 Oct-Dec;7(4):327-32. PMID: 20860474.

Friis T, Engel AM, Klein BM, et al. Levamisole inhibits angiogenesis in vitro and tumor growth in vivo. Angiogenesis. 2005;8(1):25-34. PMID: 16132615.

Zinser EW, Wolf ML, Alexander-Bowman SJ, et al. Anthelmintic paraherquamides are cholinergic antagonists in gastrointestinal nematodes and mammals. J Vet Pharmacol Ther. 2002 Aug;25(4):241-50. PMID: 12213111.

Van Belle H. Alkaline phosphatase. I. Kinetics and inhibition by levamisole of purified isoenzymes from humans. Clin Chem. 1976 Jul;22(7):972-6. PMID: 6169.

" T "UN number: 2811     Class:  6.1     Packing group:  III

Proper shipping name:  Toxic solids, organic, n.o.s. (Levamisole hydrochloride)

Marine pollutant:  No     Poison inhalation hazard:  No"

LKT L1682 Levamisole Hydrochloride 10 g 67.9 Imidazothiazole; alkaline phosphatase inhibitor, potential nAChR agonist. Imidazo(2,1-b)thiazole,2,3,5,6-tetrahydro-6-phenyl-, monohydrochloride, (-)- (8CI) Tetramisole hydrochloride; Citarin L; Ergamisol; Spartakon 16595-80-5 ≥98% 240.76 C11H12N2S HCl C1CSC2=NC(CN21)C3=CC=CC=C3.Cl Sensitive to light. Ambient Ambient Soluble in water. "Ramanadham M, Nageshwari B. Anti-proliferative effect of levamisole on human myeloma cell lines in vitro. J Immunotoxicol. 2010 Oct-Dec;7(4):327-32. PMID: 20860474.

Friis T, Engel AM, Klein BM, et al. Levamisole inhibits angiogenesis in vitro and tumor growth in vivo. Angiogenesis. 2005;8(1):25-34. PMID: 16132615.

Zinser EW, Wolf ML, Alexander-Bowman SJ, et al. Anthelmintic paraherquamides are cholinergic antagonists in gastrointestinal nematodes and mammals. J Vet Pharmacol Ther. 2002 Aug;25(4):241-50. PMID: 12213111.

Van Belle H. Alkaline phosphatase. I. Kinetics and inhibition by levamisole of purified isoenzymes from humans. Clin Chem. 1976 Jul;22(7):972-6. PMID: 6169.

" T "UN number: 2811     Class:  6.1     Packing group:  III

Proper shipping name:  Toxic solids, organic, n.o.s. (Levamisole hydrochloride)

Marine pollutant:  No     Poison inhalation hazard:  No"

LKT T1670 Terazosin Hydrochloride Dihydrate 50 mg 67.9 Quinazoline; α1-adrenergic antagonist. "1-(4-Amino-6,7-dimethoxy-2-quinazolinyl)-4-(tetrahydro-2-

furoyl)piperazine monohydrochloride dihydrate" Heitrin; Hytracin; Hytrin; Hytrinex; Itrin; Urodie; Vasocard 70024-40-7 ≥98% 459.93 C19H25N5O4 HCl 2H2O COC1=C(C=C2C(=C1)C(=NC(=N2)N3CCN(CC3)C(=O)C4CCCO4)N)OC.O.O.Cl Ambient Ambient Soluble in water. "Oelke M, Gericke A, Michel MC. Cardiovascular and ocular safety of α1-adrenoceptor antagonists in the treatment of male lower urinary tract symptoms. Expert Opin Drug Saf. 2014 Sep;13(9):1187-97. PMID: 25073735.

Papadopoulos G, Vlachodimitropoulos D, Kyroudi A, et al. Terazosin treatment induces caspase-3 expression in the rat ventral prostate. J Clin Med Res. 2013 Apr;5(2):127-31. PMID: 23518907.

Tahmatzopoulos A, Rowland RG, Kyprianou N. The role of alpha-blockers in the management of prostate cancer. Expert Opin Pharmacother. 2004 Jun;5(6):1279-85. PMID: 15163273.

Tomoda F, Takata M, Yoshida K, et al. Hemodynamic and endocrinological effects of a new selective alpha 1-blocking agent, terazosin, in patients with essential hypertension. Results of long-term treatment. Am J Hypertens. 1989 Nov;2(11 Pt 1):834-9. PMID: 2574044.

" Not dangerous goods.

LKT T1670 Terazosin Hydrochloride Dihydrate 250 mg 269.1 Quinazoline; α1-adrenergic antagonist. "1-(4-Amino-6,7-dimethoxy-2-quinazolinyl)-4-(tetrahydro-2-

furoyl)piperazine monohydrochloride dihydrate" Heitrin; Hytracin; Hytrin; Hytrinex; Itrin; Urodie; Vasocard 70024-40-7 ≥98% 459.93 C19H25N5O4 HCl 2H2O COC1=C(C=C2C(=C1)C(=NC(=N2)N3CCN(CC3)C(=O)C4CCCO4)N)OC.O.O.Cl Ambient Ambient Soluble in water. "Oelke M, Gericke A, Michel MC. Cardiovascular and ocular safety of α1-adrenoceptor antagonists in the treatment of male lower urinary tract symptoms. Expert Opin Drug Saf. 2014 Sep;13(9):1187-97. PMID: 25073735.

Papadopoulos G, Vlachodimitropoulos D, Kyroudi A, et al. Terazosin treatment induces caspase-3 expression in the rat ventral prostate. J Clin Med Res. 2013 Apr;5(2):127-31. PMID: 23518907.

Tahmatzopoulos A, Rowland RG, Kyprianou N. The role of alpha-blockers in the management of prostate cancer. Expert Opin Pharmacother. 2004 Jun;5(6):1279-85. PMID: 15163273.

Tomoda F, Takata M, Yoshida K, et al. Hemodynamic and endocrinological effects of a new selective alpha 1-blocking agent, terazosin, in patients with essential hypertension. Results of long-term treatment. Am J Hypertens. 1989 Nov;2(11 Pt 1):834-9. PMID: 2574044.

" Not dangerous goods.

LKT T1670 Terazosin Hydrochloride Dihydrate 1 g 788.2 Quinazoline; α1-adrenergic antagonist. "1-(4-Amino-6,7-dimethoxy-2-quinazolinyl)-4-(tetrahydro-2-

furoyl)piperazine monohydrochloride dihydrate" Heitrin; Hytracin; Hytrin; Hytrinex; Itrin; Urodie; Vasocard 70024-40-7 ≥98% 459.93 C19H25N5O4 HCl 2H2O COC1=C(C=C2C(=C1)C(=NC(=N2)N3CCN(CC3)C(=O)C4CCCO4)N)OC.O.O.Cl Ambient Ambient Soluble in water. "Oelke M, Gericke A, Michel MC. Cardiovascular and ocular safety of α1-adrenoceptor antagonists in the treatment of male lower urinary tract symptoms. Expert Opin Drug Saf. 2014 Sep;13(9):1187-97. PMID: 25073735.

Papadopoulos G, Vlachodimitropoulos D, Kyroudi A, et al. Terazosin treatment induces caspase-3 expression in the rat ventral prostate. J Clin Med Res. 2013 Apr;5(2):127-31. PMID: 23518907.

Tahmatzopoulos A, Rowland RG, Kyprianou N. The role of alpha-blockers in the management of prostate cancer. Expert Opin Pharmacother. 2004 Jun;5(6):1279-85. PMID: 15163273.

Tomoda F, Takata M, Yoshida K, et al. Hemodynamic and endocrinological effects of a new selective alpha 1-blocking agent, terazosin, in patients with essential hypertension. Results of long-term treatment. Am J Hypertens. 1989 Nov;2(11 Pt 1):834-9. PMID: 2574044.

" Not dangerous goods.

LKT L1684 Levonorgestrel 100 mg 60.4 Synthetic progestogen; contraceptive. 17-Ethynyl-18-methyl-19-nortestosterone D(−) Norgestrel; Microlut; Microval; Norgeston; Norlevo; Norplant 797-63-7 ≥98% 312.45 C21H28O2 CCC12CCC3C(C1CCC2(C#C)O)CCC4=CC(=O)CCC34 Ambient Ambient Insoluble in water. Slightly soluble in alcohol. "Gemzell-Danielsson K, Berger C, P G L L. Emergency contraception -- mechanisms of action. Contraception. 2013 Mar;87(3):300-8. PMID: 23114735.

Yuan P, Chen B, Huang Y, et al. Long-term regression of experimental endometriosis in a rat model treated with local application of levonorgestrel-loaded biodegradable microspheres. Hum Reprod. 2012 Jul;27(7):2089-95. PMID: 22563024.

Sarkar NN. The emergency contraceptive drug, levonorgestrel: a review of post-coital oral and peri-coital vaginal administration for prevention of pregnancy. J Obstet Gynaecol. 2011 Nov;31(8):703-7. PMID: 22085058.

" T Not dangerous goods.

LKT L1684 Levonorgestrel 500 mg 254.9 Synthetic progestogen; contraceptive. 17-Ethynyl-18-methyl-19-nortestosterone D(−) Norgestrel; Microlut; Microval; Norgeston; Norlevo; Norplant 797-63-7 ≥98% 312.45 C21H28O2 CCC12CCC3C(C1CCC2(C#C)O)CCC4=CC(=O)CCC34 Ambient Ambient Insoluble in water. Slightly soluble in alcohol. "Gemzell-Danielsson K, Berger C, P G L L. Emergency contraception -- mechanisms of action. Contraception. 2013 Mar;87(3):300-8. PMID: 23114735.

Yuan P, Chen B, Huang Y, et al. Long-term regression of experimental endometriosis in a rat model treated with local application of levonorgestrel-loaded biodegradable microspheres. Hum Reprod. 2012 Jul;27(7):2089-95. PMID: 22563024.

Sarkar NN. The emergency contraceptive drug, levonorgestrel: a review of post-coital oral and peri-coital vaginal administration for prevention of pregnancy. J Obstet Gynaecol. 2011 Nov;31(8):703-7. PMID: 22085058.

" T Not dangerous goods.

LKT L1684 Levonorgestrel 1 g 494.8 Synthetic progestogen; contraceptive. 17-Ethynyl-18-methyl-19-nortestosterone D(−) Norgestrel; Microlut; Microval; Norgeston; Norlevo; Norplant 797-63-7 ≥98% 312.45 C21H28O2 CCC12CCC3C(C1CCC2(C#C)O)CCC4=CC(=O)CCC34 Ambient Ambient Insoluble in water. Slightly soluble in alcohol. "Gemzell-Danielsson K, Berger C, P G L L. Emergency contraception -- mechanisms of action. Contraception. 2013 Mar;87(3):300-8. PMID: 23114735.

Yuan P, Chen B, Huang Y, et al. Long-term regression of experimental endometriosis in a rat model treated with local application of levonorgestrel-loaded biodegradable microspheres. Hum Reprod. 2012 Jul;27(7):2089-95. PMID: 22563024.

Sarkar NN. The emergency contraceptive drug, levonorgestrel: a review of post-coital oral and peri-coital vaginal administration for prevention of pregnancy. J Obstet Gynaecol. 2011 Nov;31(8):703-7. PMID: 22085058.

" T Not dangerous goods.

LKT L1735 Levitide 1 mg 60 Antimicrobial peptide found in amphibians. 114281-19-5 ≥95% 1542.88 C66H119N21O19S CCC(C)C(C(=O)NCC(=O)NC(C(C)O)C(=O)NC(CC(C)C)C(=O)NC(C(C)O)C(=O)NC(CO)C(=O)NC(CCCCN)C(=O)NC(CCCN=C(N)N)C(=O)NC(C(C)CC)C(=O)NC(CCCCN)C(=O)NC(CCC(=O)N)C(=O)N)NC(=O)C(CCSC)NC(=O)CNC(=O)C1CCC(=O)N1 Ambient -20°C "Langerveld AJ, Celestine R, Zaya R, et al. Chronic exposure to high levels of atrazine alters expression of genes that regulate immune and growth-related functions in developing Xenopus laevis tadpoles. Environ Res. 2009 May;109(4):379-89. PMID: 19272595.

Poulter L, Terry AS, Williams DH, et al. Levitide, a neurohormone-like peptide from the skin of Xenopus laevis. Peptide and peptide precursor cDNA sequences. J Biol Chem. 1988 Mar 5;263(7):3279-83. PMID: 2830279.

" Not dangerous goods.

LKT L1735 Levitide 2 mg 101.9 Antimicrobial peptide found in amphibians. 114281-19-5 ≥95% 1542.88 C66H119N21O19S CCC(C)C(C(=O)NCC(=O)NC(C(C)O)C(=O)NC(CC(C)C)C(=O)NC(C(C)O)C(=O)NC(CO)C(=O)NC(CCCCN)C(=O)NC(CCCN=C(N)N)C(=O)NC(C(C)CC)C(=O)NC(CCCCN)C(=O)NC(CCC(=O)N)C(=O)N)NC(=O)C(CCSC)NC(=O)CNC(=O)C1CCC(=O)N1 Ambient -20°C "Langerveld AJ, Celestine R, Zaya R, et al. Chronic exposure to high levels of atrazine alters expression of genes that regulate immune and growth-related functions in developing Xenopus laevis tadpoles. Environ Res. 2009 May;109(4):379-89. PMID: 19272595.

Poulter L, Terry AS, Williams DH, et al. Levitide, a neurohormone-like peptide from the skin of Xenopus laevis. Peptide and peptide precursor cDNA sequences. J Biol Chem. 1988 Mar 5;263(7):3279-83. PMID: 2830279.

" Not dangerous goods.

LKT L1735 Levitide 5 mg 180 Antimicrobial peptide found in amphibians. 114281-19-5 ≥95% 1542.88 C66H119N21O19S CCC(C)C(C(=O)NCC(=O)NC(C(C)O)C(=O)NC(CC(C)C)C(=O)NC(C(C)O)C(=O)NC(CO)C(=O)NC(CCCCN)C(=O)NC(CCCN=C(N)N)C(=O)NC(C(C)CC)C(=O)NC(CCCCN)C(=O)NC(CCC(=O)N)C(=O)N)NC(=O)C(CCSC)NC(=O)CNC(=O)C1CCC(=O)N1 Ambient -20°C "Langerveld AJ, Celestine R, Zaya R, et al. Chronic exposure to high levels of atrazine alters expression of genes that regulate immune and growth-related functions in developing Xenopus laevis tadpoles. Environ Res. 2009 May;109(4):379-89. PMID: 19272595.

Poulter L, Terry AS, Williams DH, et al. Levitide, a neurohormone-like peptide from the skin of Xenopus laevis. Peptide and peptide precursor cDNA sequences. J Biol Chem. 1988 Mar 5;263(7):3279-83. PMID: 2830279.

" Not dangerous goods.

LKT T1654 Tenoxicam 250 mg 58.5 NSAID; COX-1/2 inhibitor. 4-Hydroxy-2-methyl-N-2-pyridinyl-2H-thieno[2,3-e]- 1,2-thiazine-3-carboxamide 1,1-dioxide Alganex; Dolmen; Liman; Mobiflex; Rexalgan; Tilcotil 59804-37-4 ≥98% 337.38 C13H11N3O4S2 CN1C(=C(C2=C(S1(=O)=O)C=CS2)O)C(=O)NC3=CC=CC=N3 Ambient Ambient Soluble in DMSO, chloroform and methylene chloride. "Tasaki Y, Yamamoto J, Omura T, et al. Oxicam structure in non-steroidal anti-inflammatory drugs is essential to exhibit Akt-mediated neuroprotection against 1-methyl-4-phenyl pyridinium-induced cytotoxicity. Eur J Pharmacol. 2012 Feb 15;676(1-3):57-63. PMID: 22182582.

Suleyman H, Halici Z, Cadirci E, et al. Indirect role of beta2-adrenergic receptors in the mechanism of anti-inflammatory action of NSAIDS. J Physiol Pharmacol. 2008 Dec;59(4):661-72. PMID: 19212002.

Maffei Facino RM, Carini M, Saibene L. Scavenging of free radicals by tenoxicam: a participating mechanism in the antirheumatic/antiinflammatory efficacy of the drug. Arch Pharm (Weinheim). 1996 Oct;329(10):457-63. PMID: 8933748.

" T "UN number: 2811     Class: 6.1     Packing Group: III

Proper shipping name: Toxic solid, organic, n.o.s. (Tenoxicam)"

LKT T1654 Tenoxicam 1 g 152.7 NSAID; COX-1/2 inhibitor. 4-Hydroxy-2-methyl-N-2-pyridinyl-2H-thieno[2,3-e]- 1,2-thiazine-3-carboxamide 1,1-dioxide Alganex; Dolmen; Liman; Mobiflex; Rexalgan; Tilcotil 59804-37-4 ≥98% 337.38 C13H11N3O4S2 CN1C(=C(C2=C(S1(=O)=O)C=CS2)O)C(=O)NC3=CC=CC=N3 Ambient Ambient Soluble in DMSO, chloroform and methylene chloride. "Tasaki Y, Yamamoto J, Omura T, et al. Oxicam structure in non-steroidal anti-inflammatory drugs is essential to exhibit Akt-mediated neuroprotection against 1-methyl-4-phenyl pyridinium-induced cytotoxicity. Eur J Pharmacol. 2012 Feb 15;676(1-3):57-63. PMID: 22182582.

Suleyman H, Halici Z, Cadirci E, et al. Indirect role of beta2-adrenergic receptors in the mechanism of anti-inflammatory action of NSAIDS. J Physiol Pharmacol. 2008 Dec;59(4):661-72. PMID: 19212002.

Maffei Facino RM, Carini M, Saibene L. Scavenging of free radicals by tenoxicam: a participating mechanism in the antirheumatic/antiinflammatory efficacy of the drug. Arch Pharm (Weinheim). 1996 Oct;329(10):457-63. PMID: 8933748.

" T "UN number: 2811     Class: 6.1     Packing Group: III

Proper shipping name: Toxic solid, organic, n.o.s. (Tenoxicam)"

LKT T1654 Tenoxicam 5 g 508.3 NSAID; COX-1/2 inhibitor. 4-Hydroxy-2-methyl-N-2-pyridinyl-2H-thieno[2,3-e]- 1,2-thiazine-3-carboxamide 1,1-dioxide Alganex; Dolmen; Liman; Mobiflex; Rexalgan; Tilcotil 59804-37-4 ≥98% 337.38 C13H11N3O4S2 CN1C(=C(C2=C(S1(=O)=O)C=CS2)O)C(=O)NC3=CC=CC=N3 Ambient Ambient Soluble in DMSO, chloroform and methylene chloride. "Tasaki Y, Yamamoto J, Omura T, et al. Oxicam structure in non-steroidal anti-inflammatory drugs is essential to exhibit Akt-mediated neuroprotection against 1-methyl-4-phenyl pyridinium-induced cytotoxicity. Eur J Pharmacol. 2012 Feb 15;676(1-3):57-63. PMID: 22182582.

Suleyman H, Halici Z, Cadirci E, et al. Indirect role of beta2-adrenergic receptors in the mechanism of anti-inflammatory action of NSAIDS. J Physiol Pharmacol. 2008 Dec;59(4):661-72. PMID: 19212002.

Maffei Facino RM, Carini M, Saibene L. Scavenging of free radicals by tenoxicam: a participating mechanism in the antirheumatic/antiinflammatory efficacy of the drug. Arch Pharm (Weinheim). 1996 Oct;329(10):457-63. PMID: 8933748.

" T "UN number: 2811     Class: 6.1     Packing Group: III

Proper shipping name: Toxic solid, organic, n.o.s. (Tenoxicam)"

LKT L1780 Levocetirizine Dihydrochloride 1 g 52.6 L-isomer of cetirizine; histamine H1 antagonist. "Acetic acid, (2-(4-((R)-(4-chlorophenyl)phenylmethyl)-1-

piperazinyl)ethoxy)- hydrochloride" (−)-Cetirizine; Xusal; Xyzal 130018-87-0 ≥98% 461.81 C21H25ClN2O3 2HCl C1CN(CCN1CCOCC(=O)O)C(C2=CC=CC=C2)C3=CC=C(C=C3)Cl.Cl.Cl Ambient Ambient "García-Zepeda S, Estrada-Muñiz E, Elizondo G, et al. Levocetirizine inhibits migration of immune cells to lymph nodes and induces treg cells in a murine type I allergic conjunctivitis model. Open Ophthalmol J. 2012;6:129-36. PMID: 23284599.

Mahmoud F, Arifhodzic N, Haines D, et al. Levocetirizine modulates lymphocyte activation in patients with allergic rhinitis. J Pharmacol Sci. 2008 Oct;108(2):149-56. PMID: 18946193.

" "UN number: 3077     Class: 9    Packing Group: III

Proper shipping name: Environmentally hazardous substance, solid, n.o.s. (Levocetirizine dihydrochloride)"

LKT L1780 Levocetirizine Dihydrochloride 5 g 109.2 L-isomer of cetirizine; histamine H1 antagonist. "Acetic acid, (2-(4-((R)-(4-chlorophenyl)phenylmethyl)-1-

piperazinyl)ethoxy)- hydrochloride" (−)-Cetirizine; Xusal; Xyzal 130018-87-0 ≥98% 461.81 C21H25ClN2O3 2HCl C1CN(CCN1CCOCC(=O)O)C(C2=CC=CC=C2)C3=CC=C(C=C3)Cl.Cl.Cl Ambient Ambient "García-Zepeda S, Estrada-Muñiz E, Elizondo G, et al. Levocetirizine inhibits migration of immune cells to lymph nodes and induces treg cells in a murine type I allergic conjunctivitis model. Open Ophthalmol J. 2012;6:129-36. PMID: 23284599.

Mahmoud F, Arifhodzic N, Haines D, et al. Levocetirizine modulates lymphocyte activation in patients with allergic rhinitis. J Pharmacol Sci. 2008 Oct;108(2):149-56. PMID: 18946193.

" "UN number: 3077     Class: 9    Packing Group: III

Proper shipping name: Environmentally hazardous substance, solid, n.o.s. (Levocetirizine dihydrochloride)"

LKT L1780 Levocetirizine Dihydrochloride 25 g 420.1 L-isomer of cetirizine; histamine H1 antagonist. "Acetic acid, (2-(4-((R)-(4-chlorophenyl)phenylmethyl)-1-

piperazinyl)ethoxy)- hydrochloride" (−)-Cetirizine; Xusal; Xyzal 130018-87-0 ≥98% 461.81 C21H25ClN2O3 2HCl C1CN(CCN1CCOCC(=O)O)C(C2=CC=CC=C2)C3=CC=C(C=C3)Cl.Cl.Cl Ambient Ambient "García-Zepeda S, Estrada-Muñiz E, Elizondo G, et al. Levocetirizine inhibits migration of immune cells to lymph nodes and induces treg cells in a murine type I allergic conjunctivitis model. Open Ophthalmol J. 2012;6:129-36. PMID: 23284599.

Mahmoud F, Arifhodzic N, Haines D, et al. Levocetirizine modulates lymphocyte activation in patients with allergic rhinitis. J Pharmacol Sci. 2008 Oct;108(2):149-56. PMID: 18946193.

" "UN number: 3077     Class: 9    Packing Group: III

Proper shipping name: Environmentally hazardous substance, solid, n.o.s. (Levocetirizine dihydrochloride)"

LKT T1652 Teniposide 25 mg 67.9 Podophyllotoxin derivative; topoisomerase II inhibitor. [5R-[5α,5aβ,8aα,9β-(R*)]]-5,8,8a,9-Tetrahydro-5-(4- hydroxy-3,5-dimethoxyphenyl)-9-[[4,6-O-(2-thienyl- methylene)-β-D-glucopyranosyl]oxyfuro[3',4':6,7]- naphtho[2,3-d]-1,3-dioxol-6(5aH)-one ETP; Vehem-Sandox; Vumon 29767-20-2 ≥97% 656.66 C32H32O13S COC1=CC(=CC(=C1O)OC)C2C3C(COC3=O)C(C4=CC5=C(C=C24)OCO5)OC6C(C(C7C(O6)COC(O7)C8=CC=CS8)O)O Ambient Ambient Soluble in acetone or dimethylformamide. "You Y. Podophyllotoxin derivatives: current synthetic approaches for new anticancer agents. Curr Pharm Des. 2005;11(13):1695-717. PMID: 15892669.

Han YH, Austin MJ, Pommier Y, et al. Small deletion and insertion mutations induced by the topoisomerase II inhibitor teniposide in CHO cells and comparison with sites of drug-stimulated DNA cleavage in vitro. J Mol Biol. 1993 Jan 5;229(1):52-66. PMID: 8380617.

" Not dangerous goods.

LKT T1652 Teniposide 100 mg 203.8 Podophyllotoxin derivative; topoisomerase II inhibitor. [5R-[5α,5aβ,8aα,9β-(R*)]]-5,8,8a,9-Tetrahydro-5-(4- hydroxy-3,5-dimethoxyphenyl)-9-[[4,6-O-(2-thienyl- methylene)-β-D-glucopyranosyl]oxyfuro[3',4':6,7]- naphtho[2,3-d]-1,3-dioxol-6(5aH)-one ETP; Vehem-Sandox; Vumon 29767-20-2 ≥97% 656.66 C32H32O13S COC1=CC(=CC(=C1O)OC)C2C3C(COC3=O)C(C4=CC5=C(C=C24)OCO5)OC6C(C(C7C(O6)COC(O7)C8=CC=CS8)O)O Ambient Ambient Soluble in acetone or dimethylformamide. "You Y. Podophyllotoxin derivatives: current synthetic approaches for new anticancer agents. Curr Pharm Des. 2005;11(13):1695-717. PMID: 15892669.

Han YH, Austin MJ, Pommier Y, et al. Small deletion and insertion mutations induced by the topoisomerase II inhibitor teniposide in CHO cells and comparison with sites of drug-stimulated DNA cleavage in vitro. J Mol Biol. 1993 Jan 5;229(1):52-66. PMID: 8380617.

" Not dangerous goods.

LKT L1782 Levodopa 1 g 40.7 Endogenous catecholamine precursor, also found in Mucuna. 3-Hydroxy-L-tyrosine Bendopa; Dopaflex; Dopaidan; Doparl; Dopaston; Eldopatec; L-DOPA; Maipedopa; Parda; Veldopa 59-92-7 ≥98% 197.19 C9H11NO4 C1=CC(=C(C=C1CC(C(=O)O)N)O)O Keep dry! In presence of moisture, rapid oxidation occurs. Ambient Ambient Soluble in water, dil HCl, and formic acid.Practically insoluble in ethanol, benzene, chloroform and ethyl acetate. "Pahwa R, Lyons KE. Treatment of early Parkinson's disease. Curr Opin Neurol. 2014 Jun 19. [Epub ahead of print]. PMID: 24950010.

Pd Med Collaborative Group. Long-term effectiveness of dopamine agonists and monoamine oxidase B inhibitors compared with levodopa as initial treatment for Parkinson's disease (PD MED): a large, open-label, pragmatic randomised trial. Lancet. 2014 Jun 10. [Epub ahead of print]. PMID: 24928805.

" Xn Not dangerous goods.

LKT L1782 Levodopa 5 g 61.1 Endogenous catecholamine precursor, also found in Mucuna. 3-Hydroxy-L-tyrosine Bendopa; Dopaflex; Dopaidan; Doparl; Dopaston; Eldopatec; L-DOPA; Maipedopa; Parda; Veldopa 59-92-7 ≥98% 197.19 C9H11NO4 C1=CC(=C(C=C1CC(C(=O)O)N)O)O Keep dry! In presence of moisture, rapid oxidation occurs. Ambient Ambient Soluble in water, dil HCl, and formic acid.Practically insoluble in ethanol, benzene, chloroform and ethyl acetate. "Pahwa R, Lyons KE. Treatment of early Parkinson's disease. Curr Opin Neurol. 2014 Jun 19. [Epub ahead of print]. PMID: 24950010.

Pd Med Collaborative Group. Long-term effectiveness of dopamine agonists and monoamine oxidase B inhibitors compared with levodopa as initial treatment for Parkinson's disease (PD MED): a large, open-label, pragmatic randomised trial. Lancet. 2014 Jun 10. [Epub ahead of print]. PMID: 24928805.

" Xn Not dangerous goods.

LKT T1652 Teniposide 500 mg 611.5 Podophyllotoxin derivative; topoisomerase II inhibitor. [5R-[5α,5aβ,8aα,9β-(R*)]]-5,8,8a,9-Tetrahydro-5-(4- hydroxy-3,5-dimethoxyphenyl)-9-[[4,6-O-(2-thienyl- methylene)-β-D-glucopyranosyl]oxyfuro[3',4':6,7]- naphtho[2,3-d]-1,3-dioxol-6(5aH)-one ETP; Vehem-Sandox; Vumon 29767-20-2 ≥97% 656.66 C32H32O13S COC1=CC(=CC(=C1O)OC)C2C3C(COC3=O)C(C4=CC5=C(C=C24)OCO5)OC6C(C(C7C(O6)COC(O7)C8=CC=CS8)O)O Ambient Ambient Soluble in acetone or dimethylformamide. "You Y. Podophyllotoxin derivatives: current synthetic approaches for new anticancer agents. Curr Pharm Des. 2005;11(13):1695-717. PMID: 15892669.

Han YH, Austin MJ, Pommier Y, et al. Small deletion and insertion mutations induced by the topoisomerase II inhibitor teniposide in CHO cells and comparison with sites of drug-stimulated DNA cleavage in vitro. J Mol Biol. 1993 Jan 5;229(1):52-66. PMID: 8380617.

" Not dangerous goods.

LKT L1782 Levodopa 10 g 115.5 Endogenous catecholamine precursor, also found in Mucuna. 3-Hydroxy-L-tyrosine Bendopa; Dopaflex; Dopaidan; Doparl; Dopaston; Eldopatec; L-DOPA; Maipedopa; Parda; Veldopa 59-92-7 ≥98% 197.19 C9H11NO4 C1=CC(=C(C=C1CC(C(=O)O)N)O)O Keep dry! In presence of moisture, rapid oxidation occurs. Ambient Ambient Soluble in water, dil HCl, and formic acid.Practically insoluble in ethanol, benzene, chloroform and ethyl acetate. "Pahwa R, Lyons KE. Treatment of early Parkinson's disease. Curr Opin Neurol. 2014 Jun 19. [Epub ahead of print]. PMID: 24950010.

Pd Med Collaborative Group. Long-term effectiveness of dopamine agonists and monoamine oxidase B inhibitors compared with levodopa as initial treatment for Parkinson's disease (PD MED): a large, open-label, pragmatic randomised trial. Lancet. 2014 Jun 10. [Epub ahead of print]. PMID: 24928805.

" Xn Not dangerous goods.

LKT L1785 Levofloxacin Hemihydrate 500 mg 33.9 Fluoroquinolone, S-(-) isomer of ofloxacin; topoisomerase IV and bacterial DNA gyrase inhibitor. S-(−)-Ofloxacin; ≥98% 370.4 C18H20FN3O4 1/2H2O CC1COC2=C3N1C=C(C(=O)C3=CC(=C2N4CCN(CC4)C)F)C(=O)O Ambient Ambient "Fu Y, Zhang W, Wang H, et al. Specific patterns of gyrA mutations determine the resistance difference to ciprofloxacin and levofloxacin in Klebsiella pneumoniae and Escherichia coli. BMC Infect Dis. 2013 Jan 7;13:8. PMID: 23295059.

Gouvea LR, Garcia LS, Lachter DR, et al. Atypical fluoroquinolone gold(III) chelates as potential anticancer agents: relevance of DNA and protein interactions for their mechanism of action. Eur J Med Chem. 2012 Sep;55:67-73. PMID: 22835721.

Drlica K, Zhao X. DNA gyrase, topoisomerase IV, and the 4-quinolones. Microbiol Mol Biol Rev. 1997 Sep;61(3):377-92. PMID: 9293187.

" Xn Not dangerous goods.

LKT L1785 Levofloxacin Hemihydrate 1 g 47.6 Fluoroquinolone, S-(-) isomer of ofloxacin; topoisomerase IV and bacterial DNA gyrase inhibitor. S-(−)-Ofloxacin; ≥98% 370.4 C18H20FN3O4 1/2H2O CC1COC2=C3N1C=C(C(=O)C3=CC(=C2N4CCN(CC4)C)F)C(=O)O Ambient Ambient "Fu Y, Zhang W, Wang H, et al. Specific patterns of gyrA mutations determine the resistance difference to ciprofloxacin and levofloxacin in Klebsiella pneumoniae and Escherichia coli. BMC Infect Dis. 2013 Jan 7;13:8. PMID: 23295059.

Gouvea LR, Garcia LS, Lachter DR, et al. Atypical fluoroquinolone gold(III) chelates as potential anticancer agents: relevance of DNA and protein interactions for their mechanism of action. Eur J Med Chem. 2012 Sep;55:67-73. PMID: 22835721.

Drlica K, Zhao X. DNA gyrase, topoisomerase IV, and the 4-quinolones. Microbiol Mol Biol Rev. 1997 Sep;61(3):377-92. PMID: 9293187.

" Xn Not dangerous goods.

LKT L1785 Levofloxacin Hemihydrate 5 g 169.9 Fluoroquinolone, S-(-) isomer of ofloxacin; topoisomerase IV and bacterial DNA gyrase inhibitor. S-(−)-Ofloxacin; ≥98% 370.4 C18H20FN3O4 1/2H2O CC1COC2=C3N1C=C(C(=O)C3=CC(=C2N4CCN(CC4)C)F)C(=O)O Ambient Ambient "Fu Y, Zhang W, Wang H, et al. Specific patterns of gyrA mutations determine the resistance difference to ciprofloxacin and levofloxacin in Klebsiella pneumoniae and Escherichia coli. BMC Infect Dis. 2013 Jan 7;13:8. PMID: 23295059.

Gouvea LR, Garcia LS, Lachter DR, et al. Atypical fluoroquinolone gold(III) chelates as potential anticancer agents: relevance of DNA and protein interactions for their mechanism of action. Eur J Med Chem. 2012 Sep;55:67-73. PMID: 22835721.

Drlica K, Zhao X. DNA gyrase, topoisomerase IV, and the 4-quinolones. Microbiol Mol Biol Rev. 1997 Sep;61(3):377-92. PMID: 9293187.

" Xn Not dangerous goods.

LKT T1644 Telmisartan 50 mg 95.1 AT-II antagonist, PPARγ/δ modulator. 4'-[(1,4'-Dimethyl-2'-propyl[2,6'-bi-1H-benzimidazol]-1'-yl)methyl][1,1'-biphenyl]-2-carboxylic acid BIBR 277; Micardis; Pritor 144701-48-4 ≥98% 514.63 C33H30N4O2 CCCC1=NC2=C(C=C(C=C2N1CC3=CC=C(C=C3)C4=CC=CC=C4C(=O)O)C5=NC6=CC=CC=C6N5C)C Ambient Ambient Soluble in DMSO (1.2mg/mL). Insoluble in water. Chloroform. "Xu S, Song H, Huang M, et al. Telmisartan inhibits the proinflammatory effects of homocysteine on human endothelial cells through activation of the peroxisome proliferator-activated receptor-δ pathway. Int J Mol Med. 2014 Sep;34(3):828-34. PMID: 24994548.

Sueta D, Koibuchi N, Hasegawa Y, et al. Telmisartan Exerts Sustained Blood Pressure Control and Reduces Blood Pressure Variability in Metabolic Syndrome by Inhibiting Sympathetic Activity. Am J Hypertens. 2014 May 28. [Epub ahead of print]. PMID: 24871627.

Feng X, Luo Z, Ma L, et al. Angiotensin II receptor blocker telmisartan enhances running endurance of skeletal muscle through activation of the PPAR-δ/AMPK pathway. J Cell Mol Med. 2011 Jul;15(7):1572-81. PMID: 20477906.

Inoue T, Taguchi I, Abe S, et al. Inhibition of intestinal cholesterol absorption might explain cholesterol-lowering effect of telmisartan. J Clin Pharm Ther. 2011 Feb;36(1):103-10. PMID: 21198725.

Benson SC, Pershadsingh HA, Ho CI, et al. Identification of telmisartan as a unique angiotensin II receptor antagonist with selective PPARgamma-modulating activity. Hypertension. 2004 May;43(5):993-1002. PMID: 15007034.

Okada M, Kosaka N, Hoshino Y, et al. Effects of captopril and telmisartan on matrix metalloproteinase-2 and -9 expressions and development of left ventricular fibrosis induced by isoprenaline in rats. Biol Pharm Bull. 2010;33(9):1517-1521. PMID: 20823567.

" None Not dangerous goods.

LKT T1644 Telmisartan 100 mg 163.2 AT-II antagonist, PPARγ/δ modulator. 4'-[(1,4'-Dimethyl-2'-propyl[2,6'-bi-1H-benzimidazol]-1'-yl)methyl][1,1'-biphenyl]-2-carboxylic acid BIBR 277; Micardis; Pritor 144701-48-4 ≥98% 514.63 C33H30N4O2 CCCC1=NC2=C(C=C(C=C2N1CC3=CC=C(C=C3)C4=CC=CC=C4C(=O)O)C5=NC6=CC=CC=C6N5C)C Ambient Ambient Soluble in DMSO (1.2mg/mL). Insoluble in water. Chloroform. "Xu S, Song H, Huang M, et al. Telmisartan inhibits the proinflammatory effects of homocysteine on human endothelial cells through activation of the peroxisome proliferator-activated receptor-δ pathway. Int J Mol Med. 2014 Sep;34(3):828-34. PMID: 24994548.

Sueta D, Koibuchi N, Hasegawa Y, et al. Telmisartan Exerts Sustained Blood Pressure Control and Reduces Blood Pressure Variability in Metabolic Syndrome by Inhibiting Sympathetic Activity. Am J Hypertens. 2014 May 28. [Epub ahead of print]. PMID: 24871627.

Feng X, Luo Z, Ma L, et al. Angiotensin II receptor blocker telmisartan enhances running endurance of skeletal muscle through activation of the PPAR-δ/AMPK pathway. J Cell Mol Med. 2011 Jul;15(7):1572-81. PMID: 20477906.

Inoue T, Taguchi I, Abe S, et al. Inhibition of intestinal cholesterol absorption might explain cholesterol-lowering effect of telmisartan. J Clin Pharm Ther. 2011 Feb;36(1):103-10. PMID: 21198725.

Benson SC, Pershadsingh HA, Ho CI, et al. Identification of telmisartan as a unique angiotensin II receptor antagonist with selective PPARgamma-modulating activity. Hypertension. 2004 May;43(5):993-1002. PMID: 15007034.

Okada M, Kosaka N, Hoshino Y, et al. Effects of captopril and telmisartan on matrix metalloproteinase-2 and -9 expressions and development of left ventricular fibrosis induced by isoprenaline in rats. Biol Pharm Bull. 2010;33(9):1517-1521. PMID: 20823567.

" None Not dangerous goods.

LKT T1644 Telmisartan 500 mg 475.7 AT-II antagonist, PPARγ/δ modulator. 4'-[(1,4'-Dimethyl-2'-propyl[2,6'-bi-1H-benzimidazol]-1'-yl)methyl][1,1'-biphenyl]-2-carboxylic acid BIBR 277; Micardis; Pritor 144701-48-4 ≥98% 514.63 C33H30N4O2 CCCC1=NC2=C(C=C(C=C2N1CC3=CC=C(C=C3)C4=CC=CC=C4C(=O)O)C5=NC6=CC=CC=C6N5C)C Ambient Ambient Soluble in DMSO (1.2mg/mL). Insoluble in water. Chloroform. "Xu S, Song H, Huang M, et al. Telmisartan inhibits the proinflammatory effects of homocysteine on human endothelial cells through activation of the peroxisome proliferator-activated receptor-δ pathway. Int J Mol Med. 2014 Sep;34(3):828-34. PMID: 24994548.

Sueta D, Koibuchi N, Hasegawa Y, et al. Telmisartan Exerts Sustained Blood Pressure Control and Reduces Blood Pressure Variability in Metabolic Syndrome by Inhibiting Sympathetic Activity. Am J Hypertens. 2014 May 28. [Epub ahead of print]. PMID: 24871627.

Feng X, Luo Z, Ma L, et al. Angiotensin II receptor blocker telmisartan enhances running endurance of skeletal muscle through activation of the PPAR-δ/AMPK pathway. J Cell Mol Med. 2011 Jul;15(7):1572-81. PMID: 20477906.

Inoue T, Taguchi I, Abe S, et al. Inhibition of intestinal cholesterol absorption might explain cholesterol-lowering effect of telmisartan. J Clin Pharm Ther. 2011 Feb;36(1):103-10. PMID: 21198725.

Benson SC, Pershadsingh HA, Ho CI, et al. Identification of telmisartan as a unique angiotensin II receptor antagonist with selective PPARgamma-modulating activity. Hypertension. 2004 May;43(5):993-1002. PMID: 15007034.

Okada M, Kosaka N, Hoshino Y, et al. Effects of captopril and telmisartan on matrix metalloproteinase-2 and -9 expressions and development of left ventricular fibrosis induced by isoprenaline in rats. Biol Pharm Bull. 2010;33(9):1517-1521. PMID: 20823567.

" None Not dangerous goods.

LKT L1786 Levofloxacin Hydrochloride Monohydrate 500 mg 33.9 Fluoroquinolone, S-(-) isomer of ofloxacin; topoisomerase IV and bacterial DNA gyrase inhibitor. S-(−)-Ofloxacin; Levofloxacin; Cravit; Tavanic; Quixin 100986-85-4 ≥90% 415.84 C18H20FN3O4 HCl H2O CC1COC2=C3N1C=C(C(=O)C3=CC(=C2N4CCN(CC4)C)F)C(=O)O Ambient Ambient Water(25mg/mL) "Fu Y, Zhang W, Wang H, et al. Specific patterns of gyrA mutations determine the resistance difference to ciprofloxacin and levofloxacin in Klebsiella pneumoniae and Escherichia coli. BMC Infect Dis. 2013 Jan 7;13:8. PMID: 23295059.

Gouvea LR, Garcia LS, Lachter DR, et al. Atypical fluoroquinolone gold(III) chelates as potential anticancer agents: relevance of DNA and protein interactions for their mechanism of action. Eur J Med Chem. 2012 Sep;55:67-73. PMID: 22835721.

Drlica K, Zhao X. DNA gyrase, topoisomerase IV, and the 4-quinolones. Microbiol Mol Biol Rev. 1997 Sep;61(3):377-92. PMID: 9293187.

" Xn Not dangerous goods.

LKT L1786 Levofloxacin Hydrochloride Monohydrate 1 g 43.5 Fluoroquinolone, S-(-) isomer of ofloxacin; topoisomerase IV and bacterial DNA gyrase inhibitor. S-(−)-Ofloxacin; Levofloxacin; Cravit; Tavanic; Quixin 100986-85-4 ≥90% 415.84 C18H20FN3O4 HCl H2O CC1COC2=C3N1C=C(C(=O)C3=CC(=C2N4CCN(CC4)C)F)C(=O)O Ambient Ambient Water(25mg/mL) "Fu Y, Zhang W, Wang H, et al. Specific patterns of gyrA mutations determine the resistance difference to ciprofloxacin and levofloxacin in Klebsiella pneumoniae and Escherichia coli. BMC Infect Dis. 2013 Jan 7;13:8. PMID: 23295059.

Gouvea LR, Garcia LS, Lachter DR, et al. Atypical fluoroquinolone gold(III) chelates as potential anticancer agents: relevance of DNA and protein interactions for their mechanism of action. Eur J Med Chem. 2012 Sep;55:67-73. PMID: 22835721.

Drlica K, Zhao X. DNA gyrase, topoisomerase IV, and the 4-quinolones. Microbiol Mol Biol Rev. 1997 Sep;61(3):377-92. PMID: 9293187.

" Xn Not dangerous goods.

LKT L1786 Levofloxacin Hydrochloride Monohydrate 5 g 101.9 Fluoroquinolone, S-(-) isomer of ofloxacin; topoisomerase IV and bacterial DNA gyrase inhibitor. S-(−)-Ofloxacin; Levofloxacin; Cravit; Tavanic; Quixin 100986-85-4 ≥90% 415.84 C18H20FN3O4 HCl H2O CC1COC2=C3N1C=C(C(=O)C3=CC(=C2N4CCN(CC4)C)F)C(=O)O Ambient Ambient Water(25mg/mL) "Fu Y, Zhang W, Wang H, et al. Specific patterns of gyrA mutations determine the resistance difference to ciprofloxacin and levofloxacin in Klebsiella pneumoniae and Escherichia coli. BMC Infect Dis. 2013 Jan 7;13:8. PMID: 23295059.

Gouvea LR, Garcia LS, Lachter DR, et al. Atypical fluoroquinolone gold(III) chelates as potential anticancer agents: relevance of DNA and protein interactions for their mechanism of action. Eur J Med Chem. 2012 Sep;55:67-73. PMID: 22835721.

Drlica K, Zhao X. DNA gyrase, topoisomerase IV, and the 4-quinolones. Microbiol Mol Biol Rev. 1997 Sep;61(3):377-92. PMID: 9293187.

" Xn Not dangerous goods.

LKT T1605 Tebuconazole 5 g 56.3 Triazole; 14-α demethylase inhibitor, voltage-gated Ca2+ channel blocker, potential aromatase inhibitor. 107534-96-3 ≥98% 307.82 C16H22ClN3O CC(C)(C)C(CCC1=CC=C(C=C1)Cl)(CN2C=NC=N2)O Ambient Ambient "Heusinkveld HJ, Molendijk J, van den Berg M, et al. Azole fungicides disturb intracellular Ca2+ in an additive manner in dopaminergic PC12 cells. Toxicol Sci. 2013 Aug;134(2):374-81. PMID: 23708404.

Kjærstad MB, Taxvig C, Nellemann C, et al. Endocrine disrupting effects in vitro of conazole antifungals used as pesticides and pharmaceuticals. Reprod Toxicol. 2010 Dec;30(4):573-82. PMID: 20708073.

Taxvig C, Vinggaard AM, Hass U, et al. Endocrine-disrupting properties in vivo of widely used azole fungicides. Int J Androl. 2008 Apr;31(2):170-7. PMID: 18067565.

Taxvig C, Hass U, Axelstad M, et al. Endocrine-disrupting activities in vivo of the fungicides tebuconazole and epoxiconazole. Toxicol Sci. 2007 Dec;100(2):464-73. PMID: 17785682.

Sanderson JT, Boerma J, Lansbergen GW, et al. Induction and inhibition of aromatase (CYP19) activity by various classes of pesticides in H295R human adrenocortical carcinoma cells. Toxicol Appl Pharmacol. 2002 Jul 1;182(1):44-54. PMID: 12127262.

" Xn, N Not dangerous goods.

LKT T1605 Tebuconazole 10 g 84.3 Triazole; 14-α demethylase inhibitor, voltage-gated Ca2+ channel blocker, potential aromatase inhibitor. 107534-96-3 ≥98% 307.82 C16H22ClN3O CC(C)(C)C(CCC1=CC=C(C=C1)Cl)(CN2C=NC=N2)O Ambient Ambient "Heusinkveld HJ, Molendijk J, van den Berg M, et al. Azole fungicides disturb intracellular Ca2+ in an additive manner in dopaminergic PC12 cells. Toxicol Sci. 2013 Aug;134(2):374-81. PMID: 23708404.

Kjærstad MB, Taxvig C, Nellemann C, et al. Endocrine disrupting effects in vitro of conazole antifungals used as pesticides and pharmaceuticals. Reprod Toxicol. 2010 Dec;30(4):573-82. PMID: 20708073.

Taxvig C, Vinggaard AM, Hass U, et al. Endocrine-disrupting properties in vivo of widely used azole fungicides. Int J Androl. 2008 Apr;31(2):170-7. PMID: 18067565.

Taxvig C, Hass U, Axelstad M, et al. Endocrine-disrupting activities in vivo of the fungicides tebuconazole and epoxiconazole. Toxicol Sci. 2007 Dec;100(2):464-73. PMID: 17785682.

Sanderson JT, Boerma J, Lansbergen GW, et al. Induction and inhibition of aromatase (CYP19) activity by various classes of pesticides in H295R human adrenocortical carcinoma cells. Toxicol Appl Pharmacol. 2002 Jul 1;182(1):44-54. PMID: 12127262.

" Xn, N Not dangerous goods.

LKT T1605 Tebuconazole 100 g 328.1 Triazole; 14-α demethylase inhibitor, voltage-gated Ca2+ channel blocker, potential aromatase inhibitor. 107534-96-3 ≥98% 307.82 C16H22ClN3O CC(C)(C)C(CCC1=CC=C(C=C1)Cl)(CN2C=NC=N2)O Ambient Ambient "Heusinkveld HJ, Molendijk J, van den Berg M, et al. Azole fungicides disturb intracellular Ca2+ in an additive manner in dopaminergic PC12 cells. Toxicol Sci. 2013 Aug;134(2):374-81. PMID: 23708404.

Kjærstad MB, Taxvig C, Nellemann C, et al. Endocrine disrupting effects in vitro of conazole antifungals used as pesticides and pharmaceuticals. Reprod Toxicol. 2010 Dec;30(4):573-82. PMID: 20708073.

Taxvig C, Vinggaard AM, Hass U, et al. Endocrine-disrupting properties in vivo of widely used azole fungicides. Int J Androl. 2008 Apr;31(2):170-7. PMID: 18067565.

Taxvig C, Hass U, Axelstad M, et al. Endocrine-disrupting activities in vivo of the fungicides tebuconazole and epoxiconazole. Toxicol Sci. 2007 Dec;100(2):464-73. PMID: 17785682.

Sanderson JT, Boerma J, Lansbergen GW, et al. Induction and inhibition of aromatase (CYP19) activity by various classes of pesticides in H295R human adrenocortical carcinoma cells. Toxicol Appl Pharmacol. 2002 Jul 1;182(1):44-54. PMID: 12127262.

" Xn, N Not dangerous goods.

LKT L1817 Leflunomide 100 mg 67.9 AhR agonist, dihydroorotate dehydrogenase inhibitor. "5-Methyl-N-[4-(trifluoromethyl)phenyl]-4-

isoxazolecarboxamide" HWA-486; Arava  75706-12-6 ≥98% 270.21 C12H9F3N2O2 CC1=C(C=NO1)C(=O)NC2=CC=C(C=C2)C(F)(F)F Protect from light. Ambient -20°C Soluble in DMSO or methanol. "Qi R, Hua-Song Z, Xiao-Feng Z. Leflunomide inhibits the apoptosis of human embryonic lung fibroblasts infected by human cytomegalovirus. Eur J Med Res. 2013 Feb 1;18:3. PMID: 23369524.

O'Donnell EF, Kopparapu PR, Koch DC, et al. The aryl hydrocarbon receptor mediates leflunomide-induced growth inhibition of melanoma cells. PLoS One. 2012;7(7):e40926. PMID: 22815870.

Bernhoff E, Tylden GD, Kjerpeseth LJ, et al. Leflunomide inhibition of BK virus replication in renal tubular epithelial cells. J Virol. 2010 Feb;84(4):2150-6. PMID: 19955306.

Pinto P, Dougados M. Leflunomide in clinical practice. Acta Reumatol Port. 2006 Jul-Sep;31(3):215-24. PMID: 17094333.

" Xn, Xi "UN number: 2811     Class: 6.1     Packing Group: III

Proper shipping name: Toxic solid, organic, n.o.s. (Leflunomide)"

LKT L1817 Leflunomide 500 mg 224.3 AhR agonist, dihydroorotate dehydrogenase inhibitor. "5-Methyl-N-[4-(trifluoromethyl)phenyl]-4-

isoxazolecarboxamide" HWA-486; Arava  75706-12-6 ≥98% 270.21 C12H9F3N2O2 CC1=C(C=NO1)C(=O)NC2=CC=C(C=C2)C(F)(F)F Protect from light. Ambient -20°C Soluble in DMSO or methanol. "Qi R, Hua-Song Z, Xiao-Feng Z. Leflunomide inhibits the apoptosis of human embryonic lung fibroblasts infected by human cytomegalovirus. Eur J Med Res. 2013 Feb 1;18:3. PMID: 23369524.

O'Donnell EF, Kopparapu PR, Koch DC, et al. The aryl hydrocarbon receptor mediates leflunomide-induced growth inhibition of melanoma cells. PLoS One. 2012;7(7):e40926. PMID: 22815870.

Bernhoff E, Tylden GD, Kjerpeseth LJ, et al. Leflunomide inhibition of BK virus replication in renal tubular epithelial cells. J Virol. 2010 Feb;84(4):2150-6. PMID: 19955306.

Pinto P, Dougados M. Leflunomide in clinical practice. Acta Reumatol Port. 2006 Jul-Sep;31(3):215-24. PMID: 17094333.

" Xn, Xi "UN number: 2811     Class: 6.1     Packing Group: III

Proper shipping name: Toxic solid, organic, n.o.s. (Leflunomide)"

LKT L1817 Leflunomide 1 g 339.8 AhR agonist, dihydroorotate dehydrogenase inhibitor. "5-Methyl-N-[4-(trifluoromethyl)phenyl]-4-

isoxazolecarboxamide" HWA-486; Arava  75706-12-6 ≥98% 270.21 C12H9F3N2O2 CC1=C(C=NO1)C(=O)NC2=CC=C(C=C2)C(F)(F)F Protect from light. Ambient -20°C Soluble in DMSO or methanol. "Qi R, Hua-Song Z, Xiao-Feng Z. Leflunomide inhibits the apoptosis of human embryonic lung fibroblasts infected by human cytomegalovirus. Eur J Med Res. 2013 Feb 1;18:3. PMID: 23369524.

O'Donnell EF, Kopparapu PR, Koch DC, et al. The aryl hydrocarbon receptor mediates leflunomide-induced growth inhibition of melanoma cells. PLoS One. 2012;7(7):e40926. PMID: 22815870.

Bernhoff E, Tylden GD, Kjerpeseth LJ, et al. Leflunomide inhibition of BK virus replication in renal tubular epithelial cells. J Virol. 2010 Feb;84(4):2150-6. PMID: 19955306.

Pinto P, Dougados M. Leflunomide in clinical practice. Acta Reumatol Port. 2006 Jul-Sep;31(3):215-24. PMID: 17094333.

" Xn, Xi "UN number: 2811     Class: 6.1     Packing Group: III

Proper shipping name: Toxic solid, organic, n.o.s. (Leflunomide)"

LKT T1298 TDZD-8 5 mg 61.1 GSK-3β inhibitor. 4-Benzyl-2-methyl-1,2,4-thiadiazolidine-3,5-dione 327036-89-5 ≥98% 222.26 C10H10N2O2S CN1C(=O)N(C(=O)S1)CC2=CC=CC=C2 Protect from light. Packaged under inert gas. Ambient -20°C Soluble in DMSO (18mg/mL). "Jellestad L, Fink T, Pradarutti S, et al. Inhibition of glycogen synthase kinase (GSK)-3-β improves liver microcirculation and hepatocellular function after hemorrhagic shock. Eur J Pharmacol. 2014 Feb 5;724:175-84. PMID: 24389157.

Kwon YJ, Yoon CH, Lee SW, et al. Inhibition of glycogen synthase kinase-3β suppresses inflammatory responses in rheumatoid arthritis fibroblast-like synoviocytes and collagen-induced arthritis. Joint Bone Spine. 2013 Oct 28. [Epub ahead of print]. PMID: 24176738.

Willi R, Harmeier A, Giovanoli S, et al. Altered GSK3β signaling in an infection-based mouse model of developmental neuropsychiatric disease. Neuropharmacology. 2013 Oct;73:56-65. PMID: 23707483.

" Not dangerous goods.

LKT L1878 Letrozole 25 mg 104.3 Aromatase inhibitor. 4,4'-(1H-1,2,4-Triazol-1-ylmethylene)bisbenzonitrile Femara  112809-51-5 ≥98% 285.3 C17H11N5 C1=CC(=CC=C1C#N)C(C2=CC=C(C=C2)C#N)N3C=NC=N3 Ambient -20°C Soluble in dichloromethane, DMSO (100 mM). Slightly soluble in ethanol. practically insoluble in water.  Soluble in chloroform, methanol. "Lee VC, Gao J, Lee KF, et al. The effect of letrozole with misoprostol for medical termination of pregnancy on the expression of steroid receptors in the placenta. Hum Reprod. 2013 Nov;28(11):2912-9. PMID: 23980056.

Tomao F, Spinelli G, Vici P, et al. Current role and safety profile of aromatase inhibitors in early breast cancer. Expert Rev Anticancer Ther. 2011 Aug;11(8):1253-63. PMID: 21916579.

Yapura J, Mapletoft RJ, Pierson R, et al. A bovine model for examining the effects of an aromatase inhibitor on ovarian function in women. Fertil Steril. 2011 Aug;96(2):434-438.e3. PMID: 21696721.

" None Not dangerous goods.

LKT L1878 Letrozole 50 mg 173.3 Aromatase inhibitor. 4,4'-(1H-1,2,4-Triazol-1-ylmethylene)bisbenzonitrile Femara  112809-51-5 ≥98% 285.3 C17H11N5 C1=CC(=CC=C1C#N)C(C2=CC=C(C=C2)C#N)N3C=NC=N3 Ambient -20°C Soluble in dichloromethane, DMSO (100 mM). Slightly soluble in ethanol. practically insoluble in water.  Soluble in chloroform, methanol. "Lee VC, Gao J, Lee KF, et al. The effect of letrozole with misoprostol for medical termination of pregnancy on the expression of steroid receptors in the placenta. Hum Reprod. 2013 Nov;28(11):2912-9. PMID: 23980056.

Tomao F, Spinelli G, Vici P, et al. Current role and safety profile of aromatase inhibitors in early breast cancer. Expert Rev Anticancer Ther. 2011 Aug;11(8):1253-63. PMID: 21916579.

Yapura J, Mapletoft RJ, Pierson R, et al. A bovine model for examining the effects of an aromatase inhibitor on ovarian function in women. Fertil Steril. 2011 Aug;96(2):434-438.e3. PMID: 21696721.

" None Not dangerous goods.

LKT L1878 Letrozole 100 mg 288.8 Aromatase inhibitor. 4,4'-(1H-1,2,4-Triazol-1-ylmethylene)bisbenzonitrile Femara  112809-51-5 ≥98% 285.3 C17H11N5 C1=CC(=CC=C1C#N)C(C2=CC=C(C=C2)C#N)N3C=NC=N3 Ambient -20°C Soluble in dichloromethane, DMSO (100 mM). Slightly soluble in ethanol. practically insoluble in water.  Soluble in chloroform, methanol. "Lee VC, Gao J, Lee KF, et al. The effect of letrozole with misoprostol for medical termination of pregnancy on the expression of steroid receptors in the placenta. Hum Reprod. 2013 Nov;28(11):2912-9. PMID: 23980056.

Tomao F, Spinelli G, Vici P, et al. Current role and safety profile of aromatase inhibitors in early breast cancer. Expert Rev Anticancer Ther. 2011 Aug;11(8):1253-63. PMID: 21916579.

Yapura J, Mapletoft RJ, Pierson R, et al. A bovine model for examining the effects of an aromatase inhibitor on ovarian function in women. Fertil Steril. 2011 Aug;96(2):434-438.e3. PMID: 21696721.

" None Not dangerous goods.

LKT T0299 Tazobactam Sodium 100 mg 96.2 β-lactamase inhibitor. "(2S,3S,5R)-3-Methyl-7-oxo-3-(1H-1,2,3-triazol-1-

ylmethyl)-4-thia-1-azabicyclo[3.2.0]heptane-2- carboxylic acid 4,4-dioxide sodium salt" YTR-830; CL-307579 89785-84-2 ≥93% 322.28 C10H11N4NaO5S CC1(C(N2C(S1(=O)=O)CC2=O)C(=O)[O-])CN3C=CN=N3.[Na+] Ambient Ambient +135°~+150° Soluble in water. "Zhanel GG, Chung P, Adam H, et al. Ceftolozane/tazobactam: a novel cephalosporin/β-lactamase inhibitor combination with activity against multidrug-resistant gram-negative bacilli. Drugs. 2014 Jan;74(1):31-51. PMID: 24352909.

Frase H, Smith CA, Toth M, et al. Identification of products of inhibition of GES-2 beta-lactamase by tazobactam by x-ray crystallography and spectrometry. J Biol Chem. 2011 Apr 22;286(16):14396-409. PMID: 21345789.

Drawz SM, Bonomo RA. Three decades of beta-lactamase inhibitors. Clin Microbiol Rev. 2010 Jan;23(1):160-201. PMID: 20065329.

" None Not dangerous goods.

LKT T0299 Tazobactam Sodium 500 mg 362.7 β-lactamase inhibitor. "(2S,3S,5R)-3-Methyl-7-oxo-3-(1H-1,2,3-triazol-1-

ylmethyl)-4-thia-1-azabicyclo[3.2.0]heptane-2- carboxylic acid 4,4-dioxide sodium salt" YTR-830; CL-307579 89785-84-2 ≥93% 322.28 C10H11N4NaO5S CC1(C(N2C(S1(=O)=O)CC2=O)C(=O)[O-])CN3C=CN=N3.[Na+] Ambient Ambient +135°~+150° Soluble in water. "Zhanel GG, Chung P, Adam H, et al. Ceftolozane/tazobactam: a novel cephalosporin/β-lactamase inhibitor combination with activity against multidrug-resistant gram-negative bacilli. Drugs. 2014 Jan;74(1):31-51. PMID: 24352909.

Frase H, Smith CA, Toth M, et al. Identification of products of inhibition of GES-2 beta-lactamase by tazobactam by x-ray crystallography and spectrometry. J Biol Chem. 2011 Apr 22;286(16):14396-409. PMID: 21345789.

Drawz SM, Bonomo RA. Three decades of beta-lactamase inhibitors. Clin Microbiol Rev. 2010 Jan;23(1):160-201. PMID: 20065329.

" None Not dangerous goods.

LKT T0299 Tazobactam Sodium 1 g 658.8 β-lactamase inhibitor. "(2S,3S,5R)-3-Methyl-7-oxo-3-(1H-1,2,3-triazol-1-

ylmethyl)-4-thia-1-azabicyclo[3.2.0]heptane-2- carboxylic acid 4,4-dioxide sodium salt" YTR-830; CL-307579 89785-84-2 ≥93% 322.28 C10H11N4NaO5S CC1(C(N2C(S1(=O)=O)CC2=O)C(=O)[O-])CN3C=CN=N3.[Na+] Ambient Ambient +135°~+150° Soluble in water. "Zhanel GG, Chung P, Adam H, et al. Ceftolozane/tazobactam: a novel cephalosporin/β-lactamase inhibitor combination with activity against multidrug-resistant gram-negative bacilli. Drugs. 2014 Jan;74(1):31-51. PMID: 24352909.

Frase H, Smith CA, Toth M, et al. Identification of products of inhibition of GES-2 beta-lactamase by tazobactam by x-ray crystallography and spectrometry. J Biol Chem. 2011 Apr 22;286(16):14396-409. PMID: 21345789.

Drawz SM, Bonomo RA. Three decades of beta-lactamase inhibitors. Clin Microbiol Rev. 2010 Jan;23(1):160-201. PMID: 20065329.

" None Not dangerous goods.

LKT L1881 Leuprolide Acetate 1 mg 96.7 GnRH analog; GnRH1 agonist. Leuprorelin; des-Gly10-[D-Leu6]-LH-RH ethylamide 74381-53-6 ≥98% 1269.65 C59H84N16O12 C2H4O2 CCNC(=O)C1CCCN1C(=O)C(CCCN=C(N)N)NC(=O)C(CC(C)C)NC(=O)C(CC(C)C)NC(=O)C(CC2=CC=C(C=C2)O)NC(=O)C(CO)NC(=O)C(CC3=CNC4=CC=CC=C43)NC(=O)C(CC5=CN=CN5)NC(=O)C6CCC(=O)N6.CC(=O)O Ambient -20°C Soluble  in water "Ko YH, Ha YR, Kim JW, et al. Silencing of the GnRH type 1 receptor blocks the antiproliferative effect of the GnRH agonist, leuprolide, on the androgen-independent prostate cancer cell line DU145. J Int Med Res. 2011;39(3):729-39. PMID: 21819703.

Tesone M, Bilotas M, Barañao RI, et al. The role of GnRH analogues in endometriosis-associated apoptosis and angiogenesis. Gynecol Obstet Invest. 2008;66 Suppl 1:10-8. PMID: 18936547.

Umathe SN, Dixit PV, Wanjari MM, et al. Leuprolide--a GnRH agonist--prevents restraint stress-induced immunosuppression via sex steroid-independent peripheral mechanism in mice. Int Immunopharmacol. 2008 Jan;8(1):71-9. PMID: 18068102.

Nagai N, Oshita T, Mukai K, et al. GnRH agonist inhibits human telomerase reverse transcriptase mRNA expression in endometrial cancer cells. Int J Mol Med. 2002 Nov;10(5):593-7. PMID: 12373298.

" Not dangerous goods.

LKT L1881 Leuprolide Acetate 5 mg 335.4 GnRH analog; GnRH1 agonist. Leuprorelin; des-Gly10-[D-Leu6]-LH-RH ethylamide 74381-53-6 ≥98% 1269.65 C59H84N16O12 C2H4O2 CCNC(=O)C1CCCN1C(=O)C(CCCN=C(N)N)NC(=O)C(CC(C)C)NC(=O)C(CC(C)C)NC(=O)C(CC2=CC=C(C=C2)O)NC(=O)C(CO)NC(=O)C(CC3=CNC4=CC=CC=C43)NC(=O)C(CC5=CN=CN5)NC(=O)C6CCC(=O)N6.CC(=O)O Ambient -20°C Soluble  in water "Ko YH, Ha YR, Kim JW, et al. Silencing of the GnRH type 1 receptor blocks the antiproliferative effect of the GnRH agonist, leuprolide, on the androgen-independent prostate cancer cell line DU145. J Int Med Res. 2011;39(3):729-39. PMID: 21819703.

Tesone M, Bilotas M, Barañao RI, et al. The role of GnRH analogues in endometriosis-associated apoptosis and angiogenesis. Gynecol Obstet Invest. 2008;66 Suppl 1:10-8. PMID: 18936547.

Umathe SN, Dixit PV, Wanjari MM, et al. Leuprolide--a GnRH agonist--prevents restraint stress-induced immunosuppression via sex steroid-independent peripheral mechanism in mice. Int Immunopharmacol. 2008 Jan;8(1):71-9. PMID: 18068102.

Nagai N, Oshita T, Mukai K, et al. GnRH agonist inhibits human telomerase reverse transcriptase mRNA expression in endometrial cancer cells. Int J Mol Med. 2002 Nov;10(5):593-7. PMID: 12373298.

" Not dangerous goods.

LKT T0298 Tazobactam 100 mg 61.1 β-lactamase inhibitor. "(2S,3S,5R)-3-Methyl-7-oxo-3-(1H-1,2,3-triazol-1-

ylmethyl)-4-thia-1-azabicyclo[3.2.0]heptane-2- carboxylic acid 4,4-dioxide " YTR-830H; CL-298741 89786-04-9 ≥98% 300.29 C10H12N4O5S CC1(C(N2C(S1(=O)=O)CC2=O)C(=O)O)CN3C=CN=N3 Ambient Ambient water, methanol "Zhanel GG, Chung P, Adam H, et al. Ceftolozane/tazobactam: a novel cephalosporin/β-lactamase inhibitor combination with activity against multidrug-resistant gram-negative bacilli. Drugs. 2014 Jan;74(1):31-51. PMID: 24352909.

Frase H, Smith CA, Toth M, et al. Identification of products of inhibition of GES-2 beta-lactamase by tazobactam by x-ray crystallography and spectrometry. J Biol Chem. 2011 Apr 22;286(16):14396-409. PMID: 21345789.

Drawz SM, Bonomo RA. Three decades of beta-lactamase inhibitors. Clin Microbiol Rev. 2010 Jan;23(1):160-201. PMID: 20065329.

" Xi Not dangerous goods.

LKT T0298 Tazobactam 500 mg 197.1 β-lactamase inhibitor. "(2S,3S,5R)-3-Methyl-7-oxo-3-(1H-1,2,3-triazol-1-

ylmethyl)-4-thia-1-azabicyclo[3.2.0]heptane-2- carboxylic acid 4,4-dioxide " YTR-830H; CL-298741 89786-04-9 ≥98% 300.29 C10H12N4O5S CC1(C(N2C(S1(=O)=O)CC2=O)C(=O)O)CN3C=CN=N3 Ambient Ambient water, methanol "Zhanel GG, Chung P, Adam H, et al. Ceftolozane/tazobactam: a novel cephalosporin/β-lactamase inhibitor combination with activity against multidrug-resistant gram-negative bacilli. Drugs. 2014 Jan;74(1):31-51. PMID: 24352909.

Frase H, Smith CA, Toth M, et al. Identification of products of inhibition of GES-2 beta-lactamase by tazobactam by x-ray crystallography and spectrometry. J Biol Chem. 2011 Apr 22;286(16):14396-409. PMID: 21345789.

Drawz SM, Bonomo RA. Three decades of beta-lactamase inhibitors. Clin Microbiol Rev. 2010 Jan;23(1):160-201. PMID: 20065329.

" Xi Not dangerous goods.

LKT T0298 Tazobactam 1 g 339.8 β-lactamase inhibitor. "(2S,3S,5R)-3-Methyl-7-oxo-3-(1H-1,2,3-triazol-1-

ylmethyl)-4-thia-1-azabicyclo[3.2.0]heptane-2- carboxylic acid 4,4-dioxide " YTR-830H; CL-298741 89786-04-9 ≥98% 300.29 C10H12N4O5S CC1(C(N2C(S1(=O)=O)CC2=O)C(=O)O)CN3C=CN=N3 Ambient Ambient water, methanol "Zhanel GG, Chung P, Adam H, et al. Ceftolozane/tazobactam: a novel cephalosporin/β-lactamase inhibitor combination with activity against multidrug-resistant gram-negative bacilli. Drugs. 2014 Jan;74(1):31-51. PMID: 24352909.

Frase H, Smith CA, Toth M, et al. Identification of products of inhibition of GES-2 beta-lactamase by tazobactam by x-ray crystallography and spectrometry. J Biol Chem. 2011 Apr 22;286(16):14396-409. PMID: 21345789.

Drawz SM, Bonomo RA. Three decades of beta-lactamase inhibitors. Clin Microbiol Rev. 2010 Jan;23(1):160-201. PMID: 20065329.

" Xi Not dangerous goods.

LKT L1884 Levosimendan 100 mg 95.1 Ca2+ sensitizer; ATP-sensitive K+ channel activator, troponin C stabilizer, PDE inhibitor. "Mesoxalonitrile (-)-(p((R)-1,4,5,6-tetrahydro-4-methyl-6-

oxo-3-pyridazinyl)phenyl)hydrazone" Simdax 141505-33-1 ≥98% 280.28 C14H12N6O CC1CC(=O)NN=C1C2=CC=C(C=C2)NN=C(C#N)C#N Store in a cool, dry place. Protect from direct light. Ambient 4°C Insoluble in water (0.04 mg/ml), soluble in DMSO (>50 mg/ml). "Pathak A, Lebrin M, Vaccaro A, et al. Pharmacology of levosimendan: inotropic, vasodilatory and cardioprotective effects. J Clin Pharm Ther. 2013 Oct;38(5):341-9. PMID: 23594161.

Malmberg M, Vähäsilta T, Saraste A, et al. Intracoronary Levosimendan during Ischemia Prevents Myocardial Apoptosis. Front Physiol. 2012 Feb 14;3:17. PMID: 22347864.

Papp Z, Édes I, Fruhwald S, et al. Levosimendan: molecular mechanisms and clinical implications: consensus of experts on the mechanisms of action of levosimendan. Int J Cardiol. 2012 Aug 23;159(2):82-7. PMID: 21784540.

Milligan DJ, Fields AM. Levosimendan: calcium sensitizer and inodilator. Anesthesiol Clin. 2010 Dec;28(4):753-60. PMID: 21074750.

" Not dangerous goods.