LKT Labs NA100NSAIDs 1 kit

LKT Labs 是一家专注于防癌抗癌特殊化学品研究和开发的公司。主要提供：癌症药物、药物发现试剂盒、天然产物、广泛的生命科学研究试剂、定制合成。
美国LKT Labs 是1988年在美国成立的，为全球提供先端的药物研发试剂、试剂盒、委托合成，并为药物生产企业提供原料，最近几年在农药、水产养殖业有很大程度的开发。在LKT Labs 可以找到在其他地方找不到的产品。

LKT Labs NA100 NSAIDs 1 kit

LKT Labs NA100 NSAIDs 1 kit

LKT M5675 Motilin, dog 1 mg 348 Endogenous peptide hormone; motilin agonist. 85490-53-5 ≥95% 2685.1 C120H194N36O34 CCC(C)C(C(=O)NC(CC1=CC=CC=C1)C(=O)NC(C(C)O)C(=O)NC(CC2=CNC=N2)C(=O)NC(CO)C(=O)NC(CCC(=O)O)C(=O)NC(CC(C)C)C(=O)NC(CCC(=O)N)C(=O)NC(CCCCN)C(=O)NC(C(C)CC)C(=O)NC(CCCNC(=N)N)C(=O)NC(CCC(=O)O)C(=O)NC(CCCCN)C(=O)NC(CCC(=O)O)C(=O)NC(CCCNC(=N)N)C(=O)NC(CC(=O)N)C(=O)NC(CCCCN)C(=O)NCC(=O)NC(CCC(=O)N)C(=O)O)NC(=O)C3CCCN3C(=O)C(C(C)C)NC(=O)C(CC4=CC=CC=C4)N Ambient -20°C "Sanger GJ, Wang Y, Hobson A, et al. Motilin: towards a new understanding of the gastrointestinal neuropharmacology and therapeutic use of motilin receptor agonists. Br J Pharmacol. 2013 Dec;170(7):1323-32. PMID: 23189978.

Feng B, Liu JC, Zhang J, et al. Anxiolytic actions of motilin in the basolateral amygdala. Mol Neurobiol. 2013 Jun;47(3):892-902. PMID: 23307330.

Miegueu P, Cianflone K, Richard D, et al. Motilin stimulates preadipocyte proliferation and differentiation and adipocyte lipid storage. Am J Physiol Endocrinol Metab. 2011 Nov;301(5):E758-66. PMID: 21771971.

Piche T, Galmiche JP. Pharmacological targets in gastro-oesophageal reflux disease. Basic Clin Pharmacol Toxicol. 2005 Dec;97(6):333-41. PMID: 16364047.

" Not dangerous goods.

LKT M5675 Motilin, dog 2.5 mg 612.4 Endogenous peptide hormone; motilin agonist. 85490-53-5 ≥95% 2685.1 C120H194N36O34 CCC(C)C(C(=O)NC(CC1=CC=CC=C1)C(=O)NC(C(C)O)C(=O)NC(CC2=CNC=N2)C(=O)NC(CO)C(=O)NC(CCC(=O)O)C(=O)NC(CC(C)C)C(=O)NC(CCC(=O)N)C(=O)NC(CCCCN)C(=O)NC(C(C)CC)C(=O)NC(CCCNC(=N)N)C(=O)NC(CCC(=O)O)C(=O)NC(CCCCN)C(=O)NC(CCC(=O)O)C(=O)NC(CCCNC(=N)N)C(=O)NC(CC(=O)N)C(=O)NC(CCCCN)C(=O)NCC(=O)NC(CCC(=O)N)C(=O)O)NC(=O)C3CCCN3C(=O)C(C(C)C)NC(=O)C(CC4=CC=CC=C4)N Ambient -20°C "Sanger GJ, Wang Y, Hobson A, et al. Motilin: towards a new understanding of the gastrointestinal neuropharmacology and therapeutic use of motilin receptor agonists. Br J Pharmacol. 2013 Dec;170(7):1323-32. PMID: 23189978.

Feng B, Liu JC, Zhang J, et al. Anxiolytic actions of motilin in the basolateral amygdala. Mol Neurobiol. 2013 Jun;47(3):892-902. PMID: 23307330.

Miegueu P, Cianflone K, Richard D, et al. Motilin stimulates preadipocyte proliferation and differentiation and adipocyte lipid storage. Am J Physiol Endocrinol Metab. 2011 Nov;301(5):E758-66. PMID: 21771971.

Piche T, Galmiche JP. Pharmacological targets in gastro-oesophageal reflux disease. Basic Clin Pharmacol Toxicol. 2005 Dec;97(6):333-41. PMID: 16364047.

" Not dangerous goods.

LKT M5727 Moguisteine 100 mg 47.6 Potential ATP-sensitive K+ channel blocker, potential irritant receptor antagonist. +/-)-2-(2-Methoxyphenoxy)-methyl-3-ethoxycarbonylacetyl-1,3-thiazolidine; (R,S)-2-(2-Methoxyphenoxy)-methyl-3-ethoxycarbonyl-acetyl-1,3 thiazolidine 119637-67-1 ≥98% 339.41 C16H21NO5S CCOC(=O)CC(=O)N1CCSC1COC2=CC=CC=C2OC Ambient Ambient "Luo YL, Li PB, Zhang CC, et al. Effects of four antitussives on airway neurogenic inflammation in a guinea pig model of chronic cough induced by cigarette smoke exposure. Inflamm Res. 2013 Dec;62(12):1053-61. PMID: 24085318.

Morita K, Onodera K, Kamei J. Inhaled pinacidil, an ATP-sensitive K+ channel opener, and moguisteine have potent antitussive effects in guinea pigs. Jpn J Pharmacol. 2002 Jun;89(2):171-5. PMID: 12120760.

Sant'Ambrogio G, Sant'Ambrogio FB. Action of moguisteine on the activity of tracheobronchial rapidly adapting receptors in the dog. Eur Respir J. 1998 Feb;11(2):339-44. PMID: 9551735.

" Not dangerous goods.

LKT M5727 Moguisteine 250 mg 95.1 Potential ATP-sensitive K+ channel blocker, potential irritant receptor antagonist. +/-)-2-(2-Methoxyphenoxy)-methyl-3-ethoxycarbonylacetyl-1,3-thiazolidine; (R,S)-2-(2-Methoxyphenoxy)-methyl-3-ethoxycarbonyl-acetyl-1,3 thiazolidine 119637-67-1 ≥98% 339.41 C16H21NO5S CCOC(=O)CC(=O)N1CCSC1COC2=CC=CC=C2OC Ambient Ambient "Luo YL, Li PB, Zhang CC, et al. Effects of four antitussives on airway neurogenic inflammation in a guinea pig model of chronic cough induced by cigarette smoke exposure. Inflamm Res. 2013 Dec;62(12):1053-61. PMID: 24085318.

Morita K, Onodera K, Kamei J. Inhaled pinacidil, an ATP-sensitive K+ channel opener, and moguisteine have potent antitussive effects in guinea pigs. Jpn J Pharmacol. 2002 Jun;89(2):171-5. PMID: 12120760.

Sant'Ambrogio G, Sant'Ambrogio FB. Action of moguisteine on the activity of tracheobronchial rapidly adapting receptors in the dog. Eur Respir J. 1998 Feb;11(2):339-44. PMID: 9551735.

" Not dangerous goods.

LKT M5727 Moguisteine 1 g 285.4 Potential ATP-sensitive K+ channel blocker, potential irritant receptor antagonist. +/-)-2-(2-Methoxyphenoxy)-methyl-3-ethoxycarbonylacetyl-1,3-thiazolidine; (R,S)-2-(2-Methoxyphenoxy)-methyl-3-ethoxycarbonyl-acetyl-1,3 thiazolidine 119637-67-1 ≥98% 339.41 C16H21NO5S CCOC(=O)CC(=O)N1CCSC1COC2=CC=CC=C2OC Ambient Ambient "Luo YL, Li PB, Zhang CC, et al. Effects of four antitussives on airway neurogenic inflammation in a guinea pig model of chronic cough induced by cigarette smoke exposure. Inflamm Res. 2013 Dec;62(12):1053-61. PMID: 24085318.

Morita K, Onodera K, Kamei J. Inhaled pinacidil, an ATP-sensitive K+ channel opener, and moguisteine have potent antitussive effects in guinea pigs. Jpn J Pharmacol. 2002 Jun;89(2):171-5. PMID: 12120760.

Sant'Ambrogio G, Sant'Ambrogio FB. Action of moguisteine on the activity of tracheobronchial rapidly adapting receptors in the dog. Eur Respir J. 1998 Feb;11(2):339-44. PMID: 9551735.

" Not dangerous goods.

LKT S1612 Sedanolide 100 mg 179.6 Phthalide found in celery seeds; COX-1, COX-2, topoisomerase I, topoisomerase II inhibitor. 3-Butyl-3α,4,5,6-tetrahydro-1(3H)-isobenzofuranone Neocnidilide 6415-59-4 ≥98% 194.13 C12H18O2 CCCCC1C2CCCC=C2C(=O)O1 Ambient -20°C Soluble in acetonitrile, ethanol, and methanol. "Tsukamoto T, Ishikawa Y, Miyazawa M. Larvicidal and adulticidal activity of alkylphthalide derivatives from rhizome of Cnidium officinale against Drosophila melanogaster. J Agric Food Chem. 2005 Jul 13;53(14):5549-53. PMID: 15998112.

Jiao XZ, Xie P, Zu LS, et al. Study of stereoselective synthesis of (+/-)-neocnidilide. J Asian Nat Prod Res. 2003 Sep;5(3):165-9. PMID: 12931848.

Momin RA, Nair MG. Antioxidant, cyclooxygenase and topoisomerase inhibitory compounds from Apium graveolens Linn. seeds. Phytomedicine. 2002 May;9(4):312-8. PMID: 12120812.

Momin RA, Nair MG. Mosquitocidal, nematicidal, and antifungal compounds from Apium graveolens L. seeds. J Agric Food Chem. 2001 Jan;49(1):142-5. PMID: 11305251.

" Not dangerous goods.

LKT S1612 Sedanolide 500 mg 546 Phthalide found in celery seeds; COX-1, COX-2, topoisomerase I, topoisomerase II inhibitor. 3-Butyl-3α,4,5,6-tetrahydro-1(3H)-isobenzofuranone Neocnidilide 6415-59-4 ≥98% 194.13 C12H18O2 CCCCC1C2CCCC=C2C(=O)O1 Ambient -20°C Soluble in acetonitrile, ethanol, and methanol. "Tsukamoto T, Ishikawa Y, Miyazawa M. Larvicidal and adulticidal activity of alkylphthalide derivatives from rhizome of Cnidium officinale against Drosophila melanogaster. J Agric Food Chem. 2005 Jul 13;53(14):5549-53. PMID: 15998112.

Jiao XZ, Xie P, Zu LS, et al. Study of stereoselective synthesis of (+/-)-neocnidilide. J Asian Nat Prod Res. 2003 Sep;5(3):165-9. PMID: 12931848.

Momin RA, Nair MG. Antioxidant, cyclooxygenase and topoisomerase inhibitory compounds from Apium graveolens Linn. seeds. Phytomedicine. 2002 May;9(4):312-8. PMID: 12120812.

Momin RA, Nair MG. Mosquitocidal, nematicidal, and antifungal compounds from Apium graveolens L. seeds. J Agric Food Chem. 2001 Jan;49(1):142-5. PMID: 11305251.

" Not dangerous goods.

LKT S1612 Sedanolide 1 g 952.5 Phthalide found in celery seeds; COX-1, COX-2, topoisomerase I, topoisomerase II inhibitor. 3-Butyl-3α,4,5,6-tetrahydro-1(3H)-isobenzofuranone Neocnidilide 6415-59-4 ≥98% 194.13 C12H18O2 CCCCC1C2CCCC=C2C(=O)O1 Ambient -20°C Soluble in acetonitrile, ethanol, and methanol. "Tsukamoto T, Ishikawa Y, Miyazawa M. Larvicidal and adulticidal activity of alkylphthalide derivatives from rhizome of Cnidium officinale against Drosophila melanogaster. J Agric Food Chem. 2005 Jul 13;53(14):5549-53. PMID: 15998112.

Jiao XZ, Xie P, Zu LS, et al. Study of stereoselective synthesis of (+/-)-neocnidilide. J Asian Nat Prod Res. 2003 Sep;5(3):165-9. PMID: 12931848.

Momin RA, Nair MG. Antioxidant, cyclooxygenase and topoisomerase inhibitory compounds from Apium graveolens Linn. seeds. Phytomedicine. 2002 May;9(4):312-8. PMID: 12120812.

Momin RA, Nair MG. Mosquitocidal, nematicidal, and antifungal compounds from Apium graveolens L. seeds. J Agric Food Chem. 2001 Jan;49(1):142-5. PMID: 11305251.

" Not dangerous goods.

LKT M5746 Molsidomine 500 mg 54.4 NO donor; annexin A2 inhibitor. N-(Ethoxycarbonyl)-3-(4-morpholinyl)sydnone imine Corvaton; Corvasal; Molsidolat; Morial; Motazominn 25717-80-0 ≥98% 242.23 C9H14N4O4 CCOC(=NC1=C[N+](=NO1)N2CCOCC2)[O-] Ambient Ambient Soluble in chloroform, methanol, ethanol, or ethyl acetate. Slightly soluble in water, acetone or benzene. "Harnek J, Zoucas E, de Sá VP, et al. Intimal hyperplasia in balloon dilated coronary arteries is reduced by local delivery of the NO donor, SIN-1 via a cGMP-dependent pathway. BMC Cardiovasc Disord. 2011 Jun 11;11:30. PMID: 21663688.

Won KJ, Lee P, Jung SH, et al. 3-morpholinosydnonimine participates in the attenuation of neointima formation via inhibition of annexin A2-mediated vascular smooth muscle cell migration. Proteomics. 2011 Jan;11(2):193-201. PMID: 21204247.

Cardoso MH, Morganti RP, Lilla S, et al. The role of superoxide anion in the inhibitory effect of SIN-1 in thrombin-activated human platelet adhesion. Eur J Pharmacol. 2010 Feb 10;627(1-3):229-34. PMID: 19895807.

" Xn Not dangerous goods.

LKT M5746 Molsidomine 1 g 95.1 NO donor; annexin A2 inhibitor. N-(Ethoxycarbonyl)-3-(4-morpholinyl)sydnone imine Corvaton; Corvasal; Molsidolat; Morial; Motazominn 25717-80-0 ≥98% 242.23 C9H14N4O4 CCOC(=NC1=C[N+](=NO1)N2CCOCC2)[O-] Ambient Ambient Soluble in chloroform, methanol, ethanol, or ethyl acetate. Slightly soluble in water, acetone or benzene. "Harnek J, Zoucas E, de Sá VP, et al. Intimal hyperplasia in balloon dilated coronary arteries is reduced by local delivery of the NO donor, SIN-1 via a cGMP-dependent pathway. BMC Cardiovasc Disord. 2011 Jun 11;11:30. PMID: 21663688.

Won KJ, Lee P, Jung SH, et al. 3-morpholinosydnonimine participates in the attenuation of neointima formation via inhibition of annexin A2-mediated vascular smooth muscle cell migration. Proteomics. 2011 Jan;11(2):193-201. PMID: 21204247.

Cardoso MH, Morganti RP, Lilla S, et al. The role of superoxide anion in the inhibitory effect of SIN-1 in thrombin-activated human platelet adhesion. Eur J Pharmacol. 2010 Feb 10;627(1-3):229-34. PMID: 19895807.

" Xn Not dangerous goods.

LKT M5752 Monastrol 1 mg 151.7 Pyrimidine derivative; kinesin Eg5 inhibitor. 1,2,3,4-Tetra- hydro-4-(3-Hydroxyphenyl)- 6-methyl-2-thioxo-5-pyrimidinecarboxylic acid ethyl ester 254753-54-3 ≥95% 292.35 C14H16N2O3S CCOC(=O)C1=C(NC(=S)NC1C2=CC(=CC=C2)O)C Protect from light. Ambient 4°C Soluble in DMSO (100mg/mL). "Chin GM, Herbst R. Induction of apoptosis by monastrol, an inhibitor of the mitotic kinesin Eg5, is independent of the spindle checkpoint. Mol Cancer Ther. 2006 Oct;5(10):2580-91. PMID: 17041103.

Maliga Z, Mitchison TJ. Small-molecule and mutational analysis of allosteric Eg5 inhibition by monastrol. BMC Chem Biol. 2006 Feb 27;6:2. PMID: 16504166.

Yoon SY, Choi JE, Huh JW, et al. Monastrol, a selective inhibitor of the mitotic kinesin Eg5, induces a distinctive growth profile of dendrites and axons in primary cortical neuron cultures. Cell Motil Cytoskeleton. 2005 Apr;60(4):181-90. PMID: 15751098.

Maliga Z, Kapoor TM, Mitchison TJ. Evidence that monastrol is an allosteric inhibitor of the mitotic kinesin Eg5. Chem Biol. 2002 Sep;9(9):989-96. PMID: 12323373.

" Not dangerous goods.

LKT M5752 Monastrol 5 mg 364 Pyrimidine derivative; kinesin Eg5 inhibitor. 1,2,3,4-Tetra- hydro-4-(3-Hydroxyphenyl)- 6-methyl-2-thioxo-5-pyrimidinecarboxylic acid ethyl ester 254753-54-3 ≥95% 292.35 C14H16N2O3S CCOC(=O)C1=C(NC(=S)NC1C2=CC(=CC=C2)O)C Protect from light. Ambient 4°C Soluble in DMSO (100mg/mL). "Chin GM, Herbst R. Induction of apoptosis by monastrol, an inhibitor of the mitotic kinesin Eg5, is independent of the spindle checkpoint. Mol Cancer Ther. 2006 Oct;5(10):2580-91. PMID: 17041103.

Maliga Z, Mitchison TJ. Small-molecule and mutational analysis of allosteric Eg5 inhibition by monastrol. BMC Chem Biol. 2006 Feb 27;6:2. PMID: 16504166.

Yoon SY, Choi JE, Huh JW, et al. Monastrol, a selective inhibitor of the mitotic kinesin Eg5, induces a distinctive growth profile of dendrites and axons in primary cortical neuron cultures. Cell Motil Cytoskeleton. 2005 Apr;60(4):181-90. PMID: 15751098.

Maliga Z, Kapoor TM, Mitchison TJ. Evidence that monastrol is an allosteric inhibitor of the mitotic kinesin Eg5. Chem Biol. 2002 Sep;9(9):989-96. PMID: 12323373.

" Not dangerous goods.

LKT M5753 Monensin Sodium 500 mg 44.4 Polyether ionophore, autophagy inhibitor. 2-[5-Ethyltetrahydro-5-[tetrahydro-3-methyl-5-[tetra- hydro-6-hydroxy-6-(hydroxymethyl)-3,5-dimethyl- 2H-pyran-2-yl]-2-furyl]-2-furyl]-9-hydroxy-β- methoxy-α,γ,2,8-tetramethyl-1,6-dioxaspiro[4.5]- decane-7-butyric acid sodium salt Monensin sodium salt; Coban; Romemsin; Rumensin 22373-78-0 ≥98% 692.86 C36H61O11 Na CCC1(CCC(O1)C2(CCC3(O2)CC(C(C(O3)C(C)C(C(C)C(=O)[O-])OC)C)O)C)C4C(CC(O4)C5C(CC(C(O5)(CO)O)C)C)C.[Na+] Ambient 4°C Slightly soluble in water. Soluble in organic solvents. "Choi HS, Jeong EH, Lee TG, et al. Autophagy Inhibition with Monensin Enhances Cell Cycle Arrest and Apoptosis Induced by mTOR or Epidermal Growth Factor Receptor Inhibitors in Lung Cancer Cells. Tuberc Respir Dis (Seoul). 2013 Jul;75(1):9-17. PMID: 23946753.

Lavine MD, Arrizabalaga G. Analysis of monensin sensitivity in Toxoplasma gondii reveals autophagy as a mechanism for drug induced death. PLoS One. 2012;7(7):e42107. PMID: 22848721.

" T "UN number: 3462     Class:  6.1     Packing group:  II

Proper shipping name:  Toxins, extracted from living sources, solid, n.o.s. (Monensin monosodium salt)

Marine pollutant:  No.     Poison inhalation hazard:  No."

LKT M5753 Monensin Sodium 1 g 63.5 Polyether ionophore, autophagy inhibitor. 2-[5-Ethyltetrahydro-5-[tetrahydro-3-methyl-5-[tetra- hydro-6-hydroxy-6-(hydroxymethyl)-3,5-dimethyl- 2H-pyran-2-yl]-2-furyl]-2-furyl]-9-hydroxy-β- methoxy-α,γ,2,8-tetramethyl-1,6-dioxaspiro[4.5]- decane-7-butyric acid sodium salt Monensin sodium salt; Coban; Romemsin; Rumensin 22373-78-0 ≥98% 692.86 C36H61O11 Na CCC1(CCC(O1)C2(CCC3(O2)CC(C(C(O3)C(C)C(C(C)C(=O)[O-])OC)C)O)C)C4C(CC(O4)C5C(CC(C(O5)(CO)O)C)C)C.[Na+] Ambient 4°C Slightly soluble in water. Soluble in organic solvents. "Choi HS, Jeong EH, Lee TG, et al. Autophagy Inhibition with Monensin Enhances Cell Cycle Arrest and Apoptosis Induced by mTOR or Epidermal Growth Factor Receptor Inhibitors in Lung Cancer Cells. Tuberc Respir Dis (Seoul). 2013 Jul;75(1):9-17. PMID: 23946753.

Lavine MD, Arrizabalaga G. Analysis of monensin sensitivity in Toxoplasma gondii reveals autophagy as a mechanism for drug induced death. PLoS One. 2012;7(7):e42107. PMID: 22848721.

" T "UN number: 3462     Class:  6.1     Packing group:  II

Proper shipping name:  Toxins, extracted from living sources, solid, n.o.s. (Monensin monosodium salt)

Marine pollutant:  No.     Poison inhalation hazard:  No."

LKT M5753 Monensin Sodium 5 g 222.3 Polyether ionophore, autophagy inhibitor. 2-[5-Ethyltetrahydro-5-[tetrahydro-3-methyl-5-[tetra- hydro-6-hydroxy-6-(hydroxymethyl)-3,5-dimethyl- 2H-pyran-2-yl]-2-furyl]-2-furyl]-9-hydroxy-β- methoxy-α,γ,2,8-tetramethyl-1,6-dioxaspiro[4.5]- decane-7-butyric acid sodium salt Monensin sodium salt; Coban; Romemsin; Rumensin 22373-78-0 ≥98% 692.86 C36H61O11 Na CCC1(CCC(O1)C2(CCC3(O2)CC(C(C(O3)C(C)C(C(C)C(=O)[O-])OC)C)O)C)C4C(CC(O4)C5C(CC(C(O5)(CO)O)C)C)C.[Na+] Ambient 4°C Slightly soluble in water. Soluble in organic solvents. "Choi HS, Jeong EH, Lee TG, et al. Autophagy Inhibition with Monensin Enhances Cell Cycle Arrest and Apoptosis Induced by mTOR or Epidermal Growth Factor Receptor Inhibitors in Lung Cancer Cells. Tuberc Respir Dis (Seoul). 2013 Jul;75(1):9-17. PMID: 23946753.

Lavine MD, Arrizabalaga G. Analysis of monensin sensitivity in Toxoplasma gondii reveals autophagy as a mechanism for drug induced death. PLoS One. 2012;7(7):e42107. PMID: 22848721.

" T "UN number: 3462     Class:  6.1     Packing group:  II

Proper shipping name:  Toxins, extracted from living sources, solid, n.o.s. (Monensin monosodium salt)

Marine pollutant:  No.     Poison inhalation hazard:  No."

LKT M5756 Montelukast Sodium 10 mg 54.4 CysLT1 antagonist. "1-((((1R)-1-(3-((1E)-2-(7-chloro-2-

quinolinyl)ethenyl)phenyl)-3-(2-(1-hydroxy-1-

methylethyl)phenyl)propyl)thio)methyl)-Cyclopropaneacetic acid, monosodium salt" Singulair 151767-02-1 ≥98% 608.17 C35H35ClNO3S Na CC(C)(C1=CC=CC=C1CCC(C2=CC=CC(=C2)C=CC3=NC4=C(C=CC(=C4)Cl)C=C3)SCC5(CC5)CC(=O)[O-])O.[Na+] Hygroscopic. Ambient Ambient Soluble in ethanol, DMSO. "Zhou C, Shi X, Huang H, et al. Montelukast Attenuates Neuropathic Pain Through Inhibiting p38 Mitogen-Activated Protein Kinase and Nuclear Factor-Kappa B in a Rat Model of Chronic Constriction Injury. Anesth Analg. 2014 May;118(5):1090-6. PMID: 24686047.

Niimi A. Cough, asthma, and cysteinyl-leukotrienes. Pulm Pharmacol Ther. 2013 Oct;26(5):514-9. PMID: 23774534.

" None Not dangerous goods.

LKT M5756 Montelukast Sodium 25 mg 95.1 CysLT1 antagonist. "1-((((1R)-1-(3-((1E)-2-(7-chloro-2-

quinolinyl)ethenyl)phenyl)-3-(2-(1-hydroxy-1-

methylethyl)phenyl)propyl)thio)methyl)-Cyclopropaneacetic acid, monosodium salt" Singulair 151767-02-1 ≥98% 608.17 C35H35ClNO3S Na CC(C)(C1=CC=CC=C1CCC(C2=CC=CC(=C2)C=CC3=NC4=C(C=CC(=C4)Cl)C=C3)SCC5(CC5)CC(=O)[O-])O.[Na+] Hygroscopic. Ambient Ambient Soluble in ethanol, DMSO. "Zhou C, Shi X, Huang H, et al. Montelukast Attenuates Neuropathic Pain Through Inhibiting p38 Mitogen-Activated Protein Kinase and Nuclear Factor-Kappa B in a Rat Model of Chronic Constriction Injury. Anesth Analg. 2014 May;118(5):1090-6. PMID: 24686047.

Niimi A. Cough, asthma, and cysteinyl-leukotrienes. Pulm Pharmacol Ther. 2013 Oct;26(5):514-9. PMID: 23774534.

" None Not dangerous goods.

LKT M5756 Montelukast Sodium 100 mg 271.7 CysLT1 antagonist. "1-((((1R)-1-(3-((1E)-2-(7-chloro-2-

quinolinyl)ethenyl)phenyl)-3-(2-(1-hydroxy-1-

methylethyl)phenyl)propyl)thio)methyl)-Cyclopropaneacetic acid, monosodium salt" Singulair 151767-02-1 ≥98% 608.17 C35H35ClNO3S Na CC(C)(C1=CC=CC=C1CCC(C2=CC=CC(=C2)C=CC3=NC4=C(C=CC(=C4)Cl)C=C3)SCC5(CC5)CC(=O)[O-])O.[Na+] Hygroscopic. Ambient Ambient Soluble in ethanol, DMSO. "Zhou C, Shi X, Huang H, et al. Montelukast Attenuates Neuropathic Pain Through Inhibiting p38 Mitogen-Activated Protein Kinase and Nuclear Factor-Kappa B in a Rat Model of Chronic Constriction Injury. Anesth Analg. 2014 May;118(5):1090-6. PMID: 24686047.

Niimi A. Cough, asthma, and cysteinyl-leukotrienes. Pulm Pharmacol Ther. 2013 Oct;26(5):514-9. PMID: 23774534.

" None Not dangerous goods.

LKT S1607 Secretin, rat 0.5 mg 134.9 Endogenous peptide hormone, involved in feeding behavior; secretin agonist. 121028-49-7 ≥95% 3027.42 C129H216N42O42 CC(C)CC(C(=O)NC(C(C)C)C(=O)O)NC(=O)CNC(=O)C(CCC(=O)N)NC(=O)C(CC(C)C)NC(=O)C(CC(C)C)NC(=O)C(CCCNC(=N)N)NC(=O)C(CCC(=O)N)NC(=O)C(CC(C)C)NC(=O)C(CCCNC(=N)N)NC(=O)C(C)NC(=O)C(CO)NC(=O)C(CC(=O)O)NC(=O)C(CCCNC(=N)N)NC(=O)C(CC(C)C)NC(=O)C(CCCNC(=N)N)NC(=O)C(CO)NC(=O)C(CC(C)C)NC(=O)C(CCC(=O)O)NC(=O)C(CO)NC(=O)C(C(C)O)NC(=O)C(CC1=CC=CC=C1)NC(=O)C(C(C)O)NC(=O)CNC(=O)C(CC(=O)O)NC(=O)C(CO)NC(=O)C(CC2=NC=CN2)N Ambient -20°C "Sekar R, Chow BK. Lipolytic actions of secretin in mouse adipocytes. J Lipid Res. 2014 Feb;55(2):190-200. PMID: 24273196.

Miegueu P, Cianflone K, Richard D, et al. Effect of secretin on preadipocyte, differentiating and mature adipocyte functions. Int J Obes (Lond). 2013 Mar;37(3):366-74. PMID: 22565418.

Heinzlmann A, Kiss G, Tóth ZE, et al. Intranasal application of secretin, similarly to intracerebroventricular administration, influences the motor behavior of mice probably through specific receptors. J Mol Neurosci. 2012 Nov;48(3):558-64. PMID: 22752505.

Mahata M, Zhang K, Gayen JR, et al. Catecholamine biosynthesis and secretion: physiological and pharmacological effects of secretin. Cell Tissue Res. 2011 Jul;345(1):87-102. PMID: 21597914.

" Not dangerous goods.

LKT S1607 Secretin, rat 1 mg 228 Endogenous peptide hormone, involved in feeding behavior; secretin agonist. 121028-49-7 ≥95% 3027.42 C129H216N42O42 CC(C)CC(C(=O)NC(C(C)C)C(=O)O)NC(=O)CNC(=O)C(CCC(=O)N)NC(=O)C(CC(C)C)NC(=O)C(CC(C)C)NC(=O)C(CCCNC(=N)N)NC(=O)C(CCC(=O)N)NC(=O)C(CC(C)C)NC(=O)C(CCCNC(=N)N)NC(=O)C(C)NC(=O)C(CO)NC(=O)C(CC(=O)O)NC(=O)C(CCCNC(=N)N)NC(=O)C(CC(C)C)NC(=O)C(CCCNC(=N)N)NC(=O)C(CO)NC(=O)C(CC(C)C)NC(=O)C(CCC(=O)O)NC(=O)C(CO)NC(=O)C(C(C)O)NC(=O)C(CC1=CC=CC=C1)NC(=O)C(C(C)O)NC(=O)CNC(=O)C(CC(=O)O)NC(=O)C(CO)NC(=O)C(CC2=NC=CN2)N Ambient -20°C "Sekar R, Chow BK. Lipolytic actions of secretin in mouse adipocytes. J Lipid Res. 2014 Feb;55(2):190-200. PMID: 24273196.

Miegueu P, Cianflone K, Richard D, et al. Effect of secretin on preadipocyte, differentiating and mature adipocyte functions. Int J Obes (Lond). 2013 Mar;37(3):366-74. PMID: 22565418.

Heinzlmann A, Kiss G, Tóth ZE, et al. Intranasal application of secretin, similarly to intracerebroventricular administration, influences the motor behavior of mice probably through specific receptors. J Mol Neurosci. 2012 Nov;48(3):558-64. PMID: 22752505.

Mahata M, Zhang K, Gayen JR, et al. Catecholamine biosynthesis and secretion: physiological and pharmacological effects of secretin. Cell Tissue Res. 2011 Jul;345(1):87-102. PMID: 21597914.

" Not dangerous goods.

LKT S1607 Secretin, rat 2.5 mg 401.9 Endogenous peptide hormone, involved in feeding behavior; secretin agonist. 121028-49-7 ≥95% 3027.42 C129H216N42O42 CC(C)CC(C(=O)NC(C(C)C)C(=O)O)NC(=O)CNC(=O)C(CCC(=O)N)NC(=O)C(CC(C)C)NC(=O)C(CC(C)C)NC(=O)C(CCCNC(=N)N)NC(=O)C(CCC(=O)N)NC(=O)C(CC(C)C)NC(=O)C(CCCNC(=N)N)NC(=O)C(C)NC(=O)C(CO)NC(=O)C(CC(=O)O)NC(=O)C(CCCNC(=N)N)NC(=O)C(CC(C)C)NC(=O)C(CCCNC(=N)N)NC(=O)C(CO)NC(=O)C(CC(C)C)NC(=O)C(CCC(=O)O)NC(=O)C(CO)NC(=O)C(C(C)O)NC(=O)C(CC1=CC=CC=C1)NC(=O)C(C(C)O)NC(=O)CNC(=O)C(CC(=O)O)NC(=O)C(CO)NC(=O)C(CC2=NC=CN2)N Ambient -20°C "Sekar R, Chow BK. Lipolytic actions of secretin in mouse adipocytes. J Lipid Res. 2014 Feb;55(2):190-200. PMID: 24273196.

Miegueu P, Cianflone K, Richard D, et al. Effect of secretin on preadipocyte, differentiating and mature adipocyte functions. Int J Obes (Lond). 2013 Mar;37(3):366-74. PMID: 22565418.

Heinzlmann A, Kiss G, Tóth ZE, et al. Intranasal application of secretin, similarly to intracerebroventricular administration, influences the motor behavior of mice probably through specific receptors. J Mol Neurosci. 2012 Nov;48(3):558-64. PMID: 22752505.

Mahata M, Zhang K, Gayen JR, et al. Catecholamine biosynthesis and secretion: physiological and pharmacological effects of secretin. Cell Tissue Res. 2011 Jul;345(1):87-102. PMID: 21597914.

" Not dangerous goods.

LKT S1606 Secretin, pig 5 mg 684.1 Endogenous peptide hormone, involved in water homeostasis and feeding behavior; SCTR agonist. SecreFlo 17034-35-4 ≥95% 3055.4 C130H220N44O41 CC(C)CC(C(=O)NC(C(C)C)C(=O)N)NC(=O)CNC(=O)C(CCC(=O)N)NC(=O)C(CC(C)C)NC(=O)C(CC(C)C)NC(=O)C(CCCNC(=N)N)NC(=O)C(CCC(=O)N)NC(=O)C(CC(C)C)NC(=O)C(CCCNC(=N)N)NC(=O)C(C)NC(=O)C(CO)NC(=O)C(CC(=O)O)NC(=O)C(CCCNC(=N)N)NC(=O)C(CC(C)C)NC(=O)C(CCCNC(=N)N)NC(=O)C(CO)NC(=O)C(CC(C)C)NC(=O)C(CCC(=O)O)NC(=O)C(CO)NC(=O)C(C(C)O)NC(=O)C(CC1=CC=CC=C1)NC(=O)C(C(C)O)NC(=O)CNC(=O)C(CC(=O)O)NC(=O)C(CO)NC(=O)C(CC2=CN=CN2)N Ambient -20°C Soluble in water or saline. "Sekar R, Chow BK. Lipolytic actions of secretin in mouse adipocytes. J Lipid Res. 2014 Feb;55(2):190-200. PMID: 24273196.

Miegueu P, Cianflone K, Richard D, et al. Effect of secretin on preadipocyte, differentiating and mature adipocyte functions. Int J Obes (Lond). 2013 Mar;37(3):366-74. PMID: 22565418.

Heinzlmann A, Kiss G, Tóth ZE, et al. Intranasal application of secretin, similarly to intracerebroventricular administration, influences the motor behavior of mice probably through specific receptors. J Mol Neurosci. 2012 Nov;48(3):558-64. PMID: 22752505.

Mahata M, Zhang K, Gayen JR, et al. Catecholamine biosynthesis and secretion: physiological and pharmacological effects of secretin. Cell Tissue Res. 2011 Jul;345(1):87-102. PMID: 21597914.

" Not dangerous goods.

LKT S1606 Secretin, pig 10 mg 1164.1 Endogenous peptide hormone, involved in water homeostasis and feeding behavior; SCTR agonist. SecreFlo 17034-35-4 ≥95% 3055.4 C130H220N44O41 CC(C)CC(C(=O)NC(C(C)C)C(=O)N)NC(=O)CNC(=O)C(CCC(=O)N)NC(=O)C(CC(C)C)NC(=O)C(CC(C)C)NC(=O)C(CCCNC(=N)N)NC(=O)C(CCC(=O)N)NC(=O)C(CC(C)C)NC(=O)C(CCCNC(=N)N)NC(=O)C(C)NC(=O)C(CO)NC(=O)C(CC(=O)O)NC(=O)C(CCCNC(=N)N)NC(=O)C(CC(C)C)NC(=O)C(CCCNC(=N)N)NC(=O)C(CO)NC(=O)C(CC(C)C)NC(=O)C(CCC(=O)O)NC(=O)C(CO)NC(=O)C(C(C)O)NC(=O)C(CC1=CC=CC=C1)NC(=O)C(C(C)O)NC(=O)CNC(=O)C(CC(=O)O)NC(=O)C(CO)NC(=O)C(CC2=CN=CN2)N Ambient -20°C Soluble in water or saline. "Sekar R, Chow BK. Lipolytic actions of secretin in mouse adipocytes. J Lipid Res. 2014 Feb;55(2):190-200. PMID: 24273196.

Miegueu P, Cianflone K, Richard D, et al. Effect of secretin on preadipocyte, differentiating and mature adipocyte functions. Int J Obes (Lond). 2013 Mar;37(3):366-74. PMID: 22565418.

Heinzlmann A, Kiss G, Tóth ZE, et al. Intranasal application of secretin, similarly to intracerebroventricular administration, influences the motor behavior of mice probably through specific receptors. J Mol Neurosci. 2012 Nov;48(3):558-64. PMID: 22752505.

Mahata M, Zhang K, Gayen JR, et al. Catecholamine biosynthesis and secretion: physiological and pharmacological effects of secretin. Cell Tissue Res. 2011 Jul;345(1):87-102. PMID: 21597914.

" Not dangerous goods.

LKT S1606 Secretin, pig 25 mg 2052.2 Endogenous peptide hormone, involved in water homeostasis and feeding behavior; SCTR agonist. SecreFlo 17034-35-4 ≥95% 3055.4 C130H220N44O41 CC(C)CC(C(=O)NC(C(C)C)C(=O)N)NC(=O)CNC(=O)C(CCC(=O)N)NC(=O)C(CC(C)C)NC(=O)C(CC(C)C)NC(=O)C(CCCNC(=N)N)NC(=O)C(CCC(=O)N)NC(=O)C(CC(C)C)NC(=O)C(CCCNC(=N)N)NC(=O)C(C)NC(=O)C(CO)NC(=O)C(CC(=O)O)NC(=O)C(CCCNC(=N)N)NC(=O)C(CC(C)C)NC(=O)C(CCCNC(=N)N)NC(=O)C(CO)NC(=O)C(CC(C)C)NC(=O)C(CCC(=O)O)NC(=O)C(CO)NC(=O)C(C(C)O)NC(=O)C(CC1=CC=CC=C1)NC(=O)C(C(C)O)NC(=O)CNC(=O)C(CC(=O)O)NC(=O)C(CO)NC(=O)C(CC2=CN=CN2)N Ambient -20°C Soluble in water or saline. "Sekar R, Chow BK. Lipolytic actions of secretin in mouse adipocytes. J Lipid Res. 2014 Feb;55(2):190-200. PMID: 24273196.

Miegueu P, Cianflone K, Richard D, et al. Effect of secretin on preadipocyte, differentiating and mature adipocyte functions. Int J Obes (Lond). 2013 Mar;37(3):366-74. PMID: 22565418.

Heinzlmann A, Kiss G, Tóth ZE, et al. Intranasal application of secretin, similarly to intracerebroventricular administration, influences the motor behavior of mice probably through specific receptors. J Mol Neurosci. 2012 Nov;48(3):558-64. PMID: 22752505.

Mahata M, Zhang K, Gayen JR, et al. Catecholamine biosynthesis and secretion: physiological and pharmacological effects of secretin. Cell Tissue Res. 2011 Jul;345(1):87-102. PMID: 21597914.

" Not dangerous goods.

LKT M5776 Motilin, pig 0.5 mg 228 Endogenous peptide hormone, involved in enteric movement; motilin agonist. 52906-92-0 ≥98% 2699.1 C120H188N34O35S CCC(C)C(C(=O)NC(CC1=CC=CC=C1)C(=O)NC(C(C)O)C(=O)NC(CC2=CC=C(C=C2)O)C(=O)NCC(=O)NC(CCC(=O)O)C(=O)NC(CC(C)C)C(=O)NC(CCC(=O)N)C(=O)NC(CCCNC(=N)N)C(=O)NC(CCSC)C(=O)NC(CCC(=O)N)C(=O)NC(CCC(=O)O)C(=O)NC(CCCCN)C(=O)NC(CCC(=O)O)C(=O)NC(CCCNC(=N)N)C(=O)NC(CC(=O)N)C(=O)NC(CCCCN)C(=O)NCC(=O)NC(CCC(=O)N)C(=O)O)NC(=O)C3CCCN3C(=O)C(C(C)C)NC(=O)C(CC4=CC=CC=C4)N Ambient -20°C "Sanger GJ, Wang Y, Hobson A, et al. Motilin: towards a new understanding of the gastrointestinal neuropharmacology and therapeutic use of motilin receptor agonists. Br J Pharmacol. 2013 Dec;170(7):1323-32. PMID: 23189978.

Feng B, Liu JC, Zhang J, et al. Anxiolytic actions of motilin in the basolateral amygdala. Mol Neurobiol. 2013 Jun;47(3):892-902. PMID: 23307330.

Miegueu P, Cianflone K, Richard D, et al. Motilin stimulates preadipocyte proliferation and differentiation and adipocyte lipid storage. Am J Physiol Endocrinol Metab. 2011 Nov;301(5):E758-66. PMID: 21771971.

Piche T, Galmiche JP. Pharmacological targets in gastro-oesophageal reflux disease. Basic Clin Pharmacol Toxicol. 2005 Dec;97(6):333-41. PMID: 16364047.

" Not dangerous goods.

LKT M5776 Motilin, pig 1 mg 387 Endogenous peptide hormone, involved in enteric movement; motilin agonist. 52906-92-0 ≥98% 2699.1 C120H188N34O35S CCC(C)C(C(=O)NC(CC1=CC=CC=C1)C(=O)NC(C(C)O)C(=O)NC(CC2=CC=C(C=C2)O)C(=O)NCC(=O)NC(CCC(=O)O)C(=O)NC(CC(C)C)C(=O)NC(CCC(=O)N)C(=O)NC(CCCNC(=N)N)C(=O)NC(CCSC)C(=O)NC(CCC(=O)N)C(=O)NC(CCC(=O)O)C(=O)NC(CCCCN)C(=O)NC(CCC(=O)O)C(=O)NC(CCCNC(=N)N)C(=O)NC(CC(=O)N)C(=O)NC(CCCCN)C(=O)NCC(=O)NC(CCC(=O)N)C(=O)O)NC(=O)C3CCCN3C(=O)C(C(C)C)NC(=O)C(CC4=CC=CC=C4)N Ambient -20°C "Sanger GJ, Wang Y, Hobson A, et al. Motilin: towards a new understanding of the gastrointestinal neuropharmacology and therapeutic use of motilin receptor agonists. Br J Pharmacol. 2013 Dec;170(7):1323-32. PMID: 23189978.

Feng B, Liu JC, Zhang J, et al. Anxiolytic actions of motilin in the basolateral amygdala. Mol Neurobiol. 2013 Jun;47(3):892-902. PMID: 23307330.

Miegueu P, Cianflone K, Richard D, et al. Motilin stimulates preadipocyte proliferation and differentiation and adipocyte lipid storage. Am J Physiol Endocrinol Metab. 2011 Nov;301(5):E758-66. PMID: 21771971.

Piche T, Galmiche JP. Pharmacological targets in gastro-oesophageal reflux disease. Basic Clin Pharmacol Toxicol. 2005 Dec;97(6):333-41. PMID: 16364047.

" Not dangerous goods.

LKT M5776 Motilin, pig 2.5 mg 684.1 Endogenous peptide hormone, involved in enteric movement; motilin agonist. 52906-92-0 ≥98% 2699.1 C120H188N34O35S CCC(C)C(C(=O)NC(CC1=CC=CC=C1)C(=O)NC(C(C)O)C(=O)NC(CC2=CC=C(C=C2)O)C(=O)NCC(=O)NC(CCC(=O)O)C(=O)NC(CC(C)C)C(=O)NC(CCC(=O)N)C(=O)NC(CCCNC(=N)N)C(=O)NC(CCSC)C(=O)NC(CCC(=O)N)C(=O)NC(CCC(=O)O)C(=O)NC(CCCCN)C(=O)NC(CCC(=O)O)C(=O)NC(CCCNC(=N)N)C(=O)NC(CC(=O)N)C(=O)NC(CCCCN)C(=O)NCC(=O)NC(CCC(=O)N)C(=O)O)NC(=O)C3CCCN3C(=O)C(C(C)C)NC(=O)C(CC4=CC=CC=C4)N Ambient -20°C "Sanger GJ, Wang Y, Hobson A, et al. Motilin: towards a new understanding of the gastrointestinal neuropharmacology and therapeutic use of motilin receptor agonists. Br J Pharmacol. 2013 Dec;170(7):1323-32. PMID: 23189978.

Feng B, Liu JC, Zhang J, et al. Anxiolytic actions of motilin in the basolateral amygdala. Mol Neurobiol. 2013 Jun;47(3):892-902. PMID: 23307330.

Miegueu P, Cianflone K, Richard D, et al. Motilin stimulates preadipocyte proliferation and differentiation and adipocyte lipid storage. Am J Physiol Endocrinol Metab. 2011 Nov;301(5):E758-66. PMID: 21771971.

Piche T, Galmiche JP. Pharmacological targets in gastro-oesophageal reflux disease. Basic Clin Pharmacol Toxicol. 2005 Dec;97(6):333-41. PMID: 16364047.

" Not dangerous goods.

LKT M5794 Moxifloxacin Hydrochloride 100 mg 151.7 Fluoroquinolone; topoisomerase IV, topoisomerase II, and bacterial DNA gyrase inhibitor. "1-Cyclopropyl-6-fluoro-1,4-dihydro-8-methoxy-7- [(4aS,7aS)-octahydro-6H-pyrrolo[3,4-b]pyridin-6-yl]- 4-oxo-3-quinolinecarboxylic acid hydrochloride

" Actura; Avalox; Avelox; Octegra; Proflox 186826-86-8 ≥98% 437.89 C21H24FN3O4 HCl COC1=C2C(=CC(=C1N3CC4CCCNC4C3)F)C(=O)C(=CN2C5CC5)C(=O)O.Cl Ambient 4°C Soluble in water (2.4 g/100 ml). Methanol, DMSO "Wohlkonig A, Chan PF, Fosberry AP, et al. Structural basis of quinolone inhibition of type IIA topoisomerases and target-mediated resistance. Nat Struct Mol Biol. 2010 Sep;17(9):1152-3. PMID: 20802486.

Reuveni D, Halperin D, Shalit I, et al. Moxifloxacin enhances etoposide-induced cytotoxic, apoptotic and anti-topoisomerase II effects in a human colon carcinoma cell line. Int J Oncol. 2010 Aug;37(2):463-71. PMID: 20596674.

Reuveni D, Halperin D, Fabian I, et al. Moxifloxacin increases anti-tumor and anti-angiogenic activity of irinotecan in human xenograft tumors. Biochem Pharmacol. 2010 Apr 15;79(8):1100-7. PMID: 20025849.

Laponogov I, Sohi MK, Veselkov DA, et al. Structural insight into the quinolone-DNA cleavage complex of type IIA topoisomerases. Nat Struct Mol Biol. 2009 Jun;16(6):667-9. PMID: 19448616.

Stroman DW, Dajcs JJ, Cupp GA, et al. In vitro and in vivo potency of moxifloxacin and moxifloxacin ophthalmic solution 0.5%, a new topical fluoroquinolone. Surv Ophthalmol. 2005 Nov;50 Suppl 1:S16-31. PMID: 16257308.

Aldred KJ, McPherson SA, Wang P, et al. Drug interactions with Bacillus anthracis topoisomerase IV: biochemical basis for quinolone action and resistance. Biochemistry. 2012 Jan 10;51(1):370-381. PMID: 22126453.

" None Not dangerous goods.

LKT M5794 Moxifloxacin Hydrochloride 500 mg 582.4 Fluoroquinolone; topoisomerase IV, topoisomerase II, and bacterial DNA gyrase inhibitor. "1-Cyclopropyl-6-fluoro-1,4-dihydro-8-methoxy-7- [(4aS,7aS)-octahydro-6H-pyrrolo[3,4-b]pyridin-6-yl]- 4-oxo-3-quinolinecarboxylic acid hydrochloride

" Actura; Avalox; Avelox; Octegra; Proflox 186826-86-8 ≥98% 437.89 C21H24FN3O4 HCl COC1=C2C(=CC(=C1N3CC4CCCNC4C3)F)C(=O)C(=CN2C5CC5)C(=O)O.Cl Ambient 4°C Soluble in water (2.4 g/100 ml). Methanol, DMSO "Wohlkonig A, Chan PF, Fosberry AP, et al. Structural basis of quinolone inhibition of type IIA topoisomerases and target-mediated resistance. Nat Struct Mol Biol. 2010 Sep;17(9):1152-3. PMID: 20802486.

Reuveni D, Halperin D, Shalit I, et al. Moxifloxacin enhances etoposide-induced cytotoxic, apoptotic and anti-topoisomerase II effects in a human colon carcinoma cell line. Int J Oncol. 2010 Aug;37(2):463-71. PMID: 20596674.

Reuveni D, Halperin D, Fabian I, et al. Moxifloxacin increases anti-tumor and anti-angiogenic activity of irinotecan in human xenograft tumors. Biochem Pharmacol. 2010 Apr 15;79(8):1100-7. PMID: 20025849.

Laponogov I, Sohi MK, Veselkov DA, et al. Structural insight into the quinolone-DNA cleavage complex of type IIA topoisomerases. Nat Struct Mol Biol. 2009 Jun;16(6):667-9. PMID: 19448616.

Stroman DW, Dajcs JJ, Cupp GA, et al. In vitro and in vivo potency of moxifloxacin and moxifloxacin ophthalmic solution 0.5%, a new topical fluoroquinolone. Surv Ophthalmol. 2005 Nov;50 Suppl 1:S16-31. PMID: 16257308.

Aldred KJ, McPherson SA, Wang P, et al. Drug interactions with Bacillus anthracis topoisomerase IV: biochemical basis for quinolone action and resistance. Biochemistry. 2012 Jan 10;51(1):370-381. PMID: 22126453.

" None Not dangerous goods.

LKT M5794 Moxifloxacin Hydrochloride 1 g 952.5 Fluoroquinolone; topoisomerase IV, topoisomerase II, and bacterial DNA gyrase inhibitor. "1-Cyclopropyl-6-fluoro-1,4-dihydro-8-methoxy-7- [(4aS,7aS)-octahydro-6H-pyrrolo[3,4-b]pyridin-6-yl]- 4-oxo-3-quinolinecarboxylic acid hydrochloride

" Actura; Avalox; Avelox; Octegra; Proflox 186826-86-8 ≥98% 437.89 C21H24FN3O4 HCl COC1=C2C(=CC(=C1N3CC4CCCNC4C3)F)C(=O)C(=CN2C5CC5)C(=O)O.Cl Ambient 4°C Soluble in water (2.4 g/100 ml). Methanol, DMSO "Wohlkonig A, Chan PF, Fosberry AP, et al. Structural basis of quinolone inhibition of type IIA topoisomerases and target-mediated resistance. Nat Struct Mol Biol. 2010 Sep;17(9):1152-3. PMID: 20802486.

Reuveni D, Halperin D, Shalit I, et al. Moxifloxacin enhances etoposide-induced cytotoxic, apoptotic and anti-topoisomerase II effects in a human colon carcinoma cell line. Int J Oncol. 2010 Aug;37(2):463-71. PMID: 20596674.

Reuveni D, Halperin D, Fabian I, et al. Moxifloxacin increases anti-tumor and anti-angiogenic activity of irinotecan in human xenograft tumors. Biochem Pharmacol. 2010 Apr 15;79(8):1100-7. PMID: 20025849.

Laponogov I, Sohi MK, Veselkov DA, et al. Structural insight into the quinolone-DNA cleavage complex of type IIA topoisomerases. Nat Struct Mol Biol. 2009 Jun;16(6):667-9. PMID: 19448616.

Stroman DW, Dajcs JJ, Cupp GA, et al. In vitro and in vivo potency of moxifloxacin and moxifloxacin ophthalmic solution 0.5%, a new topical fluoroquinolone. Surv Ophthalmol. 2005 Nov;50 Suppl 1:S16-31. PMID: 16257308.

Aldred KJ, McPherson SA, Wang P, et al. Drug interactions with Bacillus anthracis topoisomerase IV: biochemical basis for quinolone action and resistance. Biochemistry. 2012 Jan 10;51(1):370-381. PMID: 22126453.

" None Not dangerous goods.

LKT S1605 Secretin, human 1 mg 228 Endogenous peptide hormone, involved in water homeostasis and feeding behavior; SCTR agonist. SecreFlo 108153-74-8 ≥95% 3039.4 C130H220N44O40 CC(C)CC(C(=O)NC(C(C)C)C(=O)O)NC(=O)CNC(=O)C(CCC(=O)N)NC(=O)C(CC(C)C)NC(=O)C(CC(C)C)NC(=O)C(CCCNC(=N)N)NC(=O)C(CCC(=O)N)NC(=O)C(CC(C)C)NC(=O)C(CCCNC(=N)N)NC(=O)C(C)NC(=O)C(CO)NC(=O)C(CC(=O)O)NC(=O)C(CCCNC(=N)N)NC(=O)C(CC(C)C)NC(=O)C(CCCNC(=N)N)NC(=O)C(CO)NC(=O)C(CC(C)C)NC(=O)C(CCC(=O)O)NC(=O)C(CO)NC(=O)C(C(C)O)NC(=O)C(CC1=CC=CC=C1)NC(=O)C(C(C)O)NC(=O)CNC(=O)C(CC(=O)O)NC(=O)C(CO)NC(=O)C(CC2=NC=CN2)N Ambient -20°C Soluble in water or saline. "Sekar R, Chow BK. Lipolytic actions of secretin in mouse adipocytes. J Lipid Res. 2014 Feb;55(2):190-200. PMID: 24273196.

Miegueu P, Cianflone K, Richard D, et al. Effect of secretin on preadipocyte, differentiating and mature adipocyte functions. Int J Obes (Lond). 2013 Mar;37(3):366-74. PMID: 22565418.

Heinzlmann A, Kiss G, Tóth ZE, et al. Intranasal application of secretin, similarly to intracerebroventricular administration, influences the motor behavior of mice probably through specific receptors. J Mol Neurosci. 2012 Nov;48(3):558-64. PMID: 22752505.

Mahata M, Zhang K, Gayen JR, et al. Catecholamine biosynthesis and secretion: physiological and pharmacological effects of secretin. Cell Tissue Res. 2011 Jul;345(1):87-102. PMID: 21597914.

" Not dangerous goods.

LKT S1605 Secretin, human 2 mg 356.9 Endogenous peptide hormone, involved in water homeostasis and feeding behavior; SCTR agonist. SecreFlo 108153-74-8 ≥95% 3039.4 C130H220N44O40 CC(C)CC(C(=O)NC(C(C)C)C(=O)O)NC(=O)CNC(=O)C(CCC(=O)N)NC(=O)C(CC(C)C)NC(=O)C(CC(C)C)NC(=O)C(CCCNC(=N)N)NC(=O)C(CCC(=O)N)NC(=O)C(CC(C)C)NC(=O)C(CCCNC(=N)N)NC(=O)C(C)NC(=O)C(CO)NC(=O)C(CC(=O)O)NC(=O)C(CCCNC(=N)N)NC(=O)C(CC(C)C)NC(=O)C(CCCNC(=N)N)NC(=O)C(CO)NC(=O)C(CC(C)C)NC(=O)C(CCC(=O)O)NC(=O)C(CO)NC(=O)C(C(C)O)NC(=O)C(CC1=CC=CC=C1)NC(=O)C(C(C)O)NC(=O)CNC(=O)C(CC(=O)O)NC(=O)C(CO)NC(=O)C(CC2=NC=CN2)N Ambient -20°C Soluble in water or saline. "Sekar R, Chow BK. Lipolytic actions of secretin in mouse adipocytes. J Lipid Res. 2014 Feb;55(2):190-200. PMID: 24273196.

Miegueu P, Cianflone K, Richard D, et al. Effect of secretin on preadipocyte, differentiating and mature adipocyte functions. Int J Obes (Lond). 2013 Mar;37(3):366-74. PMID: 22565418.

Heinzlmann A, Kiss G, Tóth ZE, et al. Intranasal application of secretin, similarly to intracerebroventricular administration, influences the motor behavior of mice probably through specific receptors. J Mol Neurosci. 2012 Nov;48(3):558-64. PMID: 22752505.

Mahata M, Zhang K, Gayen JR, et al. Catecholamine biosynthesis and secretion: physiological and pharmacological effects of secretin. Cell Tissue Res. 2011 Jul;345(1):87-102. PMID: 21597914.

" Not dangerous goods.

LKT S1605 Secretin, human 5 mg 684.1 Endogenous peptide hormone, involved in water homeostasis and feeding behavior; SCTR agonist. SecreFlo 108153-74-8 ≥95% 3039.4 C130H220N44O40 CC(C)CC(C(=O)NC(C(C)C)C(=O)O)NC(=O)CNC(=O)C(CCC(=O)N)NC(=O)C(CC(C)C)NC(=O)C(CC(C)C)NC(=O)C(CCCNC(=N)N)NC(=O)C(CCC(=O)N)NC(=O)C(CC(C)C)NC(=O)C(CCCNC(=N)N)NC(=O)C(C)NC(=O)C(CO)NC(=O)C(CC(=O)O)NC(=O)C(CCCNC(=N)N)NC(=O)C(CC(C)C)NC(=O)C(CCCNC(=N)N)NC(=O)C(CO)NC(=O)C(CC(C)C)NC(=O)C(CCC(=O)O)NC(=O)C(CO)NC(=O)C(C(C)O)NC(=O)C(CC1=CC=CC=C1)NC(=O)C(C(C)O)NC(=O)CNC(=O)C(CC(=O)O)NC(=O)C(CO)NC(=O)C(CC2=NC=CN2)N Ambient -20°C Soluble in water or saline. "Sekar R, Chow BK. Lipolytic actions of secretin in mouse adipocytes. J Lipid Res. 2014 Feb;55(2):190-200. PMID: 24273196.

Miegueu P, Cianflone K, Richard D, et al. Effect of secretin on preadipocyte, differentiating and mature adipocyte functions. Int J Obes (Lond). 2013 Mar;37(3):366-74. PMID: 22565418.

Heinzlmann A, Kiss G, Tóth ZE, et al. Intranasal application of secretin, similarly to intracerebroventricular administration, influences the motor behavior of mice probably through specific receptors. J Mol Neurosci. 2012 Nov;48(3):558-64. PMID: 22752505.

Mahata M, Zhang K, Gayen JR, et al. Catecholamine biosynthesis and secretion: physiological and pharmacological effects of secretin. Cell Tissue Res. 2011 Jul;345(1):87-102. PMID: 21597914.

" Not dangerous goods.

LKT S1343 Ac-SDKP 5 mg 144 Peptide, degradation product of thymosin B4, involved in hematopoiesis. Goralatide 120081-14-3 ≥95% 487.51 C20H33N5O9 CC(=O)NC(CO)C(=O)NC(CC(=O)O)C(=O)NC(CCCCN)C(=O)N1CCCC1C(=O)O Ambient -20°C "Song M, Jang H, Lee J, et al. Regeneration of chronic myocardial infarction by injectable hydrogels containing stem cell homing factor SDF-1 and angiogenic peptide Ac-SDKP. Biomaterials. 2014 Mar;35(8):2436-45. PMID: 24378015.

González GE, Rhaleb NE, Nakagawa P, et al. N-acetyl-seryl-aspartyl-lysyl-proline reduces cardiac collagen cross-linking and inflammation in angiotensin II-induced hypertensive rats. Clin Sci (Lond). 2014 Jan 1;126(1):85-94. PMID: 23834332.

Zuo Y, Chun B, Potthoff SA, et al. Thymosin β4 and its degradation product, Ac-SDKP, are novel reparative factors in renal fibrosis. Kidney Int. 2013 Dec;84(6):1166-75. PMID: 23739235.

Tan H, Zhao J, Wang S, et al. Ac-SDKP ameliorates the progression of lupus nephritis in MRL/lpr mice. Int Immunopharmacol. 2012 Dec;14(4):401-9. PMID: 22922317.

Lenfant M, Wdzieczak-Bakala J, Guittet E, et al. Inhibitor of hematopoietic pluripotent stem cell proliferation: purification and determination of its structure. Proc Natl Acad Sci U S A. 1989 Feb;86(3):779-82. PMID: 2915977.

" Not dangerous goods.

LKT S1343 Ac-SDKP 10 mg 245.9 Peptide, degradation product of thymosin B4, involved in hematopoiesis. Goralatide 120081-14-3 ≥95% 487.51 C20H33N5O9 CC(=O)NC(CO)C(=O)NC(CC(=O)O)C(=O)NC(CCCCN)C(=O)N1CCCC1C(=O)O Ambient -20°C "Song M, Jang H, Lee J, et al. Regeneration of chronic myocardial infarction by injectable hydrogels containing stem cell homing factor SDF-1 and angiogenic peptide Ac-SDKP. Biomaterials. 2014 Mar;35(8):2436-45. PMID: 24378015.

González GE, Rhaleb NE, Nakagawa P, et al. N-acetyl-seryl-aspartyl-lysyl-proline reduces cardiac collagen cross-linking and inflammation in angiotensin II-induced hypertensive rats. Clin Sci (Lond). 2014 Jan 1;126(1):85-94. PMID: 23834332.

Zuo Y, Chun B, Potthoff SA, et al. Thymosin β4 and its degradation product, Ac-SDKP, are novel reparative factors in renal fibrosis. Kidney Int. 2013 Dec;84(6):1166-75. PMID: 23739235.

Tan H, Zhao J, Wang S, et al. Ac-SDKP ameliorates the progression of lupus nephritis in MRL/lpr mice. Int Immunopharmacol. 2012 Dec;14(4):401-9. PMID: 22922317.

Lenfant M, Wdzieczak-Bakala J, Guittet E, et al. Inhibitor of hematopoietic pluripotent stem cell proliferation: purification and determination of its structure. Proc Natl Acad Sci U S A. 1989 Feb;86(3):779-82. PMID: 2915977.

" Not dangerous goods.

LKT S1343 Ac-SDKP 25 mg 432 Peptide, degradation product of thymosin B4, involved in hematopoiesis. Goralatide 120081-14-3 ≥95% 487.51 C20H33N5O9 CC(=O)NC(CO)C(=O)NC(CC(=O)O)C(=O)NC(CCCCN)C(=O)N1CCCC1C(=O)O Ambient -20°C "Song M, Jang H, Lee J, et al. Regeneration of chronic myocardial infarction by injectable hydrogels containing stem cell homing factor SDF-1 and angiogenic peptide Ac-SDKP. Biomaterials. 2014 Mar;35(8):2436-45. PMID: 24378015.

González GE, Rhaleb NE, Nakagawa P, et al. N-acetyl-seryl-aspartyl-lysyl-proline reduces cardiac collagen cross-linking and inflammation in angiotensin II-induced hypertensive rats. Clin Sci (Lond). 2014 Jan 1;126(1):85-94. PMID: 23834332.

Zuo Y, Chun B, Potthoff SA, et al. Thymosin β4 and its degradation product, Ac-SDKP, are novel reparative factors in renal fibrosis. Kidney Int. 2013 Dec;84(6):1166-75. PMID: 23739235.

Tan H, Zhao J, Wang S, et al. Ac-SDKP ameliorates the progression of lupus nephritis in MRL/lpr mice. Int Immunopharmacol. 2012 Dec;14(4):401-9. PMID: 22922317.

Lenfant M, Wdzieczak-Bakala J, Guittet E, et al. Inhibitor of hematopoietic pluripotent stem cell proliferation: purification and determination of its structure. Proc Natl Acad Sci U S A. 1989 Feb;86(3):779-82. PMID: 2915977.

" Not dangerous goods.

LKT S1069 Scriptaid 1 mg 101.7 HDAC inhibitor. 6-(1,3-Dioxo-1H,3H-benzo[de]isoquinolin-2-yl)- hexanoic acid hydroxyamide CGK1026 ≥98% 326.35 C18H18N2O4 C1=CC2=C3C(=C1)C(=O)N(C(=O)C3=CC=C2)CCCCCC(=O)NO Protect from light. Ambient 4°C Soluble in DMSO (1mg/mL) or methanol. "Bui HT, Seo HJ, Park MR, et al. Histone deacetylase inhibition improves activation of ribosomal RNA genes and embryonic nucleolar reprogramming in cloned mouse embryos. Biol Reprod. 2011 Nov;85(5):1048-56. PMID: 21753193.

Brazelle W, Kreahling JM, Gemmer J, et al. Histone deacetylase inhibitors downregulate checkpoint kinase 1 expression to induce cell death in non-small cell lung cancer cells. PLoS One. 2010 Dec 14;5(12):e14335. PMID: 21179472.

Sharma V, Koul N, Joseph C, et al. HDAC inhibitor, scriptaid, induces glioma cell apoptosis through JNK activation and inhibits telomerase activity. J Cell Mol Med. 2010 Aug;14(8):2151-61. PMID: 19583803.

" Not dangerous goods.

LKT S1069 Scriptaid 5 mg 390.7 HDAC inhibitor. 6-(1,3-Dioxo-1H,3H-benzo[de]isoquinolin-2-yl)- hexanoic acid hydroxyamide CGK1026 ≥98% 326.35 C18H18N2O4 C1=CC2=C3C(=C1)C(=O)N(C(=O)C3=CC=C2)CCCCCC(=O)NO Protect from light. Ambient 4°C Soluble in DMSO (1mg/mL) or methanol. "Bui HT, Seo HJ, Park MR, et al. Histone deacetylase inhibition improves activation of ribosomal RNA genes and embryonic nucleolar reprogramming in cloned mouse embryos. Biol Reprod. 2011 Nov;85(5):1048-56. PMID: 21753193.

Brazelle W, Kreahling JM, Gemmer J, et al. Histone deacetylase inhibitors downregulate checkpoint kinase 1 expression to induce cell death in non-small cell lung cancer cells. PLoS One. 2010 Dec 14;5(12):e14335. PMID: 21179472.

Sharma V, Koul N, Joseph C, et al. HDAC inhibitor, scriptaid, induces glioma cell apoptosis through JNK activation and inhibits telomerase activity. J Cell Mol Med. 2010 Aug;14(8):2151-61. PMID: 19583803.

" Not dangerous goods.

LKT S1061 Small Cardioactive Peptide B 1 mg 72.1 Peptide found in molluscs, cardiomodulator. SCPB 84746-43-0 ≥95% 1141.43 C52H80N14O11S2 CC(C)CC(C(=O)NC(C)C(=O)NC(CC1=CC=CC=C1)C(=O)N2CCCC2C(=O)NC(CCCN=C(N)N)C(=O)NC(CCSC)C(=O)N)NC(=O)C(CC3=CC=C(C=C3)O)NC(=O)C(CC(=O)N)NC(=O)C(CCSC)N Ambient -20°C "Fox LE, Lloyd PE. Role of cAMP in the short-term modulation of a neuromuscular system in aplysia. J Neurophysiol. 2000 Mar;83(3):1567-79. PMID: 10712480.

Storozhuk M, Castellucci VF. Modulation of cholinergic transmission in the neuronal network of the gill and siphon withdrawal reflex in Aplysia. Neuroscience. 1999 Apr;90(1):291-301. PMID: 10188955.

Perry SJ, Dobbins AC, Schofield MG, et al. Small cardioactive peptide gene: structure, expression and mass spectrometric analysis reveals a complex pattern of co-transmitters in a snail feeding neuron. Eur J Neurosci. 1999 Feb;11(2):655-62. PMID: 10051766.

Norekian TP, Satterlie RA. Small cardioactive peptide B increases the responsiveness of the neural system underlying prey capture reactions in the pteropod mollusc, Clione limacina. J Exp Zool. 1994 Oct 1;270(2):136-47. PMID: 7999153.

Whim MD, Lloyd PE. Neuropeptide cotransmitters released from an identified cholinergic motor neuron modulate neuromuscular efficacy in Aplysia. J Neurosci. 1990 Oct;10(10):3313-22. PMID: 1976768.

" Not dangerous goods.

LKT S1061 Small Cardioactive Peptide B 2 mg 123.1 Peptide found in molluscs, cardiomodulator. SCPB 84746-43-0 ≥95% 1141.43 C52H80N14O11S2 CC(C)CC(C(=O)NC(C)C(=O)NC(CC1=CC=CC=C1)C(=O)N2CCCC2C(=O)NC(CCCN=C(N)N)C(=O)NC(CCSC)C(=O)N)NC(=O)C(CC3=CC=C(C=C3)O)NC(=O)C(CC(=O)N)NC(=O)C(CCSC)N Ambient -20°C "Fox LE, Lloyd PE. Role of cAMP in the short-term modulation of a neuromuscular system in aplysia. J Neurophysiol. 2000 Mar;83(3):1567-79. PMID: 10712480.

Storozhuk M, Castellucci VF. Modulation of cholinergic transmission in the neuronal network of the gill and siphon withdrawal reflex in Aplysia. Neuroscience. 1999 Apr;90(1):291-301. PMID: 10188955.

Perry SJ, Dobbins AC, Schofield MG, et al. Small cardioactive peptide gene: structure, expression and mass spectrometric analysis reveals a complex pattern of co-transmitters in a snail feeding neuron. Eur J Neurosci. 1999 Feb;11(2):655-62. PMID: 10051766.

Norekian TP, Satterlie RA. Small cardioactive peptide B increases the responsiveness of the neural system underlying prey capture reactions in the pteropod mollusc, Clione limacina. J Exp Zool. 1994 Oct 1;270(2):136-47. PMID: 7999153.

Whim MD, Lloyd PE. Neuropeptide cotransmitters released from an identified cholinergic motor neuron modulate neuromuscular efficacy in Aplysia. J Neurosci. 1990 Oct;10(10):3313-22. PMID: 1976768.

" Not dangerous goods.

LKT S1061 Small Cardioactive Peptide B 5 mg 216.1 Peptide found in molluscs, cardiomodulator. SCPB 84746-43-0 ≥95% 1141.43 C52H80N14O11S2 CC(C)CC(C(=O)NC(C)C(=O)NC(CC1=CC=CC=C1)C(=O)N2CCCC2C(=O)NC(CCCN=C(N)N)C(=O)NC(CCSC)C(=O)N)NC(=O)C(CC3=CC=C(C=C3)O)NC(=O)C(CC(=O)N)NC(=O)C(CCSC)N Ambient -20°C "Fox LE, Lloyd PE. Role of cAMP in the short-term modulation of a neuromuscular system in aplysia. J Neurophysiol. 2000 Mar;83(3):1567-79. PMID: 10712480.

Storozhuk M, Castellucci VF. Modulation of cholinergic transmission in the neuronal network of the gill and siphon withdrawal reflex in Aplysia. Neuroscience. 1999 Apr;90(1):291-301. PMID: 10188955.

Perry SJ, Dobbins AC, Schofield MG, et al. Small cardioactive peptide gene: structure, expression and mass spectrometric analysis reveals a complex pattern of co-transmitters in a snail feeding neuron. Eur J Neurosci. 1999 Feb;11(2):655-62. PMID: 10051766.

Norekian TP, Satterlie RA. Small cardioactive peptide B increases the responsiveness of the neural system underlying prey capture reactions in the pteropod mollusc, Clione limacina. J Exp Zool. 1994 Oct 1;270(2):136-47. PMID: 7999153.

Whim MD, Lloyd PE. Neuropeptide cotransmitters released from an identified cholinergic motor neuron modulate neuromuscular efficacy in Aplysia. J Neurosci. 1990 Oct;10(10):3313-22. PMID: 1976768.

" Not dangerous goods.

LKT S1060 Small Cardioactive Peptide A 1 mg 72.1 Peptide found in molluscs, cardiomodulator. SCPA 98035-79-1 ≥95% 1277.57 C59H92N18O12S CC(C)CC(C(=O)NC(C)C(=O)NC(CC1=CC=CC=C1)C(=O)N2CCCC2C(=O)NC(CCCN=C(N)N)C(=O)NC(CCSC)C(=O)N)NC(=O)C(CC3=CC=C(C=C3)O)NC(=O)CNC(=O)C4CCCN4C(=O)C(CCCN=C(N)N)NC(=O)C(C)N Ambient -20°C "Fox LE, Lloyd PE. Role of cAMP in the short-term modulation of a neuromuscular system in aplysia. J Neurophysiol. 2000 Mar;83(3):1567-79. PMID: 10712480.

Storozhuk M, Castellucci VF. Modulation of cholinergic transmission in the neuronal network of the gill and siphon withdrawal reflex in Aplysia. Neuroscience. 1999 Apr;90(1):291-301. PMID: 10188955.

Perry SJ, Dobbins AC, Schofield MG, et al. Small cardioactive peptide gene: structure, expression and mass spectrometric analysis reveals a complex pattern of co-transmitters in a snail feeding neuron. Eur J Neurosci. 1999 Feb;11(2):655-62. PMID: 10051766.

Whim MD, Lloyd PE. Neuropeptide cotransmitters released from an identified cholinergic motor neuron modulate neuromuscular efficacy in Aplysia. J Neurosci. 1990 Oct;10(10):3313-22. PMID: 1976768.

" Not dangerous goods.

LKT S1060 Small Cardioactive Peptide A 2 mg 123.1 Peptide found in molluscs, cardiomodulator. SCPA 98035-79-1 ≥95% 1277.57 C59H92N18O12S CC(C)CC(C(=O)NC(C)C(=O)NC(CC1=CC=CC=C1)C(=O)N2CCCC2C(=O)NC(CCCN=C(N)N)C(=O)NC(CCSC)C(=O)N)NC(=O)C(CC3=CC=C(C=C3)O)NC(=O)CNC(=O)C4CCCN4C(=O)C(CCCN=C(N)N)NC(=O)C(C)N Ambient -20°C "Fox LE, Lloyd PE. Role of cAMP in the short-term modulation of a neuromuscular system in aplysia. J Neurophysiol. 2000 Mar;83(3):1567-79. PMID: 10712480.

Storozhuk M, Castellucci VF. Modulation of cholinergic transmission in the neuronal network of the gill and siphon withdrawal reflex in Aplysia. Neuroscience. 1999 Apr;90(1):291-301. PMID: 10188955.

Perry SJ, Dobbins AC, Schofield MG, et al. Small cardioactive peptide gene: structure, expression and mass spectrometric analysis reveals a complex pattern of co-transmitters in a snail feeding neuron. Eur J Neurosci. 1999 Feb;11(2):655-62. PMID: 10051766.

Whim MD, Lloyd PE. Neuropeptide cotransmitters released from an identified cholinergic motor neuron modulate neuromuscular efficacy in Aplysia. J Neurosci. 1990 Oct;10(10):3313-22. PMID: 1976768.

" Not dangerous goods.

LKT S1060 Small Cardioactive Peptide A 5 mg 216.1 Peptide found in molluscs, cardiomodulator. SCPA 98035-79-1 ≥95% 1277.57 C59H92N18O12S CC(C)CC(C(=O)NC(C)C(=O)NC(CC1=CC=CC=C1)C(=O)N2CCCC2C(=O)NC(CCCN=C(N)N)C(=O)NC(CCSC)C(=O)N)NC(=O)C(CC3=CC=C(C=C3)O)NC(=O)CNC(=O)C4CCCN4C(=O)C(CCCN=C(N)N)NC(=O)C(C)N Ambient -20°C "Fox LE, Lloyd PE. Role of cAMP in the short-term modulation of a neuromuscular system in aplysia. J Neurophysiol. 2000 Mar;83(3):1567-79. PMID: 10712480.

Storozhuk M, Castellucci VF. Modulation of cholinergic transmission in the neuronal network of the gill and siphon withdrawal reflex in Aplysia. Neuroscience. 1999 Apr;90(1):291-301. PMID: 10188955.

Perry SJ, Dobbins AC, Schofield MG, et al. Small cardioactive peptide gene: structure, expression and mass spectrometric analysis reveals a complex pattern of co-transmitters in a snail feeding neuron. Eur J Neurosci. 1999 Feb;11(2):655-62. PMID: 10051766.

Whim MD, Lloyd PE. Neuropeptide cotransmitters released from an identified cholinergic motor neuron modulate neuromuscular efficacy in Aplysia. J Neurosci. 1990 Oct;10(10):3313-22. PMID: 1976768.

" Not dangerous goods.

LKT S1058 Scopolamine N-butylbromide 1 g 47.6 Tropane alkaloid found in Solanaceae plants; M1 mAChR antagonist. Amisepan; Buscolamin; N-Butylhyoscine bromide; Tirantil  149-64-4 ≥98% 440.38 C21H30BrNO4 CCCC[N+]1(C2CC(CC1C3C2O3)OC(=O)C(CO)C4=CC=CC=C4)C.[Br-] Ambient Ambient Soluble in water and methylene chloride "Jung IH, Lee HE, Park SJ, et al. Ameliorating effect of spinosin, a C-glycoside flavonoid, on scopolamine-induced memory impairment in mice. Pharmacol Biochem Behav. 2014 May;120:88-94. PMID: 24582850.

Drevets WC, Zarate CA Jr, Furey ML. Antidepressant effects of the muscarinic cholinergic receptor antagonist scopolamine: a review. Biol Psychiatry. 2013 Jun 15;73(12):1156-63. PMID: 23200525.

" Xn Not dangerous goods.

LKT S1058 Scopolamine N-butylbromide 5 g 136 Tropane alkaloid found in Solanaceae plants; M1 mAChR antagonist. Amisepan; Buscolamin; N-Butylhyoscine bromide; Tirantil  149-64-4 ≥98% 440.38 C21H30BrNO4 CCCC[N+]1(C2CC(CC1C3C2O3)OC(=O)C(CO)C4=CC=CC=C4)C.[Br-] Ambient Ambient Soluble in water and methylene chloride "Jung IH, Lee HE, Park SJ, et al. Ameliorating effect of spinosin, a C-glycoside flavonoid, on scopolamine-induced memory impairment in mice. Pharmacol Biochem Behav. 2014 May;120:88-94. PMID: 24582850.

Drevets WC, Zarate CA Jr, Furey ML. Antidepressant effects of the muscarinic cholinergic receptor antagonist scopolamine: a review. Biol Psychiatry. 2013 Jun 15;73(12):1156-63. PMID: 23200525.

" Xn Not dangerous goods.

LKT S0930 Schisantherin A 5 mg 134.1 Dibenzocyclooctadiene found in Schisandra. Schizantherin A; Gomisin C; Wuweizi ester A 58546-56-8 ≥98% 536.58 C30H32O9 CC1CC2=CC3=C(C(=C2C4=C(C(=C(C=C4C(C1(C)O)OC(=O)C5=CC=CC=C5)OC)OC)OC)OC)OCO3 Ambient 4°C [α]D: -190.9° (c=0.995, CHCl3) "He Y, Zhang Q, Shen Y, et al. Schisantherin A suppresses osteoclast formation and wear particle-induced osteolysis via modulating RANKL signaling pathways. Biochem Biophys Res Commun. 2014 Jul 4;449(3):344-50. PMID: 24845381.

Li X, Zhao X, Xu X, et al. Schisantherin A recovers Aβ-induced neurodegeneration with cognitive decline in mice. Physiol Behav. 2014 Jun 10;132:10-6. PMID: 24813830.

Chang R, Li Y, Yang X, et al. Protective role of deoxyschizandrin and schisantherin A against myocardial ischemia-reperfusion injury in rats. PLoS One. 2013 Apr 19;8(4):e61590. PMID: 23620773.

Ci X, Ren R, Xu K, et al. Schisantherin A exhibits anti-inflammatory properties by down-regulating NF-kappaB and MAPK signaling pathways in lipopolysaccharide-treated RAW 264.7 cells. Inflammation. 2010 Apr;33(2):126-36. PMID: 20238486.

" Not dangerous goods.

LKT S0930 Schisantherin A 10 mg 219.7 Dibenzocyclooctadiene found in Schisandra. Schizantherin A; Gomisin C; Wuweizi ester A 58546-56-8 ≥98% 536.58 C30H32O9 CC1CC2=CC3=C(C(=C2C4=C(C(=C(C=C4C(C1(C)O)OC(=O)C5=CC=CC=C5)OC)OC)OC)OC)OCO3 Ambient 4°C [α]D: -190.9° (c=0.995, CHCl3) "He Y, Zhang Q, Shen Y, et al. Schisantherin A suppresses osteoclast formation and wear particle-induced osteolysis via modulating RANKL signaling pathways. Biochem Biophys Res Commun. 2014 Jul 4;449(3):344-50. PMID: 24845381.

Li X, Zhao X, Xu X, et al. Schisantherin A recovers Aβ-induced neurodegeneration with cognitive decline in mice. Physiol Behav. 2014 Jun 10;132:10-6. PMID: 24813830.

Chang R, Li Y, Yang X, et al. Protective role of deoxyschizandrin and schisantherin A against myocardial ischemia-reperfusion injury in rats. PLoS One. 2013 Apr 19;8(4):e61590. PMID: 23620773.

Ci X, Ren R, Xu K, et al. Schisantherin A exhibits anti-inflammatory properties by down-regulating NF-kappaB and MAPK signaling pathways in lipopolysaccharide-treated RAW 264.7 cells. Inflammation. 2010 Apr;33(2):126-36. PMID: 20238486.

" Not dangerous goods.

LKT M5853 Moniliformin 1 mg 364 Mycotoxin produced by species of Fusarium; potential pyruvate dehydrogenase inhibitor. 3-hydroxycyclobut-3-ene-1,2-dione 31876-38-7 ≥98% 98.06 C4H2O3 C1=C(C(=O)C1=O)O Ambient 4°C water, methanol "Scarpino V, Blandino M, Negre M, et al. Moniliformin analysis in maize samples from North-West Italy using multifunctional clean-up columns and the LC-MS/MS detection method. Food Addit Contam Part A Chem Anal Control Expo Risk Assess. 2013;30(5):876-84. PMID: 23731218.

Ficheux AS, Sibiril Y, Parent-Massin D. Effects of beauvericin, enniatin b and moniliformin on human dendritic cells and macrophages: an in vitro study. Toxicon. 2013 Sep;71:1-10. PMID: 23685117.

von Bargen KW, Lohrey L, Cramer B, et al. Analysis of the Fusarium mycotoxin moniliformin in cereal samples using 13C2-moniliformin and high-resolution mass spectrometry. J Agric Food Chem. 2012 Apr 11;60(14):3586-91. PMID: 22428531.

Zhang A, Cao JL, Yang B, et al. Effects of moniliformin and selenium on human articular cartilage metabolism and their potential relationships to the pathogenesis of Kashin-Beck disease. J Zhejiang Univ Sci B. 2010 Mar;11(3):200-8. PMID: 20205306.

Chen LY, Tian XL, Yang B. A study on the inhibition of rat myocardium glutathione peroxidase and glutathione reductase by moniliformin. Mycopathologia. 1990 May;110(2):119-24. PMID: 2366852.

Gathercole PS, Thiel PG, Hofmeyr JH. Inhibition of pyruvate dehydrogenase complex by moniliformin. Biochem J. 1986 Feb 1;233(3):719-23. PMID: 3707519.

" "UN number: 3462     Class: 6.1     Packing Group: II

Proper shipping name: Toxins, extracted from living sources, solid, n.o.s. (Moniliformin)"

LKT M7528 α-Melanocyte Stimulating Hormone 1 mg 201.8 Endogenous peptide hormone derived from POMC, involved in energy homeostasis and melanin production; MCR agonist. alpha-MSH; alpha-Melanotropin; α-MSH 581-05-5 ≥98% 1664.9 C77H109N21O19S CC(C)C(C(=O)N)NC(=O)C1CCCN1C(=O)C(CCCCN)NC(=O)CNC(=O)C(CC2=CNC3=CC=CC=C32)NC(=O)C(CCCNC(=N)N)NC(=O)C(CC4=CC=CC=C4)NC(=O)C(CC5=CNC=N5)NC(=O)C(CCC(=O)O)NC(=O)C(CCSC)NC(=O)C(CO)NC(=O)C(CC6=CC=C(C=C6)O)NC(=O)C(CO)NC(=O)C Ambient -20°C Soluble in water (1mg/mL). "Ma K, McLaurin J. α-Melanocyte Stimulating Hormone Prevents GABAergic Neuronal Loss and Improves Cognitive Function in Alzheimer's Disease. J Neurosci. 2014 May 14;34(20):6736-45. PMID: 24828629.

Zhang L, Dong L, Liu X, et al. α-Melanocyte-stimulating hormone protects retinal vascular endothelial cells from oxidative stress and apoptosis in a rat model of diabetes. PLoS One. 2014 Apr 2;9(4):e93433. PMID: 24695675.

Blagaić V, Houra K, Turcić P, et al. The influence of alpha-, beta-, and gamma-melanocyte stimulating hormone on acetaminophen induced liver lesions in male CBA mice. Molecules. 2010 Mar 3;15(3):1232-41. PMID: 20335976.

" Not dangerous goods.

LKT M7529 β-Melanocyte Stimulating Hormone, human 1 mg 369.8 Endogenous peptide hormone derived from POMC, involved in energy homeostasis and melanin production; MCR4 agonist. β-MSH 17908-57-5 ≥98% 2660.9 C118H174N34O35S Ambient -20°C "Blagaić V, Houra K, Turcić P, et al. The influence of alpha-, beta-, and gamma-melanocyte stimulating hormone on acetaminophen induced liver lesions in male CBA mice. Molecules. 2010 Mar 3;15(3):1232-41. PMID: 20335976.

Kamisoyama H, Honda K, Saneyasu T, et al. Corticotropin-releasing factor is a downstream mediator of the beta-melanocyte-stimulating hormone-induced anorexigenic pathway in chicks. Neurosci Lett. 2009 Jul 24;458(3):102-5. PMID: 19393716.

" Not dangerous goods.

LKT M7530 [Nle4, D-Phe7]-α-Melanocyte Stimulating Hormone 5 mg 168 Semi-synthetic peptide, melanocortin analog; MCR agonist. NDP-MSH, Melanotan I; afamelanotide ≥98% 1646.9 C78H111N21O19 Ambient -20°C "Lonati C, Carlin A, Leonardi P, et al. Modulatory effects of NDP-MSH in the regenerating liver after partial hepatectomy in rats. Peptides. 2013 Dec;50:145-52. PMID: 24446557.

Figueiredo J, Ferreira AE, Silva RL, et al. NDP-MSH inhibits neutrophil migration through nicotinic and adrenergic receptors in experimental peritonitis. Naunyn Schmiedebergs Arch Pharmacol. 2013 Apr;386(4):311-8. PMID: 23338711.

Gatti S, Lonati C, Acerbi F, et al. Protective action of NDP-MSH in experimental subarachnoid hemorrhage. Exp Neurol. 2012 Mar;234(1):230-8. PMID: 22230666.

" Not dangerous goods.

LKT M7531 γ-1 Melanocyte Stimulating Hormone 1 mg 201.8 Endogenous peptide hormone derived from POMC, involved in energy homeostasis and melanin production; MCR3 agonist. γ 1-MSH, gamma-1 MSH ≥98% 1512.8 C72H97N21O14S Ambient -20°C Jansone B, Bergstrom L, Svirskis S, et al. Opposite effects of gamma(1)- and gamma(2)-melanocyte stimulating hormone on regulation of the dopaminergic mesolimbic system in rats. Neurosci Lett. 2004 May 6;361(1-3):68-71. PMID: 15135895. Not dangerous goods.

LKT M7532 γ-3 Melanocyte Stimulating Hormone 1 mg 453.8 Endogenous peptide hormone derived from POMC, involved in energy homeostasis and melanin production; MCR3 agonist. γ 3-MSH ≥98% 2943.2 C126H188N44O37S Ambient -20°C "Slominski A, Costantino R, Wortsman J, et al. Melanotropic activity of gamma MSH peptides in melanoma cells. Life Sci. 1992;50(15):1103-8. PMID: 1556905.

Sharp B, Sowers JR. Adrenocortical response to corticotropin is inhibited by gamma 3-MSH antisera in normotensive and spontaneously hypertensive rats. Biochem Biophys Res Commun. 1983 Jan 27;110(2):357-63. PMID: 6301449.

"

LKT M9356 Myomodulin 1 mg 60 Myomodulin A , Myomoduline A 110570-93-9 ≥95% 846.13 C36H67N11O8S2 CC(C)CC(C(=O)N)NC(=O)C(CCCN=C(N)N)NC(=O)C(CC(C)C)NC(=O)C(CCSC)NC(=O)C(CO)NC(=O)C(CCSC)NC(=O)C1CCCN1 Ambient -20°C "Tobin AE, Calabrese RL. Myomodulin increases Ih and inhibits the NA/K pump to modulate bursting in leech heart interneurons. J Neurophysiol. 2005 Dec;94(6):3938-50. PMID: 16093342.

Britz FC, Deitmer JW. Membrane responses of the leech giant glial cell to the peptide transmitter myomodulin. Peptides. 2002 Dec;23(12):2117-25. PMID: 12535690.

Wang Y, Strong JA, Sahley CL. Modulatory effects of myomodulin on the excitability and membrane currents in Retzius cells of the leech. J Neurophysiol. 1999 Jul;82(1):216-25. PMID: 10400950.

Perry SJ, Straub VA, Kemenes G, et al. Neural modulation of gut motility by myomodulin peptides and acetylcholine in the snail Lymnaea. J Neurophysiol. 1998 May;79(5):2460-74. PMID: 9582220.

"

LKT M9356 Myomodulin 2 mg 101.9 Myomodulin A , Myomoduline A 110570-93-9 ≥95% 846.13 C36H67N11O8S2 CC(C)CC(C(=O)N)NC(=O)C(CCCN=C(N)N)NC(=O)C(CC(C)C)NC(=O)C(CCSC)NC(=O)C(CO)NC(=O)C(CCSC)NC(=O)C1CCCN1 Ambient -20°C "Tobin AE, Calabrese RL. Myomodulin increases Ih and inhibits the NA/K pump to modulate bursting in leech heart interneurons. J Neurophysiol. 2005 Dec;94(6):3938-50. PMID: 16093342.

Britz FC, Deitmer JW. Membrane responses of the leech giant glial cell to the peptide transmitter myomodulin. Peptides. 2002 Dec;23(12):2117-25. PMID: 12535690.

Wang Y, Strong JA, Sahley CL. Modulatory effects of myomodulin on the excitability and membrane currents in Retzius cells of the leech. J Neurophysiol. 1999 Jul;82(1):216-25. PMID: 10400950.

Perry SJ, Straub VA, Kemenes G, et al. Neural modulation of gut motility by myomodulin peptides and acetylcholine in the snail Lymnaea. J Neurophysiol. 1998 May;79(5):2460-74. PMID: 9582220.

"

LKT M9356 Myomodulin 5 mg 180 Myomodulin A , Myomoduline A 110570-93-9 ≥95% 846.13 C36H67N11O8S2 CC(C)CC(C(=O)N)NC(=O)C(CCCN=C(N)N)NC(=O)C(CC(C)C)NC(=O)C(CCSC)NC(=O)C(CO)NC(=O)C(CCSC)NC(=O)C1CCCN1 Ambient -20°C "Tobin AE, Calabrese RL. Myomodulin increases Ih and inhibits the NA/K pump to modulate bursting in leech heart interneurons. J Neurophysiol. 2005 Dec;94(6):3938-50. PMID: 16093342.

Britz FC, Deitmer JW. Membrane responses of the leech giant glial cell to the peptide transmitter myomodulin. Peptides. 2002 Dec;23(12):2117-25. PMID: 12535690.

Wang Y, Strong JA, Sahley CL. Modulatory effects of myomodulin on the excitability and membrane currents in Retzius cells of the leech. J Neurophysiol. 1999 Jul;82(1):216-25. PMID: 10400950.

Perry SJ, Straub VA, Kemenes G, et al. Neural modulation of gut motility by myomodulin peptides and acetylcholine in the snail Lymnaea. J Neurophysiol. 1998 May;79(5):2460-74. PMID: 9582220.

"

LKT M9367 Myricetin 10 mg 49.9 Flavonol found in fruits and vegetables; COMT inhibitor. 3,5,7-Trihydroxy-2-(3,4,5-trihydroxyphenyl)-4H-1- benzopyran-4-one Cannabiscetin; Delphidenolon 1575; Myricetol; Myricitin 529-44-2 ≥98% 318.23 C15H10O8 C1=C(C=C(C(=C1O)O)O)C2=C(C(=O)C3=C(C=C(C=C3O2)O)O)O Ambient 4°C Insoluble in water. Soluble in ethanol. "Maggioni D, Nicolini G, Rigolio R, et al. Myricetin and Naringenin Inhibit Human Squamous Cell Carcinoma Proliferation and Migration In Vitro. Nutr Cancer. 2014 Sep 25:1-11. PMID: 25256786.

Kandasamy N, Ashokkumar N. Renoprotective effect of myricetin restrains dyslipidemia and renal mesangial cell proliferation by the suppression of sterol regulatory element binding proteins in an experimental model of diabetic nephropathy. Eur J Pharmacol. 2014 Sep 18. [Epub ahead of print]. PMID: 25240712.

Kandasamy N, Ashokkumar N. Protective effect of bioflavonoid myricetin enhances carbohydrate metabolic enzymes and insulin signaling molecules in streptozotocin-cadmium induced diabetic nephrotoxic rats. Toxicol Appl Pharmacol. 2014 Sep 1;279(2):173-85. PMID: 24923654.

Ying X, Chen X, Feng Y, et al. Myricetin enhances osteogenic differentiation through the activation of canonical Wnt/β-catenin signaling in human bone marrow stromal cells. Eur J Pharmacol. 2014 Sep 5;738:22-30. PMID: 24876056.

Choi SM, Kim BC, Cho YH, et al. Effects of Flavonoid Compounds on β-amyloid-peptide-induced Neuronal Death in Cultured Mouse Cortical Neurons. Chonnam Med J. 2014 Aug;50(2):45-51. PMID: 25229015.

Lindqvist C, Bobrowska-Hägerstrand M, Mrówczyńska L, et al. Potentiation of natural killer cell activity with myricetin. Anticancer Res. 2014 Aug;34(8):3975-9. PMID: 25075019.

Sun H, Niisato N, Nishio K, et al. Distinct action of flavonoids, myricetin and quercetin, on epithelial Cl⁻ secretion: useful tools as regulators of Cl⁻ secretion. Biomed Res Int. 2014;2014:902735. PMID: 24818160.

Zhu X, Jia YH. Inhibition of catechol-o-methyltransferase (COMT) by myricetin, dihydromyricetin, and myricitrin. Pharmazie. 2014 Mar;69(3):183-6. PMID: 24716406.

" Not dangerous goods.

LKT M9367 Myricetin 25 mg 83.2 Flavonol found in fruits and vegetables; COMT inhibitor. 3,5,7-Trihydroxy-2-(3,4,5-trihydroxyphenyl)-4H-1- benzopyran-4-one Cannabiscetin; Delphidenolon 1575; Myricetol; Myricitin 529-44-2 ≥98% 318.23 C15H10O8 C1=C(C=C(C(=C1O)O)O)C2=C(C(=O)C3=C(C=C(C=C3O2)O)O)O Ambient 4°C Insoluble in water. Soluble in ethanol. "Maggioni D, Nicolini G, Rigolio R, et al. Myricetin and Naringenin Inhibit Human Squamous Cell Carcinoma Proliferation and Migration In Vitro. Nutr Cancer. 2014 Sep 25:1-11. PMID: 25256786.

Kandasamy N, Ashokkumar N. Renoprotective effect of myricetin restrains dyslipidemia and renal mesangial cell proliferation by the suppression of sterol regulatory element binding proteins in an experimental model of diabetic nephropathy. Eur J Pharmacol. 2014 Sep 18. [Epub ahead of print]. PMID: 25240712.

Kandasamy N, Ashokkumar N. Protective effect of bioflavonoid myricetin enhances carbohydrate metabolic enzymes and insulin signaling molecules in streptozotocin-cadmium induced diabetic nephrotoxic rats. Toxicol Appl Pharmacol. 2014 Sep 1;279(2):173-85. PMID: 24923654.

Ying X, Chen X, Feng Y, et al. Myricetin enhances osteogenic differentiation through the activation of canonical Wnt/β-catenin signaling in human bone marrow stromal cells. Eur J Pharmacol. 2014 Sep 5;738:22-30. PMID: 24876056.

Choi SM, Kim BC, Cho YH, et al. Effects of Flavonoid Compounds on β-amyloid-peptide-induced Neuronal Death in Cultured Mouse Cortical Neurons. Chonnam Med J. 2014 Aug;50(2):45-51. PMID: 25229015.

Lindqvist C, Bobrowska-Hägerstrand M, Mrówczyńska L, et al. Potentiation of natural killer cell activity with myricetin. Anticancer Res. 2014 Aug;34(8):3975-9. PMID: 25075019.

Sun H, Niisato N, Nishio K, et al. Distinct action of flavonoids, myricetin and quercetin, on epithelial Cl⁻ secretion: useful tools as regulators of Cl⁻ secretion. Biomed Res Int. 2014;2014:902735. PMID: 24818160.

Zhu X, Jia YH. Inhibition of catechol-o-methyltransferase (COMT) by myricetin, dihydromyricetin, and myricitrin. Pharmazie. 2014 Mar;69(3):183-6. PMID: 24716406.

" Not dangerous goods.

LKT M9608 Myclobutanil 5 g 51.1 14-α demethylase inhibitor. α-Butyl-α-(4-chlorophenyl)-1H-1,2,4-triazole-1- propanenitrile Nova; Rally; Systhane 88671-89-0 ≥97% 288.78 C15H17ClN4 CCCCC(CN1C=NC=N1)(C#N)C2=CC=C(C=C2)Cl Ambient Ambient Soluble in water and aromatic hydrocarbons. Insoluble in aliphatic hydrocarbons. "Goetz AK, Rockett JC, Ren H, et al. Inhibition of rat and human steroidogenesis by triazole antifungals. Syst Biol Reprod Med. 2009 Dec;55(5-6):214-26. PMID: 19938956.

Schnabel G, Jones AL. The 14alpha-Demethylasse(CYP51A1) Gene is Overexpressed in Venturia inaequalis Strains Resistant to Myclobutanil. Phytopathology. 2001 Jan;91(1):102-10. PMID: 18944284.

" N, Xn "UN number: 3077     Class: 9     Packing Group: III

Proper shipping name: Environmentally hazardous substance, solid, n.o.s. (Myclobutanil)"

LKT M9608 Myclobutanil 10 g 89.3 14-α demethylase inhibitor. α-Butyl-α-(4-chlorophenyl)-1H-1,2,4-triazole-1- propanenitrile Nova; Rally; Systhane 88671-89-0 ≥97% 288.78 C15H17ClN4 CCCCC(CN1C=NC=N1)(C#N)C2=CC=C(C=C2)Cl Ambient Ambient Soluble in water and aromatic hydrocarbons. Insoluble in aliphatic hydrocarbons. "Goetz AK, Rockett JC, Ren H, et al. Inhibition of rat and human steroidogenesis by triazole antifungals. Syst Biol Reprod Med. 2009 Dec;55(5-6):214-26. PMID: 19938956.

Schnabel G, Jones AL. The 14alpha-Demethylasse(CYP51A1) Gene is Overexpressed in Venturia inaequalis Strains Resistant to Myclobutanil. Phytopathology. 2001 Jan;91(1):102-10. PMID: 18944284.

" N, Xn "UN number: 3077     Class: 9     Packing Group: III

Proper shipping name: Environmentally hazardous substance, solid, n.o.s. (Myclobutanil)"

LKT M9608 Myclobutanil 50 g 317.9 14-α demethylase inhibitor. α-Butyl-α-(4-chlorophenyl)-1H-1,2,4-triazole-1- propanenitrile Nova; Rally; Systhane 88671-89-0 ≥97% 288.78 C15H17ClN4 CCCCC(CN1C=NC=N1)(C#N)C2=CC=C(C=C2)Cl Ambient Ambient Soluble in water and aromatic hydrocarbons. Insoluble in aliphatic hydrocarbons. "Goetz AK, Rockett JC, Ren H, et al. Inhibition of rat and human steroidogenesis by triazole antifungals. Syst Biol Reprod Med. 2009 Dec;55(5-6):214-26. PMID: 19938956.

Schnabel G, Jones AL. The 14alpha-Demethylasse(CYP51A1) Gene is Overexpressed in Venturia inaequalis Strains Resistant to Myclobutanil. Phytopathology. 2001 Jan;91(1):102-10. PMID: 18944284.

" N, Xn "UN number: 3077     Class: 9     Packing Group: III

Proper shipping name: Environmentally hazardous substance, solid, n.o.s. (Myclobutanil)"

LKT M9634 Myriocin 1 mg 33.8 Atypical amino acid found in Isaria sinclairi, parent compound of fingolimod; serine palmitoyltransferase inhibitor. 35891-70-4 ≥99%, TLC 401.54 C21H39NO6 CCCCCCC(=O)CCCCCCC=CCC(C(C(CO)(C(=O)O)N)O)O Ambient 4°C DMSO (25 mg/ml; heat briefly in boiling water bath); soluble in dilute base (50 mM NaOH) to ~5 mg/ml and methanol: 2 mg/mL "Wadsworth JM, Clarke DJ, McMahon SA, et al. The chemical basis of serine palmitoyltransferase inhibition by myriocin. J Am Chem Soc. 2013 Sep 25;135(38):14276-85. PMID: 23957439.

Lee YS, Choi KM, Choi MH, et al. Serine palmitoyltransferase inhibitor myriocin induces growth inhibition of B16F10 melanoma cells through G(2) /M phase arrest. Cell Prolif. 2011 Aug;44(4):320-9. PMID: 21645154.

Chiba K, Matsuyuki H, Maeda Y, et al. Role of sphingosine 1-phosphate receptor type 1 in lymphocyte egress from secondary lymphoid tissues and thymus. Cell Mol Immunol. 2006 Feb;3(1):11-9. PMID: 16549044.

Johnson VJ, He Q, Osuchowski MF, et al. Disruption of sphingolipid homeostasis by myriocin, a mycotoxin, reduces thymic and splenic T-lymphocyte populations. Toxicology. 2004 Sep 1;201(1-3):67-75. PMID: 15297021.

" Xn "UN number: 2811     Class:  6.1     Packing group:  III

Proper shipping name:  Toxic solids, organic, n.o.s. (Myriocin from Mycelia sterilia)

Marine pollutant:  No     Poison inhalation hazard:  No"

LKT M9634 Myriocin 5 mg 112.5 Atypical amino acid found in Isaria sinclairi, parent compound of fingolimod; serine palmitoyltransferase inhibitor. 35891-70-4 ≥99%, TLC 401.54 C21H39NO6 CCCCCCC(=O)CCCCCCC=CCC(C(C(CO)(C(=O)O)N)O)O Ambient 4°C DMSO (25 mg/ml; heat briefly in boiling water bath); soluble in dilute base (50 mM NaOH) to ~5 mg/ml and methanol: 2 mg/mL "Wadsworth JM, Clarke DJ, McMahon SA, et al. The chemical basis of serine palmitoyltransferase inhibition by myriocin. J Am Chem Soc. 2013 Sep 25;135(38):14276-85. PMID: 23957439.

Lee YS, Choi KM, Choi MH, et al. Serine palmitoyltransferase inhibitor myriocin induces growth inhibition of B16F10 melanoma cells through G(2) /M phase arrest. Cell Prolif. 2011 Aug;44(4):320-9. PMID: 21645154.

Chiba K, Matsuyuki H, Maeda Y, et al. Role of sphingosine 1-phosphate receptor type 1 in lymphocyte egress from secondary lymphoid tissues and thymus. Cell Mol Immunol. 2006 Feb;3(1):11-9. PMID: 16549044.

Johnson VJ, He Q, Osuchowski MF, et al. Disruption of sphingolipid homeostasis by myriocin, a mycotoxin, reduces thymic and splenic T-lymphocyte populations. Toxicology. 2004 Sep 1;201(1-3):67-75. PMID: 15297021.

" Xn "UN number: 2811     Class:  6.1     Packing group:  III

Proper shipping name:  Toxic solids, organic, n.o.s. (Myriocin from Mycelia sterilia)

Marine pollutant:  No     Poison inhalation hazard:  No"

LKT M9634 Myriocin 10 mg 187.4 Atypical amino acid found in Isaria sinclairi, parent compound of fingolimod; serine palmitoyltransferase inhibitor. 35891-70-4 ≥99%, TLC 401.54 C21H39NO6 CCCCCCC(=O)CCCCCCC=CCC(C(C(CO)(C(=O)O)N)O)O Ambient 4°C DMSO (25 mg/ml; heat briefly in boiling water bath); soluble in dilute base (50 mM NaOH) to ~5 mg/ml and methanol: 2 mg/mL "Wadsworth JM, Clarke DJ, McMahon SA, et al. The chemical basis of serine palmitoyltransferase inhibition by myriocin. J Am Chem Soc. 2013 Sep 25;135(38):14276-85. PMID: 23957439.

Lee YS, Choi KM, Choi MH, et al. Serine palmitoyltransferase inhibitor myriocin induces growth inhibition of B16F10 melanoma cells through G(2) /M phase arrest. Cell Prolif. 2011 Aug;44(4):320-9. PMID: 21645154.

Chiba K, Matsuyuki H, Maeda Y, et al. Role of sphingosine 1-phosphate receptor type 1 in lymphocyte egress from secondary lymphoid tissues and thymus. Cell Mol Immunol. 2006 Feb;3(1):11-9. PMID: 16549044.

Johnson VJ, He Q, Osuchowski MF, et al. Disruption of sphingolipid homeostasis by myriocin, a mycotoxin, reduces thymic and splenic T-lymphocyte populations. Toxicology. 2004 Sep 1;201(1-3):67-75. PMID: 15297021.

" Xn "UN number: 2811     Class:  6.1     Packing group:  III

Proper shipping name:  Toxic solids, organic, n.o.s. (Myriocin from Mycelia sterilia)

Marine pollutant:  No     Poison inhalation hazard:  No"

LKT M9643 Myelin Basic Protein (1-11), human 1 mg 29.9 106128-98-7 ≥95% 1293.42 C52H88N22O17 Ambient -20°C "Buenafe AC, Sherwood C, Moes N, et al. Recombinase-activating gene 1-associated expression of the myelin basic protein 1-11-specific transgenic T-cell receptor in H-2b mice. J Neurosci Res. 2009 Jan;87(1):42-9. PMID: 18752298.

Zhang GX, Xu H, Kishi M, et al. The role of IL-12 in the induction of intravenous tolerance in experimental autoimmune encephalomyelitis. J Immunol. 2002 Mar 1;168(5):2501-7. PMID: 11859144.

" Not dangerous goods.

LKT M9643 Myelin Basic Protein (1-11), human 2 mg 204.1 106128-98-7 ≥95% 1293.42 C52H88N22O17 Ambient -20°C "Buenafe AC, Sherwood C, Moes N, et al. Recombinase-activating gene 1-associated expression of the myelin basic protein 1-11-specific transgenic T-cell receptor in H-2b mice. J Neurosci Res. 2009 Jan;87(1):42-9. PMID: 18752298.

Zhang GX, Xu H, Kishi M, et al. The role of IL-12 in the induction of intravenous tolerance in experimental autoimmune encephalomyelitis. J Immunol. 2002 Mar 1;168(5):2501-7. PMID: 11859144.

" Not dangerous goods.

LKT M9643 Myelin Basic Protein (1-11), human 5 mg 359.9 106128-98-7 ≥95% 1293.42 C52H88N22O17 Ambient -20°C "Buenafe AC, Sherwood C, Moes N, et al. Recombinase-activating gene 1-associated expression of the myelin basic protein 1-11-specific transgenic T-cell receptor in H-2b mice. J Neurosci Res. 2009 Jan;87(1):42-9. PMID: 18752298.

Zhang GX, Xu H, Kishi M, et al. The role of IL-12 in the induction of intravenous tolerance in experimental autoimmune encephalomyelitis. J Immunol. 2002 Mar 1;168(5):2501-7. PMID: 11859144.

" Not dangerous goods.

LKT M9644 Myelin Basic Protein (87-99), guinea pig/human 1 mg 120 Immunodominant peptide epitope occurring in multiple sclerosis. MBP ≥95% 1555.8 C74H114N20O17 Ambient -20°C "Mantzourani ED, Platts JA, Brancale A, et al. Molecular dynamics at the receptor level of immunodominant myelin basic protein epitope 87-99 implicated in multiple sclerosis and its antagonists altered peptide ligands: triggering of immune response. J Mol Graph Model. 2007 Sep;26(2):471-81. PMID: 17392002.

Liu JQ, Bai XF, Shi FD, et al. Inhibition of experimental autoimmune encephalomyelitis in Lewis rats by nasal administration of encephalitogenic MBP peptides: synergistic effects of MBP 68-86 and 87-99. Int Immunol. 1998 Aug;10(8):1139-48. PMID: 9723700.

" Not dangerous goods.

LKT M9644 Myelin Basic Protein (87-99), guinea pig/human 2 mg 204.1 Immunodominant peptide epitope occurring in multiple sclerosis. MBP ≥95% 1555.8 C74H114N20O17 Ambient -20°C "Mantzourani ED, Platts JA, Brancale A, et al. Molecular dynamics at the receptor level of immunodominant myelin basic protein epitope 87-99 implicated in multiple sclerosis and its antagonists altered peptide ligands: triggering of immune response. J Mol Graph Model. 2007 Sep;26(2):471-81. PMID: 17392002.

Liu JQ, Bai XF, Shi FD, et al. Inhibition of experimental autoimmune encephalomyelitis in Lewis rats by nasal administration of encephalitogenic MBP peptides: synergistic effects of MBP 68-86 and 87-99. Int Immunol. 1998 Aug;10(8):1139-48. PMID: 9723700.

" Not dangerous goods.

LKT M9644 Myelin Basic Protein (87-99), guinea pig/human 5 mg 359.9 Immunodominant peptide epitope occurring in multiple sclerosis. MBP ≥95% 1555.8 C74H114N20O17 Ambient -20°C "Mantzourani ED, Platts JA, Brancale A, et al. Molecular dynamics at the receptor level of immunodominant myelin basic protein epitope 87-99 implicated in multiple sclerosis and its antagonists altered peptide ligands: triggering of immune response. J Mol Graph Model. 2007 Sep;26(2):471-81. PMID: 17392002.

Liu JQ, Bai XF, Shi FD, et al. Inhibition of experimental autoimmune encephalomyelitis in Lewis rats by nasal administration of encephalitogenic MBP peptides: synergistic effects of MBP 68-86 and 87-99. Int Immunol. 1998 Aug;10(8):1139-48. PMID: 9723700.

" Not dangerous goods.

LKT M9645 Myelin Oligodendrocyte Glycoprotein (35-55), rat 1 mg 228 Oligodendrocyte antigen used to induce EAE. MOG (35-55) 163913-87-9 ≥98% 2582 C118H177N35O29S Ambient -20°C "Zhu D, Liu M, Yang Y, et al. Ginsenoside Rd ameliorates experimental autoimmune encephalomyelitis in C57BL/6 mice. J Neurosci Res. 2014 May 2. [Epub ahead of print]. PMID: 24798871.

Sosa RA, Murphey C, Ji N, et al. The kinetics of myelin antigen uptake by myeloid cells in the central nervous system during experimental autoimmune encephalomyelitis. J Immunol. 2013 Dec 15;191(12):5848-57. PMID: 24227784.

" Not dangerous goods.

LKT M9645 Myelin Oligodendrocyte Glycoprotein (35-55), rat 2 mg 387 Oligodendrocyte antigen used to induce EAE. MOG (35-55) 163913-87-9 ≥98% 2582 C118H177N35O29S Ambient -20°C "Zhu D, Liu M, Yang Y, et al. Ginsenoside Rd ameliorates experimental autoimmune encephalomyelitis in C57BL/6 mice. J Neurosci Res. 2014 May 2. [Epub ahead of print]. PMID: 24798871.

Sosa RA, Murphey C, Ji N, et al. The kinetics of myelin antigen uptake by myeloid cells in the central nervous system during experimental autoimmune encephalomyelitis. J Immunol. 2013 Dec 15;191(12):5848-57. PMID: 24227784.

" Not dangerous goods.

LKT M9645 Myelin Oligodendrocyte Glycoprotein (35-55), rat 5 mg 684.1 Oligodendrocyte antigen used to induce EAE. MOG (35-55) 163913-87-9 ≥98% 2582 C118H177N35O29S Ambient -20°C "Zhu D, Liu M, Yang Y, et al. Ginsenoside Rd ameliorates experimental autoimmune encephalomyelitis in C57BL/6 mice. J Neurosci Res. 2014 May 2. [Epub ahead of print]. PMID: 24798871.

Sosa RA, Murphey C, Ji N, et al. The kinetics of myelin antigen uptake by myeloid cells in the central nervous system during experimental autoimmune encephalomyelitis. J Immunol. 2013 Dec 15;191(12):5848-57. PMID: 24227784.

" Not dangerous goods.

LKT M9646 Myelin Basic Protein (68-82), guinea pig 1 mg 120 Immunodominant peptide epitope occurring in multiple sclerosis. MBP ≥95% 1736.8 C71H113N23O28 Ambient -20°C "Mantzourani ED, Platts JA, Brancale A, et al. Molecular dynamics at the receptor level of immunodominant myelin basic protein epitope 87-99 implicated in multiple sclerosis and its antagonists altered peptide ligands: triggering of immune response. J Mol Graph Model. 2007 Sep;26(2):471-81. PMID: 17392002.

Liu JQ, Bai XF, Shi FD, et al. Inhibition of experimental autoimmune encephalomyelitis in Lewis rats by nasal administration of encephalitogenic MBP peptides: synergistic effects of MBP 68-86 and 87-99. Int Immunol. 1998 Aug;10(8):1139-48. PMID: 9723700.

" Not dangerous goods.

LKT M9646 Myelin Basic Protein (68-82), guinea pig 2 mg 204.1 Immunodominant peptide epitope occurring in multiple sclerosis. MBP ≥95% 1736.8 C71H113N23O28 Ambient -20°C "Mantzourani ED, Platts JA, Brancale A, et al. Molecular dynamics at the receptor level of immunodominant myelin basic protein epitope 87-99 implicated in multiple sclerosis and its antagonists altered peptide ligands: triggering of immune response. J Mol Graph Model. 2007 Sep;26(2):471-81. PMID: 17392002.

Liu JQ, Bai XF, Shi FD, et al. Inhibition of experimental autoimmune encephalomyelitis in Lewis rats by nasal administration of encephalitogenic MBP peptides: synergistic effects of MBP 68-86 and 87-99. Int Immunol. 1998 Aug;10(8):1139-48. PMID: 9723700.

" Not dangerous goods.

LKT M9646 Myelin Basic Protein (68-82), guinea pig 5 mg 359.9 Immunodominant peptide epitope occurring in multiple sclerosis. MBP ≥95% 1736.8 C71H113N23O28 Ambient -20°C "Mantzourani ED, Platts JA, Brancale A, et al. Molecular dynamics at the receptor level of immunodominant myelin basic protein epitope 87-99 implicated in multiple sclerosis and its antagonists altered peptide ligands: triggering of immune response. J Mol Graph Model. 2007 Sep;26(2):471-81. PMID: 17392002.

Liu JQ, Bai XF, Shi FD, et al. Inhibition of experimental autoimmune encephalomyelitis in Lewis rats by nasal administration of encephalitogenic MBP peptides: synergistic effects of MBP 68-86 and 87-99. Int Immunol. 1998 Aug;10(8):1139-48. PMID: 9723700.

" Not dangerous goods.

LKT M9710 Mycophenolic Acid 50 mg 54.4 Phthalide; PPARγ agonist, IMPDH inhibitor, microtubule polymerization inhibitor. 24280-93-1 ≥98% 320.34 C17H20O6 CC1=C(C(=C(C2=C1COC2=O)O)CC=C(C)CCC(=O)O)OC Ambient Ambient DMSO, Ethanol, Methanol, DCM. Insoluble in water "Rinaldelli E, Panattoni A, Luvisi A, et al. Effect of mycophenolic acid on trans-plasma membrane electron transport and electric potential in virus-infected plant tissue. Plant Physiol Biochem. 2012 Nov;60:137-40. PMID: 22935477.

Eickenberg S, Mickholz E, Jung E, et al. Mycophenolic acid counteracts B cell proliferation and plasmablast formation in patients with systemic lupus erythematosus. Arthritis Res Ther. 2012;14(3):R110. PMID: 22571761.

Zheng ZH, Yang Y, Lu XH, et al. Mycophenolic acid induces adipocyte-like differentiation and reversal of malignancy of breast cancer cells partly through PPARγ. Eur J Pharmacol. 2011 May 1;658(1):1-8. PMID: 21349264.

Huh KH, Ahn HJ, Park J, et al. Mycophenolic acid inhibits oleic acid-induced mesangial cell activation through both cellular reactive oxygen species and inosine monophosphate dehydrogenase 2 pathways. Pediatr Nephrol. 2009 Apr;24(4):737-45. PMID: 19093139.

Chaigne-Delalande B, Guidicelli G, Couzi L, et al. The immunosuppressor mycophenolic acid kills activated lymphocytes by inducing a nonclassical actin-dependent necrotic signal. J Immunol. 2008 Dec 1;181(11):7630-8. PMID: 19017951.

" T, N Not dangerous goods.

LKT M9710 Mycophenolic Acid 250 mg 169.9 Phthalide; PPARγ agonist, IMPDH inhibitor, microtubule polymerization inhibitor. 24280-93-1 ≥98% 320.34 C17H20O6 CC1=C(C(=C(C2=C1COC2=O)O)CC=C(C)CCC(=O)O)OC Ambient Ambient DMSO, Ethanol, Methanol, DCM. Insoluble in water "Rinaldelli E, Panattoni A, Luvisi A, et al. Effect of mycophenolic acid on trans-plasma membrane electron transport and electric potential in virus-infected plant tissue. Plant Physiol Biochem. 2012 Nov;60:137-40. PMID: 22935477.

Eickenberg S, Mickholz E, Jung E, et al. Mycophenolic acid counteracts B cell proliferation and plasmablast formation in patients with systemic lupus erythematosus. Arthritis Res Ther. 2012;14(3):R110. PMID: 22571761.

Zheng ZH, Yang Y, Lu XH, et al. Mycophenolic acid induces adipocyte-like differentiation and reversal of malignancy of breast cancer cells partly through PPARγ. Eur J Pharmacol. 2011 May 1;658(1):1-8. PMID: 21349264.

Huh KH, Ahn HJ, Park J, et al. Mycophenolic acid inhibits oleic acid-induced mesangial cell activation through both cellular reactive oxygen species and inosine monophosphate dehydrogenase 2 pathways. Pediatr Nephrol. 2009 Apr;24(4):737-45. PMID: 19093139.

Chaigne-Delalande B, Guidicelli G, Couzi L, et al. The immunosuppressor mycophenolic acid kills activated lymphocytes by inducing a nonclassical actin-dependent necrotic signal. J Immunol. 2008 Dec 1;181(11):7630-8. PMID: 19017951.

" T, N Not dangerous goods.

LKT S0831 S-(−)-Schisandrin B 5 mg 134.1 Found in Schisandra. "Benzo(3,4)cycloocta(1,2-f)(1,3)benzodioxole, 5,6,7,8-

tetrahydro-1,2,3,13-tetramethoxy-6,7-dimethyl-, stereoisomer" γ-Schisandrin; S(-) Wuweizisu B; S(-) Schizandrin B 61281-37-6 ≥98% 400.47 C23H28O6 CC1CC2=CC3=C(C(=C2C4=C(C(=C(C=C4CC1C)OC)OC)OC)OC)OCO3 Ambient 4°C [α]D: -51° (c=0.15, CHCl3) "Chun JN, Kim SY, Park EJ, et al. Schisandrin B suppresses TGFβ1-induced stress fiber formation by inhibiting myosin light chain phosphorylation. J Ethnopharmacol. 2014 Mar 14;152(2):364-71. PMID: 24486209.

Li L, Zhang T, Zhou L, et al. Schisandrin B attenuates acetaminophen-induced hepatic injury through heat-shock protein 27 and 70 in mice. J Gastroenterol Hepatol. 2014 Mar;29(3):640-7. PMID: 24219791.

Chen P, Pang S, Yang N, et al. Beneficial effects of schisandrin B on the cardiac function in mice model of myocardial infarction. PLoS One. 2013 Nov 8;8(11):e79418. PMID: 24260217.

Lee TH, Jung CH, Lee DH. Neuroprotective effects of Schisandrin B against transient focal cerebral ischemia in Sprague-Dawley rats. Food Chem Toxicol. 2012 Dec;50(12):4239-45. PMID: 22960133.

Liu Z, Zhang B, Liu K, et al. Schisandrin B attenuates cancer invasion and metastasis via inhibiting epithelial-mesenchymal transition. PLoS One. 2012;7(7):e40480. PMID: 22848381.

" Not dangerous goods.

LKT S0831 S-(−)-Schisandrin B 10 mg 219.7 Found in Schisandra. "Benzo(3,4)cycloocta(1,2-f)(1,3)benzodioxole, 5,6,7,8-

tetrahydro-1,2,3,13-tetramethoxy-6,7-dimethyl-, stereoisomer" γ-Schisandrin; S(-) Wuweizisu B; S(-) Schizandrin B 61281-37-6 ≥98% 400.47 C23H28O6 CC1CC2=CC3=C(C(=C2C4=C(C(=C(C=C4CC1C)OC)OC)OC)OC)OCO3 Ambient 4°C [α]D: -51° (c=0.15, CHCl3) "Chun JN, Kim SY, Park EJ, et al. Schisandrin B suppresses TGFβ1-induced stress fiber formation by inhibiting myosin light chain phosphorylation. J Ethnopharmacol. 2014 Mar 14;152(2):364-71. PMID: 24486209.

Li L, Zhang T, Zhou L, et al. Schisandrin B attenuates acetaminophen-induced hepatic injury through heat-shock protein 27 and 70 in mice. J Gastroenterol Hepatol. 2014 Mar;29(3):640-7. PMID: 24219791.

Chen P, Pang S, Yang N, et al. Beneficial effects of schisandrin B on the cardiac function in mice model of myocardial infarction. PLoS One. 2013 Nov 8;8(11):e79418. PMID: 24260217.

Lee TH, Jung CH, Lee DH. Neuroprotective effects of Schisandrin B against transient focal cerebral ischemia in Sprague-Dawley rats. Food Chem Toxicol. 2012 Dec;50(12):4239-45. PMID: 22960133.

Liu Z, Zhang B, Liu K, et al. Schisandrin B attenuates cancer invasion and metastasis via inhibiting epithelial-mesenchymal transition. PLoS One. 2012;7(7):e40480. PMID: 22848381.

" Not dangerous goods.

LKT S0830 R-(+)-Schisandrin A 5 mg 134.1 Found in Schisandra. "Dibenzo(a,c)cyclooctene, 5,6,7,8-tetrahydro-1,2,3,10,11,12-

hexamethoxy-6,7-dimethyl-, stereoisomer" R(+) Schizandrin A; R(+) deoxyschisandrin A; R(+) deoxyschizandrin 61281-38-7 ≥98% 416.51 C24H32O6 CC1CC2=CC(=C(C(=C2C3=C(C(=C(C=C3CC1C)OC)OC)OC)OC)OC)OC Ambient 4°C [α]D: +110° (c=1.15, CHCl3) "Chang R, Li Y, Yang X, et al. Protective role of deoxyschizandrin and schisantherin A against myocardial ischemia-reperfusion injury in rats. PLoS One. 2013 Apr 19;8(4):e61590. PMID: 23620773.

Yang X, Wang Y, Zhang X, et al. Screening vasoconstriction inhibitors from traditional Chinese medicines using a vascular smooth muscle/cell membrane chromatography-offline-liquid chromatography-mass spectrometry. J Sep Sci. 2011 Oct;34(19):2586-93. PMID: 21898806.

" Not dangerous goods.

LKT O0829 Ochratoxin A 1 mg 90.2 Mycotoxin produced by Aspergillus and Penicillum; carcinogen. (R)-N-[(5-Chloro-3,4-dihydro-8-hydroxy-3-methyl-1- oxo-1H-2benzopyran-7-yl)carbonyl]-L-phenylalanine Phenylalanine - ochratoxin A 303-47-9 ≥98% 403.82 C20H18ClNO6 CC1CC2=C(C=C(C(=C2C(=O)O1)O)C(=O)NC(CC3=CC=CC=C3)C(=O)O)Cl Ambient -20°C Soluble in methanol. "Hennemeier I, Humpf HU, Gekle M, et al. Role of microRNA-29b in the ochratoxin A-induced enhanced collagen formation in human kidney cells. Toxicology. 2014 Oct 3;324:116-22. PMID: 25091173.

Paradells S, Rocamonde B, Llinares C, et al. Neurotoxic effects of ochratoxin A on the subventricular zone of adult mouse brain. J Appl Toxicol. 2014 Sep 25. [Epub ahead of print]. PMID: 25256750.

Qi X, Yu T, Zhu L, et al. Ochratoxin A induces rat renal carcinogenicity with limited induction of oxidative stress responses. Toxicol Appl Pharmacol. 2014 Sep 8. [Epub ahead of print]. PMID: 25218026.

Wu X, Hu J, Zhu B, et al. Aptamer-targeted magnetic nanospheres as a solid-phase extraction sorbent for determination of ochratoxin A in food samples. J Chromatogr A. 2011 Oct 14;1218(41):7341-7346. PMID: 21890142.

" T+ "UN number: 3462     Class: 6.1     Packing Group: II

Proper shipping name: Toxins, extracted from living sources, solid, n.o.s. (Ochratoxin A)"

LKT O0829 Ochratoxin A 5 mg 392.5 Mycotoxin produced by Aspergillus and Penicillum; carcinogen. (R)-N-[(5-Chloro-3,4-dihydro-8-hydroxy-3-methyl-1- oxo-1H-2benzopyran-7-yl)carbonyl]-L-phenylalanine Phenylalanine - ochratoxin A 303-47-9 ≥98% 403.82 C20H18ClNO6 CC1CC2=C(C=C(C(=C2C(=O)O1)O)C(=O)NC(CC3=CC=CC=C3)C(=O)O)Cl Ambient -20°C Soluble in methanol. "Hennemeier I, Humpf HU, Gekle M, et al. Role of microRNA-29b in the ochratoxin A-induced enhanced collagen formation in human kidney cells. Toxicology. 2014 Oct 3;324:116-22. PMID: 25091173.

Paradells S, Rocamonde B, Llinares C, et al. Neurotoxic effects of ochratoxin A on the subventricular zone of adult mouse brain. J Appl Toxicol. 2014 Sep 25. [Epub ahead of print]. PMID: 25256750.

Qi X, Yu T, Zhu L, et al. Ochratoxin A induces rat renal carcinogenicity with limited induction of oxidative stress responses. Toxicol Appl Pharmacol. 2014 Sep 8. [Epub ahead of print]. PMID: 25218026.

Wu X, Hu J, Zhu B, et al. Aptamer-targeted magnetic nanospheres as a solid-phase extraction sorbent for determination of ochratoxin A in food samples. J Chromatogr A. 2011 Oct 14;1218(41):7341-7346. PMID: 21890142.

" T+ "UN number: 3462     Class: 6.1     Packing Group: II

Proper shipping name: Toxins, extracted from living sources, solid, n.o.s. (Ochratoxin A)"

LKT S0830 R-(+)-Schisandrin A 10 mg 219.7 Found in Schisandra. "Dibenzo(a,c)cyclooctene, 5,6,7,8-tetrahydro-1,2,3,10,11,12-

hexamethoxy-6,7-dimethyl-, stereoisomer" R(+) Schizandrin A; R(+) deoxyschisandrin A; R(+) deoxyschizandrin 61281-38-7 ≥98% 416.51 C24H32O6 CC1CC2=CC(=C(C(=C2C3=C(C(=C(C=C3CC1C)OC)OC)OC)OC)OC)OC Ambient 4°C [α]D: +110° (c=1.15, CHCl3) "Chang R, Li Y, Yang X, et al. Protective role of deoxyschizandrin and schisantherin A against myocardial ischemia-reperfusion injury in rats. PLoS One. 2013 Apr 19;8(4):e61590. PMID: 23620773.

Yang X, Wang Y, Zhang X, et al. Screening vasoconstriction inhibitors from traditional Chinese medicines using a vascular smooth muscle/cell membrane chromatography-offline-liquid chromatography-mass spectrometry. J Sep Sci. 2011 Oct;34(19):2586-93. PMID: 21898806.

" Not dangerous goods.

LKT S0381 Sauvagine 0.5 mg 372.1 CRF-related peptide found in amphibians. Sauvagin 74434-59-6 ≥98% 4599.4 C202H347N56O63S CCC(C)C(C(=O)N)NC(=O)C(C(C)O)NC(=O)C(CC(=O)O)NC(=O)C(CC(C)C)NC(=O)C(CC(C)C)NC(=O)C(CC(C)C)NC(=O)C(CCCNC(=N)N)NC(=O)C(CC(=O)N)NC(=O)C(CC(=O)N)NC(=O)C(C)NC(=O)C(C)NC(=O)C(CCC(=O)N)NC(=O)C(CCC(=O)N)NC(=O)C(CCCCN)NC(=O)C(CCC(=O)O)NC(=O)C(CCCCN)NC(=O)C(CCC(=O)O)NC(=O)C(CCC(=O)N)NC(=O)C(CCCCN)NC(=O)C(CCC(=O)O)NC(=O)C(C(C)CC)NC(=O)C(CCC(=O)O)NC(=O)C(C(C)CC)NC(=O)C(CCSC)NC(=O)C(CCCCN)NC(=O)C(CCCNC(=N)N)NC(=O)C(CC(C)C)NC(=O)C(CC(C)C)NC(=O)C(CCC(=O)O)NC(=O)C(CC(C)C)NC(=O)C(CO)NC(=O)C(CC(C)C)NC(=O)C(CC(=O)O)NC(=O)C(C(C)CC)NC(=O)C(CO)NC(=O)C(C(C)CC)NC(=O)C1CCCN1C(=O)C2CCCN2C(=O)CNC(=O)C3CCC(=O)N3 Ambient -20°C Soluble in water. "Lovejoy DA, Balment RJ. Evolution and physiology of the corticotropin-releasing factor (CRF) family of neuropeptides in vertebrates. Gen Comp Endocrinol. 1999 Jul;115(1):1-22. PMID: 10375459.

Barker DM, Corder R. Studies of the role of endothelium-dependent nitric oxide release in the sustained vasodilator effects of corticotrophin releasing factor and sauvagine. Br J Pharmacol. 1999 Jan;126(1):317-25. PMID: 10051151.

Onali P, Olianas MC. CRF-like effects of sauvagine and urotensin I on synaptosomal tyrosine hydroxylase activity of mouse striatum. Brain Res. 1990 Sep 3;526(2):181-5. PMID: 1979515.

" Not dangerous goods.

LKT S0381 Sauvagine 1 mg 633 CRF-related peptide found in amphibians. Sauvagin 74434-59-6 ≥98% 4599.4 C202H347N56O63S CCC(C)C(C(=O)N)NC(=O)C(C(C)O)NC(=O)C(CC(=O)O)NC(=O)C(CC(C)C)NC(=O)C(CC(C)C)NC(=O)C(CC(C)C)NC(=O)C(CCCNC(=N)N)NC(=O)C(CC(=O)N)NC(=O)C(CC(=O)N)NC(=O)C(C)NC(=O)C(C)NC(=O)C(CCC(=O)N)NC(=O)C(CCC(=O)N)NC(=O)C(CCCCN)NC(=O)C(CCC(=O)O)NC(=O)C(CCCCN)NC(=O)C(CCC(=O)O)NC(=O)C(CCC(=O)N)NC(=O)C(CCCCN)NC(=O)C(CCC(=O)O)NC(=O)C(C(C)CC)NC(=O)C(CCC(=O)O)NC(=O)C(C(C)CC)NC(=O)C(CCSC)NC(=O)C(CCCCN)NC(=O)C(CCCNC(=N)N)NC(=O)C(CC(C)C)NC(=O)C(CC(C)C)NC(=O)C(CCC(=O)O)NC(=O)C(CC(C)C)NC(=O)C(CO)NC(=O)C(CC(C)C)NC(=O)C(CC(=O)O)NC(=O)C(C(C)CC)NC(=O)C(CO)NC(=O)C(C(C)CC)NC(=O)C1CCCN1C(=O)C2CCCN2C(=O)CNC(=O)C3CCC(=O)N3 Ambient -20°C Soluble in water. "Lovejoy DA, Balment RJ. Evolution and physiology of the corticotropin-releasing factor (CRF) family of neuropeptides in vertebrates. Gen Comp Endocrinol. 1999 Jul;115(1):1-22. PMID: 10375459.

Barker DM, Corder R. Studies of the role of endothelium-dependent nitric oxide release in the sustained vasodilator effects of corticotrophin releasing factor and sauvagine. Br J Pharmacol. 1999 Jan;126(1):317-25. PMID: 10051151.

Onali P, Olianas MC. CRF-like effects of sauvagine and urotensin I on synaptosomal tyrosine hydroxylase activity of mouse striatum. Brain Res. 1990 Sep 3;526(2):181-5. PMID: 1979515.

" Not dangerous goods.

LKT S0381 Sauvagine 2.5 mg 1116.2 CRF-related peptide found in amphibians. Sauvagin 74434-59-6 ≥98% 4599.4 C202H347N56O63S CCC(C)C(C(=O)N)NC(=O)C(C(C)O)NC(=O)C(CC(=O)O)NC(=O)C(CC(C)C)NC(=O)C(CC(C)C)NC(=O)C(CC(C)C)NC(=O)C(CCCNC(=N)N)NC(=O)C(CC(=O)N)NC(=O)C(CC(=O)N)NC(=O)C(C)NC(=O)C(C)NC(=O)C(CCC(=O)N)NC(=O)C(CCC(=O)N)NC(=O)C(CCCCN)NC(=O)C(CCC(=O)O)NC(=O)C(CCCCN)NC(=O)C(CCC(=O)O)NC(=O)C(CCC(=O)N)NC(=O)C(CCCCN)NC(=O)C(CCC(=O)O)NC(=O)C(C(C)CC)NC(=O)C(CCC(=O)O)NC(=O)C(C(C)CC)NC(=O)C(CCSC)NC(=O)C(CCCCN)NC(=O)C(CCCNC(=N)N)NC(=O)C(CC(C)C)NC(=O)C(CC(C)C)NC(=O)C(CCC(=O)O)NC(=O)C(CC(C)C)NC(=O)C(CO)NC(=O)C(CC(C)C)NC(=O)C(CC(=O)O)NC(=O)C(C(C)CC)NC(=O)C(CO)NC(=O)C(C(C)CC)NC(=O)C1CCCN1C(=O)C2CCCN2C(=O)CNC(=O)C3CCC(=O)N3 Ambient -20°C Soluble in water. "Lovejoy DA, Balment RJ. Evolution and physiology of the corticotropin-releasing factor (CRF) family of neuropeptides in vertebrates. Gen Comp Endocrinol. 1999 Jul;115(1):1-22. PMID: 10375459.

Barker DM, Corder R. Studies of the role of endothelium-dependent nitric oxide release in the sustained vasodilator effects of corticotrophin releasing factor and sauvagine. Br J Pharmacol. 1999 Jan;126(1):317-25. PMID: 10051151.

Onali P, Olianas MC. CRF-like effects of sauvagine and urotensin I on synaptosomal tyrosine hydroxylase activity of mouse striatum. Brain Res. 1990 Sep 3;526(2):181-5. PMID: 1979515.

" Not dangerous goods.

LKT S0368 Sarcophine 10 mg 234.8 Cembranoid diterpene found in Sarcophyton glaucum. 55038-27-2 ≥98% 316.43 C20H28O3 CC1=CCCC2(C(O2)CCC(=CC3C(=C(C(=O)O3)C)CC1)C)C Ambient -20°C "Szymanski PT, Ahmed SA, Khalifa S, et al. Chemopreventive effect of sarcophine-diol on NOR-1-induced TPA-promoted skin carcinogenesis in female HOS:HR-1 mice. Nat Prod Commun. 2013 Feb;8(2):153-4. PMID: 23513714.

Szymanski PT, Muley P, Ahmed SA, et al. Sarcophine-diol inhibits expression of COX-2, inhibits activity of cPLA2, enhances degradation of PLA2 and PLC(γ)1 and inhibits cell membrane permeability in mouse melanoma B16F10 cells. Mar Drugs. 2012 Oct;10(10):2166-80. PMID: 23170076.

Hassan HM, Sallam AA, Mohammed R, et al. Semisynthetic analogues of the marine cembranoid sarcophine as prostate and breast cancer migration inhibitors. Bioorg Med Chem. 2011 Aug 15;19(16):4928-34. PMID: 21775154.

Erman A, Neéman I. Inhibition of phosphofructokinase by the toxic cembranolide sarcophine isolated from the soft-bodied coral Sarcophyton glaucum. Toxicon. 1977;15(3):207-15.  PMID: 17178.

" Not dangerous goods.

LKT O0977 Octopamine Hydrochloride 1 g 40.7 Endogenous biogenic amine, norepinephrine-like neurotransmitter, also found in various plant sources; potential α/β-adrenergic agonist. "DL-α-(Aminomethyl)-p-hydroxybenzenemethanol

hydrochloride" Epirenor; Norden; Norfen; Norphen. 770-05-8 ≥98% 189.64 C8H11NO2 HCl C1=CC(=CC=C1C(CN)O)O.Cl Stable at room temperature. Ambient Ambient Soluble in water. "Rand D, Knebel D, Ayali A. The effect of octopamine on the locust stomatogastric nervous system. Front Physiol. 2012 Jul 20;3:288. PMID: 22934040.

D'Andrea G, D'Arrigo A, Facchinetti F, et al. Octopamine, unlike other trace amines, inhibits responses of astroglia-enriched cultures to lipopolysaccharide via a β-adrenoreceptor-mediated mechanism. Neurosci Lett. 2012 May 23;517(1):36-40. PMID: 22507691.

Gruntenko NE, Karpova EK, Alekseev AA, et al. Effects of octopamine on reproduction, juvenile hormone metabolism, dopamine, and 20-hydroxyecdysone contents in Drosophila. Arch Insect Biochem Physiol. 2007 Jun;65(2):85-94. PMID: 17523171.

" Xn Not dangerous goods.

LKT O0977 Octopamine Hydrochloride 5 g 101.9 Endogenous biogenic amine, norepinephrine-like neurotransmitter, also found in various plant sources; potential α/β-adrenergic agonist. "DL-α-(Aminomethyl)-p-hydroxybenzenemethanol

hydrochloride" Epirenor; Norden; Norfen; Norphen. 770-05-8 ≥98% 189.64 C8H11NO2 HCl C1=CC(=CC=C1C(CN)O)O.Cl Stable at room temperature. Ambient Ambient Soluble in water. "Rand D, Knebel D, Ayali A. The effect of octopamine on the locust stomatogastric nervous system. Front Physiol. 2012 Jul 20;3:288. PMID: 22934040.

D'Andrea G, D'Arrigo A, Facchinetti F, et al. Octopamine, unlike other trace amines, inhibits responses of astroglia-enriched cultures to lipopolysaccharide via a β-adrenoreceptor-mediated mechanism. Neurosci Lett. 2012 May 23;517(1):36-40. PMID: 22507691.

Gruntenko NE, Karpova EK, Alekseev AA, et al. Effects of octopamine on reproduction, juvenile hormone metabolism, dopamine, and 20-hydroxyecdysone contents in Drosophila. Arch Insect Biochem Physiol. 2007 Jun;65(2):85-94. PMID: 17523171.

" Xn Not dangerous goods.

LKT O0977 Octopamine Hydrochloride 25 g 285.4 Endogenous biogenic amine, norepinephrine-like neurotransmitter, also found in various plant sources; potential α/β-adrenergic agonist. "DL-α-(Aminomethyl)-p-hydroxybenzenemethanol

hydrochloride" Epirenor; Norden; Norfen; Norphen. 770-05-8 ≥98% 189.64 C8H11NO2 HCl C1=CC(=CC=C1C(CN)O)O.Cl Stable at room temperature. Ambient Ambient Soluble in water. "Rand D, Knebel D, Ayali A. The effect of octopamine on the locust stomatogastric nervous system. Front Physiol. 2012 Jul 20;3:288. PMID: 22934040.

D'Andrea G, D'Arrigo A, Facchinetti F, et al. Octopamine, unlike other trace amines, inhibits responses of astroglia-enriched cultures to lipopolysaccharide via a β-adrenoreceptor-mediated mechanism. Neurosci Lett. 2012 May 23;517(1):36-40. PMID: 22507691.

Gruntenko NE, Karpova EK, Alekseev AA, et al. Effects of octopamine on reproduction, juvenile hormone metabolism, dopamine, and 20-hydroxyecdysone contents in Drosophila. Arch Insect Biochem Physiol. 2007 Jun;65(2):85-94. PMID: 17523171.

" Xn Not dangerous goods.

LKT O0978 Octaneuropeptide 1 mg 201.8 Neuropeptide, derivative of DBI. ≥98% 911.1 C41H74N12O11 Ambient -20°C "Leprince J, Oulyadi H, Vaudry D, et al. Synthesis, conformational analysis and biological activity of cyclic analogs of the octadecaneuropeptide ODN. Design of a potent endozepine antagonist. Eur J Biochem. 2001 Dec;268(23):6045-57. PMID: 11732998.

Vezzani A, Serafini R, Stasi MA, et al. Epileptogenic activity of two peptides derived from diazepam binding inhibitor after intrahippocampal injection in rats. Epilepsia. 1991 Sep-Oct;32(5):597-603. PMID: 1655399.

" Not dangerous goods.

LKT S0278 Satraplatin 5 mg 224.3 Pt-based DNA cross-linker. (OC-6-43)-bis(acetato-O)amminedichloro(cyclohexanamine)-platinum Poplat 129580-63-8 ≥98% 498.26 C10H22Cl2N2O4Pt CC(=O)O.CC(=O)O.C1CCC(CC1)N.N.Cl[Pt]Cl Ambient -20°C "Figg WD, Chau CH, Madan RA, et al. Phase II study of satraplatin and prednisone in patients with metastatic castration-resistant prostate cancer: a pharmacogenetic assessment of outcome and toxicity. Clin Genitourin Cancer. 2013 Sep;11(3):229-37. PMID: 23684781.

Kalimutho M, Minutolo A, Grelli S, et al. Satraplatin (JM-216) mediates G2/M cell cycle arrest and potentiates apoptosis via multiple death pathways in colorectal cancer cells thus overcoming platinum chemo-resistance. Cancer Chemother Pharmacol. 2011 Jun;67(6):1299-312. PMID: 20734047.

Yamano Y, Shiiba M, Negoro K, et al. Antitumor activity of satraplatin in cisplatin-resistant oral squamous cell carcinoma cells. Head Neck. 2011 Mar;33(3):309-17. PMID: 20848452.

Fokkema E, Groen HJ, Helder MN, et al. JM216-, JM118-, and cisplatin-induced cytotoxicity in relation to platinum-DNA adduct formation, glutathione levels and p53 status in human tumour cell lines with different sensitivities to cisplatin. Biochem Pharmacol. 2002 Jun 1;63(11):1989-96. PMID: 12093475.

" Not dangerous goods.

LKT S0278 Satraplatin 10 mg 360 Pt-based DNA cross-linker. (OC-6-43)-bis(acetato-O)amminedichloro(cyclohexanamine)-platinum Poplat 129580-63-8 ≥98% 498.26 C10H22Cl2N2O4Pt CC(=O)O.CC(=O)O.C1CCC(CC1)N.N.Cl[Pt]Cl Ambient -20°C "Figg WD, Chau CH, Madan RA, et al. Phase II study of satraplatin and prednisone in patients with metastatic castration-resistant prostate cancer: a pharmacogenetic assessment of outcome and toxicity. Clin Genitourin Cancer. 2013 Sep;11(3):229-37. PMID: 23684781.

Kalimutho M, Minutolo A, Grelli S, et al. Satraplatin (JM-216) mediates G2/M cell cycle arrest and potentiates apoptosis via multiple death pathways in colorectal cancer cells thus overcoming platinum chemo-resistance. Cancer Chemother Pharmacol. 2011 Jun;67(6):1299-312. PMID: 20734047.

Yamano Y, Shiiba M, Negoro K, et al. Antitumor activity of satraplatin in cisplatin-resistant oral squamous cell carcinoma cells. Head Neck. 2011 Mar;33(3):309-17. PMID: 20848452.

Fokkema E, Groen HJ, Helder MN, et al. JM216-, JM118-, and cisplatin-induced cytotoxicity in relation to platinum-DNA adduct formation, glutathione levels and p53 status in human tumour cell lines with different sensitivities to cisplatin. Biochem Pharmacol. 2002 Jun 1;63(11):1989-96. PMID: 12093475.

" Not dangerous goods.

LKT S0278 Satraplatin 50 mg 1155.2 Pt-based DNA cross-linker. (OC-6-43)-bis(acetato-O)amminedichloro(cyclohexanamine)-platinum Poplat 129580-63-8 ≥98% 498.26 C10H22Cl2N2O4Pt CC(=O)O.CC(=O)O.C1CCC(CC1)N.N.Cl[Pt]Cl Ambient -20°C "Figg WD, Chau CH, Madan RA, et al. Phase II study of satraplatin and prednisone in patients with metastatic castration-resistant prostate cancer: a pharmacogenetic assessment of outcome and toxicity. Clin Genitourin Cancer. 2013 Sep;11(3):229-37. PMID: 23684781.

Kalimutho M, Minutolo A, Grelli S, et al. Satraplatin (JM-216) mediates G2/M cell cycle arrest and potentiates apoptosis via multiple death pathways in colorectal cancer cells thus overcoming platinum chemo-resistance. Cancer Chemother Pharmacol. 2011 Jun;67(6):1299-312. PMID: 20734047.

Yamano Y, Shiiba M, Negoro K, et al. Antitumor activity of satraplatin in cisplatin-resistant oral squamous cell carcinoma cells. Head Neck. 2011 Mar;33(3):309-17. PMID: 20848452.

Fokkema E, Groen HJ, Helder MN, et al. JM216-, JM118-, and cisplatin-induced cytotoxicity in relation to platinum-DNA adduct formation, glutathione levels and p53 status in human tumour cell lines with different sensitivities to cisplatin. Biochem Pharmacol. 2002 Jun 1;63(11):1989-96. PMID: 12093475.

" Not dangerous goods.

LKT S0244 Salsalate 25 g 40.7 Salicylic acid prodrug, NSAID; weak COX-1/2 inhibitor. 2-(2-hydroxybenzoyl)oxybenzoic acid 552-94-3 ≥95% 258.23 C14H10O5 C1=CC=C(C(=C1)C(=O)OC2=CC=CC=C2C(=O)O)O Ambient 4°C "Jung TW, Choi HY, Lee SY, et al. Salsalate and Adiponectin Improve Palmitate-Induced Insulin Resistance via Inhibition of Selenoprotein P through the AMPK-FOXO1α Pathway. PLoS One. 2013 Jun 18;8(6):e66529. PMID: 23825542.

Nixon M, Wake DJ, Livingstone DE, et al. Salicylate downregulates 11β-HSD1 expression in adipose tissue in obese mice and in humans, mediating insulin sensitization. Diabetes. 2012 Apr;61(4):790-6. PMID: 22357964.

McCarty MF. Salsalate may have broad utility in the prevention and treatment of vascular disorders and the metabolic syndrome. Med Hypotheses. 2010 Sep;75(3):276-81. PMID: 20080359.

" Xi Not dangerous goods.

LKT S0244 Salsalate 100 g 136 Salicylic acid prodrug, NSAID; weak COX-1/2 inhibitor. 2-(2-hydroxybenzoyl)oxybenzoic acid 552-94-3 ≥95% 258.23 C14H10O5 C1=CC=C(C(=C1)C(=O)OC2=CC=CC=C2C(=O)O)O Ambient 4°C "Jung TW, Choi HY, Lee SY, et al. Salsalate and Adiponectin Improve Palmitate-Induced Insulin Resistance via Inhibition of Selenoprotein P through the AMPK-FOXO1α Pathway. PLoS One. 2013 Jun 18;8(6):e66529. PMID: 23825542.

Nixon M, Wake DJ, Livingstone DE, et al. Salicylate downregulates 11β-HSD1 expression in adipose tissue in obese mice and in humans, mediating insulin sensitization. Diabetes. 2012 Apr;61(4):790-6. PMID: 22357964.

McCarty MF. Salsalate may have broad utility in the prevention and treatment of vascular disorders and the metabolic syndrome. Med Hypotheses. 2010 Sep;75(3):276-81. PMID: 20080359.

" Xi Not dangerous goods.

LKT O1078 Octreotide Acetate 1 mg 81.6 Somatostatin analog, peptide; somatostatin agonist. D-Phenylalanyl-L-cysteinyl-L-phenylalanyl-D- tryptophyl-L-lysyl-L-threonyl-N-[2-hydroxy-1- (hydroxymethyl)propyl]-L-cysteinamide cyclic (2->7)-disulfide acetate (salt) Sandostatin  79517-01-4 ≥98% 1139.36 C49H66N10O10S2 2C2H4O2 CC(C1C(=O)NC(CSSCC(C(=O)NC(C(=O)NC(C(=O)NC(C(=O)N1)CCCCN)CC2=CNC3=CC=CC=C32)CC4=CC=CC=C4)NC(=O)C(CC5=CC=CC=C5)N)C(=O)NC(CO)C(C)O)O Ambient -20°C Soluble in methanol. "Wang S, Bao Z, Liang QM, et al. Octreotide stimulates somatostatin receptor-induced apoptosis of SW480 colon cancer cells by activation of glycogen synthase kinase-3β, A Wnt/β-catenin pathway modulator. Hepatogastroenterology. 2013 Oct;60(127):1639-46. PMID: 24634935.

Wang J, Wang L, Song G, et al. The mechanism through which octreotide inhibits hepatic stellate cell activity. Mol Med Rep. 2013 May;7(5):1559-64. PMID: 23525276.

Tug T, Kara H, Karaoglu A, et al. The effect of octreotide, an analog of somatostatin, on bleomycin-induced interstitial pulmonary fibrosis in rats. Drug Chem Toxicol. 2013 Apr;36(2):181-6. PMID: 22946449.

Zhang Y, Huang W, Li F, et al.  Octreotide for the treatment of systemic lupus erythematosus: clinical effects and an in vitro study on its therapeutic mechanism. Lupus. 2011 Oct;20(11):1172-81. PMID: 21979989.

" Not dangerous goods.

LKT O1078 Octreotide Acetate 5 mg 244.5 Somatostatin analog, peptide; somatostatin agonist. D-Phenylalanyl-L-cysteinyl-L-phenylalanyl-D- tryptophyl-L-lysyl-L-threonyl-N-[2-hydroxy-1- (hydroxymethyl)propyl]-L-cysteinamide cyclic (2->7)-disulfide acetate (salt) Sandostatin  79517-01-4 ≥98% 1139.36 C49H66N10O10S2 2C2H4O2 CC(C1C(=O)NC(CSSCC(C(=O)NC(C(=O)NC(C(=O)NC(C(=O)N1)CCCCN)CC2=CNC3=CC=CC=C32)CC4=CC=CC=C4)NC(=O)C(CC5=CC=CC=C5)N)C(=O)NC(CO)C(C)O)O Ambient -20°C Soluble in methanol. "Wang S, Bao Z, Liang QM, et al. Octreotide stimulates somatostatin receptor-induced apoptosis of SW480 colon cancer cells by activation of glycogen synthase kinase-3β, A Wnt/β-catenin pathway modulator. Hepatogastroenterology. 2013 Oct;60(127):1639-46. PMID: 24634935.

Wang J, Wang L, Song G, et al. The mechanism through which octreotide inhibits hepatic stellate cell activity. Mol Med Rep. 2013 May;7(5):1559-64. PMID: 23525276.

Tug T, Kara H, Karaoglu A, et al. The effect of octreotide, an analog of somatostatin, on bleomycin-induced interstitial pulmonary fibrosis in rats. Drug Chem Toxicol. 2013 Apr;36(2):181-6. PMID: 22946449.

Zhang Y, Huang W, Li F, et al.  Octreotide for the treatment of systemic lupus erythematosus: clinical effects and an in vitro study on its therapeutic mechanism. Lupus. 2011 Oct;20(11):1172-81. PMID: 21979989.

" Not dangerous goods.

LKT S0200 SAMs Peptide 0.5 mg 132 Peptide, analog of AMPK binding site on acetyl-CoA carboxylase. 125911-68-4 ≥95% 1779.18 C74H131N29O18S2 Ambient -20°C "Mohan S, Patel H, Bolinaga1 J, et al. AMP-activated protein kinase regulates L-arginine mediated cellular responses. Nutr Metab (Lond). 2013 May 29;10(1):40. PMID: 23718875.

Woollhead AM, Sivagnanasundaram J, Kalsi KK, et al. Pharmacological activators of AMP-activated protein kinase have different effects on Na+ transport processes across human lung epithelial cells. Br J Pharmacol. 2007 Aug;151(8):1204-15. PMID: 17603555.

Davies SP, Carling D, Hardie DG. Tissue distribution of the AMP-activated protein kinase, and lack of activation by cyclic-AMP-dependent protein kinase, studied using a specific and sensitive peptide assay. Eur J Biochem. 1989 Dec 8;186(1-2):123-8. PMID: 2574667.

" Not dangerous goods.

LKT S0200 SAMs Peptide 1 mg 225 Peptide, analog of AMPK binding site on acetyl-CoA carboxylase. 125911-68-4 ≥95% 1779.18 C74H131N29O18S2 Ambient -20°C "Mohan S, Patel H, Bolinaga1 J, et al. AMP-activated protein kinase regulates L-arginine mediated cellular responses. Nutr Metab (Lond). 2013 May 29;10(1):40. PMID: 23718875.

Woollhead AM, Sivagnanasundaram J, Kalsi KK, et al. Pharmacological activators of AMP-activated protein kinase have different effects on Na+ transport processes across human lung epithelial cells. Br J Pharmacol. 2007 Aug;151(8):1204-15. PMID: 17603555.

Davies SP, Carling D, Hardie DG. Tissue distribution of the AMP-activated protein kinase, and lack of activation by cyclic-AMP-dependent protein kinase, studied using a specific and sensitive peptide assay. Eur J Biochem. 1989 Dec 8;186(1-2):123-8. PMID: 2574667.

" Not dangerous goods.

LKT S0200 SAMs Peptide 2.5 mg 396.1 Peptide, analog of AMPK binding site on acetyl-CoA carboxylase. 125911-68-4 ≥95% 1779.18 C74H131N29O18S2 Ambient -20°C "Mohan S, Patel H, Bolinaga1 J, et al. AMP-activated protein kinase regulates L-arginine mediated cellular responses. Nutr Metab (Lond). 2013 May 29;10(1):40. PMID: 23718875.

Woollhead AM, Sivagnanasundaram J, Kalsi KK, et al. Pharmacological activators of AMP-activated protein kinase have different effects on Na+ transport processes across human lung epithelial cells. Br J Pharmacol. 2007 Aug;151(8):1204-15. PMID: 17603555.

Davies SP, Carling D, Hardie DG. Tissue distribution of the AMP-activated protein kinase, and lack of activation by cyclic-AMP-dependent protein kinase, studied using a specific and sensitive peptide assay. Eur J Biochem. 1989 Dec 8;186(1-2):123-8. PMID: 2574667.

" Not dangerous goods.

LKT O1176 n-Octyl Caffeate 5 mg 46.8 Caffeic acid derivative. Caffeic acid n-octyl ester, 3,4-dihydroxycinnamic acid n-octyl ester. 478392-41-5 ≥98% 292.37 C17H24O4 Ambient 4°C "Nagaoka T, Banskota AH, Tezuka Y, et al. Inhibitory effects of caffeic acid phenethyl ester analogues on experimental lung metastasis of murine colon 26-L5 carcinoma cells. Biol Pharm Bull. 2003 May;26(5):638-41. PMID: 12736504.

Hsiao G, Shen MY, Chang WC, et al. A novel antioxidant, octyl caffeate, suppression of LPS/IFN-gamma-induced inducible nitric oxide synthase gene expression in rat aortic smooth muscle cells. Biochem Pharmacol. 2003 Apr 15;65(8):1383-92. PMID: 12694879.

" Not dangerous goods.

LKT O1176 n-Octyl Caffeate 25 mg 187.4 Caffeic acid derivative. Caffeic acid n-octyl ester, 3,4-dihydroxycinnamic acid n-octyl ester. 478392-41-5 ≥98% 292.37 C17H24O4 Ambient 4°C "Nagaoka T, Banskota AH, Tezuka Y, et al. Inhibitory effects of caffeic acid phenethyl ester analogues on experimental lung metastasis of murine colon 26-L5 carcinoma cells. Biol Pharm Bull. 2003 May;26(5):638-41. PMID: 12736504.

Hsiao G, Shen MY, Chang WC, et al. A novel antioxidant, octyl caffeate, suppression of LPS/IFN-gamma-induced inducible nitric oxide synthase gene expression in rat aortic smooth muscle cells. Biochem Pharmacol. 2003 Apr 15;65(8):1383-92. PMID: 12694879.

" Not dangerous goods.

LKT S0171 Sarafotoxin 6c 0.5 mg 372.1 Isoform of a toxin found in Atractaspis engaddensis; ET-B agonist, ATP-sensitive K+ channel activator. 121695-87-2 ≥95% 2515.8 C103H147N27O37S5 CCC(C)C(C(=O)NC(CC1=CNC2=CC=CC=C21)C(=O)O)NC(=O)C(C(C)C)NC(=O)C(CC(=O)O)NC(=O)C(CCC(=O)N)NC(=O)C(CC3=CN=CN3)NC(=O)C4CSSCC(C(=O)NC(C(=O)NC5CSSCC(C(=O)NC(C(=O)NC(C(=O)NC(C(=O)N4)CC6=CC=CC=C6)CC(=O)N)CC(C)C)NC(=O)C(NC(=O)C(NC(=O)C(NC(=O)C(NC(=O)C(NC(=O)C(NC(=O)C(NC5=O)CC(=O)N)CC(=O)O)CCSC)C(C)O)CC(=O)O)CCC(=O)O)CCC(=O)O)C(C)O)N Ambient -20°C "Li J, Cao YX, Liu Y, et al. Minimally modified LDL upregulates endothelin type B receptors in rat basilar artery. Microvasc Res. 2012 Mar;83(2):178-84. PMID: 22198335.

Föller M, Mahmud H, Qadri SM, et al. Endothelin B receptor stimulation inhibits suicidal erythrocyte death. FASEB J. 2010 Sep;24(9):3351-9. PMID: 20427706.

Tykocki NR, Gariepy CE, Watts SW. Endothelin ET(B) receptors in arteries and veins: multiple actions in the vein. J Pharmacol Exp Ther. 2009 Jun;329(3):875-81. PMID: 19297422.

Li M, Dai X, Watts S, et al. Increased superoxide levels in ganglia and sympathoexcitation are involved in sarafotoxin 6c-induced hypertension. Am J Physiol Regul Integr Comp Physiol. 2008 Nov;295(5):R1546-54. PMID: 18768769.

Das B, Sarkar C, Shankar PR. Pretreatment with sarafotoxin 6c prior to coronary occlusion protects against infarction and arrhythmias via cardiomyocyte mitochondrial K(ATP) channel activation in the intact rabbit heart during ischemia/reperfusion. Cardiovasc Drugs Ther. 2007 Aug;21(4):243-51. PMID: 17520332.

" Xn Not dangerous goods.

LKT O1177 n-Octyl-3,4-Dimethylcaffeate 5 mg 37.5 Methylated derivative of n-octyl-caffeate. 3,4-Dimethylcaffeic acid n-octyl ester; 3,4-dimethoxycinnamic acid n-octyl ester ≥98% 320.42 C19H28O4 Ambient 4°C "Nagaoka T, Banskota AH, Tezuka Y, et al. Inhibitory effects of caffeic acid phenethyl ester analogues on experimental lung metastasis of murine colon 26-L5 carcinoma cells. Biol Pharm Bull. 2003 May;26(5):638-41. PMID: 12736504.

Hsiao G, Shen MY, Chang WC, et al. A novel antioxidant, octyl caffeate, suppression of LPS/IFN-gamma-induced inducible nitric oxide synthase gene expression in rat aortic smooth muscle cells. Biochem Pharmacol. 2003 Apr 15;65(8):1383-92. PMID: 12694879.

" Not dangerous goods.

LKT O1177 n-Octyl-3,4-Dimethylcaffeate 25 mg 149.9 Methylated derivative of n-octyl-caffeate. 3,4-Dimethylcaffeic acid n-octyl ester; 3,4-dimethoxycinnamic acid n-octyl ester ≥98% 320.42 C19H28O4 Ambient 4°C "Nagaoka T, Banskota AH, Tezuka Y, et al. Inhibitory effects of caffeic acid phenethyl ester analogues on experimental lung metastasis of murine colon 26-L5 carcinoma cells. Biol Pharm Bull. 2003 May;26(5):638-41. PMID: 12736504.

Hsiao G, Shen MY, Chang WC, et al. A novel antioxidant, octyl caffeate, suppression of LPS/IFN-gamma-induced inducible nitric oxide synthase gene expression in rat aortic smooth muscle cells. Biochem Pharmacol. 2003 Apr 15;65(8):1383-92. PMID: 12694879.

" Not dangerous goods.

LKT S0171 Sarafotoxin 6c 1 mg 633 Isoform of a toxin found in Atractaspis engaddensis; ET-B agonist, ATP-sensitive K+ channel activator. 121695-87-2 ≥95% 2515.8 C103H147N27O37S5 CCC(C)C(C(=O)NC(CC1=CNC2=CC=CC=C21)C(=O)O)NC(=O)C(C(C)C)NC(=O)C(CC(=O)O)NC(=O)C(CCC(=O)N)NC(=O)C(CC3=CN=CN3)NC(=O)C4CSSCC(C(=O)NC(C(=O)NC5CSSCC(C(=O)NC(C(=O)NC(C(=O)NC(C(=O)N4)CC6=CC=CC=C6)CC(=O)N)CC(C)C)NC(=O)C(NC(=O)C(NC(=O)C(NC(=O)C(NC(=O)C(NC(=O)C(NC(=O)C(NC5=O)CC(=O)N)CC(=O)O)CCSC)C(C)O)CC(=O)O)CCC(=O)O)CCC(=O)O)C(C)O)N Ambient -20°C "Li J, Cao YX, Liu Y, et al. Minimally modified LDL upregulates endothelin type B receptors in rat basilar artery. Microvasc Res. 2012 Mar;83(2):178-84. PMID: 22198335.

Föller M, Mahmud H, Qadri SM, et al. Endothelin B receptor stimulation inhibits suicidal erythrocyte death. FASEB J. 2010 Sep;24(9):3351-9. PMID: 20427706.

Tykocki NR, Gariepy CE, Watts SW. Endothelin ET(B) receptors in arteries and veins: multiple actions in the vein. J Pharmacol Exp Ther. 2009 Jun;329(3):875-81. PMID: 19297422.

Li M, Dai X, Watts S, et al. Increased superoxide levels in ganglia and sympathoexcitation are involved in sarafotoxin 6c-induced hypertension. Am J Physiol Regul Integr Comp Physiol. 2008 Nov;295(5):R1546-54. PMID: 18768769.

Das B, Sarkar C, Shankar PR. Pretreatment with sarafotoxin 6c prior to coronary occlusion protects against infarction and arrhythmias via cardiomyocyte mitochondrial K(ATP) channel activation in the intact rabbit heart during ischemia/reperfusion. Cardiovasc Drugs Ther. 2007 Aug;21(4):243-51. PMID: 17520332.

" Xn Not dangerous goods.

LKT S0171 Sarafotoxin 6c 2.5 mg 1116.2 Isoform of a toxin found in Atractaspis engaddensis; ET-B agonist, ATP-sensitive K+ channel activator. 121695-87-2 ≥95% 2515.8 C103H147N27O37S5 CCC(C)C(C(=O)NC(CC1=CNC2=CC=CC=C21)C(=O)O)NC(=O)C(C(C)C)NC(=O)C(CC(=O)O)NC(=O)C(CCC(=O)N)NC(=O)C(CC3=CN=CN3)NC(=O)C4CSSCC(C(=O)NC(C(=O)NC5CSSCC(C(=O)NC(C(=O)NC(C(=O)NC(C(=O)N4)CC6=CC=CC=C6)CC(=O)N)CC(C)C)NC(=O)C(NC(=O)C(NC(=O)C(NC(=O)C(NC(=O)C(NC(=O)C(NC(=O)C(NC5=O)CC(=O)N)CC(=O)O)CCSC)C(C)O)CC(=O)O)CCC(=O)O)CCC(=O)O)C(C)O)N Ambient -20°C "Li J, Cao YX, Liu Y, et al. Minimally modified LDL upregulates endothelin type B receptors in rat basilar artery. Microvasc Res. 2012 Mar;83(2):178-84. PMID: 22198335.

Föller M, Mahmud H, Qadri SM, et al. Endothelin B receptor stimulation inhibits suicidal erythrocyte death. FASEB J. 2010 Sep;24(9):3351-9. PMID: 20427706.

Tykocki NR, Gariepy CE, Watts SW. Endothelin ET(B) receptors in arteries and veins: multiple actions in the vein. J Pharmacol Exp Ther. 2009 Jun;329(3):875-81. PMID: 19297422.

Li M, Dai X, Watts S, et al. Increased superoxide levels in ganglia and sympathoexcitation are involved in sarafotoxin 6c-induced hypertension. Am J Physiol Regul Integr Comp Physiol. 2008 Nov;295(5):R1546-54. PMID: 18768769.

Das B, Sarkar C, Shankar PR. Pretreatment with sarafotoxin 6c prior to coronary occlusion protects against infarction and arrhythmias via cardiomyocyte mitochondrial K(ATP) channel activation in the intact rabbit heart during ischemia/reperfusion. Cardiovasc Drugs Ther. 2007 Aug;21(4):243-51. PMID: 17520332.

" Xn Not dangerous goods.

LKT O1178 n-Octyl-3-methylcaffeate 5 mg 46.8 Derivative of methyl caffeate, hydroxycinnamic acid. 3-Methylcaffeic acid n-octyl ester; 4-Hydroxy-3-methoxycinnamic acid n-octyl ester ≥98% 306.4 C18H26O4 Ambient 4°C "Nagaoka T, Banskota AH, Tezuka Y, et al. Inhibitory effects of caffeic acid phenethyl ester analogues on experimental lung metastasis of murine colon 26-L5 carcinoma cells. Biol Pharm Bull. 2003 May;26(5):638-41. PMID: 12736504.

Hsiao G, Shen MY, Chang WC, et al. A novel antioxidant, octyl caffeate, suppression of LPS/IFN-gamma-induced inducible nitric oxide synthase gene expression in rat aortic smooth muscle cells. Biochem Pharmacol. 2003 Apr 15;65(8):1383-92. PMID: 12694879.

" Not dangerous goods.

LKT O1178 n-Octyl-3-methylcaffeate 25 mg 187.4 Derivative of methyl caffeate, hydroxycinnamic acid. 3-Methylcaffeic acid n-octyl ester; 4-Hydroxy-3-methoxycinnamic acid n-octyl ester ≥98% 306.4 C18H26O4 Ambient 4°C "Nagaoka T, Banskota AH, Tezuka Y, et al. Inhibitory effects of caffeic acid phenethyl ester analogues on experimental lung metastasis of murine colon 26-L5 carcinoma cells. Biol Pharm Bull. 2003 May;26(5):638-41. PMID: 12736504.

Hsiao G, Shen MY, Chang WC, et al. A novel antioxidant, octyl caffeate, suppression of LPS/IFN-gamma-induced inducible nitric oxide synthase gene expression in rat aortic smooth muscle cells. Biochem Pharmacol. 2003 Apr 15;65(8):1383-92. PMID: 12694879.

" Not dangerous goods.

LKT S0170 Sarafloxacin Hydrochloride 5 g 67.9 Fluoroquinolone; topoisomerase IV and bacterial DNA gyrase inhibitor. 6-Fluoro-1-(4-fluorophenyl)-1,4-dihydro-4-oxo-7-(1-piperazinyl)-3-quinolinecarboxylic acid hydrochloride Abbott 56620; Sarafloxacin monohydrochloride 91296-87-6 ≥91% 421.83 C20H17F2N3O3 HCl C1CN(CCN1)C2=C(C=C3C(=C2)N(C=C(C3=O)C(=O)O)C4=CC=C(C=C4)F)F.Cl Ambient 4°C Soluble in water. "Chansiripornchai N, Sasipreeyajan J. Efficacy of sarafloxacin in broilers after experimental infection with Escherichia coli. Vet Res Commun. 2002 Jun;26(4):255-62. PMID: 12184496.

Wang C, Ewing M, Aarabi SY. In vitro susceptibility of avian mycoplasmas to enrofloxacin, sarafloxacin, tylosin, and oxytetracycline. Avian Dis. 2001 Apr-Jun;45(2):456-60. PMID: 11417828.

" None Not dangerous goods.

LKT S0170 Sarafloxacin Hydrochloride 10 g 115.5 Fluoroquinolone; topoisomerase IV and bacterial DNA gyrase inhibitor. 6-Fluoro-1-(4-fluorophenyl)-1,4-dihydro-4-oxo-7-(1-piperazinyl)-3-quinolinecarboxylic acid hydrochloride Abbott 56620; Sarafloxacin monohydrochloride 91296-87-6 ≥91% 421.83 C20H17F2N3O3 HCl C1CN(CCN1)C2=C(C=C3C(=C2)N(C=C(C3=O)C(=O)O)C4=CC=C(C=C4)F)F.Cl Ambient 4°C Soluble in water. "Chansiripornchai N, Sasipreeyajan J. Efficacy of sarafloxacin in broilers after experimental infection with Escherichia coli. Vet Res Commun. 2002 Jun;26(4):255-62. PMID: 12184496.

Wang C, Ewing M, Aarabi SY. In vitro susceptibility of avian mycoplasmas to enrofloxacin, sarafloxacin, tylosin, and oxytetracycline. Avian Dis. 2001 Apr-Jun;45(2):456-60. PMID: 11417828.

" None Not dangerous goods.

LKT S0170 Sarafloxacin Hydrochloride 25 g 203.8 Fluoroquinolone; topoisomerase IV and bacterial DNA gyrase inhibitor. 6-Fluoro-1-(4-fluorophenyl)-1,4-dihydro-4-oxo-7-(1-piperazinyl)-3-quinolinecarboxylic acid hydrochloride Abbott 56620; Sarafloxacin monohydrochloride 91296-87-6 ≥91% 421.83 C20H17F2N3O3 HCl C1CN(CCN1)C2=C(C=C3C(=C2)N(C=C(C3=O)C(=O)O)C4=CC=C(C=C4)F)F.Cl Ambient 4°C Soluble in water. "Chansiripornchai N, Sasipreeyajan J. Efficacy of sarafloxacin in broilers after experimental infection with Escherichia coli. Vet Res Commun. 2002 Jun;26(4):255-62. PMID: 12184496.

Wang C, Ewing M, Aarabi SY. In vitro susceptibility of avian mycoplasmas to enrofloxacin, sarafloxacin, tylosin, and oxytetracycline. Avian Dis. 2001 Apr-Jun;45(2):456-60. PMID: 11417828.

" None Not dangerous goods.

LKT O1179 n-Octyl-4-methylcaffeate 5 mg 187.4 Derivative of methyl caffeate, hydroxycinnamic acid. 4-Methylcaffeic acid n-octyl ester; 3-Hydroxy-4-methoxycinnamic acid n-octyl ester ≥98% 306.4 C18H26O4 Ambient 4°C "Nagaoka T, Banskota AH, Tezuka Y, et al. Inhibitory effects of caffeic acid phenethyl ester analogues on experimental lung metastasis of murine colon 26-L5 carcinoma cells. Biol Pharm Bull. 2003 May;26(5):638-41. PMID: 12736504.

Hsiao G, Shen MY, Chang WC, et al. A novel antioxidant, octyl caffeate, suppression of LPS/IFN-gamma-induced inducible nitric oxide synthase gene expression in rat aortic smooth muscle cells. Biochem Pharmacol. 2003 Apr 15;65(8):1383-92. PMID: 12694879.

" Not dangerous goods.

LKT O1179 n-Octyl-4-methylcaffeate 25 mg 750.1 Derivative of methyl caffeate, hydroxycinnamic acid. 4-Methylcaffeic acid n-octyl ester; 3-Hydroxy-4-methoxycinnamic acid n-octyl ester ≥98% 306.4 C18H26O4 Ambient 4°C "Nagaoka T, Banskota AH, Tezuka Y, et al. Inhibitory effects of caffeic acid phenethyl ester analogues on experimental lung metastasis of murine colon 26-L5 carcinoma cells. Biol Pharm Bull. 2003 May;26(5):638-41. PMID: 12736504.

Hsiao G, Shen MY, Chang WC, et al. A novel antioxidant, octyl caffeate, suppression of LPS/IFN-gamma-induced inducible nitric oxide synthase gene expression in rat aortic smooth muscle cells. Biochem Pharmacol. 2003 Apr 15;65(8):1383-92. PMID: 12694879.

" Not dangerous goods.

LKT O2144 Ofloxacin 5 g 88.6 Fluoroquinolone; topoisomerase IV and bacterial DNA gyrase inhibitor. "7H-Pyrido(1,2,3-de)-1,4-benzoxazine-6-carboxylic acid, 2,3-

dihydro-9-fluoro-3-methyl-10-(4-methyl-1-piperazinyl)-7-oxo-

, (+-)-" Floxin; Ofloxacin;Tarivid 82419-36-1 ≥98% 361.37 C18H20FN3O4 CC1COC2=C3N1C=C(C(=O)C3=CC(=C2N4CCN(CC4)C)F)C(=O)O Ambient Ambient Slightly soluble in water. "Dwivedi A, Mujtaba SF, Yadav N, et al. Cellular and molecular mechanism of ofloxacin induced apoptotic cell death under ambient UV-A and sunlight exposure. Free Radic Res. 2014 Mar;48(3):333-46. PMID: 24286391.

Pantel A, Petrella S, Matrat S, et al. DNA gyrase inhibition assays are necessary to demonstrate fluoroquinolone resistance secondary to gyrB mutations in Mycobacterium tuberculosis. Antimicrob Agents Chemother. 2011 Oct;55(10):4524-9. PMID: 21768507.

Drlica K, Zhao X. DNA gyrase, topoisomerase IV, and the 4-quinolones. Microbiol Mol Biol Rev. 1997 Sep;61(3):377-92. PMID: 9293187.

" None Not dangerous goods.

LKT O2144 Ofloxacin 10 g 149.9 Fluoroquinolone; topoisomerase IV and bacterial DNA gyrase inhibitor. "7H-Pyrido(1,2,3-de)-1,4-benzoxazine-6-carboxylic acid, 2,3-

dihydro-9-fluoro-3-methyl-10-(4-methyl-1-piperazinyl)-7-oxo-

, (+-)-" Floxin; Ofloxacin;Tarivid 82419-36-1 ≥98% 361.37 C18H20FN3O4 CC1COC2=C3N1C=C(C(=O)C3=CC(=C2N4CCN(CC4)C)F)C(=O)O Ambient Ambient Slightly soluble in water. "Dwivedi A, Mujtaba SF, Yadav N, et al. Cellular and molecular mechanism of ofloxacin induced apoptotic cell death under ambient UV-A and sunlight exposure. Free Radic Res. 2014 Mar;48(3):333-46. PMID: 24286391.

Pantel A, Petrella S, Matrat S, et al. DNA gyrase inhibition assays are necessary to demonstrate fluoroquinolone resistance secondary to gyrB mutations in Mycobacterium tuberculosis. Antimicrob Agents Chemother. 2011 Oct;55(10):4524-9. PMID: 21768507.

Drlica K, Zhao X. DNA gyrase, topoisomerase IV, and the 4-quinolones. Microbiol Mol Biol Rev. 1997 Sep;61(3):377-92. PMID: 9293187.

" None Not dangerous goods.

LKT O2144 Ofloxacin 50 g 593.7 Fluoroquinolone; topoisomerase IV and bacterial DNA gyrase inhibitor. "7H-Pyrido(1,2,3-de)-1,4-benzoxazine-6-carboxylic acid, 2,3-

dihydro-9-fluoro-3-methyl-10-(4-methyl-1-piperazinyl)-7-oxo-

, (+-)-" Floxin; Ofloxacin;Tarivid 82419-36-1 ≥98% 361.37 C18H20FN3O4 CC1COC2=C3N1C=C(C(=O)C3=CC(=C2N4CCN(CC4)C)F)C(=O)O Ambient Ambient Slightly soluble in water. "Dwivedi A, Mujtaba SF, Yadav N, et al. Cellular and molecular mechanism of ofloxacin induced apoptotic cell death under ambient UV-A and sunlight exposure. Free Radic Res. 2014 Mar;48(3):333-46. PMID: 24286391.

Pantel A, Petrella S, Matrat S, et al. DNA gyrase inhibition assays are necessary to demonstrate fluoroquinolone resistance secondary to gyrB mutations in Mycobacterium tuberculosis. Antimicrob Agents Chemother. 2011 Oct;55(10):4524-9. PMID: 21768507.

Drlica K, Zhao X. DNA gyrase, topoisomerase IV, and the 4-quinolones. Microbiol Mol Biol Rev. 1997 Sep;61(3):377-92. PMID: 9293187.

" None Not dangerous goods.

LKT S0168 Saracatinib 1 mg 64.7 Src and Abl inhibitor. N-(5-Chloro-1,3-benzodioxol-4-yl)-7-[2-(4-methyl-1-piperazinyl)ethoxy]-5-[(tetrahydro-2H-pyran-4-yl)oxy]-4-quinazolinamine AZD-0530 379231-04-6 ≥98% 542.03 C27H32ClN5O5 CN1CCN(CC1)CCOC2=CC(=C3C(=C2)N=CN=C3NC4=C(C=CC5=C4OCO5)Cl)OC6CCOCC6 Ambient Ambient "Gangadhar TC, Clark JI, Karrison T, et al. Phase II study of the Src kinase inhibitor saracatinib (AZD0530) in metastatic melanoma. Invest New Drugs. 2013 Jun;31(3):769-73. PMID: 23151808.

Nam HJ, Im SA, Oh DY, et al. Antitumor activity of saracatinib (AZD0530), a c-Src/Abl kinase inhibitor, alone or in combination with chemotherapeutic agents in gastric cancer. Mol Cancer Ther. 2013 Jan;12(1):16-26. PMID: 23144237.

Cavalloni G, Peraldo-Neia C, Sarotto I, et al. Antitumor activity of Src inhibitor saracatinib (AZD-0530) in preclinical models of biliary tract carcinomas. Mol Cancer Ther. 2012 Jul;11(7):1528-38. PMID: 22452946.

Takai S, Sabzevari H, Farsaci B, et al. Distinct effects of saracatinib on memory CD8+ T cell differentiation. J Immunol. 2012 May 1;188(9):4323-33. PMID: 22450814.

" Not dangerous goods.

LKT S0168 Saracatinib 5 mg 213.6 Src and Abl inhibitor. N-(5-Chloro-1,3-benzodioxol-4-yl)-7-[2-(4-methyl-1-piperazinyl)ethoxy]-5-[(tetrahydro-2H-pyran-4-yl)oxy]-4-quinazolinamine AZD-0530 379231-04-6 ≥98% 542.03 C27H32ClN5O5 CN1CCN(CC1)CCOC2=CC(=C3C(=C2)N=CN=C3NC4=C(C=CC5=C4OCO5)Cl)OC6CCOCC6 Ambient Ambient "Gangadhar TC, Clark JI, Karrison T, et al. Phase II study of the Src kinase inhibitor saracatinib (AZD0530) in metastatic melanoma. Invest New Drugs. 2013 Jun;31(3):769-73. PMID: 23151808.

Nam HJ, Im SA, Oh DY, et al. Antitumor activity of saracatinib (AZD0530), a c-Src/Abl kinase inhibitor, alone or in combination with chemotherapeutic agents in gastric cancer. Mol Cancer Ther. 2013 Jan;12(1):16-26. PMID: 23144237.

Cavalloni G, Peraldo-Neia C, Sarotto I, et al. Antitumor activity of Src inhibitor saracatinib (AZD-0530) in preclinical models of biliary tract carcinomas. Mol Cancer Ther. 2012 Jul;11(7):1528-38. PMID: 22452946.

Takai S, Sabzevari H, Farsaci B, et al. Distinct effects of saracatinib on memory CD8+ T cell differentiation. J Immunol. 2012 May 1;188(9):4323-33. PMID: 22450814.

" Not dangerous goods.

LKT S0168 Saracatinib 25 mg 621.2 Src and Abl inhibitor. N-(5-Chloro-1,3-benzodioxol-4-yl)-7-[2-(4-methyl-1-piperazinyl)ethoxy]-5-[(tetrahydro-2H-pyran-4-yl)oxy]-4-quinazolinamine AZD-0530 379231-04-6 ≥98% 542.03 C27H32ClN5O5 CN1CCN(CC1)CCOC2=CC(=C3C(=C2)N=CN=C3NC4=C(C=CC5=C4OCO5)Cl)OC6CCOCC6 Ambient Ambient "Gangadhar TC, Clark JI, Karrison T, et al. Phase II study of the Src kinase inhibitor saracatinib (AZD0530) in metastatic melanoma. Invest New Drugs. 2013 Jun;31(3):769-73. PMID: 23151808.

Nam HJ, Im SA, Oh DY, et al. Antitumor activity of saracatinib (AZD0530), a c-Src/Abl kinase inhibitor, alone or in combination with chemotherapeutic agents in gastric cancer. Mol Cancer Ther. 2013 Jan;12(1):16-26. PMID: 23144237.

Cavalloni G, Peraldo-Neia C, Sarotto I, et al. Antitumor activity of Src inhibitor saracatinib (AZD-0530) in preclinical models of biliary tract carcinomas. Mol Cancer Ther. 2012 Jul;11(7):1528-38. PMID: 22452946.

Takai S, Sabzevari H, Farsaci B, et al. Distinct effects of saracatinib on memory CD8+ T cell differentiation. J Immunol. 2012 May 1;188(9):4323-33. PMID: 22450814.

" Not dangerous goods.

LKT O2145 Ofloxacin Hydrochloride 5 g 76.3 Fluoroquinolone; topoisomerase IV and bacterial DNA gyrase inhibitor. 9-Fluoro-2,3-dihydro-3-methyl-10-(4-methyl-1- piperazinyl)-7-oxo-7H-pyrido[1,2,3-de]-1,4- benzoxazine-6-carboxylic acid Ofloxacin; Exocin; Floxil; Oflocet; Tarivid; Visiren 118120-51-7 ≥98% 397.83 C18H20FN3O4 HCl CC1COC2=C3N1C=C(C(=O)C3=CC(=C2N4CCN(CC4)C)F)C(=O)O.Cl Ambient Ambient Soluble in water. "Dwivedi A, Mujtaba SF, Yadav N, et al. Cellular and molecular mechanism of ofloxacin induced apoptotic cell death under ambient UV-A and sunlight exposure. Free Radic Res. 2014 Mar;48(3):333-46. PMID: 24286391.

Pantel A, Petrella S, Matrat S, et al. DNA gyrase inhibition assays are necessary to demonstrate fluoroquinolone resistance secondary to gyrB mutations in Mycobacterium tuberculosis. Antimicrob Agents Chemother. 2011 Oct;55(10):4524-9. PMID: 21768507.

Drlica K, Zhao X. DNA gyrase, topoisomerase IV, and the 4-quinolones. Microbiol Mol Biol Rev. 1997 Sep;61(3):377-92. PMID: 9293187.

" Xn Not dangerous goods.

LKT O2145 Ofloxacin Hydrochloride 10 g 114.6 Fluoroquinolone; topoisomerase IV and bacterial DNA gyrase inhibitor. 9-Fluoro-2,3-dihydro-3-methyl-10-(4-methyl-1- piperazinyl)-7-oxo-7H-pyrido[1,2,3-de]-1,4- benzoxazine-6-carboxylic acid Ofloxacin; Exocin; Floxil; Oflocet; Tarivid; Visiren 118120-51-7 ≥98% 397.83 C18H20FN3O4 HCl CC1COC2=C3N1C=C(C(=O)C3=CC(=C2N4CCN(CC4)C)F)C(=O)O.Cl Ambient Ambient Soluble in water. "Dwivedi A, Mujtaba SF, Yadav N, et al. Cellular and molecular mechanism of ofloxacin induced apoptotic cell death under ambient UV-A and sunlight exposure. Free Radic Res. 2014 Mar;48(3):333-46. PMID: 24286391.

Pantel A, Petrella S, Matrat S, et al. DNA gyrase inhibition assays are necessary to demonstrate fluoroquinolone resistance secondary to gyrB mutations in Mycobacterium tuberculosis. Antimicrob Agents Chemother. 2011 Oct;55(10):4524-9. PMID: 21768507.

Drlica K, Zhao X. DNA gyrase, topoisomerase IV, and the 4-quinolones. Microbiol Mol Biol Rev. 1997 Sep;61(3):377-92. PMID: 9293187.

" Xn Not dangerous goods.

LKT O2145 Ofloxacin Hydrochloride 50 g 457.6 Fluoroquinolone; topoisomerase IV and bacterial DNA gyrase inhibitor. 9-Fluoro-2,3-dihydro-3-methyl-10-(4-methyl-1- piperazinyl)-7-oxo-7H-pyrido[1,2,3-de]-1,4- benzoxazine-6-carboxylic acid Ofloxacin; Exocin; Floxil; Oflocet; Tarivid; Visiren 118120-51-7 ≥98% 397.83 C18H20FN3O4 HCl CC1COC2=C3N1C=C(C(=O)C3=CC(=C2N4CCN(CC4)C)F)C(=O)O.Cl Ambient Ambient Soluble in water. "Dwivedi A, Mujtaba SF, Yadav N, et al. Cellular and molecular mechanism of ofloxacin induced apoptotic cell death under ambient UV-A and sunlight exposure. Free Radic Res. 2014 Mar;48(3):333-46. PMID: 24286391.

Pantel A, Petrella S, Matrat S, et al. DNA gyrase inhibition assays are necessary to demonstrate fluoroquinolone resistance secondary to gyrB mutations in Mycobacterium tuberculosis. Antimicrob Agents Chemother. 2011 Oct;55(10):4524-9. PMID: 21768507.

Drlica K, Zhao X. DNA gyrase, topoisomerase IV, and the 4-quinolones. Microbiol Mol Biol Rev. 1997 Sep;61(3):377-92. PMID: 9293187.

" Xn Not dangerous goods.

LKT S0134 Saikosaponin D 1 mg 271.7 Triterpene saponin found in Bupleurum. Saikosaponin 20874-52-6 ≥98% 780.98 C42H68O13 CC1C(C(C(C(O1)OC2CCC3(C(C2(C)CO)CCC4(C3C=CC56C4(CC(C7(C5CC(CC7)(C)C)CO6)O)C)C)C)O)OC8C(C(C(C(O8)CO)O)O)O)O Ambient -20°C Soluble in DMSO or methanol. "Zhang BZ, Guo XT, Chen JW, et al. Saikosaponin-D Attenuates Heat Stress-Induced Oxidative Damage in LLC-PK1 Cells by Increasing the Expression of Anti-Oxidant Enzymes and HSP72. Am J Chin Med. 2014 Aug 29:1-17. [Epub ahead of print] PMID: 25169909. 

Ying ZL, Li XJ, Dang H, et al. Saikosaponin-d affects the differentiation, maturation and function of monocyte-derived dendritic cells. Exp Ther Med. 2014 May;7(5):1354-1358. PMID: 24940438.

Wong VK, Li T, Law BY, et al. Saikosaponin-d, a novel SERCA inhibitor, induces autophagic cell death in apoptosis-defective cells. Cell Death Dis. 2013 Jul 11;4:e720. PMID: 23846222.

Lu XL, He SX, Ren MD, et al. Chemopreventive effect of saikosaponin-d on diethylinitrosamine-induced hepatocarcinogenesis: involvement of CCAAT/enhancer binding protein β and cyclooxygenase-2. Mol Med Rep. 2012 Mar;5(3):637-44. PMID: 22159471.

Zheng JX, Lu KQ, Xia DG, et al. Therapeutic effects and mechanism of saikosaponin-d in mice with bleomycin-induced pulmonary fibrosis. Zhonghua Yi Xue Za Zhi. 2010 Mar 30;90(12):808-12. PMID: 20450618.

Wang BF, Cheng YA, Dang SS. Angiogenesis inhibitory effect of saikosaponin-d on chicken embryo. Zhongguo Zhong Xi Yi Jie He Za Zhi. 2009 May;29(5):425-9. PMID: 19673334.

Chiang LC, Ng LT, Liu LT, et al. Cytotoxicity and anti-hepatitis B virus activities of saikosaponins from Bupleurum species. Planta Med. 2003 Aug;69(8):705-9. PMID: 14531019.

" Xi Not dangerous goods.

LKT O2146 R-(+)-Ofloxacin 1 mg 150.4 Fluoroquinolone, optically active isomer of ofloxacin; topoisomerase IV and bacterial DNA gyrase inhibitor. (R)-9-Fluoro-2,3-dihydro-3-methyl-10-(4-methyl-1- piperazinyl)-7-oxo-7H-pyrido[1,2,3-de]-1,4-benz- oxazine-6-carboxylic acid 100986-86-5 ≥98% 361.37 C18H20FN3O4 CC1COC2=C3N1C=C(C(=O)C3=CC(=C2N4CCN(CC4)C)F)C(=O)O Ambient Ambient [α]22D (c=0.5, MeOH) +120 "Dwivedi A, Mujtaba SF, Yadav N, et al. Cellular and molecular mechanism of ofloxacin induced apoptotic cell death under ambient UV-A and sunlight exposure. Free Radic Res. 2014 Mar;48(3):333-46. PMID: 24286391.

Pantel A, Petrella S, Matrat S, et al. DNA gyrase inhibition assays are necessary to demonstrate fluoroquinolone resistance secondary to gyrB mutations in Mycobacterium tuberculosis. Antimicrob Agents Chemother. 2011 Oct;55(10):4524-9. PMID: 21768507.

Drlica K, Zhao X. DNA gyrase, topoisomerase IV, and the 4-quinolones. Microbiol Mol Biol Rev. 1997 Sep;61(3):377-92. PMID: 9293187.

" Not dangerous goods.

LKT S0134 Saikosaponin D 5 mg 543.6 Triterpene saponin found in Bupleurum. Saikosaponin 20874-52-6 ≥98% 780.98 C42H68O13 CC1C(C(C(C(O1)OC2CCC3(C(C2(C)CO)CCC4(C3C=CC56C4(CC(C7(C5CC(CC7)(C)C)CO6)O)C)C)C)O)OC8C(C(C(C(O8)CO)O)O)O)O Ambient -20°C Soluble in DMSO or methanol. "Zhang BZ, Guo XT, Chen JW, et al. Saikosaponin-D Attenuates Heat Stress-Induced Oxidative Damage in LLC-PK1 Cells by Increasing the Expression of Anti-Oxidant Enzymes and HSP72. Am J Chin Med. 2014 Aug 29:1-17. [Epub ahead of print] PMID: 25169909. 

Ying ZL, Li XJ, Dang H, et al. Saikosaponin-d affects the differentiation, maturation and function of monocyte-derived dendritic cells. Exp Ther Med. 2014 May;7(5):1354-1358. PMID: 24940438.

Wong VK, Li T, Law BY, et al. Saikosaponin-d, a novel SERCA inhibitor, induces autophagic cell death in apoptosis-defective cells. Cell Death Dis. 2013 Jul 11;4:e720. PMID: 23846222.

Lu XL, He SX, Ren MD, et al. Chemopreventive effect of saikosaponin-d on diethylinitrosamine-induced hepatocarcinogenesis: involvement of CCAAT/enhancer binding protein β and cyclooxygenase-2. Mol Med Rep. 2012 Mar;5(3):637-44. PMID: 22159471.

Zheng JX, Lu KQ, Xia DG, et al. Therapeutic effects and mechanism of saikosaponin-d in mice with bleomycin-induced pulmonary fibrosis. Zhonghua Yi Xue Za Zhi. 2010 Mar 30;90(12):808-12. PMID: 20450618.

Wang BF, Cheng YA, Dang SS. Angiogenesis inhibitory effect of saikosaponin-d on chicken embryo. Zhongguo Zhong Xi Yi Jie He Za Zhi. 2009 May;29(5):425-9. PMID: 19673334.

Chiang LC, Ng LT, Liu LT, et al. Cytotoxicity and anti-hepatitis B virus activities of saikosaponins from Bupleurum species. Planta Med. 2003 Aug;69(8):705-9. PMID: 14531019.

" Xi Not dangerous goods.

LKT O2146 R-(+)-Ofloxacin 5 mg 658.6 Fluoroquinolone, optically active isomer of ofloxacin; topoisomerase IV and bacterial DNA gyrase inhibitor. (R)-9-Fluoro-2,3-dihydro-3-methyl-10-(4-methyl-1- piperazinyl)-7-oxo-7H-pyrido[1,2,3-de]-1,4-benz- oxazine-6-carboxylic acid 100986-86-5 ≥98% 361.37 C18H20FN3O4 CC1COC2=C3N1C=C(C(=O)C3=CC(=C2N4CCN(CC4)C)F)C(=O)O Ambient Ambient [α]22D (c=0.5, MeOH) +120 "Dwivedi A, Mujtaba SF, Yadav N, et al. Cellular and molecular mechanism of ofloxacin induced apoptotic cell death under ambient UV-A and sunlight exposure. Free Radic Res. 2014 Mar;48(3):333-46. PMID: 24286391.

Pantel A, Petrella S, Matrat S, et al. DNA gyrase inhibition assays are necessary to demonstrate fluoroquinolone resistance secondary to gyrB mutations in Mycobacterium tuberculosis. Antimicrob Agents Chemother. 2011 Oct;55(10):4524-9. PMID: 21768507.

Drlica K, Zhao X. DNA gyrase, topoisomerase IV, and the 4-quinolones. Microbiol Mol Biol Rev. 1997 Sep;61(3):377-92. PMID: 9293187.

" Not dangerous goods.

LKT O2146 R-(+)-Ofloxacin 10 mg 1155.2 Fluoroquinolone, optically active isomer of ofloxacin; topoisomerase IV and bacterial DNA gyrase inhibitor. (R)-9-Fluoro-2,3-dihydro-3-methyl-10-(4-methyl-1- piperazinyl)-7-oxo-7H-pyrido[1,2,3-de]-1,4-benz- oxazine-6-carboxylic acid 100986-86-5 ≥98% 361.37 C18H20FN3O4 CC1COC2=C3N1C=C(C(=O)C3=CC(=C2N4CCN(CC4)C)F)C(=O)O Ambient Ambient [α]22D (c=0.5, MeOH) +120 "Dwivedi A, Mujtaba SF, Yadav N, et al. Cellular and molecular mechanism of ofloxacin induced apoptotic cell death under ambient UV-A and sunlight exposure. Free Radic Res. 2014 Mar;48(3):333-46. PMID: 24286391.

Pantel A, Petrella S, Matrat S, et al. DNA gyrase inhibition assays are necessary to demonstrate fluoroquinolone resistance secondary to gyrB mutations in Mycobacterium tuberculosis. Antimicrob Agents Chemother. 2011 Oct;55(10):4524-9. PMID: 21768507.

Drlica K, Zhao X. DNA gyrase, topoisomerase IV, and the 4-quinolones. Microbiol Mol Biol Rev. 1997 Sep;61(3):377-92. PMID: 9293187.

" Not dangerous goods.

LKT S0133 Saikosaponin C 1 mg 271.7 Triterpene saponin found in Bupleurum. 20736-08-7 ≥98% 927.12 C48H78O17 "CC1C(C(C(C(O1)OC2C(C(C(OC2(C3CCC4(C(C3(C)C)CCC5(C4C=CC67C5(CC(C8(C6CC(CC8)(C)C)CO7)O)C)C)C)OC9C(C(C(C(O9)CO)O)O)O)CO)O)O)O)O)O

" Ambient -20°C Soluble in DMSO. "Shyu KG, Tsai SC, Wang BW, et al. Saikosaponin C induces endothelial cells growth, migration and capillary tube formation. Life Sci. 2004 Dec 31;76(7):813-26. PMID: 15581913.

Chiang LC, Ng LT, Liu LT, et al. Cytotoxicity and anti-hepatitis B virus activities of saikosaponins from Bupleurum species. Planta Med. 2003 Aug;69(8):705-9. PMID: 14531019.

" Xi Not dangerous goods.

LKT S0133 Saikosaponin C 5 mg 570.8 Triterpene saponin found in Bupleurum. 20736-08-7 ≥98% 927.12 C48H78O17 "CC1C(C(C(C(O1)OC2C(C(C(OC2(C3CCC4(C(C3(C)C)CCC5(C4C=CC67C5(CC(C8(C6CC(CC8)(C)C)CO7)O)C)C)C)OC9C(C(C(C(O9)CO)O)O)O)CO)O)O)O)O)O

" Ambient -20°C Soluble in DMSO. "Shyu KG, Tsai SC, Wang BW, et al. Saikosaponin C induces endothelial cells growth, migration and capillary tube formation. Life Sci. 2004 Dec 31;76(7):813-26. PMID: 15581913.

Chiang LC, Ng LT, Liu LT, et al. Cytotoxicity and anti-hepatitis B virus activities of saikosaponins from Bupleurum species. Planta Med. 2003 Aug;69(8):705-9. PMID: 14531019.

" Xi Not dangerous goods.

LKT S0132 Saikosaponin A 1 mg 271.7 Triterpene saponin found in Bupleurum. 20736-09-8 ≥98% 780.98 C42H68O13 CC1C(C(C(C(O1)OC2CCC3(C(C2(C)CO)CCC4(C3C=CC56C4(CC(C7(C5CC(CC7)(C)C)CO6)O)C)C)C)O)OC8C(C(C(C(O8)CO)O)O)O)O Ambient -20°C Soluble in DMSO. "Zhou X, Cheng H, Xu D, et al. Attenuation of Neuropathic Pain by Saikosaponin a in a Rat Model of Chronic Constriction Injury. Neurochem Res. 2014 Aug 9. [Epub ahead of print]. PMID: 25107300.

Yoon SS, Seo JW, Ann SH, et al. Effects of saikosaponin A on cocaine self-administration in rats. Neurosci Lett. 2013 Oct 25;555:198-202. PMID: 24076136.

Kim BM, Hong SH. Sequential caspase-2 and caspase-8 activation is essential for saikosaponin a-induced apoptosis of human colon carcinoma cell lines. Apoptosis. 2011 Feb;16(2):184-97. PMID: 21107704.

Sun Y, Cai TT, Zhou XB, et al. Saikosaponin a inhibits the proliferation and activation of T cells through cell cycle arrest and induction of apoptosis. Int Immunopharmacol. 2009 Jul;9(7-8):978-83. PMID: 19375524.

" Xi Not dangerous goods.

LKT S0132 Saikosaponin A 5 mg 570.8 Triterpene saponin found in Bupleurum. 20736-09-8 ≥98% 780.98 C42H68O13 CC1C(C(C(C(O1)OC2CCC3(C(C2(C)CO)CCC4(C3C=CC56C4(CC(C7(C5CC(CC7)(C)C)CO6)O)C)C)C)O)OC8C(C(C(C(O8)CO)O)O)O)O Ambient -20°C Soluble in DMSO. "Zhou X, Cheng H, Xu D, et al. Attenuation of Neuropathic Pain by Saikosaponin a in a Rat Model of Chronic Constriction Injury. Neurochem Res. 2014 Aug 9. [Epub ahead of print]. PMID: 25107300.

Yoon SS, Seo JW, Ann SH, et al. Effects of saikosaponin A on cocaine self-administration in rats. Neurosci Lett. 2013 Oct 25;555:198-202. PMID: 24076136.

Kim BM, Hong SH. Sequential caspase-2 and caspase-8 activation is essential for saikosaponin a-induced apoptosis of human colon carcinoma cell lines. Apoptosis. 2011 Feb;16(2):184-97. PMID: 21107704.

Sun Y, Cai TT, Zhou XB, et al. Saikosaponin a inhibits the proliferation and activation of T cells through cell cycle arrest and induction of apoptosis. Int Immunopharmacol. 2009 Jul;9(7-8):978-83. PMID: 19375524.

" Xi Not dangerous goods.

LKT O4417 Oleanolic Acid 100 mg 84.3 Triterpenoid found in Vigna angularis and Trigonella foenum-graecum. "Astrantiagenin C; Caryophyllin; Giganteumgenin C; Oleanic acid; Virgaureagenin B 

" 508-02-1 ≥98% 456.71 C30H48O3 CC1(CCC2(CCC3(C(=CCC4C3(CCC5C4(CCC(C5(C)C)O)C)C)C2C1)C)C(=O)O)C Ambient Ambient Soluble in ether, acetone, chloroform or ethanol. Insoluble in water. "Chen JY, Zhang L, Zhang H, et al. Triggering of p38 MAPK and JNK Signaling is Important for Oleanolic Acid-Induced Apoptosis via the Mitochondrial Death Pathway in Hypertrophic Scar Fibroblasts. Phytother Res. 2014 Apr 6. [Epub ahead of print]. PMID: 24706573.

Ghosh S, Bishayee K, Khuda-Bukhsh AR. Oleanolic acid isolated from ethanolic extract of Phytolacca decandra induces apoptosis in A375 skin melanoma cells: drug-DNA interaction and signaling cascade. J Integr Med. 2014 Mar;12(2):102-14.PMID: 24666676.

Kim JY, Cheon YH, Oh HM, et al. Oleanolic acid acetate inhibits osteoclast differentiation by downregulating PLCγ2-Ca(2+)-NFATc1 signaling, and suppresses bone loss in mice. Bone. 2014 Mar;60:104-11. PMID: 24361669.

Kim SH, Hong JH, Lee YC. Oleanolic acid suppresses ovalbumin-induced airway inflammation and Th2-mediated allergic asthma by modulating the transcription factors T-bet, GATA-3, RORγt and Foxp3 in asthmatic mice. Int Immunopharmacol. 2014 Feb;18(2):311-24. PMID: 24374304.

" None Not dangerous goods.

LKT O4417 Oleanolic Acid 500 mg 281.2 Triterpenoid found in Vigna angularis and Trigonella foenum-graecum. "Astrantiagenin C; Caryophyllin; Giganteumgenin C; Oleanic acid; Virgaureagenin B 

" 508-02-1 ≥98% 456.71 C30H48O3 CC1(CCC2(CCC3(C(=CCC4C3(CCC5C4(CCC(C5(C)C)O)C)C)C2C1)C)C(=O)O)C Ambient Ambient Soluble in ether, acetone, chloroform or ethanol. Insoluble in water. "Chen JY, Zhang L, Zhang H, et al. Triggering of p38 MAPK and JNK Signaling is Important for Oleanolic Acid-Induced Apoptosis via the Mitochondrial Death Pathway in Hypertrophic Scar Fibroblasts. Phytother Res. 2014 Apr 6. [Epub ahead of print]. PMID: 24706573.

Ghosh S, Bishayee K, Khuda-Bukhsh AR. Oleanolic acid isolated from ethanolic extract of Phytolacca decandra induces apoptosis in A375 skin melanoma cells: drug-DNA interaction and signaling cascade. J Integr Med. 2014 Mar;12(2):102-14.PMID: 24666676.

Kim JY, Cheon YH, Oh HM, et al. Oleanolic acid acetate inhibits osteoclast differentiation by downregulating PLCγ2-Ca(2+)-NFATc1 signaling, and suppresses bone loss in mice. Bone. 2014 Mar;60:104-11. PMID: 24361669.

Kim SH, Hong JH, Lee YC. Oleanolic acid suppresses ovalbumin-induced airway inflammation and Th2-mediated allergic asthma by modulating the transcription factors T-bet, GATA-3, RORγt and Foxp3 in asthmatic mice. Int Immunopharmacol. 2014 Feb;18(2):311-24. PMID: 24374304.

" None Not dangerous goods.

LKT O4417 Oleanolic Acid 1 g 375.1 Triterpenoid found in Vigna angularis and Trigonella foenum-graecum. "Astrantiagenin C; Caryophyllin; Giganteumgenin C; Oleanic acid; Virgaureagenin B 

" 508-02-1 ≥98% 456.71 C30H48O3 CC1(CCC2(CCC3(C(=CCC4C3(CCC5C4(CCC(C5(C)C)O)C)C)C2C1)C)C(=O)O)C Ambient Ambient Soluble in ether, acetone, chloroform or ethanol. Insoluble in water. "Chen JY, Zhang L, Zhang H, et al. Triggering of p38 MAPK and JNK Signaling is Important for Oleanolic Acid-Induced Apoptosis via the Mitochondrial Death Pathway in Hypertrophic Scar Fibroblasts. Phytother Res. 2014 Apr 6. [Epub ahead of print]. PMID: 24706573.

Ghosh S, Bishayee K, Khuda-Bukhsh AR. Oleanolic acid isolated from ethanolic extract of Phytolacca decandra induces apoptosis in A375 skin melanoma cells: drug-DNA interaction and signaling cascade. J Integr Med. 2014 Mar;12(2):102-14.PMID: 24666676.

Kim JY, Cheon YH, Oh HM, et al. Oleanolic acid acetate inhibits osteoclast differentiation by downregulating PLCγ2-Ca(2+)-NFATc1 signaling, and suppresses bone loss in mice. Bone. 2014 Mar;60:104-11. PMID: 24361669.

Kim SH, Hong JH, Lee YC. Oleanolic acid suppresses ovalbumin-induced airway inflammation and Th2-mediated allergic asthma by modulating the transcription factors T-bet, GATA-3, RORγt and Foxp3 in asthmatic mice. Int Immunopharmacol. 2014 Feb;18(2):311-24. PMID: 24374304.

" None Not dangerous goods.

LKT O4533 Oligomycin 5 mg 97.4 Mixture of oligomycins A, B, C; oxidative phosphorylation inhibitor, potential Na+/K+ ATPase inhibitor. Oligomycin complex 1404-19-9 ≥97% CCC1CCC2C(C(C(C3(O2)CCC(C(O3)CC(C)O)C)C)OC(=O)C=CC(C(C(C(=O)C(C(C(C(=O)C(C(C(CC=CC=C1)C)O)(C)O)C)O)C)C)O)C)C Ambient 4°C Soluble in ethanol, DMSO, acetone. "Liu H, Wang P, Cao M, et al. Protective role of oligomycin against intestinal epithelial barrier dysfunction caused by IFN-γ and TNF-α. Cell Physiol Biochem. 2012;29(5-6):799-808. PMID: 22613980.

Ding Y, Hao J, Rakowski RF. Effects of oligomycin on transient currents carried by Na+ translocation of Bufo Na+/K(+)-ATPase expressed in Xenopus oocytes. J Membr Biol. 2011 Oct;243(1-3):35-46. PMID: 21877177.

Bittar EE. Effect of inhibitors and uncouplers on the Na pump of the Maia muscle fibre. J Physiol. 1966 Nov;187(1):81-103. PMID: 5972170.

CHAPPELL JB, CROFTS AR. THE EFFECT OF ATRACTYLATE AND OLIGOMYCIN ON THE BEHAVIOUR OF MITOCHONDRIA TOWARDS ADENINE NUCLEOTIDES. Biochem J. 1965 Jun;95:707-16. PMID: 14342506.

" Xn Not dangerous goods.

LKT O4533 Oligomycin 10 mg 191.2 Mixture of oligomycins A, B, C; oxidative phosphorylation inhibitor, potential Na+/K+ ATPase inhibitor. Oligomycin complex 1404-19-9 ≥97% CCC1CCC2C(C(C(C3(O2)CCC(C(O3)CC(C)O)C)C)OC(=O)C=CC(C(C(C(=O)C(C(C(C(=O)C(C(C(CC=CC=C1)C)O)(C)O)C)O)C)C)O)C)C Ambient 4°C Soluble in ethanol, DMSO, acetone. "Liu H, Wang P, Cao M, et al. Protective role of oligomycin against intestinal epithelial barrier dysfunction caused by IFN-γ and TNF-α. Cell Physiol Biochem. 2012;29(5-6):799-808. PMID: 22613980.

Ding Y, Hao J, Rakowski RF. Effects of oligomycin on transient currents carried by Na+ translocation of Bufo Na+/K(+)-ATPase expressed in Xenopus oocytes. J Membr Biol. 2011 Oct;243(1-3):35-46. PMID: 21877177.

Bittar EE. Effect of inhibitors and uncouplers on the Na pump of the Maia muscle fibre. J Physiol. 1966 Nov;187(1):81-103. PMID: 5972170.

CHAPPELL JB, CROFTS AR. THE EFFECT OF ATRACTYLATE AND OLIGOMYCIN ON THE BEHAVIOUR OF MITOCHONDRIA TOWARDS ADENINE NUCLEOTIDES. Biochem J. 1965 Jun;95:707-16. PMID: 14342506.

" Xn Not dangerous goods.

LKT O4533 Oligomycin 1 mg 37.5 Mixture of oligomycins A, B, C; oxidative phosphorylation inhibitor, potential Na+/K+ ATPase inhibitor. Oligomycin complex 1404-19-9 ≥97% CCC1CCC2C(C(C(C3(O2)CCC(C(O3)CC(C)O)C)C)OC(=O)C=CC(C(C(C(=O)C(C(C(C(=O)C(C(C(CC=CC=C1)C)O)(C)O)C)O)C)C)O)C)C Ambient 4°C Soluble in ethanol, DMSO, acetone. "Liu H, Wang P, Cao M, et al. Protective role of oligomycin against intestinal epithelial barrier dysfunction caused by IFN-γ and TNF-α. Cell Physiol Biochem. 2012;29(5-6):799-808. PMID: 22613980.

Ding Y, Hao J, Rakowski RF. Effects of oligomycin on transient currents carried by Na+ translocation of Bufo Na+/K(+)-ATPase expressed in Xenopus oocytes. J Membr Biol. 2011 Oct;243(1-3):35-46. PMID: 21877177.

Bittar EE. Effect of inhibitors and uncouplers on the Na pump of the Maia muscle fibre. J Physiol. 1966 Nov;187(1):81-103. PMID: 5972170.

CHAPPELL JB, CROFTS AR. THE EFFECT OF ATRACTYLATE AND OLIGOMYCIN ON THE BEHAVIOUR OF MITOCHONDRIA TOWARDS ADENINE NUCLEOTIDES. Biochem J. 1965 Jun;95:707-16. PMID: 14342506.

" Xn Not dangerous goods.

LKT S0053 α-Santonin 5 g 38.2 Terpene found in Artemesia. [3S-(3α,3aα,5aβ,9bβ)]-3a,5,5a,9b-Tetrahydro-3,5a,9- trimethylnaphthol[1,2-b]furan-2,8(3H,4H)-dione (-)-Santonine; Santonin    481-06-1 ≥98% 246.3 C15H18O3 CC1C2CCC3(C=CC(=O)C(=C3C2OC1=O)C)C Yellows upon exposure to light. Ambient 4°C Soluble in alcohol, ether and chloroform. "Otoguro K, Iwatsuki M, Ishiyama A, et al. In vitro antitrypanosomal activity of plant terpenes against Trypanosoma brucei. Phytochemistry. 2011 Nov;72(16):2024-30. PMID: 21843897.

Arantes FF, Barbosa LC, Alvarenga ES, et al. Synthesis and cytotoxic activity of alpha-santonin derivatives. Eur J Med Chem. 2009 Sep;44(9):3739-45. PMID: 19406535.

Bharathi A, Polasa H. Elimination of ColE1 group (pBR322 and pBR329) plasmids in Escherichia coli by alpha-santonin. FEMS Microbiol Lett. 1990 Mar 1;56(1-2):213-5. PMID: 2185125.

Martín ML, Morán A, Carrón R, et al. Antipyretic activity of alpha- and beta-santonin. J Ethnopharmacol. 1988 Jul-Aug;23(2-3):285-90. PMID: 3193791.

" T+, Xi Not dangerous goods.

LKT S0053 α-Santonin 10 g 55.9 Terpene found in Artemesia. [3S-(3α,3aα,5aβ,9bβ)]-3a,5,5a,9b-Tetrahydro-3,5a,9- trimethylnaphthol[1,2-b]furan-2,8(3H,4H)-dione (-)-Santonine; Santonin    481-06-1 ≥98% 246.3 C15H18O3 CC1C2CCC3(C=CC(=O)C(=C3C2OC1=O)C)C Yellows upon exposure to light. Ambient 4°C Soluble in alcohol, ether and chloroform. "Otoguro K, Iwatsuki M, Ishiyama A, et al. In vitro antitrypanosomal activity of plant terpenes against Trypanosoma brucei. Phytochemistry. 2011 Nov;72(16):2024-30. PMID: 21843897.

Arantes FF, Barbosa LC, Alvarenga ES, et al. Synthesis and cytotoxic activity of alpha-santonin derivatives. Eur J Med Chem. 2009 Sep;44(9):3739-45. PMID: 19406535.

Bharathi A, Polasa H. Elimination of ColE1 group (pBR322 and pBR329) plasmids in Escherichia coli by alpha-santonin. FEMS Microbiol Lett. 1990 Mar 1;56(1-2):213-5. PMID: 2185125.

Martín ML, Morán A, Carrón R, et al. Antipyretic activity of alpha- and beta-santonin. J Ethnopharmacol. 1988 Jul-Aug;23(2-3):285-90. PMID: 3193791.

" T+, Xi Not dangerous goods.

LKT S0053 α-Santonin 25 g 127.1 Terpene found in Artemesia. [3S-(3α,3aα,5aβ,9bβ)]-3a,5,5a,9b-Tetrahydro-3,5a,9- trimethylnaphthol[1,2-b]furan-2,8(3H,4H)-dione (-)-Santonine; Santonin    481-06-1 ≥98% 246.3 C15H18O3 CC1C2CCC3(C=CC(=O)C(=C3C2OC1=O)C)C Yellows upon exposure to light. Ambient 4°C Soluble in alcohol, ether and chloroform. "Otoguro K, Iwatsuki M, Ishiyama A, et al. In vitro antitrypanosomal activity of plant terpenes against Trypanosoma brucei. Phytochemistry. 2011 Nov;72(16):2024-30. PMID: 21843897.

Arantes FF, Barbosa LC, Alvarenga ES, et al. Synthesis and cytotoxic activity of alpha-santonin derivatives. Eur J Med Chem. 2009 Sep;44(9):3739-45. PMID: 19406535.

Bharathi A, Polasa H. Elimination of ColE1 group (pBR322 and pBR329) plasmids in Escherichia coli by alpha-santonin. FEMS Microbiol Lett. 1990 Mar 1;56(1-2):213-5. PMID: 2185125.

Martín ML, Morán A, Carrón R, et al. Antipyretic activity of alpha- and beta-santonin. J Ethnopharmacol. 1988 Jul-Aug;23(2-3):285-90. PMID: 3193791.

" T+, Xi Not dangerous goods.

LKT O4556 Olomoucine 5 mg 181.4 Purine derivative; CDK inhibitor. 6-Benylamino-2-(2-hydroxyethylamino)-9-methyl- purine 2-(Hydroxyethylamino)-6-benzylamino-9-methylpurine 101622-51-9 ≥98% 298.34 C15H18N6O CN1C=NC2=C1N=C(N=C2NCC3=CC=CC=C3)NCCO Ambient -20°C Soluble in DMSO or methanol. "Wandl S, Wesierska-Gadek J. Is olomoucine, a weak CDK2 inhibitor, able to induce apoptosis in cancer cells? Ann N Y Acad Sci. 2009 Aug;1171:242-9. PMID: 19723061.

Fei XF, Qin ZH, Xiang B, et al. Olomoucine inhibits cathepsin L nuclear translocation, activates autophagy and attenuates toxicity of 6-hydroxydopamine. Brain Res. 2009 Apr 6;1264:85-97. PMID: 19368812.

" Not dangerous goods.

LKT O4556 Olomoucine 25 mg 790.7 Purine derivative; CDK inhibitor. 6-Benylamino-2-(2-hydroxyethylamino)-9-methyl- purine 2-(Hydroxyethylamino)-6-benzylamino-9-methylpurine 101622-51-9 ≥98% 298.34 C15H18N6O CN1C=NC2=C1N=C(N=C2NCC3=CC=CC=C3)NCCO Ambient -20°C Soluble in DMSO or methanol. "Wandl S, Wesierska-Gadek J. Is olomoucine, a weak CDK2 inhibitor, able to induce apoptosis in cancer cells? Ann N Y Acad Sci. 2009 Aug;1171:242-9. PMID: 19723061.

Fei XF, Qin ZH, Xiang B, et al. Olomoucine inhibits cathepsin L nuclear translocation, activates autophagy and attenuates toxicity of 6-hydroxydopamine. Brain Res. 2009 Apr 6;1264:85-97. PMID: 19368812.

" Not dangerous goods.

LKT O4556 Olomoucine 100 mg 2157.4 Purine derivative; CDK inhibitor. 6-Benylamino-2-(2-hydroxyethylamino)-9-methyl- purine 2-(Hydroxyethylamino)-6-benzylamino-9-methylpurine 101622-51-9 ≥98% 298.34 C15H18N6O CN1C=NC2=C1N=C(N=C2NCC3=CC=CC=C3)NCCO Ambient -20°C Soluble in DMSO or methanol. "Wandl S, Wesierska-Gadek J. Is olomoucine, a weak CDK2 inhibitor, able to induce apoptosis in cancer cells? Ann N Y Acad Sci. 2009 Aug;1171:242-9. PMID: 19723061.

Fei XF, Qin ZH, Xiang B, et al. Olomoucine inhibits cathepsin L nuclear translocation, activates autophagy and attenuates toxicity of 6-hydroxydopamine. Brain Res. 2009 Apr 6;1264:85-97. PMID: 19368812.

" Not dangerous goods.

LKT O4578 Oltipraz 500 mg 261.1 Antioxidant; Nrf2 activator. 4-Methyl-5-pyrazinyl-3H-1,2-dithiole-3-thione BRN 0978110 64224-21-1 ≥98% 226.34 C8H6N2S3 CC1=C(SSC1=S)C2=NC=CN=C2 Keep away from light. Ambient 4°C Soluble in methanol. "Shimozono R, Asaoka Y, Yoshizawa Y, et al. Nrf2 activators attenuate the progression of nonalcoholic steatohepatitis-related fibrosis in a dietary rat model. Mol Pharmacol. 2013 Jul;84(1):62-70. PMID: 23592516.

Yu Z, Shao W, Chiang Y, et al. Oltipraz upregulates the nuclear factor (erythroid-derived 2)-like 2 [corrected](NRF2) antioxidant system and prevents insulin resistance and obesity induced by a high-fat diet in C57BL/6J mice. Diabetologia. 2011 Apr;54(4):922-34. Erratum in: Diabetologia. 2011 Apr;54(4):989.  PMID: 21161163.

Lee WH, Kim YW, Choi JH, et al. Oltipraz and dithiolethione congeners inhibit hypoxia-inducible factor-1alpha activity through p70 ribosomal S6 kinase-1 inhibition and H2O2-scavenging effect. Mol Cancer Ther. 2009 Oct;8(10):2791-802. PMID: 19789218.

Morsy GH. Parasitological and histo-pathological studies on schistosomiasis mansoni infected mice and treated with praziquatel and/or oltipraz. J Egypt Soc Parasitol. 2009 Aug;39(2):687-701. PMID: 19795775.

Merrell MD, Jackson JP, Augustine LM, et al. The Nrf2 activator oltipraz also activates the constitutive androstane receptor. Drug Metab Dispos. 2008 Aug;36(8):1716-21. PMID: 18474683.

" Xi Not dangerous goods.

LKT O4578 Oltipraz 1 g 412 Antioxidant; Nrf2 activator. 4-Methyl-5-pyrazinyl-3H-1,2-dithiole-3-thione BRN 0978110 64224-21-1 ≥98% 226.34 C8H6N2S3 CC1=C(SSC1=S)C2=NC=CN=C2 Keep away from light. Ambient 4°C Soluble in methanol. "Shimozono R, Asaoka Y, Yoshizawa Y, et al. Nrf2 activators attenuate the progression of nonalcoholic steatohepatitis-related fibrosis in a dietary rat model. Mol Pharmacol. 2013 Jul;84(1):62-70. PMID: 23592516.

Yu Z, Shao W, Chiang Y, et al. Oltipraz upregulates the nuclear factor (erythroid-derived 2)-like 2 [corrected](NRF2) antioxidant system and prevents insulin resistance and obesity induced by a high-fat diet in C57BL/6J mice. Diabetologia. 2011 Apr;54(4):922-34. Erratum in: Diabetologia. 2011 Apr;54(4):989.  PMID: 21161163.

Lee WH, Kim YW, Choi JH, et al. Oltipraz and dithiolethione congeners inhibit hypoxia-inducible factor-1alpha activity through p70 ribosomal S6 kinase-1 inhibition and H2O2-scavenging effect. Mol Cancer Ther. 2009 Oct;8(10):2791-802. PMID: 19789218.

Morsy GH. Parasitological and histo-pathological studies on schistosomiasis mansoni infected mice and treated with praziquatel and/or oltipraz. J Egypt Soc Parasitol. 2009 Aug;39(2):687-701. PMID: 19795775.

Merrell MD, Jackson JP, Augustine LM, et al. The Nrf2 activator oltipraz also activates the constitutive androstane receptor. Drug Metab Dispos. 2008 Aug;36(8):1716-21. PMID: 18474683.

" Xi Not dangerous goods.

LKT S0048 Salicin 5 g 42 Alcoholic β-glucoside found in willow bark, salicylic acid prodrug; serine protease inhibitor. 2-(Hydroxymethyl)phenyl-β-D-glucopyranoside Salicoside; salicyl alcohol glucoside; saligenin-β-D-glucopyranoside 138-52-3 ≥98% 286.28 C13H18O7 C1=CC=C(C(=C1)CO)OC2C(C(C(C(O2)CO)O)O)O Protect from heat and light. Ambient Ambient Soluble in water (43mg/ml) or ethanol (11 mg/ml). "Kong CS, Kim KH, Choi JS, et al. Salicin, an Extract from White Willow Bark, Inhibits Angiogenesis by Blocking the ROS-ERK Pathways. Phytother Res. 2014 Feb 17. [Epub ahead of print]. PMID: 24535656.

Verma N, Verma R, Kumari R, et al. Effect of salicin on gut inflammation and on selected groups of gut microbiota in dextran sodium sulfate induced mouse model of colitis. Inflamm Res. 2014 Feb;63(2):161-9. PMID: 24240229.

Jedinák A, Maliar T, Grancai D, et al. Inhibition activities of natural products on serine proteases. Phytother Res. 2006 Mar;20(3):214-7. PMID: 16521112.

" Xi Not dangerous goods.

LKT S0048 Salicin 25 g 149.5 Alcoholic β-glucoside found in willow bark, salicylic acid prodrug; serine protease inhibitor. 2-(Hydroxymethyl)phenyl-β-D-glucopyranoside Salicoside; salicyl alcohol glucoside; saligenin-β-D-glucopyranoside 138-52-3 ≥98% 286.28 C13H18O7 C1=CC=C(C(=C1)CO)OC2C(C(C(C(O2)CO)O)O)O Protect from heat and light. Ambient Ambient Soluble in water (43mg/ml) or ethanol (11 mg/ml). "Kong CS, Kim KH, Choi JS, et al. Salicin, an Extract from White Willow Bark, Inhibits Angiogenesis by Blocking the ROS-ERK Pathways. Phytother Res. 2014 Feb 17. [Epub ahead of print]. PMID: 24535656.

Verma N, Verma R, Kumari R, et al. Effect of salicin on gut inflammation and on selected groups of gut microbiota in dextran sodium sulfate induced mouse model of colitis. Inflamm Res. 2014 Feb;63(2):161-9. PMID: 24240229.

Jedinák A, Maliar T, Grancai D, et al. Inhibition activities of natural products on serine proteases. Phytother Res. 2006 Mar;20(3):214-7. PMID: 16521112.

" Xi Not dangerous goods.

LKT O4672 Olsalazine Sodium 25 mg 75 5-Aminosalicylate prodrug, NSAID; COX-1/2 inhibitor. 6054-98-4 ≥98% 346.2 C14H8N2Na2O6 C1=CC(=C(C=C1NN=C2C=CC(=O)C(=C2)C(=O)O)C(=O)[O-])[O-].[Na+].[Na+] Ambient Ambient "Malewska K, Rychlik A, Nieradka R, et al. Treatment of inflammatory bowel disease (IBD) in dogs and cats. Pol J Vet Sci. 2011;14(1):165-71. PMID: 21528730.

Rubin DT, LoSavio A, Yadron N, et al. Aminosalicylate therapy in the prevention of dysplasia and colorectal cancer in ulcerative colitis. Clin Gastroenterol Hepatol. 2006 Nov;4(11):1346-50. PMID: 17059900.

Crotty B, Rosenberg WM, Aronson JK, et al. Inhibition of binding of interferon-gamma to its receptor by salicylates used in inflammatory bowel disease. Gut. 1992 Oct;33(10):1353-7. PMID: 1446859.

Kettle AJ, Winterbourn CC. Mechanism of inhibition of myeloperoxidase by anti-inflammatory drugs. Biochem Pharmacol. 1991 May 15;41(10):1485-92. PMID: 1850278.

" Not dangerous goods.

LKT O4672 Olsalazine Sodium 100 mg 187.4 5-Aminosalicylate prodrug, NSAID; COX-1/2 inhibitor. 6054-98-4 ≥98% 346.2 C14H8N2Na2O6 C1=CC(=C(C=C1NN=C2C=CC(=O)C(=C2)C(=O)O)C(=O)[O-])[O-].[Na+].[Na+] Ambient Ambient "Malewska K, Rychlik A, Nieradka R, et al. Treatment of inflammatory bowel disease (IBD) in dogs and cats. Pol J Vet Sci. 2011;14(1):165-71. PMID: 21528730.

Rubin DT, LoSavio A, Yadron N, et al. Aminosalicylate therapy in the prevention of dysplasia and colorectal cancer in ulcerative colitis. Clin Gastroenterol Hepatol. 2006 Nov;4(11):1346-50. PMID: 17059900.

Crotty B, Rosenberg WM, Aronson JK, et al. Inhibition of binding of interferon-gamma to its receptor by salicylates used in inflammatory bowel disease. Gut. 1992 Oct;33(10):1353-7. PMID: 1446859.

Kettle AJ, Winterbourn CC. Mechanism of inhibition of myeloperoxidase by anti-inflammatory drugs. Biochem Pharmacol. 1991 May 15;41(10):1485-92. PMID: 1850278.

" Not dangerous goods.

LKT O4672 Olsalazine Sodium 250 mg 375.1 5-Aminosalicylate prodrug, NSAID; COX-1/2 inhibitor. 6054-98-4 ≥98% 346.2 C14H8N2Na2O6 C1=CC(=C(C=C1NN=C2C=CC(=O)C(=C2)C(=O)O)C(=O)[O-])[O-].[Na+].[Na+] Ambient Ambient "Malewska K, Rychlik A, Nieradka R, et al. Treatment of inflammatory bowel disease (IBD) in dogs and cats. Pol J Vet Sci. 2011;14(1):165-71. PMID: 21528730.

Rubin DT, LoSavio A, Yadron N, et al. Aminosalicylate therapy in the prevention of dysplasia and colorectal cancer in ulcerative colitis. Clin Gastroenterol Hepatol. 2006 Nov;4(11):1346-50. PMID: 17059900.

Crotty B, Rosenberg WM, Aronson JK, et al. Inhibition of binding of interferon-gamma to its receptor by salicylates used in inflammatory bowel disease. Gut. 1992 Oct;33(10):1353-7. PMID: 1446859.

Kettle AJ, Winterbourn CC. Mechanism of inhibition of myeloperoxidase by anti-inflammatory drugs. Biochem Pharmacol. 1991 May 15;41(10):1485-92. PMID: 1850278.

" Not dangerous goods.

LKT O4917 Omeprazole 1 g 115.5 H+/K+ ATPase inhibitor. 5-Methoxy-2-[[(4-methoxy-3,5-dimethyl-2-pyridinyl)methyl]sulfinyl]-1H-benzimidazole Antra; Gastrogard; Losec; Mepral; Omepral; Parizac' Prilosec; Zoltum 73590-58-6 ≥98% 345.42 C17H19N3O3S CC1=CN=C(C(=C1OC)C)CS(=O)C2=NC3=C(N2)C=C(C=C3)OC Ambient 4°C Soluble in ethanol or methanol. Slightly soluble in acetone, isopropanol, or water. "Tonazzi A, Eberini I, Indiveri C. Molecular mechanism of inhibition of the mitochondrial carnitine/acylcarnitine transporter by omeprazole revealed by proteoliposome assay, mutagenesis and bioinformatics. PLoS One. 2013 Dec 9;8(12):e82286. PMID: 24349247.

Ward RM, Kearns GL. Proton pump inhibitors in pediatrics : mechanism of action, pharmacokinetics, pharmacogenetics, and pharmacodynamics. Paediatr Drugs. 2013 Apr;15(2):119-31. PMID: 23512128.

Mefford IN, Mefford JT, Burris CA. Improved diabetes control and pancreatic function in a type 2 diabetic after omeprazole administration. Case Rep Endocrinol. 2012;2012:468609. PMID: 22937295.

" Xi Not dangerous goods.

LKT O4917 Omeprazole 5 g 407.7 H+/K+ ATPase inhibitor. 5-Methoxy-2-[[(4-methoxy-3,5-dimethyl-2-pyridinyl)methyl]sulfinyl]-1H-benzimidazole Antra; Gastrogard; Losec; Mepral; Omepral; Parizac' Prilosec; Zoltum 73590-58-6 ≥98% 345.42 C17H19N3O3S CC1=CN=C(C(=C1OC)C)CS(=O)C2=NC3=C(N2)C=C(C=C3)OC Ambient 4°C Soluble in ethanol or methanol. Slightly soluble in acetone, isopropanol, or water. "Tonazzi A, Eberini I, Indiveri C. Molecular mechanism of inhibition of the mitochondrial carnitine/acylcarnitine transporter by omeprazole revealed by proteoliposome assay, mutagenesis and bioinformatics. PLoS One. 2013 Dec 9;8(12):e82286. PMID: 24349247.

Ward RM, Kearns GL. Proton pump inhibitors in pediatrics : mechanism of action, pharmacokinetics, pharmacogenetics, and pharmacodynamics. Paediatr Drugs. 2013 Apr;15(2):119-31. PMID: 23512128.

Mefford IN, Mefford JT, Burris CA. Improved diabetes control and pancreatic function in a type 2 diabetic after omeprazole administration. Case Rep Endocrinol. 2012;2012:468609. PMID: 22937295.

" Xi Not dangerous goods.

LKT O4917 Omeprazole 10 g 475.7 H+/K+ ATPase inhibitor. 5-Methoxy-2-[[(4-methoxy-3,5-dimethyl-2-pyridinyl)methyl]sulfinyl]-1H-benzimidazole Antra; Gastrogard; Losec; Mepral; Omepral; Parizac' Prilosec; Zoltum 73590-58-6 ≥98% 345.42 C17H19N3O3S CC1=CN=C(C(=C1OC)C)CS(=O)C2=NC3=C(N2)C=C(C=C3)OC Ambient 4°C Soluble in ethanol or methanol. Slightly soluble in acetone, isopropanol, or water. "Tonazzi A, Eberini I, Indiveri C. Molecular mechanism of inhibition of the mitochondrial carnitine/acylcarnitine transporter by omeprazole revealed by proteoliposome assay, mutagenesis and bioinformatics. PLoS One. 2013 Dec 9;8(12):e82286. PMID: 24349247.

Ward RM, Kearns GL. Proton pump inhibitors in pediatrics : mechanism of action, pharmacokinetics, pharmacogenetics, and pharmacodynamics. Paediatr Drugs. 2013 Apr;15(2):119-31. PMID: 23512128.

Mefford IN, Mefford JT, Burris CA. Improved diabetes control and pancreatic function in a type 2 diabetic after omeprazole administration. Case Rep Endocrinol. 2012;2012:468609. PMID: 22937295.

" Xi Not dangerous goods.

LKT O5212 Ondansetron Hydrochloride Dihydrate 100 mg 130 5-HT3 antagonist. 1,2,3,9-Tetrahydro-9-methyl-3-[(2-methyl-1H- imidazol-1-yl)methyl]-4H-carbazol-4-one hydrochloride dihydrate Zofran; Zophren 99614-01-4 ≥98% 365.86 C18H19N3O HCl 2H2O CC1=NC=CN1CC2CCC3=C(C2=O)C4=CC=CC=C4N3C.Cl Ambient -20°C Soluble in water. "Kurhe Y, Radhakrishnan M, Gupta D. Ondansetron attenuates depression co-morbid with obesity in obese mice subjected to chronic unpredictable mild stress; an approach using behavioral battery tests. Metab Brain Dis. 2014 Jun 27. [Epub ahead of print]. PMID: 24964970.

Rojas C, Raje M, Tsukamoto T, et al. Molecular mechanisms of 5-HT(3) and NK(1) receptor antagonists in prevention of emesis. Eur J Pharmacol. 2014 Jan 5;722:26-37. PMID: 24184669.

" T "UN number: 2811     Class: 6.1     Packing Group: III

Proper shipping name: Toxic solid, organic, n.o.s. (Ondansetron)"

LKT O5212 Ondansetron Hydrochloride Dihydrate 500 mg 545.1 5-HT3 antagonist. 1,2,3,9-Tetrahydro-9-methyl-3-[(2-methyl-1H- imidazol-1-yl)methyl]-4H-carbazol-4-one hydrochloride dihydrate Zofran; Zophren 99614-01-4 ≥98% 365.86 C18H19N3O HCl 2H2O CC1=NC=CN1CC2CCC3=C(C2=O)C4=CC=CC=C4N3C.Cl Ambient -20°C Soluble in water. "Kurhe Y, Radhakrishnan M, Gupta D. Ondansetron attenuates depression co-morbid with obesity in obese mice subjected to chronic unpredictable mild stress; an approach using behavioral battery tests. Metab Brain Dis. 2014 Jun 27. [Epub ahead of print]. PMID: 24964970.

Rojas C, Raje M, Tsukamoto T, et al. Molecular mechanisms of 5-HT(3) and NK(1) receptor antagonists in prevention of emesis. Eur J Pharmacol. 2014 Jan 5;722:26-37. PMID: 24184669.

" T "UN number: 2811     Class: 6.1     Packing Group: III

Proper shipping name: Toxic solid, organic, n.o.s. (Ondansetron)"

LKT O6132 Opioid Receptor Antagonist Ac-RFMWMK-NH2 1 mg 201.8 Peptide; μ/δ/κ-OR inhibitor. ≥98% 939.2 C44H66N12O7S2 Ambient -20°C Dooley CT, Chung NN, Schiller PW, et al. Acetalins: opioid receptor antagonists determined through the use of synthetic peptide combinatorial libraries. Proc Natl Acad Sci U S A. 1993 Nov 15;90(22):10811-5. PMID: 8248174. Not dangerous goods.

LKT O6845 Orlistat  100 mg 94.4 Fatty acid synthase inhibitor. N-Formyl-L-leucine(1S)-1-[[(2S,3S)-3-hexyl-4-oxo-2-oxetanyl]methyl]-dodecyl ester Orlipastat; Xenical 96829-58-2 ≥98% 495.73 C29H53NO5 "CCCCCCCCCCCC(CC1C(C(=O)O1)CCCCCC)OC(=O)C(CC(C)C)NC=O

" Protect from light and moisture. Ambient 4°C Soluble in DMSO or ethanol. "Kant S, Kumar A, Singh SM. Tumor growth retardation and chemosensitizing action of fatty acid synthase inhibitor orlistat on T cell lymphoma: implication of reconstituted tumor microenvironment and multidrug resistance phenotype. Biochim Biophys Acta. 2014 Jan;1840(1):294-302. PMID: 24060750.

Chuang HY, Chang YF, Hwang JJ. Antitumor effect of orlistat, a fatty acid synthase inhibitor, is via activation of caspase-3 on human colorectal carcinoma-bearing animal. Biomed Pharmacother. 2011 Jul;65(4):286-92. PMID: 21723078.

Halpern A, Pepe RB, Monegaglia AP, et al. Efficacy and tolerability of the association of sibutramine and orlistat for six months in overweight and obese patients. J Obes. 2010;2010. pii: 602537. PMID: 20871858.

" Not dangerous.

LKT O6845 Orlistat  500 mg 252.1 Fatty acid synthase inhibitor. N-Formyl-L-leucine(1S)-1-[[(2S,3S)-3-hexyl-4-oxo-2-oxetanyl]methyl]-dodecyl ester Orlipastat; Xenical 96829-58-2 ≥98% 495.73 C29H53NO5 "CCCCCCCCCCCC(CC1C(C(=O)O1)CCCCCC)OC(=O)C(CC(C)C)NC=O

" Protect from light and moisture. Ambient 4°C Soluble in DMSO or ethanol. "Kant S, Kumar A, Singh SM. Tumor growth retardation and chemosensitizing action of fatty acid synthase inhibitor orlistat on T cell lymphoma: implication of reconstituted tumor microenvironment and multidrug resistance phenotype. Biochim Biophys Acta. 2014 Jan;1840(1):294-302. PMID: 24060750.

Chuang HY, Chang YF, Hwang JJ. Antitumor effect of orlistat, a fatty acid synthase inhibitor, is via activation of caspase-3 on human colorectal carcinoma-bearing animal. Biomed Pharmacother. 2011 Jul;65(4):286-92. PMID: 21723078.

Halpern A, Pepe RB, Monegaglia AP, et al. Efficacy and tolerability of the association of sibutramine and orlistat for six months in overweight and obese patients. J Obes. 2010;2010. pii: 602537. PMID: 20871858.

" Not dangerous.

LKT O6845 Orlistat  1 g 420.1 Fatty acid synthase inhibitor. N-Formyl-L-leucine(1S)-1-[[(2S,3S)-3-hexyl-4-oxo-2-oxetanyl]methyl]-dodecyl ester Orlipastat; Xenical 96829-58-2 ≥98% 495.73 C29H53NO5 "CCCCCCCCCCCC(CC1C(C(=O)O1)CCCCCC)OC(=O)C(CC(C)C)NC=O

" Protect from light and moisture. Ambient 4°C Soluble in DMSO or ethanol. "Kant S, Kumar A, Singh SM. Tumor growth retardation and chemosensitizing action of fatty acid synthase inhibitor orlistat on T cell lymphoma: implication of reconstituted tumor microenvironment and multidrug resistance phenotype. Biochim Biophys Acta. 2014 Jan;1840(1):294-302. PMID: 24060750.

Chuang HY, Chang YF, Hwang JJ. Antitumor effect of orlistat, a fatty acid synthase inhibitor, is via activation of caspase-3 on human colorectal carcinoma-bearing animal. Biomed Pharmacother. 2011 Jul;65(4):286-92. PMID: 21723078.

Halpern A, Pepe RB, Monegaglia AP, et al. Efficacy and tolerability of the association of sibutramine and orlistat for six months in overweight and obese patients. J Obes. 2010;2010. pii: 602537. PMID: 20871858.

" Not dangerous.

LKT S0046 Salsolidine 25 mg 69.3 Tetrahydroisoquinolone alkaloid found in Salsola; MAO, AChE, BChE inhibitor, potential COMT inhibitor. Isoquinoline,1,2,3,4-tetrahydro-6,7-dimethoxy-1-methyl (S)-(-)-Salsolidine; (S)-Salsolidine; (-)-Salsolidine 493-48-1 ≥98% 207.27 C12H17NO2 CC1C2=CC(=C(C=C2CCN1)OC)OC Protect from light. Ambient 4°C "Talhout R, Opperhuizen A, van Amsterdam JG. Role of acetaldehyde in tobacco smoke addiction. Eur Neuropsychopharmacol. 2007 Oct;17(10):627-36. PMID: 17382522.

Bembenek ME, Abell CW, Chrisey LA, et al. Inhibition of monoamine oxidases A and B by simple isoquinoline alkaloids: racemic and optically active 1,2,3,4-tetrahydro-, 3,4-dihydro-, and fully aromatic isoquinolines. J Med Chem. 1990 Jan;33(1):147-52. PMID: 2296014.

" Not dangerous goods.

LKT S0046 Salsolidine 100 mg 196.8 Tetrahydroisoquinolone alkaloid found in Salsola; MAO, AChE, BChE inhibitor, potential COMT inhibitor. Isoquinoline,1,2,3,4-tetrahydro-6,7-dimethoxy-1-methyl (S)-(-)-Salsolidine; (S)-Salsolidine; (-)-Salsolidine 493-48-1 ≥98% 207.27 C12H17NO2 CC1C2=CC(=C(C=C2CCN1)OC)OC Protect from light. Ambient 4°C "Talhout R, Opperhuizen A, van Amsterdam JG. Role of acetaldehyde in tobacco smoke addiction. Eur Neuropsychopharmacol. 2007 Oct;17(10):627-36. PMID: 17382522.

Bembenek ME, Abell CW, Chrisey LA, et al. Inhibition of monoamine oxidases A and B by simple isoquinoline alkaloids: racemic and optically active 1,2,3,4-tetrahydro-, 3,4-dihydro-, and fully aromatic isoquinolines. J Med Chem. 1990 Jan;33(1):147-52. PMID: 2296014.

" Not dangerous goods.

LKT S0045 Salbutamol Sulfate 25 mg 55 β2-adrenergic agonist. α1-[[(1,1-Dimethylethyl)amino]methyl]-4-hydroxy- 1,3-benzenedimethanol sulfate Aerolin; Asmaven; Ecovent; Loftan; Salbumol; Salbuvent; Venetlin; Volmax; salbutamol hemisulfate 51022-70-9 ≥98% 576.7 (C13H21NO3)2 H2SO4 CC(C)(C)NCC(C1=CC(=C(C=C1)O)CO)O.CC(C)(C)NCC(C1=CC(=C(C=C1)O)CO)O.OS(=O)(=O)O Light sensitive. Ambient Ambient Soluble in water. Slightly soluble in ethanol. "Matsumoto K, Aizawa H, Fukuyama S, et al. Low-dose salbutamol suppresses airway responsiveness to histamine but not methacholine in subjects with asthma. Respir Investig. 2013 Sep;51(3):158-65. PMID: 23978642.

Uzkeser H, Cadirci E, Halici Z, et al. Anti-inflammatory and antinociceptive effects of salbutamol on acute and chronic models of inflammation in rats: involvement of an antioxidant mechanism. Mediators Inflamm. 2012;2012:438912. PMID: 22665951.

" None Not dangerous goods.

LKT S0045 Salbutamol Sulfate 50 mg 96.2 β2-adrenergic agonist. α1-[[(1,1-Dimethylethyl)amino]methyl]-4-hydroxy- 1,3-benzenedimethanol sulfate Aerolin; Asmaven; Ecovent; Loftan; Salbumol; Salbuvent; Venetlin; Volmax; salbutamol hemisulfate 51022-70-9 ≥98% 576.7 (C13H21NO3)2 H2SO4 CC(C)(C)NCC(C1=CC(=C(C=C1)O)CO)O.CC(C)(C)NCC(C1=CC(=C(C=C1)O)CO)O.OS(=O)(=O)O Light sensitive. Ambient Ambient Soluble in water. Slightly soluble in ethanol. "Matsumoto K, Aizawa H, Fukuyama S, et al. Low-dose salbutamol suppresses airway responsiveness to histamine but not methacholine in subjects with asthma. Respir Investig. 2013 Sep;51(3):158-65. PMID: 23978642.

Uzkeser H, Cadirci E, Halici Z, et al. Anti-inflammatory and antinociceptive effects of salbutamol on acute and chronic models of inflammation in rats: involvement of an antioxidant mechanism. Mediators Inflamm. 2012;2012:438912. PMID: 22665951.

" None Not dangerous goods.

LKT S0045 Salbutamol Sulfate 100 mg 159.3 β2-adrenergic agonist. α1-[[(1,1-Dimethylethyl)amino]methyl]-4-hydroxy- 1,3-benzenedimethanol sulfate Aerolin; Asmaven; Ecovent; Loftan; Salbumol; Salbuvent; Venetlin; Volmax; salbutamol hemisulfate 51022-70-9 ≥98% 576.7 (C13H21NO3)2 H2SO4 CC(C)(C)NCC(C1=CC(=C(C=C1)O)CO)O.CC(C)(C)NCC(C1=CC(=C(C=C1)O)CO)O.OS(=O)(=O)O Light sensitive. Ambient Ambient Soluble in water. Slightly soluble in ethanol. "Matsumoto K, Aizawa H, Fukuyama S, et al. Low-dose salbutamol suppresses airway responsiveness to histamine but not methacholine in subjects with asthma. Respir Investig. 2013 Sep;51(3):158-65. PMID: 23978642.

Uzkeser H, Cadirci E, Halici Z, et al. Anti-inflammatory and antinociceptive effects of salbutamol on acute and chronic models of inflammation in rats: involvement of an antioxidant mechanism. Mediators Inflamm. 2012;2012:438912. PMID: 22665951.

" None Not dangerous goods.

LKT S0045 Salbutamol Sulfate 500 mg 576.6 β2-adrenergic agonist. α1-[[(1,1-Dimethylethyl)amino]methyl]-4-hydroxy- 1,3-benzenedimethanol sulfate Aerolin; Asmaven; Ecovent; Loftan; Salbumol; Salbuvent; Venetlin; Volmax; salbutamol hemisulfate 51022-70-9 ≥98% 576.7 (C13H21NO3)2 H2SO4 CC(C)(C)NCC(C1=CC(=C(C=C1)O)CO)O.CC(C)(C)NCC(C1=CC(=C(C=C1)O)CO)O.OS(=O)(=O)O Light sensitive. Ambient Ambient Soluble in water. Slightly soluble in ethanol. "Matsumoto K, Aizawa H, Fukuyama S, et al. Low-dose salbutamol suppresses airway responsiveness to histamine but not methacholine in subjects with asthma. Respir Investig. 2013 Sep;51(3):158-65. PMID: 23978642.

Uzkeser H, Cadirci E, Halici Z, et al. Anti-inflammatory and antinociceptive effects of salbutamol on acute and chronic models of inflammation in rats: involvement of an antioxidant mechanism. Mediators Inflamm. 2012;2012:438912. PMID: 22665951.

" None Not dangerous goods.

LKT S0044 Salbutamol Free Base 25 mg 55 β2-adrenergic agonist. α1-[[(1,1-Dimethylethyl)amino]methyl]-4-hydroxy- 1,3-benzenedimethanol Albuterol; Salbutamol 18559-94-9 ≥98% 239.31 C13H21NO3 CC(C)(C)NCC(C1=CC(=C(C=C1)O)CO)O Ambient Ambient Soluble in most organic solvents. "Matsumoto K, Aizawa H, Fukuyama S, et al. Low-dose salbutamol suppresses airway responsiveness to histamine but not methacholine in subjects with asthma. Respir Investig. 2013 Sep;51(3):158-65. PMID: 23978642.

Uzkeser H, Cadirci E, Halici Z, et al. Anti-inflammatory and antinociceptive effects of salbutamol on acute and chronic models of inflammation in rats: involvement of an antioxidant mechanism. Mediators Inflamm. 2012;2012:438912. PMID: 22665951.

" Xn Not dangerous goods.

LKT S0044 Salbutamol Free Base 50 mg 96.2 β2-adrenergic agonist. α1-[[(1,1-Dimethylethyl)amino]methyl]-4-hydroxy- 1,3-benzenedimethanol Albuterol; Salbutamol 18559-94-9 ≥98% 239.31 C13H21NO3 CC(C)(C)NCC(C1=CC(=C(C=C1)O)CO)O Ambient Ambient Soluble in most organic solvents. "Matsumoto K, Aizawa H, Fukuyama S, et al. Low-dose salbutamol suppresses airway responsiveness to histamine but not methacholine in subjects with asthma. Respir Investig. 2013 Sep;51(3):158-65. PMID: 23978642.

Uzkeser H, Cadirci E, Halici Z, et al. Anti-inflammatory and antinociceptive effects of salbutamol on acute and chronic models of inflammation in rats: involvement of an antioxidant mechanism. Mediators Inflamm. 2012;2012:438912. PMID: 22665951.

" Xn Not dangerous goods.

LKT O6953 Ornidazole 5 g 58.8 5-Nitroimidazole derivative; genotoxic. Tiberal, Madelen 16773-42-5 ≥98% 219.63 C7H10ClN3O3 CC1=NC=C(N1CC(CCl)O)[N+](=O)[O-] Ambient Ambient "Thulkar J, Kriplani A, Agarwal N. A comparative study of oral single dose of metronidazole, tinidazole, secnidazole and ornidazole in bacterial vaginosis. Indian J Pharmacol. 2012 Mar;44(2):243-5. PMID: 22529484.

Ikbal M, Yilmaz G, Dogan H, et al. The evaluation of genotoxic potential of ornidazole, nitroimidazole, in lymphocyte culture of patients with amebiasis. Drug Chem Toxicol. 2011 Apr;34(2):162-6. PMID: 21314465.

Raether W, Hänel H. Nitroheterocyclic drugs with broad spectrum activity. Parasitol Res. 2003 Jun;90 Supp 1:S19-39. PMID: 12811546.

" Xn Not dangerous goods.

LKT S0044 Salbutamol Free Base 100 mg 164.7 β2-adrenergic agonist. α1-[[(1,1-Dimethylethyl)amino]methyl]-4-hydroxy- 1,3-benzenedimethanol Albuterol; Salbutamol 18559-94-9 ≥98% 239.31 C13H21NO3 CC(C)(C)NCC(C1=CC(=C(C=C1)O)CO)O Ambient Ambient Soluble in most organic solvents. "Matsumoto K, Aizawa H, Fukuyama S, et al. Low-dose salbutamol suppresses airway responsiveness to histamine but not methacholine in subjects with asthma. Respir Investig. 2013 Sep;51(3):158-65. PMID: 23978642.

Uzkeser H, Cadirci E, Halici Z, et al. Anti-inflammatory and antinociceptive effects of salbutamol on acute and chronic models of inflammation in rats: involvement of an antioxidant mechanism. Mediators Inflamm. 2012;2012:438912. PMID: 22665951.

" Xn Not dangerous goods.

LKT O6953 Ornidazole 50 g 456.8 5-Nitroimidazole derivative; genotoxic. Tiberal, Madelen 16773-42-5 ≥98% 219.63 C7H10ClN3O3 CC1=NC=C(N1CC(CCl)O)[N+](=O)[O-] Ambient Ambient "Thulkar J, Kriplani A, Agarwal N. A comparative study of oral single dose of metronidazole, tinidazole, secnidazole and ornidazole in bacterial vaginosis. Indian J Pharmacol. 2012 Mar;44(2):243-5. PMID: 22529484.

Ikbal M, Yilmaz G, Dogan H, et al. The evaluation of genotoxic potential of ornidazole, nitroimidazole, in lymphocyte culture of patients with amebiasis. Drug Chem Toxicol. 2011 Apr;34(2):162-6. PMID: 21314465.

Raether W, Hänel H. Nitroheterocyclic drugs with broad spectrum activity. Parasitol Res. 2003 Jun;90 Supp 1:S19-39. PMID: 12811546.

" Xn Not dangerous goods.

LKT S0044 Salbutamol Free Base 500 mg 603.8 β2-adrenergic agonist. α1-[[(1,1-Dimethylethyl)amino]methyl]-4-hydroxy- 1,3-benzenedimethanol Albuterol; Salbutamol 18559-94-9 ≥98% 239.31 C13H21NO3 CC(C)(C)NCC(C1=CC(=C(C=C1)O)CO)O Ambient Ambient Soluble in most organic solvents. "Matsumoto K, Aizawa H, Fukuyama S, et al. Low-dose salbutamol suppresses airway responsiveness to histamine but not methacholine in subjects with asthma. Respir Investig. 2013 Sep;51(3):158-65. PMID: 23978642.

Uzkeser H, Cadirci E, Halici Z, et al. Anti-inflammatory and antinociceptive effects of salbutamol on acute and chronic models of inflammation in rats: involvement of an antioxidant mechanism. Mediators Inflamm. 2012;2012:438912. PMID: 22665951.

" Xn Not dangerous goods.

LKT O7053 L-Ornithine Hydrochloride 10 g 27.8 Non-proteinogenic amino acid, L-arginine metabolite, involved in the urea cycle. L-Ornithine Monohydrochloride 2,5-Diaminopentanoic acid Monohydrochloride 3184-13-2 ≥98% 168.62 C5H12N2O2 HCl C(CC(C(=O)O)N)CN.Cl Ambient Ambient Soluble in water and alcohol. "Ivanenkov YA, Chufarova NV. Small-molecule arginase inhibitors. Pharm Pat Anal. 2014 Jan;3(1):65-85. PMID: 24354980.

Sikorska H, Cianciara J, Wiercińska-Drapało A. Physiological functions of L-ornithine and L-aspartate in the body and the efficacy of administration of L-ornithine-L-aspartate in conditions of relative deficiency. Pol Merkur Lekarski. 2010 Jun;28(168):490-5. PMID: 20642112.

Sugino T, Shirai T, Kajimoto Y, et al. L-ornithine supplementation attenuates physical fatigue in healthy volunteers by modulating lipid and amino acid metabolism. Nutr Res. 2008 Nov;28(11):738-43. PMID: 19083482.

" Not dangerous goods.

LKT O7053 L-Ornithine Hydrochloride 25 g 37.3 Non-proteinogenic amino acid, L-arginine metabolite, involved in the urea cycle. L-Ornithine Monohydrochloride 2,5-Diaminopentanoic acid Monohydrochloride 3184-13-2 ≥98% 168.62 C5H12N2O2 HCl C(CC(C(=O)O)N)CN.Cl Ambient Ambient Soluble in water and alcohol. "Ivanenkov YA, Chufarova NV. Small-molecule arginase inhibitors. Pharm Pat Anal. 2014 Jan;3(1):65-85. PMID: 24354980.

Sikorska H, Cianciara J, Wiercińska-Drapało A. Physiological functions of L-ornithine and L-aspartate in the body and the efficacy of administration of L-ornithine-L-aspartate in conditions of relative deficiency. Pol Merkur Lekarski. 2010 Jun;28(168):490-5. PMID: 20642112.

Sugino T, Shirai T, Kajimoto Y, et al. L-ornithine supplementation attenuates physical fatigue in healthy volunteers by modulating lipid and amino acid metabolism. Nutr Res. 2008 Nov;28(11):738-43. PMID: 19083482.

" Not dangerous goods.

LKT O7053 L-Ornithine Hydrochloride 100 g 88 Non-proteinogenic amino acid, L-arginine metabolite, involved in the urea cycle. L-Ornithine Monohydrochloride 2,5-Diaminopentanoic acid Monohydrochloride 3184-13-2 ≥98% 168.62 C5H12N2O2 HCl C(CC(C(=O)O)N)CN.Cl Ambient Ambient Soluble in water and alcohol. "Ivanenkov YA, Chufarova NV. Small-molecule arginase inhibitors. Pharm Pat Anal. 2014 Jan;3(1):65-85. PMID: 24354980.

Sikorska H, Cianciara J, Wiercińska-Drapało A. Physiological functions of L-ornithine and L-aspartate in the body and the efficacy of administration of L-ornithine-L-aspartate in conditions of relative deficiency. Pol Merkur Lekarski. 2010 Jun;28(168):490-5. PMID: 20642112.

Sugino T, Shirai T, Kajimoto Y, et al. L-ornithine supplementation attenuates physical fatigue in healthy volunteers by modulating lipid and amino acid metabolism. Nutr Res. 2008 Nov;28(11):738-43. PMID: 19083482.

" Not dangerous goods.

LKT O7053 L-Ornithine Hydrochloride 1 kg 543.1 Non-proteinogenic amino acid, L-arginine metabolite, involved in the urea cycle. L-Ornithine Monohydrochloride 2,5-Diaminopentanoic acid Monohydrochloride 3184-13-2 ≥98% 168.62 C5H12N2O2 HCl C(CC(C(=O)O)N)CN.Cl Ambient Ambient Soluble in water and alcohol. "Ivanenkov YA, Chufarova NV. Small-molecule arginase inhibitors. Pharm Pat Anal. 2014 Jan;3(1):65-85. PMID: 24354980.

Sikorska H, Cianciara J, Wiercińska-Drapało A. Physiological functions of L-ornithine and L-aspartate in the body and the efficacy of administration of L-ornithine-L-aspartate in conditions of relative deficiency. Pol Merkur Lekarski. 2010 Jun;28(168):490-5. PMID: 20642112.

Sugino T, Shirai T, Kajimoto Y, et al. L-ornithine supplementation attenuates physical fatigue in healthy volunteers by modulating lipid and amino acid metabolism. Nutr Res. 2008 Nov;28(11):738-43. PMID: 19083482.

" Not dangerous goods.

LKT O7116 Orexin B, human 1 mg 447.4 Endogenous peptide neurotransmitter, involved in circadian rhythms and feeding behaviors; OX2 agonist. Hypocretin-2 ≥95% 2899.4 C123H212N44O35S CCC(C)C(C(=O)NCC(=O)NC(C)C(=O)NC(C)C(=O)NC(CC1=CNC=N1)C(=O)NC(CC(=O)N)C(=O)NCC(=O)NC(CO)C(=O)NC(C)C(=O)NC(CCC(=O)N)C(=O)NC(CC(C)C)C(=O)NC(CC(C)C)C(=O)NC(CCCN=C(N)N)C(=O)NC(CCC(=O)N)C(=O)NC(CC(C)C)C(=O)NC(CCCN=C(N)N)C(=O)NCC(=O)NC(CCC(=O)N)C(=O)NC(CC(C)C)C(=O)NCC(=O)N2CCCC2C(=O)N3CCCC3C(=O)NCC(=O)NC(CO)C(=O)NC(CCCN=C(N)N)C(=O)N)NC(=O)C(CC(C)C)NC(=O)C(C(C)O)NC(=O)C(CCSC)N Ambient -20°C "Cataldi NI, Lux Lantos VA, Libertun C. Orexin A and B in vitro modify orexins receptors expression and gonadotropins secretion of anterior pituitary cells of proestrous rats. Regul Pept. 2014 Jan 10;188:25-30. PMID: 24333629.

Sokołowska P, Urbańska A, Biegańska K, et al. Orexins protect neuronal cell cultures against hypoxic stress: an involvement of Akt signaling. J Mol Neurosci. 2014 Jan;52(1):48-55. PMID: 24243084.

Tsuji T, Yamamoto T, Tanaka S, et al. Analyses of the facilitatory effect of orexin on eating and masticatory muscle activity in rats. J Neurophysiol. 2011 Dec;106(6):3129-35. PMID: 21940607.

Adeghate E, Hameed R. Mechanism of orexin B-stimulated insulin and glucagon release from the pancreas of normal and diabetic rats. Pancreas. 2011 Jan;40(1):131-6. PMID: 20871474.

Di Sebastiano AR, Yong-Yow S, Wagner L, et al. Orexin mediates initiation of sexual behavior in sexually naive male rats, but is not critical for sexual performance. Horm Behav. 2010 Aug;58(3):397-404. PMID: 20541554.

" Not dangerous goods.

LKT O7218 Oseltamivir Phosphate 10 mg 93.8 Viral neuraminidase inhibitor, potential MAO-A inhibitor. 204255-11-8 ≥98% 410.4 C16H28N2O4 H3O4P CCC(CC)OC1C=C(CC(C1NC(=O)C)N)C(=O)OCC.OP(=O)(O)O Ambient 4°C "Huang L, Cao Y, Zhou J, et al. A conformational restriction in influenza A virus neuraminidase binding site by R152 caused the combinational effect of I222T with H274Y on oseltamivir resistance. Antimicrob Agents Chemother. 2013 Dec 23. [Epub ahead of print]. PMID: 24366752.

Vavricka CJ, Liu Y, Kiyota H, et al. Influenza neuraminidase operates via a nucleophilic mechanism and can be targeted by covalent inhibitors. Nat Commun. 2013;4:1491. PMID: 23422659.

Hiasa M, Isoda Y, Kishimoto Y, et al. Inhibition of MAO-A and stimulation of behavioural activities in mice by the inactive prodrug form of the anti-influenza agent oseltamivir. Br J Pharmacol. 2013 May;169(1):115-29. PMID: 23320399.

Jefferson T, Jones MA, Doshi P, et al. Neuraminidase inhibitors for preventing and treating influenza in healthy adults and children. Cochrane Database Syst Rev. 2012 Jan 18;1:CD008965. PMID: 22258996.

" Not dangerous goods.

LKT O7218 Oseltamivir Phosphate 25 mg 159.4 Viral neuraminidase inhibitor, potential MAO-A inhibitor. 204255-11-8 ≥98% 410.4 C16H28N2O4 H3O4P CCC(CC)OC1C=C(CC(C1NC(=O)C)N)C(=O)OCC.OP(=O)(O)O Ambient 4°C "Huang L, Cao Y, Zhou J, et al. A conformational restriction in influenza A virus neuraminidase binding site by R152 caused the combinational effect of I222T with H274Y on oseltamivir resistance. Antimicrob Agents Chemother. 2013 Dec 23. [Epub ahead of print]. PMID: 24366752.

Vavricka CJ, Liu Y, Kiyota H, et al. Influenza neuraminidase operates via a nucleophilic mechanism and can be targeted by covalent inhibitors. Nat Commun. 2013;4:1491. PMID: 23422659.

Hiasa M, Isoda Y, Kishimoto Y, et al. Inhibition of MAO-A and stimulation of behavioural activities in mice by the inactive prodrug form of the anti-influenza agent oseltamivir. Br J Pharmacol. 2013 May;169(1):115-29. PMID: 23320399.

Jefferson T, Jones MA, Doshi P, et al. Neuraminidase inhibitors for preventing and treating influenza in healthy adults and children. Cochrane Database Syst Rev. 2012 Jan 18;1:CD008965. PMID: 22258996.

" Not dangerous goods.

LKT O7218 Oseltamivir Phosphate 100 mg 421.8 Viral neuraminidase inhibitor, potential MAO-A inhibitor. 204255-11-8 ≥98% 410.4 C16H28N2O4 H3O4P CCC(CC)OC1C=C(CC(C1NC(=O)C)N)C(=O)OCC.OP(=O)(O)O Ambient 4°C "Huang L, Cao Y, Zhou J, et al. A conformational restriction in influenza A virus neuraminidase binding site by R152 caused the combinational effect of I222T with H274Y on oseltamivir resistance. Antimicrob Agents Chemother. 2013 Dec 23. [Epub ahead of print]. PMID: 24366752.

Vavricka CJ, Liu Y, Kiyota H, et al. Influenza neuraminidase operates via a nucleophilic mechanism and can be targeted by covalent inhibitors. Nat Commun. 2013;4:1491. PMID: 23422659.

Hiasa M, Isoda Y, Kishimoto Y, et al. Inhibition of MAO-A and stimulation of behavioural activities in mice by the inactive prodrug form of the anti-influenza agent oseltamivir. Br J Pharmacol. 2013 May;169(1):115-29. PMID: 23320399.

Jefferson T, Jones MA, Doshi P, et al. Neuraminidase inhibitors for preventing and treating influenza in healthy adults and children. Cochrane Database Syst Rev. 2012 Jan 18;1:CD008965. PMID: 22258996.

" Not dangerous goods.

LKT S0033 Saikosaponin B2 1 mg 115.5 Saponin found in Bupleurum, Heteromorpha, and Scrophularia. ≥98% 780.98 C42H68O13 CC1C(C(C(C(O1)OC2CCC3(C(C2(C)CO)CCC4(C3C=CC56C4(CC(C7(C5CC(CC7)(C)C)CO6)O)C)C)C)O)OC8C(C(C(C(O8)CO)O)O)O)O Ambient -20°C Soluble in DMSO. "Cheng PW, Ng LT, Chiang LC, et al. Antiviral effects of saikosaponins on human coronavirus 229E in vitro. Clin Exp Pharmacol Physiol. 2006 Jul;33(7):612-6. PMID: 16789928.

Kyo R, Nakahata N, Kodama Y, et al. Antagonism of saikosaponin-induced prostaglandin E2 release by baicalein in C6 rat glioma cells. Biol Pharm Bull. 1999 Dec;22(12):1385-7. PMID: 10746176.

Zong Z, Fujikawa-Yamamoto K, Ota T, et al. Saikosaponin b2 induces differentiation without growth inhibition in cultured B16 melanoma cells. Cell Struct Funct. 1998 Oct;23(5):265-72. PMID: 9872567.

" None Not dangerous goods.

LKT S0033 Saikosaponin B2 5 mg 427.6 Saponin found in Bupleurum, Heteromorpha, and Scrophularia. ≥98% 780.98 C42H68O13 CC1C(C(C(C(O1)OC2CCC3(C(C2(C)CO)CCC4(C3C=CC56C4(CC(C7(C5CC(CC7)(C)C)CO6)O)C)C)C)O)OC8C(C(C(C(O8)CO)O)O)O)O Ambient -20°C Soluble in DMSO. "Cheng PW, Ng LT, Chiang LC, et al. Antiviral effects of saikosaponins on human coronavirus 229E in vitro. Clin Exp Pharmacol Physiol. 2006 Jul;33(7):612-6. PMID: 16789928.

Kyo R, Nakahata N, Kodama Y, et al. Antagonism of saikosaponin-induced prostaglandin E2 release by baicalein in C6 rat glioma cells. Biol Pharm Bull. 1999 Dec;22(12):1385-7. PMID: 10746176.

Zong Z, Fujikawa-Yamamoto K, Ota T, et al. Saikosaponin b2 induces differentiation without growth inhibition in cultured B16 melanoma cells. Cell Struct Funct. 1998 Oct;23(5):265-72. PMID: 9872567.

" None Not dangerous goods.

LKT O7377 Osthole 250 mg 94.4 O-methylated coumarin; Ca2+ channel blocker. "2H-1-Benzopyran-2-one, 7-methoxy-8-(3-methyl-2-butenyl)- 

(9CI) 

" Osthol; Ostol; Ostole. 484-12-8 ≥98% 244.29 C15H16O3 CC(=CCC1=C(C=CC2=C1OC(=O)C=C2)OC)C Ambient Ambient Practically insoluble in water. Soluble in aq alkalies, alcohol, chloroform or acetone. "Lin YC, Lin JC, Hung CM, et al. Osthole inhibits insulin-like growth factor-1-induced epithelial to mesenchymal transition via the inhibition of PI3K/Akt signaling pathway in human brain cancer cells. J Agric Food Chem. 2014 May 14. [Epub ahead of print]. PMID: 24828835.

Li Z, Ji H, Song X, et al. Osthole attenuates the development of carrageenan-induced lung inflammation in rats. Int Immunopharmacol. 2014 May;20(1):33-6. PMID: 24576740.

Mo LQ, Chen Y, Song L, et al. Osthole prevents intestinal ischemia-reperfusion-induced lung injury in a rodent model. J Surg Res. 2014 Mar 15. [Epub ahead of print]. PMID: 24726060.

Wang XY, Dong WP, Bi SH, et al. Protective effects of osthole against myocardial ischemia/reperfusion injury in rats. Int J Mol Med. 2013 Aug;32(2):365-72. PMID: 23695269.

Xu XM, Zhang Y, Qu D, et al. Osthole suppresses migration and invasion of A549 human lung cancer cells through inhibition of matrix metalloproteinase-2 and matrix metallopeptidase-9 in vitro. Mol Med Rep. 2012 Nov;6(5):1018-22. PMID: 22923177.

" None Not dangerous goods.

LKT O7377 Osthole 1 g 262.6 O-methylated coumarin; Ca2+ channel blocker. "2H-1-Benzopyran-2-one, 7-methoxy-8-(3-methyl-2-butenyl)- 

(9CI) 

" Osthol; Ostol; Ostole. 484-12-8 ≥98% 244.29 C15H16O3 CC(=CCC1=C(C=CC2=C1OC(=O)C=C2)OC)C Ambient Ambient Practically insoluble in water. Soluble in aq alkalies, alcohol, chloroform or acetone. "Lin YC, Lin JC, Hung CM, et al. Osthole inhibits insulin-like growth factor-1-induced epithelial to mesenchymal transition via the inhibition of PI3K/Akt signaling pathway in human brain cancer cells. J Agric Food Chem. 2014 May 14. [Epub ahead of print]. PMID: 24828835.

Li Z, Ji H, Song X, et al. Osthole attenuates the development of carrageenan-induced lung inflammation in rats. Int Immunopharmacol. 2014 May;20(1):33-6. PMID: 24576740.

Mo LQ, Chen Y, Song L, et al. Osthole prevents intestinal ischemia-reperfusion-induced lung injury in a rodent model. J Surg Res. 2014 Mar 15. [Epub ahead of print]. PMID: 24726060.

Wang XY, Dong WP, Bi SH, et al. Protective effects of osthole against myocardial ischemia/reperfusion injury in rats. Int J Mol Med. 2013 Aug;32(2):365-72. PMID: 23695269.

Xu XM, Zhang Y, Qu D, et al. Osthole suppresses migration and invasion of A549 human lung cancer cells through inhibition of matrix metalloproteinase-2 and matrix metallopeptidase-9 in vitro. Mol Med Rep. 2012 Nov;6(5):1018-22. PMID: 22923177.

" None Not dangerous goods.

LKT O7377 Osthole 5 g 1050.1 O-methylated coumarin; Ca2+ channel blocker. "2H-1-Benzopyran-2-one, 7-methoxy-8-(3-methyl-2-butenyl)- 

(9CI) 

" Osthol; Ostol; Ostole. 484-12-8 ≥98% 244.29 C15H16O3 CC(=CCC1=C(C=CC2=C1OC(=O)C=C2)OC)C Ambient Ambient Practically insoluble in water. Soluble in aq alkalies, alcohol, chloroform or acetone. "Lin YC, Lin JC, Hung CM, et al. Osthole inhibits insulin-like growth factor-1-induced epithelial to mesenchymal transition via the inhibition of PI3K/Akt signaling pathway in human brain cancer cells. J Agric Food Chem. 2014 May 14. [Epub ahead of print]. PMID: 24828835.

Li Z, Ji H, Song X, et al. Osthole attenuates the development of carrageenan-induced lung inflammation in rats. Int Immunopharmacol. 2014 May;20(1):33-6. PMID: 24576740.

Mo LQ, Chen Y, Song L, et al. Osthole prevents intestinal ischemia-reperfusion-induced lung injury in a rodent model. J Surg Res. 2014 Mar 15. [Epub ahead of print]. PMID: 24726060.

Wang XY, Dong WP, Bi SH, et al. Protective effects of osthole against myocardial ischemia/reperfusion injury in rats. Int J Mol Med. 2013 Aug;32(2):365-72. PMID: 23695269.

Xu XM, Zhang Y, Qu D, et al. Osthole suppresses migration and invasion of A549 human lung cancer cells through inhibition of matrix metalloproteinase-2 and matrix metallopeptidase-9 in vitro. Mol Med Rep. 2012 Nov;6(5):1018-22. PMID: 22923177.

" None Not dangerous goods.

LKT S0032 Saikosaponin B1 1 mg 115.5 Saponin found in Bupleurum, Heteromorpha, and Scrophularia. (3β,4α,16β)-16,23,28-trihydroxyoleana-11,13(18)- dien-3-yl-6-deoxy-3-O-β-D-glucopyranosyl-β-D- galacto-pyranoside 58558-08-0 ≥98% 780.98 C42H68O13 CC1C(C(C(C(O1)OC2C(C(OC(C2O)OC3CCC4(C(C3(C)CO)CCC5(C4C=CC6=C7CC(CCC7(C(CC65C)O)CO)(C)C)C)C)CO)O)O)O)O Ambient -20°C Soluble in DMSO. Kyo R, Nakahata N, Kodama Y, et al. Antagonism of saikosaponin-induced prostaglandin E2 release by baicalein in C6 rat glioma cells. Biol Pharm Bull. 1999 Dec;22(12):1385-7. PMID: 10746176. Not dangerous goods.

LKT S0032 Saikosaponin B1 5 mg 427.6 Saponin found in Bupleurum, Heteromorpha, and Scrophularia. (3β,4α,16β)-16,23,28-trihydroxyoleana-11,13(18)- dien-3-yl-6-deoxy-3-O-β-D-glucopyranosyl-β-D- galacto-pyranoside 58558-08-0 ≥98% 780.98 C42H68O13 CC1C(C(C(C(O1)OC2C(C(OC(C2O)OC3CCC4(C(C3(C)CO)CCC5(C4C=CC6=C7CC(CCC7(C(CC65C)O)CO)(C)C)C)C)CO)O)O)O)O Ambient -20°C Soluble in DMSO. Kyo R, Nakahata N, Kodama Y, et al. Antagonism of saikosaponin-induced prostaglandin E2 release by baicalein in C6 rat glioma cells. Biol Pharm Bull. 1999 Dec;22(12):1385-7. PMID: 10746176. Not dangerous goods.

LKT O8500 Ovalbumin Fragment (257-264) 1 mg 201.8 OVA antigen. albumin; OVA (257-264) ≥98% 963.2 C45H74N10O13 Stable. Ambient -20°C Moderately soluble in water. "Cheng WK, Wee K, Kollmann TR, et al. Topical CpG adjuvantation of a protein-based vaccine induces protective immunity to Listeria monocytogenes. Clin Vaccine Immunol. 2014 Mar;21(3):329-39. PMID: 24391136.

Xie Y, Wang L, Freywald A, et al. A novel T cell-based vaccine capable of stimulating long-term functional CTL memory against B16 melanoma via CD40L signaling. Cell Mol Immunol. 2013 Jan;10(1):72-7. PMID: 23042534.

Denton AE, Wesselingh R, Gras S, et al. Affinity thresholds for naive CD8+ CTL activation by peptides and engineered influenza A viruses. J Immunol. 2011 Dec 1;187(11):5733-44. PMID: 22039305.

Jameson SC, Bevan MJ. Dissection of major histocompatibility complex (MHC) and T cell receptor contact residues in a Kb-restricted ovalbumin peptide and an assessment of the predictive power of MHC-binding motifs. Eur J Immunol. 1992 Oct;22(10):2663-7. PMID: 1396971.

" Xn T Xi Muta Not dangerous goods.

LKT O8503 Ovalbumin Fragment (323-339) 5 mg 856.9 OVA antigen. OVA (323-339) ≥98% 1773.9 C74H120N26O25 Ambient -20°C "Nakajima-Adachi H, Koike E, Totsuka M, et al. Two distinct epitopes on the ovalbumin 323-339 peptide differentiating CD4+ T cells into the Th2 or Th1 phenotype. Biosci Biotechnol Biochem. 2012;76(10):1979-81. PMID: 23047087.

Ichikawa K, Kagamu H, Koyama K, et al. Epitope diversification driven by non-tumor epitope-specific Th1 and Th17 mediates potent antitumor reactivity. Vaccine. 2012 Sep 21;30(43):6190-7. PMID: 22889826.

Sun LZ, Elsayed S, Aasen TB, et al. Comparison between ovalbumin and ovalbumin peptide 323-339 responses in allergic mice: humoral and cellular aspects. Scand J Immunol. 2010 May;71(5):329-35. PMID: 20500683.

" Not dangerous goods.

LKT S0006 S6-1 1 mg 83.9 Peptide, involved in insulin sensitivity. RRLSSLRA 93674-74-9 ≥95% 958.14 C39H75N17O11 Ambient -20°C "Nakagawa M, Ohmido N, Ishikawa K, et al. Anti-peptide antibodies for examining the conformation, molecular assembly and localization of an intracellular protein, ribosomal protein S6, in vivo. J Biochem. 2008 Mar;143(3):325-32. PMID: 18039684.

Hecht LB, Straus DS. Insulin-sensitive, serum-sensitive protein kinase activity that phosphorylates ribosomal protein S6 in cultured fibroblast-melanoma hybrid cells. Endocrinology. 1986 Aug;119(2):470-80. PMID: 3525118.

"

LKT O9201 Oxaliplatin 5 mg 54.4 Pt-based DNA cross-linker. (SP-4-2)-[(1R,2R)-1.2-Cyclohexanediamine-κN,κN']- [ethanedioato(2-)-κO1,κO2]platinum Oxalatoplatin; Oxalatoplatinum 61825-94-3 ≥98% 397.29 C8H14N2O4Pt C1CCC(C(C1)N)N.C(=O)(C(=O)O)O.[Pt] Ambient -20°C Soluble in water (10 mM, 4 mg/mL), DMSO (50 mM or 20 mg /mL). "Chen X, Wu Y, Dong H, et al. Platinum-based agents for individualized cancer treatment. Curr Mol Med. 2013 Dec;13(10):1603-12. PMID: 24206132.

Gao J, Wang R, Yang Q, et al. Effect of Oxaliplatin on cell cycle of hepatocellular carcinoma cell line HepG2. Zhejiang Da Xue Xue Bao Yi Xue Ban. 2013 Jul;42(4):437-42. PMID: 24022933.

Graham J, Mushin M, Kirkpatrick P. Oxaliplatin. Nat Rev Drug Discov. 2004 Jan;3(1):11-2. PMID: 14756144.

" Xi, Carc. Not dangerous goods.

LKT O9201 Oxaliplatin 25 mg 163.2 Pt-based DNA cross-linker. (SP-4-2)-[(1R,2R)-1.2-Cyclohexanediamine-κN,κN']- [ethanedioato(2-)-κO1,κO2]platinum Oxalatoplatin; Oxalatoplatinum 61825-94-3 ≥98% 397.29 C8H14N2O4Pt C1CCC(C(C1)N)N.C(=O)(C(=O)O)O.[Pt] Ambient -20°C Soluble in water (10 mM, 4 mg/mL), DMSO (50 mM or 20 mg /mL). "Chen X, Wu Y, Dong H, et al. Platinum-based agents for individualized cancer treatment. Curr Mol Med. 2013 Dec;13(10):1603-12. PMID: 24206132.

Gao J, Wang R, Yang Q, et al. Effect of Oxaliplatin on cell cycle of hepatocellular carcinoma cell line HepG2. Zhejiang Da Xue Xue Bao Yi Xue Ban. 2013 Jul;42(4):437-42. PMID: 24022933.

Graham J, Mushin M, Kirkpatrick P. Oxaliplatin. Nat Rev Drug Discov. 2004 Jan;3(1):11-2. PMID: 14756144.

" Xi, Carc. Not dangerous goods.

LKT S0006 S6-1 2 mg 144 Peptide, involved in insulin sensitivity. RRLSSLRA 93674-74-9 ≥95% 958.14 C39H75N17O11 Ambient -20°C "Nakagawa M, Ohmido N, Ishikawa K, et al. Anti-peptide antibodies for examining the conformation, molecular assembly and localization of an intracellular protein, ribosomal protein S6, in vivo. J Biochem. 2008 Mar;143(3):325-32. PMID: 18039684.

Hecht LB, Straus DS. Insulin-sensitive, serum-sensitive protein kinase activity that phosphorylates ribosomal protein S6 in cultured fibroblast-melanoma hybrid cells. Endocrinology. 1986 Aug;119(2):470-80. PMID: 3525118.

"

LKT O9201 Oxaliplatin 100 mg 339.8 Pt-based DNA cross-linker. (SP-4-2)-[(1R,2R)-1.2-Cyclohexanediamine-κN,κN']- [ethanedioato(2-)-κO1,κO2]platinum Oxalatoplatin; Oxalatoplatinum 61825-94-3 ≥98% 397.29 C8H14N2O4Pt C1CCC(C(C1)N)N.C(=O)(C(=O)O)O.[Pt] Ambient -20°C Soluble in water (10 mM, 4 mg/mL), DMSO (50 mM or 20 mg /mL). "Chen X, Wu Y, Dong H, et al. Platinum-based agents for individualized cancer treatment. Curr Mol Med. 2013 Dec;13(10):1603-12. PMID: 24206132.

Gao J, Wang R, Yang Q, et al. Effect of Oxaliplatin on cell cycle of hepatocellular carcinoma cell line HepG2. Zhejiang Da Xue Xue Bao Yi Xue Ban. 2013 Jul;42(4):437-42. PMID: 24022933.

Graham J, Mushin M, Kirkpatrick P. Oxaliplatin. Nat Rev Drug Discov. 2004 Jan;3(1):11-2. PMID: 14756144.

" Xi, Carc. Not dangerous goods.

LKT S0006 S6-1 5 mg 252.1 Peptide, involved in insulin sensitivity. RRLSSLRA 93674-74-9 ≥95% 958.14 C39H75N17O11 Ambient -20°C "Nakagawa M, Ohmido N, Ishikawa K, et al. Anti-peptide antibodies for examining the conformation, molecular assembly and localization of an intracellular protein, ribosomal protein S6, in vivo. J Biochem. 2008 Mar;143(3):325-32. PMID: 18039684.

Hecht LB, Straus DS. Insulin-sensitive, serum-sensitive protein kinase activity that phosphorylates ribosomal protein S6 in cultured fibroblast-melanoma hybrid cells. Endocrinology. 1986 Aug;119(2):470-80. PMID: 3525118.

"

LKT O9234 Oxiconazole Nitrate 1 g 92.5 Imidazole; 14-α demethylase inhibitor. (Z)-1-(2,4-Dichloropheyl)-2-(1H-imidazol-1-yl)- ethenone O-[(2,4)-dichlorophenyl)methyl]oxime mononitrate Oxistat; Myfungar; Oceral 64211-46-7 ≥98% 492.15 C18H13Cl4N3O HNO3 C1=CC(=C(C=C1Cl)Cl)CON=C(CN2C=CN=C2)C3=C(C=C(C=C3)Cl)Cl.[N+](=O)(O)[O-] Ambient Ambient Soluble in methanol. "Kalra MG, Higgins KE, Kinney BS. Intertrigo and secondary skin infections. Am Fam Physician. 2014 Apr 1;89(7):569-73. PMID: 24695603.

Jerajani HR, Amladi ST, Bongale R, et al. Evaluation of clinical efficacy and safety of once daily topical administration of 1% oxiconazole cream and lotion in dermatophytosis : an open label, non comparative multicentre study. Indian J Dermatol Venereol Leprol. 2000 Jul-Aug;66(4):188-92. PMID: 20877072.

Gebre-Hiwot A, Frommel D. The in-vitro anti-leishmanial activity of inhibitors of ergosterol biosynthesis. J Antimicrob Chemother. 1993 Dec;32(6):837-42. PMID: 8144423.

" Not dangerous goods.

LKT O9234 Oxiconazole Nitrate 5 g 277.4 Imidazole; 14-α demethylase inhibitor. (Z)-1-(2,4-Dichloropheyl)-2-(1H-imidazol-1-yl)- ethenone O-[(2,4)-dichlorophenyl)methyl]oxime mononitrate Oxistat; Myfungar; Oceral 64211-46-7 ≥98% 492.15 C18H13Cl4N3O HNO3 C1=CC(=C(C=C1Cl)Cl)CON=C(CN2C=CN=C2)C3=C(C=C(C=C3)Cl)Cl.[N+](=O)(O)[O-] Ambient Ambient Soluble in methanol. "Kalra MG, Higgins KE, Kinney BS. Intertrigo and secondary skin infections. Am Fam Physician. 2014 Apr 1;89(7):569-73. PMID: 24695603.

Jerajani HR, Amladi ST, Bongale R, et al. Evaluation of clinical efficacy and safety of once daily topical administration of 1% oxiconazole cream and lotion in dermatophytosis : an open label, non comparative multicentre study. Indian J Dermatol Venereol Leprol. 2000 Jul-Aug;66(4):188-92. PMID: 20877072.

Gebre-Hiwot A, Frommel D. The in-vitro anti-leishmanial activity of inhibitors of ergosterol biosynthesis. J Antimicrob Chemother. 1993 Dec;32(6):837-42. PMID: 8144423.

" Not dangerous goods.

LKT O9234 Oxiconazole Nitrate 25 g 924 Imidazole; 14-α demethylase inhibitor. (Z)-1-(2,4-Dichloropheyl)-2-(1H-imidazol-1-yl)- ethenone O-[(2,4)-dichlorophenyl)methyl]oxime mononitrate Oxistat; Myfungar; Oceral 64211-46-7 ≥98% 492.15 C18H13Cl4N3O HNO3 C1=CC(=C(C=C1Cl)Cl)CON=C(CN2C=CN=C2)C3=C(C=C(C=C3)Cl)Cl.[N+](=O)(O)[O-] Ambient Ambient Soluble in methanol. "Kalra MG, Higgins KE, Kinney BS. Intertrigo and secondary skin infections. Am Fam Physician. 2014 Apr 1;89(7):569-73. PMID: 24695603.

Jerajani HR, Amladi ST, Bongale R, et al. Evaluation of clinical efficacy and safety of once daily topical administration of 1% oxiconazole cream and lotion in dermatophytosis : an open label, non comparative multicentre study. Indian J Dermatol Venereol Leprol. 2000 Jul-Aug;66(4):188-92. PMID: 20877072.

Gebre-Hiwot A, Frommel D. The in-vitro anti-leishmanial activity of inhibitors of ergosterol biosynthesis. J Antimicrob Chemother. 1993 Dec;32(6):837-42. PMID: 8144423.

" Not dangerous goods.

LKT O9256 16-Oxocafestol 25 mg 200.6 Synthetic cafestol derivative. 108664-98-8 ≥97% 284.39 C19H24O2 CC12CCC3=C(C1CCC45C2CCC(C4)C(=O)C5)C=CO3 Ambient -20°C Soluble in water. Lam LK, Sparnins VL, Wattenberg LW. Effects of derivatives of kahweol and cafestol on the activity of glutathione S-transferase in mice. J Med Chem. 1987 Aug;30(8):1399-403. PMID: 3612687. Not dangerous goods.

LKT O9256 16-Oxocafestol 50 mg 349.8 Synthetic cafestol derivative. 108664-98-8 ≥97% 284.39 C19H24O2 CC12CCC3=C(C1CCC45C2CCC(C4)C(=O)C5)C=CO3 Ambient -20°C Soluble in water. Lam LK, Sparnins VL, Wattenberg LW. Effects of derivatives of kahweol and cafestol on the activity of glutathione S-transferase in mice. J Med Chem. 1987 Aug;30(8):1399-403. PMID: 3612687. Not dangerous goods.

LKT O9256 16-Oxocafestol 100 mg 602.5 Synthetic cafestol derivative. 108664-98-8 ≥97% 284.39 C19H24O2 CC12CCC3=C(C1CCC45C2CCC(C4)C(=O)C5)C=CO3 Ambient -20°C Soluble in water. Lam LK, Sparnins VL, Wattenberg LW. Effects of derivatives of kahweol and cafestol on the activity of glutathione S-transferase in mice. J Med Chem. 1987 Aug;30(8):1399-403. PMID: 3612687. Not dangerous goods.

LKT O9256 16-Oxocafestol 500 mg 1959.2 Synthetic cafestol derivative. 108664-98-8 ≥97% 284.39 C19H24O2 CC12CCC3=C(C1CCC45C2CCC(C4)C(=O)C5)C=CO3 Ambient -20°C Soluble in water. Lam LK, Sparnins VL, Wattenberg LW. Effects of derivatives of kahweol and cafestol on the activity of glutathione S-transferase in mice. J Med Chem. 1987 Aug;30(8):1399-403. PMID: 3612687. Not dangerous goods.

LKT O9257 16-Oxokahweol 10 mg 241 Synthetic kahweol derivative. 108664-99-9 ≥95% 282.39 C19H22O2 CC12C=CC3=C(C1CCC45C2CCC(C4)C(=O)C5)C=CO3 Ambient -20°C Soluble in water. Lam LK, Sparnins VL, Wattenberg LW. Effects of derivatives of kahweol and cafestol on the activity of glutathione S-transferase in mice. J Med Chem. 1987 Aug;30(8):1399-403. PMID: 3612687. Not dangerous goods.

LKT O9257 16-Oxokahweol 25 mg 514.2 Synthetic kahweol derivative. 108664-99-9 ≥95% 282.39 C19H22O2 CC12C=CC3=C(C1CCC45C2CCC(C4)C(=O)C5)C=CO3 Ambient -20°C Soluble in water. Lam LK, Sparnins VL, Wattenberg LW. Effects of derivatives of kahweol and cafestol on the activity of glutathione S-transferase in mice. J Med Chem. 1987 Aug;30(8):1399-403. PMID: 3612687. Not dangerous goods.

LKT O9257 16-Oxokahweol 50 mg 875 Synthetic kahweol derivative. 108664-99-9 ≥95% 282.39 C19H22O2 CC12C=CC3=C(C1CCC45C2CCC(C4)C(=O)C5)C=CO3 Ambient -20°C Soluble in water. Lam LK, Sparnins VL, Wattenberg LW. Effects of derivatives of kahweol and cafestol on the activity of glutathione S-transferase in mice. J Med Chem. 1987 Aug;30(8):1399-403. PMID: 3612687. Not dangerous goods.

LKT O9257 16-Oxokahweol 100 mg 1484.9 Synthetic kahweol derivative. 108664-99-9 ≥95% 282.39 C19H22O2 CC12C=CC3=C(C1CCC45C2CCC(C4)C(=O)C5)C=CO3 Ambient -20°C Soluble in water. Lam LK, Sparnins VL, Wattenberg LW. Effects of derivatives of kahweol and cafestol on the activity of glutathione S-transferase in mice. J Med Chem. 1987 Aug;30(8):1399-403. PMID: 3612687. Not dangerous goods.

LKT O9302 Oxacillin Sodium Monohydrate 1 g 33.9 β-lactam; penicillin binding protein inhibitor. "(2S,5R,6R)-3,3-Dimethyl-6-[[(5-methyl-3-phenyl-4-

isoxazolyl)carbonyl]amino]-7-oxo-4-thia-1-aza- bicyclo[3.2.0]heptane-2-carboxylic acid monosodium salt" Penicillin P-12; Bactocill; Bristopen; Cryptocillin; Micropenin 7240-38-2 ≥98% 441.44 C19H18N3NaO5S H2O CC1=C(C(=NO1)C2=CC=CC=C2)C(=O)NC3C4N(C3=O)C(C(S4)(C)C)C(=O)[O-].[Na+] Ambient Ambient Solublr in water. "Werth BJ, Vidaillac C, Murray KP, et al. Novel combinations of vancomycin plus ceftaroline or oxacillin against methicillin-resistant vancomycin-intermediate Staphylococcus aureus (VISA) and heterogeneous VISA. Antimicrob Agents Chemother. 2013 May;57(5):2376-9. PMID: 23422917.

Chung M, Antignac A, Kim C, et al. Comparative study of the susceptibilities of major epidemic clones of methicillin-resistant Staphylococcus aureus to oxacillin and to the new broad-spectrum cephalosporin ceftobiprole. Antimicrob Agents Chemother. 2008 Aug;52(8):2709-17. PMID: 18505853.

" Xi Not dangerous goods.

LKT O9302 Oxacillin Sodium Monohydrate 5 g 108.8 β-lactam; penicillin binding protein inhibitor. "(2S,5R,6R)-3,3-Dimethyl-6-[[(5-methyl-3-phenyl-4-

isoxazolyl)carbonyl]amino]-7-oxo-4-thia-1-aza- bicyclo[3.2.0]heptane-2-carboxylic acid monosodium salt" Penicillin P-12; Bactocill; Bristopen; Cryptocillin; Micropenin 7240-38-2 ≥98% 441.44 C19H18N3NaO5S H2O CC1=C(C(=NO1)C2=CC=CC=C2)C(=O)NC3C4N(C3=O)C(C(S4)(C)C)C(=O)[O-].[Na+] Ambient Ambient Solublr in water. "Werth BJ, Vidaillac C, Murray KP, et al. Novel combinations of vancomycin plus ceftaroline or oxacillin against methicillin-resistant vancomycin-intermediate Staphylococcus aureus (VISA) and heterogeneous VISA. Antimicrob Agents Chemother. 2013 May;57(5):2376-9. PMID: 23422917.

Chung M, Antignac A, Kim C, et al. Comparative study of the susceptibilities of major epidemic clones of methicillin-resistant Staphylococcus aureus to oxacillin and to the new broad-spectrum cephalosporin ceftobiprole. Antimicrob Agents Chemother. 2008 Aug;52(8):2709-17. PMID: 18505853.

" Xi Not dangerous goods.

LKT O9302 Oxacillin Sodium Monohydrate 25 g 380.5 β-lactam; penicillin binding protein inhibitor. "(2S,5R,6R)-3,3-Dimethyl-6-[[(5-methyl-3-phenyl-4-

isoxazolyl)carbonyl]amino]-7-oxo-4-thia-1-aza- bicyclo[3.2.0]heptane-2-carboxylic acid monosodium salt" Penicillin P-12; Bactocill; Bristopen; Cryptocillin; Micropenin 7240-38-2 ≥98% 441.44 C19H18N3NaO5S H2O CC1=C(C(=NO1)C2=CC=CC=C2)C(=O)NC3C4N(C3=O)C(C(S4)(C)C)C(=O)[O-].[Na+] Ambient Ambient Solublr in water. "Werth BJ, Vidaillac C, Murray KP, et al. Novel combinations of vancomycin plus ceftaroline or oxacillin against methicillin-resistant vancomycin-intermediate Staphylococcus aureus (VISA) and heterogeneous VISA. Antimicrob Agents Chemother. 2013 May;57(5):2376-9. PMID: 23422917.

Chung M, Antignac A, Kim C, et al. Comparative study of the susceptibilities of major epidemic clones of methicillin-resistant Staphylococcus aureus to oxacillin and to the new broad-spectrum cephalosporin ceftobiprole. Antimicrob Agents Chemother. 2008 Aug;52(8):2709-17. PMID: 18505853.

" Xi Not dangerous goods.

LKT O9322 Oxfendazole 10 g 81 Benzimidazole; microtubule polymerization inhibitor. [5-(Phenylsulfinyl)-1H-benzimidazol-2-yl]carbamic acid methyl ester Repidose; Systamex 53716-50-0 ≥98% 315.35 C15H13N3O3S COC(=O)NC1=NC2=C(N1)C=C(C=C2)S(=O)C3=CC=CC=C3 Ambient Ambient Insoluble in water. Slightly soluble in acetone, chloroform, ether and methanol. "Ortiz P, Terrones S, Cabrera M, et al. Oxfendazole flukicidal activity in pigs. Acta Trop. 2014 Aug;136:10-3. PMID: 24713198.

Mkupasi EM, Ngowi HA, Sikasunge CS, et al. Efficacy of ivermectin and oxfendazole against Taenia solium cysticercosis and other parasitoses in naturally infected pigs. Acta Trop. 2013 Oct;128(1):48-53. PMID: 23806569.

" Not dangerous goods.

LKT O9322 Oxfendazole 25 g 173.3 Benzimidazole; microtubule polymerization inhibitor. [5-(Phenylsulfinyl)-1H-benzimidazol-2-yl]carbamic acid methyl ester Repidose; Systamex 53716-50-0 ≥98% 315.35 C15H13N3O3S COC(=O)NC1=NC2=C(N1)C=C(C=C2)S(=O)C3=CC=CC=C3 Ambient Ambient Insoluble in water. Slightly soluble in acetone, chloroform, ether and methanol. "Ortiz P, Terrones S, Cabrera M, et al. Oxfendazole flukicidal activity in pigs. Acta Trop. 2014 Aug;136:10-3. PMID: 24713198.

Mkupasi EM, Ngowi HA, Sikasunge CS, et al. Efficacy of ivermectin and oxfendazole against Taenia solium cysticercosis and other parasitoses in naturally infected pigs. Acta Trop. 2013 Oct;128(1):48-53. PMID: 23806569.

" Not dangerous goods.

LKT O9322 Oxfendazole 100 g 543.1 Benzimidazole; microtubule polymerization inhibitor. [5-(Phenylsulfinyl)-1H-benzimidazol-2-yl]carbamic acid methyl ester Repidose; Systamex 53716-50-0 ≥98% 315.35 C15H13N3O3S COC(=O)NC1=NC2=C(N1)C=C(C=C2)S(=O)C3=CC=CC=C3 Ambient Ambient Insoluble in water. Slightly soluble in acetone, chloroform, ether and methanol. "Ortiz P, Terrones S, Cabrera M, et al. Oxfendazole flukicidal activity in pigs. Acta Trop. 2014 Aug;136:10-3. PMID: 24713198.

Mkupasi EM, Ngowi HA, Sikasunge CS, et al. Efficacy of ivermectin and oxfendazole against Taenia solium cysticercosis and other parasitoses in naturally infected pigs. Acta Trop. 2013 Oct;128(1):48-53. PMID: 23806569.

" Not dangerous goods.

LKT O9334 Oxibendazole 5 g 81 Benzimidazole; microtubule polymerization inhibitor. (5-propoxy-1H-benzimidazol-2-yl) carbamic acid methyl ester Equitac; SKF-30310; Anthelcide EQ 20559-55-1 ≥98% 249.27 C12H15N3O3 CCCOC1=CC2=C(C=C1)N=C(N2)NC(=O)OC Ambient Ambient Insoluble in water. Soluble in acetic acid and formic acid. "Nielsen MK, Betancourt A, Lyons ET, et al. Characterization of the inflammatory response to anthelmintic treatment of ponies with cyathostominosis. Vet J. 2013 Nov;198(2):457-62. PMID: 24035469.

Traversa D, Iorio R, Otranto D, et al. Species-specific identification of equine cyathostomes resistant to fenbendazole and susceptible to oxibendazole and moxidectin by macroarray probing. Exp Parasitol. 2009 Jan;121(1):92-5. PMID: 18950625.

Kates KC, Colglazier ML, Enzie FD. Oxibendazole: critical anthelmintic trials in equids. Vet Rec. 1975 Dec 6;97(23):442-4. PMID: 1216434.

" None Not dangerous goods.

LKT O9334 Oxibendazole 10 g 138.9 Benzimidazole; microtubule polymerization inhibitor. (5-propoxy-1H-benzimidazol-2-yl) carbamic acid methyl ester Equitac; SKF-30310; Anthelcide EQ 20559-55-1 ≥98% 249.27 C12H15N3O3 CCCOC1=CC2=C(C=C1)N=C(N2)NC(=O)OC Ambient Ambient Insoluble in water. Soluble in acetic acid and formic acid. "Nielsen MK, Betancourt A, Lyons ET, et al. Characterization of the inflammatory response to anthelmintic treatment of ponies with cyathostominosis. Vet J. 2013 Nov;198(2):457-62. PMID: 24035469.

Traversa D, Iorio R, Otranto D, et al. Species-specific identification of equine cyathostomes resistant to fenbendazole and susceptible to oxibendazole and moxidectin by macroarray probing. Exp Parasitol. 2009 Jan;121(1):92-5. PMID: 18950625.

Kates KC, Colglazier ML, Enzie FD. Oxibendazole: critical anthelmintic trials in equids. Vet Rec. 1975 Dec 6;97(23):442-4. PMID: 1216434.

" None Not dangerous goods.

LKT O9334 Oxibendazole 25 g 288.8 Benzimidazole; microtubule polymerization inhibitor. (5-propoxy-1H-benzimidazol-2-yl) carbamic acid methyl ester Equitac; SKF-30310; Anthelcide EQ 20559-55-1 ≥98% 249.27 C12H15N3O3 CCCOC1=CC2=C(C=C1)N=C(N2)NC(=O)OC Ambient Ambient Insoluble in water. Soluble in acetic acid and formic acid. "Nielsen MK, Betancourt A, Lyons ET, et al. Characterization of the inflammatory response to anthelmintic treatment of ponies with cyathostominosis. Vet J. 2013 Nov;198(2):457-62. PMID: 24035469.

Traversa D, Iorio R, Otranto D, et al. Species-specific identification of equine cyathostomes resistant to fenbendazole and susceptible to oxibendazole and moxidectin by macroarray probing. Exp Parasitol. 2009 Jan;121(1):92-5. PMID: 18950625.

Kates KC, Colglazier ML, Enzie FD. Oxibendazole: critical anthelmintic trials in equids. Vet Rec. 1975 Dec 6;97(23):442-4. PMID: 1216434.

" None Not dangerous goods.

LKT O9396 Oxytetracycline 10 g 27.8 Tetracycline; protein translation inhibitor. [4S-(4α,,4aα,5α,,5aα,,6β,12aα,)]-4-(Dimethylamino)-1,4,4a,5,5a,6,11,12a-octahydrothacenecarboxamide Adamycin; Geotilin;Terramycin  79-57-2 ≥96% 460.43 C22H24N2O9 CC1(C2C(C3C(C(=O)C(=C(C3(C(=O)C2=C(C4=C1C=CC=C4O)O)O)O)C(=O)N)N(C)C)O)O Ambient 4°C Insoluble in water (~0.24 mg/mL). Ethanol (15 mg/mL). "Strobel H, Lauseker M, Forbes AB. Targeted antibiotic treatment of lame sheep with footrot using either oxytetracycline or gamithromycin. Vet Rec. 2014 Jan 11;174(2):46. PMID: 24362004.

Shao J, Feng G. Selective killing effect of oxytetracycline, propafenone and metamizole on A549 or Hela cells. Chin J Cancer Res. 2013 Dec;25(6):662-70. PMID: 24385693.

Strel'tsov SA, Kukhanova MK, Gurskiĭ GV, et al. Oxytetracycline binding to E. coli ribosomes. Mol Biol (Mosk). 1975 Nov-Dec;9(6):910-21. PMID: 778591.

" Repr., Xi Not dangerous goods.

LKT O9396 Oxytetracycline 50 g 104.3 Tetracycline; protein translation inhibitor. [4S-(4α,,4aα,5α,,5aα,,6β,12aα,)]-4-(Dimethylamino)-1,4,4a,5,5a,6,11,12a-octahydrothacenecarboxamide Adamycin; Geotilin;Terramycin  79-57-2 ≥96% 460.43 C22H24N2O9 CC1(C2C(C3C(C(=O)C(=C(C3(C(=O)C2=C(C4=C1C=CC=C4O)O)O)O)C(=O)N)N(C)C)O)O Ambient 4°C Insoluble in water (~0.24 mg/mL). Ethanol (15 mg/mL). "Strobel H, Lauseker M, Forbes AB. Targeted antibiotic treatment of lame sheep with footrot using either oxytetracycline or gamithromycin. Vet Rec. 2014 Jan 11;174(2):46. PMID: 24362004.

Shao J, Feng G. Selective killing effect of oxytetracycline, propafenone and metamizole on A549 or Hela cells. Chin J Cancer Res. 2013 Dec;25(6):662-70. PMID: 24385693.

Strel'tsov SA, Kukhanova MK, Gurskiĭ GV, et al. Oxytetracycline binding to E. coli ribosomes. Mol Biol (Mosk). 1975 Nov-Dec;9(6):910-21. PMID: 778591.

" Repr., Xi Not dangerous goods.

LKT O9396 Oxytetracycline 100 g 194 Tetracycline; protein translation inhibitor. [4S-(4α,,4aα,5α,,5aα,,6β,12aα,)]-4-(Dimethylamino)-1,4,4a,5,5a,6,11,12a-octahydrothacenecarboxamide Adamycin; Geotilin;Terramycin  79-57-2 ≥96% 460.43 C22H24N2O9 CC1(C2C(C3C(C(=O)C(=C(C3(C(=O)C2=C(C4=C1C=CC=C4O)O)O)O)C(=O)N)N(C)C)O)O Ambient 4°C Insoluble in water (~0.24 mg/mL). Ethanol (15 mg/mL). "Strobel H, Lauseker M, Forbes AB. Targeted antibiotic treatment of lame sheep with footrot using either oxytetracycline or gamithromycin. Vet Rec. 2014 Jan 11;174(2):46. PMID: 24362004.

Shao J, Feng G. Selective killing effect of oxytetracycline, propafenone and metamizole on A549 or Hela cells. Chin J Cancer Res. 2013 Dec;25(6):662-70. PMID: 24385693.

Strel'tsov SA, Kukhanova MK, Gurskiĭ GV, et al. Oxytetracycline binding to E. coli ribosomes. Mol Biol (Mosk). 1975 Nov-Dec;9(6):910-21. PMID: 778591.

" Repr., Xi Not dangerous goods.

LKT O9397 Oxytetracycline Hydrochloride 10 g 27.8 Tetracycline; protein translation inhibitor. "4-(Dimethylamino)-1,4,4a,5,5a,6,11,12a-octahydro-

3,5,6,10,12,12a-hexahydroxy-6-methyl-1,11-dioxo-2-

naphthacenecarboxamide monohydrochloride" Alamycin; Hydrocyclin; Oxacycline; Tetran hydrochloride    2058-46-0 ≥96% 496.93 C22H24N2O9 HCl CC1(C2C(C3C(C(=O)C(=C(C3(C(=O)C2=C(C4=C1C=CC=C4O)O)O)O)C(=O)N)N(C)C)O)O.Cl Ambient Ambient Soluble in water (1g/mL) and 95% ethanol. "Strobel H, Lauseker M, Forbes AB. Targeted antibiotic treatment of lame sheep with footrot using either oxytetracycline or gamithromycin. Vet Rec. 2014 Jan 11;174(2):46. PMID: 24362004.

Shao J, Feng G. Selective killing effect of oxytetracycline, propafenone and metamizole on A549 or Hela cells. Chin J Cancer Res. 2013 Dec;25(6):662-70. PMID: 24385693.

Strel'tsov SA, Kukhanova MK, Gurskiĭ GV, et al. Oxytetracycline binding to E. coli ribosomes. Mol Biol (Mosk). 1975 Nov-Dec;9(6):910-21. PMID: 778591.

" Repr., Xi Not dangerous goods.

LKT O9397 Oxytetracycline Hydrochloride 50 g 104.3 Tetracycline; protein translation inhibitor. "4-(Dimethylamino)-1,4,4a,5,5a,6,11,12a-octahydro-

3,5,6,10,12,12a-hexahydroxy-6-methyl-1,11-dioxo-2-

naphthacenecarboxamide monohydrochloride" Alamycin; Hydrocyclin; Oxacycline; Tetran hydrochloride    2058-46-0 ≥96% 496.93 C22H24N2O9 HCl CC1(C2C(C3C(C(=O)C(=C(C3(C(=O)C2=C(C4=C1C=CC=C4O)O)O)O)C(=O)N)N(C)C)O)O.Cl Ambient Ambient Soluble in water (1g/mL) and 95% ethanol. "Strobel H, Lauseker M, Forbes AB. Targeted antibiotic treatment of lame sheep with footrot using either oxytetracycline or gamithromycin. Vet Rec. 2014 Jan 11;174(2):46. PMID: 24362004.

Shao J, Feng G. Selective killing effect of oxytetracycline, propafenone and metamizole on A549 or Hela cells. Chin J Cancer Res. 2013 Dec;25(6):662-70. PMID: 24385693.

Strel'tsov SA, Kukhanova MK, Gurskiĭ GV, et al. Oxytetracycline binding to E. coli ribosomes. Mol Biol (Mosk). 1975 Nov-Dec;9(6):910-21. PMID: 778591.

" Repr., Xi Not dangerous goods.

LKT O9397 Oxytetracycline Hydrochloride 100 g 184.8 Tetracycline; protein translation inhibitor. "4-(Dimethylamino)-1,4,4a,5,5a,6,11,12a-octahydro-

3,5,6,10,12,12a-hexahydroxy-6-methyl-1,11-dioxo-2-

naphthacenecarboxamide monohydrochloride" Alamycin; Hydrocyclin; Oxacycline; Tetran hydrochloride    2058-46-0 ≥96% 496.93 C22H24N2O9 HCl CC1(C2C(C3C(C(=O)C(=C(C3(C(=O)C2=C(C4=C1C=CC=C4O)O)O)O)C(=O)N)N(C)C)O)O.Cl Ambient Ambient Soluble in water (1g/mL) and 95% ethanol. "Strobel H, Lauseker M, Forbes AB. Targeted antibiotic treatment of lame sheep with footrot using either oxytetracycline or gamithromycin. Vet Rec. 2014 Jan 11;174(2):46. PMID: 24362004.

Shao J, Feng G. Selective killing effect of oxytetracycline, propafenone and metamizole on A549 or Hela cells. Chin J Cancer Res. 2013 Dec;25(6):662-70. PMID: 24385693.

Strel'tsov SA, Kukhanova MK, Gurskiĭ GV, et al. Oxytetracycline binding to E. coli ribosomes. Mol Biol (Mosk). 1975 Nov-Dec;9(6):910-21. PMID: 778591.

" Repr., Xi Not dangerous goods.

LKT O9398 Oxymetazoline Hydrochloride 5 g 121.9 Imidazoline derivative; α1-adrenergic agonist, α2-adrenergic partial agonist. 3-[(4,5-Dihydro-1H-imidazol-2-yl)methyl]-6-(1,1-dimethylethyl)-2,4-dimethylphenyl hydrochloride Afrin; Iliadin; Nafrine; Sinex 2315-02-8 ≥98% 296.84 C16H24N2O HCl CC1=CC(=C(C(=C1CC2=NCCN2)C)O)C(C)(C)C.Cl Ambient Ambient Soluble in water (145 mg/mL), and ethanol (270 mg/mL). "Browning S, Housley D, Richards R, et al. The effects of oxymetazoline on lysozyme secretion from the human nasal mucosa. Acta Otolaryngol. 1997 Nov;117(6):851-5. PMID: 9442826.

Westerveld GJ, Scheeren RA, Dekker I, et al. Anti-oxidant actions of oxymethazoline and xylomethazoline. Eur J Pharmacol. 1995 Sep 15;291(1):27-31. PMID: 8549644.

Chen KS, Bharaj SS, King EC. Induction and relief of nasal congestion in ferrets infected with influenza virus. Int J Exp Pathol. 1995 Feb;76(1):55-64. PMID: 7537523.

" T+ "UN number: 2811     Class: 6.1     Packing Group: I

Proper shipping name: Toxic solid, organic, n.o.s. (Oxymetazoline hydrochloride)"

LKT O9398 Oxymetazoline Hydrochloride 25 g 486.6 Imidazoline derivative; α1-adrenergic agonist, α2-adrenergic partial agonist. 3-[(4,5-Dihydro-1H-imidazol-2-yl)methyl]-6-(1,1-dimethylethyl)-2,4-dimethylphenyl hydrochloride Afrin; Iliadin; Nafrine; Sinex 2315-02-8 ≥98% 296.84 C16H24N2O HCl CC1=CC(=C(C(=C1CC2=NCCN2)C)O)C(C)(C)C.Cl Ambient Ambient Soluble in water (145 mg/mL), and ethanol (270 mg/mL). "Browning S, Housley D, Richards R, et al. The effects of oxymetazoline on lysozyme secretion from the human nasal mucosa. Acta Otolaryngol. 1997 Nov;117(6):851-5. PMID: 9442826.

Westerveld GJ, Scheeren RA, Dekker I, et al. Anti-oxidant actions of oxymethazoline and xylomethazoline. Eur J Pharmacol. 1995 Sep 15;291(1):27-31. PMID: 8549644.

Chen KS, Bharaj SS, King EC. Induction and relief of nasal congestion in ferrets infected with influenza virus. Int J Exp Pathol. 1995 Feb;76(1):55-64. PMID: 7537523.

" T+ "UN number: 2811     Class: 6.1     Packing Group: I

Proper shipping name: Toxic solid, organic, n.o.s. (Oxymetazoline hydrochloride)"

LKT O9497 Oxytocin 5 mg 201.8 Endogenous neuropeptide hormone, involved in social recognition and intimacy behavior; OXTR agonist, acid-sensing ion channel blocker. "L-Cysteinyl-L-tyrosyl-L-isoleucyl-L-glutaminyl-L-

asparaginyl-L-cysteinyl-L-prolyl-L-leucylglycinamide cyclic 

(1-6)-disulfide" Ocytocin; Interocine-S; Perlacton; Pitocin; Syntocinon; Orasthin; Oxystin; Partocon. 50-56-6 ≥95% 1007.2 C43H66N12O12S2 CCC(C)C1C(=O)NC(C(=O)NC(C(=O)NC(CSSCC(C(=O)NC(C(=O)N1)CC2=CC=C(C=C2)O)N)C(=O)N3CCCC3C(=O)NC(CC(C)C)C(=O)NCC(=O)N)CC(=O)N)CCC(=O)N Ambient -20°C Soluble in water, 1-butanol or 2-butanol. "Breuil V, Panaia-Ferrari P, Fontas E, et al. Oxytocin, a new determinant of bone mineral density in post-menopausal women: analysis of the OPUS cohort. J Clin Endocrinol Metab. 2014 Apr;99(4):E634-41. PMID: 24446658.

Yuen KW, Garner JP, Carson DS, et al. Plasma oxytocin concentrations are lower in depressed vs. healthy control women and are independent of cortisol. J Psychiatr Res. 2014 Apr;51:30-6. PMID: 24405552.

Qiu F, Qiu CY, Cai H, et al. Oxytocin inhibits the activity of acid-sensing ion channels through the vasopressin-1a receptor in primary sensory neurons. Br J Pharmacol. 2014 Feb 15. [Epub ahead of print]. PMID: 24641084.

Evans SL, Dal Monte O, Noble P, et al. Intranasal oxytocin effects on social cognition: A critique. Brain Res. 2013 Nov 14. [Epub ahead of print]. PMID: 24239931.

" Xi "UN number: 2811     Class: 6.1     Packing Group: II

Proper shipping name: Toxic solid, organic, n.o.s. (Oxytocin)"

LKT O9497 Oxytocin 25 mg 777 Endogenous neuropeptide hormone, involved in social recognition and intimacy behavior; OXTR agonist, acid-sensing ion channel blocker. "L-Cysteinyl-L-tyrosyl-L-isoleucyl-L-glutaminyl-L-

asparaginyl-L-cysteinyl-L-prolyl-L-leucylglycinamide cyclic 

(1-6)-disulfide" Ocytocin; Interocine-S; Perlacton; Pitocin; Syntocinon; Orasthin; Oxystin; Partocon. 50-56-6 ≥95% 1007.2 C43H66N12O12S2 CCC(C)C1C(=O)NC(C(=O)NC(C(=O)NC(CSSCC(C(=O)NC(C(=O)N1)CC2=CC=C(C=C2)O)N)C(=O)N3CCCC3C(=O)NC(CC(C)C)C(=O)NCC(=O)N)CC(=O)N)CCC(=O)N Ambient -20°C Soluble in water, 1-butanol or 2-butanol. "Breuil V, Panaia-Ferrari P, Fontas E, et al. Oxytocin, a new determinant of bone mineral density in post-menopausal women: analysis of the OPUS cohort. J Clin Endocrinol Metab. 2014 Apr;99(4):E634-41. PMID: 24446658.

Yuen KW, Garner JP, Carson DS, et al. Plasma oxytocin concentrations are lower in depressed vs. healthy control women and are independent of cortisol. J Psychiatr Res. 2014 Apr;51:30-6. PMID: 24405552.

Qiu F, Qiu CY, Cai H, et al. Oxytocin inhibits the activity of acid-sensing ion channels through the vasopressin-1a receptor in primary sensory neurons. Br J Pharmacol. 2014 Feb 15. [Epub ahead of print]. PMID: 24641084.

Evans SL, Dal Monte O, Noble P, et al. Intranasal oxytocin effects on social cognition: A critique. Brain Res. 2013 Nov 14. [Epub ahead of print]. PMID: 24239931.

" Xi "UN number: 2811     Class: 6.1     Packing Group: II

Proper shipping name: Toxic solid, organic, n.o.s. (Oxytocin)"

LKT O9497 Oxytocin 100 mg 2625.3 Endogenous neuropeptide hormone, involved in social recognition and intimacy behavior; OXTR agonist, acid-sensing ion channel blocker. "L-Cysteinyl-L-tyrosyl-L-isoleucyl-L-glutaminyl-L-

asparaginyl-L-cysteinyl-L-prolyl-L-leucylglycinamide cyclic 

(1-6)-disulfide" Ocytocin; Interocine-S; Perlacton; Pitocin; Syntocinon; Orasthin; Oxystin; Partocon. 50-56-6 ≥95% 1007.2 C43H66N12O12S2 CCC(C)C1C(=O)NC(C(=O)NC(C(=O)NC(CSSCC(C(=O)NC(C(=O)N1)CC2=CC=C(C=C2)O)N)C(=O)N3CCCC3C(=O)NC(CC(C)C)C(=O)NCC(=O)N)CC(=O)N)CCC(=O)N Ambient -20°C Soluble in water, 1-butanol or 2-butanol. "Breuil V, Panaia-Ferrari P, Fontas E, et al. Oxytocin, a new determinant of bone mineral density in post-menopausal women: analysis of the OPUS cohort. J Clin Endocrinol Metab. 2014 Apr;99(4):E634-41. PMID: 24446658.

Yuen KW, Garner JP, Carson DS, et al. Plasma oxytocin concentrations are lower in depressed vs. healthy control women and are independent of cortisol. J Psychiatr Res. 2014 Apr;51:30-6. PMID: 24405552.

Qiu F, Qiu CY, Cai H, et al. Oxytocin inhibits the activity of acid-sensing ion channels through the vasopressin-1a receptor in primary sensory neurons. Br J Pharmacol. 2014 Feb 15. [Epub ahead of print]. PMID: 24641084.

Evans SL, Dal Monte O, Noble P, et al. Intranasal oxytocin effects on social cognition: A critique. Brain Res. 2013 Nov 14. [Epub ahead of print]. PMID: 24239931.

" Xi "UN number: 2811     Class: 6.1     Packing Group: II

Proper shipping name: Toxic solid, organic, n.o.s. (Oxytocin)"

LKT O9497 Oxytocin 1 g 7258.4 Endogenous neuropeptide hormone, involved in social recognition and intimacy behavior; OXTR agonist, acid-sensing ion channel blocker. "L-Cysteinyl-L-tyrosyl-L-isoleucyl-L-glutaminyl-L-

asparaginyl-L-cysteinyl-L-prolyl-L-leucylglycinamide cyclic 

(1-6)-disulfide" Ocytocin; Interocine-S; Perlacton; Pitocin; Syntocinon; Orasthin; Oxystin; Partocon. 50-56-6 ≥95% 1007.2 C43H66N12O12S2 CCC(C)C1C(=O)NC(C(=O)NC(C(=O)NC(CSSCC(C(=O)NC(C(=O)N1)CC2=CC=C(C=C2)O)N)C(=O)N3CCCC3C(=O)NC(CC(C)C)C(=O)NCC(=O)N)CC(=O)N)CCC(=O)N Ambient -20°C Soluble in water, 1-butanol or 2-butanol. "Breuil V, Panaia-Ferrari P, Fontas E, et al. Oxytocin, a new determinant of bone mineral density in post-menopausal women: analysis of the OPUS cohort. J Clin Endocrinol Metab. 2014 Apr;99(4):E634-41. PMID: 24446658.

Yuen KW, Garner JP, Carson DS, et al. Plasma oxytocin concentrations are lower in depressed vs. healthy control women and are independent of cortisol. J Psychiatr Res. 2014 Apr;51:30-6. PMID: 24405552.

Qiu F, Qiu CY, Cai H, et al. Oxytocin inhibits the activity of acid-sensing ion channels through the vasopressin-1a receptor in primary sensory neurons. Br J Pharmacol. 2014 Feb 15. [Epub ahead of print]. PMID: 24641084.

Evans SL, Dal Monte O, Noble P, et al. Intranasal oxytocin effects on social cognition: A critique. Brain Res. 2013 Nov 14. [Epub ahead of print]. PMID: 24239931.

" Xi "UN number: 2811     Class: 6.1     Packing Group: II

Proper shipping name: Toxic solid, organic, n.o.s. (Oxytocin)"

LKT O9596 Oxybutynin Hydrochloride 250 mg 46.1 mAChR antagonist. 4-diethylaminobut-2-ynyl 2-cyclohexyl-2-hydroxy-2-phenylacetate 1508-65-2 ≥98% 393.95 C22H31NO3HCl CCN(CC)CC#CCOC(=O)C(C1CCCCC1)(C2=CC=CC=C2)O.Cl Ambient Ambient "De Laet K, De Wachter S, Wyndaele JJ. Systemic oxybutynin decreases afferent activity of the pelvic nerve of the rat: new insights into the working mechanism of antimuscarinics. Neurourol Urodyn. 2006;25(2):156-61. PMID: 16372316.

Park JM, Bauer SB, Freeman MR, et al. Oxybutynin chloride inhibits proliferation and suppresses gene expression in bladder smooth muscle cells. J Urol. 1999 Sep;162(3 Pt 2):1110-4. PMID: 10458442.

" Xn Not dangerous goods.

LKT O9596 Oxybutynin Hydrochloride 1 g 115.3 mAChR antagonist. 4-diethylaminobut-2-ynyl 2-cyclohexyl-2-hydroxy-2-phenylacetate 1508-65-2 ≥98% 393.95 C22H31NO3HCl CCN(CC)CC#CCOC(=O)C(C1CCCCC1)(C2=CC=CC=C2)O.Cl Ambient Ambient "De Laet K, De Wachter S, Wyndaele JJ. Systemic oxybutynin decreases afferent activity of the pelvic nerve of the rat: new insights into the working mechanism of antimuscarinics. Neurourol Urodyn. 2006;25(2):156-61. PMID: 16372316.

Park JM, Bauer SB, Freeman MR, et al. Oxybutynin chloride inhibits proliferation and suppresses gene expression in bladder smooth muscle cells. J Urol. 1999 Sep;162(3 Pt 2):1110-4. PMID: 10458442.

" Xn Not dangerous goods.

LKT O9702 Ozagrel Hydrochloride 10 mg 67.9 TxA2 synthase inhibitor. "3-[4-(1H-imidazol-1-ylmethyl)phenyl]-2E-propenoic acid; 

OKY-046 " 82571-53-7  ≥98% 264.71 C13H12N2O2  HCl C1=CC(=CC=C1CN2C=CN=C2)C=CC(=O)O Ambient Ambient "Sathler PC, Santana M, Lourenço AL, et al. Human thromboxane synthase: comparative modeling and docking evaluation with the competitive inhibitors Dazoxiben and Ozagrel. J Enzyme Inhib Med Chem. 2013 Aug 5. Epub ahead of print. PMID: 23914925.

Tomishima Y, Ishitsuka Y, Matsunaga N, et al. Ozagrel hydrochloride, a selective thromboxane A2 synthase inhibitor, alleviates liver injury induced by acetaminophen overdose in mice. BMC Gastroenterol. 2013 Jan 30;13:21. PMID: 23363429.

Lee S, Morgan GA, Harris NR. Ozagrel reverses streptozotocin-induced constriction of arterioles in rat retina. Microvasc Res. 2008 Nov;76(3):217-23. PMID: 18718478.

Fujimura M, Ogawa H, Saito M, et al. Inhibitory effect of inhalation of a thromboxane synthetase inhibitor on bronchoconstriction induced by aerosolized leukotriene C4 and thromboxane A2 analogue in anesthetized guinea pigs. Allergy. 1991 Oct;46(7):534-9. PMID: 1796779.

Hoshino M, Fukushima Y. Effect of OKY-046 (thromboxane A2 synthetase inhibitor) on exercise-induced asthma. J Asthma. 1991;28(1):19-29. PMID: 1849133.

Nambu F, Murakata S, Shiraji T, et al. OKY-046 inhibits anaphylactic bronchoconstriction and reduces histamine level in bronchoalveolar lavage fluid in sensitized guinea pigs. Prostaglandins. 1990 Jun;39(6):623-37. PMID: 1695383.

Tomoda H. Development of an experimental model of acute myocardial infarction and the effects of a thromboxane synthetase inhibitor (OKY-046). Am Heart J. 1986 Oct;112(4):696-704. PMID: 3532743.

" Not dangerous goods.

LKT O9702 Ozagrel Hydrochloride 25 mg 136 TxA2 synthase inhibitor. "3-[4-(1H-imidazol-1-ylmethyl)phenyl]-2E-propenoic acid; 

OKY-046 " 82571-53-7  ≥98% 264.71 C13H12N2O2  HCl C1=CC(=CC=C1CN2C=CN=C2)C=CC(=O)O Ambient Ambient "Sathler PC, Santana M, Lourenço AL, et al. Human thromboxane synthase: comparative modeling and docking evaluation with the competitive inhibitors Dazoxiben and Ozagrel. J Enzyme Inhib Med Chem. 2013 Aug 5. Epub ahead of print. PMID: 23914925.

Tomishima Y, Ishitsuka Y, Matsunaga N, et al. Ozagrel hydrochloride, a selective thromboxane A2 synthase inhibitor, alleviates liver injury induced by acetaminophen overdose in mice. BMC Gastroenterol. 2013 Jan 30;13:21. PMID: 23363429.

Lee S, Morgan GA, Harris NR. Ozagrel reverses streptozotocin-induced constriction of arterioles in rat retina. Microvasc Res. 2008 Nov;76(3):217-23. PMID: 18718478.

Fujimura M, Ogawa H, Saito M, et al. Inhibitory effect of inhalation of a thromboxane synthetase inhibitor on bronchoconstriction induced by aerosolized leukotriene C4 and thromboxane A2 analogue in anesthetized guinea pigs. Allergy. 1991 Oct;46(7):534-9. PMID: 1796779.

Hoshino M, Fukushima Y. Effect of OKY-046 (thromboxane A2 synthetase inhibitor) on exercise-induced asthma. J Asthma. 1991;28(1):19-29. PMID: 1849133.

Nambu F, Murakata S, Shiraji T, et al. OKY-046 inhibits anaphylactic bronchoconstriction and reduces histamine level in bronchoalveolar lavage fluid in sensitized guinea pigs. Prostaglandins. 1990 Jun;39(6):623-37. PMID: 1695383.

Tomoda H. Development of an experimental model of acute myocardial infarction and the effects of a thromboxane synthetase inhibitor (OKY-046). Am Heart J. 1986 Oct;112(4):696-704. PMID: 3532743.

" Not dangerous goods.

LKT O9702 Ozagrel Hydrochloride 100 mg 434.9 TxA2 synthase inhibitor. "3-[4-(1H-imidazol-1-ylmethyl)phenyl]-2E-propenoic acid; 

OKY-046 " 82571-53-7  ≥98% 264.71 C13H12N2O2  HCl C1=CC(=CC=C1CN2C=CN=C2)C=CC(=O)O Ambient Ambient "Sathler PC, Santana M, Lourenço AL, et al. Human thromboxane synthase: comparative modeling and docking evaluation with the competitive inhibitors Dazoxiben and Ozagrel. J Enzyme Inhib Med Chem. 2013 Aug 5. Epub ahead of print. PMID: 23914925.

Tomishima Y, Ishitsuka Y, Matsunaga N, et al. Ozagrel hydrochloride, a selective thromboxane A2 synthase inhibitor, alleviates liver injury induced by acetaminophen overdose in mice. BMC Gastroenterol. 2013 Jan 30;13:21. PMID: 23363429.

Lee S, Morgan GA, Harris NR. Ozagrel reverses streptozotocin-induced constriction of arterioles in rat retina. Microvasc Res. 2008 Nov;76(3):217-23. PMID: 18718478.

Fujimura M, Ogawa H, Saito M, et al. Inhibitory effect of inhalation of a thromboxane synthetase inhibitor on bronchoconstriction induced by aerosolized leukotriene C4 and thromboxane A2 analogue in anesthetized guinea pigs. Allergy. 1991 Oct;46(7):534-9. PMID: 1796779.

Hoshino M, Fukushima Y. Effect of OKY-046 (thromboxane A2 synthetase inhibitor) on exercise-induced asthma. J Asthma. 1991;28(1):19-29. PMID: 1849133.

Nambu F, Murakata S, Shiraji T, et al. OKY-046 inhibits anaphylactic bronchoconstriction and reduces histamine level in bronchoalveolar lavage fluid in sensitized guinea pigs. Prostaglandins. 1990 Jun;39(6):623-37. PMID: 1695383.

Tomoda H. Development of an experimental model of acute myocardial infarction and the effects of a thromboxane synthetase inhibitor (OKY-046). Am Heart J. 1986 Oct;112(4):696-704. PMID: 3532743.

" Not dangerous goods.

LKT R8207 β-Rubromycin 1 mg 216 Quinolone; telomerase and HIV-1 reverse transcriptase inhibitor. Spiro(benzo(1,2-b:5,4-c')dipyran-2(3H),2'(3'H)-naphtho(1,2-b)furan)-7-carboxylic acid,4,4',5',9-tetrahydro -6',10-dihydroxy-7',9'-dimethoxy-4',5',9-trioxo-, methyl ester 27267-70-5 ≥98% 536.44 C27H20O12 COC1=CC(=C(C2=C1C(=O)C3=C(C2=O)OC4(C3)CCC5=C(O4)C(=C6C(=C5)C=C(OC6=O)C(=O)OC)O)O)OC Ambient -20°C "Mizushina Y, Takeuchi T, Sugawara F, et al. Anti-cancer targeting telomerase inhibitors: β-rubromycin and oleic acid. Mini Rev Med Chem. 2012 Oct;12(11):1135-43. PMID: 22876944.

Ueno T, Takahashi H, Oda M, et al. Inhibition of human telomerase by rubromycins: implication of spiroketal system of the compounds as an active moiety. Biochemistry. 2000 May 23;39(20):5995-6002. PMID: 10821671.

Goldman ME, Salituro GS, Bowen JA, et al. Inhibition of human immunodeficiency virus-1 reverse transcriptase activity by rubromycins: competitive interaction at the template.primer site. Mol Pharmacol. 1990 Jul;38(1):20-5. PMID: 1695317.

" Not dangerous goods.

LKT R8207 β-Rubromycin 5 mg 837.3 Quinolone; telomerase and HIV-1 reverse transcriptase inhibitor. Spiro(benzo(1,2-b:5,4-c')dipyran-2(3H),2'(3'H)-naphtho(1,2-b)furan)-7-carboxylic acid,4,4',5',9-tetrahydro -6',10-dihydroxy-7',9'-dimethoxy-4',5',9-trioxo-, methyl ester 27267-70-5 ≥98% 536.44 C27H20O12 COC1=CC(=C(C2=C1C(=O)C3=C(C2=O)OC4(C3)CCC5=C(O4)C(=C6C(=C5)C=C(OC6=O)C(=O)OC)O)O)OC Ambient -20°C "Mizushina Y, Takeuchi T, Sugawara F, et al. Anti-cancer targeting telomerase inhibitors: β-rubromycin and oleic acid. Mini Rev Med Chem. 2012 Oct;12(11):1135-43. PMID: 22876944.

Ueno T, Takahashi H, Oda M, et al. Inhibition of human telomerase by rubromycins: implication of spiroketal system of the compounds as an active moiety. Biochemistry. 2000 May 23;39(20):5995-6002. PMID: 10821671.

Goldman ME, Salituro GS, Bowen JA, et al. Inhibition of human immunodeficiency virus-1 reverse transcriptase activity by rubromycins: competitive interaction at the template.primer site. Mol Pharmacol. 1990 Jul;38(1):20-5. PMID: 1695317.

" Not dangerous goods.

LKT R8206 Rubescensin A 25 mg 101.7 Diterpene originally found in Rabdosia. 7,20-epoxy-1,6,7,14-tetrahydroxy-(1α,6β,7α,14R)- kaur-16-en-15-one Oridonin, Isodono, Rubescensine A 28957-04-2 ≥93% 364.43 C20H28O6 CC1(CCC(C23C1C(C(C45C2CCC(C4O)C(=C)C5=O)(OC3)O)O)O)C Store in a cool, dry place. Protect from light. Shelf life is 18 months. Ambient 4°C Zhang Y, Xiao S, Sun L, et al. Rapid screening of bioactive compounds from natural products by integrating 5-channel parallel chromatography coupled with on-line mass spectrometry and microplate based assays. Anal Chim Acta. 2013 May 13;777:49-56. PMID: 23622964. Xn Not dangerous goods.

LKT R8206 Rubescensin A 100 mg 305 Diterpene originally found in Rabdosia. 7,20-epoxy-1,6,7,14-tetrahydroxy-(1α,6β,7α,14R)- kaur-16-en-15-one Oridonin, Isodono, Rubescensine A 28957-04-2 ≥93% 364.43 C20H28O6 CC1(CCC(C23C1C(C(C45C2CCC(C4O)C(=C)C5=O)(OC3)O)O)O)C Store in a cool, dry place. Protect from light. Shelf life is 18 months. Ambient 4°C Zhang Y, Xiao S, Sun L, et al. Rapid screening of bioactive compounds from natural products by integrating 5-channel parallel chromatography coupled with on-line mass spectrometry and microplate based assays. Anal Chim Acta. 2013 May 13;777:49-56. PMID: 23622964. Xn Not dangerous goods.

LKT R8206 Rubescensin A 500 mg 1016.6 Diterpene originally found in Rabdosia. 7,20-epoxy-1,6,7,14-tetrahydroxy-(1α,6β,7α,14R)- kaur-16-en-15-one Oridonin, Isodono, Rubescensine A 28957-04-2 ≥93% 364.43 C20H28O6 CC1(CCC(C23C1C(C(C45C2CCC(C4O)C(=C)C5=O)(OC3)O)O)O)C Store in a cool, dry place. Protect from light. Shelf life is 18 months. Ambient 4°C Zhang Y, Xiao S, Sun L, et al. Rapid screening of bioactive compounds from natural products by integrating 5-channel parallel chromatography coupled with on-line mass spectrometry and microplate based assays. Anal Chim Acta. 2013 May 13;777:49-56. PMID: 23622964. Xn Not dangerous goods.

LKT P0256 Pantoprazole Sodium Sesquihydrate 1 g 57.8 H+/K+ ATPase and ROCK-2 inhibitor. 5-(Difluoromethoxy)-2-[[(3,4-dimethoxy-2-pyridinyl)- methyl]sulfinyl]-1H-benzimidazole sodium salt Eupantol; Pantozol; Protonix; Somac 138786-67-1 ≥98% 432.37 C16H14F2N3NaO4S 3/2 H2O COC1=C(C(=NC=C1)CS(=O)C2=NC3=C([N-]2)C=CC(=C3)OC(F)F)OC.[Na+] Ambient Ambient Soluble in water or ethanol. "Welsh C, Kasirer MY, Pan J, et al. Pantoprazole decreases gastroesophageal muscle tone in newborn rats via rho-kinase inhibition. Am J Physiol Gastrointest Liver Physiol. 2014 Apr 3. [Epub ahead of print]. PMID: 24699328.

Shea TA, Burburan PJ, Matubia VN, et al. Identification of proton-pump inhibitor drugs that inhibit Trichomonas vaginalis uridine nucleoside ribohydrolase. Bioorg Med Chem Lett. 2014 Feb 15;24(4):1080-4. PMID: 24468412.

Ward RM, Kearns GL. Proton pump inhibitors in pediatrics : mechanism of action, pharmacokinetics, pharmacogenetics, and pharmacodynamics. Paediatr Drugs. 2013 Apr;15(2):119-31. PMID: 23512128.

Vishvakarma NK, Singh SM. Immunopotentiating effect of proton pump inhibitor pantoprazole in a lymphoma-bearing murine host: Implication in antitumor activation of tumor-associated macrophages. Immunol Lett. 2010 Nov 30;134(1):83-92. PMID: 20837061.

" Xi, Xn Not dangerous goods.

LKT P0256 Pantoprazole Sodium Sesquihydrate 5 g 196.8 H+/K+ ATPase and ROCK-2 inhibitor. 5-(Difluoromethoxy)-2-[[(3,4-dimethoxy-2-pyridinyl)- methyl]sulfinyl]-1H-benzimidazole sodium salt Eupantol; Pantozol; Protonix; Somac 138786-67-1 ≥98% 432.37 C16H14F2N3NaO4S 3/2 H2O COC1=C(C(=NC=C1)CS(=O)C2=NC3=C([N-]2)C=CC(=C3)OC(F)F)OC.[Na+] Ambient Ambient Soluble in water or ethanol. "Welsh C, Kasirer MY, Pan J, et al. Pantoprazole decreases gastroesophageal muscle tone in newborn rats via rho-kinase inhibition. Am J Physiol Gastrointest Liver Physiol. 2014 Apr 3. [Epub ahead of print]. PMID: 24699328.

Shea TA, Burburan PJ, Matubia VN, et al. Identification of proton-pump inhibitor drugs that inhibit Trichomonas vaginalis uridine nucleoside ribohydrolase. Bioorg Med Chem Lett. 2014 Feb 15;24(4):1080-4. PMID: 24468412.

Ward RM, Kearns GL. Proton pump inhibitors in pediatrics : mechanism of action, pharmacokinetics, pharmacogenetics, and pharmacodynamics. Paediatr Drugs. 2013 Apr;15(2):119-31. PMID: 23512128.

Vishvakarma NK, Singh SM. Immunopotentiating effect of proton pump inhibitor pantoprazole in a lymphoma-bearing murine host: Implication in antitumor activation of tumor-associated macrophages. Immunol Lett. 2010 Nov 30;134(1):83-92. PMID: 20837061.

" Xi, Xn Not dangerous goods.

LKT P0256 Pantoprazole Sodium Sesquihydrate 25 g 693.2 H+/K+ ATPase and ROCK-2 inhibitor. 5-(Difluoromethoxy)-2-[[(3,4-dimethoxy-2-pyridinyl)- methyl]sulfinyl]-1H-benzimidazole sodium salt Eupantol; Pantozol; Protonix; Somac 138786-67-1 ≥98% 432.37 C16H14F2N3NaO4S 3/2 H2O COC1=C(C(=NC=C1)CS(=O)C2=NC3=C([N-]2)C=CC(=C3)OC(F)F)OC.[Na+] Ambient Ambient Soluble in water or ethanol. "Welsh C, Kasirer MY, Pan J, et al. Pantoprazole decreases gastroesophageal muscle tone in newborn rats via rho-kinase inhibition. Am J Physiol Gastrointest Liver Physiol. 2014 Apr 3. [Epub ahead of print]. PMID: 24699328.

Shea TA, Burburan PJ, Matubia VN, et al. Identification of proton-pump inhibitor drugs that inhibit Trichomonas vaginalis uridine nucleoside ribohydrolase. Bioorg Med Chem Lett. 2014 Feb 15;24(4):1080-4. PMID: 24468412.

Ward RM, Kearns GL. Proton pump inhibitors in pediatrics : mechanism of action, pharmacokinetics, pharmacogenetics, and pharmacodynamics. Paediatr Drugs. 2013 Apr;15(2):119-31. PMID: 23512128.

Vishvakarma NK, Singh SM. Immunopotentiating effect of proton pump inhibitor pantoprazole in a lymphoma-bearing murine host: Implication in antitumor activation of tumor-associated macrophages. Immunol Lett. 2010 Nov 30;134(1):83-92. PMID: 20837061.

" Xi, Xn Not dangerous goods.

LKT P2508 Phenethyl Isothiocyanate 5 g 67.9 ITC found in cruciferous vegetables. 2-Isothiocyanatoethylbenzene Phenylethyl mustard oil 2257-09-2 ≥98% 163.24 C9H9NS C1=CC=C(C=C1)CCN=C=S Ambient -20°C "Insoluble in water. Soluble in ethanol, DMSO.

Density: 1.094g/ml" "Tusskorn O, Senggunprai L, Prawan A, et al Phenethyl isothiocyanate induces calcium mobilization and mitochondrial cell death pathway in cholangiocarcinoma KKU-M214 cells. BMC Cancer. 2013 Dec 5;13(1):571. PMID: 24304591.

Stan SD, Singh SV, Whitcomb DC, et al. Phenethyl Isothiocyanate Inhibits Proliferation and Induces Apoptosis in Pancreatic Cancer Cells In Vitro and in a MIAPaca2 Xenograft Animal Model. Nutr Cancer. 2013 Nov 6. [Epub ahead of print]. PMID: 24195616.

Gupta B, Chiang L, Chae K, et al. Phenethyl isothiocyanate inhibits hypoxia-induced accumulation of HIF-1α and VEGF expression in human glioma cells. Food Chem. 2013 Dec 1;141(3):1841-6. PMID: 23870899.

Thomson SJ, Brown KK, Pullar JM, et al. Phenethyl isothiocyanate triggers apoptosis in Jurkat cells made resistant by the overexpression of Bcl-2. Cancer Res. 2006 Jul 1;66(13):6772-7. PMID: 16818653.

Yu R, Mandlekar S, Harvey KJ, et al. Chemopreventive isothiocyanates induce apoptosis and caspase-3-like protease activity. Cancer Res. 1998 Feb 1;58(3):402-8. PMID: 9458080.

Yu R, Jiao JJ, Duh JL, et al. Phenethyl isothiocyanate, a natural chemopreventive agent, activates c-Jun N-terminal kinase 1. Cancer Res. 1996 Jul 1;56(13):2954-9. PMID: 8674048.

Guo Z, Smith TJ, Wang E, et al. Structure-activity relationships of arylalkyl isothiocyanates for the inhibition of 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone metabolism and the modulation of xenobiotic-metabolizing enzymes in rats and mice. Carcinogenesis. 1993 Jun;14(6):1167-73. PMID: 8508504." Xn "UN number: 2810  Class: 6.1  Packing group:  II

Proper shipping name:  Toxic liquid, organic, n.o.s. (Phenethyl isothiocyanate)  Marine pollutant:  No  Poison inhalation Hazard:  No"

LKT P2508 Phenethyl Isothiocyanate 10 g 129 ITC found in cruciferous vegetables. 2-Isothiocyanatoethylbenzene Phenylethyl mustard oil 2257-09-2 ≥98% 163.24 C9H9NS C1=CC=C(C=C1)CCN=C=S Ambient -20°C "Insoluble in water. Soluble in ethanol, DMSO.

Density: 1.094g/ml" "Tusskorn O, Senggunprai L, Prawan A, et al Phenethyl isothiocyanate induces calcium mobilization and mitochondrial cell death pathway in cholangiocarcinoma KKU-M214 cells. BMC Cancer. 2013 Dec 5;13(1):571. PMID: 24304591.

Stan SD, Singh SV, Whitcomb DC, et al. Phenethyl Isothiocyanate Inhibits Proliferation and Induces Apoptosis in Pancreatic Cancer Cells In Vitro and in a MIAPaca2 Xenograft Animal Model. Nutr Cancer. 2013 Nov 6. [Epub ahead of print]. PMID: 24195616.

Gupta B, Chiang L, Chae K, et al. Phenethyl isothiocyanate inhibits hypoxia-induced accumulation of HIF-1α and VEGF expression in human glioma cells. Food Chem. 2013 Dec 1;141(3):1841-6. PMID: 23870899.

Thomson SJ, Brown KK, Pullar JM, et al. Phenethyl isothiocyanate triggers apoptosis in Jurkat cells made resistant by the overexpression of Bcl-2. Cancer Res. 2006 Jul 1;66(13):6772-7. PMID: 16818653.

Yu R, Mandlekar S, Harvey KJ, et al. Chemopreventive isothiocyanates induce apoptosis and caspase-3-like protease activity. Cancer Res. 1998 Feb 1;58(3):402-8. PMID: 9458080.

Yu R, Jiao JJ, Duh JL, et al. Phenethyl isothiocyanate, a natural chemopreventive agent, activates c-Jun N-terminal kinase 1. Cancer Res. 1996 Jul 1;56(13):2954-9. PMID: 8674048.

Guo Z, Smith TJ, Wang E, et al. Structure-activity relationships of arylalkyl isothiocyanates for the inhibition of 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone metabolism and the modulation of xenobiotic-metabolizing enzymes in rats and mice. Carcinogenesis. 1993 Jun;14(6):1167-73. PMID: 8508504." Xn "UN number: 2810  Class: 6.1  Packing group:  II

Proper shipping name:  Toxic liquid, organic, n.o.s. (Phenethyl isothiocyanate)  Marine pollutant:  No  Poison inhalation Hazard:  No"

LKT P2508 Phenethyl Isothiocyanate 50 g 543.6 ITC found in cruciferous vegetables. 2-Isothiocyanatoethylbenzene Phenylethyl mustard oil 2257-09-2 ≥98% 163.24 C9H9NS C1=CC=C(C=C1)CCN=C=S Ambient -20°C "Insoluble in water. Soluble in ethanol, DMSO.

Density: 1.094g/ml" "Tusskorn O, Senggunprai L, Prawan A, et al Phenethyl isothiocyanate induces calcium mobilization and mitochondrial cell death pathway in cholangiocarcinoma KKU-M214 cells. BMC Cancer. 2013 Dec 5;13(1):571. PMID: 24304591.

Stan SD, Singh SV, Whitcomb DC, et al. Phenethyl Isothiocyanate Inhibits Proliferation and Induces Apoptosis in Pancreatic Cancer Cells In Vitro and in a MIAPaca2 Xenograft Animal Model. Nutr Cancer. 2013 Nov 6. [Epub ahead of print]. PMID: 24195616.

Gupta B, Chiang L, Chae K, et al. Phenethyl isothiocyanate inhibits hypoxia-induced accumulation of HIF-1α and VEGF expression in human glioma cells. Food Chem. 2013 Dec 1;141(3):1841-6. PMID: 23870899.

Thomson SJ, Brown KK, Pullar JM, et al. Phenethyl isothiocyanate triggers apoptosis in Jurkat cells made resistant by the overexpression of Bcl-2. Cancer Res. 2006 Jul 1;66(13):6772-7. PMID: 16818653.

Yu R, Mandlekar S, Harvey KJ, et al. Chemopreventive isothiocyanates induce apoptosis and caspase-3-like protease activity. Cancer Res. 1998 Feb 1;58(3):402-8. PMID: 9458080.

Yu R, Jiao JJ, Duh JL, et al. Phenethyl isothiocyanate, a natural chemopreventive agent, activates c-Jun N-terminal kinase 1. Cancer Res. 1996 Jul 1;56(13):2954-9. PMID: 8674048.

Guo Z, Smith TJ, Wang E, et al. Structure-activity relationships of arylalkyl isothiocyanates for the inhibition of 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone metabolism and the modulation of xenobiotic-metabolizing enzymes in rats and mice. Carcinogenesis. 1993 Jun;14(6):1167-73. PMID: 8508504." Xn "UN number: 2810  Class: 6.1  Packing group:  II

Proper shipping name:  Toxic liquid, organic, n.o.s. (Phenethyl isothiocyanate)  Marine pollutant:  No  Poison inhalation Hazard:  No"

LKT R5661 Ropinirole Hydrochloride 25 mg 83.9 Indoline; D2/3 agonist. 4-[2-(Dipropylamino)-ethyl]-1,3-dihydro-2H-indol-2-one hydrochloride SKF-101468A 91374-20-8 ≥99% 296.84 C16H24N2O HCl CCCN(CCC)CCC1=C2CC(=O)NC2=CC=C1.Cl Ambient 4°C Soluble in water. "Park G, Park YJ, Yang HO, et al. Ropinirole protects against 1-methyl-4-phenyl-1, 2, 3, 6-tetrahydropyridine (MPTP)-induced neurotoxicity in mice via anti-apoptotic mechanism. Pharmacol Biochem Behav. 2013 Mar;104:163-8. PMID: 23369986.

Ferini-Strambi L. Treatment options for restless legs syndrome. Expert Opin Pharmacother. 2009 Mar;10(4):545-54. PMID: 19284359.

Dhir A, Kulkarni SK. Involvement of dopamine (DA)/serotonin (5-HT)/sigma (sigma) receptor modulation in mediating the antidepressant action of ropinirole hydrochloride, a D2/D3 dopamine receptor agonist. Brain Res Bull. 2007 Sep 14;74(1-3):58-65. PMID: 17683790.

" Xn, N Not dangerous goods.

LKT R5661 Ropinirole Hydrochloride 100 mg 178.5 Indoline; D2/3 agonist. 4-[2-(Dipropylamino)-ethyl]-1,3-dihydro-2H-indol-2-one hydrochloride SKF-101468A 91374-20-8 ≥99% 296.84 C16H24N2O HCl CCCN(CCC)CCC1=C2CC(=O)NC2=CC=C1.Cl Ambient 4°C Soluble in water. "Park G, Park YJ, Yang HO, et al. Ropinirole protects against 1-methyl-4-phenyl-1, 2, 3, 6-tetrahydropyridine (MPTP)-induced neurotoxicity in mice via anti-apoptotic mechanism. Pharmacol Biochem Behav. 2013 Mar;104:163-8. PMID: 23369986.

Ferini-Strambi L. Treatment options for restless legs syndrome. Expert Opin Pharmacother. 2009 Mar;10(4):545-54. PMID: 19284359.

Dhir A, Kulkarni SK. Involvement of dopamine (DA)/serotonin (5-HT)/sigma (sigma) receptor modulation in mediating the antidepressant action of ropinirole hydrochloride, a D2/D3 dopamine receptor agonist. Brain Res Bull. 2007 Sep 14;74(1-3):58-65. PMID: 17683790.

" Xn, N Not dangerous goods.

LKT R5661 Ropinirole Hydrochloride 500 mg 735.1 Indoline; D2/3 agonist. 4-[2-(Dipropylamino)-ethyl]-1,3-dihydro-2H-indol-2-one hydrochloride SKF-101468A 91374-20-8 ≥99% 296.84 C16H24N2O HCl CCCN(CCC)CCC1=C2CC(=O)NC2=CC=C1.Cl Ambient 4°C Soluble in water. "Park G, Park YJ, Yang HO, et al. Ropinirole protects against 1-methyl-4-phenyl-1, 2, 3, 6-tetrahydropyridine (MPTP)-induced neurotoxicity in mice via anti-apoptotic mechanism. Pharmacol Biochem Behav. 2013 Mar;104:163-8. PMID: 23369986.

Ferini-Strambi L. Treatment options for restless legs syndrome. Expert Opin Pharmacother. 2009 Mar;10(4):545-54. PMID: 19284359.

Dhir A, Kulkarni SK. Involvement of dopamine (DA)/serotonin (5-HT)/sigma (sigma) receptor modulation in mediating the antidepressant action of ropinirole hydrochloride, a D2/D3 dopamine receptor agonist. Brain Res Bull. 2007 Sep 14;74(1-3):58-65. PMID: 17683790.

" Xn, N Not dangerous goods.

LKT R8179 Rutaecarpine, synthetic 100 mg 127.5 Found in Evodia rutaecarpa; potential cAMP, 3β-HSD, 11β-hydroxylase inhibitor. 8,13-Dihydroindolo[2',3':3,4]pyrido[2,1-b]quinazolin- 5(7H)-one Rutecarpine 84-26-4 ≥98% 287.32 C18H13N3O C1CN2C(=NC3=CC=CC=C3C2=O)C4=C1C5=CC=CC=C5N4 Ambient 4°C Soluble in alcohol, benzene, chloroform and ether. Practically insoluble in water. "Xu Y, Liu Q, Xu Y, et al. Rutaecarpine suppresses atherosclerosis in ApoE-/- mice through up-regulating ABCA1 and SR-BI within RCT. J Lipid Res. 2014 Jun 7. [Epub ahead of print]. PMID: 24908654.

Chen YC, Zeng XY, He Y, et al. Rutaecarpine analogues reduce lipid accumulation in adipocytes via inhibiting adipogenesis/lipogenesis with AMPK activation and UPR suppression. ACS Chem Biol. 2013 Oct 18;8(10):2301-11. PMID: 23962138.

Bao MH, Dai W, Li YJ, et al. Rutaecarpine prevents hypoxia-reoxygenation-induced myocardial cell apoptosis via inhibition of NADPH oxidases. Can J Physiol Pharmacol. 2011 Mar;89(3):177-86. PMID: 21423291.

Kim SJ, Lee SJ, Lee S, et al. Rutecarpine ameliorates bodyweight gain through the inhibition of orexigenic neuropeptides NPY and AgRP in mice. Biochem Biophys Res Commun. 2009 Nov 20;389(3):437-42. PMID: 19732749.

Yu PL, Chao HL, Wang SW, et al. Effects of evodiamine and rutaecarpine on the secretion of corticosterone by zona fasciculata-reticularis cells in male rats. J Cell Biochem. 2009 Oct 1;108(2):469-75. PMID: 19639602.

Sheu JR, Hung WC, Lee YM, et al. Mechanism of inhibition of platelet aggregation by rutaecarpine, an alkaloid isolated from Evodia rutaecarpa. Eur J Pharmacol. 1996 Dec 30;318(2-3):469-75. PMID: 9016940.

" T Not dangerous goods.

LKT R8179 Rutaecarpine, synthetic 250 mg 271.8 Found in Evodia rutaecarpa; potential cAMP, 3β-HSD, 11β-hydroxylase inhibitor. 8,13-Dihydroindolo[2',3':3,4]pyrido[2,1-b]quinazolin- 5(7H)-one Rutecarpine 84-26-4 ≥98% 287.32 C18H13N3O C1CN2C(=NC3=CC=CC=C3C2=O)C4=C1C5=CC=CC=C5N4 Ambient 4°C Soluble in alcohol, benzene, chloroform and ether. Practically insoluble in water. "Xu Y, Liu Q, Xu Y, et al. Rutaecarpine suppresses atherosclerosis in ApoE-/- mice through up-regulating ABCA1 and SR-BI within RCT. J Lipid Res. 2014 Jun 7. [Epub ahead of print]. PMID: 24908654.

Chen YC, Zeng XY, He Y, et al. Rutaecarpine analogues reduce lipid accumulation in adipocytes via inhibiting adipogenesis/lipogenesis with AMPK activation and UPR suppression. ACS Chem Biol. 2013 Oct 18;8(10):2301-11. PMID: 23962138.

Bao MH, Dai W, Li YJ, et al. Rutaecarpine prevents hypoxia-reoxygenation-induced myocardial cell apoptosis via inhibition of NADPH oxidases. Can J Physiol Pharmacol. 2011 Mar;89(3):177-86. PMID: 21423291.

Kim SJ, Lee SJ, Lee S, et al. Rutecarpine ameliorates bodyweight gain through the inhibition of orexigenic neuropeptides NPY and AgRP in mice. Biochem Biophys Res Commun. 2009 Nov 20;389(3):437-42. PMID: 19732749.

Yu PL, Chao HL, Wang SW, et al. Effects of evodiamine and rutaecarpine on the secretion of corticosterone by zona fasciculata-reticularis cells in male rats. J Cell Biochem. 2009 Oct 1;108(2):469-75. PMID: 19639602.

Sheu JR, Hung WC, Lee YM, et al. Mechanism of inhibition of platelet aggregation by rutaecarpine, an alkaloid isolated from Evodia rutaecarpa. Eur J Pharmacol. 1996 Dec 30;318(2-3):469-75. PMID: 9016940.

" T Not dangerous goods.

LKT R8179 Rutaecarpine, synthetic 1 g 797 Found in Evodia rutaecarpa; potential cAMP, 3β-HSD, 11β-hydroxylase inhibitor. 8,13-Dihydroindolo[2',3':3,4]pyrido[2,1-b]quinazolin- 5(7H)-one Rutecarpine 84-26-4 ≥98% 287.32 C18H13N3O C1CN2C(=NC3=CC=CC=C3C2=O)C4=C1C5=CC=CC=C5N4 Ambient 4°C Soluble in alcohol, benzene, chloroform and ether. Practically insoluble in water. "Xu Y, Liu Q, Xu Y, et al. Rutaecarpine suppresses atherosclerosis in ApoE-/- mice through up-regulating ABCA1 and SR-BI within RCT. J Lipid Res. 2014 Jun 7. [Epub ahead of print]. PMID: 24908654.

Chen YC, Zeng XY, He Y, et al. Rutaecarpine analogues reduce lipid accumulation in adipocytes via inhibiting adipogenesis/lipogenesis with AMPK activation and UPR suppression. ACS Chem Biol. 2013 Oct 18;8(10):2301-11. PMID: 23962138.

Bao MH, Dai W, Li YJ, et al. Rutaecarpine prevents hypoxia-reoxygenation-induced myocardial cell apoptosis via inhibition of NADPH oxidases. Can J Physiol Pharmacol. 2011 Mar;89(3):177-86. PMID: 21423291.

Kim SJ, Lee SJ, Lee S, et al. Rutecarpine ameliorates bodyweight gain through the inhibition of orexigenic neuropeptides NPY and AgRP in mice. Biochem Biophys Res Commun. 2009 Nov 20;389(3):437-42. PMID: 19732749.

Yu PL, Chao HL, Wang SW, et al. Effects of evodiamine and rutaecarpine on the secretion of corticosterone by zona fasciculata-reticularis cells in male rats. J Cell Biochem. 2009 Oct 1;108(2):469-75. PMID: 19639602.

Sheu JR, Hung WC, Lee YM, et al. Mechanism of inhibition of platelet aggregation by rutaecarpine, an alkaloid isolated from Evodia rutaecarpa. Eur J Pharmacol. 1996 Dec 30;318(2-3):469-75. PMID: 9016940.

" T Not dangerous goods.

LKT R8178 Rutaecarpine 10 mg 95.1 Indoloquinazoline alkaloid found in Evodia; COX-2 inhibitor. 8,13-Dihydroindolo[2',3':3,4]pyrido[2,1-b]quinazolin- 5(7H)-one Rutecarpine 84-26-4 ≥98% 287.32 C18H13N3O C1CN2C(=NC3=CC=CC=C3C2=O)C4=C1C5=CC=CC=C5N4 Ambient 4°C Soluble in alcohol, benzene, chloroform and ether. Practically insoluble in water. "Xu Y, Liu Q, Xu Y, et al. Rutaecarpine suppresses atherosclerosis in ApoE-/- mice through up-regulating ABCA1 and SR-BI within RCT. J Lipid Res. 2014 Jun 7. [Epub ahead of print]. PMID: 24908654.

Chen YC, Zeng XY, He Y, et al. Rutaecarpine analogues reduce lipid accumulation in adipocytes via inhibiting adipogenesis/lipogenesis with AMPK activation and UPR suppression. ACS Chem Biol. 2013 Oct 18;8(10):2301-11. PMID: 23962138.

Bao MH, Dai W, Li YJ, et al. Rutaecarpine prevents hypoxia-reoxygenation-induced myocardial cell apoptosis via inhibition of NADPH oxidases. Can J Physiol Pharmacol. 2011 Mar;89(3):177-86. PMID: 21423291.

Kim SJ, Lee SJ, Lee S, et al. Rutecarpine ameliorates bodyweight gain through the inhibition of orexigenic neuropeptides NPY and AgRP in mice. Biochem Biophys Res Commun. 2009 Nov 20;389(3):437-42. PMID: 19732749.

Yu PL, Chao HL, Wang SW, et al. Effects of evodiamine and rutaecarpine on the secretion of corticosterone by zona fasciculata-reticularis cells in male rats. J Cell Biochem. 2009 Oct 1;108(2):469-75. PMID: 19639602.

Sheu JR, Hung WC, Lee YM, et al. Mechanism of inhibition of platelet aggregation by rutaecarpine, an alkaloid isolated from Evodia rutaecarpa. Eur J Pharmacol. 1996 Dec 30;318(2-3):469-75. PMID: 9016940." T Not dangerous goods.

LKT R8178 Rutaecarpine 25 mg 231 Indoloquinazoline alkaloid found in Evodia; COX-2 inhibitor. 8,13-Dihydroindolo[2',3':3,4]pyrido[2,1-b]quinazolin- 5(7H)-one Rutecarpine 84-26-4 ≥98% 287.32 C18H13N3O C1CN2C(=NC3=CC=CC=C3C2=O)C4=C1C5=CC=CC=C5N4 Ambient 4°C Soluble in alcohol, benzene, chloroform and ether. Practically insoluble in water. "Xu Y, Liu Q, Xu Y, et al. Rutaecarpine suppresses atherosclerosis in ApoE-/- mice through up-regulating ABCA1 and SR-BI within RCT. J Lipid Res. 2014 Jun 7. [Epub ahead of print]. PMID: 24908654.

Chen YC, Zeng XY, He Y, et al. Rutaecarpine analogues reduce lipid accumulation in adipocytes via inhibiting adipogenesis/lipogenesis with AMPK activation and UPR suppression. ACS Chem Biol. 2013 Oct 18;8(10):2301-11. PMID: 23962138.

Bao MH, Dai W, Li YJ, et al. Rutaecarpine prevents hypoxia-reoxygenation-induced myocardial cell apoptosis via inhibition of NADPH oxidases. Can J Physiol Pharmacol. 2011 Mar;89(3):177-86. PMID: 21423291.

Kim SJ, Lee SJ, Lee S, et al. Rutecarpine ameliorates bodyweight gain through the inhibition of orexigenic neuropeptides NPY and AgRP in mice. Biochem Biophys Res Commun. 2009 Nov 20;389(3):437-42. PMID: 19732749.

Yu PL, Chao HL, Wang SW, et al. Effects of evodiamine and rutaecarpine on the secretion of corticosterone by zona fasciculata-reticularis cells in male rats. J Cell Biochem. 2009 Oct 1;108(2):469-75. PMID: 19639602.

Sheu JR, Hung WC, Lee YM, et al. Mechanism of inhibition of platelet aggregation by rutaecarpine, an alkaloid isolated from Evodia rutaecarpa. Eur J Pharmacol. 1996 Dec 30;318(2-3):469-75. PMID: 9016940." T Not dangerous goods.

LKT R8178 Rutaecarpine 100 mg 625.1 Indoloquinazoline alkaloid found in Evodia; COX-2 inhibitor. 8,13-Dihydroindolo[2',3':3,4]pyrido[2,1-b]quinazolin- 5(7H)-one Rutecarpine 84-26-4 ≥98% 287.32 C18H13N3O C1CN2C(=NC3=CC=CC=C3C2=O)C4=C1C5=CC=CC=C5N4 Ambient 4°C Soluble in alcohol, benzene, chloroform and ether. Practically insoluble in water. "Xu Y, Liu Q, Xu Y, et al. Rutaecarpine suppresses atherosclerosis in ApoE-/- mice through up-regulating ABCA1 and SR-BI within RCT. J Lipid Res. 2014 Jun 7. [Epub ahead of print]. PMID: 24908654.

Chen YC, Zeng XY, He Y, et al. Rutaecarpine analogues reduce lipid accumulation in adipocytes via inhibiting adipogenesis/lipogenesis with AMPK activation and UPR suppression. ACS Chem Biol. 2013 Oct 18;8(10):2301-11. PMID: 23962138.

Bao MH, Dai W, Li YJ, et al. Rutaecarpine prevents hypoxia-reoxygenation-induced myocardial cell apoptosis via inhibition of NADPH oxidases. Can J Physiol Pharmacol. 2011 Mar;89(3):177-86. PMID: 21423291.

Kim SJ, Lee SJ, Lee S, et al. Rutecarpine ameliorates bodyweight gain through the inhibition of orexigenic neuropeptides NPY and AgRP in mice. Biochem Biophys Res Commun. 2009 Nov 20;389(3):437-42. PMID: 19732749.

Yu PL, Chao HL, Wang SW, et al. Effects of evodiamine and rutaecarpine on the secretion of corticosterone by zona fasciculata-reticularis cells in male rats. J Cell Biochem. 2009 Oct 1;108(2):469-75. PMID: 19639602.

Sheu JR, Hung WC, Lee YM, et al. Mechanism of inhibition of platelet aggregation by rutaecarpine, an alkaloid isolated from Evodia rutaecarpa. Eur J Pharmacol. 1996 Dec 30;318(2-3):469-75. PMID: 9016940." T Not dangerous goods.

LKT R8122 Rufloxacin Hydrochloride 25 mg 67.9 Fluoroquinolone; topoisomerase IV and bacterial DNA gyrase inhibitor. 9-Fluro-2,3-dihydro-10-(4-methyl-1-piperazinyl)-7- oxo-7H-pyridol[1,2,3-de]-1,4-benzothiazine-6-carboxylic acid hydrochloride Qari; Monos; Tebraxin 106017-08-7 ≥98% 399.87 C17H18FN3O3S HCl CN1CCN(CC1)C2=C(C=C3C4=C2SCCN4C=C(C3=O)C(=O)O)F.Cl Ambient Ambient "Gu LY, Lin WW, Lu H, et al. Quadruple therapy with medications containing either rufloxacin or furazolidone as a rescue regimen in the treatment of Helicobacter pylori-infected dyspepsia patients: a randomized pilot study. Helicobacter. 2011 Aug;16(4):284-8. PMID: 21762267.

Belvedere A, Boscá F, Catalfo A, et al. Type II guanine oxidation photoinduced by the antibacterial fluoroquinolone Rufloxacin in isolated DNA and in 2'-deoxyguanosine. Chem Res Toxicol. 2002 Sep;15(9):1142-9. PMID: 12230407.

Montanari MP, Prenna M, Mingoia M, et al. In vitro antibacterial activity of trovafloxacin and five other fluoroquinolones. Chemotherapy. 1998 Mar-Apr;44(2):85-93. PMID: 9551237.

" Not dangerous goods.

LKT R8122 Rufloxacin Hydrochloride 100 mg 218.4 Fluoroquinolone; topoisomerase IV and bacterial DNA gyrase inhibitor. 9-Fluro-2,3-dihydro-10-(4-methyl-1-piperazinyl)-7- oxo-7H-pyridol[1,2,3-de]-1,4-benzothiazine-6-carboxylic acid hydrochloride Qari; Monos; Tebraxin 106017-08-7 ≥98% 399.87 C17H18FN3O3S HCl CN1CCN(CC1)C2=C(C=C3C4=C2SCCN4C=C(C3=O)C(=O)O)F.Cl Ambient Ambient "Gu LY, Lin WW, Lu H, et al. Quadruple therapy with medications containing either rufloxacin or furazolidone as a rescue regimen in the treatment of Helicobacter pylori-infected dyspepsia patients: a randomized pilot study. Helicobacter. 2011 Aug;16(4):284-8. PMID: 21762267.

Belvedere A, Boscá F, Catalfo A, et al. Type II guanine oxidation photoinduced by the antibacterial fluoroquinolone Rufloxacin in isolated DNA and in 2'-deoxyguanosine. Chem Res Toxicol. 2002 Sep;15(9):1142-9. PMID: 12230407.

Montanari MP, Prenna M, Mingoia M, et al. In vitro antibacterial activity of trovafloxacin and five other fluoroquinolones. Chemotherapy. 1998 Mar-Apr;44(2):85-93. PMID: 9551237.

" Not dangerous goods.

LKT R8122 Rufloxacin Hydrochloride 500 mg 630.9 Fluoroquinolone; topoisomerase IV and bacterial DNA gyrase inhibitor. 9-Fluro-2,3-dihydro-10-(4-methyl-1-piperazinyl)-7- oxo-7H-pyridol[1,2,3-de]-1,4-benzothiazine-6-carboxylic acid hydrochloride Qari; Monos; Tebraxin 106017-08-7 ≥98% 399.87 C17H18FN3O3S HCl CN1CCN(CC1)C2=C(C=C3C4=C2SCCN4C=C(C3=O)C(=O)O)F.Cl Ambient Ambient "Gu LY, Lin WW, Lu H, et al. Quadruple therapy with medications containing either rufloxacin or furazolidone as a rescue regimen in the treatment of Helicobacter pylori-infected dyspepsia patients: a randomized pilot study. Helicobacter. 2011 Aug;16(4):284-8. PMID: 21762267.

Belvedere A, Boscá F, Catalfo A, et al. Type II guanine oxidation photoinduced by the antibacterial fluoroquinolone Rufloxacin in isolated DNA and in 2'-deoxyguanosine. Chem Res Toxicol. 2002 Sep;15(9):1142-9. PMID: 12230407.

Montanari MP, Prenna M, Mingoia M, et al. In vitro antibacterial activity of trovafloxacin and five other fluoroquinolones. Chemotherapy. 1998 Mar-Apr;44(2):85-93. PMID: 9551237.

" Not dangerous goods.

LKT R8076 Rutin Hydrate 50 g 46.2 Flavonoid glycoside found in fruit, asparagus, buckwheat. 4H-1-Benzopyran-4-one, 3-((6-O-(6-deoxy-α-L- mannopyranosyl)-β-D-glucopyranosyl)oxy)-2-(3,4-dihydroxyphenyl)-5,7-dihydroxy- 3-Rhamnoglucosylquercetin; Globulariacitrin; Phytomelin; Rutin; Tanrutin; Vitamin P1 153-18-4 ≥93% 610.52 C27H30O16 3H2O CC1C(C(C(C(O1)OCC2C(C(C(C(O2)OC3=C(OC4=CC(=CC(=C4C3=O)O)O)C5=CC(=C(C=C5)O)O)O)O)O)O)O)O Ambient Ambient Soluble in DMSO. "Yeh CH, Yang JJ, Yang ML, et al. Rutin decreases lipopolysaccharide-induced acute lung injury via inhibition of oxidative stress and the MAPK-NF-κB pathway. Free Radic Biol Med. 2014 Apr;69:249-57. PMID: 24486341.

Machawal L, Kumar A. Possible involvement of nitric oxide mechanism in the neuroprotective effect of rutin against immobilization stress induced anxiety like behaviour, oxidative damage in mice. Pharmacol Rep. 2014 Feb;66(1):15-21. PMID: 24905301.

 D. Rutin suppresses palmitic acids-triggered inflammation in macrophages and blocks high fat diet-induced obesity and fatty liver in mice. Pharm Res. 2013 Nov;30(11):2940-50. PMID: 23783345.

Kappel VD, Cazarolli LH, Pereira DF, et al. Involvement of GLUT-4 in the stimulatory effect of rutin on glucose uptake in rat soleus muscle. J Pharm Pharmacol. 2013 Aug;65(8):1179-86. PMID: 23837585.

Magalingam KB, Radhakrishnan A, Haleagrahara N. Rutin, a bioflavonoid antioxidant protects rat pheochromocytoma (PC-12) cells against 6-hydroxydopamine (6-OHDA)-induced neurotoxicity. Int J Mol Med. 2013 Jul;32(1):235-40. PMID: 23670213.

Kappel VD, Frederico MJ, Postal BG, et al. The role of calcium in intracellular pathways of rutin in rat pancreatic islets: potential insulin secretagogue effect. Eur J Pharmacol. 2013 Feb 28;702(1-3):264-8. PMID: 23399767.

Javed H, Khan MM, Ahmad A, et al. Rutin prevents cognitive impairments by ameliorating oxidative stress and neuroinflammation in rat model of sporadic dementia of Alzheimer type. Neuroscience. 2012 May 17;210:340-52. PMID: 22441036.

" Xn, Xi Not dangerous goods.

LKT R8076 Rutin Hydrate 100 g 80.4 Flavonoid glycoside found in fruit, asparagus, buckwheat. 4H-1-Benzopyran-4-one, 3-((6-O-(6-deoxy-α-L- mannopyranosyl)-β-D-glucopyranosyl)oxy)-2-(3,4-dihydroxyphenyl)-5,7-dihydroxy- 3-Rhamnoglucosylquercetin; Globulariacitrin; Phytomelin; Rutin; Tanrutin; Vitamin P1 153-18-4 ≥93% 610.52 C27H30O16 3H2O CC1C(C(C(C(O1)OCC2C(C(C(C(O2)OC3=C(OC4=CC(=CC(=C4C3=O)O)O)C5=CC(=C(C=C5)O)O)O)O)O)O)O)O Ambient Ambient Soluble in DMSO. "Yeh CH, Yang JJ, Yang ML, et al. Rutin decreases lipopolysaccharide-induced acute lung injury via inhibition of oxidative stress and the MAPK-NF-κB pathway. Free Radic Biol Med. 2014 Apr;69:249-57. PMID: 24486341.

Machawal L, Kumar A. Possible involvement of nitric oxide mechanism in the neuroprotective effect of rutin against immobilization stress induced anxiety like behaviour, oxidative damage in mice. Pharmacol Rep. 2014 Feb;66(1):15-21. PMID: 24905301.

 D. Rutin suppresses palmitic acids-triggered inflammation in macrophages and blocks high fat diet-induced obesity and fatty liver in mice. Pharm Res. 2013 Nov;30(11):2940-50. PMID: 23783345.

Kappel VD, Cazarolli LH, Pereira DF, et al. Involvement of GLUT-4 in the stimulatory effect of rutin on glucose uptake in rat soleus muscle. J Pharm Pharmacol. 2013 Aug;65(8):1179-86. PMID: 23837585.

Magalingam KB, Radhakrishnan A, Haleagrahara N. Rutin, a bioflavonoid antioxidant protects rat pheochromocytoma (PC-12) cells against 6-hydroxydopamine (6-OHDA)-induced neurotoxicity. Int J Mol Med. 2013 Jul;32(1):235-40. PMID: 23670213.

Kappel VD, Frederico MJ, Postal BG, et al. The role of calcium in intracellular pathways of rutin in rat pancreatic islets: potential insulin secretagogue effect. Eur J Pharmacol. 2013 Feb 28;702(1-3):264-8. PMID: 23399767.

Javed H, Khan MM, Ahmad A, et al. Rutin prevents cognitive impairments by ameliorating oxidative stress and neuroinflammation in rat model of sporadic dementia of Alzheimer type. Neuroscience. 2012 May 17;210:340-52. PMID: 22441036.

" Xn, Xi Not dangerous goods.

LKT R8076 Rutin Hydrate 500 g 301.5 Flavonoid glycoside found in fruit, asparagus, buckwheat. 4H-1-Benzopyran-4-one, 3-((6-O-(6-deoxy-α-L- mannopyranosyl)-β-D-glucopyranosyl)oxy)-2-(3,4-dihydroxyphenyl)-5,7-dihydroxy- 3-Rhamnoglucosylquercetin; Globulariacitrin; Phytomelin; Rutin; Tanrutin; Vitamin P1 153-18-4 ≥93% 610.52 C27H30O16 3H2O CC1C(C(C(C(O1)OCC2C(C(C(C(O2)OC3=C(OC4=CC(=CC(=C4C3=O)O)O)C5=CC(=C(C=C5)O)O)O)O)O)O)O)O Ambient Ambient Soluble in DMSO. "Yeh CH, Yang JJ, Yang ML, et al. Rutin decreases lipopolysaccharide-induced acute lung injury via inhibition of oxidative stress and the MAPK-NF-κB pathway. Free Radic Biol Med. 2014 Apr;69:249-57. PMID: 24486341.

Machawal L, Kumar A. Possible involvement of nitric oxide mechanism in the neuroprotective effect of rutin against immobilization stress induced anxiety like behaviour, oxidative damage in mice. Pharmacol Rep. 2014 Feb;66(1):15-21. PMID: 24905301.

 D. Rutin suppresses palmitic acids-triggered inflammation in macrophages and blocks high fat diet-induced obesity and fatty liver in mice. Pharm Res. 2013 Nov;30(11):2940-50. PMID: 23783345.

Kappel VD, Cazarolli LH, Pereira DF, et al. Involvement of GLUT-4 in the stimulatory effect of rutin on glucose uptake in rat soleus muscle. J Pharm Pharmacol. 2013 Aug;65(8):1179-86. PMID: 23837585.

Magalingam KB, Radhakrishnan A, Haleagrahara N. Rutin, a bioflavonoid antioxidant protects rat pheochromocytoma (PC-12) cells against 6-hydroxydopamine (6-OHDA)-induced neurotoxicity. Int J Mol Med. 2013 Jul;32(1):235-40. PMID: 23670213.

Kappel VD, Frederico MJ, Postal BG, et al. The role of calcium in intracellular pathways of rutin in rat pancreatic islets: potential insulin secretagogue effect. Eur J Pharmacol. 2013 Feb 28;702(1-3):264-8. PMID: 23399767.

Javed H, Khan MM, Ahmad A, et al. Rutin prevents cognitive impairments by ameliorating oxidative stress and neuroinflammation in rat model of sporadic dementia of Alzheimer type. Neuroscience. 2012 May 17;210:340-52. PMID: 22441036.

" Xn, Xi Not dangerous goods.

LKT R6873 RSR 1 mg 60 Peptide, used in design of DNA binding peptides. ≥95% 417.5 C15H31N9O5 Ambient -20°C Alkhader S, Ezra A, Kasparkova J, et al. A metal-free DNA nuclease based on a cyclic peptide scaffold. Bioconjug Chem. 2010 Aug 18;21(8):1425-31. PMID: 20715847.

LKT R6873 RSR 2 mg 101.9 Peptide, used in design of DNA binding peptides. ≥95% 417.5 C15H31N9O5 Ambient -20°C Alkhader S, Ezra A, Kasparkova J, et al. A metal-free DNA nuclease based on a cyclic peptide scaffold. Bioconjug Chem. 2010 Aug 18;21(8):1425-31. PMID: 20715847.

LKT R6873 RSR 5 mg 180 Peptide, used in design of DNA binding peptides. ≥95% 417.5 C15H31N9O5 Ambient -20°C Alkhader S, Ezra A, Kasparkova J, et al. A metal-free DNA nuclease based on a cyclic peptide scaffold. Bioconjug Chem. 2010 Aug 18;21(8):1425-31. PMID: 20715847.

LKT R6871 RR-SRC 5 mg 264.1 Src-derived tyrosine kinase substrate. ≥95% 1519.7 C64H106N22O21 CCC(C)C(C(=O)NC(CCC(=O)O)C(=O)NC(CC(=O)O)C(=O)NC(C)C(=O)NC(CCC(=O)O)C(=O)NC(CC1=CC=C(C=C1)O)C(=O)NC(C)C(=O)NC(C)C(=O)NC(CCCN=C(N)N)C(=O)NCC(=O)O)NC(=O)C(CC(C)C)NC(=O)C(CCCN=C(N)N)NC(=O)C(CCCN=C(N)N)N Ambient -20°C "Hernández-Ramírez VI, Anaya-Ruiz M, Rios A, et al. Entamoeba histolytica: tyrosine kinase activity induced by fibronectin through the beta1-integrin-like molecule. Exp Parasitol. 2000 Jun;95(2):85-95. PMID: 10910709.

Islas-Flores I I, Oropeza C, Hernandez-Sotomayor SM. Protein phosphorylation during coconut zygotic embryo development  Plant Physiol. 1998 Sep;118(1):257-63. PMID: 9733545.

" Not dangerous goods.

LKT R6871 RR-SRC 10 mg 448.9 Src-derived tyrosine kinase substrate. ≥95% 1519.7 C64H106N22O21 CCC(C)C(C(=O)NC(CCC(=O)O)C(=O)NC(CC(=O)O)C(=O)NC(C)C(=O)NC(CCC(=O)O)C(=O)NC(CC1=CC=C(C=C1)O)C(=O)NC(C)C(=O)NC(C)C(=O)NC(CCCN=C(N)N)C(=O)NCC(=O)O)NC(=O)C(CC(C)C)NC(=O)C(CCCN=C(N)N)NC(=O)C(CCCN=C(N)N)N Ambient -20°C "Hernández-Ramírez VI, Anaya-Ruiz M, Rios A, et al. Entamoeba histolytica: tyrosine kinase activity induced by fibronectin through the beta1-integrin-like molecule. Exp Parasitol. 2000 Jun;95(2):85-95. PMID: 10910709.

Islas-Flores I I, Oropeza C, Hernandez-Sotomayor SM. Protein phosphorylation during coconut zygotic embryo development  Plant Physiol. 1998 Sep;118(1):257-63. PMID: 9733545.

" Not dangerous goods.

LKT R6871 RR-SRC 25 mg 792.1 Src-derived tyrosine kinase substrate. ≥95% 1519.7 C64H106N22O21 CCC(C)C(C(=O)NC(CCC(=O)O)C(=O)NC(CC(=O)O)C(=O)NC(C)C(=O)NC(CCC(=O)O)C(=O)NC(CC1=CC=C(C=C1)O)C(=O)NC(C)C(=O)NC(C)C(=O)NC(CCCN=C(N)N)C(=O)NCC(=O)O)NC(=O)C(CC(C)C)NC(=O)C(CCCN=C(N)N)NC(=O)C(CCCN=C(N)N)N Ambient -20°C "Hernández-Ramírez VI, Anaya-Ruiz M, Rios A, et al. Entamoeba histolytica: tyrosine kinase activity induced by fibronectin through the beta1-integrin-like molecule. Exp Parasitol. 2000 Jun;95(2):85-95. PMID: 10910709.

Islas-Flores I I, Oropeza C, Hernandez-Sotomayor SM. Protein phosphorylation during coconut zygotic embryo development  Plant Physiol. 1998 Sep;118(1):257-63. PMID: 9733545.

" Not dangerous goods.

LKT R5992 Roxithromycin 1 g 27.8 Macrolide; protein synthesis inhibitor. Erythromycin 9-[-O-[(2-methoxyethoxy)methyl]- oxime] Rulide; Surlid; Rotramin; Claramid; Overal; Rossitrol 80214-83-1 ≥96% 837.05 C41H76N2O15 CCC1C(C(C(C(=NOCOCCOC)C(CC(C(C(C(C(C(=O)O1)C)OC2CC(C(C(O2)C)O)(C)OC)C)OC3C(C(CC(O3)C)N(C)C)O)(C)O)C)C)O)(C)O Ambient 4°C Soluble in HCl, and NaOH. Slightly soluble in alcohol and water. "Ci X, Chu X, Xu X, et al. Short-term roxithromycin treatment attenuates airway inflammation via MAPK/NF-κB activation in a mouse model of allergic asthma. Inflamm Res. 2012 Jul;61(7):749-58. PMID: 22481373.

Biava M, Porretta GC, Deidda D, et al. New trends in development of antimycobacterial compounds. Infect Disord Drug Targets. 2006 Jun;6(2):159-72. PMID: 16789877.

Urasaki Y, Nori M, Iwata S, et al. Roxithromycin specifically inhibits development of collagen induced arthritis and production of proinflammatory cytokines by human T cells and macrophages. J Rheumatol. 2005 Sep;32(9):1765-74. PMID: 16142877.

Berman M, Hasdai D, Raanani E, et al. Ex-vivo effect of roxithromycin on human and rat arterial vasoactivity. Interact Cardiovasc Thorac Surg. 2005 Jun;4(3):232-7. PMID: 17670399.

" Xn Not dangerous goods.

LKT R5992 Roxithromycin 5 g 92.5 Macrolide; protein synthesis inhibitor. Erythromycin 9-[-O-[(2-methoxyethoxy)methyl]- oxime] Rulide; Surlid; Rotramin; Claramid; Overal; Rossitrol 80214-83-1 ≥96% 837.05 C41H76N2O15 CCC1C(C(C(C(=NOCOCCOC)C(CC(C(C(C(C(C(=O)O1)C)OC2CC(C(C(O2)C)O)(C)OC)C)OC3C(C(CC(O3)C)N(C)C)O)(C)O)C)C)O)(C)O Ambient 4°C Soluble in HCl, and NaOH. Slightly soluble in alcohol and water. "Ci X, Chu X, Xu X, et al. Short-term roxithromycin treatment attenuates airway inflammation via MAPK/NF-κB activation in a mouse model of allergic asthma. Inflamm Res. 2012 Jul;61(7):749-58. PMID: 22481373.

Biava M, Porretta GC, Deidda D, et al. New trends in development of antimycobacterial compounds. Infect Disord Drug Targets. 2006 Jun;6(2):159-72. PMID: 16789877.

Urasaki Y, Nori M, Iwata S, et al. Roxithromycin specifically inhibits development of collagen induced arthritis and production of proinflammatory cytokines by human T cells and macrophages. J Rheumatol. 2005 Sep;32(9):1765-74. PMID: 16142877.

Berman M, Hasdai D, Raanani E, et al. Ex-vivo effect of roxithromycin on human and rat arterial vasoactivity. Interact Cardiovasc Thorac Surg. 2005 Jun;4(3):232-7. PMID: 17670399.

" Xn Not dangerous goods.

LKT R5992 Roxithromycin 10 g 134.1 Macrolide; protein synthesis inhibitor. Erythromycin 9-[-O-[(2-methoxyethoxy)methyl]- oxime] Rulide; Surlid; Rotramin; Claramid; Overal; Rossitrol 80214-83-1 ≥96% 837.05 C41H76N2O15 CCC1C(C(C(C(=NOCOCCOC)C(CC(C(C(C(C(C(=O)O1)C)OC2CC(C(C(O2)C)O)(C)OC)C)OC3C(C(CC(O3)C)N(C)C)O)(C)O)C)C)O)(C)O Ambient 4°C Soluble in HCl, and NaOH. Slightly soluble in alcohol and water. "Ci X, Chu X, Xu X, et al. Short-term roxithromycin treatment attenuates airway inflammation via MAPK/NF-κB activation in a mouse model of allergic asthma. Inflamm Res. 2012 Jul;61(7):749-58. PMID: 22481373.

Biava M, Porretta GC, Deidda D, et al. New trends in development of antimycobacterial compounds. Infect Disord Drug Targets. 2006 Jun;6(2):159-72. PMID: 16789877.

Urasaki Y, Nori M, Iwata S, et al. Roxithromycin specifically inhibits development of collagen induced arthritis and production of proinflammatory cytokines by human T cells and macrophages. J Rheumatol. 2005 Sep;32(9):1765-74. PMID: 16142877.

Berman M, Hasdai D, Raanani E, et al. Ex-vivo effect of roxithromycin on human and rat arterial vasoactivity. Interact Cardiovasc Thorac Surg. 2005 Jun;4(3):232-7. PMID: 17670399.

" Xn Not dangerous goods.

LKT R5974 Rosuvastatin Calcium 25 mg 112.5 Statin; HMG-CoA reductase inhibitor, potential NADPH oxidase and PKC inhibitor. "(S-((R*,S*-(E)))- 7-(4-(4-fluorophenyl)-6-(1-methylethyl)-2-

(methyl(methylsulfonyl) amino)-5-pyrimidinyl)-3,5-dihydroxy-

6-heptenoic acid, calcium salt (2:1) " 147098-20-2 ≥98% 1001.14 2(C22H28FN3O6S) Ca2+ CC(C)C1=NC(=NC(=C1C=CC(CC(CC(=O)[O-])O)O)C2=CC=C(C=C2)F)N(C)S(=O)(=O)C.CC(C)C1=NC(=NC(=C1C=CC(CC(CC(=O)[O-])O)O)C2=CC=C(C=C2)F)N(C)S(=O)(=O)C.[Ca+2] Ambient Ambient Slightly soluble in water, marginally soluble in ethanol,soluble in DMSO(100mg/mL), DMF "Li Y, Wang Q, Zhou J, et al. Rosuvastatin attenuates atherosclerosis in rats via activation of scavenger receptor class B type I. Eur J Pharmacol. 2013 Dec 10;723C:23-28. [Epub ahead of print]. PMID: 24333476.

Luo B, Li B, Wang W, et al. Rosuvastatin Alleviates Diabetic Cardiomyopathy by Inhibiting NLRP3 Inflammasome and MAPK Pathways in a Type 2 Diabetes Rat Model. Cardiovasc Drugs Ther. 2013 Nov 20. [Epub ahead of print]. PMID: 24254031.

Gan J, Li P, Wang Z, et al. Rosuvastatin suppresses platelet-derived growth factor-BB-induced vascular smooth muscle cell proliferation and migration via the MAPK signaling pathway. Exp Ther Med. 2013 Oct;6(4):899-903. PMID: 24137286.

Hu X, Sun A, Xie X, et al. Rosuvastatin changes cytokine expressions in ischemic territory and preserves heart function after acute myocardial infarction in rats. J Cardiovasc Pharmacol Ther. 2013 Mar;18(2):162-76. PMID: 23139358.

Pignatelli P, Carnevale R, Di Santo S, et al. Rosuvastatin reduces platelet recruitment by inhibiting NADPH oxidase activation. Biochem Pharmacol. 2012 Dec 15;84(12):1635-42. PMID: 23022230.

Laumen H, Skurk T, Hauner H. The HMG-CoA reductase inhibitor rosuvastatin inhibits plasminogen activator inhibitor-1 expression and secretion in human adipocytes. Atherosclerosis. 2008 Feb;196(2):565-73. PMID: 17692320.

Holdgate GA, Ward WH, McTaggart F. Molecular mechanism for inhibition of 3-hydroxy-3-methylglutaryl CoA (HMG-CoA) reductase by rosuvastatin. Biochem Soc Trans. 2003 Jun;31(Pt 3):528-31. PMID: 12773150.

Izumi S, Nozaki Y, Maeda K, et al. Investigation of the impact of substrate selection on in vitro organic anion transporting polypeptide 1B1 inhibition profiles for the prediction of drug-drug interactions. Drug Metab Dispos. 2015 Feb;43(2):235-247. PMID: 25414411.

" Not dangerous goods.

LKT R5974 Rosuvastatin Calcium 100 mg 375.1 Statin; HMG-CoA reductase inhibitor, potential NADPH oxidase and PKC inhibitor. "(S-((R*,S*-(E)))- 7-(4-(4-fluorophenyl)-6-(1-methylethyl)-2-

(methyl(methylsulfonyl) amino)-5-pyrimidinyl)-3,5-dihydroxy-

6-heptenoic acid, calcium salt (2:1) " 147098-20-2 ≥98% 1001.14 2(C22H28FN3O6S) Ca2+ CC(C)C1=NC(=NC(=C1C=CC(CC(CC(=O)[O-])O)O)C2=CC=C(C=C2)F)N(C)S(=O)(=O)C.CC(C)C1=NC(=NC(=C1C=CC(CC(CC(=O)[O-])O)O)C2=CC=C(C=C2)F)N(C)S(=O)(=O)C.[Ca+2] Ambient Ambient Slightly soluble in water, marginally soluble in ethanol,soluble in DMSO(100mg/mL), DMF "Li Y, Wang Q, Zhou J, et al. Rosuvastatin attenuates atherosclerosis in rats via activation of scavenger receptor class B type I. Eur J Pharmacol. 2013 Dec 10;723C:23-28. [Epub ahead of print]. PMID: 24333476.

Luo B, Li B, Wang W, et al. Rosuvastatin Alleviates Diabetic Cardiomyopathy by Inhibiting NLRP3 Inflammasome and MAPK Pathways in a Type 2 Diabetes Rat Model. Cardiovasc Drugs Ther. 2013 Nov 20. [Epub ahead of print]. PMID: 24254031.

Gan J, Li P, Wang Z, et al. Rosuvastatin suppresses platelet-derived growth factor-BB-induced vascular smooth muscle cell proliferation and migration via the MAPK signaling pathway. Exp Ther Med. 2013 Oct;6(4):899-903. PMID: 24137286.

Hu X, Sun A, Xie X, et al. Rosuvastatin changes cytokine expressions in ischemic territory and preserves heart function after acute myocardial infarction in rats. J Cardiovasc Pharmacol Ther. 2013 Mar;18(2):162-76. PMID: 23139358.

Pignatelli P, Carnevale R, Di Santo S, et al. Rosuvastatin reduces platelet recruitment by inhibiting NADPH oxidase activation. Biochem Pharmacol. 2012 Dec 15;84(12):1635-42. PMID: 23022230.

Laumen H, Skurk T, Hauner H. The HMG-CoA reductase inhibitor rosuvastatin inhibits plasminogen activator inhibitor-1 expression and secretion in human adipocytes. Atherosclerosis. 2008 Feb;196(2):565-73. PMID: 17692320.

Holdgate GA, Ward WH, McTaggart F. Molecular mechanism for inhibition of 3-hydroxy-3-methylglutaryl CoA (HMG-CoA) reductase by rosuvastatin. Biochem Soc Trans. 2003 Jun;31(Pt 3):528-31. PMID: 12773150.

Izumi S, Nozaki Y, Maeda K, et al. Investigation of the impact of substrate selection on in vitro organic anion transporting polypeptide 1B1 inhibition profiles for the prediction of drug-drug interactions. Drug Metab Dispos. 2015 Feb;43(2):235-247. PMID: 25414411.

" Not dangerous goods.

LKT R5974 Rosuvastatin Calcium 250 mg 712.6 Statin; HMG-CoA reductase inhibitor, potential NADPH oxidase and PKC inhibitor. "(S-((R*,S*-(E)))- 7-(4-(4-fluorophenyl)-6-(1-methylethyl)-2-

(methyl(methylsulfonyl) amino)-5-pyrimidinyl)-3,5-dihydroxy-

6-heptenoic acid, calcium salt (2:1) " 147098-20-2 ≥98% 1001.14 2(C22H28FN3O6S) Ca2+ CC(C)C1=NC(=NC(=C1C=CC(CC(CC(=O)[O-])O)O)C2=CC=C(C=C2)F)N(C)S(=O)(=O)C.CC(C)C1=NC(=NC(=C1C=CC(CC(CC(=O)[O-])O)O)C2=CC=C(C=C2)F)N(C)S(=O)(=O)C.[Ca+2] Ambient Ambient Slightly soluble in water, marginally soluble in ethanol,soluble in DMSO(100mg/mL), DMF "Li Y, Wang Q, Zhou J, et al. Rosuvastatin attenuates atherosclerosis in rats via activation of scavenger receptor class B type I. Eur J Pharmacol. 2013 Dec 10;723C:23-28. [Epub ahead of print]. PMID: 24333476.

Luo B, Li B, Wang W, et al. Rosuvastatin Alleviates Diabetic Cardiomyopathy by Inhibiting NLRP3 Inflammasome and MAPK Pathways in a Type 2 Diabetes Rat Model. Cardiovasc Drugs Ther. 2013 Nov 20. [Epub ahead of print]. PMID: 24254031.

Gan J, Li P, Wang Z, et al. Rosuvastatin suppresses platelet-derived growth factor-BB-induced vascular smooth muscle cell proliferation and migration via the MAPK signaling pathway. Exp Ther Med. 2013 Oct;6(4):899-903. PMID: 24137286.

Hu X, Sun A, Xie X, et al. Rosuvastatin changes cytokine expressions in ischemic territory and preserves heart function after acute myocardial infarction in rats. J Cardiovasc Pharmacol Ther. 2013 Mar;18(2):162-76. PMID: 23139358.

Pignatelli P, Carnevale R, Di Santo S, et al. Rosuvastatin reduces platelet recruitment by inhibiting NADPH oxidase activation. Biochem Pharmacol. 2012 Dec 15;84(12):1635-42. PMID: 23022230.

Laumen H, Skurk T, Hauner H. The HMG-CoA reductase inhibitor rosuvastatin inhibits plasminogen activator inhibitor-1 expression and secretion in human adipocytes. Atherosclerosis. 2008 Feb;196(2):565-73. PMID: 17692320.

Holdgate GA, Ward WH, McTaggart F. Molecular mechanism for inhibition of 3-hydroxy-3-methylglutaryl CoA (HMG-CoA) reductase by rosuvastatin. Biochem Soc Trans. 2003 Jun;31(Pt 3):528-31. PMID: 12773150.

Izumi S, Nozaki Y, Maeda K, et al. Investigation of the impact of substrate selection on in vitro organic anion transporting polypeptide 1B1 inhibition profiles for the prediction of drug-drug interactions. Drug Metab Dispos. 2015 Feb;43(2):235-247. PMID: 25414411.

" Not dangerous goods.

LKT R5894 Roxatidine Acetate Hydrochloride 100 mg 149.5 Histamine H2 antagonist. 2-Acetoxy-N-[3-[3-(1-piperidinylmethyl)phenoxy]- propyl]acetamide hydrochloride Pifatidine; Altat; Gastralgin; Roxit  93793-83-0 ≥98% 384.9 C19H28N2O4 HCl CC(=O)OCC(=O)NCCCOC1=CC=CC(=C1)CN2CCCCC2.Cl Ambient Ambient "Umegaki E, Yoda Y, Tokioka S, et al. Protective effect of roxatidine against indomethacin-induced small intestinal mucosal injury in rats. J Gastroenterol Hepatol. 2010 May;25 Suppl 1:S35-40. PMID: 20586863.

Murdoch D, McTavish D. Roxatidine acetate. A review of its pharmacodynamic and pharmacokinetic properties, and its therapeutic potential in peptic ulcer disease and related disorders. Drugs. 1991 Aug;42(2):240-60. PMID: 1717223.

" Not dangerous goods.

LKT R5894 Roxatidine Acetate Hydrochloride 500 mg 434.9 Histamine H2 antagonist. 2-Acetoxy-N-[3-[3-(1-piperidinylmethyl)phenoxy]- propyl]acetamide hydrochloride Pifatidine; Altat; Gastralgin; Roxit  93793-83-0 ≥98% 384.9 C19H28N2O4 HCl CC(=O)OCC(=O)NCCCOC1=CC=CC(=C1)CN2CCCCC2.Cl Ambient Ambient "Umegaki E, Yoda Y, Tokioka S, et al. Protective effect of roxatidine against indomethacin-induced small intestinal mucosal injury in rats. J Gastroenterol Hepatol. 2010 May;25 Suppl 1:S35-40. PMID: 20586863.

Murdoch D, McTavish D. Roxatidine acetate. A review of its pharmacodynamic and pharmacokinetic properties, and its therapeutic potential in peptic ulcer disease and related disorders. Drugs. 1991 Aug;42(2):240-60. PMID: 1717223.

" Not dangerous goods.

LKT R5894 Roxatidine Acetate Hydrochloride 1 g 679.5 Histamine H2 antagonist. 2-Acetoxy-N-[3-[3-(1-piperidinylmethyl)phenoxy]- propyl]acetamide hydrochloride Pifatidine; Altat; Gastralgin; Roxit  93793-83-0 ≥98% 384.9 C19H28N2O4 HCl CC(=O)OCC(=O)NCCCOC1=CC=CC(=C1)CN2CCCCC2.Cl Ambient Ambient "Umegaki E, Yoda Y, Tokioka S, et al. Protective effect of roxatidine against indomethacin-induced small intestinal mucosal injury in rats. J Gastroenterol Hepatol. 2010 May;25 Suppl 1:S35-40. PMID: 20586863.

Murdoch D, McTavish D. Roxatidine acetate. A review of its pharmacodynamic and pharmacokinetic properties, and its therapeutic potential in peptic ulcer disease and related disorders. Drugs. 1991 Aug;42(2):240-60. PMID: 1717223.

" Not dangerous goods.

LKT R5874 Rosmarinic Acid 10 mg 40.7 Caffeic acid ester found in Melissa, Salvia, and Rosmarinus; GABA transaminase and Fyn kinase inhibitor. 3,4-Dihydroxycinnamic acid 2-ester with 3-(3,4-dihydroxy- phenyl)lactic acid Rosemary acid 20283-92-5 ≥98% 360.31 C18H16O8 C1=CC(=C(C=C1CC(C(=O)O)OC(=O)C=CC2=CC(=C(C=C2)O)O)O)O Ambient -20°C Soluble in DMSO, ethanol, dimethyl formamide, or PBS. "Airoldi C, Sironi E, Dias C, et al. Natural compounds against Alzheimer's disease: molecular recognition of Aβ1-42 peptide by Salvia sclareoides extract and its major component, rosmarinic acid, as investigated by NMR. Chem Asian J. 2013 Mar;8(3):596-602. PMID: 23303581.

Anusuya C, Manoharan S. Antitumor initiating potential of rosmarinic acid in 7,12-dimethylbenz(a)anthracene-induced hamster buccal pouch carcinogenesis. J Environ Pathol Toxicol Oncol. 2011;30(3):199-211. PMID: 22126613.

Oh HA, Park CS, Ahn HJ, et al. Effect of Perilla frutescens var. acuta Kudo and rosmarinic acid on allergic inflammatory reactions. Exp Biol Med (Maywood). 2011 Jan;236(1):99-106. PMID: 21239739.

Li GS, Jiang WL, Tian JW, et al. In vitro and in vivo antifibrotic effects of rosmarinic acid on experimental liver fibrosis. Phytomedicine. 2010 Mar;17(3-4):282-8. PMID: 19524418.

Ito N, Yabe T, Gamo Y, et al. Rosmarinic acid from Perillae Herba produces an antidepressant-like effect in mice through cell proliferation in the hippocampus. Biol Pharm Bull. 2008 Jul;31(7):1376-80. PMID: 18591778.

Jelić D, Mildner B, Kostrun S, et al. Homology modeling of human Fyn kinase structure: discovery of rosmarinic acid as a new Fyn kinase inhibitor and in silico study of its possible binding modes. J Med Chem. 2007 Mar 22;50(6):1090-100. PMID: 17315853.

Huang SS, Zheng RL. Rosmarinic acid inhibits angiogenesis and its mechanism of action in vitro. Cancer Lett. 2006 Aug 8;239(2):271-80. PMID: 16239062.

" None Not dangerous goods.

LKT R5874 Rosmarinic Acid 25 mg 81.6 Caffeic acid ester found in Melissa, Salvia, and Rosmarinus; GABA transaminase and Fyn kinase inhibitor. 3,4-Dihydroxycinnamic acid 2-ester with 3-(3,4-dihydroxy- phenyl)lactic acid Rosemary acid 20283-92-5 ≥98% 360.31 C18H16O8 C1=CC(=C(C=C1CC(C(=O)O)OC(=O)C=CC2=CC(=C(C=C2)O)O)O)O Ambient -20°C Soluble in DMSO, ethanol, dimethyl formamide, or PBS. "Airoldi C, Sironi E, Dias C, et al. Natural compounds against Alzheimer's disease: molecular recognition of Aβ1-42 peptide by Salvia sclareoides extract and its major component, rosmarinic acid, as investigated by NMR. Chem Asian J. 2013 Mar;8(3):596-602. PMID: 23303581.

Anusuya C, Manoharan S. Antitumor initiating potential of rosmarinic acid in 7,12-dimethylbenz(a)anthracene-induced hamster buccal pouch carcinogenesis. J Environ Pathol Toxicol Oncol. 2011;30(3):199-211. PMID: 22126613.

Oh HA, Park CS, Ahn HJ, et al. Effect of Perilla frutescens var. acuta Kudo and rosmarinic acid on allergic inflammatory reactions. Exp Biol Med (Maywood). 2011 Jan;236(1):99-106. PMID: 21239739.

Li GS, Jiang WL, Tian JW, et al. In vitro and in vivo antifibrotic effects of rosmarinic acid on experimental liver fibrosis. Phytomedicine. 2010 Mar;17(3-4):282-8. PMID: 19524418.

Ito N, Yabe T, Gamo Y, et al. Rosmarinic acid from Perillae Herba produces an antidepressant-like effect in mice through cell proliferation in the hippocampus. Biol Pharm Bull. 2008 Jul;31(7):1376-80. PMID: 18591778.

Jelić D, Mildner B, Kostrun S, et al. Homology modeling of human Fyn kinase structure: discovery of rosmarinic acid as a new Fyn kinase inhibitor and in silico study of its possible binding modes. J Med Chem. 2007 Mar 22;50(6):1090-100. PMID: 17315853.

Huang SS, Zheng RL. Rosmarinic acid inhibits angiogenesis and its mechanism of action in vitro. Cancer Lett. 2006 Aug 8;239(2):271-80. PMID: 16239062.

" None Not dangerous goods.

LKT R5874 Rosmarinic Acid 100 mg 237.8 Caffeic acid ester found in Melissa, Salvia, and Rosmarinus; GABA transaminase and Fyn kinase inhibitor. 3,4-Dihydroxycinnamic acid 2-ester with 3-(3,4-dihydroxy- phenyl)lactic acid Rosemary acid 20283-92-5 ≥98% 360.31 C18H16O8 C1=CC(=C(C=C1CC(C(=O)O)OC(=O)C=CC2=CC(=C(C=C2)O)O)O)O Ambient -20°C Soluble in DMSO, ethanol, dimethyl formamide, or PBS. "Airoldi C, Sironi E, Dias C, et al. Natural compounds against Alzheimer's disease: molecular recognition of Aβ1-42 peptide by Salvia sclareoides extract and its major component, rosmarinic acid, as investigated by NMR. Chem Asian J. 2013 Mar;8(3):596-602. PMID: 23303581.

Anusuya C, Manoharan S. Antitumor initiating potential of rosmarinic acid in 7,12-dimethylbenz(a)anthracene-induced hamster buccal pouch carcinogenesis. J Environ Pathol Toxicol Oncol. 2011;30(3):199-211. PMID: 22126613.

Oh HA, Park CS, Ahn HJ, et al. Effect of Perilla frutescens var. acuta Kudo and rosmarinic acid on allergic inflammatory reactions. Exp Biol Med (Maywood). 2011 Jan;236(1):99-106. PMID: 21239739.

Li GS, Jiang WL, Tian JW, et al. In vitro and in vivo antifibrotic effects of rosmarinic acid on experimental liver fibrosis. Phytomedicine. 2010 Mar;17(3-4):282-8. PMID: 19524418.

Ito N, Yabe T, Gamo Y, et al. Rosmarinic acid from Perillae Herba produces an antidepressant-like effect in mice through cell proliferation in the hippocampus. Biol Pharm Bull. 2008 Jul;31(7):1376-80. PMID: 18591778.

Jelić D, Mildner B, Kostrun S, et al. Homology modeling of human Fyn kinase structure: discovery of rosmarinic acid as a new Fyn kinase inhibitor and in silico study of its possible binding modes. J Med Chem. 2007 Mar 22;50(6):1090-100. PMID: 17315853.

Huang SS, Zheng RL. Rosmarinic acid inhibits angiogenesis and its mechanism of action in vitro. Cancer Lett. 2006 Aug 8;239(2):271-80. PMID: 16239062.

" None Not dangerous goods.

LKT R5774 Roscovitine 1 mg 68 CDK inhibitor, L-type Ca2+ channel blocker. "2-(R)-(1-Ethyl-2-hydroxyethylamino)-6-benzylamino- 9-isopropylpurine

" Seliciclib, CYC202 186692-46-6 ≥98% 354.45 C19H26N6O CCC(CO)NC1=NC2=C(C(=N1)NCC3=CC=CC=C3)N=CN2C(C)C Ambient Soluble in DMSO or chloroform. "Leitch AE, Haslett C, Rossi AG. Cyclin-dependent kinase inhibitor drugs as potential novel anti-inflammatory and pro-resolution agents. Br J Pharmacol. 2009 Oct;158(4):1004-16. PMID: 19775281.

Yarotskyy V, Elmslie KS. Roscovitine, a cyclin-dependent kinase inhibitor, affects several gating mechanisms to inhibit cardiac L-type (Ca(V)1.2) calcium channels. Br J Pharmacol. 2007 Oct;152(3):386-95. PMID: 17700718.

Lacrima K, Rinaldi A, Vignati S, et al. Cyclin-dependent kinase inhibitor seliciclib shows in vitro activity in diffuse large B-cell lymphomas. Leuk Lymphoma. 2007 Jan;48(1):158-67. PMID: 17325859.

" Xi Not dangerous goods.

LKT R5774 Roscovitine 5 mg 135 CDK inhibitor, L-type Ca2+ channel blocker. "2-(R)-(1-Ethyl-2-hydroxyethylamino)-6-benzylamino- 9-isopropylpurine

" Seliciclib, CYC202 186692-46-6 ≥98% 354.45 C19H26N6O CCC(CO)NC1=NC2=C(C(=N1)NCC3=CC=CC=C3)N=CN2C(C)C Ambient Soluble in DMSO or chloroform. "Leitch AE, Haslett C, Rossi AG. Cyclin-dependent kinase inhibitor drugs as potential novel anti-inflammatory and pro-resolution agents. Br J Pharmacol. 2009 Oct;158(4):1004-16. PMID: 19775281.

Yarotskyy V, Elmslie KS. Roscovitine, a cyclin-dependent kinase inhibitor, affects several gating mechanisms to inhibit cardiac L-type (Ca(V)1.2) calcium channels. Br J Pharmacol. 2007 Oct;152(3):386-95. PMID: 17700718.

Lacrima K, Rinaldi A, Vignati S, et al. Cyclin-dependent kinase inhibitor seliciclib shows in vitro activity in diffuse large B-cell lymphomas. Leuk Lymphoma. 2007 Jan;48(1):158-67. PMID: 17325859.

" Xi Not dangerous goods.

LKT R5774 Roscovitine 10 mg 200 CDK inhibitor, L-type Ca2+ channel blocker. "2-(R)-(1-Ethyl-2-hydroxyethylamino)-6-benzylamino- 9-isopropylpurine

" Seliciclib, CYC202 186692-46-6 ≥98% 354.45 C19H26N6O CCC(CO)NC1=NC2=C(C(=N1)NCC3=CC=CC=C3)N=CN2C(C)C Ambient Soluble in DMSO or chloroform. "Leitch AE, Haslett C, Rossi AG. Cyclin-dependent kinase inhibitor drugs as potential novel anti-inflammatory and pro-resolution agents. Br J Pharmacol. 2009 Oct;158(4):1004-16. PMID: 19775281.

Yarotskyy V, Elmslie KS. Roscovitine, a cyclin-dependent kinase inhibitor, affects several gating mechanisms to inhibit cardiac L-type (Ca(V)1.2) calcium channels. Br J Pharmacol. 2007 Oct;152(3):386-95. PMID: 17700718.

Lacrima K, Rinaldi A, Vignati S, et al. Cyclin-dependent kinase inhibitor seliciclib shows in vitro activity in diffuse large B-cell lymphomas. Leuk Lymphoma. 2007 Jan;48(1):158-67. PMID: 17325859.

" Xi Not dangerous goods.

LKT R5773 Rosiglitazone 500 mg 165.1 Thiazolidinedione; PPARγ agonist. 5-[[4-[2-(Methyl-2-pyridinylamino)ethoxy]phenyl]- methyl]-2,4-thiazolidinedione BRL-49653 122320-73-4 ≥98% 357.43 C18H19N3O3S CN(CCOC1=CC=C(C=C1)CC2C(=O)NC(=O)S2)C3=CC=CC=N3 Ambient Ambient Soluble in ethanol and in buffered aqueous solutions (pH of 2.3). "Rui M, Huang Z, Liu Y, et al. Rosiglitazone suppresses angiogenesis in multiple myeloma via downregulation of hypoxia inducible factor 1α and insulin like growth factor 1 mRNA expression. Mol Med Rep. 2014 Jul 22. [Epub ahead of print]. PMID: 25050627.

Mingfeng D, Xiaodong M, Yue L, et al. Effects of PPAR-γ Agonist Treatment on LPS-Induced Mastitis in Rats. Inflammation. 2014 May 18. [Epub ahead of print]. PMID: 24839089.

Liu Y, Tian XY, Huang Y, et al. Rosiglitazone Attenuated Endothelin-1-Induced Vasoconstriction of Pulmonary Arteries in the Rat Model of Pulmonary Arterial Hypertension via Differential Regulation of ET-1 Receptors. PPAR Res. 2014;2014:374075. PMID: 24701204.

He H, Tao H, Xiong H, et al. Rosiglitazone causes cardiotoxicity via peroxisome proliferator-activated receptor γ-independent mitochondrial oxidative stress in mouse hearts. Toxicol Sci. 2014 Apr;138(2):468-81. PMID: 24449420.

Hou X, Zhang Y, Shen YH, et al. PPAR-γ activation by rosiglitazone suppresses angiotensin II-mediated proliferation and phenotypictransition in cardiac fibroblasts via inhibition of activation of activator protein 1. Eur J Pharmacol. 2013 Sep 5;715(1-3):196-203. PMID: 23791613.

" None Not dangerous goods.

LKT R5773 Rosiglitazone 1 g 268.2 Thiazolidinedione; PPARγ agonist. 5-[[4-[2-(Methyl-2-pyridinylamino)ethoxy]phenyl]- methyl]-2,4-thiazolidinedione BRL-49653 122320-73-4 ≥98% 357.43 C18H19N3O3S CN(CCOC1=CC=C(C=C1)CC2C(=O)NC(=O)S2)C3=CC=CC=N3 Ambient Ambient Soluble in ethanol and in buffered aqueous solutions (pH of 2.3). "Rui M, Huang Z, Liu Y, et al. Rosiglitazone suppresses angiogenesis in multiple myeloma via downregulation of hypoxia inducible factor 1α and insulin like growth factor 1 mRNA expression. Mol Med Rep. 2014 Jul 22. [Epub ahead of print]. PMID: 25050627.

Mingfeng D, Xiaodong M, Yue L, et al. Effects of PPAR-γ Agonist Treatment on LPS-Induced Mastitis in Rats. Inflammation. 2014 May 18. [Epub ahead of print]. PMID: 24839089.

Liu Y, Tian XY, Huang Y, et al. Rosiglitazone Attenuated Endothelin-1-Induced Vasoconstriction of Pulmonary Arteries in the Rat Model of Pulmonary Arterial Hypertension via Differential Regulation of ET-1 Receptors. PPAR Res. 2014;2014:374075. PMID: 24701204.

He H, Tao H, Xiong H, et al. Rosiglitazone causes cardiotoxicity via peroxisome proliferator-activated receptor γ-independent mitochondrial oxidative stress in mouse hearts. Toxicol Sci. 2014 Apr;138(2):468-81. PMID: 24449420.

Hou X, Zhang Y, Shen YH, et al. PPAR-γ activation by rosiglitazone suppresses angiotensin II-mediated proliferation and phenotypictransition in cardiac fibroblasts via inhibition of activation of activator protein 1. Eur J Pharmacol. 2013 Sep 5;715(1-3):196-203. PMID: 23791613.

" None Not dangerous goods.

LKT R5773 Rosiglitazone 5 g 825.1 Thiazolidinedione; PPARγ agonist. 5-[[4-[2-(Methyl-2-pyridinylamino)ethoxy]phenyl]- methyl]-2,4-thiazolidinedione BRL-49653 122320-73-4 ≥98% 357.43 C18H19N3O3S CN(CCOC1=CC=C(C=C1)CC2C(=O)NC(=O)S2)C3=CC=CC=N3 Ambient Ambient Soluble in ethanol and in buffered aqueous solutions (pH of 2.3). "Rui M, Huang Z, Liu Y, et al. Rosiglitazone suppresses angiogenesis in multiple myeloma via downregulation of hypoxia inducible factor 1α and insulin like growth factor 1 mRNA expression. Mol Med Rep. 2014 Jul 22. [Epub ahead of print]. PMID: 25050627.

Mingfeng D, Xiaodong M, Yue L, et al. Effects of PPAR-γ Agonist Treatment on LPS-Induced Mastitis in Rats. Inflammation. 2014 May 18. [Epub ahead of print]. PMID: 24839089.

Liu Y, Tian XY, Huang Y, et al. Rosiglitazone Attenuated Endothelin-1-Induced Vasoconstriction of Pulmonary Arteries in the Rat Model of Pulmonary Arterial Hypertension via Differential Regulation of ET-1 Receptors. PPAR Res. 2014;2014:374075. PMID: 24701204.

He H, Tao H, Xiong H, et al. Rosiglitazone causes cardiotoxicity via peroxisome proliferator-activated receptor γ-independent mitochondrial oxidative stress in mouse hearts. Toxicol Sci. 2014 Apr;138(2):468-81. PMID: 24449420.

Hou X, Zhang Y, Shen YH, et al. PPAR-γ activation by rosiglitazone suppresses angiotensin II-mediated proliferation and phenotypictransition in cardiac fibroblasts via inhibition of activation of activator protein 1. Eur J Pharmacol. 2013 Sep 5;715(1-3):196-203. PMID: 23791613.

" None Not dangerous goods.

LKT R5772 Rosiglitazone Maleate 500 mg 163.2 Thiazolidinedione; PPARγ agonist. 5-[[4-[2-(Methyl-2-pyridinylamino)ethoxy]phenyl]methyl]-2,4-thiazolidinedione BRL-49653c; Avandia 155141-29-0 ≥98% 473.51 C18H19N3O3S C4H4O4 CN(CCOC1=CC=C(C=C1)CC2C(=O)NC(=O)S2)C3=CC=CC=N3.C(=CC(=O)O)C(=O)O Ambient Ambient Readily soluble in ethanol and in buffered aqueous solutions with a pH of 2.3. "Rui M, Huang Z, Liu Y, et al. Rosiglitazone suppresses angiogenesis in multiple myeloma via downregulation of hypoxia inducible factor 1α and insulin like growth factor 1 mRNA expression. Mol Med Rep. 2014 Jul 22. [Epub ahead of print]. PMID: 25050627.

Mingfeng D, Xiaodong M, Yue L, et al. Effects of PPAR-γ Agonist Treatment on LPS-Induced Mastitis in Rats. Inflammation. 2014 May 18. [Epub ahead of print]. PMID: 24839089.

Liu Y, Tian XY, Huang Y, et al. Rosiglitazone Attenuated Endothelin-1-Induced Vasoconstriction of Pulmonary Arteries in the Rat Model of Pulmonary Arterial Hypertension via Differential Regulation of ET-1 Receptors. PPAR Res. 2014;2014:374075. PMID: 24701204.

He H, Tao H, Xiong H, et al. Rosiglitazone causes cardiotoxicity via peroxisome proliferator-activated receptor γ-independent mitochondrial oxidative stress in mouse hearts. Toxicol Sci. 2014 Apr;138(2):468-81. PMID: 24449420.

Hou X, Zhang Y, Shen YH, et al. PPAR-γ activation by rosiglitazone suppresses angiotensin II-mediated proliferation and phenotypictransition in cardiac fibroblasts via inhibition of activation of activator protein 1. Eur J Pharmacol. 2013 Sep 5;715(1-3):196-203. PMID: 23791613.

Sharma AN, Elased KM, Lucot JB. Rosiglitazone treatment reversed depression- but not psychosis-like behavior of db/db diabetic mice. J Psychopharmacol. 2012 May;26(5):724-732. PMID: 22331176.

" Xn "UN number: 3077     Class: 9     Packing Group: III

Proper shipping name: Environmentally hazardous substance, solid, n.o.s. (Rosiglitazone maleate)"

LKT R5772 Rosiglitazone Maleate 1 g 237.8 Thiazolidinedione; PPARγ agonist. 5-[[4-[2-(Methyl-2-pyridinylamino)ethoxy]phenyl]methyl]-2,4-thiazolidinedione BRL-49653c; Avandia 155141-29-0 ≥98% 473.51 C18H19N3O3S C4H4O4 CN(CCOC1=CC=C(C=C1)CC2C(=O)NC(=O)S2)C3=CC=CC=N3.C(=CC(=O)O)C(=O)O Ambient Ambient Readily soluble in ethanol and in buffered aqueous solutions with a pH of 2.3. "Rui M, Huang Z, Liu Y, et al. Rosiglitazone suppresses angiogenesis in multiple myeloma via downregulation of hypoxia inducible factor 1α and insulin like growth factor 1 mRNA expression. Mol Med Rep. 2014 Jul 22. [Epub ahead of print]. PMID: 25050627.

Mingfeng D, Xiaodong M, Yue L, et al. Effects of PPAR-γ Agonist Treatment on LPS-Induced Mastitis in Rats. Inflammation. 2014 May 18. [Epub ahead of print]. PMID: 24839089.

Liu Y, Tian XY, Huang Y, et al. Rosiglitazone Attenuated Endothelin-1-Induced Vasoconstriction of Pulmonary Arteries in the Rat Model of Pulmonary Arterial Hypertension via Differential Regulation of ET-1 Receptors. PPAR Res. 2014;2014:374075. PMID: 24701204.

He H, Tao H, Xiong H, et al. Rosiglitazone causes cardiotoxicity via peroxisome proliferator-activated receptor γ-independent mitochondrial oxidative stress in mouse hearts. Toxicol Sci. 2014 Apr;138(2):468-81. PMID: 24449420.

Hou X, Zhang Y, Shen YH, et al. PPAR-γ activation by rosiglitazone suppresses angiotensin II-mediated proliferation and phenotypictransition in cardiac fibroblasts via inhibition of activation of activator protein 1. Eur J Pharmacol. 2013 Sep 5;715(1-3):196-203. PMID: 23791613.

Sharma AN, Elased KM, Lucot JB. Rosiglitazone treatment reversed depression- but not psychosis-like behavior of db/db diabetic mice. J Psychopharmacol. 2012 May;26(5):724-732. PMID: 22331176.

" Xn "UN number: 3077     Class: 9     Packing Group: III

Proper shipping name: Environmentally hazardous substance, solid, n.o.s. (Rosiglitazone maleate)"

LKT R5772 Rosiglitazone Maleate 5 g 611.5 Thiazolidinedione; PPARγ agonist. 5-[[4-[2-(Methyl-2-pyridinylamino)ethoxy]phenyl]methyl]-2,4-thiazolidinedione BRL-49653c; Avandia 155141-29-0 ≥98% 473.51 C18H19N3O3S C4H4O4 CN(CCOC1=CC=C(C=C1)CC2C(=O)NC(=O)S2)C3=CC=CC=N3.C(=CC(=O)O)C(=O)O Ambient Ambient Readily soluble in ethanol and in buffered aqueous solutions with a pH of 2.3. "Rui M, Huang Z, Liu Y, et al. Rosiglitazone suppresses angiogenesis in multiple myeloma via downregulation of hypoxia inducible factor 1α and insulin like growth factor 1 mRNA expression. Mol Med Rep. 2014 Jul 22. [Epub ahead of print]. PMID: 25050627.

Mingfeng D, Xiaodong M, Yue L, et al. Effects of PPAR-γ Agonist Treatment on LPS-Induced Mastitis in Rats. Inflammation. 2014 May 18. [Epub ahead of print]. PMID: 24839089.

Liu Y, Tian XY, Huang Y, et al. Rosiglitazone Attenuated Endothelin-1-Induced Vasoconstriction of Pulmonary Arteries in the Rat Model of Pulmonary Arterial Hypertension via Differential Regulation of ET-1 Receptors. PPAR Res. 2014;2014:374075. PMID: 24701204.

He H, Tao H, Xiong H, et al. Rosiglitazone causes cardiotoxicity via peroxisome proliferator-activated receptor γ-independent mitochondrial oxidative stress in mouse hearts. Toxicol Sci. 2014 Apr;138(2):468-81. PMID: 24449420.

Hou X, Zhang Y, Shen YH, et al. PPAR-γ activation by rosiglitazone suppresses angiotensin II-mediated proliferation and phenotypictransition in cardiac fibroblasts via inhibition of activation of activator protein 1. Eur J Pharmacol. 2013 Sep 5;715(1-3):196-203. PMID: 23791613.

Sharma AN, Elased KM, Lucot JB. Rosiglitazone treatment reversed depression- but not psychosis-like behavior of db/db diabetic mice. J Psychopharmacol. 2012 May;26(5):724-732. PMID: 22331176.

" Xn "UN number: 3077     Class: 9     Packing Group: III

Proper shipping name: Environmentally hazardous substance, solid, n.o.s. (Rosiglitazone maleate)"

LKT R5722 Rofecoxib 1 g 305.9 NSAID; COX-2 inhibitor. 4-[4-(Methylsulfonyl)-phenyl]-3-phenyl-2(5H)- furanone "Vioxx

" 162011-90-7 ≥98% 314.36 C17H14O4S CS(=O)(=O)C1=CC=C(C=C1)C2=C(C(=O)OC2)C3=CC=CC=C3 Ambient Ambient Slightly soluble in methanol and acetone. Insoluble in water. "D'Arca D, LeNoir J, Wildemore B, et al. Prevention of urinary bladder cancer in the FHIT knock-out mouse with Rofecoxib, a Cox-2 inhibitor. Urol Oncol. 2010 Mar-Apr;28(2):189-94. PMID: 19372053.

Akula KK, Dhir A, Kulkarni SK. Rofecoxib, a selective cyclooxygenase-2 (COX-2) inhibitor increases pentylenetetrazol seizure threshold in mice: possible involvement of adenosinergic mechanism. Epilepsy Res. 2008 Jan;78(1):60-70. PMID: 18054463." Not dangerous goods.

LKT N0061 D-Naproxen  5 g 46.2 NSAID; COX-1/2 inhibitor. S(+)6-Methoxy-α methyl-2-naphthaleneacetic acid S-Naproxen, Nonyl; Equiproxen; Napren; Pranoxen 22204-53-1 ≥98% 230.26 C14H14O3 CC(C1=CC2=C(C=C1)C=C(C=C2)OC)C(=O)O Ambient 4°C Soluble in ethanol and acetone. Insoluble in water. "Lejal N, Tarus B, Bouguyon E, et al. Structure-based discovery of the novel antiviral properties of naproxen against the nucleoprotein of influenza A virus. Antimicrob Agents Chemother. 2013 May;57(5):2231-42. PMID: 23459490.

Duggan KC, Walters MJ, Musee J, et al. Molecular basis for cyclooxygenase inhibition by the non-steroidal anti-inflammatory drug naproxen. J Biol Chem. 2010 Nov 5;285(45):34950-9. PMID: 20810665.

" Xn "UN number: 2811     Class:  6.1     Packing group:  III

Proper shipping name:  Toxic Solids, organic, n.o.s. (Naproxen)

Marine pollutant:  No     Poison Inhalation:  No

"

LKT N0061 D-Naproxen  25 g 115.6 NSAID; COX-1/2 inhibitor. S(+)6-Methoxy-α methyl-2-naphthaleneacetic acid S-Naproxen, Nonyl; Equiproxen; Napren; Pranoxen 22204-53-1 ≥98% 230.26 C14H14O3 CC(C1=CC2=C(C=C1)C=C(C=C2)OC)C(=O)O Ambient 4°C Soluble in ethanol and acetone. Insoluble in water. "Lejal N, Tarus B, Bouguyon E, et al. Structure-based discovery of the novel antiviral properties of naproxen against the nucleoprotein of influenza A virus. Antimicrob Agents Chemother. 2013 May;57(5):2231-42. PMID: 23459490.

Duggan KC, Walters MJ, Musee J, et al. Molecular basis for cyclooxygenase inhibition by the non-steroidal anti-inflammatory drug naproxen. J Biol Chem. 2010 Nov 5;285(45):34950-9. PMID: 20810665.

" Xn "UN number: 2811     Class:  6.1     Packing group:  III

Proper shipping name:  Toxic Solids, organic, n.o.s. (Naproxen)

Marine pollutant:  No     Poison Inhalation:  No

"

LKT N0061 D-Naproxen  50 g 202.2 NSAID; COX-1/2 inhibitor. S(+)6-Methoxy-α methyl-2-naphthaleneacetic acid S-Naproxen, Nonyl; Equiproxen; Napren; Pranoxen 22204-53-1 ≥98% 230.26 C14H14O3 CC(C1=CC2=C(C=C1)C=C(C=C2)OC)C(=O)O Ambient 4°C Soluble in ethanol and acetone. Insoluble in water. "Lejal N, Tarus B, Bouguyon E, et al. Structure-based discovery of the novel antiviral properties of naproxen against the nucleoprotein of influenza A virus. Antimicrob Agents Chemother. 2013 May;57(5):2231-42. PMID: 23459490.

Duggan KC, Walters MJ, Musee J, et al. Molecular basis for cyclooxygenase inhibition by the non-steroidal anti-inflammatory drug naproxen. J Biol Chem. 2010 Nov 5;285(45):34950-9. PMID: 20810665.

" Xn "UN number: 2811     Class:  6.1     Packing group:  III

Proper shipping name:  Toxic Solids, organic, n.o.s. (Naproxen)

Marine pollutant:  No     Poison Inhalation:  No

"

LKT N0068 Naringenin 5 g 84.9 "Flavonone found in species of Citrus. 

Naringenin is natural. The source of this material is Citrus grands." 2,3-Dihydro-5,7-dihydroxy-2-(4-hydroxyphenyl)4H-1-benzopyran-4-one 4',5,7-Trihydroxyflavanone; naringetol; salipurpol; pelargidanon 1602 67604-48-2 ≥98% 272.25 C15H12O5 C1C(OC2=CC(=CC(=C2C1=O)O)O)C3=CC=C(C=C3)O Ambient Ambient Insoluble in water. Soluble in ethanol (50 mg/ml), DMSO, methanol. "Esmaeili MA, Alilou M. Naringenin attenuates CCl4 -induced hepatic inflammation by the activation of an Nrf2-mediated pathway in rats. Clin Exp Pharmacol Physiol. 2014 Jun;41(6):416-22. PMID: 24684352.

Chtourou Y, Fetoui H, Gdoura R. Protective effects of naringenin on iron-overload-induced cerebral cortex neurotoxicity correlated with oxidative stress. Biol Trace Elem Res. 2014 Jun;158(3):376-83. PMID: 24682942.

Lou H, Jing X, Wei X, et al. Naringenin protects against 6-OHDA-induced neurotoxicity via activation of the Nrf2/ARE signaling pathway. Neuropharmacology. 2014 Apr;79:380-8. PMID: 24333330.

Kim S, Park TI. Naringenin: a partial agonist on estrogen receptor in T47D-KBluc breast cancer cells. Int J Clin Exp Med. 2013 Oct 25;6(10):890-9. PMID: 24260594.

Yilma AN, Singh SR, Morici L, et al. Flavonoid naringenin: a potential immunomodulator for Chlamydia trachomatis inflammation. Mediators Inflamm. 2013;2013:102457. PMID: 23766556.

Jang Y, Kim SW, Oh J, et al. Ghrelin receptor is activated by naringin and naringenin, constituents of a prokinetic agent Poncirus fructus. J Ethnopharmacol. 2013 Jul 9;148(2):459-65. PMID: 23639361.

Jung JW, Park IH, Cho JS, et al. Naringenin inhibits extracellular matrix production via extracellular signal-regulated kinase pathways in nasal polyp-derived fibroblasts. Phytother Res. 2013 Mar;27(3):463-7. PMID: 22674629.

Goldwasser J, Cohen PY, Lin W, et al. Naringenin inhibits the assembly and long-term production of infectious hepatitis C virus particles through a PPAR-mediated mechanism. J Hepatol. 2011 Nov;55(5):963-71. PMID: 21354229.

Qin L, Jin L, Lu L, et al. Naringenin reduces lung metastasis in a breast cancer resection model. Protein Cell. 2011 Jun;2(6):507-16. PMID: 21748601.

Yi LT, Li CF, Zhan X, et al. Involvement of monoaminergic system in the antidepressant-like effect of the flavonoid naringenin in mice. Prog Neuropsychopharmacol Biol Psychiatry. 2010 Oct 1;34(7):1223-8. PMID: 20603175.

Shi Y, Dai J, Liu H, et al. Naringenin inhibits allergen-induced airway inflammation and airway responsiveness and inhibits NF-kappaB activity in a murine model of asthma. Can J Physiol Pharmacol. 2009 Sep;87(9):729-35PMID: 19794524.

Park JH, Jin CY, Lee BK, et al. Naringenin induces apoptosis through downregulation of Akt and caspase-3 activation in human leukemia THP-1 cells. Food Chem Toxicol. 2008 Dec;46(12):3684-90. PMID: 18930780.

" Xn, Xi Not dangerous goods.

LKT N0068 Naringenin 10 g 109.2 "Flavonone found in species of Citrus. 

Naringenin is natural. The source of this material is Citrus grands." 2,3-Dihydro-5,7-dihydroxy-2-(4-hydroxyphenyl)4H-1-benzopyran-4-one 4',5,7-Trihydroxyflavanone; naringetol; salipurpol; pelargidanon 1602 67604-48-2 ≥98% 272.25 C15H12O5 C1C(OC2=CC(=CC(=C2C1=O)O)O)C3=CC=C(C=C3)O Ambient Ambient Insoluble in water. Soluble in ethanol (50 mg/ml), DMSO, methanol. "Esmaeili MA, Alilou M. Naringenin attenuates CCl4 -induced hepatic inflammation by the activation of an Nrf2-mediated pathway in rats. Clin Exp Pharmacol Physiol. 2014 Jun;41(6):416-22. PMID: 24684352.

Chtourou Y, Fetoui H, Gdoura R. Protective effects of naringenin on iron-overload-induced cerebral cortex neurotoxicity correlated with oxidative stress. Biol Trace Elem Res. 2014 Jun;158(3):376-83. PMID: 24682942.

Lou H, Jing X, Wei X, et al. Naringenin protects against 6-OHDA-induced neurotoxicity via activation of the Nrf2/ARE signaling pathway. Neuropharmacology. 2014 Apr;79:380-8. PMID: 24333330.

Kim S, Park TI. Naringenin: a partial agonist on estrogen receptor in T47D-KBluc breast cancer cells. Int J Clin Exp Med. 2013 Oct 25;6(10):890-9. PMID: 24260594.

Yilma AN, Singh SR, Morici L, et al. Flavonoid naringenin: a potential immunomodulator for Chlamydia trachomatis inflammation. Mediators Inflamm. 2013;2013:102457. PMID: 23766556.

Jang Y, Kim SW, Oh J, et al. Ghrelin receptor is activated by naringin and naringenin, constituents of a prokinetic agent Poncirus fructus. J Ethnopharmacol. 2013 Jul 9;148(2):459-65. PMID: 23639361.

Jung JW, Park IH, Cho JS, et al. Naringenin inhibits extracellular matrix production via extracellular signal-regulated kinase pathways in nasal polyp-derived fibroblasts. Phytother Res. 2013 Mar;27(3):463-7. PMID: 22674629.

Goldwasser J, Cohen PY, Lin W, et al. Naringenin inhibits the assembly and long-term production of infectious hepatitis C virus particles through a PPAR-mediated mechanism. J Hepatol. 2011 Nov;55(5):963-71. PMID: 21354229.

Qin L, Jin L, Lu L, et al. Naringenin reduces lung metastasis in a breast cancer resection model. Protein Cell. 2011 Jun;2(6):507-16. PMID: 21748601.

Yi LT, Li CF, Zhan X, et al. Involvement of monoaminergic system in the antidepressant-like effect of the flavonoid naringenin in mice. Prog Neuropsychopharmacol Biol Psychiatry. 2010 Oct 1;34(7):1223-8. PMID: 20603175.

Shi Y, Dai J, Liu H, et al. Naringenin inhibits allergen-induced airway inflammation and airway responsiveness and inhibits NF-kappaB activity in a murine model of asthma. Can J Physiol Pharmacol. 2009 Sep;87(9):729-35PMID: 19794524.

Park JH, Jin CY, Lee BK, et al. Naringenin induces apoptosis through downregulation of Akt and caspase-3 activation in human leukemia THP-1 cells. Food Chem Toxicol. 2008 Dec;46(12):3684-90. PMID: 18930780.

" Xn, Xi Not dangerous goods.

LKT N0068 Naringenin 25 g 242.7 "Flavonone found in species of Citrus. 

Naringenin is natural. The source of this material is Citrus grands." 2,3-Dihydro-5,7-dihydroxy-2-(4-hydroxyphenyl)4H-1-benzopyran-4-one 4',5,7-Trihydroxyflavanone; naringetol; salipurpol; pelargidanon 1602 67604-48-2 ≥98% 272.25 C15H12O5 C1C(OC2=CC(=CC(=C2C1=O)O)O)C3=CC=C(C=C3)O Ambient Ambient Insoluble in water. Soluble in ethanol (50 mg/ml), DMSO, methanol. "Esmaeili MA, Alilou M. Naringenin attenuates CCl4 -induced hepatic inflammation by the activation of an Nrf2-mediated pathway in rats. Clin Exp Pharmacol Physiol. 2014 Jun;41(6):416-22. PMID: 24684352.

Chtourou Y, Fetoui H, Gdoura R. Protective effects of naringenin on iron-overload-induced cerebral cortex neurotoxicity correlated with oxidative stress. Biol Trace Elem Res. 2014 Jun;158(3):376-83. PMID: 24682942.

Lou H, Jing X, Wei X, et al. Naringenin protects against 6-OHDA-induced neurotoxicity via activation of the Nrf2/ARE signaling pathway. Neuropharmacology. 2014 Apr;79:380-8. PMID: 24333330.

Kim S, Park TI. Naringenin: a partial agonist on estrogen receptor in T47D-KBluc breast cancer cells. Int J Clin Exp Med. 2013 Oct 25;6(10):890-9. PMID: 24260594.

Yilma AN, Singh SR, Morici L, et al. Flavonoid naringenin: a potential immunomodulator for Chlamydia trachomatis inflammation. Mediators Inflamm. 2013;2013:102457. PMID: 23766556.

Jang Y, Kim SW, Oh J, et al. Ghrelin receptor is activated by naringin and naringenin, constituents of a prokinetic agent Poncirus fructus. J Ethnopharmacol. 2013 Jul 9;148(2):459-65. PMID: 23639361.

Jung JW, Park IH, Cho JS, et al. Naringenin inhibits extracellular matrix production via extracellular signal-regulated kinase pathways in nasal polyp-derived fibroblasts. Phytother Res. 2013 Mar;27(3):463-7. PMID: 22674629.

Goldwasser J, Cohen PY, Lin W, et al. Naringenin inhibits the assembly and long-term production of infectious hepatitis C virus particles through a PPAR-mediated mechanism. J Hepatol. 2011 Nov;55(5):963-71. PMID: 21354229.

Qin L, Jin L, Lu L, et al. Naringenin reduces lung metastasis in a breast cancer resection model. Protein Cell. 2011 Jun;2(6):507-16. PMID: 21748601.

Yi LT, Li CF, Zhan X, et al. Involvement of monoaminergic system in the antidepressant-like effect of the flavonoid naringenin in mice. Prog Neuropsychopharmacol Biol Psychiatry. 2010 Oct 1;34(7):1223-8. PMID: 20603175.

Shi Y, Dai J, Liu H, et al. Naringenin inhibits allergen-induced airway inflammation and airway responsiveness and inhibits NF-kappaB activity in a murine model of asthma. Can J Physiol Pharmacol. 2009 Sep;87(9):729-35PMID: 19794524.

Park JH, Jin CY, Lee BK, et al. Naringenin induces apoptosis through downregulation of Akt and caspase-3 activation in human leukemia THP-1 cells. Food Chem Toxicol. 2008 Dec;46(12):3684-90. PMID: 18930780.

" Xn, Xi Not dangerous goods.

LKT R5611 Rocuronium Bromide 10 mg 47.6 Non-depolarizing NMJ blocker; nAChR and M2/3 mAChR antagonist. 119302-91-9 ≥98% 609.68 C32H53BrN2O4 CC(=O)OC1C(CC2C1(CCC3C2CCC4C3(CC(C(C4)O)N5CCOCC5)C)C)[N+]6(CCCC6)CC=C.[Br-] Ambient Ambient Water "Pape A, Kertscho H, Stein P, et al. Neuromuscular blockade with rocuronium bromide increases the tolerance of acute normovolemic anemia in anesthetized pigs. Eur Surg Res. 2012;48(1):16-25. PMID: 22189343.

Bowman WC. Neuromuscular block. Br J Pharmacol. 2006 Jan;147 Suppl 1:S277-86. PMID: 16402115.

Hou VY, Hirshman CA, Emala CW. Neuromuscular relaxants as antagonists for M2 and M3 muscarinic receptors. Anesthesiology. 1998 Mar;88(3):744-50. PMID: 9523819.

" Not dangerous goods.

LKT R5611 Rocuronium Bromide 25 mg 81.6 Non-depolarizing NMJ blocker; nAChR and M2/3 mAChR antagonist. 119302-91-9 ≥98% 609.68 C32H53BrN2O4 CC(=O)OC1C(CC2C1(CCC3C2CCC4C3(CC(C(C4)O)N5CCOCC5)C)C)[N+]6(CCCC6)CC=C.[Br-] Ambient Ambient Water "Pape A, Kertscho H, Stein P, et al. Neuromuscular blockade with rocuronium bromide increases the tolerance of acute normovolemic anemia in anesthetized pigs. Eur Surg Res. 2012;48(1):16-25. PMID: 22189343.

Bowman WC. Neuromuscular block. Br J Pharmacol. 2006 Jan;147 Suppl 1:S277-86. PMID: 16402115.

Hou VY, Hirshman CA, Emala CW. Neuromuscular relaxants as antagonists for M2 and M3 muscarinic receptors. Anesthesiology. 1998 Mar;88(3):744-50. PMID: 9523819.

" Not dangerous goods.

LKT R5611 Rocuronium Bromide 100 mg 205.1 Non-depolarizing NMJ blocker; nAChR and M2/3 mAChR antagonist. 119302-91-9 ≥98% 609.68 C32H53BrN2O4 CC(=O)OC1C(CC2C1(CCC3C2CCC4C3(CC(C(C4)O)N5CCOCC5)C)C)[N+]6(CCCC6)CC=C.[Br-] Ambient Ambient Water "Pape A, Kertscho H, Stein P, et al. Neuromuscular blockade with rocuronium bromide increases the tolerance of acute normovolemic anemia in anesthetized pigs. Eur Surg Res. 2012;48(1):16-25. PMID: 22189343.

Bowman WC. Neuromuscular block. Br J Pharmacol. 2006 Jan;147 Suppl 1:S277-86. PMID: 16402115.

Hou VY, Hirshman CA, Emala CW. Neuromuscular relaxants as antagonists for M2 and M3 muscarinic receptors. Anesthesiology. 1998 Mar;88(3):744-50. PMID: 9523819.

" Not dangerous goods.

LKT N0062 D,L-Naproxen 10 g 67.6 NSAID; COX-1/2 inhibitor. (+)-(S)-6-Methoxy-α-methyl-2-naphthaleneacetic acid Artagen; Danaprox; Nafasol; Sutolin ≥96% 230.26 C14H14O3 CC(C1=CC2=C(C=C1)C=C(C=C2)OC)C(=O)O Ambient 4°C Insoluble in water. Soluble in acetone or ethanol. "Lejal N, Tarus B, Bouguyon E, et al. Structure-based discovery of the novel antiviral properties of naproxen against the nucleoprotein of influenza A virus. Antimicrob Agents Chemother. 2013 May;57(5):2231-42. PMID: 23459490.

Duggan KC, Walters MJ, Musee J, et al. Molecular basis for cyclooxygenase inhibition by the non-steroidal anti-inflammatory drug naproxen. J Biol Chem. 2010 Nov 5;285(45):34950-9. PMID: 20810665.

" Xn "UN number: 2811     Class: 6.1     Packing Group: III

Proper shipping name: Toxic solid, organic, n.o.s. (Naproxen)

Poison Inhalation Hazard: No"

LKT N0062 D,L-Naproxen 25 g 151.8 NSAID; COX-1/2 inhibitor. (+)-(S)-6-Methoxy-α-methyl-2-naphthaleneacetic acid Artagen; Danaprox; Nafasol; Sutolin ≥96% 230.26 C14H14O3 CC(C1=CC2=C(C=C1)C=C(C=C2)OC)C(=O)O Ambient 4°C Insoluble in water. Soluble in acetone or ethanol. "Lejal N, Tarus B, Bouguyon E, et al. Structure-based discovery of the novel antiviral properties of naproxen against the nucleoprotein of influenza A virus. Antimicrob Agents Chemother. 2013 May;57(5):2231-42. PMID: 23459490.

Duggan KC, Walters MJ, Musee J, et al. Molecular basis for cyclooxygenase inhibition by the non-steroidal anti-inflammatory drug naproxen. J Biol Chem. 2010 Nov 5;285(45):34950-9. PMID: 20810665.

" Xn "UN number: 2811     Class: 6.1     Packing Group: III

Proper shipping name: Toxic solid, organic, n.o.s. (Naproxen)

Poison Inhalation Hazard: No"

LKT N0062 D,L-Naproxen 100 g 480 NSAID; COX-1/2 inhibitor. (+)-(S)-6-Methoxy-α-methyl-2-naphthaleneacetic acid Artagen; Danaprox; Nafasol; Sutolin ≥96% 230.26 C14H14O3 CC(C1=CC2=C(C=C1)C=C(C=C2)OC)C(=O)O Ambient 4°C Insoluble in water. Soluble in acetone or ethanol. "Lejal N, Tarus B, Bouguyon E, et al. Structure-based discovery of the novel antiviral properties of naproxen against the nucleoprotein of influenza A virus. Antimicrob Agents Chemother. 2013 May;57(5):2231-42. PMID: 23459490.

Duggan KC, Walters MJ, Musee J, et al. Molecular basis for cyclooxygenase inhibition by the non-steroidal anti-inflammatory drug naproxen. J Biol Chem. 2010 Nov 5;285(45):34950-9. PMID: 20810665.

" Xn "UN number: 2811     Class: 6.1     Packing Group: III

Proper shipping name: Toxic solid, organic, n.o.s. (Naproxen)

Poison Inhalation Hazard: No"

LKT N0069 Naringin 25 g 47.6 Flavanone glycoside found in citrus fruit; SERM. 7-[[2-O-(6-Deoxy-α-L-mannopyranosyl)-β-D-gluco- pyranosyl]oxy]-2,3-dihydro-5-hydroxy-2-(4-hydroxy- phenyl)-4H-1-benzopyran-4-one Naringenin-7-rhamnoglucoside; Aurantiin 10236-47-2 ≥97% 580.53 C27H32O14 CC1C(C(C(C(O1)OC2C(C(C(OC2OC3=CC(=C4C(=O)CC(OC4=C3)C5=CC=C(C=C5)O)O)CO)O)O)O)O)O Ambient Ambient Soluble in water (1 mg/ml), alcohol, acetone, and warm acetic acid "Sahu BD, Tatireddy S, Koneru M, et al. Naringin ameliorates gentamicin-induced nephrotoxicity and associated mitochondrial dysfunction, apoptosis and inflammation in rats: possible mechanism of nephroprotection. Toxicol Appl Pharmacol. 2014 May 15;277(1):8-20. PMID: 24637089.

Li H, Yang B, Huang J, et al. Naringin inhibits growth potential of human triple-negative breast cancer cells by targeting β-catenin signaling pathway. Toxicol Lett. 2013 Jul 18;220(3):219-28. PMID: 23694763.

Wang DM, Yang YJ, Zhang L, et al. Naringin Enhances CaMKII Activity and Improves Long-Term Memory in a Mouse Model of Alzheimer's Disease. Int J Mol Sci. 2013 Mar 11;14(3):5576-86. PMID: 23478434.

Guo D, Wang J, Wang X, et al. Double directional adjusting estrogenic effect of naringin from Rhizoma drynariae (Gusuibu). J Ethnopharmacol. 2011 Nov 18;138(2):451-7. PMID: 21964193.

Kumar A, Dogra S, Prakash A. Protective effect of naringin, a citrus flavonoid, against colchicine-induced cognitive dysfunction and oxidative damage in rats. J Med Food. 2010 Aug;13(4):976-84. PMID: 20673063.

Schindler R, Mentlein R. Flavonoids and vitamin E reduce the release of the angiogenic peptide vascular endothelial growth factor from human tumor cells. J Nutr. 2006 Jun;136(6):1477-82. PMID: 16702307.

" Xi Not dangerous goods.

LKT N0069 Naringin 100 g 136 Flavanone glycoside found in citrus fruit; SERM. 7-[[2-O-(6-Deoxy-α-L-mannopyranosyl)-β-D-gluco- pyranosyl]oxy]-2,3-dihydro-5-hydroxy-2-(4-hydroxy- phenyl)-4H-1-benzopyran-4-one Naringenin-7-rhamnoglucoside; Aurantiin 10236-47-2 ≥97% 580.53 C27H32O14 CC1C(C(C(C(O1)OC2C(C(C(OC2OC3=CC(=C4C(=O)CC(OC4=C3)C5=CC=C(C=C5)O)O)CO)O)O)O)O)O Ambient Ambient Soluble in water (1 mg/ml), alcohol, acetone, and warm acetic acid "Sahu BD, Tatireddy S, Koneru M, et al. Naringin ameliorates gentamicin-induced nephrotoxicity and associated mitochondrial dysfunction, apoptosis and inflammation in rats: possible mechanism of nephroprotection. Toxicol Appl Pharmacol. 2014 May 15;277(1):8-20. PMID: 24637089.

Li H, Yang B, Huang J, et al. Naringin inhibits growth potential of human triple-negative breast cancer cells by targeting β-catenin signaling pathway. Toxicol Lett. 2013 Jul 18;220(3):219-28. PMID: 23694763.

Wang DM, Yang YJ, Zhang L, et al. Naringin Enhances CaMKII Activity and Improves Long-Term Memory in a Mouse Model of Alzheimer's Disease. Int J Mol Sci. 2013 Mar 11;14(3):5576-86. PMID: 23478434.

Guo D, Wang J, Wang X, et al. Double directional adjusting estrogenic effect of naringin from Rhizoma drynariae (Gusuibu). J Ethnopharmacol. 2011 Nov 18;138(2):451-7. PMID: 21964193.

Kumar A, Dogra S, Prakash A. Protective effect of naringin, a citrus flavonoid, against colchicine-induced cognitive dysfunction and oxidative damage in rats. J Med Food. 2010 Aug;13(4):976-84. PMID: 20673063.

Schindler R, Mentlein R. Flavonoids and vitamin E reduce the release of the angiogenic peptide vascular endothelial growth factor from human tumor cells. J Nutr. 2006 Jun;136(6):1477-82. PMID: 16702307.

" Xi Not dangerous goods.

LKT R3586 Rivastigmine Tartrate 100 mg 149.9 AChE and BChE inhibitor. (2R,3R)-2,3-dihydroxybutanedioic acid;[3-[(1S)-1-(dimethylamino)ethyl]phenyl] N-ethyl-N-methylcarbamate 129101-54-8 ≥98% 400.43 C18H28N2O8 CCN(C)C(=O)OC1=CC=CC(=C1)C(C)N(C)C.C(C(C(=O)O)O)(C(=O)O)O Ambient Ambient "Moriguchi S, Tagashira H, Sasaki Y, et al. CaMKII activity is essential for improvement of memory-related behaviors by chronic rivastigmine treatment. J Neurochem. 2013 Oct 28. [Epub ahead of print]. PMID: 24164423.

Bailey JA, Ray B, Greig NH, et al. Rivastigmine lowers Aβ and increases sAPPα levels, which parallel elevated synaptic markers and metabolic activity in degenerating primary rat neurons. PLoS One. 2011;6(7):e21954. PMID: 21799757.

Pollak Y, Gilboa A, Ben-Menachem O, et al. Acetylcholinesterase inhibitors reduce brain and blood interleukin-1beta production. Ann Neurol. 2005 May;57(5):741-5. PMID: 15852394.

Krall WJ, Sramek JJ, Cutler NR. Cholinesterase inhibitors: a therapeutic strategy for Alzheimer disease. Ann Pharmacother. 1999 Apr;33(4):441-50. PMID: 10332536.

" "UN number: 2811     Class: 6.1     Packing Group: III

Proper shipping name: Toxic solid, organic, n.o.s. (Rivastigmine tartrate)"

LKT R3586 Rivastigmine Tartrate 250 mg 300.1 AChE and BChE inhibitor. (2R,3R)-2,3-dihydroxybutanedioic acid;[3-[(1S)-1-(dimethylamino)ethyl]phenyl] N-ethyl-N-methylcarbamate 129101-54-8 ≥98% 400.43 C18H28N2O8 CCN(C)C(=O)OC1=CC=CC(=C1)C(C)N(C)C.C(C(C(=O)O)O)(C(=O)O)O Ambient Ambient "Moriguchi S, Tagashira H, Sasaki Y, et al. CaMKII activity is essential for improvement of memory-related behaviors by chronic rivastigmine treatment. J Neurochem. 2013 Oct 28. [Epub ahead of print]. PMID: 24164423.

Bailey JA, Ray B, Greig NH, et al. Rivastigmine lowers Aβ and increases sAPPα levels, which parallel elevated synaptic markers and metabolic activity in degenerating primary rat neurons. PLoS One. 2011;6(7):e21954. PMID: 21799757.

Pollak Y, Gilboa A, Ben-Menachem O, et al. Acetylcholinesterase inhibitors reduce brain and blood interleukin-1beta production. Ann Neurol. 2005 May;57(5):741-5. PMID: 15852394.

Krall WJ, Sramek JJ, Cutler NR. Cholinesterase inhibitors: a therapeutic strategy for Alzheimer disease. Ann Pharmacother. 1999 Apr;33(4):441-50. PMID: 10332536.

" "UN number: 2811     Class: 6.1     Packing Group: III

Proper shipping name: Toxic solid, organic, n.o.s. (Rivastigmine tartrate)"

LKT R3586 Rivastigmine Tartrate 1 g 937.5 AChE and BChE inhibitor. (2R,3R)-2,3-dihydroxybutanedioic acid;[3-[(1S)-1-(dimethylamino)ethyl]phenyl] N-ethyl-N-methylcarbamate 129101-54-8 ≥98% 400.43 C18H28N2O8 CCN(C)C(=O)OC1=CC=CC(=C1)C(C)N(C)C.C(C(C(=O)O)O)(C(=O)O)O Ambient Ambient "Moriguchi S, Tagashira H, Sasaki Y, et al. CaMKII activity is essential for improvement of memory-related behaviors by chronic rivastigmine treatment. J Neurochem. 2013 Oct 28. [Epub ahead of print]. PMID: 24164423.

Bailey JA, Ray B, Greig NH, et al. Rivastigmine lowers Aβ and increases sAPPα levels, which parallel elevated synaptic markers and metabolic activity in degenerating primary rat neurons. PLoS One. 2011;6(7):e21954. PMID: 21799757.

Pollak Y, Gilboa A, Ben-Menachem O, et al. Acetylcholinesterase inhibitors reduce brain and blood interleukin-1beta production. Ann Neurol. 2005 May;57(5):741-5. PMID: 15852394.

Krall WJ, Sramek JJ, Cutler NR. Cholinesterase inhibitors: a therapeutic strategy for Alzheimer disease. Ann Pharmacother. 1999 Apr;33(4):441-50. PMID: 10332536.

" "UN number: 2811     Class: 6.1     Packing Group: III

Proper shipping name: Toxic solid, organic, n.o.s. (Rivastigmine tartrate)"

LKT N0075 Natamycin 25 mg 189 Polyene macrolide; ergosterol inhibitor. "16-(3-Amino-3,6-didesoxy-beta-D-mannopyranosyloxy)-5,6-

epoxy-8,12,14-trihydroxy-26-methyl-2,10-dioxo-1-

oxacyclohexacosa-3,17,19,21,23-pentaen-13-carbonsaeure" Pimaricin; Tennecetin; Mycophyt; Myprozine; Natacyn; Pimafucin. 7681-93-8 ≥98% 665.73 C33H47NO13 CC1CC=CC=CC=CC=CC(CC2C(C(CC(O2)(CC(CC3C(O3)C=CC(=O)O1)O)O)O)C(=O)O)OC4C(C(C(C(O4)C)O)N)O Protect from light. Ambient 4°C Soluble at 20oC in 87% glycerol (0.18g/mL). Practically insoluble in higher alcohols. "Kallinteri LD, Kostoula OK, Savvaidis IN. Efficacy of nisin and/or natamycin to improve the shelf-life of Galotyri cheese. Food Microbiol. 2013 Dec;36(2):176-81. PMID: 24010596.

Thomas PA, Kaliamurthy J. Mycotic keratitis: epidemiology, diagnosis and management. Clin Microbiol Infect. 2013 Mar;19(3):210-20. PMID: 23398543.

Darisipudi MN, Allam R, Rupanagudi KV, et al. Polyene macrolide antifungal drugs trigger interleukin-1β secretion by activating the NLRP3 inflammasome. PLoS One. 2011;6(5):e19588. PMID: 21625424.

Hammarström L, Smith CI. In vitro activating properties of polyene antibiotics for murine lymphocytes. Acta Pathol Microbiol Scand C. 1977 Aug;85C(4):277-83. PMID: 302553.

" Xn "Not dangerous goods.

"

LKT N0075 Natamycin 50 mg 315.1 Polyene macrolide; ergosterol inhibitor. "16-(3-Amino-3,6-didesoxy-beta-D-mannopyranosyloxy)-5,6-

epoxy-8,12,14-trihydroxy-26-methyl-2,10-dioxo-1-

oxacyclohexacosa-3,17,19,21,23-pentaen-13-carbonsaeure" Pimaricin; Tennecetin; Mycophyt; Myprozine; Natacyn; Pimafucin. 7681-93-8 ≥98% 665.73 C33H47NO13 CC1CC=CC=CC=CC=CC(CC2C(C(CC(O2)(CC(CC3C(O3)C=CC(=O)O1)O)O)O)C(=O)O)OC4C(C(C(C(O4)C)O)N)O Protect from light. Ambient 4°C Soluble at 20oC in 87% glycerol (0.18g/mL). Practically insoluble in higher alcohols. "Kallinteri LD, Kostoula OK, Savvaidis IN. Efficacy of nisin and/or natamycin to improve the shelf-life of Galotyri cheese. Food Microbiol. 2013 Dec;36(2):176-81. PMID: 24010596.

Thomas PA, Kaliamurthy J. Mycotic keratitis: epidemiology, diagnosis and management. Clin Microbiol Infect. 2013 Mar;19(3):210-20. PMID: 23398543.

Darisipudi MN, Allam R, Rupanagudi KV, et al. Polyene macrolide antifungal drugs trigger interleukin-1β secretion by activating the NLRP3 inflammasome. PLoS One. 2011;6(5):e19588. PMID: 21625424.

Hammarström L, Smith CI. In vitro activating properties of polyene antibiotics for murine lymphocytes. Acta Pathol Microbiol Scand C. 1977 Aug;85C(4):277-83. PMID: 302553.

" Xn "Not dangerous goods.

"

LKT N0075 Natamycin 100 mg 577.6 Polyene macrolide; ergosterol inhibitor. "16-(3-Amino-3,6-didesoxy-beta-D-mannopyranosyloxy)-5,6-

epoxy-8,12,14-trihydroxy-26-methyl-2,10-dioxo-1-

oxacyclohexacosa-3,17,19,21,23-pentaen-13-carbonsaeure" Pimaricin; Tennecetin; Mycophyt; Myprozine; Natacyn; Pimafucin. 7681-93-8 ≥98% 665.73 C33H47NO13 CC1CC=CC=CC=CC=CC(CC2C(C(CC(O2)(CC(CC3C(O3)C=CC(=O)O1)O)O)O)C(=O)O)OC4C(C(C(C(O4)C)O)N)O Protect from light. Ambient 4°C Soluble at 20oC in 87% glycerol (0.18g/mL). Practically insoluble in higher alcohols. "Kallinteri LD, Kostoula OK, Savvaidis IN. Efficacy of nisin and/or natamycin to improve the shelf-life of Galotyri cheese. Food Microbiol. 2013 Dec;36(2):176-81. PMID: 24010596.

Thomas PA, Kaliamurthy J. Mycotic keratitis: epidemiology, diagnosis and management. Clin Microbiol Infect. 2013 Mar;19(3):210-20. PMID: 23398543.

Darisipudi MN, Allam R, Rupanagudi KV, et al. Polyene macrolide antifungal drugs trigger interleukin-1β secretion by activating the NLRP3 inflammasome. PLoS One. 2011;6(5):e19588. PMID: 21625424.

Hammarström L, Smith CI. In vitro activating properties of polyene antibiotics for murine lymphocytes. Acta Pathol Microbiol Scand C. 1977 Aug;85C(4):277-83. PMID: 302553.

" Xn "Not dangerous goods.

"

LKT R3577 Ritonavir 100 mg 56.3 HIV protease inhibitor. Norvir 155213-67-5 ≥98% 720.95 C37H48N6O5S2 CC(C)C1=NC(=CS1)CN(C)C(=O)NC(C(C)C)C(=O)NC(CC2=CC=CC=C2)CC(C(CC3=CC=CC=C3)NC(=O)OCC4=CN=CS4)O Ambient Ambient DMSO to 10 mg/mL, Ethanol to 3 mg/mL, Methanol "Vadlapatla RK, Vadlapudi AD, Pal D, et al. Ritonavir inhibits HIF-1α-mediated VEGF expression in retinal pigment epithelial cells in vitro. Eye (Lond). 2013 Nov 8. [Epub ahead of print]. PMID: 24202050.

Kao E, Shinohara M, Feng M, et al. Human immunodeficiency virus protease inhibitors modulate Ca2+ homeostasis and potentiate alcoholic stress and injury in mice and primary mouse and human hepatocytes. Hepatology. 2012 Aug;56(2):594-604. PMID: 22407670.

Hisatomi T, Nakazawa T, Noda K, et al. HIV protease inhibitors provide neuroprotection through inhibition of mitochondrial apoptosis in mice. J Clin Invest. 2008 Jun;118(6):2025-38. PMID: 18497877.

Grigem S, Fischer-Posovszky P, Debatin KM, et al. The effect of the HIV protease inhibitor ritonavir on proliferation, differentiation, lipogenesis, gene expression and apoptosis of human preadipocytes and adipocytes. Horm Metab Res. 2005 Oct;37(10):602-9. PMID: 16278782.

Riddle TM, Schildmeyer NM, Phan C, et al. The HIV protease inhibitor ritonavir increases lipoprotein production and has no effect on lipoprotein clearance in mice. J Lipid Res. 2002 Sep;43(9):1458-63. PMID: 12235177.

Beach JW. Chemotherapeutic agents for human immunodeficiency virus infection: mechanism of action, pharmacokinetics, metabolism, and adverse reactions. Clin Ther. 1998 Jan-Feb;20(1):2-25. PMID: 9522101.

Kawakami K, Harada T, Yoshihashi Y, et al. Correlation between glass-forming ability and fragility of pharmaceutical compounds. J Phys Chem B. 2015 Apr 9;119(14):4873-4880. PMID: 25781503.

" Xn Not dangerous goods.

LKT R3577 Ritonavir 250 mg 112.5 HIV protease inhibitor. Norvir 155213-67-5 ≥98% 720.95 C37H48N6O5S2 CC(C)C1=NC(=CS1)CN(C)C(=O)NC(C(C)C)C(=O)NC(CC2=CC=CC=C2)CC(C(CC3=CC=CC=C3)NC(=O)OCC4=CN=CS4)O Ambient Ambient DMSO to 10 mg/mL, Ethanol to 3 mg/mL, Methanol "Vadlapatla RK, Vadlapudi AD, Pal D, et al. Ritonavir inhibits HIF-1α-mediated VEGF expression in retinal pigment epithelial cells in vitro. Eye (Lond). 2013 Nov 8. [Epub ahead of print]. PMID: 24202050.

Kao E, Shinohara M, Feng M, et al. Human immunodeficiency virus protease inhibitors modulate Ca2+ homeostasis and potentiate alcoholic stress and injury in mice and primary mouse and human hepatocytes. Hepatology. 2012 Aug;56(2):594-604. PMID: 22407670.

Hisatomi T, Nakazawa T, Noda K, et al. HIV protease inhibitors provide neuroprotection through inhibition of mitochondrial apoptosis in mice. J Clin Invest. 2008 Jun;118(6):2025-38. PMID: 18497877.

Grigem S, Fischer-Posovszky P, Debatin KM, et al. The effect of the HIV protease inhibitor ritonavir on proliferation, differentiation, lipogenesis, gene expression and apoptosis of human preadipocytes and adipocytes. Horm Metab Res. 2005 Oct;37(10):602-9. PMID: 16278782.

Riddle TM, Schildmeyer NM, Phan C, et al. The HIV protease inhibitor ritonavir increases lipoprotein production and has no effect on lipoprotein clearance in mice. J Lipid Res. 2002 Sep;43(9):1458-63. PMID: 12235177.

Beach JW. Chemotherapeutic agents for human immunodeficiency virus infection: mechanism of action, pharmacokinetics, metabolism, and adverse reactions. Clin Ther. 1998 Jan-Feb;20(1):2-25. PMID: 9522101.

Kawakami K, Harada T, Yoshihashi Y, et al. Correlation between glass-forming ability and fragility of pharmaceutical compounds. J Phys Chem B. 2015 Apr 9;119(14):4873-4880. PMID: 25781503.

" Xn Not dangerous goods.

LKT R3577 Ritonavir 1 g 309.4 HIV protease inhibitor. Norvir 155213-67-5 ≥98% 720.95 C37H48N6O5S2 CC(C)C1=NC(=CS1)CN(C)C(=O)NC(C(C)C)C(=O)NC(CC2=CC=CC=C2)CC(C(CC3=CC=CC=C3)NC(=O)OCC4=CN=CS4)O Ambient Ambient DMSO to 10 mg/mL, Ethanol to 3 mg/mL, Methanol "Vadlapatla RK, Vadlapudi AD, Pal D, et al. Ritonavir inhibits HIF-1α-mediated VEGF expression in retinal pigment epithelial cells in vitro. Eye (Lond). 2013 Nov 8. [Epub ahead of print]. PMID: 24202050.

Kao E, Shinohara M, Feng M, et al. Human immunodeficiency virus protease inhibitors modulate Ca2+ homeostasis and potentiate alcoholic stress and injury in mice and primary mouse and human hepatocytes. Hepatology. 2012 Aug;56(2):594-604. PMID: 22407670.

Hisatomi T, Nakazawa T, Noda K, et al. HIV protease inhibitors provide neuroprotection through inhibition of mitochondrial apoptosis in mice. J Clin Invest. 2008 Jun;118(6):2025-38. PMID: 18497877.

Grigem S, Fischer-Posovszky P, Debatin KM, et al. The effect of the HIV protease inhibitor ritonavir on proliferation, differentiation, lipogenesis, gene expression and apoptosis of human preadipocytes and adipocytes. Horm Metab Res. 2005 Oct;37(10):602-9. PMID: 16278782.

Riddle TM, Schildmeyer NM, Phan C, et al. The HIV protease inhibitor ritonavir increases lipoprotein production and has no effect on lipoprotein clearance in mice. J Lipid Res. 2002 Sep;43(9):1458-63. PMID: 12235177.

Beach JW. Chemotherapeutic agents for human immunodeficiency virus infection: mechanism of action, pharmacokinetics, metabolism, and adverse reactions. Clin Ther. 1998 Jan-Feb;20(1):2-25. PMID: 9522101.

Kawakami K, Harada T, Yoshihashi Y, et al. Correlation between glass-forming ability and fragility of pharmaceutical compounds. J Phys Chem B. 2015 Apr 9;119(14):4873-4880. PMID: 25781503.

" Xn Not dangerous goods.

LKT R3477 Ritodrine Hydrochloride 250 mg 112.5 Phenylethylamine; β2-adrenergic agonist, SK/BK and ATP-sensitive K+ channel activator. Ritodrina, Ritodrinium 23239-51-2 ≥98% 323.82 C17H21NO3 HCl CC(C(C1=CC=C(C=C1)O)O)NCCC2=CC=C(C=C2)O.Cl Ambient Ambient "Sato Y, Teraki Y, Izaki S, et al. Ritodrine-induced erythematous papular eruption in 14 pregnant women. Int J Dermatol. 2010 Dec;49(12):1450-3. PMID: 21091685.

Schwarz MK, Page P. Preterm labour: an overview of current and emerging therapeutics. Curr Med Chem. 2003 Aug;10(15):1441-68. PMID: 12871140.

Hamada Y, Nakaya Y, Hamada S, et al. Activation of K+ channels by ritodrine hydrochloride in uterine smooth muscle cells from pregnant women. Eur J Pharmacol. 1994 Dec 15;288(1):45-51. PMID: 7705467.

Dubin NH, Ghodgaonkar RB. Effect of ritodrine hydrochloride and dibutyryl cyclic AMP on contractile activity and prostanoid production of uteri from pregnant rats in vitro. Prostaglandins Leukot Med. 1984 Feb;13(2):119-28. PMID: 6326162.

" Xn Not dangerous goods.

LKT R3477 Ritodrine Hydrochloride 1 g 346.9 Phenylethylamine; β2-adrenergic agonist, SK/BK and ATP-sensitive K+ channel activator. Ritodrina, Ritodrinium 23239-51-2 ≥98% 323.82 C17H21NO3 HCl CC(C(C1=CC=C(C=C1)O)O)NCCC2=CC=C(C=C2)O.Cl Ambient Ambient "Sato Y, Teraki Y, Izaki S, et al. Ritodrine-induced erythematous papular eruption in 14 pregnant women. Int J Dermatol. 2010 Dec;49(12):1450-3. PMID: 21091685.

Schwarz MK, Page P. Preterm labour: an overview of current and emerging therapeutics. Curr Med Chem. 2003 Aug;10(15):1441-68. PMID: 12871140.

Hamada Y, Nakaya Y, Hamada S, et al. Activation of K+ channels by ritodrine hydrochloride in uterine smooth muscle cells from pregnant women. Eur J Pharmacol. 1994 Dec 15;288(1):45-51. PMID: 7705467.

Dubin NH, Ghodgaonkar RB. Effect of ritodrine hydrochloride and dibutyryl cyclic AMP on contractile activity and prostanoid production of uteri from pregnant rats in vitro. Prostaglandins Leukot Med. 1984 Feb;13(2):119-28. PMID: 6326162.

" Xn Not dangerous goods.

LKT N0114 Nadifloxacin 25 mg 81.6 Fluoroquinolone; bacterial DNA gyrase inhibitor. "(+-)-9-Fluoro-6,7-dihydro-8-(4-hydroxypiperidino)-5-methyl-

1-oxo-1H,5H-benzo(ij)quinolizine-2-carboxylic acid" Jinofloxacin; Acuatim 124858-35-1 ≥98% 360.38 C19H21FN2O4 CC1CCC2=C3N1C=C(C(=O)C3=CC(=C2N4CCC(CC4)O)F)C(=O)O Ambient Ambient Soluble in DMSO. "Takenaka Y, Hayashi N, Takeda M, et al. Glycolic acid chemical peeling improves inflammatory acne eruptions through its inhibitory and bactericidal effects on Propionibacterium acnes. J Dermatol. 2012 Apr;39(4):350-4. PMID: 21950544.

Kuwahara K, Kitazawa T, Kitagaki H, et al. Nadifloxacin, an antiacne quinolone antimicrobial, inhibits the production of proinflammatory cytokines by human peripheral blood mononuclear cells and normal human keratinocytes. J Dermatol Sci. 2005 Apr;38(1):47-55. PMID: 15795123.

Akamatsu H, Sasaki H, Kurokawa I, et al. Effect of nadifloxacin on neutrophil functions. J Int Med Res. 1995 Jan-Feb;23(1):19-26. PMID: 7774755.

" Not dangerous goods.

LKT R3477 Ritodrine Hydrochloride 5 g 1125.1 Phenylethylamine; β2-adrenergic agonist, SK/BK and ATP-sensitive K+ channel activator. Ritodrina, Ritodrinium 23239-51-2 ≥98% 323.82 C17H21NO3 HCl CC(C(C1=CC=C(C=C1)O)O)NCCC2=CC=C(C=C2)O.Cl Ambient Ambient "Sato Y, Teraki Y, Izaki S, et al. Ritodrine-induced erythematous papular eruption in 14 pregnant women. Int J Dermatol. 2010 Dec;49(12):1450-3. PMID: 21091685.

Schwarz MK, Page P. Preterm labour: an overview of current and emerging therapeutics. Curr Med Chem. 2003 Aug;10(15):1441-68. PMID: 12871140.

Hamada Y, Nakaya Y, Hamada S, et al. Activation of K+ channels by ritodrine hydrochloride in uterine smooth muscle cells from pregnant women. Eur J Pharmacol. 1994 Dec 15;288(1):45-51. PMID: 7705467.

Dubin NH, Ghodgaonkar RB. Effect of ritodrine hydrochloride and dibutyryl cyclic AMP on contractile activity and prostanoid production of uteri from pregnant rats in vitro. Prostaglandins Leukot Med. 1984 Feb;13(2):119-28. PMID: 6326162.

" Xn Not dangerous goods.

LKT N0114 Nadifloxacin 100 mg 224.3 Fluoroquinolone; bacterial DNA gyrase inhibitor. "(+-)-9-Fluoro-6,7-dihydro-8-(4-hydroxypiperidino)-5-methyl-

1-oxo-1H,5H-benzo(ij)quinolizine-2-carboxylic acid" Jinofloxacin; Acuatim 124858-35-1 ≥98% 360.38 C19H21FN2O4 CC1CCC2=C3N1C=C(C(=O)C3=CC(=C2N4CCC(CC4)O)F)C(=O)O Ambient Ambient Soluble in DMSO. "Takenaka Y, Hayashi N, Takeda M, et al. Glycolic acid chemical peeling improves inflammatory acne eruptions through its inhibitory and bactericidal effects on Propionibacterium acnes. J Dermatol. 2012 Apr;39(4):350-4. PMID: 21950544.

Kuwahara K, Kitazawa T, Kitagaki H, et al. Nadifloxacin, an antiacne quinolone antimicrobial, inhibits the production of proinflammatory cytokines by human peripheral blood mononuclear cells and normal human keratinocytes. J Dermatol Sci. 2005 Apr;38(1):47-55. PMID: 15795123.

Akamatsu H, Sasaki H, Kurokawa I, et al. Effect of nadifloxacin on neutrophil functions. J Int Med Res. 1995 Jan-Feb;23(1):19-26. PMID: 7774755.

" Not dangerous goods.

LKT N0114 Nadifloxacin 500 mg 659.2 Fluoroquinolone; bacterial DNA gyrase inhibitor. "(+-)-9-Fluoro-6,7-dihydro-8-(4-hydroxypiperidino)-5-methyl-

1-oxo-1H,5H-benzo(ij)quinolizine-2-carboxylic acid" Jinofloxacin; Acuatim 124858-35-1 ≥98% 360.38 C19H21FN2O4 CC1CCC2=C3N1C=C(C(=O)C3=CC(=C2N4CCC(CC4)O)F)C(=O)O Ambient Ambient Soluble in DMSO. "Takenaka Y, Hayashi N, Takeda M, et al. Glycolic acid chemical peeling improves inflammatory acne eruptions through its inhibitory and bactericidal effects on Propionibacterium acnes. J Dermatol. 2012 Apr;39(4):350-4. PMID: 21950544.

Kuwahara K, Kitazawa T, Kitagaki H, et al. Nadifloxacin, an antiacne quinolone antimicrobial, inhibits the production of proinflammatory cytokines by human peripheral blood mononuclear cells and normal human keratinocytes. J Dermatol Sci. 2005 Apr;38(1):47-55. PMID: 15795123.

Akamatsu H, Sasaki H, Kurokawa I, et al. Effect of nadifloxacin on neutrophil functions. J Int Med Res. 1995 Jan-Feb;23(1):19-26. PMID: 7774755.

" Not dangerous goods.

LKT R3475 Risperidone 100 mg 93.8 Benzisoxazole; 5-HT7 and NMDA agonist, D-amino acid oxidase inhibitor, 5-HT2A and D2 antagonist. 3-[2-[4-(6-fluoro-1,2-benzoxazol-3-yl)piperidin-1-yl]ethyl]-2-methyl-6,7,8,9-tetrahydropyrido[2,1-b]pyrimidin-4-one 106266-06-2 ≥98% 410.49 C23H27FN4O2 CC1=C(C(=O)N2CCCCC2=N1)CCN3CCC(CC3)C4=NOC5=C4C=CC(=C5)F Ambient Ambient "Kamińska K, Gołembiowska K, Rogóż Z. Effect of risperidone on the fluoxetine-induced changes in extracellular dopamine, serotonin and noradrenaline in the rat frontal cortex. Pharmacol Rep. 2013;65(5):1144-51. PMID: 24399710.

MacDowell KS, García-Bueno B, Madrigal JL, et al. Risperidone normalizes increased inflammatory parameters and restores anti-inflammatory pathways in a model of neuroinflammation. Int J Neuropsychopharmacol. 2013 Feb;16(1):121-35. PMID: 22176740.

Kozielska M, Johnson M, Pilla Reddy V, et al. Pharmacokinetic-pharmacodynamic modeling of the D2 and 5-HT (2A) receptor occupancy of risperidone and paliperidone in rats. Pharm Res. 2012 Jul;29(7):1932-48. PMID: 22437487.

Abou El-Magd RM, Park HK, Kawazoe T, et al. The effect of risperidone on D-amino acid oxidase activity as a hypothesis for a novel mechanism of action in the treatment of schizophrenia. J Psychopharmacol. 2010 Jul;24(7):1055-67. PMID: 19329549.

Toohey N, Klein MT, Knight J, et al. Human 5-HT7 receptor-induced inactivation of forskolin-stimulated adenylate cyclase by risperidone, 9-OH-risperidone and other ""inactivating antagonists"". Mol Pharmacol. 2009 Sep;76(3):552-9. PMID: 19509219.

Potkin SG, Saha AR, Kujawa MJ, et al. Aripiprazole, an antipsychotic with a novel mechanism of action, and risperidone vs placebo in patients with schizophrenia and schizoaffective disorder. Arch Gen Psychiatry. 2003 Jul;60(7):681-90. PMID: 12860772.

Farde L, Nyberg S, Oxenstierna G, et al. Positron emission tomography studies on D2 and 5-HT2 receptor binding in risperidone-treated schizophrenic patients. J Clin Psychopharmacol. 1995 Feb;15(1 Suppl 1):19S-23S. PMID: 7537284.

" T "UN number: 2811     Class: 6.1     Packing Group: III

Proper shipping name: Toxic solid, organic, n.o.s. (Risperidone)"

LKT R3475 Risperidone 250 mg 178.1 Benzisoxazole; 5-HT7 and NMDA agonist, D-amino acid oxidase inhibitor, 5-HT2A and D2 antagonist. 3-[2-[4-(6-fluoro-1,2-benzoxazol-3-yl)piperidin-1-yl]ethyl]-2-methyl-6,7,8,9-tetrahydropyrido[2,1-b]pyrimidin-4-one 106266-06-2 ≥98% 410.49 C23H27FN4O2 CC1=C(C(=O)N2CCCCC2=N1)CCN3CCC(CC3)C4=NOC5=C4C=CC(=C5)F Ambient Ambient "Kamińska K, Gołembiowska K, Rogóż Z. Effect of risperidone on the fluoxetine-induced changes in extracellular dopamine, serotonin and noradrenaline in the rat frontal cortex. Pharmacol Rep. 2013;65(5):1144-51. PMID: 24399710.

MacDowell KS, García-Bueno B, Madrigal JL, et al. Risperidone normalizes increased inflammatory parameters and restores anti-inflammatory pathways in a model of neuroinflammation. Int J Neuropsychopharmacol. 2013 Feb;16(1):121-35. PMID: 22176740.

Kozielska M, Johnson M, Pilla Reddy V, et al. Pharmacokinetic-pharmacodynamic modeling of the D2 and 5-HT (2A) receptor occupancy of risperidone and paliperidone in rats. Pharm Res. 2012 Jul;29(7):1932-48. PMID: 22437487.

Abou El-Magd RM, Park HK, Kawazoe T, et al. The effect of risperidone on D-amino acid oxidase activity as a hypothesis for a novel mechanism of action in the treatment of schizophrenia. J Psychopharmacol. 2010 Jul;24(7):1055-67. PMID: 19329549.

Toohey N, Klein MT, Knight J, et al. Human 5-HT7 receptor-induced inactivation of forskolin-stimulated adenylate cyclase by risperidone, 9-OH-risperidone and other ""inactivating antagonists"". Mol Pharmacol. 2009 Sep;76(3):552-9. PMID: 19509219.

Potkin SG, Saha AR, Kujawa MJ, et al. Aripiprazole, an antipsychotic with a novel mechanism of action, and risperidone vs placebo in patients with schizophrenia and schizoaffective disorder. Arch Gen Psychiatry. 2003 Jul;60(7):681-90. PMID: 12860772.

Farde L, Nyberg S, Oxenstierna G, et al. Positron emission tomography studies on D2 and 5-HT2 receptor binding in risperidone-treated schizophrenic patients. J Clin Psychopharmacol. 1995 Feb;15(1 Suppl 1):19S-23S. PMID: 7537284.

" T "UN number: 2811     Class: 6.1     Packing Group: III

Proper shipping name: Toxic solid, organic, n.o.s. (Risperidone)"

LKT R3475 Risperidone 1 g 525 Benzisoxazole; 5-HT7 and NMDA agonist, D-amino acid oxidase inhibitor, 5-HT2A and D2 antagonist. 3-[2-[4-(6-fluoro-1,2-benzoxazol-3-yl)piperidin-1-yl]ethyl]-2-methyl-6,7,8,9-tetrahydropyrido[2,1-b]pyrimidin-4-one 106266-06-2 ≥98% 410.49 C23H27FN4O2 CC1=C(C(=O)N2CCCCC2=N1)CCN3CCC(CC3)C4=NOC5=C4C=CC(=C5)F Ambient Ambient "Kamińska K, Gołembiowska K, Rogóż Z. Effect of risperidone on the fluoxetine-induced changes in extracellular dopamine, serotonin and noradrenaline in the rat frontal cortex. Pharmacol Rep. 2013;65(5):1144-51. PMID: 24399710.

MacDowell KS, García-Bueno B, Madrigal JL, et al. Risperidone normalizes increased inflammatory parameters and restores anti-inflammatory pathways in a model of neuroinflammation. Int J Neuropsychopharmacol. 2013 Feb;16(1):121-35. PMID: 22176740.

Kozielska M, Johnson M, Pilla Reddy V, et al. Pharmacokinetic-pharmacodynamic modeling of the D2 and 5-HT (2A) receptor occupancy of risperidone and paliperidone in rats. Pharm Res. 2012 Jul;29(7):1932-48. PMID: 22437487.

Abou El-Magd RM, Park HK, Kawazoe T, et al. The effect of risperidone on D-amino acid oxidase activity as a hypothesis for a novel mechanism of action in the treatment of schizophrenia. J Psychopharmacol. 2010 Jul;24(7):1055-67. PMID: 19329549.

Toohey N, Klein MT, Knight J, et al. Human 5-HT7 receptor-induced inactivation of forskolin-stimulated adenylate cyclase by risperidone, 9-OH-risperidone and other ""inactivating antagonists"". Mol Pharmacol. 2009 Sep;76(3):552-9. PMID: 19509219.

Potkin SG, Saha AR, Kujawa MJ, et al. Aripiprazole, an antipsychotic with a novel mechanism of action, and risperidone vs placebo in patients with schizophrenia and schizoaffective disorder. Arch Gen Psychiatry. 2003 Jul;60(7):681-90. PMID: 12860772.

Farde L, Nyberg S, Oxenstierna G, et al. Positron emission tomography studies on D2 and 5-HT2 receptor binding in risperidone-treated schizophrenic patients. J Clin Psychopharmacol. 1995 Feb;15(1 Suppl 1):19S-23S. PMID: 7537284.

" T "UN number: 2811     Class: 6.1     Packing Group: III

Proper shipping name: Toxic solid, organic, n.o.s. (Risperidone)"

LKT N0123 Naftopidil 25 mg 84.3 α1-adrenergic antagonist. 57149-07-2 ≥98% 392.49 C24H28N2O3 COC1=CC=CC=C1N2CCN(CC2)CC(COC3=CC=CC4=CC=CC=C43)O Ambient Ambient "Castiglione F, Benigni F, Briganti A, et al. Naftopidil for the treatment of benign prostate hyperplasia: a systematic review. Curr Med Res Opin. 2013 Dec 18. [Epub ahead of print]. PMID: 24188134.

Yokoyama O, Aoki Y, Tsujimura A, et al. α(1)-adrenoceptor blocker naftopidil improves sleep disturbance with reduction in nocturnal urine volume. World J Urol. 2011 Apr;29(2):233-8. PMID: 20387069.

Yokoyama O, Yusup A, Oyama N, et al. Improvement of bladder storage function by alpha1-blocker depends on the suppression of C-fiber afferent activity in rats. Neurourol Urodyn. 2006;25(5):461-7. PMID: 16673377.

Alarayyed NA, Cooper MB, Prichard BN, et al. In vitro adrenaline and collagen-induced mobilization of platelet calcium and its inhibition by naftopidil, doxazosin and nifedipine. Br J Clin Pharmacol. 1997 Apr;43(4):415-20. PMID: 9146854.

" Not dangerous goods.

LKT N0123 Naftopidil 100 mg 271.8 α1-adrenergic antagonist. 57149-07-2 ≥98% 392.49 C24H28N2O3 COC1=CC=CC=C1N2CCN(CC2)CC(COC3=CC=CC4=CC=CC=C43)O Ambient Ambient "Castiglione F, Benigni F, Briganti A, et al. Naftopidil for the treatment of benign prostate hyperplasia: a systematic review. Curr Med Res Opin. 2013 Dec 18. [Epub ahead of print]. PMID: 24188134.

Yokoyama O, Aoki Y, Tsujimura A, et al. α(1)-adrenoceptor blocker naftopidil improves sleep disturbance with reduction in nocturnal urine volume. World J Urol. 2011 Apr;29(2):233-8. PMID: 20387069.

Yokoyama O, Yusup A, Oyama N, et al. Improvement of bladder storage function by alpha1-blocker depends on the suppression of C-fiber afferent activity in rats. Neurourol Urodyn. 2006;25(5):461-7. PMID: 16673377.

Alarayyed NA, Cooper MB, Prichard BN, et al. In vitro adrenaline and collagen-induced mobilization of platelet calcium and its inhibition by naftopidil, doxazosin and nifedipine. Br J Clin Pharmacol. 1997 Apr;43(4):415-20. PMID: 9146854.

" Not dangerous goods.

LKT N0123 Naftopidil 500 mg 843.9 α1-adrenergic antagonist. 57149-07-2 ≥98% 392.49 C24H28N2O3 COC1=CC=CC=C1N2CCN(CC2)CC(COC3=CC=CC4=CC=CC=C43)O Ambient Ambient "Castiglione F, Benigni F, Briganti A, et al. Naftopidil for the treatment of benign prostate hyperplasia: a systematic review. Curr Med Res Opin. 2013 Dec 18. [Epub ahead of print]. PMID: 24188134.

Yokoyama O, Aoki Y, Tsujimura A, et al. α(1)-adrenoceptor blocker naftopidil improves sleep disturbance with reduction in nocturnal urine volume. World J Urol. 2011 Apr;29(2):233-8. PMID: 20387069.

Yokoyama O, Yusup A, Oyama N, et al. Improvement of bladder storage function by alpha1-blocker depends on the suppression of C-fiber afferent activity in rats. Neurourol Urodyn. 2006;25(5):461-7. PMID: 16673377.

Alarayyed NA, Cooper MB, Prichard BN, et al. In vitro adrenaline and collagen-induced mobilization of platelet calcium and its inhibition by naftopidil, doxazosin and nifedipine. Br J Clin Pharmacol. 1997 Apr;43(4):415-20. PMID: 9146854.

" Not dangerous goods.

LKT N0160 NAP Peptide 0.5 mg 37.5 Octapeptide derived from activity-dependent neuroprotective protein (ADNP). Davunetide 211439-12-2 ≥95% 824.94 C36H60N10O12 "CCC(C)C(C(=O)N1CCCC1C(=O)NC(CCC(=O)N)C(=O)O)NC(=O)C(CO)NC(=O)C(C(C)C)NC(=O)C2CCCN2C(=O)C(C)NC(=O)C(CC(=O)N)N

" Ambient -20°C "Scuderi S, D'Amico AG, Castorina A, et al. Davunetide (NAP) Protects the Retina Against Early Diabetic Injury by Reducing Apoptotic Death. J Mol Neurosci. 2014 Feb 2. [Epub ahead of print]. PMID: 24488575.

Jouroukhin Y, Ostritsky R, Assaf Y, et al. NAP (davunetide) modifies disease progression in a mouse model of severe neurodegeneration: protection against impairments in axonal transport. Neurobiol Dis. 2013 Aug;56:79-94. PMID: 23631872.

Gold M, Lorenzl S, Stewart AJ, et al. Critical appraisal of the role of davunetide in the treatment of progressive supranuclear palsy. Neuropsychiatr Dis Treat. 2012;8:85-93. PMID: 22347799.

Sharma NK, Sethy NK, Meena RN, et al. Activity-dependent neuroprotective protein (ADNP)-derived peptide (NAP) ameliorates hypobaric hypoxia induced oxidative stress in rat brain. Peptides. 2011 Jun;32(6):1217-24. PMID: 21453737.

Merenlender-Wagner A, Pikman R, Giladi E, et al. NAP (davunetide) enhances cognitive behavior in the STOP heterozygous mouse--a microtubule-deficient model of schizophrenia. Peptides. 2010 Jul;31(7):1368-73. PMID: 20417241.

" Not dangerous goods.

LKT N0160 NAP Peptide 1 mg 63.8 Octapeptide derived from activity-dependent neuroprotective protein (ADNP). Davunetide 211439-12-2 ≥95% 824.94 C36H60N10O12 "CCC(C)C(C(=O)N1CCCC1C(=O)NC(CCC(=O)N)C(=O)O)NC(=O)C(CO)NC(=O)C(C(C)C)NC(=O)C2CCCN2C(=O)C(C)NC(=O)C(CC(=O)N)N

" Ambient -20°C "Scuderi S, D'Amico AG, Castorina A, et al. Davunetide (NAP) Protects the Retina Against Early Diabetic Injury by Reducing Apoptotic Death. J Mol Neurosci. 2014 Feb 2. [Epub ahead of print]. PMID: 24488575.

Jouroukhin Y, Ostritsky R, Assaf Y, et al. NAP (davunetide) modifies disease progression in a mouse model of severe neurodegeneration: protection against impairments in axonal transport. Neurobiol Dis. 2013 Aug;56:79-94. PMID: 23631872.

Gold M, Lorenzl S, Stewart AJ, et al. Critical appraisal of the role of davunetide in the treatment of progressive supranuclear palsy. Neuropsychiatr Dis Treat. 2012;8:85-93. PMID: 22347799.

Sharma NK, Sethy NK, Meena RN, et al. Activity-dependent neuroprotective protein (ADNP)-derived peptide (NAP) ameliorates hypobaric hypoxia induced oxidative stress in rat brain. Peptides. 2011 Jun;32(6):1217-24. PMID: 21453737.

Merenlender-Wagner A, Pikman R, Giladi E, et al. NAP (davunetide) enhances cognitive behavior in the STOP heterozygous mouse--a microtubule-deficient model of schizophrenia. Peptides. 2010 Jul;31(7):1368-73. PMID: 20417241.

" Not dangerous goods.

LKT N0160 NAP Peptide 2.5 mg 112.5 Octapeptide derived from activity-dependent neuroprotective protein (ADNP). Davunetide 211439-12-2 ≥95% 824.94 C36H60N10O12 "CCC(C)C(C(=O)N1CCCC1C(=O)NC(CCC(=O)N)C(=O)O)NC(=O)C(CO)NC(=O)C(C(C)C)NC(=O)C2CCCN2C(=O)C(C)NC(=O)C(CC(=O)N)N

" Ambient -20°C "Scuderi S, D'Amico AG, Castorina A, et al. Davunetide (NAP) Protects the Retina Against Early Diabetic Injury by Reducing Apoptotic Death. J Mol Neurosci. 2014 Feb 2. [Epub ahead of print]. PMID: 24488575.

Jouroukhin Y, Ostritsky R, Assaf Y, et al. NAP (davunetide) modifies disease progression in a mouse model of severe neurodegeneration: protection against impairments in axonal transport. Neurobiol Dis. 2013 Aug;56:79-94. PMID: 23631872.

Gold M, Lorenzl S, Stewart AJ, et al. Critical appraisal of the role of davunetide in the treatment of progressive supranuclear palsy. Neuropsychiatr Dis Treat. 2012;8:85-93. PMID: 22347799.

Sharma NK, Sethy NK, Meena RN, et al. Activity-dependent neuroprotective protein (ADNP)-derived peptide (NAP) ameliorates hypobaric hypoxia induced oxidative stress in rat brain. Peptides. 2011 Jun;32(6):1217-24. PMID: 21453737.

Merenlender-Wagner A, Pikman R, Giladi E, et al. NAP (davunetide) enhances cognitive behavior in the STOP heterozygous mouse--a microtubule-deficient model of schizophrenia. Peptides. 2010 Jul;31(7):1368-73. PMID: 20417241.

" Not dangerous goods.

LKT N0161 β-Naphthoflavone 1 g 82.2 AhR agonist. 5,6-Benzoflavone 6051-87-2 ≥98% 272.3 C19H12O2 C1=CC=C(C=C1)C2=CC(=O)C3=C(O2)C=CC4=CC=CC=C43 Ambient Ambient Slightly soluble in DMSO. "Wang C, Xu CX, Bu Y, et al. Beta-naphthoflavone (DB06732) mediates estrogen receptor-positive breast cancer cell cycle arrest through AhR-dependent regulation of PI3K/AKT and MAPK/ERK signaling. Carcinogenesis. 2014 Mar;35(3):703-13. PMID: 24163404.

Tilton SC, Givan SA, Pereira CB, et al. Toxicogenomic profiling of the hepatic tumor promoters indole-3-carbinol, 17beta-estradiol and beta-naphthoflavone in rainbow trout. Toxicol Sci. 2006 Mar;90(1):61-72. PMID: 16192472.

Izzotti A, Bagnasco M, Cartiglia C, et al. Modulation of multigene expression and proteome profiles by chemopreventive agents. Mutat Res. 2005 Dec 11;591(1-2):212-23. PMID: 16083920.

" Xn Not dangerous goods.

LKT N0161 β-Naphthoflavone 5 g 261.6 AhR agonist. 5,6-Benzoflavone 6051-87-2 ≥98% 272.3 C19H12O2 C1=CC=C(C=C1)C2=CC(=O)C3=C(O2)C=CC4=CC=CC=C43 Ambient Ambient Slightly soluble in DMSO. "Wang C, Xu CX, Bu Y, et al. Beta-naphthoflavone (DB06732) mediates estrogen receptor-positive breast cancer cell cycle arrest through AhR-dependent regulation of PI3K/AKT and MAPK/ERK signaling. Carcinogenesis. 2014 Mar;35(3):703-13. PMID: 24163404.

Tilton SC, Givan SA, Pereira CB, et al. Toxicogenomic profiling of the hepatic tumor promoters indole-3-carbinol, 17beta-estradiol and beta-naphthoflavone in rainbow trout. Toxicol Sci. 2006 Mar;90(1):61-72. PMID: 16192472.

Izzotti A, Bagnasco M, Cartiglia C, et al. Modulation of multigene expression and proteome profiles by chemopreventive agents. Mutat Res. 2005 Dec 11;591(1-2):212-23. PMID: 16083920.

" Xn Not dangerous goods.

LKT N0163 2-(1,8-Naphthyridin-2-yl)phenol 500 mg 148.4 Naphthalene; indirect STAT1 agonist. 65182-56-1 ≥98% 222.24 C14H10N2O C1=CC(=C2C=CC3=C(N2)N=CC=C3)C(=O)C=C1 Ambient -20°C Lynch RA, Etchin J, Battle TE, et al. A small-molecule enhancer of signal transducer and activator of transcription 1 transcriptional activity accentuates the antiproliferative effects of IFN-gamma in human cancer cells. Cancer Res. 2007 Feb 1;67(3):1254-61. PMID: 17283162. Not dangerous goods.

LKT N0163 2-(1,8-Naphthyridin-2-yl)phenol 1 g 247.5 Naphthalene; indirect STAT1 agonist. 65182-56-1 ≥98% 222.24 C14H10N2O C1=CC(=C2C=CC3=C(N2)N=CC=C3)C(=O)C=C1 Ambient -20°C Lynch RA, Etchin J, Battle TE, et al. A small-molecule enhancer of signal transducer and activator of transcription 1 transcriptional activity accentuates the antiproliferative effects of IFN-gamma in human cancer cells. Cancer Res. 2007 Feb 1;67(3):1254-61. PMID: 17283162. Not dangerous goods.

LKT N0163 2-(1,8-Naphthyridin-2-yl)phenol 5 g 1031.4 Naphthalene; indirect STAT1 agonist. 65182-56-1 ≥98% 222.24 C14H10N2O C1=CC(=C2C=CC3=C(N2)N=CC=C3)C(=O)C=C1 Ambient -20°C Lynch RA, Etchin J, Battle TE, et al. A small-molecule enhancer of signal transducer and activator of transcription 1 transcriptional activity accentuates the antiproliferative effects of IFN-gamma in human cancer cells. Cancer Res. 2007 Feb 1;67(3):1254-61. PMID: 17283162. Not dangerous goods.

LKT R3374 Risedronic Acid 100 mg 95.1 Bisphosphonate; inhibits transfer of farnesyl pyrophosphate. [1-Hydroxy-2-(3-pyridinyl)ethylidene]bisphosphonic acid Risedronate 105462-24-6 ≥97% 283.11 C7H11NO7P2 C1=CC(=CN=C1)CC(O)(P(=O)(O)O)P(=O)(O)O Ambient Ambient "Jin J, Wang L, Wang XK, et al. Risedronate inhibits bone marrow mesenchymal stem cell adipogenesis and switches RANKL/OPG ratio to impair osteoclast differentiation. J Surg Res. 2013 Mar;180(1):e21-9. PMID: 22487394.

Jordão FM, Saito AY, Miguel DC, et al. In vitro and in vivo antiplasmodial activities of risedronate and its interference with protein prenylation in Plasmodium falciparum. Antimicrob Agents Chemother. 2011 May;55(5):2026-31. PMID: 21357292.

Carvalho AP, Bezerra MM, Girão VC, et al. Anti-inflammatory and anti-nociceptive activity of risedronate in experimental pain models in rats and mice. Clin Exp Pharmacol Physiol. 2006 Jul;33(7):601-6. PMID: 16789926.

" Not dangerous goods.

LKT N0205 Nabumetone 5 g 86.4 1-Naphthalenacetic acid derivative, NSAID; COX-2 inhibitor. 4-(6-Methoxy-2-naphthalenyl)-2-butanone Arthaxan; Balmox; Consolan; Nabuser; Relafen; Relifen 42924-53-8 ≥98% 228.29 C15H16O2 CC(=O)CCC1=CC2=C(C=C1)C=C(C=C2)OC Ambient Ambient Soluble in DMSO. Insoluble in water. "Paul S, Das N, Ghosh S. The effects of aceclofenac and nabumetone in osteoarthritis. JNMA J Nepal Med Assoc. 2009 Apr-Jun;48(174):121-5. PMID: 20387351.

Roy HK, Karoski WJ, Ratashak A, et al. Chemoprevention of intestinal tumorigenesis by nabumetone: induction of apoptosis and Bcl-2 downregulation. Br J Cancer. 2001 May 18;84(10):1412-6. PMID: 11355956.

" None Not dangerous goods.

LKT N0205 Nabumetone 25 g 282.3 1-Naphthalenacetic acid derivative, NSAID; COX-2 inhibitor. 4-(6-Methoxy-2-naphthalenyl)-2-butanone Arthaxan; Balmox; Consolan; Nabuser; Relafen; Relifen 42924-53-8 ≥98% 228.29 C15H16O2 CC(=O)CCC1=CC2=C(C=C1)C=C(C=C2)OC Ambient Ambient Soluble in DMSO. Insoluble in water. "Paul S, Das N, Ghosh S. The effects of aceclofenac and nabumetone in osteoarthritis. JNMA J Nepal Med Assoc. 2009 Apr-Jun;48(174):121-5. PMID: 20387351.

Roy HK, Karoski WJ, Ratashak A, et al. Chemoprevention of intestinal tumorigenesis by nabumetone: induction of apoptosis and Bcl-2 downregulation. Br J Cancer. 2001 May 18;84(10):1412-6. PMID: 11355956.

" None Not dangerous goods.

LKT N0212 Nedaplatin 10 mg 149.5 Pt-based DNA cross-linker. 95734-82-0 ≥98% 303.18 C2H8N2O3Pt C(C(=O)O)O.[NH2-].[NH2-].[Pt+2] Ambient -20°C "Yuan G, Wu L, Huang M, et al. A phase II study of concurrent chemo-radiotherapy with weekly nedaplatin in advanced squamous cell carcinoma of the uterine cervix. Radiat Oncol. 2014 Feb 18;9:55. PMID: 24533532.

Ali I, Wani WA, Saleem K, et al. Platinum compounds: a hope for future cancer chemotherapy. Anticancer Agents Med Chem. 2013 Feb;13(2):296-306. PMID: 22583420.

Poklar N, Pilch DS, Lippard SJ, et al. Influence of cisplatin intrastrand crosslinking on the conformation, thermal stability, and energetics of a 20-mer DNA duplex. Proc Natl Acad Sci U S A. 1996 Jul 23;93(15):7606-11. PMID: 8755522.

" "UN number: 2811 Class: 6.1 Packing group: II

Proper shipping name: Toxic solid, organic, n.o.s. (Nedaplatin)

Marine pollutant: No Poison Inhalation Hazard: No"

LKT N0212 Nedaplatin 25 mg 285.4 Pt-based DNA cross-linker. 95734-82-0 ≥98% 303.18 C2H8N2O3Pt C(C(=O)O)O.[NH2-].[NH2-].[Pt+2] Ambient -20°C "Yuan G, Wu L, Huang M, et al. A phase II study of concurrent chemo-radiotherapy with weekly nedaplatin in advanced squamous cell carcinoma of the uterine cervix. Radiat Oncol. 2014 Feb 18;9:55. PMID: 24533532.

Ali I, Wani WA, Saleem K, et al. Platinum compounds: a hope for future cancer chemotherapy. Anticancer Agents Med Chem. 2013 Feb;13(2):296-306. PMID: 22583420.

Poklar N, Pilch DS, Lippard SJ, et al. Influence of cisplatin intrastrand crosslinking on the conformation, thermal stability, and energetics of a 20-mer DNA duplex. Proc Natl Acad Sci U S A. 1996 Jul 23;93(15):7606-11. PMID: 8755522.

" "UN number: 2811 Class: 6.1 Packing group: II

Proper shipping name: Toxic solid, organic, n.o.s. (Nedaplatin)

Marine pollutant: No Poison Inhalation Hazard: No"

LKT N0212 Nedaplatin 50 mg 529.9 Pt-based DNA cross-linker. 95734-82-0 ≥98% 303.18 C2H8N2O3Pt C(C(=O)O)O.[NH2-].[NH2-].[Pt+2] Ambient -20°C "Yuan G, Wu L, Huang M, et al. A phase II study of concurrent chemo-radiotherapy with weekly nedaplatin in advanced squamous cell carcinoma of the uterine cervix. Radiat Oncol. 2014 Feb 18;9:55. PMID: 24533532.

Ali I, Wani WA, Saleem K, et al. Platinum compounds: a hope for future cancer chemotherapy. Anticancer Agents Med Chem. 2013 Feb;13(2):296-306. PMID: 22583420.

Poklar N, Pilch DS, Lippard SJ, et al. Influence of cisplatin intrastrand crosslinking on the conformation, thermal stability, and energetics of a 20-mer DNA duplex. Proc Natl Acad Sci U S A. 1996 Jul 23;93(15):7606-11. PMID: 8755522.

" "UN number: 2811 Class: 6.1 Packing group: II

Proper shipping name: Toxic solid, organic, n.o.s. (Nedaplatin)

Marine pollutant: No Poison Inhalation Hazard: No"

LKT R3373 Risedronate Sodium Hydrate 100 mg 136 Bisphosphonate; inhibits transfer of farnesyl pyrophosphate. [1-Hydroxy-2-(3-pyridinyl)ethylidene]bisphosphonic acid monosodium salt Risedronic acid monosodium salt; Actonel; Optinate 115436-72-1 ≥98% 350.13 C7H10NO7P2Na 2.5H2O C1=CC(=CN=C1)CC(O)(P(=O)(O)O)P(=O)(O)[O-].[Na+] Ambient Ambient Soluble in water. Insoluble in organic solvents. "Lems WF, den Heijer M. Established and forthcoming drugs for the treatment of osteoporosis. Neth J Med. 2013 May;71(4):188-93. PMID: 23723112.

Jin J, Wang L, Wang XK, et al. Risedronate inhibits bone marrow mesenchymal stem cell adipogenesis and switches RANKL/OPG ratio to impair osteoclast differentiation. J Surg Res. 2013 Mar;180(1):e21-9. PMID: 22487394.

Matsumoto T, Nagase Y, Iwasawa M, et al. Distinguishing the proapoptotic and antiresorptive functions of risedronate in murine osteoclasts: role of the Akt pathway and the ERK/Bim axis. Arthritis Rheum. 2011 Dec;63(12):3908-17. PMID: 21898348.

Jordão FM, Saito AY, Miguel DC, et al. In vitro and in vivo antiplasmodial activities of risedronate and its interference with protein prenylation in Plasmodium falciparum. Antimicrob Agents Chemother. 2011 May;55(5):2026-31. PMID: 21357292.

" Xi Not dangerous goods.

LKT N0262 Naphazoline Hydrochloride 25 g 54.4 α1-adrenergic agonist. 4,5-Dihydro-2-(1-naphthalenylmethyl)-1H-imidazole hydrochloride Ak-Con; Clera; Naphcon; Rhinantin; Sanorin; Strictylon 550-99-2 ≥97% 246.74 C14H14N2 HCl C1CN=C(N1)CC2=CC=CC3=CC=CC=C32.Cl Ambient 4°C Freely soluble in water and alcohol. "Fuchs R, Schraml E, Leitinger G, et al. α1-Adrenergic drugs modulate differentiation and cell death of human erythroleukemia cells through non adrenergic mechanism. Exp Cell Res. 2011 Oct 1;317(16):2239-51. PMID: 21781962.

Nagane Y, Utsugisawa K, Suzuki S, et al. Topical naphazoline in the treatment of myasthenic blepharoptosis. Muscle Nerve. 2011 Jul;44(1):41-4. PMID: 21491460.

Rikimaru T. Therapeutic management of endobronchial tuberculosis. Expert Opin Pharmacother. 2004 Jul;5(7):1463-70. PMID: 15212597.

" Xn, T "UN number: 2811     Class: 6.1     Packing Group: II

Proper shipping name: Toxic solid, organic, n.o.s. (Naphazoline hydrochloride)

Marine pollutant: No"

LKT N0262 Naphazoline Hydrochloride 100 g 183.4 α1-adrenergic agonist. 4,5-Dihydro-2-(1-naphthalenylmethyl)-1H-imidazole hydrochloride Ak-Con; Clera; Naphcon; Rhinantin; Sanorin; Strictylon 550-99-2 ≥97% 246.74 C14H14N2 HCl C1CN=C(N1)CC2=CC=CC3=CC=CC=C32.Cl Ambient 4°C Freely soluble in water and alcohol. "Fuchs R, Schraml E, Leitinger G, et al. α1-Adrenergic drugs modulate differentiation and cell death of human erythroleukemia cells through non adrenergic mechanism. Exp Cell Res. 2011 Oct 1;317(16):2239-51. PMID: 21781962.

Nagane Y, Utsugisawa K, Suzuki S, et al. Topical naphazoline in the treatment of myasthenic blepharoptosis. Muscle Nerve. 2011 Jul;44(1):41-4. PMID: 21491460.

Rikimaru T. Therapeutic management of endobronchial tuberculosis. Expert Opin Pharmacother. 2004 Jul;5(7):1463-70. PMID: 15212597.

" Xn, T "UN number: 2811     Class: 6.1     Packing Group: II

Proper shipping name: Toxic solid, organic, n.o.s. (Naphazoline hydrochloride)

Marine pollutant: No"

LKT R3347 Riluzole 25 mg 75 Benzothiazole; TRPC5 agonist, PTR1 inhibitor, voltage-gated Na+ channel blocker, GLT-1 modulator. 6-(trifluoromethoxy)-1,3-benzothiazol-2-amine Rilutek 1744-22-5 ≥98% 234.19 C8H5F3N2OS C1=CC2=C(C=C1OC(F)(F)F)SC(=N2)N Ambient Ambient "Richter JM, Schaefer M, Hill K. Riluzole activates TRPC5 channels independently of PLC activity. Br J Pharmacol. 2014 Jan;171(1):158-70. PMID: 24117252.

Daniel B, Green O, Viskind O, et al. Riluzole increases the rate of glucose transport in L6 myotubes and NSC-34 motor neuron-like cells via AMPK pathway activation. Amyotroph Lateral Scler Frontotemporal Degener. 2013 Sep;14(5-6):434-43. PMID: 23834207.

Guerrieri D, Ferrari S, Costi MP, et al. Biochemical effects of riluzole on Leishmania parasites. Exp Parasitol. 2013 Mar;133(3):250-4. PMID: 23206955.

Sugiyama A, Saitoh A, Iwai T, et al. Riluzole produces distinct anxiolytic-like effects in rats without the adverse effects associated with benzodiazepines. Neuropharmacology. 2012 Jun;62(8):2489-98. PMID: 22377384.

Bellingham MC. A review of the neural mechanisms of action and clinical efficiency of riluzole in treating amyotrophic lateral sclerosis: what have we learned in the last decade? CNS Neurosci Ther. 2011 Feb;17(1):4-31. PMID: 20236142.

Hama A, Sagen J. Antinociceptive effect of riluzole in rats with neuropathic spinal cord injury pain. J Neurotrauma. 2011 Jan;28(1):127-34. PMID: 20954888.

" T "UN number: 2811     Class:  6.1     Packing group:  III

Proper shipping name:  Toxic solids, organic, n.o.s.  (Riluzole)

Marine pollutant:  No     Poison inhalation hazard:  No"

LKT R3347 Riluzole 250 mg 562.5 Benzothiazole; TRPC5 agonist, PTR1 inhibitor, voltage-gated Na+ channel blocker, GLT-1 modulator. 6-(trifluoromethoxy)-1,3-benzothiazol-2-amine Rilutek 1744-22-5 ≥98% 234.19 C8H5F3N2OS C1=CC2=C(C=C1OC(F)(F)F)SC(=N2)N Ambient Ambient "Richter JM, Schaefer M, Hill K. Riluzole activates TRPC5 channels independently of PLC activity. Br J Pharmacol. 2014 Jan;171(1):158-70. PMID: 24117252.

Daniel B, Green O, Viskind O, et al. Riluzole increases the rate of glucose transport in L6 myotubes and NSC-34 motor neuron-like cells via AMPK pathway activation. Amyotroph Lateral Scler Frontotemporal Degener. 2013 Sep;14(5-6):434-43. PMID: 23834207.

Guerrieri D, Ferrari S, Costi MP, et al. Biochemical effects of riluzole on Leishmania parasites. Exp Parasitol. 2013 Mar;133(3):250-4. PMID: 23206955.

Sugiyama A, Saitoh A, Iwai T, et al. Riluzole produces distinct anxiolytic-like effects in rats without the adverse effects associated with benzodiazepines. Neuropharmacology. 2012 Jun;62(8):2489-98. PMID: 22377384.

Bellingham MC. A review of the neural mechanisms of action and clinical efficiency of riluzole in treating amyotrophic lateral sclerosis: what have we learned in the last decade? CNS Neurosci Ther. 2011 Feb;17(1):4-31. PMID: 20236142.

Hama A, Sagen J. Antinociceptive effect of riluzole in rats with neuropathic spinal cord injury pain. J Neurotrauma. 2011 Jan;28(1):127-34. PMID: 20954888.

" T "UN number: 2811     Class:  6.1     Packing group:  III

Proper shipping name:  Toxic solids, organic, n.o.s.  (Riluzole)

Marine pollutant:  No     Poison inhalation hazard:  No"

LKT R3347 Riluzole 500 mg 900.1 Benzothiazole; TRPC5 agonist, PTR1 inhibitor, voltage-gated Na+ channel blocker, GLT-1 modulator. 6-(trifluoromethoxy)-1,3-benzothiazol-2-amine Rilutek 1744-22-5 ≥98% 234.19 C8H5F3N2OS C1=CC2=C(C=C1OC(F)(F)F)SC(=N2)N Ambient Ambient "Richter JM, Schaefer M, Hill K. Riluzole activates TRPC5 channels independently of PLC activity. Br J Pharmacol. 2014 Jan;171(1):158-70. PMID: 24117252.

Daniel B, Green O, Viskind O, et al. Riluzole increases the rate of glucose transport in L6 myotubes and NSC-34 motor neuron-like cells via AMPK pathway activation. Amyotroph Lateral Scler Frontotemporal Degener. 2013 Sep;14(5-6):434-43. PMID: 23834207.

Guerrieri D, Ferrari S, Costi MP, et al. Biochemical effects of riluzole on Leishmania parasites. Exp Parasitol. 2013 Mar;133(3):250-4. PMID: 23206955.

Sugiyama A, Saitoh A, Iwai T, et al. Riluzole produces distinct anxiolytic-like effects in rats without the adverse effects associated with benzodiazepines. Neuropharmacology. 2012 Jun;62(8):2489-98. PMID: 22377384.

Bellingham MC. A review of the neural mechanisms of action and clinical efficiency of riluzole in treating amyotrophic lateral sclerosis: what have we learned in the last decade? CNS Neurosci Ther. 2011 Feb;17(1):4-31. PMID: 20236142.

Hama A, Sagen J. Antinociceptive effect of riluzole in rats with neuropathic spinal cord injury pain. J Neurotrauma. 2011 Jan;28(1):127-34. PMID: 20954888.

" T "UN number: 2811     Class:  6.1     Packing group:  III

Proper shipping name:  Toxic solids, organic, n.o.s.  (Riluzole)

Marine pollutant:  No     Poison inhalation hazard:  No"

LKT N0263 Naphazoline Nitrate 10 g 33.9 α1-adrenergic agonist. 4,5-Dihydro-2-(1-naphthalenylmethyl)-1H-imidazole nitrate "Imidazyl; Naftizin; Rhinon; Sanorin

" 5144-52-5 ≥97% 273.29 C14H14N2 HNO3 C1CN=C([NH2+]1)CC2=CC=CC3=CC=CC=C32.[N+](=O)([O-])[O-] Slightly soluble in water. Soluble in alcohol. Insoluble in ether. Ambient 4°C "Fuchs R, Schraml E, Leitinger G, et al. α1-Adrenergic drugs modulate differentiation and cell death of human erythroleukemia cells through non adrenergic mechanism. Exp Cell Res. 2011 Oct 1;317(16):2239-51. PMID: 21781962.

Nagane Y, Utsugisawa K, Suzuki S, et al. Topical naphazoline in the treatment of myasthenic blepharoptosis. Muscle Nerve. 2011 Jul;44(1):41-4. PMID: 21491460.

Rikimaru T. Therapeutic management of endobronchial tuberculosis. Expert Opin Pharmacother. 2004 Jul;5(7):1463-70. PMID: 15212597.

" Xn Not dangerous goods.

LKT N0263 Naphazoline Nitrate 25 g 58.9 α1-adrenergic agonist. 4,5-Dihydro-2-(1-naphthalenylmethyl)-1H-imidazole nitrate "Imidazyl; Naftizin; Rhinon; Sanorin

" 5144-52-5 ≥97% 273.29 C14H14N2 HNO3 C1CN=C([NH2+]1)CC2=CC=CC3=CC=CC=C32.[N+](=O)([O-])[O-] Slightly soluble in water. Soluble in alcohol. Insoluble in ether. Ambient 4°C "Fuchs R, Schraml E, Leitinger G, et al. α1-Adrenergic drugs modulate differentiation and cell death of human erythroleukemia cells through non adrenergic mechanism. Exp Cell Res. 2011 Oct 1;317(16):2239-51. PMID: 21781962.

Nagane Y, Utsugisawa K, Suzuki S, et al. Topical naphazoline in the treatment of myasthenic blepharoptosis. Muscle Nerve. 2011 Jul;44(1):41-4. PMID: 21491460.

Rikimaru T. Therapeutic management of endobronchial tuberculosis. Expert Opin Pharmacother. 2004 Jul;5(7):1463-70. PMID: 15212597.

" Xn Not dangerous goods.

LKT N0263 Naphazoline Nitrate 100 g 185 α1-adrenergic agonist. 4,5-Dihydro-2-(1-naphthalenylmethyl)-1H-imidazole nitrate "Imidazyl; Naftizin; Rhinon; Sanorin

" 5144-52-5 ≥97% 273.29 C14H14N2 HNO3 C1CN=C([NH2+]1)CC2=CC=CC3=CC=CC=C32.[N+](=O)([O-])[O-] Slightly soluble in water. Soluble in alcohol. Insoluble in ether. Ambient 4°C "Fuchs R, Schraml E, Leitinger G, et al. α1-Adrenergic drugs modulate differentiation and cell death of human erythroleukemia cells through non adrenergic mechanism. Exp Cell Res. 2011 Oct 1;317(16):2239-51. PMID: 21781962.

Nagane Y, Utsugisawa K, Suzuki S, et al. Topical naphazoline in the treatment of myasthenic blepharoptosis. Muscle Nerve. 2011 Jul;44(1):41-4. PMID: 21491460.

Rikimaru T. Therapeutic management of endobronchial tuberculosis. Expert Opin Pharmacother. 2004 Jul;5(7):1463-70. PMID: 15212597.

" Xn Not dangerous goods.

LKT R3321 Rifaimin 500 mg 88.3 Rifampicin derivative; DNA-dependent RNA polymerase inhibitor. [2S-(2R*,16Z,18E,20R*,21R*,22S*,23S*,24S*,25R*,26S*,27R*,28E)]-25-(Acetyloxy)-5,6,21,23-tetrahydroxy-27-methoxy-2,4,11,16,20,22,24,26-octamethyl-2,7- [epoxypentadeca(1,11,13)trienimino]-benzofuro[4,5-e]- pyridol[1,2-a]benzimidazole-1,15(2H)-dione Rifacol; XIFAAN; Fatroximin; Normix; Rifacol 80621-81-4 ≥98% 785.88 C43H51N3O11 CC1C=CC=C(C(=O)NC2=C(C3=C(C4=C(C(=C3O)C)OC(C4=O)(OC=CC(C(C(C(C(C(C1O)C)O)C)OC(=O)C)C)OC)C)C5=C2N6C=CC(=CC6=N5)C)O)C Ambient 4°C Soluble in alcohols, ethyl acetate, chloroform or toluene. "Huhulescu S, Sagel U, Fiedler A, et al. Rifaimin disc diffusion test for in vitro susceptibility testing of Clostridium difficile. J Med Microbiol. 2011 Aug;60(Pt 8):1206-12. PMID: 21292853.

Majewski M, McCallum RW. Results of small intestinal bacterial overgrowth testing in irritable bowel syndrome patients: clinical profiles and effects of antibiotic trial. Adv Med Sci. 2007;52:139-42. PMID: 18217406.

" None Not dangerous goods.

LKT R3321 Rifximin 1 g 128.6 Rifampicin derivative; DNA-dependent RNA polymerase inhibitor. [2S-(2R*,16Z,18E,20R*,21R*,22S*,23S*,24S*,25R*,26S*,27R*,28E)]-25-(Acetyloxy)-5,6,21,23-tetrahydroxy-27-methoxy-2,4,11,16,20,22,24,26-octamethyl-2,7- [epoxypentadeca(1,11,13)trienimino]-benzofuro[4,5-e]- pyridol[1,2-a]benzimidazole-1,15(2H)-dione Rifacol; XIFXAN; Fatroximin; Normix; Rifacol 80621-81-4 ≥98% 785.88 C43H51N3O11 CC1C=CC=C(C(=O)NC2=C(C3=C(C4=C(C(=C3O)C)OC(C4=O)(OC=CC(C(C(C(C(C(C1O)C)O)C)OC(=O)C)C)OC)C)C5=C2N6C=CC(=CC6=N5)C)O)C Ambient 4°C Soluble in alcohols, ethyl acetate, chloroform or toluene. "Huhulescu S, Sagel U, Fiedler A, et al. Riaximin disc diffusion test for in vitro susceptibility testing of Clostridium difficile. J Med Microbiol. 2011 Aug;60(Pt 8):1206-12. PMID: 21292853.

Majewski M, McCallum RW. Results of small intestinal bacterial overgrowth testing in irritable bowel syndrome patients: clinical profiles and effects of antibiotic trial. Adv Med Sci. 2007;52:139-42. PMID: 18217406.

" None Not dangerous goods.

LKT R3321 Riaximin 5 g 515.7 Rifampicin derivative; DNA-dependent RNA polymerase inhibitor. [2S-(2R*,16Z,18E,20R*,21R*,22S*,23S*,24S*,25R*,26S*,27R*,28E)]-25-(Acetyloxy)-5,6,21,23-tetrahydroxy-27-methoxy-2,4,11,16,20,22,24,26-octamethyl-2,7- [epoxypentadeca(1,11,13)trienimino]-benzofuro[4,5-e]- pyridol[1,2-a]benzimidazole-1,15(2H)-dione Rifacol; XIFXAN; Fatroximin; Normix; Rifacol 80621-81-4 ≥98% 785.88 C43H51N3O11 CC1C=CC=C(C(=O)NC2=C(C3=C(C4=C(C(=C3O)C)OC(C4=O)(OC=CC(C(C(C(C(C(C1O)C)O)C)OC(=O)C)C)OC)C)C5=C2N6C=CC(=CC6=N5)C)O)C Ambient 4°C Soluble in alcohols, ethyl acetate, chloroform or toluene. "Huhulescu S, Sagel U, Fiedler A, et al. Rifximin disc diffusion test for in vitro susceptibility testing of Clostridium difficile. J Med Microbiol. 2011 Aug;60(Pt 8):1206-12. PMID: 21292853.

Majewski M, McCallum RW. Results of small intestinal bacterial overgrowth testing in irritable bowel syndrome patients: clinical profiles and effects of antibiotic trial. Adv Med Sci. 2007;52:139-42. PMID: 18217406.

" None Not dangerous goods.

LKT R3312 Ridaifen A Dihydrochloride 25 mg 100.5 Tamoxifen derivative; potential proteasome inhibitor. ≥98% 531.56 C30H38N2O22HCl Ambient Ambient "Hasegawa M, Yasuda Y, Tanaka M, et al. A novel tamoxifen derivative, ridaifen-F, is a nonpeptidic small-molecule proteasome inhibitor. Eur J Med Chem. 2013 Nov 16;71C:290-305. PMID: 24321833.

Guo WZ, Shiina I, Wang Y, et al. Ridaifen-SB8, a novel tamoxifen derivative, induces apoptosis via reactive oxygen species-dependent signaling pathway. Biochem Pharmacol. 2013 Nov 1;86(9):1272-84. PMID: 23973528.

Nagahara Y, Shiina I, Nakata K, et al. Induction of mitochondria-involved apoptosis in estrogen receptor-negative cells by a novel tamoxifen derivative, ridaifen-B. Cancer Sci. 2008 Mar;99(3):608-14. PMID: 18167132.

" Not dangerous goods.

LKT R3312 Ridaifen A Dihydrochloride 100 mg 293.1 Tamoxifen derivative; potential proteasome inhibitor. ≥98% 531.56 C30H38N2O22HCl Ambient Ambient "Hasegawa M, Yasuda Y, Tanaka M, et al. A novel tamoxifen derivative, ridaifen-F, is a nonpeptidic small-molecule proteasome inhibitor. Eur J Med Chem. 2013 Nov 16;71C:290-305. PMID: 24321833.

Guo WZ, Shiina I, Wang Y, et al. Ridaifen-SB8, a novel tamoxifen derivative, induces apoptosis via reactive oxygen species-dependent signaling pathway. Biochem Pharmacol. 2013 Nov 1;86(9):1272-84. PMID: 23973528.

Nagahara Y, Shiina I, Nakata K, et al. Induction of mitochondria-involved apoptosis in estrogen receptor-negative cells by a novel tamoxifen derivative, ridaifen-B. Cancer Sci. 2008 Mar;99(3):608-14. PMID: 18167132.

" Not dangerous goods.

LKT R3312 Ridaifen A Dihydrochloride 250 mg 627.8 Tamoxifen derivative; potential proteasome inhibitor. ≥98% 531.56 C30H38N2O22HCl Ambient Ambient "Hasegawa M, Yasuda Y, Tanaka M, et al. A novel tamoxifen derivative, ridaifen-F, is a nonpeptidic small-molecule proteasome inhibitor. Eur J Med Chem. 2013 Nov 16;71C:290-305. PMID: 24321833.

Guo WZ, Shiina I, Wang Y, et al. Ridaifen-SB8, a novel tamoxifen derivative, induces apoptosis via reactive oxygen species-dependent signaling pathway. Biochem Pharmacol. 2013 Nov 1;86(9):1272-84. PMID: 23973528.

Nagahara Y, Shiina I, Nakata K, et al. Induction of mitochondria-involved apoptosis in estrogen receptor-negative cells by a novel tamoxifen derivative, ridaifen-B. Cancer Sci. 2008 Mar;99(3):608-14. PMID: 18167132.

" Not dangerous goods.

LKT N1721 Nefiracetam 100 mg 84.3 Pyrrolidone; NMDA and mGluR5 agonist, N-type and L-type Ca2+ channel activator, α4β2 nAChR potentiator. N-(2,6-dimethylphenyl)-2-(2-oxopyrrolidin-1-yl)acetamide DM-9384 77191-36-7 ≥98% 246.3 C14H18N2O2 CC1=C(C(=CC=C1)C)NC(=O)CN2CCCC2=O Ambient Ambient "Lu XC, Dave JR, Chen Z, et al. Nefiracetam attenuates post-ischemic nonconvulsive seizures in rats and protects neuronal cell death induced by veratridine and glutamate. Life Sci. 2013 Jun 13;92(22):1055-63. PMID: 23603142.

Malykh AG, Sadaie MR. Piracetam and piracetam-like drugs: from basic science to novel clinical applications to CNS disorders. Drugs. 2010 Feb 12;70(3):287-312. PMID: 20166767.

Moriguchi S, Han F, Shioda N, et al. Nefiracetam activation of CaM kinase II and protein kinase C mediated by NMDA and metabotropic glutamate receptors in olfactory bulbectomized mice. J Neurochem. 2009 Jul;110(1):170-81. PMID: 19457128.

Kitano Y, Komiyama C, Makino M, et al. Anticonvulsant and neuroprotective effects of the novel nootropic agent nefiracetam on kainic acid-induced seizures in rats. Brain Res. 2005 Sep 28;1057(1-2):168-76. PMID: 16122714.

Narahashi T, Moriguchi S, Zhao X, et al. Mechanisms of action of cognitive enhancers on neuroreceptors. Biol Pharm Bull. 2004 Nov;27(11):1701-6. PMID: 15516710.

Yoshii M, Watabe S, Murashima YL, et al. Cellular mechanism of action of cognitive enhancers: effects of nefiracetam on neuronal Ca2+ channels. Alzheimer Dis Assoc Disord. 2000;14 Suppl 1:S95-102. PMID: 10850736.

" Xn Not dangerous goods.

LKT N1721 Nefiracetam 250 mg 168.7 Pyrrolidone; NMDA and mGluR5 agonist, N-type and L-type Ca2+ channel activator, α4β2 nAChR potentiator. N-(2,6-dimethylphenyl)-2-(2-oxopyrrolidin-1-yl)acetamide DM-9384 77191-36-7 ≥98% 246.3 C14H18N2O2 CC1=C(C(=CC=C1)C)NC(=O)CN2CCCC2=O Ambient Ambient "Lu XC, Dave JR, Chen Z, et al. Nefiracetam attenuates post-ischemic nonconvulsive seizures in rats and protects neuronal cell death induced by veratridine and glutamate. Life Sci. 2013 Jun 13;92(22):1055-63. PMID: 23603142.

Malykh AG, Sadaie MR. Piracetam and piracetam-like drugs: from basic science to novel clinical applications to CNS disorders. Drugs. 2010 Feb 12;70(3):287-312. PMID: 20166767.

Moriguchi S, Han F, Shioda N, et al. Nefiracetam activation of CaM kinase II and protein kinase C mediated by NMDA and metabotropic glutamate receptors in olfactory bulbectomized mice. J Neurochem. 2009 Jul;110(1):170-81. PMID: 19457128.

Kitano Y, Komiyama C, Makino M, et al. Anticonvulsant and neuroprotective effects of the novel nootropic agent nefiracetam on kainic acid-induced seizures in rats. Brain Res. 2005 Sep 28;1057(1-2):168-76. PMID: 16122714.

Narahashi T, Moriguchi S, Zhao X, et al. Mechanisms of action of cognitive enhancers on neuroreceptors. Biol Pharm Bull. 2004 Nov;27(11):1701-6. PMID: 15516710.

Yoshii M, Watabe S, Murashima YL, et al. Cellular mechanism of action of cognitive enhancers: effects of nefiracetam on neuronal Ca2+ channels. Alzheimer Dis Assoc Disord. 2000;14 Suppl 1:S95-102. PMID: 10850736.

" Xn Not dangerous goods.

LKT N1721 Nefiracetam 1 g 515.7 Pyrrolidone; NMDA and mGluR5 agonist, N-type and L-type Ca2+ channel activator, α4β2 nAChR potentiator. N-(2,6-dimethylphenyl)-2-(2-oxopyrrolidin-1-yl)acetamide DM-9384 77191-36-7 ≥98% 246.3 C14H18N2O2 CC1=C(C(=CC=C1)C)NC(=O)CN2CCCC2=O Ambient Ambient "Lu XC, Dave JR, Chen Z, et al. Nefiracetam attenuates post-ischemic nonconvulsive seizures in rats and protects neuronal cell death induced by veratridine and glutamate. Life Sci. 2013 Jun 13;92(22):1055-63. PMID: 23603142.

Malykh AG, Sadaie MR. Piracetam and piracetam-like drugs: from basic science to novel clinical applications to CNS disorders. Drugs. 2010 Feb 12;70(3):287-312. PMID: 20166767.

Moriguchi S, Han F, Shioda N, et al. Nefiracetam activation of CaM kinase II and protein kinase C mediated by NMDA and metabotropic glutamate receptors in olfactory bulbectomized mice. J Neurochem. 2009 Jul;110(1):170-81. PMID: 19457128.

Kitano Y, Komiyama C, Makino M, et al. Anticonvulsant and neuroprotective effects of the novel nootropic agent nefiracetam on kainic acid-induced seizures in rats. Brain Res. 2005 Sep 28;1057(1-2):168-76. PMID: 16122714.

Narahashi T, Moriguchi S, Zhao X, et al. Mechanisms of action of cognitive enhancers on neuroreceptors. Biol Pharm Bull. 2004 Nov;27(11):1701-6. PMID: 15516710.

Yoshii M, Watabe S, Murashima YL, et al. Cellular mechanism of action of cognitive enhancers: effects of nefiracetam on neuronal Ca2+ channels. Alzheimer Dis Assoc Disord. 2000;14 Suppl 1:S95-102. PMID: 10850736.

" Xn Not dangerous goods.

LKT R3310 Ricobendazole 10 g 47.6 Nitroimidazole; microtubule polymerization inhibitor. (5-propylsulfinyl)-1H-benzimidazol-2-yl)-methyl ester carbamic acid (+-)-Albendazole sulfoxide; Albendazole oxide 54029-12-8 ≥98% 281.33 C12H15N3O3S CCCS(=O)C1=CC2=C(C=C1)N=C(N2)NC(=O)OC Ambient Ambient "Lopes WD, Cruz BC, Soares VE, et al. Historic of therapeutic efficacy of albendazol sulphoxide administered in different routes, dosages and treatment schemes, against Taenia saginata cysticercus in cattle experimentally infected. Exp Parasitol. 2014 Feb;137:14-20. PMID: 24309372.

Belaz KR, Denadai M, Almeida AP, et al. Enantiomeric resolution of albendazole sulfoxide by semipreparative HPLC and in vitro study of growth inhibitory effects on human cancer cell lines. J Pharm Biomed Anal. 2012 Jul;66:100-8. PMID: 22487592.

" Xn Not dangerous goods.

LKT R3310 Ricobendazole 25 g 81.6 Nitroimidazole; microtubule polymerization inhibitor. (5-propylsulfinyl)-1H-benzimidazol-2-yl)-methyl ester carbamic acid (+-)-Albendazole sulfoxide; Albendazole oxide 54029-12-8 ≥98% 281.33 C12H15N3O3S CCCS(=O)C1=CC2=C(C=C1)N=C(N2)NC(=O)OC Ambient Ambient "Lopes WD, Cruz BC, Soares VE, et al. Historic of therapeutic efficacy of albendazol sulphoxide administered in different routes, dosages and treatment schemes, against Taenia saginata cysticercus in cattle experimentally infected. Exp Parasitol. 2014 Feb;137:14-20. PMID: 24309372.

Belaz KR, Denadai M, Almeida AP, et al. Enantiomeric resolution of albendazole sulfoxide by semipreparative HPLC and in vitro study of growth inhibitory effects on human cancer cell lines. J Pharm Biomed Anal. 2012 Jul;66:100-8. PMID: 22487592.

" Xn Not dangerous goods.

LKT R3310 Ricobendazole 100 g 242.7 Nitroimidazole; microtubule polymerization inhibitor. (5-propylsulfinyl)-1H-benzimidazol-2-yl)-methyl ester carbamic acid (+-)-Albendazole sulfoxide; Albendazole oxide 54029-12-8 ≥98% 281.33 C12H15N3O3S CCCS(=O)C1=CC2=C(C=C1)N=C(N2)NC(=O)OC Ambient Ambient "Lopes WD, Cruz BC, Soares VE, et al. Historic of therapeutic efficacy of albendazol sulphoxide administered in different routes, dosages and treatment schemes, against Taenia saginata cysticercus in cattle experimentally infected. Exp Parasitol. 2014 Feb;137:14-20. PMID: 24309372.

Belaz KR, Denadai M, Almeida AP, et al. Enantiomeric resolution of albendazole sulfoxide by semipreparative HPLC and in vitro study of growth inhibitory effects on human cancer cell lines. J Pharm Biomed Anal. 2012 Jul;66:100-8. PMID: 22487592.

" Xn Not dangerous goods.

LKT R3249 Rimantadine Hydrochloride 25 mg 33.9 Viral M2 proton channel blocker. α-Methyltricyclo[3.3.1.13,7]decane-1-methanamine Flumadine; Meradan; Roflual 1501-84-4 ≥98% 215.76 C12H21N HCl CC(C12CC3CC(C1)CC(C3)C2)N.Cl Ambient Ambient Soluble in water. "Ivanovic T, Rozendaal R, Floyd DL, et al. Kinetics of proton transport into influenza virions by the viral M2 channel. PLoS One. 2012;7(3):e31566. PMID: 22412838.

Leonov H, Astrahan P, Krugliak M, et al. How do aminoadamantanes block the influenza M2 channel, and how does resistance develop? J Am Chem Soc. 2011 Jun 29;133(25):9903-11. PMID: 21534619.

" Xn Not dangerous goods.

LKT R3249 Rimantadine Hydrochloride 50 mg 47.6 Viral M2 proton channel blocker. α-Methyltricyclo[3.3.1.13,7]decane-1-methanamine Flumadine; Meradan; Roflual 1501-84-4 ≥98% 215.76 C12H21N HCl CC(C12CC3CC(C1)CC(C3)C2)N.Cl Ambient Ambient Soluble in water. "Ivanovic T, Rozendaal R, Floyd DL, et al. Kinetics of proton transport into influenza virions by the viral M2 channel. PLoS One. 2012;7(3):e31566. PMID: 22412838.

Leonov H, Astrahan P, Krugliak M, et al. How do aminoadamantanes block the influenza M2 channel, and how does resistance develop? J Am Chem Soc. 2011 Jun 29;133(25):9903-11. PMID: 21534619.

" Xn Not dangerous goods.

LKT R3224 Rigin 5 mg 72.1 Peptide, IgG derivative, tuftsin analog. G-Q-P-R; GQPR 77727-17-4 ≥95% 456.51 C18H32N8O6 C1CC(N(C1)C(=O)C(CCC(=O)N)NC(=O)CN)C(=O)NC(CCCN=C(N)N)C(=O)O Ambient -20°C "Dutta RC, Puri A, Anand N. Immunomodulatory potential of hydrophobic analogs of Rigin and their role in providing protection against Plasmodium berghei infection in mice. Int Immunopharmacol. 2001 May;1(5):843-55. PMID: 11379040.

Klusha VE, Mutsenietse RK, Svirskis ShV, et al. Neuroimmunoregulatory properties of short protein fragments in rats exposed to immobilization stress. Biull Eksp Biol Med. 1987 Aug;104(8):186-7. PMID: 2887222.

Veretennikova NI, Chipens GI, Nikiforovich GV, et al. Rigin, another phagocytosis-stimulating tetrapeptide isolated from human IgG. Confirmations of a hypothesis. Int J Pept Protein Res. 1981 Apr;17(4):430-5. PMID: 7309346.

"

LKT R3224 Rigin 10 mg 122.4 Peptide, IgG derivative, tuftsin analog. G-Q-P-R; GQPR 77727-17-4 ≥95% 456.51 C18H32N8O6 C1CC(N(C1)C(=O)C(CCC(=O)N)NC(=O)CN)C(=O)NC(CCCN=C(N)N)C(=O)O Ambient -20°C "Dutta RC, Puri A, Anand N. Immunomodulatory potential of hydrophobic analogs of Rigin and their role in providing protection against Plasmodium berghei infection in mice. Int Immunopharmacol. 2001 May;1(5):843-55. PMID: 11379040.

Klusha VE, Mutsenietse RK, Svirskis ShV, et al. Neuroimmunoregulatory properties of short protein fragments in rats exposed to immobilization stress. Biull Eksp Biol Med. 1987 Aug;104(8):186-7. PMID: 2887222.

Veretennikova NI, Chipens GI, Nikiforovich GV, et al. Rigin, another phagocytosis-stimulating tetrapeptide isolated from human IgG. Confirmations of a hypothesis. Int J Pept Protein Res. 1981 Apr;17(4):430-5. PMID: 7309346.

"

LKT R3224 Rigin 25 mg 216.1 Peptide, IgG derivative, tuftsin analog. G-Q-P-R; GQPR 77727-17-4 ≥95% 456.51 C18H32N8O6 C1CC(N(C1)C(=O)C(CCC(=O)N)NC(=O)CN)C(=O)NC(CCCN=C(N)N)C(=O)O Ambient -20°C "Dutta RC, Puri A, Anand N. Immunomodulatory potential of hydrophobic analogs of Rigin and their role in providing protection against Plasmodium berghei infection in mice. Int Immunopharmacol. 2001 May;1(5):843-55. PMID: 11379040.

Klusha VE, Mutsenietse RK, Svirskis ShV, et al. Neuroimmunoregulatory properties of short protein fragments in rats exposed to immobilization stress. Biull Eksp Biol Med. 1987 Aug;104(8):186-7. PMID: 2887222.

Veretennikova NI, Chipens GI, Nikiforovich GV, et al. Rigin, another phagocytosis-stimulating tetrapeptide isolated from human IgG. Confirmations of a hypothesis. Int J Pept Protein Res. 1981 Apr;17(4):430-5. PMID: 7309346.

"

LKT R3222 Rifamycin SV Monosodium 1 g 55 Ansamycin; bacterial DNA-dependent RNA polymerase inhibitor, RNA synthesis inhibitor. Rifamycin SV sodium salt; Rifamastene; Rifocin 14897-39-3 ≥98% 719.75 C37H46NNaO12 CC1C=CC=C(C(=O)NC2=CC(=C3C(=C2O)C(=C(C4=C3C(=O)C(O4)(OC=CC(C(C(C(C(C(C1O)C)O)C)OC(=O)C)C)OC)C)C)O)[O-])C.[Na+] Ambient Ambient Soluble in water (pH7.2). "Rosette C, Buendia-Laysa F Jr, Patkar S, et al. Anti-inflammatory and immunomodulatory activities of rifamycin SV. Int J Antimicrob Agents. 2013 Aug;42(2):182-6. PMID: 23756321.

Farrell DJ, Putnam SD, Biedenbach DJ, et al. In vitro activity and single-step mutational analysis of rifamycin SV tested against enteropathogens associated with traveler's diarrhea and Clostridium difficile. Antimicrob Agents Chemother. 2011 Mar;55(3):992-6. PMID: 21149623.

Campbell EA, Korzheva N, Mustaev A, et al. Structural mechanism for rifampicin inhibition of bacterial rna polymerase. Cell. 2001 Mar 23;104(6):901-12. PMID: 11290327.

" Not dangerous goods.

LKT R3222 Rifamycin SV Monosodium 5 g 178.3 Ansamycin; bacterial DNA-dependent RNA polymerase inhibitor, RNA synthesis inhibitor. Rifamycin SV sodium salt; Rifamastene; Rifocin 14897-39-3 ≥98% 719.75 C37H46NNaO12 CC1C=CC=C(C(=O)NC2=CC(=C3C(=C2O)C(=C(C4=C3C(=O)C(O4)(OC=CC(C(C(C(C(C(C1O)C)O)C)OC(=O)C)C)OC)C)C)O)[O-])C.[Na+] Ambient Ambient Soluble in water (pH7.2). "Rosette C, Buendia-Laysa F Jr, Patkar S, et al. Anti-inflammatory and immunomodulatory activities of rifamycin SV. Int J Antimicrob Agents. 2013 Aug;42(2):182-6. PMID: 23756321.

Farrell DJ, Putnam SD, Biedenbach DJ, et al. In vitro activity and single-step mutational analysis of rifamycin SV tested against enteropathogens associated with traveler's diarrhea and Clostridium difficile. Antimicrob Agents Chemother. 2011 Mar;55(3):992-6. PMID: 21149623.

Campbell EA, Korzheva N, Mustaev A, et al. Structural mechanism for rifampicin inhibition of bacterial rna polymerase. Cell. 2001 Mar 23;104(6):901-12. PMID: 11290327.

" Not dangerous goods.

LKT N1769 Nerolidol, synthetic 5 g 25.9 AChE inhibitor, F0F1-ATP synthase modulator. 3,7,11-Trimethyldodeca-1,6,10-trien-3-ol, 3-Hydroxy-3,7,11-trimethyl-1,6,10-dodectriene Stirrup; Peruviol 7212-44-4 A mixture of cis and trans isomers, ≥96% 222.37 C15H26O CC(=CCCC(=CCCC(C)(C=C)O)C)C Ambient Ambient Sparingly soluble in water. "Nogueira Neto JD, de Almeida AA, da Silva Oliveira J, et al. Antioxidant effects of nerolidol in mice hippocampus after open field test. Neurochem Res. 2013 Sep;38(9):1861-70. PMID: 23765368.

Tao R, Wang CZ, Kong ZW. Antibacterial/antifungal activity and synergistic interactions between polyprenols and other lipids isolated from Ginkgo biloba L. leaves. Molecules. 2013 Feb 7;18(2):2166-82. PMID: 23434869.

Kang JS, Kim E, Lee SH, et al. Inhibition of acetylcholinesterases of the pinewood nematode, Bursaphelenchus xylophilus, by phytochemicals from plant essential oils. Pestic Biochem Physiol. 2013 Jan;105(1):50-6. PMID: 24238290.

Ferreira FM, Palmeira CM, Oliveira MM, et al. Nerolidol effects on mitochondrial and cellular energetics. Toxicol In Vitro. 2012 Mar;26(2):189-96. PMID: 22138475.

" Xi Not dangerous goods.

LKT N1769 Nerolidol, synthetic 25 g 45.3 AChE inhibitor, F0F1-ATP synthase modulator. 3,7,11-Trimethyldodeca-1,6,10-trien-3-ol, 3-Hydroxy-3,7,11-trimethyl-1,6,10-dodectriene Stirrup; Peruviol 7212-44-4 A mixture of cis and trans isomers, ≥96% 222.37 C15H26O CC(=CCCC(=CCCC(C)(C=C)O)C)C Ambient Ambient Sparingly soluble in water. "Nogueira Neto JD, de Almeida AA, da Silva Oliveira J, et al. Antioxidant effects of nerolidol in mice hippocampus after open field test. Neurochem Res. 2013 Sep;38(9):1861-70. PMID: 23765368.

Tao R, Wang CZ, Kong ZW. Antibacterial/antifungal activity and synergistic interactions between polyprenols and other lipids isolated from Ginkgo biloba L. leaves. Molecules. 2013 Feb 7;18(2):2166-82. PMID: 23434869.

Kang JS, Kim E, Lee SH, et al. Inhibition of acetylcholinesterases of the pinewood nematode, Bursaphelenchus xylophilus, by phytochemicals from plant essential oils. Pestic Biochem Physiol. 2013 Jan;105(1):50-6. PMID: 24238290.

Ferreira FM, Palmeira CM, Oliveira MM, et al. Nerolidol effects on mitochondrial and cellular energetics. Toxicol In Vitro. 2012 Mar;26(2):189-96. PMID: 22138475.

" Xi Not dangerous goods.

LKT R3221 3-Formylrifamycin 1 g 82.4 Rifamycin derivative, induces pore formation in mitochondrial membranes; DNA-dependent RNA polymerase inhibitor. "2,7-(Epoxypentadeca(1,11,13)trienimino)naphtho(2,1-b)furan-

8-carboxaldehyde, 1,2-dihydro-5,6,9,17,19,21-hexahydroxy-23-

methoxy-2,4,12,16,18,20,22-heptamethyl-1,11-dioxo-, 21-

acetate" Rifamycin SV-3 formyl; 3-Formylrifampicin SV; Rifaldehyde; Rifamycin AF 13292-22-3 ≥98% 725.78 C38H47NO13 CC1C=CC=C(C(=O)NC2=C(C3=C(C4=C(C(=C3O)C)OC(C4=O)(OC=CC(C(C(C(C(C(C1O)C)O)C)OC(=O)C)C)OC)C)C(=C2C=O)O)O)C Ambient Ambient "Nedyalkova Z, Haladjova S, et al. QSAR Modeling of Antimycobacterial Activity and Activity Against Other Bacteria of 3-Formyl Rifamycin SV Derivatives. Mol inform. 2001 Nov;20(4): 298–318.

Sethi VS, Okano P. Interaction of rifamycins with mammalian nucleic acid polymerizing enzymes. Biochim Biophys Acta. 1976 Dec 1;454(2):230-47. PMID: 63293.

" Not dangerous goods.

LKT R3221 3-Formylrifamycin 5 g 307.7 Rifamycin derivative, induces pore formation in mitochondrial membranes; DNA-dependent RNA polymerase inhibitor. "2,7-(Epoxypentadeca(1,11,13)trienimino)naphtho(2,1-b)furan-

8-carboxaldehyde, 1,2-dihydro-5,6,9,17,19,21-hexahydroxy-23-

methoxy-2,4,12,16,18,20,22-heptamethyl-1,11-dioxo-, 21-

acetate" Rifamycin SV-3 formyl; 3-Formylrifampicin SV; Rifaldehyde; Rifamycin AF 13292-22-3 ≥98% 725.78 C38H47NO13 CC1C=CC=C(C(=O)NC2=C(C3=C(C4=C(C(=C3O)C)OC(C4=O)(OC=CC(C(C(C(C(C(C1O)C)O)C)OC(=O)C)C)OC)C)C(=C2C=O)O)O)C Ambient Ambient "Nedyalkova Z, Haladjova S, et al. QSAR Modeling of Antimycobacterial Activity and Activity Against Other Bacteria of 3-Formyl Rifamycin SV Derivatives. Mol inform. 2001 Nov;20(4): 298–318.

Sethi VS, Okano P. Interaction of rifamycins with mammalian nucleic acid polymerizing enzymes. Biochim Biophys Acta. 1976 Dec 1;454(2):230-47. PMID: 63293.

" Not dangerous goods.

LKT N1822 Nefazodone Hydrochloride 1 g 64.6 5-HT2 antagonist, SERT and NET inhibitor, hERG K+ channel blocker. 2-[3-[4-(3-Chlorophenyl)-1-piperazinyl]propyl]-5- ethyl-2,4-dihydro-4-(2-phenoxyethyl)-3H-1,2,4-triazol-3-one hydrochloride BMY-13754; MJ-13754-1; Dutonin; Serzone 82752-99-6 ≥98% 506.48 C25H32ClN5O2 HCl CCC1=NN(C(=O)N1CCOC2=CC=CC=C2)CCCN3CCN(CC3)C4=CC(=CC=C4)Cl.Cl Ambient Ambient Slightly soluble in water. "Shin DS, Park MJ, Lee HA, et al. A novel assessment of nefazodone-induced hERG inhibition by electrophysiological and stereochemical method. Toxicol Appl Pharmacol. 2014 Feb 1;274(3):361-71. PMID: 24374264.

Clayton AH, Montejo AL. Major depressive disorder, antidepressants, and sexual dysfunction. J Clin Psychiatry. 2006;67 Suppl 6:33-7. PMID: 16848675.

Dremencov E, Gispan-Herman I, Rosenstein M, et al. The serotonin-dopamine interaction is critical for fast-onset action of antidepressant treatment: in vivo studies in an animal model of depression. Prog Neuropsychopharmacol Biol Psychiatry. 2004 Jan;28(1):141-7. PMID: 14687868.

Eckler JR, Rabin RA, Winter JC. Nefazodone in the rat: mimicry and antagonism of [-]-DOM-induced stimulus control. Pharmacol Biochem Behav. 2003 May;75(2):405-10. PMID: 12873632.

" None Not dangerous goods.

LKT R3221 3-Formylrifamycin 10 g 556.2 Rifamycin derivative, induces pore formation in mitochondrial membranes; DNA-dependent RNA polymerase inhibitor. "2,7-(Epoxypentadeca(1,11,13)trienimino)naphtho(2,1-b)furan-

8-carboxaldehyde, 1,2-dihydro-5,6,9,17,19,21-hexahydroxy-23-

methoxy-2,4,12,16,18,20,22-heptamethyl-1,11-dioxo-, 21-

acetate" Rifamycin SV-3 formyl; 3-Formylrifampicin SV; Rifaldehyde; Rifamycin AF 13292-22-3 ≥98% 725.78 C38H47NO13 CC1C=CC=C(C(=O)NC2=C(C3=C(C4=C(C(=C3O)C)OC(C4=O)(OC=CC(C(C(C(C(C(C1O)C)O)C)OC(=O)C)C)OC)C)C(=C2C=O)O)O)C Ambient Ambient "Nedyalkova Z, Haladjova S, et al. QSAR Modeling of Antimycobacterial Activity and Activity Against Other Bacteria of 3-Formyl Rifamycin SV Derivatives. Mol inform. 2001 Nov;20(4): 298–318.

Sethi VS, Okano P. Interaction of rifamycins with mammalian nucleic acid polymerizing enzymes. Biochim Biophys Acta. 1976 Dec 1;454(2):230-47. PMID: 63293.

" Not dangerous goods.

LKT N1822 Nefazodone Hydrochloride 5 g 277.4 5-HT2 antagonist, SERT and NET inhibitor, hERG K+ channel blocker. 2-[3-[4-(3-Chlorophenyl)-1-piperazinyl]propyl]-5- ethyl-2,4-dihydro-4-(2-phenoxyethyl)-3H-1,2,4-triazol-3-one hydrochloride BMY-13754; MJ-13754-1; Dutonin; Serzone 82752-99-6 ≥98% 506.48 C25H32ClN5O2 HCl CCC1=NN(C(=O)N1CCOC2=CC=CC=C2)CCCN3CCN(CC3)C4=CC(=CC=C4)Cl.Cl Ambient Ambient Slightly soluble in water. "Shin DS, Park MJ, Lee HA, et al. A novel assessment of nefazodone-induced hERG inhibition by electrophysiological and stereochemical method. Toxicol Appl Pharmacol. 2014 Feb 1;274(3):361-71. PMID: 24374264.

Clayton AH, Montejo AL. Major depressive disorder, antidepressants, and sexual dysfunction. J Clin Psychiatry. 2006;67 Suppl 6:33-7. PMID: 16848675.

Dremencov E, Gispan-Herman I, Rosenstein M, et al. The serotonin-dopamine interaction is critical for fast-onset action of antidepressant treatment: in vivo studies in an animal model of depression. Prog Neuropsychopharmacol Biol Psychiatry. 2004 Jan;28(1):141-7. PMID: 14687868.

Eckler JR, Rabin RA, Winter JC. Nefazodone in the rat: mimicry and antagonism of [-]-DOM-induced stimulus control. Pharmacol Biochem Behav. 2003 May;75(2):405-10. PMID: 12873632.

" None Not dangerous goods.

LKT N1822 Nefazodone Hydrochloride 25 g 883.3 5-HT2 antagonist, SERT and NET inhibitor, hERG K+ channel blocker. 2-[3-[4-(3-Chlorophenyl)-1-piperazinyl]propyl]-5- ethyl-2,4-dihydro-4-(2-phenoxyethyl)-3H-1,2,4-triazol-3-one hydrochloride BMY-13754; MJ-13754-1; Dutonin; Serzone 82752-99-6 ≥98% 506.48 C25H32ClN5O2 HCl CCC1=NN(C(=O)N1CCOC2=CC=CC=C2)CCCN3CCN(CC3)C4=CC(=CC=C4)Cl.Cl Ambient Ambient Slightly soluble in water. "Shin DS, Park MJ, Lee HA, et al. A novel assessment of nefazodone-induced hERG inhibition by electrophysiological and stereochemical method. Toxicol Appl Pharmacol. 2014 Feb 1;274(3):361-71. PMID: 24374264.

Clayton AH, Montejo AL. Major depressive disorder, antidepressants, and sexual dysfunction. J Clin Psychiatry. 2006;67 Suppl 6:33-7. PMID: 16848675.

Dremencov E, Gispan-Herman I, Rosenstein M, et al. The serotonin-dopamine interaction is critical for fast-onset action of antidepressant treatment: in vivo studies in an animal model of depression. Prog Neuropsychopharmacol Biol Psychiatry. 2004 Jan;28(1):141-7. PMID: 14687868.

Eckler JR, Rabin RA, Winter JC. Nefazodone in the rat: mimicry and antagonism of [-]-DOM-induced stimulus control. Pharmacol Biochem Behav. 2003 May;75(2):405-10. PMID: 12873632.

" None Not dangerous goods.

LKT N1976 Netilmicin Sulfate 5 mg 231.1 Aminoglycoside; protein translation inhibitor. "O-3-deoxy-4-C-methyl-3-(methylamino)-β-L-arabino- pyranosyl-(1->6)-O-[2,6-diamino-2,3,4,6-tetradeoxy-

α-D-glycero-hex-4-enopyranosyl-(1->4)]-2-deoxy-N1-

ethyl-D-streptamine sulfate " Certomycin; Netilyn; Netromycin; Nettacin; Zetamicin 56391-57-2 ≥98% 1441.56 (C21H41N5O7)2 5HxSO4 CCNC1CC(C(C(C1OC2C(C(C(CO2)(C)O)NC)O)O)OC3C(CC=C(O3)CN)N)N.CCNC1CC(C(C(C1OC2C(C(C(CO2)(C)O)NC)O)O)OC3C(CC=C(O3)CN)N)N.OS(=O)(=O)O.OS(=O)(=O)O.OS(=O)(=O)O.OS(=O)(=O)O.OS(=O)(=O)O Ambient 4°C Soluble in water. "Wrześniok D, Beberok A, Otreba M, et al. Netilmicin-induced modulation of melanogenesis in HEMa-LP melanocytes. Acta Pol Pharm. 2013 Sep-Oct;70(5):803-8. PMID: 24147358.

Liu TX, Xue XD, Wei LH, et al. Study of plasmid-mediated 16S rRNA methylase genes and drug-resistant transferability of Acinetobacter baumannii isolated from burn ward. Zhonghua Shao Shang Za Zhi. 2009 Apr;25(2):98-102. PMID: 19799032.

" T Not dangerous goods.

LKT N1976 Netilmicin Sulfate 10 mg 346.5 Aminoglycoside; protein translation inhibitor. "O-3-deoxy-4-C-methyl-3-(methylamino)-β-L-arabino- pyranosyl-(1->6)-O-[2,6-diamino-2,3,4,6-tetradeoxy-

α-D-glycero-hex-4-enopyranosyl-(1->4)]-2-deoxy-N1-

ethyl-D-streptamine sulfate " Certomycin; Netilyn; Netromycin; Nettacin; Zetamicin 56391-57-2 ≥98% 1441.56 (C21H41N5O7)2 5HxSO4 CCNC1CC(C(C(C1OC2C(C(C(CO2)(C)O)NC)O)O)OC3C(CC=C(O3)CN)N)N.CCNC1CC(C(C(C1OC2C(C(C(CO2)(C)O)NC)O)O)OC3C(CC=C(O3)CN)N)N.OS(=O)(=O)O.OS(=O)(=O)O.OS(=O)(=O)O.OS(=O)(=O)O.OS(=O)(=O)O Ambient 4°C Soluble in water. "Wrześniok D, Beberok A, Otreba M, et al. Netilmicin-induced modulation of melanogenesis in HEMa-LP melanocytes. Acta Pol Pharm. 2013 Sep-Oct;70(5):803-8. PMID: 24147358.

Liu TX, Xue XD, Wei LH, et al. Study of plasmid-mediated 16S rRNA methylase genes and drug-resistant transferability of Acinetobacter baumannii isolated from burn ward. Zhonghua Shao Shang Za Zhi. 2009 Apr;25(2):98-102. PMID: 19799032.

" T Not dangerous goods.

LKT R3220 Rifampicin 1 g 49.5 Ansamycin; bacterial DNA-dependent RNA polymerase inhibitor, RNA synthesis inhibitor. 3-[[(4-Methyl-1-piperazinyl)imino]methyl]rifamycin Rifampin; Abrifam; Eremfat; Rifa; Rifaldin; Rifoldin 13292-46-1 ≥98% 822.94 C43H58N4O12 CC1C=CC=C(C(=O)NC2=C(C3=C(C(=C4C(=C3C(=O)C2=CNN5CCN(CC5)C)C(=O)C(O4)(OC=CC(C(C(C(C(C(C1O)C)O)C)OC(=O)C)C)OC)C)C)O)O)C Ambient Ambient Soluble in DMSO ethyl acetate, methanol and THF. Slightly soluble in water, acetone, and carbon terachloride, chloroform.  Water pH 4.3 to 1.3 mg/mL; Water pH 7.3 to 2.5 mg/mL. "Sharma SK, Sharma A, Kadhiravan T, et al. Rifamycins (rifampicin, rifabutin and rifapentine) compared to isoniazid for preventing tuberculosis in HIV-negative people at risk of active TB. Cochrane Database Syst Rev. 2013 Jul 5;7:CD007545. PMID: 23828580.

Bi W, Jing X, Zhu L, et al. Inhibition of 26S protease regulatory subunit 7 (MSS1) suppresses neuroinflammation. PLoS One. 2012;7(5):e36142. PMID: 22629310.

Qosa H, Abuznait AH, Hill RA, et al. Enhanced brain amyloid-β clearance by rifampicin and caffeine as a possible protective mechanism against Alzheimer's disease. J Alzheimers Dis. 2012;31(1):151-65. PMID: 22504320.

Campbell EA, Korzheva N, Mustaev A, et al. Structural mechanism for rifampicin inhibition of bacterial rna polymerase. Cell. 2001 Mar 23;104(6):901-12. PMID: 11290327.

" Xn, Xi Not dangerous goods.

LKT N1976 Netilmicin Sulfate 25 mg 693.2 Aminoglycoside; protein translation inhibitor. "O-3-deoxy-4-C-methyl-3-(methylamino)-β-L-arabino- pyranosyl-(1->6)-O-[2,6-diamino-2,3,4,6-tetradeoxy-

α-D-glycero-hex-4-enopyranosyl-(1->4)]-2-deoxy-N1-

ethyl-D-streptamine sulfate " Certomycin; Netilyn; Netromycin; Nettacin; Zetamicin 56391-57-2 ≥98% 1441.56 (C21H41N5O7)2 5HxSO4 CCNC1CC(C(C(C1OC2C(C(C(CO2)(C)O)NC)O)O)OC3C(CC=C(O3)CN)N)N.CCNC1CC(C(C(C1OC2C(C(C(CO2)(C)O)NC)O)O)OC3C(CC=C(O3)CN)N)N.OS(=O)(=O)O.OS(=O)(=O)O.OS(=O)(=O)O.OS(=O)(=O)O.OS(=O)(=O)O Ambient 4°C Soluble in water. "Wrześniok D, Beberok A, Otreba M, et al. Netilmicin-induced modulation of melanogenesis in HEMa-LP melanocytes. Acta Pol Pharm. 2013 Sep-Oct;70(5):803-8. PMID: 24147358.

Liu TX, Xue XD, Wei LH, et al. Study of plasmid-mediated 16S rRNA methylase genes and drug-resistant transferability of Acinetobacter baumannii isolated from burn ward. Zhonghua Shao Shang Za Zhi. 2009 Apr;25(2):98-102. PMID: 19799032.

" T Not dangerous goods.

LKT R3220 Rifampicin 5 g 164.7 Ansamycin; bacterial DNA-dependent RNA polymerase inhibitor, RNA synthesis inhibitor. 3-[[(4-Methyl-1-piperazinyl)imino]methyl]rifamycin Rifampin; Abrifam; Eremfat; Rifa; Rifaldin; Rifoldin 13292-46-1 ≥98% 822.94 C43H58N4O12 CC1C=CC=C(C(=O)NC2=C(C3=C(C(=C4C(=C3C(=O)C2=CNN5CCN(CC5)C)C(=O)C(O4)(OC=CC(C(C(C(C(C(C1O)C)O)C)OC(=O)C)C)OC)C)C)O)O)C Ambient Ambient Soluble in DMSO ethyl acetate, methanol and THF. Slightly soluble in water, acetone, and carbon terachloride, chloroform.  Water pH 4.3 to 1.3 mg/mL; Water pH 7.3 to 2.5 mg/mL. "Sharma SK, Sharma A, Kadhiravan T, et al. Rifamycins (rifampicin, rifabutin and rifapentine) compared to isoniazid for preventing tuberculosis in HIV-negative people at risk of active TB. Cochrane Database Syst Rev. 2013 Jul 5;7:CD007545. PMID: 23828580.

Bi W, Jing X, Zhu L, et al. Inhibition of 26S protease regulatory subunit 7 (MSS1) suppresses neuroinflammation. PLoS One. 2012;7(5):e36142. PMID: 22629310.

Qosa H, Abuznait AH, Hill RA, et al. Enhanced brain amyloid-β clearance by rifampicin and caffeine as a possible protective mechanism against Alzheimer's disease. J Alzheimers Dis. 2012;31(1):151-65. PMID: 22504320.

Campbell EA, Korzheva N, Mustaev A, et al. Structural mechanism for rifampicin inhibition of bacterial rna polymerase. Cell. 2001 Mar 23;104(6):901-12. PMID: 11290327.

" Xn, Xi Not dangerous goods.

LKT R3220 Rifampicin 25 g 617.5 Ansamycin; bacterial DNA-dependent RNA polymerase inhibitor, RNA synthesis inhibitor. 3-[[(4-Methyl-1-piperazinyl)imino]methyl]rifamycin Rifampin; Abrifam; Eremfat; Rifa; Rifaldin; Rifoldin 13292-46-1 ≥98% 822.94 C43H58N4O12 CC1C=CC=C(C(=O)NC2=C(C3=C(C(=C4C(=C3C(=O)C2=CNN5CCN(CC5)C)C(=O)C(O4)(OC=CC(C(C(C(C(C(C1O)C)O)C)OC(=O)C)C)OC)C)C)O)O)C Ambient Ambient Soluble in DMSO ethyl acetate, methanol and THF. Slightly soluble in water, acetone, and carbon terachloride, chloroform.  Water pH 4.3 to 1.3 mg/mL; Water pH 7.3 to 2.5 mg/mL. "Sharma SK, Sharma A, Kadhiravan T, et al. Rifamycins (rifampicin, rifabutin and rifapentine) compared to isoniazid for preventing tuberculosis in HIV-negative people at risk of active TB. Cochrane Database Syst Rev. 2013 Jul 5;7:CD007545. PMID: 23828580.

Bi W, Jing X, Zhu L, et al. Inhibition of 26S protease regulatory subunit 7 (MSS1) suppresses neuroinflammation. PLoS One. 2012;7(5):e36142. PMID: 22629310.

Qosa H, Abuznait AH, Hill RA, et al. Enhanced brain amyloid-β clearance by rifampicin and caffeine as a possible protective mechanism against Alzheimer's disease. J Alzheimers Dis. 2012;31(1):151-65. PMID: 22504320.

Campbell EA, Korzheva N, Mustaev A, et al. Structural mechanism for rifampicin inhibition of bacterial rna polymerase. Cell. 2001 Mar 23;104(6):901-12. PMID: 11290327.

" Xn, Xi Not dangerous goods.

LKT N1977 Neurokinin A (4-10) 1 mg 83.9 Endogenous neuropeptide, also known as substance K; NK1/2 agonist. Substance K 97559-35-8 ≥95% 766.92 C34H54N8O10S CC(C)CC(C(=O)NC(CCSC)C(=O)N)NC(=O)CNC(=O)C(C(C)C)NC(=O)C(CC1=CC=CC=C1)NC(=O)C(CO)NC(=O)C(CC(=O)O)N Ambient -20°C "Sun J, Ramnath RD, Tamizhselvi R, et al. Neurokinin A engages neurokinin-1 receptor to induce NF-kappaB-dependent gene expression in murine macrophages: implications of ERK1/2 and PI 3-kinase/Akt pathways. Am J Physiol Cell Physiol. 2008 Sep;295(3):C679-91. PMID: 18596216.

Fusco M, D'Andrea G, Miccichè F, et al. Neurogenic inflammation in primary headaches. Neurol Sci. 2003 May;24 Suppl 2:S61-4. PMID: 12811594.

Suzuki N, Mizuno K, Gomi Y. Tachykinin-induced contractions in the circular muscle of guinea pig ileum. Jpn J Pharmacol. 1994 Jul;65(3):233-40. PMID: 7528285.

" Not dangerous goods.

LKT N1977 Neurokinin A (4-10) 2 mg 142.8 Endogenous neuropeptide, also known as substance K; NK1/2 agonist. Substance K 97559-35-8 ≥95% 766.92 C34H54N8O10S CC(C)CC(C(=O)NC(CCSC)C(=O)N)NC(=O)CNC(=O)C(C(C)C)NC(=O)C(CC1=CC=CC=C1)NC(=O)C(CO)NC(=O)C(CC(=O)O)N Ambient -20°C "Sun J, Ramnath RD, Tamizhselvi R, et al. Neurokinin A engages neurokinin-1 receptor to induce NF-kappaB-dependent gene expression in murine macrophages: implications of ERK1/2 and PI 3-kinase/Akt pathways. Am J Physiol Cell Physiol. 2008 Sep;295(3):C679-91. PMID: 18596216.

Fusco M, D'Andrea G, Miccichè F, et al. Neurogenic inflammation in primary headaches. Neurol Sci. 2003 May;24 Suppl 2:S61-4. PMID: 12811594.

Suzuki N, Mizuno K, Gomi Y. Tachykinin-induced contractions in the circular muscle of guinea pig ileum. Jpn J Pharmacol. 1994 Jul;65(3):233-40. PMID: 7528285.

" Not dangerous goods.

LKT N1977 Neurokinin A (4-10) 5 mg 252.1 Endogenous neuropeptide, also known as substance K; NK1/2 agonist. Substance K 97559-35-8 ≥95% 766.92 C34H54N8O10S CC(C)CC(C(=O)NC(CCSC)C(=O)N)NC(=O)CNC(=O)C(C(C)C)NC(=O)C(CC1=CC=CC=C1)NC(=O)C(CO)NC(=O)C(CC(=O)O)N Ambient -20°C "Sun J, Ramnath RD, Tamizhselvi R, et al. Neurokinin A engages neurokinin-1 receptor to induce NF-kappaB-dependent gene expression in murine macrophages: implications of ERK1/2 and PI 3-kinase/Akt pathways. Am J Physiol Cell Physiol. 2008 Sep;295(3):C679-91. PMID: 18596216.

Fusco M, D'Andrea G, Miccichè F, et al. Neurogenic inflammation in primary headaches. Neurol Sci. 2003 May;24 Suppl 2:S61-4. PMID: 12811594.

Suzuki N, Mizuno K, Gomi Y. Tachykinin-induced contractions in the circular muscle of guinea pig ileum. Jpn J Pharmacol. 1994 Jul;65(3):233-40. PMID: 7528285.

" Not dangerous goods.

LKT R3206 Riboflavin 25 g 53.3 Essential vitamin (B2) found in vegetables, dairy, legumes, plays a role in metabolism and oxidation-reduction reactions. Vitamin B2; Lactoflavin; Vitamin G; Beflavin; Flavaxin 83-88-5 ≥97% 376.36 C17H20N4O6 CC1=CC2=C(C=C1C)N(C3=NC(=O)NC(=O)C3=N2)CC(C(C(CO)O)O)O Ambient Ambient Soluble in alcohol or dilute alkalies. Slightly soluble in benzyl alcohol or phenol. Insoluble in ether, chloroform, acetone or benzene.  "Taylor FR. Nutraceuticals and headache: the biological basis. Headache. 2011 Mar;51(3):484-501. PMID: 21352223.

Henriques BJ, Olsen RK, Bross P, et al. Emerging roles for riboflavin in functional rescue of mitochondrial β-oxidation flavoenzymes. Curr Med Chem. 2010;17(32):3842-54. PMID: 20858216.

" Xi Not dangerous goods.

LKT R3206 Riboflavin 100 g 133.5 Essential vitamin (B2) found in vegetables, dairy, legumes, plays a role in metabolism and oxidation-reduction reactions. Vitamin B2; Lactoflavin; Vitamin G; Beflavin; Flavaxin 83-88-5 ≥97% 376.36 C17H20N4O6 CC1=CC2=C(C=C1C)N(C3=NC(=O)NC(=O)C3=N2)CC(C(C(CO)O)O)O Ambient Ambient Soluble in alcohol or dilute alkalies. Slightly soluble in benzyl alcohol or phenol. Insoluble in ether, chloroform, acetone or benzene.  "Taylor FR. Nutraceuticals and headache: the biological basis. Headache. 2011 Mar;51(3):484-501. PMID: 21352223.

Henriques BJ, Olsen RK, Bross P, et al. Emerging roles for riboflavin in functional rescue of mitochondrial β-oxidation flavoenzymes. Curr Med Chem. 2010;17(32):3842-54. PMID: 20858216.

" Xi Not dangerous goods.

LKT N1978 Neurokinin B 1 mg 72.1 Neurokinin K 86933-75-7 ≥95% 1210.45 C55H79N13O14S2 CC(C)CC(C(=O)NC(CCSC)C(=O)N)NC(=O)CNC(=O)C(C(C)C)NC(=O)C(CC1=CC=CC=C1)NC(=O)C(CC2=CC=CC=C2)NC(=O)C(CC(=O)O)NC(=O)C(CC3=CN=CN3)NC(=O)C(CCSC)NC(=O)C(CC(=O)O)N Ambient -20°C "Ichiki T, Kuroishi KN, Gunjigake KK, et al. Neurokinin B activates the formation and bone resorption activity of rat osteoclasts. Neuropeptides. 2011 Jun;45(3):239-44. PMID: 21514667

Mantha AK, Moorthy K, Cowsik SM, et al. Neuroprotective role of neurokinin B (NKB) on beta-amyloid (25-35) induced toxicity in aging rat brain synaptosomes: involvement in oxidative stress and excitotoxicity. Biogerontology. 2006 Feb;7(1):1-17. PMID: 16518716.

Page NM, Woods RJ, Gardiner SM, et al. Excessive placental secretion of neurokinin B during the third trimester causes pre-eclampsia. Nature. 2000 Jun 15;405(6788):797-800. PMID: 10866201.

Suzuki N, Mizuno K, Gomi Y. Tachykinin-induced contractions in the circular muscle of guinea pig ileum. Jpn J Pharmacol. 1994 Jul;65(3):233-40. PMID: 7528285.

" Not dangerous goods.

LKT N1978 Neurokinin B 2 mg 122.4 Neurokinin K 86933-75-7 ≥95% 1210.45 C55H79N13O14S2 CC(C)CC(C(=O)NC(CCSC)C(=O)N)NC(=O)CNC(=O)C(C(C)C)NC(=O)C(CC1=CC=CC=C1)NC(=O)C(CC2=CC=CC=C2)NC(=O)C(CC(=O)O)NC(=O)C(CC3=CN=CN3)NC(=O)C(CCSC)NC(=O)C(CC(=O)O)N Ambient -20°C "Ichiki T, Kuroishi KN, Gunjigake KK, et al. Neurokinin B activates the formation and bone resorption activity of rat osteoclasts. Neuropeptides. 2011 Jun;45(3):239-44. PMID: 21514667

Mantha AK, Moorthy K, Cowsik SM, et al. Neuroprotective role of neurokinin B (NKB) on beta-amyloid (25-35) induced toxicity in aging rat brain synaptosomes: involvement in oxidative stress and excitotoxicity. Biogerontology. 2006 Feb;7(1):1-17. PMID: 16518716.

Page NM, Woods RJ, Gardiner SM, et al. Excessive placental secretion of neurokinin B during the third trimester causes pre-eclampsia. Nature. 2000 Jun 15;405(6788):797-800. PMID: 10866201.

Suzuki N, Mizuno K, Gomi Y. Tachykinin-induced contractions in the circular muscle of guinea pig ileum. Jpn J Pharmacol. 1994 Jul;65(3):233-40. PMID: 7528285.

" Not dangerous goods.

LKT N1978 Neurokinin B 5 mg 216.1 Neurokinin K 86933-75-7 ≥95% 1210.45 C55H79N13O14S2 CC(C)CC(C(=O)NC(CCSC)C(=O)N)NC(=O)CNC(=O)C(C(C)C)NC(=O)C(CC1=CC=CC=C1)NC(=O)C(CC2=CC=CC=C2)NC(=O)C(CC(=O)O)NC(=O)C(CC3=CN=CN3)NC(=O)C(CCSC)NC(=O)C(CC(=O)O)N Ambient -20°C "Ichiki T, Kuroishi KN, Gunjigake KK, et al. Neurokinin B activates the formation and bone resorption activity of rat osteoclasts. Neuropeptides. 2011 Jun;45(3):239-44. PMID: 21514667

Mantha AK, Moorthy K, Cowsik SM, et al. Neuroprotective role of neurokinin B (NKB) on beta-amyloid (25-35) induced toxicity in aging rat brain synaptosomes: involvement in oxidative stress and excitotoxicity. Biogerontology. 2006 Feb;7(1):1-17. PMID: 16518716.

Page NM, Woods RJ, Gardiner SM, et al. Excessive placental secretion of neurokinin B during the third trimester causes pre-eclampsia. Nature. 2000 Jun 15;405(6788):797-800. PMID: 10866201.

Suzuki N, Mizuno K, Gomi Y. Tachykinin-induced contractions in the circular muscle of guinea pig ileum. Jpn J Pharmacol. 1994 Jul;65(3):233-40. PMID: 7528285.

" Not dangerous goods.

LKT R3205 Ribavirin 50 mg 61.1 Purine nucleoside analog; DNA chain terminator. 1-β-D-Ribofuranosyl-1H-1,2,4-triazole-3-carboxamide Copegus; Ribamidil; RTCA; Varazid; Virazole 36791-04-5 ≥98% 244.21 C8H12N4O5 C1=NC(=NN1C2C(C(C(O2)CO)O)O)C(=O)N Ambient 4°C Soluble in water. "Pinilla-Macua I, Fernández-Calotti P, Pérez-Del-Pulgar S, et al. Ribavirin Uptake into Human Hepatocyte HHL5 Cells Is Enhanced by Interferon-α via up-Regulation of the Human Concentrative Nucleoside Transporter (hCNT2). Mol Pharm. 2014 Sep 2;11(9):3223-30. PMID: 24957263.

Parekh PJ, Shiffman ML. The role of interferon in the new era of hepatitis C treatments. Expert Rev Gastroenterol Hepatol. 2014 Aug;8(6):649-56. PMID: 24758387.

Wohl BM, Smith AA, Kryger MB, et al. Narrow therapeutic window of ribavirin as an inhibitor of nitric oxide synthesis is broadened by macromolecular prodrugs. Biomacromolecules. 2013 Nov 11;14(11):3916-26. PMID: 24156371.

" T Not dangerous goods.

LKT N1979 Neuromedin 1 mg 48 Endogenous proneurotensin peptide, involved in energy homeostasis. Neuromedin N 102577-25-3 ≥95% 745.97 C38H63N7O8 CCC(C)C(C(=O)NC(CC(C)C)C(=O)O)NC(=O)C(CC1=CC=C(C=C1)O)NC(=O)C2CCCN2C(=O)C(C(C)CC)NC(=O)C(CCCCN)N Ambient -20°C "Basir YJ, Knoop FC, Dulka J, et al. Multiple antimicrobial peptides and peptides related to bradykinin and neuromedin N isolated from skin secretions of the pickerel frog, Rana palustris. Biochim Biophys Acta. 2000 Nov 30;1543(1):95-105. PMID: 11087945.

Banker NA, Hellmich MR, Kim HJ, et al. Src-mediated activation of the human neurotensin/neuromedin N promoter. Surgery. 1997 Aug;122(2):180-6. PMID: 9288121.

Fernández R, Alba F, Ferrer JM. Peptidase inhibitors potentiate the effects of neurotensin and neuromedin N on self-stimulation of the medial prefrontal cortex. Neuroreport. 1996 Feb 29;7(3):798-800. PMID: 8733748.

Barelli H, Woskowska Z, Cipris S, et al. Pharmacological role and degradation processes of neuromedin N in the gastrointestinal tract: an in vitro and in vivo study. J Pharmacol Exp Ther. 1995 Dec;275(3):1300-7. PMID: 8531096.

Malendowicz LK, Nussdorfer GG, Markowska A, et al. Investigations on the acute effects of neuropeptides on the pituitary-adrenocortical function in normal and cold-stressed rats. II. Neurotensin and neuromedin N. Exp Toxicol Pathol. 1995 Jan;47(1):41-5. PMID: 7719120.

" Not dangerous goods.

LKT N1979 Neuromedin 2 mg 81.8 Endogenous proneurotensin peptide, involved in energy homeostasis. Neuromedin N 102577-25-3 ≥95% 745.97 C38H63N7O8 CCC(C)C(C(=O)NC(CC(C)C)C(=O)O)NC(=O)C(CC1=CC=C(C=C1)O)NC(=O)C2CCCN2C(=O)C(C(C)CC)NC(=O)C(CCCCN)N Ambient -20°C "Basir YJ, Knoop FC, Dulka J, et al. Multiple antimicrobial peptides and peptides related to bradykinin and neuromedin N isolated from skin secretions of the pickerel frog, Rana palustris. Biochim Biophys Acta. 2000 Nov 30;1543(1):95-105. PMID: 11087945.

Banker NA, Hellmich MR, Kim HJ, et al. Src-mediated activation of the human neurotensin/neuromedin N promoter. Surgery. 1997 Aug;122(2):180-6. PMID: 9288121.

Fernández R, Alba F, Ferrer JM. Peptidase inhibitors potentiate the effects of neurotensin and neuromedin N on self-stimulation of the medial prefrontal cortex. Neuroreport. 1996 Feb 29;7(3):798-800. PMID: 8733748.

Barelli H, Woskowska Z, Cipris S, et al. Pharmacological role and degradation processes of neuromedin N in the gastrointestinal tract: an in vitro and in vivo study. J Pharmacol Exp Ther. 1995 Dec;275(3):1300-7. PMID: 8531096.

Malendowicz LK, Nussdorfer GG, Markowska A, et al. Investigations on the acute effects of neuropeptides on the pituitary-adrenocortical function in normal and cold-stressed rats. II. Neurotensin and neuromedin N. Exp Toxicol Pathol. 1995 Jan;47(1):41-5. PMID: 7719120.

" Not dangerous goods.

LKT R3205 Ribavirin 100 mg 101.9 Purine nucleoside analog; DNA chain terminator. 1-β-D-Ribofuranosyl-1H-1,2,4-triazole-3-carboxamide Copegus; Ribamidil; RTCA; Varazid; Virazole 36791-04-5 ≥98% 244.21 C8H12N4O5 C1=NC(=NN1C2C(C(C(O2)CO)O)O)C(=O)N Ambient 4°C Soluble in water. "Pinilla-Macua I, Fernández-Calotti P, Pérez-Del-Pulgar S, et al. Ribavirin Uptake into Human Hepatocyte HHL5 Cells Is Enhanced by Interferon-α via up-Regulation of the Human Concentrative Nucleoside Transporter (hCNT2). Mol Pharm. 2014 Sep 2;11(9):3223-30. PMID: 24957263.

Parekh PJ, Shiffman ML. The role of interferon in the new era of hepatitis C treatments. Expert Rev Gastroenterol Hepatol. 2014 Aug;8(6):649-56. PMID: 24758387.

Wohl BM, Smith AA, Kryger MB, et al. Narrow therapeutic window of ribavirin as an inhibitor of nitric oxide synthesis is broadened by macromolecular prodrugs. Biomacromolecules. 2013 Nov 11;14(11):3916-26. PMID: 24156371.

" T Not dangerous goods.

LKT N1979 Neuromedin 5 mg 144 Endogenous proneurotensin peptide, involved in energy homeostasis. Neuromedin N 102577-25-3 ≥95% 745.97 C38H63N7O8 CCC(C)C(C(=O)NC(CC(C)C)C(=O)O)NC(=O)C(CC1=CC=C(C=C1)O)NC(=O)C2CCCN2C(=O)C(C(C)CC)NC(=O)C(CCCCN)N Ambient -20°C "Basir YJ, Knoop FC, Dulka J, et al. Multiple antimicrobial peptides and peptides related to bradykinin and neuromedin N isolated from skin secretions of the pickerel frog, Rana palustris. Biochim Biophys Acta. 2000 Nov 30;1543(1):95-105. PMID: 11087945.

Banker NA, Hellmich MR, Kim HJ, et al. Src-mediated activation of the human neurotensin/neuromedin N promoter. Surgery. 1997 Aug;122(2):180-6. PMID: 9288121.

Fernández R, Alba F, Ferrer JM. Peptidase inhibitors potentiate the effects of neurotensin and neuromedin N on self-stimulation of the medial prefrontal cortex. Neuroreport. 1996 Feb 29;7(3):798-800. PMID: 8733748.

Barelli H, Woskowska Z, Cipris S, et al. Pharmacological role and degradation processes of neuromedin N in the gastrointestinal tract: an in vitro and in vivo study. J Pharmacol Exp Ther. 1995 Dec;275(3):1300-7. PMID: 8531096.

Malendowicz LK, Nussdorfer GG, Markowska A, et al. Investigations on the acute effects of neuropeptides on the pituitary-adrenocortical function in normal and cold-stressed rats. II. Neurotensin and neuromedin N. Exp Toxicol Pathol. 1995 Jan;47(1):41-5. PMID: 7719120.

" Not dangerous goods.

LKT R3205 Ribavirin 500 mg 339.8 Purine nucleoside analog; DNA chain terminator. 1-β-D-Ribofuranosyl-1H-1,2,4-triazole-3-carboxamide Copegus; Ribamidil; RTCA; Varazid; Virazole 36791-04-5 ≥98% 244.21 C8H12N4O5 C1=NC(=NN1C2C(C(C(O2)CO)O)O)C(=O)N Ambient 4°C Soluble in water. "Pinilla-Macua I, Fernández-Calotti P, Pérez-Del-Pulgar S, et al. Ribavirin Uptake into Human Hepatocyte HHL5 Cells Is Enhanced by Interferon-α via up-Regulation of the Human Concentrative Nucleoside Transporter (hCNT2). Mol Pharm. 2014 Sep 2;11(9):3223-30. PMID: 24957263.

Parekh PJ, Shiffman ML. The role of interferon in the new era of hepatitis C treatments. Expert Rev Gastroenterol Hepatol. 2014 Aug;8(6):649-56. PMID: 24758387.

Wohl BM, Smith AA, Kryger MB, et al. Narrow therapeutic window of ribavirin as an inhibitor of nitric oxide synthesis is broadened by macromolecular prodrugs. Biomacromolecules. 2013 Nov 11;14(11):3916-26. PMID: 24156371.

" T Not dangerous goods.

LKT N1980 Neuromedin B, pig 5 mg 287.9 Endogenous bombesin-related peptide, involved in endocrine signaling and feeding behavior; BB1 agonist. "1-glycine-2-L-asparagine-3-L-leucine-4-de-L-

glutamine-7-L-threonine-Ranatensin" 87096-84-2 ≥95% 1132.3 C52H73N15O12S CC(C)CC(C(=O)NC(CC1=CNC2=CC=CC=C21)C(=O)NC(C)C(=O)NC(C(C)O)C(=O)NCC(=O)NC(CC3=CN=CN3)C(=O)NC(CC4=CC=CC=C4)C(=O)NC(CCSC)C(=O)N)NC(=O)C(CC(=O)N)NC(=O)CN Ambient -20°C "Boughton CK, Patel SA, Thompson EL, et al. Neuromedin B stimulates the hypothalamic-pituitary-gonadal axis in male rats. Regul Pept. 2013 Nov 10;187:6-11. PMID: 24120470.

Saito H, Nakamachi T, Inoue K, et al. Autocrine effects of neuromedin B stimulate the proliferation of rat primary osteoblasts. J Endocrinol. 2013 Apr 15;217(2):141-50. PMID: 23428580.

Sayegh AI. The role of bombesin and bombesin-related peptides in the short-term control of food intake. Prog Mol Biol Transl Sci. 2013;114:343-70. PMID: 23317790.

" Not dangerous goods.

LKT N1980 Neuromedin B, pig 2 mg 163.4 Endogenous bombesin-related peptide, involved in endocrine signaling and feeding behavior; BB1 agonist. "1-glycine-2-L-asparagine-3-L-leucine-4-de-L-

glutamine-7-L-threonine-Ranatensin" 87096-84-2 ≥95% 1132.3 C52H73N15O12S CC(C)CC(C(=O)NC(CC1=CNC2=CC=CC=C21)C(=O)NC(C)C(=O)NC(C(C)O)C(=O)NCC(=O)NC(CC3=CN=CN3)C(=O)NC(CC4=CC=CC=C4)C(=O)NC(CCSC)C(=O)N)NC(=O)C(CC(=O)N)NC(=O)CN Ambient -20°C "Boughton CK, Patel SA, Thompson EL, et al. Neuromedin B stimulates the hypothalamic-pituitary-gonadal axis in male rats. Regul Pept. 2013 Nov 10;187:6-11. PMID: 24120470.

Saito H, Nakamachi T, Inoue K, et al. Autocrine effects of neuromedin B stimulate the proliferation of rat primary osteoblasts. J Endocrinol. 2013 Apr 15;217(2):141-50. PMID: 23428580.

Sayegh AI. The role of bombesin and bombesin-related peptides in the short-term control of food intake. Prog Mol Biol Transl Sci. 2013;114:343-70. PMID: 23317790.

" Not dangerous goods.

LKT N1980 Neuromedin B, pig 1 mg 96 Endogenous bombesin-related peptide, involved in endocrine signaling and feeding behavior; BB1 agonist. "1-glycine-2-L-asparagine-3-L-leucine-4-de-L-

glutamine-7-L-threonine-Ranatensin" 87096-84-2 ≥95% 1132.3 C52H73N15O12S CC(C)CC(C(=O)NC(CC1=CNC2=CC=CC=C21)C(=O)NC(C)C(=O)NC(C(C)O)C(=O)NCC(=O)NC(CC3=CN=CN3)C(=O)NC(CC4=CC=CC=C4)C(=O)NC(CCSC)C(=O)N)NC(=O)C(CC(=O)N)NC(=O)CN Ambient -20°C "Boughton CK, Patel SA, Thompson EL, et al. Neuromedin B stimulates the hypothalamic-pituitary-gonadal axis in male rats. Regul Pept. 2013 Nov 10;187:6-11. PMID: 24120470.

Saito H, Nakamachi T, Inoue K, et al. Autocrine effects of neuromedin B stimulate the proliferation of rat primary osteoblasts. J Endocrinol. 2013 Apr 15;217(2):141-50. PMID: 23428580.

Sayegh AI. The role of bombesin and bombesin-related peptides in the short-term control of food intake. Prog Mol Biol Transl Sci. 2013;114:343-70. PMID: 23317790.

" Not dangerous goods.

LKT "N1981

" Neuromedin C (18-27), pig 1 mg 149.9 Endogenous bombesin-related peptide, involved in endocrine signaling and feeding behavior; BB2 agonist. Bombesin decapeptide; Gastrin releasing peptide; GRP 81608-30-2 ≥98% 1120.3 C50H73N17O11S CC(C)CC(C(=O)NC(CCSC)C(=O)N)NC(=O)C(CC1=CN=CN1)NC(=O)CNC(=O)C(C(C)C)NC(=O)C(C)NC(=O)C(CC2=CNC3=CC=CC=C32)NC(=O)C(CC4=CN=CN4)NC(=O)C(CC(=O)N)NC(=O)CN Ambient -20°C Soluble in water. "Sayegh AI. The role of bombesin and bombesin-related peptides in the short-term control of food intake. Prog Mol Biol Transl Sci. 2013;114:343-70. PMID: 23317790.

Andoh T, Kuwazono T, Lee JB, et al. Gastrin-releasing peptide induces itch-related responses through mast cell degranulation in mice. Peptides. 2011 Oct;32(10):2098-103. PMID: 21933692.

Fekete EM, Bagi EE, Tóth K, et al. Neuromedin C microinjected into the amygdala inhibits feeding. Brain Res Bull. 2007 Jan 9;71(4):386-92. PMID: 17208656.

"

LKT N1982 Neuromedin U, rat 1 mg 204.1 Endogenous neuropeptide, involved in energy homeostasis; neuromedin agonist. 117505-80-3 ≥95% 2643.03 C124H180N34O31 Ambient -20°C "Helfer G, Ross AW, Morgan PJ. Neuromedin U partly mimics thyroid stimulating hormone and triggers Wnt/β-Catenin signalling in the photoperiodic response of F344 rats. J Neuroendocrinol. 2013 Oct 24. [Epub ahead of print]. PMID: 24164054.

Telegdy G, Adamik A. Anxiolytic action of neuromedin-U and neurotransmitters involved in mice. Regul Pept. 2013 Sep 10;186:137-40. PMID: 23892031.

Lin TY, Wu FJ, Lee WY, et al. Ovarian regulation of neuromedin U and its local actions in the ovary, mediated through neuromedin U receptor 2. Am J Physiol Endocrinol Metab. 2013 Apr 15;304(8):E800-9. PMID: 23423171.

Rahman AA, Shahid IZ, Pilowsky PM. Differential cardiorespiratory and sympathetic reflex responses to microinjection of neuromedin U in rat rostral ventrolateral medulla. J Pharmacol Exp Ther. 2012 Apr;341(1):213-24. PMID: 22262923.

Kono T, Hamasuna S, Korenaga H, et al. The role of neuromedin U during inflammatory response in the common carp. Fish Shellfish Immunol. 2012 Jan;32(1):151-60. PMID: 22122861.

" Not dangerous goods.

LKT N1982 Neuromedin U, rat 2 mg 346.9 Endogenous neuropeptide, involved in energy homeostasis; neuromedin agonist. 117505-80-3 ≥95% 2643.03 C124H180N34O31 Ambient -20°C "Helfer G, Ross AW, Morgan PJ. Neuromedin U partly mimics thyroid stimulating hormone and triggers Wnt/β-Catenin signalling in the photoperiodic response of F344 rats. J Neuroendocrinol. 2013 Oct 24. [Epub ahead of print]. PMID: 24164054.

Telegdy G, Adamik A. Anxiolytic action of neuromedin-U and neurotransmitters involved in mice. Regul Pept. 2013 Sep 10;186:137-40. PMID: 23892031.

Lin TY, Wu FJ, Lee WY, et al. Ovarian regulation of neuromedin U and its local actions in the ovary, mediated through neuromedin U receptor 2. Am J Physiol Endocrinol Metab. 2013 Apr 15;304(8):E800-9. PMID: 23423171.

Rahman AA, Shahid IZ, Pilowsky PM. Differential cardiorespiratory and sympathetic reflex responses to microinjection of neuromedin U in rat rostral ventrolateral medulla. J Pharmacol Exp Ther. 2012 Apr;341(1):213-24. PMID: 22262923.

Kono T, Hamasuna S, Korenaga H, et al. The role of neuromedin U during inflammatory response in the common carp. Fish Shellfish Immunol. 2012 Jan;32(1):151-60. PMID: 22122861.

" Not dangerous goods.

LKT N1982 Neuromedin U, rat 5 mg 612.4 Endogenous neuropeptide, involved in energy homeostasis; neuromedin agonist. 117505-80-3 ≥95% 2643.03 C124H180N34O31 Ambient -20°C "Helfer G, Ross AW, Morgan PJ. Neuromedin U partly mimics thyroid stimulating hormone and triggers Wnt/β-Catenin signalling in the photoperiodic response of F344 rats. J Neuroendocrinol. 2013 Oct 24. [Epub ahead of print]. PMID: 24164054.

Telegdy G, Adamik A. Anxiolytic action of neuromedin-U and neurotransmitters involved in mice. Regul Pept. 2013 Sep 10;186:137-40. PMID: 23892031.

Lin TY, Wu FJ, Lee WY, et al. Ovarian regulation of neuromedin U and its local actions in the ovary, mediated through neuromedin U receptor 2. Am J Physiol Endocrinol Metab. 2013 Apr 15;304(8):E800-9. PMID: 23423171.

Rahman AA, Shahid IZ, Pilowsky PM. Differential cardiorespiratory and sympathetic reflex responses to microinjection of neuromedin U in rat rostral ventrolateral medulla. J Pharmacol Exp Ther. 2012 Apr;341(1):213-24. PMID: 22262923.

Kono T, Hamasuna S, Korenaga H, et al. The role of neuromedin U during inflammatory response in the common carp. Fish Shellfish Immunol. 2012 Jan;32(1):151-60. PMID: 22122861.

" Not dangerous goods.

LKT R2917 Rhein 100 mg 95.1 Diacerein metabolite, anthraquinone found in Rheus. 9,10-Dihydro-4,5-dihydroxy-9,10-dioxo-2-anthracenecarboxylic acid Rhubarb yellow; Monorhein; Rheic acid; Cassic acid; Parietic acid 478-43-3 ≥88% 284.22 C15H8O6 C1=CC2=C(C(=C1)O)C(=O)C3=C(C=C(C=C3C2=O)C(=O)O)O Ambient 4°C Practically insoluble in water. Soluble in alkalies and pyridine. "Gao Y, Chen X, Fang L, et al. Rhein exerts pro- and anti-inflammatory actions by targeting IKKβ inhibition in LPS-activated macrophages. Free Radic Biol Med. 2014 Jul;72:104-12. PMID: 24721152.

Liu J, Chen Z, Zhang Y, et al. Rhein protects pancreatic β-cells from dynamin-related protein-1-mediated mitochondrial fission and cell apoptosis under hyperglycemia. Diabetes. 2013 Nov;62(11):3927-35. PMID: 23919963.

Li Y, Xu Y, Lei B, et al. Rhein induces apoptosis of human gastric cancer SGC-7901 cells via an intrinsic mitochondrial pathway. Braz J Med Biol Res. 2012 Nov;45(11):1052-9. PMID: 22850871.

Zhong XF, Huang GD, Luo T, et al. Protective effect of rhein against oxidative stress-related endothelial cell injury. Mol Med Rep. 2012 May;5(5):1261-6. PMID: 22344690.

He ZH, Zhou R, He MF, et al. Anti-angiogenic effect and mechanism of rhein from Rhizoma Rhei. Phytomedicine. 2011 Apr 15;18(6):470-8. PMID: 21112197.

" Xi Not dangerous goods.

LKT R2917 Rhein 500 mg 380.5 Diacerein metabolite, anthraquinone found in Rheus. 9,10-Dihydro-4,5-dihydroxy-9,10-dioxo-2-anthracenecarboxylic acid Rhubarb yellow; Monorhein; Rheic acid; Cassic acid; Parietic acid 478-43-3 ≥88% 284.22 C15H8O6 C1=CC2=C(C(=C1)O)C(=O)C3=C(C=C(C=C3C2=O)C(=O)O)O Ambient 4°C Practically insoluble in water. Soluble in alkalies and pyridine. "Gao Y, Chen X, Fang L, et al. Rhein exerts pro- and anti-inflammatory actions by targeting IKKβ inhibition in LPS-activated macrophages. Free Radic Biol Med. 2014 Jul;72:104-12. PMID: 24721152.

Liu J, Chen Z, Zhang Y, et al. Rhein protects pancreatic β-cells from dynamin-related protein-1-mediated mitochondrial fission and cell apoptosis under hyperglycemia. Diabetes. 2013 Nov;62(11):3927-35. PMID: 23919963.

Li Y, Xu Y, Lei B, et al. Rhein induces apoptosis of human gastric cancer SGC-7901 cells via an intrinsic mitochondrial pathway. Braz J Med Biol Res. 2012 Nov;45(11):1052-9. PMID: 22850871.

Zhong XF, Huang GD, Luo T, et al. Protective effect of rhein against oxidative stress-related endothelial cell injury. Mol Med Rep. 2012 May;5(5):1261-6. PMID: 22344690.

He ZH, Zhou R, He MF, et al. Anti-angiogenic effect and mechanism of rhein from Rhizoma Rhei. Phytomedicine. 2011 Apr 15;18(6):470-8. PMID: 21112197.

" Xi Not dangerous goods.

LKT R2917 Rhein 1 g 706.7 Diacerein metabolite, anthraquinone found in Rheus. 9,10-Dihydro-4,5-dihydroxy-9,10-dioxo-2-anthracenecarboxylic acid Rhubarb yellow; Monorhein; Rheic acid; Cassic acid; Parietic acid 478-43-3 ≥88% 284.22 C15H8O6 C1=CC2=C(C(=C1)O)C(=O)C3=C(C=C(C=C3C2=O)C(=O)O)O Ambient 4°C Practically insoluble in water. Soluble in alkalies and pyridine. "Gao Y, Chen X, Fang L, et al. Rhein exerts pro- and anti-inflammatory actions by targeting IKKβ inhibition in LPS-activated macrophages. Free Radic Biol Med. 2014 Jul;72:104-12. PMID: 24721152.

Liu J, Chen Z, Zhang Y, et al. Rhein protects pancreatic β-cells from dynamin-related protein-1-mediated mitochondrial fission and cell apoptosis under hyperglycemia. Diabetes. 2013 Nov;62(11):3927-35. PMID: 23919963.

Li Y, Xu Y, Lei B, et al. Rhein induces apoptosis of human gastric cancer SGC-7901 cells via an intrinsic mitochondrial pathway. Braz J Med Biol Res. 2012 Nov;45(11):1052-9. PMID: 22850871.

Zhong XF, Huang GD, Luo T, et al. Protective effect of rhein against oxidative stress-related endothelial cell injury. Mol Med Rep. 2012 May;5(5):1261-6. PMID: 22344690.

He ZH, Zhou R, He MF, et al. Anti-angiogenic effect and mechanism of rhein from Rhizoma Rhei. Phytomedicine. 2011 Apr 15;18(6):470-8. PMID: 21112197.

" Xi Not dangerous goods.

LKT R2599 RGYSLG 1 mg 72.1 Peptide, represents generic protein kinase active site. 110590-63-1 ≥95% 651.73 C28H45N9O9 CCC(C)C(C(=O)NCC(=O)NC(CO)C(=O)NC(CCCN=C(N)N)C(=O)O)NC(=O)C(CC1=CC=C(C=C1)O)NC(=O)CN Ambient -20°C Pattanaik A, Gowda DC, Urry DW. Phosphorylation and dephosphorylation modulation of an inverse temperature transition. Biochem Biophys Res Commun. 1991 Jul 31;178(2):539-45. PMID: 1859415.

LKT R2599 RGYSLG 2 mg 122.4 Peptide, represents generic protein kinase active site. 110590-63-1 ≥95% 651.73 C28H45N9O9 CCC(C)C(C(=O)NCC(=O)NC(CO)C(=O)NC(CCCN=C(N)N)C(=O)O)NC(=O)C(CC1=CC=C(C=C1)O)NC(=O)CN Ambient -20°C Pattanaik A, Gowda DC, Urry DW. Phosphorylation and dephosphorylation modulation of an inverse temperature transition. Biochem Biophys Res Commun. 1991 Jul 31;178(2):539-45. PMID: 1859415.

LKT R2599 RGYSLG 5 mg 216.1 Peptide, represents generic protein kinase active site. 110590-63-1 ≥95% 651.73 C28H45N9O9 CCC(C)C(C(=O)NCC(=O)NC(CO)C(=O)NC(CCCN=C(N)N)C(=O)O)NC(=O)C(CC1=CC=C(C=C1)O)NC(=O)CN Ambient -20°C Pattanaik A, Gowda DC, Urry DW. Phosphorylation and dephosphorylation modulation of an inverse temperature transition. Biochem Biophys Res Commun. 1991 Jul 31;178(2):539-45. PMID: 1859415.

LKT R2516 RGES 0.5 mg 48 Peptide, used as control to measure RGDS peptide activity. 93674-97-6 ≥95% 447.45 C16H29N7O8 "C(CC(C(=O)NCC(=O)NC(CCC(=O)O)C(=O)NC(CO)C(=O)O)N)CNC(=N)N

" Ambient -20°C "Philippeaux MM, Bargetzi JP, Pache JC, et al. Culture and functional studies of mouse macrophages on native-like fibrillar type I collagen. Eur J Cell Biol. 2009 Apr;88(4):243-56. PMID: 19124174.

Davids BJ, Yoshino TP. Integrin-like RGD-dependent binding mechanism involved in the spreading response of circulating molluscan phagocytes. Dev Comp Immunol. 1998 Jan-Feb;22(1):39-53. PMID: 9617582.

" Not dangerous goods.

LKT R2516 RGES 1 mg 81.8 Peptide, used as control to measure RGDS peptide activity. 93674-97-6 ≥95% 447.45 C16H29N7O8 "C(CC(C(=O)NCC(=O)NC(CCC(=O)O)C(=O)NC(CO)C(=O)O)N)CNC(=N)N

" Ambient -20°C "Philippeaux MM, Bargetzi JP, Pache JC, et al. Culture and functional studies of mouse macrophages on native-like fibrillar type I collagen. Eur J Cell Biol. 2009 Apr;88(4):243-56. PMID: 19124174.

Davids BJ, Yoshino TP. Integrin-like RGD-dependent binding mechanism involved in the spreading response of circulating molluscan phagocytes. Dev Comp Immunol. 1998 Jan-Feb;22(1):39-53. PMID: 9617582.

" Not dangerous goods.

LKT R2516 RGES 2.5 mg 144 Peptide, used as control to measure RGDS peptide activity. 93674-97-6 ≥95% 447.45 C16H29N7O8 "C(CC(C(=O)NCC(=O)NC(CCC(=O)O)C(=O)NC(CO)C(=O)O)N)CNC(=N)N

" Ambient -20°C "Philippeaux MM, Bargetzi JP, Pache JC, et al. Culture and functional studies of mouse macrophages on native-like fibrillar type I collagen. Eur J Cell Biol. 2009 Apr;88(4):243-56. PMID: 19124174.

Davids BJ, Yoshino TP. Integrin-like RGD-dependent binding mechanism involved in the spreading response of circulating molluscan phagocytes. Dev Comp Immunol. 1998 Jan-Feb;22(1):39-53. PMID: 9617582.

" Not dangerous goods.

LKT R2514 RGDV 5 mg 60 Tretraeptide, binds cell surface integrins. Arginyl-glycyl-aspartyl-valine Rgdv tetrapeptide 93674-99-8 ≥98% 445.5 C17H31N7O7 CC(C)C(C(=O)O)NC(=O)C(CC(=O)O)NC(=O)CNC(=O)C(CCCN=C(N)N)N Ambient -20°C "Jin S, Wang Y, Zhu H, et al. Nanosized aspirin-Arg-Gly-Asp-Val: delivery of aspirin to thrombus by the target carrier Arg-Gly-Asp-Val tetrapeptide. ACS Nano. 2013 Sep 24;7(9):7664-73. PMID: 23931063.

Wang F, Cui C, Ren Z, et al. Preparation and biological evaluation of tumor-specific Ara-C liposomal preparations containing RGDV motif. J Pharm Sci. 2012 Dec;101(12):4559-68. PMID: 23023730.

Zhao M, Wang C, Jiang X, et al. Synthesis of RGD containing peptides and their bioactivities. Prep Biochem Biotechnol. 2002 Nov;32(4):363-80. PMID: 12455829.

Preferred conformations of RGDX tetrapeptides to inhibit the binding of fibrinogen to platelets.

Park HS, Kim C, Kang YK. Biopolymers. 2002 Apr 15;63(5):298-313. PMID: 11877740.

" Not dangerous goods.

LKT R2514 RGDV 10 mg 101.9 Tretraeptide, binds cell surface integrins. Arginyl-glycyl-aspartyl-valine Rgdv tetrapeptide 93674-99-8 ≥98% 445.5 C17H31N7O7 CC(C)C(C(=O)O)NC(=O)C(CC(=O)O)NC(=O)CNC(=O)C(CCCN=C(N)N)N Ambient -20°C "Jin S, Wang Y, Zhu H, et al. Nanosized aspirin-Arg-Gly-Asp-Val: delivery of aspirin to thrombus by the target carrier Arg-Gly-Asp-Val tetrapeptide. ACS Nano. 2013 Sep 24;7(9):7664-73. PMID: 23931063.

Wang F, Cui C, Ren Z, et al. Preparation and biological evaluation of tumor-specific Ara-C liposomal preparations containing RGDV motif. J Pharm Sci. 2012 Dec;101(12):4559-68. PMID: 23023730.

Zhao M, Wang C, Jiang X, et al. Synthesis of RGD containing peptides and their bioactivities. Prep Biochem Biotechnol. 2002 Nov;32(4):363-80. PMID: 12455829.

Preferred conformations of RGDX tetrapeptides to inhibit the binding of fibrinogen to platelets.

Park HS, Kim C, Kang YK. Biopolymers. 2002 Apr 15;63(5):298-313. PMID: 11877740.

" Not dangerous goods.

LKT R2514 RGDV 25 mg 180 Tretraeptide, binds cell surface integrins. Arginyl-glycyl-aspartyl-valine Rgdv tetrapeptide 93674-99-8 ≥98% 445.5 C17H31N7O7 CC(C)C(C(=O)O)NC(=O)C(CC(=O)O)NC(=O)CNC(=O)C(CCCN=C(N)N)N Ambient -20°C "Jin S, Wang Y, Zhu H, et al. Nanosized aspirin-Arg-Gly-Asp-Val: delivery of aspirin to thrombus by the target carrier Arg-Gly-Asp-Val tetrapeptide. ACS Nano. 2013 Sep 24;7(9):7664-73. PMID: 23931063.

Wang F, Cui C, Ren Z, et al. Preparation and biological evaluation of tumor-specific Ara-C liposomal preparations containing RGDV motif. J Pharm Sci. 2012 Dec;101(12):4559-68. PMID: 23023730.

Zhao M, Wang C, Jiang X, et al. Synthesis of RGD containing peptides and their bioactivities. Prep Biochem Biotechnol. 2002 Nov;32(4):363-80. PMID: 12455829.

Preferred conformations of RGDX tetrapeptides to inhibit the binding of fibrinogen to platelets.

Park HS, Kim C, Kang YK. Biopolymers. 2002 Apr 15;63(5):298-313. PMID: 11877740.

" Not dangerous goods.

LKT R2513 RGDS 5 mg 90.1 Tetrapeptide, binds cell surface integrins. Arginyl-glycyl-aspartyl-serine Fibronectin tetrapeptide 91037-65-9 ≥95% 433.4 C15H27N7O8 C(CC(C(=O)NCC(=O)NC(CC(=O)O)C(=O)NC(CO)C(=O)O)N)CN=C(N)N Ambient -20°C "Inoue T, Hashimoto R, Matsumoto A, et al. In vivo Analysis of Arg-Gly-Asp Sequence/Integrin α5β1-Mediated Signal Involvement in Embryonic Enchondral Ossification by exo utero Development System. J Bone Miner Res. 2013 Dec 27. [Epub ahead of print]. PMID: 24375788.

Wang B, Wan JY, Zhang L, et al. Synthetic RGDS peptide attenuates mechanical ventilation-induced lung injury in rats. Exp Lung Res. 2012 May;38(4):204-10. PMID: 22452721.

Zhao M, Wang C, Jiang X, et al. Synthesis of RGD containing peptides and their bioactivities. Prep Biochem Biotechnol. 2002 Nov;32(4):363-80. PMID: 12455829.

Preferred conformations of RGDX tetrapeptides to inhibit the binding of fibrinogen to platelets.

Park HS, Kim C, Kang YK. Biopolymers. 2002 Apr 15;63(5):298-313. PMID: 11877740.

" Not dangerous goods.

LKT R2512 RGD 5 mg 60 Tripeptide, binds cell surface integrins. Arginyl-glycyl-aspartic acid 99896-85-2 ≥95% 346.3 C12H22N6O6 C(CC(C(=O)NCC(=O)NC(CC(=O)O)C(=O)O)N)CN=C(N)N Ambient -20°C "Guo Z, He B, Jin H, et al. Targeting efficiency of RGD-modified nanocarriers with different ligand intervals in response to integrin αvβ3 clustering. Biomaterials. 2014 Apr 30. [Epub ahead of print]. PMID: 24794924.

Li Y, Zheng X, Sun Y, et al. RGD-fatty alcohol-modified docetaxel liposomes improve tumor selectivity in vivo. Int J Pharm. 2014 Apr 4;468(1-2):133-141. [Epub ahead of print]. PMID: 24709214.

Zhao M, Wang C, Jiang X, et al. Synthesis of RGD containing peptides and their bioactivities. Prep Biochem Biotechnol. 2002 Nov;32(4):363-80. PMID: 12455829.

Preferred conformations of RGDX tetrapeptides to inhibit the binding of fibrinogen to platelets.

Park HS, Kim C, Kang YK. Biopolymers. 2002 Apr 15;63(5):298-313. PMID: 11877740.

" Not dangerous goods.

LKT R2512 RGD 10 mg 101.9 Tripeptide, binds cell surface integrins. Arginyl-glycyl-aspartic acid 99896-85-2 ≥95% 346.3 C12H22N6O6 C(CC(C(=O)NCC(=O)NC(CC(=O)O)C(=O)O)N)CN=C(N)N Ambient -20°C "Guo Z, He B, Jin H, et al. Targeting efficiency of RGD-modified nanocarriers with different ligand intervals in response to integrin αvβ3 clustering. Biomaterials. 2014 Apr 30. [Epub ahead of print]. PMID: 24794924.

Li Y, Zheng X, Sun Y, et al. RGD-fatty alcohol-modified docetaxel liposomes improve tumor selectivity in vivo. Int J Pharm. 2014 Apr 4;468(1-2):133-141. [Epub ahead of print]. PMID: 24709214.

Zhao M, Wang C, Jiang X, et al. Synthesis of RGD containing peptides and their bioactivities. Prep Biochem Biotechnol. 2002 Nov;32(4):363-80. PMID: 12455829.

Preferred conformations of RGDX tetrapeptides to inhibit the binding of fibrinogen to platelets.

Park HS, Kim C, Kang YK. Biopolymers. 2002 Apr 15;63(5):298-313. PMID: 11877740.

" Not dangerous goods.

LKT R2512 RGD 25 mg 180 Tripeptide, binds cell surface integrins. Arginyl-glycyl-aspartic acid 99896-85-2 ≥95% 346.3 C12H22N6O6 C(CC(C(=O)NCC(=O)NC(CC(=O)O)C(=O)O)N)CN=C(N)N Ambient -20°C "Guo Z, He B, Jin H, et al. Targeting efficiency of RGD-modified nanocarriers with different ligand intervals in response to integrin αvβ3 clustering. Biomaterials. 2014 Apr 30. [Epub ahead of print]. PMID: 24794924.

Li Y, Zheng X, Sun Y, et al. RGD-fatty alcohol-modified docetaxel liposomes improve tumor selectivity in vivo. Int J Pharm. 2014 Apr 4;468(1-2):133-141. [Epub ahead of print]. PMID: 24709214.

Zhao M, Wang C, Jiang X, et al. Synthesis of RGD containing peptides and their bioactivities. Prep Biochem Biotechnol. 2002 Nov;32(4):363-80. PMID: 12455829.

Preferred conformations of RGDX tetrapeptides to inhibit the binding of fibrinogen to platelets.

Park HS, Kim C, Kang YK. Biopolymers. 2002 Apr 15;63(5):298-313. PMID: 11877740.

" Not dangerous goods.

LKT N1983 Neuropeptide Y (3-36), human 0.5 mg 204.1 Endogenous peptide neurotransmitter, involved in feeding behavior, stress signaling, circadian rhythm; Y1-5 agonist. NPY 150138-78-6 ≥95% 4011.48 C175H269N53O54S Ambient -20°C "Wang Q, Wang M, Whim MD. Neuropeptide y gates a stress-induced, long-lasting plasticity in the sympathetic nervous system. J Neurosci. 2013 Jul 31;33(31):12705-17. PMID: 23904607.

Desai SJ, Upadhya MA, Subhedar NK, et al. NPY mediates reward activity of morphine, via NPY Y1 receptors, in the nucleus accumbens shell. Behav Brain Res. 2013 Jun 15;247:79-91. PMID: 23511250

dos Santos VV, Santos DB, Lach G, et al. Neuropeptide Y (NPY) prevents depressive-like behavior, spatial memory deficits and oxidative stress following amyloid-β (Aβ(1-40)) administration in mice. Behav Brain Res. 2013 May 1;244:107-15. PMID: 23396168

Serova LI, Tillinger A, Alaluf LG, et al. Single intranasal neuropeptide Y infusion attenuates development of PTSD-like symptoms to traumatic stress in rats. Neuroscience. 2013 Apr 16;236:298-312. PMID: 23376740.

Zukowska Z, Pons J, Lee EW, et al. Neuropeptide Y: a new mediator linking sympathetic nerves, blood vessels and immune system? Can J Physiol Pharmacol. 2003 Feb;81(2):89-94. PMID: 12710520.

" Not dangerous goods.

LKT N1983 Neuropeptide Y (3-36), human 1 mg 345.1 Endogenous peptide neurotransmitter, involved in feeding behavior, stress signaling, circadian rhythm; Y1-5 agonist. NPY 150138-78-6 ≥95% 4011.48 C175H269N53O54S Ambient -20°C "Wang Q, Wang M, Whim MD. Neuropeptide y gates a stress-induced, long-lasting plasticity in the sympathetic nervous system. J Neurosci. 2013 Jul 31;33(31):12705-17. PMID: 23904607.

Desai SJ, Upadhya MA, Subhedar NK, et al. NPY mediates reward activity of morphine, via NPY Y1 receptors, in the nucleus accumbens shell. Behav Brain Res. 2013 Jun 15;247:79-91. PMID: 23511250

dos Santos VV, Santos DB, Lach G, et al. Neuropeptide Y (NPY) prevents depressive-like behavior, spatial memory deficits and oxidative stress following amyloid-β (Aβ(1-40)) administration in mice. Behav Brain Res. 2013 May 1;244:107-15. PMID: 23396168

Serova LI, Tillinger A, Alaluf LG, et al. Single intranasal neuropeptide Y infusion attenuates development of PTSD-like symptoms to traumatic stress in rats. Neuroscience. 2013 Apr 16;236:298-312. PMID: 23376740.

Zukowska Z, Pons J, Lee EW, et al. Neuropeptide Y: a new mediator linking sympathetic nerves, blood vessels and immune system? Can J Physiol Pharmacol. 2003 Feb;81(2):89-94. PMID: 12710520.

" Not dangerous goods.

LKT N1983 Neuropeptide Y (3-36), human 2.5 mg 612.4 Endogenous peptide neurotransmitter, involved in feeding behavior, stress signaling, circadian rhythm; Y1-5 agonist. NPY 150138-78-6 ≥95% 4011.48 C175H269N53O54S Ambient -20°C "Wang Q, Wang M, Whim MD. Neuropeptide y gates a stress-induced, long-lasting plasticity in the sympathetic nervous system. J Neurosci. 2013 Jul 31;33(31):12705-17. PMID: 23904607.

Desai SJ, Upadhya MA, Subhedar NK, et al. NPY mediates reward activity of morphine, via NPY Y1 receptors, in the nucleus accumbens shell. Behav Brain Res. 2013 Jun 15;247:79-91. PMID: 23511250

dos Santos VV, Santos DB, Lach G, et al. Neuropeptide Y (NPY) prevents depressive-like behavior, spatial memory deficits and oxidative stress following amyloid-β (Aβ(1-40)) administration in mice. Behav Brain Res. 2013 May 1;244:107-15. PMID: 23396168

Serova LI, Tillinger A, Alaluf LG, et al. Single intranasal neuropeptide Y infusion attenuates development of PTSD-like symptoms to traumatic stress in rats. Neuroscience. 2013 Apr 16;236:298-312. PMID: 23376740.

Zukowska Z, Pons J, Lee EW, et al. Neuropeptide Y: a new mediator linking sympathetic nerves, blood vessels and immune system? Can J Physiol Pharmacol. 2003 Feb;81(2):89-94. PMID: 12710520.

" Not dangerous goods.

LKT N1984 Neuropeptide FF 5 mg 225 Endogenous RF-amide peptide, involved in nociception and cardiovascular regulation; NPFF1/2 agonist. NPFF; Octapeptide F8FA; F-8-F-NH2 99566-27-5 ≥95% 1081.3 C54H76N14O10 CC(C)CC(C(=O)NC(CC1=CC=CC=C1)C(=O)NC(CCC(=O)N)C(=O)N2CCCC2C(=O)NC(CCC(=O)N)C(=O)NC(CCCN=C(N)N)C(=O)NC(CC3=CC=CC=C3)C(=O)N)NC(=O)C(CC4=CC=CC=C4)N Ambient -20°C "Sun YL, Zhang XY, Sun T, et al. The anti-inflammatory potential of neuropeptide FF in vitro and in vivo. Peptides. 2013 Sep;47:124-32. PMID: 23856454.

Jhamandas JH, Goncharuk V. Role of neuropeptide FF in central cardiovascular and neuroendocrine regulation. Front Endocrinol (Lausanne). 2013 Feb 7;4:8. PMID: 23404625.

Li N, Han ZL, Fang Q, et al. Neuropeptide FF and related peptides attenuates warm-, but not cold-water swim stress-induced analgesia in mice. Behav Brain Res. 2012 Aug 1;233(2):428-33. PMID: 22659392.

" Not dangerous goods.

LKT N1984 Neuropeptide FF 10 mg 384 Endogenous RF-amide peptide, involved in nociception and cardiovascular regulation; NPFF1/2 agonist. NPFF; Octapeptide F8FA; F-8-F-NH2 99566-27-5 ≥95% 1081.3 C54H76N14O10 CC(C)CC(C(=O)NC(CC1=CC=CC=C1)C(=O)NC(CCC(=O)N)C(=O)N2CCCC2C(=O)NC(CCC(=O)N)C(=O)NC(CCCN=C(N)N)C(=O)NC(CC3=CC=CC=C3)C(=O)N)NC(=O)C(CC4=CC=CC=C4)N Ambient -20°C "Sun YL, Zhang XY, Sun T, et al. The anti-inflammatory potential of neuropeptide FF in vitro and in vivo. Peptides. 2013 Sep;47:124-32. PMID: 23856454.

Jhamandas JH, Goncharuk V. Role of neuropeptide FF in central cardiovascular and neuroendocrine regulation. Front Endocrinol (Lausanne). 2013 Feb 7;4:8. PMID: 23404625.

Li N, Han ZL, Fang Q, et al. Neuropeptide FF and related peptides attenuates warm-, but not cold-water swim stress-induced analgesia in mice. Behav Brain Res. 2012 Aug 1;233(2):428-33. PMID: 22659392.

" Not dangerous goods.

LKT N1984 Neuropeptide FF 25 mg 675.2 Endogenous RF-amide peptide, involved in nociception and cardiovascular regulation; NPFF1/2 agonist. NPFF; Octapeptide F8FA; F-8-F-NH2 99566-27-5 ≥95% 1081.3 C54H76N14O10 CC(C)CC(C(=O)NC(CC1=CC=CC=C1)C(=O)NC(CCC(=O)N)C(=O)N2CCCC2C(=O)NC(CCC(=O)N)C(=O)NC(CCCN=C(N)N)C(=O)NC(CC3=CC=CC=C3)C(=O)N)NC(=O)C(CC4=CC=CC=C4)N Ambient -20°C "Sun YL, Zhang XY, Sun T, et al. The anti-inflammatory potential of neuropeptide FF in vitro and in vivo. Peptides. 2013 Sep;47:124-32. PMID: 23856454.

Jhamandas JH, Goncharuk V. Role of neuropeptide FF in central cardiovascular and neuroendocrine regulation. Front Endocrinol (Lausanne). 2013 Feb 7;4:8. PMID: 23404625.

Li N, Han ZL, Fang Q, et al. Neuropeptide FF and related peptides attenuates warm-, but not cold-water swim stress-induced analgesia in mice. Behav Brain Res. 2012 Aug 1;233(2):428-33. PMID: 22659392.

" Not dangerous goods.

LKT N1985 Neuropeptide K, pig 5 mg 960 Endogenous peptide, N-terminal-extended neurokinin A analog; NK2 agonist. neurokinin K ≥95% 5980.6 C175H284N52O52S Ambient -20°C "Prall BC, Cline MA. Anorexigenic effects of central neuropeptide K are associated with hypothalamic changes in juvenile Gallus gallus. Gen Comp Endocrinol. 2008 Nov-Dec;159(2-3):130-5. PMID: 18786538.

Dike A, Cowsik SM. Three-dimensional structure of neuropeptide k bound to dodecylphosphocholine micelles. Biochemistry. 2006 Mar 7;45(9):2994-3004. PMID: 16503654.

"

LKT N1985 Neuropeptide K, pig 10 mg 1632.1 Endogenous peptide, N-terminal-extended neurokinin A analog; NK2 agonist. neurokinin K ≥95% 5980.6 C175H284N52O52S Ambient -20°C "Prall BC, Cline MA. Anorexigenic effects of central neuropeptide K are associated with hypothalamic changes in juvenile Gallus gallus. Gen Comp Endocrinol. 2008 Nov-Dec;159(2-3):130-5. PMID: 18786538.

Dike A, Cowsik SM. Three-dimensional structure of neuropeptide k bound to dodecylphosphocholine micelles. Biochemistry. 2006 Mar 7;45(9):2994-3004. PMID: 16503654.

"

LKT N1985 Neuropeptide K, pig 25 mg 2880.3 Endogenous peptide, N-terminal-extended neurokinin A analog; NK2 agonist. neurokinin K ≥95% 5980.6 C175H284N52O52S Ambient -20°C "Prall BC, Cline MA. Anorexigenic effects of central neuropeptide K are associated with hypothalamic changes in juvenile Gallus gallus. Gen Comp Endocrinol. 2008 Nov-Dec;159(2-3):130-5. PMID: 18786538.

Dike A, Cowsik SM. Three-dimensional structure of neuropeptide k bound to dodecylphosphocholine micelles. Biochemistry. 2006 Mar 7;45(9):2994-3004. PMID: 16503654.

"

LKT R2511 RGDC 5 mg 60 Peptide, used to study cell-surface binding; potential integrin inhibitor. ≥95% 448.48 C15H26N7O7S1 Ambient -20°C "Moon C, Han JR, Park HJ, et al. Synthetic RGDS peptide attenuates lipopolysaccharide-induced pulmonary inflammation by inhibiting integrin signaled MAP kinase pathways. Respir Res. 2009 Mar 9;10:18. PMID: 19272161.

Xiao SJ, Textor M, Spencer ND, et al. Immobilization of the cell-adhesive peptide Arg-Gly-Asp-Cys (RGDC) on titanium surfaces by covalent chemical attachment. J Mater Sci Mater Med. 1997 Dec;8(12):867-72. PMID: 15348806.

" Not dangerous goods.

LKT R2511 RGDC 10 mg 101.9 Peptide, used to study cell-surface binding; potential integrin inhibitor. ≥95% 448.48 C15H26N7O7S1 Ambient -20°C "Moon C, Han JR, Park HJ, et al. Synthetic RGDS peptide attenuates lipopolysaccharide-induced pulmonary inflammation by inhibiting integrin signaled MAP kinase pathways. Respir Res. 2009 Mar 9;10:18. PMID: 19272161.

Xiao SJ, Textor M, Spencer ND, et al. Immobilization of the cell-adhesive peptide Arg-Gly-Asp-Cys (RGDC) on titanium surfaces by covalent chemical attachment. J Mater Sci Mater Med. 1997 Dec;8(12):867-72. PMID: 15348806.

" Not dangerous goods.

LKT R2511 RGDC 25 mg 180 Peptide, used to study cell-surface binding; potential integrin inhibitor. ≥95% 448.48 C15H26N7O7S1 Ambient -20°C "Moon C, Han JR, Park HJ, et al. Synthetic RGDS peptide attenuates lipopolysaccharide-induced pulmonary inflammation by inhibiting integrin signaled MAP kinase pathways. Respir Res. 2009 Mar 9;10:18. PMID: 19272161.

Xiao SJ, Textor M, Spencer ND, et al. Immobilization of the cell-adhesive peptide Arg-Gly-Asp-Cys (RGDC) on titanium surfaces by covalent chemical attachment. J Mater Sci Mater Med. 1997 Dec;8(12):867-72. PMID: 15348806.

" Not dangerous goods.

LKT N1986 Neuropeptide Y, human/rat 5 mg 960 Endogenous peptide neurotransmitter, involved in feeding behavior, stress signaling, circadian rhythm; Y1-5 agonist. ≥95% 4271.7 C189H285N55O57S Ambient -20°C "Wang Q, Wang M, Whim MD. Neuropeptide y gates a stress-induced, long-lasting plasticity in the sympathetic nervous system. J Neurosci. 2013 Jul 31;33(31):12705-17. PMID: 23904607.

Desai SJ, Upadhya MA, Subhedar NK, et al. NPY mediates reward activity of morphine, via NPY Y1 receptors, in the nucleus accumbens shell. Behav Brain Res. 2013 Jun 15;247:79-91. PMID: 23511250

dos Santos VV, Santos DB, Lach G, et al. Neuropeptide Y (NPY) prevents depressive-like behavior, spatial memory deficits and oxidative stress following amyloid-β (Aβ(1-40)) administration in mice. Behav Brain Res. 2013 May 1;244:107-15. PMID: 23396168

Serova LI, Tillinger A, Alaluf LG, et al. Single intranasal neuropeptide Y infusion attenuates development of PTSD-like symptoms to traumatic stress in rats. Neuroscience. 2013 Apr 16;236:298-312. PMID: 23376740.

Zukowska Z, Pons J, Lee EW, et al. Neuropeptide Y: a new mediator linking sympathetic nerves, blood vessels and immune system? Can J Physiol Pharmacol. 2003 Feb;81(2):89-94. PMID: 12710520.

" Not dangerous goods.

LKT N1986 Neuropeptide Y, human/rat 10 mg 1632.1 Endogenous peptide neurotransmitter, involved in feeding behavior, stress signaling, circadian rhythm; Y1-5 agonist. ≥95% 4271.7 C189H285N55O57S Ambient -20°C "Wang Q, Wang M, Whim MD. Neuropeptide y gates a stress-induced, long-lasting plasticity in the sympathetic nervous system. J Neurosci. 2013 Jul 31;33(31):12705-17. PMID: 23904607.

Desai SJ, Upadhya MA, Subhedar NK, et al. NPY mediates reward activity of morphine, via NPY Y1 receptors, in the nucleus accumbens shell. Behav Brain Res. 2013 Jun 15;247:79-91. PMID: 23511250

dos Santos VV, Santos DB, Lach G, et al. Neuropeptide Y (NPY) prevents depressive-like behavior, spatial memory deficits and oxidative stress following amyloid-β (Aβ(1-40)) administration in mice. Behav Brain Res. 2013 May 1;244:107-15. PMID: 23396168

Serova LI, Tillinger A, Alaluf LG, et al. Single intranasal neuropeptide Y infusion attenuates development of PTSD-like symptoms to traumatic stress in rats. Neuroscience. 2013 Apr 16;236:298-312. PMID: 23376740.

Zukowska Z, Pons J, Lee EW, et al. Neuropeptide Y: a new mediator linking sympathetic nerves, blood vessels and immune system? Can J Physiol Pharmacol. 2003 Feb;81(2):89-94. PMID: 12710520.

" Not dangerous goods.

LKT N1986 Neuropeptide Y, human/rat 25 mg 2880.3 Endogenous peptide neurotransmitter, involved in feeding behavior, stress signaling, circadian rhythm; Y1-5 agonist. ≥95% 4271.7 C189H285N55O57S Ambient -20°C "Wang Q, Wang M, Whim MD. Neuropeptide y gates a stress-induced, long-lasting plasticity in the sympathetic nervous system. J Neurosci. 2013 Jul 31;33(31):12705-17. PMID: 23904607.

Desai SJ, Upadhya MA, Subhedar NK, et al. NPY mediates reward activity of morphine, via NPY Y1 receptors, in the nucleus accumbens shell. Behav Brain Res. 2013 Jun 15;247:79-91. PMID: 23511250

dos Santos VV, Santos DB, Lach G, et al. Neuropeptide Y (NPY) prevents depressive-like behavior, spatial memory deficits and oxidative stress following amyloid-β (Aβ(1-40)) administration in mice. Behav Brain Res. 2013 May 1;244:107-15. PMID: 23396168

Serova LI, Tillinger A, Alaluf LG, et al. Single intranasal neuropeptide Y infusion attenuates development of PTSD-like symptoms to traumatic stress in rats. Neuroscience. 2013 Apr 16;236:298-312. PMID: 23376740.

Zukowska Z, Pons J, Lee EW, et al. Neuropeptide Y: a new mediator linking sympathetic nerves, blood vessels and immune system? Can J Physiol Pharmacol. 2003 Feb;81(2):89-94. PMID: 12710520.

" Not dangerous goods.

LKT R2510 RGD-4C 1 mg 216.1 Peptide, used to deliver conjugated drugs to cells; potential αvβ3 and αvβ5 integrin inhibitor. ≥95% 1145.29 C42H60N14O16S4 Ambient -20°C "Allaume X, El-Andaloussi N, Leuchs B, et al. Retargeting of rat parvovirus H-1PV to cancer cells through genetic engineering of the viral capsid. J Virol. 2012 Apr;86(7):3452-65. PMID: 22258256.

Pesonen S, Diaconu I, Cerullo V, et al. Integrin targeted oncolytic adenoviruses Ad5-D24-RGD and Ad5-RGD-D24-GMCSF for treatment of patients with advanced chemotherapy refractory solid tumors. Int J Cancer. 2012 Apr 15;130(8):1937-47. PMID: 21630267.

Sarkioja M, Kanerva A, Salo J, et al. Noninvasive imaging for evaluation of the systemic delivery of capsid-modified adenoviruses in an orthotopic model of advanced lung cancer. Cancer. 2006 Oct 1;107(7):1578-88. PMID: 16948124.

Van Houdt WJ, Haviv YS, Lu B, et al. The human survivin promoter: a novel transcriptional targeting strategy for treatment of glioma. J Neurosurg. 2006 Apr;104(4):583-92. PMID: 16619663.

"

LKT R2510 RGD-4C 2 mg 365.9 Peptide, used to deliver conjugated drugs to cells; potential αvβ3 and αvβ5 integrin inhibitor. ≥95% 1145.29 C42H60N14O16S4 Ambient -20°C "Allaume X, El-Andaloussi N, Leuchs B, et al. Retargeting of rat parvovirus H-1PV to cancer cells through genetic engineering of the viral capsid. J Virol. 2012 Apr;86(7):3452-65. PMID: 22258256.

Pesonen S, Diaconu I, Cerullo V, et al. Integrin targeted oncolytic adenoviruses Ad5-D24-RGD and Ad5-RGD-D24-GMCSF for treatment of patients with advanced chemotherapy refractory solid tumors. Int J Cancer. 2012 Apr 15;130(8):1937-47. PMID: 21630267.

Sarkioja M, Kanerva A, Salo J, et al. Noninvasive imaging for evaluation of the systemic delivery of capsid-modified adenoviruses in an orthotopic model of advanced lung cancer. Cancer. 2006 Oct 1;107(7):1578-88. PMID: 16948124.

Van Houdt WJ, Haviv YS, Lu B, et al. The human survivin promoter: a novel transcriptional targeting strategy for treatment of glioma. J Neurosurg. 2006 Apr;104(4):583-92. PMID: 16619663.

"

LKT R2510 RGD-4C 5 mg 648.2 Peptide, used to deliver conjugated drugs to cells; potential αvβ3 and αvβ5 integrin inhibitor. ≥95% 1145.29 C42H60N14O16S4 Ambient -20°C "Allaume X, El-Andaloussi N, Leuchs B, et al. Retargeting of rat parvovirus H-1PV to cancer cells through genetic engineering of the viral capsid. J Virol. 2012 Apr;86(7):3452-65. PMID: 22258256.

Pesonen S, Diaconu I, Cerullo V, et al. Integrin targeted oncolytic adenoviruses Ad5-D24-RGD and Ad5-RGD-D24-GMCSF for treatment of patients with advanced chemotherapy refractory solid tumors. Int J Cancer. 2012 Apr 15;130(8):1937-47. PMID: 21630267.

Sarkioja M, Kanerva A, Salo J, et al. Noninvasive imaging for evaluation of the systemic delivery of capsid-modified adenoviruses in an orthotopic model of advanced lung cancer. Cancer. 2006 Oct 1;107(7):1578-88. PMID: 16948124.

Van Houdt WJ, Haviv YS, Lu B, et al. The human survivin promoter: a novel transcriptional targeting strategy for treatment of glioma. J Neurosurg. 2006 Apr;104(4):583-92. PMID: 16619663.

"

LKT N1987 Neuropeptide Y (13-36), human 0.5 mg 183 Endogenous peptide neurotransmitter, involved in feeding behavior, stress signaling, circadian rhythm; Y1-5 agonist. NPY 122341-40-6 ≥95% 3000.46 C134H207N41O36S Ambient -20°C "Wang Q, Wang M, Whim MD. Neuropeptide y gates a stress-induced, long-lasting plasticity in the sympathetic nervous system. J Neurosci. 2013 Jul 31;33(31):12705-17. PMID: 23904607.

Desai SJ, Upadhya MA, Subhedar NK, et al. NPY mediates reward activity of morphine, via NPY Y1 receptors, in the nucleus accumbens shell. Behav Brain Res. 2013 Jun 15;247:79-91. PMID: 23511250

dos Santos VV, Santos DB, Lach G, et al. Neuropeptide Y (NPY) prevents depressive-like behavior, spatial memory deficits and oxidative stress following amyloid-β (Aβ(1-40)) administration in mice. Behav Brain Res. 2013 May 1;244:107-15. PMID: 23396168

Serova LI, Tillinger A, Alaluf LG, et al. Single intranasal neuropeptide Y infusion attenuates development of PTSD-like symptoms to traumatic stress in rats. Neuroscience. 2013 Apr 16;236:298-312. PMID: 23376740.

Zukowska Z, Pons J, Lee EW, et al. Neuropeptide Y: a new mediator linking sympathetic nerves, blood vessels and immune system? Can J Physiol Pharmacol. 2003 Feb;81(2):89-94. PMID: 12710520.

" Not dangerous goods.

LKT N1987 Neuropeptide Y (13-36), human 1 mg 306.1 Endogenous peptide neurotransmitter, involved in feeding behavior, stress signaling, circadian rhythm; Y1-5 agonist. NPY 122341-40-6 ≥95% 3000.46 C134H207N41O36S Ambient -20°C "Wang Q, Wang M, Whim MD. Neuropeptide y gates a stress-induced, long-lasting plasticity in the sympathetic nervous system. J Neurosci. 2013 Jul 31;33(31):12705-17. PMID: 23904607.

Desai SJ, Upadhya MA, Subhedar NK, et al. NPY mediates reward activity of morphine, via NPY Y1 receptors, in the nucleus accumbens shell. Behav Brain Res. 2013 Jun 15;247:79-91. PMID: 23511250

dos Santos VV, Santos DB, Lach G, et al. Neuropeptide Y (NPY) prevents depressive-like behavior, spatial memory deficits and oxidative stress following amyloid-β (Aβ(1-40)) administration in mice. Behav Brain Res. 2013 May 1;244:107-15. PMID: 23396168

Serova LI, Tillinger A, Alaluf LG, et al. Single intranasal neuropeptide Y infusion attenuates development of PTSD-like symptoms to traumatic stress in rats. Neuroscience. 2013 Apr 16;236:298-312. PMID: 23376740.

Zukowska Z, Pons J, Lee EW, et al. Neuropeptide Y: a new mediator linking sympathetic nerves, blood vessels and immune system? Can J Physiol Pharmacol. 2003 Feb;81(2):89-94. PMID: 12710520.

" Not dangerous goods.

LKT N1987 Neuropeptide Y (13-36), human 2.5 mg 540 Endogenous peptide neurotransmitter, involved in feeding behavior, stress signaling, circadian rhythm; Y1-5 agonist. NPY 122341-40-6 ≥95% 3000.46 C134H207N41O36S Ambient -20°C "Wang Q, Wang M, Whim MD. Neuropeptide y gates a stress-induced, long-lasting plasticity in the sympathetic nervous system. J Neurosci. 2013 Jul 31;33(31):12705-17. PMID: 23904607.

Desai SJ, Upadhya MA, Subhedar NK, et al. NPY mediates reward activity of morphine, via NPY Y1 receptors, in the nucleus accumbens shell. Behav Brain Res. 2013 Jun 15;247:79-91. PMID: 23511250

dos Santos VV, Santos DB, Lach G, et al. Neuropeptide Y (NPY) prevents depressive-like behavior, spatial memory deficits and oxidative stress following amyloid-β (Aβ(1-40)) administration in mice. Behav Brain Res. 2013 May 1;244:107-15. PMID: 23396168

Serova LI, Tillinger A, Alaluf LG, et al. Single intranasal neuropeptide Y infusion attenuates development of PTSD-like symptoms to traumatic stress in rats. Neuroscience. 2013 Apr 16;236:298-312. PMID: 23376740.

Zukowska Z, Pons J, Lee EW, et al. Neuropeptide Y: a new mediator linking sympathetic nerves, blood vessels and immune system? Can J Physiol Pharmacol. 2003 Feb;81(2):89-94. PMID: 12710520.

" Not dangerous goods.

LKT N1988 γ-Neuropeptide, rabbit 0.5 mg 180 Endogenous neuropeptide; NK2 agonist. gamma-neuropeptide 114882-65-4 ≥95% 2320.64 C99H158N34O29S CCC(C)C(C(=O)NC(CO)C(=O)NC(CC1=CN=CN1)C(=O)NC(CCCCN)C(=O)NC(CCCNC(=N)N)C(=O)NC(CC2=CN=CN2)C(=O)NC(CCCCN)C(=O)NC(C(C)O)C(=O)NC(CC(=O)O)C(=O)NC(CO)C(=O)NC(CC3=CC=CC=C3)C(=O)NC(C(C)C)C(=O)NCC(=O)NC(CC(C)C)C(=O)NC(CCSC)C(=O)N)NC(=O)C(CCC(=O)N)NC(=O)CNC(=O)C(CC4=CN=CN4)NC(=O)CNC(=O)C(C)NC(=O)C(CC(=O)O)N Ambient -20°C "Pietruszka M, Jankowska E, Kowalik-Jankowska T, et al. Complexation abilities of neuropeptide gamma toward copper(II) ions and products of metal-catalyzed oxidation. Inorg Chem. 2011 Aug 15;50(16):7489-99. PMID: 21770367.

Kim EJ, Kim CH, Seo JK, et al. Structure-activity relationship of neuropeptide gamma derived from mammalian and fish. J Pept Res. 2005 Dec;66(6):395-403. PMID: 16316456.

Debeljuk L, Lasaga M. Modulation of the hypothalamo-pituitary-gonadal axis and the pineal gland by neurokinin A, neuropeptide K and neuropeptide gamma. Peptides. 1999;20(2):285-99. PMID: 10422885.

Yuan L, Burcher E, Nail BS. Characterization of tachykinin receptors mediating bronchomotor and vasodepressor responses to neuropeptide gamma and substance P in the anaesthetized rabbit. Pulm Pharmacol Ther. 1998 Feb;11(1):31-9. PMID: 9802961.

"

LKT N1988 γ-Neuropeptide, rabbit 1 mg 306.1 Endogenous neuropeptide; NK2 agonist. gamma-neuropeptide 114882-65-4 ≥95% 2320.64 C99H158N34O29S CCC(C)C(C(=O)NC(CO)C(=O)NC(CC1=CN=CN1)C(=O)NC(CCCCN)C(=O)NC(CCCNC(=N)N)C(=O)NC(CC2=CN=CN2)C(=O)NC(CCCCN)C(=O)NC(C(C)O)C(=O)NC(CC(=O)O)C(=O)NC(CO)C(=O)NC(CC3=CC=CC=C3)C(=O)NC(C(C)C)C(=O)NCC(=O)NC(CC(C)C)C(=O)NC(CCSC)C(=O)N)NC(=O)C(CCC(=O)N)NC(=O)CNC(=O)C(CC4=CN=CN4)NC(=O)CNC(=O)C(C)NC(=O)C(CC(=O)O)N Ambient -20°C "Pietruszka M, Jankowska E, Kowalik-Jankowska T, et al. Complexation abilities of neuropeptide gamma toward copper(II) ions and products of metal-catalyzed oxidation. Inorg Chem. 2011 Aug 15;50(16):7489-99. PMID: 21770367.

Kim EJ, Kim CH, Seo JK, et al. Structure-activity relationship of neuropeptide gamma derived from mammalian and fish. J Pept Res. 2005 Dec;66(6):395-403. PMID: 16316456.

Debeljuk L, Lasaga M. Modulation of the hypothalamo-pituitary-gonadal axis and the pineal gland by neurokinin A, neuropeptide K and neuropeptide gamma. Peptides. 1999;20(2):285-99. PMID: 10422885.

Yuan L, Burcher E, Nail BS. Characterization of tachykinin receptors mediating bronchomotor and vasodepressor responses to neuropeptide gamma and substance P in the anaesthetized rabbit. Pulm Pharmacol Ther. 1998 Feb;11(1):31-9. PMID: 9802961.

"

LKT N1988 γ-Neuropeptide, rabbit 2.5 mg 540 Endogenous neuropeptide; NK2 agonist. gamma-neuropeptide 114882-65-4 ≥95% 2320.64 C99H158N34O29S CCC(C)C(C(=O)NC(CO)C(=O)NC(CC1=CN=CN1)C(=O)NC(CCCCN)C(=O)NC(CCCNC(=N)N)C(=O)NC(CC2=CN=CN2)C(=O)NC(CCCCN)C(=O)NC(C(C)O)C(=O)NC(CC(=O)O)C(=O)NC(CO)C(=O)NC(CC3=CC=CC=C3)C(=O)NC(C(C)C)C(=O)NCC(=O)NC(CC(C)C)C(=O)NC(CCSC)C(=O)N)NC(=O)C(CCC(=O)N)NC(=O)CNC(=O)C(CC4=CN=CN4)NC(=O)CNC(=O)C(C)NC(=O)C(CC(=O)O)N Ambient -20°C "Pietruszka M, Jankowska E, Kowalik-Jankowska T, et al. Complexation abilities of neuropeptide gamma toward copper(II) ions and products of metal-catalyzed oxidation. Inorg Chem. 2011 Aug 15;50(16):7489-99. PMID: 21770367.

Kim EJ, Kim CH, Seo JK, et al. Structure-activity relationship of neuropeptide gamma derived from mammalian and fish. J Pept Res. 2005 Dec;66(6):395-403. PMID: 16316456.

Debeljuk L, Lasaga M. Modulation of the hypothalamo-pituitary-gonadal axis and the pineal gland by neurokinin A, neuropeptide K and neuropeptide gamma. Peptides. 1999;20(2):285-99. PMID: 10422885.

Yuan L, Burcher E, Nail BS. Characterization of tachykinin receptors mediating bronchomotor and vasodepressor responses to neuropeptide gamma and substance P in the anaesthetized rabbit. Pulm Pharmacol Ther. 1998 Feb;11(1):31-9. PMID: 9802961.

"

LKT R2369 RFRP-1, human 0.5 mg 72.1 Peptide, avian GnIG analog; GPR147 activator. ≥95% 1428.73 C67H101N19O14S Ambient -20°C "Kovács A, László K, Gálosi R, et al. Microinjection of RFRP-1 in the central nucleus of amygdala decreases food intake in the rat. Brain Res Bull. 2012 Sep 1;88(6):589-95. PMID: 22691952.

Kaewwongse M, Takayanagi Y, Onaka T. Effects of RFamide-related peptide (RFRP)-1 and RFRP-3 on oxytocin release and anxiety-related behaviour in rats. J Neuroendocrinol. 2011 Jan;23(1):20-7. PMID: 21029217.

Clarke IJ, Qi Y, Puspita Sari I, et al. Evidence that RF-amide related peptides are inhibitors of reproduction in mammals. Front Neuroendocrinol. 2009 Aug;30(3):371-8. PMID: 19362107.

" Not dangerous goods.

LKT R2369 RFRP-1, human 1 mg 122.4 Peptide, avian GnIG analog; GPR147 activator. ≥95% 1428.73 C67H101N19O14S Ambient -20°C "Kovács A, László K, Gálosi R, et al. Microinjection of RFRP-1 in the central nucleus of amygdala decreases food intake in the rat. Brain Res Bull. 2012 Sep 1;88(6):589-95. PMID: 22691952.

Kaewwongse M, Takayanagi Y, Onaka T. Effects of RFamide-related peptide (RFRP)-1 and RFRP-3 on oxytocin release and anxiety-related behaviour in rats. J Neuroendocrinol. 2011 Jan;23(1):20-7. PMID: 21029217.

Clarke IJ, Qi Y, Puspita Sari I, et al. Evidence that RF-amide related peptides are inhibitors of reproduction in mammals. Front Neuroendocrinol. 2009 Aug;30(3):371-8. PMID: 19362107.

" Not dangerous goods.

LKT R2369 RFRP-1, human 2.5 mg 216.1 Peptide, avian GnIG analog; GPR147 activator. ≥95% 1428.73 C67H101N19O14S Ambient -20°C "Kovács A, László K, Gálosi R, et al. Microinjection of RFRP-1 in the central nucleus of amygdala decreases food intake in the rat. Brain Res Bull. 2012 Sep 1;88(6):589-95. PMID: 22691952.

Kaewwongse M, Takayanagi Y, Onaka T. Effects of RFamide-related peptide (RFRP)-1 and RFRP-3 on oxytocin release and anxiety-related behaviour in rats. J Neuroendocrinol. 2011 Jan;23(1):20-7. PMID: 21029217.

Clarke IJ, Qi Y, Puspita Sari I, et al. Evidence that RF-amide related peptides are inhibitors of reproduction in mammals. Front Neuroendocrinol. 2009 Aug;30(3):371-8. PMID: 19362107.

" Not dangerous goods.

LKT R2353 RF-NH2 5 mg 60 RF-amide peptide; potential GPR147 agonist, potential acid-sensing ion channel activator. RF amide peptide 34388-59-5 ≥95% 320.4 C15H24N6O2 c1ccc(cc1)CC(C(=O)N)NC(=O)C(CCCNC(=N)N)N Ambient -20°C "Bass C, Katanski C, Maynard B, et al. Conserved residues in RF-NH2 receptor models identify predicted contact sites in ligand-receptor binding. Peptides. 2013 Jun 26. pii: S0196-9781(13)00226-X. [Epub ahead of print]. PMID: 23811075.

Yang HY, Iadarola MJ. Modulatory roles of the NPFF system in pain mechanisms at the spinal level. Peptides. 2006 May;27(5):943-52. PMID: 16443306.

Schiebe M, Orchard I, Watts R, et al. Characterization and partial purification of different factors with contraction-potentiating activities from neurohaemal organs of the locust. J Comp Neurol. 1990 Jan 8;291(2):305-12. PMID: 2298936.

"

LKT R2353 RF-NH2 10 mg 101.9 RF-amide peptide; potential GPR147 agonist, potential acid-sensing ion channel activator. RF amide peptide 34388-59-5 ≥95% 320.4 C15H24N6O2 c1ccc(cc1)CC(C(=O)N)NC(=O)C(CCCNC(=N)N)N Ambient -20°C "Bass C, Katanski C, Maynard B, et al. Conserved residues in RF-NH2 receptor models identify predicted contact sites in ligand-receptor binding. Peptides. 2013 Jun 26. pii: S0196-9781(13)00226-X. [Epub ahead of print]. PMID: 23811075.

Yang HY, Iadarola MJ. Modulatory roles of the NPFF system in pain mechanisms at the spinal level. Peptides. 2006 May;27(5):943-52. PMID: 16443306.

Schiebe M, Orchard I, Watts R, et al. Characterization and partial purification of different factors with contraction-potentiating activities from neurohaemal organs of the locust. J Comp Neurol. 1990 Jan 8;291(2):305-12. PMID: 2298936.

"

LKT R2353 RF-NH2 25 mg 180 RF-amide peptide; potential GPR147 agonist, potential acid-sensing ion channel activator. RF amide peptide 34388-59-5 ≥95% 320.4 C15H24N6O2 c1ccc(cc1)CC(C(=O)N)NC(=O)C(CCCNC(=N)N)N Ambient -20°C "Bass C, Katanski C, Maynard B, et al. Conserved residues in RF-NH2 receptor models identify predicted contact sites in ligand-receptor binding. Peptides. 2013 Jun 26. pii: S0196-9781(13)00226-X. [Epub ahead of print]. PMID: 23811075.

Yang HY, Iadarola MJ. Modulatory roles of the NPFF system in pain mechanisms at the spinal level. Peptides. 2006 May;27(5):943-52. PMID: 16443306.

Schiebe M, Orchard I, Watts R, et al. Characterization and partial purification of different factors with contraction-potentiating activities from neurohaemal organs of the locust. J Comp Neurol. 1990 Jan 8;291(2):305-12. PMID: 2298936.

"

LKT N1989 Neurotensin 1 mg 60 Endogenous neuropeptide involved in hormone release; NTS agonist. 39379-15-2 ≥95% 1672.9 C78H122N21O20 CCC(C)C(C(=O)NC(CC(C)C)C(=O)O)NC(=O)C(CC1=CC=C(C=C1)O)NC(=O)C2CCCN2C(=O)C(CCCN=C(N)N)NC(=O)C(CCCN=C(N)N)NC(=O)C3CCCN3C(=O)C(CCCCN)NC(=O)C(CC(=O)N)NC(=O)C(CCC(=O)O)NC(=O)C(CC4=CC=C(C=C4)O)NC(=O)C(CC(C)C)NC(=O)C5CCC(=O)N5 Ambient -20°C Soluble in water. "Kleczkowska P, Lipkowski AW. Neurotensin and neurotensin receptors: characteristic, structure-activity relationship and pain modulation--a review. Eur J Pharmacol. 2013 Sep 15;716(1-3):54-60. PMID: 23500196.

Degolier TF, Brown DR, Duke GE, et al. Neurotensin and cholecystokinin contract gallbladder circular muscle in chickens. Poult Sci. 2013 Aug;92(8):2156-62. PMID: 23873564.

Furutani N, Hondo M, Kageyama H, et al. Neurotensin co-expressed in orexin-producing neurons in the lateral hypothalamus plays an important role in regulation of sleep/wakefulness states. PLoS One. 2013 Apr 19;8(4):e62391. PMID: 23620827.

Lee J, Kim YD, Park CG, et al. Neurotensin modulates pacemaker activity in interstitial cells of Cajal from the mouse small intestine. Mol Cells. 2012 May;33(5):509-16. PMID: 22441675.

Zogovic B, Pilowsky PM. Intrathecal neurotensin is hypotensive, sympathoinhibitory and enhances the baroreflex in anaesthetized rat. Br J Pharmacol. 2012 May;166(1):378-89. PMID: 22035146.

Law IK, Murphy JE, Bakirtzi K, et al. Neurotensin-induced proinflammatory signaling in human colonocytes is regulated by β-arrestins and endothelin-converting enzyme-1-dependent endocytosis and resensitization of neurotensin receptor 1. J Biol Chem. 2012 Apr 27;287(18):15066-75. PMID: 22416137.

" Not dangerous goods.

LKT N1989 Neurotensin 2 mg 101.9 Endogenous neuropeptide involved in hormone release; NTS agonist. 39379-15-2 ≥95% 1672.9 C78H122N21O20 CCC(C)C(C(=O)NC(CC(C)C)C(=O)O)NC(=O)C(CC1=CC=C(C=C1)O)NC(=O)C2CCCN2C(=O)C(CCCN=C(N)N)NC(=O)C(CCCN=C(N)N)NC(=O)C3CCCN3C(=O)C(CCCCN)NC(=O)C(CC(=O)N)NC(=O)C(CCC(=O)O)NC(=O)C(CC4=CC=C(C=C4)O)NC(=O)C(CC(C)C)NC(=O)C5CCC(=O)N5 Ambient -20°C Soluble in water. "Kleczkowska P, Lipkowski AW. Neurotensin and neurotensin receptors: characteristic, structure-activity relationship and pain modulation--a review. Eur J Pharmacol. 2013 Sep 15;716(1-3):54-60. PMID: 23500196.

Degolier TF, Brown DR, Duke GE, et al. Neurotensin and cholecystokinin contract gallbladder circular muscle in chickens. Poult Sci. 2013 Aug;92(8):2156-62. PMID: 23873564.

Furutani N, Hondo M, Kageyama H, et al. Neurotensin co-expressed in orexin-producing neurons in the lateral hypothalamus plays an important role in regulation of sleep/wakefulness states. PLoS One. 2013 Apr 19;8(4):e62391. PMID: 23620827.

Lee J, Kim YD, Park CG, et al. Neurotensin modulates pacemaker activity in interstitial cells of Cajal from the mouse small intestine. Mol Cells. 2012 May;33(5):509-16. PMID: 22441675.

Zogovic B, Pilowsky PM. Intrathecal neurotensin is hypotensive, sympathoinhibitory and enhances the baroreflex in anaesthetized rat. Br J Pharmacol. 2012 May;166(1):378-89. PMID: 22035146.

Law IK, Murphy JE, Bakirtzi K, et al. Neurotensin-induced proinflammatory signaling in human colonocytes is regulated by β-arrestins and endothelin-converting enzyme-1-dependent endocytosis and resensitization of neurotensin receptor 1. J Biol Chem. 2012 Apr 27;287(18):15066-75. PMID: 22416137.

" Not dangerous goods.

LKT N1989 Neurotensin 5 mg 180 Endogenous neuropeptide involved in hormone release; NTS agonist. 39379-15-2 ≥95% 1672.9 C78H122N21O20 CCC(C)C(C(=O)NC(CC(C)C)C(=O)O)NC(=O)C(CC1=CC=C(C=C1)O)NC(=O)C2CCCN2C(=O)C(CCCN=C(N)N)NC(=O)C(CCCN=C(N)N)NC(=O)C3CCCN3C(=O)C(CCCCN)NC(=O)C(CC(=O)N)NC(=O)C(CCC(=O)O)NC(=O)C(CC4=CC=C(C=C4)O)NC(=O)C(CC(C)C)NC(=O)C5CCC(=O)N5 Ambient -20°C Soluble in water. "Kleczkowska P, Lipkowski AW. Neurotensin and neurotensin receptors: characteristic, structure-activity relationship and pain modulation--a review. Eur J Pharmacol. 2013 Sep 15;716(1-3):54-60. PMID: 23500196.

Degolier TF, Brown DR, Duke GE, et al. Neurotensin and cholecystokinin contract gallbladder circular muscle in chickens. Poult Sci. 2013 Aug;92(8):2156-62. PMID: 23873564.

Furutani N, Hondo M, Kageyama H, et al. Neurotensin co-expressed in orexin-producing neurons in the lateral hypothalamus plays an important role in regulation of sleep/wakefulness states. PLoS One. 2013 Apr 19;8(4):e62391. PMID: 23620827.

Lee J, Kim YD, Park CG, et al. Neurotensin modulates pacemaker activity in interstitial cells of Cajal from the mouse small intestine. Mol Cells. 2012 May;33(5):509-16. PMID: 22441675.

Zogovic B, Pilowsky PM. Intrathecal neurotensin is hypotensive, sympathoinhibitory and enhances the baroreflex in anaesthetized rat. Br J Pharmacol. 2012 May;166(1):378-89. PMID: 22035146.

Law IK, Murphy JE, Bakirtzi K, et al. Neurotensin-induced proinflammatory signaling in human colonocytes is regulated by β-arrestins and endothelin-converting enzyme-1-dependent endocytosis and resensitization of neurotensin receptor 1. J Biol Chem. 2012 Apr 27;287(18):15066-75. PMID: 22416137.

" Not dangerous goods.

LKT N1990 [Gln4]-Neurotensin 5 mg 180 Endogenous neuropeptide involved in hormone release; NTS agonist. 61445-54-3 ≥95% 1671.9 C78H122N22O19 CCC(C)C(C(=O)NC(CC(C)C)C(=O)O)NC(=O)C(CC1=CC=C(C=C1)O)NC(=O)C2CCCN2C(=O)C(CCCN=C(N)N)NC(=O)C(CCCN=C(N)N)NC(=O)C3CCCN3C(=O)C(CCCCN)NC(=O)C(CC(=O)N)NC(=O)C(CCC(=O)N)NC(=O)C(CC4=CC=C(C=C4)O)NC(=O)C(CC(C)C)NC(=O)C5CCC(=O)N5 Ambient -20°C "Kleczkowska P, Lipkowski AW. Neurotensin and neurotensin receptors: characteristic, structure-activity relationship and pain modulation--a review. Eur J Pharmacol. 2013 Sep 15;716(1-3):54-60. PMID: 23500196.

Degolier TF, Brown DR, Duke GE, et al. Neurotensin and cholecystokinin contract gallbladder circular muscle in chickens. Poult Sci. 2013 Aug;92(8):2156-62. PMID: 23873564.

Furutani N, Hondo M, Kageyama H, et al. Neurotensin co-expressed in orexin-producing neurons in the lateral hypothalamus plays an important role in regulation of sleep/wakefulness states. PLoS One. 2013 Apr 19;8(4):e62391. PMID: 23620827.

Lee J, Kim YD, Park CG, et al. Neurotensin modulates pacemaker activity in interstitial cells of Cajal from the mouse small intestine. Mol Cells. 2012 May;33(5):509-16. PMID: 22441675.

Zogovic B, Pilowsky PM. Intrathecal neurotensin is hypotensive, sympathoinhibitory and enhances the baroreflex in anaesthetized rat. Br J Pharmacol. 2012 May;166(1):378-89. PMID: 22035146.

Law IK, Murphy JE, Bakirtzi K, et al. Neurotensin-induced proinflammatory signaling in human colonocytes is regulated by β-arrestins and endothelin-converting enzyme-1-dependent endocytosis and resensitization of neurotensin receptor 1. J Biol Chem. 2012 Apr 27;287(18):15066-75. PMID: 22416137.

" Not dangerous goods.

LKT R2112 RFDS 5 mg 101 RGD peptide negative control. ≥98% 523.5 C22H33N7O8 Ambient -20°C "Iwao Y, Fujimura T. Activation of Xenopus eggs by RGD-containing peptides accompanied by intracellular Ca2+ release. Dev Biol. 1996 Aug 1;177(2):558-67. PMID: 8806831.

Mazerolles F, Durandy A, Piatier-Tonneau D, et al. Immunosuppressive properties of synthetic peptides derived from CD4 and HLA-DR antigens. Cell. 1988 Nov 4;55(3):497-504. PMID: 3263212.

Auffray C, Novotny J. Speculations on sequence homologies between the fibronectin cell-attachment site, major histocompatibility antigens, and a putative AIDS virus polypeptide. Hum Immunol. 1986 Apr;15(4):381-90. PMID: 3009364.

" Not dangerous goods.

LKT N1990 [Gln4]-Neurotensin 2 mg 101.9 Endogenous neuropeptide involved in hormone release; NTS agonist. 61445-54-3 ≥95% 1671.9 C78H122N22O19 CCC(C)C(C(=O)NC(CC(C)C)C(=O)O)NC(=O)C(CC1=CC=C(C=C1)O)NC(=O)C2CCCN2C(=O)C(CCCN=C(N)N)NC(=O)C(CCCN=C(N)N)NC(=O)C3CCCN3C(=O)C(CCCCN)NC(=O)C(CC(=O)N)NC(=O)C(CCC(=O)N)NC(=O)C(CC4=CC=C(C=C4)O)NC(=O)C(CC(C)C)NC(=O)C5CCC(=O)N5 Ambient -20°C "Kleczkowska P, Lipkowski AW. Neurotensin and neurotensin receptors: characteristic, structure-activity relationship and pain modulation--a review. Eur J Pharmacol. 2013 Sep 15;716(1-3):54-60. PMID: 23500196.

Degolier TF, Brown DR, Duke GE, et al. Neurotensin and cholecystokinin contract gallbladder circular muscle in chickens. Poult Sci. 2013 Aug;92(8):2156-62. PMID: 23873564.

Furutani N, Hondo M, Kageyama H, et al. Neurotensin co-expressed in orexin-producing neurons in the lateral hypothalamus plays an important role in regulation of sleep/wakefulness states. PLoS One. 2013 Apr 19;8(4):e62391. PMID: 23620827.

Lee J, Kim YD, Park CG, et al. Neurotensin modulates pacemaker activity in interstitial cells of Cajal from the mouse small intestine. Mol Cells. 2012 May;33(5):509-16. PMID: 22441675.

Zogovic B, Pilowsky PM. Intrathecal neurotensin is hypotensive, sympathoinhibitory and enhances the baroreflex in anaesthetized rat. Br J Pharmacol. 2012 May;166(1):378-89. PMID: 22035146.

Law IK, Murphy JE, Bakirtzi K, et al. Neurotensin-induced proinflammatory signaling in human colonocytes is regulated by β-arrestins and endothelin-converting enzyme-1-dependent endocytosis and resensitization of neurotensin receptor 1. J Biol Chem. 2012 Apr 27;287(18):15066-75. PMID: 22416137.

" Not dangerous goods.

LKT N1990 [Gln4]-Neurotensin 1 mg 60 Endogenous neuropeptide involved in hormone release; NTS agonist. 61445-54-3 ≥95% 1671.9 C78H122N22O19 CCC(C)C(C(=O)NC(CC(C)C)C(=O)O)NC(=O)C(CC1=CC=C(C=C1)O)NC(=O)C2CCCN2C(=O)C(CCCN=C(N)N)NC(=O)C(CCCN=C(N)N)NC(=O)C3CCCN3C(=O)C(CCCCN)NC(=O)C(CC(=O)N)NC(=O)C(CCC(=O)N)NC(=O)C(CC4=CC=C(C=C4)O)NC(=O)C(CC(C)C)NC(=O)C5CCC(=O)N5 Ambient -20°C "Kleczkowska P, Lipkowski AW. Neurotensin and neurotensin receptors: characteristic, structure-activity relationship and pain modulation--a review. Eur J Pharmacol. 2013 Sep 15;716(1-3):54-60. PMID: 23500196.

Degolier TF, Brown DR, Duke GE, et al. Neurotensin and cholecystokinin contract gallbladder circular muscle in chickens. Poult Sci. 2013 Aug;92(8):2156-62. PMID: 23873564.

Furutani N, Hondo M, Kageyama H, et al. Neurotensin co-expressed in orexin-producing neurons in the lateral hypothalamus plays an important role in regulation of sleep/wakefulness states. PLoS One. 2013 Apr 19;8(4):e62391. PMID: 23620827.

Lee J, Kim YD, Park CG, et al. Neurotensin modulates pacemaker activity in interstitial cells of Cajal from the mouse small intestine. Mol Cells. 2012 May;33(5):509-16. PMID: 22441675.

Zogovic B, Pilowsky PM. Intrathecal neurotensin is hypotensive, sympathoinhibitory and enhances the baroreflex in anaesthetized rat. Br J Pharmacol. 2012 May;166(1):378-89. PMID: 22035146.

Law IK, Murphy JE, Bakirtzi K, et al. Neurotensin-induced proinflammatory signaling in human colonocytes is regulated by β-arrestins and endothelin-converting enzyme-1-dependent endocytosis and resensitization of neurotensin receptor 1. J Biol Chem. 2012 Apr 27;287(18):15066-75. PMID: 22416137.

" Not dangerous goods.

LKT N1991 [D-Trp11]-Neurotensin 5 mg 180 Endogenous neuropeptide involved in hormone release; NTS agonist. 75644-95-0 ≥95% 1696 C80H122N22O19 CCC(C)C(C(=O)NC(CC(C)C)C(=O)O)NC(=O)C(CC1=CNC2=CC=CC=C21)NC(=O)C3CCCN3C(=O)C(CCCNC(=N)N)NC(=O)C(CCCNC(=N)N)NC(=O)C4CCCN4C(=O)C(CCCCN)NC(=O)C(CC(=O)N)NC(=O)C(CCC(=O)O)NC(=O)C(CC5=CC=C(C=C5)O)NC(=O)C(CC(C)C)NC(=O)C6CCC(=O)N6 Ambient -20°C "Kleczkowska P, Lipkowski AW. Neurotensin and neurotensin receptors: characteristic, structure-activity relationship and pain modulation--a review. Eur J Pharmacol. 2013 Sep 15;716(1-3):54-60. PMID: 23500196.

Degolier TF, Brown DR, Duke GE, et al. Neurotensin and cholecystokinin contract gallbladder circular muscle in chickens. Poult Sci. 2013 Aug;92(8):2156-62. PMID: 23873564.

Furutani N, Hondo M, Kageyama H, et al. Neurotensin co-expressed in orexin-producing neurons in the lateral hypothalamus plays an important role in regulation of sleep/wakefulness states. PLoS One. 2013 Apr 19;8(4):e62391. PMID: 23620827.

Lee J, Kim YD, Park CG, et al. Neurotensin modulates pacemaker activity in interstitial cells of Cajal from the mouse small intestine. Mol Cells. 2012 May;33(5):509-16. PMID: 22441675.

Zogovic B, Pilowsky PM. Intrathecal neurotensin is hypotensive, sympathoinhibitory and enhances the baroreflex in anaesthetized rat. Br J Pharmacol. 2012 May;166(1):378-89. PMID: 22035146.

Law IK, Murphy JE, Bakirtzi K, et al. Neurotensin-induced proinflammatory signaling in human colonocytes is regulated by β-arrestins and endothelin-converting enzyme-1-dependent endocytosis and resensitization of neurotensin receptor 1. J Biol Chem. 2012 Apr 27;287(18):15066-75. PMID: 22416137.

" Not dangerous goods.

LKT N1991 [D-Trp11]-Neurotensin 10 mg 306.1 Endogenous neuropeptide involved in hormone release; NTS agonist. 75644-95-0 ≥95% 1696 C80H122N22O19 CCC(C)C(C(=O)NC(CC(C)C)C(=O)O)NC(=O)C(CC1=CNC2=CC=CC=C21)NC(=O)C3CCCN3C(=O)C(CCCNC(=N)N)NC(=O)C(CCCNC(=N)N)NC(=O)C4CCCN4C(=O)C(CCCCN)NC(=O)C(CC(=O)N)NC(=O)C(CCC(=O)O)NC(=O)C(CC5=CC=C(C=C5)O)NC(=O)C(CC(C)C)NC(=O)C6CCC(=O)N6 Ambient -20°C "Kleczkowska P, Lipkowski AW. Neurotensin and neurotensin receptors: characteristic, structure-activity relationship and pain modulation--a review. Eur J Pharmacol. 2013 Sep 15;716(1-3):54-60. PMID: 23500196.

Degolier TF, Brown DR, Duke GE, et al. Neurotensin and cholecystokinin contract gallbladder circular muscle in chickens. Poult Sci. 2013 Aug;92(8):2156-62. PMID: 23873564.

Furutani N, Hondo M, Kageyama H, et al. Neurotensin co-expressed in orexin-producing neurons in the lateral hypothalamus plays an important role in regulation of sleep/wakefulness states. PLoS One. 2013 Apr 19;8(4):e62391. PMID: 23620827.

Lee J, Kim YD, Park CG, et al. Neurotensin modulates pacemaker activity in interstitial cells of Cajal from the mouse small intestine. Mol Cells. 2012 May;33(5):509-16. PMID: 22441675.

Zogovic B, Pilowsky PM. Intrathecal neurotensin is hypotensive, sympathoinhibitory and enhances the baroreflex in anaesthetized rat. Br J Pharmacol. 2012 May;166(1):378-89. PMID: 22035146.

Law IK, Murphy JE, Bakirtzi K, et al. Neurotensin-induced proinflammatory signaling in human colonocytes is regulated by β-arrestins and endothelin-converting enzyme-1-dependent endocytosis and resensitization of neurotensin receptor 1. J Biol Chem. 2012 Apr 27;287(18):15066-75. PMID: 22416137.

" Not dangerous goods.

LKT N1991 [D-Trp11]-Neurotensin 25 mg 540 Endogenous neuropeptide involved in hormone release; NTS agonist. 75644-95-0 ≥95% 1696 C80H122N22O19 CCC(C)C(C(=O)NC(CC(C)C)C(=O)O)NC(=O)C(CC1=CNC2=CC=CC=C21)NC(=O)C3CCCN3C(=O)C(CCCNC(=N)N)NC(=O)C(CCCNC(=N)N)NC(=O)C4CCCN4C(=O)C(CCCCN)NC(=O)C(CC(=O)N)NC(=O)C(CCC(=O)O)NC(=O)C(CC5=CC=C(C=C5)O)NC(=O)C(CC(C)C)NC(=O)C6CCC(=O)N6 Ambient -20°C "Kleczkowska P, Lipkowski AW. Neurotensin and neurotensin receptors: characteristic, structure-activity relationship and pain modulation--a review. Eur J Pharmacol. 2013 Sep 15;716(1-3):54-60. PMID: 23500196.

Degolier TF, Brown DR, Duke GE, et al. Neurotensin and cholecystokinin contract gallbladder circular muscle in chickens. Poult Sci. 2013 Aug;92(8):2156-62. PMID: 23873564.

Furutani N, Hondo M, Kageyama H, et al. Neurotensin co-expressed in orexin-producing neurons in the lateral hypothalamus plays an important role in regulation of sleep/wakefulness states. PLoS One. 2013 Apr 19;8(4):e62391. PMID: 23620827.

Lee J, Kim YD, Park CG, et al. Neurotensin modulates pacemaker activity in interstitial cells of Cajal from the mouse small intestine. Mol Cells. 2012 May;33(5):509-16. PMID: 22441675.

Zogovic B, Pilowsky PM. Intrathecal neurotensin is hypotensive, sympathoinhibitory and enhances the baroreflex in anaesthetized rat. Br J Pharmacol. 2012 May;166(1):378-89. PMID: 22035146.

Law IK, Murphy JE, Bakirtzi K, et al. Neurotensin-induced proinflammatory signaling in human colonocytes is regulated by β-arrestins and endothelin-converting enzyme-1-dependent endocytosis and resensitization of neurotensin receptor 1. J Biol Chem. 2012 Apr 27;287(18):15066-75. PMID: 22416137.

" Not dangerous goods.

LKT N1992 Neurotensin (1-11) 1 mg 60 Endogenous neuropeptide involved in hormone release; NTS agonist. 74032-89-6 ≥95% 1446.66 C66H99N19O18 CC(C)CC(C(=O)NC(CC1=CC=C(C=C1)O)C(=O)NC(CCC(=O)O)C(=O)NC(CC(=O)N)C(=O)NC(CCCCN)C(=O)N2CCCC2C(=O)NC(CCCN=C(N)N)C(=O)NC(CCCN=C(N)N)C(=O)N3CCCC3C(=O)NC(CC4=CC=C(C=C4)O)C(=O)O)NC(=O)C5CCC(=O)N5 Ambient -20°C "Kleczkowska P, Lipkowski AW. Neurotensin and neurotensin receptors: characteristic, structure-activity relationship and pain modulation--a review. Eur J Pharmacol. 2013 Sep 15;716(1-3):54-60. PMID: 23500196.

Degolier TF, Brown DR, Duke GE, et al. Neurotensin and cholecystokinin contract gallbladder circular muscle in chickens. Poult Sci. 2013 Aug;92(8):2156-62. PMID: 23873564.

Furutani N, Hondo M, Kageyama H, et al. Neurotensin co-expressed in orexin-producing neurons in the lateral hypothalamus plays an important role in regulation of sleep/wakefulness states. PLoS One. 2013 Apr 19;8(4):e62391. PMID: 23620827.

Lee J, Kim YD, Park CG, et al. Neurotensin modulates pacemaker activity in interstitial cells of Cajal from the mouse small intestine. Mol Cells. 2012 May;33(5):509-16. PMID: 22441675.

Zogovic B, Pilowsky PM. Intrathecal neurotensin is hypotensive, sympathoinhibitory and enhances the baroreflex in anaesthetized rat. Br J Pharmacol. 2012 May;166(1):378-89. PMID: 22035146.

Law IK, Murphy JE, Bakirtzi K, et al. Neurotensin-induced proinflammatory signaling in human colonocytes is regulated by β-arrestins and endothelin-converting enzyme-1-dependent endocytosis and resensitization of neurotensin receptor 1. J Biol Chem. 2012 Apr 27;287(18):15066-75. PMID: 22416137.

" Not dangerous goods.

LKT N1992 Neurotensin (1-11) 2 mg 101.9 Endogenous neuropeptide involved in hormone release; NTS agonist. 74032-89-6 ≥95% 1446.66 C66H99N19O18 CC(C)CC(C(=O)NC(CC1=CC=C(C=C1)O)C(=O)NC(CCC(=O)O)C(=O)NC(CC(=O)N)C(=O)NC(CCCCN)C(=O)N2CCCC2C(=O)NC(CCCN=C(N)N)C(=O)NC(CCCN=C(N)N)C(=O)N3CCCC3C(=O)NC(CC4=CC=C(C=C4)O)C(=O)O)NC(=O)C5CCC(=O)N5 Ambient -20°C "Kleczkowska P, Lipkowski AW. Neurotensin and neurotensin receptors: characteristic, structure-activity relationship and pain modulation--a review. Eur J Pharmacol. 2013 Sep 15;716(1-3):54-60. PMID: 23500196.

Degolier TF, Brown DR, Duke GE, et al. Neurotensin and cholecystokinin contract gallbladder circular muscle in chickens. Poult Sci. 2013 Aug;92(8):2156-62. PMID: 23873564.

Furutani N, Hondo M, Kageyama H, et al. Neurotensin co-expressed in orexin-producing neurons in the lateral hypothalamus plays an important role in regulation of sleep/wakefulness states. PLoS One. 2013 Apr 19;8(4):e62391. PMID: 23620827.

Lee J, Kim YD, Park CG, et al. Neurotensin modulates pacemaker activity in interstitial cells of Cajal from the mouse small intestine. Mol Cells. 2012 May;33(5):509-16. PMID: 22441675.

Zogovic B, Pilowsky PM. Intrathecal neurotensin is hypotensive, sympathoinhibitory and enhances the baroreflex in anaesthetized rat. Br J Pharmacol. 2012 May;166(1):378-89. PMID: 22035146.

Law IK, Murphy JE, Bakirtzi K, et al. Neurotensin-induced proinflammatory signaling in human colonocytes is regulated by β-arrestins and endothelin-converting enzyme-1-dependent endocytosis and resensitization of neurotensin receptor 1. J Biol Chem. 2012 Apr 27;287(18):15066-75. PMID: 22416137.

" Not dangerous goods.

LKT N1992 Neurotensin (1-11) 5 mg 180 Endogenous neuropeptide involved in hormone release; NTS agonist. 74032-89-6 ≥95% 1446.66 C66H99N19O18 CC(C)CC(C(=O)NC(CC1=CC=C(C=C1)O)C(=O)NC(CCC(=O)O)C(=O)NC(CC(=O)N)C(=O)NC(CCCCN)C(=O)N2CCCC2C(=O)NC(CCCN=C(N)N)C(=O)NC(CCCN=C(N)N)C(=O)N3CCCC3C(=O)NC(CC4=CC=C(C=C4)O)C(=O)O)NC(=O)C5CCC(=O)N5 Ambient -20°C "Kleczkowska P, Lipkowski AW. Neurotensin and neurotensin receptors: characteristic, structure-activity relationship and pain modulation--a review. Eur J Pharmacol. 2013 Sep 15;716(1-3):54-60. PMID: 23500196.

Degolier TF, Brown DR, Duke GE, et al. Neurotensin and cholecystokinin contract gallbladder circular muscle in chickens. Poult Sci. 2013 Aug;92(8):2156-62. PMID: 23873564.

Furutani N, Hondo M, Kageyama H, et al. Neurotensin co-expressed in orexin-producing neurons in the lateral hypothalamus plays an important role in regulation of sleep/wakefulness states. PLoS One. 2013 Apr 19;8(4):e62391. PMID: 23620827.

Lee J, Kim YD, Park CG, et al. Neurotensin modulates pacemaker activity in interstitial cells of Cajal from the mouse small intestine. Mol Cells. 2012 May;33(5):509-16. PMID: 22441675.

Zogovic B, Pilowsky PM. Intrathecal neurotensin is hypotensive, sympathoinhibitory and enhances the baroreflex in anaesthetized rat. Br J Pharmacol. 2012 May;166(1):378-89. PMID: 22035146.

Law IK, Murphy JE, Bakirtzi K, et al. Neurotensin-induced proinflammatory signaling in human colonocytes is regulated by β-arrestins and endothelin-converting enzyme-1-dependent endocytosis and resensitization of neurotensin receptor 1. J Biol Chem. 2012 Apr 27;287(18):15066-75. PMID: 22416137.

" Not dangerous goods.

LKT N1993 Neurotensin (9-13) 5 mg 180 Endogenous neuropeptide involved in hormone release; NTS agonist. ≥95% 660.82 C32H52N8O7 Ambient -20°C "Kleczkowska P, Lipkowski AW. Neurotensin and neurotensin receptors: characteristic, structure-activity relationship and pain modulation--a review. Eur J Pharmacol. 2013 Sep 15;716(1-3):54-60. PMID: 23500196.

Degolier TF, Brown DR, Duke GE, et al. Neurotensin and cholecystokinin contract gallbladder circular muscle in chickens. Poult Sci. 2013 Aug;92(8):2156-62. PMID: 23873564.

Furutani N, Hondo M, Kageyama H, et al. Neurotensin co-expressed in orexin-producing neurons in the lateral hypothalamus plays an important role in regulation of sleep/wakefulness states. PLoS One. 2013 Apr 19;8(4):e62391. PMID: 23620827.

Lee J, Kim YD, Park CG, et al. Neurotensin modulates pacemaker activity in interstitial cells of Cajal from the mouse small intestine. Mol Cells. 2012 May;33(5):509-16. PMID: 22441675.

Zogovic B, Pilowsky PM. Intrathecal neurotensin is hypotensive, sympathoinhibitory and enhances the baroreflex in anaesthetized rat. Br J Pharmacol. 2012 May;166(1):378-89. PMID: 22035146.

Law IK, Murphy JE, Bakirtzi K, et al. Neurotensin-induced proinflammatory signaling in human colonocytes is regulated by β-arrestins and endothelin-converting enzyme-1-dependent endocytosis and resensitization of neurotensin receptor 1. J Biol Chem. 2012 Apr 27;287(18):15066-75. PMID: 22416137.

" Not dangerous goods.

LKT N1993 Neurotensin (9-13) 10 mg 306.1 Endogenous neuropeptide involved in hormone release; NTS agonist. ≥95% 660.82 C32H52N8O7 Ambient -20°C "Kleczkowska P, Lipkowski AW. Neurotensin and neurotensin receptors: characteristic, structure-activity relationship and pain modulation--a review. Eur J Pharmacol. 2013 Sep 15;716(1-3):54-60. PMID: 23500196.

Degolier TF, Brown DR, Duke GE, et al. Neurotensin and cholecystokinin contract gallbladder circular muscle in chickens. Poult Sci. 2013 Aug;92(8):2156-62. PMID: 23873564.

Furutani N, Hondo M, Kageyama H, et al. Neurotensin co-expressed in orexin-producing neurons in the lateral hypothalamus plays an important role in regulation of sleep/wakefulness states. PLoS One. 2013 Apr 19;8(4):e62391. PMID: 23620827.

Lee J, Kim YD, Park CG, et al. Neurotensin modulates pacemaker activity in interstitial cells of Cajal from the mouse small intestine. Mol Cells. 2012 May;33(5):509-16. PMID: 22441675.

Zogovic B, Pilowsky PM. Intrathecal neurotensin is hypotensive, sympathoinhibitory and enhances the baroreflex in anaesthetized rat. Br J Pharmacol. 2012 May;166(1):378-89. PMID: 22035146.

Law IK, Murphy JE, Bakirtzi K, et al. Neurotensin-induced proinflammatory signaling in human colonocytes is regulated by β-arrestins and endothelin-converting enzyme-1-dependent endocytosis and resensitization of neurotensin receptor 1. J Biol Chem. 2012 Apr 27;287(18):15066-75. PMID: 22416137.

" Not dangerous goods.

LKT N1993 Neurotensin (9-13) 25 mg 540 Endogenous neuropeptide involved in hormone release; NTS agonist. ≥95% 660.82 C32H52N8O7 Ambient -20°C "Kleczkowska P, Lipkowski AW. Neurotensin and neurotensin receptors: characteristic, structure-activity relationship and pain modulation--a review. Eur J Pharmacol. 2013 Sep 15;716(1-3):54-60. PMID: 23500196.

Degolier TF, Brown DR, Duke GE, et al. Neurotensin and cholecystokinin contract gallbladder circular muscle in chickens. Poult Sci. 2013 Aug;92(8):2156-62. PMID: 23873564.

Furutani N, Hondo M, Kageyama H, et al. Neurotensin co-expressed in orexin-producing neurons in the lateral hypothalamus plays an important role in regulation of sleep/wakefulness states. PLoS One. 2013 Apr 19;8(4):e62391. PMID: 23620827.

Lee J, Kim YD, Park CG, et al. Neurotensin modulates pacemaker activity in interstitial cells of Cajal from the mouse small intestine. Mol Cells. 2012 May;33(5):509-16. PMID: 22441675.

Zogovic B, Pilowsky PM. Intrathecal neurotensin is hypotensive, sympathoinhibitory and enhances the baroreflex in anaesthetized rat. Br J Pharmacol. 2012 May;166(1):378-89. PMID: 22035146.

Law IK, Murphy JE, Bakirtzi K, et al. Neurotensin-induced proinflammatory signaling in human colonocytes is regulated by β-arrestins and endothelin-converting enzyme-1-dependent endocytosis and resensitization of neurotensin receptor 1. J Biol Chem. 2012 Apr 27;287(18):15066-75. PMID: 22416137.

" Not dangerous goods.

LKT N1994 Neurotensin, frog 0.5 mg 36 Endogenous neuropeptide involved in hormone release; NTS agonist. ≥95% 1550.84 C70H115N23O17 Ambient -20°C "Kleczkowska P, Lipkowski AW. Neurotensin and neurotensin receptors: characteristic, structure-activity relationship and pain modulation--a review. Eur J Pharmacol. 2013 Sep 15;716(1-3):54-60. PMID: 23500196.

Degolier TF, Brown DR, Duke GE, et al. Neurotensin and cholecystokinin contract gallbladder circular muscle in chickens. Poult Sci. 2013 Aug;92(8):2156-62. PMID: 23873564.

Furutani N, Hondo M, Kageyama H, et al. Neurotensin co-expressed in orexin-producing neurons in the lateral hypothalamus plays an important role in regulation of sleep/wakefulness states. PLoS One. 2013 Apr 19;8(4):e62391. PMID: 23620827.

Lee J, Kim YD, Park CG, et al. Neurotensin modulates pacemaker activity in interstitial cells of Cajal from the mouse small intestine. Mol Cells. 2012 May;33(5):509-16. PMID: 22441675.

Zogovic B, Pilowsky PM. Intrathecal neurotensin is hypotensive, sympathoinhibitory and enhances the baroreflex in anaesthetized rat. Br J Pharmacol. 2012 May;166(1):378-89. PMID: 22035146.

Law IK, Murphy JE, Bakirtzi K, et al. Neurotensin-induced proinflammatory signaling in human colonocytes is regulated by β-arrestins and endothelin-converting enzyme-1-dependent endocytosis and resensitization of neurotensin receptor 1. J Biol Chem. 2012 Apr 27;287(18):15066-75. PMID: 22416137.

" Not dangerous goods.

LKT N1994 Neurotensin, frog 1 mg 60 Endogenous neuropeptide involved in hormone release; NTS agonist. ≥95% 1550.84 C70H115N23O17 Ambient -20°C "Kleczkowska P, Lipkowski AW. Neurotensin and neurotensin receptors: characteristic, structure-activity relationship and pain modulation--a review. Eur J Pharmacol. 2013 Sep 15;716(1-3):54-60. PMID: 23500196.

Degolier TF, Brown DR, Duke GE, et al. Neurotensin and cholecystokinin contract gallbladder circular muscle in chickens. Poult Sci. 2013 Aug;92(8):2156-62. PMID: 23873564.

Furutani N, Hondo M, Kageyama H, et al. Neurotensin co-expressed in orexin-producing neurons in the lateral hypothalamus plays an important role in regulation of sleep/wakefulness states. PLoS One. 2013 Apr 19;8(4):e62391. PMID: 23620827.

Lee J, Kim YD, Park CG, et al. Neurotensin modulates pacemaker activity in interstitial cells of Cajal from the mouse small intestine. Mol Cells. 2012 May;33(5):509-16. PMID: 22441675.

Zogovic B, Pilowsky PM. Intrathecal neurotensin is hypotensive, sympathoinhibitory and enhances the baroreflex in anaesthetized rat. Br J Pharmacol. 2012 May;166(1):378-89. PMID: 22035146.

Law IK, Murphy JE, Bakirtzi K, et al. Neurotensin-induced proinflammatory signaling in human colonocytes is regulated by β-arrestins and endothelin-converting enzyme-1-dependent endocytosis and resensitization of neurotensin receptor 1. J Biol Chem. 2012 Apr 27;287(18):15066-75. PMID: 22416137.

" Not dangerous goods.

LKT N1994 Neurotensin, frog 2.5 mg 107.8 Endogenous neuropeptide involved in hormone release; NTS agonist. ≥95% 1550.84 C70H115N23O17 Ambient -20°C "Kleczkowska P, Lipkowski AW. Neurotensin and neurotensin receptors: characteristic, structure-activity relationship and pain modulation--a review. Eur J Pharmacol. 2013 Sep 15;716(1-3):54-60. PMID: 23500196.

Degolier TF, Brown DR, Duke GE, et al. Neurotensin and cholecystokinin contract gallbladder circular muscle in chickens. Poult Sci. 2013 Aug;92(8):2156-62. PMID: 23873564.

Furutani N, Hondo M, Kageyama H, et al. Neurotensin co-expressed in orexin-producing neurons in the lateral hypothalamus plays an important role in regulation of sleep/wakefulness states. PLoS One. 2013 Apr 19;8(4):e62391. PMID: 23620827.

Lee J, Kim YD, Park CG, et al. Neurotensin modulates pacemaker activity in interstitial cells of Cajal from the mouse small intestine. Mol Cells. 2012 May;33(5):509-16. PMID: 22441675.

Zogovic B, Pilowsky PM. Intrathecal neurotensin is hypotensive, sympathoinhibitory and enhances the baroreflex in anaesthetized rat. Br J Pharmacol. 2012 May;166(1):378-89. PMID: 22035146.

Law IK, Murphy JE, Bakirtzi K, et al. Neurotensin-induced proinflammatory signaling in human colonocytes is regulated by β-arrestins and endothelin-converting enzyme-1-dependent endocytosis and resensitization of neurotensin receptor 1. J Biol Chem. 2012 Apr 27;287(18):15066-75. PMID: 22416137.

" Not dangerous goods.

LKT N1995 Neurotensin, guinea pig 5 mg 180 Endogenous neuropeptide involved in hormone release; NTS agonist. ≥95% 1662.92 C76H119N21O21 Ambient -20°C "Kleczkowska P, Lipkowski AW. Neurotensin and neurotensin receptors: characteristic, structure-activity relationship and pain modulation--a review. Eur J Pharmacol. 2013 Sep 15;716(1-3):54-60. PMID: 23500196.

Degolier TF, Brown DR, Duke GE, et al. Neurotensin and cholecystokinin contract gallbladder circular muscle in chickens. Poult Sci. 2013 Aug;92(8):2156-62. PMID: 23873564.

Furutani N, Hondo M, Kageyama H, et al. Neurotensin co-expressed in orexin-producing neurons in the lateral hypothalamus plays an important role in regulation of sleep/wakefulness states. PLoS One. 2013 Apr 19;8(4):e62391. PMID: 23620827.

Lee J, Kim YD, Park CG, et al. Neurotensin modulates pacemaker activity in interstitial cells of Cajal from the mouse small intestine. Mol Cells. 2012 May;33(5):509-16. PMID: 22441675.

Zogovic B, Pilowsky PM. Intrathecal neurotensin is hypotensive, sympathoinhibitory and enhances the baroreflex in anaesthetized rat. Br J Pharmacol. 2012 May;166(1):378-89. PMID: 22035146.

Law IK, Murphy JE, Bakirtzi K, et al. Neurotensin-induced proinflammatory signaling in human colonocytes is regulated by β-arrestins and endothelin-converting enzyme-1-dependent endocytosis and resensitization of neurotensin receptor 1. J Biol Chem. 2012 Apr 27;287(18):15066-75. PMID: 22416137.

" Not dangerous goods.

LKT N1995 Neurotensin, guinea pig 2 mg 101.9 Endogenous neuropeptide involved in hormone release; NTS agonist. ≥95% 1662.92 C76H119N21O21 Ambient -20°C "Kleczkowska P, Lipkowski AW. Neurotensin and neurotensin receptors: characteristic, structure-activity relationship and pain modulation--a review. Eur J Pharmacol. 2013 Sep 15;716(1-3):54-60. PMID: 23500196.

Degolier TF, Brown DR, Duke GE, et al. Neurotensin and cholecystokinin contract gallbladder circular muscle in chickens. Poult Sci. 2013 Aug;92(8):2156-62. PMID: 23873564.

Furutani N, Hondo M, Kageyama H, et al. Neurotensin co-expressed in orexin-producing neurons in the lateral hypothalamus plays an important role in regulation of sleep/wakefulness states. PLoS One. 2013 Apr 19;8(4):e62391. PMID: 23620827.

Lee J, Kim YD, Park CG, et al. Neurotensin modulates pacemaker activity in interstitial cells of Cajal from the mouse small intestine. Mol Cells. 2012 May;33(5):509-16. PMID: 22441675.

Zogovic B, Pilowsky PM. Intrathecal neurotensin is hypotensive, sympathoinhibitory and enhances the baroreflex in anaesthetized rat. Br J Pharmacol. 2012 May;166(1):378-89. PMID: 22035146.

Law IK, Murphy JE, Bakirtzi K, et al. Neurotensin-induced proinflammatory signaling in human colonocytes is regulated by β-arrestins and endothelin-converting enzyme-1-dependent endocytosis and resensitization of neurotensin receptor 1. J Biol Chem. 2012 Apr 27;287(18):15066-75. PMID: 22416137.

" Not dangerous goods.

LKT N1995 Neurotensin, guinea pig 1 mg 60 Endogenous neuropeptide involved in hormone release; NTS agonist. ≥95% 1662.92 C76H119N21O21 Ambient -20°C "Kleczkowska P, Lipkowski AW. Neurotensin and neurotensin receptors: characteristic, structure-activity relationship and pain modulation--a review. Eur J Pharmacol. 2013 Sep 15;716(1-3):54-60. PMID: 23500196.

Degolier TF, Brown DR, Duke GE, et al. Neurotensin and cholecystokinin contract gallbladder circular muscle in chickens. Poult Sci. 2013 Aug;92(8):2156-62. PMID: 23873564.

Furutani N, Hondo M, Kageyama H, et al. Neurotensin co-expressed in orexin-producing neurons in the lateral hypothalamus plays an important role in regulation of sleep/wakefulness states. PLoS One. 2013 Apr 19;8(4):e62391. PMID: 23620827.

Lee J, Kim YD, Park CG, et al. Neurotensin modulates pacemaker activity in interstitial cells of Cajal from the mouse small intestine. Mol Cells. 2012 May;33(5):509-16. PMID: 22441675.

Zogovic B, Pilowsky PM. Intrathecal neurotensin is hypotensive, sympathoinhibitory and enhances the baroreflex in anaesthetized rat. Br J Pharmacol. 2012 May;166(1):378-89. PMID: 22035146.

Law IK, Murphy JE, Bakirtzi K, et al. Neurotensin-induced proinflammatory signaling in human colonocytes is regulated by β-arrestins and endothelin-converting enzyme-1-dependent endocytosis and resensitization of neurotensin receptor 1. J Biol Chem. 2012 Apr 27;287(18):15066-75. PMID: 22416137.

" Not dangerous goods.

LKT N3213 Nidulal 0.5 mg 509.7 Sesquiterpene found in Nidula. ≥95% 276.28 C15H16O5 CC1=CC2(C(=O)C(=CO2)C3CCC(CC3)C=O)OC1=O Protect from light. Ambient -20°C Soluble in ethanol, methanol or DMSO. Erkel G, Becker U, Anke T, et al. Nidulal, a novel inducer of differentiation of human promyelocytic leukemia cells from Nidula candida. J Antibiot (Tokyo). 1996 Dec;49(12):1189-95. PMID: 9031663. Not dangerous goods.

LKT R1879 Retinyl Palmitate 25 g 35.4 Vitamin A derivative, palmitic acid ester of retinol. >1.70 MIU/g, bio assay Vitamin A palmitate; Retinyl hexadecanoate; Aquasol A 79-81-2 ≥1.70 MIU/g, bio assay 524.86 C36H60O2 CCCCCCCCCCCCCCCC(=O)OCC=C(C)C=CC=C(C)C=CC1=C(CCCC1(C)C)C Ambient 4°C Insoluble in water. "Park EY, Pinali D, Lindley K, et al. Hepatic vitamin A preloading reduces colorectal cancer metastatic multiplicity in a mouse xenograft model. Nutr Cancer. 2012;64(5):732-40. PMID: 22642873.

Mei N, Xia Q, Chen L, et al. Photomutagenicity of retinyl palmitate by ultraviolet a irradiation in mouse lymphoma cells. Toxicol Sci. 2005 Nov;88(1):142-9. PMID: 16107546.

Maziere S, Cassand P, Narbonne JF, et al. Vitamin A and apoptosis in colonic tumor cells. Int J Vitam Nutr Res. 1997;67(4):237-41. PMID: 9285252.

Livrea MA, Tesoriere L, Bongiorno A, et al. Contribution of vitamin A to the oxidation resistance of human low density lipoproteins. Free Radic Biol Med. 1995 Mar;18(3):401-9. PMID: 9101230.

" Repr., T, Xn Not dangerous goods.

LKT R1879 Retinyl Palmitate 100 g 96.6 Vitamin A derivative, palmitic acid ester of retinol. >1.70 MIU/g, bio assay Vitamin A palmitate; Retinyl hexadecanoate; Aquasol A 79-81-2 ≥1.70 MIU/g, bio assay 524.86 C36H60O2 CCCCCCCCCCCCCCCC(=O)OCC=C(C)C=CC=C(C)C=CC1=C(CCCC1(C)C)C Ambient 4°C Insoluble in water. "Park EY, Pinali D, Lindley K, et al. Hepatic vitamin A preloading reduces colorectal cancer metastatic multiplicity in a mouse xenograft model. Nutr Cancer. 2012;64(5):732-40. PMID: 22642873.

Mei N, Xia Q, Chen L, et al. Photomutagenicity of retinyl palmitate by ultraviolet a irradiation in mouse lymphoma cells. Toxicol Sci. 2005 Nov;88(1):142-9. PMID: 16107546.

Maziere S, Cassand P, Narbonne JF, et al. Vitamin A and apoptosis in colonic tumor cells. Int J Vitam Nutr Res. 1997;67(4):237-41. PMID: 9285252.

Livrea MA, Tesoriere L, Bongiorno A, et al. Contribution of vitamin A to the oxidation resistance of human low density lipoproteins. Free Radic Biol Med. 1995 Mar;18(3):401-9. PMID: 9101230.

" Repr., T, Xn Not dangerous goods.

LKT N3225 Nigericin Sodium 1 mg 37.5 Polyether cationic ionophore. Antibiotic K 178 Sodium salt Azalomycin M; Helixin C; Polyetherin A. 28643-80-3 ≥98% 746.94 C40H67O11Na CC1CCC(OC1C(C)C(=O)[O-])CC2CC(C(C3(O2)C(CC(O3)(C)C4CCC(O4)(C)C5C(CC(O5)C6C(CC(C(O6)(CO)O)C)C)C)C)C)OC.[Na+] Ambient 4°C Soluble in chloroform. Practically insoluble in water. "Heid ME, Keyel PA, Kamga C, et al. Mitochondrial reactive oxygen species induces NLRP3-dependent lysosomal damage and inflammasome activation. J Immunol. 2013 Nov 15;191(10):5230-8. PMID: 24089192.

Myskiw C, Piper J, Huzarewich R, et al. Nigericin is a potent inhibitor of the early stage of vaccinia virus replication. Antiviral Res. 2010 Dec;88(3):304-10. PMID: 20951746.

" T Xi "UN number: 3462     Class: 6.1     Packing Group: III

Proper shipping name: Toxins, extracted from living sources, solid, n.o.s. (Nigericin Sodium)"

LKT N3225 Nigericin Sodium 5 mg 91.2 Polyether cationic ionophore. Antibiotic K 178 Sodium salt Azalomycin M; Helixin C; Polyetherin A. 28643-80-3 ≥98% 746.94 C40H67O11Na CC1CCC(OC1C(C)C(=O)[O-])CC2CC(C(C3(O2)C(CC(O3)(C)C4CCC(O4)(C)C5C(CC(O5)C6C(CC(C(O6)(CO)O)C)C)C)C)C)OC.[Na+] Ambient 4°C Soluble in chloroform. Practically insoluble in water. "Heid ME, Keyel PA, Kamga C, et al. Mitochondrial reactive oxygen species induces NLRP3-dependent lysosomal damage and inflammasome activation. J Immunol. 2013 Nov 15;191(10):5230-8. PMID: 24089192.

Myskiw C, Piper J, Huzarewich R, et al. Nigericin is a potent inhibitor of the early stage of vaccinia virus replication. Antiviral Res. 2010 Dec;88(3):304-10. PMID: 20951746.

" T Xi "UN number: 3462     Class: 6.1     Packing Group: III

Proper shipping name: Toxins, extracted from living sources, solid, n.o.s. (Nigericin Sodium)"

LKT N3225 Nigericin Sodium 10 mg 170.5 Polyether cationic ionophore. Antibiotic K 178 Sodium salt Azalomycin M; Helixin C; Polyetherin A. 28643-80-3 ≥98% 746.94 C40H67O11Na CC1CCC(OC1C(C)C(=O)[O-])CC2CC(C(C3(O2)C(CC(O3)(C)C4CCC(O4)(C)C5C(CC(O5)C6C(CC(C(O6)(CO)O)C)C)C)C)C)OC.[Na+] Ambient 4°C Soluble in chloroform. Practically insoluble in water. "Heid ME, Keyel PA, Kamga C, et al. Mitochondrial reactive oxygen species induces NLRP3-dependent lysosomal damage and inflammasome activation. J Immunol. 2013 Nov 15;191(10):5230-8. PMID: 24089192.

Myskiw C, Piper J, Huzarewich R, et al. Nigericin is a potent inhibitor of the early stage of vaccinia virus replication. Antiviral Res. 2010 Dec;88(3):304-10. PMID: 20951746.

" T Xi "UN number: 3462     Class: 6.1     Packing Group: III

Proper shipping name: Toxins, extracted from living sources, solid, n.o.s. (Nigericin Sodium)"

LKT R1878 Retinyl Acetate 5 g 72.2 Vitamin A derivative, acetate ester of retinol. Vitamin A acetate; all-trans-Retinol acetate; Myvak 127-47-9 ≥96% 328.49 C22H32O2 CC1=C(C(CCC1)(C)C)C=CC(=CC=CC(=CCOC(=O)C)C)C Ambient 4°C Soluble in ethanol. "Chiamenti A, Filho CR, Moura MT, et al. Use of retinyl acetate, retinoic acid and insulin-like growth factor-I (IGF-I) to enhance goat embryo production. Acta Vet Hung. 2013 Mar;61(1):116-24. PMID: 23439296.

Greenstein RJ, Su L, Brown ST. Vitamins A & D inhibit the growth of mycobacteria in radiometric culture. PLoS One. 2012;7(1):e29631. PMID: 22235314.

Zhang L, Ren X, Alt E, et al. Chemoprevention of colorectal cancer by targeting APC-deficient cells for apoptosis. Nature. 2010 Apr 15;464(7291):1058-61. PMID: 20348907.

Zunino SJ, Storms DH, Stephensen CB. Diets rich in polyphenols and vitamin A inhibit the development of type I autoimmune diabetes in nonobese diabetic mice. J Nutr. 2007 May;137(5):1216-21. PMID: 17449584.

Hill TD, Boynton AL, Dean NM, et al. Retinyl acetate inhibits platelet-derived growth factor-induced Ca2+ signals in C3H 10T1/2 fibroblasts. J Cell Physiol. 1990 Aug;144(2):229-36. PMID: 2380253.

" Xn Not dangerous goods.

LKT R1878 Retinyl Acetate 25 g 218.4 Vitamin A derivative, acetate ester of retinol. Vitamin A acetate; all-trans-Retinol acetate; Myvak 127-47-9 ≥96% 328.49 C22H32O2 CC1=C(C(CCC1)(C)C)C=CC(=CC=CC(=CCOC(=O)C)C)C Ambient 4°C Soluble in ethanol. "Chiamenti A, Filho CR, Moura MT, et al. Use of retinyl acetate, retinoic acid and insulin-like growth factor-I (IGF-I) to enhance goat embryo production. Acta Vet Hung. 2013 Mar;61(1):116-24. PMID: 23439296.

Greenstein RJ, Su L, Brown ST. Vitamins A & D inhibit the growth of mycobacteria in radiometric culture. PLoS One. 2012;7(1):e29631. PMID: 22235314.

Zhang L, Ren X, Alt E, et al. Chemoprevention of colorectal cancer by targeting APC-deficient cells for apoptosis. Nature. 2010 Apr 15;464(7291):1058-61. PMID: 20348907.

Zunino SJ, Storms DH, Stephensen CB. Diets rich in polyphenols and vitamin A inhibit the development of type I autoimmune diabetes in nonobese diabetic mice. J Nutr. 2007 May;137(5):1216-21. PMID: 17449584.

Hill TD, Boynton AL, Dean NM, et al. Retinyl acetate inhibits platelet-derived growth factor-induced Ca2+ signals in C3H 10T1/2 fibroblasts. J Cell Physiol. 1990 Aug;144(2):229-36. PMID: 2380253.

" Xn Not dangerous goods.

LKT R1878 Retinyl Acetate 100 g 630.6 Vitamin A derivative, acetate ester of retinol. Vitamin A acetate; all-trans-Retinol acetate; Myvak 127-47-9 ≥96% 328.49 C22H32O2 CC1=C(C(CCC1)(C)C)C=CC(=CC=CC(=CCOC(=O)C)C)C Ambient 4°C Soluble in ethanol. "Chiamenti A, Filho CR, Moura MT, et al. Use of retinyl acetate, retinoic acid and insulin-like growth factor-I (IGF-I) to enhance goat embryo production. Acta Vet Hung. 2013 Mar;61(1):116-24. PMID: 23439296.

Greenstein RJ, Su L, Brown ST. Vitamins A & D inhibit the growth of mycobacteria in radiometric culture. PLoS One. 2012;7(1):e29631. PMID: 22235314.

Zhang L, Ren X, Alt E, et al. Chemoprevention of colorectal cancer by targeting APC-deficient cells for apoptosis. Nature. 2010 Apr 15;464(7291):1058-61. PMID: 20348907.

Zunino SJ, Storms DH, Stephensen CB. Diets rich in polyphenols and vitamin A inhibit the development of type I autoimmune diabetes in nonobese diabetic mice. J Nutr. 2007 May;137(5):1216-21. PMID: 17449584.

Hill TD, Boynton AL, Dean NM, et al. Retinyl acetate inhibits platelet-derived growth factor-induced Ca2+ signals in C3H 10T1/2 fibroblasts. J Cell Physiol. 1990 Aug;144(2):229-36. PMID: 2380253.

" Xn Not dangerous goods.

LKT N3228 Nifedipine 1 g 57.8 Dihydropyridine; L-type Ca2+ channel blocker. "1,4-Dihydro-2,6-dimethyl-4-(2-nitrophenyl)-3,5-

pyridinedicarboxylic acid dimethyl ester" Adalat; Anifed; Aprical; Cordipin; Corotrend; Fenihidine; Nifedicor; Nifensar; Orix; Procardia; Sepamit; Zenusin    21829-25-4 ≥98% 346.33 C17H18N2O6 CC1=C(C(C(=C(N1)C)C(=O)OC)C2=CC=CC=C2[N+](=O)[O-])C(=O)OC Sensitive to light while in solution. Ambient Ambient Soluble in DMSO, acetone (100 mg/mL) or ethanol. Insoluble in water. "Gáspár R, Hajagos-Tóth J. Calcium channel blockers as tocolytics: principles of their actions, adverse effects and therapeutic combinations. Pharmaceuticals (Basel). 2013 May 23;6(6):689-99. PMID: 24276256.

Martín MI, del Val VL, Colado MI, et al. Behavioral and analgesic effects induced by administration of nifedipine and nimodipine. Pharmacol Biochem Behav. 1996 Sep;55(1):93-8. PMID: 8870043.

Zsotér TT, Church JG. Calcium antagonists. Pharmacodynamic effects and mechanism of action.  Drugs. 1983 Feb;25(2):93-112. PMID: 6131809.

" Xn, Xi Not dangerous goods.

LKT N3228 Nifedipine 5 g 149.9 Dihydropyridine; L-type Ca2+ channel blocker. "1,4-Dihydro-2,6-dimethyl-4-(2-nitrophenyl)-3,5-

pyridinedicarboxylic acid dimethyl ester" Adalat; Anifed; Aprical; Cordipin; Corotrend; Fenihidine; Nifedicor; Nifensar; Orix; Procardia; Sepamit; Zenusin    21829-25-4 ≥98% 346.33 C17H18N2O6 CC1=C(C(C(=C(N1)C)C(=O)OC)C2=CC=CC=C2[N+](=O)[O-])C(=O)OC Sensitive to light while in solution. Ambient Ambient Soluble in DMSO, acetone (100 mg/mL) or ethanol. Insoluble in water. "Gáspár R, Hajagos-Tóth J. Calcium channel blockers as tocolytics: principles of their actions, adverse effects and therapeutic combinations. Pharmaceuticals (Basel). 2013 May 23;6(6):689-99. PMID: 24276256.

Martín MI, del Val VL, Colado MI, et al. Behavioral and analgesic effects induced by administration of nifedipine and nimodipine. Pharmacol Biochem Behav. 1996 Sep;55(1):93-8. PMID: 8870043.

Zsotér TT, Church JG. Calcium antagonists. Pharmacodynamic effects and mechanism of action.  Drugs. 1983 Feb;25(2):93-112. PMID: 6131809.

" Xn, Xi Not dangerous goods.

LKT N3228 Nifedipine 25 g 432.3 Dihydropyridine; L-type Ca2+ channel blocker. "1,4-Dihydro-2,6-dimethyl-4-(2-nitrophenyl)-3,5-

pyridinedicarboxylic acid dimethyl ester" Adalat; Anifed; Aprical; Cordipin; Corotrend; Fenihidine; Nifedicor; Nifensar; Orix; Procardia; Sepamit; Zenusin    21829-25-4 ≥98% 346.33 C17H18N2O6 CC1=C(C(C(=C(N1)C)C(=O)OC)C2=CC=CC=C2[N+](=O)[O-])C(=O)OC Sensitive to light while in solution. Ambient Ambient Soluble in DMSO, acetone (100 mg/mL) or ethanol. Insoluble in water. "Gáspár R, Hajagos-Tóth J. Calcium channel blockers as tocolytics: principles of their actions, adverse effects and therapeutic combinations. Pharmaceuticals (Basel). 2013 May 23;6(6):689-99. PMID: 24276256.

Martín MI, del Val VL, Colado MI, et al. Behavioral and analgesic effects induced by administration of nifedipine and nimodipine. Pharmacol Biochem Behav. 1996 Sep;55(1):93-8. PMID: 8870043.

Zsotér TT, Church JG. Calcium antagonists. Pharmacodynamic effects and mechanism of action.  Drugs. 1983 Feb;25(2):93-112. PMID: 6131809.

" Xn, Xi Not dangerous goods.

LKT R1876 all-trans-Retinol 100 mg 61.1 Diterpene component of vitamin A, differentiation inducer; RAR and RXR agonist. 3,7-Dimethyl-9-(2,6,6-trimethyl-1-cyclchexen-1-yl)-2,- 4,6,8-nonatetraen-1-ol Alphasterol; Retinol; Avitol; Vitamin A 68-26-8 ≥95% 286.45 C20H30O CC1=C(C(CCC1)(C)C)C=CC(=CC=CC(=CCO)C)C Blue Ice -20°C Soluble in alcohol, methanol, chloroform, ether, fats or oils. "Friedman MD, Jeevan DS, Tobias M, et al. Targeting cancer stem cells in glioblastoma multiforme using mTOR inhibitors and the differentiating agent all-trans retinoic acid. Oncol Rep. 2013 Oct;30(4):1645-50. PMID: 23877261.

Farhangi MA, Keshavarz SA, Eshraghian M, et al. Vitamin a supplementation and serum Th1- and th2-associated cytokine response in women. J Am Coll Nutr. 2013 Aug;32(4):280-5. PMID: 24024773.

Sharma RB, Wang Q, Khillan JS. Amplification of tumor inducing putative cancer stem cells (CSCs) by vitamin A/retinol from mammary tumors. Biochem Biophys Res Commun. 2013 Jul 12;436(4):625-31. PMID: 23764401.

Zhan XX, Liu Y, Yang JF, et al. All-trans-retinoic acid ameliorates experimental allergic encephalomyelitis by affecting dendritic cell and monocyte development. Immunology. 2013 Apr;138(4):333-45. PMID: 23181351.

Duester G. Retinoic acid synthesis and signaling during early organogenesis. Cell. 2008 Sep 19;134(6):921-31. PMID: 18805086.

" Xn Not dangerous goods.

LKT R1876 all-trans-Retinol 250 mg 136 Diterpene component of vitamin A, differentiation inducer; RAR and RXR agonist. 3,7-Dimethyl-9-(2,6,6-trimethyl-1-cyclchexen-1-yl)-2,- 4,6,8-nonatetraen-1-ol Alphasterol; Retinol; Avitol; Vitamin A 68-26-8 ≥95% 286.45 C20H30O CC1=C(C(CCC1)(C)C)C=CC(=CC=CC(=CCO)C)C Blue Ice -20°C Soluble in alcohol, methanol, chloroform, ether, fats or oils. "Friedman MD, Jeevan DS, Tobias M, et al. Targeting cancer stem cells in glioblastoma multiforme using mTOR inhibitors and the differentiating agent all-trans retinoic acid. Oncol Rep. 2013 Oct;30(4):1645-50. PMID: 23877261.

Farhangi MA, Keshavarz SA, Eshraghian M, et al. Vitamin a supplementation and serum Th1- and th2-associated cytokine response in women. J Am Coll Nutr. 2013 Aug;32(4):280-5. PMID: 24024773.

Sharma RB, Wang Q, Khillan JS. Amplification of tumor inducing putative cancer stem cells (CSCs) by vitamin A/retinol from mammary tumors. Biochem Biophys Res Commun. 2013 Jul 12;436(4):625-31. PMID: 23764401.

Zhan XX, Liu Y, Yang JF, et al. All-trans-retinoic acid ameliorates experimental allergic encephalomyelitis by affecting dendritic cell and monocyte development. Immunology. 2013 Apr;138(4):333-45. PMID: 23181351.

Duester G. Retinoic acid synthesis and signaling during early organogenesis. Cell. 2008 Sep 19;134(6):921-31. PMID: 18805086.

" Xn Not dangerous goods.

LKT N3276 Nitroso(acetoxymethyl)methylamine 10 mg 140.7 NNK precursor found in tobacco smoke; carcinogen. Acetoxymethyl methylnitrosamine Methyl(acetoxymethyl)nitrosamine; α-Acetoxy dimethylnitrosamine 56856-83-8 ≥98% 132.12 C4H8N2O3 CC(=O)OCN(C)N=O Ambient -20°C Soluble in water. "Proulx LI, Gaudreault M, Turmel V, et al. 4-(Methylnitrosamino)-1-(3-pyridyl)-1-butanone, a component of tobacco smoke, modulates mediator release from human bronchial and alveolar epithelial cells. Clin Exp Immunol. 2005 Apr;140(1):46-53. PMID: 15762874.

Cloutier JF, Drouin R, Castonguay A. Treatment of human cells with N-Nitroso(acetoxymethyl)methylamine: distribution patterns of piperidine-sensitive DNA damage at the nucleotide level of resolution are related to the sequence context. Chem Res Toxicol. 1999 Sep;12(9):840-9. PMID: 10490506.

Klein RG, Schmezer P, Komitowski D. Carcinogenicity of small doses of inhaled N-nitrosoacetoxymethyl-N-methylamine in Syrian golden hamsters. J Cancer Res Clin Oncol. 1986;111(2):108-9. PMID: 3700456.

" Xn, N Not dangerous goods.

LKT N3276 Nitroso(acetoxymethyl)methylamine 50 mg 421.7 NNK precursor found in tobacco smoke; carcinogen. Acetoxymethyl methylnitrosamine Methyl(acetoxymethyl)nitrosamine; α-Acetoxy dimethylnitrosamine 56856-83-8 ≥98% 132.12 C4H8N2O3 CC(=O)OCN(C)N=O Ambient -20°C Soluble in water. "Proulx LI, Gaudreault M, Turmel V, et al. 4-(Methylnitrosamino)-1-(3-pyridyl)-1-butanone, a component of tobacco smoke, modulates mediator release from human bronchial and alveolar epithelial cells. Clin Exp Immunol. 2005 Apr;140(1):46-53. PMID: 15762874.

Cloutier JF, Drouin R, Castonguay A. Treatment of human cells with N-Nitroso(acetoxymethyl)methylamine: distribution patterns of piperidine-sensitive DNA damage at the nucleotide level of resolution are related to the sequence context. Chem Res Toxicol. 1999 Sep;12(9):840-9. PMID: 10490506.

Klein RG, Schmezer P, Komitowski D. Carcinogenicity of small doses of inhaled N-nitrosoacetoxymethyl-N-methylamine in Syrian golden hamsters. J Cancer Res Clin Oncol. 1986;111(2):108-9. PMID: 3700456.

" Xn, N Not dangerous goods.

LKT N3276 Nitroso(acetoxymethyl)methylamine 100 mg 742.7 NNK precursor found in tobacco smoke; carcinogen. Acetoxymethyl methylnitrosamine Methyl(acetoxymethyl)nitrosamine; α-Acetoxy dimethylnitrosamine 56856-83-8 ≥98% 132.12 C4H8N2O3 CC(=O)OCN(C)N=O Ambient -20°C Soluble in water. "Proulx LI, Gaudreault M, Turmel V, et al. 4-(Methylnitrosamino)-1-(3-pyridyl)-1-butanone, a component of tobacco smoke, modulates mediator release from human bronchial and alveolar epithelial cells. Clin Exp Immunol. 2005 Apr;140(1):46-53. PMID: 15762874.

Cloutier JF, Drouin R, Castonguay A. Treatment of human cells with N-Nitroso(acetoxymethyl)methylamine: distribution patterns of piperidine-sensitive DNA damage at the nucleotide level of resolution are related to the sequence context. Chem Res Toxicol. 1999 Sep;12(9):840-9. PMID: 10490506.

Klein RG, Schmezer P, Komitowski D. Carcinogenicity of small doses of inhaled N-nitrosoacetoxymethyl-N-methylamine in Syrian golden hamsters. J Cancer Res Clin Oncol. 1986;111(2):108-9. PMID: 3700456.

" Xn, N Not dangerous goods.

LKT R1876 all-trans-Retinol 500 mg 192.9 Diterpene component of vitamin A, differentiation inducer; RAR and RXR agonist. 3,7-Dimethyl-9-(2,6,6-trimethyl-1-cyclchexen-1-yl)-2,- 4,6,8-nonatetraen-1-ol Alphasterol; Retinol; Avitol; Vitamin A 68-26-8 ≥95% 286.45 C20H30O CC1=C(C(CCC1)(C)C)C=CC(=CC=CC(=CCO)C)C Blue Ice -20°C Soluble in alcohol, methanol, chloroform, ether, fats or oils. "Friedman MD, Jeevan DS, Tobias M, et al. Targeting cancer stem cells in glioblastoma multiforme using mTOR inhibitors and the differentiating agent all-trans retinoic acid. Oncol Rep. 2013 Oct;30(4):1645-50. PMID: 23877261.

Farhangi MA, Keshavarz SA, Eshraghian M, et al. Vitamin a supplementation and serum Th1- and th2-associated cytokine response in women. J Am Coll Nutr. 2013 Aug;32(4):280-5. PMID: 24024773.

Sharma RB, Wang Q, Khillan JS. Amplification of tumor inducing putative cancer stem cells (CSCs) by vitamin A/retinol from mammary tumors. Biochem Biophys Res Commun. 2013 Jul 12;436(4):625-31. PMID: 23764401.

Zhan XX, Liu Y, Yang JF, et al. All-trans-retinoic acid ameliorates experimental allergic encephalomyelitis by affecting dendritic cell and monocyte development. Immunology. 2013 Apr;138(4):333-45. PMID: 23181351.

Duester G. Retinoic acid synthesis and signaling during early organogenesis. Cell. 2008 Sep 19;134(6):921-31. PMID: 18805086.

" Xn Not dangerous goods.

LKT R1860 Repaglinide 100 mg 121.9 Sulfonylurea; ATP-sensitive K+ channel blocker. 2-ethoxy-4-[2-[[(1S)-3-methyl-1-(2-piperidin-1-ylphenyl)butyl]amino]-2-oxoethyl]benzoic acid 135062-02-1 ≥98% 452.59 C27H36N2O4 CCOC1=C(C=CC(=C1)CC(=O)NC(CC(C)C)C2=CC=CC=C2N3CCCCC3)C(=O)O Ambient Ambient "Zünkler BJ. Human ether-a-go-go-related (HERG) gene and ATP-sensitive potassium channels as targets for adverse drug effects. Pharmacol Ther. 2006 Oct;112(1):12-37. PMID: 16647758.

Proks P, Reimann F, Green N, et al. Sulfonylurea stimulation of insulin secretion. Diabetes. 2002 Dec;51 Suppl 3:S368-76. PMID: 12475777.

Hatorp V. Clinical pharmacokinetics and pharmacodynamics of repaglinide. Clin Pharmacokinet. 2002;41(7):471-83. PMID: 12083976.

" Not dangerous goods.

LKT R1860 Repaglinide 250 mg 234.5 Sulfonylurea; ATP-sensitive K+ channel blocker. 2-ethoxy-4-[2-[[(1S)-3-methyl-1-(2-piperidin-1-ylphenyl)butyl]amino]-2-oxoethyl]benzoic acid 135062-02-1 ≥98% 452.59 C27H36N2O4 CCOC1=C(C=CC(=C1)CC(=O)NC(CC(C)C)C2=CC=CC=C2N3CCCCC3)C(=O)O Ambient Ambient "Zünkler BJ. Human ether-a-go-go-related (HERG) gene and ATP-sensitive potassium channels as targets for adverse drug effects. Pharmacol Ther. 2006 Oct;112(1):12-37. PMID: 16647758.

Proks P, Reimann F, Green N, et al. Sulfonylurea stimulation of insulin secretion. Diabetes. 2002 Dec;51 Suppl 3:S368-76. PMID: 12475777.

Hatorp V. Clinical pharmacokinetics and pharmacodynamics of repaglinide. Clin Pharmacokinet. 2002;41(7):471-83. PMID: 12083976.

" Not dangerous goods.

LKT N3278 7-Nitroindazole 500 mg 104.3 nNOS inhibitor. 7-nitro-1H-Indazole 2942-42-9 ≥98% 163.14 C7H5N3O2 C1=CC2=C(C(=C1)[N+](=O)[O-])NN=C2 Ambient 4°C Soluble in DMSO, ethanol or methanol. Cheng HF, Wang JL, Zhang MZ, et al. Nitric oxide regulates renal cortical cyclooxygenase-2 expression. Am J Physiol Renal Physiol. 2000 Jul;279(1):F122-9. PMID: 10894794. T "UN number: 2811     Class: 6.1     Packing Group: III

Proper shipping name: Toxic solid, organic, n.o.s. (7-Nitroindazole)"

LKT N3278 7-Nitroindazole 1 g 138.9 nNOS inhibitor. 7-nitro-1H-Indazole 2942-42-9 ≥98% 163.14 C7H5N3O2 C1=CC2=C(C(=C1)[N+](=O)[O-])NN=C2 Ambient 4°C Soluble in DMSO, ethanol or methanol. Cheng HF, Wang JL, Zhang MZ, et al. Nitric oxide regulates renal cortical cyclooxygenase-2 expression. Am J Physiol Renal Physiol. 2000 Jul;279(1):F122-9. PMID: 10894794. T "UN number: 2811     Class: 6.1     Packing Group: III

Proper shipping name: Toxic solid, organic, n.o.s. (7-Nitroindazole)"

LKT R1860 Repaglinide 1 g 750.1 Sulfonylurea; ATP-sensitive K+ channel blocker. 2-ethoxy-4-[2-[[(1S)-3-methyl-1-(2-piperidin-1-ylphenyl)butyl]amino]-2-oxoethyl]benzoic acid 135062-02-1 ≥98% 452.59 C27H36N2O4 CCOC1=C(C=CC(=C1)CC(=O)NC(CC(C)C)C2=CC=CC=C2N3CCCCC3)C(=O)O Ambient Ambient "Zünkler BJ. Human ether-a-go-go-related (HERG) gene and ATP-sensitive potassium channels as targets for adverse drug effects. Pharmacol Ther. 2006 Oct;112(1):12-37. PMID: 16647758.

Proks P, Reimann F, Green N, et al. Sulfonylurea stimulation of insulin secretion. Diabetes. 2002 Dec;51 Suppl 3:S368-76. PMID: 12475777.

Hatorp V. Clinical pharmacokinetics and pharmacodynamics of repaglinide. Clin Pharmacokinet. 2002;41(7):471-83. PMID: 12083976.

" Not dangerous goods.

LKT N3278 7-Nitroindazole 5 g 462.1 nNOS inhibitor. 7-nitro-1H-Indazole 2942-42-9 ≥98% 163.14 C7H5N3O2 C1=CC2=C(C(=C1)[N+](=O)[O-])NN=C2 Ambient 4°C Soluble in DMSO, ethanol or methanol. Cheng HF, Wang JL, Zhang MZ, et al. Nitric oxide regulates renal cortical cyclooxygenase-2 expression. Am J Physiol Renal Physiol. 2000 Jul;279(1):F122-9. PMID: 10894794. T "UN number: 2811     Class: 6.1     Packing Group: III

Proper shipping name: Toxic solid, organic, n.o.s. (7-Nitroindazole)"

LKT N3310 Nicotinamide 50 g 70.2 Amide form of vitamin B3 required for production of NAD and NADP; GABA modulator. 3-Pyridinecarboxylic acid amide Niacinamide; Nicotinic acid amide; Pyridine-3-carboxylic acid amide; Vitamin PP; Vitamin B3 98-92-0 ≥98% 122.12 C6H6N2O C1=CC(=CN=C1)C(=O)N Ambient Ambient Soluble in water (>600 mg/mL), ethanol (180 mg/mL), or glycerol. Insoluble in ether or acetone. "Navarrete-Solís J, Castanedo-Cázares JP, Torres-Álvarez B, et al. A Double-Blind, Randomized Clinical Trial of Niacinamide 4% versus Hydroquinone 4% in the Treatment of Melasma. Dermatol Res Pract. 2011;2011:379173. PMID: 21822427.

Niren NM. Pharmacologic doses of nicotinamide in the treatment of inflammatory skin conditions: a review. Cutis. 2006 Jan;77(1 Suppl):11-6. PMID: 16871774.

Akhundov RA, Sultanov AA, Gadzhily RA, et al. Psychoregulating role of nicotinamide. Biull Eksp Biol Med. 1993 May;115(5):487-91. PMID: 7913840.

Paul SM, Marangos PJ, Skolnick P, et al. Biological substrates of anxiety: benzodiazepine receptors and endogenous ligands. Encephale. 1982;8(2):131-44. PMID: 6125374.

" Xi Not dangerous goods.

LKT N3322 Niflumic Acid 10 g 54.4 NSAID; NMDA inverse agonist, T-type Ca2+ and Cl-  channel blocker, GABA-A antagonist, COX-1/2 inhibitor. 2-[[3-Trifluoromethyl)phenyl]amino]-3-pyridine- carboxylic acid "Actol; Forenol; Nifluril

" 4394-00-7 ≥98% 282.22 C13H9F3N2O2 C1=CC(=CC(=C1)NC2=C(C=CC=N2)C(=O)O)C(F)(F)F Hygroscopic. Ambient Ambient Soluble in DMSO, ethanol, methanol or acetonitrile. "Balderas E, Ateaga-Tlecuitl R, Rivera M, et al. Niflumic acid blocks native and recombinant T-type channels. J Cell Physiol. 2012 Jun;227(6):2542-55. PMID: 21898399.

Chi Y, Li K, Yan Q, et al. Nonsteroidal anti-inflammatory drug flufenamic acid is a potent activator of AMP-activated protein kinase. J Pharmacol Exp Ther. 2011 Oct;339(1):257-66. PMID: 21765041.

Sinkkonen ST, Mansikkamäki S, Möykkynen T, et al. Receptor subtype-dependent positive and negative modulation of GABA(A) receptor function by niflumic acid, a nonsteroidal anti-inflammatory drug. Mol Pharmacol. 2003 Sep;64(3):753-63. PMID: 12920213.

Lerma J, Martín del Río R. Chloride transport blockers prevent N-methyl-D-aspartate receptor-channel complex activation. Mol Pharmacol. 1992 Feb;41(2):217-22. PMID: 1371581.

" Xn "UN number: 2811     Class: 6.1     Packing Group: III

Proper shipping name: Toxic solid, organic, n.o.s. (Niflumic acid)"

LKT N3322 Niflumic Acid 25 g 115.5 NSAID; NMDA inverse agonist, T-type Ca2+ and Cl-  channel blocker, GABA-A antagonist, COX-1/2 inhibitor. 2-[[3-Trifluoromethyl)phenyl]amino]-3-pyridine- carboxylic acid "Actol; Forenol; Nifluril

" 4394-00-7 ≥98% 282.22 C13H9F3N2O2 C1=CC(=CC(=C1)NC2=C(C=CC=N2)C(=O)O)C(F)(F)F Hygroscopic. Ambient Ambient Soluble in DMSO, ethanol, methanol or acetonitrile. "Balderas E, Ateaga-Tlecuitl R, Rivera M, et al. Niflumic acid blocks native and recombinant T-type channels. J Cell Physiol. 2012 Jun;227(6):2542-55. PMID: 21898399.

Chi Y, Li K, Yan Q, et al. Nonsteroidal anti-inflammatory drug flufenamic acid is a potent activator of AMP-activated protein kinase. J Pharmacol Exp Ther. 2011 Oct;339(1):257-66. PMID: 21765041.

Sinkkonen ST, Mansikkamäki S, Möykkynen T, et al. Receptor subtype-dependent positive and negative modulation of GABA(A) receptor function by niflumic acid, a nonsteroidal anti-inflammatory drug. Mol Pharmacol. 2003 Sep;64(3):753-63. PMID: 12920213.

Lerma J, Martín del Río R. Chloride transport blockers prevent N-methyl-D-aspartate receptor-channel complex activation. Mol Pharmacol. 1992 Feb;41(2):217-22. PMID: 1371581.

" Xn "UN number: 2811     Class: 6.1     Packing Group: III

Proper shipping name: Toxic solid, organic, n.o.s. (Niflumic acid)"

LKT R1806 Rebamipide 1 g 54.4 Quinolone, antioxidant. α-[(4-Chlorobenzoyl)-amino]-1,2-dihydro-2-oxo-4-quinolinepropanoic acid Proamipide; OPC-12759; Mucosta 90098-04-7 ≥98% 370.79 C19H15ClN2O4 C1=CC=C2C(=C1)C(=CC(=O)N2)CC(C(=O)O)NC(=O)C3=CC=C(C=C3)Cl Ambient Ambient Soluble in dimethyl- formamide, DMSO (74mg/mL). Slightly soluble in water, methanol and ethanol. "Nagano Y, Matsui H, Muramatsu M, et al. Rebamipide significantly inhibits indomethacin-induced mitochondrial damage, lipid peroxidation, and apoptosis in gastric epithelial RGM-1 cells. Dig Dis Sci. 2005 Oct;50 Suppl 1:S76-83. PMID: 16184425.

Arakawa T, Kobayashi K, Yoshikawa T, et al. Rebamipide: overview of its mechanisms of action and efficacy in mucosal protection and ulcer healing. Dig Dis Sci. 1998 Sep;43(9 Suppl):5S-13S. PMID: 9753220.

Arakawa T, Watanabe T, Fukuda T, et al. Rebamipide, novel prostaglandin-inducer accelerates healing and reduces relapse of acetic acid-induced rat gastric ulcer. Comparison with cimetidine. Dig Dis Sci. 1995 Nov;40(11):2469-72. PMID: 7587834.

" None "UN number: 2811     Class: 6.1     Packing group: III

Proper shipping name: Toxic solids, organic, n.o.s. (Rebamipide)

Poison Inhalation Hazard: No"

LKT R1806 Rebamipide 5 g 224.3 Quinolone, antioxidant. α-[(4-Chlorobenzoyl)-amino]-1,2-dihydro-2-oxo-4-quinolinepropanoic acid Proamipide; OPC-12759; Mucosta 90098-04-7 ≥98% 370.79 C19H15ClN2O4 C1=CC=C2C(=C1)C(=CC(=O)N2)CC(C(=O)O)NC(=O)C3=CC=C(C=C3)Cl Ambient Ambient Soluble in dimethyl- formamide, DMSO (74mg/mL). Slightly soluble in water, methanol and ethanol. "Nagano Y, Matsui H, Muramatsu M, et al. Rebamipide significantly inhibits indomethacin-induced mitochondrial damage, lipid peroxidation, and apoptosis in gastric epithelial RGM-1 cells. Dig Dis Sci. 2005 Oct;50 Suppl 1:S76-83. PMID: 16184425.

Arakawa T, Kobayashi K, Yoshikawa T, et al. Rebamipide: overview of its mechanisms of action and efficacy in mucosal protection and ulcer healing. Dig Dis Sci. 1998 Sep;43(9 Suppl):5S-13S. PMID: 9753220.

Arakawa T, Watanabe T, Fukuda T, et al. Rebamipide, novel prostaglandin-inducer accelerates healing and reduces relapse of acetic acid-induced rat gastric ulcer. Comparison with cimetidine. Dig Dis Sci. 1995 Nov;40(11):2469-72. PMID: 7587834.

" None "UN number: 2811     Class: 6.1     Packing group: III

Proper shipping name: Toxic solids, organic, n.o.s. (Rebamipide)

Poison Inhalation Hazard: No"

LKT N3346 Nilotinib 10 mg 121.4 Phenylamino pyridine; Abl, c-Kit, PDGFR, PP2A inhibitor. 4-Methyl-N-(3-(4-methylimidazol-1-yl)-5-(trifluoromethyl)phenyl)-3-((4-pyridin-3-ylpyrimidin-2-yl)amino)benzamide AMN 107, Tasigna 641571-10-0 ≥98% 529.52 C28H22F3N7O CC1=C(C=C(C=C1)C(=O)NC2=CC(=CC(=C2)N3C=C(N=C3)C)C(F)(F)F)NC4=NC=CC(=N4)C5=CN=CC=C5 Ambient Ambient "Shaker ME, Ghani A, Shiha GE, et al. Nilotinib induces apoptosis and autophagic cell death of activated hepatic stellate cells via inhibition of histone deacetylases. Biochim Biophys Acta. 2013 Aug;1833(8):1992-2003. PMID: 23499874.

Yu HC, Lin CS, Tai WT, et al. Nilotinib induces autophagy in hepatocellular carcinoma through AMPK activation. J Biol Chem. 2013 Jun 21;288(25):18249-59. PMID: 23677989.

El-Agamy DS. Anti-allergic effects of nilotinib on mast cell-mediated anaphylaxis like reactions. Eur J Pharmacol. 2012 Apr 5;680(1-3):115-21. PMID: 22329898.

Fabbro D, Manley PW, Jahnke W, et al. Inhibitors of the Abl kinase directed at either the ATP- or myristate-binding site. Biochim Biophys Acta. 2010 Mar;1804(3):454-62. PMID: 20152788.

Quintás-Cardama A, Cortes J. Nilotinib: a phenylamino-pyrimidine derivative with activity against BCR-ABL, KIT and PDGFR kinases. Future Oncol. 2008 Oct;4(5):611-21. PMID: 18922118.

" Not dangerous goods.

LKT N3346 Nilotinib 25 mg 242.7 Phenylamino pyridine; Abl, c-Kit, PDGFR, PP2A inhibitor. 4-Methyl-N-(3-(4-methylimidazol-1-yl)-5-(trifluoromethyl)phenyl)-3-((4-pyridin-3-ylpyrimidin-2-yl)amino)benzamide AMN 107, Tasigna 641571-10-0 ≥98% 529.52 C28H22F3N7O CC1=C(C=C(C=C1)C(=O)NC2=CC(=CC(=C2)N3C=C(N=C3)C)C(F)(F)F)NC4=NC=CC(=N4)C5=CN=CC=C5 Ambient Ambient "Shaker ME, Ghani A, Shiha GE, et al. Nilotinib induces apoptosis and autophagic cell death of activated hepatic stellate cells via inhibition of histone deacetylases. Biochim Biophys Acta. 2013 Aug;1833(8):1992-2003. PMID: 23499874.

Yu HC, Lin CS, Tai WT, et al. Nilotinib induces autophagy in hepatocellular carcinoma through AMPK activation. J Biol Chem. 2013 Jun 21;288(25):18249-59. PMID: 23677989.

El-Agamy DS. Anti-allergic effects of nilotinib on mast cell-mediated anaphylaxis like reactions. Eur J Pharmacol. 2012 Apr 5;680(1-3):115-21. PMID: 22329898.

Fabbro D, Manley PW, Jahnke W, et al. Inhibitors of the Abl kinase directed at either the ATP- or myristate-binding site. Biochim Biophys Acta. 2010 Mar;1804(3):454-62. PMID: 20152788.

Quintás-Cardama A, Cortes J. Nilotinib: a phenylamino-pyrimidine derivative with activity against BCR-ABL, KIT and PDGFR kinases. Future Oncol. 2008 Oct;4(5):611-21. PMID: 18922118.

" Not dangerous goods.

LKT N3346 Nilotinib 100 mg 910 Phenylamino pyridine; Abl, c-Kit, PDGFR, PP2A inhibitor. 4-Methyl-N-(3-(4-methylimidazol-1-yl)-5-(trifluoromethyl)phenyl)-3-((4-pyridin-3-ylpyrimidin-2-yl)amino)benzamide AMN 107, Tasigna 641571-10-0 ≥98% 529.52 C28H22F3N7O CC1=C(C=C(C=C1)C(=O)NC2=CC(=CC(=C2)N3C=C(N=C3)C)C(F)(F)F)NC4=NC=CC(=N4)C5=CN=CC=C5 Ambient Ambient "Shaker ME, Ghani A, Shiha GE, et al. Nilotinib induces apoptosis and autophagic cell death of activated hepatic stellate cells via inhibition of histone deacetylases. Biochim Biophys Acta. 2013 Aug;1833(8):1992-2003. PMID: 23499874.

Yu HC, Lin CS, Tai WT, et al. Nilotinib induces autophagy in hepatocellular carcinoma through AMPK activation. J Biol Chem. 2013 Jun 21;288(25):18249-59. PMID: 23677989.

El-Agamy DS. Anti-allergic effects of nilotinib on mast cell-mediated anaphylaxis like reactions. Eur J Pharmacol. 2012 Apr 5;680(1-3):115-21. PMID: 22329898.

Fabbro D, Manley PW, Jahnke W, et al. Inhibitors of the Abl kinase directed at either the ATP- or myristate-binding site. Biochim Biophys Acta. 2010 Mar;1804(3):454-62. PMID: 20152788.

Quintás-Cardama A, Cortes J. Nilotinib: a phenylamino-pyrimidine derivative with activity against BCR-ABL, KIT and PDGFR kinases. Future Oncol. 2008 Oct;4(5):611-21. PMID: 18922118.

" Not dangerous goods.

LKT R1806 Rebamipide 25 g 611.5 Quinolone, antioxidant. α-[(4-Chlorobenzoyl)-amino]-1,2-dihydro-2-oxo-4-quinolinepropanoic acid Proamipide; OPC-12759; Mucosta 90098-04-7 ≥98% 370.79 C19H15ClN2O4 C1=CC=C2C(=C1)C(=CC(=O)N2)CC(C(=O)O)NC(=O)C3=CC=C(C=C3)Cl Ambient Ambient Soluble in dimethyl- formamide, DMSO (74mg/mL). Slightly soluble in water, methanol and ethanol. "Nagano Y, Matsui H, Muramatsu M, et al. Rebamipide significantly inhibits indomethacin-induced mitochondrial damage, lipid peroxidation, and apoptosis in gastric epithelial RGM-1 cells. Dig Dis Sci. 2005 Oct;50 Suppl 1:S76-83. PMID: 16184425.

Arakawa T, Kobayashi K, Yoshikawa T, et al. Rebamipide: overview of its mechanisms of action and efficacy in mucosal protection and ulcer healing. Dig Dis Sci. 1998 Sep;43(9 Suppl):5S-13S. PMID: 9753220.

Arakawa T, Watanabe T, Fukuda T, et al. Rebamipide, novel prostaglandin-inducer accelerates healing and reduces relapse of acetic acid-induced rat gastric ulcer. Comparison with cimetidine. Dig Dis Sci. 1995 Nov;40(11):2469-72. PMID: 7587834.

" None "UN number: 2811     Class: 6.1     Packing group: III

Proper shipping name: Toxic solids, organic, n.o.s. (Rebamipide)

Poison Inhalation Hazard: No"

LKT R1780 trans-Retinoic Acid 500 mg 61.1 Vitamin A carboxylic acid; RAR agonist. (all-E)-3,7-Dimethyl-9-(2,6,6-trimethyl- 1-cyclo-hexen- 1-yl)-2,4,6,8-nonatetraenoic acid Retinoic acid; Vitamin A acid; tretinoin; Aberel; Avita; Eudyna; Kerlocal; Renova; Retin-A; Vesanoid 302-79-4 ≥98% 300.44 C20H28O2 CC1=C(C(CCC1)(C)C)C=CC(=CC=CC(=CC(=O)O)C)C Ambient -20°C Soluble in DMSO. Slightly soluble in polyethylene glycol, octanol or ethanol. Practically insoluble in water, mineral oil or glycerin. "Chen S, Yang Y, Xu J, et al. Effect of all-trans-retinoic acid on enterovirus 71 infection in vitro. Br J Nutr. 2014 May;111(9):1586-93. PMID: 24495389.

Zhang ML, Tao Y, Zhou WQ, et al. All-trans retinoic acid induces cell-cycle arrest in human cutaneous squamous carcinoma cells by inhibiting the mitogen-activated protein kinase-activated protein 1 pathway. Clin Exp Dermatol. 2014 Apr;39(3):354-60. PMID: 24635079.

Busch AM, Galimberti F, Nehls KE, et al. All-trans-retinoic acid antagonizes the Hedgehog pathway by inducing patched. Cancer Biol Ther. 2014 Apr;15(4):463-72. PMID: 24496080.

Zhang C, Kong X, Ning G, et al. All-trans retinoic acid prevents epidural fibrosis through NF-κB signaling pathway in post-laminectomy rats. Neuropharmacology. 2014 Apr;79:275-81. PMID: 24316159.

Wheelwright M, Kim EW, Inkeles MS, et al. All-trans retinoic acid-triggered antimicrobial activity against Mycobacterium tuberculosis is dependent on NPC2. J Immunol. 2014 Mar 1;192(5):2280-90. PMID: 24501203.

Zhu YF, Hu JZ, Zhao PN, et al. All-transretinoic acid regulates Th1/Th2 balance in CD4+ T cells when GATA-3 is deficient. Biomed Environ Sci. 2013 Sep;26(9):774-7. PMID: 24099613.

Chomienne C, Ballerini P, Balitrand N, et al. All-trans retinoic acid in acute promyelocytic leukemias. II. In vitro studies: structure-function relationship. Blood. 1990 Nov 1;76(9):1710-7. PMID: 2224120.

" Repr., Xn, Xi Not dangerous goods.

LKT R1780 trans-Retinoic Acid 1 g 101.9 Vitamin A carboxylic acid; RAR agonist. (all-E)-3,7-Dimethyl-9-(2,6,6-trimethyl- 1-cyclo-hexen- 1-yl)-2,4,6,8-nonatetraenoic acid Retinoic acid; Vitamin A acid; tretinoin; Aberel; Avita; Eudyna; Kerlocal; Renova; Retin-A; Vesanoid 302-79-4 ≥98% 300.44 C20H28O2 CC1=C(C(CCC1)(C)C)C=CC(=CC=CC(=CC(=O)O)C)C Ambient -20°C Soluble in DMSO. Slightly soluble in polyethylene glycol, octanol or ethanol. Practically insoluble in water, mineral oil or glycerin. "Chen S, Yang Y, Xu J, et al. Effect of all-trans-retinoic acid on enterovirus 71 infection in vitro. Br J Nutr. 2014 May;111(9):1586-93. PMID: 24495389.

Zhang ML, Tao Y, Zhou WQ, et al. All-trans retinoic acid induces cell-cycle arrest in human cutaneous squamous carcinoma cells by inhibiting the mitogen-activated protein kinase-activated protein 1 pathway. Clin Exp Dermatol. 2014 Apr;39(3):354-60. PMID: 24635079.

Busch AM, Galimberti F, Nehls KE, et al. All-trans-retinoic acid antagonizes the Hedgehog pathway by inducing patched. Cancer Biol Ther. 2014 Apr;15(4):463-72. PMID: 24496080.

Zhang C, Kong X, Ning G, et al. All-trans retinoic acid prevents epidural fibrosis through NF-κB signaling pathway in post-laminectomy rats. Neuropharmacology. 2014 Apr;79:275-81. PMID: 24316159.

Wheelwright M, Kim EW, Inkeles MS, et al. All-trans retinoic acid-triggered antimicrobial activity against Mycobacterium tuberculosis is dependent on NPC2. J Immunol. 2014 Mar 1;192(5):2280-90. PMID: 24501203.

Zhu YF, Hu JZ, Zhao PN, et al. All-transretinoic acid regulates Th1/Th2 balance in CD4+ T cells when GATA-3 is deficient. Biomed Environ Sci. 2013 Sep;26(9):774-7. PMID: 24099613.

Chomienne C, Ballerini P, Balitrand N, et al. All-trans retinoic acid in acute promyelocytic leukemias. II. In vitro studies: structure-function relationship. Blood. 1990 Nov 1;76(9):1710-7. PMID: 2224120.

" Repr., Xn, Xi Not dangerous goods.

LKT R1780 trans-Retinoic Acid 5 g 305.9 Vitamin A carboxylic acid; RAR agonist. (all-E)-3,7-Dimethyl-9-(2,6,6-trimethyl- 1-cyclo-hexen- 1-yl)-2,4,6,8-nonatetraenoic acid Retinoic acid; Vitamin A acid; tretinoin; Aberel; Avita; Eudyna; Kerlocal; Renova; Retin-A; Vesanoid 302-79-4 ≥98% 300.44 C20H28O2 CC1=C(C(CCC1)(C)C)C=CC(=CC=CC(=CC(=O)O)C)C Ambient -20°C Soluble in DMSO. Slightly soluble in polyethylene glycol, octanol or ethanol. Practically insoluble in water, mineral oil or glycerin. "Chen S, Yang Y, Xu J, et al. Effect of all-trans-retinoic acid on enterovirus 71 infection in vitro. Br J Nutr. 2014 May;111(9):1586-93. PMID: 24495389.

Zhang ML, Tao Y, Zhou WQ, et al. All-trans retinoic acid induces cell-cycle arrest in human cutaneous squamous carcinoma cells by inhibiting the mitogen-activated protein kinase-activated protein 1 pathway. Clin Exp Dermatol. 2014 Apr;39(3):354-60. PMID: 24635079.

Busch AM, Galimberti F, Nehls KE, et al. All-trans-retinoic acid antagonizes the Hedgehog pathway by inducing patched. Cancer Biol Ther. 2014 Apr;15(4):463-72. PMID: 24496080.

Zhang C, Kong X, Ning G, et al. All-trans retinoic acid prevents epidural fibrosis through NF-κB signaling pathway in post-laminectomy rats. Neuropharmacology. 2014 Apr;79:275-81. PMID: 24316159.

Wheelwright M, Kim EW, Inkeles MS, et al. All-trans retinoic acid-triggered antimicrobial activity against Mycobacterium tuberculosis is dependent on NPC2. J Immunol. 2014 Mar 1;192(5):2280-90. PMID: 24501203.

Zhu YF, Hu JZ, Zhao PN, et al. All-transretinoic acid regulates Th1/Th2 balance in CD4+ T cells when GATA-3 is deficient. Biomed Environ Sci. 2013 Sep;26(9):774-7. PMID: 24099613.

Chomienne C, Ballerini P, Balitrand N, et al. All-trans retinoic acid in acute promyelocytic leukemias. II. In vitro studies: structure-function relationship. Blood. 1990 Nov 1;76(9):1710-7. PMID: 2224120.

" Repr., Xn, Xi Not dangerous goods.

LKT N3422 Nifekalant Hydrochloride 10 mg 136 Voltage-gated K+ channel blocker. 6-[2-[(N-2-Hydroxyethyl)-3-(4-nitrophenyl)-propyl- amino(ethylamino)-1,3-dimethyl-1H,3H - pyrimidine- 2,4-dione monohydrochloride MS 551 130656-51-8 ≥98% 441.91 C19H27N5O5 HCl CN1C(=CC(=O)N(C1=O)C)NCCN(CCCC2=CC=C(C=C2)[N+](=O)[O-])CCO.Cl Ambient Ambient "Harayama N, Nihei SI, Nagata K, et al. Comparison of nifekalant and amiodarone for resuscitation of out-of-hospital cardiopulmonary arrest resulting from shock-resistant ventricular fibrillation. J Anesth. 2014 Jan 5. [Epub ahead of print]. PMID: 24389941.

Sonoda K, Watanabe I, Ohkubo K, et al. Rate-dependent electrophysiologic effects of the class III antiarrhythmic drugs nifekalant, amiodarone, and ibutilide on the atrium in patients with persistent atrial fibrillation. Int Heart J. 2013;54(5):279-84. PMID: 24097216.

Pantazopoulos IN, Troupis GT, Pantazopoulos CN, et al. Nifekalant in the treatment of life-threatening ventricular tachyarrhythmias. World J Cardiol. 2011 Jun 26;3(6):169-76. PMID: 21772943.

" Not dangerous goods.

LKT N3422 Nifekalant Hydrochloride 25 mg 269.1 Voltage-gated K+ channel blocker. 6-[2-[(N-2-Hydroxyethyl)-3-(4-nitrophenyl)-propyl- amino(ethylamino)-1,3-dimethyl-1H,3H - pyrimidine- 2,4-dione monohydrochloride MS 551 130656-51-8 ≥98% 441.91 C19H27N5O5 HCl CN1C(=CC(=O)N(C1=O)C)NCCN(CCCC2=CC=C(C=C2)[N+](=O)[O-])CCO.Cl Ambient Ambient "Harayama N, Nihei SI, Nagata K, et al. Comparison of nifekalant and amiodarone for resuscitation of out-of-hospital cardiopulmonary arrest resulting from shock-resistant ventricular fibrillation. J Anesth. 2014 Jan 5. [Epub ahead of print]. PMID: 24389941.

Sonoda K, Watanabe I, Ohkubo K, et al. Rate-dependent electrophysiologic effects of the class III antiarrhythmic drugs nifekalant, amiodarone, and ibutilide on the atrium in patients with persistent atrial fibrillation. Int Heart J. 2013;54(5):279-84. PMID: 24097216.

Pantazopoulos IN, Troupis GT, Pantazopoulos CN, et al. Nifekalant in the treatment of life-threatening ventricular tachyarrhythmias. World J Cardiol. 2011 Jun 26;3(6):169-76. PMID: 21772943.

" Not dangerous goods.

LKT N3448 Nimodipine 500 mg 92.5 L-type Ca2+ channel blocker. 1,4-Dihydro-2,6-dimethyl-4-(3-nitrophenyl)-3,5- pyridinedicarboxylic acid 2-methoxyethyl 1-methyl- ethyl ester Periplum; Nimotop 66085-59-4 ≥98% 418.44 C21H26N2O7 CC1=C(C(C(=C(N1)C)C(=O)OC(C)C)C2=CC(=CC=C2)[N+](=O)[O-])C(=O)OCCOC Ambient ambient Soluble in methanol or DMSO. Insoluble in water. "Bia A GY, Polak P, Michalak A, et al. Influence of calcium channel antagonists on nonsomatic signs of nicotine and d-amphetamine withdrawal in mice. Pharmacol Rep. 2014 Apr;66(2):212-22. PMID: 24911072.

Bailey JM, Hutsell BA, Newland MC. Dietary nimodipine delays the onset of methylmercury neurotoxicity in mice. Neurotoxicology. 2013 Jul;37:108-17. PMID: 23583802.

Sanz JM, Chiozzi P, Colaianna M, et al. Nimodipine inhibits IL-1β release stimulated by amyloid β from microglia. Br J Pharmacol. 2012 Dec;167(8):1702-11. PMID: 22831460.

Sharma N, Cho DH, Kim SY, et al. Magnesium sulfate suppresses L-type calcium currents on the basilar artery smooth muscle cells in rabbits. Neurol Res. 2012 Apr;34(3):291-6. PMID: 22450340.

Janjua N, Mayer SA. Cerebral vasospasm after subarachnoid hemorrhage. Curr Opin Crit Care. 2003 Apr;9(2):113-9. PMID: 12657973.

" Xn Not dangerous goods.

LKT "R1779

" 13-cis-Retinoic Acid 100 mg 81.6 Vitamin A metabolite, differentiation inducer; RAR and RXR agonist. "3,7-Dimethyl-9-(2,6,6-trimethyl-1-cyclohexen-1-yl)2-cis-4-

trans-6-trans-8-trans-nonatetraenoic acid" Isotretinoin; Isotrex; 13-cis-Vitamin A acid; Teriosal 4759-48-2 ≥98% 300.44 C20H28O2 CC1=C(C(CCC1)(C)C)C=CC(=CC=CC(=CC(=O)O)C)C Ambient -20°C Sparingly soluble in water. "Shah N, Wang J, Selich-Anderson J, et al. PBX1 is a favorable prognostic biomarker as it modulates 13-cis retinoic acid-mediated differentiation in neuroblastoma. Clin Cancer Res. 2014 Aug 15;20(16):4400-12. PMID: 24947929.

Frey-Wagner I, Fischbeck A, Cee A, et al. Effects of retinoids in mouse models of colitis: benefit or danger to the gastrointestinal tract? Inflamm Bowel Dis. 2013 Oct;19(11):2356-65. PMID: 23899542.

Snyder R, Thekkumkara T. 13-cis-Retinoic acid specific down-regulation of angiotensin type 1 receptor in rat liver epithelial and aortic smooth muscle cells. J Mol Endocrinol. 2012 Feb 6;48(2):99-114. PMID: 22180636.

" T Not dangerous goods.

LKT N3448 Nimodipine 1 g 161.9 L-type Ca2+ channel blocker. 1,4-Dihydro-2,6-dimethyl-4-(3-nitrophenyl)-3,5- pyridinedicarboxylic acid 2-methoxyethyl 1-methyl- ethyl ester Periplum; Nimotop 66085-59-4 ≥98% 418.44 C21H26N2O7 CC1=C(C(C(=C(N1)C)C(=O)OC(C)C)C2=CC(=CC=C2)[N+](=O)[O-])C(=O)OCCOC Ambient ambient Soluble in methanol or DMSO. Insoluble in water. "Bia A GY, Polak P, Michalak A, et al. Influence of calcium channel antagonists on nonsomatic signs of nicotine and d-amphetamine withdrawal in mice. Pharmacol Rep. 2014 Apr;66(2):212-22. PMID: 24911072.

Bailey JM, Hutsell BA, Newland MC. Dietary nimodipine delays the onset of methylmercury neurotoxicity in mice. Neurotoxicology. 2013 Jul;37:108-17. PMID: 23583802.

Sanz JM, Chiozzi P, Colaianna M, et al. Nimodipine inhibits IL-1β release stimulated by amyloid β from microglia. Br J Pharmacol. 2012 Dec;167(8):1702-11. PMID: 22831460.

Sharma N, Cho DH, Kim SY, et al. Magnesium sulfate suppresses L-type calcium currents on the basilar artery smooth muscle cells in rabbits. Neurol Res. 2012 Apr;34(3):291-6. PMID: 22450340.

Janjua N, Mayer SA. Cerebral vasospasm after subarachnoid hemorrhage. Curr Opin Crit Care. 2003 Apr;9(2):113-9. PMID: 12657973.

" Xn Not dangerous goods.

LKT N3448 Nimodipine 5 g 577.6 L-type Ca2+ channel blocker. 1,4-Dihydro-2,6-dimethyl-4-(3-nitrophenyl)-3,5- pyridinedicarboxylic acid 2-methoxyethyl 1-methyl- ethyl ester Periplum; Nimotop 66085-59-4 ≥98% 418.44 C21H26N2O7 CC1=C(C(C(=C(N1)C)C(=O)OC(C)C)C2=CC(=CC=C2)[N+](=O)[O-])C(=O)OCCOC Ambient ambient Soluble in methanol or DMSO. Insoluble in water. "Bia A GY, Polak P, Michalak A, et al. Influence of calcium channel antagonists on nonsomatic signs of nicotine and d-amphetamine withdrawal in mice. Pharmacol Rep. 2014 Apr;66(2):212-22. PMID: 24911072.

Bailey JM, Hutsell BA, Newland MC. Dietary nimodipine delays the onset of methylmercury neurotoxicity in mice. Neurotoxicology. 2013 Jul;37:108-17. PMID: 23583802.

Sanz JM, Chiozzi P, Colaianna M, et al. Nimodipine inhibits IL-1β release stimulated by amyloid β from microglia. Br J Pharmacol. 2012 Dec;167(8):1702-11. PMID: 22831460.

Sharma N, Cho DH, Kim SY, et al. Magnesium sulfate suppresses L-type calcium currents on the basilar artery smooth muscle cells in rabbits. Neurol Res. 2012 Apr;34(3):291-6. PMID: 22450340.

Janjua N, Mayer SA. Cerebral vasospasm after subarachnoid hemorrhage. Curr Opin Crit Care. 2003 Apr;9(2):113-9. PMID: 12657973.

" Xn Not dangerous goods.

LKT "R1779

" 13-cis-Retinoic Acid 250 mg 163.2 Vitamin A metabolite, differentiation inducer; RAR and RXR agonist. "3,7-Dimethyl-9-(2,6,6-trimethyl-1-cyclohexen-1-yl)2-cis-4-

trans-6-trans-8-trans-nonatetraenoic acid" Isotretinoin; Isotrex; 13-cis-Vitamin A acid; Teriosal 4759-48-2 ≥98% 300.44 C20H28O2 CC1=C(C(CCC1)(C)C)C=CC(=CC=CC(=CC(=O)O)C)C Ambient -20°C Sparingly soluble in water. "Shah N, Wang J, Selich-Anderson J, et al. PBX1 is a favorable prognostic biomarker as it modulates 13-cis retinoic acid-mediated differentiation in neuroblastoma. Clin Cancer Res. 2014 Aug 15;20(16):4400-12. PMID: 24947929.

Frey-Wagner I, Fischbeck A, Cee A, et al. Effects of retinoids in mouse models of colitis: benefit or danger to the gastrointestinal tract? Inflamm Bowel Dis. 2013 Oct;19(11):2356-65. PMID: 23899542.

Snyder R, Thekkumkara T. 13-cis-Retinoic acid specific down-regulation of angiotensin type 1 receptor in rat liver epithelial and aortic smooth muscle cells. J Mol Endocrinol. 2012 Feb 6;48(2):99-114. PMID: 22180636.

" T Not dangerous goods.

LKT "R1779

" 13-cis-Retinoic Acid 500 mg 271.7 Vitamin A metabolite, differentiation inducer; RAR and RXR agonist. "3,7-Dimethyl-9-(2,6,6-trimethyl-1-cyclohexen-1-yl)2-cis-4-

trans-6-trans-8-trans-nonatetraenoic acid" Isotretinoin; Isotrex; 13-cis-Vitamin A acid; Teriosal 4759-48-2 ≥98% 300.44 C20H28O2 CC1=C(C(CCC1)(C)C)C=CC(=CC=CC(=CC(=O)O)C)C Ambient -20°C Sparingly soluble in water. "Shah N, Wang J, Selich-Anderson J, et al. PBX1 is a favorable prognostic biomarker as it modulates 13-cis retinoic acid-mediated differentiation in neuroblastoma. Clin Cancer Res. 2014 Aug 15;20(16):4400-12. PMID: 24947929.

Frey-Wagner I, Fischbeck A, Cee A, et al. Effects of retinoids in mouse models of colitis: benefit or danger to the gastrointestinal tract? Inflamm Bowel Dis. 2013 Oct;19(11):2356-65. PMID: 23899542.

Snyder R, Thekkumkara T. 13-cis-Retinoic acid specific down-regulation of angiotensin type 1 receptor in rat liver epithelial and aortic smooth muscle cells. J Mol Endocrinol. 2012 Feb 6;48(2):99-114. PMID: 22180636.

" T Not dangerous goods.

LKT R1777 9-cis-Retinoic Acid 1 mg 45 Vitamin A derivative; RAR and RXR agonist. (2E,4E,6Z,8E)-3,7-Dimethyl-9-(2,6,6-trimethylcyclohex-1-enyl) nona-2,4,6,8-tetraenoic Acid 9-cis-Tretinoin; Panrexin, Alitretinoin 5300-03-8 ≥98% 300.44 C20H28O2 CC1=C(C(CCC1)(C)C)C=CC(=CC=CC(=CC(=O)O)C)C Blue Ice -80°C Soluble in DMSO and ethanol. "Shan PR, Xu WW, Huang ZQ, et al. Protective role of retinoid X receptor in H9c2 cardiomyocytes from hypoxia/reoxygenation injury in rats. World J Emerg Med. 2014;5(2):122-7. PMID: 25215161.

Reiner DJ, Yu SJ, Shen H, et al. 9-Cis retinoic acid protects against methamphetamine-induced neurotoxicity in nigrostriatal dopamine neurons. Neurotox Res. 2014 Apr;25(3):248-61. PMID: 23884514.

Szabó DR, Baghy K, Szabó PM, et al. Antitumoral effects of 9-cis retinoic acid in adrenocortical cancer. Cell Mol Life Sci. 2014 Mar;71(5):917-32. PMID: 23807211.

Sagara C, Takahashi K, Kagechika H, et al. Molecular mechanism of 9-cis-retinoic acid inhibition of adipogenesis in 3T3-L1 cells. Biochem Biophys Res Commun. 2013 Mar 29;433(1):102-7. PMID: 23485459.

Yin LH, Shen H, Diaz-Ruiz O, et al. Early post-treatment with 9-cis retinoic acid reduces neurodegeneration of dopaminergic neurons in a rat model of Parkinson's disease. BMC Neurosci. 2012 Oct 6;13:120. PMID: 23040108.

Choi I, Lee S, Kyoung Chung H, et al. 9-cis retinoic acid promotes lymphangiogenesis and enhances lymphatic vessel regeneration: therapeutic implications of 9-cis retinoic acid for secondary lymphedema. Circulation. 2012 Feb 21;125(7):872-82. PMID: 22275501.

Kolseth IB, Agren J, Sundvold-Gjerstad V, et al. 9-cis retinoic acid inhibits inflammatory responses of adherent monocytes and increases their ability to induce classical monocyte migration. J Innate Immun. 2012;4(2):176-86. PMID: 22213773." Xi, Repr. Not dangerous goods.

LKT R1777 9-cis-Retinoic Acid 5 mg 85 Vitamin A derivative; RAR and RXR agonist. (2E,4E,6Z,8E)-3,7-Dimethyl-9-(2,6,6-trimethylcyclohex-1-enyl) nona-2,4,6,8-tetraenoic Acid 9-cis-Tretinoin; Panrexin, Alitretinoin 5300-03-8 ≥98% 300.44 C20H28O2 CC1=C(C(CCC1)(C)C)C=CC(=CC=CC(=CC(=O)O)C)C Blue Ice -80°C Soluble in DMSO and ethanol. "Shan PR, Xu WW, Huang ZQ, et al. Protective role of retinoid X receptor in H9c2 cardiomyocytes from hypoxia/reoxygenation injury in rats. World J Emerg Med. 2014;5(2):122-7. PMID: 25215161.

Reiner DJ, Yu SJ, Shen H, et al. 9-Cis retinoic acid protects against methamphetamine-induced neurotoxicity in nigrostriatal dopamine neurons. Neurotox Res. 2014 Apr;25(3):248-61. PMID: 23884514.

Szabó DR, Baghy K, Szabó PM, et al. Antitumoral effects of 9-cis retinoic acid in adrenocortical cancer. Cell Mol Life Sci. 2014 Mar;71(5):917-32. PMID: 23807211.

Sagara C, Takahashi K, Kagechika H, et al. Molecular mechanism of 9-cis-retinoic acid inhibition of adipogenesis in 3T3-L1 cells. Biochem Biophys Res Commun. 2013 Mar 29;433(1):102-7. PMID: 23485459.

Yin LH, Shen H, Diaz-Ruiz O, et al. Early post-treatment with 9-cis retinoic acid reduces neurodegeneration of dopaminergic neurons in a rat model of Parkinson's disease. BMC Neurosci. 2012 Oct 6;13:120. PMID: 23040108.

Choi I, Lee S, Kyoung Chung H, et al. 9-cis retinoic acid promotes lymphangiogenesis and enhances lymphatic vessel regeneration: therapeutic implications of 9-cis retinoic acid for secondary lymphedema. Circulation. 2012 Feb 21;125(7):872-82. PMID: 22275501.

Kolseth IB, Agren J, Sundvold-Gjerstad V, et al. 9-cis retinoic acid inhibits inflammatory responses of adherent monocytes and increases their ability to induce classical monocyte migration. J Innate Immun. 2012;4(2):176-86. PMID: 22213773." Xi, Repr. Not dangerous goods.

LKT R1777 9-cis-Retinoic Acid 25 mg 350 Vitamin A derivative; RAR and RXR agonist. (2E,4E,6Z,8E)-3,7-Dimethyl-9-(2,6,6-trimethylcyclohex-1-enyl) nona-2,4,6,8-tetraenoic Acid 9-cis-Tretinoin; Panrexin, Alitretinoin 5300-03-8 ≥98% 300.44 C20H28O2 CC1=C(C(CCC1)(C)C)C=CC(=CC=CC(=CC(=O)O)C)C Blue Ice -80°C Soluble in DMSO and ethanol. "Shan PR, Xu WW, Huang ZQ, et al. Protective role of retinoid X receptor in H9c2 cardiomyocytes from hypoxia/reoxygenation injury in rats. World J Emerg Med. 2014;5(2):122-7. PMID: 25215161.

Reiner DJ, Yu SJ, Shen H, et al. 9-Cis retinoic acid protects against methamphetamine-induced neurotoxicity in nigrostriatal dopamine neurons. Neurotox Res. 2014 Apr;25(3):248-61. PMID: 23884514.

Szabó DR, Baghy K, Szabó PM, et al. Antitumoral effects of 9-cis retinoic acid in adrenocortical cancer. Cell Mol Life Sci. 2014 Mar;71(5):917-32. PMID: 23807211.

Sagara C, Takahashi K, Kagechika H, et al. Molecular mechanism of 9-cis-retinoic acid inhibition of adipogenesis in 3T3-L1 cells. Biochem Biophys Res Commun. 2013 Mar 29;433(1):102-7. PMID: 23485459.

Yin LH, Shen H, Diaz-Ruiz O, et al. Early post-treatment with 9-cis retinoic acid reduces neurodegeneration of dopaminergic neurons in a rat model of Parkinson's disease. BMC Neurosci. 2012 Oct 6;13:120. PMID: 23040108.

Choi I, Lee S, Kyoung Chung H, et al. 9-cis retinoic acid promotes lymphangiogenesis and enhances lymphatic vessel regeneration: therapeutic implications of 9-cis retinoic acid for secondary lymphedema. Circulation. 2012 Feb 21;125(7):872-82. PMID: 22275501.

Kolseth IB, Agren J, Sundvold-Gjerstad V, et al. 9-cis retinoic acid inhibits inflammatory responses of adherent monocytes and increases their ability to induce classical monocyte migration. J Innate Immun. 2012;4(2):176-86. PMID: 22213773." Xi, Repr. Not dangerous goods.

LKT N3450 Nimesulide 5 g 72.2 NSAID; COX-2 inhibitor. N-(4-Nitro-2-phenoxyphenyl)methanesulfonamide Aulin; Fansidol; Flogovital; Mesulid; Nide; Nidol; Nisulid 51803-78-2 ≥98% 308.31 C13H12N2O5S CS(=O)(=O)NC1=C(C=C(C=C1)[N+](=O)[O-])OC2=CC=CC=C2 Ambient Ambient Soluble in chloroform. "Jia-Jun T, Su-Mei L, Liang Y, et al. Nimesulide inhibited the growth of hypopharyngeal carcinoma cells via suppressing Survivin expression. Head Neck Oncol. 2012 Mar 27;4:7. PMID: 22453101.

Vellani V, Franchi S, Prandini M, et al. Nimesulide inhibits protein kinase C epsilon and substance P in sensory neurons - comparison with paracetamol. J Pain Res. 2011;4:177-87. PMID: 21811393.

Suleyman H, Cadirci E, Albayrak A, et al. Nimesulide is a selective COX-2 inhibitory, atypical non-steroidal anti-inflammatory drug. Curr Med Chem. 2008;15(3):278-83. PMID: 18333314.

" Xn "UN number: 2811     Class: 6.1     Packing Group: III

Proper shipping name: Toxic solid, organic, n.o.s. (Nimesulide)"

LKT N3450 Nimesulide 10 g 130 NSAID; COX-2 inhibitor. N-(4-Nitro-2-phenoxyphenyl)methanesulfonamide Aulin; Fansidol; Flogovital; Mesulid; Nide; Nidol; Nisulid 51803-78-2 ≥98% 308.31 C13H12N2O5S CS(=O)(=O)NC1=C(C=C(C=C1)[N+](=O)[O-])OC2=CC=CC=C2 Ambient Ambient Soluble in chloroform. "Jia-Jun T, Su-Mei L, Liang Y, et al. Nimesulide inhibited the growth of hypopharyngeal carcinoma cells via suppressing Survivin expression. Head Neck Oncol. 2012 Mar 27;4:7. PMID: 22453101.

Vellani V, Franchi S, Prandini M, et al. Nimesulide inhibits protein kinase C epsilon and substance P in sensory neurons - comparison with paracetamol. J Pain Res. 2011;4:177-87. PMID: 21811393.

Suleyman H, Cadirci E, Albayrak A, et al. Nimesulide is a selective COX-2 inhibitory, atypical non-steroidal anti-inflammatory drug. Curr Med Chem. 2008;15(3):278-83. PMID: 18333314.

" Xn "UN number: 2811     Class: 6.1     Packing Group: III

Proper shipping name: Toxic solid, organic, n.o.s. (Nimesulide)"

LKT N3450 Nimesulide 25 g 259.6 NSAID; COX-2 inhibitor. N-(4-Nitro-2-phenoxyphenyl)methanesulfonamide Aulin; Fansidol; Flogovital; Mesulid; Nide; Nidol; Nisulid 51803-78-2 ≥98% 308.31 C13H12N2O5S CS(=O)(=O)NC1=C(C=C(C=C1)[N+](=O)[O-])OC2=CC=CC=C2 Ambient Ambient Soluble in chloroform. "Jia-Jun T, Su-Mei L, Liang Y, et al. Nimesulide inhibited the growth of hypopharyngeal carcinoma cells via suppressing Survivin expression. Head Neck Oncol. 2012 Mar 27;4:7. PMID: 22453101.

Vellani V, Franchi S, Prandini M, et al. Nimesulide inhibits protein kinase C epsilon and substance P in sensory neurons - comparison with paracetamol. J Pain Res. 2011;4:177-87. PMID: 21811393.

Suleyman H, Cadirci E, Albayrak A, et al. Nimesulide is a selective COX-2 inhibitory, atypical non-steroidal anti-inflammatory drug. Curr Med Chem. 2008;15(3):278-83. PMID: 18333314.

" Xn "UN number: 2811     Class: 6.1     Packing Group: III

Proper shipping name: Toxic solid, organic, n.o.s. (Nimesulide)"

LKT N3452 Nimustine Hydrochloride 100 mg 40.7 Nitrosourea, DNA cross-linker. N'-[(4-Amino-2-methyl-5-pyrimidinyl)methyl]-N-(2- chloroethyl)-N-nitrosourea hydrochloride "ACNU; Nidran

" 55661-38-6 ≥97% 309.16 C9H13ClN6O2 CC1=NC=C(C(=N1)N)CNC(=O)N(CCCl)N=O.Cl Decomposes slowly in humid air. Ambient 4°C Soluble in methanol and n-butanol. Soluble in water (100 mM) and DMSO (75 mM).  (Practically insoluble in ethyl acetate, ether, chloroform and benzene. "Kondo N, Takahashi A, Mori E, et al. DNA ligase IV is a potential molecular target in ACNU sensitivity. Cancer Sci. 2010 Aug;101(8):1881-5. PMID: 20487264.

Kanamaru R, Asamura M, Sato H, et al. Studies on the mechanism of action of ACNU, 1-(4-amino-2-methylpyrimidine-5-yl) methyl-3-(2-chloroethyl)-3-nitrosourea hydrochloride: effects on cultured HeLa S3 cells. Tohoku J Exp Med. 1980 Dec;132(4):431-41. PMID: 6942530.

" T "UN number: 2811   Class:  6.1   Packing group:  III

Proper shipping name:  Toxic solids, organic, n.o.s. (Nimustine hydrochloride)

Marine pollutant:  No

Poison Inhalation Hazard:  No"

LKT N3452 Nimustine Hydrochloride 500 mg 67.9 Nitrosourea, DNA cross-linker. N'-[(4-Amino-2-methyl-5-pyrimidinyl)methyl]-N-(2- chloroethyl)-N-nitrosourea hydrochloride "ACNU; Nidran

" 55661-38-6 ≥97% 309.16 C9H13ClN6O2 CC1=NC=C(C(=N1)N)CNC(=O)N(CCCl)N=O.Cl Decomposes slowly in humid air. Ambient 4°C Soluble in methanol and n-butanol. Soluble in water (100 mM) and DMSO (75 mM).  (Practically insoluble in ethyl acetate, ether, chloroform and benzene. "Kondo N, Takahashi A, Mori E, et al. DNA ligase IV is a potential molecular target in ACNU sensitivity. Cancer Sci. 2010 Aug;101(8):1881-5. PMID: 20487264.

Kanamaru R, Asamura M, Sato H, et al. Studies on the mechanism of action of ACNU, 1-(4-amino-2-methylpyrimidine-5-yl) methyl-3-(2-chloroethyl)-3-nitrosourea hydrochloride: effects on cultured HeLa S3 cells. Tohoku J Exp Med. 1980 Dec;132(4):431-41. PMID: 6942530.

" T "UN number: 2811   Class:  6.1   Packing group:  III

Proper shipping name:  Toxic solids, organic, n.o.s. (Nimustine hydrochloride)

Marine pollutant:  No

Poison Inhalation Hazard:  No"

LKT N3452 Nimustine Hydrochloride 1 g 92.5 Nitrosourea, DNA cross-linker. N'-[(4-Amino-2-methyl-5-pyrimidinyl)methyl]-N-(2- chloroethyl)-N-nitrosourea hydrochloride "ACNU; Nidran

" 55661-38-6 ≥97% 309.16 C9H13ClN6O2 CC1=NC=C(C(=N1)N)CNC(=O)N(CCCl)N=O.Cl Decomposes slowly in humid air. Ambient 4°C Soluble in methanol and n-butanol. Soluble in water (100 mM) and DMSO (75 mM).  (Practically insoluble in ethyl acetate, ether, chloroform and benzene. "Kondo N, Takahashi A, Mori E, et al. DNA ligase IV is a potential molecular target in ACNU sensitivity. Cancer Sci. 2010 Aug;101(8):1881-5. PMID: 20487264.

Kanamaru R, Asamura M, Sato H, et al. Studies on the mechanism of action of ACNU, 1-(4-amino-2-methylpyrimidine-5-yl) methyl-3-(2-chloroethyl)-3-nitrosourea hydrochloride: effects on cultured HeLa S3 cells. Tohoku J Exp Med. 1980 Dec;132(4):431-41. PMID: 6942530.

" T "UN number: 2811   Class:  6.1   Packing group:  III

Proper shipping name:  Toxic solids, organic, n.o.s. (Nimustine hydrochloride)

Marine pollutant:  No

Poison Inhalation Hazard:  No"

LKT R1776 Resveratrol 100 mg 61.1 Phenolic phytoalexin found in soy, grapes, and peanuts. SIRT1 activator, MAO inhibitor. 1,3-Benzenediol, 5-(2-(4-hydroxyphenyl)ethenyl)-, (E)- 3,4',5-Stilbenetrio; 3,4',5-Trihydroxystilbene 501-36-0 ≥98% 228.24 C14H12O3 C1=CC(=CC=C1C=CC2=CC(=CC(=C2)O)O)O Ambient -20°C Soluble in DMSO and ethanol. "Mohar DS, Malik S. The Sirtuin System: The Holy Grail of Resveratrol? J Clin Exp Cardiolog. 2012 Nov;3(11). 216. PMID: 23560248.

Vingtdeux V, Giliberto L, Zhao H, et al. AMP-activated protein kinase signaling activation by resveratrol modulates amyloid-beta peptide metabolism. J Biol Chem. 2010 Mar 19;285(12):9100-13. PMID: 20080969.

Karuppagounder SS, Pinto JT, Xu H, et al. Dietary supplementation with resveratrol reduces plaque pathology in a transgenic model of Alzheimer's disease. Neurochem Int. 2009 Feb;54(2):111-8. PMID: 19041676.

Athar M, Back JH, Tang X, et al. Resveratrol: a review of preclinical studies for human cancer prevention. Toxicol Appl Pharmacol. 2007 Nov 1;224(3):274-83. PMID: 17306316.

Yáñez M, Fraiz N, Cano E, et al. Inhibitory effects of cis- and trans-resveratrol on noradrenaline and 5-hydroxytryptamine uptake and on monoamine oxidase activity. Biochem Biophys Res Commun. 2006 Jun 2;344(2):688-95. PMID: 16631124.

Marambaud P, Zhao H, Davies P. Resveratrol promotes clearance of Alzheimer's disease amyloid-beta peptides. J Biol Chem. 2005 Nov 11;280(45):37377-82. PMID: 16162502.

Narayanan N, Nargi D, Randolph C, et al. Liposome encapsulation of curcumin and resveratrol in combination reduces prostate cancer incidence in PTEN knockout mice. Int J Cancer. 2009 Feb 6;125(1):1-8. PMID: 19326431.

Huang A, Yang YM, Yan C, et al. Altered MAPK signaling in progressive deterioration of endothelial function in diabetic mice. Diabetes. 2012 Dec;61(12):3181-3188. PMID: 22933112.

Back JH, Rezvani HR, Zhu Y, et al. Cancer cell survival following DNA damage-mediated premature senescence is regulated by mammalian target of rapamycin (mTOR)-dependent inhibition of sirtuin 1. J Biol Chem. 2011 May 27;286(21):19100-19108. PMID: 21471201.

" Xi Not dangerous goods.

LKT R1776 Resveratrol 500 mg 242.7 Phenolic phytoalexin found in soy, grapes, and peanuts. SIRT1 activator, MAO inhibitor. 1,3-Benzenediol, 5-(2-(4-hydroxyphenyl)ethenyl)-, (E)- 3,4',5-Stilbenetrio; 3,4',5-Trihydroxystilbene 501-36-0 ≥98% 228.24 C14H12O3 C1=CC(=CC=C1C=CC2=CC(=CC(=C2)O)O)O Ambient -20°C Soluble in DMSO and ethanol. "Mohar DS, Malik S. The Sirtuin System: The Holy Grail of Resveratrol? J Clin Exp Cardiolog. 2012 Nov;3(11). 216. PMID: 23560248.

Vingtdeux V, Giliberto L, Zhao H, et al. AMP-activated protein kinase signaling activation by resveratrol modulates amyloid-beta peptide metabolism. J Biol Chem. 2010 Mar 19;285(12):9100-13. PMID: 20080969.

Karuppagounder SS, Pinto JT, Xu H, et al. Dietary supplementation with resveratrol reduces plaque pathology in a transgenic model of Alzheimer's disease. Neurochem Int. 2009 Feb;54(2):111-8. PMID: 19041676.

Athar M, Back JH, Tang X, et al. Resveratrol: a review of preclinical studies for human cancer prevention. Toxicol Appl Pharmacol. 2007 Nov 1;224(3):274-83. PMID: 17306316.

Yáñez M, Fraiz N, Cano E, et al. Inhibitory effects of cis- and trans-resveratrol on noradrenaline and 5-hydroxytryptamine uptake and on monoamine oxidase activity. Biochem Biophys Res Commun. 2006 Jun 2;344(2):688-95. PMID: 16631124.

Marambaud P, Zhao H, Davies P. Resveratrol promotes clearance of Alzheimer's disease amyloid-beta peptides. J Biol Chem. 2005 Nov 11;280(45):37377-82. PMID: 16162502.

Narayanan N, Nargi D, Randolph C, et al. Liposome encapsulation of curcumin and resveratrol in combination reduces prostate cancer incidence in PTEN knockout mice. Int J Cancer. 2009 Feb 6;125(1):1-8. PMID: 19326431.

Huang A, Yang YM, Yan C, et al. Altered MAPK signaling in progressive deterioration of endothelial function in diabetic mice. Diabetes. 2012 Dec;61(12):3181-3188. PMID: 22933112.

Back JH, Rezvani HR, Zhu Y, et al. Cancer cell survival following DNA damage-mediated premature senescence is regulated by mammalian target of rapamycin (mTOR)-dependent inhibition of sirtuin 1. J Biol Chem. 2011 May 27;286(21):19100-19108. PMID: 21471201.

" Xi Not dangerous goods.

LKT N3496 Nizatidine 5 g 47.6 Histamine H2 inverse agonist. "N-(2-(((2-((Dimethylamino)methyl)-4-

thiazolyl)methyl)thio)ethyl)-N'-methyl-2-nitro- 1,1-ethenediamine

" Calmaxid; Cronizat; Distaxid; Gastrax; Naxidine; Nizax; Nizaxid; Tazac; Zanizal. 76963-41-2 ≥98% 331.46 C12H21N5O2S2 CNC(=C[N+](=O)[O-])NCCSCC1=CSC(=N1)CN(C)C Ambient Ambient Soluble in chloroform (>100mg/mL), methanol (50-100mg/mL), or water (10-33mg/mL). "Doi H, Sakakibara R, Sato M, et al. Nizatidine ameliorates gastroparesis in Parkinson's disease: a pilot study. Mov Disord. 2014 Apr;29(4):562-6. PMID: 24375669.

Wang S, Wu B, Xue J, et al. Nizatidine, a small molecular compound, enhances killed H5N1 vaccine cell-mediated responses and protects mice from lethal viral challenge. Hum Vaccin Immunother. 2014 Feb 1;10(2):461-8. PMID: 24253609.

Kurt A, Altun A, Bağcivan I, et al. Effects of proton pump inhibitors and h(2) receptor antagonists on the ileum motility. Gastroenterol Res Pract. 2011;2011:218342. PMID: 22216022.

" Xn Not dangerous goods.

LKT N3496 Nizatidine 10 g 81.6 Histamine H2 inverse agonist. "N-(2-(((2-((Dimethylamino)methyl)-4-

thiazolyl)methyl)thio)ethyl)-N'-methyl-2-nitro- 1,1-ethenediamine

" Calmaxid; Cronizat; Distaxid; Gastrax; Naxidine; Nizax; Nizaxid; Tazac; Zanizal. 76963-41-2 ≥98% 331.46 C12H21N5O2S2 CNC(=C[N+](=O)[O-])NCCSCC1=CSC(=N1)CN(C)C Ambient Ambient Soluble in chloroform (>100mg/mL), methanol (50-100mg/mL), or water (10-33mg/mL). "Doi H, Sakakibara R, Sato M, et al. Nizatidine ameliorates gastroparesis in Parkinson's disease: a pilot study. Mov Disord. 2014 Apr;29(4):562-6. PMID: 24375669.

Wang S, Wu B, Xue J, et al. Nizatidine, a small molecular compound, enhances killed H5N1 vaccine cell-mediated responses and protects mice from lethal viral challenge. Hum Vaccin Immunother. 2014 Feb 1;10(2):461-8. PMID: 24253609.

Kurt A, Altun A, Bağcivan I, et al. Effects of proton pump inhibitors and h(2) receptor antagonists on the ileum motility. Gastroenterol Res Pract. 2011;2011:218342. PMID: 22216022.

" Xn Not dangerous goods.

LKT N3520 Nifursol 25 g 61.1 Nitrofuran, livestock antibiotic. 3,5-Dinitrosalicylic acid (5-nitrofurfurylidene)hydrazide Histomon; Salfuride; Sulfuride 16915-70-1 ≥98% 365.21 C12H7N5O9 C1=C(OC(=C1)[N+](=O)[O-])C=NNC(=O)C2=CC(=CC(=C2O)[N+](=O)[O-])[N+](=O)[O-] Ambient Ambient "Verdon E, Couedor P, Sanders P. Multi-residue monitoring for the simultaneous determination of five nitrofurans (furazolidone, furaltadone, nitrofurazone, nitrofurantoine, nifursol) in poultry muscle tissue through the detection of their five major metabolites (AOZ, AMOZ, SEM, AHD, DNSAH) by liquid chromatography coupled to electrospray tandem mass spectrometry--in-house validation in line with Commission Decision 657/2002/EC. Anal Chim Acta. 2007 Mar 14;586(1-2):336-47. PMID: 17386733.

Callait MP, Granier C, Chauve C, et al. In vitro activity of therapeutic drugs against Histomonas meleagridis (Smith, 1895). Poult Sci. 2002 Aug;81(8):1122-7. PMID: 12211302.

" Not dangerous goods.

LKT N3520 Nifursol 100 g 149.5 Nitrofuran, livestock antibiotic. 3,5-Dinitrosalicylic acid (5-nitrofurfurylidene)hydrazide Histomon; Salfuride; Sulfuride 16915-70-1 ≥98% 365.21 C12H7N5O9 C1=C(OC(=C1)[N+](=O)[O-])C=NNC(=O)C2=CC(=CC(=C2O)[N+](=O)[O-])[N+](=O)[O-] Ambient Ambient "Verdon E, Couedor P, Sanders P. Multi-residue monitoring for the simultaneous determination of five nitrofurans (furazolidone, furaltadone, nitrofurazone, nitrofurantoine, nifursol) in poultry muscle tissue through the detection of their five major metabolites (AOZ, AMOZ, SEM, AHD, DNSAH) by liquid chromatography coupled to electrospray tandem mass spectrometry--in-house validation in line with Commission Decision 657/2002/EC. Anal Chim Acta. 2007 Mar 14;586(1-2):336-47. PMID: 17386733.

Callait MP, Granier C, Chauve C, et al. In vitro activity of therapeutic drugs against Histomonas meleagridis (Smith, 1895). Poult Sci. 2002 Aug;81(8):1122-7. PMID: 12211302.

" Not dangerous goods.

LKT N5210 Nociceptin 1 mg 302.4 Endogenous neuropeptide, involved in opioid signaling; NOP agonist. Orphanin FQ 170713-75-4 ≥98% 1809.1 C79H129N27O22 CC(C)CC(C(=O)NC(C)C(=O)NC(CC(=O)N)C(=O)NC(CCC(=O)N)C(=O)O)NC(=O)C(CCCCN)NC(=O)C(CCCNC(=N)N)NC(=O)C(C)NC(=O)C(CO)NC(=O)C(CCCCN)NC(=O)C(CCCNC(=N)N)NC(=O)C(C)NC(=O)CNC(=O)C(C(C)O)NC(=O)C(CC1=CC=CC=C1)NC(=O)CNC(=O)CNC(=O)C(CC2=CC=CC=C2)N Ambient -20°C Soluble in water. "Borgquist A, Rivas VM, Kachani M, et al. Gonadal Steroids Differentially Modulate the Actions of Orphanin FQ/Nociceptin at A Physiologically Relevant Circuit Controlling Female Sexual Receptivity. J Neuroendocrinol. 2014 May;26(5):329-40. PMID: 24617903.

Kallupi M, Varodayan FP, Oleata CS, et al. Nociceptin/orphanin FQ decreases glutamate transmission and blocks ethanol-induced effects in the central amygdala of naive and ethanol-dependent rats. Neuropsychopharmacology. 2014 Apr;39(5):1081-92. PMID: 24169802.

Okuda-Ashitaka E, Minami T, Tachibana S, et al. Nocistatin, a peptide that blocks nociceptin action in pain transmission. Nature. 1998 Mar 19;392(6673):286-9. PMID: 9521323.

" Not dangerous goods.

LKT N5211 Nocistatin 0.5 mg 359.9 Neuropeptide; TRPC agonist, BK/SK K+ channel modulator. ≥95% 772.86 C32H56N10O12 Ambient -20°C "Deák BH, Klukovits A, Tekes K, et al. Nocistatin inhibits pregnant rat uterine contractions in vitro: roles of calcitonin gene-related peptide and calcium-dependent potassium channel. Eur J Pharmacol. 2013 Aug 15;714(1-3):96-104. PMID: 23792038.

Chen YL, Li AH, Yeh TH, et al. Nocistatin and nociceptin exert opposite effects on the excitability of central amygdala nucleus-periaqueductal gray projection neurons. Mol Cell Neurosci. 2009 Jan;40(1):76-88. PMID: 18930828.

Fantin M, Fischetti C, Trapella C, et al. Nocistatin inhibits 5-hydroxytryptamine release in the mouse neocortex via presynaptic Gi/o protein linked pathways. Br J Pharmacol. 2007 Oct;152(4):549-55. PMID: 17618307.

Liu EH, Lee TL, Nishiuchi Y, et al. Nocistatin and its derivatives antagonize the impairment of short-term acquisition induced by nociceptin. Neurosci Lett. 2007 Apr 12;416(2):155-9. PMID: 17306455.

Liu EH, Nishiuchi Y, Kimura T, et al. Supraspinal nocistatin and its amide derivative antagonize the hyperalgesic effects of nociceptin in mice. Neurosci Lett. 2006 Apr 10-17;397(1-2):59-63. PMID: 16384642.

Gavioli EC, Rae GA, Calo' G, et al. Central injections of nocistatin or its C-terminal hexapeptide exert anxiogenic-like effect on behaviour of mice in the plus-maze test. Br J Pharmacol. 2002 Jul;136(5):764-72. PMID: 12086986.

"

LKT N5211 Nocistatin 1 mg 612.4 Neuropeptide; TRPC agonist, BK/SK K+ channel modulator. ≥95% 772.86 C32H56N10O12 Ambient -20°C "Deák BH, Klukovits A, Tekes K, et al. Nocistatin inhibits pregnant rat uterine contractions in vitro: roles of calcitonin gene-related peptide and calcium-dependent potassium channel. Eur J Pharmacol. 2013 Aug 15;714(1-3):96-104. PMID: 23792038.

Chen YL, Li AH, Yeh TH, et al. Nocistatin and nociceptin exert opposite effects on the excitability of central amygdala nucleus-periaqueductal gray projection neurons. Mol Cell Neurosci. 2009 Jan;40(1):76-88. PMID: 18930828.

Fantin M, Fischetti C, Trapella C, et al. Nocistatin inhibits 5-hydroxytryptamine release in the mouse neocortex via presynaptic Gi/o protein linked pathways. Br J Pharmacol. 2007 Oct;152(4):549-55. PMID: 17618307.

Liu EH, Lee TL, Nishiuchi Y, et al. Nocistatin and its derivatives antagonize the impairment of short-term acquisition induced by nociceptin. Neurosci Lett. 2007 Apr 12;416(2):155-9. PMID: 17306455.

Liu EH, Nishiuchi Y, Kimura T, et al. Supraspinal nocistatin and its amide derivative antagonize the hyperalgesic effects of nociceptin in mice. Neurosci Lett. 2006 Apr 10-17;397(1-2):59-63. PMID: 16384642.

Gavioli EC, Rae GA, Calo' G, et al. Central injections of nocistatin or its C-terminal hexapeptide exert anxiogenic-like effect on behaviour of mice in the plus-maze test. Br J Pharmacol. 2002 Jul;136(5):764-72. PMID: 12086986.

"

LKT R1775 Resiniferonol-9,13,14-orthophenyl Acetate 1 mg 134.9 Diterpene vanilloid derivative of resiniferatoxin; potential PKC activator. "Daphnetoxin, 6,7-deepoxy-6,7-didehydro-5-deoxy- 21-dephenyl-21-(phenylmethyl)- 

" "ROPA; ROP

" 57852-42-3 ≥98% 464.56 C28H32O6 CC1CC2(C3C4C1(C5C=C(C(=O)C5(CC(=C4)CO)O)C)OC(O3)(O2)CC6=CC=CC=C6)C(=C)C Ambient -20°C Soluble in DMSO or ethanol. "Frey MR, Clark JA, Bateman NW, et al. Cell cycle- and protein kinase C-specific effects of resiniferatoxin and resiniferonol 9,13,14-ortho-phenylacetate in intestinal epithelial cells. Biochem Pharmacol. 2004 May 15;67(10):1873-86. PMID: 15130764.

Geiges D, Meyer T, Marte B, et al. Activation of protein kinase C subtypes alpha, gamma, delta, epsilon, zeta, and eta by tumor-promoting and nontumor-promoting agents. Biochem Pharmacol. 1997 Mar 21;53(6):865-75. PMID: 9113106.

" Xi Not dangerous goods.

LKT N5211 Nocistatin 2.5 mg 1080.1 Neuropeptide; TRPC agonist, BK/SK K+ channel modulator. ≥95% 772.86 C32H56N10O12 Ambient -20°C "Deák BH, Klukovits A, Tekes K, et al. Nocistatin inhibits pregnant rat uterine contractions in vitro: roles of calcitonin gene-related peptide and calcium-dependent potassium channel. Eur J Pharmacol. 2013 Aug 15;714(1-3):96-104. PMID: 23792038.

Chen YL, Li AH, Yeh TH, et al. Nocistatin and nociceptin exert opposite effects on the excitability of central amygdala nucleus-periaqueductal gray projection neurons. Mol Cell Neurosci. 2009 Jan;40(1):76-88. PMID: 18930828.

Fantin M, Fischetti C, Trapella C, et al. Nocistatin inhibits 5-hydroxytryptamine release in the mouse neocortex via presynaptic Gi/o protein linked pathways. Br J Pharmacol. 2007 Oct;152(4):549-55. PMID: 17618307.

Liu EH, Lee TL, Nishiuchi Y, et al. Nocistatin and its derivatives antagonize the impairment of short-term acquisition induced by nociceptin. Neurosci Lett. 2007 Apr 12;416(2):155-9. PMID: 17306455.

Liu EH, Nishiuchi Y, Kimura T, et al. Supraspinal nocistatin and its amide derivative antagonize the hyperalgesic effects of nociceptin in mice. Neurosci Lett. 2006 Apr 10-17;397(1-2):59-63. PMID: 16384642.

Gavioli EC, Rae GA, Calo' G, et al. Central injections of nocistatin or its C-terminal hexapeptide exert anxiogenic-like effect on behaviour of mice in the plus-maze test. Br J Pharmacol. 2002 Jul;136(5):764-72. PMID: 12086986.

"

LKT R1775 Resiniferonol-9,13,14-orthophenyl Acetate 5 mg 541 Diterpene vanilloid derivative of resiniferatoxin; potential PKC activator. "Daphnetoxin, 6,7-deepoxy-6,7-didehydro-5-deoxy- 21-dephenyl-21-(phenylmethyl)- 

" "ROPA; ROP

" 57852-42-3 ≥98% 464.56 C28H32O6 CC1CC2(C3C4C1(C5C=C(C(=O)C5(CC(=C4)CO)O)C)OC(O3)(O2)CC6=CC=CC=C6)C(=C)C Ambient -20°C Soluble in DMSO or ethanol. "Frey MR, Clark JA, Bateman NW, et al. Cell cycle- and protein kinase C-specific effects of resiniferatoxin and resiniferonol 9,13,14-ortho-phenylacetate in intestinal epithelial cells. Biochem Pharmacol. 2004 May 15;67(10):1873-86. PMID: 15130764.

Geiges D, Meyer T, Marte B, et al. Activation of protein kinase C subtypes alpha, gamma, delta, epsilon, zeta, and eta by tumor-promoting and nontumor-promoting agents. Biochem Pharmacol. 1997 Mar 21;53(6):865-75. PMID: 9113106.

" Xi Not dangerous goods.

LKT R1775 Resiniferonol-9,13,14-orthophenyl Acetate 10 mg 1045.4 Diterpene vanilloid derivative of resiniferatoxin; potential PKC activator. "Daphnetoxin, 6,7-deepoxy-6,7-didehydro-5-deoxy- 21-dephenyl-21-(phenylmethyl)- 

" "ROPA; ROP

" 57852-42-3 ≥98% 464.56 C28H32O6 CC1CC2(C3C4C1(C5C=C(C(=O)C5(CC(=C4)CO)O)C)OC(O3)(O2)CC6=CC=CC=C6)C(=C)C Ambient -20°C Soluble in DMSO or ethanol. "Frey MR, Clark JA, Bateman NW, et al. Cell cycle- and protein kinase C-specific effects of resiniferatoxin and resiniferonol 9,13,14-ortho-phenylacetate in intestinal epithelial cells. Biochem Pharmacol. 2004 May 15;67(10):1873-86. PMID: 15130764.

Geiges D, Meyer T, Marte B, et al. Activation of protein kinase C subtypes alpha, gamma, delta, epsilon, zeta, and eta by tumor-promoting and nontumor-promoting agents. Biochem Pharmacol. 1997 Mar 21;53(6):865-75. PMID: 9113106.

" Xi Not dangerous goods.

LKT N5409 Nocodazole 10 mg 67.9 Microtubule polymerization inhibitor. [5-(2-Thienylcarbonyl)-1H-benzimidazol-2-yl]- carbamic acid methyl ester Oncodazole; R 17934 31430-18-9 ≥98% 301.32 C14H11N3O3S COC(=O)NC1=NC2=C(N1)C=C(C=C2)C(=O)C3=CC=CS3 Blue Ice -20°C Soluble in DMSO. Insoluble in water. "Shkoliar NA, Kukhaleva IV, Legon'kov IuA, et al. Study of the therapeutic activity of nocodazole on experimental models of larval alveococcosis. Med Parazitol (Mosk). 2013 Apr-Jun;(2):20-7. PMID: 24003517.

Beswick RW, Ambrose HE, Wagner SD. Nocodazole, a microtubule de-polymerising agent, induces apoptosis of chronic lymphocytic leukaemia cells associated with changes in Bcl-2 phosphorylation and expression. Leuk Res. 2006 Apr;30(4):427-36. PMID: 16162358.

Rahajeng J, Giridharan SS, Naslavsky N, Caplan S. Collapsin response mediator protein-2 (Crmp2) regulates trafficking by linking endocytic regulatory proteins to dynein motors. J Biol Chem. 2010 Oct 15;285(42):31918-31922. PMID: 20801876.

" Xi, Carc., Repr. Not dangerous goods.

LKT N5409 Nocodazole 50 mg 237.8 Microtubule polymerization inhibitor. [5-(2-Thienylcarbonyl)-1H-benzimidazol-2-yl]- carbamic acid methyl ester Oncodazole; R 17934 31430-18-9 ≥98% 301.32 C14H11N3O3S COC(=O)NC1=NC2=C(N1)C=C(C=C2)C(=O)C3=CC=CS3 Blue Ice -20°C Soluble in DMSO. Insoluble in water. "Shkoliar NA, Kukhaleva IV, Legon'kov IuA, et al. Study of the therapeutic activity of nocodazole on experimental models of larval alveococcosis. Med Parazitol (Mosk). 2013 Apr-Jun;(2):20-7. PMID: 24003517.

Beswick RW, Ambrose HE, Wagner SD. Nocodazole, a microtubule de-polymerising agent, induces apoptosis of chronic lymphocytic leukaemia cells associated with changes in Bcl-2 phosphorylation and expression. Leuk Res. 2006 Apr;30(4):427-36. PMID: 16162358.

Rahajeng J, Giridharan SS, Naslavsky N, Caplan S. Collapsin response mediator protein-2 (Crmp2) regulates trafficking by linking endocytic regulatory proteins to dynein motors. J Biol Chem. 2010 Oct 15;285(42):31918-31922. PMID: 20801876.

" Xi, Carc., Repr. Not dangerous goods.

LKT N5550 Nomilin 25 mg 139.5 Triterpene found in species of Citrus; HIV-1 protease and aromatase inhibitor. 1-(3-Furyl)decaydro-11-hydroxy-4b,7,7-11a,13a- pentamethyloxireno(4,4a)-2-benzopyrano[6,5-g]- (2)benzoxepin-3,5,9(3aH,4bH,6H)-trione acetate 1-(Acetyloxy)-1,2-dihydroobacunoic acid ε-lactone 1063-77-0 ≥98% 514.56 C28H34O9 CC(=O)OC1CC(=O)OC(C2C1(C3CCC4(C(OC(=O)C5C4(C3(C(=O)C2)C)O5)C6=COC=C6)C)C)(C)C Ambient Ambient Soluble in acetone. "Sato R. Nomilin as an anti-obesity and anti-hyperglycemic agent. Vitam Horm. 2013;91:425-39. PMID: 23374727.

Kim J, Jayaprakasha GK, Patil BS. Limonoids and their anti-proliferative and anti-aromatase properties in human breast cancer cells. Food Funct. 2013 Feb;4(2):258-65. PMID: 23117440.

Pratheeshkumar P, Kuttan G. Nomilin inhibits tumor-specific angiogenesis by downregulating VEGF, NO and proinflammatory cytokine profile and also by inhibiting the activation of MMP-2 and MMP-9. Eur J Pharmacol. 2011 Oct 15;668(3):450-8. PMID: 21839074.

Ono E, Inoue J, Hashidume T, et al. Anti-obesity and anti-hyperglycemic effects of the dietary citrus limonoid nomilin in mice fed a high-fat diet. Biochem Biophys Res Commun. 2011 Jul 8;410(3):677-81. PMID: 21693102.

Perez JL, Jayaprakasha GK, Cadena A, et al. In vivo induction of phase II detoxifying enzymes, glutathione transferase and quinone reductase by citrus triterpenoids. BMC Complement Altern Med. 2010 Sep 17;10:51. PMID: 20846448.

Battinelli L, Mengoni F, Lichtner M, et al. Effect of limonin and nomilin on HIV-1 replication on infected human mononuclear cells. Planta Med. 2003 Oct;69(10):910-3. PMID: 14648393.

Raphael TJ, Kuttan G. Effect of naturally occurring triterpenoids glycyrrhizic acid, ursolic acid, oleanolic acid and nomilin on the immune system. Phytomedicine. 2003;10(6-7):483-9. PMID: 13678231.

" Not dangerous goods.

LKT R1752 Renin Inhibitor Peptide 5 mg 144 Peptide; potential vasodilator. ≥95% 1024.24 C52H73N13O9 Ambient -20°C Allan DR, Hui KY, Coletti C, et al. Renin vs. angiotensin-converting enzyme inhibition in the rat: consequences for plasma and renal tissue angiotensin. J Pharmacol Exp Ther. 1997 Nov;283(2):661-5. PMID: 9353383.

LKT R1752 Renin Inhibitor Peptide 10 mg 243.1 Peptide; potential vasodilator. ≥95% 1024.24 C52H73N13O9 Ambient -20°C Allan DR, Hui KY, Coletti C, et al. Renin vs. angiotensin-converting enzyme inhibition in the rat: consequences for plasma and renal tissue angiotensin. J Pharmacol Exp Ther. 1997 Nov;283(2):661-5. PMID: 9353383.

LKT R1752 Renin Inhibitor Peptide 25 mg 432 Peptide; potential vasodilator. ≥95% 1024.24 C52H73N13O9 Ambient -20°C Allan DR, Hui KY, Coletti C, et al. Renin vs. angiotensin-converting enzyme inhibition in the rat: consequences for plasma and renal tissue angiotensin. J Pharmacol Exp Ther. 1997 Nov;283(2):661-5. PMID: 9353383.

LKT R0349 Ramosetron 10 mg 121.9 5-HT3 antagonist. 132036-88-5 ≥98% 279.34 C17H17N3O CN1C=C(C2=CC=CC=C21)C(=O)C3CCC4=C(C3)NC=N4 Ambient Ambient "Kim WJ, Kang H, Shin HY, et al. Ramosetron, midazolam, and combination of ramosetron and midazolam for prevention of postoperative nausea and vomiting: a prospective, randomized, double-blind study. J Int Med Res. 2013 Aug;41(4):1203-13. PMID: 23766412.

Park YM, Lee YJ, Lee YH, et al. Effects of ramosetron on gastrointestinal transit of Guinea pig. J Neurogastroenterol Motil. 2013 Jan;19(1):36-41. Erratum in: J Neurogastroenterol Motil. 2013;19(2):275.  PMID: 23350045.

Yasuda M, Kato S, Yamanaka N, et al. 5-HT3 receptor antagonists ameliorate 5-fluorouracil-induced intestinal mucositis by suppression of apoptosis in murine intestinal crypt cells. Br J Pharmacol. 2013 Mar;168(6):1388-400. PMID: 23072534.

" Not dangerous goods.

LKT R0349 Ramosetron 25 mg 281.2 5-HT3 antagonist. 132036-88-5 ≥98% 279.34 C17H17N3O CN1C=C(C2=CC=CC=C21)C(=O)C3CCC4=C(C3)NC=N4 Ambient Ambient "Kim WJ, Kang H, Shin HY, et al. Ramosetron, midazolam, and combination of ramosetron and midazolam for prevention of postoperative nausea and vomiting: a prospective, randomized, double-blind study. J Int Med Res. 2013 Aug;41(4):1203-13. PMID: 23766412.

Park YM, Lee YJ, Lee YH, et al. Effects of ramosetron on gastrointestinal transit of Guinea pig. J Neurogastroenterol Motil. 2013 Jan;19(1):36-41. Erratum in: J Neurogastroenterol Motil. 2013;19(2):275.  PMID: 23350045.

Yasuda M, Kato S, Yamanaka N, et al. 5-HT3 receptor antagonists ameliorate 5-fluorouracil-induced intestinal mucositis by suppression of apoptosis in murine intestinal crypt cells. Br J Pharmacol. 2013 Mar;168(6):1388-400. PMID: 23072534.

" Not dangerous goods.

LKT R0349 Ramosetron 100 mg 843.9 5-HT3 antagonist. 132036-88-5 ≥98% 279.34 C17H17N3O CN1C=C(C2=CC=CC=C21)C(=O)C3CCC4=C(C3)NC=N4 Ambient Ambient "Kim WJ, Kang H, Shin HY, et al. Ramosetron, midazolam, and combination of ramosetron and midazolam for prevention of postoperative nausea and vomiting: a prospective, randomized, double-blind study. J Int Med Res. 2013 Aug;41(4):1203-13. PMID: 23766412.

Park YM, Lee YJ, Lee YH, et al. Effects of ramosetron on gastrointestinal transit of Guinea pig. J Neurogastroenterol Motil. 2013 Jan;19(1):36-41. Erratum in: J Neurogastroenterol Motil. 2013;19(2):275.  PMID: 23350045.

Yasuda M, Kato S, Yamanaka N, et al. 5-HT3 receptor antagonists ameliorate 5-fluorouracil-induced intestinal mucositis by suppression of apoptosis in murine intestinal crypt cells. Br J Pharmacol. 2013 Mar;168(6):1388-400. PMID: 23072534.

" Not dangerous goods.

LKT R0272 Rasagiline Mesylate 25 mg 75.3 MAO-A/B inhibitor. (R)-N-2-Propynyl-1-indanamine mesylate 161735-79-1 ≥98% 267.34 C12H13NCH3SO3H C#CCNC1CCC2=CC=CC=C12 Ambient Ambient 20.6° Freely soluble in water, methanol and ethanol. "Naoi M, Maruyama W, Inaba-Hasegawa K. Revelation in the neuroprotective functions of rasagiline and selegiline: the induction of distinct genes by different mechanisms. Expert Rev Neurother. 2013 Jun;13(6):671-84. PMID: 23739004.

Naoi M, Maruyama W, Yi H. Rasagiline prevents apoptosis induced by PK11195, a ligand of the outer membrane translocator protein (18 kDa), in SH-SY5Y cells through suppression of cytochrome c release from mitochondria. J Neural Transm. 2013 Nov;120(11):1539-51. PMID: 23681678.

Inaba-Hasegawa K, Akao Y, Maruyama W, et al. Type A monoamine oxidase is associated with induction of neuroprotective Bcl-2 by rasagiline, an inhibitor of type B monoamine oxidase. J Neural Transm. 2012 Apr;119(4):405-14. PMID: 22065207.

Weinreb O, Amit T, Bar-Am O, et al. Induction of neurotrophic factors GDNF and BDNF associated with the mechanism of neurorescue action of rasagiline and ladostigil: new insights and implications for therapy. Ann N Y Acad Sci. 2007 Dec;1122:155-68. PMID: 18077571.

" Not dangerous goods.

LKT R0272 Rasagiline Mesylate 100 mg 209.3 MAO-A/B inhibitor. (R)-N-2-Propynyl-1-indanamine mesylate 161735-79-1 ≥98% 267.34 C12H13NCH3SO3H C#CCNC1CCC2=CC=CC=C12 Ambient Ambient 20.6° Freely soluble in water, methanol and ethanol. "Naoi M, Maruyama W, Inaba-Hasegawa K. Revelation in the neuroprotective functions of rasagiline and selegiline: the induction of distinct genes by different mechanisms. Expert Rev Neurother. 2013 Jun;13(6):671-84. PMID: 23739004.

Naoi M, Maruyama W, Yi H. Rasagiline prevents apoptosis induced by PK11195, a ligand of the outer membrane translocator protein (18 kDa), in SH-SY5Y cells through suppression of cytochrome c release from mitochondria. J Neural Transm. 2013 Nov;120(11):1539-51. PMID: 23681678.

Inaba-Hasegawa K, Akao Y, Maruyama W, et al. Type A monoamine oxidase is associated with induction of neuroprotective Bcl-2 by rasagiline, an inhibitor of type B monoamine oxidase. J Neural Transm. 2012 Apr;119(4):405-14. PMID: 22065207.

Weinreb O, Amit T, Bar-Am O, et al. Induction of neurotrophic factors GDNF and BDNF associated with the mechanism of neurorescue action of rasagiline and ladostigil: new insights and implications for therapy. Ann N Y Acad Sci. 2007 Dec;1122:155-68. PMID: 18077571.

" Not dangerous goods.

LKT R0272 Rasagiline Mesylate 250 mg 335 MAO-A/B inhibitor. (R)-N-2-Propynyl-1-indanamine mesylate 161735-79-1 ≥98% 267.34 C12H13NCH3SO3H C#CCNC1CCC2=CC=CC=C12 Ambient Ambient 20.6° Freely soluble in water, methanol and ethanol. "Naoi M, Maruyama W, Inaba-Hasegawa K. Revelation in the neuroprotective functions of rasagiline and selegiline: the induction of distinct genes by different mechanisms. Expert Rev Neurother. 2013 Jun;13(6):671-84. PMID: 23739004.

Naoi M, Maruyama W, Yi H. Rasagiline prevents apoptosis induced by PK11195, a ligand of the outer membrane translocator protein (18 kDa), in SH-SY5Y cells through suppression of cytochrome c release from mitochondria. J Neural Transm. 2013 Nov;120(11):1539-51. PMID: 23681678.

Inaba-Hasegawa K, Akao Y, Maruyama W, et al. Type A monoamine oxidase is associated with induction of neuroprotective Bcl-2 by rasagiline, an inhibitor of type B monoamine oxidase. J Neural Transm. 2012 Apr;119(4):405-14. PMID: 22065207.

Weinreb O, Amit T, Bar-Am O, et al. Induction of neurotrophic factors GDNF and BDNF associated with the mechanism of neurorescue action of rasagiline and ladostigil: new insights and implications for therapy. Ann N Y Acad Sci. 2007 Dec;1122:155-68. PMID: 18077571.

" Not dangerous goods.

LKT N5550 Nomilin 100 mg 345.8 Triterpene found in species of Citrus; HIV-1 protease and aromatase inhibitor. 1-(3-Furyl)decaydro-11-hydroxy-4b,7,7-11a,13a- pentamethyloxireno(4,4a)-2-benzopyrano[6,5-g]- (2)benzoxepin-3,5,9(3aH,4bH,6H)-trione acetate 1-(Acetyloxy)-1,2-dihydroobacunoic acid ε-lactone 1063-77-0 ≥98% 514.56 C28H34O9 CC(=O)OC1CC(=O)OC(C2C1(C3CCC4(C(OC(=O)C5C4(C3(C(=O)C2)C)O5)C6=COC=C6)C)C)(C)C Ambient Ambient Soluble in acetone. "Sato R. Nomilin as an anti-obesity and anti-hyperglycemic agent. Vitam Horm. 2013;91:425-39. PMID: 23374727.

Kim J, Jayaprakasha GK, Patil BS. Limonoids and their anti-proliferative and anti-aromatase properties in human breast cancer cells. Food Funct. 2013 Feb;4(2):258-65. PMID: 23117440.

Pratheeshkumar P, Kuttan G. Nomilin inhibits tumor-specific angiogenesis by downregulating VEGF, NO and proinflammatory cytokine profile and also by inhibiting the activation of MMP-2 and MMP-9. Eur J Pharmacol. 2011 Oct 15;668(3):450-8. PMID: 21839074.

Ono E, Inoue J, Hashidume T, et al. Anti-obesity and anti-hyperglycemic effects of the dietary citrus limonoid nomilin in mice fed a high-fat diet. Biochem Biophys Res Commun. 2011 Jul 8;410(3):677-81. PMID: 21693102.

Perez JL, Jayaprakasha GK, Cadena A, et al. In vivo induction of phase II detoxifying enzymes, glutathione transferase and quinone reductase by citrus triterpenoids. BMC Complement Altern Med. 2010 Sep 17;10:51. PMID: 20846448.

Battinelli L, Mengoni F, Lichtner M, et al. Effect of limonin and nomilin on HIV-1 replication on infected human mononuclear cells. Planta Med. 2003 Oct;69(10):910-3. PMID: 14648393.

Raphael TJ, Kuttan G. Effect of naturally occurring triterpenoids glycyrrhizic acid, ursolic acid, oleanolic acid and nomilin on the immune system. Phytomedicine. 2003;10(6-7):483-9. PMID: 13678231.

" Not dangerous goods.

LKT N5550 Nomilin 500 mg 1195.2 Triterpene found in species of Citrus; HIV-1 protease and aromatase inhibitor. 1-(3-Furyl)decaydro-11-hydroxy-4b,7,7-11a,13a- pentamethyloxireno(4,4a)-2-benzopyrano[6,5-g]- (2)benzoxepin-3,5,9(3aH,4bH,6H)-trione acetate 1-(Acetyloxy)-1,2-dihydroobacunoic acid ε-lactone 1063-77-0 ≥98% 514.56 C28H34O9 CC(=O)OC1CC(=O)OC(C2C1(C3CCC4(C(OC(=O)C5C4(C3(C(=O)C2)C)O5)C6=COC=C6)C)C)(C)C Ambient Ambient Soluble in acetone. "Sato R. Nomilin as an anti-obesity and anti-hyperglycemic agent. Vitam Horm. 2013;91:425-39. PMID: 23374727.

Kim J, Jayaprakasha GK, Patil BS. Limonoids and their anti-proliferative and anti-aromatase properties in human breast cancer cells. Food Funct. 2013 Feb;4(2):258-65. PMID: 23117440.

Pratheeshkumar P, Kuttan G. Nomilin inhibits tumor-specific angiogenesis by downregulating VEGF, NO and proinflammatory cytokine profile and also by inhibiting the activation of MMP-2 and MMP-9. Eur J Pharmacol. 2011 Oct 15;668(3):450-8. PMID: 21839074.

Ono E, Inoue J, Hashidume T, et al. Anti-obesity and anti-hyperglycemic effects of the dietary citrus limonoid nomilin in mice fed a high-fat diet. Biochem Biophys Res Commun. 2011 Jul 8;410(3):677-81. PMID: 21693102.

Perez JL, Jayaprakasha GK, Cadena A, et al. In vivo induction of phase II detoxifying enzymes, glutathione transferase and quinone reductase by citrus triterpenoids. BMC Complement Altern Med. 2010 Sep 17;10:51. PMID: 20846448.

Battinelli L, Mengoni F, Lichtner M, et al. Effect of limonin and nomilin on HIV-1 replication on infected human mononuclear cells. Planta Med. 2003 Oct;69(10):910-3. PMID: 14648393.

Raphael TJ, Kuttan G. Effect of naturally occurring triterpenoids glycyrrhizic acid, ursolic acid, oleanolic acid and nomilin on the immune system. Phytomedicine. 2003;10(6-7):483-9. PMID: 13678231.

" Not dangerous goods.

LKT R0253 Ranitidine Hydrochloride 1 g 30 Histamine H2 inverse agonist. N-[2-[[[-5-[(Dimethylamino)methyl]-2-furanyl]- methyl]thio]ethyl]-N'-methyl-2-nitro-1,1-ethenediamine Azantac; Melfx; Noctone; Ranidil; Taural; Trigger; Ulcex; Zantac; Zantic 66357-59-3 ≥98% 350.86 C13H22N4O3SHCl CNC(=C[N+](=O)[O-])NCCSCC1=CC=C(O1)CN(C)C.Cl Ambient Ambient Soluble in acetic acid, water and methanol. Slightly soluble in ethanol. Practically insoluble in chloroform. "Alonso N, Monczor F, Echeverría E, et al. Signal transduction mechanism of biased ligands at histamine H2 receptors. Biochem J. 2014 Apr 1;459(1):117-26. PMID: 24417223.

Rodriguez-Stanley S, Ciociola AA, Zubaidi S, et al. A single dose of ranitidine 150 mg modulates oesophageal acid sensitivity in patients with functional heartburn. Aliment Pharmacol Ther. 2004 Nov 1;20(9):975-82. PMID: 15521845.

" Xn Not dangerous goods.

LKT R0253 Ranitidine Hydrochloride 5 g 83.9 Histamine H2 inverse agonist. N-[2-[[[-5-[(Dimethylamino)methyl]-2-furanyl]- methyl]thio]ethyl]-N'-methyl-2-nitro-1,1-ethenediamine Azantac; Melfa; Noctone; Ranidil; Taural; Trigger; Ulcex; Zantac; Zantic 66357-59-3 ≥98% 350.86 C13H22N4O3SHCl CNC(=C[N+](=O)[O-])NCCSCC1=CC=C(O1)CN(C)C.Cl Ambient Ambient Soluble in acetic acid, water and methanol. Slightly soluble in ethanol. Practically insoluble in chloroform. "Alonso N, Monczor F, Echeverría E, et al. Signal transduction mechanism of biased ligands at histamine H2 receptors. Biochem J. 2014 Apr 1;459(1):117-26. PMID: 24417223.

Rodriguez-Stanley S, Ciociola AA, Zubaidi S, et al. A single dose of ranitidine 150 mg modulates oesophageal acid sensitivity in patients with functional heartburn. Aliment Pharmacol Ther. 2004 Nov 1;20(9):975-82. PMID: 15521845.

" Xn Not dangerous goods.

LKT N5652 Nonactin 1 mg 37.5 Naturally-ocurring neurtral cyclic ionophore, metal ion carrier; oxidative phosphorylation uncoupler. 6833-84-7 ≥95%, TLC 736.93 C40H64O12 CC1CC2CCC(O2)C(C(=O)OC(CC3CCC(O3)C(C(=O)OC(CC4CCC(O4)C(C(=O)OC(CC5CCC(O5)C(C(=O)O1)C)C)C)C)C)C)C Ambient 4°C methanol, dichloromethane, ethyl acetate, DMSO "Lee JM, Kim JG, Kim TH, et al. Nonactin hinders intracellular glycosylation in virus-infected baby hamster kidney cells. Mol Med Rep. 2010 Jan-Feb;3(1):115-9. PMID: 21472209.

Bala S, Kombrabail MH, Prabhananda BS. Effect of phloretin on ionophore mediated electroneutral transmembrane translocations of H(+), K(+) and Na(+) in phospholipid vesicles. Biochim Biophys Acta. 2001 Feb 9;1510(1-2):258-69. PMID: 11342163.

Vareille G, Marion P, Kraus JL, et al. Sodium transport by an ionizable and a neutral carrier: effects of membrane structure on the apparent activation energy. Biochim Biophys Acta. 1993 Feb 23;1146(1):25-37. PMID: 8443224.

Ginsburg H, Stark G. Facilitated transport of di- and trinitrophenolate ions across lipid membranes by valinomycin and nonactin. Biochim Biophys Acta. 1976 Dec 14;455(3):685-700. PMID: 1036715.

" Xn Not dangerous goods.

LKT N5652 Nonactin 5 mg 75 Naturally-ocurring neurtral cyclic ionophore, metal ion carrier; oxidative phosphorylation uncoupler. 6833-84-7 ≥95%, TLC 736.93 C40H64O12 CC1CC2CCC(O2)C(C(=O)OC(CC3CCC(O3)C(C(=O)OC(CC4CCC(O4)C(C(=O)OC(CC5CCC(O5)C(C(=O)O1)C)C)C)C)C)C)C Ambient 4°C methanol, dichloromethane, ethyl acetate, DMSO "Lee JM, Kim JG, Kim TH, et al. Nonactin hinders intracellular glycosylation in virus-infected baby hamster kidney cells. Mol Med Rep. 2010 Jan-Feb;3(1):115-9. PMID: 21472209.

Bala S, Kombrabail MH, Prabhananda BS. Effect of phloretin on ionophore mediated electroneutral transmembrane translocations of H(+), K(+) and Na(+) in phospholipid vesicles. Biochim Biophys Acta. 2001 Feb 9;1510(1-2):258-69. PMID: 11342163.

Vareille G, Marion P, Kraus JL, et al. Sodium transport by an ionizable and a neutral carrier: effects of membrane structure on the apparent activation energy. Biochim Biophys Acta. 1993 Feb 23;1146(1):25-37. PMID: 8443224.

Ginsburg H, Stark G. Facilitated transport of di- and trinitrophenolate ions across lipid membranes by valinomycin and nonactin. Biochim Biophys Acta. 1976 Dec 14;455(3):685-700. PMID: 1036715.

" Xn Not dangerous goods.

LKT N5652 Nonactin 10 mg 134.9 Naturally-ocurring neurtral cyclic ionophore, metal ion carrier; oxidative phosphorylation uncoupler. 6833-84-7 ≥95%, TLC 736.93 C40H64O12 CC1CC2CCC(O2)C(C(=O)OC(CC3CCC(O3)C(C(=O)OC(CC4CCC(O4)C(C(=O)OC(CC5CCC(O5)C(C(=O)O1)C)C)C)C)C)C)C Ambient 4°C methanol, dichloromethane, ethyl acetate, DMSO "Lee JM, Kim JG, Kim TH, et al. Nonactin hinders intracellular glycosylation in virus-infected baby hamster kidney cells. Mol Med Rep. 2010 Jan-Feb;3(1):115-9. PMID: 21472209.

Bala S, Kombrabail MH, Prabhananda BS. Effect of phloretin on ionophore mediated electroneutral transmembrane translocations of H(+), K(+) and Na(+) in phospholipid vesicles. Biochim Biophys Acta. 2001 Feb 9;1510(1-2):258-69. PMID: 11342163.

Vareille G, Marion P, Kraus JL, et al. Sodium transport by an ionizable and a neutral  carrier: effects of membrane structure on the apparent activation energy. Biochim Biophys Acta. 1993 Feb 23;1146(1):25-37. PMID: 8443224.

Ginsburg H, Stark G. Facilitated transport of di- and trinitrophenolate ions across lipid membranes by valinomycin and nonactin. Biochim Biophys Acta. 1976 Dec 14;455(3):685-700. PMID: 1036715.

" Xn Not dangerous goods.

LKT R0251 Ranatensin R 1 mg 270.2 Peptide found in amphibians, neuromedin B analog. "

" 70572-93-9 ≥98% 2052.3 C90H134N30O24S CC(C)CC(C(=O)NC(CCCNC(=N)N)C(=O)NC(CCCNC(=N)N)C(=O)NC(CC1=CC=C(C=C1)O)C(=O)NC(CC(=O)N)C(=O)NC(CCC(=O)N)C(=O)NC(CC2=CNC3=CC=CC=C32)C(=O)NC(C)C(=O)NC(C(C)O)C(=O)NCC(=O)NC(CC4=CNC=N4)C(=O)NC(CC5=CC=CC=C5)C(=O)NC(CCSC)C(=O)N)NC(=O)C(C)NC(=O)C(C(C)O)NC(=O)C(CC(=O)N)NC(=O)C(CO)N Ambient -20°C Taché Y. Intracisternal bombesin induced inhibition of gastric secretion is not mediated through prostaglandin or opioid pathways. Peptides. 1985;6 Suppl 3:69-73. PMID: 3868774. Not dangerous goods.

LKT R0251 Ranatensin R 2 mg 459.1 Peptide found in amphibians, neuromedin B analog. "

" 70572-93-9 ≥98% 2052.3 C90H134N30O24S CC(C)CC(C(=O)NC(CCCNC(=N)N)C(=O)NC(CCCNC(=N)N)C(=O)NC(CC1=CC=C(C=C1)O)C(=O)NC(CC(=O)N)C(=O)NC(CCC(=O)N)C(=O)NC(CC2=CNC3=CC=CC=C32)C(=O)NC(C)C(=O)NC(C(C)O)C(=O)NCC(=O)NC(CC4=CNC=N4)C(=O)NC(CC5=CC=CC=C5)C(=O)NC(CCSC)C(=O)N)NC(=O)C(C)NC(=O)C(C(C)O)NC(=O)C(CC(=O)N)NC(=O)C(CO)N Ambient -20°C Taché Y. Intracisternal bombesin induced inhibition of gastric secretion is not mediated through prostaglandin or opioid pathways. Peptides. 1985;6 Suppl 3:69-73. PMID: 3868774. Not dangerous goods.

LKT R0251 Ranatensin R 5 mg 810.1 Peptide found in amphibians, neuromedin B analog. "

" 70572-93-9 ≥98% 2052.3 C90H134N30O24S CC(C)CC(C(=O)NC(CCCNC(=N)N)C(=O)NC(CCCNC(=N)N)C(=O)NC(CC1=CC=C(C=C1)O)C(=O)NC(CC(=O)N)C(=O)NC(CCC(=O)N)C(=O)NC(CC2=CNC3=CC=CC=C32)C(=O)NC(C)C(=O)NC(C(C)O)C(=O)NCC(=O)NC(CC4=CNC=N4)C(=O)NC(CC5=CC=CC=C5)C(=O)NC(CCSC)C(=O)N)NC(=O)C(C)NC(=O)C(C(C)O)NC(=O)C(CC(=O)N)NC(=O)C(CO)N Ambient -20°C Taché Y. Intracisternal bombesin induced inhibition of gastric secretion is not mediated through prostaglandin or opioid pathways. Peptides. 1985;6 Suppl 3:69-73. PMID: 3868774. Not dangerous goods.

LKT N5655 Nonoxynol-9 50 g 57.8 Nonoxynol surfactant. α-(4-Nonylphenyl)-ω-hydroxypoly(oxy-1,2-ethane- diyl) C-Film; Encare; Intercept; Semicid; Staycept; Tergitol TP-9 26571-11-9 ≥98% 616.82 C33H60O10 CCCCCCCCCC1=CC=C(C=C1)OCCOCCOCCOCCOCCOCCOCCOCCOCCO Ambient Ambient Soluble in water, ethanol, ethylene glycol, or xylene. "Hillier SL, Moench T, Shattock R, et al. In vitro and in vivo: the story of nonoxynol 9. J Acquir Immune Defic Syndr. 2005 May 1;39(1):1-8. PMID: 15851907.

Maikhuri JP, Dwivedi AK, Dhar JD, et al. Mechanism of action of some acrylophenones, quinolines and dithiocarbamate as potent, non-detergent spermicidal agents. Contraception. 2003 May;67(5):403-8. PMID: 12742565.

" "UN number: 3082     Class: 9     Packing Group: III

Proper shipping name: Environmentally hazardous substance, liquid, n.o.s. (Nonoxynol-9)

Marine pollutant: Yes"

LKT N5655 Nonoxynol-9 100 g 101.1 Nonoxynol surfactant. α-(4-Nonylphenyl)-ω-hydroxypoly(oxy-1,2-ethane- diyl) C-Film; Encare; Intercept; Semicid; Staycept; Tergitol TP-9 26571-11-9 ≥98% 616.82 C33H60O10 CCCCCCCCCC1=CC=C(C=C1)OCCOCCOCCOCCOCCOCCOCCOCCOCCO Ambient Ambient Soluble in water, ethanol, ethylene glycol, or xylene. "Hillier SL, Moench T, Shattock R, et al. In vitro and in vivo: the story of nonoxynol 9. J Acquir Immune Defic Syndr. 2005 May 1;39(1):1-8. PMID: 15851907.

Maikhuri JP, Dwivedi AK, Dhar JD, et al. Mechanism of action of some acrylophenones, quinolines and dithiocarbamate as potent, non-detergent spermicidal agents. Contraception. 2003 May;67(5):403-8. PMID: 12742565.

" "UN number: 3082     Class: 9     Packing Group: III

Proper shipping name: Environmentally hazardous substance, liquid, n.o.s. (Nonoxynol-9)

Marine pollutant: Yes"

LKT R0250 Ranatensin 1 mg 72.1 Peptide found in amphibians. Pyroglutamyl-valyl-prolyl-glutaminyl-tryptophyl-alanyl-valyl-glycyl-histidyl-phenylalanyl-methionylamide 29451-71-6 ≥98% 1281.5 C61H85N16O13S CC(C)C(C(=O)NCC(=O)NC(CC1=CN=CN1)C(=O)NC(CC2=CC=CC=C2)C(=O)NC(CCSC)C(=O)N)NC(=O)C(C)NC(=O)C(CC3=CNC4=CC=CC=C43)NC(=O)C(CCC(=O)N)NC(=O)C5CCCN5C(=O)C(C(C)C)NC(=O)C6CCC(=O)N6 Ambient -20°C Soluble in water. "Chandan R, Newell SM, Brown DR. Actions of gastrin-releasing peptide and related mammalian and amphibian peptides on ion transport in the porcine proximal jejunum. Regul Pept. 1988 Oct;23(1):1-14. Erratum in: Regul Pept 1989 Mar;24(3):312.  PMID: 3238049.

Modlin IM, Lamers CB, Walsh JH. Stimulation of canine pancreatic polypeptide, gastrin, and gastric acid secretion by ranatensin, litorin, bombesin nonapeptide and substance P. Regul Pept. 1981 Jan;1(4):279-88. PMID: 6166964.

" Not dangerous goods.

LKT R0250 Ranatensin 2 mg 120 Peptide found in amphibians. Pyroglutamyl-valyl-prolyl-glutaminyl-tryptophyl-alanyl-valyl-glycyl-histidyl-phenylalanyl-methionylamide 29451-71-6 ≥98% 1281.5 C61H85N16O13S CC(C)C(C(=O)NCC(=O)NC(CC1=CN=CN1)C(=O)NC(CC2=CC=CC=C2)C(=O)NC(CCSC)C(=O)N)NC(=O)C(C)NC(=O)C(CC3=CNC4=CC=CC=C43)NC(=O)C(CCC(=O)N)NC(=O)C5CCCN5C(=O)C(C(C)C)NC(=O)C6CCC(=O)N6 Ambient -20°C Soluble in water. "Chandan R, Newell SM, Brown DR. Actions of gastrin-releasing peptide and related mammalian and amphibian peptides on ion transport in the porcine proximal jejunum. Regul Pept. 1988 Oct;23(1):1-14. Erratum in: Regul Pept 1989 Mar;24(3):312.  PMID: 3238049.

Modlin IM, Lamers CB, Walsh JH. Stimulation of canine pancreatic polypeptide, gastrin, and gastric acid secretion by ranatensin, litorin, bombesin nonapeptide and substance P. Regul Pept. 1981 Jan;1(4):279-88. PMID: 6166964.

" Not dangerous goods.

LKT R0250 Ranatensin 5 mg 216.1 Peptide found in amphibians. Pyroglutamyl-valyl-prolyl-glutaminyl-tryptophyl-alanyl-valyl-glycyl-histidyl-phenylalanyl-methionylamide 29451-71-6 ≥98% 1281.5 C61H85N16O13S CC(C)C(C(=O)NCC(=O)NC(CC1=CN=CN1)C(=O)NC(CC2=CC=CC=C2)C(=O)NC(CCSC)C(=O)N)NC(=O)C(C)NC(=O)C(CC3=CNC4=CC=CC=C43)NC(=O)C(CCC(=O)N)NC(=O)C5CCCN5C(=O)C(C(C)C)NC(=O)C6CCC(=O)N6 Ambient -20°C Soluble in water. "Chandan R, Newell SM, Brown DR. Actions of gastrin-releasing peptide and related mammalian and amphibian peptides on ion transport in the porcine proximal jejunum. Regul Pept. 1988 Oct;23(1):1-14. Erratum in: Regul Pept 1989 Mar;24(3):312.  PMID: 3238049.

Modlin IM, Lamers CB, Walsh JH. Stimulation of canine pancreatic polypeptide, gastrin, and gastric acid secretion by ranatensin, litorin, bombesin nonapeptide and substance P. Regul Pept. 1981 Jan;1(4):279-88. PMID: 6166964.

" Not dangerous goods.

LKT R0249 Ramipril 500 mg 115.5 ACE inhibitor. [2S,3aS,6aS]-1-[(2S)-2-[[(1S)-1-(Ethoxycarbonyl)-3- phenylpropyl]amino]-1-oxopropyl]octahydrocyclo- penta[b]pyrrole-2-carboxylic acid Tritace; Ramace; Unipril; Vesdil 87333-19-5 ≥98% 416.51 C23H32N2O5 CCOC(=O)C(CCC1=CC=CC=C1)NC(C)C(=O)N2C3CCCC3CC2C(=O)O Ambient Ambient Soluble in DMSO (10mg/mL).and  Acetonitrile "Zhong Y, Cao P, Tong C, et al. Effect of ramipril on the electrophysiological characteristics of ventricular myocardium after myocardial infarction in rabbits. J Cardiovasc Med (Hagerstown). 2012 May;13(5):313-8. PMID: 22441218.

Chen CY, Lee BC, Hsu HC, et al. A proteomic study of the effects of ramipril on post-infarction left ventricular remodelling in the rabbit. Eur J Heart Fail. 2008 Aug;10(8):740-8. PMID: 18583185.

Dupuis F, Atkinson J, Limiñana P, et al. Comparative effects of the angiotensin II receptor blocker, telmisartan, and the angiotensin-converting enzyme inhibitor, ramipril, on cerebrovascular structure in spontaneously hypertensive rats. J Hypertens. 2005 May;23(5):1061-6. PMID: 15834293.

" Xi Not dangerous goods.

LKT R0249 Ramipril 1 g 180.2 ACE inhibitor. [2S,3aS,6aS]-1-[(2S)-2-[[(1S)-1-(Ethoxycarbonyl)-3- phenylpropyl]amino]-1-oxopropyl]octahydrocyclo- penta[b]pyrrole-2-carboxylic acid Tritace; Ramace; Unipril; Vesdil 87333-19-5 ≥98% 416.51 C23H32N2O5 CCOC(=O)C(CCC1=CC=CC=C1)NC(C)C(=O)N2C3CCCC3CC2C(=O)O Ambient Ambient Soluble in DMSO (10mg/mL).and  Acetonitrile "Zhong Y, Cao P, Tong C, et al. Effect of ramipril on the electrophysiological characteristics of ventricular myocardium after myocardial infarction in rabbits. J Cardiovasc Med (Hagerstown). 2012 May;13(5):313-8. PMID: 22441218.

Chen CY, Lee BC, Hsu HC, et al. A proteomic study of the effects of ramipril on post-infarction left ventricular remodelling in the rabbit. Eur J Heart Fail. 2008 Aug;10(8):740-8. PMID: 18583185.

Dupuis F, Atkinson J, Limiñana P, et al. Comparative effects of the angiotensin II receptor blocker, telmisartan, and the angiotensin-converting enzyme inhibitor, ramipril, on cerebrovascular structure in spontaneously hypertensive rats. J Hypertens. 2005 May;23(5):1061-6. PMID: 15834293.

" Xi Not dangerous goods.

LKT R0249 Ramipril 5 g 693.2 ACE inhibitor. [2S,3aS,6aS]-1-[(2S)-2-[[(1S)-1-(Ethoxycarbonyl)-3- phenylpropyl]amino]-1-oxopropyl]octahydrocyclo- penta[b]pyrrole-2-carboxylic acid Tritace; Ramace; Unipril; Vesdil 87333-19-5 ≥98% 416.51 C23H32N2O5 CCOC(=O)C(CCC1=CC=CC=C1)NC(C)C(=O)N2C3CCCC3CC2C(=O)O Ambient Ambient Soluble in DMSO (10mg/mL).and  Acetonitrile "Zhong Y, Cao P, Tong C, et al. Effect of ramipril on the electrophysiological characteristics of ventricular myocardium after myocardial infarction in rabbits. J Cardiovasc Med (Hagerstown). 2012 May;13(5):313-8. PMID: 22441218.

Chen CY, Lee BC, Hsu HC, et al. A proteomic study of the effects of ramipril on post-infarction left ventricular remodelling in the rabbit. Eur J Heart Fail. 2008 Aug;10(8):740-8. PMID: 18583185.

Dupuis F, Atkinson J, Limiñana P, et al. Comparative effects of the angiotensin II receptor blocker, telmisartan, and the angiotensin-converting enzyme inhibitor, ramipril, on cerebrovascular structure in spontaneously hypertensive rats. J Hypertens. 2005 May;23(5):1061-6. PMID: 15834293.

" Xi Not dangerous goods.

LKT R0245 Raltitrexed 10 mg 83.7 Folate analog; thymidylate synthase inhibitor. (2S)-2-[[5-[methyl-[(2-methyl-4-oxo-1H-quinazolin-6-yl)methyl]amino]thiophene-2-carbonyl]amino]pentanedioic acid 112887-68-0 ≥98% 458.49 C21H22N4O6S CC1=NC(=O)C2=C(N1)C=CC(=C2)CN(C)C3=CC=C(S3)C(=O)NC(CCC(=O)O)C(=O)O Ambient Ambient "Avallone A, Gennaro ED, Silvestro L, et al. Targeting thymidylate synthase in colorectal cancer: critical re-evaluation and emerging therapeutic role of raltitrexed. Expert Opin Drug Saf. 2014 Jan;13(1):113-29. PMID: 24093908.

Van Cutsem E, Cunningham D, Maroun J, et al. Raltitrexed: current clinical status and future directions. Ann Oncol. 2002 Apr;13(4):513-22. PMID: 12056700.

" Xi "UN number: 2811     Class: 6.1     Packing group: III

Proper shipping name: Toxic solid, organic, n.o.s. (Raltitrexed)

Marine pollutant: no     Poison inhalation hazard: no"

LKT R0245 Raltitrexed 25 mg 167.4 Folate analog; thymidylate synthase inhibitor. (2S)-2-[[5-[methyl-[(2-methyl-4-oxo-1H-quinazolin-6-yl)methyl]amino]thiophene-2-carbonyl]amino]pentanedioic acid 112887-68-0 ≥98% 458.49 C21H22N4O6S CC1=NC(=O)C2=C(N1)C=CC(=C2)CN(C)C3=CC=C(S3)C(=O)NC(CCC(=O)O)C(=O)O Ambient Ambient "Avallone A, Gennaro ED, Silvestro L, et al. Targeting thymidylate synthase in colorectal cancer: critical re-evaluation and emerging therapeutic role of raltitrexed. Expert Opin Drug Saf. 2014 Jan;13(1):113-29. PMID: 24093908.

Van Cutsem E, Cunningham D, Maroun J, et al. Raltitrexed: current clinical status and future directions. Ann Oncol. 2002 Apr;13(4):513-22. PMID: 12056700.

" Xi "UN number: 2811     Class: 6.1     Packing group: III

Proper shipping name: Toxic solid, organic, n.o.s. (Raltitrexed)

Marine pollutant: no     Poison inhalation hazard: no"

LKT R0245 Raltitrexed 100 mg 502.3 Folate analog; thymidylate synthase inhibitor. (2S)-2-[[5-[methyl-[(2-methyl-4-oxo-1H-quinazolin-6-yl)methyl]amino]thiophene-2-carbonyl]amino]pentanedioic acid 112887-68-0 ≥98% 458.49 C21H22N4O6S CC1=NC(=O)C2=C(N1)C=CC(=C2)CN(C)C3=CC=C(S3)C(=O)NC(CCC(=O)O)C(=O)O Ambient Ambient "Avallone A, Gennaro ED, Silvestro L, et al. Targeting thymidylate synthase in colorectal cancer: critical re-evaluation and emerging therapeutic role of raltitrexed. Expert Opin Drug Saf. 2014 Jan;13(1):113-29. PMID: 24093908.

Van Cutsem E, Cunningham D, Maroun J, et al. Raltitrexed: current clinical status and future directions. Ann Oncol. 2002 Apr;13(4):513-22. PMID: 12056700.

" Xi "UN number: 2811     Class: 6.1     Packing group: III

Proper shipping name: Toxic solid, organic, n.o.s. (Raltitrexed)

Marine pollutant: no     Poison inhalation hazard: no"

LKT N5669 Nordihydroguaiaretic Acid 500 mg 40.7 Phenol found in the creosote bush; 5-lipoxygenase, AChR, BChE, mTORC1 inhibitor. 4,4-(2,3-Dimethyl-1,4butanediyl)bis[1,2-benzenediol] NDGA; Dihydronorguaiaretic acid; Pyrocatechol, 4,4'-(2,3-dimethyltetramethylene)di- 500-38-9 ≥97% 302.36 C18H22O4 CC(CC1=CC(=C(C=C1)O)O)C(C)CC2=CC(=C(C=C2)O)O Ambient Ambient Soluble in ethanol, methanol, or hot water. "Hernández-Damián J, Andérica-Romero AC, Pedraza-Chaverri J. Paradoxical cellular effects and biological role of the multifaceted compound nordihydroguaiaretic Acid. Arch Pharm (Weinheim). 2014 Oct;347(10):685-97. PMID: 25100573.

Soto-Acosta R, Bautista-Carbajal P, Syed GH, et al. Nordihydroguaiaretic acid (NDGA) inhibits replication and viral morphogenesis of dengue virus. Antiviral Res. 2014 Sep;109:132-40. PMID: 25017471.

Harrison DE, Strong R, Allison DB, et al. Acarbose, 17-α-estradiol, and nordihydroguaiaretic acid extend mouse lifespan preferentially in males. Aging Cell. 2014 Apr;13(2):273-82. PMID: 24245565.

Yang X, Cui W, Yu S, et al. A synthetic dl-nordihydroguaiaretic acid (Nordy), inhibits angiogenesis, invasion and proliferation of glioma stem cells within a zebrafish xenotransplantation model. PLoS One. 2014 Jan 15;9(1):e85759. PMID: 24454929.

Szwajgier D. Anticholinesterase activity of phenolic acids and their derivatives. Z Naturforsch C. 2013 Mar-Apr;68(3-4):125-32. PMID: 23819308.

Batallán G, Torre R, Flores F, et al. Larvicidal activity of crude extracts from Larrea cuneifolia (Zygophyllaceae) and of its metabolite nordihydroguaiaretic acid against the vector Culex quinquefasciatus (Diptera: Culicidae). Rev Soc Bras Med Trop. 2013 Jan-Feb;46(1):84-7. PMID: 23563831.

Zhang H, Shen WJ, Cortez Y, et al. Nordihydroguaiaretic acid improves metabolic dysregulation and aberrant hepatic lipid metabolism in mice by both PPARα-dependent and -independent pathways. Am J Physiol Gastrointest Liver Physiol. 2013 Jan 1;304(1):G72-86. PMID: 23104557.

Martino RF, Davicino RC, Mattar MA, et al. Macrophages activation by a purified fraction, free of nordihydroguaiaretic acid (NDGA), from Larrea divaricata Cav. as a potential novel therapy against Candida albicans. Immunopharmacol Immunotoxicol. 2012 Dec;34(6):975-82. PMID: 22551492.

Li YJ, Kukita A, Watanabe T, et al. Nordihydroguaiaretic acid inhibition of NFATc1 suppresses osteoclastogenesis and arthritis bone destruction in rats. Lab Invest. 2012 Dec;92(12):1777-87. PMID: 23044922.

Zhang Y, Xu S, Lin J, et al. mTORC1 is a target of nordihydroguaiaretic acid to prevent breast tumor growth in vitro and in vivo. Breast Cancer Res Treat. 2012 Nov;136(2):379-88. PMID: 23053656.

Kim HY, Goo JH, Joo YA, et al. Impact on inflammation and recovery of skin barrier by nordihydroguaiaretic Acid as a protease-activated receptor 2 antagonist. Biomol Ther (Seoul). 2012 Sep;20(5):463-9. PMID: 24009835.

" Xn, Xi Not dangerous goods.

LKT N5669 Nordihydroguaiaretic Acid 1 g 70.7 Phenol found in the creosote bush; 5-lipoxygenase, AChR, BChE, mTORC1 inhibitor. 4,4-(2,3-Dimethyl-1,4butanediyl)bis[1,2-benzenediol] NDGA; Dihydronorguaiaretic acid; Pyrocatechol, 4,4'-(2,3-dimethyltetramethylene)di- 500-38-9 ≥97% 302.36 C18H22O4 CC(CC1=CC(=C(C=C1)O)O)C(C)CC2=CC(=C(C=C2)O)O Ambient Ambient Soluble in ethanol, methanol, or hot water. "Hernández-Damián J, Andérica-Romero AC, Pedraza-Chaverri J. Paradoxical cellular effects and biological role of the multifaceted compound nordihydroguaiaretic Acid. Arch Pharm (Weinheim). 2014 Oct;347(10):685-97. PMID: 25100573.

Soto-Acosta R, Bautista-Carbajal P, Syed GH, et al. Nordihydroguaiaretic acid (NDGA) inhibits replication and viral morphogenesis of dengue virus. Antiviral Res. 2014 Sep;109:132-40. PMID: 25017471.

Harrison DE, Strong R, Allison DB, et al. Acarbose, 17-α-estradiol, and nordihydroguaiaretic acid extend mouse lifespan preferentially in males. Aging Cell. 2014 Apr;13(2):273-82. PMID: 24245565.

Yang X, Cui W, Yu S, et al. A synthetic dl-nordihydroguaiaretic acid (Nordy), inhibits angiogenesis, invasion and proliferation of glioma stem cells within a zebrafish xenotransplantation model. PLoS One. 2014 Jan 15;9(1):e85759. PMID: 24454929.

Szwajgier D. Anticholinesterase activity of phenolic acids and their derivatives. Z Naturforsch C. 2013 Mar-Apr;68(3-4):125-32. PMID: 23819308.

Batallán G, Torre R, Flores F, et al. Larvicidal activity of crude extracts from Larrea cuneifolia (Zygophyllaceae) and of its metabolite nordihydroguaiaretic acid against the vector Culex quinquefasciatus (Diptera: Culicidae). Rev Soc Bras Med Trop. 2013 Jan-Feb;46(1):84-7. PMID: 23563831.

Zhang H, Shen WJ, Cortez Y, et al. Nordihydroguaiaretic acid improves metabolic dysregulation and aberrant hepatic lipid metabolism in mice by both PPARα-dependent and -independent pathways. Am J Physiol Gastrointest Liver Physiol. 2013 Jan 1;304(1):G72-86. PMID: 23104557.

Martino RF, Davicino RC, Mattar MA, et al. Macrophages activation by a purified fraction, free of nordihydroguaiaretic acid (NDGA), from Larrea divaricata Cav. as a potential novel therapy against Candida albicans. Immunopharmacol Immunotoxicol. 2012 Dec;34(6):975-82. PMID: 22551492.

Li YJ, Kukita A, Watanabe T, et al. Nordihydroguaiaretic acid inhibition of NFATc1 suppresses osteoclastogenesis and arthritis bone destruction in rats. Lab Invest. 2012 Dec;92(12):1777-87. PMID: 23044922.

Zhang Y, Xu S, Lin J, et al. mTORC1 is a target of nordihydroguaiaretic acid to prevent breast tumor growth in vitro and in vivo. Breast Cancer Res Treat. 2012 Nov;136(2):379-88. PMID: 23053656.

Kim HY, Goo JH, Joo YA, et al. Impact on inflammation and recovery of skin barrier by nordihydroguaiaretic Acid as a protease-activated receptor 2 antagonist. Biomol Ther (Seoul). 2012 Sep;20(5):463-9. PMID: 24009835.

" Xn, Xi Not dangerous goods.

LKT N5669 Nordihydroguaiaretic Acid 5 g 298.9 Phenol found in the creosote bush; 5-lipoxygenase, AChR, BChE, mTORC1 inhibitor. 4,4-(2,3-Dimethyl-1,4butanediyl)bis[1,2-benzenediol] NDGA; Dihydronorguaiaretic acid; Pyrocatechol, 4,4'-(2,3-dimethyltetramethylene)di- 500-38-9 ≥97% 302.36 C18H22O4 CC(CC1=CC(=C(C=C1)O)O)C(C)CC2=CC(=C(C=C2)O)O Ambient Ambient Soluble in ethanol, methanol, or hot water. "Hernández-Damián J, Andérica-Romero AC, Pedraza-Chaverri J. Paradoxical cellular effects and biological role of the multifaceted compound nordihydroguaiaretic Acid. Arch Pharm (Weinheim). 2014 Oct;347(10):685-97. PMID: 25100573.

Soto-Acosta R, Bautista-Carbajal P, Syed GH, et al. Nordihydroguaiaretic acid (NDGA) inhibits replication and viral morphogenesis of dengue virus. Antiviral Res. 2014 Sep;109:132-40. PMID: 25017471.

Harrison DE, Strong R, Allison DB, et al. Acarbose, 17-α-estradiol, and nordihydroguaiaretic acid extend mouse lifespan preferentially in males. Aging Cell. 2014 Apr;13(2):273-82. PMID: 24245565.

Yang X, Cui W, Yu S, et al. A synthetic dl-nordihydroguaiaretic acid (Nordy), inhibits angiogenesis, invasion and proliferation of glioma stem cells within a zebrafish xenotransplantation model. PLoS One. 2014 Jan 15;9(1):e85759. PMID: 24454929.

Szwajgier D. Anticholinesterase activity of phenolic acids and their derivatives. Z Naturforsch C. 2013 Mar-Apr;68(3-4):125-32. PMID: 23819308.

Batallán G, Torre R, Flores F, et al. Larvicidal activity of crude extracts from Larrea cuneifolia (Zygophyllaceae) and of its metabolite nordihydroguaiaretic acid against the vector Culex quinquefasciatus (Diptera: Culicidae). Rev Soc Bras Med Trop. 2013 Jan-Feb;46(1):84-7. PMID: 23563831.

Zhang H, Shen WJ, Cortez Y, et al. Nordihydroguaiaretic acid improves metabolic dysregulation and aberrant hepatic lipid metabolism in mice by both PPARα-dependent and -independent pathways. Am J Physiol Gastrointest Liver Physiol. 2013 Jan 1;304(1):G72-86. PMID: 23104557.

Martino RF, Davicino RC, Mattar MA, et al. Macrophages activation by a purified fraction, free of nordihydroguaiaretic acid (NDGA), from Larrea divaricata Cav. as a potential novel therapy against Candida albicans. Immunopharmacol Immunotoxicol. 2012 Dec;34(6):975-82. PMID: 22551492.

Li YJ, Kukita A, Watanabe T, et al. Nordihydroguaiaretic acid inhibition of NFATc1 suppresses osteoclastogenesis and arthritis bone destruction in rats. Lab Invest. 2012 Dec;92(12):1777-87. PMID: 23044922.

Zhang Y, Xu S, Lin J, et al. mTORC1 is a target of nordihydroguaiaretic acid to prevent breast tumor growth in vitro and in vivo. Breast Cancer Res Treat. 2012 Nov;136(2):379-88. PMID: 23053656.

Kim HY, Goo JH, Joo YA, et al. Impact on inflammation and recovery of skin barrier by nordihydroguaiaretic Acid as a protease-activated receptor 2 antagonist. Biomol Ther (Seoul). 2012 Sep;20(5):463-9. PMID: 24009835.

" Xn, Xi Not dangerous goods.

LKT N5766 Norepinephrine Bitartrate Monohydrate 500 mg 95.1 Endogenous hormone and neurotransmitter involved in sympathetic nervous system activity, reward, feeding, and other behaviors; α/β-adrenergic agonist. 4-[(1R)-2-Amino-1-hydroxyethyl]-1,2-benzenediol d-Bitartrate Norepinephrine d-Bitartrate; Levarterenol bitartrate 108341-18-0 ≥98% 337.28 C8H11NO3 C4H6O6 H2O C1=CC(=C(C=C1C(CN)O)O)O.C(C(C(=O)O)O)(C(=O)O)O.O Ambient Ambient Soluble in water (400 mg/mL).  Slightly soluble in ethanol (3 mg/mL). "Lavine JA, Sang Y, Wang S, et al. Attenuation of choroidal neovascularization by β(2)-adrenoreceptor antagonism. JAMA Ophthalmol. 2013 Mar;131(3):376-82. PMID: 23303344.

Liang MJ, He LC, Yang GD. Screening, analysis and in vitro vasodilatation of effective components from Ligusticum Chuanxiong. Life Sci. 2005 Nov 26;78(2):128-33. PMID: 16154159.

Weiser M, Hilz MJ, Bronfin L, et al. Assessing microcirculation in familial dysautonomia by laser Doppler flowmeter. Clin Auton Res. 1998 Feb;8(1):13-23. PMID: 9532416.

Laudenslager ML. The influence of hypothalamic temperature on some thermoregulatory effects of hypothalamic injections of norepinephrine. Pharmacol Biochem Behav. 1976 Dec;5(6):713-6. PMID: 828727.

" T+ "UN number: 2811  Class:  6.1  Packing Group:  II

Proper shipping name:  Toxic solids, organic, n.o.s. (L-(-)-Norepinephrine (+)-bitartrate salt monohydrate)

Marine pollutant:  No   Poison inhalation Hazard:  No"

LKT N5766 Norepinephrine Bitartrate Monohydrate 1 g 163.2 Endogenous hormone and neurotransmitter involved in sympathetic nervous system activity, reward, feeding, and other behaviors; α/β-adrenergic agonist. 4-[(1R)-2-Amino-1-hydroxyethyl]-1,2-benzenediol d-Bitartrate Norepinephrine d-Bitartrate; Levarterenol bitartrate 108341-18-0 ≥98% 337.28 C8H11NO3 C4H6O6 H2O C1=CC(=C(C=C1C(CN)O)O)O.C(C(C(=O)O)O)(C(=O)O)O.O Ambient Ambient Soluble in water (400 mg/mL).  Slightly soluble in ethanol (3 mg/mL). "Lavine JA, Sang Y, Wang S, et al. Attenuation of choroidal neovascularization by β(2)-adrenoreceptor antagonism. JAMA Ophthalmol. 2013 Mar;131(3):376-82. PMID: 23303344.

Liang MJ, He LC, Yang GD. Screening, analysis and in vitro vasodilatation of effective components from Ligusticum Chuanxiong. Life Sci. 2005 Nov 26;78(2):128-33. PMID: 16154159.

Weiser M, Hilz MJ, Bronfin L, et al. Assessing microcirculation in familial dysautonomia by laser Doppler flowmeter. Clin Auton Res. 1998 Feb;8(1):13-23. PMID: 9532416.

Laudenslager ML. The influence of hypothalamic temperature on some thermoregulatory effects of hypothalamic injections of norepinephrine. Pharmacol Biochem Behav. 1976 Dec;5(6):713-6. PMID: 828727.

" T+ "UN number: 2811  Class:  6.1  Packing Group:  II

Proper shipping name:  Toxic solids, organic, n.o.s. (L-(-)-Norepinephrine (+)-bitartrate salt monohydrate)

Marine pollutant:  No   Poison inhalation Hazard:  No"

LKT R0243 Raloxifene Hydrochloride 250 mg 123.8 SERM. [6-hydroxy-2-(4-hydroxyphenyl)benzo[b]thien-3-yl]-  [4-[ 2-(1-piperidinyl) ethoxy] phenyl]methanone hydrochloride Evista 82640-04-8 ≥98% 510.05 C28H27NO4S HCl C1CCN(CC1)CCOC2=CC=C(C=C2)C(=O)C3=C(SC4=C3C=CC(=C4)O)C5=CC=C(C=C5)O.Cl Ambient Ambient Very slightly soluble in water. Soluble in DMSO at 28 mg/mL. "Karki P, Webb A, Zerguine A, et al. Mechanism of raloxifene-induced upregulation of glutamate transporters in rat primary astrocytes. Glia. 2014 Aug;62(8):1270-83. PMID: 24782323.

Reimão JQ, Miguel DC, Taniwaki NN, et al. Antileishmanial activity of the estrogen receptor modulator raloxifene. PLoS Negl Trop Dis. 2014 May 8;8(5):e2842. PMID: 24810565.

Gallant MA, Brown DM, Hammond M, et al. Bone cell-independent benefits of raloxifene on the skeleton: a novel mechanism for improving bone material properties. Bone. 2014 Apr;61:191-200. PMID: 24468719.

Taurin S, Allen KM, Scandlyn MJ, et al. Raloxifene reduces triple-negative breast cancer tumor growth and decreases EGFR expression. Int J Oncol. 2013 Sep;43(3):785-92. PMID: 23842642.

Gizzo S, Saccardi C, Patrelli TS, et al. Update on raloxifene: mechanism of action, clinical efficacy, adverse effects, and contraindications. Obstet Gynecol Surv. 2013 Jun;68(6):467-81. PMID: 23942473.

" None Not dangerous goods.

LKT R0243 Raloxifene Hydrochloride 500 mg 192.4 SERM. [6-hydroxy-2-(4-hydroxyphenyl)benzo[b]thien-3-yl]-  [4-[ 2-(1-piperidinyl) ethoxy] phenyl]methanone hydrochloride Evista 82640-04-8 ≥98% 510.05 C28H27NO4S HCl C1CCN(CC1)CCOC2=CC=C(C=C2)C(=O)C3=C(SC4=C3C=CC(=C4)O)C5=CC=C(C=C5)O.Cl Ambient Ambient Very slightly soluble in water. Soluble in DMSO at 28 mg/mL. "Karki P, Webb A, Zerguine A, et al. Mechanism of raloxifene-induced upregulation of glutamate transporters in rat primary astrocytes. Glia. 2014 Aug;62(8):1270-83. PMID: 24782323.

Reimão JQ, Miguel DC, Taniwaki NN, et al. Antileishmanial activity of the estrogen receptor modulator raloxifene. PLoS Negl Trop Dis. 2014 May 8;8(5):e2842. PMID: 24810565.

Gallant MA, Brown DM, Hammond M, et al. Bone cell-independent benefits of raloxifene on the skeleton: a novel mechanism for improving bone material properties. Bone. 2014 Apr;61:191-200. PMID: 24468719.

Taurin S, Allen KM, Scandlyn MJ, et al. Raloxifene reduces triple-negative breast cancer tumor growth and decreases EGFR expression. Int J Oncol. 2013 Sep;43(3):785-92. PMID: 23842642.

Gizzo S, Saccardi C, Patrelli TS, et al. Update on raloxifene: mechanism of action, clinical efficacy, adverse effects, and contraindications. Obstet Gynecol Surv. 2013 Jun;68(6):467-81. PMID: 23942473.

" None Not dangerous goods.

LKT R0243 Raloxifene Hydrochloride 1 g 343.4 SERM. [6-hydroxy-2-(4-hydroxyphenyl)benzo[b]thien-3-yl]-  [4-[ 2-(1-piperidinyl) ethoxy] phenyl]methanone hydrochloride Evista 82640-04-8 ≥98% 510.05 C28H27NO4S HCl C1CCN(CC1)CCOC2=CC=C(C=C2)C(=O)C3=C(SC4=C3C=CC(=C4)O)C5=CC=C(C=C5)O.Cl Ambient Ambient Very slightly soluble in water. Soluble in DMSO at 28 mg/mL. "Karki P, Webb A, Zerguine A, et al. Mechanism of raloxifene-induced upregulation of glutamate transporters in rat primary astrocytes. Glia. 2014 Aug;62(8):1270-83. PMID: 24782323.

Reimão JQ, Miguel DC, Taniwaki NN, et al. Antileishmanial activity of the estrogen receptor modulator raloxifene. PLoS Negl Trop Dis. 2014 May 8;8(5):e2842. PMID: 24810565.

Gallant MA, Brown DM, Hammond M, et al. Bone cell-independent benefits of raloxifene on the skeleton: a novel mechanism for improving bone material properties. Bone. 2014 Apr;61:191-200. PMID: 24468719.

Taurin S, Allen KM, Scandlyn MJ, et al. Raloxifene reduces triple-negative breast cancer tumor growth and decreases EGFR expression. Int J Oncol. 2013 Sep;43(3):785-92. PMID: 23842642.

Gizzo S, Saccardi C, Patrelli TS, et al. Update on raloxifene: mechanism of action, clinical efficacy, adverse effects, and contraindications. Obstet Gynecol Surv. 2013 Jun;68(6):467-81. PMID: 23942473.

" None Not dangerous goods.

LKT R0212 Radicicol 1 mg 88.3 Benzoquinone ansamycin; topoisomerase VI-B, HSP90, Raf, Src family kinase inhibitor. 8-Chloro-1a,14,15,15a-tetrahydro-9,11-dihyroxy-14- methyl-6H-oxireno[e][2]benzoxacyclotetradecin- 6,12(7H)-dione Monorden; Monorderne 12772-57-5 ≥96% 364.78 C18H17ClO6 CC1CC2C(O2)C=CC=CC(=O)CC3=C(C(=CC(=C3Cl)O)O)C(=O)O1 Ambient -20°C Soluble in DMSO, methanol or ethanol. "Chalapareddy S, Bhattacharyya MK, Mishra S, et al. Radicicol Confers Mid-Schizont Arrest by Inhibiting Mitochondrial Replication in Plasmodium falciparum. Antimicrob Agents Chemother. 2014 Aug;58(8):4341-4352. PMID: 24841259.

Gadelle D, Bocs C, Graille M, et al. Inhibition of archaeal growth and DNA topoisomerase VI activities by the Hsp90 inhibitor radicicol. Nucleic Acids Res. 2005 Apr 22;33(7):2310-7. PMID: 15849317.

Sano M, Yoshida M, Fukui S, et al. Radicicol potentiates neurotrophin-mediated neurite outgrowth and survival of cultured sensory neurons from chick embryo. J Neurochem. 1999 Jun;72(6):2256-63. PMID: 10349833.

" Xn,, Xi "UN number: 2811     Class:  6.1     Packing group:  III

Proper shipping name:  Toxic solids, organic, n.o.s. (Radicicol)

Reportable Quantity (RQ):"

LKT R0212 Radicicol 5 mg 380.5 Benzoquinone ansamycin; topoisomerase VI-B, HSP90, Raf, Src family kinase inhibitor. 8-Chloro-1a,14,15,15a-tetrahydro-9,11-dihyroxy-14- methyl-6H-oxireno[e][2]benzoxacyclotetradecin- 6,12(7H)-dione Monorden; Monorderne 12772-57-5 ≥96% 364.78 C18H17ClO6 CC1CC2C(O2)C=CC=CC(=O)CC3=C(C(=CC(=C3Cl)O)O)C(=O)O1 Ambient -20°C Soluble in DMSO, methanol or ethanol. "Chalapareddy S, Bhattacharyya MK, Mishra S, et al. Radicicol Confers Mid-Schizont Arrest by Inhibiting Mitochondrial Replication in Plasmodium falciparum. Antimicrob Agents Chemother. 2014 Aug;58(8):4341-4352. PMID: 24841259.

Gadelle D, Bocs C, Graille M, et al. Inhibition of archaeal growth and DNA topoisomerase VI activities by the Hsp90 inhibitor radicicol. Nucleic Acids Res. 2005 Apr 22;33(7):2310-7. PMID: 15849317.

Sano M, Yoshida M, Fukui S, et al. Radicicol potentiates neurotrophin-mediated neurite outgrowth and survival of cultured sensory neurons from chick embryo. J Neurochem. 1999 Jun;72(6):2256-63. PMID: 10349833.

" Xn,, Xi "UN number: 2811     Class:  6.1     Packing group:  III

Proper shipping name:  Toxic solids, organic, n.o.s. (Radicicol)

Reportable Quantity (RQ):"

LKT N5767 Norethindrone 250 mg 74 Steroid hormone, contraceptive; PR agonist. 17α-17-Hydroxy-19-norpregnen-4-20-yn-3-one Menzol; Micronovum; Norlutin; Utovaln 68-22-4 ≥98% 298.42 C20H26O2 CC12CCC3C(C1CCC2(C#C)O)CCC4=CC(=O)CCC34 Ambient Ambient Insoluble in water.  Soluble in acetone, ethanol, chloroform and dioxane. "Shoupe D. HRT dosing regimens: continuous versus cyclic-pros and cons. Int J Fertil Womens Med. 2001 Jan-Feb;46(1):7-15. PMID: 11294619.

Saha A, Roy K, De K, et al. Effects of oral contraceptive norethindrone on blood-lipid and lipid peroxidation parameters. Acta Pol Pharm. 2000 Nov-Dec;57(6):441-7. PMID: 11243250.

Couzinet B, Young J, Brailly S, et al. The antigonadotropic activity of progestins (19-nortestosterone and 19-norprogesterone derivatives) is not mediated through the androgen receptor. J Clin Endocrinol Metab. 1996 Dec;81(12):4218-23. PMID: 8954018.

" Carc., Xn, Xi Not dangerous goods.

LKT N5767 Norethindrone 1 g 120.1 Steroid hormone, contraceptive; PR agonist. 17α-17-Hydroxy-19-norpregnen-4-20-yn-3-one Menzol; Micronovum; Norlutin; Utovaln 68-22-4 ≥98% 298.42 C20H26O2 CC12CCC3C(C1CCC2(C#C)O)CCC4=CC(=O)CCC34 Ambient Ambient Insoluble in water.  Soluble in acetone, ethanol, chloroform and dioxane. "Shoupe D. HRT dosing regimens: continuous versus cyclic-pros and cons. Int J Fertil Womens Med. 2001 Jan-Feb;46(1):7-15. PMID: 11294619.

Saha A, Roy K, De K, et al. Effects of oral contraceptive norethindrone on blood-lipid and lipid peroxidation parameters. Acta Pol Pharm. 2000 Nov-Dec;57(6):441-7. PMID: 11243250.

Couzinet B, Young J, Brailly S, et al. The antigonadotropic activity of progestins (19-nortestosterone and 19-norprogesterone derivatives) is not mediated through the androgen receptor. J Clin Endocrinol Metab. 1996 Dec;81(12):4218-23. PMID: 8954018.

" Carc., Xn, Xi Not dangerous goods.

LKT N5767 Norethindrone 5 g 462.1 Steroid hormone, contraceptive; PR agonist. 17α-17-Hydroxy-19-norpregnen-4-20-yn-3-one Menzol; Micronovum; Norlutin; Utovaln 68-22-4 ≥98% 298.42 C20H26O2 CC12CCC3C(C1CCC2(C#C)O)CCC4=CC(=O)CCC34 Ambient Ambient Insoluble in water.  Soluble in acetone, ethanol, chloroform and dioxane. "Shoupe D. HRT dosing regimens: continuous versus cyclic-pros and cons. Int J Fertil Womens Med. 2001 Jan-Feb;46(1):7-15. PMID: 11294619.

Saha A, Roy K, De K, et al. Effects of oral contraceptive norethindrone on blood-lipid and lipid peroxidation parameters. Acta Pol Pharm. 2000 Nov-Dec;57(6):441-7. PMID: 11243250.

Couzinet B, Young J, Brailly S, et al. The antigonadotropic activity of progestins (19-nortestosterone and 19-norprogesterone derivatives) is not mediated through the androgen receptor. J Clin Endocrinol Metab. 1996 Dec;81(12):4218-23. PMID: 8954018.

" Carc., Xn, Xi Not dangerous goods.

LKT R0109 Racecadotril 500 mg 163.2 Enkephalinase inhibitor. N-[2-[(Acetylthio)methyl]-1-oxo-3-phenylpropyl]- glycine phenylmethyl ester Acetorphan; Hidrasec; Tiorfan 81110-73-8 ≥98% 385.48 C21H23NO4S CC(=O)SCC(CC1=CC=CC=C1)C(=O)NCC(=O)OCC2=CC=CC=C2 Ambient Ambient Soluble in methanol, ethanol (75 mg/ml), DMSO (45 mg/ml), or chloroform. "Matheson AJ, Noble S. Racecadotril. Drugs. 2000 Apr;59(4):829-35; discussion 836-7. PMID: 10804038.

Lecomte JM. An overview of clinical studies with racecadotril in adults. Int J Antimicrob Agents. 2000 Feb;14(1):81-7. PMID: 10717506.

" Xn, N Not dangerous goods.

LKT R0109 Racecadotril 1 g 251.5 Enkephalinase inhibitor. N-[2-[(Acetylthio)methyl]-1-oxo-3-phenylpropyl]- glycine phenylmethyl ester Acetorphan; Hidrasec; Tiorfan 81110-73-8 ≥98% 385.48 C21H23NO4S CC(=O)SCC(CC1=CC=CC=C1)C(=O)NCC(=O)OCC2=CC=CC=C2 Ambient Ambient Soluble in methanol, ethanol (75 mg/ml), DMSO (45 mg/ml), or chloroform. "Matheson AJ, Noble S. Racecadotril. Drugs. 2000 Apr;59(4):829-35; discussion 836-7. PMID: 10804038.

Lecomte JM. An overview of clinical studies with racecadotril in adults. Int J Antimicrob Agents. 2000 Feb;14(1):81-7. PMID: 10717506.

" Xn, N Not dangerous goods.

LKT R0109 Racecadotril 100 mg 47.6 Enkephalinase inhibitor. N-[2-[(Acetylthio)methyl]-1-oxo-3-phenylpropyl]- glycine phenylmethyl ester Acetorphan; Hidrasec; Tiorfan 81110-73-8 ≥98% 385.48 C21H23NO4S CC(=O)SCC(CC1=CC=CC=C1)C(=O)NCC(=O)OCC2=CC=CC=C2 Ambient Ambient Soluble in methanol, ethanol (75 mg/ml), DMSO (45 mg/ml), or chloroform. "Matheson AJ, Noble S. Racecadotril. Drugs. 2000 Apr;59(4):829-35; discussion 836-7. PMID: 10804038.

Lecomte JM. An overview of clinical studies with racecadotril in adults. Int J Antimicrob Agents. 2000 Feb;14(1):81-7. PMID: 10717506.

" Xn, N Not dangerous goods.

LKT R0105 Rabeprazole Sodium 10 mg 67.9 H+/K+ ATPase and Scpc phosphatase inhibitor. 2[[[4-(3-Methoxypropoxy)-3-methyl-2-pyridinyl]methyl]sulfinyl]-1H-benzimidazole Pariprazole 117976-90-6 ≥98% 381.42 C18H20N3O3S Na CC1=C(C=CN=C1CS(=O)C2=NC3=CC=CC=C3[N-]2)OCCCOC.[Na+] Store at -20°C Ambient -20°C Insoluble in water.  Soluble in DMSO. "Ward RM, Kearns GL. Proton pump inhibitors in pediatrics : mechanism of action, pharmacokinetics, pharmacogenetics, and pharmacodynamics. Paediatr Drugs. 2013 Apr;15(2):119-31. PMID: 23512128.

Zhang M, Cho EJ, Burstein G, et al. Selective inactivation of a human neuronal silencing phosphatase by a small molecule inhibitor. ACS Chem Biol. 2011 May 20;6(5):511-9. PMID: 21348431.

Sanaka M, Anjiki H, Yamamoto T, et al. Rabeprazole delays gastric emptying of a nutrient liquid. J Gastroenterol Hepatol. 2007 Nov;22(11):1806-9. PMID: 17914954.

" Not dangerous goods.

LKT N5768 Norfloxacin 10 g 105.2 Fluoroquinolone; topoisomerase IV and bacterial DNA gyrase inhibitor. "1-Ethyl-6-fluoro-1,4-dihydro-4-oxo-7-(1-piperazinyl)-3-quinolinecarboxylic acid

" Baccidal; Sebercim 70458-96-7 ≥98% 319.33 C16H18FN3O3 CCN1C=C(C(=O)C2=CC(=C(C=C21)N3CCNCC3)F)C(=O)O Ambient Ambient Soly at 25oC (mg/ml): water 0.28; methanol 0.98; ethanol 1.9. "Gouvea LR, Garcia LS, Lachter DR, et al.  Atypical fluoroquinolone gold(III) chelates as potential anticancer agents: relevance of DNA and protein interactions for their mechanism of action. Eur J Med Chem. 2012 Sep;55:67-73. PMID: 22835721.

Gómez-Hurtado I, Zapater P, Bellot P, et al. Interleukin-10-mediated heme oxygenase 1-induced underlying mechanism in inflammatory down-regulation by norfloxacin in cirrhosis. Hepatology. 2011 Mar;53(3):935-44. PMID: 21374664.

Padeĭskaia EN. Norfloxacin: more than 20 years of clinical use, the results and place among fluoroquinolones in modern chemotherapy for infections. Antibiot Khimioter. 2003;48(9):28-36. PMID: 15002177.

Drlica K, Zhao X. DNA gyrase, topoisomerase IV, and the 4-quinolones. Microbiol Mol Biol Rev. 1997 Sep;61(3):377-92. PMID: 9293187.

Ho YB, Zakaria MP, Latif PA, Saari N. Occurrence of veterinary antibiotics and progesterone in broiler manure and agricultural soil in Malaysia. Sci Total Environ. 2014 Aug 1;488-489:261-267. PMID: 24836135.

" None Not dangerous goods.

LKT R0105 Rabeprazole Sodium 25 mg 136 H+/K+ ATPase and Scpc phosphatase inhibitor. 2[[[4-(3-Methoxypropoxy)-3-methyl-2-pyridinyl]methyl]sulfinyl]-1H-benzimidazole Pariprazole 117976-90-6 ≥98% 381.42 C18H20N3O3S Na CC1=C(C=CN=C1CS(=O)C2=NC3=CC=CC=C3[N-]2)OCCCOC.[Na+] Store at -20°C Ambient -20°C Insoluble in water.  Soluble in DMSO. "Ward RM, Kearns GL. Proton pump inhibitors in pediatrics : mechanism of action, pharmacokinetics, pharmacogenetics, and pharmacodynamics. Paediatr Drugs. 2013 Apr;15(2):119-31. PMID: 23512128.

Zhang M, Cho EJ, Burstein G, et al. Selective inactivation of a human neuronal silencing phosphatase by a small molecule inhibitor. ACS Chem Biol. 2011 May 20;6(5):511-9. PMID: 21348431.

Sanaka M, Anjiki H, Yamamoto T, et al. Rabeprazole delays gastric emptying of a nutrient liquid. J Gastroenterol Hepatol. 2007 Nov;22(11):1806-9. PMID: 17914954.

" Not dangerous goods.

LKT N5768 Norfloxacin 50 g 374.5 Fluoroquinolone; topoisomerase IV and bacterial DNA gyrase inhibitor. "1-Ethyl-6-fluoro-1,4-dihydro-4-oxo-7-(1-piperazinyl)-3-quinolinecarboxylic acid

" Baccidal; Sebercim 70458-96-7 ≥98% 319.33 C16H18FN3O3 CCN1C=C(C(=O)C2=CC(=C(C=C21)N3CCNCC3)F)C(=O)O Ambient Ambient Soly at 25oC (mg/ml): water 0.28; methanol 0.98; ethanol 1.9. "Gouvea LR, Garcia LS, Lachter DR, et al.  Atypical fluoroquinolone gold(III) chelates as potential anticancer agents: relevance of DNA and protein interactions for their mechanism of action. Eur J Med Chem. 2012 Sep;55:67-73. PMID: 22835721.

Gómez-Hurtado I, Zapater P, Bellot P, et al. Interleukin-10-mediated heme oxygenase 1-induced underlying mechanism in inflammatory down-regulation by norfloxacin in cirrhosis. Hepatology. 2011 Mar;53(3):935-44. PMID: 21374664.

Padeĭskaia EN. Norfloxacin: more than 20 years of clinical use, the results and place among fluoroquinolones in modern chemotherapy for infections. Antibiot Khimioter. 2003;48(9):28-36. PMID: 15002177.

Drlica K, Zhao X. DNA gyrase, topoisomerase IV, and the 4-quinolones. Microbiol Mol Biol Rev. 1997 Sep;61(3):377-92. PMID: 9293187.

Ho YB, Zakaria MP, Latif PA, Saari N. Occurrence of veterinary antibiotics and progesterone in broiler manure and agricultural soil in Malaysia. Sci Total Environ. 2014 Aug 1;488-489:261-267. PMID: 24836135.

" None Not dangerous goods.

LKT R0105 Rabeprazole Sodium 100 mg 434.9 H+/K+ ATPase and Scpc phosphatase inhibitor. 2[[[4-(3-Methoxypropoxy)-3-methyl-2-pyridinyl]methyl]sulfinyl]-1H-benzimidazole Pariprazole 117976-90-6 ≥98% 381.42 C18H20N3O3S Na CC1=C(C=CN=C1CS(=O)C2=NC3=CC=CC=C3[N-]2)OCCCOC.[Na+] Store at -20°C Ambient -20°C Insoluble in water.  Soluble in DMSO. "Ward RM, Kearns GL. Proton pump inhibitors in pediatrics : mechanism of action, pharmacokinetics, pharmacogenetics, and pharmacodynamics. Paediatr Drugs. 2013 Apr;15(2):119-31. PMID: 23512128.

Zhang M, Cho EJ, Burstein G, et al. Selective inactivation of a human neuronal silencing phosphatase by a small molecule inhibitor. ACS Chem Biol. 2011 May 20;6(5):511-9. PMID: 21348431.

Sanaka M, Anjiki H, Yamamoto T, et al. Rabeprazole delays gastric emptying of a nutrient liquid. J Gastroenterol Hepatol. 2007 Nov;22(11):1806-9. PMID: 17914954.

" Not dangerous goods.

LKT N5769 Norfloxacin Nicotinate 10 g 95.1 Fluoroquinolone; topoisomerase IV and bacterial DNA gyrase inhibitor. 118803-81-9 ≥98% 442.44 C16H18FN3O3C6H5NO2 CCN1C=C(C(=O)C2=CC(=C(C=C21)N3CCNCC3)F)C(=O)O.C1=CC(=CN=C1)C(=O)O Ambient Ambient Soluble in water. "Gouvea LR, Garcia LS, Lachter DR, et al.  Atypical fluoroquinolone gold(III) chelates as potential anticancer agents: relevance of DNA and protein interactions for their mechanism of action. Eur J Med Chem. 2012 Sep;55:67-73. PMID: 22835721.

Gómez-Hurtado I, Zapater P, Bellot P, et al. Interleukin-10-mediated heme oxygenase 1-induced underlying mechanism in inflammatory down-regulation by norfloxacin in cirrhosis. Hepatology. 2011 Mar;53(3):935-44. PMID: 21374664.

Padeĭskaia EN. Norfloxacin: more than 20 years of clinical use, the results and place among fluoroquinolones in modern chemotherapy for infections. Antibiot Khimioter. 2003;48(9):28-36. PMID: 15002177.

Drlica K, Zhao X. DNA gyrase, topoisomerase IV, and the 4-quinolones. Microbiol Mol Biol Rev. 1997 Sep;61(3):377-92. PMID: 9293187.

" Not dangerous goods.

LKT N5769 Norfloxacin Nicotinate 50 g 305.9 Fluoroquinolone; topoisomerase IV and bacterial DNA gyrase inhibitor. 118803-81-9 ≥98% 442.44 C16H18FN3O3C6H5NO2 CCN1C=C(C(=O)C2=CC(=C(C=C21)N3CCNCC3)F)C(=O)O.C1=CC(=CN=C1)C(=O)O Ambient Ambient Soluble in water. "Gouvea LR, Garcia LS, Lachter DR, et al.  Atypical fluoroquinolone gold(III) chelates as potential anticancer agents: relevance of DNA and protein interactions for their mechanism of action. Eur J Med Chem. 2012 Sep;55:67-73. PMID: 22835721.

Gómez-Hurtado I, Zapater P, Bellot P, et al. Interleukin-10-mediated heme oxygenase 1-induced underlying mechanism in inflammatory down-regulation by norfloxacin in cirrhosis. Hepatology. 2011 Mar;53(3):935-44. PMID: 21374664.

Padeĭskaia EN. Norfloxacin: more than 20 years of clinical use, the results and place among fluoroquinolones in modern chemotherapy for infections. Antibiot Khimioter. 2003;48(9):28-36. PMID: 15002177.

Drlica K, Zhao X. DNA gyrase, topoisomerase IV, and the 4-quinolones. Microbiol Mol Biol Rev. 1997 Sep;61(3):377-92. PMID: 9293187.

" Not dangerous goods.

LKT N5778 Notoginsenoside R1 5 mg 163.2 Triterpene saponin found in species of Panax. 80418-24-2 ≥98% 933.13 C47H80O18 CC(=CCCC(C)(C1CCC2(C1C(CC3C2(CC(C4C3(CCC(C4(C)C)O)C)OC5C(C(C(C(O5)CO)O)O)OC6C(C(C(CO6)O)O)O)C)O)C)OC7C(C(C(C(O7)CO)O)O)O)C Ambient 4°C Soluble in DMSO. "Ma B, Meng X, Wang J, et al. Notoginsenoside R1 attenuates amyloid-β-induced damage in neurons by inhibiting reactive oxygen species and modulating MAPK activation. Int Immunopharmacol. 2014 Jun 24;22(1):151-159. PMID: 24975829.

Jia C, Xiong M, Wang P, et al. Notoginsenoside R1 Attenuates Atherosclerotic Lesions in ApoE Deficient Mouse Model. PLoS One. 2014 Jun 16;9(6):e99849. PMID: 24933211.

Sun HX, Chen Y, Ye Y. Ginsenoside Re and notoginsenoside R1: Immunologic adjuvants with low haemolytic effect. Chem Biodivers. 2006 Jul;3(7):718-26. PMID: 17193304.

" None Not dangerous goods.

LKT N5778 Notoginsenoside R1 10 mg 271.7 Triterpene saponin found in species of Panax. 80418-24-2 ≥98% 933.13 C47H80O18 CC(=CCCC(C)(C1CCC2(C1C(CC3C2(CC(C4C3(CCC(C4(C)C)O)C)OC5C(C(C(C(O5)CO)O)O)OC6C(C(C(CO6)O)O)O)C)O)C)OC7C(C(C(C(O7)CO)O)O)O)C Ambient 4°C Soluble in DMSO. "Ma B, Meng X, Wang J, et al. Notoginsenoside R1 attenuates amyloid-β-induced damage in neurons by inhibiting reactive oxygen species and modulating MAPK activation. Int Immunopharmacol. 2014 Jun 24;22(1):151-159. PMID: 24975829.

Jia C, Xiong M, Wang P, et al. Notoginsenoside R1 Attenuates Atherosclerotic Lesions in ApoE Deficient Mouse Model. PLoS One. 2014 Jun 16;9(6):e99849. PMID: 24933211.

Sun HX, Chen Y, Ye Y. Ginsenoside Re and notoginsenoside R1: Immunologic adjuvants with low haemolytic effect. Chem Biodivers. 2006 Jul;3(7):718-26. PMID: 17193304.

" None Not dangerous goods.

LKT N5778 Notoginsenoside R1 25 mg 543.6 Triterpene saponin found in species of Panax. 80418-24-2 ≥98% 933.13 C47H80O18 CC(=CCCC(C)(C1CCC2(C1C(CC3C2(CC(C4C3(CCC(C4(C)C)O)C)OC5C(C(C(C(O5)CO)O)O)OC6C(C(C(CO6)O)O)O)C)O)C)OC7C(C(C(C(O7)CO)O)O)O)C Ambient 4°C Soluble in DMSO. "Ma B, Meng X, Wang J, et al. Notoginsenoside R1 attenuates amyloid-β-induced damage in neurons by inhibiting reactive oxygen species and modulating MAPK activation. Int Immunopharmacol. 2014 Jun 24;22(1):151-159. PMID: 24975829.

Jia C, Xiong M, Wang P, et al. Notoginsenoside R1 Attenuates Atherosclerotic Lesions in ApoE Deficient Mouse Model. PLoS One. 2014 Jun 16;9(6):e99849. PMID: 24933211.

Sun HX, Chen Y, Ye Y. Ginsenoside Re and notoginsenoside R1: Immunologic adjuvants with low haemolytic effect. Chem Biodivers. 2006 Jul;3(7):718-26. PMID: 17193304.

" None Not dangerous goods.

LKT N6020 Neuropeptide F 1 mg 192.3 Neuropeptide Y analog found in insects, involved in circadian rhythms. NPF ≥95% 768.79 C51H80N15O19P Ambient -20°C "Shang Y, Donelson NC, Vecsey CG, et al. Short neuropeptide F is a sleep-promoting inhibitory modulator. Neuron. 2013 Oct 2;80(1):171-83. PMID: 24094110.

Chen W, Shi W, Li L, et al. Regulation of sleep by the short neuropeptide F (sNPF) in Drosophila melanogaster. Insect Biochem Mol Biol. 2013 Sep;43(9):809-19. PMID: 23796436.

Van Wielendaele P, Wynant N, Dillen S, et al. In vivo effect of Neuropeptide F on ecdysteroidogenesis in adult female desert locusts (Schistocerca gregaria). J Insect Physiol. 2013 Jun;59(6):624-30. PMID: 23524065.

Van Wielendaele P, Wynant N, Dillen S, et al. Neuropeptide F regulates male reproductive processes in the desert locust, Schistocerca gregaria. Insect Biochem Mol Biol. 2013 Mar;43(3):252-9. PMID: 23295785.

Leung PS, Shaw C, Johnston CF, et al. Immunocytochemical distribution of neuropeptide F (NPF) in the gastropod mollusc, Helix aspersa, and in several other invertebrates. Cell Tissue Res. 1994 Feb;275(2):383-93. PMID: 8111844.

"

LKT N6020 Neuropeptide F 2 mg 324 Neuropeptide Y analog found in insects, involved in circadian rhythms. NPF ≥95% 768.79 C51H80N15O19P Ambient -20°C "Shang Y, Donelson NC, Vecsey CG, et al. Short neuropeptide F is a sleep-promoting inhibitory modulator. Neuron. 2013 Oct 2;80(1):171-83. PMID: 24094110.

Chen W, Shi W, Li L, et al. Regulation of sleep by the short neuropeptide F (sNPF) in Drosophila melanogaster. Insect Biochem Mol Biol. 2013 Sep;43(9):809-19. PMID: 23796436.

Van Wielendaele P, Wynant N, Dillen S, et al. In vivo effect of Neuropeptide F on ecdysteroidogenesis in adult female desert locusts (Schistocerca gregaria). J Insect Physiol. 2013 Jun;59(6):624-30. PMID: 23524065.

Van Wielendaele P, Wynant N, Dillen S, et al. Neuropeptide F regulates male reproductive processes in the desert locust, Schistocerca gregaria. Insect Biochem Mol Biol. 2013 Mar;43(3):252-9. PMID: 23295785.

Leung PS, Shaw C, Johnston CF, et al. Immunocytochemical distribution of neuropeptide F (NPF) in the gastropod mollusc, Helix aspersa, and in several other invertebrates. Cell Tissue Res. 1994 Feb;275(2):383-93. PMID: 8111844.

"

LKT N6020 Neuropeptide F 5 mg 576.1 Neuropeptide Y analog found in insects, involved in circadian rhythms. NPF ≥95% 768.79 C51H80N15O19P Ambient -20°C "Shang Y, Donelson NC, Vecsey CG, et al. Short neuropeptide F is a sleep-promoting inhibitory modulator. Neuron. 2013 Oct 2;80(1):171-83. PMID: 24094110.

Chen W, Shi W, Li L, et al. Regulation of sleep by the short neuropeptide F (sNPF) in Drosophila melanogaster. Insect Biochem Mol Biol. 2013 Sep;43(9):809-19. PMID: 23796436.

Van Wielendaele P, Wynant N, Dillen S, et al. In vivo effect of Neuropeptide F on ecdysteroidogenesis in adult female desert locusts (Schistocerca gregaria). J Insect Physiol. 2013 Jun;59(6):624-30. PMID: 23524065.

Van Wielendaele P, Wynant N, Dillen S, et al. Neuropeptide F regulates male reproductive processes in the desert locust, Schistocerca gregaria. Insect Biochem Mol Biol. 2013 Mar;43(3):252-9. PMID: 23295785.

Leung PS, Shaw C, Johnston CF, et al. Immunocytochemical distribution of neuropeptide F (NPF) in the gastropod mollusc, Helix aspersa, and in several other invertebrates. Cell Tissue Res. 1994 Feb;275(2):383-93. PMID: 8111844.

"

LKT N6076 N(p-Tosyl)-GPR-pNA 100 mg 1005 Thrombin substrate used to measure thrombin activity. ≥95% 602 C26H34N8O7S Ambient -20°C Thiagarajan P, Dannenbring R, Matsuura K, et al. Monoclonal antibody light chain with prothrombinase activity. Biochemistry. 2000 May 30;39(21):6459-65. PMID: 10828960.

LKT N7604 Naltriben 0.5 mg 132 δ2OR antagonist. NTB ≥95% 1060.29 C50H65N11O11S2 Ambient -20°C "Sugiyama A, Nagase H, Oka JI, et al. DOR2-selective but not DOR1-selective antagonist abolishes anxiolytic-like effects of the δ opioid receptor agonist KNT-127. Neuropharmacology. 2013 Dec 12;79C:314-320. PMID: 24333676.

Billa SK, Xia Y, Morón JA. Disruption of morphine-conditioned place preference by a delta2-opioid receptor antagonist: study of mu-opioid and delta-opioid receptor expression at the synapse. Eur J Neurosci. 2010 Aug;32(4):625-31. PMID: 20626460.

Tseng LF, Collins KA, Portoghese PS. Spinal delta 2 but not delta 1 opioid receptors are involved in intracerebroventricular beta-endorphin-induced antinociception in the mouse. Life Sci. 1993;52(19):PL211-5. PMID: 8387138.

"

LKT N7604 Naltriben 1 mg 222 δ2OR antagonist. NTB ≥95% 1060.29 C50H65N11O11S2 Ambient -20°C "Sugiyama A, Nagase H, Oka JI, et al. DOR2-selective but not DOR1-selective antagonist abolishes anxiolytic-like effects of the δ opioid receptor agonist KNT-127. Neuropharmacology. 2013 Dec 12;79C:314-320. PMID: 24333676.

Billa SK, Xia Y, Morón JA. Disruption of morphine-conditioned place preference by a delta2-opioid receptor antagonist: study of mu-opioid and delta-opioid receptor expression at the synapse. Eur J Neurosci. 2010 Aug;32(4):625-31. PMID: 20626460.

Tseng LF, Collins KA, Portoghese PS. Spinal delta 2 but not delta 1 opioid receptors are involved in intracerebroventricular beta-endorphin-induced antinociception in the mouse. Life Sci. 1993;52(19):PL211-5. PMID: 8387138.

"

LKT N7604 Naltriben 2.5 mg 396.1 δ2OR antagonist. NTB ≥95% 1060.29 C50H65N11O11S2 Ambient -20°C "Sugiyama A, Nagase H, Oka JI, et al. DOR2-selective but not DOR1-selective antagonist abolishes anxiolytic-like effects of the δ opioid receptor agonist KNT-127. Neuropharmacology. 2013 Dec 12;79C:314-320. PMID: 24333676.

Billa SK, Xia Y, Morón JA. Disruption of morphine-conditioned place preference by a delta2-opioid receptor antagonist: study of mu-opioid and delta-opioid receptor expression at the synapse. Eur J Neurosci. 2010 Aug;32(4):625-31. PMID: 20626460.

Tseng LF, Collins KA, Portoghese PS. Spinal delta 2 but not delta 1 opioid receptors are involved in intracerebroventricular beta-endorphin-induced antinociception in the mouse. Life Sci. 1993;52(19):PL211-5. PMID: 8387138.

"

LKT N9874 Nystatin 500 KU 23.6 Polyene macrolide, induces pore formation in fungal membranes. Fungicidin; Candex; Mycostatin; Nystan; O-V Statin 1400-61-9 ≥98% 926.09 C47H75NO17 CC1C=CC=CCCC=CC=CC=CC=CC(CC2C(C(CC(O2)(CC(C(CCC(CC(CC(CC(=O)OC(C(C1O)C)C)O)O)O)O)O)O)O)C(=O)O)OC3C(C(C(C(O3)C)O)N)O Protect from light. Store under nitrogen. Ambient 4°C Soluble in methanol, ethanol and water. "Serhan G, Stack CM, Perrone GG, et al. The polyene antifungals, amphotericin B and nystatin, cause cell death in Saccharomyces cerevisiae by a distinct mechanism to amphibian-derived antimicrobial peptides. Ann Clin Microbiol Antimicrob. 2014 May 12;13:18. PMID: 24884795.

Fjaervik E, Zotchev SB. Biosynthesis of the polyene macrolide antibiotic nystatin in Streptomyces noursei. Appl Microbiol Biotechnol. 2005 Jun;67(4):436-43. PMID: 15700127.

Hammond SM. Biological activity of polyene antibiotics. Prog Med Chem. 1977;14:105-79. PMID: 345355.

" None Not dangerous goods.

LKT N9874 Nystatin 1 MU 27.6 Polyene macrolide, induces pore formation in fungal membranes. Fungicidin; Candex; Mycostatin; Nystan; O-V Statin 1400-61-9 ≥98% 926.09 C47H75NO17 CC1C=CC=CCCC=CC=CC=CC=CC(CC2C(C(CC(O2)(CC(C(CCC(CC(CC(CC(=O)OC(C(C1O)C)C)O)O)O)O)O)O)O)C(=O)O)OC3C(C(C(C(O3)C)O)N)O Protect from light. Store under nitrogen. Ambient 4°C Soluble in methanol, ethanol and water. "Serhan G, Stack CM, Perrone GG, et al. The polyene antifungals, amphotericin B and nystatin, cause cell death in Saccharomyces cerevisiae by a distinct mechanism to amphibian-derived antimicrobial peptides. Ann Clin Microbiol Antimicrob. 2014 May 12;13:18. PMID: 24884795.

Fjaervik E, Zotchev SB. Biosynthesis of the polyene macrolide antibiotic nystatin in Streptomyces noursei. Appl Microbiol Biotechnol. 2005 Jun;67(4):436-43. PMID: 15700127.

Hammond SM. Biological activity of polyene antibiotics. Prog Med Chem. 1977;14:105-79. PMID: 345355.

" None Not dangerous goods.

LKT N9874 Nystatin 5 MU 68.8 Polyene macrolide, induces pore formation in fungal membranes. Fungicidin; Candex; Mycostatin; Nystan; O-V Statin 1400-61-9 ≥98% 926.09 C47H75NO17 CC1C=CC=CCCC=CC=CC=CC=CC(CC2C(C(CC(O2)(CC(C(CCC(CC(CC(CC(=O)OC(C(C1O)C)C)O)O)O)O)O)O)O)C(=O)O)OC3C(C(C(C(O3)C)O)N)O Protect from light. Store under nitrogen. Ambient 4°C Soluble in methanol, ethanol and water. "Serhan G, Stack CM, Perrone GG, et al. The polyene antifungals, amphotericin B and nystatin, cause cell death in Saccharomyces cerevisiae by a distinct mechanism to amphibian-derived antimicrobial peptides. Ann Clin Microbiol Antimicrob. 2014 May 12;13:18. PMID: 24884795.

Fjaervik E, Zotchev SB. Biosynthesis of the polyene macrolide antibiotic nystatin in Streptomyces noursei. Appl Microbiol Biotechnol. 2005 Jun;67(4):436-43. PMID: 15700127.

Hammond SM. Biological activity of polyene antibiotics. Prog Med Chem. 1977;14:105-79. PMID: 345355.

" None Not dangerous goods.

LKT NA100 NSAIDs 1 kit 148.2 Dry Ice -80°C

LKT NA101 NSAIDs 1 kit 165.1 Dry Ice -80°C

LKT NA102 NSAIDs 1 kit 165.1 Dry Ice -80°C

LKT NA103 NSAIDs 1 kit 165.1 Dry Ice -80°C

LKT NP100 Natural Products 1 kit 171.3 Dry Ice -80°C

LKT NP101 Natural Products 1 kit 159 Dry Ice -80°C

LKT NP102 Natural Products 1 kit 125.6 Dry Ice -80°C

LKT NP103 Natural Products 1 kit 136.2 Dry Ice -80°C