LKT Labs O4531 Oligomycin Macrolide

LKT Labs 是一家专注于防癌抗癌特殊化学品研究和开发的公司。主要提供：癌症药物、药物发现试剂盒、天然产物、广泛的生命科学研究试剂、定制合成。
美国LKT Labs 是1988年在美国成立的，为全球提供先端的药物研发试剂、试剂盒、委托合成，并为药物生产企业提供原料，最近几年在农药、水产养殖业有很大程度的开发。在LKT Labs 可以找到在其他地方找不到的产品。

LKT Labs O4531 Oligomycin Macrolide

LKT Labs O4531 Oligomycin Macrolide

LKT NP104 Natural Products 1 kit 272.6 Dry Ice -80°C

LKT NP105 Natural Products 1 kit 181.4 Dry Ice -80°C

LKT NP106 Natural Products 1 kit 193.1 Dry Ice -80°C

LKT NP107 Natural Products 1 kit 453.9 Dry Ice -80°C

LKT NP108 Natural Products 1 kit 412.5 Dry Ice -80°C

LKT NP109 Natural Products 1 kit 288.8 Dry Ice -80°C

LKT NP110 Natural Products 1 kit 206.3 Dry Ice -80°C

LKT NP112 Natural Products 1 kit 258 Dry Ice -80°C

LKT NP113 Natural Products 1 kit 247.6 Dry Ice -80°C

LKT NP114 Natural Products 1 kit 216.3 Dry Ice -80°C

LKT NP115 Natural Products 1 kit 268.2 Dry Ice -80°C

LKT NP116 Natural Products 1 kit 443.5 Dry Ice -80°C

LKT NP117 Natural Products 1 kit 216.6 Dry Ice -80°C

LKT NP118 Natural Products 1 kit 299 Dry Ice -80°C

LKT NP119 Natural Products 1 kit 557 Dry Ice -80°C

LKT NP120 Natural Products 1 kit 268.2 Dry Ice -80°C

LKT NP121 Natural Products 1 kit 607.3 Dry Ice -80°C

LKT NP122 Natural Products 1 kit 391.9 Dry Ice -80°C

LKT NP123 Natural Products 1 kit 783.7 Dry Ice -80°C

LKT P0001 P1 Peptide 0.5 mg 83.9 Octapeptide, prevents EGFR-PLCγ association. ≥95% 894 C39H63N11O13 Ambient -20°C Hidaka M, Homma Y, Takenawa T. Highly conserved eight amino acid sequence in SH2 is important for recognition of phosphotyrosine site. Biochem Biophys Res Commun. 1991 Nov 14;180(3):1490-7. PMID: 1719984.

LKT P0001 P1 Peptide 1 mg 245.9 Octapeptide, prevents EGFR-PLCγ association. ≥95% 894 C39H63N11O13 Ambient -20°C Hidaka M, Homma Y, Takenawa T. Highly conserved eight amino acid sequence in SH2 is important for recognition of phosphotyrosine site. Biochem Biophys Res Commun. 1991 Nov 14;180(3):1490-7. PMID: 1719984.

LKT P0001 P1 Peptide 2.5 mg 432 Octapeptide, prevents EGFR-PLCγ association. ≥95% 894 C39H63N11O13 Ambient -20°C Hidaka M, Homma Y, Takenawa T. Highly conserved eight amino acid sequence in SH2 is important for recognition of phosphotyrosine site. Biochem Biophys Res Commun. 1991 Nov 14;180(3):1490-7. PMID: 1719984.

LKT P9869 Pyridoxine Hydrochloride 25 g 37.5 Vitamin B6 derivative, antioxidant. 58-56-0 ≥98% 205.64 C8H11NO3HCl CC1=NC=C(C(=C1O)CO)CO.Cl Ambient Ambient Soluble in water (200 mg/mL), ethanol (8.5 mg/mL). "Xie L, Liu Z, Lu H, et al. Pyridoxine inhibits endothelial NOS uncoupling induced by oxidized low-density lipoprotein via the PKCα signaling pathway in human umbilical vein endothelial cells. Br J Pharmacol. 2012 Feb;165(3):754-64. PMID: 21797845.

Nakari M, Kanouchi H, Oka T. High dose of pyridoxine induces IGFBP-3 mRNA expression in MCF-7 cells and its induction is inhibited by the p53-specific inhibitor pifithrin-α. J Nutr Sci Vitaminol (Tokyo). 2011;57(4):280-4. PMID: 22041910.

Yang TT, Wang SJ. Pyridoxine inhibits depolarization-evoked glutamate release in nerve terminals from rat cerebral cortex: a possible neuroprotective mechanism? J Pharmacol Exp Ther. 2009 Oct;331(1):244-54. PMID: 19628631.

Wu Y, Liu Y, Han Y, et al. Pyridoxine increases nitric oxide biosynthesis in human platelets. Int J Vitam Nutr Res. 2009 Mar;79(2):95-103. PMID: 20108211.

Jain SK, Lim G. Pyridoxine and pyridoxamine inhibits superoxide radicals and prevents lipid peroxidation, protein glycosylation, and (Na+ + K+)-ATPase activity reduction in high glucose-treated human erythrocytes. Free Radic Biol Med. 2001 Feb 1;30(3):232-7. PMID: 11165869.

Ross JB, Moss MA. Relief of the photosensitivity of erythropoietic protoporphyria by pyridoxine. J Am Acad Dermatol. 1990 Feb;22(2 Pt 2):340-2. PMID: 2303590.

" None Not dangerous goods.

LKT P0005 Pituitary Adenylate Cyclase-activating Polypeptide (1-27), human, sheep, rat 0.5 mg 276.2 Endogenous peptide, involved in paracrine and autocrine cell signaling; PAC1 and VPAC1/2 agonist. PACAP (1-27) 127317-03-7 ≥95% 3147.68 C142H224N40O39S CCC(C)C(C(=O)NC(CC1=CC=CC=C1)C(=O)NC(C(C)O)C(=O)NC(CC(=O)O)C(=O)NC(CO)C(=O)NC(CC2=CC=C(C=C2)O)C(=O)NC(CO)C(=O)NC(CCCNC(=N)N)C(=O)NC(CC3=CC=C(C=C3)O)C(=O)NC(CCCNC(=N)N)C(=O)NC(CCCCN)C(=O)NC(CCC(=O)N)C(=O)NC(CCSC)C(=O)NC(C)C(=O)NC(C(C)C)C(=O)NC(CCCCN)C(=O)NC(CCCCN)C(=O)NC(CC4=CC=C(C=C4)O)C(=O)NC(CC(C)C)C(=O)NC(C)C(=O)NC(C)C(=O)NC(C(C)C)C(=O)NC(CC(C)C)C(=O)N)NC(=O)CNC(=O)C(CC(=O)O)NC(=O)C(CO)NC(=O)C(CC5=CNC=N5)N Ambient -20°C "Nam BH, Moon JY, Kim YO, et al. Structural and functional characterization of pituitary adenylyl cyclase-activating polypeptide (PACAP)/PACAP-related peptide (PRP) and its receptor in olive flounder (Paralichthys olivaceus). Comp Biochem Physiol B Biochem Mol Biol. 2013 Jan;164(1):18-28. PMID: 23026070.

Tam JK, Lee LT, Cheng CH, et al. Discovery of a new reproductive hormone in teleosts: pituitary adenylate cyclase-activating polypeptide-related peptide (PRP). Gen Comp Endocrinol. 2011 Sep 15;173(3):405-10. PMID: 21703272.

Vaudry D, Falluel-Morel A, Bourgault S, et al. Pituitary adenylate cyclase-activating polypeptide and its receptors: 20 years after the discovery. Pharmacol Rev. 2009 Sep;61(3):283-357. PMID: 19805477.

Mei YA, Vaudry D, Basille M, et al. PACAP inhibits delayed rectifier potassium current via a cAMP/PKA transduction pathway: evidence for the involvement of I k in the anti-apoptotic action of PACAP. Eur J Neurosci. 2004 Mar;19(6):1446-58. PMID: 15066141.

" Not dangerous goods.

LKT P0005 Pituitary Adenylate Cyclase-activating Polypeptide (1-27), human, sheep, rat 1 mg 468.2 Endogenous peptide, involved in paracrine and autocrine cell signaling; PAC1 and VPAC1/2 agonist. PACAP (1-27) 127317-03-7 ≥95% 3147.68 C142H224N40O39S CCC(C)C(C(=O)NC(CC1=CC=CC=C1)C(=O)NC(C(C)O)C(=O)NC(CC(=O)O)C(=O)NC(CO)C(=O)NC(CC2=CC=C(C=C2)O)C(=O)NC(CO)C(=O)NC(CCCNC(=N)N)C(=O)NC(CC3=CC=C(C=C3)O)C(=O)NC(CCCNC(=N)N)C(=O)NC(CCCCN)C(=O)NC(CCC(=O)N)C(=O)NC(CCSC)C(=O)NC(C)C(=O)NC(C(C)C)C(=O)NC(CCCCN)C(=O)NC(CCCCN)C(=O)NC(CC4=CC=C(C=C4)O)C(=O)NC(CC(C)C)C(=O)NC(C)C(=O)NC(C)C(=O)NC(C(C)C)C(=O)NC(CC(C)C)C(=O)N)NC(=O)CNC(=O)C(CC(=O)O)NC(=O)C(CO)NC(=O)C(CC5=CNC=N5)N Ambient -20°C "Nam BH, Moon JY, Kim YO, et al. Structural and functional characterization of pituitary adenylyl cyclase-activating polypeptide (PACAP)/PACAP-related peptide (PRP) and its receptor in olive flounder (Paralichthys olivaceus). Comp Biochem Physiol B Biochem Mol Biol. 2013 Jan;164(1):18-28. PMID: 23026070.

Tam JK, Lee LT, Cheng CH, et al. Discovery of a new reproductive hormone in teleosts: pituitary adenylate cyclase-activating polypeptide-related peptide (PRP). Gen Comp Endocrinol. 2011 Sep 15;173(3):405-10. PMID: 21703272.

Vaudry D, Falluel-Morel A, Bourgault S, et al. Pituitary adenylate cyclase-activating polypeptide and its receptors: 20 years after the discovery. Pharmacol Rev. 2009 Sep;61(3):283-357. PMID: 19805477.

Mei YA, Vaudry D, Basille M, et al. PACAP inhibits delayed rectifier potassium current via a cAMP/PKA transduction pathway: evidence for the involvement of I k in the anti-apoptotic action of PACAP. Eur J Neurosci. 2004 Mar;19(6):1446-58. PMID: 15066141.

" Not dangerous goods.

LKT P9869 Pyridoxine Hydrochloride 100 g 112.5 Vitamin B6 derivative, antioxidant. 58-56-0 ≥98% 205.64 C8H11NO3HCl CC1=NC=C(C(=C1O)CO)CO.Cl Ambient Ambient Soluble in water (200 mg/mL), ethanol (8.5 mg/mL). "Xie L, Liu Z, Lu H, et al. Pyridoxine inhibits endothelial NOS uncoupling induced by oxidized low-density lipoprotein via the PKCα signaling pathway in human umbilical vein endothelial cells. Br J Pharmacol. 2012 Feb;165(3):754-64. PMID: 21797845.

Nakari M, Kanouchi H, Oka T. High dose of pyridoxine induces IGFBP-3 mRNA expression in MCF-7 cells and its induction is inhibited by the p53-specific inhibitor pifithrin-α. J Nutr Sci Vitaminol (Tokyo). 2011;57(4):280-4. PMID: 22041910.

Yang TT, Wang SJ. Pyridoxine inhibits depolarization-evoked glutamate release in nerve terminals from rat cerebral cortex: a possible neuroprotective mechanism? J Pharmacol Exp Ther. 2009 Oct;331(1):244-54. PMID: 19628631.

Wu Y, Liu Y, Han Y, et al. Pyridoxine increases nitric oxide biosynthesis in human platelets. Int J Vitam Nutr Res. 2009 Mar;79(2):95-103. PMID: 20108211.

Jain SK, Lim G. Pyridoxine and pyridoxamine inhibits superoxide radicals and prevents lipid peroxidation, protein glycosylation, and (Na+ + K+)-ATPase activity reduction in high glucose-treated human erythrocytes. Free Radic Biol Med. 2001 Feb 1;30(3):232-7. PMID: 11165869.

Ross JB, Moss MA. Relief of the photosensitivity of erythropoietic protoporphyria by pyridoxine. J Am Acad Dermatol. 1990 Feb;22(2 Pt 2):340-2. PMID: 2303590.

" None Not dangerous goods.

LKT P0005 Pituitary Adenylate Cyclase-activating Polypeptide (1-27), human, sheep, rat 2.5 mg 828.1 Endogenous peptide, involved in paracrine and autocrine cell signaling; PAC1 and VPAC1/2 agonist. PACAP (1-27) 127317-03-7 ≥95% 3147.68 C142H224N40O39S CCC(C)C(C(=O)NC(CC1=CC=CC=C1)C(=O)NC(C(C)O)C(=O)NC(CC(=O)O)C(=O)NC(CO)C(=O)NC(CC2=CC=C(C=C2)O)C(=O)NC(CO)C(=O)NC(CCCNC(=N)N)C(=O)NC(CC3=CC=C(C=C3)O)C(=O)NC(CCCNC(=N)N)C(=O)NC(CCCCN)C(=O)NC(CCC(=O)N)C(=O)NC(CCSC)C(=O)NC(C)C(=O)NC(C(C)C)C(=O)NC(CCCCN)C(=O)NC(CCCCN)C(=O)NC(CC4=CC=C(C=C4)O)C(=O)NC(CC(C)C)C(=O)NC(C)C(=O)NC(C)C(=O)NC(C(C)C)C(=O)NC(CC(C)C)C(=O)N)NC(=O)CNC(=O)C(CC(=O)O)NC(=O)C(CO)NC(=O)C(CC5=CNC=N5)N Ambient -20°C "Nam BH, Moon JY, Kim YO, et al. Structural and functional characterization of pituitary adenylyl cyclase-activating polypeptide (PACAP)/PACAP-related peptide (PRP) and its receptor in olive flounder (Paralichthys olivaceus). Comp Biochem Physiol B Biochem Mol Biol. 2013 Jan;164(1):18-28. PMID: 23026070.

Tam JK, Lee LT, Cheng CH, et al. Discovery of a new reproductive hormone in teleosts: pituitary adenylate cyclase-activating polypeptide-related peptide (PRP). Gen Comp Endocrinol. 2011 Sep 15;173(3):405-10. PMID: 21703272.

Vaudry D, Falluel-Morel A, Bourgault S, et al. Pituitary adenylate cyclase-activating polypeptide and its receptors: 20 years after the discovery. Pharmacol Rev. 2009 Sep;61(3):283-357. PMID: 19805477.

Mei YA, Vaudry D, Basille M, et al. PACAP inhibits delayed rectifier potassium current via a cAMP/PKA transduction pathway: evidence for the involvement of I k in the anti-apoptotic action of PACAP. Eur J Neurosci. 2004 Mar;19(6):1446-58. PMID: 15066141.

" Not dangerous goods.

LKT P0006 Pituitary Adenylate Cyclase-activating Polypeptide (1-38), human, sheep, rat 2.5 mg 1116.2 Endogenous peptide, involved in paracrine and autocrine cell signaling; PAC1 and VPAC1/2 agonist. PACAP (1-38) 124123-15-5 ≥95% 4534.36 C203H331N63O53S CCC(C)C(C(=O)NC(CC1=CC=CC=C1)C(=O)NC(C(C)O)C(=O)NC(CC(=O)O)C(=O)NC(CO)C(=O)NC(CC2=CC=C(C=C2)O)C(=O)NC(CO)C(=O)NC(CCCNC(=N)N)C(=O)NC(CC3=CC=C(C=C3)O)C(=O)NC(CCCNC(=N)N)C(=O)NC(CCCCN)C(=O)NC(CCC(=O)N)C(=O)NC(CCSC)C(=O)NC(C)C(=O)NC(C(C)C)C(=O)NC(CCCCN)C(=O)NC(CCCCN)C(=O)NC(CC4=CC=C(C=C4)O)C(=O)NC(CC(C)C)C(=O)NC(C)C(=O)NC(C)C(=O)NC(C(C)C)C(=O)NC(CC(C)C)C(=O)NCC(=O)NC(CCCCN)C(=O)NC(CCCNC(=N)N)C(=O)NC(CC5=CC=C(C=C5)O)C(=O)NC(CCCCN)C(=O)NC(CCC(=O)N)C(=O)NC(CCCNC(=N)N)C(=O)NC(C(C)C)C(=O)NC(CCCCN)C(=O)NC(CC(=O)N)C(=O)NC(CCCCN)C(=O)N)NC(=O)CNC(=O)C(CC(=O)O)NC(=O)C(CO)NC(=O)C(CC6=CN=CN6)N Ambient -20°C "Nam BH, Moon JY, Kim YO, et al. Structural and functional characterization of pituitary adenylyl cyclase-activating polypeptide (PACAP)/PACAP-related peptide (PRP) and its receptor in olive flounder (Paralichthys olivaceus). Comp Biochem Physiol B Biochem Mol Biol. 2013 Jan;164(1):18-28. PMID: 23026070.

Tam JK, Lee LT, Cheng CH, et al. Discovery of a new reproductive hormone in teleosts: pituitary adenylate cyclase-activating polypeptide-related peptide (PRP). Gen Comp Endocrinol. 2011 Sep 15;173(3):405-10. PMID: 21703272.

Vaudry D, Falluel-Morel A, Bourgault S, et al. Pituitary adenylate cyclase-activating polypeptide and its receptors: 20 years after the discovery. Pharmacol Rev. 2009 Sep;61(3):283-357. PMID: 19805477.

Mei YA, Vaudry D, Basille M, et al. PACAP inhibits delayed rectifier potassium current via a cAMP/PKA transduction pathway: evidence for the involvement of I k in the anti-apoptotic action of PACAP. Eur J Neurosci. 2004 Mar;19(6):1446-58. PMID: 15066141.

" Not dangerous goods.

LKT P0006 Pituitary Adenylate Cyclase-activating Polypeptide (1-38), human, sheep, rat 1 mg 633 Endogenous peptide, involved in paracrine and autocrine cell signaling; PAC1 and VPAC1/2 agonist. PACAP (1-38) 124123-15-5 ≥95% 4534.36 C203H331N63O53S CCC(C)C(C(=O)NC(CC1=CC=CC=C1)C(=O)NC(C(C)O)C(=O)NC(CC(=O)O)C(=O)NC(CO)C(=O)NC(CC2=CC=C(C=C2)O)C(=O)NC(CO)C(=O)NC(CCCNC(=N)N)C(=O)NC(CC3=CC=C(C=C3)O)C(=O)NC(CCCNC(=N)N)C(=O)NC(CCCCN)C(=O)NC(CCC(=O)N)C(=O)NC(CCSC)C(=O)NC(C)C(=O)NC(C(C)C)C(=O)NC(CCCCN)C(=O)NC(CCCCN)C(=O)NC(CC4=CC=C(C=C4)O)C(=O)NC(CC(C)C)C(=O)NC(C)C(=O)NC(C)C(=O)NC(C(C)C)C(=O)NC(CC(C)C)C(=O)NCC(=O)NC(CCCCN)C(=O)NC(CCCNC(=N)N)C(=O)NC(CC5=CC=C(C=C5)O)C(=O)NC(CCCCN)C(=O)NC(CCC(=O)N)C(=O)NC(CCCNC(=N)N)C(=O)NC(C(C)C)C(=O)NC(CCCCN)C(=O)NC(CC(=O)N)C(=O)NC(CCCCN)C(=O)N)NC(=O)CNC(=O)C(CC(=O)O)NC(=O)C(CO)NC(=O)C(CC6=CN=CN6)N Ambient -20°C "Nam BH, Moon JY, Kim YO, et al. Structural and functional characterization of pituitary adenylyl cyclase-activating polypeptide (PACAP)/PACAP-related peptide (PRP) and its receptor in olive flounder (Paralichthys olivaceus). Comp Biochem Physiol B Biochem Mol Biol. 2013 Jan;164(1):18-28. PMID: 23026070.

Tam JK, Lee LT, Cheng CH, et al. Discovery of a new reproductive hormone in teleosts: pituitary adenylate cyclase-activating polypeptide-related peptide (PRP). Gen Comp Endocrinol. 2011 Sep 15;173(3):405-10. PMID: 21703272.

Vaudry D, Falluel-Morel A, Bourgault S, et al. Pituitary adenylate cyclase-activating polypeptide and its receptors: 20 years after the discovery. Pharmacol Rev. 2009 Sep;61(3):283-357. PMID: 19805477.

Mei YA, Vaudry D, Basille M, et al. PACAP inhibits delayed rectifier potassium current via a cAMP/PKA transduction pathway: evidence for the involvement of I k in the anti-apoptotic action of PACAP. Eur J Neurosci. 2004 Mar;19(6):1446-58. PMID: 15066141.

" Not dangerous goods.

LKT P0006 Pituitary Adenylate Cyclase-activating Polypeptide (1-38), human, sheep, rat 0.5 mg 372.1 Endogenous peptide, involved in paracrine and autocrine cell signaling; PAC1 and VPAC1/2 agonist. PACAP (1-38) 124123-15-5 ≥95% 4534.36 C203H331N63O53S CCC(C)C(C(=O)NC(CC1=CC=CC=C1)C(=O)NC(C(C)O)C(=O)NC(CC(=O)O)C(=O)NC(CO)C(=O)NC(CC2=CC=C(C=C2)O)C(=O)NC(CO)C(=O)NC(CCCNC(=N)N)C(=O)NC(CC3=CC=C(C=C3)O)C(=O)NC(CCCNC(=N)N)C(=O)NC(CCCCN)C(=O)NC(CCC(=O)N)C(=O)NC(CCSC)C(=O)NC(C)C(=O)NC(C(C)C)C(=O)NC(CCCCN)C(=O)NC(CCCCN)C(=O)NC(CC4=CC=C(C=C4)O)C(=O)NC(CC(C)C)C(=O)NC(C)C(=O)NC(C)C(=O)NC(C(C)C)C(=O)NC(CC(C)C)C(=O)NCC(=O)NC(CCCCN)C(=O)NC(CCCNC(=N)N)C(=O)NC(CC5=CC=C(C=C5)O)C(=O)NC(CCCCN)C(=O)NC(CCC(=O)N)C(=O)NC(CCCNC(=N)N)C(=O)NC(C(C)C)C(=O)NC(CCCCN)C(=O)NC(CC(=O)N)C(=O)NC(CCCCN)C(=O)N)NC(=O)CNC(=O)C(CC(=O)O)NC(=O)C(CO)NC(=O)C(CC6=CN=CN6)N Ambient -20°C "Nam BH, Moon JY, Kim YO, et al. Structural and functional characterization of pituitary adenylyl cyclase-activating polypeptide (PACAP)/PACAP-related peptide (PRP) and its receptor in olive flounder (Paralichthys olivaceus). Comp Biochem Physiol B Biochem Mol Biol. 2013 Jan;164(1):18-28. PMID: 23026070.

Tam JK, Lee LT, Cheng CH, et al. Discovery of a new reproductive hormone in teleosts: pituitary adenylate cyclase-activating polypeptide-related peptide (PRP). Gen Comp Endocrinol. 2011 Sep 15;173(3):405-10. PMID: 21703272.

Vaudry D, Falluel-Morel A, Bourgault S, et al. Pituitary adenylate cyclase-activating polypeptide and its receptors: 20 years after the discovery. Pharmacol Rev. 2009 Sep;61(3):283-357. PMID: 19805477.

Mei YA, Vaudry D, Basille M, et al. PACAP inhibits delayed rectifier potassium current via a cAMP/PKA transduction pathway: evidence for the involvement of I k in the anti-apoptotic action of PACAP. Eur J Neurosci. 2004 Mar;19(6):1446-58. PMID: 15066141.

" Not dangerous goods.

LKT P0007 Pituitary Adenylate Cyclase-activating Polypeptide (6-27), human, sheep, rat 0.5 mg 204.1 Endogenous peptide, involved in paracrine and autocrine cell signaling; PAC1 and VPAC1/2 agonist. PACAP (6-27) ≥95% 2638.1 C203H331N63O65S Ambient -20°C "Nam BH, Moon JY, Kim YO, et al. Structural and functional characterization of pituitary adenylyl cyclase-activating polypeptide (PACAP)/PACAP-related peptide (PRP) and its receptor in olive flounder (Paralichthys olivaceus). Comp Biochem Physiol B Biochem Mol Biol. 2013 Jan;164(1):18-28. PMID: 23026070.

Tam JK, Lee LT, Cheng CH, et al. Discovery of a new reproductive hormone in teleosts: pituitary adenylate cyclase-activating polypeptide-related peptide (PRP). Gen Comp Endocrinol. 2011 Sep 15;173(3):405-10. PMID: 21703272.

Vaudry D, Falluel-Morel A, Bourgault S, et al. Pituitary adenylate cyclase-activating polypeptide and its receptors: 20 years after the discovery. Pharmacol Rev. 2009 Sep;61(3):283-357. PMID: 19805477.

Mei YA, Vaudry D, Basille M, et al. PACAP inhibits delayed rectifier potassium current via a cAMP/PKA transduction pathway: evidence for the involvement of I k in the anti-apoptotic action of PACAP. Eur J Neurosci. 2004 Mar;19(6):1446-58. PMID: 15066141.

" Not dangerous goods.

LKT P0007 Pituitary Adenylate Cyclase-activating Polypeptide (6-27), human, sheep, rat 1 mg 348 Endogenous peptide, involved in paracrine and autocrine cell signaling; PAC1 and VPAC1/2 agonist. PACAP (6-27) ≥95% 2638.1 C203H331N63O65S Ambient -20°C "Nam BH, Moon JY, Kim YO, et al. Structural and functional characterization of pituitary adenylyl cyclase-activating polypeptide (PACAP)/PACAP-related peptide (PRP) and its receptor in olive flounder (Paralichthys olivaceus). Comp Biochem Physiol B Biochem Mol Biol. 2013 Jan;164(1):18-28. PMID: 23026070.

Tam JK, Lee LT, Cheng CH, et al. Discovery of a new reproductive hormone in teleosts: pituitary adenylate cyclase-activating polypeptide-related peptide (PRP). Gen Comp Endocrinol. 2011 Sep 15;173(3):405-10. PMID: 21703272.

Vaudry D, Falluel-Morel A, Bourgault S, et al. Pituitary adenylate cyclase-activating polypeptide and its receptors: 20 years after the discovery. Pharmacol Rev. 2009 Sep;61(3):283-357. PMID: 19805477.

Mei YA, Vaudry D, Basille M, et al. PACAP inhibits delayed rectifier potassium current via a cAMP/PKA transduction pathway: evidence for the involvement of I k in the anti-apoptotic action of PACAP. Eur J Neurosci. 2004 Mar;19(6):1446-58. PMID: 15066141.

" Not dangerous goods.

LKT P0007 Pituitary Adenylate Cyclase-activating Polypeptide (6-27), human, sheep, rat 2.5 mg 612.4 Endogenous peptide, involved in paracrine and autocrine cell signaling; PAC1 and VPAC1/2 agonist. PACAP (6-27) ≥95% 2638.1 C203H331N63O65S Ambient -20°C "Nam BH, Moon JY, Kim YO, et al. Structural and functional characterization of pituitary adenylyl cyclase-activating polypeptide (PACAP)/PACAP-related peptide (PRP) and its receptor in olive flounder (Paralichthys olivaceus). Comp Biochem Physiol B Biochem Mol Biol. 2013 Jan;164(1):18-28. PMID: 23026070.

Tam JK, Lee LT, Cheng CH, et al. Discovery of a new reproductive hormone in teleosts: pituitary adenylate cyclase-activating polypeptide-related peptide (PRP). Gen Comp Endocrinol. 2011 Sep 15;173(3):405-10. PMID: 21703272.

Vaudry D, Falluel-Morel A, Bourgault S, et al. Pituitary adenylate cyclase-activating polypeptide and its receptors: 20 years after the discovery. Pharmacol Rev. 2009 Sep;61(3):283-357. PMID: 19805477.

Mei YA, Vaudry D, Basille M, et al. PACAP inhibits delayed rectifier potassium current via a cAMP/PKA transduction pathway: evidence for the involvement of I k in the anti-apoptotic action of PACAP. Eur J Neurosci. 2004 Mar;19(6):1446-58. PMID: 15066141.

" Not dangerous goods.

LKT P9770 Pyrrolostatin 100 µg 124.1 Antioxidant. "1H-Pyrrole-2-carboxylic acid, 4-(3,7-dimethyl-2,6-

octadienyl)-, (E)-" EC 40 144314-68-1 ≥98% 247.33 C15H21NO2 CC(=CCCC(=CCC1=CNC(=C1)C(=O)O)C)C Protect from light. Dry Ice -20°C Soluble in methanol, ethanol, or DMSO. Insoluble in water. "Chekanov VS, Maternowski MA, Eisenstein R, et al. Angiogenesis in the latissimus dorsi muscle using different regimens of electrical stimulation and pharmaceutical support. ASAIO J. 2000 May-Jun;46(3):305-12. PMID: 10826742.

Kato S, Shindo K, Kawai H, et al. Pyrrolostatin, a novel lipid peroxidation inhibitor from Streptomyces chrestomyceticus. Taxonomy, fermentation, isolation, structure elucidation and biological properties. J Antibiot (Tokyo). 1993 Jun;46(6):892-9. PMID: 8344870.

" Not dangerous goods.

LKT P9770 Pyrrolostatin 1 mg 303.2 Antioxidant. "1H-Pyrrole-2-carboxylic acid, 4-(3,7-dimethyl-2,6-

octadienyl)-, (E)-" EC 40 144314-68-1 ≥98% 247.33 C15H21NO2 CC(=CCCC(=CCC1=CNC(=C1)C(=O)O)C)C Protect from light. Dry Ice -20°C Soluble in methanol, ethanol, or DMSO. Insoluble in water. "Chekanov VS, Maternowski MA, Eisenstein R, et al. Angiogenesis in the latissimus dorsi muscle using different regimens of electrical stimulation and pharmaceutical support. ASAIO J. 2000 May-Jun;46(3):305-12. PMID: 10826742.

Kato S, Shindo K, Kawai H, et al. Pyrrolostatin, a novel lipid peroxidation inhibitor from Streptomyces chrestomyceticus. Taxonomy, fermentation, isolation, structure elucidation and biological properties. J Antibiot (Tokyo). 1993 Jun;46(6):892-9. PMID: 8344870.

" Not dangerous goods.

LKT P0008 Pituitary Adenylate Cyclase-activating Peptide (6-38), human/sheep/rat 0.5 mg 348 Endogenous peptide, involved in paracrine and autocrine cell signaling; PAC1 and VPAC1/2 agonist. PACAP 137061-48-4 ≥95% 4024.8 C203H331N63O65S Ambient -20°C "Nam BH, Moon JY, Kim YO, et al. Structural and functional characterization of pituitary adenylyl cyclase-activating polypeptide (PACAP)/PACAP-related peptide (PRP) and its receptor in olive flounder (Paralichthys olivaceus). Comp Biochem Physiol B Biochem Mol Biol. 2013 Jan;164(1):18-28. PMID: 23026070.

Tam JK, Lee LT, Cheng CH, et al. Discovery of a new reproductive hormone in teleosts: pituitary adenylate cyclase-activating polypeptide-related peptide (PRP). Gen Comp Endocrinol. 2011 Sep 15;173(3):405-10. PMID: 21703272.

Vaudry D, Falluel-Morel A, Bourgault S, et al. Pituitary adenylate cyclase-activating polypeptide and its receptors: 20 years after the discovery. Pharmacol Rev. 2009 Sep;61(3):283-357. PMID: 19805477.

Mei YA, Vaudry D, Basille M, et al. PACAP inhibits delayed rectifier potassium current via a cAMP/PKA transduction pathway: evidence for the involvement of I k in the anti-apoptotic action of PACAP. Eur J Neurosci. 2004 Mar;19(6):1446-58. PMID: 15066141.

" Not dangerous goods.

LKT P0008 Pituitary Adenylate Cyclase-activating Peptide (6-38), human/sheep/rat 1 mg 591 Endogenous peptide, involved in paracrine and autocrine cell signaling; PAC1 and VPAC1/2 agonist. PACAP 137061-48-4 ≥95% 4024.8 C203H331N63O65S Ambient -20°C "Nam BH, Moon JY, Kim YO, et al. Structural and functional characterization of pituitary adenylyl cyclase-activating polypeptide (PACAP)/PACAP-related peptide (PRP) and its receptor in olive flounder (Paralichthys olivaceus). Comp Biochem Physiol B Biochem Mol Biol. 2013 Jan;164(1):18-28. PMID: 23026070.

Tam JK, Lee LT, Cheng CH, et al. Discovery of a new reproductive hormone in teleosts: pituitary adenylate cyclase-activating polypeptide-related peptide (PRP). Gen Comp Endocrinol. 2011 Sep 15;173(3):405-10. PMID: 21703272.

Vaudry D, Falluel-Morel A, Bourgault S, et al. Pituitary adenylate cyclase-activating polypeptide and its receptors: 20 years after the discovery. Pharmacol Rev. 2009 Sep;61(3):283-357. PMID: 19805477.

Mei YA, Vaudry D, Basille M, et al. PACAP inhibits delayed rectifier potassium current via a cAMP/PKA transduction pathway: evidence for the involvement of I k in the anti-apoptotic action of PACAP. Eur J Neurosci. 2004 Mar;19(6):1446-58. PMID: 15066141.

" Not dangerous goods.

LKT P0008 Pituitary Adenylate Cyclase-activating Peptide (6-38), human/sheep/rat 2.5 mg 1043.9 Endogenous peptide, involved in paracrine and autocrine cell signaling; PAC1 and VPAC1/2 agonist. PACAP 137061-48-4 ≥95% 4024.8 C203H331N63O65S Ambient -20°C "Nam BH, Moon JY, Kim YO, et al. Structural and functional characterization of pituitary adenylyl cyclase-activating polypeptide (PACAP)/PACAP-related peptide (PRP) and its receptor in olive flounder (Paralichthys olivaceus). Comp Biochem Physiol B Biochem Mol Biol. 2013 Jan;164(1):18-28. PMID: 23026070.

Tam JK, Lee LT, Cheng CH, et al. Discovery of a new reproductive hormone in teleosts: pituitary adenylate cyclase-activating polypeptide-related peptide (PRP). Gen Comp Endocrinol. 2011 Sep 15;173(3):405-10. PMID: 21703272.

Vaudry D, Falluel-Morel A, Bourgault S, et al. Pituitary adenylate cyclase-activating polypeptide and its receptors: 20 years after the discovery. Pharmacol Rev. 2009 Sep;61(3):283-357. PMID: 19805477.

Mei YA, Vaudry D, Basille M, et al. PACAP inhibits delayed rectifier potassium current via a cAMP/PKA transduction pathway: evidence for the involvement of I k in the anti-apoptotic action of PACAP. Eur J Neurosci. 2004 Mar;19(6):1446-58. PMID: 15066141.

" Not dangerous goods.

LKT P0009 Pituitary Adenylate Cyclase-activating Polypeptide (1-38), frog 0.5 mg 420.1 Endogenous peptide, involved in paracrine and autocrine cell signaling; PAC1 and VPAC1/2 agonist. PACAP ≥95% 4548.38 C204H333N63O53S Ambient -20°C "Nam BH, Moon JY, Kim YO, et al. Structural and functional characterization of pituitary adenylyl cyclase-activating polypeptide (PACAP)/PACAP-related peptide (PRP) and its receptor in olive flounder (Paralichthys olivaceus). Comp Biochem Physiol B Biochem Mol Biol. 2013 Jan;164(1):18-28. PMID: 23026070.

Tam JK, Lee LT, Cheng CH, et al. Discovery of a new reproductive hormone in teleosts: pituitary adenylate cyclase-activating polypeptide-related peptide (PRP). Gen Comp Endocrinol. 2011 Sep 15;173(3):405-10. PMID: 21703272.

Vaudry D, Falluel-Morel A, Bourgault S, et al. Pituitary adenylate cyclase-activating polypeptide and its receptors: 20 years after the discovery. Pharmacol Rev. 2009 Sep;61(3):283-357. PMID: 19805477.

Mei YA, Vaudry D, Basille M, et al. PACAP inhibits delayed rectifier potassium current via a cAMP/PKA transduction pathway: evidence for the involvement of I k in the anti-apoptotic action of PACAP. Eur J Neurosci. 2004 Mar;19(6):1446-58. PMID: 15066141.

" Not dangerous goods.

LKT P0009 Pituitary Adenylate Cyclase-activating Polypeptide (1-38), frog 1 mg 714.2 Endogenous peptide, involved in paracrine and autocrine cell signaling; PAC1 and VPAC1/2 agonist. PACAP ≥95% 4548.38 C204H333N63O53S Ambient -20°C "Nam BH, Moon JY, Kim YO, et al. Structural and functional characterization of pituitary adenylyl cyclase-activating polypeptide (PACAP)/PACAP-related peptide (PRP) and its receptor in olive flounder (Paralichthys olivaceus). Comp Biochem Physiol B Biochem Mol Biol. 2013 Jan;164(1):18-28. PMID: 23026070.

Tam JK, Lee LT, Cheng CH, et al. Discovery of a new reproductive hormone in teleosts: pituitary adenylate cyclase-activating polypeptide-related peptide (PRP). Gen Comp Endocrinol. 2011 Sep 15;173(3):405-10. PMID: 21703272.

Vaudry D, Falluel-Morel A, Bourgault S, et al. Pituitary adenylate cyclase-activating polypeptide and its receptors: 20 years after the discovery. Pharmacol Rev. 2009 Sep;61(3):283-357. PMID: 19805477.

Mei YA, Vaudry D, Basille M, et al. PACAP inhibits delayed rectifier potassium current via a cAMP/PKA transduction pathway: evidence for the involvement of I k in the anti-apoptotic action of PACAP. Eur J Neurosci. 2004 Mar;19(6):1446-58. PMID: 15066141.

" Not dangerous goods.

LKT P0009 Pituitary Adenylate Cyclase-activating Polypeptide (1-38), frog 2.5 mg 1260.1 Endogenous peptide, involved in paracrine and autocrine cell signaling; PAC1 and VPAC1/2 agonist. PACAP ≥95% 4548.38 C204H333N63O53S Ambient -20°C "Nam BH, Moon JY, Kim YO, et al. Structural and functional characterization of pituitary adenylyl cyclase-activating polypeptide (PACAP)/PACAP-related peptide (PRP) and its receptor in olive flounder (Paralichthys olivaceus). Comp Biochem Physiol B Biochem Mol Biol. 2013 Jan;164(1):18-28. PMID: 23026070.

Tam JK, Lee LT, Cheng CH, et al. Discovery of a new reproductive hormone in teleosts: pituitary adenylate cyclase-activating polypeptide-related peptide (PRP). Gen Comp Endocrinol. 2011 Sep 15;173(3):405-10. PMID: 21703272.

Vaudry D, Falluel-Morel A, Bourgault S, et al. Pituitary adenylate cyclase-activating polypeptide and its receptors: 20 years after the discovery. Pharmacol Rev. 2009 Sep;61(3):283-357. PMID: 19805477.

Mei YA, Vaudry D, Basille M, et al. PACAP inhibits delayed rectifier potassium current via a cAMP/PKA transduction pathway: evidence for the involvement of I k in the anti-apoptotic action of PACAP. Eur J Neurosci. 2004 Mar;19(6):1446-58. PMID: 15066141.

" Not dangerous goods.

LKT P0010 Pituitary Adenylate Cyclase-activating Polypeptide-related Peptide, human 0.5 mg 300.1 Peptide, involved in paracrine and autocrine cell signaling; PAC1 and VPAC1/2 agonist. PACAP-related peptide, PRP ≥95% 3146.62 C139H229N41O42 Ambient -20°C "Nam BH, Moon JY, Kim YO, et al. Structural and functional characterization of pituitary adenylyl cyclase-activating polypeptide (PACAP)/PACAP-related peptide (PRP) and its receptor in olive flounder (Paralichthys olivaceus). Comp Biochem Physiol B Biochem Mol Biol. 2013 Jan;164(1):18-28. PMID: 23026070.

Tam JK, Lee LT, Cheng CH, et al. Discovery of a new reproductive hormone in teleosts: pituitary adenylate cyclase-activating polypeptide-related peptide (PRP). Gen Comp Endocrinol. 2011 Sep 15;173(3):405-10. PMID: 21703272.

Vaudry D, Falluel-Morel A, Bourgault S, et al. Pituitary adenylate cyclase-activating polypeptide and its receptors: 20 years after the discovery. Pharmacol Rev. 2009 Sep;61(3):283-357. PMID: 19805477.

Mei YA, Vaudry D, Basille M, et al. PACAP inhibits delayed rectifier potassium current via a cAMP/PKA transduction pathway: evidence for the involvement of I k in the anti-apoptotic action of PACAP. Eur J Neurosci. 2004 Mar;19(6):1446-58. PMID: 15066141.

" Not dangerous goods.

LKT P0010 Pituitary Adenylate Cyclase-activating Polypeptide-related Peptide, human 1 mg 510 Peptide, involved in paracrine and autocrine cell signaling; PAC1 and VPAC1/2 agonist. PACAP-related peptide, PRP ≥95% 3146.62 C139H229N41O42 Ambient -20°C "Nam BH, Moon JY, Kim YO, et al. Structural and functional characterization of pituitary adenylyl cyclase-activating polypeptide (PACAP)/PACAP-related peptide (PRP) and its receptor in olive flounder (Paralichthys olivaceus). Comp Biochem Physiol B Biochem Mol Biol. 2013 Jan;164(1):18-28. PMID: 23026070.

Tam JK, Lee LT, Cheng CH, et al. Discovery of a new reproductive hormone in teleosts: pituitary adenylate cyclase-activating polypeptide-related peptide (PRP). Gen Comp Endocrinol. 2011 Sep 15;173(3):405-10. PMID: 21703272.

Vaudry D, Falluel-Morel A, Bourgault S, et al. Pituitary adenylate cyclase-activating polypeptide and its receptors: 20 years after the discovery. Pharmacol Rev. 2009 Sep;61(3):283-357. PMID: 19805477.

Mei YA, Vaudry D, Basille M, et al. PACAP inhibits delayed rectifier potassium current via a cAMP/PKA transduction pathway: evidence for the involvement of I k in the anti-apoptotic action of PACAP. Eur J Neurosci. 2004 Mar;19(6):1446-58. PMID: 15066141.

" Not dangerous goods.

LKT P0010 Pituitary Adenylate Cyclase-activating Polypeptide-related Peptide, human 2.5 mg 900.1 Peptide, involved in paracrine and autocrine cell signaling; PAC1 and VPAC1/2 agonist. PACAP-related peptide, PRP ≥95% 3146.62 C139H229N41O42 Ambient -20°C "Nam BH, Moon JY, Kim YO, et al. Structural and functional characterization of pituitary adenylyl cyclase-activating polypeptide (PACAP)/PACAP-related peptide (PRP) and its receptor in olive flounder (Paralichthys olivaceus). Comp Biochem Physiol B Biochem Mol Biol. 2013 Jan;164(1):18-28. PMID: 23026070.

Tam JK, Lee LT, Cheng CH, et al. Discovery of a new reproductive hormone in teleosts: pituitary adenylate cyclase-activating polypeptide-related peptide (PRP). Gen Comp Endocrinol. 2011 Sep 15;173(3):405-10. PMID: 21703272.

Vaudry D, Falluel-Morel A, Bourgault S, et al. Pituitary adenylate cyclase-activating polypeptide and its receptors: 20 years after the discovery. Pharmacol Rev. 2009 Sep;61(3):283-357. PMID: 19805477.

Mei YA, Vaudry D, Basille M, et al. PACAP inhibits delayed rectifier potassium current via a cAMP/PKA transduction pathway: evidence for the involvement of I k in the anti-apoptotic action of PACAP. Eur J Neurosci. 2004 Mar;19(6):1446-58. PMID: 15066141.

" Not dangerous goods.

LKT P0011 Pituitary Adenylate Cyclase-activating Polypeptide-related Peptide, rat 0.5 mg 300.1 Peptide, involved in paracrine and autocrine cell signaling; PAC1 and VPAC1/2 agonist. PACAP-related peptide, PRP ≥95% 3361.9 C148H242N42O45S1 Ambient -20°C "Nam BH, Moon JY, Kim YO, et al. Structural and functional characterization of pituitary adenylyl cyclase-activating polypeptide (PACAP)/PACAP-related peptide (PRP) and its receptor in olive flounder (Paralichthys olivaceus). Comp Biochem Physiol B Biochem Mol Biol. 2013 Jan;164(1):18-28. PMID: 23026070.

Tam JK, Lee LT, Cheng CH, et al. Discovery of a new reproductive hormone in teleosts: pituitary adenylate cyclase-activating polypeptide-related peptide (PRP). Gen Comp Endocrinol. 2011 Sep 15;173(3):405-10. PMID: 21703272.

Vaudry D, Falluel-Morel A, Bourgault S, et al. Pituitary adenylate cyclase-activating polypeptide and its receptors: 20 years after the discovery. Pharmacol Rev. 2009 Sep;61(3):283-357. PMID: 19805477.

Mei YA, Vaudry D, Basille M, et al. PACAP inhibits delayed rectifier potassium current via a cAMP/PKA transduction pathway: evidence for the involvement of I k in the anti-apoptotic action of PACAP. Eur J Neurosci. 2004 Mar;19(6):1446-58. PMID: 15066141.

" Not dangerous goods.

LKT P0011 Pituitary Adenylate Cyclase-activating Polypeptide-related Peptide, rat 1 mg 510 Peptide, involved in paracrine and autocrine cell signaling; PAC1 and VPAC1/2 agonist. PACAP-related peptide, PRP ≥95% 3361.9 C148H242N42O45S1 Ambient -20°C "Nam BH, Moon JY, Kim YO, et al. Structural and functional characterization of pituitary adenylyl cyclase-activating polypeptide (PACAP)/PACAP-related peptide (PRP) and its receptor in olive flounder (Paralichthys olivaceus). Comp Biochem Physiol B Biochem Mol Biol. 2013 Jan;164(1):18-28. PMID: 23026070.

Tam JK, Lee LT, Cheng CH, et al. Discovery of a new reproductive hormone in teleosts: pituitary adenylate cyclase-activating polypeptide-related peptide (PRP). Gen Comp Endocrinol. 2011 Sep 15;173(3):405-10. PMID: 21703272.

Vaudry D, Falluel-Morel A, Bourgault S, et al. Pituitary adenylate cyclase-activating polypeptide and its receptors: 20 years after the discovery. Pharmacol Rev. 2009 Sep;61(3):283-357. PMID: 19805477.

Mei YA, Vaudry D, Basille M, et al. PACAP inhibits delayed rectifier potassium current via a cAMP/PKA transduction pathway: evidence for the involvement of I k in the anti-apoptotic action of PACAP. Eur J Neurosci. 2004 Mar;19(6):1446-58. PMID: 15066141.

" Not dangerous goods.

LKT P0011 Pituitary Adenylate Cyclase-activating Polypeptide-related Peptide, rat 2.5 mg 900.1 Peptide, involved in paracrine and autocrine cell signaling; PAC1 and VPAC1/2 agonist. PACAP-related peptide, PRP ≥95% 3361.9 C148H242N42O45S1 Ambient -20°C "Nam BH, Moon JY, Kim YO, et al. Structural and functional characterization of pituitary adenylyl cyclase-activating polypeptide (PACAP)/PACAP-related peptide (PRP) and its receptor in olive flounder (Paralichthys olivaceus). Comp Biochem Physiol B Biochem Mol Biol. 2013 Jan;164(1):18-28. PMID: 23026070.

Tam JK, Lee LT, Cheng CH, et al. Discovery of a new reproductive hormone in teleosts: pituitary adenylate cyclase-activating polypeptide-related peptide (PRP). Gen Comp Endocrinol. 2011 Sep 15;173(3):405-10. PMID: 21703272.

Vaudry D, Falluel-Morel A, Bourgault S, et al. Pituitary adenylate cyclase-activating polypeptide and its receptors: 20 years after the discovery. Pharmacol Rev. 2009 Sep;61(3):283-357. PMID: 19805477.

Mei YA, Vaudry D, Basille M, et al. PACAP inhibits delayed rectifier potassium current via a cAMP/PKA transduction pathway: evidence for the involvement of I k in the anti-apoptotic action of PACAP. Eur J Neurosci. 2004 Mar;19(6):1446-58. PMID: 15066141.

" Not dangerous goods.

LKT P9768 Pyronaridine Tetraphosphate 100 mg 121.4 Hemantin inhibitor. 4-[(7-Chloro-2-methoxybenzo[b]-1,5-naphthyridin-10-yl)amino]-2,6-bis(1-pyrrolidinylmethyl)phenol tetraphosphate Malaridine 76748-86-2 ≥98% 910.03 C29H32ClN5O2 4H3PO4 COC1=CC=C2C(=C(C3=C(N2)C=C(C=C3)Cl)N=C4C=C(C(=O)C(=C4)CN5CCCC5)CN6CCCC6)N1.OP(=O)(O)O.OP(=O)(O)O.OP(=O)(O)O.OP(=O)(O)O Ambient Ambient Soluble in water.  Very sparingly soluble in ethanol. "Henrich PP, O'Brien C, Sáenz FE, et al. Evidence for pyronaridine as a highly effective partner drug for treatment of artemisinin-resistant malaria in a rodent model. Antimicrob Agents Chemother. 2014 Jan;58(1):183-95. PMID: 24145526.

Kritsiriwuthinan K, Chaotheing S, Shaw PJ, et al. Global gene expression profiling of Plasmodium falciparum in response to the anti-malarial drug pyronaridine. Malar J. 2011 Aug 18;10:242. PMID: 21849091.

Auparakkitanon S, Chapoomram S, Kuaha K, et al. Targeting of hematin by the antimalarial pyronaridine. Antimicrob Agents Chemother. 2006 Jun;50(6):2197-200. PMID: 16723583.

" Xn Not dangerous goods.

LKT P9768 Pyronaridine Tetraphosphate 250 mg 236.6 Hemantin inhibitor. 4-[(7-Chloro-2-methoxybenzo[b]-1,5-naphthyridin-10-yl)amino]-2,6-bis(1-pyrrolidinylmethyl)phenol tetraphosphate Malaridine 76748-86-2 ≥98% 910.03 C29H32ClN5O2 4H3PO4 COC1=CC=C2C(=C(C3=C(N2)C=C(C=C3)Cl)N=C4C=C(C(=O)C(=C4)CN5CCCC5)CN6CCCC6)N1.OP(=O)(O)O.OP(=O)(O)O.OP(=O)(O)O.OP(=O)(O)O Ambient Ambient Soluble in water.  Very sparingly soluble in ethanol. "Henrich PP, O'Brien C, Sáenz FE, et al. Evidence for pyronaridine as a highly effective partner drug for treatment of artemisinin-resistant malaria in a rodent model. Antimicrob Agents Chemother. 2014 Jan;58(1):183-95. PMID: 24145526.

Kritsiriwuthinan K, Chaotheing S, Shaw PJ, et al. Global gene expression profiling of Plasmodium falciparum in response to the anti-malarial drug pyronaridine. Malar J. 2011 Aug 18;10:242. PMID: 21849091.

Auparakkitanon S, Chapoomram S, Kuaha K, et al. Targeting of hematin by the antimalarial pyronaridine. Antimicrob Agents Chemother. 2006 Jun;50(6):2197-200. PMID: 16723583.

" Xn Not dangerous goods.

LKT P9768 Pyronaridine Tetraphosphate 1 g 679.5 Hemantin inhibitor. 4-[(7-Chloro-2-methoxybenzo[b]-1,5-naphthyridin-10-yl)amino]-2,6-bis(1-pyrrolidinylmethyl)phenol tetraphosphate Malaridine 76748-86-2 ≥98% 910.03 C29H32ClN5O2 4H3PO4 COC1=CC=C2C(=C(C3=C(N2)C=C(C=C3)Cl)N=C4C=C(C(=O)C(=C4)CN5CCCC5)CN6CCCC6)N1.OP(=O)(O)O.OP(=O)(O)O.OP(=O)(O)O.OP(=O)(O)O Ambient Ambient Soluble in water.  Very sparingly soluble in ethanol. "Henrich PP, O'Brien C, Sáenz FE, et al. Evidence for pyronaridine as a highly effective partner drug for treatment of artemisinin-resistant malaria in a rodent model. Antimicrob Agents Chemother. 2014 Jan;58(1):183-95. PMID: 24145526.

Kritsiriwuthinan K, Chaotheing S, Shaw PJ, et al. Global gene expression profiling of Plasmodium falciparum in response to the anti-malarial drug pyronaridine. Malar J. 2011 Aug 18;10:242. PMID: 21849091.

Auparakkitanon S, Chapoomram S, Kuaha K, et al. Targeting of hematin by the antimalarial pyronaridine. Antimicrob Agents Chemother. 2006 Jun;50(6):2197-200. PMID: 16723583.

" Xn Not dangerous goods.

LKT P0049 Pamidronate Disodium Pentahydrate 10 mg 40.7 Bisphosphonate. (3-Amino-1-hydroxypropylidene)bisphosphonic acid disodium salt pentahydrate Pamidronic acid disodium salt pentahydrate 109552-15-0 ≥98% 369.11 C3H9NNa2O7P2 5H2O C(CN)C(O)(P(=O)(O)[O-])P(=O)(O)[O-].O.O.O.O.O.[Na+].[Na+] Ambient Ambient Soluble in water. "Børsheim E, Herndon DN, Hawkins HK, et al. Pamidronate attenuates muscle loss after pediatric burn injury. J Bone Miner Res. 2014 Jun;29(6):1369-72. PMID: 24347438.

Laroche M, Livideanu C, Paul C, et al. Interferon alpha and pamidronate in osteoporosis with fracture secondary to mastocytosis. Am J Med. 2011 Aug;124(8):776-8. PMID: 21787907.

Kokufu I, Kohno N, Yamamoto M, et al. Adjuvant pamidronate therapy prevents the development of bone metastases in breast cancer patients with four or more positive nodes. Oncol Lett. 2010 Mar;1(2):247-252. PMID: 22966289.

Mawardi H, Giro G, Kajiya M, et al. A role of oral bacteria in bisphosphonate-induced osteonecrosis of the jaw. J Dent Res. 2011 Nov;90(11):1339-1345. PMID: 21921248.

" Xn Not dangerous goods.

LKT P0049 Pamidronate Disodium Pentahydrate 50 mg 133.2 Bisphosphonate. (3-Amino-1-hydroxypropylidene)bisphosphonic acid disodium salt pentahydrate Pamidronic acid disodium salt pentahydrate 109552-15-0 ≥98% 369.11 C3H9NNa2O7P2 5H2O C(CN)C(O)(P(=O)(O)[O-])P(=O)(O)[O-].O.O.O.O.O.[Na+].[Na+] Ambient Ambient Soluble in water. "Børsheim E, Herndon DN, Hawkins HK, et al. Pamidronate attenuates muscle loss after pediatric burn injury. J Bone Miner Res. 2014 Jun;29(6):1369-72. PMID: 24347438.

Laroche M, Livideanu C, Paul C, et al. Interferon alpha and pamidronate in osteoporosis with fracture secondary to mastocytosis. Am J Med. 2011 Aug;124(8):776-8. PMID: 21787907.

Kokufu I, Kohno N, Yamamoto M, et al. Adjuvant pamidronate therapy prevents the development of bone metastases in breast cancer patients with four or more positive nodes. Oncol Lett. 2010 Mar;1(2):247-252. PMID: 22966289.

Mawardi H, Giro G, Kajiya M, et al. A role of oral bacteria in bisphosphonate-induced osteonecrosis of the jaw. J Dent Res. 2011 Nov;90(11):1339-1345. PMID: 21921248.

" Xn Not dangerous goods.

LKT P0049 Pamidronate Disodium Pentahydrate 100 mg 203.8 Bisphosphonate. (3-Amino-1-hydroxypropylidene)bisphosphonic acid disodium salt pentahydrate Pamidronic acid disodium salt pentahydrate 109552-15-0 ≥98% 369.11 C3H9NNa2O7P2 5H2O C(CN)C(O)(P(=O)(O)[O-])P(=O)(O)[O-].O.O.O.O.O.[Na+].[Na+] Ambient Ambient Soluble in water. "Børsheim E, Herndon DN, Hawkins HK, et al. Pamidronate attenuates muscle loss after pediatric burn injury. J Bone Miner Res. 2014 Jun;29(6):1369-72. PMID: 24347438.

Laroche M, Livideanu C, Paul C, et al. Interferon alpha and pamidronate in osteoporosis with fracture secondary to mastocytosis. Am J Med. 2011 Aug;124(8):776-8. PMID: 21787907.

Kokufu I, Kohno N, Yamamoto M, et al. Adjuvant pamidronate therapy prevents the development of bone metastases in breast cancer patients with four or more positive nodes. Oncol Lett. 2010 Mar;1(2):247-252. PMID: 22966289.

Mawardi H, Giro G, Kajiya M, et al. A role of oral bacteria in bisphosphonate-induced osteonecrosis of the jaw. J Dent Res. 2011 Nov;90(11):1339-1345. PMID: 21921248.

" Xn Not dangerous goods.

LKT P9767 Pyriproxyfen 5 g 73.5 Juvenile insect hormone mimic. 2-[1-Methyl-2-(4-phenoxyphenoxy)ethoxy]pyridine Sumilarv 95737-68-1 ≥95% 321.37 C20H19NO3 CC(COC1=CC=C(C=C1)OC2=CC=CC=C2)OC3=CC=CC=N3 Ambient Ambient Soluble in methanol. "Sharmin T, Satho T, Irie K, et al. Pyriproxyfen enhances the immunoglobulin G immune response in mice. Microbiol Immunol. 2013 Apr;57(4):316-22. PMID: 23586635.

Ishaaya I, Kontsedalov S, Horowitz AR. Biorational insecticides: mechanism and cross-resistance. Arch Insect Biochem Physiol. 2005 Apr;58(4):192-9. PMID: 15756702.

Olmstead AW, LeBlanc GA. Insecticidal juvenile hormone analogs stimulate the production of male offspring in the crustacean Daphnia magna. Environ Health Perspect. 2003 Jun;111(7):919-24. PMID: 12782492.

" N Not dangerous goods

LKT P9767 Pyriproxyfen 25 g 209.8 Juvenile insect hormone mimic. 2-[1-Methyl-2-(4-phenoxyphenoxy)ethoxy]pyridine Sumilarv 95737-68-1 ≥95% 321.37 C20H19NO3 CC(COC1=CC=C(C=C1)OC2=CC=CC=C2)OC3=CC=CC=N3 Ambient Ambient Soluble in methanol. "Sharmin T, Satho T, Irie K, et al. Pyriproxyfen enhances the immunoglobulin G immune response in mice. Microbiol Immunol. 2013 Apr;57(4):316-22. PMID: 23586635.

Ishaaya I, Kontsedalov S, Horowitz AR. Biorational insecticides: mechanism and cross-resistance. Arch Insect Biochem Physiol. 2005 Apr;58(4):192-9. PMID: 15756702.

Olmstead AW, LeBlanc GA. Insecticidal juvenile hormone analogs stimulate the production of male offspring in the crustacean Daphnia magna. Environ Health Perspect. 2003 Jun;111(7):919-24. PMID: 12782492.

" N Not dangerous goods

LKT P9767 Pyriproxyfen 100 g 630.1 Juvenile insect hormone mimic. 2-[1-Methyl-2-(4-phenoxyphenoxy)ethoxy]pyridine Sumilarv 95737-68-1 ≥95% 321.37 C20H19NO3 CC(COC1=CC=C(C=C1)OC2=CC=CC=C2)OC3=CC=CC=N3 Ambient Ambient Soluble in methanol. "Sharmin T, Satho T, Irie K, et al. Pyriproxyfen enhances the immunoglobulin G immune response in mice. Microbiol Immunol. 2013 Apr;57(4):316-22. PMID: 23586635.

Ishaaya I, Kontsedalov S, Horowitz AR. Biorational insecticides: mechanism and cross-resistance. Arch Insect Biochem Physiol. 2005 Apr;58(4):192-9. PMID: 15756702.

Olmstead AW, LeBlanc GA. Insecticidal juvenile hormone analogs stimulate the production of male offspring in the crustacean Daphnia magna. Environ Health Perspect. 2003 Jun;111(7):919-24. PMID: 12782492.

" N Not dangerous goods

LKT P0055 P55-TNFR Peptide 1 mg 144 Peptide fragment of  P55 TNF receptor. ≥95% 1342.48 C57H95N15O22 Ambient -20°C "Xanthoulea S, Thelen M, Pöttgens C, et al. Absence of p55 TNF receptor reduces atherosclerosis, but has no major effect on angiotensin II induced aneurysms in LDL receptor deficient mice. PLoS One. 2009 Jul 7;4(7):e6113. PMID: 19582157.

Pandey M, Tuncman G, Hotamisligil GS, et al. Divergent roles for p55 and p75 TNF-alpha receptors in the induction of plasminogen activator inhibitor-1. Am J Pathol. 2003 Mar;162(3):933-41. PMID: 12598326.

Hill GR, Teshima T, Rebel VI, et al. The p55 TNF-alpha receptor plays a critical role in T cell alloreactivity. J Immunol. 2000 Jan 15;164(2):656-63. PMID: 10623807

Uysal KT, Wiesbrock SM, Hotamisligil GS. Functional analysis of tumor necrosis factor (TNF) receptors in TNF-alpha-mediated insulin resistance in genetic obesity. Endocrinology. 1998 Dec;139(12):4832-8. PMID: 9832419.

Shen Y, Li R, Shiosaki K. Inhibition of p75 tumor necrosis factor receptor by antisense oligonucleotides increases hypoxic injury and beta-amyloid toxicity in human neuronal cell line. J Biol Chem. 1997 Feb 7;272(6):3550-3. PMID: 9013604.

"

LKT P0055 P55-TNFR Peptide 2 mg 245.9 Peptide fragment of  P55 TNF receptor. ≥95% 1342.48 C57H95N15O22 Ambient -20°C "Xanthoulea S, Thelen M, Pöttgens C, et al. Absence of p55 TNF receptor reduces atherosclerosis, but has no major effect on angiotensin II induced aneurysms in LDL receptor deficient mice. PLoS One. 2009 Jul 7;4(7):e6113. PMID: 19582157.

Pandey M, Tuncman G, Hotamisligil GS, et al. Divergent roles for p55 and p75 TNF-alpha receptors in the induction of plasminogen activator inhibitor-1. Am J Pathol. 2003 Mar;162(3):933-41. PMID: 12598326.

Hill GR, Teshima T, Rebel VI, et al. The p55 TNF-alpha receptor plays a critical role in T cell alloreactivity. J Immunol. 2000 Jan 15;164(2):656-63. PMID: 10623807

Uysal KT, Wiesbrock SM, Hotamisligil GS. Functional analysis of tumor necrosis factor (TNF) receptors in TNF-alpha-mediated insulin resistance in genetic obesity. Endocrinology. 1998 Dec;139(12):4832-8. PMID: 9832419.

Shen Y, Li R, Shiosaki K. Inhibition of p75 tumor necrosis factor receptor by antisense oligonucleotides increases hypoxic injury and beta-amyloid toxicity in human neuronal cell line. J Biol Chem. 1997 Feb 7;272(6):3550-3. PMID: 9013604.

"

LKT P0055 P55-TNFR Peptide 5 mg 432 Peptide fragment of  P55 TNF receptor. ≥95% 1342.48 C57H95N15O22 Ambient -20°C "Xanthoulea S, Thelen M, Pöttgens C, et al. Absence of p55 TNF receptor reduces atherosclerosis, but has no major effect on angiotensin II induced aneurysms in LDL receptor deficient mice. PLoS One. 2009 Jul 7;4(7):e6113. PMID: 19582157.

Pandey M, Tuncman G, Hotamisligil GS, et al. Divergent roles for p55 and p75 TNF-alpha receptors in the induction of plasminogen activator inhibitor-1. Am J Pathol. 2003 Mar;162(3):933-41. PMID: 12598326.

Hill GR, Teshima T, Rebel VI, et al. The p55 TNF-alpha receptor plays a critical role in T cell alloreactivity. J Immunol. 2000 Jan 15;164(2):656-63. PMID: 10623807

Uysal KT, Wiesbrock SM, Hotamisligil GS. Functional analysis of tumor necrosis factor (TNF) receptors in TNF-alpha-mediated insulin resistance in genetic obesity. Endocrinology. 1998 Dec;139(12):4832-8. PMID: 9832419.

Shen Y, Li R, Shiosaki K. Inhibition of p75 tumor necrosis factor receptor by antisense oligonucleotides increases hypoxic injury and beta-amyloid toxicity in human neuronal cell line. J Biol Chem. 1997 Feb 7;272(6):3550-3. PMID: 9013604.

"

LKT P0075 P75-TNFR Peptide 1 mg 144 Peptide fragment of P75 TNF receptor. ≥95% 1204.42 C53H85N15O15S1 Ambient -20°C "Pandey M, Tuncman G, Hotamisligil GS, et al. Divergent roles for p55 and p75 TNF-alpha receptors in the induction of plasminogen activator inhibitor-1. Am J Pathol. 2003 Mar;162(3):933-41. PMID: 12598326.

Shen Y, Li R, Shiosaki K. Inhibition of p75 tumor necrosis factor receptor by antisense oligonucleotides increases hypoxic injury and beta-amyloid toxicity in human neuronal cell line. J Biol Chem. 1997 Feb 7;272(6):3550-3. PMID: 9013604.

"

LKT P0075 P75-TNFR Peptide 2 mg 245.9 Peptide fragment of P75 TNF receptor. ≥95% 1204.42 C53H85N15O15S1 Ambient -20°C "Pandey M, Tuncman G, Hotamisligil GS, et al. Divergent roles for p55 and p75 TNF-alpha receptors in the induction of plasminogen activator inhibitor-1. Am J Pathol. 2003 Mar;162(3):933-41. PMID: 12598326.

Shen Y, Li R, Shiosaki K. Inhibition of p75 tumor necrosis factor receptor by antisense oligonucleotides increases hypoxic injury and beta-amyloid toxicity in human neuronal cell line. J Biol Chem. 1997 Feb 7;272(6):3550-3. PMID: 9013604.

"

LKT P9671 Pyrazinamide 10 g 40.7 Nicotinamide analog prodrug; fatty acid synthetase I inhibitor. Pyrazinecarboxamide; Pyranzinoic acid amide 98-96-4 ≥98% 123.11 C5H5N3O C1=CN=C(C=N1)C(=O)N Ambient Ambient Soluble in water (15mg/mL). "Singh P, Mishra AK, Malonia SK, et al. The paradox of pyrazinamide: an update on the molecular mechanisms of pyrazinamide resistance in Mycobacteria. J Commun Dis. 2006 Mar;38(3):288-98. PMID: 17373362.

Zhang Y, Wade MM, Scorpio A, et al. Mode of action of pyrazinamide: disruption of Mycobacterium tuberculosis membrane transport and energetics by pyrazinoic acid. J Antimicrob Chemother. 2003 Nov;52(5):790-5. PMID: 14563891.

" None Not dangerous goods.

LKT P0075 P75-TNFR Peptide 5 mg 432 Peptide fragment of P75 TNF receptor. ≥95% 1204.42 C53H85N15O15S1 Ambient -20°C "Pandey M, Tuncman G, Hotamisligil GS, et al. Divergent roles for p55 and p75 TNF-alpha receptors in the induction of plasminogen activator inhibitor-1. Am J Pathol. 2003 Mar;162(3):933-41. PMID: 12598326.

Shen Y, Li R, Shiosaki K. Inhibition of p75 tumor necrosis factor receptor by antisense oligonucleotides increases hypoxic injury and beta-amyloid toxicity in human neuronal cell line. J Biol Chem. 1997 Feb 7;272(6):3550-3. PMID: 9013604.

"

LKT P9671 Pyrazinamide 25 g 67.9 Nicotinamide analog prodrug; fatty acid synthetase I inhibitor. Pyrazinecarboxamide; Pyranzinoic acid amide 98-96-4 ≥98% 123.11 C5H5N3O C1=CN=C(C=N1)C(=O)N Ambient Ambient Soluble in water (15mg/mL). "Singh P, Mishra AK, Malonia SK, et al. The paradox of pyrazinamide: an update on the molecular mechanisms of pyrazinamide resistance in Mycobacteria. J Commun Dis. 2006 Mar;38(3):288-98. PMID: 17373362.

Zhang Y, Wade MM, Scorpio A, et al. Mode of action of pyrazinamide: disruption of Mycobacterium tuberculosis membrane transport and energetics by pyrazinoic acid. J Antimicrob Chemother. 2003 Nov;52(5):790-5. PMID: 14563891.

" None Not dangerous goods.

LKT P9671 Pyrazinamide 100 g 216 Nicotinamide analog prodrug; fatty acid synthetase I inhibitor. Pyrazinecarboxamide; Pyranzinoic acid amide 98-96-4 ≥98% 123.11 C5H5N3O C1=CN=C(C=N1)C(=O)N Ambient Ambient Soluble in water (15mg/mL). "Singh P, Mishra AK, Malonia SK, et al. The paradox of pyrazinamide: an update on the molecular mechanisms of pyrazinamide resistance in Mycobacteria. J Commun Dis. 2006 Mar;38(3):288-98. PMID: 17373362.

Zhang Y, Wade MM, Scorpio A, et al. Mode of action of pyrazinamide: disruption of Mycobacterium tuberculosis membrane transport and energetics by pyrazinoic acid. J Antimicrob Chemother. 2003 Nov;52(5):790-5. PMID: 14563891.

" None Not dangerous goods.

LKT P9668 Pyrantel Pamoate 5 g 33.1 Mixture of pyrantel, a thiophene, and pamoic acid, depolarizing NMJ blocker; nAChR inhibitor. (E)-1,4,5,6-Tetrahydro-1-methyl-2-[2-(2-thienyl)- ethenyl]pyrimidine pamoate Pyrantel embonate; Antiminth; Cobantril; Early bird; Helmex; Piranver 22204-24-6 ≥98% 594.68 C11H14N2S C23H16O6 CN1CCCN=C1C=CC2=CC=CS2.C1=CC=C2C(=C1)C=C(C(=C2CC3=C(C(=CC4=CC=CC=C43)C(=O)O)O)O)C(=O)O Ambient Ambient Insoluble in water. "Reinemeyer CR, Hutchens DE, Eckblad WP, et al. Dose-confirmation studies of the cestocidal activity of pyrantel pamoate paste in horses. Vet Parasitol. 2006 Jun 15;138(3-4):234-9. PMID: 16530970.

Clark JN, Daurio CP, Plue RE, et al. Efficacy of ivermectin and pyrantel pamoate combined in a chewable formulation against heartworm, hookworm, and ascarid infections in dogs. Am J Vet Res. 1992 Apr;53(4):517-20. PMID: 1586021.

" None Not dangerous goods.

LKT P9668 Pyrantel Pamoate 10 g 55 Mixture of pyrantel, a thiophene, and pamoic acid, depolarizing NMJ blocker; nAChR inhibitor. (E)-1,4,5,6-Tetrahydro-1-methyl-2-[2-(2-thienyl)- ethenyl]pyrimidine pamoate Pyrantel embonate; Antiminth; Cobantril; Early bird; Helmex; Piranver 22204-24-6 ≥98% 594.68 C11H14N2S C23H16O6 CN1CCCN=C1C=CC2=CC=CS2.C1=CC=C2C(=C1)C=C(C(=C2CC3=C(C(=CC4=CC=CC=C43)C(=O)O)O)O)C(=O)O Ambient Ambient Insoluble in water. "Reinemeyer CR, Hutchens DE, Eckblad WP, et al. Dose-confirmation studies of the cestocidal activity of pyrantel pamoate paste in horses. Vet Parasitol. 2006 Jun 15;138(3-4):234-9. PMID: 16530970.

Clark JN, Daurio CP, Plue RE, et al. Efficacy of ivermectin and pyrantel pamoate combined in a chewable formulation against heartworm, hookworm, and ascarid infections in dogs. Am J Vet Res. 1992 Apr;53(4):517-20. PMID: 1586021.

" None Not dangerous goods.

LKT P9668 Pyrantel Pamoate 50 g 178.3 Mixture of pyrantel, a thiophene, and pamoic acid, depolarizing NMJ blocker; nAChR inhibitor. (E)-1,4,5,6-Tetrahydro-1-methyl-2-[2-(2-thienyl)- ethenyl]pyrimidine pamoate Pyrantel embonate; Antiminth; Cobantril; Early bird; Helmex; Piranver 22204-24-6 ≥98% 594.68 C11H14N2S C23H16O6 CN1CCCN=C1C=CC2=CC=CS2.C1=CC=C2C(=C1)C=C(C(=C2CC3=C(C(=CC4=CC=CC=C43)C(=O)O)O)O)C(=O)O Ambient Ambient Insoluble in water. "Reinemeyer CR, Hutchens DE, Eckblad WP, et al. Dose-confirmation studies of the cestocidal activity of pyrantel pamoate paste in horses. Vet Parasitol. 2006 Jun 15;138(3-4):234-9. PMID: 16530970.

Clark JN, Daurio CP, Plue RE, et al. Efficacy of ivermectin and pyrantel pamoate combined in a chewable formulation against heartworm, hookworm, and ascarid infections in dogs. Am J Vet Res. 1992 Apr;53(4):517-20. PMID: 1586021.

" None Not dangerous goods.

LKT P8270 Purvalanol A 1 mg 101.1 Purine derivative; CDK inhibitor. 6-[(3-Chloro)anilino]-2(1R)-(isopropyl-2-hydroxyethylamino)-9-isopropylpurine NG-60; Purv 212844-53-6 ≥98% 388.9 C19H25ClN6O CC(C)C(CO)NC1=NC2=C(C(=N1)NC3=CC(=CC=C3)Cl)N=CN2C(C)C Keep cool and dry. Ambient -20°C Soluble in methylene chloride (50mg/mL), DMSO and methanol. "Obakan P, Arısan ED, Özfiliz P, et al. Purvalanol A is a strong apoptotic inducer via activating polyamine catabolic pathway in MCF-7 estrogen receptor positive breast cancer cells. Mol Biol Rep. 2014 Jan;41(1):145-54. PMID: 24190492.

Hofman J, Ahmadimoghaddam D, Hahnova L, et al. Olomoucine II and purvalanol A inhibit ABCG2 transporter in vitro and in situ and synergistically potentiate cytostatic effect of mitoxantrone. Pharmacol Res. 2012 Mar;65(3):312-9. PMID: 22173067.

Park H, Cho JA, Lim EH, et al. Cell cycle regulators are critical for maintaining the differentiation potential and immaturity in adipogenesis of adipose-derived stem cells. Differentiation. 2011 Oct;82(3):136-43. PMID: 21764208.

Iizuka D, Ogura A, Kuwabara M, et al. Purvalanol A induces apoptosis and downregulation of antiapoptotic proteins through abrogation of phosphorylation of JAK2/STAT3 and RNA polymerase II. Anticancer Drugs. 2008 Jul;19(6):565-72. PMID: 18525315.

Agbottah E, Yeh WI, Berro R, et al. Two specific drugs, BMS-345541 and purvalanol A induce apoptosis of HTLV-1 infected cells through inhibition of the NF-kappaB and cell cycle pathways. AIDS Res Ther. 2008 Jun 10;5:12. PMID: 18544167.

" Not dangerous goods.

LKT P8270 Purvalanol A 5 mg 365.2 Purine derivative; CDK inhibitor. 6-[(3-Chloro)anilino]-2(1R)-(isopropyl-2-hydroxyethylamino)-9-isopropylpurine NG-60; Purv 212844-53-6 ≥98% 388.9 C19H25ClN6O CC(C)C(CO)NC1=NC2=C(C(=N1)NC3=CC(=CC=C3)Cl)N=CN2C(C)C Keep cool and dry. Ambient -20°C Soluble in methylene chloride (50mg/mL), DMSO and methanol. "Obakan P, Arısan ED, Özfiliz P, et al. Purvalanol A is a strong apoptotic inducer via activating polyamine catabolic pathway in MCF-7 estrogen receptor positive breast cancer cells. Mol Biol Rep. 2014 Jan;41(1):145-54. PMID: 24190492.

Hofman J, Ahmadimoghaddam D, Hahnova L, et al. Olomoucine II and purvalanol A inhibit ABCG2 transporter in vitro and in situ and synergistically potentiate cytostatic effect of mitoxantrone. Pharmacol Res. 2012 Mar;65(3):312-9. PMID: 22173067.

Park H, Cho JA, Lim EH, et al. Cell cycle regulators are critical for maintaining the differentiation potential and immaturity in adipogenesis of adipose-derived stem cells. Differentiation. 2011 Oct;82(3):136-43. PMID: 21764208.

Iizuka D, Ogura A, Kuwabara M, et al. Purvalanol A induces apoptosis and downregulation of antiapoptotic proteins through abrogation of phosphorylation of JAK2/STAT3 and RNA polymerase II. Anticancer Drugs. 2008 Jul;19(6):565-72. PMID: 18525315.

Agbottah E, Yeh WI, Berro R, et al. Two specific drugs, BMS-345541 and purvalanol A induce apoptosis of HTLV-1 infected cells through inhibition of the NF-kappaB and cell cycle pathways. AIDS Res Ther. 2008 Jun 10;5:12. PMID: 18544167.

" Not dangerous goods.

LKT P0144 Paliperidone 25 mg 84.3 D2 and 5-HT2A antagonist. 3-[2-[4-(6-Fluoro-1,2-benzisoxazol-3-yl)-1-piperidinyl]ethyl]-6,7,8,9-tetrahydro-9-hydroxy-2-methyl-4H-pyrido[1,2-a]pyrimidin-4-one; 9-OH-risperidone 144598-75-4 ≥97% 426.48 C23H27FN4O3 CC1=C(C(=O)N2CCCC(C2=N1)O)CCN3CCC(CC3)C4=NOC5=C4C=CC(=C5)F Ambient Ambient DMSO: >5 mg/mL "Kozielska M, Johnson M, Pilla Reddy V, et al. Pharmacokinetic-pharmacodynamic modeling of the D2 and 5-HT (2A) receptor occupancy of risperidone and paliperidone in rats. Pharm Res. 2012 Jul;29(7):1932-48. PMID: 22437487.

Gilday E, Nasrallah HA. Clinical pharmacology of paliperidone palmitate a parenteral long-acting formulation for the treatment of schizophrenia. Rev Recent Clin Trials. 2012 Feb;7(1):2-9. PMID: 22023179.

De Clerck F, Somers Y, Mannaert E, et al. In vitro effects of risperidone and 9-hydroxy-risperidone on human platelet function, plasma coagulation, and fibrinolysis. Clin Ther. 2004 Aug;26(8):1261-73. PMID: 15476907.

" T "UN number: 2811     Class: 6.1     Packing Group: III

Proper shipping name: Toxic solid, organic, n.o.s. (Paliperidone)"

LKT P0144 Paliperidone 100 mg 240.1 D2 and 5-HT2A antagonist. 3-[2-[4-(6-Fluoro-1,2-benzisoxazol-3-yl)-1-piperidinyl]ethyl]-6,7,8,9-tetrahydro-9-hydroxy-2-methyl-4H-pyrido[1,2-a]pyrimidin-4-one; 9-OH-risperidone 144598-75-4 ≥97% 426.48 C23H27FN4O3 CC1=C(C(=O)N2CCCC(C2=N1)O)CCN3CCC(CC3)C4=NOC5=C4C=CC(=C5)F Ambient Ambient DMSO: >5 mg/mL "Kozielska M, Johnson M, Pilla Reddy V, et al. Pharmacokinetic-pharmacodynamic modeling of the D2 and 5-HT (2A) receptor occupancy of risperidone and paliperidone in rats. Pharm Res. 2012 Jul;29(7):1932-48. PMID: 22437487.

Gilday E, Nasrallah HA. Clinical pharmacology of paliperidone palmitate a parenteral long-acting formulation for the treatment of schizophrenia. Rev Recent Clin Trials. 2012 Feb;7(1):2-9. PMID: 22023179.

De Clerck F, Somers Y, Mannaert E, et al. In vitro effects of risperidone and 9-hydroxy-risperidone on human platelet function, plasma coagulation, and fibrinolysis. Clin Ther. 2004 Aug;26(8):1261-73. PMID: 15476907.

" T "UN number: 2811     Class: 6.1     Packing Group: III

Proper shipping name: Toxic solid, organic, n.o.s. (Paliperidone)"

LKT P0144 Paliperidone 500 mg 960 D2 and 5-HT2A antagonist. 3-[2-[4-(6-Fluoro-1,2-benzisoxazol-3-yl)-1-piperidinyl]ethyl]-6,7,8,9-tetrahydro-9-hydroxy-2-methyl-4H-pyrido[1,2-a]pyrimidin-4-one; 9-OH-risperidone 144598-75-4 ≥97% 426.48 C23H27FN4O3 CC1=C(C(=O)N2CCCC(C2=N1)O)CCN3CCC(CC3)C4=NOC5=C4C=CC(=C5)F Ambient Ambient DMSO: >5 mg/mL "Kozielska M, Johnson M, Pilla Reddy V, et al. Pharmacokinetic-pharmacodynamic modeling of the D2 and 5-HT (2A) receptor occupancy of risperidone and paliperidone in rats. Pharm Res. 2012 Jul;29(7):1932-48. PMID: 22437487.

Gilday E, Nasrallah HA. Clinical pharmacology of paliperidone palmitate a parenteral long-acting formulation for the treatment of schizophrenia. Rev Recent Clin Trials. 2012 Feb;7(1):2-9. PMID: 22023179.

De Clerck F, Somers Y, Mannaert E, et al. In vitro effects of risperidone and 9-hydroxy-risperidone on human platelet function, plasma coagulation, and fibrinolysis. Clin Ther. 2004 Aug;26(8):1261-73. PMID: 15476907.

" T "UN number: 2811     Class: 6.1     Packing Group: III

Proper shipping name: Toxic solid, organic, n.o.s. (Paliperidone)"

LKT P8169 Purpurin 5 g 84.9 Anthraquinone pigment found in madder root; O-acetylpeptidoglycan esterase inhibitor. 1,2,4-Trihydroxy-9,10-anthracenedione Hydroxylizaric acid; Verantin; Purpurine 81-54-9 ≥90% 256.21 C14H8O5 C1=CC=C2C(=C1)C(=O)C3=C(C2=O)C(=C(C=C3O)O)O Ambient Ambient Slightly soluble in water. Soluble in ethanol. "Park H, Shim JS, Kim BS, et al. Purpurin inhibits adipocyte-derived leucine aminopeptidase and angiogenesis in a zebrafish model. Biochem Biophys Res Commun. 2014 Jul 18;450(1):561-7. PMID: 24928393.

Tsang PW, Wong AP, Yang HP, et al. Purpurin triggers caspase-independent apoptosis in Candida dubliniensis biofilms. PLoS One. 2013 Dec 23;8(12):e86032. PMID: 24376900.

Pfeffer JM, Clarke AJ. Identification of the first known inhibitors of O-acetylpeptidoglycan esterase: a potential new antibacterial target. Chembiochem. 2012 Mar 19;13(5):722-31. PMID: 22351512.

Baghiani A, Charef N, Djarmouni M, et al. Free radical scanvenging and antioxidant effects of some anthraquinone derivatives. Med Chem. 2011 Nov;7(6):639-44. PMID: 22313303.

" Xi Not dangerous goods.

LKT P8169 Purpurin 25 g 333.7 Anthraquinone pigment found in madder root; O-acetylpeptidoglycan esterase inhibitor. 1,2,4-Trihydroxy-9,10-anthracenedione Hydroxylizaric acid; Verantin; Purpurine 81-54-9 ≥90% 256.21 C14H8O5 C1=CC=C2C(=C1)C(=O)C3=C(C2=O)C(=C(C=C3O)O)O Ambient Ambient Slightly soluble in water. Soluble in ethanol. "Park H, Shim JS, Kim BS, et al. Purpurin inhibits adipocyte-derived leucine aminopeptidase and angiogenesis in a zebrafish model. Biochem Biophys Res Commun. 2014 Jul 18;450(1):561-7. PMID: 24928393.

Tsang PW, Wong AP, Yang HP, et al. Purpurin triggers caspase-independent apoptosis in Candida dubliniensis biofilms. PLoS One. 2013 Dec 23;8(12):e86032. PMID: 24376900.

Pfeffer JM, Clarke AJ. Identification of the first known inhibitors of O-acetylpeptidoglycan esterase: a potential new antibacterial target. Chembiochem. 2012 Mar 19;13(5):722-31. PMID: 22351512.

Baghiani A, Charef N, Djarmouni M, et al. Free radical scanvenging and antioxidant effects of some anthraquinone derivatives. Med Chem. 2011 Nov;7(6):639-44. PMID: 22313303.

" Xi Not dangerous goods.

LKT P0145 Palmitoyl-D,L-carnitine 100 mg 149.5 Long chain acylcarnitine involved in fatty acid metabolism; PKC inhibitor. Palmitoyl-DL-carnitine chloride 6865-14-1 ≥98% 436.07 C23H46NO4 Cl CCCCCCCCCCCCCCCC(=O)OC(CC(=O)O)C[N+](C)(C)C.[Cl-] Ambient -20°C Soluble in water with heat or sonication. Takahashi T, Kamimura A, Shirai A, et al. Several selective protein kinase C inhibitors including procyanidins promote hair growth. Skin Pharmacol Appl Skin Physiol. 2000 May-Aug;13(3-4):133-42. PMID: 10859531. Xi Not dangerous goods.

LKT P0145 Palmitoyl-D,L-carnitine 500 mg 448.5 Long chain acylcarnitine involved in fatty acid metabolism; PKC inhibitor. Palmitoyl-DL-carnitine chloride 6865-14-1 ≥98% 436.07 C23H46NO4 Cl CCCCCCCCCCCCCCCC(=O)OC(CC(=O)O)C[N+](C)(C)C.[Cl-] Ambient -20°C Soluble in water with heat or sonication. Takahashi T, Kamimura A, Shirai A, et al. Several selective protein kinase C inhibitors including procyanidins promote hair growth. Skin Pharmacol Appl Skin Physiol. 2000 May-Aug;13(3-4):133-42. PMID: 10859531. Xi Not dangerous goods.

LKT P8168 Puromycin Dihydrochloride 10 mg 40.6 Protein synthesis inhibitor, DPP2 and metallopeptidase inhibitor. (3'-[[(2S)-2-Amino-3-(4-methoxyphenyl)-1- oxopropyl]amino]-3'-deoxy-N,N-dimethyl-adenosine Achromycin (before 1953); Stillomycin 58-58-2 ≥98% 544.43 C22H29N7O5 2HCl CN(C)C1=NC=NC2=C1N=CN2C3C(C(C(O3)CO)NC(=O)C(CC4=CC=C(C=C4)OC)N)O Ambient 4°C Soluble in water. "Kang YL, Saleem MA, Chan KW, et al. The cytoprotective role of autophagy in puromycin aminonucleoside treated human podocytes. Biochem Biophys Res Commun. 2014 Jan 10;443(2):628-34. PMID: 24333414.

Liu S, Ding J, Fan Q, et al. The activation of extracellular signal-regulated kinase is responsible for podocyte injury. Mol Biol Rep. 2010 Jun;37(5):2477-84. PMID: 19728154.

Marshall CB, Pippin JW, Krofft RD, et al. Puromycin aminonucleoside induces oxidant-dependent DNA damage in podocytes in vitro and in vivo. Kidney Int. 2006 Dec;70(11):1962-73. PMID: 17035936.

Probst I, Quentmeier A, Schweickhardt C, et al. Stimulation by insulin of glycolysis in cultured hepatocytes is attenuated by extracellular ATP and puromycin through purine-dependent inhibition of phosphofructokinase 2 activation. Eur J Biochem. 1989 Jun 15;182(2):387-93. PMID: 2525468.

" Not dangerous goods.

LKT P8168 Puromycin Dihydrochloride 25 mg 86.4 Protein synthesis inhibitor, DPP2 and metallopeptidase inhibitor. (3'-[[(2S)-2-Amino-3-(4-methoxyphenyl)-1- oxopropyl]amino]-3'-deoxy-N,N-dimethyl-adenosine Achromycin (before 1953); Stillomycin 58-58-2 ≥98% 544.43 C22H29N7O5 2HCl CN(C)C1=NC=NC2=C1N=CN2C3C(C(C(O3)CO)NC(=O)C(CC4=CC=C(C=C4)OC)N)O Ambient 4°C Soluble in water. "Kang YL, Saleem MA, Chan KW, et al. The cytoprotective role of autophagy in puromycin aminonucleoside treated human podocytes. Biochem Biophys Res Commun. 2014 Jan 10;443(2):628-34. PMID: 24333414.

Liu S, Ding J, Fan Q, et al. The activation of extracellular signal-regulated kinase is responsible for podocyte injury. Mol Biol Rep. 2010 Jun;37(5):2477-84. PMID: 19728154.

Marshall CB, Pippin JW, Krofft RD, et al. Puromycin aminonucleoside induces oxidant-dependent DNA damage in podocytes in vitro and in vivo. Kidney Int. 2006 Dec;70(11):1962-73. PMID: 17035936.

Probst I, Quentmeier A, Schweickhardt C, et al. Stimulation by insulin of glycolysis in cultured hepatocytes is attenuated by extracellular ATP and puromycin through purine-dependent inhibition of phosphofructokinase 2 activation. Eur J Biochem. 1989 Jun 15;182(2):387-93. PMID: 2525468.

" Not dangerous goods.

LKT P8168 Puromycin Dihydrochloride 100 mg 294.1 Protein synthesis inhibitor, DPP2 and metallopeptidase inhibitor. (3'-[[(2S)-2-Amino-3-(4-methoxyphenyl)-1- oxopropyl]amino]-3'-deoxy-N,N-dimethyl-adenosine Achromycin (before 1953); Stillomycin 58-58-2 ≥98% 544.43 C22H29N7O5 2HCl CN(C)C1=NC=NC2=C1N=CN2C3C(C(C(O3)CO)NC(=O)C(CC4=CC=C(C=C4)OC)N)O Ambient 4°C Soluble in water. "Kang YL, Saleem MA, Chan KW, et al. The cytoprotective role of autophagy in puromycin aminonucleoside treated human podocytes. Biochem Biophys Res Commun. 2014 Jan 10;443(2):628-34. PMID: 24333414.

Liu S, Ding J, Fan Q, et al. The activation of extracellular signal-regulated kinase is responsible for podocyte injury. Mol Biol Rep. 2010 Jun;37(5):2477-84. PMID: 19728154.

Marshall CB, Pippin JW, Krofft RD, et al. Puromycin aminonucleoside induces oxidant-dependent DNA damage in podocytes in vitro and in vivo. Kidney Int. 2006 Dec;70(11):1962-73. PMID: 17035936.

Probst I, Quentmeier A, Schweickhardt C, et al. Stimulation by insulin of glycolysis in cultured hepatocytes is attenuated by extracellular ATP and puromycin through purine-dependent inhibition of phosphofructokinase 2 activation. Eur J Biochem. 1989 Jun 15;182(2):387-93. PMID: 2525468.

" Not dangerous goods.

LKT P0146 Palmitoyl-L-carnitine 5 mg 125.5 Long chain acylcarnitine involved in fatty acid metabolism; potential sphingosine-1-phosphate agonist. O-Palmitoyl-L-carnitine chloride 18877-64-0 ≥98% 436.1 C23H46NO4 Cl CCCCCCCCCCCCCCCC(=O)OC(CC(=O)O)C[N+](C)(C)C.[Cl-] Ambient -20°C Soluble in water with heat or sonication. "Monternier PA, Marmillot V, Rouanet JL, et al. Mitochondrial phenotypic flexibility enhances energy savings during winter fast in king penguin chicks. J Exp Biol. 2014 Aug 1;217(Pt 15):2691-7. PMID: 24803465.

Bernatoniene J, Majiene D, Peciura R, et al. The effect of Ginkgo biloba extract on mitochondrial oxidative phosphorylation in the normal and ischemic rat heart. Phytother Res. 2011 Jul;25(7):1054-60. PMID: 21259351.

Muraki K, Imaizumi Y. A novel action of palmitoyl-L-carnitine in human vascular endothelial cells. J Pharmacol Sci. 2003 Jul;92(3):252-8. PMID: 12890891.

" Xi Not dangerous goods.

LKT P0146 Palmitoyl-L-carnitine 10 mg 219.3 Long chain acylcarnitine involved in fatty acid metabolism; potential sphingosine-1-phosphate agonist. O-Palmitoyl-L-carnitine chloride 18877-64-0 ≥98% 436.1 C23H46NO4 Cl CCCCCCCCCCCCCCCC(=O)OC(CC(=O)O)C[N+](C)(C)C.[Cl-] Ambient -20°C Soluble in water with heat or sonication. "Monternier PA, Marmillot V, Rouanet JL, et al. Mitochondrial phenotypic flexibility enhances energy savings during winter fast in king penguin chicks. J Exp Biol. 2014 Aug 1;217(Pt 15):2691-7. PMID: 24803465.

Bernatoniene J, Majiene D, Peciura R, et al. The effect of Ginkgo biloba extract on mitochondrial oxidative phosphorylation in the normal and ischemic rat heart. Phytother Res. 2011 Jul;25(7):1054-60. PMID: 21259351.

Muraki K, Imaizumi Y. A novel action of palmitoyl-L-carnitine in human vascular endothelial cells. J Pharmacol Sci. 2003 Jul;92(3):252-8. PMID: 12890891.

" Xi Not dangerous goods.

LKT P8167 Puromycin Aminonucleoside 25 mg 262.6 Purine nucleoside analog; DNA chain terminator, DPP2 and metalloproteinase inhibitor. Stylomycin aminonucleoside 58-60-6 ≥98% 294.31 C12H18N6O3 CN(C)C1=NC=NC2=C1N=CN2C3C(C(C(O3)CO)N)O Ambient 4°C Water "Kang YL, Saleem MA, Chan KW, et al. The cytoprotective role of autophagy in puromycin aminonucleoside treated human podocytes. Biochem Biophys Res Commun. 2014 Jan 10;443(2):628-34. PMID: 24333414.

Liu S, Ding J, Fan Q, et al. The activation of extracellular signal-regulated kinase is responsible for podocyte injury. Mol Biol Rep. 2010 Jun;37(5):2477-84. PMID: 19728154.

Marshall CB, Pippin JW, Krofft RD, et al. Puromycin aminonucleoside induces oxidant-dependent DNA damage in podocytes in vitro and in vivo. Kidney Int. 2006 Dec;70(11):1962-73. PMID: 17035936.

Probst I, Quentmeier A, Schweickhardt C, et al. Stimulation by insulin of glycolysis in cultured hepatocytes is attenuated by extracellular ATP and puromycin through purine-dependent inhibition of phosphofructokinase 2 activation. Eur J Biochem. 1989 Jun 15;182(2):387-93. PMID: 2525468.

" Xi Not dangerous goods.

LKT P8167 Puromycin Aminonucleoside 100 mg 810.1 Purine nucleoside analog; DNA chain terminator, DPP2 and metalloproteinase inhibitor. Stylomycin aminonucleoside 58-60-6 ≥98% 294.31 C12H18N6O3 CN(C)C1=NC=NC2=C1N=CN2C3C(C(C(O3)CO)N)O Ambient 4°C Water "Kang YL, Saleem MA, Chan KW, et al. The cytoprotective role of autophagy in puromycin aminonucleoside treated human podocytes. Biochem Biophys Res Commun. 2014 Jan 10;443(2):628-34. PMID: 24333414.

Liu S, Ding J, Fan Q, et al. The activation of extracellular signal-regulated kinase is responsible for podocyte injury. Mol Biol Rep. 2010 Jun;37(5):2477-84. PMID: 19728154.

Marshall CB, Pippin JW, Krofft RD, et al. Puromycin aminonucleoside induces oxidant-dependent DNA damage in podocytes in vitro and in vivo. Kidney Int. 2006 Dec;70(11):1962-73. PMID: 17035936.

Probst I, Quentmeier A, Schweickhardt C, et al. Stimulation by insulin of glycolysis in cultured hepatocytes is attenuated by extracellular ATP and puromycin through purine-dependent inhibition of phosphofructokinase 2 activation. Eur J Biochem. 1989 Jun 15;182(2):387-93. PMID: 2525468.

" Xi Not dangerous goods.

LKT P0218 Paeoniflorin 1 mg 24.3 Found in Paeonia; L-type Ca2+ channel blocker. Paeonia moutan; Paeony root 23180-57-6 ≥98% 480.46 C23H28O11 CC12CC3(C4CC1(C4(C(O2)O3)COC(=O)C5=CC=CC=C5)OC6C(C(C(C(O6)CO)O)O)O)O Hygroscopic. Ambient -20°C Soluble in water (10 mg/mL)  or ethanol. MeOH 1 mg/mL. "Zhang J, Dou W, Zhang E, et al. Paeoniflorin abrogates DSS-induced colitis via a TLR4-dependent pathway. Am J Physiol Gastrointest Liver Physiol. 2014 Jan 1;306(1):G27-36. PMID: 24232001.

Zhao Y, Zhou G, Wang J, et al. Paeoniflorin protects against ANIT-induced cholestasis by ameliorating oxidative stress in rats. Food Chem Toxicol. 2013 Aug;58:242-8. PMID: 23623840.

Qiu F, Zhong X, Mao Q, et al. The antidepressant-like effects of paeoniflorin in mouse models. Exp Ther Med. 2013 Apr;5(4):1113-1116. PMID: 23599734.

Wang H, Zhou H, Wang CX, et al. Paeoniflorin inhibits growth of human colorectal carcinoma HT 29 cells in vitro and in vivo. Food Chem Toxicol. 2012 May;50(5):1560-7. PMID: 22326807.

Zhang XJ, Li Z, Leung WM, et al. The analgesic effect of paeoniflorin on neonatal maternal separation-induced visceral hyperalgesia in rats. J Pain. 2008 Jun;9(6):497-505. PMID: 18387856.

Tsai TY, Wu SN, Liu YC, et al. Inhibitory action of L-type Ca2+ current by paeoniflorin, a major constituent of peony root, in NG108-15 neuronal cells. Eur J Pharmacol. 2005 Oct 31;523(1-3):16-24. PMID: 16243310.

" None Not dangerous goods.

LKT P0218 Paeoniflorin 5 mg 61.1 Found in Paeonia; L-type Ca2+ channel blocker. Paeonia moutan; Paeony root 23180-57-6 ≥98% 480.46 C23H28O11 CC12CC3(C4CC1(C4(C(O2)O3)COC(=O)C5=CC=CC=C5)OC6C(C(C(C(O6)CO)O)O)O)O Hygroscopic. Ambient -20°C Soluble in water (10 mg/mL)  or ethanol. MeOH 1 mg/mL. "Zhang J, Dou W, Zhang E, et al. Paeoniflorin abrogates DSS-induced colitis via a TLR4-dependent pathway. Am J Physiol Gastrointest Liver Physiol. 2014 Jan 1;306(1):G27-36. PMID: 24232001.

Zhao Y, Zhou G, Wang J, et al. Paeoniflorin protects against ANIT-induced cholestasis by ameliorating oxidative stress in rats. Food Chem Toxicol. 2013 Aug;58:242-8. PMID: 23623840.

Qiu F, Zhong X, Mao Q, et al. The antidepressant-like effects of paeoniflorin in mouse models. Exp Ther Med. 2013 Apr;5(4):1113-1116. PMID: 23599734.

Wang H, Zhou H, Wang CX, et al. Paeoniflorin inhibits growth of human colorectal carcinoma HT 29 cells in vitro and in vivo. Food Chem Toxicol. 2012 May;50(5):1560-7. PMID: 22326807.

Zhang XJ, Li Z, Leung WM, et al. The analgesic effect of paeoniflorin on neonatal maternal separation-induced visceral hyperalgesia in rats. J Pain. 2008 Jun;9(6):497-505. PMID: 18387856.

Tsai TY, Wu SN, Liu YC, et al. Inhibitory action of L-type Ca2+ current by paeoniflorin, a major constituent of peony root, in NG108-15 neuronal cells. Eur J Pharmacol. 2005 Oct 31;523(1-3):16-24. PMID: 16243310.

" None Not dangerous goods.

LKT P0218 Paeoniflorin 10 mg 101.9 Found in Paeonia; L-type Ca2+ channel blocker. Paeonia moutan; Paeony root 23180-57-6 ≥98% 480.46 C23H28O11 CC12CC3(C4CC1(C4(C(O2)O3)COC(=O)C5=CC=CC=C5)OC6C(C(C(C(O6)CO)O)O)O)O Hygroscopic. Ambient -20°C Soluble in water (10 mg/mL)  or ethanol. MeOH 1 mg/mL. "Zhang J, Dou W, Zhang E, et al. Paeoniflorin abrogates DSS-induced colitis via a TLR4-dependent pathway. Am J Physiol Gastrointest Liver Physiol. 2014 Jan 1;306(1):G27-36. PMID: 24232001.

Zhao Y, Zhou G, Wang J, et al. Paeoniflorin protects against ANIT-induced cholestasis by ameliorating oxidative stress in rats. Food Chem Toxicol. 2013 Aug;58:242-8. PMID: 23623840.

Qiu F, Zhong X, Mao Q, et al. The antidepressant-like effects of paeoniflorin in mouse models. Exp Ther Med. 2013 Apr;5(4):1113-1116. PMID: 23599734.

Wang H, Zhou H, Wang CX, et al. Paeoniflorin inhibits growth of human colorectal carcinoma HT 29 cells in vitro and in vivo. Food Chem Toxicol. 2012 May;50(5):1560-7. PMID: 22326807.

Zhang XJ, Li Z, Leung WM, et al. The analgesic effect of paeoniflorin on neonatal maternal separation-induced visceral hyperalgesia in rats. J Pain. 2008 Jun;9(6):497-505. PMID: 18387856.

Tsai TY, Wu SN, Liu YC, et al. Inhibitory action of L-type Ca2+ current by paeoniflorin, a major constituent of peony root, in NG108-15 neuronal cells. Eur J Pharmacol. 2005 Oct 31;523(1-3):16-24. PMID: 16243310.

" None Not dangerous goods.

LKT P8118 Puerarin 100 mg 67.9 Isoflavone daidzein derivative found in Pueraria; GABA-A potentiator, 5-HT2C antagonist. "8-β-D-glucopyranosyl-7-hydroxy-3-

(4-hydroxyphenyl)-(9CI)4H-1-Benzopyran-4-one" 3681-99-0 ≥98% 416.38 C21H20O9 C1=CC(=CC=C1C2=COC3=C(C2=O)C=CC(=C3C4C(C(C(C(O4)CO)O)O)O)O)O Ambient Ambient Soluble in methanol.  Slightly soluble in ethanol. "Liu S, Yu S, Xu C, et al. Puerarin alleviates aggravated sympathoexcitatory response induced by myocardial ischemia via regulating P2X3 receptor in rat superior cervical ganglia. Neurochem Int. 2014 May;70:39-49. PMID: 24657446.

Zhou Y, Xie N, Li L, et al. Puerarin alleviates cognitive impairment and oxidative stress in APP/PS1 transgenic mice. Int J Neuropsychopharmacol. 2014 Apr;17(4):635-44. PMID: 24345484.

Zhang Q, Huang WD, Lv XY, et al. Puerarin protects differentiated PC12 cells from H2O2-induced apoptosis through the PI3K/Akt signalling pathway. Cell Biol Int. 2012 May 1;36(5):419-26. PMID: 22126839.

Overstreet DH, Kralic JE, Morrow AL, et al. NPI-031G (puerarin) reduces anxiogenic effects of alcohol withdrawal or benzodiazepine inverse or 5-HT2C agonists. Pharmacol Biochem Behav. 2003 Jun;75(3):619-25. PMID: 12895679.

" None Not dangerous goods.

LKT P8118 Puerarin 500 mg 183.4 Isoflavone daidzein derivative found in Pueraria; GABA-A potentiator, 5-HT2C antagonist. "8-β-D-glucopyranosyl-7-hydroxy-3-

(4-hydroxyphenyl)-(9CI)4H-1-Benzopyran-4-one" 3681-99-0 ≥98% 416.38 C21H20O9 C1=CC(=CC=C1C2=COC3=C(C2=O)C=CC(=C3C4C(C(C(C(O4)CO)O)O)O)O)O Ambient Ambient Soluble in methanol.  Slightly soluble in ethanol. "Liu S, Yu S, Xu C, et al. Puerarin alleviates aggravated sympathoexcitatory response induced by myocardial ischemia via regulating P2X3 receptor in rat superior cervical ganglia. Neurochem Int. 2014 May;70:39-49. PMID: 24657446.

Zhou Y, Xie N, Li L, et al. Puerarin alleviates cognitive impairment and oxidative stress in APP/PS1 transgenic mice. Int J Neuropsychopharmacol. 2014 Apr;17(4):635-44. PMID: 24345484.

Zhang Q, Huang WD, Lv XY, et al. Puerarin protects differentiated PC12 cells from H2O2-induced apoptosis through the PI3K/Akt signalling pathway. Cell Biol Int. 2012 May 1;36(5):419-26. PMID: 22126839.

Overstreet DH, Kralic JE, Morrow AL, et al. NPI-031G (puerarin) reduces anxiogenic effects of alcohol withdrawal or benzodiazepine inverse or 5-HT2C agonists. Pharmacol Biochem Behav. 2003 Jun;75(3):619-25. PMID: 12895679.

" None Not dangerous goods.

LKT P8118 Puerarin 1 g 237.8 Isoflavone daidzein derivative found in Pueraria; GABA-A potentiator, 5-HT2C antagonist. "8-β-D-glucopyranosyl-7-hydroxy-3-

(4-hydroxyphenyl)-(9CI)4H-1-Benzopyran-4-one" 3681-99-0 ≥98% 416.38 C21H20O9 C1=CC(=CC=C1C2=COC3=C(C2=O)C=CC(=C3C4C(C(C(C(O4)CO)O)O)O)O)O Ambient Ambient Soluble in methanol.  Slightly soluble in ethanol. "Liu S, Yu S, Xu C, et al. Puerarin alleviates aggravated sympathoexcitatory response induced by myocardial ischemia via regulating P2X3 receptor in rat superior cervical ganglia. Neurochem Int. 2014 May;70:39-49. PMID: 24657446.

Zhou Y, Xie N, Li L, et al. Puerarin alleviates cognitive impairment and oxidative stress in APP/PS1 transgenic mice. Int J Neuropsychopharmacol. 2014 Apr;17(4):635-44. PMID: 24345484.

Zhang Q, Huang WD, Lv XY, et al. Puerarin protects differentiated PC12 cells from H2O2-induced apoptosis through the PI3K/Akt signalling pathway. Cell Biol Int. 2012 May 1;36(5):419-26. PMID: 22126839.

Overstreet DH, Kralic JE, Morrow AL, et al. NPI-031G (puerarin) reduces anxiogenic effects of alcohol withdrawal or benzodiazepine inverse or 5-HT2C agonists. Pharmacol Biochem Behav. 2003 Jun;75(3):619-25. PMID: 12895679.

" None Not dangerous goods.

LKT P0219 Paeonol 1 g 27.2 Found in Paeonia, Arisaema, Dioscorea; MAO-A/B inhibitor, voltage-gated and receptor-gated Ca2+ channel blocker. 1-(2-Hydroxy-4-methoxyphenyl)ethanone 4-O-Methylresacetophenone; Resacetophenone-4-methyl ether 552-41-0 ≥98% 166.17 C9H10O3 CC(=O)C1=C(C=C(C=C1)OC)O Ambient Ambient Soluble in water. "Yin J, Wu N, Zeng F, et al. Paeonol induces apoptosis in human ovarian cancer cells. Acta Histochem. 2013 Oct;115(8):835-9. PMID: 23768958.

Wang YQ, Dai M, Zhong JC, et al. Paeonol inhibits oxidized low density lipoprotein-induced monocyte adhesion to vascular endothelial cells by inhibiting the mitogen activated protein kinase pathway. Biol Pharm Bull. 2012;35(5):767-72. PMID: 22687414.

Li YJ, Bao JX, Xu JW, et al. Vascular dilation by paeonol--a mechanism study. Vascul Pharmacol. 2010 Sep-Oct;53(3-4):169-76. PMID: 20643226.

Kim SA, Lee HJ, Ahn KS, et al. Paeonol exerts anti-angiogenic and anti-metastatic activities through downmodulation of Akt activation and inactivation of matrix metalloproteinases. Biol Pharm Bull. 2009 Jul;32(7):1142-7. PMID: 19571375.

Kong LD, Cheng CH, Tan RX. Inhibition of MAO A and B by some plant-derived alkaloids, phenols and anthraquinones. J Ethnopharmacol. 2004 Apr;91(2-3):351-5. PMID: 15120460.

Chou TC. Anti-inflammatory and analgesic effects of paeonol in carrageenan-evoked thermal hyperalgesia. Br J Pharmacol. 2003 Jul;139(6):1146-52. PMID: 12871833.

" Xn Not dangerous goods.

LKT P0219 Paeonol 5 g 88.3 Found in Paeonia, Arisaema, Dioscorea; MAO-A/B inhibitor, voltage-gated and receptor-gated Ca2+ channel blocker. 1-(2-Hydroxy-4-methoxyphenyl)ethanone 4-O-Methylresacetophenone; Resacetophenone-4-methyl ether 552-41-0 ≥98% 166.17 C9H10O3 CC(=O)C1=C(C=C(C=C1)OC)O Ambient Ambient Soluble in water. "Yin J, Wu N, Zeng F, et al. Paeonol induces apoptosis in human ovarian cancer cells. Acta Histochem. 2013 Oct;115(8):835-9. PMID: 23768958.

Wang YQ, Dai M, Zhong JC, et al. Paeonol inhibits oxidized low density lipoprotein-induced monocyte adhesion to vascular endothelial cells by inhibiting the mitogen activated protein kinase pathway. Biol Pharm Bull. 2012;35(5):767-72. PMID: 22687414.

Li YJ, Bao JX, Xu JW, et al. Vascular dilation by paeonol--a mechanism study. Vascul Pharmacol. 2010 Sep-Oct;53(3-4):169-76. PMID: 20643226.

Kim SA, Lee HJ, Ahn KS, et al. Paeonol exerts anti-angiogenic and anti-metastatic activities through downmodulation of Akt activation and inactivation of matrix metalloproteinases. Biol Pharm Bull. 2009 Jul;32(7):1142-7. PMID: 19571375.

Kong LD, Cheng CH, Tan RX. Inhibition of MAO A and B by some plant-derived alkaloids, phenols and anthraquinones. J Ethnopharmacol. 2004 Apr;91(2-3):351-5. PMID: 15120460.

Chou TC. Anti-inflammatory and analgesic effects of paeonol in carrageenan-evoked thermal hyperalgesia. Br J Pharmacol. 2003 Jul;139(6):1146-52. PMID: 12871833.

" Xn Not dangerous goods.

LKT P0245 Palmatine Chloride Hydrate 1 g 40.7 Isoquinoline alkaloid found in Corydalis, Phellodendron, Enantia, binds DNA. 5,6-Dihydro-2,3,9,10-tetramethoxydibenzo[a,g]quinolizinium chloride hydrate Berbericinine; Palmatin 171869-95-7 ≥96% 387.86 C21H22ClNO4 xH2O COC1=C(C2=C[N+]3=C(C=C2C=C1)C4=CC(=C(C=C4CC3)OC)OC)OC.O.[Cl-] Ambient -20°C Soluble in hot water and alcohol. "Hambright HG, Batth IS, Xie J, et al. Palmatine inhibits growth and invasion in prostate cancer cell: Potential role for rpS6/NFκB/FLIP. Mol Carcinog. 2014 Jul 7. [Epub ahead of print]. PMID: 25043857.

Liu B, Yan X, Cao S, et al. Studies on the interaction of palmatine hydrochloride with bovine hemoglobin. Luminescence. 2014 May;29(3):211-8. PMID: 23696111.

Jung J, Choi JS, Jeong CS. Inhibitory Activities of Palmatine from Coptis chinensis Against Helicobactor pylori and Gastric Damage. Toxicol Res. 2014 Mar;30(1):45-8. PMID: 24795799.

Dhingra D, Bhankher A. Behavioral and biochemical evidences for antidepressant-like activity of palmatine in mice subjected to chronic unpredictable mild stress. Pharmacol Rep. 2014 Feb;66(1):1-9. PMID: 24905299.

Bhadra K, Maiti M, Kumar GS. Molecular recognition of DNA by small molecules: AT base pair specific intercalative binding of cytotoxic plant alkaloid palmatine. Biochim Biophys Acta. 2007 Jul;1770(7):1071-80. PMID: 17434677.

Hsieh MT, Su SH, Tsai HY, et al. Effects of palmatine on motor activity and the concentration of central monoamines and its metabolites in rats. Jpn J Pharmacol. 1993 Jan;61(1):1-5. PMID: 7679763.

" Xn "UN number: 2811     Class:  6.1     Packing group:  III

Proper shipping name:  Toxic solids, organic, n.o.s. (Palmatine chloride hydrate)

Marine pollutant:  No / Poison inhalation hazard:  No"

LKT P0245 Palmatine Chloride Hydrate 5 g 122.3 Isoquinoline alkaloid found in Corydalis, Phellodendron, Enantia, binds DNA. 5,6-Dihydro-2,3,9,10-tetramethoxydibenzo[a,g]quinolizinium chloride hydrate Berbericinine; Palmatin 171869-95-7 ≥96% 387.86 C21H22ClNO4 xH2O COC1=C(C2=C[N+]3=C(C=C2C=C1)C4=CC(=C(C=C4CC3)OC)OC)OC.O.[Cl-] Ambient -20°C Soluble in hot water and alcohol. "Hambright HG, Batth IS, Xie J, et al. Palmatine inhibits growth and invasion in prostate cancer cell: Potential role for rpS6/NFκB/FLIP. Mol Carcinog. 2014 Jul 7. [Epub ahead of print]. PMID: 25043857.

Liu B, Yan X, Cao S, et al. Studies on the interaction of palmatine hydrochloride with bovine hemoglobin. Luminescence. 2014 May;29(3):211-8. PMID: 23696111.

Jung J, Choi JS, Jeong CS. Inhibitory Activities of Palmatine from Coptis chinensis Against Helicobactor pylori and Gastric Damage. Toxicol Res. 2014 Mar;30(1):45-8. PMID: 24795799.

Dhingra D, Bhankher A. Behavioral and biochemical evidences for antidepressant-like activity of palmatine in mice subjected to chronic unpredictable mild stress. Pharmacol Rep. 2014 Feb;66(1):1-9. PMID: 24905299.

Bhadra K, Maiti M, Kumar GS. Molecular recognition of DNA by small molecules: AT base pair specific intercalative binding of cytotoxic plant alkaloid palmatine. Biochim Biophys Acta. 2007 Jul;1770(7):1071-80. PMID: 17434677.

Hsieh MT, Su SH, Tsai HY, et al. Effects of palmatine on motor activity and the concentration of central monoamines and its metabolites in rats. Jpn J Pharmacol. 1993 Jan;61(1):1-5. PMID: 7679763.

" Xn "UN number: 2811     Class:  6.1     Packing group:  III

Proper shipping name:  Toxic solids, organic, n.o.s. (Palmatine chloride hydrate)

Marine pollutant:  No / Poison inhalation hazard:  No"

LKT P0245 Palmatine Chloride Hydrate 10 g 169.9 Isoquinoline alkaloid found in Corydalis, Phellodendron, Enantia, binds DNA. 5,6-Dihydro-2,3,9,10-tetramethoxydibenzo[a,g]quinolizinium chloride hydrate Berbericinine; Palmatin 171869-95-7 ≥96% 387.86 C21H22ClNO4 xH2O COC1=C(C2=C[N+]3=C(C=C2C=C1)C4=CC(=C(C=C4CC3)OC)OC)OC.O.[Cl-] Ambient -20°C Soluble in hot water and alcohol. "Hambright HG, Batth IS, Xie J, et al. Palmatine inhibits growth and invasion in prostate cancer cell: Potential role for rpS6/NFκB/FLIP. Mol Carcinog. 2014 Jul 7. [Epub ahead of print]. PMID: 25043857.

Liu B, Yan X, Cao S, et al. Studies on the interaction of palmatine hydrochloride with bovine hemoglobin. Luminescence. 2014 May;29(3):211-8. PMID: 23696111.

Jung J, Choi JS, Jeong CS. Inhibitory Activities of Palmatine from Coptis chinensis Against Helicobactor pylori and Gastric Damage. Toxicol Res. 2014 Mar;30(1):45-8. PMID: 24795799.

Dhingra D, Bhankher A. Behavioral and biochemical evidences for antidepressant-like activity of palmatine in mice subjected to chronic unpredictable mild stress. Pharmacol Rep. 2014 Feb;66(1):1-9. PMID: 24905299.

Bhadra K, Maiti M, Kumar GS. Molecular recognition of DNA by small molecules: AT base pair specific intercalative binding of cytotoxic plant alkaloid palmatine. Biochim Biophys Acta. 2007 Jul;1770(7):1071-80. PMID: 17434677.

Hsieh MT, Su SH, Tsai HY, et al. Effects of palmatine on motor activity and the concentration of central monoamines and its metabolites in rats. Jpn J Pharmacol. 1993 Jan;61(1):1-5. PMID: 7679763.

" Xn "UN number: 2811     Class:  6.1     Packing group:  III

Proper shipping name:  Toxic solids, organic, n.o.s. (Palmatine chloride hydrate)

Marine pollutant:  No / Poison inhalation hazard:  No"

LKT P8117 Puerarin 5 mg 108.8 Isoflavone found in Pueraria; 5-HT2C and GABA-A antagonist. "4H-1-Benzopyran-4-one,8-β-D-glucopyranosyl-7-

hydroxy-3-(4-hydroxyphenyl)-(9CI)" 3681-99-0 ≥98% 416.38 C21H20O9 C1=CC(=CC=C1C2=COC3=C(C2=O)C=CC(=C3C4C(C(C(C(O4)CO)O)O)O)O)O Ambient 4°C Soluble in methanol. "Liu S, Yu S, Xu C, et al. Puerarin alleviates aggravated sympathoexcitatory response induced by myocardial ischemia via regulating P2X3 receptor in rat superior cervical ganglia. Neurochem Int. 2014 May;70:39-49. PMID: 24657446.

Zhou Y, Xie N, Li L, et al. Puerarin alleviates cognitive impairment and oxidative stress in APP/PS1 transgenic mice. Int J Neuropsychopharmacol. 2014 Apr;17(4):635-44. PMID: 24345484.

Zhang Q, Huang WD, Lv XY, et al. Puerarin protects differentiated PC12 cells from H2O2-induced apoptosis through the PI3K/Akt signalling pathway. Cell Biol Int. 2012 May 1;36(5):419-26. PMID: 22126839.

Overstreet DH, Kralic JE, Morrow AL, et al. NPI-031G (puerarin) reduces anxiogenic effects of alcohol withdrawal or benzodiazepine inverse or 5-HT2C agonists. Pharmacol Biochem Behav. 2003 Jun;75(3):619-25. PMID: 12895679.

Malaivijitnond S, Tingmunnuthum D, Gittarasanee S, et al. Puerarin exhibits weak estrogenic activity in female rats. Fitoterapia. 2010 Sep;81(6):569-576. PMID: 20117180.

" None Not dangerous goods.

LKT P8117 Puerarin 10 mg 197.1 Isoflavone found in Pueraria; 5-HT2C and GABA-A antagonist. "4H-1-Benzopyran-4-one,8-β-D-glucopyranosyl-7-

hydroxy-3-(4-hydroxyphenyl)-(9CI)" 3681-99-0 ≥98% 416.38 C21H20O9 C1=CC(=CC=C1C2=COC3=C(C2=O)C=CC(=C3C4C(C(C(C(O4)CO)O)O)O)O)O Ambient 4°C Soluble in methanol. "Liu S, Yu S, Xu C, et al. Puerarin alleviates aggravated sympathoexcitatory response induced by myocardial ischemia via regulating P2X3 receptor in rat superior cervical ganglia. Neurochem Int. 2014 May;70:39-49. PMID: 24657446.

Zhou Y, Xie N, Li L, et al. Puerarin alleviates cognitive impairment and oxidative stress in APP/PS1 transgenic mice. Int J Neuropsychopharmacol. 2014 Apr;17(4):635-44. PMID: 24345484.

Zhang Q, Huang WD, Lv XY, et al. Puerarin protects differentiated PC12 cells from H2O2-induced apoptosis through the PI3K/Akt signalling pathway. Cell Biol Int. 2012 May 1;36(5):419-26. PMID: 22126839.

Overstreet DH, Kralic JE, Morrow AL, et al. NPI-031G (puerarin) reduces anxiogenic effects of alcohol withdrawal or benzodiazepine inverse or 5-HT2C agonists. Pharmacol Biochem Behav. 2003 Jun;75(3):619-25. PMID: 12895679.

Malaivijitnond S, Tingmunnuthum D, Gittarasanee S, et al. Puerarin exhibits weak estrogenic activity in female rats. Fitoterapia. 2010 Sep;81(6):569-576. PMID: 20117180.

" None Not dangerous goods.

LKT P8117 Puerarin 25 mg 407.7 Isoflavone found in Pueraria; 5-HT2C and GABA-A antagonist. "4H-1-Benzopyran-4-one,8-β-D-glucopyranosyl-7-

hydroxy-3-(4-hydroxyphenyl)-(9CI)" 3681-99-0 ≥98% 416.38 C21H20O9 C1=CC(=CC=C1C2=COC3=C(C2=O)C=CC(=C3C4C(C(C(C(O4)CO)O)O)O)O)O Ambient 4°C Soluble in methanol. "Liu S, Yu S, Xu C, et al. Puerarin alleviates aggravated sympathoexcitatory response induced by myocardial ischemia via regulating P2X3 receptor in rat superior cervical ganglia. Neurochem Int. 2014 May;70:39-49. PMID: 24657446.

Zhou Y, Xie N, Li L, et al. Puerarin alleviates cognitive impairment and oxidative stress in APP/PS1 transgenic mice. Int J Neuropsychopharmacol. 2014 Apr;17(4):635-44. PMID: 24345484.

Zhang Q, Huang WD, Lv XY, et al. Puerarin protects differentiated PC12 cells from H2O2-induced apoptosis through the PI3K/Akt signalling pathway. Cell Biol Int. 2012 May 1;36(5):419-26. PMID: 22126839.

Overstreet DH, Kralic JE, Morrow AL, et al. NPI-031G (puerarin) reduces anxiogenic effects of alcohol withdrawal or benzodiazepine inverse or 5-HT2C agonists. Pharmacol Biochem Behav. 2003 Jun;75(3):619-25. PMID: 12895679.

Malaivijitnond S, Tingmunnuthum D, Gittarasanee S, et al. Puerarin exhibits weak estrogenic activity in female rats. Fitoterapia. 2010 Sep;81(6):569-576. PMID: 20117180.

" None Not dangerous goods.

LKT P0252 Pancuronium Bromide 10 mg 65.6 Non-depolarizing NMJ blocker; nAChR antagonist. 1,1'-(3,17-Bis(acetyloxy)androstane-2,16-diyl)bis(1-methylpiperidinium) dibromide 5alpha-Androstan-3alpha, 17beta-diol, 2beta16beta-dipipecolinio-, dibromide, diacetate 15500-66-0 ≥98% 732.67 C35H60Br2N2O4 CC(=O)OC1CC2CCC3C(C2(CC1[N+]4(CCCCC4)C)C)CCC5(C3CC(C5OC(=O)C)[N+]6(CCCCC6)C)C.[Br-].[Br-] Ambient Ambient 0.1 g/ml H2O clear, colorless "

Johnson PN, Miller J, Gormley AK. Continuous-infusion neuromuscular blocking agents in critically ill neonates and children. Pharmacotherapy. 2011 Jun;31(6):609-20. PMID: 21923445.

Jonsson M, Gurley D, Dabrowski M, et al. Distinct pharmacologic properties of neuromuscular blocking agents on human neuronal nicotinic acetylcholine receptors: a possible explanation for the train-of-four fade. Anesthesiology. 2006 Sep;105(3):521-33. PMID: 16931985.

Motamed C, Kirov K, Lieutaud T, et al. The mechanism of pancuronium potentiation of mivacurium block: use of the isolated-arm technique. Anesth Analg. 2000 Sep;91(3):732-5. PMID: 10960409.

" Xn "UN number: 2811     Class: 6.1     Packing Group: III

Proper shipping name: Toxic solid, organic, n.o.s. (Pancuronium bromide)"

LKT P0252 Pancuronium Bromide 50 mg 215.6 Non-depolarizing NMJ blocker; nAChR antagonist. 1,1'-(3,17-Bis(acetyloxy)androstane-2,16-diyl)bis(1-methylpiperidinium) dibromide 5alpha-Androstan-3alpha, 17beta-diol, 2beta16beta-dipipecolinio-, dibromide, diacetate 15500-66-0 ≥98% 732.67 C35H60Br2N2O4 CC(=O)OC1CC2CCC3C(C2(CC1[N+]4(CCCCC4)C)C)CCC5(C3CC(C5OC(=O)C)[N+]6(CCCCC6)C)C.[Br-].[Br-] Ambient Ambient 0.1 g/ml H2O clear, colorless "

Johnson PN, Miller J, Gormley AK. Continuous-infusion neuromuscular blocking agents in critically ill neonates and children. Pharmacotherapy. 2011 Jun;31(6):609-20. PMID: 21923445.

Jonsson M, Gurley D, Dabrowski M, et al. Distinct pharmacologic properties of neuromuscular blocking agents on human neuronal nicotinic acetylcholine receptors: a possible explanation for the train-of-four fade. Anesthesiology. 2006 Sep;105(3):521-33. PMID: 16931985.

Motamed C, Kirov K, Lieutaud T, et al. The mechanism of pancuronium potentiation of mivacurium block: use of the isolated-arm technique. Anesth Analg. 2000 Sep;91(3):732-5. PMID: 10960409.

" Xn "UN number: 2811     Class: 6.1     Packing Group: III

Proper shipping name: Toxic solid, organic, n.o.s. (Pancuronium bromide)"

LKT P0252 Pancuronium Bromide 100 mg 375.1 Non-depolarizing NMJ blocker; nAChR antagonist. 1,1'-(3,17-Bis(acetyloxy)androstane-2,16-diyl)bis(1-methylpiperidinium) dibromide 5alpha-Androstan-3alpha, 17beta-diol, 2beta16beta-dipipecolinio-, dibromide, diacetate 15500-66-0 ≥98% 732.67 C35H60Br2N2O4 CC(=O)OC1CC2CCC3C(C2(CC1[N+]4(CCCCC4)C)C)CCC5(C3CC(C5OC(=O)C)[N+]6(CCCCC6)C)C.[Br-].[Br-] Ambient Ambient 0.1 g/ml H2O clear, colorless "

Johnson PN, Miller J, Gormley AK. Continuous-infusion neuromuscular blocking agents in critically ill neonates and children. Pharmacotherapy. 2011 Jun;31(6):609-20. PMID: 21923445.

Jonsson M, Gurley D, Dabrowski M, et al. Distinct pharmacologic properties of neuromuscular blocking agents on human neuronal nicotinic acetylcholine receptors: a possible explanation for the train-of-four fade. Anesthesiology. 2006 Sep;105(3):521-33. PMID: 16931985.

Motamed C, Kirov K, Lieutaud T, et al. The mechanism of pancuronium potentiation of mivacurium block: use of the isolated-arm technique. Anesth Analg. 2000 Sep;91(3):732-5. PMID: 10960409.

" Xn "UN number: 2811     Class: 6.1     Packing Group: III

Proper shipping name: Toxic solid, organic, n.o.s. (Pancuronium bromide)"

LKT P0252 Pancuronium Bromide 250 mg 703.2 Non-depolarizing NMJ blocker; nAChR antagonist. 1,1'-(3,17-Bis(acetyloxy)androstane-2,16-diyl)bis(1-methylpiperidinium) dibromide 5alpha-Androstan-3alpha, 17beta-diol, 2beta16beta-dipipecolinio-, dibromide, diacetate 15500-66-0 ≥98% 732.67 C35H60Br2N2O4 CC(=O)OC1CC2CCC3C(C2(CC1[N+]4(CCCCC4)C)C)CCC5(C3CC(C5OC(=O)C)[N+]6(CCCCC6)C)C.[Br-].[Br-] Ambient Ambient 0.1 g/ml H2O clear, colorless "

Johnson PN, Miller J, Gormley AK. Continuous-infusion neuromuscular blocking agents in critically ill neonates and children. Pharmacotherapy. 2011 Jun;31(6):609-20. PMID: 21923445.

Jonsson M, Gurley D, Dabrowski M, et al. Distinct pharmacologic properties of neuromuscular blocking agents on human neuronal nicotinic acetylcholine receptors: a possible explanation for the train-of-four fade. Anesthesiology. 2006 Sep;105(3):521-33. PMID: 16931985.

Motamed C, Kirov K, Lieutaud T, et al. The mechanism of pancuronium potentiation of mivacurium block: use of the isolated-arm technique. Anesth Analg. 2000 Sep;91(3):732-5. PMID: 10960409.

" Xn "UN number: 2811     Class: 6.1     Packing Group: III

Proper shipping name: Toxic solid, organic, n.o.s. (Pancuronium bromide)"

LKT P0253 Panaxadiol 5 mg 183 Triterpene sapongenin found in species of Panax; voltage-gated Ca2+ channel blocker. 19666-76-3 ≥98% 460.74 C30H52O3 CC1(CCCC(O1)(C)C2CCC3(C2C(CC4C3(CCC5C4(CCC(C5(C)C)O)C)C)O)C)C Ambient Ambient Soluble in DMSO "Wang Z, Zheng Q, Liu K, et al. Ginsenoside Rh(2) enhances antitumour activity and decreases genotoxic effect of cyclophosphamide. Basic Clin Pharmacol Toxicol. 2006 Apr;98(4):411-5. PMID: 16623867.

Wang ZF, Xiao JS, Yan SZ, et al. Protective effects of panaxadiol saponins on cardiac functions in burned rats. Zhongguo Yao Li Xue Bao. 1995 Jul;16(4):345-8. PMID: 7668107.

Zhang WJ, Zhong GG, Jiang Y, et al. Single channel analysis on calcium channel blockade action of panaxadiol and panaxatriol saponins on cultured rat ventricular myocytes. Zhongguo Yao Li Xue Bao. 1994 Mar;15(2):173-6. PMID: 7516611.

" Not dangerous goods.

LKT P0253 Panaxadiol 10 mg 317.9 Triterpene sapongenin found in species of Panax; voltage-gated Ca2+ channel blocker. 19666-76-3 ≥98% 460.74 C30H52O3 CC1(CCCC(O1)(C)C2CCC3(C2C(CC4C3(CCC5C4(CCC(C5(C)C)O)C)C)O)C)C Ambient Ambient Soluble in DMSO "Wang Z, Zheng Q, Liu K, et al. Ginsenoside Rh(2) enhances antitumour activity and decreases genotoxic effect of cyclophosphamide. Basic Clin Pharmacol Toxicol. 2006 Apr;98(4):411-5. PMID: 16623867.

Wang ZF, Xiao JS, Yan SZ, et al. Protective effects of panaxadiol saponins on cardiac functions in burned rats. Zhongguo Yao Li Xue Bao. 1995 Jul;16(4):345-8. PMID: 7668107.

Zhang WJ, Zhong GG, Jiang Y, et al. Single channel analysis on calcium channel blockade action of panaxadiol and panaxatriol saponins on cultured rat ventricular myocytes. Zhongguo Yao Li Xue Bao. 1994 Mar;15(2):173-6. PMID: 7516611.

" Not dangerous goods.

LKT P0253 Panaxadiol 25 mg 635.4 Triterpene sapongenin found in species of Panax; voltage-gated Ca2+ channel blocker. 19666-76-3 ≥98% 460.74 C30H52O3 CC1(CCCC(O1)(C)C2CCC3(C2C(CC4C3(CCC5C4(CCC(C5(C)C)O)C)C)O)C)C Ambient Ambient Soluble in DMSO "Wang Z, Zheng Q, Liu K, et al. Ginsenoside Rh(2) enhances antitumour activity and decreases genotoxic effect of cyclophosphamide. Basic Clin Pharmacol Toxicol. 2006 Apr;98(4):411-5. PMID: 16623867.

Wang ZF, Xiao JS, Yan SZ, et al. Protective effects of panaxadiol saponins on cardiac functions in burned rats. Zhongguo Yao Li Xue Bao. 1995 Jul;16(4):345-8. PMID: 7668107.

Zhang WJ, Zhong GG, Jiang Y, et al. Single channel analysis on calcium channel blockade action of panaxadiol and panaxatriol saponins on cultured rat ventricular myocytes. Zhongguo Yao Li Xue Bao. 1994 Mar;15(2):173-6. PMID: 7516611.

" Not dangerous goods.

LKT P0254 Panaxatriol 5 mg 183 Triterpene sapogenin found in species of Panax; voltage-gated Ca2+ channel blocker. 32791-84-7 ≥98% 476.73 C30H52O4 CC1(CCCC(O1)(C)C2CCC3(C2C(CC4C3(CC(C5C4(CCC(C5(C)C)O)C)O)C)O)C)C Ambient Ambient Soluble in DMSO. "Huang Y, Yu J, Wan F, et al. Panaxatriol Saponins Attenuated Oxygen-Glucose Deprivation Injury in PC12 Cells via Activation of PI3K/Akt and Nrf2 Signaling Pathway. Oxid Med Cell Longev. 2014;2014:978034. PMID: 24955212.

Wang S, Wang X, Luo F, et al. Panaxatriol saponin ameliorated liver injury by acetaminophen via restoring thioredoxin-1 and pro-caspase-12. Liver Int. 2013 Sep 11. [Epub ahead of print]. PMID: 24119161.

Zhang WJ, Zhong GG, Jiang Y, et al. Single channel analysis on calcium channel blockade action of panaxadiol and panaxatriol saponins on cultured rat ventricular myocytes. Zhongguo Yao Li Xue Bao. 1994 Mar;15(2):173-6. PMID: 7516611.

" Not dangerous goods.

LKT P0254 Panaxatriol 10 mg 317.9 Triterpene sapogenin found in species of Panax; voltage-gated Ca2+ channel blocker. 32791-84-7 ≥98% 476.73 C30H52O4 CC1(CCCC(O1)(C)C2CCC3(C2C(CC4C3(CC(C5C4(CCC(C5(C)C)O)C)O)C)O)C)C Ambient Ambient Soluble in DMSO. "Huang Y, Yu J, Wan F, et al. Panaxatriol Saponins Attenuated Oxygen-Glucose Deprivation Injury in PC12 Cells via Activation of PI3K/Akt and Nrf2 Signaling Pathway. Oxid Med Cell Longev. 2014;2014:978034. PMID: 24955212.

Wang S, Wang X, Luo F, et al. Panaxatriol saponin ameliorated liver injury by acetaminophen via restoring thioredoxin-1 and pro-caspase-12. Liver Int. 2013 Sep 11. [Epub ahead of print]. PMID: 24119161.

Zhang WJ, Zhong GG, Jiang Y, et al. Single channel analysis on calcium channel blockade action of panaxadiol and panaxatriol saponins on cultured rat ventricular myocytes. Zhongguo Yao Li Xue Bao. 1994 Mar;15(2):173-6. PMID: 7516611.

" Not dangerous goods.

LKT P0254 Panaxatriol 25 mg 635.4 Triterpene sapogenin found in species of Panax; voltage-gated Ca2+ channel blocker. 32791-84-7 ≥98% 476.73 C30H52O4 CC1(CCCC(O1)(C)C2CCC3(C2C(CC4C3(CC(C5C4(CCC(C5(C)C)O)C)O)C)O)C)C Ambient Ambient Soluble in DMSO. "Huang Y, Yu J, Wan F, et al. Panaxatriol Saponins Attenuated Oxygen-Glucose Deprivation Injury in PC12 Cells via Activation of PI3K/Akt and Nrf2 Signaling Pathway. Oxid Med Cell Longev. 2014;2014:978034. PMID: 24955212.

Wang S, Wang X, Luo F, et al. Panaxatriol saponin ameliorated liver injury by acetaminophen via restoring thioredoxin-1 and pro-caspase-12. Liver Int. 2013 Sep 11. [Epub ahead of print]. PMID: 24119161.

Zhang WJ, Zhong GG, Jiang Y, et al. Single channel analysis on calcium channel blockade action of panaxadiol and panaxatriol saponins on cultured rat ventricular myocytes. Zhongguo Yao Li Xue Bao. 1994 Mar;15(2):173-6. PMID: 7516611.

" Not dangerous goods.

LKT P0255 Pantoprazole 100 mg 57.8 H+/K+ ATPase and ROCK-2 inhibitor. 5-(Difluoromethoxy)-2-[[(3,4-dimethoxy-2-pyridinyl)- methyl]sulfinyl]-1H-benzimidazole SKF-96022; BY-1023 102625-70-7 ≥98% 383.37 C16H15F2N3O4S COC1=C(C(=NC=C1)CS(=O)C2=NC3=C(N2)C=C(C=C3)OC(F)F)OC Ambient -20°C Soluble in methanol.  Soluble in water (48 mg/ml). "Welsh C, Kasirer MY, Pan J, et al. Pantoprazole decreases gastroesophageal muscle tone in newborn rats via rho-kinase inhibition. Am J Physiol Gastrointest Liver Physiol. 2014 Apr 3. [Epub ahead of print]. PMID: 24699328.

Shea TA, Burburan PJ, Matubia VN, et al. Identification of proton-pump inhibitor drugs that inhibit Trichomonas vaginalis uridine nucleoside ribohydrolase. Bioorg Med Chem Lett. 2014 Feb 15;24(4):1080-4. PMID: 24468412.

Ward RM, Kearns GL. Proton pump inhibitors in pediatrics : mechanism of action, pharmacokinetics, pharmacogenetics, and pharmacodynamics. Paediatr Drugs. 2013 Apr;15(2):119-31. PMID: 23512128.

Vishvakarma NK, Singh SM. Immunopotentiating effect of proton pump inhibitor pantoprazole in a lymphoma-bearing murine host: Implication in antitumor activation of tumor-associated macrophages. Immunol Lett. 2010 Nov 30;134(1):83-92. PMID: 20837061.

" Not dangerous goods.

LKT P0255 Pantoprazole 500 mg 166.5 H+/K+ ATPase and ROCK-2 inhibitor. 5-(Difluoromethoxy)-2-[[(3,4-dimethoxy-2-pyridinyl)- methyl]sulfinyl]-1H-benzimidazole SKF-96022; BY-1023 102625-70-7 ≥98% 383.37 C16H15F2N3O4S COC1=C(C(=NC=C1)CS(=O)C2=NC3=C(N2)C=C(C=C3)OC(F)F)OC Ambient -20°C Soluble in methanol.  Soluble in water (48 mg/ml). "Welsh C, Kasirer MY, Pan J, et al. Pantoprazole decreases gastroesophageal muscle tone in newborn rats via rho-kinase inhibition. Am J Physiol Gastrointest Liver Physiol. 2014 Apr 3. [Epub ahead of print]. PMID: 24699328.

Shea TA, Burburan PJ, Matubia VN, et al. Identification of proton-pump inhibitor drugs that inhibit Trichomonas vaginalis uridine nucleoside ribohydrolase. Bioorg Med Chem Lett. 2014 Feb 15;24(4):1080-4. PMID: 24468412.

Ward RM, Kearns GL. Proton pump inhibitors in pediatrics : mechanism of action, pharmacokinetics, pharmacogenetics, and pharmacodynamics. Paediatr Drugs. 2013 Apr;15(2):119-31. PMID: 23512128.

Vishvakarma NK, Singh SM. Immunopotentiating effect of proton pump inhibitor pantoprazole in a lymphoma-bearing murine host: Implication in antitumor activation of tumor-associated macrophages. Immunol Lett. 2010 Nov 30;134(1):83-92. PMID: 20837061.

" Not dangerous goods.

LKT P0255 Pantoprazole 1 g 277.4 H+/K+ ATPase and ROCK-2 inhibitor. 5-(Difluoromethoxy)-2-[[(3,4-dimethoxy-2-pyridinyl)- methyl]sulfinyl]-1H-benzimidazole SKF-96022; BY-1023 102625-70-7 ≥98% 383.37 C16H15F2N3O4S COC1=C(C(=NC=C1)CS(=O)C2=NC3=C(N2)C=C(C=C3)OC(F)F)OC Ambient -20°C Soluble in methanol.  Soluble in water (48 mg/ml). "Welsh C, Kasirer MY, Pan J, et al. Pantoprazole decreases gastroesophageal muscle tone in newborn rats via rho-kinase inhibition. Am J Physiol Gastrointest Liver Physiol. 2014 Apr 3. [Epub ahead of print]. PMID: 24699328.

Shea TA, Burburan PJ, Matubia VN, et al. Identification of proton-pump inhibitor drugs that inhibit Trichomonas vaginalis uridine nucleoside ribohydrolase. Bioorg Med Chem Lett. 2014 Feb 15;24(4):1080-4. PMID: 24468412.

Ward RM, Kearns GL. Proton pump inhibitors in pediatrics : mechanism of action, pharmacokinetics, pharmacogenetics, and pharmacodynamics. Paediatr Drugs. 2013 Apr;15(2):119-31. PMID: 23512128.

Vishvakarma NK, Singh SM. Immunopotentiating effect of proton pump inhibitor pantoprazole in a lymphoma-bearing murine host: Implication in antitumor activation of tumor-associated macrophages. Immunol Lett. 2010 Nov 30;134(1):83-92. PMID: 20837061.

" Not dangerous goods.

LKT P0260 Papain Inhibitor 5 mg 72.1 Peptide produced in tomato leaves; potential cathepsin and trypsin inhibitor. 70195-20-9 ≥95% 451.49 C19H29N7O6 C1=CC(=CC=C1CC(C(=O)NC(CCCN=C(N)N)C(=O)O)NC(=O)CNC(=O)CN)O Ambient -20°C "Zindel S, Kaman WE, Fröls S, et al. The papain inhibitor (SPI) of Streptomyces mobaraensis inhibits bacterial cysteine proteases and is an antagonist of bacterial growth. Antimicrob Agents Chemother. 2013 Jul;57(7):3388-91. PMID: 23587952.

Bolter CJ. Methyl Jasmonate Induces Papain Inhibitor(s) in Tomato Leaves. Plant Physiol. 1993 Dec;103(4):1347-1353. PMID: 12232028.

Keilová H, Tomásek V. Naturally occurring inhibitors of intracellular proteinases. Acta Biol Med Ger. 1977;36(11-12):1873-81. PMID: 616734.

" Not dangerous goods.

LKT P0260 Papain Inhibitor 10 mg 123.1 Peptide produced in tomato leaves; potential cathepsin and trypsin inhibitor. 70195-20-9 ≥95% 451.49 C19H29N7O6 C1=CC(=CC=C1CC(C(=O)NC(CCCN=C(N)N)C(=O)O)NC(=O)CNC(=O)CN)O Ambient -20°C "Zindel S, Kaman WE, Fröls S, et al. The papain inhibitor (SPI) of Streptomyces mobaraensis inhibits bacterial cysteine proteases and is an antagonist of bacterial growth. Antimicrob Agents Chemother. 2013 Jul;57(7):3388-91. PMID: 23587952.

Bolter CJ. Methyl Jasmonate Induces Papain Inhibitor(s) in Tomato Leaves. Plant Physiol. 1993 Dec;103(4):1347-1353. PMID: 12232028.

Keilová H, Tomásek V. Naturally occurring inhibitors of intracellular proteinases. Acta Biol Med Ger. 1977;36(11-12):1873-81. PMID: 616734.

" Not dangerous goods.

LKT P0260 Papain Inhibitor 25 mg 216.1 Peptide produced in tomato leaves; potential cathepsin and trypsin inhibitor. 70195-20-9 ≥95% 451.49 C19H29N7O6 C1=CC(=CC=C1CC(C(=O)NC(CCCN=C(N)N)C(=O)O)NC(=O)CNC(=O)CN)O Ambient -20°C "Zindel S, Kaman WE, Fröls S, et al. The papain inhibitor (SPI) of Streptomyces mobaraensis inhibits bacterial cysteine proteases and is an antagonist of bacterial growth. Antimicrob Agents Chemother. 2013 Jul;57(7):3388-91. PMID: 23587952.

Bolter CJ. Methyl Jasmonate Induces Papain Inhibitor(s) in Tomato Leaves. Plant Physiol. 1993 Dec;103(4):1347-1353. PMID: 12232028.

Keilová H, Tomásek V. Naturally occurring inhibitors of intracellular proteinases. Acta Biol Med Ger. 1977;36(11-12):1873-81. PMID: 616734.

" Not dangerous goods.

LKT P0268 Parasin I 0.5 mg 228 Histone H2-derived antimicrobial peptide found in Parasilurus. 219552-69-9 ≥95% 2000.36 C82H154N34O24 CC(C)C(C(=O)NC(CCCNC(=N)N)C(=O)NC(C)C(=O)NC(CCCCN)C(=O)NC(C)C(=O)NC(CCCCN)C(=O)NC(C(C)O)C(=O)NC(CCCNC(=N)N)C(=O)NC(CO)C(=O)NC(CO)C(=O)O)NC(=O)C(CCCCN)NC(=O)CNC(=O)CNC(=O)C(CCC(=O)N)NC(=O)C(CCCCN)NC(=O)CNC(=O)C(CCCNC(=N)N)NC(=O)CNC(=O)C(CCCCN)N Ambient -20°C "Koo YS, Kim JM, Park IY, et al. Structure-activity relations of parasin I, a histone H2A-derived antimicrobial peptide. Peptides. 2008 Jul;29(7):1102-8. PMID: 18406495.

Cho JH, Park IY, Kim MS, et al. Matrix metalloproteinase 2 is involved in the regulation of the antimicrobial peptide parasin I production in catfish skin mucosa. FEBS Lett. 2002 Nov 20;531(3):459-63. PMID: 12435593.

Cho JH, Park IY, Kim HS, et al. Cathepsin D produces antimicrobial peptide parasin I from histone H2A in the skin mucosa of fish. FASEB J. 2002 Mar;16(3):429-31. PMID: 11821259.

Park IY, Park CB, Kim MS, et al. Parasin I, an antimicrobial peptide derived from histone H2A in the catfish, Parasilurus asotus. FEBS Lett. 1998 Oct 23;437(3):258-62. PMID: 9824303.

" Not dangerous goods.

LKT P0268 Parasin I 1 mg 387 Histone H2-derived antimicrobial peptide found in Parasilurus. 219552-69-9 ≥95% 2000.36 C82H154N34O24 CC(C)C(C(=O)NC(CCCNC(=N)N)C(=O)NC(C)C(=O)NC(CCCCN)C(=O)NC(C)C(=O)NC(CCCCN)C(=O)NC(C(C)O)C(=O)NC(CCCNC(=N)N)C(=O)NC(CO)C(=O)NC(CO)C(=O)O)NC(=O)C(CCCCN)NC(=O)CNC(=O)CNC(=O)C(CCC(=O)N)NC(=O)C(CCCCN)NC(=O)CNC(=O)C(CCCNC(=N)N)NC(=O)CNC(=O)C(CCCCN)N Ambient -20°C "Koo YS, Kim JM, Park IY, et al. Structure-activity relations of parasin I, a histone H2A-derived antimicrobial peptide. Peptides. 2008 Jul;29(7):1102-8. PMID: 18406495.

Cho JH, Park IY, Kim MS, et al. Matrix metalloproteinase 2 is involved in the regulation of the antimicrobial peptide parasin I production in catfish skin mucosa. FEBS Lett. 2002 Nov 20;531(3):459-63. PMID: 12435593.

Cho JH, Park IY, Kim HS, et al. Cathepsin D produces antimicrobial peptide parasin I from histone H2A in the skin mucosa of fish. FASEB J. 2002 Mar;16(3):429-31. PMID: 11821259.

Park IY, Park CB, Kim MS, et al. Parasin I, an antimicrobial peptide derived from histone H2A in the catfish, Parasilurus asotus. FEBS Lett. 1998 Oct 23;437(3):258-62. PMID: 9824303.

" Not dangerous goods.

LKT P0268 Parasin I 2.5 mg 684.1 Histone H2-derived antimicrobial peptide found in Parasilurus. 219552-69-9 ≥95% 2000.36 C82H154N34O24 CC(C)C(C(=O)NC(CCCNC(=N)N)C(=O)NC(C)C(=O)NC(CCCCN)C(=O)NC(C)C(=O)NC(CCCCN)C(=O)NC(C(C)O)C(=O)NC(CCCNC(=N)N)C(=O)NC(CO)C(=O)NC(CO)C(=O)O)NC(=O)C(CCCCN)NC(=O)CNC(=O)CNC(=O)C(CCC(=O)N)NC(=O)C(CCCCN)NC(=O)CNC(=O)C(CCCNC(=N)N)NC(=O)CNC(=O)C(CCCCN)N Ambient -20°C "Koo YS, Kim JM, Park IY, et al. Structure-activity relations of parasin I, a histone H2A-derived antimicrobial peptide. Peptides. 2008 Jul;29(7):1102-8. PMID: 18406495.

Cho JH, Park IY, Kim MS, et al. Matrix metalloproteinase 2 is involved in the regulation of the antimicrobial peptide parasin I production in catfish skin mucosa. FEBS Lett. 2002 Nov 20;531(3):459-63. PMID: 12435593.

Cho JH, Park IY, Kim HS, et al. Cathepsin D produces antimicrobial peptide parasin I from histone H2A in the skin mucosa of fish. FASEB J. 2002 Mar;16(3):429-31. PMID: 11821259.

Park IY, Park CB, Kim MS, et al. Parasin I, an antimicrobial peptide derived from histone H2A in the catfish, Parasilurus asotus. FEBS Lett. 1998 Oct 23;437(3):258-62. PMID: 9824303.

" Not dangerous goods.

LKT P0269 Parathyroid Hormone (1-34), cow 0.5 mg 300.1 Endogenous peptide hormone, increases extracellular Ca2+ levels; PTH1/2 agonist. Teriparatide 12583-68-5 ≥95% 4108.7 C183H288N54O50S2 "CCC(C)C(C(=O)NC(CCC(=O)N)C(=O)NCC(=O)NC(CCSC)C(=O)NC(Cc1cnc[nH]1)C(=O)NC(CC(=O)N)C(=O)NC(CC(C)C)C(=O)NCC(=O)NC(CCCCN)C(=O)NC(Cc2cnc[nH]2)C(=O)NC(CC(C)C)C(=O)NCC(=O)NC(CO)C(=O)NC(CCSC)C(=O)NC(CCC(=O)O)C(=O)NC(CCCNC(=N)N)C(=O)NC(C(C)C)C(=O)NC(CCC(=O)O)C(=O)NC(Cc3c[nH]c4c3cccc4)C(=O)NC(CC(C)C)C(=O)NC(CCCNC(=N)N)C(=O)NC(CCCCN)C(=O)NC(CCCCN)C(=O)NC(CC(C)C)C(=O)NC(CCC(=O)N)C(=O)NC(CC(=O)O)C(=O)NC(C(C)C)C(=O)NC(Cc5cnc[nH]5)C(=O)NC(CC(=O)N)C(=O)NC(Cc6ccccc6)C(=O)O)NC(=O)C(CCC(=O)O)NC(=O)C(CO)NC(=O)C(C(C)C)NC(=O)CN

" Ambient -20°C Soluble in water. "Ongkeko WM, Burton D, Kiang A, et al. Parathyroid Hormone Related-Protein Promotes Epithelial-to-Mesenchymal Transition in Prostate Cancer. PLoS One. 2014 Jan 22;9(1):e85803. PMID: 24465715.

Augustine M, Horwitz MJ. Parathyroid hormone and parathyroid hormone-related protein analogs as therapies for osteoporosis. Curr Osteoporos Rep. 2013 Dec;11(4):400-6. PMID: 24078470.

Liang FF, Liu CP, Li LX, et al. Activated effects of parathyroid hormone-related protein on human hepatic stellate cells. PLoS One. 2013 Oct 7;8(10):e76517. PMID: 24116114.

Xu J, Rong H, Ji H, et al. Effects of different dosages of parathyroid hormone-related protein 1-34 on the bone metabolism of the ovariectomized rat model of osteoporosis. Calcif Tissue Int. 2013 Sep;93(3):276-87. PMID: 23807531.

Saini V, Marengi DA, Barry KJ, et al. Parathyroid hormone (PTH)/PTH-related peptide type 1 receptor (PPR) signaling in osteocytes regulates anabolic and catabolic skeletal responses to PTH. J Biol Chem. 2013 Jul 12;288(28):20122-34. PMID: 23729679.

Grzesiak JJ, Smith KC, Chalberg C, et al. Heat shock protein-70 expressed on the surface of cancer cells binds parathyroid hormone-related protein in vitro. Endocrinology. 2005 Aug;146(8):3567-76. PMID: 15878959.

Bakre MM, Zhu Y, Yin H, et al. Parathyroid hormone-related peptide is a naturally occurring, protein kinase A-dependent angiogenesis inhibitor. Nat Med. 2002 Sep;8(9):995-1003. PMID: 12185361.

" Not dangerous goods.

LKT P0269 Parathyroid Hormone (1-34), cow 1 mg 510 Endogenous peptide hormone, increases extracellular Ca2+ levels; PTH1/2 agonist. Teriparatide 12583-68-5 ≥95% 4108.7 C183H288N54O50S2 "CCC(C)C(C(=O)NC(CCC(=O)N)C(=O)NCC(=O)NC(CCSC)C(=O)NC(Cc1cnc[nH]1)C(=O)NC(CC(=O)N)C(=O)NC(CC(C)C)C(=O)NCC(=O)NC(CCCCN)C(=O)NC(Cc2cnc[nH]2)C(=O)NC(CC(C)C)C(=O)NCC(=O)NC(CO)C(=O)NC(CCSC)C(=O)NC(CCC(=O)O)C(=O)NC(CCCNC(=N)N)C(=O)NC(C(C)C)C(=O)NC(CCC(=O)O)C(=O)NC(Cc3c[nH]c4c3cccc4)C(=O)NC(CC(C)C)C(=O)NC(CCCNC(=N)N)C(=O)NC(CCCCN)C(=O)NC(CCCCN)C(=O)NC(CC(C)C)C(=O)NC(CCC(=O)N)C(=O)NC(CC(=O)O)C(=O)NC(C(C)C)C(=O)NC(Cc5cnc[nH]5)C(=O)NC(CC(=O)N)C(=O)NC(Cc6ccccc6)C(=O)O)NC(=O)C(CCC(=O)O)NC(=O)C(CO)NC(=O)C(C(C)C)NC(=O)CN

" Ambient -20°C Soluble in water. "Ongkeko WM, Burton D, Kiang A, et al. Parathyroid Hormone Related-Protein Promotes Epithelial-to-Mesenchymal Transition in Prostate Cancer. PLoS One. 2014 Jan 22;9(1):e85803. PMID: 24465715.

Augustine M, Horwitz MJ. Parathyroid hormone and parathyroid hormone-related protein analogs as therapies for osteoporosis. Curr Osteoporos Rep. 2013 Dec;11(4):400-6. PMID: 24078470.

Liang FF, Liu CP, Li LX, et al. Activated effects of parathyroid hormone-related protein on human hepatic stellate cells. PLoS One. 2013 Oct 7;8(10):e76517. PMID: 24116114.

Xu J, Rong H, Ji H, et al. Effects of different dosages of parathyroid hormone-related protein 1-34 on the bone metabolism of the ovariectomized rat model of osteoporosis. Calcif Tissue Int. 2013 Sep;93(3):276-87. PMID: 23807531.

Saini V, Marengi DA, Barry KJ, et al. Parathyroid hormone (PTH)/PTH-related peptide type 1 receptor (PPR) signaling in osteocytes regulates anabolic and catabolic skeletal responses to PTH. J Biol Chem. 2013 Jul 12;288(28):20122-34. PMID: 23729679.

Grzesiak JJ, Smith KC, Chalberg C, et al. Heat shock protein-70 expressed on the surface of cancer cells binds parathyroid hormone-related protein in vitro. Endocrinology. 2005 Aug;146(8):3567-76. PMID: 15878959.

Bakre MM, Zhu Y, Yin H, et al. Parathyroid hormone-related peptide is a naturally occurring, protein kinase A-dependent angiogenesis inhibitor. Nat Med. 2002 Sep;8(9):995-1003. PMID: 12185361.

" Not dangerous goods.

LKT P0269 Parathyroid Hormone (1-34), cow 2.5 mg 900.1 Endogenous peptide hormone, increases extracellular Ca2+ levels; PTH1/2 agonist. Teriparatide 12583-68-5 ≥95% 4108.7 C183H288N54O50S2 "CCC(C)C(C(=O)NC(CCC(=O)N)C(=O)NCC(=O)NC(CCSC)C(=O)NC(Cc1cnc[nH]1)C(=O)NC(CC(=O)N)C(=O)NC(CC(C)C)C(=O)NCC(=O)NC(CCCCN)C(=O)NC(Cc2cnc[nH]2)C(=O)NC(CC(C)C)C(=O)NCC(=O)NC(CO)C(=O)NC(CCSC)C(=O)NC(CCC(=O)O)C(=O)NC(CCCNC(=N)N)C(=O)NC(C(C)C)C(=O)NC(CCC(=O)O)C(=O)NC(Cc3c[nH]c4c3cccc4)C(=O)NC(CC(C)C)C(=O)NC(CCCNC(=N)N)C(=O)NC(CCCCN)C(=O)NC(CCCCN)C(=O)NC(CC(C)C)C(=O)NC(CCC(=O)N)C(=O)NC(CC(=O)O)C(=O)NC(C(C)C)C(=O)NC(Cc5cnc[nH]5)C(=O)NC(CC(=O)N)C(=O)NC(Cc6ccccc6)C(=O)O)NC(=O)C(CCC(=O)O)NC(=O)C(CO)NC(=O)C(C(C)C)NC(=O)CN

" Ambient -20°C Soluble in water. "Ongkeko WM, Burton D, Kiang A, et al. Parathyroid Hormone Related-Protein Promotes Epithelial-to-Mesenchymal Transition in Prostate Cancer. PLoS One. 2014 Jan 22;9(1):e85803. PMID: 24465715.

Augustine M, Horwitz MJ. Parathyroid hormone and parathyroid hormone-related protein analogs as therapies for osteoporosis. Curr Osteoporos Rep. 2013 Dec;11(4):400-6. PMID: 24078470.

Liang FF, Liu CP, Li LX, et al. Activated effects of parathyroid hormone-related protein on human hepatic stellate cells. PLoS One. 2013 Oct 7;8(10):e76517. PMID: 24116114.

Xu J, Rong H, Ji H, et al. Effects of different dosages of parathyroid hormone-related protein 1-34 on the bone metabolism of the ovariectomized rat model of osteoporosis. Calcif Tissue Int. 2013 Sep;93(3):276-87. PMID: 23807531.

Saini V, Marengi DA, Barry KJ, et al. Parathyroid hormone (PTH)/PTH-related peptide type 1 receptor (PPR) signaling in osteocytes regulates anabolic and catabolic skeletal responses to PTH. J Biol Chem. 2013 Jul 12;288(28):20122-34. PMID: 23729679.

Grzesiak JJ, Smith KC, Chalberg C, et al. Heat shock protein-70 expressed on the surface of cancer cells binds parathyroid hormone-related protein in vitro. Endocrinology. 2005 Aug;146(8):3567-76. PMID: 15878959.

Bakre MM, Zhu Y, Yin H, et al. Parathyroid hormone-related peptide is a naturally occurring, protein kinase A-dependent angiogenesis inhibitor. Nat Med. 2002 Sep;8(9):995-1003. PMID: 12185361.

" Not dangerous goods.

LKT P0270 Parthenolide 25 mg 65.6 Sesquiterpene lactone found in Tanacetum; TRPA1 partial agonist, NLRP3 and caspase 1 inhibitor. 20554-84-1 ≥98% 248.32 C15H20O3 CC1=CCCC2(C(O2)C3C(CC1)C(=C)C(=O)O3)C Ambient 4°C DMSO (100 mg/ml), Ethanol (20 mg/ml), Dichloromethane. "Zhao X, Liu X, Su L. Parthenolide induces apoptosis via TNFRSF10B and PMAIP1 pathways in human lung cancer cells. J Exp Clin Cancer Res. 2014 Jan 6;33(1):3. PMID: 24387758.

Materazzi S, Benemei S, Fusi C, et al. Parthenolide inhibits nociception and neurogenic vasodilatation in the trigeminovascular system by targeting the TRPA1 channel. Pain. 2013 Dec;154(12):2750-8. PMID: 23933184.

D'Anneo A, Carlisi D, Lauricella M, et al. Parthenolide generates reactive oxygen species and autophagy in MDA-MB231 cells. A soluble parthenolide analogue inhibits tumour growth and metastasis in a xenograft model of breast cancer. Cell Death Dis. 2013 Oct 31;4:e891. PMID: 24176849.

Juliana C, Fernandes-Alnemri T, Wu J, et al. Anti-inflammatory compounds parthenolide and Bay 11-7082 are direct inhibitors of the inflammasome. J Biol Chem. 2010 Mar 26;285(13):9792-802. PMID: 20093358.

" F, C Not dangerous goods.

LKT P0270 Parthenolide 100 mg 159.4 Sesquiterpene lactone found in Tanacetum; TRPA1 partial agonist, NLRP3 and caspase 1 inhibitor. 20554-84-1 ≥98% 248.32 C15H20O3 CC1=CCCC2(C(O2)C3C(CC1)C(=C)C(=O)O3)C Ambient 4°C DMSO (100 mg/ml), Ethanol (20 mg/ml), Dichloromethane. "Zhao X, Liu X, Su L. Parthenolide induces apoptosis via TNFRSF10B and PMAIP1 pathways in human lung cancer cells. J Exp Clin Cancer Res. 2014 Jan 6;33(1):3. PMID: 24387758.

Materazzi S, Benemei S, Fusi C, et al. Parthenolide inhibits nociception and neurogenic vasodilatation in the trigeminovascular system by targeting the TRPA1 channel. Pain. 2013 Dec;154(12):2750-8. PMID: 23933184.

D'Anneo A, Carlisi D, Lauricella M, et al. Parthenolide generates reactive oxygen species and autophagy in MDA-MB231 cells. A soluble parthenolide analogue inhibits tumour growth and metastasis in a xenograft model of breast cancer. Cell Death Dis. 2013 Oct 31;4:e891. PMID: 24176849.

Juliana C, Fernandes-Alnemri T, Wu J, et al. Anti-inflammatory compounds parthenolide and Bay 11-7082 are direct inhibitors of the inflammasome. J Biol Chem. 2010 Mar 26;285(13):9792-802. PMID: 20093358.

" F, C Not dangerous goods.

LKT P0270 Parthenolide 250 mg 365.7 Sesquiterpene lactone found in Tanacetum; TRPA1 partial agonist, NLRP3 and caspase 1 inhibitor. 20554-84-1 ≥98% 248.32 C15H20O3 CC1=CCCC2(C(O2)C3C(CC1)C(=C)C(=O)O3)C Ambient 4°C DMSO (100 mg/ml), Ethanol (20 mg/ml), Dichloromethane. "Zhao X, Liu X, Su L. Parthenolide induces apoptosis via TNFRSF10B and PMAIP1 pathways in human lung cancer cells. J Exp Clin Cancer Res. 2014 Jan 6;33(1):3. PMID: 24387758.

Materazzi S, Benemei S, Fusi C, et al. Parthenolide inhibits nociception and neurogenic vasodilatation in the trigeminovascular system by targeting the TRPA1 channel. Pain. 2013 Dec;154(12):2750-8. PMID: 23933184.

D'Anneo A, Carlisi D, Lauricella M, et al. Parthenolide generates reactive oxygen species and autophagy in MDA-MB231 cells. A soluble parthenolide analogue inhibits tumour growth and metastasis in a xenograft model of breast cancer. Cell Death Dis. 2013 Oct 31;4:e891. PMID: 24176849.

Juliana C, Fernandes-Alnemri T, Wu J, et al. Anti-inflammatory compounds parthenolide and Bay 11-7082 are direct inhibitors of the inflammasome. J Biol Chem. 2010 Mar 26;285(13):9792-802. PMID: 20093358.

" F, C Not dangerous goods.

LKT P7628 Parathyroid Hormone-Related Protein (1-34), human/rat 0.5 mg 270.2 Endogenous peptide hormone, increases extracellular Ca2+ levels; PTH1 agonist. PTHrP 112540-82-6 ≥95% 4017.65 C180H287N57O48 Ambient -20°C "Ongkeko WM, Burton D, Kiang A, et al. Parathyroid Hormone Related-Protein Promotes Epithelial-to-Mesenchymal Transition in Prostate Cancer. PLoS One. 2014 Jan 22;9(1):e85803. PMID: 24465715.

Augustine M, Horwitz MJ. Parathyroid hormone and parathyroid hormone-related protein analogs as therapies for osteoporosis. Curr Osteoporos Rep. 2013 Dec;11(4):400-6. PMID: 24078470.

Liang FF, Liu CP, Li LX, et al. Activated effects of parathyroid hormone-related protein on human hepatic stellate cells. PLoS One. 2013 Oct 7;8(10):e76517. PMID: 24116114.

Xu J, Rong H, Ji H, et al. Effects of different dosages of parathyroid hormone-related protein 1-34 on the bone metabolism of the ovariectomized rat model of osteoporosis. Calcif Tissue Int. 2013 Sep;93(3):276-87. PMID: 23807531.

Saini V, Marengi DA, Barry KJ, et al. Parathyroid hormone (PTH)/PTH-related peptide type 1 receptor (PPR) signaling in osteocytes regulates anabolic and catabolic skeletal responses to PTH. J Biol Chem. 2013 Jul 12;288(28):20122-34. PMID: 23729679.

Grzesiak JJ, Smith KC, Chalberg C, et al. Heat shock protein-70 expressed on the surface of cancer cells binds parathyroid hormone-related protein in vitro. Endocrinology. 2005 Aug;146(8):3567-76. PMID: 15878959.

Bakre MM, Zhu Y, Yin H, et al. Parathyroid hormone-related peptide is a naturally occurring, protein kinase A-dependent angiogenesis inhibitor. Nat Med. 2002 Sep;8(9):995-1003. PMID: 12185361.

" Not dangerous goods.

LKT P7628 Parathyroid Hormone-Related Protein (1-34), human/rat 1 mg 459.1 Endogenous peptide hormone, increases extracellular Ca2+ levels; PTH1 agonist. PTHrP 112540-82-6 ≥95% 4017.65 C180H287N57O48 Ambient -20°C "Ongkeko WM, Burton D, Kiang A, et al. Parathyroid Hormone Related-Protein Promotes Epithelial-to-Mesenchymal Transition in Prostate Cancer. PLoS One. 2014 Jan 22;9(1):e85803. PMID: 24465715.

Augustine M, Horwitz MJ. Parathyroid hormone and parathyroid hormone-related protein analogs as therapies for osteoporosis. Curr Osteoporos Rep. 2013 Dec;11(4):400-6. PMID: 24078470.

Liang FF, Liu CP, Li LX, et al. Activated effects of parathyroid hormone-related protein on human hepatic stellate cells. PLoS One. 2013 Oct 7;8(10):e76517. PMID: 24116114.

Xu J, Rong H, Ji H, et al. Effects of different dosages of parathyroid hormone-related protein 1-34 on the bone metabolism of the ovariectomized rat model of osteoporosis. Calcif Tissue Int. 2013 Sep;93(3):276-87. PMID: 23807531.

Saini V, Marengi DA, Barry KJ, et al. Parathyroid hormone (PTH)/PTH-related peptide type 1 receptor (PPR) signaling in osteocytes regulates anabolic and catabolic skeletal responses to PTH. J Biol Chem. 2013 Jul 12;288(28):20122-34. PMID: 23729679.

Grzesiak JJ, Smith KC, Chalberg C, et al. Heat shock protein-70 expressed on the surface of cancer cells binds parathyroid hormone-related protein in vitro. Endocrinology. 2005 Aug;146(8):3567-76. PMID: 15878959.

Bakre MM, Zhu Y, Yin H, et al. Parathyroid hormone-related peptide is a naturally occurring, protein kinase A-dependent angiogenesis inhibitor. Nat Med. 2002 Sep;8(9):995-1003. PMID: 12185361.

" Not dangerous goods.

LKT P7628 Parathyroid Hormone-Related Protein (1-34), human/rat 2.5 mg 810.1 Endogenous peptide hormone, increases extracellular Ca2+ levels; PTH1 agonist. PTHrP 112540-82-6 ≥95% 4017.65 C180H287N57O48 Ambient -20°C "Ongkeko WM, Burton D, Kiang A, et al. Parathyroid Hormone Related-Protein Promotes Epithelial-to-Mesenchymal Transition in Prostate Cancer. PLoS One. 2014 Jan 22;9(1):e85803. PMID: 24465715.

Augustine M, Horwitz MJ. Parathyroid hormone and parathyroid hormone-related protein analogs as therapies for osteoporosis. Curr Osteoporos Rep. 2013 Dec;11(4):400-6. PMID: 24078470.

Liang FF, Liu CP, Li LX, et al. Activated effects of parathyroid hormone-related protein on human hepatic stellate cells. PLoS One. 2013 Oct 7;8(10):e76517. PMID: 24116114.

Xu J, Rong H, Ji H, et al. Effects of different dosages of parathyroid hormone-related protein 1-34 on the bone metabolism of the ovariectomized rat model of osteoporosis. Calcif Tissue Int. 2013 Sep;93(3):276-87. PMID: 23807531.

Saini V, Marengi DA, Barry KJ, et al. Parathyroid hormone (PTH)/PTH-related peptide type 1 receptor (PPR) signaling in osteocytes regulates anabolic and catabolic skeletal responses to PTH. J Biol Chem. 2013 Jul 12;288(28):20122-34. PMID: 23729679.

Grzesiak JJ, Smith KC, Chalberg C, et al. Heat shock protein-70 expressed on the surface of cancer cells binds parathyroid hormone-related protein in vitro. Endocrinology. 2005 Aug;146(8):3567-76. PMID: 15878959.

Bakre MM, Zhu Y, Yin H, et al. Parathyroid hormone-related peptide is a naturally occurring, protein kinase A-dependent angiogenesis inhibitor. Nat Med. 2002 Sep;8(9):995-1003. PMID: 12185361.

" Not dangerous goods.

LKT P0278 Patulin 1 mg 41.3 Mycotoxin produced by Penicillum and Aspergillus. 4-Hydroxy-4H-furo[3,2-c]pyran-2(6H)-one Clavacin, clavatin, penicidin 149-29-1 ≥98% 154.12 C7H6O4 C1C=C2C(=CC(=O)O2)C(O1)O Ambient 4°C acetonitrile, ethanol, acetone, ethyl acetate, also soluble in water "Alam S, Pal A, Kumar R, et al. EGFR-mediated Akt and MAPKs signal pathways play a crucial role in patulin-induced cell proliferation in primary murine keratinocytes via modulation of Cyclin D1 and COX-2 expression. Mol Carcinog. 2013 Jun 29. [Epub ahead of print]. PMID: 23813870.

Glaser N, Stopper H. Patulin: Mechanism of genotoxicity. Food Chem Toxicol. 2012 May;50(5):1796-801. PMID: 22425938.

Kwon O, Soung NK, Thimmegowda NR, et al. Patulin induces colorectal cancer cells apoptosis through EGR-1 dependent ATF3 up-regulation. Cell Signal. 2012 Apr;24(4):943-50. PMID: 22230687.

Wu TS, Liao YC, Yu FY, et al. Mechanism of patulin-induced apoptosis in human leukemia cells (HL-60). Toxicol Lett. 2008 Dec 15;183(1-3):105-11. PMID: 18992795.

Mahfoud R, Maresca M, Garmy N, et al. The mycotoxin patulin alters the barrier function of the intestinal epithelium: mechanism of action of the toxin and protective effects of glutathione. Toxicol Appl Pharmacol. 2002 Jun 15;181(3):209-18. PMID: 12079430.

" T, Xi, Xn, Carc. Cat. 3 "UN number: 3462     Class: 6.1     Packing Group: II

Proper shipping name: Toxins, extracted from living sources, solid, n.o.s. (Patulin)"

LKT P0278 Patulin 5 mg 157.5 Mycotoxin produced by Penicillum and Aspergillus. 4-Hydroxy-4H-furo[3,2-c]pyran-2(6H)-one Clavacin, clavatin, penicidin 149-29-1 ≥98% 154.12 C7H6O4 C1C=C2C(=CC(=O)O2)C(O1)O Ambient 4°C acetonitrile, ethanol, acetone, ethyl acetate, also soluble in water "Alam S, Pal A, Kumar R, et al. EGFR-mediated Akt and MAPKs signal pathways play a crucial role in patulin-induced cell proliferation in primary murine keratinocytes via modulation of Cyclin D1 and COX-2 expression. Mol Carcinog. 2013 Jun 29. [Epub ahead of print]. PMID: 23813870.

Glaser N, Stopper H. Patulin: Mechanism of genotoxicity. Food Chem Toxicol. 2012 May;50(5):1796-801. PMID: 22425938.

Kwon O, Soung NK, Thimmegowda NR, et al. Patulin induces colorectal cancer cells apoptosis through EGR-1 dependent ATF3 up-regulation. Cell Signal. 2012 Apr;24(4):943-50. PMID: 22230687.

Wu TS, Liao YC, Yu FY, et al. Mechanism of patulin-induced apoptosis in human leukemia cells (HL-60). Toxicol Lett. 2008 Dec 15;183(1-3):105-11. PMID: 18992795.

Mahfoud R, Maresca M, Garmy N, et al. The mycotoxin patulin alters the barrier function of the intestinal epithelium: mechanism of action of the toxin and protective effects of glutathione. Toxicol Appl Pharmacol. 2002 Jun 15;181(3):209-18. PMID: 12079430.

" T, Xi, Xn, Carc. Cat. 3 "UN number: 3462     Class: 6.1     Packing Group: II

Proper shipping name: Toxins, extracted from living sources, solid, n.o.s. (Patulin)"

LKT P0278 Patulin 10 mg 288.8 Mycotoxin produced by Penicillum and Aspergillus. 4-Hydroxy-4H-furo[3,2-c]pyran-2(6H)-one Clavacin, clavatin, penicidin 149-29-1 ≥98% 154.12 C7H6O4 C1C=C2C(=CC(=O)O2)C(O1)O Ambient 4°C acetonitrile, ethanol, acetone, ethyl acetate, also soluble in water "Alam S, Pal A, Kumar R, et al. EGFR-mediated Akt and MAPKs signal pathways play a crucial role in patulin-induced cell proliferation in primary murine keratinocytes via modulation of Cyclin D1 and COX-2 expression. Mol Carcinog. 2013 Jun 29. [Epub ahead of print]. PMID: 23813870.

Glaser N, Stopper H. Patulin: Mechanism of genotoxicity. Food Chem Toxicol. 2012 May;50(5):1796-801. PMID: 22425938.

Kwon O, Soung NK, Thimmegowda NR, et al. Patulin induces colorectal cancer cells apoptosis through EGR-1 dependent ATF3 up-regulation. Cell Signal. 2012 Apr;24(4):943-50. PMID: 22230687.

Wu TS, Liao YC, Yu FY, et al. Mechanism of patulin-induced apoptosis in human leukemia cells (HL-60). Toxicol Lett. 2008 Dec 15;183(1-3):105-11. PMID: 18992795.

Mahfoud R, Maresca M, Garmy N, et al. The mycotoxin patulin alters the barrier function of the intestinal epithelium: mechanism of action of the toxin and protective effects of glutathione. Toxicol Appl Pharmacol. 2002 Jun 15;181(3):209-18. PMID: 12079430.

" T, Xi, Xn, Carc. Cat. 3 "UN number: 3462     Class: 6.1     Packing Group: II

Proper shipping name: Toxins, extracted from living sources, solid, n.o.s. (Patulin)"

LKT P7359 Psoralidin 10 mg 117.1 Phenol found in Psoralea coryfolia. 3,9-Dihydroxy-2-(3-methyl-2-butenyl)-6H-benzofuro[3,2-c][1]benzopyran-6-one 6-(3-methylbut-2-enyl)coumestrol 18642-23-4 ≥98% 336.34 C20H16O5 CC(=CCC1=C(C=C2C(=C1)C3=C(C4=C(O3)C=C(C=C4)O)C(=O)O2)O)C Ambient Ambient "Suman S, Das TP, Damodaran C. Silencing NOTCH signaling causes growth arrest in both breast cancer stem cells and breast cancer cells. Br J Cancer. 2013 Nov 12;109(10):2587-96. PMID: 24129237.

Chopra B, Dhingra AK, Dhar KL. Psoralea corylifolia L. (Buguchi) - folklore to modern evidence: review. Fitoterapia. 2013 Oct;90:44-56. PMID: 23831482.

Chiou WF, Don MJ, Liao JF, et al. Psoralidin inhibits LPS-induced iNOS expression via repressing Syk-mediated activation of PI3K-IKK-IκB signaling pathways. Eur J Pharmacol. 2011 Jan 10;650(1):102-9. PMID: 20951127.

Kumar R, Srinivasan S, Pahari P, et al. Activating stress-activated protein kinase-mediated cell death and inhibiting epidermal growth factor receptor signaling: a promising therapeutic strategy for prostate cancer. Mol Cancer Ther. 2010 Sep;9(9):2488-96. PMID: 20736346.

Lee SJ, Nam KW, Mar W. Induction of quinone reductase activity by psoralidin isolated from Psoralea corylifolia in mouse hepa 1c1c7 cells. Arch Pharm Res. 2009 Jul;32(7):1061-5. PMID: 19641888.

Yi LT, Li YC, Pan Y, et al. Antidepressant-like effects of psoralidin isolated from the seeds of Psoralea Corylifolia in the forced swimming test in mice. Prog Neuropsychopharmacol Biol Psychiatry. 2008 Feb 15;32(2):510-9. PMID: 18006202.

Khatune NA, Islam ME, Haque ME, et al. Antibacterial compounds from the seeds of Psoralea corylifolia. Fitoterapia. 2004 Mar;75(2):228-30. PMID: 15030932.

" Not dangerous goods.

LKT P7359 Psoralidin 25 mg 234.5 Phenol found in Psoralea coryfolia. 3,9-Dihydroxy-2-(3-methyl-2-butenyl)-6H-benzofuro[3,2-c][1]benzopyran-6-one 6-(3-methylbut-2-enyl)coumestrol 18642-23-4 ≥98% 336.34 C20H16O5 CC(=CCC1=C(C=C2C(=C1)C3=C(C4=C(O3)C=C(C=C4)O)C(=O)O2)O)C Ambient Ambient "Suman S, Das TP, Damodaran C. Silencing NOTCH signaling causes growth arrest in both breast cancer stem cells and breast cancer cells. Br J Cancer. 2013 Nov 12;109(10):2587-96. PMID: 24129237.

Chopra B, Dhingra AK, Dhar KL. Psoralea corylifolia L. (Buguchi) - folklore to modern evidence: review. Fitoterapia. 2013 Oct;90:44-56. PMID: 23831482.

Chiou WF, Don MJ, Liao JF, et al. Psoralidin inhibits LPS-induced iNOS expression via repressing Syk-mediated activation of PI3K-IKK-IκB signaling pathways. Eur J Pharmacol. 2011 Jan 10;650(1):102-9. PMID: 20951127.

Kumar R, Srinivasan S, Pahari P, et al. Activating stress-activated protein kinase-mediated cell death and inhibiting epidermal growth factor receptor signaling: a promising therapeutic strategy for prostate cancer. Mol Cancer Ther. 2010 Sep;9(9):2488-96. PMID: 20736346.

Lee SJ, Nam KW, Mar W. Induction of quinone reductase activity by psoralidin isolated from Psoralea corylifolia in mouse hepa 1c1c7 cells. Arch Pharm Res. 2009 Jul;32(7):1061-5. PMID: 19641888.

Yi LT, Li YC, Pan Y, et al. Antidepressant-like effects of psoralidin isolated from the seeds of Psoralea Corylifolia in the forced swimming test in mice. Prog Neuropsychopharmacol Biol Psychiatry. 2008 Feb 15;32(2):510-9. PMID: 18006202.

Khatune NA, Islam ME, Haque ME, et al. Antibacterial compounds from the seeds of Psoralea corylifolia. Fitoterapia. 2004 Mar;75(2):228-30. PMID: 15030932.

" Not dangerous goods.

LKT P7359 Psoralidin 100 mg 669.7 Phenol found in Psoralea coryfolia. 3,9-Dihydroxy-2-(3-methyl-2-butenyl)-6H-benzofuro[3,2-c][1]benzopyran-6-one 6-(3-methylbut-2-enyl)coumestrol 18642-23-4 ≥98% 336.34 C20H16O5 CC(=CCC1=C(C=C2C(=C1)C3=C(C4=C(O3)C=C(C=C4)O)C(=O)O2)O)C Ambient Ambient "Suman S, Das TP, Damodaran C. Silencing NOTCH signaling causes growth arrest in both breast cancer stem cells and breast cancer cells. Br J Cancer. 2013 Nov 12;109(10):2587-96. PMID: 24129237.

Chopra B, Dhingra AK, Dhar KL. Psoralea corylifolia L. (Buguchi) - folklore to modern evidence: review. Fitoterapia. 2013 Oct;90:44-56. PMID: 23831482.

Chiou WF, Don MJ, Liao JF, et al. Psoralidin inhibits LPS-induced iNOS expression via repressing Syk-mediated activation of PI3K-IKK-IκB signaling pathways. Eur J Pharmacol. 2011 Jan 10;650(1):102-9. PMID: 20951127.

Kumar R, Srinivasan S, Pahari P, et al. Activating stress-activated protein kinase-mediated cell death and inhibiting epidermal growth factor receptor signaling: a promising therapeutic strategy for prostate cancer. Mol Cancer Ther. 2010 Sep;9(9):2488-96. PMID: 20736346.

Lee SJ, Nam KW, Mar W. Induction of quinone reductase activity by psoralidin isolated from Psoralea corylifolia in mouse hepa 1c1c7 cells. Arch Pharm Res. 2009 Jul;32(7):1061-5. PMID: 19641888.

Yi LT, Li YC, Pan Y, et al. Antidepressant-like effects of psoralidin isolated from the seeds of Psoralea Corylifolia in the forced swimming test in mice. Prog Neuropsychopharmacol Biol Psychiatry. 2008 Feb 15;32(2):510-9. PMID: 18006202.

Khatune NA, Islam ME, Haque ME, et al. Antibacterial compounds from the seeds of Psoralea corylifolia. Fitoterapia. 2004 Mar;75(2):228-30. PMID: 15030932.

" Not dangerous goods.

LKT P7358 Psoralen 10 mg 92.1 Furanocoumarin found in Psoralea coryfolia, DNA cross-linker; topoisomerase I inhibitor. Ficusin 66-97-7 ≥98% 186.16 C11H6O3 C1=CC(=O)OC2=CC3=C(C=CO3)C=C21 Ambient Ambient Soluble in ethanol (10 mg/ml), ethyl acetate, acetone, and water (1.93 mg/ml at 25 °C). "Chopra B, Dhingra AK, Dhar KL. Psoralea corylifolia L. (Buguchi) - folklore to modern evidence: review. Fitoterapia. 2013 Oct;90:44-56. PMID: 23831482.

Diwan R, Malpathak N. Furanocoumarins: novel topoisomerase I inhibitors from Ruta graveolens L. Bioorg Med Chem. 2009 Oct 1;17(19):7052-5. PMID: 19736019.

Derheimer FA, Hicks JK, Paulsen MT, et al. Psoralen-induced DNA interstrand cross-links block transcription and induce p53 in an ataxia-telangiectasia and rad3-related-dependent manner. Mol Pharmacol. 2009 Mar;75(3):599-607. PMID: 19064630.

Deng H, Yan CL, Hu Y, et al. Photochemotherapy inhibits angiogenesis and induces apoptosis of endothelial cells in vitro. Photodermatol Photoimmunol Photomed. 2004 Aug;20(4):191-9. PMID: 15238097.

" Xi Not dangerous goods.

LKT P7358 Psoralen 25 mg 184.2 Furanocoumarin found in Psoralea coryfolia, DNA cross-linker; topoisomerase I inhibitor. Ficusin 66-97-7 ≥98% 186.16 C11H6O3 C1=CC(=O)OC2=CC3=C(C=CO3)C=C21 Ambient Ambient Soluble in ethanol (10 mg/ml), ethyl acetate, acetone, and water (1.93 mg/ml at 25 °C). "Chopra B, Dhingra AK, Dhar KL. Psoralea corylifolia L. (Buguchi) - folklore to modern evidence: review. Fitoterapia. 2013 Oct;90:44-56. PMID: 23831482.

Diwan R, Malpathak N. Furanocoumarins: novel topoisomerase I inhibitors from Ruta graveolens L. Bioorg Med Chem. 2009 Oct 1;17(19):7052-5. PMID: 19736019.

Derheimer FA, Hicks JK, Paulsen MT, et al. Psoralen-induced DNA interstrand cross-links block transcription and induce p53 in an ataxia-telangiectasia and rad3-related-dependent manner. Mol Pharmacol. 2009 Mar;75(3):599-607. PMID: 19064630.

Deng H, Yan CL, Hu Y, et al. Photochemotherapy inhibits angiogenesis and induces apoptosis of endothelial cells in vitro. Photodermatol Photoimmunol Photomed. 2004 Aug;20(4):191-9. PMID: 15238097.

" Xi Not dangerous goods.

LKT P7358 Psoralen 100 mg 502.3 Furanocoumarin found in Psoralea coryfolia, DNA cross-linker; topoisomerase I inhibitor. Ficusin 66-97-7 ≥98% 186.16 C11H6O3 C1=CC(=O)OC2=CC3=C(C=CO3)C=C21 Ambient Ambient Soluble in ethanol (10 mg/ml), ethyl acetate, acetone, and water (1.93 mg/ml at 25 °C). "Chopra B, Dhingra AK, Dhar KL. Psoralea corylifolia L. (Buguchi) - folklore to modern evidence: review. Fitoterapia. 2013 Oct;90:44-56. PMID: 23831482.

Diwan R, Malpathak N. Furanocoumarins: novel topoisomerase I inhibitors from Ruta graveolens L. Bioorg Med Chem. 2009 Oct 1;17(19):7052-5. PMID: 19736019.

Derheimer FA, Hicks JK, Paulsen MT, et al. Psoralen-induced DNA interstrand cross-links block transcription and induce p53 in an ataxia-telangiectasia and rad3-related-dependent manner. Mol Pharmacol. 2009 Mar;75(3):599-607. PMID: 19064630.

Deng H, Yan CL, Hu Y, et al. Photochemotherapy inhibits angiogenesis and induces apoptosis of endothelial cells in vitro. Photodermatol Photoimmunol Photomed. 2004 Aug;20(4):191-9. PMID: 15238097.

" Xi Not dangerous goods.

LKT P0297 Paroxetine Hydrochloride Hemihydrate 100 mg 193.5 FIASMA, SERT and NET inhibitor, mAChR antagonist. (3S-trans)-3-[(1,3-Benzodioxol-5-yloxy)methyl]-4-(4- fluorophenyl)piperidine hydrochloride hemihydrate Paroxetine hydrochloride hemihydrate; Paxil: Aropax; Deroxat; Seroxat 110429-35-1 ≥98% 374.84 C19H20FNO3 HCl 1/2H2O C1CNCC(C1C2=CC=C(C=C2)F)COC3=CC4=C(C=C3)OCO4 Ambient Ambient Soluble in water (5.4 mg/mL), DMSO(73 mg/mL), and ethanol (35mg/mL) "Liu RP, Zou M, Wang JY, et al. Paroxetine ameliorates lipopolysaccharide-induced microglia activation via differential regulation of MAPK signaling. J Neuroinflammation. 2014 Mar 12;11:47. PMID: 24618100.

Aboukhatwa M, Luo Y. Antidepressants modulate intracellular amyloid peptide species in N2a neuroblastoma cells. J Alzheimers Dis. 2011;24(2):221-34. PMID: 21263193.

Young TJ, Oliver GP, Pryde D, et al. Antifungal activity of selective serotonin reuptake inhibitors attributed to non-specific cytotoxicity. J Antimicrob Chemother. 2003 Apr;51(4):1045-7. PMID: 12654745.

Munoz-Bellido JL, Munoz-Criado S, Garcìa-Rodrìguez JA. Antimicrobial activity of psychotropic drugs: selective serotonin reuptake inhibitors. Int J Antimicrob Agents. 2000 Apr;14(3):177-80. PMID: 10773485.

" Xn Not dangerous goods.

LKT P0297 Paroxetine Hydrochloride Hemihydrate 500 mg 711.5 FIASMA, SERT and NET inhibitor, mAChR antagonist. (3S-trans)-3-[(1,3-Benzodioxol-5-yloxy)methyl]-4-(4- fluorophenyl)piperidine hydrochloride hemihydrate Paroxetine hydrochloride hemihydrate; Paxil: Aropax; Deroxat; Seroxat 110429-35-1 ≥98% 374.84 C19H20FNO3 HCl 1/2H2O C1CNCC(C1C2=CC=C(C=C2)F)COC3=CC4=C(C=C3)OCO4 Ambient Ambient Soluble in water (5.4 mg/mL), DMSO(73 mg/mL), and ethanol (35mg/mL) "Liu RP, Zou M, Wang JY, et al. Paroxetine ameliorates lipopolysaccharide-induced microglia activation via differential regulation of MAPK signaling. J Neuroinflammation. 2014 Mar 12;11:47. PMID: 24618100.

Aboukhatwa M, Luo Y. Antidepressants modulate intracellular amyloid peptide species in N2a neuroblastoma cells. J Alzheimers Dis. 2011;24(2):221-34. PMID: 21263193.

Young TJ, Oliver GP, Pryde D, et al. Antifungal activity of selective serotonin reuptake inhibitors attributed to non-specific cytotoxicity. J Antimicrob Chemother. 2003 Apr;51(4):1045-7. PMID: 12654745.

Munoz-Bellido JL, Munoz-Criado S, Garcìa-Rodrìguez JA. Antimicrobial activity of psychotropic drugs: selective serotonin reuptake inhibitors. Int J Antimicrob Agents. 2000 Apr;14(3):177-80. PMID: 10773485.

" Xn Not dangerous goods.

LKT P0297 Paroxetine Hydrochloride Hemihydrate 1 g 1232.9 FIASMA, SERT and NET inhibitor, mAChR antagonist. (3S-trans)-3-[(1,3-Benzodioxol-5-yloxy)methyl]-4-(4- fluorophenyl)piperidine hydrochloride hemihydrate Paroxetine hydrochloride hemihydrate; Paxil: Aropax; Deroxat; Seroxat 110429-35-1 ≥98% 374.84 C19H20FNO3 HCl 1/2H2O C1CNCC(C1C2=CC=C(C=C2)F)COC3=CC4=C(C=C3)OCO4 Ambient Ambient Soluble in water (5.4 mg/mL), DMSO(73 mg/mL), and ethanol (35mg/mL) "Liu RP, Zou M, Wang JY, et al. Paroxetine ameliorates lipopolysaccharide-induced microglia activation via differential regulation of MAPK signaling. J Neuroinflammation. 2014 Mar 12;11:47. PMID: 24618100.

Aboukhatwa M, Luo Y. Antidepressants modulate intracellular amyloid peptide species in N2a neuroblastoma cells. J Alzheimers Dis. 2011;24(2):221-34. PMID: 21263193.

Young TJ, Oliver GP, Pryde D, et al. Antifungal activity of selective serotonin reuptake inhibitors attributed to non-specific cytotoxicity. J Antimicrob Chemother. 2003 Apr;51(4):1045-7. PMID: 12654745.

Munoz-Bellido JL, Munoz-Criado S, Garcìa-Rodrìguez JA. Antimicrobial activity of psychotropic drugs: selective serotonin reuptake inhibitors. Int J Antimicrob Agents. 2000 Apr;14(3):177-80. PMID: 10773485.

" Xn Not dangerous goods.

LKT P7318 Pseudoginsenoside F11 5 mg 163.2 Saponin found in species of Panax; PPARγ agonist. 69884-00-0 ≥98% 801.49 C42H72O14 CC1CC2(C3CC(C4C(CCC4(C3CC(C2C(C1O)(C)C)OC5C(C(C(C(O5)CO)O)O)OC6C(C(C(C(O6)C)O)O)O)C)C7(CCC(O7)C(C)(C)O)C)O)C Ambient 4°C "Wang X, Wang C, Wang J, et al. Pseudoginsenoside-F11 (PF11) exerts anti-neuroinflammatory effects on LPS-activated microglial cells by inhibiting TLR4-mediated TAK1/IKK/NF-κB, MAPKs and Akt signaling pathways. Neuropharmacology. 2014 Apr;79:642-56. PMID: 24467851.

Wu G, Yi J, Liu L, et al. Pseudoginsenoside F11, a Novel Partial PPAR γ Agonist, Promotes Adiponectin Oligomerization and Secretion in 3T3-L1 Adipocytes. PPAR Res. 2013;2013:701017. PMID: 24454336.

Wang JY, Yang JY, Wang F, et al. Neuroprotective effect of pseudoginsenoside-f11 on a rat model of Parkinson's disease induced by 6-hydroxydopamine. Evid Based Complement Alternat Med. 2013;2013:152798. PMID: 24386001.

Wang CM, Liu MY, Wang F, et al. Anti-amnesic effect of pseudoginsenoside-F11 in two mouse models of Alzheimer's disease. Pharmacol Biochem Behav. 2013 May;106:57-67. PMID: 23541491.

" Xn Not dangerous goods.

LKT P7318 Pseudoginsenoside F11 10 mg 231 Saponin found in species of Panax; PPARγ agonist. 69884-00-0 ≥98% 801.49 C42H72O14 CC1CC2(C3CC(C4C(CCC4(C3CC(C2C(C1O)(C)C)OC5C(C(C(C(O5)CO)O)O)OC6C(C(C(C(O6)C)O)O)O)C)C7(CCC(O7)C(C)(C)O)C)O)C Ambient 4°C "Wang X, Wang C, Wang J, et al. Pseudoginsenoside-F11 (PF11) exerts anti-neuroinflammatory effects on LPS-activated microglial cells by inhibiting TLR4-mediated TAK1/IKK/NF-κB, MAPKs and Akt signaling pathways. Neuropharmacology. 2014 Apr;79:642-56. PMID: 24467851.

Wu G, Yi J, Liu L, et al. Pseudoginsenoside F11, a Novel Partial PPAR γ Agonist, Promotes Adiponectin Oligomerization and Secretion in 3T3-L1 Adipocytes. PPAR Res. 2013;2013:701017. PMID: 24454336.

Wang JY, Yang JY, Wang F, et al. Neuroprotective effect of pseudoginsenoside-f11 on a rat model of Parkinson's disease induced by 6-hydroxydopamine. Evid Based Complement Alternat Med. 2013;2013:152798. PMID: 24386001.

Wang CM, Liu MY, Wang F, et al. Anti-amnesic effect of pseudoginsenoside-F11 in two mouse models of Alzheimer's disease. Pharmacol Biochem Behav. 2013 May;106:57-67. PMID: 23541491.

" Xn Not dangerous goods.

LKT P7318 Pseudoginsenoside F11 25 mg 475.7 Saponin found in species of Panax; PPARγ agonist. 69884-00-0 ≥98% 801.49 C42H72O14 CC1CC2(C3CC(C4C(CCC4(C3CC(C2C(C1O)(C)C)OC5C(C(C(C(O5)CO)O)O)OC6C(C(C(C(O6)C)O)O)O)C)C7(CCC(O7)C(C)(C)O)C)O)C Ambient 4°C "Wang X, Wang C, Wang J, et al. Pseudoginsenoside-F11 (PF11) exerts anti-neuroinflammatory effects on LPS-activated microglial cells by inhibiting TLR4-mediated TAK1/IKK/NF-κB, MAPKs and Akt signaling pathways. Neuropharmacology. 2014 Apr;79:642-56. PMID: 24467851.

Wu G, Yi J, Liu L, et al. Pseudoginsenoside F11, a Novel Partial PPAR γ Agonist, Promotes Adiponectin Oligomerization and Secretion in 3T3-L1 Adipocytes. PPAR Res. 2013;2013:701017. PMID: 24454336.

Wang JY, Yang JY, Wang F, et al. Neuroprotective effect of pseudoginsenoside-f11 on a rat model of Parkinson's disease induced by 6-hydroxydopamine. Evid Based Complement Alternat Med. 2013;2013:152798. PMID: 24386001.

Wang CM, Liu MY, Wang F, et al. Anti-amnesic effect of pseudoginsenoside-F11 in two mouse models of Alzheimer's disease. Pharmacol Biochem Behav. 2013 May;106:57-67. PMID: 23541491.

" Xn Not dangerous goods.

LKT P0350 Pancreatic Polypeptide, chicken 0.5 mg 276.2 Endogenous peptide, regulates pancreatic cell signaling; Y4 agonist. 58591-52-9 ≥95% 4237.69 C190H283N53O58 CCC(C)C(C(=O)NC(CCCNC(=N)N)C(=O)NC(CC1=CC=CC=C1)C(=O)NC(CC2=CC=C(C=C2)O)C(=O)NC(CC(=O)O)C(=O)NC(CC(=O)N)C(=O)NC(CC(C)C)C(=O)NC(CCC(=O)N)C(=O)NC(CCC(=O)N)C(=O)NC(CC3=CC=C(C=C3)O)C(=O)NC(CC(C)C)C(=O)NC(CC(=O)N)C(=O)NC(C(C)C)C(=O)NC(C(C)C)C(=O)NC(C(C)O)C(=O)NC(CCCNC(=N)N)C(=O)NC(CC4=CN=CN4)C(=O)NC(CCCNC(=N)N)C(=O)NC(CC5=CC=C(C=C5)O)C(=O)N)NC(=O)C(CC(C)C)NC(=O)C(CC(=O)O)NC(=O)C(CCC(=O)O)NC(=O)C(C(C)C)NC(=O)C6CCCN6C(=O)C(C)NC(=O)C(CC(=O)O)NC(=O)C(CC(=O)O)NC(=O)CNC(=O)C7CCCN7C(=O)C(CC8=CC=C(C=C8)O)NC(=O)C(C(C)O)NC(=O)C9CCCN9C(=O)C(CCC(=O)N)NC(=O)C(CO)NC(=O)C1CCCN1C(=O)CN Ambient -20°C "Kahleova H, Mari A, Nofrate V, et al. Improvement in β-cell function after diet-induced weight loss is associated with decrease in pancreatic polypeptide in subjects with type 2 diabetes. J Diabetes Complications. 2012 Sep-Oct;26(5):442-9. PMID: 22673566.

Hankir MK, Parkinson JR, Minnion JS, et al. Peptide YY 3-36 and pancreatic polypeptide differentially regulate hypothalamic neuronal activity in mice in vivo as measured by manganese-enhanced magnetic resonance imaging. J Neuroendocrinol. 2011 Apr;23(4):371-80. PMID: 21251093.

Moriya R, Fujikawa T, Ito J, et al. Pancreatic polypeptide enhances colonic muscle contraction and fecal output through neuropeptide Y Y4 receptor in mice. Eur J Pharmacol. 2010 Feb 10;627(1-3):258-64. PMID: 19818748.

Liu YL, Semjonous NM, Murphy KG, et al. The effects of pancreatic polypeptide on locomotor activity and food intake in mice. Int J Obes (Lond). 2008 Nov;32(11):1712-5. PMID: 18779824.

" Not dangerous goods.

LKT P7103 Praziquantel 1 g 33.9 Alters membrane permeability and Ca2+ signaling; potential adenosine antagonist, potential voltage-gated Ca2+ channel blocker. "2-(Cyclohexylcarbonyl)-1,2,3,6,7-11b-hexahydro-4H-

pyrazino[2,1-a]isoquinolin-4-one" Biltricide; Cesol; Droncit 55268-74-1 ≥98% 312.41 C19H24N2O2 C1CCC(CC1)C(=O)N2CC3C4=CC=CC=C4CCN3C(=O)C2 Ambient Ambient Soluble in ethanol or chloroform. "Cioli D, Pica-Mattoccia L, Basso A, et al. Schistosomiasis control: praziquantel forever? Mol Biochem Parasitol. 2014 Jun 21;195(1):23-29. PMID: 24955523.

Chan JD, Zarowiecki M, Marchant JS. Ca2+ channels and praziquantel: a view from the free world. Parasitol Int. 2013 Dec;62(6):619-28. PMID: 23246536.

Crosby A, Jones FM, Kolosionek E, et al. Praziquantel reverses pulmonary hypertension and vascular remodeling in murine schistosomiasis. Am J Respir Crit Care Med. 2011 Aug 15;184(4):467-73. PMID: 21659614.

" None Not dangerous goods.

LKT P0350 Pancreatic Polypeptide, chicken 1 mg 468.2 Endogenous peptide, regulates pancreatic cell signaling; Y4 agonist. 58591-52-9 ≥95% 4237.69 C190H283N53O58 CCC(C)C(C(=O)NC(CCCNC(=N)N)C(=O)NC(CC1=CC=CC=C1)C(=O)NC(CC2=CC=C(C=C2)O)C(=O)NC(CC(=O)O)C(=O)NC(CC(=O)N)C(=O)NC(CC(C)C)C(=O)NC(CCC(=O)N)C(=O)NC(CCC(=O)N)C(=O)NC(CC3=CC=C(C=C3)O)C(=O)NC(CC(C)C)C(=O)NC(CC(=O)N)C(=O)NC(C(C)C)C(=O)NC(C(C)C)C(=O)NC(C(C)O)C(=O)NC(CCCNC(=N)N)C(=O)NC(CC4=CN=CN4)C(=O)NC(CCCNC(=N)N)C(=O)NC(CC5=CC=C(C=C5)O)C(=O)N)NC(=O)C(CC(C)C)NC(=O)C(CC(=O)O)NC(=O)C(CCC(=O)O)NC(=O)C(C(C)C)NC(=O)C6CCCN6C(=O)C(C)NC(=O)C(CC(=O)O)NC(=O)C(CC(=O)O)NC(=O)CNC(=O)C7CCCN7C(=O)C(CC8=CC=C(C=C8)O)NC(=O)C(C(C)O)NC(=O)C9CCCN9C(=O)C(CCC(=O)N)NC(=O)C(CO)NC(=O)C1CCCN1C(=O)CN Ambient -20°C "Kahleova H, Mari A, Nofrate V, et al. Improvement in β-cell function after diet-induced weight loss is associated with decrease in pancreatic polypeptide in subjects with type 2 diabetes. J Diabetes Complications. 2012 Sep-Oct;26(5):442-9. PMID: 22673566.

Hankir MK, Parkinson JR, Minnion JS, et al. Peptide YY 3-36 and pancreatic polypeptide differentially regulate hypothalamic neuronal activity in mice in vivo as measured by manganese-enhanced magnetic resonance imaging. J Neuroendocrinol. 2011 Apr;23(4):371-80. PMID: 21251093.

Moriya R, Fujikawa T, Ito J, et al. Pancreatic polypeptide enhances colonic muscle contraction and fecal output through neuropeptide Y Y4 receptor in mice. Eur J Pharmacol. 2010 Feb 10;627(1-3):258-64. PMID: 19818748.

Liu YL, Semjonous NM, Murphy KG, et al. The effects of pancreatic polypeptide on locomotor activity and food intake in mice. Int J Obes (Lond). 2008 Nov;32(11):1712-5. PMID: 18779824.

" Not dangerous goods.

LKT P0350 Pancreatic Polypeptide, chicken 2.5 mg 828.1 Endogenous peptide, regulates pancreatic cell signaling; Y4 agonist. 58591-52-9 ≥95% 4237.69 C190H283N53O58 CCC(C)C(C(=O)NC(CCCNC(=N)N)C(=O)NC(CC1=CC=CC=C1)C(=O)NC(CC2=CC=C(C=C2)O)C(=O)NC(CC(=O)O)C(=O)NC(CC(=O)N)C(=O)NC(CC(C)C)C(=O)NC(CCC(=O)N)C(=O)NC(CCC(=O)N)C(=O)NC(CC3=CC=C(C=C3)O)C(=O)NC(CC(C)C)C(=O)NC(CC(=O)N)C(=O)NC(C(C)C)C(=O)NC(C(C)C)C(=O)NC(C(C)O)C(=O)NC(CCCNC(=N)N)C(=O)NC(CC4=CN=CN4)C(=O)NC(CCCNC(=N)N)C(=O)NC(CC5=CC=C(C=C5)O)C(=O)N)NC(=O)C(CC(C)C)NC(=O)C(CC(=O)O)NC(=O)C(CCC(=O)O)NC(=O)C(C(C)C)NC(=O)C6CCCN6C(=O)C(C)NC(=O)C(CC(=O)O)NC(=O)C(CC(=O)O)NC(=O)CNC(=O)C7CCCN7C(=O)C(CC8=CC=C(C=C8)O)NC(=O)C(C(C)O)NC(=O)C9CCCN9C(=O)C(CCC(=O)N)NC(=O)C(CO)NC(=O)C1CCCN1C(=O)CN Ambient -20°C "Kahleova H, Mari A, Nofrate V, et al. Improvement in β-cell function after diet-induced weight loss is associated with decrease in pancreatic polypeptide in subjects with type 2 diabetes. J Diabetes Complications. 2012 Sep-Oct;26(5):442-9. PMID: 22673566.

Hankir MK, Parkinson JR, Minnion JS, et al. Peptide YY 3-36 and pancreatic polypeptide differentially regulate hypothalamic neuronal activity in mice in vivo as measured by manganese-enhanced magnetic resonance imaging. J Neuroendocrinol. 2011 Apr;23(4):371-80. PMID: 21251093.

Moriya R, Fujikawa T, Ito J, et al. Pancreatic polypeptide enhances colonic muscle contraction and fecal output through neuropeptide Y Y4 receptor in mice. Eur J Pharmacol. 2010 Feb 10;627(1-3):258-64. PMID: 19818748.

Liu YL, Semjonous NM, Murphy KG, et al. The effects of pancreatic polypeptide on locomotor activity and food intake in mice. Int J Obes (Lond). 2008 Nov;32(11):1712-5. PMID: 18779824.

" Not dangerous goods.

LKT P7103 Praziquantel 5 g 40.7 Alters membrane permeability and Ca2+ signaling; potential adenosine antagonist, potential voltage-gated Ca2+ channel blocker. "2-(Cyclohexylcarbonyl)-1,2,3,6,7-11b-hexahydro-4H-

pyrazino[2,1-a]isoquinolin-4-one" Biltricide; Cesol; Droncit 55268-74-1 ≥98% 312.41 C19H24N2O2 C1CCC(CC1)C(=O)N2CC3C4=CC=CC=C4CCN3C(=O)C2 Ambient Ambient Soluble in ethanol or chloroform. "Cioli D, Pica-Mattoccia L, Basso A, et al. Schistosomiasis control: praziquantel forever? Mol Biochem Parasitol. 2014 Jun 21;195(1):23-29. PMID: 24955523.

Chan JD, Zarowiecki M, Marchant JS. Ca2+ channels and praziquantel: a view from the free world. Parasitol Int. 2013 Dec;62(6):619-28. PMID: 23246536.

Crosby A, Jones FM, Kolosionek E, et al. Praziquantel reverses pulmonary hypertension and vascular remodeling in murine schistosomiasis. Am J Respir Crit Care Med. 2011 Aug 15;184(4):467-73. PMID: 21659614.

" None Not dangerous goods.

LKT P7103 Praziquantel 25 g 163.2 Alters membrane permeability and Ca2+ signaling; potential adenosine antagonist, potential voltage-gated Ca2+ channel blocker. "2-(Cyclohexylcarbonyl)-1,2,3,6,7-11b-hexahydro-4H-

pyrazino[2,1-a]isoquinolin-4-one" Biltricide; Cesol; Droncit 55268-74-1 ≥98% 312.41 C19H24N2O2 C1CCC(CC1)C(=O)N2CC3C4=CC=CC=C4CCN3C(=O)C2 Ambient Ambient Soluble in ethanol or chloroform. "Cioli D, Pica-Mattoccia L, Basso A, et al. Schistosomiasis control: praziquantel forever? Mol Biochem Parasitol. 2014 Jun 21;195(1):23-29. PMID: 24955523.

Chan JD, Zarowiecki M, Marchant JS. Ca2+ channels and praziquantel: a view from the free world. Parasitol Int. 2013 Dec;62(6):619-28. PMID: 23246536.

Crosby A, Jones FM, Kolosionek E, et al. Praziquantel reverses pulmonary hypertension and vascular remodeling in murine schistosomiasis. Am J Respir Crit Care Med. 2011 Aug 15;184(4):467-73. PMID: 21659614.

" None Not dangerous goods.

LKT P0351 Pancreatic Polypeptide, rat 0.5 mg 300.1 Endogenous peptide, regulates pancreatic cell signaling; Y4 agonist. 90419-12-8 ≥98% 4398.9 C195H298N58O57S Ambient -20°C "Kahleova H, Mari A, Nofrate V, et al. Improvement in β-cell function after diet-induced weight loss is associated with decrease in pancreatic polypeptide in subjects with type 2 diabetes. J Diabetes Complications. 2012 Sep-Oct;26(5):442-9. PMID: 22673566.

Hankir MK, Parkinson JR, Minnion JS, et al. Peptide YY 3-36 and pancreatic polypeptide differentially regulate hypothalamic neuronal activity in mice in vivo as measured by manganese-enhanced magnetic resonance imaging. J Neuroendocrinol. 2011 Apr;23(4):371-80. PMID: 21251093.

Moriya R, Fujikawa T, Ito J, et al. Pancreatic polypeptide enhances colonic muscle contraction and fecal output through neuropeptide Y Y4 receptor in mice. Eur J Pharmacol. 2010 Feb 10;627(1-3):258-64. PMID: 19818748.

Liu YL, Semjonous NM, Murphy KG, et al. The effects of pancreatic polypeptide on locomotor activity and food intake in mice. Int J Obes (Lond). 2008 Nov;32(11):1712-5. PMID: 18779824.

" Not dangerous goods.

LKT P0351 Pancreatic Polypeptide, rat 1 mg 510 Endogenous peptide, regulates pancreatic cell signaling; Y4 agonist. 90419-12-8 ≥98% 4398.9 C195H298N58O57S Ambient -20°C "Kahleova H, Mari A, Nofrate V, et al. Improvement in β-cell function after diet-induced weight loss is associated with decrease in pancreatic polypeptide in subjects with type 2 diabetes. J Diabetes Complications. 2012 Sep-Oct;26(5):442-9. PMID: 22673566.

Hankir MK, Parkinson JR, Minnion JS, et al. Peptide YY 3-36 and pancreatic polypeptide differentially regulate hypothalamic neuronal activity in mice in vivo as measured by manganese-enhanced magnetic resonance imaging. J Neuroendocrinol. 2011 Apr;23(4):371-80. PMID: 21251093.

Moriya R, Fujikawa T, Ito J, et al. Pancreatic polypeptide enhances colonic muscle contraction and fecal output through neuropeptide Y Y4 receptor in mice. Eur J Pharmacol. 2010 Feb 10;627(1-3):258-64. PMID: 19818748.

Liu YL, Semjonous NM, Murphy KG, et al. The effects of pancreatic polypeptide on locomotor activity and food intake in mice. Int J Obes (Lond). 2008 Nov;32(11):1712-5. PMID: 18779824.

" Not dangerous goods.

LKT P0351 Pancreatic Polypeptide, rat 2.5 mg 900.1 Endogenous peptide, regulates pancreatic cell signaling; Y4 agonist. 90419-12-8 ≥98% 4398.9 C195H298N58O57S Ambient -20°C "Kahleova H, Mari A, Nofrate V, et al. Improvement in β-cell function after diet-induced weight loss is associated with decrease in pancreatic polypeptide in subjects with type 2 diabetes. J Diabetes Complications. 2012 Sep-Oct;26(5):442-9. PMID: 22673566.

Hankir MK, Parkinson JR, Minnion JS, et al. Peptide YY 3-36 and pancreatic polypeptide differentially regulate hypothalamic neuronal activity in mice in vivo as measured by manganese-enhanced magnetic resonance imaging. J Neuroendocrinol. 2011 Apr;23(4):371-80. PMID: 21251093.

Moriya R, Fujikawa T, Ito J, et al. Pancreatic polypeptide enhances colonic muscle contraction and fecal output through neuropeptide Y Y4 receptor in mice. Eur J Pharmacol. 2010 Feb 10;627(1-3):258-64. PMID: 19818748.

Liu YL, Semjonous NM, Murphy KG, et al. The effects of pancreatic polypeptide on locomotor activity and food intake in mice. Int J Obes (Lond). 2008 Nov;32(11):1712-5. PMID: 18779824.

" Not dangerous goods.

LKT P0352 Pancreastatin, pig 0.5 mg 720.2 Endogenous peptide, involved in insulin signaling; GRP78 inhibitor. PST ≥98% 5103.4 C214H330N68O76S Ambient -20°C "Biswas N, Friese RS, Gayen JR, et al. Discovery of a novel target for the dysglycemic chromogranin A fragment pancreastatin: interaction with the chaperone GRP78 to influence metabolism. PLoS One. 2014 Jan 20;9(1):e84132. PMID: 24465394.

Rustagi S, Warner RR, Divino CM. Serum pancreastatin: the next predictive neuroendocrine tumor marker. J Surg Oncol. 2013 Aug;108(2):126-8. PMID: 23775817.

Sánchez-Margalet V, González-Yanes C, Najib S, et al. Metabolic effects and mechanism of action of the chromogranin A-derived peptide pancreastatin. Regul Pept. 2010 Apr 9;161(1-3):8-14. PMID: 20184923.

"

LKT P0352 Pancreastatin, pig 1 mg 1224.1 Endogenous peptide, involved in insulin signaling; GRP78 inhibitor. PST ≥98% 5103.4 C214H330N68O76S Ambient -20°C "Biswas N, Friese RS, Gayen JR, et al. Discovery of a novel target for the dysglycemic chromogranin A fragment pancreastatin: interaction with the chaperone GRP78 to influence metabolism. PLoS One. 2014 Jan 20;9(1):e84132. PMID: 24465394.

Rustagi S, Warner RR, Divino CM. Serum pancreastatin: the next predictive neuroendocrine tumor marker. J Surg Oncol. 2013 Aug;108(2):126-8. PMID: 23775817.

Sánchez-Margalet V, González-Yanes C, Najib S, et al. Metabolic effects and mechanism of action of the chromogranin A-derived peptide pancreastatin. Regul Pept. 2010 Apr 9;161(1-3):8-14. PMID: 20184923.

"

LKT P0352 Pancreastatin, pig 2.5 mg 2160.1 Endogenous peptide, involved in insulin signaling; GRP78 inhibitor. PST ≥98% 5103.4 C214H330N68O76S Ambient -20°C "Biswas N, Friese RS, Gayen JR, et al. Discovery of a novel target for the dysglycemic chromogranin A fragment pancreastatin: interaction with the chaperone GRP78 to influence metabolism. PLoS One. 2014 Jan 20;9(1):e84132. PMID: 24465394.

Rustagi S, Warner RR, Divino CM. Serum pancreastatin: the next predictive neuroendocrine tumor marker. J Surg Oncol. 2013 Aug;108(2):126-8. PMID: 23775817.

Sánchez-Margalet V, González-Yanes C, Najib S, et al. Metabolic effects and mechanism of action of the chromogranin A-derived peptide pancreastatin. Regul Pept. 2010 Apr 9;161(1-3):8-14. PMID: 20184923.

"

LKT P0353 Pancreatic Polypeptide, human 0.5 mg 204.1 Endogenous peptide, regulates pancreatic cell signaling; Y4 agonist. 75976-10-2 ≥98% 4181.7 C185H287N53O54S2 Ambient -20°C "Kahleova H, Mari A, Nofrate V, et al. Improvement in β-cell function after diet-induced weight loss is associated with decrease in pancreatic polypeptide in subjects with type 2 diabetes. J Diabetes Complications. 2012 Sep-Oct;26(5):442-9. PMID: 22673566.

Hankir MK, Parkinson JR, Minnion JS, et al. Peptide YY 3-36 and pancreatic polypeptide differentially regulate hypothalamic neuronal activity in mice in vivo as measured by manganese-enhanced magnetic resonance imaging. J Neuroendocrinol. 2011 Apr;23(4):371-80. PMID: 21251093.

Moriya R, Fujikawa T, Ito J, et al. Pancreatic polypeptide enhances colonic muscle contraction and fecal output through neuropeptide Y Y4 receptor in mice. Eur J Pharmacol. 2010 Feb 10;627(1-3):258-64. PMID: 19818748.

Liu YL, Semjonous NM, Murphy KG, et al. The effects of pancreatic polypeptide on locomotor activity and food intake in mice. Int J Obes (Lond). 2008 Nov;32(11):1712-5. PMID: 18779824.

" Not dangerous goods.

LKT P0353 Pancreatic Polypeptide, human 1 mg 348 Endogenous peptide, regulates pancreatic cell signaling; Y4 agonist. 75976-10-2 ≥98% 4181.7 C185H287N53O54S2 Ambient -20°C "Kahleova H, Mari A, Nofrate V, et al. Improvement in β-cell function after diet-induced weight loss is associated with decrease in pancreatic polypeptide in subjects with type 2 diabetes. J Diabetes Complications. 2012 Sep-Oct;26(5):442-9. PMID: 22673566.

Hankir MK, Parkinson JR, Minnion JS, et al. Peptide YY 3-36 and pancreatic polypeptide differentially regulate hypothalamic neuronal activity in mice in vivo as measured by manganese-enhanced magnetic resonance imaging. J Neuroendocrinol. 2011 Apr;23(4):371-80. PMID: 21251093.

Moriya R, Fujikawa T, Ito J, et al. Pancreatic polypeptide enhances colonic muscle contraction and fecal output through neuropeptide Y Y4 receptor in mice. Eur J Pharmacol. 2010 Feb 10;627(1-3):258-64. PMID: 19818748.

Liu YL, Semjonous NM, Murphy KG, et al. The effects of pancreatic polypeptide on locomotor activity and food intake in mice. Int J Obes (Lond). 2008 Nov;32(11):1712-5. PMID: 18779824.

" Not dangerous goods.

LKT P0353 Pancreatic Polypeptide, human 2.5 mg 612.4 Endogenous peptide, regulates pancreatic cell signaling; Y4 agonist. 75976-10-2 ≥98% 4181.7 C185H287N53O54S2 Ambient -20°C "Kahleova H, Mari A, Nofrate V, et al. Improvement in β-cell function after diet-induced weight loss is associated with decrease in pancreatic polypeptide in subjects with type 2 diabetes. J Diabetes Complications. 2012 Sep-Oct;26(5):442-9. PMID: 22673566.

Hankir MK, Parkinson JR, Minnion JS, et al. Peptide YY 3-36 and pancreatic polypeptide differentially regulate hypothalamic neuronal activity in mice in vivo as measured by manganese-enhanced magnetic resonance imaging. J Neuroendocrinol. 2011 Apr;23(4):371-80. PMID: 21251093.

Moriya R, Fujikawa T, Ito J, et al. Pancreatic polypeptide enhances colonic muscle contraction and fecal output through neuropeptide Y Y4 receptor in mice. Eur J Pharmacol. 2010 Feb 10;627(1-3):258-64. PMID: 19818748.

Liu YL, Semjonous NM, Murphy KG, et al. The effects of pancreatic polypeptide on locomotor activity and food intake in mice. Int J Obes (Lond). 2008 Nov;32(11):1712-5. PMID: 18779824.

" Not dangerous goods.

LKT P0370 Paromomycin Sulfate 1 g 40.7 Aminoglycoside; protein translation inhibitor, cation (PX2X) channel blocker. "D-Streptamine, O-2-amino-2-deoxy-alpha-D-glucopyranosyl-(1-

>4)-O-(O-2,6-diamino-2,6-dideoxy-beta-L-idopyranosyl-(1->3)-

beta-D-ribofuranosyl-(1->5))-2-deoxy-, sulfate (salt) 

" Aminosidin sulfate; Gabbroral; Aminoxidin; Farmiglucin; Humagel; Humatin; Pargonyl; Sinosid. 1263-89-4 ≥98% 713.71 C23H45N5O14S H2SO4 C1C(C(C(C(C1N)OC2C(C(C(C(O2)CO)O)O)N)OC3C(C(C(O3)CO)OC4C(C(C(C(O4)CN)O)O)N)O)O)N.OS(=O)(=O)O Ambient Ambient +50° ~ +55° Soluble in water (>100 mg/mL). "Bongartz EV, Rettinger J, Hausmann R. Aminoglycoside block of P2X2 receptors heterologously expressed in Xenopus laevis oocytes. Purinergic Signal. 2010 Dec;6(4):393-403. PMID: 21437010.

Jhingran A, Chawla B, Saxena S, et al. Paromomycin: uptake and resistance in Leishmania donovani. Mol Biochem Parasitol. 2009 Apr;164(2):111-7. PMID: 19146886.

Borovinskaya MA, Pai RD, Zhang W, et al. Structural basis for aminoglycoside inhibition of bacterial ribosome recycling. Nat Struct Mol Biol. 2007 Aug;14(8):727-32. PMID: 17660832.

" None Not dangerous goods.

LKT P0370 Paromomycin Sulfate 5 g 163.2 Aminoglycoside; protein translation inhibitor, cation (PX2X) channel blocker. "D-Streptamine, O-2-amino-2-deoxy-alpha-D-glucopyranosyl-(1-

>4)-O-(O-2,6-diamino-2,6-dideoxy-beta-L-idopyranosyl-(1->3)-

beta-D-ribofuranosyl-(1->5))-2-deoxy-, sulfate (salt) 

" Aminosidin sulfate; Gabbroral; Aminoxidin; Farmiglucin; Humagel; Humatin; Pargonyl; Sinosid. 1263-89-4 ≥98% 713.71 C23H45N5O14S H2SO4 C1C(C(C(C(C1N)OC2C(C(C(C(O2)CO)O)O)N)OC3C(C(C(O3)CO)OC4C(C(C(C(O4)CN)O)O)N)O)O)N.OS(=O)(=O)O Ambient Ambient +50° ~ +55° Soluble in water (>100 mg/mL). "Bongartz EV, Rettinger J, Hausmann R. Aminoglycoside block of P2X2 receptors heterologously expressed in Xenopus laevis oocytes. Purinergic Signal. 2010 Dec;6(4):393-403. PMID: 21437010.

Jhingran A, Chawla B, Saxena S, et al. Paromomycin: uptake and resistance in Leishmania donovani. Mol Biochem Parasitol. 2009 Apr;164(2):111-7. PMID: 19146886.

Borovinskaya MA, Pai RD, Zhang W, et al. Structural basis for aminoglycoside inhibition of bacterial ribosome recycling. Nat Struct Mol Biol. 2007 Aug;14(8):727-32. PMID: 17660832.

" None Not dangerous goods.

LKT P0370 Paromomycin Sulfate 25 g 611.5 Aminoglycoside; protein translation inhibitor, cation (PX2X) channel blocker. "D-Streptamine, O-2-amino-2-deoxy-alpha-D-glucopyranosyl-(1-

>4)-O-(O-2,6-diamino-2,6-dideoxy-beta-L-idopyranosyl-(1->3)-

beta-D-ribofuranosyl-(1->5))-2-deoxy-, sulfate (salt) 

" Aminosidin sulfate; Gabbroral; Aminoxidin; Farmiglucin; Humagel; Humatin; Pargonyl; Sinosid. 1263-89-4 ≥98% 713.71 C23H45N5O14S H2SO4 C1C(C(C(C(C1N)OC2C(C(C(C(O2)CO)O)O)N)OC3C(C(C(O3)CO)OC4C(C(C(C(O4)CN)O)O)N)O)O)N.OS(=O)(=O)O Ambient Ambient +50° ~ +55° Soluble in water (>100 mg/mL). "Bongartz EV, Rettinger J, Hausmann R. Aminoglycoside block of P2X2 receptors heterologously expressed in Xenopus laevis oocytes. Purinergic Signal. 2010 Dec;6(4):393-403. PMID: 21437010.

Jhingran A, Chawla B, Saxena S, et al. Paromomycin: uptake and resistance in Leishmania donovani. Mol Biochem Parasitol. 2009 Apr;164(2):111-7. PMID: 19146886.

Borovinskaya MA, Pai RD, Zhang W, et al. Structural basis for aminoglycoside inhibition of bacterial ribosome recycling. Nat Struct Mol Biol. 2007 Aug;14(8):727-32. PMID: 17660832.

" None Not dangerous goods.

LKT P7082 Prulifloxacin 25 mg 33.9 Fluoroquinolone; topoisomerase IV and bacterial DNA gyrase inhibitor. "1H,4H-(1,3)Thiazeto(3,2-a)quinoline-3-carboxylic acid, 6-fluoro-1-methyl-7-(4-((5-methyl-2-oxo-1,3-dioxol-4-

yl)methyl)-1-piperazinyl)-4-oxo- " (+-)-7-(4-((Z)-2,3-Dihydroxy-2-butenyl)-1-piperazinyl)-6-fluoro-1-methyl-4-oxo-1H,4H-(1,3)thiazeto(3,2-a)quinoline-3-carboxylic acid, cyclic carbonate 123447-62-1 ≥97% 461.46 C21H20FN3O6S CC1N2C3=CC(=C(C=C3C(=O)C(=C2S1)C(=O)O)F)N4CCN(CC4)CC5=C(OC(=O)O5)C Ambient Ambient "soluble in 0.1 mol/L NaOH,slightly soluble in acetonitrile and glacial

acetic acid£¨practically insoluble in water,methanol ethanol and 0.1mol

£ØL HCL£ª

" "Karageorgopoulos DE, Maraki S, Vatopoulos AC, et al. Antimicrobial activity of prulifloxacin in comparison with other fluoroquinolones against community-acquired urinary and respiratory pathogens isolated in Greece. Eur J Clin Microbiol Infect Dis. 2013 Nov;32(11):1417-22. PMID: 23686506.

Castora FJ, Vissering FF, Simpson MV. The effect of bacterial DNA gyrase inhibitors on DNA synthesis in mammalian mitochondria. Biochim Biophys Acta. 1983 Sep 9;740(4):417-27. PMID: 6309236.

" None Not dangerous goods.

LKT P7082 Prulifloxacin 100 mg 54.4 Fluoroquinolone; topoisomerase IV and bacterial DNA gyrase inhibitor. "1H,4H-(1,3)Thiazeto(3,2-a)quinoline-3-carboxylic acid, 6-fluoro-1-methyl-7-(4-((5-methyl-2-oxo-1,3-dioxol-4-

yl)methyl)-1-piperazinyl)-4-oxo- " (+-)-7-(4-((Z)-2,3-Dihydroxy-2-butenyl)-1-piperazinyl)-6-fluoro-1-methyl-4-oxo-1H,4H-(1,3)thiazeto(3,2-a)quinoline-3-carboxylic acid, cyclic carbonate 123447-62-1 ≥97% 461.46 C21H20FN3O6S CC1N2C3=CC(=C(C=C3C(=O)C(=C2S1)C(=O)O)F)N4CCN(CC4)CC5=C(OC(=O)O5)C Ambient Ambient "soluble in 0.1 mol/L NaOH,slightly soluble in acetonitrile and glacial

acetic acid£¨practically insoluble in water,methanol ethanol and 0.1mol

£ØL HCL£ª

" "Karageorgopoulos DE, Maraki S, Vatopoulos AC, et al. Antimicrobial activity of prulifloxacin in comparison with other fluoroquinolones against community-acquired urinary and respiratory pathogens isolated in Greece. Eur J Clin Microbiol Infect Dis. 2013 Nov;32(11):1417-22. PMID: 23686506.

Castora FJ, Vissering FF, Simpson MV. The effect of bacterial DNA gyrase inhibitors on DNA synthesis in mammalian mitochondria. Biochim Biophys Acta. 1983 Sep 9;740(4):417-27. PMID: 6309236.

" None Not dangerous goods.

LKT P7082 Prulifloxacin 500 mg 237.8 Fluoroquinolone; topoisomerase IV and bacterial DNA gyrase inhibitor. "1H,4H-(1,3)Thiazeto(3,2-a)quinoline-3-carboxylic acid, 6-fluoro-1-methyl-7-(4-((5-methyl-2-oxo-1,3-dioxol-4-

yl)methyl)-1-piperazinyl)-4-oxo- " (+-)-7-(4-((Z)-2,3-Dihydroxy-2-butenyl)-1-piperazinyl)-6-fluoro-1-methyl-4-oxo-1H,4H-(1,3)thiazeto(3,2-a)quinoline-3-carboxylic acid, cyclic carbonate 123447-62-1 ≥97% 461.46 C21H20FN3O6S CC1N2C3=CC(=C(C=C3C(=O)C(=C2S1)C(=O)O)F)N4CCN(CC4)CC5=C(OC(=O)O5)C Ambient Ambient "soluble in 0.1 mol/L NaOH,slightly soluble in acetonitrile and glacial

acetic acid£¨practically insoluble in water,methanol ethanol and 0.1mol

£ØL HCL£ª

" "Karageorgopoulos DE, Maraki S, Vatopoulos AC, et al. Antimicrobial activity of prulifloxacin in comparison with other fluoroquinolones against community-acquired urinary and respiratory pathogens isolated in Greece. Eur J Clin Microbiol Infect Dis. 2013 Nov;32(11):1417-22. PMID: 23686506.

Castora FJ, Vissering FF, Simpson MV. The effect of bacterial DNA gyrase inhibitors on DNA synthesis in mammalian mitochondria. Biochim Biophys Acta. 1983 Sep 9;740(4):417-27. PMID: 6309236.

" None Not dangerous goods.

LKT P0392 Paxilline 5 mg 221.3 Neuroactive mycotoxin produced by Penicillum and Aspergillus; BK K+ channel inhibitor, SERCA inhibitor. 57186-25-1 ≥98% 435.56 C27H33NO4 CC12CCC3C(=CC(=O)C(O3)C(C)(C)O)C1(CCC4C2(C5=C(C4)C6=CC=CC=C6N5)C)O Ambient 4°C Acetone, Methanol, and DMSO. "Borchert GH, Hlaváčková M, Kolář F. Pharmacological activation of mitochondrial BK(Ca) channels protects isolated cardiomyocytes against simulated reperfusion-induced injury. Exp Biol Med (Maywood). 2013 Feb;238(2):233-41. PMID: 23576804.

Bilmen JG, Wootton LL, Michelangeli F. The mechanism of inhibition of the sarco/endoplasmic reticulum Ca2+ ATPase by paxilline. Arch Biochem Biophys. 2002 Oct 1;406(1):55-64. PMID: 12234490." T, Xi "UN number: 2811     Class: 6.1     Packing Group: III

Proper shipping name: Toxic solid, organic, n.o.s. (Paxilline)"

LKT P0392 Paxilline 10 mg 405 Neuroactive mycotoxin produced by Penicillum and Aspergillus; BK K+ channel inhibitor, SERCA inhibitor. 57186-25-1 ≥98% 435.56 C27H33NO4 CC12CCC3C(=CC(=O)C(O3)C(C)(C)O)C1(CCC4C2(C5=C(C4)C6=CC=CC=C6N5)C)O Ambient 4°C Acetone, Methanol, and DMSO. "Borchert GH, Hlaváčková M, Kolář F. Pharmacological activation of mitochondrial BK(Ca) channels protects isolated cardiomyocytes against simulated reperfusion-induced injury. Exp Biol Med (Maywood). 2013 Feb;238(2):233-41. PMID: 23576804.

Bilmen JG, Wootton LL, Michelangeli F. The mechanism of inhibition of the sarco/endoplasmic reticulum Ca2+ ATPase by paxilline. Arch Biochem Biophys. 2002 Oct 1;406(1):55-64. PMID: 12234490." T, Xi "UN number: 2811     Class: 6.1     Packing Group: III

Proper shipping name: Toxic solid, organic, n.o.s. (Paxilline)"

LKT P0397 Pazopanib 5 mg 200.8 VEGFR, PDGFR, c-Kit inhibitor. 5-[[4-[(2,3-Dimethyl-2H-indazol-6-yl)methylamino]-2-pyrimidinyl]amino]-2-methyl-benzenesulfonamide 444731-52-6 ≥97% 437.53 C21H23N7O2S CC1=C(C=C(C=C1)NC2=NC=CC(=N2)N(C)C3=CC4=NN(C(=C4C=C3)C)C)S(=O)(=O)N Ambient Ambient "Pick AM, Nystrom KK. Pazopanib for the treatment of metastatic renal cell carcinoma. Clin Ther. 2012 Mar;34(3):511-20. PMID: 22341567.

Gril B, Palmieri D, Qian Y, et al. Pazopanib reveals a role for tumor cell B-Raf in the prevention of HER2+ breast cancer brain metastasis. Clin Cancer Res. 2011 Jan 1;17(1):142-53. PMID: 21081656.

Hamberg P, Verweij J, Sleijfer S. (Pre-)clinical pharmacology and activity of pazopanib, a novel multikinase angiogenesis inhibitor. Oncologist. 2010;15(6):539-47. PMID: 20511320.

" Not dangerous goods.

LKT P0397 Pazopanib 25 mg 837.2 VEGFR, PDGFR, c-Kit inhibitor. 5-[[4-[(2,3-Dimethyl-2H-indazol-6-yl)methylamino]-2-pyrimidinyl]amino]-2-methyl-benzenesulfonamide 444731-52-6 ≥97% 437.53 C21H23N7O2S CC1=C(C=C(C=C1)NC2=NC=CC(=N2)N(C)C3=CC4=NN(C(=C4C=C3)C)C)S(=O)(=O)N Ambient Ambient "Pick AM, Nystrom KK. Pazopanib for the treatment of metastatic renal cell carcinoma. Clin Ther. 2012 Mar;34(3):511-20. PMID: 22341567.

Gril B, Palmieri D, Qian Y, et al. Pazopanib reveals a role for tumor cell B-Raf in the prevention of HER2+ breast cancer brain metastasis. Clin Cancer Res. 2011 Jan 1;17(1):142-53. PMID: 21081656.

Hamberg P, Verweij J, Sleijfer S. (Pre-)clinical pharmacology and activity of pazopanib, a novel multikinase angiogenesis inhibitor. Oncologist. 2010;15(6):539-47. PMID: 20511320.

" Not dangerous goods.

LKT P0398 Pazufloxacin Methanesulfonate 500 mg 208 Fluoroquinolone; topoisomerase IV and bacterial DNA gyrase inhibitor. (3S)-10-(1-Aminocyclopropyl)-9-fluoro-2,3-dihydro-3-methyl-7-oxo-7H-pyrido[1,2,3-de]-1,4-benzoxazine-6- carboxylic acid Pazufloxacin mesylate 163680-77-1 ≥98% 414.41 C16H15FN2O4 CH3SO3H CC1COC2=C3N1C=C(C(=O)C3=CC(=C2C4(CC4)N)F)C(=O)O.CS(=O)(=O)O Ambient Ambient Soluble in water. "Higa F, Akamine M, Haranaga S, et al. In vitro activity of pazufloxacin, tosufloxacin and other quinolones against Legionella species. J Antimicrob Chemother. 2005 Dec;56(6):1053-7. PMID: 16260445.

Takei M, Fukuda H, Kishii R, et al. Target preference of 15 quinolones against Staphylococcus aureus, based on antibacterial activities and target inhibition. Antimicrob Agents Chemother. 2001 Dec;45(12):3544-7. PMID: 11709337.

Mikamo H, Sato Y, Hayasaki Y, et al. In vitro activities of pazufloxacin, a novel injectable quinolone, against bacteria causing infections in obstetric and gynecological patients. Chemotherapy. 1999 May-Jun;45(3):154-7. PMID: 10224336.

" Xi, C, F Not dangerous goods.

LKT P0398 Pazufloxacin Methanesulfonate 1 g 300.3 Fluoroquinolone; topoisomerase IV and bacterial DNA gyrase inhibitor. (3S)-10-(1-Aminocyclopropyl)-9-fluoro-2,3-dihydro-3-methyl-7-oxo-7H-pyrido[1,2,3-de]-1,4-benzoxazine-6- carboxylic acid Pazufloxacin mesylate 163680-77-1 ≥98% 414.41 C16H15FN2O4 CH3SO3H CC1COC2=C3N1C=C(C(=O)C3=CC(=C2C4(CC4)N)F)C(=O)O.CS(=O)(=O)O Ambient Ambient Soluble in water. "Higa F, Akamine M, Haranaga S, et al. In vitro activity of pazufloxacin, tosufloxacin and other quinolones against Legionella species. J Antimicrob Chemother. 2005 Dec;56(6):1053-7. PMID: 16260445.

Takei M, Fukuda H, Kishii R, et al. Target preference of 15 quinolones against Staphylococcus aureus, based on antibacterial activities and target inhibition. Antimicrob Agents Chemother. 2001 Dec;45(12):3544-7. PMID: 11709337.

Mikamo H, Sato Y, Hayasaki Y, et al. In vitro activities of pazufloxacin, a novel injectable quinolone, against bacteria causing infections in obstetric and gynecological patients. Chemotherapy. 1999 May-Jun;45(3):154-7. PMID: 10224336.

" Xi, C, F Not dangerous goods.

LKT P0398 Pazufloxacin Methanesulfonate 5 g 883.3 Fluoroquinolone; topoisomerase IV and bacterial DNA gyrase inhibitor. (3S)-10-(1-Aminocyclopropyl)-9-fluoro-2,3-dihydro-3-methyl-7-oxo-7H-pyrido[1,2,3-de]-1,4-benzoxazine-6- carboxylic acid Pazufloxacin mesylate 163680-77-1 ≥98% 414.41 C16H15FN2O4 CH3SO3H CC1COC2=C3N1C=C(C(=O)C3=CC(=C2C4(CC4)N)F)C(=O)O.CS(=O)(=O)O Ambient Ambient Soluble in water. "Higa F, Akamine M, Haranaga S, et al. In vitro activity of pazufloxacin, tosufloxacin and other quinolones against Legionella species. J Antimicrob Chemother. 2005 Dec;56(6):1053-7. PMID: 16260445.

Takei M, Fukuda H, Kishii R, et al. Target preference of 15 quinolones against Staphylococcus aureus, based on antibacterial activities and target inhibition. Antimicrob Agents Chemother. 2001 Dec;45(12):3544-7. PMID: 11709337.

Mikamo H, Sato Y, Hayasaki Y, et al. In vitro activities of pazufloxacin, a novel injectable quinolone, against bacteria causing infections in obstetric and gynecological patients. Chemotherapy. 1999 May-Jun;45(3):154-7. PMID: 10224336.

" Xi, C, F Not dangerous goods.

LKT P1622 Pefloxacin Methanesulfonate Dihydrate 5 g 40.7 Fluoroquinolone; topoisomerase IV and bacterial DNA gyrase inhibitor. 1-ethyl-6-fluoro-1,4-dihydro-7-(4-methyl-1- piperazinyl)-4-oxo-3-quinolinecarboxylic acid monomethanesulfonate Pefloxacine mesylate; Peflacine; Peflox 149676-40-4 ≥98% 465.5 C17H20FN3O3 CH3SO3H 2H2O CCN1C=C(C(=O)C2=CC(=C(C=C21)N3CCN(CC3)C)F)C(=O)O Ambient Ambient "Martínez LJ, Sik RH, Chignell CF. Fluoroquinolone antimicrobials: singlet oxygen, superoxide and phototoxicity. Photochem Photobiol. 1998 Apr;67(4):399-403. PMID: 9559584.

Grossato A, Fontana R. Synergy and mechanism of interaction between pefloxacin and penicillin G against enterococci. New Microbiol. 1997 Jul;20(3):221-5. PMID: 9258941.

Moreau NJ, Houot S, Joly-Guillou ML, et al. Characterisation of DNA gyrase and measurement of drug accumulation in clinical isolates of Acinetobacter baumannii resistant to fluoroquinolones. J Antimicrob Chemother. 1996 Dec;38(6):1079-83. PMID: 9023657.

" Xn Not dangerous goods.

LKT P1622 Pefloxacin Methanesulfonate Dihydrate 25 g 163.2 Fluoroquinolone; topoisomerase IV and bacterial DNA gyrase inhibitor. 1-ethyl-6-fluoro-1,4-dihydro-7-(4-methyl-1- piperazinyl)-4-oxo-3-quinolinecarboxylic acid monomethanesulfonate Pefloxacine mesylate; Peflacine; Peflox 149676-40-4 ≥98% 465.5 C17H20FN3O3 CH3SO3H 2H2O CCN1C=C(C(=O)C2=CC(=C(C=C21)N3CCN(CC3)C)F)C(=O)O Ambient Ambient "Martínez LJ, Sik RH, Chignell CF. Fluoroquinolone antimicrobials: singlet oxygen, superoxide and phototoxicity. Photochem Photobiol. 1998 Apr;67(4):399-403. PMID: 9559584.

Grossato A, Fontana R. Synergy and mechanism of interaction between pefloxacin and penicillin G against enterococci. New Microbiol. 1997 Jul;20(3):221-5. PMID: 9258941.

Moreau NJ, Houot S, Joly-Guillou ML, et al. Characterisation of DNA gyrase and measurement of drug accumulation in clinical isolates of Acinetobacter baumannii resistant to fluoroquinolones. J Antimicrob Chemother. 1996 Dec;38(6):1079-83. PMID: 9023657.

" Xn Not dangerous goods.

LKT P1622 Pefloxacin Methanesulfonate Dihydrate 100 g 271.7 Fluoroquinolone; topoisomerase IV and bacterial DNA gyrase inhibitor. 1-ethyl-6-fluoro-1,4-dihydro-7-(4-methyl-1- piperazinyl)-4-oxo-3-quinolinecarboxylic acid monomethanesulfonate Pefloxacine mesylate; Peflacine; Peflox 149676-40-4 ≥98% 465.5 C17H20FN3O3 CH3SO3H 2H2O CCN1C=C(C(=O)C2=CC(=C(C=C21)N3CCN(CC3)C)F)C(=O)O Ambient Ambient "Martínez LJ, Sik RH, Chignell CF. Fluoroquinolone antimicrobials: singlet oxygen, superoxide and phototoxicity. Photochem Photobiol. 1998 Apr;67(4):399-403. PMID: 9559584.

Grossato A, Fontana R. Synergy and mechanism of interaction between pefloxacin and penicillin G against enterococci. New Microbiol. 1997 Jul;20(3):221-5. PMID: 9258941.

Moreau NJ, Houot S, Joly-Guillou ML, et al. Characterisation of DNA gyrase and measurement of drug accumulation in clinical isolates of Acinetobacter baumannii resistant to fluoroquinolones. J Antimicrob Chemother. 1996 Dec;38(6):1079-83. PMID: 9023657.

" Xn Not dangerous goods.

LKT P7059 Proxymetacaine Hydrochloride 100 mg 42.4 Potential voltage-gated Na+ channel blocker. 5875-06-9 ≥98% 330.85 C16H26N2O38 HCl CCCOC1=C(C=C(C=C1)C(=O)OCCN(CC)CC)N.Cl Ambient Ambient "Murphy PJ, Ntola AM. Prolonged corneal anaesthesia by proxymetacaine hydrochloride detected by a thermal cooling stimulus. Cont Lens Anterior Eye. 2009 Apr;32(2):84-7; quiz 99-100. PMID: 19181566.

Jauregui MJ, Sanders TJ, Polse KA. Anesthetic effects from low concentrations of proparacaine and benoxinate. J Am Optom Assoc. 1980 Jan;51(1):37-41. PMID: 6997360.

" Not dangerous goods.

LKT P7059 Proxymetacaine Hydrochloride 250 mg 78.9 Potential voltage-gated Na+ channel blocker. 5875-06-9 ≥98% 330.85 C16H26N2O38 HCl CCCOC1=C(C=C(C=C1)C(=O)OCCN(CC)CC)N.Cl Ambient Ambient "Murphy PJ, Ntola AM. Prolonged corneal anaesthesia by proxymetacaine hydrochloride detected by a thermal cooling stimulus. Cont Lens Anterior Eye. 2009 Apr;32(2):84-7; quiz 99-100. PMID: 19181566.

Jauregui MJ, Sanders TJ, Polse KA. Anesthetic effects from low concentrations of proparacaine and benoxinate. J Am Optom Assoc. 1980 Jan;51(1):37-41. PMID: 6997360.

" Not dangerous goods.

LKT P7059 Proxymetacaine Hydrochloride 1 g 145.6 Potential voltage-gated Na+ channel blocker. 5875-06-9 ≥98% 330.85 C16H26N2O38 HCl CCCOC1=C(C=C(C=C1)C(=O)OCCN(CC)CC)N.Cl Ambient Ambient "Murphy PJ, Ntola AM. Prolonged corneal anaesthesia by proxymetacaine hydrochloride detected by a thermal cooling stimulus. Cont Lens Anterior Eye. 2009 Apr;32(2):84-7; quiz 99-100. PMID: 19181566.

Jauregui MJ, Sanders TJ, Polse KA. Anesthetic effects from low concentrations of proparacaine and benoxinate. J Am Optom Assoc. 1980 Jan;51(1):37-41. PMID: 6997360.

" Not dangerous goods.

LKT P1753 Penicillamine 1 g 33.9 Penicillin derivative, chelating agent; carboxypeptidase inhibitor. 3-Mercapto-D-valine Cuprimine; Depen; DMC; D-Penamine; Mercaptyl; Pendramine; Sufortan; Trolovol 52-67-5 ≥97% 149.21 C5H11NO2S CC(C)(C(C(=O)O)N)S Ambient Ambient Soluble in water. Slightly soluble in alcohol. Insoluble in ether, acetone, benzene, and carbon tetrachloride. "Chong CR, Auld DS. Inhibition of carboxypeptidase A by D-penicillamine: mechanism and implications for drug design. Biochemistry. 2000 Jun 27;39(25):7580-8. PMID: 10858308.

Meyer O. D-penicillamine: mechanism of cellular action and induced autoimmune diseases. Rev Rhum Mal Osteoartic. 1986 Jan;53(1):15-20. PMID: 2939541.

Camp AV. Penicillamine in the treatment of rheumatoid arthritis. Proc R Soc Med. 1977 Feb;70(2):67-9. PMID: 859814.

" Xi Not dangerous goods.

LKT P1753 Penicillamine 5 g 108.8 Penicillin derivative, chelating agent; carboxypeptidase inhibitor. 3-Mercapto-D-valine Cuprimine; Depen; DMC; D-Penamine; Mercaptyl; Pendramine; Sufortan; Trolovol 52-67-5 ≥97% 149.21 C5H11NO2S CC(C)(C(C(=O)O)N)S Ambient Ambient Soluble in water. Slightly soluble in alcohol. Insoluble in ether, acetone, benzene, and carbon tetrachloride. "Chong CR, Auld DS. Inhibition of carboxypeptidase A by D-penicillamine: mechanism and implications for drug design. Biochemistry. 2000 Jun 27;39(25):7580-8. PMID: 10858308.

Meyer O. D-penicillamine: mechanism of cellular action and induced autoimmune diseases. Rev Rhum Mal Osteoartic. 1986 Jan;53(1):15-20. PMID: 2939541.

Camp AV. Penicillamine in the treatment of rheumatoid arthritis. Proc R Soc Med. 1977 Feb;70(2):67-9. PMID: 859814.

" Xi Not dangerous goods.

LKT P1753 Penicillamine 25 g 407.7 Penicillin derivative, chelating agent; carboxypeptidase inhibitor. 3-Mercapto-D-valine Cuprimine; Depen; DMC; D-Penamine; Mercaptyl; Pendramine; Sufortan; Trolovol 52-67-5 ≥97% 149.21 C5H11NO2S CC(C)(C(C(=O)O)N)S Ambient Ambient Soluble in water. Slightly soluble in alcohol. Insoluble in ether, acetone, benzene, and carbon tetrachloride. "Chong CR, Auld DS. Inhibition of carboxypeptidase A by D-penicillamine: mechanism and implications for drug design. Biochemistry. 2000 Jun 27;39(25):7580-8. PMID: 10858308.

Meyer O. D-penicillamine: mechanism of cellular action and induced autoimmune diseases. Rev Rhum Mal Osteoartic. 1986 Jan;53(1):15-20. PMID: 2939541.

Camp AV. Penicillamine in the treatment of rheumatoid arthritis. Proc R Soc Med. 1977 Feb;70(2):67-9. PMID: 859814.

" Xi Not dangerous goods.

LKT P7058 Protocatechuic Aldehyde 10 g 61.1 Polyphenol found in various plants and foods. 3,4-Dihydroxybenzaldehyde    139-85-5    ≥98% 138.12 C7H6O3 C1=CC(=C(C=C1C=O)O)O Ambient Ambient 6310 mg/L H2O "Wei G, Guan Y, Yin Y, et al. Anti-inflammatory effect of protocatechuic aldehyde on myocardial ischemia/reperfusion injury in vivo and in vitro. Inflammation. 2013 Jun;36(3):592-602. PMID: 23269534.

Xing YL, Zhou Z, Agula, et al. Protocatechuic aldehyde inhibits lipopolysaccharide-induced human umbilical vein endothelial cell apoptosis via regulation of caspase-3. Phytother Res. 2012 Sep;26(9):1334-41. PMID: 22298410.

Xu Y, Jiang WL, Zhang SP, et al. Protocatechuic aldehyde protects against experimental sepsis in vitro and in vivo. Basic Clin Pharmacol Toxicol. 2012 Apr;110(4):384-9. PMID: 22050905.

" Xi Not dangerous goods.

LKT P7058 Protocatechuic Aldehyde 25 g 115.5 Polyphenol found in various plants and foods. 3,4-Dihydroxybenzaldehyde    139-85-5    ≥98% 138.12 C7H6O3 C1=CC(=C(C=C1C=O)O)O Ambient Ambient 6310 mg/L H2O "Wei G, Guan Y, Yin Y, et al. Anti-inflammatory effect of protocatechuic aldehyde on myocardial ischemia/reperfusion injury in vivo and in vitro. Inflammation. 2013 Jun;36(3):592-602. PMID: 23269534.

Xing YL, Zhou Z, Agula, et al. Protocatechuic aldehyde inhibits lipopolysaccharide-induced human umbilical vein endothelial cell apoptosis via regulation of caspase-3. Phytother Res. 2012 Sep;26(9):1334-41. PMID: 22298410.

Xu Y, Jiang WL, Zhang SP, et al. Protocatechuic aldehyde protects against experimental sepsis in vitro and in vivo. Basic Clin Pharmacol Toxicol. 2012 Apr;110(4):384-9. PMID: 22050905.

" Xi Not dangerous goods.

LKT P7058 Protocatechuic Aldehyde 100 g 305.9 Polyphenol found in various plants and foods. 3,4-Dihydroxybenzaldehyde    139-85-5    ≥98% 138.12 C7H6O3 C1=CC(=C(C=C1C=O)O)O Ambient Ambient 6310 mg/L H2O "Wei G, Guan Y, Yin Y, et al. Anti-inflammatory effect of protocatechuic aldehyde on myocardial ischemia/reperfusion injury in vivo and in vitro. Inflammation. 2013 Jun;36(3):592-602. PMID: 23269534.

Xing YL, Zhou Z, Agula, et al. Protocatechuic aldehyde inhibits lipopolysaccharide-induced human umbilical vein endothelial cell apoptosis via regulation of caspase-3. Phytother Res. 2012 Sep;26(9):1334-41. PMID: 22298410.

Xu Y, Jiang WL, Zhang SP, et al. Protocatechuic aldehyde protects against experimental sepsis in vitro and in vivo. Basic Clin Pharmacol Toxicol. 2012 Apr;110(4):384-9. PMID: 22050905.

" Xi Not dangerous goods.

LKT P1754 Penciclovir 100 mg 88.3 Nucleoside (guanosine) analog; DNA chain terminator, viral DNA polymerase inhibitor. 2-Amino-1,9-dihydro-9-[4-hydroxy-3-(hydroxy- methylbutyl]-6H-purin-6-one Denavir; Vectavir 39809-25-1 ≥98% 253.26 C10H15N5O3 C1=NC2=C(N1CCC(CO)CO)NC(=NC2=O)N Ambient Ambient Soluble in water. "Deval J. Antimicrobial strategies: inhibition of viral polymerases by 3'-hydroxyl nucleosides. Drugs. 2009;69(2):151-66. PMID: 19228073.

Villarreal EC. Current and potential therapies for the treatment of herpes-virus infections. Prog Drug Res. 2003;60:263-307. PMID: 12790345.

Balzarini J, Bohman C, Walker RT, et al. Comparative cytostatic activity of different antiherpetic drugs against herpes simplex virus thymidine kinase gene-transfected tumor cells. Mol Pharmacol. 1994 Jun;45(6):1253-8. PMID: 8022417.

" Xi Not dangerous goods.

LKT P1754 Penciclovir 500 mg 271.7 Nucleoside (guanosine) analog; DNA chain terminator, viral DNA polymerase inhibitor. 2-Amino-1,9-dihydro-9-[4-hydroxy-3-(hydroxy- methylbutyl]-6H-purin-6-one Denavir; Vectavir 39809-25-1 ≥98% 253.26 C10H15N5O3 C1=NC2=C(N1CCC(CO)CO)NC(=NC2=O)N Ambient Ambient Soluble in water. "Deval J. Antimicrobial strategies: inhibition of viral polymerases by 3'-hydroxyl nucleosides. Drugs. 2009;69(2):151-66. PMID: 19228073.

Villarreal EC. Current and potential therapies for the treatment of herpes-virus infections. Prog Drug Res. 2003;60:263-307. PMID: 12790345.

Balzarini J, Bohman C, Walker RT, et al. Comparative cytostatic activity of different antiherpetic drugs against herpes simplex virus thymidine kinase gene-transfected tumor cells. Mol Pharmacol. 1994 Jun;45(6):1253-8. PMID: 8022417.

" Xi Not dangerous goods.

LKT P1754 Penciclovir 1 g 441.6 Nucleoside (guanosine) analog; DNA chain terminator, viral DNA polymerase inhibitor. 2-Amino-1,9-dihydro-9-[4-hydroxy-3-(hydroxy- methylbutyl]-6H-purin-6-one Denavir; Vectavir 39809-25-1 ≥98% 253.26 C10H15N5O3 C1=NC2=C(N1CCC(CO)CO)NC(=NC2=O)N Ambient Ambient Soluble in water. "Deval J. Antimicrobial strategies: inhibition of viral polymerases by 3'-hydroxyl nucleosides. Drugs. 2009;69(2):151-66. PMID: 19228073.

Villarreal EC. Current and potential therapies for the treatment of herpes-virus infections. Prog Drug Res. 2003;60:263-307. PMID: 12790345.

Balzarini J, Bohman C, Walker RT, et al. Comparative cytostatic activity of different antiherpetic drugs against herpes simplex virus thymidine kinase gene-transfected tumor cells. Mol Pharmacol. 1994 Jun;45(6):1253-8. PMID: 8022417.

" Xi Not dangerous goods.

LKT P7056 Procaterol Hydrochloride 10 mg 140.7 β2-adrenergic agonist. 62929-91-3 ≥98% 326.82 C16H22N2O3 HCl CCC(C(C1=C2C=CC(=O)NC2=C(C=C1)O)O)NC(C)C.Cl Ambient Ambient "Bao W, Chen Q, Lin Y, et al. Efficacy of procaterol combined with inhaled budesonide for treatment of cough-variant asthma. Respirology. 2013 Nov;18 Suppl 3:53-61. PMID: 24188204.

Yoshida N, Muraguchi M, Kamata M, et al. Procaterol potentiates the anti-inflammatory activity of budesonide on eosinophil adhesion to lung fibroblasts. Int Arch Allergy Immunol. 2009;150(4):352-8. PMID: 19571567.

Koyama S, Sato E, Masubuchi T, et al. Procaterol inhibits IL-1beta- and TNF-alpha-mediated epithelial cell eosinophil chemotactic activity. Eur Respir J. 1999 Oct;14(4):767-75. PMID: 10573218.

Ohuchi K, Hirasawa N, Takeda H, et al. Mechanism of antianaphylactic action of beta-agonists in allergic inflammation of air pouch type in rats. Int Arch Allergy Appl Immunol. 1987;82(1):26-32. PMID: 2879797.

" None Not dangerous goods.

LKT P7056 Procaterol Hydrochloride 25 mg 300.1 β2-adrenergic agonist. 62929-91-3 ≥98% 326.82 C16H22N2O3 HCl CCC(C(C1=C2C=CC(=O)NC2=C(C=C1)O)O)NC(C)C.Cl Ambient Ambient "Bao W, Chen Q, Lin Y, et al. Efficacy of procaterol combined with inhaled budesonide for treatment of cough-variant asthma. Respirology. 2013 Nov;18 Suppl 3:53-61. PMID: 24188204.

Yoshida N, Muraguchi M, Kamata M, et al. Procaterol potentiates the anti-inflammatory activity of budesonide on eosinophil adhesion to lung fibroblasts. Int Arch Allergy Immunol. 2009;150(4):352-8. PMID: 19571567.

Koyama S, Sato E, Masubuchi T, et al. Procaterol inhibits IL-1beta- and TNF-alpha-mediated epithelial cell eosinophil chemotactic activity. Eur Respir J. 1999 Oct;14(4):767-75. PMID: 10573218.

Ohuchi K, Hirasawa N, Takeda H, et al. Mechanism of antianaphylactic action of beta-agonists in allergic inflammation of air pouch type in rats. Int Arch Allergy Appl Immunol. 1987;82(1):26-32. PMID: 2879797.

" None Not dangerous goods.

LKT P7056 Procaterol Hydrochloride 100 mg 1031.4 β2-adrenergic agonist. 62929-91-3 ≥98% 326.82 C16H22N2O3 HCl CCC(C(C1=C2C=CC(=O)NC2=C(C=C1)O)O)NC(C)C.Cl Ambient Ambient "Bao W, Chen Q, Lin Y, et al. Efficacy of procaterol combined with inhaled budesonide for treatment of cough-variant asthma. Respirology. 2013 Nov;18 Suppl 3:53-61. PMID: 24188204.

Yoshida N, Muraguchi M, Kamata M, et al. Procaterol potentiates the anti-inflammatory activity of budesonide on eosinophil adhesion to lung fibroblasts. Int Arch Allergy Immunol. 2009;150(4):352-8. PMID: 19571567.

Koyama S, Sato E, Masubuchi T, et al. Procaterol inhibits IL-1beta- and TNF-alpha-mediated epithelial cell eosinophil chemotactic activity. Eur Respir J. 1999 Oct;14(4):767-75. PMID: 10573218.

Ohuchi K, Hirasawa N, Takeda H, et al. Mechanism of antianaphylactic action of beta-agonists in allergic inflammation of air pouch type in rats. Int Arch Allergy Appl Immunol. 1987;82(1):26-32. PMID: 2879797.

" None Not dangerous goods.

LKT P7034 Prion Peptide (106-126), human 1 mg 144 Synthetic peptide fragment, prion protein analog; p75 NTR agonist. 148439-49-0 ≥95% 1912.28 C80H128N26O34S2 CC(C)CC(C(=O)NCC(=O)O)NC(=O)CNC(=O)CNC(=O)C(C(C)C)NC(=O)C(C(C)C)NC(=O)C(C)NC(=O)CNC(=O)C(C)NC(=O)C(C)NC(=O)C(C)NC(=O)C(C)NC(=O)CNC(=O)C(C)NC(=O)C(CCSC)NC(=O)C(CC1=CNC=N1)NC(=O)C(CCCCN)NC(=O)C(CCSC)NC(=O)C(CC(=O)N)NC(=O)C(C(C)O)NC(=O)C(CCCCN)N Ambient -20°C "Song K, Na JY, Oh MH, et al. Synthetic prion Peptide 106-126 resulted in an increase matrix metalloproteinases and inflammatory cytokines from rat astrocytes and microglial cells. Toxicol Res. 2012 Mar;28(1):5-9. PMID: 24278583.

Pietri M, Caprini A, Mouillet-Richard S, et al. Overstimulation of PrPC signaling pathways by prion peptide 106-126 causes oxidative injury of bioaminergic neuronal cells. J Biol Chem. 2006 Sep 22;281(38):28470-9. PMID: 16864581.

Ciesielski-Treska J, Grant NJ, Ulrich G, et al. Fibrillar prion peptide (106-126) and scrapie prion protein hamper phagocytosis in microglia. Glia. 2004 Apr 15;46(2):101-15. PMID: 15042579.

Della-Bianca V, Rossi F, Armato U, et al. Neurotrophin p75 receptor is involved in neuronal damage by prion peptide-(106-126). J Biol Chem. 2001 Oct 19;276(42):38929-33. PMID: 11489911.

" Not dangerous goods.

LKT P7034 Prion Peptide (106-126), human 2 mg 252.1 Synthetic peptide fragment, prion protein analog; p75 NTR agonist. 148439-49-0 ≥95% 1912.28 C80H128N26O34S2 CC(C)CC(C(=O)NCC(=O)O)NC(=O)CNC(=O)CNC(=O)C(C(C)C)NC(=O)C(C(C)C)NC(=O)C(C)NC(=O)CNC(=O)C(C)NC(=O)C(C)NC(=O)C(C)NC(=O)C(C)NC(=O)CNC(=O)C(C)NC(=O)C(CCSC)NC(=O)C(CC1=CNC=N1)NC(=O)C(CCCCN)NC(=O)C(CCSC)NC(=O)C(CC(=O)N)NC(=O)C(C(C)O)NC(=O)C(CCCCN)N Ambient -20°C "Song K, Na JY, Oh MH, et al. Synthetic prion Peptide 106-126 resulted in an increase matrix metalloproteinases and inflammatory cytokines from rat astrocytes and microglial cells. Toxicol Res. 2012 Mar;28(1):5-9. PMID: 24278583.

Pietri M, Caprini A, Mouillet-Richard S, et al. Overstimulation of PrPC signaling pathways by prion peptide 106-126 causes oxidative injury of bioaminergic neuronal cells. J Biol Chem. 2006 Sep 22;281(38):28470-9. PMID: 16864581.

Ciesielski-Treska J, Grant NJ, Ulrich G, et al. Fibrillar prion peptide (106-126) and scrapie prion protein hamper phagocytosis in microglia. Glia. 2004 Apr 15;46(2):101-15. PMID: 15042579.

Della-Bianca V, Rossi F, Armato U, et al. Neurotrophin p75 receptor is involved in neuronal damage by prion peptide-(106-126). J Biol Chem. 2001 Oct 19;276(42):38929-33. PMID: 11489911.

" Not dangerous goods.

LKT P7034 Prion Peptide (106-126), human 5 mg 365.9 Synthetic peptide fragment, prion protein analog; p75 NTR agonist. 148439-49-0 ≥95% 1912.28 C80H128N26O34S2 CC(C)CC(C(=O)NCC(=O)O)NC(=O)CNC(=O)CNC(=O)C(C(C)C)NC(=O)C(C(C)C)NC(=O)C(C)NC(=O)CNC(=O)C(C)NC(=O)C(C)NC(=O)C(C)NC(=O)C(C)NC(=O)CNC(=O)C(C)NC(=O)C(CCSC)NC(=O)C(CC1=CNC=N1)NC(=O)C(CCCCN)NC(=O)C(CCSC)NC(=O)C(CC(=O)N)NC(=O)C(C(C)O)NC(=O)C(CCCCN)N Ambient -20°C "Song K, Na JY, Oh MH, et al. Synthetic prion Peptide 106-126 resulted in an increase matrix metalloproteinases and inflammatory cytokines from rat astrocytes and microglial cells. Toxicol Res. 2012 Mar;28(1):5-9. PMID: 24278583.

Pietri M, Caprini A, Mouillet-Richard S, et al. Overstimulation of PrPC signaling pathways by prion peptide 106-126 causes oxidative injury of bioaminergic neuronal cells. J Biol Chem. 2006 Sep 22;281(38):28470-9. PMID: 16864581.

Ciesielski-Treska J, Grant NJ, Ulrich G, et al. Fibrillar prion peptide (106-126) and scrapie prion protein hamper phagocytosis in microglia. Glia. 2004 Apr 15;46(2):101-15. PMID: 15042579.

Della-Bianca V, Rossi F, Armato U, et al. Neurotrophin p75 receptor is involved in neuronal damage by prion peptide-(106-126). J Biol Chem. 2001 Oct 19;276(42):38929-33. PMID: 11489911.

" Not dangerous goods.

LKT P1755 Pentoxifylline 10 g 47.6 Xanthine derivative; adenosine A2 antagonist, PDE inhibitor. 3,7-Dihydro-3,7-dimethyl-1-(5-oxohexyl)-1H-purine- 2,6-dione Azupentat; Durapental; Oxpentifylline; Rentylin; Torental; Trental; Vazofirin 6493-05-6 ≥98% 278.31 C13H18N4O3 CC(=O)CCCCN1C(=O)C2=C(N=CN2C)N(C1=O)C Ambient Ambient Soluble in water and benzene. "Fang CC, Huang JW, Shyu RS, et al. Fibrin-Induced epithelial-to-mesenchymal transition of peritoneal mesothelial cells as a mechanism of peritoneal fibrosis: effects of pentoxifylline. PLoS One. 2012;7(9):e44765. PMID: 23028611

Nowak Ł, Zurowski D, Dobrogowski J, et al. Pentoxifylline modifies central and peripheral vagal mechanism in acute and chronic pain models. Folia Med Cracov. 2012;52(1-2):83-95. PMID: 23697217

Deree J, Martins JO, Melbostad H, et al. Insights into the regulation of TNF-alpha production in human mononuclear cells: the effects of non-specific phosphodiesterase inhibition. Clinics (Sao Paulo). 2008 Jun;63(3):321-8. PMID: 18568240.

Marques LJ, Zheng L, Poulakis N, et al. Pentoxifylline inhibits TNF-alpha production from human alveolar macrophages. Am J Respir Crit Care Med. 1999 Feb;159(2):508-11. PMID: 9927365.

Ward A, Clissold SP. Pentoxifylline. A review of its pharmacodynamic and pharmacokinetic properties, and its therapeutic efficacy. Drugs. 1987 Jul;34(1):50-97. PMID: 3308412.

" Xn Not dangerous goods.

LKT P1755 Pentoxifylline 50 g 101.9 Xanthine derivative; adenosine A2 antagonist, PDE inhibitor. 3,7-Dihydro-3,7-dimethyl-1-(5-oxohexyl)-1H-purine- 2,6-dione Azupentat; Durapental; Oxpentifylline; Rentylin; Torental; Trental; Vazofirin 6493-05-6 ≥98% 278.31 C13H18N4O3 CC(=O)CCCCN1C(=O)C2=C(N=CN2C)N(C1=O)C Ambient Ambient Soluble in water and benzene. "Fang CC, Huang JW, Shyu RS, et al. Fibrin-Induced epithelial-to-mesenchymal transition of peritoneal mesothelial cells as a mechanism of peritoneal fibrosis: effects of pentoxifylline. PLoS One. 2012;7(9):e44765. PMID: 23028611

Nowak Ł, Zurowski D, Dobrogowski J, et al. Pentoxifylline modifies central and peripheral vagal mechanism in acute and chronic pain models. Folia Med Cracov. 2012;52(1-2):83-95. PMID: 23697217

Deree J, Martins JO, Melbostad H, et al. Insights into the regulation of TNF-alpha production in human mononuclear cells: the effects of non-specific phosphodiesterase inhibition. Clinics (Sao Paulo). 2008 Jun;63(3):321-8. PMID: 18568240.

Marques LJ, Zheng L, Poulakis N, et al. Pentoxifylline inhibits TNF-alpha production from human alveolar macrophages. Am J Respir Crit Care Med. 1999 Feb;159(2):508-11. PMID: 9927365.

Ward A, Clissold SP. Pentoxifylline. A review of its pharmacodynamic and pharmacokinetic properties, and its therapeutic efficacy. Drugs. 1987 Jul;34(1):50-97. PMID: 3308412.

" Xn Not dangerous goods.

LKT P1755 Pentoxifylline 100 g 136 Xanthine derivative; adenosine A2 antagonist, PDE inhibitor. 3,7-Dihydro-3,7-dimethyl-1-(5-oxohexyl)-1H-purine- 2,6-dione Azupentat; Durapental; Oxpentifylline; Rentylin; Torental; Trental; Vazofirin 6493-05-6 ≥98% 278.31 C13H18N4O3 CC(=O)CCCCN1C(=O)C2=C(N=CN2C)N(C1=O)C Ambient Ambient Soluble in water and benzene. "Fang CC, Huang JW, Shyu RS, et al. Fibrin-Induced epithelial-to-mesenchymal transition of peritoneal mesothelial cells as a mechanism of peritoneal fibrosis: effects of pentoxifylline. PLoS One. 2012;7(9):e44765. PMID: 23028611

Nowak Ł, Zurowski D, Dobrogowski J, et al. Pentoxifylline modifies central and peripheral vagal mechanism in acute and chronic pain models. Folia Med Cracov. 2012;52(1-2):83-95. PMID: 23697217

Deree J, Martins JO, Melbostad H, et al. Insights into the regulation of TNF-alpha production in human mononuclear cells: the effects of non-specific phosphodiesterase inhibition. Clinics (Sao Paulo). 2008 Jun;63(3):321-8. PMID: 18568240.

Marques LJ, Zheng L, Poulakis N, et al. Pentoxifylline inhibits TNF-alpha production from human alveolar macrophages. Am J Respir Crit Care Med. 1999 Feb;159(2):508-11. PMID: 9927365.

Ward A, Clissold SP. Pentoxifylline. A review of its pharmacodynamic and pharmacokinetic properties, and its therapeutic efficacy. Drugs. 1987 Jul;34(1):50-97. PMID: 3308412.

" Xn Not dangerous goods.

LKT P7033 Primaquine Phosphate 5 g 54.6 Alters membrane permeability, prevents transport vesicle formation in parasites. N4-(6-Methoxy-8-quinolinyl)-1,4-pentanediamine diphosphate Primaquine diphosphate 63-45-6 ≥98% (titration) 455.29 C15H21N3O 2H3PO4 CC(CCCN)NC1=C2C(=CC(=C1)OC)C=CC=N2.OP(=O)(O)O.OP(=O)(O)O Ambient Ambient Soluble in water (66 mg/mL). "Basso LG, Rodrigues RZ, Naal RM, et al. Effects of the antimalarial drug primaquine on the dynamic structure of lipid model membranes. Biochim Biophys Acta. 2011 Jan;1808(1):55-64. PMID: 20713019.

Hiebsch RR, Raub TJ, Wattenberg BW. Primaquine blocks transport by inhibiting the formation of functional transport vesicles. Studies in a cell-free assay of protein transport through the Golgi apparatus. J Biol Chem. 1991 Oct 25;266(30):20323-8. PMID: 1657920.

" T "UN number: 2811     Class: 6.1     Packing Group: III

Proper shipping name: Toxic solid, organic, n.o.s. (Primaquine phosphate)

Marine pollutant: No     Poison Inhalation Hazard: No"

LKT P7033 Primaquine Phosphate 10 g 87.2 Alters membrane permeability, prevents transport vesicle formation in parasites. N4-(6-Methoxy-8-quinolinyl)-1,4-pentanediamine diphosphate Primaquine diphosphate 63-45-6 ≥98% (titration) 455.29 C15H21N3O 2H3PO4 CC(CCCN)NC1=C2C(=CC(=C1)OC)C=CC=N2.OP(=O)(O)O.OP(=O)(O)O Ambient Ambient Soluble in water (66 mg/mL). "Basso LG, Rodrigues RZ, Naal RM, et al. Effects of the antimalarial drug primaquine on the dynamic structure of lipid model membranes. Biochim Biophys Acta. 2011 Jan;1808(1):55-64. PMID: 20713019.

Hiebsch RR, Raub TJ, Wattenberg BW. Primaquine blocks transport by inhibiting the formation of functional transport vesicles. Studies in a cell-free assay of protein transport through the Golgi apparatus. J Biol Chem. 1991 Oct 25;266(30):20323-8. PMID: 1657920.

" T "UN number: 2811     Class: 6.1     Packing Group: III

Proper shipping name: Toxic solid, organic, n.o.s. (Primaquine phosphate)

Marine pollutant: No     Poison Inhalation Hazard: No"

LKT P7033 Primaquine Phosphate 50 g 294 Alters membrane permeability, prevents transport vesicle formation in parasites. N4-(6-Methoxy-8-quinolinyl)-1,4-pentanediamine diphosphate Primaquine diphosphate 63-45-6 ≥98% (titration) 455.29 C15H21N3O 2H3PO4 CC(CCCN)NC1=C2C(=CC(=C1)OC)C=CC=N2.OP(=O)(O)O.OP(=O)(O)O Ambient Ambient Soluble in water (66 mg/mL). "Basso LG, Rodrigues RZ, Naal RM, et al. Effects of the antimalarial drug primaquine on the dynamic structure of lipid model membranes. Biochim Biophys Acta. 2011 Jan;1808(1):55-64. PMID: 20713019.

Hiebsch RR, Raub TJ, Wattenberg BW. Primaquine blocks transport by inhibiting the formation of functional transport vesicles. Studies in a cell-free assay of protein transport through the Golgi apparatus. J Biol Chem. 1991 Oct 25;266(30):20323-8. PMID: 1657920.

" T "UN number: 2811     Class: 6.1     Packing Group: III

Proper shipping name: Toxic solid, organic, n.o.s. (Primaquine phosphate)

Marine pollutant: No     Poison Inhalation Hazard: No"

LKT P1760 Peptide T 1 mg 104.9 Peptide fragment of HIV-1 gp120. "N-(N-(N2-(N-(N-(N-(N-L-alanyl-L- seryl)-L-thronyl)-L-threonyl)-L-threonyl)-L-asparaginyl)-L-tyrosyl)-L-Threonine

" 106362-32-7 ≥98% 857.86 C35H55N9O16 CC(C(C(=O)NC(C(C)O)C(=O)NC(C(C)O)C(=O)NC(CC(=O)N)C(=O)NC(CC1=CC=C(C=C1)O)C(=O)NC(C(C)O)C(=O)O)NC(=O)C(CO)NC(=O)C(C)N)O Ambient -20°C "Paoletti I, De Gregorio V, Baroni A, et al. Amygdalin analogues inhibit IFN-γ signalling and reduce the inflammatory response in human epidermal keratinocytes. Inflammation. 2013 Dec;36(6):1316-26. PMID: 23933845.

D'ursi A, Caliendo G, Perissutti E, et al. Conformation-activity relationship of peptide T and new pseudocyclic hexapeptide analogs. J Pept Sci. 2007 Jun;13(6):413-21. PMID: 17486694.

Polianova MT, Ruscetti FW, Pert CB, et al. Chemokine receptor-5 (CCR5) is a receptor for the HIV entry inhibitor peptide T (DAPTA). Antiviral Res. 2005 Aug;67(2):83-92. PMID: 16002156.

Ruff MR, Melendez-Guerrero LM, Yang QE, et al. Peptide T inhibits HIV-1 infection mediated by the chemokine receptor-5 (CCR5). Antiviral Res. 2001 Oct;52(1):63-75. PMID: 11530189.

Heseltine PN, Goodkin K, Atkinson JH, et al. Randomized double-blind placebo-controlled trial of peptide T for HIV-associated cognitive impairment. Arch Neurol. 1998 Jan;55(1):41-51. PMID: 9443710.

"

LKT P7023 Pregnenolone 5 g 43.5 Endogenous precursor to all steroid hormones; TRPM3 agonist, NMDA potentiator, GABA-A negative allosteric modulator. (3β)-3-Hydroxypregn-5-en-20-one 145-13-1 ≥98% 316.48 C21H32O2 CC(=O)C1CCC2C1(CCC3C2CC=C4C3(CCC(C4)O)C)C Ambient Ambient Sparingly soluble in water. Soluble in ethyl acetate (1:1), acetone (0.006g/mL) and ethanol (.010g/mL). "Kostakis E, Smith C, Jang MK, et al. The neuroactive steroid pregnenolone sulfate stimulates trafficking of functional N-methyl D-aspartate receptors to the cell surface via a noncanonical, G protein, and Ca2+-dependent mechanism. Mol Pharmacol. 2013 Aug;84(2):261-74. PMID: 23716622.

Marx CE, Bradford DW, Hamer RM, et al. Pregnenolone as a novel therapeutic candidate in schizophrenia: emerging preclinical and clinical evidence. Neuroscience. 2011 Sep 15;191:78-90. PMID: 21756978.

Wagner TF, Loch S, Lambert S, et al. Transient receptor potential M3 channels are ionotropic steroid receptors in pancreatic beta cells. Nat Cell Biol. 2008 Dec;10(12):1421-30. PMID: 18978782.

Majewska MD, Mienville JM, Vicini S. Neurosteroid pregnenolone sulfate antagonizes electrophysiological responses to GABA in neurons. Neurosci Lett. 1988 Aug 1;90(3):279-84. PMID: 3138576.

" Not dangerous goods.

LKT P7023 Pregnenolone 25 g 122.3 Endogenous precursor to all steroid hormones; TRPM3 agonist, NMDA potentiator, GABA-A negative allosteric modulator. (3β)-3-Hydroxypregn-5-en-20-one 145-13-1 ≥98% 316.48 C21H32O2 CC(=O)C1CCC2C1(CCC3C2CC=C4C3(CCC(C4)O)C)C Ambient Ambient Sparingly soluble in water. Soluble in ethyl acetate (1:1), acetone (0.006g/mL) and ethanol (.010g/mL). "Kostakis E, Smith C, Jang MK, et al. The neuroactive steroid pregnenolone sulfate stimulates trafficking of functional N-methyl D-aspartate receptors to the cell surface via a noncanonical, G protein, and Ca2+-dependent mechanism. Mol Pharmacol. 2013 Aug;84(2):261-74. PMID: 23716622.

Marx CE, Bradford DW, Hamer RM, et al. Pregnenolone as a novel therapeutic candidate in schizophrenia: emerging preclinical and clinical evidence. Neuroscience. 2011 Sep 15;191:78-90. PMID: 21756978.

Wagner TF, Loch S, Lambert S, et al. Transient receptor potential M3 channels are ionotropic steroid receptors in pancreatic beta cells. Nat Cell Biol. 2008 Dec;10(12):1421-30. PMID: 18978782.

Majewska MD, Mienville JM, Vicini S. Neurosteroid pregnenolone sulfate antagonizes electrophysiological responses to GABA in neurons. Neurosci Lett. 1988 Aug 1;90(3):279-84. PMID: 3138576.

" Not dangerous goods.

LKT P7023 Pregnenolone 100 g 376.1 Endogenous precursor to all steroid hormones; TRPM3 agonist, NMDA potentiator, GABA-A negative allosteric modulator. (3β)-3-Hydroxypregn-5-en-20-one 145-13-1 ≥98% 316.48 C21H32O2 CC(=O)C1CCC2C1(CCC3C2CC=C4C3(CCC(C4)O)C)C Ambient Ambient Sparingly soluble in water. Soluble in ethyl acetate (1:1), acetone (0.006g/mL) and ethanol (.010g/mL). "Kostakis E, Smith C, Jang MK, et al. The neuroactive steroid pregnenolone sulfate stimulates trafficking of functional N-methyl D-aspartate receptors to the cell surface via a noncanonical, G protein, and Ca2+-dependent mechanism. Mol Pharmacol. 2013 Aug;84(2):261-74. PMID: 23716622.

Marx CE, Bradford DW, Hamer RM, et al. Pregnenolone as a novel therapeutic candidate in schizophrenia: emerging preclinical and clinical evidence. Neuroscience. 2011 Sep 15;191:78-90. PMID: 21756978.

Wagner TF, Loch S, Lambert S, et al. Transient receptor potential M3 channels are ionotropic steroid receptors in pancreatic beta cells. Nat Cell Biol. 2008 Dec;10(12):1421-30. PMID: 18978782.

Majewska MD, Mienville JM, Vicini S. Neurosteroid pregnenolone sulfate antagonizes electrophysiological responses to GABA in neurons. Neurosci Lett. 1988 Aug 1;90(3):279-84. PMID: 3138576.

" Not dangerous goods.

LKT P1761 Pepstatin 5 mg 53 Aspartyl protease inhibitor. "L-Alaninamide, N-(3-methyl-1-oxobutyl)-L-valyl-(3S,4S)-4-

amino-3-hydroxy-6-methylheptanoyl-N-((1S)-1-((1S)-2-carboxy-1-hydroxyethyl)-3-methylbutyl)-" Pepstatin A 26305-03-3 ≥98% 685.89 C34H63N5O9 CC(C)CC(C(CC(=O)O)O)NC(=O)C(C)NC(=O)CC(C(CC(C)C)NC(=O)C(C(C)C)NC(=O)C(C(C)C)NC(=O)CC(C)C)O Ambient 4°C Soluble in methanol, ethanol or DMSO. "Marciniszyn J Jr, Hartsuck JA, Tang J. Mode of inhibition of acid proteases by pepstatin. J Biol Chem. 1976 Nov 25;251(22):7088-94. PMID: 993206.

Umezawa H, Aoyagi T, Morishima H, et al. Pepstatin, a new pepsin inhibitor produced by Actinomycetes. J Antibiot (Tokyo). 1970 May;23(5):259-62. PMID: 4912600.

" Not dangerous goods.

LKT P1761 Pepstatin 25 mg 142.7 Aspartyl protease inhibitor. "L-Alaninamide, N-(3-methyl-1-oxobutyl)-L-valyl-(3S,4S)-4-

amino-3-hydroxy-6-methylheptanoyl-N-((1S)-1-((1S)-2-carboxy-1-hydroxyethyl)-3-methylbutyl)-" Pepstatin A 26305-03-3 ≥98% 685.89 C34H63N5O9 CC(C)CC(C(CC(=O)O)O)NC(=O)C(C)NC(=O)CC(C(CC(C)C)NC(=O)C(C(C)C)NC(=O)C(C(C)C)NC(=O)CC(C)C)O Ambient 4°C Soluble in methanol, ethanol or DMSO. "Marciniszyn J Jr, Hartsuck JA, Tang J. Mode of inhibition of acid proteases by pepstatin. J Biol Chem. 1976 Nov 25;251(22):7088-94. PMID: 993206.

Umezawa H, Aoyagi T, Morishima H, et al. Pepstatin, a new pepsin inhibitor produced by Actinomycetes. J Antibiot (Tokyo). 1970 May;23(5):259-62. PMID: 4912600.

" Not dangerous goods.

LKT P1761 Pepstatin 100 mg 475.7 Aspartyl protease inhibitor. "L-Alaninamide, N-(3-methyl-1-oxobutyl)-L-valyl-(3S,4S)-4-

amino-3-hydroxy-6-methylheptanoyl-N-((1S)-1-((1S)-2-carboxy-1-hydroxyethyl)-3-methylbutyl)-" Pepstatin A 26305-03-3 ≥98% 685.89 C34H63N5O9 CC(C)CC(C(CC(=O)O)O)NC(=O)C(C)NC(=O)CC(C(CC(C)C)NC(=O)C(C(C)C)NC(=O)C(C(C)C)NC(=O)CC(C)C)O Ambient 4°C Soluble in methanol, ethanol or DMSO. "Marciniszyn J Jr, Hartsuck JA, Tang J. Mode of inhibition of acid proteases by pepstatin. J Biol Chem. 1976 Nov 25;251(22):7088-94. PMID: 993206.

Umezawa H, Aoyagi T, Morishima H, et al. Pepstatin, a new pepsin inhibitor produced by Actinomycetes. J Antibiot (Tokyo). 1970 May;23(5):259-62. PMID: 4912600.

" Not dangerous goods.

LKT P7022 Pressinoic Acid 1 mg 60 Peptide, N-terminal vasopressin analog. 35748-51-7 ≥95% 774.08 C33H42N8O10S2 C1C(C(=O)NC(C(=O)NC(C(=O)NC(C(=O)NC(C(=O)NC(CSS1)C(=O)O)CC(=O)N)CCC(=O)N)CC2=CC=CC=C2)CC3=CC=C(C=C3)O)N Ambient -20°C "Torres BA, Johnson HM. Arginine vasopressin (AVP) replacement of helper cell requirement in IFN-gamma production. Evidence for a novel AVP receptor on mouse lymphocytes. J Immunol. 1988 Apr 1;140(7):2179-83. PMID: 2965181.

Langs DA, Smith GD, Stezowski JJ, et al. Structure of pressinoic acid: the cyclic moiety of vasopressin. Science. 1986 Jun 6;232(4755):1240-2. PMID: 3704648.

" Not dangerous goods.

LKT P7022 Pressinoic Acid 2 mg 101.9 Peptide, N-terminal vasopressin analog. 35748-51-7 ≥95% 774.08 C33H42N8O10S2 C1C(C(=O)NC(C(=O)NC(C(=O)NC(C(=O)NC(C(=O)NC(CSS1)C(=O)O)CC(=O)N)CCC(=O)N)CC2=CC=CC=C2)CC3=CC=C(C=C3)O)N Ambient -20°C "Torres BA, Johnson HM. Arginine vasopressin (AVP) replacement of helper cell requirement in IFN-gamma production. Evidence for a novel AVP receptor on mouse lymphocytes. J Immunol. 1988 Apr 1;140(7):2179-83. PMID: 2965181.

Langs DA, Smith GD, Stezowski JJ, et al. Structure of pressinoic acid: the cyclic moiety of vasopressin. Science. 1986 Jun 6;232(4755):1240-2. PMID: 3704648.

" Not dangerous goods.

LKT P7022 Pressinoic Acid 5 mg 180 Peptide, N-terminal vasopressin analog. 35748-51-7 ≥95% 774.08 C33H42N8O10S2 C1C(C(=O)NC(C(=O)NC(C(=O)NC(C(=O)NC(C(=O)NC(CSS1)C(=O)O)CC(=O)N)CCC(=O)N)CC2=CC=CC=C2)CC3=CC=C(C=C3)O)N Ambient -20°C "Torres BA, Johnson HM. Arginine vasopressin (AVP) replacement of helper cell requirement in IFN-gamma production. Evidence for a novel AVP receptor on mouse lymphocytes. J Immunol. 1988 Apr 1;140(7):2179-83. PMID: 2965181.

Langs DA, Smith GD, Stezowski JJ, et al. Structure of pressinoic acid: the cyclic moiety of vasopressin. Science. 1986 Jun 6;232(4755):1240-2. PMID: 3704648.

" Not dangerous goods.

LKT P7021 Prednisone Acetate 1 g 41.8 Synthetic prednisolone prodrug; glucocorticoid agonist. 17,21-Dihydroxypregna-1,4-diene-3,11,20-trione acetate Prednisone 21-acetate; Pred Forte 125-10-0 ≥98% 400.46 C23H28O6 CC(=O)OCC(=O)C1(CCC2C1(CC(=O)C3C2CCC4=CC(=O)C=CC34C)C)O Incompatable with strong oxidizing agents. Ambient Ambient Insoluble in water.  Slightly soluble in ethanol. "Hoy SM. Bendamustine: a review of its use in the management of chronic lymphocytic leukaemia, rituximab-refractory indolent non-Hodgkin's lymphoma and multiple myeloma. Drugs. 2012 Oct 1;72(14):1929-50. PMID: 22950536.

Clarke L, Kirwan J. Efficacy, safety and mechanism of action of modified-release prednisone in rheumatoid arthritis. Ther Adv Musculoskelet Dis. 2012 Jun;4(3):159-66. PMID: 22850902.

He Z, Ostrowski RP, Sun X, et al. CHOP silencing reduces acute brain injury in the rat model of subarachnoid hemorrhage. Stroke. 2012 Feb;43(2):484-90. PMID: 22180248.

Manns MP, Strassburg CP. Therapeutic strategies for autoimmune hepatitis. Dig Dis. 2011;29(4):411-5. PMID: 21894012.

" Not dangerous goods.

LKT P7021 Prednisone Acetate 5 g 138.9 Synthetic prednisolone prodrug; glucocorticoid agonist. 17,21-Dihydroxypregna-1,4-diene-3,11,20-trione acetate Prednisone 21-acetate; Pred Forte 125-10-0 ≥98% 400.46 C23H28O6 CC(=O)OCC(=O)C1(CCC2C1(CC(=O)C3C2CCC4=CC(=O)C=CC34C)C)O Incompatable with strong oxidizing agents. Ambient Ambient Insoluble in water.  Slightly soluble in ethanol. "Hoy SM. Bendamustine: a review of its use in the management of chronic lymphocytic leukaemia, rituximab-refractory indolent non-Hodgkin's lymphoma and multiple myeloma. Drugs. 2012 Oct 1;72(14):1929-50. PMID: 22950536.

Clarke L, Kirwan J. Efficacy, safety and mechanism of action of modified-release prednisone in rheumatoid arthritis. Ther Adv Musculoskelet Dis. 2012 Jun;4(3):159-66. PMID: 22850902.

He Z, Ostrowski RP, Sun X, et al. CHOP silencing reduces acute brain injury in the rat model of subarachnoid hemorrhage. Stroke. 2012 Feb;43(2):484-90. PMID: 22180248.

Manns MP, Strassburg CP. Therapeutic strategies for autoimmune hepatitis. Dig Dis. 2011;29(4):411-5. PMID: 21894012.

" Not dangerous goods.

LKT P7021 Prednisone Acetate 25 g 485.4 Synthetic prednisolone prodrug; glucocorticoid agonist. 17,21-Dihydroxypregna-1,4-diene-3,11,20-trione acetate Prednisone 21-acetate; Pred Forte 125-10-0 ≥98% 400.46 C23H28O6 CC(=O)OCC(=O)C1(CCC2C1(CC(=O)C3C2CCC4=CC(=O)C=CC34C)C)O Incompatable with strong oxidizing agents. Ambient Ambient Insoluble in water.  Slightly soluble in ethanol. "Hoy SM. Bendamustine: a review of its use in the management of chronic lymphocytic leukaemia, rituximab-refractory indolent non-Hodgkin's lymphoma and multiple myeloma. Drugs. 2012 Oct 1;72(14):1929-50. PMID: 22950536.

Clarke L, Kirwan J. Efficacy, safety and mechanism of action of modified-release prednisone in rheumatoid arthritis. Ther Adv Musculoskelet Dis. 2012 Jun;4(3):159-66. PMID: 22850902.

He Z, Ostrowski RP, Sun X, et al. CHOP silencing reduces acute brain injury in the rat model of subarachnoid hemorrhage. Stroke. 2012 Feb;43(2):484-90. PMID: 22180248.

Manns MP, Strassburg CP. Therapeutic strategies for autoimmune hepatitis. Dig Dis. 2011;29(4):411-5. PMID: 21894012.

" Not dangerous goods.

LKT P7020 Prednisone 1 g 34.8 Synthetic prednisolone prodrug; glucocorticoid agonist. 17,21-Dihydroxypregna-1,4-diene-3,11,20-trione Ancortone; Colisone; Decortin; Hostacortine; Orasone; Paracort; Sone; Ultracorten 53-03-2 ≥98% 358.43 C21H26O5 CC12CC(=O)C3C(C1CCC2(C(=O)CO)O)CCC4=CC(=O)C=CC34C Ambient Ambient Slightly soluble in water and ethanol (6.5 mg/mL). "Hoy SM. Bendamustine: a review of its use in the management of chronic lymphocytic leukaemia, rituximab-refractory indolent non-Hodgkin's lymphoma and multiple myeloma. Drugs. 2012 Oct 1;72(14):1929-50. PMID: 22950536.

Clarke L, Kirwan J. Efficacy, safety and mechanism of action of modified-release prednisone in rheumatoid arthritis. Ther Adv Musculoskelet Dis. 2012 Jun;4(3):159-66. PMID: 22850902.

He Z, Ostrowski RP, Sun X, et al. CHOP silencing reduces acute brain injury in the rat model of subarachnoid hemorrhage. Stroke. 2012 Feb;43(2):484-90. PMID: 22180248.

Manns MP, Strassburg CP. Therapeutic strategies for autoimmune hepatitis. Dig Dis. 2011;29(4):411-5. PMID: 21894012.

" Repr. Not dangerous goods.

LKT P7020 Prednisone 5 g 127.1 Synthetic prednisolone prodrug; glucocorticoid agonist. 17,21-Dihydroxypregna-1,4-diene-3,11,20-trione Ancortone; Colisone; Decortin; Hostacortine; Orasone; Paracort; Sone; Ultracorten 53-03-2 ≥98% 358.43 C21H26O5 CC12CC(=O)C3C(C1CCC2(C(=O)CO)O)CCC4=CC(=O)C=CC34C Ambient Ambient Slightly soluble in water and ethanol (6.5 mg/mL). "Hoy SM. Bendamustine: a review of its use in the management of chronic lymphocytic leukaemia, rituximab-refractory indolent non-Hodgkin's lymphoma and multiple myeloma. Drugs. 2012 Oct 1;72(14):1929-50. PMID: 22950536.

Clarke L, Kirwan J. Efficacy, safety and mechanism of action of modified-release prednisone in rheumatoid arthritis. Ther Adv Musculoskelet Dis. 2012 Jun;4(3):159-66. PMID: 22850902.

He Z, Ostrowski RP, Sun X, et al. CHOP silencing reduces acute brain injury in the rat model of subarachnoid hemorrhage. Stroke. 2012 Feb;43(2):484-90. PMID: 22180248.

Manns MP, Strassburg CP. Therapeutic strategies for autoimmune hepatitis. Dig Dis. 2011;29(4):411-5. PMID: 21894012.

" Repr. Not dangerous goods.

LKT P7020 Prednisone 25 g 462.1 Synthetic prednisolone prodrug; glucocorticoid agonist. 17,21-Dihydroxypregna-1,4-diene-3,11,20-trione Ancortone; Colisone; Decortin; Hostacortine; Orasone; Paracort; Sone; Ultracorten 53-03-2 ≥98% 358.43 C21H26O5 CC12CC(=O)C3C(C1CCC2(C(=O)CO)O)CCC4=CC(=O)C=CC34C Ambient Ambient Slightly soluble in water and ethanol (6.5 mg/mL). "Hoy SM. Bendamustine: a review of its use in the management of chronic lymphocytic leukaemia, rituximab-refractory indolent non-Hodgkin's lymphoma and multiple myeloma. Drugs. 2012 Oct 1;72(14):1929-50. PMID: 22950536.

Clarke L, Kirwan J. Efficacy, safety and mechanism of action of modified-release prednisone in rheumatoid arthritis. Ther Adv Musculoskelet Dis. 2012 Jun;4(3):159-66. PMID: 22850902.

He Z, Ostrowski RP, Sun X, et al. CHOP silencing reduces acute brain injury in the rat model of subarachnoid hemorrhage. Stroke. 2012 Feb;43(2):484-90. PMID: 22180248.

Manns MP, Strassburg CP. Therapeutic strategies for autoimmune hepatitis. Dig Dis. 2011;29(4):411-5. PMID: 21894012.

" Repr. Not dangerous goods.

LKT P7012 Prednisolone Sodium Phosphate 5 g 214 Water-soluble cortisol derivative; glucocorticoid agonist. 11β,17,21-Trihydroxypregna-1,4-diene-3,20-dione 21-(disodium phosphate) Hydeltrasol; Prednisolone 21-phosphate disodium 125-02-0 ≥98% 484.39 C21H27Na2O8P CC12CC(C3C(C1CCC2(C(=O)COP(=O)([O-])[O-])O)CCC4=CC(=O)C=CC34C)O.[Na+].[Na+] Slightly hygroscopic Ambient Ambient Soluble in water (250 mg/ mL), methanol (77 mg/mL) and ethanol. "Frisullo G, Nociti V, Iorio R, et al. Glucocorticoid treatment reduces T-bet and pSTAT1 expression in mononuclear cells from relapsing remitting multiple sclerosis patients. Clin Immunol. 2007 Sep;124(3):284-93. PMID: 17627892.

Fisher I, Abraham D, Bouri K, et al. Prednisolone-induced changes in dystrophic skeletal muscle. FASEB J. 2005 May;19(7):834-6. Erratum in: FASEB J. 2005 May;19(7):1 p following 836. Hoffmann, Eric P [corrected to Hoffman, Eric P]. PMID: 15734791.

Davis M, Williams R, Chakraborty J, et al. Prednisone or prednisolone for the treatment of chronic active hepatitis? A comparison of plasma availability. Br J Clin Pharmacol. 1978 Jun;5(6):501-5. PMID: 656293.

" Repr. Not dangerous goods.

LKT P7012 Prednisolone Sodium Phosphate 10 g 356.7 Water-soluble cortisol derivative; glucocorticoid agonist. 11β,17,21-Trihydroxypregna-1,4-diene-3,20-dione 21-(disodium phosphate) Hydeltrasol; Prednisolone 21-phosphate disodium 125-02-0 ≥98% 484.39 C21H27Na2O8P CC12CC(C3C(C1CCC2(C(=O)COP(=O)([O-])[O-])O)CCC4=CC(=O)C=CC34C)O.[Na+].[Na+] Slightly hygroscopic Ambient Ambient Soluble in water (250 mg/ mL), methanol (77 mg/mL) and ethanol. "Frisullo G, Nociti V, Iorio R, et al. Glucocorticoid treatment reduces T-bet and pSTAT1 expression in mononuclear cells from relapsing remitting multiple sclerosis patients. Clin Immunol. 2007 Sep;124(3):284-93. PMID: 17627892.

Fisher I, Abraham D, Bouri K, et al. Prednisolone-induced changes in dystrophic skeletal muscle. FASEB J. 2005 May;19(7):834-6. Erratum in: FASEB J. 2005 May;19(7):1 p following 836. Hoffmann, Eric P [corrected to Hoffman, Eric P]. PMID: 15734791.

Davis M, Williams R, Chakraborty J, et al. Prednisone or prednisolone for the treatment of chronic active hepatitis? A comparison of plasma availability. Br J Clin Pharmacol. 1978 Jun;5(6):501-5. PMID: 656293.

" Repr. Not dangerous goods.

LKT P7012 Prednisolone Sodium Phosphate 25 g 686.3 Water-soluble cortisol derivative; glucocorticoid agonist. 11β,17,21-Trihydroxypregna-1,4-diene-3,20-dione 21-(disodium phosphate) Hydeltrasol; Prednisolone 21-phosphate disodium 125-02-0 ≥98% 484.39 C21H27Na2O8P CC12CC(C3C(C1CCC2(C(=O)COP(=O)([O-])[O-])O)CCC4=CC(=O)C=CC34C)O.[Na+].[Na+] Slightly hygroscopic Ambient Ambient Soluble in water (250 mg/ mL), methanol (77 mg/mL) and ethanol. "Frisullo G, Nociti V, Iorio R, et al. Glucocorticoid treatment reduces T-bet and pSTAT1 expression in mononuclear cells from relapsing remitting multiple sclerosis patients. Clin Immunol. 2007 Sep;124(3):284-93. PMID: 17627892.

Fisher I, Abraham D, Bouri K, et al. Prednisolone-induced changes in dystrophic skeletal muscle. FASEB J. 2005 May;19(7):834-6. Erratum in: FASEB J. 2005 May;19(7):1 p following 836. Hoffmann, Eric P [corrected to Hoffman, Eric P]. PMID: 15734791.

Davis M, Williams R, Chakraborty J, et al. Prednisone or prednisolone for the treatment of chronic active hepatitis? A comparison of plasma availability. Br J Clin Pharmacol. 1978 Jun;5(6):501-5. PMID: 656293.

" Repr. Not dangerous goods.

LKT P6977 Pyr-GR-pNA 1 mg 90.1 Fluorogenic substrate used to measure serine protease activity. Pyr-Gly-Arg-pNA ≥98% 462.5 C19H26N8O6 Ambient -20°C "Rajapakse S, Ogiwara K, Takano N, et al. Biochemical characterization of human kallikrein 8 and its possible involvement in the degradation of extracellular matrix proteins. FEBS Lett. 2005 Dec 19;579(30):6879-84. PMID: 16337200.

Matsui N, Okikawa T, Imajo N, et al. Enzymatic measurement of tryptase-like protease release from isolated perfused guinea pig heart during ischemia-reperfusion. Biol Pharm Bull. 2005 Nov;28(11):2149-51. PMID: 16272708.

"

LKT P6977 Pyr-GR-pNA 10 mg 300.1 Fluorogenic substrate used to measure serine protease activity. Pyr-Gly-Arg-pNA ≥98% 462.5 C19H26N8O6 Ambient -20°C "Rajapakse S, Ogiwara K, Takano N, et al. Biochemical characterization of human kallikrein 8 and its possible involvement in the degradation of extracellular matrix proteins. FEBS Lett. 2005 Dec 19;579(30):6879-84. PMID: 16337200.

Matsui N, Okikawa T, Imajo N, et al. Enzymatic measurement of tryptase-like protease release from isolated perfused guinea pig heart during ischemia-reperfusion. Biol Pharm Bull. 2005 Nov;28(11):2149-51. PMID: 16272708.

"

LKT P1762 Peptide YY, pig 1 mg 516.1 Endogenous neuropeptide, involved in enteric movement and feeding behavior; Y1/2 agonist. Peptide tyrosine tyrosine, PYY 81858-94-8 ≥98% 4240.7 C190H288N54O57 Ambient -20°C "Wong IP, Driessler F, Khor EC, et al. Peptide YY regulates bone remodeling in mice: a link between gut and skeletal biology. PLoS One. 2012;7(7):e40038. PMID: 22792209.

Shi YC, Hämmerle CM, Lee IC, et al. Adult-onset PYY overexpression in mice reduces food intake and increases lipogenic capacity. Neuropeptides. 2012 Aug;46(4):173-82. PMID: 22575886.

Tough IR, Forbes S, Tolhurst R, et al. Endogenous peptide YY and neuropeptide Y inhibit colonic ion transport, contractility and transit differentially via Y1 and Y2 receptors. Br J Pharmacol. 2011 Sep;164(2b):471-84. PMID: 21457230.

" Not dangerous goods.

LKT P1762 Peptide YY, pig 2 mg 876.2 Endogenous neuropeptide, involved in enteric movement and feeding behavior; Y1/2 agonist. Peptide tyrosine tyrosine, PYY 81858-94-8 ≥98% 4240.7 C190H288N54O57 Ambient -20°C "Wong IP, Driessler F, Khor EC, et al. Peptide YY regulates bone remodeling in mice: a link between gut and skeletal biology. PLoS One. 2012;7(7):e40038. PMID: 22792209.

Shi YC, Hämmerle CM, Lee IC, et al. Adult-onset PYY overexpression in mice reduces food intake and increases lipogenic capacity. Neuropeptides. 2012 Aug;46(4):173-82. PMID: 22575886.

Tough IR, Forbes S, Tolhurst R, et al. Endogenous peptide YY and neuropeptide Y inhibit colonic ion transport, contractility and transit differentially via Y1 and Y2 receptors. Br J Pharmacol. 2011 Sep;164(2b):471-84. PMID: 21457230.

" Not dangerous goods.

LKT P1762 Peptide YY, pig 5 mg 1548.3 Endogenous neuropeptide, involved in enteric movement and feeding behavior; Y1/2 agonist. Peptide tyrosine tyrosine, PYY 81858-94-8 ≥98% 4240.7 C190H288N54O57 Ambient -20°C "Wong IP, Driessler F, Khor EC, et al. Peptide YY regulates bone remodeling in mice: a link between gut and skeletal biology. PLoS One. 2012;7(7):e40038. PMID: 22792209.

Shi YC, Hämmerle CM, Lee IC, et al. Adult-onset PYY overexpression in mice reduces food intake and increases lipogenic capacity. Neuropeptides. 2012 Aug;46(4):173-82. PMID: 22575886.

Tough IR, Forbes S, Tolhurst R, et al. Endogenous peptide YY and neuropeptide Y inhibit colonic ion transport, contractility and transit differentially via Y1 and Y2 receptors. Br J Pharmacol. 2011 Sep;164(2b):471-84. PMID: 21457230.

" Not dangerous goods.

LKT P1763 Peptide YY, human 1 mg 516.1 Endogenous neuropeptide, involved in enteric movement and feeding behavior; Y1/2 agonist. Peptide tyrosine tyrosine, PYY 118997-30-1 ≥98% 4309.8 C194H295N55O57 Ambient -20°C "Wong IP, Driessler F, Khor EC, et al. Peptide YY regulates bone remodeling in mice: a link between gut and skeletal biology. PLoS One. 2012;7(7):e40038. PMID: 22792209.

Shi YC, Hämmerle CM, Lee IC, et al. Adult-onset PYY overexpression in mice reduces food intake and increases lipogenic capacity. Neuropeptides. 2012 Aug;46(4):173-82. PMID: 22575886.

Tough IR, Forbes S, Tolhurst R, et al. Endogenous peptide YY and neuropeptide Y inhibit colonic ion transport, contractility and transit differentially via Y1 and Y2 receptors. Br J Pharmacol. 2011 Sep;164(2b):471-84. PMID: 21457230.

" Not dangerous goods.

LKT P1763 Peptide YY, human 2 mg 876.2 Endogenous neuropeptide, involved in enteric movement and feeding behavior; Y1/2 agonist. Peptide tyrosine tyrosine, PYY 118997-30-1 ≥98% 4309.8 C194H295N55O57 Ambient -20°C "Wong IP, Driessler F, Khor EC, et al. Peptide YY regulates bone remodeling in mice: a link between gut and skeletal biology. PLoS One. 2012;7(7):e40038. PMID: 22792209.

Shi YC, Hämmerle CM, Lee IC, et al. Adult-onset PYY overexpression in mice reduces food intake and increases lipogenic capacity. Neuropeptides. 2012 Aug;46(4):173-82. PMID: 22575886.

Tough IR, Forbes S, Tolhurst R, et al. Endogenous peptide YY and neuropeptide Y inhibit colonic ion transport, contractility and transit differentially via Y1 and Y2 receptors. Br J Pharmacol. 2011 Sep;164(2b):471-84. PMID: 21457230.

" Not dangerous goods.

LKT P1763 Peptide YY, human 5 mg 1548.3 Endogenous neuropeptide, involved in enteric movement and feeding behavior; Y1/2 agonist. Peptide tyrosine tyrosine, PYY 118997-30-1 ≥98% 4309.8 C194H295N55O57 Ambient -20°C "Wong IP, Driessler F, Khor EC, et al. Peptide YY regulates bone remodeling in mice: a link between gut and skeletal biology. PLoS One. 2012;7(7):e40038. PMID: 22792209.

Shi YC, Hämmerle CM, Lee IC, et al. Adult-onset PYY overexpression in mice reduces food intake and increases lipogenic capacity. Neuropeptides. 2012 Aug;46(4):173-82. PMID: 22575886.

Tough IR, Forbes S, Tolhurst R, et al. Endogenous peptide YY and neuropeptide Y inhibit colonic ion transport, contractility and transit differentially via Y1 and Y2 receptors. Br J Pharmacol. 2011 Sep;164(2b):471-84. PMID: 21457230.

" Not dangerous goods.

LKT P1764 Pep-1 Peptide 0.5 mg 144 Cell-penetrating peptide, carries large conjugated structures across cell membranes. ≥95% 2848.23 C37H50N7O9S1 Ambient -20°C "Meloni BP, Craig AJ, Milech N, et al. The Neuroprotective Efficacy of Cell-Penetrating Peptides TAT, Penetratin, Arg-9, and Pep-1 in Glutamic Acid, Kainic Acid, and In Vitro Ischemia Injury Models Using Primary Cortical Neuronal Cultures. Cell Mol Neurobiol. 2013 Nov 9. [Epub ahead of print]. PMID: 24213248.

Thaete LG, Qu XW, Jilling T, et al. Impact of toll-like receptor 4 deficiency on the response to uterine ischemia/reperfusion in mice. Reproduction. 2013 Apr 29;145(5):517-26. PMID: 23509372.

Riehl TE, Ee X, Stenson WF. Hyaluronic acid regulates normal intestinal and colonic growth in mice. Am J Physiol Gastrointest Liver Physiol. 2012 Aug 1;303(3):G377-88. PMID: 22556141.

Bobone S, Piazzon A, Orioni B, et al. The thin line between cell-penetrating and antimicrobial peptides: the case of Pep-1 and Pep-1-K. J Pept Sci. 2011 May;17(5):335-41. PMID: 21294230.

" Not dangerous goods.

LKT P1764 Pep-1 Peptide 1 mg 245.9 Cell-penetrating peptide, carries large conjugated structures across cell membranes. ≥95% 2848.23 C37H50N7O9S1 Ambient -20°C "Meloni BP, Craig AJ, Milech N, et al. The Neuroprotective Efficacy of Cell-Penetrating Peptides TAT, Penetratin, Arg-9, and Pep-1 in Glutamic Acid, Kainic Acid, and In Vitro Ischemia Injury Models Using Primary Cortical Neuronal Cultures. Cell Mol Neurobiol. 2013 Nov 9. [Epub ahead of print]. PMID: 24213248.

Thaete LG, Qu XW, Jilling T, et al. Impact of toll-like receptor 4 deficiency on the response to uterine ischemia/reperfusion in mice. Reproduction. 2013 Apr 29;145(5):517-26. PMID: 23509372.

Riehl TE, Ee X, Stenson WF. Hyaluronic acid regulates normal intestinal and colonic growth in mice. Am J Physiol Gastrointest Liver Physiol. 2012 Aug 1;303(3):G377-88. PMID: 22556141.

Bobone S, Piazzon A, Orioni B, et al. The thin line between cell-penetrating and antimicrobial peptides: the case of Pep-1 and Pep-1-K. J Pept Sci. 2011 May;17(5):335-41. PMID: 21294230.

" Not dangerous goods.

LKT P1764 Pep-1 Peptide 2.5 mg 432 Cell-penetrating peptide, carries large conjugated structures across cell membranes. ≥95% 2848.23 C37H50N7O9S1 Ambient -20°C "Meloni BP, Craig AJ, Milech N, et al. The Neuroprotective Efficacy of Cell-Penetrating Peptides TAT, Penetratin, Arg-9, and Pep-1 in Glutamic Acid, Kainic Acid, and In Vitro Ischemia Injury Models Using Primary Cortical Neuronal Cultures. Cell Mol Neurobiol. 2013 Nov 9. [Epub ahead of print]. PMID: 24213248.

Thaete LG, Qu XW, Jilling T, et al. Impact of toll-like receptor 4 deficiency on the response to uterine ischemia/reperfusion in mice. Reproduction. 2013 Apr 29;145(5):517-26. PMID: 23509372.

Riehl TE, Ee X, Stenson WF. Hyaluronic acid regulates normal intestinal and colonic growth in mice. Am J Physiol Gastrointest Liver Physiol. 2012 Aug 1;303(3):G377-88. PMID: 22556141.

Bobone S, Piazzon A, Orioni B, et al. The thin line between cell-penetrating and antimicrobial peptides: the case of Pep-1 and Pep-1-K. J Pept Sci. 2011 May;17(5):335-41. PMID: 21294230.

" Not dangerous goods.

LKT P6959 Prothionamide 1 g 67.9 Nicotinic acid derivative; InhA inhibitor. 2-Propyl-4-pyridinecarbothioamide Protionamide; Ektebin; Tuberex; Peteha; Trevintix  14222-60-7 ≥98% 180.27 C9H12N2S CCCC1=NC=CC(=C1)C(=S)N Ambient Ambient Soluble in ethanol and methanol. Slightly soluble in ether and chloroform. Insoluble in water. "Shim TS, Jo KW. Medical Treatment of Pulmonary Multidrug-Resistant Tuberculosis. Infect Chemother. 2013 Dec;45(4):367-374. PMID: 24475350.

Wang F, Langley R, Gulten G, et al. Mechanism of thioamide drug action against tuberculosis and leprosy. J Exp Med. 2007 Jan 22;204(1):73-8. PMID: 17227913.

Fajardo TT, Guinto RS, Cellona RV, et al. A clinical trial of ethionamide and prothionamide for treatment of lepromatous leprosy. Am J Trop Med Hyg. 2006 Mar;74(3):457-61. PMID: 16525107.

" Not dangerous goods.

LKT P6959 Prothionamide 5 g 108.8 Nicotinic acid derivative; InhA inhibitor. 2-Propyl-4-pyridinecarbothioamide Protionamide; Ektebin; Tuberex; Peteha; Trevintix  14222-60-7 ≥98% 180.27 C9H12N2S CCCC1=NC=CC(=C1)C(=S)N Ambient Ambient Soluble in ethanol and methanol. Slightly soluble in ether and chloroform. Insoluble in water. "Shim TS, Jo KW. Medical Treatment of Pulmonary Multidrug-Resistant Tuberculosis. Infect Chemother. 2013 Dec;45(4):367-374. PMID: 24475350.

Wang F, Langley R, Gulten G, et al. Mechanism of thioamide drug action against tuberculosis and leprosy. J Exp Med. 2007 Jan 22;204(1):73-8. PMID: 17227913.

Fajardo TT, Guinto RS, Cellona RV, et al. A clinical trial of ethionamide and prothionamide for treatment of lepromatous leprosy. Am J Trop Med Hyg. 2006 Mar;74(3):457-61. PMID: 16525107.

" Not dangerous goods.

LKT P6959 Prothionamide 25 g 339.8 Nicotinic acid derivative; InhA inhibitor. 2-Propyl-4-pyridinecarbothioamide Protionamide; Ektebin; Tuberex; Peteha; Trevintix  14222-60-7 ≥98% 180.27 C9H12N2S CCCC1=NC=CC(=C1)C(=S)N Ambient Ambient Soluble in ethanol and methanol. Slightly soluble in ether and chloroform. Insoluble in water. "Shim TS, Jo KW. Medical Treatment of Pulmonary Multidrug-Resistant Tuberculosis. Infect Chemother. 2013 Dec;45(4):367-374. PMID: 24475350.

Wang F, Langley R, Gulten G, et al. Mechanism of thioamide drug action against tuberculosis and leprosy. J Exp Med. 2007 Jan 22;204(1):73-8. PMID: 17227913.

Fajardo TT, Guinto RS, Cellona RV, et al. A clinical trial of ethionamide and prothionamide for treatment of lepromatous leprosy. Am J Trop Med Hyg. 2006 Mar;74(3):457-61. PMID: 16525107.

" Not dangerous goods.

LKT P6958 Protopanaxatriol 5 mg 169.9 Triterpene sapogenin found in species of Panax; GABA-A/C antagonist, slow-activating delayed rectifier K+ channel blocker. 34080-08-5 ≥95% 476.73 C30H52O4 CC(=CCC[C@](C)([C@H]1CC[C@@]2([C@@H]1[C@@H](C[C@H]3[C@]2(C[C@@H]([C@@H]4[C@@]3(CC[C@@H](C4(C)C)O)C)O)C)O)C)O)C Ambient 4°C "Deb S, Chin MY, Adomat H, et al. Ginsenoside-mediated blockade of 1α,25-dihydroxyvitamin D3 inactivation in human liver and intestine in vitro. J Steroid Biochem Mol Biol. 2014 May;141:94-103. PMID: 24486455.

Lee BH, Hwang SH, Choi SH, et al. Inhibitory Effects of Ginsenoside Metabolites, Compound K and Protopanaxatriol, on GABAC Receptor-Mediated Ion Currents. Korean J Physiol Pharmacol. 2013 Apr;17(2):127-32. PMID: 23626474.

Hong SY, Kim JY, Ahn HY, et al. Panax ginseng extract rich in ginsenoside protopanaxatriol attenuates blood pressure elevation in spontaneously hypertensive rats by affecting the Akt-dependent phosphorylation of endothelial nitric oxide synthase. J Agric Food Chem. 2012 Mar 28;60(12):3086-91. PMID: 22380784.

Lee BH, Choi SH, Shin TJ, et al. Effects of Ginsenoside Metabolites on GABAA Receptor-Mediated Ion Currents. J Ginseng Res. 2012 Jan;36(1):55-60. PMID: 23717104

Han B, Meng Q, Li Q, et al. Effect of 20(S)-protopanaxatriol and its epimeric derivatives on myocardial injury induced by isoproterenol. Arzneimittelforschung. 2011;61(3):148-52. PMID: 21528638.

" None Not dangerous goods.

LKT P6958 Protopanaxatriol 10 mg 285.4 Triterpene sapogenin found in species of Panax; GABA-A/C antagonist, slow-activating delayed rectifier K+ channel blocker. 34080-08-5 ≥95% 476.73 C30H52O4 CC(=CCC[C@](C)([C@H]1CC[C@@]2([C@@H]1[C@@H](C[C@H]3[C@]2(C[C@@H]([C@@H]4[C@@]3(CC[C@@H](C4(C)C)O)C)O)C)O)C)O)C Ambient 4°C "Deb S, Chin MY, Adomat H, et al. Ginsenoside-mediated blockade of 1α,25-dihydroxyvitamin D3 inactivation in human liver and intestine in vitro. J Steroid Biochem Mol Biol. 2014 May;141:94-103. PMID: 24486455.

Lee BH, Hwang SH, Choi SH, et al. Inhibitory Effects of Ginsenoside Metabolites, Compound K and Protopanaxatriol, on GABAC Receptor-Mediated Ion Currents. Korean J Physiol Pharmacol. 2013 Apr;17(2):127-32. PMID: 23626474.

Hong SY, Kim JY, Ahn HY, et al. Panax ginseng extract rich in ginsenoside protopanaxatriol attenuates blood pressure elevation in spontaneously hypertensive rats by affecting the Akt-dependent phosphorylation of endothelial nitric oxide synthase. J Agric Food Chem. 2012 Mar 28;60(12):3086-91. PMID: 22380784.

Lee BH, Choi SH, Shin TJ, et al. Effects of Ginsenoside Metabolites on GABAA Receptor-Mediated Ion Currents. J Ginseng Res. 2012 Jan;36(1):55-60. PMID: 23717104

Han B, Meng Q, Li Q, et al. Effect of 20(S)-protopanaxatriol and its epimeric derivatives on myocardial injury induced by isoproterenol. Arzneimittelforschung. 2011;61(3):148-52. PMID: 21528638.

" None Not dangerous goods.

LKT P6958 Protopanaxatriol 25 mg 557.1 Triterpene sapogenin found in species of Panax; GABA-A/C antagonist, slow-activating delayed rectifier K+ channel blocker. 34080-08-5 ≥95% 476.73 C30H52O4 CC(=CCC[C@](C)([C@H]1CC[C@@]2([C@@H]1[C@@H](C[C@H]3[C@]2(C[C@@H]([C@@H]4[C@@]3(CC[C@@H](C4(C)C)O)C)O)C)O)C)O)C Ambient 4°C "Deb S, Chin MY, Adomat H, et al. Ginsenoside-mediated blockade of 1α,25-dihydroxyvitamin D3 inactivation in human liver and intestine in vitro. J Steroid Biochem Mol Biol. 2014 May;141:94-103. PMID: 24486455.

Lee BH, Hwang SH, Choi SH, et al. Inhibitory Effects of Ginsenoside Metabolites, Compound K and Protopanaxatriol, on GABAC Receptor-Mediated Ion Currents. Korean J Physiol Pharmacol. 2013 Apr;17(2):127-32. PMID: 23626474.

Hong SY, Kim JY, Ahn HY, et al. Panax ginseng extract rich in ginsenoside protopanaxatriol attenuates blood pressure elevation in spontaneously hypertensive rats by affecting the Akt-dependent phosphorylation of endothelial nitric oxide synthase. J Agric Food Chem. 2012 Mar 28;60(12):3086-91. PMID: 22380784.

Lee BH, Choi SH, Shin TJ, et al. Effects of Ginsenoside Metabolites on GABAA Receptor-Mediated Ion Currents. J Ginseng Res. 2012 Jan;36(1):55-60. PMID: 23717104

Han B, Meng Q, Li Q, et al. Effect of 20(S)-protopanaxatriol and its epimeric derivatives on myocardial injury induced by isoproterenol. Arzneimittelforschung. 2011;61(3):148-52. PMID: 21528638.

" None Not dangerous goods.

LKT P6957 Protopanaxadiol 5 mg 169.9 Triterpene sapogenin found in species of Panax; GABA-A antagonist. 7755-01-3 ≥98% 460.73 C30H52O3 CC(=CCCC(C)(C1CCC2(C1C(CC3C2(CCC4C3(CCC(C4(C)C)O)C)C)O)C)O)C Ambient 4°C "Deb S, Chin MY, Adomat H, et al. Ginsenoside-mediated blockade of 1α,25-dihydroxyvitamin D3 inactivation in human liver and intestine in vitro. J Steroid Biochem Mol Biol. 2014 May;141:94-103. PMID: 24486455.

Xu H, Yu X, Qu S, et al. Protective effect of Panax quinquefolium 20(S)-protopanaxadiol saponins, isolated from Pana quinquefolium, on permanent focal cerebral ischemic injury in rats. Exp Ther Med. 2014 Jan;7(1):165-170. PMID: 24348784.

Zheng Y, Nan H, Hao M, et al. Antiproliferative effects of protopanaxadiol ginsenosides on human colorectal cancer cells. Biomed Rep. 2013 Jul;1(4):555-558. PMID: 24648985.

Zhang YL, Zhang R, Xu HL, et al. 20(S)-protopanaxadiol triggers mitochondrial-mediated apoptosis in human lung adenocarcinoma A549 cells via inhibiting the PI3K/Akt signaling pathway. Am J Chin Med. 2013;41(5):1137-52. PMID: 24117074.

Lee BH, Choi SH, Shin TJ, et al. Effects of Ginsenoside Metabolites on GABAA Receptor-Mediated Ion Currents. J Ginseng Res. 2012 Jan;36(1):55-60. PMID: 23717104.

" None Not dangerous goods.

LKT P6957 Protopanaxadiol 10 mg 285.4 Triterpene sapogenin found in species of Panax; GABA-A antagonist. 7755-01-3 ≥98% 460.73 C30H52O3 CC(=CCCC(C)(C1CCC2(C1C(CC3C2(CCC4C3(CCC(C4(C)C)O)C)C)O)C)O)C Ambient 4°C "Deb S, Chin MY, Adomat H, et al. Ginsenoside-mediated blockade of 1α,25-dihydroxyvitamin D3 inactivation in human liver and intestine in vitro. J Steroid Biochem Mol Biol. 2014 May;141:94-103. PMID: 24486455.

Xu H, Yu X, Qu S, et al. Protective effect of Panax quinquefolium 20(S)-protopanaxadiol saponins, isolated from Pana quinquefolium, on permanent focal cerebral ischemic injury in rats. Exp Ther Med. 2014 Jan;7(1):165-170. PMID: 24348784.

Zheng Y, Nan H, Hao M, et al. Antiproliferative effects of protopanaxadiol ginsenosides on human colorectal cancer cells. Biomed Rep. 2013 Jul;1(4):555-558. PMID: 24648985.

Zhang YL, Zhang R, Xu HL, et al. 20(S)-protopanaxadiol triggers mitochondrial-mediated apoptosis in human lung adenocarcinoma A549 cells via inhibiting the PI3K/Akt signaling pathway. Am J Chin Med. 2013;41(5):1137-52. PMID: 24117074.

Lee BH, Choi SH, Shin TJ, et al. Effects of Ginsenoside Metabolites on GABAA Receptor-Mediated Ion Currents. J Ginseng Res. 2012 Jan;36(1):55-60. PMID: 23717104.

" None Not dangerous goods.

LKT P6957 Protopanaxadiol 25 mg 557.1 Triterpene sapogenin found in species of Panax; GABA-A antagonist. 7755-01-3 ≥98% 460.73 C30H52O3 CC(=CCCC(C)(C1CCC2(C1C(CC3C2(CCC4C3(CCC(C4(C)C)O)C)C)O)C)O)C Ambient 4°C "Deb S, Chin MY, Adomat H, et al. Ginsenoside-mediated blockade of 1α,25-dihydroxyvitamin D3 inactivation in human liver and intestine in vitro. J Steroid Biochem Mol Biol. 2014 May;141:94-103. PMID: 24486455.

Xu H, Yu X, Qu S, et al. Protective effect of Panax quinquefolium 20(S)-protopanaxadiol saponins, isolated from Pana quinquefolium, on permanent focal cerebral ischemic injury in rats. Exp Ther Med. 2014 Jan;7(1):165-170. PMID: 24348784.

Zheng Y, Nan H, Hao M, et al. Antiproliferative effects of protopanaxadiol ginsenosides on human colorectal cancer cells. Biomed Rep. 2013 Jul;1(4):555-558. PMID: 24648985.

Zhang YL, Zhang R, Xu HL, et al. 20(S)-protopanaxadiol triggers mitochondrial-mediated apoptosis in human lung adenocarcinoma A549 cells via inhibiting the PI3K/Akt signaling pathway. Am J Chin Med. 2013;41(5):1137-52. PMID: 24117074.

Lee BH, Choi SH, Shin TJ, et al. Effects of Ginsenoside Metabolites on GABAA Receptor-Mediated Ion Currents. J Ginseng Res. 2012 Jan;36(1):55-60. PMID: 23717104.

" None Not dangerous goods.

LKT P6956 Prostaglandin E1 1 mg 40.7 Endogenous prostaglandin, vasodilator. (11a,13E,15S)-11,15-Dihydroxy-9-oxoprost-13-enoic acid Alprostadil; PGE1; Caverject; Muse; Prostandin; Prostin VR 745-65-3 ≥98% 354.48 C20H34O5 CCCCCC(C=CC1C(CC(=O)C1CCCCCCC(=O)O)O)O Ambient -20°C Soluble in ethanol (5mg/mL) or acetone (10mg/mL). "Hanchanale V, Eardley I. Alprostadil for the treatment of impotence. Expert Opin Pharmacother. 2014 Feb;15(3):421-8. PMID: 24369066.

Brasileiro JL, Inoye CM, Aydos RD, et al. Ischemia and reperfusion of rat small intestine using pentoxyfilline and prostaglandin E1. Acta Cir Bras. 2013 Nov;28(11):767-73. PMID: 24316743.

Liu WJ, Zhang BC, Guo R, et al. Renoprotective effect of alprostadil in combination with statins in patients with mild to moderate renal failure undergoing coronary angiography. Chin Med J (Engl). 2013;126(18):3475-80. PMID: 24034093.

Inoue H, Aihara M, Tomioka M, et al. Specific enhancement of vascular endothelial growth factor (VEGF) production in ischemic region by alprostadil--potential therapeutic application in pharmaceutical regenerative medicine. J Pharmacol Sci. 2013;122(2):158-61. PMID: 23728380.

" Xn, Xi "UN number: 2811     Class: 6.1     Packing Group: III

Proper shipping name: Toxic solid, organic, n.o.s. (Prostaglandin E1)"

LKT P6956 Prostaglandin E1 5 mg 136 Endogenous prostaglandin, vasodilator. (11a,13E,15S)-11,15-Dihydroxy-9-oxoprost-13-enoic acid Alprostadil; PGE1; Caverject; Muse; Prostandin; Prostin VR 745-65-3 ≥98% 354.48 C20H34O5 CCCCCC(C=CC1C(CC(=O)C1CCCCCCC(=O)O)O)O Ambient -20°C Soluble in ethanol (5mg/mL) or acetone (10mg/mL). "Hanchanale V, Eardley I. Alprostadil for the treatment of impotence. Expert Opin Pharmacother. 2014 Feb;15(3):421-8. PMID: 24369066.

Brasileiro JL, Inoye CM, Aydos RD, et al. Ischemia and reperfusion of rat small intestine using pentoxyfilline and prostaglandin E1. Acta Cir Bras. 2013 Nov;28(11):767-73. PMID: 24316743.

Liu WJ, Zhang BC, Guo R, et al. Renoprotective effect of alprostadil in combination with statins in patients with mild to moderate renal failure undergoing coronary angiography. Chin Med J (Engl). 2013;126(18):3475-80. PMID: 24034093.

Inoue H, Aihara M, Tomioka M, et al. Specific enhancement of vascular endothelial growth factor (VEGF) production in ischemic region by alprostadil--potential therapeutic application in pharmaceutical regenerative medicine. J Pharmacol Sci. 2013;122(2):158-61. PMID: 23728380.

" Xn, Xi "UN number: 2811     Class: 6.1     Packing Group: III

Proper shipping name: Toxic solid, organic, n.o.s. (Prostaglandin E1)"

LKT P6956 Prostaglandin E1 10 mg 183.4 Endogenous prostaglandin, vasodilator. (11a,13E,15S)-11,15-Dihydroxy-9-oxoprost-13-enoic acid Alprostadil; PGE1; Caverject; Muse; Prostandin; Prostin VR 745-65-3 ≥98% 354.48 C20H34O5 CCCCCC(C=CC1C(CC(=O)C1CCCCCCC(=O)O)O)O Ambient -20°C Soluble in ethanol (5mg/mL) or acetone (10mg/mL). "Hanchanale V, Eardley I. Alprostadil for the treatment of impotence. Expert Opin Pharmacother. 2014 Feb;15(3):421-8. PMID: 24369066.

Brasileiro JL, Inoye CM, Aydos RD, et al. Ischemia and reperfusion of rat small intestine using pentoxyfilline and prostaglandin E1. Acta Cir Bras. 2013 Nov;28(11):767-73. PMID: 24316743.

Liu WJ, Zhang BC, Guo R, et al. Renoprotective effect of alprostadil in combination with statins in patients with mild to moderate renal failure undergoing coronary angiography. Chin Med J (Engl). 2013;126(18):3475-80. PMID: 24034093.

Inoue H, Aihara M, Tomioka M, et al. Specific enhancement of vascular endothelial growth factor (VEGF) production in ischemic region by alprostadil--potential therapeutic application in pharmaceutical regenerative medicine. J Pharmacol Sci. 2013;122(2):158-61. PMID: 23728380.

" Xn, Xi "UN number: 2811     Class: 6.1     Packing Group: III

Proper shipping name: Toxic solid, organic, n.o.s. (Prostaglandin E1)"

LKT P6901 Pramipexole Dihydrochloride 10 mg 67.9 D2/3 agonist. (S)-2-amino-4,5,6,7-tetrahydro-6-(propylamino)benzothiazole dihydrochloride 191217-81-9 ≥98% 302.26 C10H17N3S 2HCl H2O CCCNC1CCC2=C(C1)SC(=N2)N.O.Cl.Cl Ambient Ambient "Chau KY, Cooper JM, Schapira AH. Pramipexole reduces phosphorylation of α-synuclein at serine-129. J Mol Neurosci. 2013 Oct;51(2):573-80. PMID: 23681749.

Kitagawa K, Kitamura Y, Miyazaki T, et al. Effects of pramipexole on the duration of immobility during the forced swim test in normal and ACTH-treated rats. Naunyn Schmiedebergs Arch Pharmacol. 2009 Jul;380(1):59-66. PMID: 19274453.

Iravani MM, Sadeghian M, Leung CC, et al. Continuous subcutaneous infusion of pramipexole protects against lipopolysaccharide-induced dopaminergic cell death without affecting the inflammatory response. Exp Neurol. 2008 Aug;212(2):522-31. PMID: 18571649.

Zarate CA Jr, Payne JL, Singh J, et al. Pramipexole for bipolar II depression: a placebo-controlled proof of concept study. Biol Psychiatry. 2004 Jul 1;56(1):54-60. PMID: 15219473.

Ling ZD, Robie HC, Tong CW, et al. Both the antioxidant and D3 agonist actions of pramipexole mediate its neuroprotective actions in mesencephalic cultures. J Pharmacol Exp Ther. 1999 Apr;289(1):202-10. PMID: 10087005.

Ono K, Takasaki J, Takahashi R, et al. Effects of antiparkinsonian agents on beta-amyloid and alpha-synuclein oligomer formation in vitro. J Neurosci Res. 2013 Oct;91(10):1371-1381. PMID: 23913715." None Not dangerous goods.

LKT P6901 Pramipexole Dihydrochloride 25 mg 108.8 D2/3 agonist. (S)-2-amino-4,5,6,7-tetrahydro-6-(propylamino)benzothiazole dihydrochloride 191217-81-9 ≥98% 302.26 C10H17N3S 2HCl H2O CCCNC1CCC2=C(C1)SC(=N2)N.O.Cl.Cl Ambient Ambient "Chau KY, Cooper JM, Schapira AH. Pramipexole reduces phosphorylation of α-synuclein at serine-129. J Mol Neurosci. 2013 Oct;51(2):573-80. PMID: 23681749.

Kitagawa K, Kitamura Y, Miyazaki T, et al. Effects of pramipexole on the duration of immobility during the forced swim test in normal and ACTH-treated rats. Naunyn Schmiedebergs Arch Pharmacol. 2009 Jul;380(1):59-66. PMID: 19274453.

Iravani MM, Sadeghian M, Leung CC, et al. Continuous subcutaneous infusion of pramipexole protects against lipopolysaccharide-induced dopaminergic cell death without affecting the inflammatory response. Exp Neurol. 2008 Aug;212(2):522-31. PMID: 18571649.

Zarate CA Jr, Payne JL, Singh J, et al. Pramipexole for bipolar II depression: a placebo-controlled proof of concept study. Biol Psychiatry. 2004 Jul 1;56(1):54-60. PMID: 15219473.

Ling ZD, Robie HC, Tong CW, et al. Both the antioxidant and D3 agonist actions of pramipexole mediate its neuroprotective actions in mesencephalic cultures. J Pharmacol Exp Ther. 1999 Apr;289(1):202-10. PMID: 10087005.

Ono K, Takasaki J, Takahashi R, et al. Effects of antiparkinsonian agents on beta-amyloid and alpha-synuclein oligomer formation in vitro. J Neurosci Res. 2013 Oct;91(10):1371-1381. PMID: 23913715." None Not dangerous goods.

LKT P6901 Pramipexole Dihydrochloride 100 mg 285.4 D2/3 agonist. (S)-2-amino-4,5,6,7-tetrahydro-6-(propylamino)benzothiazole dihydrochloride 191217-81-9 ≥98% 302.26 C10H17N3S 2HCl H2O CCCNC1CCC2=C(C1)SC(=N2)N.O.Cl.Cl Ambient Ambient "Chau KY, Cooper JM, Schapira AH. Pramipexole reduces phosphorylation of α-synuclein at serine-129. J Mol Neurosci. 2013 Oct;51(2):573-80. PMID: 23681749.

Kitagawa K, Kitamura Y, Miyazaki T, et al. Effects of pramipexole on the duration of immobility during the forced swim test in normal and ACTH-treated rats. Naunyn Schmiedebergs Arch Pharmacol. 2009 Jul;380(1):59-66. PMID: 19274453.

Iravani MM, Sadeghian M, Leung CC, et al. Continuous subcutaneous infusion of pramipexole protects against lipopolysaccharide-induced dopaminergic cell death without affecting the inflammatory response. Exp Neurol. 2008 Aug;212(2):522-31. PMID: 18571649.

Zarate CA Jr, Payne JL, Singh J, et al. Pramipexole for bipolar II depression: a placebo-controlled proof of concept study. Biol Psychiatry. 2004 Jul 1;56(1):54-60. PMID: 15219473.

Ling ZD, Robie HC, Tong CW, et al. Both the antioxidant and D3 agonist actions of pramipexole mediate its neuroprotective actions in mesencephalic cultures. J Pharmacol Exp Ther. 1999 Apr;289(1):202-10. PMID: 10087005.

Ono K, Takasaki J, Takahashi R, et al. Effects of antiparkinsonian agents on beta-amyloid and alpha-synuclein oligomer formation in vitro. J Neurosci Res. 2013 Oct;91(10):1371-1381. PMID: 23913715." None Not dangerous goods.

LKT P6859 Proctolin 1 mg 60 Neuropeptide found in crustaceans and insects. 57966-42-4 ≥95% 648.77 C30H48N8O8 CC(C)CC(C(=O)N1CCCC1C(=O)NC(C(C)O)C(=O)O)NC(=O)C(CC2=CC=C(C=C2)O)NC(=O)C(CCCN=C(N)N)N Ambient -20°C "Wilkens J. Possible mechanisms of control of vascular resistance in the lobster Homarus americanus J Exp Biol. 1997;200(Pt 3):487-93. PMID: 9318157.

Hertel W, Richter M, Rapus J, et al. The role of proctolin in the antenna-heart beat acceleration of Periplaneta americana (L.). Acta Biol Hung. 1995;46(2-4):491-506. PMID: 8853723.

Goudey-Perrière F, Perrière C, Brousse-Gaury P. Proctolin promotes vitellogenesis onset in the imaginal molt decapitated cockroach Blaberus craniifer. Comp Biochem Physiol Comp Physiol. 1994 Aug;108(4):533-42. PMID: 7915658.

Pasztor VM, Lange AB, Orchard I. Stretch-induced release of proctolin from the dendrites of a lobster sense organ. Brain Res. 1988 Aug 16;458(1):199-203. PMID: 2905194.

" Not dangerous goods.

LKT P6859 Proctolin 2 mg 101.9 Neuropeptide found in crustaceans and insects. 57966-42-4 ≥95% 648.77 C30H48N8O8 CC(C)CC(C(=O)N1CCCC1C(=O)NC(C(C)O)C(=O)O)NC(=O)C(CC2=CC=C(C=C2)O)NC(=O)C(CCCN=C(N)N)N Ambient -20°C "Wilkens J. Possible mechanisms of control of vascular resistance in the lobster Homarus americanus J Exp Biol. 1997;200(Pt 3):487-93. PMID: 9318157.

Hertel W, Richter M, Rapus J, et al. The role of proctolin in the antenna-heart beat acceleration of Periplaneta americana (L.). Acta Biol Hung. 1995;46(2-4):491-506. PMID: 8853723.

Goudey-Perrière F, Perrière C, Brousse-Gaury P. Proctolin promotes vitellogenesis onset in the imaginal molt decapitated cockroach Blaberus craniifer. Comp Biochem Physiol Comp Physiol. 1994 Aug;108(4):533-42. PMID: 7915658.

Pasztor VM, Lange AB, Orchard I. Stretch-induced release of proctolin from the dendrites of a lobster sense organ. Brain Res. 1988 Aug 16;458(1):199-203. PMID: 2905194.

" Not dangerous goods.

LKT P6859 Proctolin 5 mg 180 Neuropeptide found in crustaceans and insects. 57966-42-4 ≥95% 648.77 C30H48N8O8 CC(C)CC(C(=O)N1CCCC1C(=O)NC(C(C)O)C(=O)O)NC(=O)C(CC2=CC=C(C=C2)O)NC(=O)C(CCCN=C(N)N)N Ambient -20°C "Wilkens J. Possible mechanisms of control of vascular resistance in the lobster Homarus americanus J Exp Biol. 1997;200(Pt 3):487-93. PMID: 9318157.

Hertel W, Richter M, Rapus J, et al. The role of proctolin in the antenna-heart beat acceleration of Periplaneta americana (L.). Acta Biol Hung. 1995;46(2-4):491-506. PMID: 8853723.

Goudey-Perrière F, Perrière C, Brousse-Gaury P. Proctolin promotes vitellogenesis onset in the imaginal molt decapitated cockroach Blaberus craniifer. Comp Biochem Physiol Comp Physiol. 1994 Aug;108(4):533-42. PMID: 7915658.

Pasztor VM, Lange AB, Orchard I. Stretch-induced release of proctolin from the dendrites of a lobster sense organ. Brain Res. 1988 Aug 16;458(1):199-203. PMID: 2905194.

" Not dangerous goods.

LKT P6857 Protocatechuic Acid 25 g 74.3 Polyphenol found in many plants and foods. 4-Carboxy-1,2-dihydroxybenzene 3,4-Dihydroxybenzoic acid 99-50-3 ≥97% 154.12 C7H6O4 C1=CC(=C(C=C1C(=O)O)O)O Ambient Ambient Slightly soluble in water. Soluble in alcohol or ether. "Kuriyama I, Nakajima Y, Nishida H, et al. Inhibitory effects of low molecular weight polyphenolics from Inonotus obliquus on human DNA topoisomerase activity and cancer cell proliferation. Mol Med Rep. 2013 Aug;8(2):535-42. PMID: 23799608.

Ou CB, Pan Q, Chen X, et al. Protocatechuic acid, a new active substance against the challenge of avian infectious bursal disease virus. Poult Sci. 2012 Jul;91(7):1604-9. Erratum in: Poult Sci. 2012 Oct;91(10):2722. Pang, Q [corrected to Pan, Q].  PMID: 22700505.

Lin HH, Chen JH, Chou FP, et al. Protocatechuic acid inhibits cancer cell metastasis involving the down-regulation of Ras/Akt/NF-κB pathway and MMP-2 production by targeting RhoB activation. Br J Pharmacol. 2011 Jan;162(1):237-54. PMID: 20840540.

Cao YG, Zhang L, Ma C, et al. Metabolism of protocatechuic acid influences fatty acid oxidation in rat heart: new anti-angina mechanism implication. Biochem Pharmacol. 2009 Mar 15;77(6):1096-104. PMID: 19109930.

Liu YM, Jiang B, Bao YM, et al. Protocatechuic acid inhibits apoptosis by mitochondrial dysfunction in rotenone-induced PC12 cells. Toxicol In Vitro. 2008 Mar;22(2):430-7. PMID: 18082360.

Lin HH, Chen JH, Huang CC, et al. Apoptotic effect of 3,4-dihydroxybenzoic acid on human gastric carcinoma cells involving JNK/p38 MAPK signaling activation. Int J Cancer. 2007 Jun 1;120(11):2306-16. PMID: 17304508.

" Xi Not dangerous goods.

LKT P6857 Protocatechuic Acid 50 g 134.9 Polyphenol found in many plants and foods. 4-Carboxy-1,2-dihydroxybenzene 3,4-Dihydroxybenzoic acid 99-50-3 ≥97% 154.12 C7H6O4 C1=CC(=C(C=C1C(=O)O)O)O Ambient Ambient Slightly soluble in water. Soluble in alcohol or ether. "Kuriyama I, Nakajima Y, Nishida H, et al. Inhibitory effects of low molecular weight polyphenolics from Inonotus obliquus on human DNA topoisomerase activity and cancer cell proliferation. Mol Med Rep. 2013 Aug;8(2):535-42. PMID: 23799608.

Ou CB, Pan Q, Chen X, et al. Protocatechuic acid, a new active substance against the challenge of avian infectious bursal disease virus. Poult Sci. 2012 Jul;91(7):1604-9. Erratum in: Poult Sci. 2012 Oct;91(10):2722. Pang, Q [corrected to Pan, Q].  PMID: 22700505.

Lin HH, Chen JH, Chou FP, et al. Protocatechuic acid inhibits cancer cell metastasis involving the down-regulation of Ras/Akt/NF-κB pathway and MMP-2 production by targeting RhoB activation. Br J Pharmacol. 2011 Jan;162(1):237-54. PMID: 20840540.

Cao YG, Zhang L, Ma C, et al. Metabolism of protocatechuic acid influences fatty acid oxidation in rat heart: new anti-angina mechanism implication. Biochem Pharmacol. 2009 Mar 15;77(6):1096-104. PMID: 19109930.

Liu YM, Jiang B, Bao YM, et al. Protocatechuic acid inhibits apoptosis by mitochondrial dysfunction in rotenone-induced PC12 cells. Toxicol In Vitro. 2008 Mar;22(2):430-7. PMID: 18082360.

Lin HH, Chen JH, Huang CC, et al. Apoptotic effect of 3,4-dihydroxybenzoic acid on human gastric carcinoma cells involving JNK/p38 MAPK signaling activation. Int J Cancer. 2007 Jun 1;120(11):2306-16. PMID: 17304508.

" Xi Not dangerous goods.

LKT P6857 Protocatechuic Acid 100 g 215.8 Polyphenol found in many plants and foods. 4-Carboxy-1,2-dihydroxybenzene 3,4-Dihydroxybenzoic acid 99-50-3 ≥97% 154.12 C7H6O4 C1=CC(=C(C=C1C(=O)O)O)O Ambient Ambient Slightly soluble in water. Soluble in alcohol or ether. "Kuriyama I, Nakajima Y, Nishida H, et al. Inhibitory effects of low molecular weight polyphenolics from Inonotus obliquus on human DNA topoisomerase activity and cancer cell proliferation. Mol Med Rep. 2013 Aug;8(2):535-42. PMID: 23799608.

Ou CB, Pan Q, Chen X, et al. Protocatechuic acid, a new active substance against the challenge of avian infectious bursal disease virus. Poult Sci. 2012 Jul;91(7):1604-9. Erratum in: Poult Sci. 2012 Oct;91(10):2722. Pang, Q [corrected to Pan, Q].  PMID: 22700505.

Lin HH, Chen JH, Chou FP, et al. Protocatechuic acid inhibits cancer cell metastasis involving the down-regulation of Ras/Akt/NF-κB pathway and MMP-2 production by targeting RhoB activation. Br J Pharmacol. 2011 Jan;162(1):237-54. PMID: 20840540.

Cao YG, Zhang L, Ma C, et al. Metabolism of protocatechuic acid influences fatty acid oxidation in rat heart: new anti-angina mechanism implication. Biochem Pharmacol. 2009 Mar 15;77(6):1096-104. PMID: 19109930.

Liu YM, Jiang B, Bao YM, et al. Protocatechuic acid inhibits apoptosis by mitochondrial dysfunction in rotenone-induced PC12 cells. Toxicol In Vitro. 2008 Mar;22(2):430-7. PMID: 18082360.

Lin HH, Chen JH, Huang CC, et al. Apoptotic effect of 3,4-dihydroxybenzoic acid on human gastric carcinoma cells involving JNK/p38 MAPK signaling activation. Int J Cancer. 2007 Jun 1;120(11):2306-16. PMID: 17304508.

" Xi Not dangerous goods.

LKT P6855 (±)-S-Propyl-L-cysteine-S-oxide 10 mg 163.2 Organosulfur found in Allium; analog of alliin. ≥98% 179.24 C6H13NO3S Ambient -20°C "Yoshinari O, Shiojima Y, Igarashi K. Anti-obesity effects of onion extract in Zucker diabetic fatty rats. Nutrients. 2012 Oct 22;4(10):1518-26. PMID: 23201769.

Krest I, Glodek J, Keusgen M. Cysteine sulfoxides and alliinase activity of some Allium species. J Agric Food Chem. 2000 Aug;48(8):3753-60. PMID: 10956182.

" Not dangerous goods.

LKT P6855 (±)-S-Propyl-L-cysteine-S-oxide 25 mg 350.9 Organosulfur found in Allium; analog of alliin. ≥98% 179.24 C6H13NO3S Ambient -20°C "Yoshinari O, Shiojima Y, Igarashi K. Anti-obesity effects of onion extract in Zucker diabetic fatty rats. Nutrients. 2012 Oct 22;4(10):1518-26. PMID: 23201769.

Krest I, Glodek J, Keusgen M. Cysteine sulfoxides and alliinase activity of some Allium species. J Agric Food Chem. 2000 Aug;48(8):3753-60. PMID: 10956182.

" Not dangerous goods.

LKT P6854 Progesterone 5 g 30.3 Endogenous steroid hormone involved in reproduction;PR agonist, mineralocorticoid, nAChR, σ1/2 antagonist. Pregn-4-ene-3,20-dione Corlutin; Gesterol; Luteol; Prolutone; Prolidon; Syngesterone; Utrogestan 57-83-0 ≥98% 314.47 C21H30O2 CC(=O)C1CCC2C1(CCC3C2CCC4=CC(=O)CCC34C)C Ambient Ambient Insoluble in water. Soluble in alcohol, acetone or dioxane. "Johannessen M, Fontanilla D, Mavlyutov T, et al. Antagonist action of progesterone at σ-receptors in the modulation of voltage-gated sodium channels. Am J Physiol Cell Physiol. 2011 Feb;300(2):C328-37. Erratum in: Am J Physiol Cell Physiol. 2013 Nov 1;305(9):C997.  PMID: 21084640.

da Fonseca EB, Bittar RE, Carvalho MH, et al. Prophylactic administration of progesterone by vaginal suppository to reduce the incidence of spontaneous preterm birth in women at increased risk: a randomized placebo-controlled double-blind study. Am J Obstet Gynecol. 2003 Feb;188(2):419-24. PMID: 12592250.

Baulieu E, Schumacher M. Progesterone as a neuroactive neurosteroid, with special reference to the effect of progesterone on myelination. Steroids. 2000 Oct-Nov;65(10-11):605-12. PMID: 11108866.

Rupprecht R, Reul JM, van Steensel B, et al. Pharmacological and functional characterization of human mineralocorticoid and glucocorticoid receptor ligands. Eur J Pharmacol. 1993 Oct 15;247(2):145-54. PMID: 8282004.

" T, Xn, Carc. Not dangerous goods.

LKT P6854 Progesterone 25 g 88.3 Endogenous steroid hormone involved in reproduction;PR agonist, mineralocorticoid, nAChR, σ1/2 antagonist. Pregn-4-ene-3,20-dione Corlutin; Gesterol; Luteol; Prolutone; Prolidon; Syngesterone; Utrogestan 57-83-0 ≥98% 314.47 C21H30O2 CC(=O)C1CCC2C1(CCC3C2CCC4=CC(=O)CCC34C)C Ambient Ambient Insoluble in water. Soluble in alcohol, acetone or dioxane. "Johannessen M, Fontanilla D, Mavlyutov T, et al. Antagonist action of progesterone at σ-receptors in the modulation of voltage-gated sodium channels. Am J Physiol Cell Physiol. 2011 Feb;300(2):C328-37. Erratum in: Am J Physiol Cell Physiol. 2013 Nov 1;305(9):C997.  PMID: 21084640.

da Fonseca EB, Bittar RE, Carvalho MH, et al. Prophylactic administration of progesterone by vaginal suppository to reduce the incidence of spontaneous preterm birth in women at increased risk: a randomized placebo-controlled double-blind study. Am J Obstet Gynecol. 2003 Feb;188(2):419-24. PMID: 12592250.

Baulieu E, Schumacher M. Progesterone as a neuroactive neurosteroid, with special reference to the effect of progesterone on myelination. Steroids. 2000 Oct-Nov;65(10-11):605-12. PMID: 11108866.

Rupprecht R, Reul JM, van Steensel B, et al. Pharmacological and functional characterization of human mineralocorticoid and glucocorticoid receptor ligands. Eur J Pharmacol. 1993 Oct 15;247(2):145-54. PMID: 8282004.

" T, Xn, Carc. Not dangerous goods.

LKT P6854 Progesterone 100 g 407.7 Endogenous steroid hormone involved in reproduction;PR agonist, mineralocorticoid, nAChR, σ1/2 antagonist. Pregn-4-ene-3,20-dione Corlutin; Gesterol; Luteol; Prolutone; Prolidon; Syngesterone; Utrogestan 57-83-0 ≥98% 314.47 C21H30O2 CC(=O)C1CCC2C1(CCC3C2CCC4=CC(=O)CCC34C)C Ambient Ambient Insoluble in water. Soluble in alcohol, acetone or dioxane. "Johannessen M, Fontanilla D, Mavlyutov T, et al. Antagonist action of progesterone at σ-receptors in the modulation of voltage-gated sodium channels. Am J Physiol Cell Physiol. 2011 Feb;300(2):C328-37. Erratum in: Am J Physiol Cell Physiol. 2013 Nov 1;305(9):C997.  PMID: 21084640.

da Fonseca EB, Bittar RE, Carvalho MH, et al. Prophylactic administration of progesterone by vaginal suppository to reduce the incidence of spontaneous preterm birth in women at increased risk: a randomized placebo-controlled double-blind study. Am J Obstet Gynecol. 2003 Feb;188(2):419-24. PMID: 12592250.

Baulieu E, Schumacher M. Progesterone as a neuroactive neurosteroid, with special reference to the effect of progesterone on myelination. Steroids. 2000 Oct-Nov;65(10-11):605-12. PMID: 11108866.

Rupprecht R, Reul JM, van Steensel B, et al. Pharmacological and functional characterization of human mineralocorticoid and glucocorticoid receptor ligands. Eur J Pharmacol. 1993 Oct 15;247(2):145-54. PMID: 8282004.

" T, Xn, Carc. Not dangerous goods.

LKT P6852 Propafenone Hydrochloride 1 g 41.3 β-adrenergic antagonist, Kv1.4 and K2P2 K+ channel blocker. "1-[2-[2-Hydroxy-3-(propylamino)propoxy]phenyl]-3-

phenyl-1propanone hydrochloride " Arythmol; Pronon; Rythmol; Rytmonorm 34183-22-7 ≥98% 377.91 C21H27NO3 HCl CCCNCC(COC1=CC=CC=C1C(=O)CCC2=CC=CC=C2)O.Cl Ambient Ambient Soluble in basic lower aliphatic alcohols, chloroform and hot water. Slightly soluble in cold water. Insoluble in ether. "Schmidt C, Wiedmann F, Schweizer PA, et al. Class I antiarrhythmic drugs inhibit human cardiac two-pore-domain K(+) (K2P2) channels. Eur J Pharmacol. 2013 Dec 5;721(1-3):237-48. PMID: 24070813.

Huh S, Jung E, Lee J, et al. Mechanisms of melanogenesis inhibition by propafenone. Arch Dermatol Res. 2010 Sep;302(7):561-5. PMID: 20549222.

Tian L, Jiang X, Rasmusson R, et al. Effect of propafenone on Kv1.4 inactivation. J Physiol Biochem. 2006 Dec;62(4):263-70. PMID: 17615952.

" Xn Not dangerous goods.

LKT P6852 Propafenone Hydrochloride 5 g 121.4 β-adrenergic antagonist, Kv1.4 and K2P2 K+ channel blocker. "1-[2-[2-Hydroxy-3-(propylamino)propoxy]phenyl]-3-

phenyl-1propanone hydrochloride " Arythmol; Pronon; Rythmol; Rytmonorm 34183-22-7 ≥98% 377.91 C21H27NO3 HCl CCCNCC(COC1=CC=CC=C1C(=O)CCC2=CC=CC=C2)O.Cl Ambient Ambient Soluble in basic lower aliphatic alcohols, chloroform and hot water. Slightly soluble in cold water. Insoluble in ether. "Schmidt C, Wiedmann F, Schweizer PA, et al. Class I antiarrhythmic drugs inhibit human cardiac two-pore-domain K(+) (K2P2) channels. Eur J Pharmacol. 2013 Dec 5;721(1-3):237-48. PMID: 24070813.

Huh S, Jung E, Lee J, et al. Mechanisms of melanogenesis inhibition by propafenone. Arch Dermatol Res. 2010 Sep;302(7):561-5. PMID: 20549222.

Tian L, Jiang X, Rasmusson R, et al. Effect of propafenone on Kv1.4 inactivation. J Physiol Biochem. 2006 Dec;62(4):263-70. PMID: 17615952.

" Xn Not dangerous goods.

LKT P6850 Prolactin-Releasing Peptide (1-31), human 1 mg 540 Endogenous peptide hormone, involved in hormone secretion; GPR10 agonist. PrRP-31 ≥98% 3664.2 C160H252N56O42S Ambient -20°C "Yamashita M, Takayanagi Y, Yoshida M, et al. Involvement of prolactin-releasing peptide in the activation of oxytocin neurones in response to food intake. J Neuroendocrinol. 2013 May;25(5):455-65. PMID: 23363338.

Romero A, Manríquez R, Alvarez C, et al. Prolactin-releasing peptide is a potent mediator of the innate immune response in leukocytes from Salmo salar. Vet Immunol Immunopathol. 2012 Jun 30;147(3-4):170-9. PMID: 22578983.

Seal LJ, Small CJ, Kim MS, et al. Prolactin releasing peptide (PrRP) stimulates luteinizing hormone (LH) and follicle stimulating hormone (FSH) via a hypothalamic mechanism in male rats. Endocrinology. 2000 May;141(5):1909-12. PMID: 10803604.

" Not dangerous goods.

LKT P6818 Prednisolone 1 g 32.8 Cortisol derivative; glucocorticoid agonist. (11β)-11,17,21-Trihydroxypregna-1,4-diene-3,20-dione Cortalone; Decaprednil; Decortin H; Deltasolone; Flamasone; Hydrodeltalone; Paracortol; Sterolone 50-24-8 ≥98% 360.44 C21H28O5 CC12CC(C3C(C1CCC2(C(=O)CO)O)CCC4=CC(=O)C=CC34C)O Ambient Ambient Slightly soluble in water (1 mM). Soluble in methanol and dioxane. Soluble in ethanol (33 mg/mL), DMSO (633 mM) "Frisullo G, Nociti V, Iorio R, et al. Glucocorticoid treatment reduces T-bet and pSTAT1 expression in mononuclear cells from relapsing remitting multiple sclerosis patients. Clin Immunol. 2007 Sep;124(3):284-93. PMID: 17627892.

Fisher I, Abraham D, Bouri K, et al. Prednisolone-induced changes in dystrophic skeletal muscle. FASEB J. 2005 May;19(7):834-6. Erratum in: FASEB J. 2005 May;19(7):1 p following 836. Hoffmann, Eric P [corrected to Hoffman, Eric P]. PMID: 15734791.

Davis M, Williams R, Chakraborty J, et al. Prednisone or prednisolone for the treatment of chronic active hepatitis? A comparison of plasma availability. Br J Clin Pharmacol. 1978 Jun;5(6):501-5. PMID: 656293.

" Xn, F, C Not dangerous goods.

LKT P6818 Prednisolone 5 g 115.3 Cortisol derivative; glucocorticoid agonist. (11β)-11,17,21-Trihydroxypregna-1,4-diene-3,20-dione Cortalone; Decaprednil; Decortin H; Deltasolone; Flamasone; Hydrodeltalone; Paracortol; Sterolone 50-24-8 ≥98% 360.44 C21H28O5 CC12CC(C3C(C1CCC2(C(=O)CO)O)CCC4=CC(=O)C=CC34C)O Ambient Ambient Slightly soluble in water (1 mM). Soluble in methanol and dioxane. Soluble in ethanol (33 mg/mL), DMSO (633 mM) "Frisullo G, Nociti V, Iorio R, et al. Glucocorticoid treatment reduces T-bet and pSTAT1 expression in mononuclear cells from relapsing remitting multiple sclerosis patients. Clin Immunol. 2007 Sep;124(3):284-93. PMID: 17627892.

Fisher I, Abraham D, Bouri K, et al. Prednisolone-induced changes in dystrophic skeletal muscle. FASEB J. 2005 May;19(7):834-6. Erratum in: FASEB J. 2005 May;19(7):1 p following 836. Hoffmann, Eric P [corrected to Hoffman, Eric P]. PMID: 15734791.

Davis M, Williams R, Chakraborty J, et al. Prednisone or prednisolone for the treatment of chronic active hepatitis? A comparison of plasma availability. Br J Clin Pharmacol. 1978 Jun;5(6):501-5. PMID: 656293.

" Xn, F, C Not dangerous goods.

LKT P6818 Prednisolone 10 g 218.4 Cortisol derivative; glucocorticoid agonist. (11β)-11,17,21-Trihydroxypregna-1,4-diene-3,20-dione Cortalone; Decaprednil; Decortin H; Deltasolone; Flamasone; Hydrodeltalone; Paracortol; Sterolone 50-24-8 ≥98% 360.44 C21H28O5 CC12CC(C3C(C1CCC2(C(=O)CO)O)CCC4=CC(=O)C=CC34C)O Ambient Ambient Slightly soluble in water (1 mM). Soluble in methanol and dioxane. Soluble in ethanol (33 mg/mL), DMSO (633 mM) "Frisullo G, Nociti V, Iorio R, et al. Glucocorticoid treatment reduces T-bet and pSTAT1 expression in mononuclear cells from relapsing remitting multiple sclerosis patients. Clin Immunol. 2007 Sep;124(3):284-93. PMID: 17627892.

Fisher I, Abraham D, Bouri K, et al. Prednisolone-induced changes in dystrophic skeletal muscle. FASEB J. 2005 May;19(7):834-6. Erratum in: FASEB J. 2005 May;19(7):1 p following 836. Hoffmann, Eric P [corrected to Hoffman, Eric P]. PMID: 15734791.

Davis M, Williams R, Chakraborty J, et al. Prednisone or prednisolone for the treatment of chronic active hepatitis? A comparison of plasma availability. Br J Clin Pharmacol. 1978 Jun;5(6):501-5. PMID: 656293.

" Xn, F, C Not dangerous goods.

LKT P6802 Pranoprofen 100 mg 67.9 NSAID; COX-1/2 inhibitor. α-Methyl-5H-[1]benzopyranol[2,3-b]pyridine-7-acetic acid Y-8004; Niflan 52549-17-4 ≥98% 255.27 C15H13NO3 CC(C1=CC2=C(C=C1)OC3=C(C2)C=CC=N3)C(=O)O Ambient Ambient "Chen J, Dong F, Chen W, et al. Clinical efficacy of 0.1% pranoprofen in treatment of dry eye patients: a multicenter, randomized, controlled clinical trial. Chin Med J (Engl). 2014 Jul;127(13):2407-12. PMID: 24985574.

Aratani H, Iwahisa Y, Imayoshi T, et al. Mechanism of the inhibitory effect of pranoprofen on sodium urate crystal-induced inflammation. Nihon Yakurigaku Zasshi. 1987 Mar;89(3):139-44.  PMID: 3556352.

" Not dangerous goods.

LKT P6802 Pranoprofen 250 mg 122.3 NSAID; COX-1/2 inhibitor. α-Methyl-5H-[1]benzopyranol[2,3-b]pyridine-7-acetic acid Y-8004; Niflan 52549-17-4 ≥98% 255.27 C15H13NO3 CC(C1=CC2=C(C=C1)OC3=C(C2)C=CC=N3)C(=O)O Ambient Ambient "Chen J, Dong F, Chen W, et al. Clinical efficacy of 0.1% pranoprofen in treatment of dry eye patients: a multicenter, randomized, controlled clinical trial. Chin Med J (Engl). 2014 Jul;127(13):2407-12. PMID: 24985574.

Aratani H, Iwahisa Y, Imayoshi T, et al. Mechanism of the inhibitory effect of pranoprofen on sodium urate crystal-induced inflammation. Nihon Yakurigaku Zasshi. 1987 Mar;89(3):139-44.  PMID: 3556352.

" Not dangerous goods.

LKT P6802 Pranoprofen 1 g 305.9 NSAID; COX-1/2 inhibitor. α-Methyl-5H-[1]benzopyranol[2,3-b]pyridine-7-acetic acid Y-8004; Niflan 52549-17-4 ≥98% 255.27 C15H13NO3 CC(C1=CC2=C(C=C1)OC3=C(C2)C=CC=N3)C(=O)O Ambient Ambient "Chen J, Dong F, Chen W, et al. Clinical efficacy of 0.1% pranoprofen in treatment of dry eye patients: a multicenter, randomized, controlled clinical trial. Chin Med J (Engl). 2014 Jul;127(13):2407-12. PMID: 24985574.

Aratani H, Iwahisa Y, Imayoshi T, et al. Mechanism of the inhibitory effect of pranoprofen on sodium urate crystal-induced inflammation. Nihon Yakurigaku Zasshi. 1987 Mar;89(3):139-44.  PMID: 3556352.

" Not dangerous goods.

LKT P6801 Pravastatin Sodium 10 mg 33.9 Statin; HMG-CoA reductase inhibitor. (βR,δR,1S,2S,6S,8S,8aR)-1,2,6,7,8,8a-Hexahydro-β,δ,6-trihydroxy-2-methyl-8-[(2S)-2-methyl-1-oxobutoxy]-1-naphthaleneheptanoic acid monosodium salt Pravachol; Lipostat; Mevalotin; Liprevil; Pravaselect 81131-70-6 ≥98% 446.51 C23H35NaO7 CCC(C)C(=O)OC1CC(C=C2C1C(C(C=C2)C)CCC(CC(CC(=O)[O-])O)O)O.[Na+] Ambient 4°C Soluble in methanol, water (>400 mg/mL), DMSO, chloroform or ether. "Lee SJ, Lee I, Lee J, et al. Statins, 3-hydroxy-3-methylglutaryl coenzyme A reductase inhibitors, potentiate the anti-angiogenic effects of bevacizumab by suppressing angiopoietin2, BiP, and Hsp90α in human colorectal cancer. Br J Cancer. 2014 Jun 19. [Epub ahead of print]. PMID: 24945998.

Wu G, Xie Q, Xu L, et al. Pravastatin inhibits plaque rupture and subsequent thrombus formation in atherosclerotic rabbits with hyperlipidemia. Chem Pharm Bull (Tokyo). 2013;61(2):121-4. PMID: 23207681.

Luzak B, Rywaniak J, Stanczyk L, et al. Pravastatin and simvastatin improves acetylsalicylic acid-mediated in vitro blood platelet inhibition. Eur J Clin Invest. 2012 Aug;42(8):864-72. PMID: 22409214.

Kassan M, Montero MJ, Sevilla MA. In vitro antioxidant activity of pravastatin provides vascular protection. Eur J Pharmacol. 2010 Mar 25;630(1-3):107-11. PMID: 20044990.

Imamura M, Okunishi K, Ohtsu H, et al. Pravastatin attenuates allergic airway inflammation by suppressing antigen sensitisation, interleukin 17 production and antigen presentation in the lung. Thorax. 2009 Jan;64(1):44-9. PMID: 18835962.

Kelesidis T, Currier JS, Huynh D, et al. A biochemical fluorometric method for asessing the oxidative properties of HDL. 2011 Dec;52(12):2341-2351. PMID: 21957198.

" None Not dangerous goods.

LKT P6801 Pravastatin Sodium 50 mg 101.9 Statin; HMG-CoA reductase inhibitor. (βR,δR,1S,2S,6S,8S,8aR)-1,2,6,7,8,8a-Hexahydro-β,δ,6-trihydroxy-2-methyl-8-[(2S)-2-methyl-1-oxobutoxy]-1-naphthaleneheptanoic acid monosodium salt Pravachol; Lipostat; Mevalotin; Liprevil; Pravaselect 81131-70-6 ≥98% 446.51 C23H35NaO7 CCC(C)C(=O)OC1CC(C=C2C1C(C(C=C2)C)CCC(CC(CC(=O)[O-])O)O)O.[Na+] Ambient 4°C Soluble in methanol, water (>400 mg/mL), DMSO, chloroform or ether. "Lee SJ, Lee I, Lee J, et al. Statins, 3-hydroxy-3-methylglutaryl coenzyme A reductase inhibitors, potentiate the anti-angiogenic effects of bevacizumab by suppressing angiopoietin2, BiP, and Hsp90α in human colorectal cancer. Br J Cancer. 2014 Jun 19. [Epub ahead of print]. PMID: 24945998.

Wu G, Xie Q, Xu L, et al. Pravastatin inhibits plaque rupture and subsequent thrombus formation in atherosclerotic rabbits with hyperlipidemia. Chem Pharm Bull (Tokyo). 2013;61(2):121-4. PMID: 23207681.

Luzak B, Rywaniak J, Stanczyk L, et al. Pravastatin and simvastatin improves acetylsalicylic acid-mediated in vitro blood platelet inhibition. Eur J Clin Invest. 2012 Aug;42(8):864-72. PMID: 22409214.

Kassan M, Montero MJ, Sevilla MA. In vitro antioxidant activity of pravastatin provides vascular protection. Eur J Pharmacol. 2010 Mar 25;630(1-3):107-11. PMID: 20044990.

Imamura M, Okunishi K, Ohtsu H, et al. Pravastatin attenuates allergic airway inflammation by suppressing antigen sensitisation, interleukin 17 production and antigen presentation in the lung. Thorax. 2009 Jan;64(1):44-9. PMID: 18835962.

Kelesidis T, Currier JS, Huynh D, et al. A biochemical fluorometric method for asessing the oxidative properties of HDL. 2011 Dec;52(12):2341-2351. PMID: 21957198.

" None Not dangerous goods.

LKT P6801 Pravastatin Sodium 100 mg 169.9 Statin; HMG-CoA reductase inhibitor. (βR,δR,1S,2S,6S,8S,8aR)-1,2,6,7,8,8a-Hexahydro-β,δ,6-trihydroxy-2-methyl-8-[(2S)-2-methyl-1-oxobutoxy]-1-naphthaleneheptanoic acid monosodium salt Pravachol; Lipostat; Mevalotin; Liprevil; Pravaselect 81131-70-6 ≥98% 446.51 C23H35NaO7 CCC(C)C(=O)OC1CC(C=C2C1C(C(C=C2)C)CCC(CC(CC(=O)[O-])O)O)O.[Na+] Ambient 4°C Soluble in methanol, water (>400 mg/mL), DMSO, chloroform or ether. "Lee SJ, Lee I, Lee J, et al. Statins, 3-hydroxy-3-methylglutaryl coenzyme A reductase inhibitors, potentiate the anti-angiogenic effects of bevacizumab by suppressing angiopoietin2, BiP, and Hsp90α in human colorectal cancer. Br J Cancer. 2014 Jun 19. [Epub ahead of print]. PMID: 24945998.

Wu G, Xie Q, Xu L, et al. Pravastatin inhibits plaque rupture and subsequent thrombus formation in atherosclerotic rabbits with hyperlipidemia. Chem Pharm Bull (Tokyo). 2013;61(2):121-4. PMID: 23207681.

Luzak B, Rywaniak J, Stanczyk L, et al. Pravastatin and simvastatin improves acetylsalicylic acid-mediated in vitro blood platelet inhibition. Eur J Clin Invest. 2012 Aug;42(8):864-72. PMID: 22409214.

Kassan M, Montero MJ, Sevilla MA. In vitro antioxidant activity of pravastatin provides vascular protection. Eur J Pharmacol. 2010 Mar 25;630(1-3):107-11. PMID: 20044990.

Imamura M, Okunishi K, Ohtsu H, et al. Pravastatin attenuates allergic airway inflammation by suppressing antigen sensitisation, interleukin 17 production and antigen presentation in the lung. Thorax. 2009 Jan;64(1):44-9. PMID: 18835962.

Kelesidis T, Currier JS, Huynh D, et al. A biochemical fluorometric method for asessing the oxidative properties of HDL. 2011 Dec;52(12):2341-2351. PMID: 21957198.

" None Not dangerous goods.

LKT P1765 Peptide Standard 1 0.5 mg 144 ≥95% 2152.52 C98H144N25O26S2 Ambient -20°C "

"

LKT P1765 Peptide Standard 1 1 mg 245.9 ≥95% 2152.52 C98H144N25O26S2 Ambient -20°C "

"

LKT P1765 Peptide Standard 1 2.5 mg 432 ≥95% 2152.52 C98H144N25O26S2 Ambient -20°C "

"

LKT P1766 Peptide B, cow 0.5 mg 192.3 Peptide, fibrinogen-derivative. ≥95% 2153.49 C163H239N39O53S2 Ambient -20°C "Nichols WW, Mehta J, Wargovich T, et al. Fibrin(ogen)-derived peptide B beta 30-43 increases coronary blood flow in the anesthetized dog. Thromb Res. 1985 Jul 15;39(2):223-9. PMID: 3895564.

Osbahr AJ, Custodio R. Action of peptide-B from bovine fibrinogen on ATPase activity and superprecipitation of myosin B. Am J Physiol. 1975 Feb;228(2):488-95. PMID: 123418.

Osbahr AJ. The hemostatic effect of bovine peptide-B from fibrinogen. Thromb Diath Haemorrh. 1974 Sep 30;32(1):149-56. PMID: 4454037.

" Not dangerous goods.

LKT P1766 Peptide B, cow 1 mg 327.1 Peptide, fibrinogen-derivative. ≥95% 2153.49 C163H239N39O53S2 Ambient -20°C "Nichols WW, Mehta J, Wargovich T, et al. Fibrin(ogen)-derived peptide B beta 30-43 increases coronary blood flow in the anesthetized dog. Thromb Res. 1985 Jul 15;39(2):223-9. PMID: 3895564.

Osbahr AJ, Custodio R. Action of peptide-B from bovine fibrinogen on ATPase activity and superprecipitation of myosin B. Am J Physiol. 1975 Feb;228(2):488-95. PMID: 123418.

Osbahr AJ. The hemostatic effect of bovine peptide-B from fibrinogen. Thromb Diath Haemorrh. 1974 Sep 30;32(1):149-56. PMID: 4454037.

" Not dangerous goods.

LKT P1766 Peptide B, cow 2.5 mg 576.1 Peptide, fibrinogen-derivative. ≥95% 2153.49 C163H239N39O53S2 Ambient -20°C "Nichols WW, Mehta J, Wargovich T, et al. Fibrin(ogen)-derived peptide B beta 30-43 increases coronary blood flow in the anesthetized dog. Thromb Res. 1985 Jul 15;39(2):223-9. PMID: 3895564.

Osbahr AJ, Custodio R. Action of peptide-B from bovine fibrinogen on ATPase activity and superprecipitation of myosin B. Am J Physiol. 1975 Feb;228(2):488-95. PMID: 123418.

Osbahr AJ. The hemostatic effect of bovine peptide-B from fibrinogen. Thromb Diath Haemorrh. 1974 Sep 30;32(1):149-56. PMID: 4454037.

" Not dangerous goods.

LKT P1767 Peptide F, cow 1 mg 396.1 Endogenous pro-enkephalin peptide. ≥95% 3657.08 C163H239N39O53S2 Ambient -20°C "Kraemer WJ, Mastro AM, Gordon SE, et al. Responses of plasma proenkephalin peptide F in rats following 14 days of spaceflight. Aviat Space Environ Med. 2004 Feb;75(2):114-7. PMID: 14960045.

Triplett-McBride NT, Mastro AM, McBride JM, et al. Plasma proenkephalin peptide F and human B cell responses to exercise stress in fit and unfit women. Peptides. 1998;19(4):731-8. PMID: 9622029.

"

LKT P1767 Peptide F, cow 2 mg 672.2 Endogenous pro-enkephalin peptide. ≥95% 3657.08 C163H239N39O53S2 Ambient -20°C "Kraemer WJ, Mastro AM, Gordon SE, et al. Responses of plasma proenkephalin peptide F in rats following 14 days of spaceflight. Aviat Space Environ Med. 2004 Feb;75(2):114-7. PMID: 14960045.

Triplett-McBride NT, Mastro AM, McBride JM, et al. Plasma proenkephalin peptide F and human B cell responses to exercise stress in fit and unfit women. Peptides. 1998;19(4):731-8. PMID: 9622029.

"

LKT P1767 Peptide F, cow 5 mg 1188.1 Endogenous pro-enkephalin peptide. ≥95% 3657.08 C163H239N39O53S2 Ambient -20°C "Kraemer WJ, Mastro AM, Gordon SE, et al. Responses of plasma proenkephalin peptide F in rats following 14 days of spaceflight. Aviat Space Environ Med. 2004 Feb;75(2):114-7. PMID: 14960045.

Triplett-McBride NT, Mastro AM, McBride JM, et al. Plasma proenkephalin peptide F and human B cell responses to exercise stress in fit and unfit women. Peptides. 1998;19(4):731-8. PMID: 9622029.

"

LKT P1768 Peptide YY (3-36), human 0.5 mg 300.1 Endogenous neuropeptide fragment, involved in enteric movement and feeding behavior; Y1/2 agonist. PYY 123583-37-9 ≥95% 4049.55 C180H279N53O54 CCC(C)C(C(=O)NC(CCCCN)C(=O)N1CCCC1C(=O)NC(CCC(=O)O)C(=O)NC(C)C(=O)N2CCCC2C(=O)NCC(=O)NC(CCC(=O)O)C(=O)NC(CC(=O)O)C(=O)NC(C)C(=O)NC(CO)C(=O)N3CCCC3C(=O)NC(CCC(=O)O)C(=O)NC(CCC(=O)O)C(=O)NC(CC(C)C)C(=O)NC(CC(=O)N)C(=O)NC(CCCNC(=N)N)C(=O)NC(CC4=CC=C(C=C4)O)C(=O)NC(CC5=CC=C(C=C5)O)C(=O)NC(C)C(=O)NC(CO)C(=O)NC(CC(C)C)C(=O)NC(CCCNC(=N)N)C(=O)NC(CC6=CNC=N6)C(=O)NC(CC7=CC=C(C=C7)O)C(=O)NC(CC(C)C)C(=O)NC(CC(=O)N)C(=O)NC(CC(C)C)C(=O)NC(C(C)C)C(=O)NC(C(C)O)C(=O)NC(CCCNC(=N)N)C(=O)NC(CCC(=O)N)C(=O)NC(CCCNC(=N)N)C(=O)NC(CC8=CC=C(C=C8)O)C(=O)N)N Ambient -20°C "Wong IP, Driessler F, Khor EC, et al. Peptide YY regulates bone remodeling in mice: a link between gut and skeletal biology. PLoS One. 2012;7(7):e40038. PMID: 22792209.

Shi YC, Hämmerle CM, Lee IC, et al. Adult-onset PYY overexpression in mice reduces food intake and increases lipogenic capacity. Neuropeptides. 2012 Aug;46(4):173-82. PMID: 22575886.

Tough IR, Forbes S, Tolhurst R, et al. Endogenous peptide YY and neuropeptide Y inhibit colonic ion transport, contractility and transit differentially via Y1 and Y2 receptors. Br J Pharmacol. 2011 Sep;164(2b):471-84. PMID: 21457230.

" Not dangerous goods.

LKT P1768 Peptide YY (3-36), human 1 mg 510 Endogenous neuropeptide fragment, involved in enteric movement and feeding behavior; Y1/2 agonist. PYY 123583-37-9 ≥95% 4049.55 C180H279N53O54 CCC(C)C(C(=O)NC(CCCCN)C(=O)N1CCCC1C(=O)NC(CCC(=O)O)C(=O)NC(C)C(=O)N2CCCC2C(=O)NCC(=O)NC(CCC(=O)O)C(=O)NC(CC(=O)O)C(=O)NC(C)C(=O)NC(CO)C(=O)N3CCCC3C(=O)NC(CCC(=O)O)C(=O)NC(CCC(=O)O)C(=O)NC(CC(C)C)C(=O)NC(CC(=O)N)C(=O)NC(CCCNC(=N)N)C(=O)NC(CC4=CC=C(C=C4)O)C(=O)NC(CC5=CC=C(C=C5)O)C(=O)NC(C)C(=O)NC(CO)C(=O)NC(CC(C)C)C(=O)NC(CCCNC(=N)N)C(=O)NC(CC6=CNC=N6)C(=O)NC(CC7=CC=C(C=C7)O)C(=O)NC(CC(C)C)C(=O)NC(CC(=O)N)C(=O)NC(CC(C)C)C(=O)NC(C(C)C)C(=O)NC(C(C)O)C(=O)NC(CCCNC(=N)N)C(=O)NC(CCC(=O)N)C(=O)NC(CCCNC(=N)N)C(=O)NC(CC8=CC=C(C=C8)O)C(=O)N)N Ambient -20°C "Wong IP, Driessler F, Khor EC, et al. Peptide YY regulates bone remodeling in mice: a link between gut and skeletal biology. PLoS One. 2012;7(7):e40038. PMID: 22792209.

Shi YC, Hämmerle CM, Lee IC, et al. Adult-onset PYY overexpression in mice reduces food intake and increases lipogenic capacity. Neuropeptides. 2012 Aug;46(4):173-82. PMID: 22575886.

Tough IR, Forbes S, Tolhurst R, et al. Endogenous peptide YY and neuropeptide Y inhibit colonic ion transport, contractility and transit differentially via Y1 and Y2 receptors. Br J Pharmacol. 2011 Sep;164(2b):471-84. PMID: 21457230.

" Not dangerous goods.

LKT P1768 Peptide YY (3-36), human 2.5 mg 900.1 Endogenous neuropeptide fragment, involved in enteric movement and feeding behavior; Y1/2 agonist. PYY 123583-37-9 ≥95% 4049.55 C180H279N53O54 CCC(C)C(C(=O)NC(CCCCN)C(=O)N1CCCC1C(=O)NC(CCC(=O)O)C(=O)NC(C)C(=O)N2CCCC2C(=O)NCC(=O)NC(CCC(=O)O)C(=O)NC(CC(=O)O)C(=O)NC(C)C(=O)NC(CO)C(=O)N3CCCC3C(=O)NC(CCC(=O)O)C(=O)NC(CCC(=O)O)C(=O)NC(CC(C)C)C(=O)NC(CC(=O)N)C(=O)NC(CCCNC(=N)N)C(=O)NC(CC4=CC=C(C=C4)O)C(=O)NC(CC5=CC=C(C=C5)O)C(=O)NC(C)C(=O)NC(CO)C(=O)NC(CC(C)C)C(=O)NC(CCCNC(=N)N)C(=O)NC(CC6=CNC=N6)C(=O)NC(CC7=CC=C(C=C7)O)C(=O)NC(CC(C)C)C(=O)NC(CC(=O)N)C(=O)NC(CC(C)C)C(=O)NC(C(C)C)C(=O)NC(C(C)O)C(=O)NC(CCCNC(=N)N)C(=O)NC(CCC(=O)N)C(=O)NC(CCCNC(=N)N)C(=O)NC(CC8=CC=C(C=C8)O)C(=O)N)N Ambient -20°C "Wong IP, Driessler F, Khor EC, et al. Peptide YY regulates bone remodeling in mice: a link between gut and skeletal biology. PLoS One. 2012;7(7):e40038. PMID: 22792209.

Shi YC, Hämmerle CM, Lee IC, et al. Adult-onset PYY overexpression in mice reduces food intake and increases lipogenic capacity. Neuropeptides. 2012 Aug;46(4):173-82. PMID: 22575886.

Tough IR, Forbes S, Tolhurst R, et al. Endogenous peptide YY and neuropeptide Y inhibit colonic ion transport, contractility and transit differentially via Y1 and Y2 receptors. Br J Pharmacol. 2011 Sep;164(2b):471-84. PMID: 21457230.

" Not dangerous goods.

LKT P1770 Perillyl Alcohol 10 g 83 Terpene found in various plant and fruit sources; farnesyl transferase, geranylgeranyl transferase, telomerase, Na+/K+ ATPase inhibitor. (S)-(-)-Perillyl alcohol L(-)-Perillyl alcohol; Isocarveol; Perilla alcohol 18457-55-1 ≥85% 152.23 C10H16O CC(=C)C1CCC(=CC1)CO Ambient 4°C Soluble in ethanol and acetone. Insoluble in water. "Tabassum R, Vaibhav K, Shrivastava P, et al. Perillyl alcohol improves functional and histological outcomes against ischemia-reperfusion injury by attenuation of oxidative stress and repression of COX-2, NOS-2 and NF-κB in middle cerebral artery occlusion rats. Eur J Pharmacol. 2014 Sep 18. [Epub ahead of print]. PMID: 25240714.

Imamura M, Sasaki O, Okunishi K, et al. Perillyl alcohol suppresses antigen-induced immune responses in the lung. Biochem Biophys Res Commun. 2014 Jan 3;443(1):266-71. PMID: 24309112.

DA Fonseca CO, Teixeira RM, Silva JC, et al. Long-term outcome in patients with recurrent malignant glioma treated with Perillyl alcohol inhalation. Anticancer Res. 2013 Dec;33(12):5625-31. PMID: 24324108.

Koyama M, Sowa Y, Hitomi T, et al. Perillyl alcohol causes G1 arrest through p15(INK4b) and p21(WAF1/Cip1) induction. Oncol Rep. 2013 Feb;29(2):779-84. PMID: 23233050.

Sundin T, Peffley DM, Gauthier D, et al. The isoprenoid perillyl alcohol inhibits telomerase activity in prostate cancer cells. Biochimie. 2012 Dec;94(12):2639-48. PMID: 22902867.

Garcia DG, Amorim LM, de Castro Faria MV, et al. The anticancer drug perillyl alcohol is a Na/K-ATPase inhibitor. Mol Cell Biochem. 2010 Dec;345(1-2):29-34. PMID: 20689980.

Stratton SP, Alberts DS, Einspahr JG, et al. A phase 2a study of topical perillyl alcohol cream for chemoprevention of skin cancer. Cancer Prev Res (Phila). 2010 Feb;3(2):160-9. PMID: 20103724.

" Xi Not dangerous goods.

LKT P1770 Perillyl Alcohol 50 g 240 Terpene found in various plant and fruit sources; farnesyl transferase, geranylgeranyl transferase, telomerase, Na+/K+ ATPase inhibitor. (S)-(-)-Perillyl alcohol L(-)-Perillyl alcohol; Isocarveol; Perilla alcohol 18457-55-1 ≥85% 152.23 C10H16O CC(=C)C1CCC(=CC1)CO Ambient 4°C Soluble in ethanol and acetone. Insoluble in water. "Tabassum R, Vaibhav K, Shrivastava P, et al. Perillyl alcohol improves functional and histological outcomes against ischemia-reperfusion injury by attenuation of oxidative stress and repression of COX-2, NOS-2 and NF-κB in middle cerebral artery occlusion rats. Eur J Pharmacol. 2014 Sep 18. [Epub ahead of print]. PMID: 25240714.

Imamura M, Sasaki O, Okunishi K, et al. Perillyl alcohol suppresses antigen-induced immune responses in the lung. Biochem Biophys Res Commun. 2014 Jan 3;443(1):266-71. PMID: 24309112.

DA Fonseca CO, Teixeira RM, Silva JC, et al. Long-term outcome in patients with recurrent malignant glioma treated with Perillyl alcohol inhalation. Anticancer Res. 2013 Dec;33(12):5625-31. PMID: 24324108.

Koyama M, Sowa Y, Hitomi T, et al. Perillyl alcohol causes G1 arrest through p15(INK4b) and p21(WAF1/Cip1) induction. Oncol Rep. 2013 Feb;29(2):779-84. PMID: 23233050.

Sundin T, Peffley DM, Gauthier D, et al. The isoprenoid perillyl alcohol inhibits telomerase activity in prostate cancer cells. Biochimie. 2012 Dec;94(12):2639-48. PMID: 22902867.

Garcia DG, Amorim LM, de Castro Faria MV, et al. The anticancer drug perillyl alcohol is a Na/K-ATPase inhibitor. Mol Cell Biochem. 2010 Dec;345(1-2):29-34. PMID: 20689980.

Stratton SP, Alberts DS, Einspahr JG, et al. A phase 2a study of topical perillyl alcohol cream for chemoprevention of skin cancer. Cancer Prev Res (Phila). 2010 Feb;3(2):160-9. PMID: 20103724.

" Xi Not dangerous goods.

LKT P1849 Pemetrexed Disodium 100 mg 75.3 Thymidylate synthase inhibitor, potential SHMT, DNFR, GARFT inhibitor. 150399-23-8 ≥98% 471.37 C20H19N5Na2O6 C1=CC(=CC=C1CCC2=CNC3=C2C(=O)N=C(N3)N)C(=O)NC(CCC(=O)[O-])C(=O)[O-].[Na+].[Na+] Ambient 4°C Water "Walters CL, Arend RC, Armstrong DK, et al. Folate and folate receptor alpha antagonists mechanism of action in ovarian cancer. Gynecol Oncol. 2013 Nov;131(2):493-8. PMID: 23863359.

Lau DH, Moon J, Davies AM, et al. Southwestern oncology group phase II trial (S0526) of pemetrexed in bronchioloalveolar carcinoma subtypes of advanced adenocarcinoma. Clin Lung Cancer. 2013 Jul;14(4):351-5. PMID: 23415808.

Yang TY, Chang GC, Chen KC, et al. Pemetrexed induces both intrinsic and extrinsic apoptosis through ataxia telangiectasia mutated/p53-dependent and -independent signaling pathways. Mol Carcinog. 2013 Mar;52(3):183-94. PMID: 22086658.

Su L, Liu G, Hao X, et al. Death receptor 5 and cellular FLICE-inhibitory protein regulate pemetrexed-induced apoptosis in human lung cancer cells. Eur J Cancer. 2011 Nov;47(16):2471-8. PMID: 21726997.

Daidone F, Florio R, Rinaldo S, et al. In silico and in vitro validation of serine hydroxymethyltransferase as a chemotherapeutic target of the antifolate drug pemetrexed. Eur J Med Chem. 2011 May;46(5):1616-21. PMID: 21371789.

Joerger M, Omlin A, Cerny T, et al. The role of pemetrexed in advanced non small-cell lung cancer: special focus on pharmacology and mechanism of action. Curr Drug Targets. 2010 Jan;11(1):37-47. PMID: 19839929.

Blackwood E, Epler J, Yen I, et al. Combination drug scheduling defines a “window of opportunity” for chemopotentiation of gemcitabine by an orally bioavailable, selective ChK1 inhibitor, GNE-900. Mol Cancer Ther. 2013 Oct;12(10):1968-1980. PMID: 23873850.

" Not dangerous goods.

LKT P1849 Pemetrexed Disodium 250 mg 137.1 Thymidylate synthase inhibitor, potential SHMT, DNFR, GARFT inhibitor. 150399-23-8 ≥98% 471.37 C20H19N5Na2O6 C1=CC(=CC=C1CCC2=CNC3=C2C(=O)N=C(N3)N)C(=O)NC(CCC(=O)[O-])C(=O)[O-].[Na+].[Na+] Ambient 4°C Water "Walters CL, Arend RC, Armstrong DK, et al. Folate and folate receptor alpha antagonists mechanism of action in ovarian cancer. Gynecol Oncol. 2013 Nov;131(2):493-8. PMID: 23863359.

Lau DH, Moon J, Davies AM, et al. Southwestern oncology group phase II trial (S0526) of pemetrexed in bronchioloalveolar carcinoma subtypes of advanced adenocarcinoma. Clin Lung Cancer. 2013 Jul;14(4):351-5. PMID: 23415808.

Yang TY, Chang GC, Chen KC, et al. Pemetrexed induces both intrinsic and extrinsic apoptosis through ataxia telangiectasia mutated/p53-dependent and -independent signaling pathways. Mol Carcinog. 2013 Mar;52(3):183-94. PMID: 22086658.

Su L, Liu G, Hao X, et al. Death receptor 5 and cellular FLICE-inhibitory protein regulate pemetrexed-induced apoptosis in human lung cancer cells. Eur J Cancer. 2011 Nov;47(16):2471-8. PMID: 21726997.

Daidone F, Florio R, Rinaldo S, et al. In silico and in vitro validation of serine hydroxymethyltransferase as a chemotherapeutic target of the antifolate drug pemetrexed. Eur J Med Chem. 2011 May;46(5):1616-21. PMID: 21371789.

Joerger M, Omlin A, Cerny T, et al. The role of pemetrexed in advanced non small-cell lung cancer: special focus on pharmacology and mechanism of action. Curr Drug Targets. 2010 Jan;11(1):37-47. PMID: 19839929.

Blackwood E, Epler J, Yen I, et al. Combination drug scheduling defines a “window of opportunity” for chemopotentiation of gemcitabine by an orally bioavailable, selective ChK1 inhibitor, GNE-900. Mol Cancer Ther. 2013 Oct;12(10):1968-1980. PMID: 23873850.

" Not dangerous goods.

LKT P1849 Pemetrexed Disodium 1 g 401.8 Thymidylate synthase inhibitor, potential SHMT, DNFR, GARFT inhibitor. 150399-23-8 ≥98% 471.37 C20H19N5Na2O6 C1=CC(=CC=C1CCC2=CNC3=C2C(=O)N=C(N3)N)C(=O)NC(CCC(=O)[O-])C(=O)[O-].[Na+].[Na+] Ambient 4°C Water "Walters CL, Arend RC, Armstrong DK, et al. Folate and folate receptor alpha antagonists mechanism of action in ovarian cancer. Gynecol Oncol. 2013 Nov;131(2):493-8. PMID: 23863359.

Lau DH, Moon J, Davies AM, et al. Southwestern oncology group phase II trial (S0526) of pemetrexed in bronchioloalveolar carcinoma subtypes of advanced adenocarcinoma. Clin Lung Cancer. 2013 Jul;14(4):351-5. PMID: 23415808.

Yang TY, Chang GC, Chen KC, et al. Pemetrexed induces both intrinsic and extrinsic apoptosis through ataxia telangiectasia mutated/p53-dependent and -independent signaling pathways. Mol Carcinog. 2013 Mar;52(3):183-94. PMID: 22086658.

Su L, Liu G, Hao X, et al. Death receptor 5 and cellular FLICE-inhibitory protein regulate pemetrexed-induced apoptosis in human lung cancer cells. Eur J Cancer. 2011 Nov;47(16):2471-8. PMID: 21726997.

Daidone F, Florio R, Rinaldo S, et al. In silico and in vitro validation of serine hydroxymethyltransferase as a chemotherapeutic target of the antifolate drug pemetrexed. Eur J Med Chem. 2011 May;46(5):1616-21. PMID: 21371789.

Joerger M, Omlin A, Cerny T, et al. The role of pemetrexed in advanced non small-cell lung cancer: special focus on pharmacology and mechanism of action. Curr Drug Targets. 2010 Jan;11(1):37-47. PMID: 19839929.

Blackwood E, Epler J, Yen I, et al. Combination drug scheduling defines a “window of opportunity” for chemopotentiation of gemcitabine by an orally bioavailable, selective ChK1 inhibitor, GNE-900. Mol Cancer Ther. 2013 Oct;12(10):1968-1980. PMID: 23873850.

" Not dangerous goods.

LKT P6800 Pravastatin Lactone 10 mg 89.3 Statin; HMG-CoA reductase inhibitor. (βR,δR,1S,2S,6S,8S,8aR)-1,2,6,7,8a-Hexahydro-β,δ,6-trihydroxy-2-methyl-8-[(2S)-2-methyl-1-oxobutoxy]-1-naphthaleneheptanoic acid lactone 85956-22-5 ≥92% 406.51 C23H34O6 CCC(C)C(=O)OC1CC(C=C2C1C(C(C=C2)C)CCC3CC(CC(=O)O3)O)O Ambient 4°C Soluble in water. "Lee SJ, Lee I, Lee J, et al. Statins, 3-hydroxy-3-methylglutaryl coenzyme A reductase inhibitors, potentiate the anti-angiogenic effects of bevacizumab by suppressing angiopoietin2, BiP, and Hsp90α in human colorectal cancer. Br J Cancer. 2014 Jun 19. [Epub ahead of print]. PMID: 24945998.

Wu G, Xie Q, Xu L, et al. Pravastatin inhibits plaque rupture and subsequent thrombus formation in atherosclerotic rabbits with hyperlipidemia. Chem Pharm Bull (Tokyo). 2013;61(2):121-4. PMID: 23207681.

Luzak B, Rywaniak J, Stanczyk L, et al. Pravastatin and simvastatin improves acetylsalicylic acid-mediated in vitro blood platelet inhibition. Eur J Clin Invest. 2012 Aug;42(8):864-72. PMID: 22409214.

Kassan M, Montero MJ, Sevilla MA. In vitro antioxidant activity of pravastatin provides vascular protection. Eur J Pharmacol. 2010 Mar 25;630(1-3):107-11. PMID: 20044990.

Imamura M, Okunishi K, Ohtsu H, et al. Pravastatin attenuates allergic airway inflammation by suppressing antigen sensitisation, interleukin 17 production and antigen presentation in the lung. Thorax. 2009 Jan;64(1):44-9. PMID: 18835962.

" Not dangerous goods.

LKT P6800 Pravastatin Lactone 50 mg 267 Statin; HMG-CoA reductase inhibitor. (βR,δR,1S,2S,6S,8S,8aR)-1,2,6,7,8a-Hexahydro-β,δ,6-trihydroxy-2-methyl-8-[(2S)-2-methyl-1-oxobutoxy]-1-naphthaleneheptanoic acid lactone 85956-22-5 ≥92% 406.51 C23H34O6 CCC(C)C(=O)OC1CC(C=C2C1C(C(C=C2)C)CCC3CC(CC(=O)O3)O)O Ambient 4°C Soluble in water. "Lee SJ, Lee I, Lee J, et al. Statins, 3-hydroxy-3-methylglutaryl coenzyme A reductase inhibitors, potentiate the anti-angiogenic effects of bevacizumab by suppressing angiopoietin2, BiP, and Hsp90α in human colorectal cancer. Br J Cancer. 2014 Jun 19. [Epub ahead of print]. PMID: 24945998.

Wu G, Xie Q, Xu L, et al. Pravastatin inhibits plaque rupture and subsequent thrombus formation in atherosclerotic rabbits with hyperlipidemia. Chem Pharm Bull (Tokyo). 2013;61(2):121-4. PMID: 23207681.

Luzak B, Rywaniak J, Stanczyk L, et al. Pravastatin and simvastatin improves acetylsalicylic acid-mediated in vitro blood platelet inhibition. Eur J Clin Invest. 2012 Aug;42(8):864-72. PMID: 22409214.

Kassan M, Montero MJ, Sevilla MA. In vitro antioxidant activity of pravastatin provides vascular protection. Eur J Pharmacol. 2010 Mar 25;630(1-3):107-11. PMID: 20044990.

Imamura M, Okunishi K, Ohtsu H, et al. Pravastatin attenuates allergic airway inflammation by suppressing antigen sensitisation, interleukin 17 production and antigen presentation in the lung. Thorax. 2009 Jan;64(1):44-9. PMID: 18835962.

" Not dangerous goods.

LKT P6800 Pravastatin Lactone 100 mg 470.3 Statin; HMG-CoA reductase inhibitor. (βR,δR,1S,2S,6S,8S,8aR)-1,2,6,7,8a-Hexahydro-β,δ,6-trihydroxy-2-methyl-8-[(2S)-2-methyl-1-oxobutoxy]-1-naphthaleneheptanoic acid lactone 85956-22-5 ≥92% 406.51 C23H34O6 CCC(C)C(=O)OC1CC(C=C2C1C(C(C=C2)C)CCC3CC(CC(=O)O3)O)O Ambient 4°C Soluble in water. "Lee SJ, Lee I, Lee J, et al. Statins, 3-hydroxy-3-methylglutaryl coenzyme A reductase inhibitors, potentiate the anti-angiogenic effects of bevacizumab by suppressing angiopoietin2, BiP, and Hsp90α in human colorectal cancer. Br J Cancer. 2014 Jun 19. [Epub ahead of print]. PMID: 24945998.

Wu G, Xie Q, Xu L, et al. Pravastatin inhibits plaque rupture and subsequent thrombus formation in atherosclerotic rabbits with hyperlipidemia. Chem Pharm Bull (Tokyo). 2013;61(2):121-4. PMID: 23207681.

Luzak B, Rywaniak J, Stanczyk L, et al. Pravastatin and simvastatin improves acetylsalicylic acid-mediated in vitro blood platelet inhibition. Eur J Clin Invest. 2012 Aug;42(8):864-72. PMID: 22409214.

Kassan M, Montero MJ, Sevilla MA. In vitro antioxidant activity of pravastatin provides vascular protection. Eur J Pharmacol. 2010 Mar 25;630(1-3):107-11. PMID: 20044990.

Imamura M, Okunishi K, Ohtsu H, et al. Pravastatin attenuates allergic airway inflammation by suppressing antigen sensitisation, interleukin 17 production and antigen presentation in the lung. Thorax. 2009 Jan;64(1):44-9. PMID: 18835962.

" Not dangerous goods.

LKT P1852 Penicillin G procaine 10 g 23.4 Hydrophobic β-lactam; penicillin binding protein inhibitor, potential nAChR antagonist. (2S,5R,6R)-3,3-Dimethyl-7-oxo-6-[( phenoxyacetyl)- amino]-4-Thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid with 2-(diethylamino)ethyl 4-aminobenzoate (1:1) monohydrate Benzylpenicillin Procaine salt; Abbocillin; Duracillin; Pfizerpen-AS 6130-64-9 ≥98% 588.73 C29H38N4O6S H2O CCN(CC)CCOC(=O)C1=CC=C(C=C1)N.CC1(C(N2C(S1)C(C2=O)NC(=O)CC3=CC=CC=C3)C(=O)O)C.O Ambient Ambient Soluble at about 28oC in: water (6.8mg/mL), methanol (>20mg/mL), ethanol (33 mg/mL),  and isopropanol (6.5mg/mL). "Sun S, Selmer M, Andersson DI. Resistance to β-lactam antibiotics conferred by point mutations in penicillin-binding proteins PBP3, PBP4 and PBP6 in Salmonella enterica. PLoS One. 2014 May 8;9(5):e97202. PMID: 24810745.

Schlesinger F, Krampfl K, Haeseler G, et al. Competitive and open channel block of recombinant nAChR channels by different antibiotics. Neuromuscul Disord. 2004 May;14(5):307-12. PMID: 15099589.

Demain AL. Production of beta-lactam antibiotics and its regulation. Proc Natl Sci Counc Repub China B. 1991 Oct;15(4):251-65. PMID: 1815263.

Bär H, Zarnack J. Molecular-biological bases of the mechanism of action of penicillins and cephasporins. Pharmazie. 1970 Jan 1;25(1):10-22. PMID: 4987180.

" Not dangerous goods.

LKT P1852 Penicillin G procaine 25 g 32.4 Hydrophobic β-lactam; penicillin binding protein inhibitor, potential nAChR antagonist. (2S,5R,6R)-3,3-Dimethyl-7-oxo-6-[( phenoxyacetyl)- amino]-4-Thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid with 2-(diethylamino)ethyl 4-aminobenzoate (1:1) monohydrate Benzylpenicillin Procaine salt; Abbocillin; Duracillin; Pfizerpen-AS 6130-64-9 ≥98% 588.73 C29H38N4O6S H2O CCN(CC)CCOC(=O)C1=CC=C(C=C1)N.CC1(C(N2C(S1)C(C2=O)NC(=O)CC3=CC=CC=C3)C(=O)O)C.O Ambient Ambient Soluble at about 28oC in: water (6.8mg/mL), methanol (>20mg/mL), ethanol (33 mg/mL),  and isopropanol (6.5mg/mL). "Sun S, Selmer M, Andersson DI. Resistance to β-lactam antibiotics conferred by point mutations in penicillin-binding proteins PBP3, PBP4 and PBP6 in Salmonella enterica. PLoS One. 2014 May 8;9(5):e97202. PMID: 24810745.

Schlesinger F, Krampfl K, Haeseler G, et al. Competitive and open channel block of recombinant nAChR channels by different antibiotics. Neuromuscul Disord. 2004 May;14(5):307-12. PMID: 15099589.

Demain AL. Production of beta-lactam antibiotics and its regulation. Proc Natl Sci Counc Repub China B. 1991 Oct;15(4):251-65. PMID: 1815263.

Bär H, Zarnack J. Molecular-biological bases of the mechanism of action of penicillins and cephasporins. Pharmazie. 1970 Jan 1;25(1):10-22. PMID: 4987180.

" Not dangerous goods.

LKT P1852 Penicillin G procaine 100 g 92.5 Hydrophobic β-lactam; penicillin binding protein inhibitor, potential nAChR antagonist. (2S,5R,6R)-3,3-Dimethyl-7-oxo-6-[( phenoxyacetyl)- amino]-4-Thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid with 2-(diethylamino)ethyl 4-aminobenzoate (1:1) monohydrate Benzylpenicillin Procaine salt; Abbocillin; Duracillin; Pfizerpen-AS 6130-64-9 ≥98% 588.73 C29H38N4O6S H2O CCN(CC)CCOC(=O)C1=CC=C(C=C1)N.CC1(C(N2C(S1)C(C2=O)NC(=O)CC3=CC=CC=C3)C(=O)O)C.O Ambient Ambient Soluble at about 28oC in: water (6.8mg/mL), methanol (>20mg/mL), ethanol (33 mg/mL),  and isopropanol (6.5mg/mL). "Sun S, Selmer M, Andersson DI. Resistance to β-lactam antibiotics conferred by point mutations in penicillin-binding proteins PBP3, PBP4 and PBP6 in Salmonella enterica. PLoS One. 2014 May 8;9(5):e97202. PMID: 24810745.

Schlesinger F, Krampfl K, Haeseler G, et al. Competitive and open channel block of recombinant nAChR channels by different antibiotics. Neuromuscul Disord. 2004 May;14(5):307-12. PMID: 15099589.

Demain AL. Production of beta-lactam antibiotics and its regulation. Proc Natl Sci Counc Repub China B. 1991 Oct;15(4):251-65. PMID: 1815263.

Bär H, Zarnack J. Molecular-biological bases of the mechanism of action of penicillins and cephasporins. Pharmazie. 1970 Jan 1;25(1):10-22. PMID: 4987180.

" Not dangerous goods.

LKT P1853 Penicillin V Potassium 10 g 27.8 Hydrophobic β-lactam; penicillin binding protein inhibitor. (2S,5R,6R)-3,3-Dimethyl-7-oxo-6-[( phenoxyacetyl)- amino]-4-Thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid monopotassium salt Penicillin V Potassium salt; Antibiocin; Beromycin; Cliacil; Milcopen; Stabicilline 132-98-9 ≥98% 388.48 C16H17KN2O5S CC1(C(N2C(S1)C(C2=O)NC(=O)COC3=CC=CC=C3)C(=O)[O-])C.[K+] Ambient Ambient Soluble in water. "Demain AL. Production of beta-lactam antibiotics and its regulation. Proc Natl Sci Counc Repub China B. 1991 Oct;15(4):251-65. PMID: 1815263.

Bär H, Zarnack J. Molecular-biological bases of the mechanism of action of penicillins and cephasporins. Pharmazie. 1970 Jan 1;25(1):10-22. PMID: 4987180.

" Xn Not dangerous goods.

LKT P1853 Penicillin V Potassium 25 g 46.4 Hydrophobic β-lactam; penicillin binding protein inhibitor. (2S,5R,6R)-3,3-Dimethyl-7-oxo-6-[( phenoxyacetyl)- amino]-4-Thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid monopotassium salt Penicillin V Potassium salt; Antibiocin; Beromycin; Cliacil; Milcopen; Stabicilline 132-98-9 ≥98% 388.48 C16H17KN2O5S CC1(C(N2C(S1)C(C2=O)NC(=O)COC3=CC=CC=C3)C(=O)[O-])C.[K+] Ambient Ambient Soluble in water. "Demain AL. Production of beta-lactam antibiotics and its regulation. Proc Natl Sci Counc Repub China B. 1991 Oct;15(4):251-65. PMID: 1815263.

Bär H, Zarnack J. Molecular-biological bases of the mechanism of action of penicillins and cephasporins. Pharmazie. 1970 Jan 1;25(1):10-22. PMID: 4987180.

" Xn Not dangerous goods.

LKT P1853 Penicillin V Potassium 100 g 115.5 Hydrophobic β-lactam; penicillin binding protein inhibitor. (2S,5R,6R)-3,3-Dimethyl-7-oxo-6-[( phenoxyacetyl)- amino]-4-Thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid monopotassium salt Penicillin V Potassium salt; Antibiocin; Beromycin; Cliacil; Milcopen; Stabicilline 132-98-9 ≥98% 388.48 C16H17KN2O5S CC1(C(N2C(S1)C(C2=O)NC(=O)COC3=CC=CC=C3)C(=O)[O-])C.[K+] Ambient Ambient Soluble in water. "Demain AL. Production of beta-lactam antibiotics and its regulation. Proc Natl Sci Counc Repub China B. 1991 Oct;15(4):251-65. PMID: 1815263.

Bär H, Zarnack J. Molecular-biological bases of the mechanism of action of penicillins and cephasporins. Pharmazie. 1970 Jan 1;25(1):10-22. PMID: 4987180.

" Xn Not dangerous goods.

LKT P5885 Povidone Iodine 50 g 57.8 Polyvinyl pyrrolidone polymer, disinfectant. 1-Ethenyl-2-pyrrolidinone homopolymer compound with iodine Betadine; Isodine; Ultradine    25655-41-8 ≥98% 364.94 C6H9I2NO C=CN1CCCC1=O.II Ambient Ambient Soluble in water and alcohol. Insoluble in most oragnic solvents "Fiorelli A, Pentimalli F, D'Urso V, et al. Antineoplastic activity of povidone-iodine on different mesothelioma cell lines: results of in vitro study. Eur J Cardiothorac Surg. 2014 Jun;45(6):993-1000. PMID: 24394552.

Song M, Zeng L, Hong X, et al. Polyvinyl pyrrolidone promotes DNA cleavage by a ROS-independent and depurination mechanism. Environ Sci Technol. 2013 Mar 19;47(6):2886-91. PMID: 23425130.

Haznar-Garbacz D, Garbacz G, Eisenächer F, et al. A novel liquefied gas based oral controlled release drug delivery system for liquid drug formulations. Eur J Pharm Biopharm. 2012 Jun;81(2):334-8. PMID: 22426133.

Major T Sr, Major M, Bognár C, et al. Clinico-bacteriological examination of Betadine skin disinfectant fluid and liquid soap in hospitalized patients and hospital employees. Ther Hung. 1993;41(3):114-8. PMID: 8202868.

" Not dangerous goods.

LKT P5885 Povidone Iodine 100 g 92.5 Polyvinyl pyrrolidone polymer, disinfectant. 1-Ethenyl-2-pyrrolidinone homopolymer compound with iodine Betadine; Isodine; Ultradine    25655-41-8 ≥98% 364.94 C6H9I2NO C=CN1CCCC1=O.II Ambient Ambient Soluble in water and alcohol. Insoluble in most oragnic solvents "Fiorelli A, Pentimalli F, D'Urso V, et al. Antineoplastic activity of povidone-iodine on different mesothelioma cell lines: results of in vitro study. Eur J Cardiothorac Surg. 2014 Jun;45(6):993-1000. PMID: 24394552.

Song M, Zeng L, Hong X, et al. Polyvinyl pyrrolidone promotes DNA cleavage by a ROS-independent and depurination mechanism. Environ Sci Technol. 2013 Mar 19;47(6):2886-91. PMID: 23425130.

Haznar-Garbacz D, Garbacz G, Eisenächer F, et al. A novel liquefied gas based oral controlled release drug delivery system for liquid drug formulations. Eur J Pharm Biopharm. 2012 Jun;81(2):334-8. PMID: 22426133.

Major T Sr, Major M, Bognár C, et al. Clinico-bacteriological examination of Betadine skin disinfectant fluid and liquid soap in hospitalized patients and hospital employees. Ther Hung. 1993;41(3):114-8. PMID: 8202868.

" Not dangerous goods.

LKT P1854 Penicillic Acid 5 mg 64.2 Neuroactive mycotoxin produced by Penicillum and Aspergillus; BK K+, voltage-gated cardiac Na+, K+, Ca2+ channel inhibitor. 90-65-3 ≥98% 170.16 C8H10O4 CC(=C)C(=O)C(=CC(=O)O)OC Ambient 4°C Water, Ethanol, Dichloromethane. "Oh SY, Balch CG, Cliff RL, et al. Exposure to Penicillium mycotoxins alters gene expression of enzymes involved in the epigenetic regulation of bovine macrophages (BoMacs). Mycotoxin Res. 2013 Nov;29(4):235-43. PMID: 23893597.

Kang SW, Kim SW. New antifungal activity of penicillic acid against Phytophthora species. Biotechnol Lett. 2004 May;26(9):695-8. PMID: 15195966.

Bando M, Hasegawa M, Tsuboi Y, et al. The mycotoxin penicillic acid inhibits Fas ligand-induced apoptosis by blocking self-processing of caspase-8 in death-inducing signaling complex. J Biol Chem. 2003 Feb 21;278(8):5786-93. PMID: 12482880.

Pandiyan V, Nayeem M, Nanjappan K, et al. Penicillic acid as Na+,K+ and Ca2+ channel blocker in isolated frog's heart at toxic levels. Indian J Exp Biol. 1990 Mar;28(3):295-6. PMID: 2163978.

" Xi, Xn, T Not dangerous goods.

LKT P1854 Penicillic Acid 10 mg 172.1 Neuroactive mycotoxin produced by Penicillum and Aspergillus; BK K+, voltage-gated cardiac Na+, K+, Ca2+ channel inhibitor. 90-65-3 ≥98% 170.16 C8H10O4 CC(=C)C(=O)C(=CC(=O)O)OC Ambient 4°C Water, Ethanol, Dichloromethane. "Oh SY, Balch CG, Cliff RL, et al. Exposure to Penicillium mycotoxins alters gene expression of enzymes involved in the epigenetic regulation of bovine macrophages (BoMacs). Mycotoxin Res. 2013 Nov;29(4):235-43. PMID: 23893597.

Kang SW, Kim SW. New antifungal activity of penicillic acid against Phytophthora species. Biotechnol Lett. 2004 May;26(9):695-8. PMID: 15195966.

Bando M, Hasegawa M, Tsuboi Y, et al. The mycotoxin penicillic acid inhibits Fas ligand-induced apoptosis by blocking self-processing of caspase-8 in death-inducing signaling complex. J Biol Chem. 2003 Feb 21;278(8):5786-93. PMID: 12482880.

Pandiyan V, Nayeem M, Nanjappan K, et al. Penicillic acid as Na+,K+ and Ca2+ channel blocker in isolated frog's heart at toxic levels. Indian J Exp Biol. 1990 Mar;28(3):295-6. PMID: 2163978.

" Xi, Xn, T Not dangerous goods.

LKT P1854 Penicillic Acid 50 mg 478 Neuroactive mycotoxin produced by Penicillum and Aspergillus; BK K+, voltage-gated cardiac Na+, K+, Ca2+ channel inhibitor. 90-65-3 ≥98% 170.16 C8H10O4 CC(=C)C(=O)C(=CC(=O)O)OC Ambient 4°C Water, Ethanol, Dichloromethane. "Oh SY, Balch CG, Cliff RL, et al. Exposure to Penicillium mycotoxins alters gene expression of enzymes involved in the epigenetic regulation of bovine macrophages (BoMacs). Mycotoxin Res. 2013 Nov;29(4):235-43. PMID: 23893597.

Kang SW, Kim SW. New antifungal activity of penicillic acid against Phytophthora species. Biotechnol Lett. 2004 May;26(9):695-8. PMID: 15195966.

Bando M, Hasegawa M, Tsuboi Y, et al. The mycotoxin penicillic acid inhibits Fas ligand-induced apoptosis by blocking self-processing of caspase-8 in death-inducing signaling complex. J Biol Chem. 2003 Feb 21;278(8):5786-93. PMID: 12482880.

Pandiyan V, Nayeem M, Nanjappan K, et al. Penicillic acid as Na+,K+ and Ca2+ channel blocker in isolated frog's heart at toxic levels. Indian J Exp Biol. 1990 Mar;28(3):295-6. PMID: 2163978.

" Xi, Xn, T Not dangerous goods.

LKT P5878 Potassium Canrenoate 1 g 46.4 Aldosterone antagonist. (17α)-17-Hydroxy-3-oxopregna-4,6-diene-21- carboxylic acid γ-lactonne free acid potassium salt Canrenoic acid Potassium salt; Kanrenol; Soldactone; Venactone 2181-04-6 ≥98% 396.56 C22H29KO4 CC12CCC(=O)C=C1C=CC3C2CCC4(C3CCC4(CCC(=O)[O-])O)C.[K+] Ambient Ambient Very soluble in water and alcohol. Insoluble in chloroform and ether. "Schmidt K, Tissier R, Ghaleh B, et al. Cardioprotective effects of mineralocorticoid receptor antagonists at reperfusion. Eur Heart J. 2010 Jul;31(13):1655-62. PMID: 20028693.

Rugale C, Cordaillat M, Mimran A, et al. Time-course reduction of renal function in rats on high sodium intake: acute reversal by potassium canrenoate. Clin Exp Pharmacol Physiol. 2008 Apr;35(4):412-5. PMID: 18307731.

Sugiyama A, Satoh Y, Takahara A, et al. Electropharmacological effects of a spironolactone derivative, potassium canrenoate, assessed in the halothane-anesthetized canine model. J Pharmacol Sci. 2004 Dec;96(4):436-43. PMID: 15599107.

Bos R, Mougenot N, Médiani O, et al. Potassium canrenoate, an aldosterone receptor antagonist, reduces isoprenaline-induced cardiac fibrosis in the rat. J Pharmacol Exp Ther. 2004 Jun;309(3):1160-6. PMID: 14764658.

" Xn Not dangerous goods.

LKT P5878 Potassium Canrenoate 5 g 115.5 Aldosterone antagonist. (17α)-17-Hydroxy-3-oxopregna-4,6-diene-21- carboxylic acid γ-lactonne free acid potassium salt Canrenoic acid Potassium salt; Kanrenol; Soldactone; Venactone 2181-04-6 ≥98% 396.56 C22H29KO4 CC12CCC(=O)C=C1C=CC3C2CCC4(C3CCC4(CCC(=O)[O-])O)C.[K+] Ambient Ambient Very soluble in water and alcohol. Insoluble in chloroform and ether. "Schmidt K, Tissier R, Ghaleh B, et al. Cardioprotective effects of mineralocorticoid receptor antagonists at reperfusion. Eur Heart J. 2010 Jul;31(13):1655-62. PMID: 20028693.

Rugale C, Cordaillat M, Mimran A, et al. Time-course reduction of renal function in rats on high sodium intake: acute reversal by potassium canrenoate. Clin Exp Pharmacol Physiol. 2008 Apr;35(4):412-5. PMID: 18307731.

Sugiyama A, Satoh Y, Takahara A, et al. Electropharmacological effects of a spironolactone derivative, potassium canrenoate, assessed in the halothane-anesthetized canine model. J Pharmacol Sci. 2004 Dec;96(4):436-43. PMID: 15599107.

Bos R, Mougenot N, Médiani O, et al. Potassium canrenoate, an aldosterone receptor antagonist, reduces isoprenaline-induced cardiac fibrosis in the rat. J Pharmacol Exp Ther. 2004 Jun;309(3):1160-6. PMID: 14764658.

" Xn Not dangerous goods.

LKT P5878 Potassium Canrenoate 25 g 520 Aldosterone antagonist. (17α)-17-Hydroxy-3-oxopregna-4,6-diene-21- carboxylic acid γ-lactonne free acid potassium salt Canrenoic acid Potassium salt; Kanrenol; Soldactone; Venactone 2181-04-6 ≥98% 396.56 C22H29KO4 CC12CCC(=O)C=C1C=CC3C2CCC4(C3CCC4(CCC(=O)[O-])O)C.[K+] Ambient Ambient Very soluble in water and alcohol. Insoluble in chloroform and ether. "Schmidt K, Tissier R, Ghaleh B, et al. Cardioprotective effects of mineralocorticoid receptor antagonists at reperfusion. Eur Heart J. 2010 Jul;31(13):1655-62. PMID: 20028693.

Rugale C, Cordaillat M, Mimran A, et al. Time-course reduction of renal function in rats on high sodium intake: acute reversal by potassium canrenoate. Clin Exp Pharmacol Physiol. 2008 Apr;35(4):412-5. PMID: 18307731.

Sugiyama A, Satoh Y, Takahara A, et al. Electropharmacological effects of a spironolactone derivative, potassium canrenoate, assessed in the halothane-anesthetized canine model. J Pharmacol Sci. 2004 Dec;96(4):436-43. PMID: 15599107.

Bos R, Mougenot N, Médiani O, et al. Potassium canrenoate, an aldosterone receptor antagonist, reduces isoprenaline-induced cardiac fibrosis in the rat. J Pharmacol Exp Ther. 2004 Jun;309(3):1160-6. PMID: 14764658.

" Xn Not dangerous goods.

LKT P1869 Perindopril Erbumine 100 mg 75 ACE inhibitor. 107133-36-8 ≥95% 441.6 C19H32N2O5 C4H11N CCCC(C(=O)OCC)NC(C)C(=O)N1C2CCCCC2CC1C(=O)O.CC(C)(C)N Ambient Ambient "Yamada K, Horita T, Takayama M, et al. Effect of a centrally active angiotensin converting enzyme inhibitor, perindopril, on cognitive performance in chronic cerebral hypo-perfusion rats. Brain Res. 2011 Nov 3;1421:110-20. PMID: 21981801.

Gao L, Yu DM. Molecular mechanism of limbs' postischemic revascularization improved by perindopril in diabetic rats. Chin Med J (Engl). 2008 Nov 5;121(21):2129-33. PMID: 19080171.

Li X, Meng Y, Yang XS, et al. ACEI attenuates the progression of CCl4-induced rat hepatic fibrogenesis by inhibiting TGF-beta1, PDGF-BB, NF-kappaB and MMP-2,9. World J Gastroenterol. 2005 Aug 21;11(31):4807-11. PMID: 16097048.

Yoshiji H, Kuriyama S, Kawata M, et al. The angiotensin-I-converting enzyme inhibitor perindopril suppresses tumor growth and angiogenesis: possible role of the vascular endothelial growth factor. Clin Cancer Res. 2001 Apr;7(4):1073-8. PMID: 11309359.

Richer C, Doussau MP, Giudicelli JF. Perindopril, a new converting enzyme inhibitor: systemic and regional hemodynamics and sympathoinhibitory effects in spontaneously hypertensive rats. J Cardiovasc Pharmacol. 1986 Mar-Apr;8(2):346-57. PMID: 2422474.

" None Not dangerous goods.

LKT P1869 Perindopril Erbumine 250 mg 149.9 ACE inhibitor. 107133-36-8 ≥95% 441.6 C19H32N2O5 C4H11N CCCC(C(=O)OCC)NC(C)C(=O)N1C2CCCCC2CC1C(=O)O.CC(C)(C)N Ambient Ambient "Yamada K, Horita T, Takayama M, et al. Effect of a centrally active angiotensin converting enzyme inhibitor, perindopril, on cognitive performance in chronic cerebral hypo-perfusion rats. Brain Res. 2011 Nov 3;1421:110-20. PMID: 21981801.

Gao L, Yu DM. Molecular mechanism of limbs' postischemic revascularization improved by perindopril in diabetic rats. Chin Med J (Engl). 2008 Nov 5;121(21):2129-33. PMID: 19080171.

Li X, Meng Y, Yang XS, et al. ACEI attenuates the progression of CCl4-induced rat hepatic fibrogenesis by inhibiting TGF-beta1, PDGF-BB, NF-kappaB and MMP-2,9. World J Gastroenterol. 2005 Aug 21;11(31):4807-11. PMID: 16097048.

Yoshiji H, Kuriyama S, Kawata M, et al. The angiotensin-I-converting enzyme inhibitor perindopril suppresses tumor growth and angiogenesis: possible role of the vascular endothelial growth factor. Clin Cancer Res. 2001 Apr;7(4):1073-8. PMID: 11309359.

Richer C, Doussau MP, Giudicelli JF. Perindopril, a new converting enzyme inhibitor: systemic and regional hemodynamics and sympathoinhibitory effects in spontaneously hypertensive rats. J Cardiovasc Pharmacol. 1986 Mar-Apr;8(2):346-57. PMID: 2422474.

" None Not dangerous goods.

LKT P1869 Perindopril Erbumine 1 g 440.8 ACE inhibitor. 107133-36-8 ≥95% 441.6 C19H32N2O5 C4H11N CCCC(C(=O)OCC)NC(C)C(=O)N1C2CCCCC2CC1C(=O)O.CC(C)(C)N Ambient Ambient "Yamada K, Horita T, Takayama M, et al. Effect of a centrally active angiotensin converting enzyme inhibitor, perindopril, on cognitive performance in chronic cerebral hypo-perfusion rats. Brain Res. 2011 Nov 3;1421:110-20. PMID: 21981801.

Gao L, Yu DM. Molecular mechanism of limbs' postischemic revascularization improved by perindopril in diabetic rats. Chin Med J (Engl). 2008 Nov 5;121(21):2129-33. PMID: 19080171.

Li X, Meng Y, Yang XS, et al. ACEI attenuates the progression of CCl4-induced rat hepatic fibrogenesis by inhibiting TGF-beta1, PDGF-BB, NF-kappaB and MMP-2,9. World J Gastroenterol. 2005 Aug 21;11(31):4807-11. PMID: 16097048.

Yoshiji H, Kuriyama S, Kawata M, et al. The angiotensin-I-converting enzyme inhibitor perindopril suppresses tumor growth and angiogenesis: possible role of the vascular endothelial growth factor. Clin Cancer Res. 2001 Apr;7(4):1073-8. PMID: 11309359.

Richer C, Doussau MP, Giudicelli JF. Perindopril, a new converting enzyme inhibitor: systemic and regional hemodynamics and sympathoinhibitory effects in spontaneously hypertensive rats. J Cardiovasc Pharmacol. 1986 Mar-Apr;8(2):346-57. PMID: 2422474.

" None Not dangerous goods.

LKT P5845 Polydatin 250 mg 94.4 Stilbenoid glucoside found in Polygonum. 3-Hydroxy-5-(2-(4-hydroxyphenyl)ethenyl)phenyl-beta-D-glucoside Resveratrol 3-β-mono-D-glucoside 65914-17-2 ≥97% 390.38 C20H22O8 C1=CC(=CC=C1C=CC2=CC(=CC(=C2)OC3C(C(C(C(O3)CO)O)O)O)O)O Protect from light and heat. Ambient Ambient -70° Soluble in methanol, ethanol acetone, hot water or ethyl acetate. "Zhang Y, Zhuang Z, Meng Q, et al. Polydatin inhibits growth of lung cancer cells by inducing apoptosis and causing cell cycle arrest. Oncol Lett. 2014 Jan;7(1):295-301. PMID: 24348867.

Yang B, Li JJ, Cao JJ, et al. Polydatin attenuated food allergy via store-operated calcium channels in mast cell. World J Gastroenterol. 2013 Jul 7;19(25):3980-9. PMID: 23840142.

Li XH, Gong X, Zhang L, et al. Protective effects of polydatin on septic lung injury in mice via upregulation of HO-1. Mediators Inflamm. 2013;2013:354087. PMID: 23431240.

Wu MJ, Gong X, Jiang R, et al. Polydatin protects against lipopolysaccharide-induced fulminant hepatic failure in D-galactosamine-sensitized mice. Int J Immunopathol Pharmacol. 2012 Oct-Dec;25(4):923-34. PMID: 23298483.

" None Not dangerous goods.

LKT P5845 Polydatin 1 g 209.8 Stilbenoid glucoside found in Polygonum. 3-Hydroxy-5-(2-(4-hydroxyphenyl)ethenyl)phenyl-beta-D-glucoside Resveratrol 3-β-mono-D-glucoside 65914-17-2 ≥97% 390.38 C20H22O8 C1=CC(=CC=C1C=CC2=CC(=CC(=C2)OC3C(C(C(C(O3)CO)O)O)O)O)O Protect from light and heat. Ambient Ambient -70° Soluble in methanol, ethanol acetone, hot water or ethyl acetate. "Zhang Y, Zhuang Z, Meng Q, et al. Polydatin inhibits growth of lung cancer cells by inducing apoptosis and causing cell cycle arrest. Oncol Lett. 2014 Jan;7(1):295-301. PMID: 24348867.

Yang B, Li JJ, Cao JJ, et al. Polydatin attenuated food allergy via store-operated calcium channels in mast cell. World J Gastroenterol. 2013 Jul 7;19(25):3980-9. PMID: 23840142.

Li XH, Gong X, Zhang L, et al. Protective effects of polydatin on septic lung injury in mice via upregulation of HO-1. Mediators Inflamm. 2013;2013:354087. PMID: 23431240.

Wu MJ, Gong X, Jiang R, et al. Polydatin protects against lipopolysaccharide-induced fulminant hepatic failure in D-galactosamine-sensitized mice. Int J Immunopathol Pharmacol. 2012 Oct-Dec;25(4):923-34. PMID: 23298483.

" None Not dangerous goods.

LKT P1917 Phenylethyl 3-methylcaffeate 50 mg 82.8 Derivative of methyl caffeate, hydroxycinnamic acid. "2-Phenylethyl3-(4-hydroxy-3-methoxyphenyl)-2-

propenoate" CCRIS 7791 71835-85-3 ≥97% 298.33 C18H18O4 COC1=C(C=CC(=C1)C=CC(=O)OCCC2=CC=CC=C2)O Store in a cool, dry place. Ambient 4°C Sol in ethanol, methanol, and most organic solvents. "Samaha HS, Kelloff GJ, Steele V, et al. Modulation of apoptosis by sulindac, curcumin, phenylethyl-3-methylcaffeate, and 6-phenylhexyl isothiocyanate: apoptotic index as a biomarker in colon cancer chemoprevention and promotion. Cancer Res. 1997 Apr 1;57(7):1301-5. PMID: 9102217.

Rao CV, Desai D, Rivenson A, et al. Chemoprevention of colon carcinogenesis by phenylethyl-3-methylcaffeate. Cancer Res. 1995 Jun 1;55(11):2310-5. PMID: 7757981.

" Not dangerous goods.

LKT P1917 Phenylethyl 3-methylcaffeate 100 mg 130.2 Derivative of methyl caffeate, hydroxycinnamic acid. "2-Phenylethyl3-(4-hydroxy-3-methoxyphenyl)-2-

propenoate" CCRIS 7791 71835-85-3 ≥97% 298.33 C18H18O4 COC1=C(C=CC(=C1)C=CC(=O)OCCC2=CC=CC=C2)O Store in a cool, dry place. Ambient 4°C Sol in ethanol, methanol, and most organic solvents. "Samaha HS, Kelloff GJ, Steele V, et al. Modulation of apoptosis by sulindac, curcumin, phenylethyl-3-methylcaffeate, and 6-phenylhexyl isothiocyanate: apoptotic index as a biomarker in colon cancer chemoprevention and promotion. Cancer Res. 1997 Apr 1;57(7):1301-5. PMID: 9102217.

Rao CV, Desai D, Rivenson A, et al. Chemoprevention of colon carcinogenesis by phenylethyl-3-methylcaffeate. Cancer Res. 1995 Jun 1;55(11):2310-5. PMID: 7757981.

" Not dangerous goods.

LKT P1917 Phenylethyl 3-methylcaffeate 500 mg 425.9 Derivative of methyl caffeate, hydroxycinnamic acid. "2-Phenylethyl3-(4-hydroxy-3-methoxyphenyl)-2-

propenoate" CCRIS 7791 71835-85-3 ≥97% 298.33 C18H18O4 COC1=C(C=CC(=C1)C=CC(=O)OCCC2=CC=CC=C2)O Store in a cool, dry place. Ambient 4°C Sol in ethanol, methanol, and most organic solvents. "Samaha HS, Kelloff GJ, Steele V, et al. Modulation of apoptosis by sulindac, curcumin, phenylethyl-3-methylcaffeate, and 6-phenylhexyl isothiocyanate: apoptotic index as a biomarker in colon cancer chemoprevention and promotion. Cancer Res. 1997 Apr 1;57(7):1301-5. PMID: 9102217.

Rao CV, Desai D, Rivenson A, et al. Chemoprevention of colon carcinogenesis by phenylethyl-3-methylcaffeate. Cancer Res. 1995 Jun 1;55(11):2310-5. PMID: 7757981.

" Not dangerous goods.

LKT P5712 Podophyllotoxin 50 mg 38.1 Non-alkaloid lignan found in Podophyllum,derivatives of this compound inhibit topoisomerase II. (5R,5aR,8aR,9R)-5,8,8a,9-Tetrahydro-9-hydroxy-5-(3,4,5-trimethoxyphenyl)furo(3',4':6,7)naphtho(2,3-d)- 1,3-dioxol-6(5aH)-one Podofilox; Podophyllinic acid lactone 518-28-5 ≥90% 414.41 C22H22O8 COC1=CC(=CC(=C1OC)OC)C2C3C(COC3=O)C(C4=CC5=C(C=C24)OCO5)O Very hygroscopic. Ambient -20°C Slightly soluble in water. "Ji CF, Ji YB. Apoptosis of human gastric cancer SGC-7901 cells induced by podophyllotoxin. Exp Ther Med. 2014 May;7(5):1317-1322. PMID: 24940431.

Ramírez-Fort MK, Au SC, Javed SA, et al. Management of cutaneous human papillomavirus infection: pharmacotherapies. Curr Probl Dermatol. 2014;45:175-85. PMID: 24643186.

Li J, Dai CX, Sun H, et al. Protective effects and mechanisms of curcumin on podophyllotoxin toxicity in vitro and in vivo. Toxicol Appl Pharmacol. 2012 Dec 1;265(2):190-9. PMID: 23088858.

" T "UN number: 3462     Class: 6.1     Packing Group: II

Proper shipping name: Toxins, extracted from living sources, solid, n.o.s. (Podophyllotoxin)"

LKT P5712 Podophyllotoxin 100 mg 47.6 Non-alkaloid lignan found in Podophyllum,derivatives of this compound inhibit topoisomerase II. (5R,5aR,8aR,9R)-5,8,8a,9-Tetrahydro-9-hydroxy-5-(3,4,5-trimethoxyphenyl)furo(3',4':6,7)naphtho(2,3-d)- 1,3-dioxol-6(5aH)-one Podofilox; Podophyllinic acid lactone 518-28-5 ≥90% 414.41 C22H22O8 COC1=CC(=CC(=C1OC)OC)C2C3C(COC3=O)C(C4=CC5=C(C=C24)OCO5)O Very hygroscopic. Ambient -20°C Slightly soluble in water. "Ji CF, Ji YB. Apoptosis of human gastric cancer SGC-7901 cells induced by podophyllotoxin. Exp Ther Med. 2014 May;7(5):1317-1322. PMID: 24940431.

Ramírez-Fort MK, Au SC, Javed SA, et al. Management of cutaneous human papillomavirus infection: pharmacotherapies. Curr Probl Dermatol. 2014;45:175-85. PMID: 24643186.

Li J, Dai CX, Sun H, et al. Protective effects and mechanisms of curcumin on podophyllotoxin toxicity in vitro and in vivo. Toxicol Appl Pharmacol. 2012 Dec 1;265(2):190-9. PMID: 23088858.

" T "UN number: 3462     Class: 6.1     Packing Group: II

Proper shipping name: Toxins, extracted from living sources, solid, n.o.s. (Podophyllotoxin)"

LKT P1952 Penitrem A 1 mg 75 Neuroactive mycotoxin produced by Penicillum and Aspergillus; GABA-A potentiator, BK K+ channel inhibitor. Tremortin A 12627-35-9 ≥98% 634.2 C37H44ClNO6 CC(=C)C1C(C2C3(O2)C(O1)CCC4(C3(CCC5C4(C6=C7C5OC(C8CC9C8(C1=C7C(=CC(=C1CC9=C)Cl)N6)O)(C)C)C)O)C)O Ambient 4°C Acetone, Methanol, and DMSO. "Moldes-Anaya A, Rundberget T, Fæste CK, et al. Neurotoxicity of Penicillium crustosum secondary metabolites: tremorgenic activity of orally administered penitrem A and thomitrem A and E in mice. Toxicon. 2012 Dec 15;60(8):1428-35. PMID: 23085423.

Asano S, Bratz IN, Berwick ZC, et al. Penitrem A as a tool for understanding the role of large conductance Ca(2+)/voltage-sensitive K(+) channels in vascular function. J Pharmacol Exp Ther. 2012 Aug;342(2):453-60. PMID: 22580348.

Moldes-Anaya AS, Fonnum F, Eriksen GS, et al. In vitro neuropharmacological evaluation of penitrem-induced tremorgenic syndromes: importance of the GABAergic system. Neurochem Int. 2011 Dec;59(7):1074-81. PMID: 21924313.

Deschaux O, Bizot JC. Effects of penitrem A on rat's performances in passive avoidance and Morris water maze tests. Mycopathologia. 1997;138(2):99-104. PMID: 9433810.

" T+ "UN number: 2811     Class: 6.1     Packing Group: II

Proper shipping name: Toxic solid, organic, n.o.s. (Penitrem A)"

LKT P1952 Penitrem A 5 mg 359.9 Neuroactive mycotoxin produced by Penicillum and Aspergillus; GABA-A potentiator, BK K+ channel inhibitor. Tremortin A 12627-35-9 ≥98% 634.2 C37H44ClNO6 CC(=C)C1C(C2C3(O2)C(O1)CCC4(C3(CCC5C4(C6=C7C5OC(C8CC9C8(C1=C7C(=CC(=C1CC9=C)Cl)N6)O)(C)C)C)O)C)O Ambient 4°C Acetone, Methanol, and DMSO. "Moldes-Anaya A, Rundberget T, Fæste CK, et al. Neurotoxicity of Penicillium crustosum secondary metabolites: tremorgenic activity of orally administered penitrem A and thomitrem A and E in mice. Toxicon. 2012 Dec 15;60(8):1428-35. PMID: 23085423.

Asano S, Bratz IN, Berwick ZC, et al. Penitrem A as a tool for understanding the role of large conductance Ca(2+)/voltage-sensitive K(+) channels in vascular function. J Pharmacol Exp Ther. 2012 Aug;342(2):453-60. PMID: 22580348.

Moldes-Anaya AS, Fonnum F, Eriksen GS, et al. In vitro neuropharmacological evaluation of penitrem-induced tremorgenic syndromes: importance of the GABAergic system. Neurochem Int. 2011 Dec;59(7):1074-81. PMID: 21924313.

Deschaux O, Bizot JC. Effects of penitrem A on rat's performances in passive avoidance and Morris water maze tests. Mycopathologia. 1997;138(2):99-104. PMID: 9433810.

" T+ "UN number: 2811     Class: 6.1     Packing Group: II

Proper shipping name: Toxic solid, organic, n.o.s. (Penitrem A)"

LKT P5712 Podophyllotoxin 500 mg 190.3 Non-alkaloid lignan found in Podophyllum,derivatives of this compound inhibit topoisomerase II. (5R,5aR,8aR,9R)-5,8,8a,9-Tetrahydro-9-hydroxy-5-(3,4,5-trimethoxyphenyl)furo(3',4':6,7)naphtho(2,3-d)- 1,3-dioxol-6(5aH)-one Podofilox; Podophyllinic acid lactone 518-28-5 ≥90% 414.41 C22H22O8 COC1=CC(=CC(=C1OC)OC)C2C3C(COC3=O)C(C4=CC5=C(C=C24)OCO5)O Very hygroscopic. Ambient -20°C Slightly soluble in water. "Ji CF, Ji YB. Apoptosis of human gastric cancer SGC-7901 cells induced by podophyllotoxin. Exp Ther Med. 2014 May;7(5):1317-1322. PMID: 24940431.

Ramírez-Fort MK, Au SC, Javed SA, et al. Management of cutaneous human papillomavirus infection: pharmacotherapies. Curr Probl Dermatol. 2014;45:175-85. PMID: 24643186.

Li J, Dai CX, Sun H, et al. Protective effects and mechanisms of curcumin on podophyllotoxin toxicity in vitro and in vivo. Toxicol Appl Pharmacol. 2012 Dec 1;265(2):190-9. PMID: 23088858.

" T "UN number: 3462     Class: 6.1     Packing Group: II

Proper shipping name: Toxins, extracted from living sources, solid, n.o.s. (Podophyllotoxin)"

LKT P1955 Pentagastrin 1 mg 132 Synthetic peptide, stimulates gastric acid secretion. (3S)-4-[[(2S)-1-amino-1-oxo-3-phenylpropan-2-yl]amino]-3-[[(2S)-2-[[(2S)-3-(1H-indol-3-yl)-2-[3-(2-methylpropoxycarbonylamino)propanoylamino]propanoyl]amino]-4-methylsulfanylbutanoyl]amino]-4-oxobutanoic acid Gastrodiagnost, Pentagastrinum, Peptavlon, Petogasrin 5534-95-2 ≥95% 768.79 C37H50N7O9S1 CC(C)(C)OC(=O)NCCC(=O)NC(CC1=CNC2=CC=CC=C21)C(=O)NC(CCSC)C(=O)NC(CC(=O)O)C(=O)NC(CC3=CC=CC=C3)C(=O)N Ambient -20°C "Beckert S, Wolf SC, Farrahi F, et al. TGF-beta3 inhibits pentagastrin-stimulated gastric acid secretion in rats. Med Sci Monit. 2005 Mar;11(3):BR80-3. PMID: 15735558.

Yamamoto O, Matsunaga Y, Shiba Y, et al. Inhibition of motilin-induced phase III contractions by pentagastrin in Heidenhain pouch dogs. J Pharmacol Exp Ther. 1994 Dec;271(3):1471-6. PMID: 7996460.

Nishizaki Y, Guth PH, Kim G, et al. Pentagastrin enhances gastric mucosal defenses in vivo: luminal acid-dependent and independent effects. Am J Physiol. 1994 Jul;267(1 Pt 1):G94-104. PMID: 8048536.

Zwick R, Bowes KL, Daniel EE, et al. Mechanism of action of pentagastrin on the lower esophageal sphincter. J Clin Invest. 1976 Jun;57(6):1644-51. PMID: 932198.

" Repr. Cat. 1, Repr. Cat. 2, Xi, Xn Not dangerous goods.

LKT P1955 Pentagastrin 2 mg 225 Synthetic peptide, stimulates gastric acid secretion. (3S)-4-[[(2S)-1-amino-1-oxo-3-phenylpropan-2-yl]amino]-3-[[(2S)-2-[[(2S)-3-(1H-indol-3-yl)-2-[3-(2-methylpropoxycarbonylamino)propanoylamino]propanoyl]amino]-4-methylsulfanylbutanoyl]amino]-4-oxobutanoic acid Gastrodiagnost, Pentagastrinum, Peptavlon, Petogasrin 5534-95-2 ≥95% 768.79 C37H50N7O9S1 CC(C)(C)OC(=O)NCCC(=O)NC(CC1=CNC2=CC=CC=C21)C(=O)NC(CCSC)C(=O)NC(CC(=O)O)C(=O)NC(CC3=CC=CC=C3)C(=O)N Ambient -20°C "Beckert S, Wolf SC, Farrahi F, et al. TGF-beta3 inhibits pentagastrin-stimulated gastric acid secretion in rats. Med Sci Monit. 2005 Mar;11(3):BR80-3. PMID: 15735558.

Yamamoto O, Matsunaga Y, Shiba Y, et al. Inhibition of motilin-induced phase III contractions by pentagastrin in Heidenhain pouch dogs. J Pharmacol Exp Ther. 1994 Dec;271(3):1471-6. PMID: 7996460.

Nishizaki Y, Guth PH, Kim G, et al. Pentagastrin enhances gastric mucosal defenses in vivo: luminal acid-dependent and independent effects. Am J Physiol. 1994 Jul;267(1 Pt 1):G94-104. PMID: 8048536.

Zwick R, Bowes KL, Daniel EE, et al. Mechanism of action of pentagastrin on the lower esophageal sphincter. J Clin Invest. 1976 Jun;57(6):1644-51. PMID: 932198.

" Repr. Cat. 1, Repr. Cat. 2, Xi, Xn Not dangerous goods.

LKT P1955 Pentagastrin 5 mg 396.1 Synthetic peptide, stimulates gastric acid secretion. (3S)-4-[[(2S)-1-amino-1-oxo-3-phenylpropan-2-yl]amino]-3-[[(2S)-2-[[(2S)-3-(1H-indol-3-yl)-2-[3-(2-methylpropoxycarbonylamino)propanoylamino]propanoyl]amino]-4-methylsulfanylbutanoyl]amino]-4-oxobutanoic acid Gastrodiagnost, Pentagastrinum, Peptavlon, Petogasrin 5534-95-2 ≥95% 768.79 C37H50N7O9S1 CC(C)(C)OC(=O)NCCC(=O)NC(CC1=CNC2=CC=CC=C21)C(=O)NC(CCSC)C(=O)NC(CC(=O)O)C(=O)NC(CC3=CC=CC=C3)C(=O)N Ambient -20°C "Beckert S, Wolf SC, Farrahi F, et al. TGF-beta3 inhibits pentagastrin-stimulated gastric acid secretion in rats. Med Sci Monit. 2005 Mar;11(3):BR80-3. PMID: 15735558.

Yamamoto O, Matsunaga Y, Shiba Y, et al. Inhibition of motilin-induced phase III contractions by pentagastrin in Heidenhain pouch dogs. J Pharmacol Exp Ther. 1994 Dec;271(3):1471-6. PMID: 7996460.

Nishizaki Y, Guth PH, Kim G, et al. Pentagastrin enhances gastric mucosal defenses in vivo: luminal acid-dependent and independent effects. Am J Physiol. 1994 Jul;267(1 Pt 1):G94-104. PMID: 8048536.

Zwick R, Bowes KL, Daniel EE, et al. Mechanism of action of pentagastrin on the lower esophageal sphincter. J Clin Invest. 1976 Jun;57(6):1644-51. PMID: 932198.

" Repr. Cat. 1, Repr. Cat. 2, Xi, Xn Not dangerous goods.

LKT P4560 Proteolipid Protein (139-151) 1 mg 180 Immunodominant peptide fragment of PLP, used to induce EAE. PLP ≥95% 1521.7 C72H104N20O17 Ambient -20°C "Soellner IA, Rabe J, Mauri V, et al. Differential aspects of immune cell infiltration and neurodegeneration in acute and relapse experimental autoimmune encephalomyelitis. Clin Immunol. 2013 Dec;149(3):519-29. PMID: 24239839.

Nicolò C, Sali M, Di Sante G, et al. Mycobacterium smegmatis expressing a chimeric protein MPT64-proteolipid protein (PLP) 139-151 reorganizes the PLP-specific T cell repertoire favoring a CD8-mediated response and induces a relapsing experimental autoimmune encephalomyelitis. J Immunol. 2010 Jan 1;184(1):222-35. PMID: 19949067.

" Not dangerous goods.

LKT P2303 Phallacidin 1 mg 339.8 Phallotoxin found in Amanita phalloides; microtubule depolymerization inhibitor. "cyclic(L-Alanyl-2-mercapto-L-tryptophyl-4,5-dihydroxy-L-leucyl-L-valyl-erythro-3-hydroxy-D-alpha-aspartyl-L-cysteinyl-cis-4-hydroxy-L-prolyl) cyclic (2-6)-sulfide 

" Falacidin 26645-35-2 ≥98% 846.91 C37H50N8O13S CC1C(=O)NC2CC3=C(NC4=CC=CC=C34)SCC(C(=O)N5CC(CC5C(=O)N1)O)NC(=O)C(NC(=O)C(NC(=O)C(NC2=O)CC(C)(CO)O)C(C)C)C(C(=O)O)O Protect from light. Ambient 4°C Soluble in DMSO, methanol, water or dimethyl formamide. "Schmid E, Gu S, Yang W, et al. Serum- and glucocorticoid-inducible kinase SGK1 regulates reorganization of actin cytoskeleton in mast cells upon degranulation. Am J Physiol Cell Physiol. 2013 Jan 1;304(1):C49-55. PMID: 23015548.

Zalavary S, Bengtsson T. Adenosine inhibits actin dynamics in human neutrophils: evidence for the involvement of cAMP. Eur J Cell Biol. 1998 Feb;75(2):128-39. PMID: 9548370.

" T+ "UN number: 2811     Class:  6.1     Packing group:  II

Proper shipping name:  Toxic solids, organic, n.o.s. (Phallacidin)

Poison inhalation hazard:  No."

LKT P2303 Phallacidin 5 mg 1213.4 Phallotoxin found in Amanita phalloides; microtubule depolymerization inhibitor. "cyclic(L-Alanyl-2-mercapto-L-tryptophyl-4,5-dihydroxy-L-leucyl-L-valyl-erythro-3-hydroxy-D-alpha-aspartyl-L-cysteinyl-cis-4-hydroxy-L-prolyl) cyclic (2-6)-sulfide 

" Falacidin 26645-35-2 ≥98% 846.91 C37H50N8O13S CC1C(=O)NC2CC3=C(NC4=CC=CC=C34)SCC(C(=O)N5CC(CC5C(=O)N1)O)NC(=O)C(NC(=O)C(NC(=O)C(NC2=O)CC(C)(CO)O)C(C)C)C(C(=O)O)O Protect from light. Ambient 4°C Soluble in DMSO, methanol, water or dimethyl formamide. "Schmid E, Gu S, Yang W, et al. Serum- and glucocorticoid-inducible kinase SGK1 regulates reorganization of actin cytoskeleton in mast cells upon degranulation. Am J Physiol Cell Physiol. 2013 Jan 1;304(1):C49-55. PMID: 23015548.

Zalavary S, Bengtsson T. Adenosine inhibits actin dynamics in human neutrophils: evidence for the involvement of cAMP. Eur J Cell Biol. 1998 Feb;75(2):128-39. PMID: 9548370.

" T+ "UN number: 2811     Class:  6.1     Packing group:  II

Proper shipping name:  Toxic solids, organic, n.o.s. (Phallacidin)

Poison inhalation hazard:  No."

LKT P4560 Proteolipid Protein (139-151) 5 mg 690.2 Immunodominant peptide fragment of PLP, used to induce EAE. PLP ≥95% 1521.7 C72H104N20O17 Ambient -20°C "Soellner IA, Rabe J, Mauri V, et al. Differential aspects of immune cell infiltration and neurodegeneration in acute and relapse experimental autoimmune encephalomyelitis. Clin Immunol. 2013 Dec;149(3):519-29. PMID: 24239839.

Nicolò C, Sali M, Di Sante G, et al. Mycobacterium smegmatis expressing a chimeric protein MPT64-proteolipid protein (PLP) 139-151 reorganizes the PLP-specific T cell repertoire favoring a CD8-mediated response and induces a relapsing experimental autoimmune encephalomyelitis. J Immunol. 2010 Jan 1;184(1):222-35. PMID: 19949067.

" Not dangerous goods.

LKT P4403 Plasminogen Activator Inhibitor 1 0.5 mg 60 Endogenous peptide, produced by activation of PAR1; protease inhibitor. PAI-1 ≥95% 673.79 C27H47N9O9S Ambient -20°C "Gomes Giacoia E, Miyake M, Lawton A, et al. PAI-1 Leads to G1-phase Cell Cycle Progression through Cyclin D3/CDK4/6 Up-regulation. Mol Cancer Res. 2014 Jan 24. [Epub ahead of print]. PMID: 24464915.

Tamura Y, Kawao N, Okada K, et al. Plasminogen activator inhibitor-1 is involved in streptozotocin-induced bone loss in female mice. Diabetes. 2013 Sep;62(9):3170-9. PMID: 23715621.

Zhang YP, Wang WL, Liu J, et al. Plasminogen activator inhibitor-1 promotes the proliferation and inhibits the apoptosis of pulmonary fibroblasts by Ca(2+) signaling. Thromb Res. 2013 Jan;131(1):64-71. PMID: 23021499.

Fang H, Placencio VR, DeClerck YA. Protumorigenic activity of plasminogen activator inhibitor-1 through an antiapoptotic function. J Natl Cancer Inst. 2012 Oct 3;104(19):1470-84. PMID: 22984202.

McEachron TA, Church FC, Mackman N. Regulation of thrombin-induced plasminogen activator inhibitor-1 in 4T1 murine breast cancer cells. Blood Coagul Fibrinolysis. 2011 Oct;22(7):576-82. PMID: 21799402.

" Not dangerous goods.

LKT P4403 Plasminogen Activator Inhibitor 1 1 mg 101.9 Endogenous peptide, produced by activation of PAR1; protease inhibitor. PAI-1 ≥95% 673.79 C27H47N9O9S Ambient -20°C "Gomes Giacoia E, Miyake M, Lawton A, et al. PAI-1 Leads to G1-phase Cell Cycle Progression through Cyclin D3/CDK4/6 Up-regulation. Mol Cancer Res. 2014 Jan 24. [Epub ahead of print]. PMID: 24464915.

Tamura Y, Kawao N, Okada K, et al. Plasminogen activator inhibitor-1 is involved in streptozotocin-induced bone loss in female mice. Diabetes. 2013 Sep;62(9):3170-9. PMID: 23715621.

Zhang YP, Wang WL, Liu J, et al. Plasminogen activator inhibitor-1 promotes the proliferation and inhibits the apoptosis of pulmonary fibroblasts by Ca(2+) signaling. Thromb Res. 2013 Jan;131(1):64-71. PMID: 23021499.

Fang H, Placencio VR, DeClerck YA. Protumorigenic activity of plasminogen activator inhibitor-1 through an antiapoptotic function. J Natl Cancer Inst. 2012 Oct 3;104(19):1470-84. PMID: 22984202.

McEachron TA, Church FC, Mackman N. Regulation of thrombin-induced plasminogen activator inhibitor-1 in 4T1 murine breast cancer cells. Blood Coagul Fibrinolysis. 2011 Oct;22(7):576-82. PMID: 21799402.

" Not dangerous goods.

LKT P4403 Plasminogen Activator Inhibitor 1 2.5 mg 180 Endogenous peptide, produced by activation of PAR1; protease inhibitor. PAI-1 ≥95% 673.79 C27H47N9O9S Ambient -20°C "Gomes Giacoia E, Miyake M, Lawton A, et al. PAI-1 Leads to G1-phase Cell Cycle Progression through Cyclin D3/CDK4/6 Up-regulation. Mol Cancer Res. 2014 Jan 24. [Epub ahead of print]. PMID: 24464915.

Tamura Y, Kawao N, Okada K, et al. Plasminogen activator inhibitor-1 is involved in streptozotocin-induced bone loss in female mice. Diabetes. 2013 Sep;62(9):3170-9. PMID: 23715621.

Zhang YP, Wang WL, Liu J, et al. Plasminogen activator inhibitor-1 promotes the proliferation and inhibits the apoptosis of pulmonary fibroblasts by Ca(2+) signaling. Thromb Res. 2013 Jan;131(1):64-71. PMID: 23021499.

Fang H, Placencio VR, DeClerck YA. Protumorigenic activity of plasminogen activator inhibitor-1 through an antiapoptotic function. J Natl Cancer Inst. 2012 Oct 3;104(19):1470-84. PMID: 22984202.

McEachron TA, Church FC, Mackman N. Regulation of thrombin-induced plasminogen activator inhibitor-1 in 4T1 murine breast cancer cells. Blood Coagul Fibrinolysis. 2011 Oct;22(7):576-82. PMID: 21799402.

" Not dangerous goods.

LKT P4008 PKC412 1 mg 176.2 Staurosporine derivative; PKC and FLT3 inhibitor. Midostaurin; 4'-N-Benzoyl staurosporine 120685-11-2 ≥98% 570.64 C35H30N4O4 CC12C(C(CC(O1)N3C4=CC=CC=C4C5=C6C(=C7C8=CC=CC=C8N2C7=C53)CNC6=O)N(C)C(=O)C9=CC=CC=C9)OC Ambient 4°C DMSO, Dichloromethanol "Fischer T, Stone RM, Deangelo DJ, et al. Phase IIB trial of oral Midostaurin (PKC412), the FMS-like tyrosine kinase 3 receptor (FLT3) and multi-targeted kinase inhibitor, in patients with acute myeloid leukemia and high-risk myelodysplastic syndrome with either wild-type or mutated FLT3. J Clin Oncol. 2010 Oct 1;28(28):4339-45. PMID: 20733134.

Huang YC, Shieh HR, Chen YJ. Midostaurin (PKC412) modulates differentiation and maturation of human myeloid dendritic cells. Toxicol In Vitro. 2010 Sep;24(6):1705-10. PMID: 20685248.

Stölzel F, Steudel C, Oelschlägel U, et al. Mechanisms of resistance against PKC412 in resistant FLT3-ITD positive human acute myeloid leukemia cells. Ann Hematol. 2010 Jul;89(7):653-62. PMID: 20119833.

Nakazono-Kusaba A, Takahashi-Yanaga F, Miwa Y, et al. PKC412 induces apoptosis through a caspase-dependent mechanism in human keloid-derived fibroblasts. Eur J Pharmacol. 2004 Aug 23;497(2):155-60. PMID: 15306200.

Yoshikawa N, Nakamura K, Yamaguchi Y, et al. Effect of PKC412, a selective inhibitor of protein kinase C, on lung metastasis in mice injected with B16 melanoma cells. Life Sci. 2003 Feb 7;72(12):1377-87. PMID: 12527035.

" Not dangerous goods.

LKT P2304 Phalloidin 1 mg 273.1 Phallotoxin found in Amanita phalloides; microtubule depolymerization inhibitor. "Cyclic(L-alanyl-D-threonyl-L-cysteinyl-cis-4-hydroxy-L-

prolyl-L-alanyl-2-mercapto-L-tryptophyl-4,5-dihydroxy-L-

leucyl), cyclic (3,6)-sulfide 

" Phalloidine 17466-45-4 ≥95% 788.87 C35H48N8O11S CC1C(=O)NC2CC3=C(NC4=CC=CC=C34)SCC(C(=O)N5CC(CC5C(=O)N1)O)NC(=O)C(NC(=O)C(NC(=O)C(NC2=O)CC(C)(CO)O)C)C(C)O Stable, but incompatible with strong oxidizing agents. Ambient 4°C Soluble in methanol, ethanol, butanol, pyridine or hot water. "Cooper JA. Effects of cytochalasin and phalloidin on actin. J Cell Biol. 1987 Oct;105(4):1473-8. PMID: 3312229.

Barden JA, Miki M, Hambly BD, et al. Localization of the phalloidin and nucleotide-binding sites on actin. Eur J Biochem. 1987 Feb 2;162(3):583-8. PMID: 3830158.

" T+ "UN number: 3462     Class:  6.1     Packing group:  II

Proper shipping name:  Toxins, extracted from living sources, solid, n.o.s. (Phallodin)

Marine pollutant:  No  Poison Inhalation Hazard:  No."

LKT P2304 Phalloidin 5 mg 1155.2 Phallotoxin found in Amanita phalloides; microtubule depolymerization inhibitor. "Cyclic(L-alanyl-D-threonyl-L-cysteinyl-cis-4-hydroxy-L-

prolyl-L-alanyl-2-mercapto-L-tryptophyl-4,5-dihydroxy-L-

leucyl), cyclic (3,6)-sulfide 

" Phalloidine 17466-45-4 ≥95% 788.87 C35H48N8O11S CC1C(=O)NC2CC3=C(NC4=CC=CC=C34)SCC(C(=O)N5CC(CC5C(=O)N1)O)NC(=O)C(NC(=O)C(NC(=O)C(NC2=O)CC(C)(CO)O)C)C(C)O Stable, but incompatible with strong oxidizing agents. Ambient 4°C Soluble in methanol, ethanol, butanol, pyridine or hot water. "Cooper JA. Effects of cytochalasin and phalloidin on actin. J Cell Biol. 1987 Oct;105(4):1473-8. PMID: 3312229.

Barden JA, Miki M, Hambly BD, et al. Localization of the phalloidin and nucleotide-binding sites on actin. Eur J Biochem. 1987 Feb 2;162(3):583-8. PMID: 3830158.

" T+ "UN number: 3462     Class:  6.1     Packing group:  II

Proper shipping name:  Toxins, extracted from living sources, solid, n.o.s. (Phallodin)

Marine pollutant:  No  Poison Inhalation Hazard:  No."

LKT P4008 PKC412 5 mg 704.7 Staurosporine derivative; PKC and FLT3 inhibitor. Midostaurin; 4'-N-Benzoyl staurosporine 120685-11-2 ≥98% 570.64 C35H30N4O4 CC12C(C(CC(O1)N3C4=CC=CC=C4C5=C6C(=C7C8=CC=CC=C8N2C7=C53)CNC6=O)N(C)C(=O)C9=CC=CC=C9)OC Ambient 4°C DMSO, Dichloromethanol "Fischer T, Stone RM, Deangelo DJ, et al. Phase IIB trial of oral Midostaurin (PKC412), the FMS-like tyrosine kinase 3 receptor (FLT3) and multi-targeted kinase inhibitor, in patients with acute myeloid leukemia and high-risk myelodysplastic syndrome with either wild-type or mutated FLT3. J Clin Oncol. 2010 Oct 1;28(28):4339-45. PMID: 20733134.

Huang YC, Shieh HR, Chen YJ. Midostaurin (PKC412) modulates differentiation and maturation of human myeloid dendritic cells. Toxicol In Vitro. 2010 Sep;24(6):1705-10. PMID: 20685248.

Stölzel F, Steudel C, Oelschlägel U, et al. Mechanisms of resistance against PKC412 in resistant FLT3-ITD positive human acute myeloid leukemia cells. Ann Hematol. 2010 Jul;89(7):653-62. PMID: 20119833.

Nakazono-Kusaba A, Takahashi-Yanaga F, Miwa Y, et al. PKC412 induces apoptosis through a caspase-dependent mechanism in human keloid-derived fibroblasts. Eur J Pharmacol. 2004 Aug 23;497(2):155-60. PMID: 15306200.

Yoshikawa N, Nakamura K, Yamaguchi Y, et al. Effect of PKC412, a selective inhibitor of protein kinase C, on lung metastasis in mice injected with B16 melanoma cells. Life Sci. 2003 Feb 7;72(12):1377-87. PMID: 12527035.

" Not dangerous goods.

LKT P2400 Phenethyl Caffeate 50 mg 86.2 Found in propolis; 5-lipoxygenase inhibitor. 3-(3,4-Dihydroxyphenyl)-2-propenoic acid phenylethyl ester 3,4-Dihydroxycinnamic acid phenethyl ester;  caffeic acid phenethyl ester; CAPE 104594-70-9 ≥98% 284.31 C17H16O4 C1=CC=C(C=C1)CCOC(=O)C=CC2=CC(=C(C=C2)O)O Ambient -20°C Insoluble in water. Soluble in DMSO, or ethanol. "Yang JW, Jung WK, Lee CM, et al. Caffeic acid phenethyl ester inhibits the inflammatory effects of interleukin-1β in human corneal fibroblasts. Immunopharmacol Immunotoxicol. 2014 Oct;36(5):371-7. PMID: 25151996.

Ilhan S, Yılmaz N, Nacar E, et al. The effect of caffeic acid phenethyl ester on isoproterenol-induced myocardial injury in hypertensive rats. Anadolu Kardiyol Derg. 2014 Jun 3. [Epub ahead of print]. PMID: 25036319.

Chiang EP, Tsai SY, Kuo YH, et al. Caffeic acid derivatives inhibit the growth of colon cancer: involvement of the PI3-K/Akt and AMPK signaling pathways. PLoS One. 2014 Jun 24;9(6):e99631. PMID: 24960186.

Shin SH, Seo SG, Min S, et al. Caffeic acid phenethyl ester, a major component of propolis, suppresses high fat diet-induced obesity through inhibiting adipogenesis at the mitotic clonal expansion stage. J Agric Food Chem. 2014 May 14;62(19):4306-12. PMID: 24611533.

Hassan NA, El-Bassossy HM, Mahmoud MF, et al. Caffeic acid phenethyl ester, a 5-lipoxygenase enzyme inhibitor, alleviates diabetic atherosclerotic manifestations: effect on vascular reactivity and stiffness. Chem Biol Interact. 2014 Apr 25;213:28-36. PMID: 24508943.

" Xi Not dangerous goods.

LKT P2400 Phenethyl Caffeate 100 mg 136.2 Found in propolis; 5-lipoxygenase inhibitor. 3-(3,4-Dihydroxyphenyl)-2-propenoic acid phenylethyl ester 3,4-Dihydroxycinnamic acid phenethyl ester;  caffeic acid phenethyl ester; CAPE 104594-70-9 ≥98% 284.31 C17H16O4 C1=CC=C(C=C1)CCOC(=O)C=CC2=CC(=C(C=C2)O)O Ambient -20°C Insoluble in water. Soluble in DMSO, or ethanol. "Yang JW, Jung WK, Lee CM, et al. Caffeic acid phenethyl ester inhibits the inflammatory effects of interleukin-1β in human corneal fibroblasts. Immunopharmacol Immunotoxicol. 2014 Oct;36(5):371-7. PMID: 25151996.

Ilhan S, Yılmaz N, Nacar E, et al. The effect of caffeic acid phenethyl ester on isoproterenol-induced myocardial injury in hypertensive rats. Anadolu Kardiyol Derg. 2014 Jun 3. [Epub ahead of print]. PMID: 25036319.

Chiang EP, Tsai SY, Kuo YH, et al. Caffeic acid derivatives inhibit the growth of colon cancer: involvement of the PI3-K/Akt and AMPK signaling pathways. PLoS One. 2014 Jun 24;9(6):e99631. PMID: 24960186.

Shin SH, Seo SG, Min S, et al. Caffeic acid phenethyl ester, a major component of propolis, suppresses high fat diet-induced obesity through inhibiting adipogenesis at the mitotic clonal expansion stage. J Agric Food Chem. 2014 May 14;62(19):4306-12. PMID: 24611533.

Hassan NA, El-Bassossy HM, Mahmoud MF, et al. Caffeic acid phenethyl ester, a 5-lipoxygenase enzyme inhibitor, alleviates diabetic atherosclerotic manifestations: effect on vascular reactivity and stiffness. Chem Biol Interact. 2014 Apr 25;213:28-36. PMID: 24508943.

" Xi Not dangerous goods.

LKT P2400 Phenethyl Caffeate 500 mg 446.9 Found in propolis; 5-lipoxygenase inhibitor. 3-(3,4-Dihydroxyphenyl)-2-propenoic acid phenylethyl ester 3,4-Dihydroxycinnamic acid phenethyl ester;  caffeic acid phenethyl ester; CAPE 104594-70-9 ≥98% 284.31 C17H16O4 C1=CC=C(C=C1)CCOC(=O)C=CC2=CC(=C(C=C2)O)O Ambient -20°C Insoluble in water. Soluble in DMSO, or ethanol. "Yang JW, Jung WK, Lee CM, et al. Caffeic acid phenethyl ester inhibits the inflammatory effects of interleukin-1β in human corneal fibroblasts. Immunopharmacol Immunotoxicol. 2014 Oct;36(5):371-7. PMID: 25151996.

Ilhan S, Yılmaz N, Nacar E, et al. The effect of caffeic acid phenethyl ester on isoproterenol-induced myocardial injury in hypertensive rats. Anadolu Kardiyol Derg. 2014 Jun 3. [Epub ahead of print]. PMID: 25036319.

Chiang EP, Tsai SY, Kuo YH, et al. Caffeic acid derivatives inhibit the growth of colon cancer: involvement of the PI3-K/Akt and AMPK signaling pathways. PLoS One. 2014 Jun 24;9(6):e99631. PMID: 24960186.

Shin SH, Seo SG, Min S, et al. Caffeic acid phenethyl ester, a major component of propolis, suppresses high fat diet-induced obesity through inhibiting adipogenesis at the mitotic clonal expansion stage. J Agric Food Chem. 2014 May 14;62(19):4306-12. PMID: 24611533.

Hassan NA, El-Bassossy HM, Mahmoud MF, et al. Caffeic acid phenethyl ester, a 5-lipoxygenase enzyme inhibitor, alleviates diabetic atherosclerotic manifestations: effect on vascular reactivity and stiffness. Chem Biol Interact. 2014 Apr 25;213:28-36. PMID: 24508943.

" Xi Not dangerous goods.

LKT P3597 Pizotyline Malate 1 g 94.4 5-HT1A partial agonist, 5-HT2C antagonist. 4-(9,10-Dihydro-4H-benzo[4,5]cyclohepta[1,2-b]thien-4ylidene)-1-methylpiperidine Pizotifen; Pizotifan; BC105 5189-11-7 ≥98% 429.54 C19H21NS C4H6O5 CN1CCC(=C2C3=C(CCC4=CC=CC=C42)SC=C3)CC1.C(C(C(=O)O)O)C(=O)O Protect from light. Ambient Ambient Very slightly soluble in water. Slightly soluble in chloroform and ethanol. "Young R, Khorana N, Bondareva T, et al. Pizotyline effectively attenuates the stimulus effects of N-methyl-3,4-methylenedioxyamphetamine (MDMA). Pharmacol Biochem Behav. 2005 Oct;82(2):404-10. PMID: 16253319.

Strachan AT, Leiper JB, Maughan RJ. Serotonin2C receptor blockade and thermoregulation during exercise in the heat. Med Sci Sports Exerc. 2005 Mar;37(3):389-94. PMID: 15741836.

Newman-Tancredi A, Conte C, Chaput C, et al. Agonist activity of antimigraine drugs at recombinant human 5-HT1A receptors: potential implications for prophylactic and acute therapy. Naunyn Schmiedebergs Arch Pharmacol. 1997 Jun;355(6):682-8. PMID: 9205951.

" Not dangerous goods.

LKT P3597 Pizotyline Malate 5 g 346.5 5-HT1A partial agonist, 5-HT2C antagonist. 4-(9,10-Dihydro-4H-benzo[4,5]cyclohepta[1,2-b]thien-4ylidene)-1-methylpiperidine Pizotifen; Pizotifan; BC105 5189-11-7 ≥98% 429.54 C19H21NS C4H6O5 CN1CCC(=C2C3=C(CCC4=CC=CC=C42)SC=C3)CC1.C(C(C(=O)O)O)C(=O)O Protect from light. Ambient Ambient Very slightly soluble in water. Slightly soluble in chloroform and ethanol. "Young R, Khorana N, Bondareva T, et al. Pizotyline effectively attenuates the stimulus effects of N-methyl-3,4-methylenedioxyamphetamine (MDMA). Pharmacol Biochem Behav. 2005 Oct;82(2):404-10. PMID: 16253319.

Strachan AT, Leiper JB, Maughan RJ. Serotonin2C receptor blockade and thermoregulation during exercise in the heat. Med Sci Sports Exerc. 2005 Mar;37(3):389-94. PMID: 15741836.

Newman-Tancredi A, Conte C, Chaput C, et al. Agonist activity of antimigraine drugs at recombinant human 5-HT1A receptors: potential implications for prophylactic and acute therapy. Naunyn Schmiedebergs Arch Pharmacol. 1997 Jun;355(6):682-8. PMID: 9205951.

" Not dangerous goods.

LKT P3597 Pizotyline Malate 10 g 587.9 5-HT1A partial agonist, 5-HT2C antagonist. 4-(9,10-Dihydro-4H-benzo[4,5]cyclohepta[1,2-b]thien-4ylidene)-1-methylpiperidine Pizotifen; Pizotifan; BC105 5189-11-7 ≥98% 429.54 C19H21NS C4H6O5 CN1CCC(=C2C3=C(CCC4=CC=CC=C42)SC=C3)CC1.C(C(C(=O)O)O)C(=O)O Protect from light. Ambient Ambient Very slightly soluble in water. Slightly soluble in chloroform and ethanol. "Young R, Khorana N, Bondareva T, et al. Pizotyline effectively attenuates the stimulus effects of N-methyl-3,4-methylenedioxyamphetamine (MDMA). Pharmacol Biochem Behav. 2005 Oct;82(2):404-10. PMID: 16253319.

Strachan AT, Leiper JB, Maughan RJ. Serotonin2C receptor blockade and thermoregulation during exercise in the heat. Med Sci Sports Exerc. 2005 Mar;37(3):389-94. PMID: 15741836.

Newman-Tancredi A, Conte C, Chaput C, et al. Agonist activity of antimigraine drugs at recombinant human 5-HT1A receptors: potential implications for prophylactic and acute therapy. Naunyn Schmiedebergs Arch Pharmacol. 1997 Jun;355(6):682-8. PMID: 9205951.

" Not dangerous goods.

LKT P3576 Pitavastatin Calcium 10 mg 67.9 Statin; HMG-CoA reductase inhibitor. 147526-32-7 ≥98% 880.98 C50H46F2N2O8Ca C1CC1C2=NC3=CC=CC=C3C(=C2C=CC(CC(CC(=O)[O-])O)O)C4=CC=C(C=C4)F.C1CC1C2=NC3=CC=CC=C3C(=C2C=CC(CC(CC(=O)[O-])O)O)C4=CC=C(C=C4)F.[Ca+2] Ambient Ambient DMSO to 51 mg/mL. "Tajiri K, Shimojo N, Sakai S, et al. Pitavastatin regulates helper T-cell differentiation and ameliorates autoimmune myocarditis in mice. Cardiovasc Drugs Ther. 2013 Oct;27(5):413-24. PMID: 23722419.

Ansari JA, Bhandari U, Haque SE, et al. Enhancement of antioxidant defense mechanism by pitavastatin and rosuvastatin on obesity-induced oxidative stress in Wistar rats. Toxicol Mech Methods. 2012 Jan;22(1):67-73. PMID: 21859367.

Abd El-Latif MI, Murota H, Terao M, et al. Effects of a 3-hydroxy-3-methylglutaryl coenzyme A reductase inhibitor and low-density lipoprotein on proliferation and migration of keratinocytes. Br J Dermatol. 2010 Jul;163(1):128-37. PMID: 20163419.

Suzuki J, Koga N, Kosuge H, et al. Pitavastatin suppresses acute and chronic rejection in murine cardiac allografts. Transplantation. 2007 Apr 27;83(8):1093-7. PMID: 17452900.

Aoki T, Yamazaki H, Suzuki H, et al. Cholesterol-lowering effect of NK-104, a 3-hydroxy-3-methylglutaryl-coenzyme A reductase inhibitor, in guinea pig model of hyperlipidemia. Arzneimittelforschung. 2001;51(3):197-203. PMID: 11304935.

" Not dangerous goods.

LKT P3576 Pitavastatin Calcium 25 mg 108.8 Statin; HMG-CoA reductase inhibitor. 147526-32-7 ≥98% 880.98 C50H46F2N2O8Ca C1CC1C2=NC3=CC=CC=C3C(=C2C=CC(CC(CC(=O)[O-])O)O)C4=CC=C(C=C4)F.C1CC1C2=NC3=CC=CC=C3C(=C2C=CC(CC(CC(=O)[O-])O)O)C4=CC=C(C=C4)F.[Ca+2] Ambient Ambient DMSO to 51 mg/mL. "Tajiri K, Shimojo N, Sakai S, et al. Pitavastatin regulates helper T-cell differentiation and ameliorates autoimmune myocarditis in mice. Cardiovasc Drugs Ther. 2013 Oct;27(5):413-24. PMID: 23722419.

Ansari JA, Bhandari U, Haque SE, et al. Enhancement of antioxidant defense mechanism by pitavastatin and rosuvastatin on obesity-induced oxidative stress in Wistar rats. Toxicol Mech Methods. 2012 Jan;22(1):67-73. PMID: 21859367.

Abd El-Latif MI, Murota H, Terao M, et al. Effects of a 3-hydroxy-3-methylglutaryl coenzyme A reductase inhibitor and low-density lipoprotein on proliferation and migration of keratinocytes. Br J Dermatol. 2010 Jul;163(1):128-37. PMID: 20163419.

Suzuki J, Koga N, Kosuge H, et al. Pitavastatin suppresses acute and chronic rejection in murine cardiac allografts. Transplantation. 2007 Apr 27;83(8):1093-7. PMID: 17452900.

Aoki T, Yamazaki H, Suzuki H, et al. Cholesterol-lowering effect of NK-104, a 3-hydroxy-3-methylglutaryl-coenzyme A reductase inhibitor, in guinea pig model of hyperlipidemia. Arzneimittelforschung. 2001;51(3):197-203. PMID: 11304935.

" Not dangerous goods.

LKT P3576 Pitavastatin Calcium 100 mg 285.4 Statin; HMG-CoA reductase inhibitor. 147526-32-7 ≥98% 880.98 C50H46F2N2O8Ca C1CC1C2=NC3=CC=CC=C3C(=C2C=CC(CC(CC(=O)[O-])O)O)C4=CC=C(C=C4)F.C1CC1C2=NC3=CC=CC=C3C(=C2C=CC(CC(CC(=O)[O-])O)O)C4=CC=C(C=C4)F.[Ca+2] Ambient Ambient DMSO to 51 mg/mL. "Tajiri K, Shimojo N, Sakai S, et al. Pitavastatin regulates helper T-cell differentiation and ameliorates autoimmune myocarditis in mice. Cardiovasc Drugs Ther. 2013 Oct;27(5):413-24. PMID: 23722419.

Ansari JA, Bhandari U, Haque SE, et al. Enhancement of antioxidant defense mechanism by pitavastatin and rosuvastatin on obesity-induced oxidative stress in Wistar rats. Toxicol Mech Methods. 2012 Jan;22(1):67-73. PMID: 21859367.

Abd El-Latif MI, Murota H, Terao M, et al. Effects of a 3-hydroxy-3-methylglutaryl coenzyme A reductase inhibitor and low-density lipoprotein on proliferation and migration of keratinocytes. Br J Dermatol. 2010 Jul;163(1):128-37. PMID: 20163419.

Suzuki J, Koga N, Kosuge H, et al. Pitavastatin suppresses acute and chronic rejection in murine cardiac allografts. Transplantation. 2007 Apr 27;83(8):1093-7. PMID: 17452900.

Aoki T, Yamazaki H, Suzuki H, et al. Cholesterol-lowering effect of NK-104, a 3-hydroxy-3-methylglutaryl-coenzyme A reductase inhibitor, in guinea pig model of hyperlipidemia. Arzneimittelforschung. 2001;51(3):197-203. PMID: 11304935.

" Not dangerous goods.

LKT P2410 Phenethyl Dimethyl Caffeate 50 mg 78.6 Caffeic acid derivative. Caffeic Acid, Dimethyl Phenethyl Ester 14551-14-0 ≥98% 312.37 C19H20O4 COC1=C(C=C(C=C1)C=CC(=O)OCCC2=CC=CC=C2)OC Ambient Ambient Soluble in DMSO. "Ho CC, Lin SS, Chou MY, et al. Effects of CAPE-like compounds on HIV replication in vitro and modulation of cytokines in vivo. J Antimicrob Chemother. 2005 Aug;56(2):372-9. PMID: 16002419.

Lee YJ, Liao PH, Chen WK, et al. Preferential cytotoxicity of caffeic acid phenethyl ester analogues on oral cancer cells. Cancer Lett. 2000 May 29;153(1-2):51-6. PMID: 10779629.

" Not dangerous goods.

LKT P2410 Phenethyl Dimethyl Caffeate 100 mg 114.6 Caffeic acid derivative. Caffeic Acid, Dimethyl Phenethyl Ester 14551-14-0 ≥98% 312.37 C19H20O4 COC1=C(C=C(C=C1)C=CC(=O)OCCC2=CC=CC=C2)OC Ambient Ambient Soluble in DMSO. "Ho CC, Lin SS, Chou MY, et al. Effects of CAPE-like compounds on HIV replication in vitro and modulation of cytokines in vivo. J Antimicrob Chemother. 2005 Aug;56(2):372-9. PMID: 16002419.

Lee YJ, Liao PH, Chen WK, et al. Preferential cytotoxicity of caffeic acid phenethyl ester analogues on oral cancer cells. Cancer Lett. 2000 May 29;153(1-2):51-6. PMID: 10779629.

" Not dangerous goods.

LKT P2410 Phenethyl Dimethyl Caffeate 500 mg 375.6 Caffeic acid derivative. Caffeic Acid, Dimethyl Phenethyl Ester 14551-14-0 ≥98% 312.37 C19H20O4 COC1=C(C=C(C=C1)C=CC(=O)OCCC2=CC=CC=C2)OC Ambient Ambient Soluble in DMSO. "Ho CC, Lin SS, Chou MY, et al. Effects of CAPE-like compounds on HIV replication in vitro and modulation of cytokines in vivo. J Antimicrob Chemother. 2005 Aug;56(2):372-9. PMID: 16002419.

Lee YJ, Liao PH, Chen WK, et al. Preferential cytotoxicity of caffeic acid phenethyl ester analogues on oral cancer cells. Cancer Lett. 2000 May 29;153(1-2):51-6. PMID: 10779629.

" Not dangerous goods.

LKT P2445 GLa Peptide 1 mg 390.2 Antimicrobial peptide found in amphibians. "L-Leucinamide, glycyl-L-methionyl-L-alanyl-L-seryl-L-lysyl-

L-alanylglylcyl-L-alanyl-L-isoleucyl-L-alanylglycyl-L-lysyl-

L-isoleucyl-L-alanyl-L-lysyl-L-valyl-L-alanyl-L-leucyl-L-

lysyl-L-alanyl-" Gla peptide; Pgl(a); PGLa 102068-15-5 ≥98% 1968.5 C88H162N26O22S CCC(C)C(C(=O)NC(C)C(=O)NCC(=O)NC(CCCCN)C(=O)NC(C(C)CC)C(=O)NC(C)C(=O)NC(CCCCN)C(=O)NC(C(C)C)C(=O)NC(C)C(=O)NC(CC(C)C)C(=O)NC(CCCCN)C(=O)NC(C)C(=O)NC(CC(C)C)C(=O)N)NC(=O)C(C)NC(=O)CNC(=O)C(C)NC(=O)C(CCCCN)NC(=O)C(CO)NC(=O)C(C)NC(=O)C(CCSC)NC(=O)CN Ambient -20°C Kuchler K, Kreil G, Sures I. The genes for the frog skin peptides GLa, xenopsin, levitide and caerulein contain a homologous export exon encoding a signal sequence and part of an amphiphilic peptide. Eur J Biochem. 1989 Feb 1;179(2):281-5. PMID: 2465151. Not dangerous goods.

LKT P2502 Phenethyl Glucosinolate Potassium 5 mg 218.4 Found in cruciferous vegetables. "Glucopyranose, 1-thio-, 1-hydrocinnamohydroximate NO-

(hydrogen sulfate), beta-D-" Gluconasturtiin 18425-76-8 ≥97% 461.55 C15H20NO9S2K Ambient -20°C Soluble in water. "Gupta P, Wright SE, Kim SH, et al. Phenethyl isothiocyanate: A comprehensive review of anti-cancer mechanisms. Biochim Biophys Acta. 2014 Aug 23;1846(2):405-424. PMID: 25152445.

Natella F, Maldini M, Leoni G, et al. Glucosinolates redox activities: can they act as antioxidants? Food Chem. 2014 Apr 15;149:226-32. PMID: 24295700.

" Not dangerous goods.

LKT P2502 Phenethyl Glucosinolate Potassium 10 mg 394.4 Found in cruciferous vegetables. "Glucopyranose, 1-thio-, 1-hydrocinnamohydroximate NO-

(hydrogen sulfate), beta-D-" Gluconasturtiin 18425-76-8 ≥97% 461.55 C15H20NO9S2K Ambient -20°C Soluble in water. "Gupta P, Wright SE, Kim SH, et al. Phenethyl isothiocyanate: A comprehensive review of anti-cancer mechanisms. Biochim Biophys Acta. 2014 Aug 23;1846(2):405-424. PMID: 25152445.

Natella F, Maldini M, Leoni G, et al. Glucosinolates redox activities: can they act as antioxidants? Food Chem. 2014 Apr 15;149:226-32. PMID: 24295700.

" Not dangerous goods.

LKT P2502 Phenethyl Glucosinolate Potassium 100 mg 2341.5 Found in cruciferous vegetables. "Glucopyranose, 1-thio-, 1-hydrocinnamohydroximate NO-

(hydrogen sulfate), beta-D-" Gluconasturtiin 18425-76-8 ≥97% 461.55 C15H20NO9S2K Ambient -20°C Soluble in water. "Gupta P, Wright SE, Kim SH, et al. Phenethyl isothiocyanate: A comprehensive review of anti-cancer mechanisms. Biochim Biophys Acta. 2014 Aug 23;1846(2):405-424. PMID: 25152445.

Natella F, Maldini M, Leoni G, et al. Glucosinolates redox activities: can they act as antioxidants? Food Chem. 2014 Apr 15;149:226-32. PMID: 24295700.

" Not dangerous goods.

LKT P2510 4-Phenylbutylisothiocyanate 1 g 61.1 Synthetic ITC. 4-isothiocyanatobutylbenzene "

" 61499-10-3 ≥98% 191.31 C11H13NS C1=CC=C(C=C1)CCCCN=C=S Ambient -20°C Soluble in DMSO. "Son HY, Nishikawa A, Furukawa F, et al. Modifying effects of 4-phenylbutyl isothiocyanate on N-nitrosobis(2-oxopropyl)amine-induced tumorigenesis in hamsters. Cancer Lett. 2000 Nov 28;160(2):141-7. PMID: 11053643.

Yu R, Mandlekar S, Harvey KJ, et al. Chemopreventive isothiocyanates induce apoptosis and caspase-3-like protease activity. Cancer Res. 1998 Feb 1;58(3):402-8. PMID: 9458080.

Guo Z, Smith TJ, Wang E, et al. Structure-activity relationships of arylalkyl isothiocyanates for the inhibition of 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone metabolism and the modulation of xenobiotic-metabolizing enzymes in rats and mice. Carcinogenesis. 1993 Jun;14(6):1167-73. PMID: 8508504.

" Xn, C "UN number: 2922     Class: 8 (6.1)     Packing Group: III

Proper shipping name: Corrosive liquid, toxic, n.o.s. (4-Phenylbutylisothiocyanate)"

LKT P2510 4-Phenylbutylisothiocyanate 5 g 237.8 Synthetic ITC. 4-isothiocyanatobutylbenzene "

" 61499-10-3 ≥98% 191.31 C11H13NS C1=CC=C(C=C1)CCCCN=C=S Ambient -20°C Soluble in DMSO. "Son HY, Nishikawa A, Furukawa F, et al. Modifying effects of 4-phenylbutyl isothiocyanate on N-nitrosobis(2-oxopropyl)amine-induced tumorigenesis in hamsters. Cancer Lett. 2000 Nov 28;160(2):141-7. PMID: 11053643.

Yu R, Mandlekar S, Harvey KJ, et al. Chemopreventive isothiocyanates induce apoptosis and caspase-3-like protease activity. Cancer Res. 1998 Feb 1;58(3):402-8. PMID: 9458080.

Guo Z, Smith TJ, Wang E, et al. Structure-activity relationships of arylalkyl isothiocyanates for the inhibition of 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone metabolism and the modulation of xenobiotic-metabolizing enzymes in rats and mice. Carcinogenesis. 1993 Jun;14(6):1167-73. PMID: 8508504.

" Xn, C "UN number: 2922     Class: 8 (6.1)     Packing Group: III

Proper shipping name: Corrosive liquid, toxic, n.o.s. (4-Phenylbutylisothiocyanate)"

LKT P2510 4-Phenylbutylisothiocyanate 10 g 434.9 Synthetic ITC. 4-isothiocyanatobutylbenzene "

" 61499-10-3 ≥98% 191.31 C11H13NS C1=CC=C(C=C1)CCCCN=C=S Ambient -20°C Soluble in DMSO. "Son HY, Nishikawa A, Furukawa F, et al. Modifying effects of 4-phenylbutyl isothiocyanate on N-nitrosobis(2-oxopropyl)amine-induced tumorigenesis in hamsters. Cancer Lett. 2000 Nov 28;160(2):141-7. PMID: 11053643.

Yu R, Mandlekar S, Harvey KJ, et al. Chemopreventive isothiocyanates induce apoptosis and caspase-3-like protease activity. Cancer Res. 1998 Feb 1;58(3):402-8. PMID: 9458080.

Guo Z, Smith TJ, Wang E, et al. Structure-activity relationships of arylalkyl isothiocyanates for the inhibition of 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone metabolism and the modulation of xenobiotic-metabolizing enzymes in rats and mice. Carcinogenesis. 1993 Jun;14(6):1167-73. PMID: 8508504.

" Xn, C "UN number: 2922     Class: 8 (6.1)     Packing Group: III

Proper shipping name: Corrosive liquid, toxic, n.o.s. (4-Phenylbutylisothiocyanate)"

LKT P3568 Pirarubicin 5 mg 82.4 Anthracycline, DNA intercalator; topoisomerase II and DNA polymerase inhibitor. (7S,9S)-7-[(2R,4S,5S,6S)-4-amino-6-methyl-5-[(2S)-oxan-2-yl]oxyoxan-2-yl]oxy-6,9,11-trihydroxy-9-(2-hydroxyacetyl)-4-methoxy-8,10-dihydro-7H-tetracene-5,12-dione THP 72496-41-4 ≥90% 627.64 C32H37NO12 CC1C(C(CC(O1)OC2CC(CC3=C(C4=C(C(=C23)O)C(=O)C5=C(C4=O)C=CC=C5OC)O)(C(=O)CO)O)N)OC6CCCCO6 Ambient Ambient "Hiyama E, Ueda Y, Onitake Y, et al. A cisplatin plus pirarubicin-based JPLT2 chemotherapy for hepatoblastoma: experience and future of the Japanese Study Group for Pediatric Liver Tumor (JPLT). Pediatr Surg Int. 2013 Oct;29(10):1071-5. PMID: 24026876.

Kataoka K, Naomoto Y, Muro M, et al. Antitumor effect of pirarubicin (THP) against human colon cancer transplanted into nude mice and the mechanism of cell cycle progression. Gan To Kagaku Ryoho. 1992 Mar;19(3):367-71. PMID: 1543363.

Hirano S, Agata N, Hara Y, et al. Pirarubicin-induced endothelium-dependent relaxation in rat isolated aorta. J Pharm Pharmacol. 1991 Dec;43(12):848-54. PMID: 1687584.

Schott B, Robert J. Comparative cytotoxicity, DNA synthesis inhibition and drug incorporation of eight anthracyclines in a model of doxorubicin-sensitive and -resistant rat glioblastoma cells. Biochem Pharmacol. 1989 Jan 1;38(1):167-72. PMID: 2910297.

Tanaka M, Yoshida S, Kimura K. Mechanism of inhibition of DNA polymerases by 4'-epiadriamycin and 4'-O-tetrahydropyranyladriamycin. Gann. 1983 Dec;74(6):829-36. PMID: 6365674.

" Not dangerous goods.

LKT P3568 Pirarubicin 10 mg 120.1 Anthracycline, DNA intercalator; topoisomerase II and DNA polymerase inhibitor. (7S,9S)-7-[(2R,4S,5S,6S)-4-amino-6-methyl-5-[(2S)-oxan-2-yl]oxyoxan-2-yl]oxy-6,9,11-trihydroxy-9-(2-hydroxyacetyl)-4-methoxy-8,10-dihydro-7H-tetracene-5,12-dione THP 72496-41-4 ≥90% 627.64 C32H37NO12 CC1C(C(CC(O1)OC2CC(CC3=C(C4=C(C(=C23)O)C(=O)C5=C(C4=O)C=CC=C5OC)O)(C(=O)CO)O)N)OC6CCCCO6 Ambient Ambient "Hiyama E, Ueda Y, Onitake Y, et al. A cisplatin plus pirarubicin-based JPLT2 chemotherapy for hepatoblastoma: experience and future of the Japanese Study Group for Pediatric Liver Tumor (JPLT). Pediatr Surg Int. 2013 Oct;29(10):1071-5. PMID: 24026876.

Kataoka K, Naomoto Y, Muro M, et al. Antitumor effect of pirarubicin (THP) against human colon cancer transplanted into nude mice and the mechanism of cell cycle progression. Gan To Kagaku Ryoho. 1992 Mar;19(3):367-71. PMID: 1543363.

Hirano S, Agata N, Hara Y, et al. Pirarubicin-induced endothelium-dependent relaxation in rat isolated aorta. J Pharm Pharmacol. 1991 Dec;43(12):848-54. PMID: 1687584.

Schott B, Robert J. Comparative cytotoxicity, DNA synthesis inhibition and drug incorporation of eight anthracyclines in a model of doxorubicin-sensitive and -resistant rat glioblastoma cells. Biochem Pharmacol. 1989 Jan 1;38(1):167-72. PMID: 2910297.

Tanaka M, Yoshida S, Kimura K. Mechanism of inhibition of DNA polymerases by 4'-epiadriamycin and 4'-O-tetrahydropyranyladriamycin. Gann. 1983 Dec;74(6):829-36. PMID: 6365674.

" Not dangerous goods.

LKT P3568 Pirarubicin 25 mg 434.4 Anthracycline, DNA intercalator; topoisomerase II and DNA polymerase inhibitor. (7S,9S)-7-[(2R,4S,5S,6S)-4-amino-6-methyl-5-[(2S)-oxan-2-yl]oxyoxan-2-yl]oxy-6,9,11-trihydroxy-9-(2-hydroxyacetyl)-4-methoxy-8,10-dihydro-7H-tetracene-5,12-dione THP 72496-41-4 ≥90% 627.64 C32H37NO12 CC1C(C(CC(O1)OC2CC(CC3=C(C4=C(C(=C23)O)C(=O)C5=C(C4=O)C=CC=C5OC)O)(C(=O)CO)O)N)OC6CCCCO6 Ambient Ambient "Hiyama E, Ueda Y, Onitake Y, et al. A cisplatin plus pirarubicin-based JPLT2 chemotherapy for hepatoblastoma: experience and future of the Japanese Study Group for Pediatric Liver Tumor (JPLT). Pediatr Surg Int. 2013 Oct;29(10):1071-5. PMID: 24026876.

Kataoka K, Naomoto Y, Muro M, et al. Antitumor effect of pirarubicin (THP) against human colon cancer transplanted into nude mice and the mechanism of cell cycle progression. Gan To Kagaku Ryoho. 1992 Mar;19(3):367-71. PMID: 1543363.

Hirano S, Agata N, Hara Y, et al. Pirarubicin-induced endothelium-dependent relaxation in rat isolated aorta. J Pharm Pharmacol. 1991 Dec;43(12):848-54. PMID: 1687584.

Schott B, Robert J. Comparative cytotoxicity, DNA synthesis inhibition and drug incorporation of eight anthracyclines in a model of doxorubicin-sensitive and -resistant rat glioblastoma cells. Biochem Pharmacol. 1989 Jan 1;38(1):167-72. PMID: 2910297.

Tanaka M, Yoshida S, Kimura K. Mechanism of inhibition of DNA polymerases by 4'-epiadriamycin and 4'-O-tetrahydropyranyladriamycin. Gann. 1983 Dec;74(6):829-36. PMID: 6365674.

" Not dangerous goods.

LKT P2513 Phenyl Isothiocyanate 50 g 44.9 ITC found in cruciferous vegetables. Isothiocyanato benzene PITC; Isothiocyanatobenzene; Phenyl mustard oil; Thiocarbanil 103-72-0 ≥98% 135.19 C7H5NS C1=CC=C(C=C1)N=C=S Ambient 4°C Insoluble in water. "Abreu AC, Borges A, Simões LC, et al. Antibacterial activity of phenyl isothiocyanate on Escherichia coli and Staphylococcus aureus. Med Chem. 2013 Aug;9(5):756-61. PMID: 22974327.

Thejass P, Kuttan G. Inhibition of endothelial cell differentiation and proinflammatory cytokine production during angiogenesis by allyl isothiocyanate and phenyl isothiocyanate. Integr Cancer Ther. 2007 Dec;6(4):389-99. PMID: 18048887.

Manesh C, Kuttan G. Anti-tumour and anti-oxidant activity of naturally occurring isothiocyanates. J Exp Clin Cancer Res. 2003 Jun;22(2):193-9. PMID: 12866569.

" C, Repr., T "UN number: 2927     Class: 6.1 (8)     Packing Group: II

Proper shipping name: Toxic liquid, corrosive, organic, n.o.s. (Phenyl isothiocyanate)

Marine pollutant: No     Poison Inhalation Hazard: No"

LKT P2513 Phenyl Isothiocyanate 100 g 67.2 ITC found in cruciferous vegetables. Isothiocyanato benzene PITC; Isothiocyanatobenzene; Phenyl mustard oil; Thiocarbanil 103-72-0 ≥98% 135.19 C7H5NS C1=CC=C(C=C1)N=C=S Ambient 4°C Insoluble in water. "Abreu AC, Borges A, Simões LC, et al. Antibacterial activity of phenyl isothiocyanate on Escherichia coli and Staphylococcus aureus. Med Chem. 2013 Aug;9(5):756-61. PMID: 22974327.

Thejass P, Kuttan G. Inhibition of endothelial cell differentiation and proinflammatory cytokine production during angiogenesis by allyl isothiocyanate and phenyl isothiocyanate. Integr Cancer Ther. 2007 Dec;6(4):389-99. PMID: 18048887.

Manesh C, Kuttan G. Anti-tumour and anti-oxidant activity of naturally occurring isothiocyanates. J Exp Clin Cancer Res. 2003 Jun;22(2):193-9. PMID: 12866569.

" C, Repr., T "UN number: 2927     Class: 6.1 (8)     Packing Group: II

Proper shipping name: Toxic liquid, corrosive, organic, n.o.s. (Phenyl isothiocyanate)

Marine pollutant: No     Poison Inhalation Hazard: No"

LKT P2515 3-Phenylpropyl Isothiocyanate 5 g 230.8 Synthetic ITC. 3-isothiocyanatopropylbenzene Phenylpropyl isothiocyanate 2627-27-2 ≥98% 177.27 C10H11NS C1=CC=C(C=C1)CCCN=C=S Ambient 4°C Soluble in DMSO. "Tayem Y, Green CJ, Motterlini R, et al. Isothiocyanate-cysteine conjugates protect renal tissue against cisplatin-induced apoptosis via induction of heme oxygenase-1. Pharmacol Res. 2014 Mar;81:1-9. PMID: 24434421.

Hecht SS, Upadhyaya P, Wang M, et al. Inhibition of lung tumorigenesis in A/J mice by N-acetyl-S-(N-2-phenethylthiocarbamoyl)-L-cysteine and myo-inositol, individually and in combination. Carcinogenesis. 2002 Sep;23(9):1455-61. PMID: 12189187.

" Xn, C "UN number: 2922     Class:  8     Packing group:  III

Proper shipping name:  CORROSIVE LIQUID, TOXIC, C.O.S. (3-Phenylpropyl isothiocyante)"

LKT P2515 3-Phenylpropyl Isothiocyanate 10 g 413.1 Synthetic ITC. 3-isothiocyanatopropylbenzene Phenylpropyl isothiocyanate 2627-27-2 ≥98% 177.27 C10H11NS C1=CC=C(C=C1)CCCN=C=S Ambient 4°C Soluble in DMSO. "Tayem Y, Green CJ, Motterlini R, et al. Isothiocyanate-cysteine conjugates protect renal tissue against cisplatin-induced apoptosis via induction of heme oxygenase-1. Pharmacol Res. 2014 Mar;81:1-9. PMID: 24434421.

Hecht SS, Upadhyaya P, Wang M, et al. Inhibition of lung tumorigenesis in A/J mice by N-acetyl-S-(N-2-phenethylthiocarbamoyl)-L-cysteine and myo-inositol, individually and in combination. Carcinogenesis. 2002 Sep;23(9):1455-61. PMID: 12189187.

" Xn, C "UN number: 2922     Class:  8     Packing group:  III

Proper shipping name:  CORROSIVE LIQUID, TOXIC, C.O.S. (3-Phenylpropyl isothiocyante)"

LKT P3465 Piperine 1 g 27.2 Alkaloid found in black and long peppers; TRPV1 agonist. 1-[(2E,4E)-5-(1,3-Benzodioxol-5-yl)-1-oxo-2,4-pentadienyl]piperidine (E,E)-1-Piperoylpiperidine 94-62-2 ≥95% 285.34 C17H19NO3 C1CCN(CC1)C(=O)C=CC=CC2=CC3=C(C=C2)OCO3 Protect from light and heat. Ambient Ambient Soluble in alcohol, chloroform, ether, benzene or acetic acid. "Ouyang DY, Zeng LH, Pan H, et al. Piperine inhibits the proliferation of human prostate cancer cells via induction of cell cycle arrest and autophagy. Food Chem Toxicol. 2013 Oct;60:424-30. PMID: 23939040.

Kumar S, Sharma S, Vasudeva N. Screening of antidiabetic and antihyperlipidemic potential of oil from Piper longum and piperine with their possible mechanism. Expert Opin Pharmacother. 2013 Sep;14(13):1723-36. PMID: 23875561.

Shrivastava P, Vaibhav K, Tabassum R, et al. Anti-apoptotic and anti-inflammatory effect of Piperine on 6-OHDA induced Parkinson's rat model. J Nutr Biochem. 2013 Apr;24(4):680-7. PMID: 22819561.

Bae GS, Kim JJ, Park KC, et al. Piperine inhibits lipopolysaccharide-induced maturation of bone-marrow-derived dendritic cells through inhibition of ERK and JNK activation. Phytother Res. 2012 Dec;26(12):1893-7. PMID: 22430952.

Chonpathompikunlert P, Wattanathorn J, Muchimapura S. Piperine, the main alkaloid of Thai black pepper, protects against neurodegeneration and cognitive impairment in animal model of cognitive deficit like condition of Alzheimer's disease. Food Chem Toxicol. 2010 Mar;48(3):798-802. PMID: 20034530.

Fofaria NM, Kim SH, Srivastava SK. Piperine causes G1 phase cell cycle arrest and apoptosis in melanoma cells through checkpoint kinase-1 activation. PLoS One. 2014 May 7;9(5):e94298. PMID: 24804719.

" Xn Not dangerous goods.

LKT P2810 Phenylbutazone 25 g 41.4 NSAID; COX-1/2 inhibitor. 4-Butyl-1,2-diphenyl-3,5-pyrazolidinedione Ambene; Artrizin; Butadion; Butoz; Equipalazone; Fenibutol; Intrabutazone; Phenyzene; Tevcodyne; Uzone 50-33-9 ≥98% 308.37 C19H20N2O2 CCCCC1C(=O)N(N(C1=O)C2=CC=CC=C2)C3=CC=CC=C3 Ambient Ambient Soluble in water. "Cusan C, Altinier G, Sosa S, et al. Anti-inflammatory and anti-oxidant activity of a new class of phenyl-pyrazolone derivatives. Curr Drug Discov Technol. 2006 Mar;3(1):67-73. PMID: 16712464.

Kettle AJ, Winterbourn CC. Mechanism of inhibition of myeloperoxidase by anti-inflammatory drugs. Biochem Pharmacol. 1991 May 15;41(10):1485-92. PMID: 1850278.

" Carc., Xi, Xn "UN number: 2811     Class: 6.1     Packing Group: III

Proper shipping name: Toxic solid, organic, n.o.s. (Phenylbutazone)"

LKT P3465 Piperine 5 g 40.7 Alkaloid found in black and long peppers; TRPV1 agonist. 1-[(2E,4E)-5-(1,3-Benzodioxol-5-yl)-1-oxo-2,4-pentadienyl]piperidine (E,E)-1-Piperoylpiperidine 94-62-2 ≥95% 285.34 C17H19NO3 C1CCN(CC1)C(=O)C=CC=CC2=CC3=C(C=C2)OCO3 Protect from light and heat. Ambient Ambient Soluble in alcohol, chloroform, ether, benzene or acetic acid. "Ouyang DY, Zeng LH, Pan H, et al. Piperine inhibits the proliferation of human prostate cancer cells via induction of cell cycle arrest and autophagy. Food Chem Toxicol. 2013 Oct;60:424-30. PMID: 23939040.

Kumar S, Sharma S, Vasudeva N. Screening of antidiabetic and antihyperlipidemic potential of oil from Piper longum and piperine with their possible mechanism. Expert Opin Pharmacother. 2013 Sep;14(13):1723-36. PMID: 23875561.

Shrivastava P, Vaibhav K, Tabassum R, et al. Anti-apoptotic and anti-inflammatory effect of Piperine on 6-OHDA induced Parkinson's rat model. J Nutr Biochem. 2013 Apr;24(4):680-7. PMID: 22819561.

Bae GS, Kim JJ, Park KC, et al. Piperine inhibits lipopolysaccharide-induced maturation of bone-marrow-derived dendritic cells through inhibition of ERK and JNK activation. Phytother Res. 2012 Dec;26(12):1893-7. PMID: 22430952.

Chonpathompikunlert P, Wattanathorn J, Muchimapura S. Piperine, the main alkaloid of Thai black pepper, protects against neurodegeneration and cognitive impairment in animal model of cognitive deficit like condition of Alzheimer's disease. Food Chem Toxicol. 2010 Mar;48(3):798-802. PMID: 20034530.

Fofaria NM, Kim SH, Srivastava SK. Piperine causes G1 phase cell cycle arrest and apoptosis in melanoma cells through checkpoint kinase-1 activation. PLoS One. 2014 May 7;9(5):e94298. PMID: 24804719.

" Xn Not dangerous goods.

LKT P2810 Phenylbutazone 100 g 109.9 NSAID; COX-1/2 inhibitor. 4-Butyl-1,2-diphenyl-3,5-pyrazolidinedione Ambene; Artrizin; Butadion; Butoz; Equipalazone; Fenibutol; Intrabutazone; Phenyzene; Tevcodyne; Uzone 50-33-9 ≥98% 308.37 C19H20N2O2 CCCCC1C(=O)N(N(C1=O)C2=CC=CC=C2)C3=CC=CC=C3 Ambient Ambient Soluble in water. "Cusan C, Altinier G, Sosa S, et al. Anti-inflammatory and anti-oxidant activity of a new class of phenyl-pyrazolone derivatives. Curr Drug Discov Technol. 2006 Mar;3(1):67-73. PMID: 16712464.

Kettle AJ, Winterbourn CC. Mechanism of inhibition of myeloperoxidase by anti-inflammatory drugs. Biochem Pharmacol. 1991 May 15;41(10):1485-92. PMID: 1850278.

" Carc., Xi, Xn "UN number: 2811     Class: 6.1     Packing Group: III

Proper shipping name: Toxic solid, organic, n.o.s. (Phenylbutazone)"

LKT P3463 Piperacillin Sodium 1 g 74.8 β-lactam; penicillin binding protein inhibitor. "[[2S-[2α,5α,6β(S*)]]-6-[[[[(4-ethyl-2,3-dioxo-1- piperazinyl)carbonyl]amino]-phenylacetyl]amino]-3,3- dimethyl-7-oxo-4-Thia-1-azabicyclo[3.2.0]heptane-2- carboxylic acid, monosodium salt

" Pentcillin; Pipracil; CL 227193; Isipen; T-1220. 59703-84-3 ≥95% 539.54 C23H26N5NaO7S CCN1CCN(C(=O)C1=O)C(=O)NC(C2=CC=CC=C2)C(=O)NC3C4N(C3=O)C(C(S4)(C)C)C(=O)[O-].[Na+] Ambient Ambient Soluble in water and alcohols. "Fernández-Canigia L, Litterio M, Legaria MC, et al. First national survey of antibiotic susceptibility of the Bacteroides fragilis group: emerging resistance to carbapenems in Argentina. Antimicrob Agents Chemother. 2012 Mar;56(3):1309-14. PMID: 22232282.

Bonfiglio G, Laksai Y, Franceschini N, et al. In vitro activity of piperacillin/tazobactam against 615 Pseudomonas aeruginosa strains isolated in intensive care units. Chemotherapy. 1998 Sep-Oct;44(5):305-12. PMID: 9732144.

Kadima TA, Weiner JH. Mechanism of suppression of piperacillin resistance in enterobacteria by tazobactam. Antimicrob Agents Chemother. 1997 Oct;41(10):2177-83. PMID: 9333044.

" Not dangerous goods.

LKT P3463 Piperacillin Sodium 5 g 312.6 β-lactam; penicillin binding protein inhibitor. "[[2S-[2α,5α,6β(S*)]]-6-[[[[(4-ethyl-2,3-dioxo-1- piperazinyl)carbonyl]amino]-phenylacetyl]amino]-3,3- dimethyl-7-oxo-4-Thia-1-azabicyclo[3.2.0]heptane-2- carboxylic acid, monosodium salt

" Pentcillin; Pipracil; CL 227193; Isipen; T-1220. 59703-84-3 ≥95% 539.54 C23H26N5NaO7S CCN1CCN(C(=O)C1=O)C(=O)NC(C2=CC=CC=C2)C(=O)NC3C4N(C3=O)C(C(S4)(C)C)C(=O)[O-].[Na+] Ambient Ambient Soluble in water and alcohols. "Fernández-Canigia L, Litterio M, Legaria MC, et al. First national survey of antibiotic susceptibility of the Bacteroides fragilis group: emerging resistance to carbapenems in Argentina. Antimicrob Agents Chemother. 2012 Mar;56(3):1309-14. PMID: 22232282.

Bonfiglio G, Laksai Y, Franceschini N, et al. In vitro activity of piperacillin/tazobactam against 615 Pseudomonas aeruginosa strains isolated in intensive care units. Chemotherapy. 1998 Sep-Oct;44(5):305-12. PMID: 9732144.

Kadima TA, Weiner JH. Mechanism of suppression of piperacillin resistance in enterobacteria by tazobactam. Antimicrob Agents Chemother. 1997 Oct;41(10):2177-83. PMID: 9333044.

" Not dangerous goods.

LKT P2815 Phenylbutyrate Sodium 1 g 57.8 HDAC inhibitor. Benzenebutanoic acid, sodium salt Buphenyl; Sodium 4-phenylbutyrate; Tributyrate 1716-12-7 ≥98% 186.18 C10H11O2Na C1=CC=C(C=C1)CCCC(=O)[O-].[Na+] Ambient Ambient Soluble in water, ethanol, DMSO. "Cuadrado-Tejedor M, Ricobaraza AL, Torrijo R, et al. Phenylbutyrate is a multifaceted drug that exerts neuroprotective effects and reverses the Alzheimer´s disease-like phenotype of a commonly used mouse model. Curr Pharm Des. 2013;19(28):5076-84. PMID: 23448463.

Dovzhanskiy DI, Hartwig W, Lázár NG, et al. Growth inhibition of pancreatic cancer by experimental treatment with 4-phenylbutyrate is associated with increased expression of Connexin 43. Oncol Res. 2012;20(2-3):103-11. PMID: 23193916.

Iannitti T, Palmieri B. Clinical and experimental applications of sodium phenylbutyrate. Drugs R D. 2011 Sep 1;11(3):227-49. PMID: 21902286.

Batshaw ML, MacArthur RB, Tuchman M. Alternative pathway therapy for urea cycle disorders: twenty years later. J Pediatr. 2001 Jan;138(1 Suppl):S46-54; Erratum in: J Pediatr 2002 Apr;140(4):490.  PMID: 11148549.

" Xi Not dangerous goods.

LKT P2815 Phenylbutyrate Sodium 5 g 187.8 HDAC inhibitor. Benzenebutanoic acid, sodium salt Buphenyl; Sodium 4-phenylbutyrate; Tributyrate 1716-12-7 ≥98% 186.18 C10H11O2Na C1=CC=C(C=C1)CCCC(=O)[O-].[Na+] Ambient Ambient Soluble in water, ethanol, DMSO. "Cuadrado-Tejedor M, Ricobaraza AL, Torrijo R, et al. Phenylbutyrate is a multifaceted drug that exerts neuroprotective effects and reverses the Alzheimer´s disease-like phenotype of a commonly used mouse model. Curr Pharm Des. 2013;19(28):5076-84. PMID: 23448463.

Dovzhanskiy DI, Hartwig W, Lázár NG, et al. Growth inhibition of pancreatic cancer by experimental treatment with 4-phenylbutyrate is associated with increased expression of Connexin 43. Oncol Res. 2012;20(2-3):103-11. PMID: 23193916.

Iannitti T, Palmieri B. Clinical and experimental applications of sodium phenylbutyrate. Drugs R D. 2011 Sep 1;11(3):227-49. PMID: 21902286.

Batshaw ML, MacArthur RB, Tuchman M. Alternative pathway therapy for urea cycle disorders: twenty years later. J Pediatr. 2001 Jan;138(1 Suppl):S46-54; Erratum in: J Pediatr 2002 Apr;140(4):490.  PMID: 11148549.

" Xi Not dangerous goods.

LKT P2815 Phenylbutyrate Sodium 25 g 749.4 HDAC inhibitor. Benzenebutanoic acid, sodium salt Buphenyl; Sodium 4-phenylbutyrate; Tributyrate 1716-12-7 ≥98% 186.18 C10H11O2Na C1=CC=C(C=C1)CCCC(=O)[O-].[Na+] Ambient Ambient Soluble in water, ethanol, DMSO. "Cuadrado-Tejedor M, Ricobaraza AL, Torrijo R, et al. Phenylbutyrate is a multifaceted drug that exerts neuroprotective effects and reverses the Alzheimer´s disease-like phenotype of a commonly used mouse model. Curr Pharm Des. 2013;19(28):5076-84. PMID: 23448463.

Dovzhanskiy DI, Hartwig W, Lázár NG, et al. Growth inhibition of pancreatic cancer by experimental treatment with 4-phenylbutyrate is associated with increased expression of Connexin 43. Oncol Res. 2012;20(2-3):103-11. PMID: 23193916.

Iannitti T, Palmieri B. Clinical and experimental applications of sodium phenylbutyrate. Drugs R D. 2011 Sep 1;11(3):227-49. PMID: 21902286.

Batshaw ML, MacArthur RB, Tuchman M. Alternative pathway therapy for urea cycle disorders: twenty years later. J Pediatr. 2001 Jan;138(1 Suppl):S46-54; Erratum in: J Pediatr 2002 Apr;140(4):490.  PMID: 11148549.

" Xi Not dangerous goods.

LKT P3463 Piperacillin Sodium 10 g 536.3 β-lactam; penicillin binding protein inhibitor. "[[2S-[2α,5α,6β(S*)]]-6-[[[[(4-ethyl-2,3-dioxo-1- piperazinyl)carbonyl]amino]-phenylacetyl]amino]-3,3- dimethyl-7-oxo-4-Thia-1-azabicyclo[3.2.0]heptane-2- carboxylic acid, monosodium salt

" Pentcillin; Pipracil; CL 227193; Isipen; T-1220. 59703-84-3 ≥95% 539.54 C23H26N5NaO7S CCN1CCN(C(=O)C1=O)C(=O)NC(C2=CC=CC=C2)C(=O)NC3C4N(C3=O)C(C(S4)(C)C)C(=O)[O-].[Na+] Ambient Ambient Soluble in water and alcohols. "Fernández-Canigia L, Litterio M, Legaria MC, et al. First national survey of antibiotic susceptibility of the Bacteroides fragilis group: emerging resistance to carbapenems in Argentina. Antimicrob Agents Chemother. 2012 Mar;56(3):1309-14. PMID: 22232282.

Bonfiglio G, Laksai Y, Franceschini N, et al. In vitro activity of piperacillin/tazobactam against 615 Pseudomonas aeruginosa strains isolated in intensive care units. Chemotherapy. 1998 Sep-Oct;44(5):305-12. PMID: 9732144.

Kadima TA, Weiner JH. Mechanism of suppression of piperacillin resistance in enterobacteria by tazobactam. Antimicrob Agents Chemother. 1997 Oct;41(10):2177-83. PMID: 9333044.

" Not dangerous goods.

LKT P2816 S-(N-3-Phenylpropylthiocarbamoyl)-L-cysteine 100 mg 70.2 Cysteine-ITC conjugate. S-(N-(3-Phenylpropyl)(thiocarbamoyl))-cysteine 137915-13-0 ≥98% 298.42 C13H18N2O2S2 C1=CC=C(C=C1)CCCNC(=S)SCC(C(=O)O)N Ambient -20°C "Tayem Y, Green CJ, Motterlini R, et al. Isothiocyanate-cysteine conjugates protect renal tissue against cisplatin-induced apoptosis via induction of heme oxygenase-1. Pharmacol Res. 2014 Mar;81:1-9. PMID: 24434421.

Hecht SS, Upadhyaya P, Wang M, et al. Inhibition of lung tumorigenesis in A/J mice by N-acetyl-S-(N-2-phenethylthiocarbamoyl)-L-cysteine and myo-inositol, individually and in combination. Carcinogenesis. 2002 Sep;23(9):1455-61. PMID: 12189187.

" Not dangerous goods.

LKT P2816 S-(N-3-Phenylpropylthiocarbamoyl)-L-cysteine 500 mg 209.1 Cysteine-ITC conjugate. S-(N-(3-Phenylpropyl)(thiocarbamoyl))-cysteine 137915-13-0 ≥98% 298.42 C13H18N2O2S2 C1=CC=C(C=C1)CCCNC(=S)SCC(C(=O)O)N Ambient -20°C "Tayem Y, Green CJ, Motterlini R, et al. Isothiocyanate-cysteine conjugates protect renal tissue against cisplatin-induced apoptosis via induction of heme oxygenase-1. Pharmacol Res. 2014 Mar;81:1-9. PMID: 24434421.

Hecht SS, Upadhyaya P, Wang M, et al. Inhibition of lung tumorigenesis in A/J mice by N-acetyl-S-(N-2-phenethylthiocarbamoyl)-L-cysteine and myo-inositol, individually and in combination. Carcinogenesis. 2002 Sep;23(9):1455-61. PMID: 12189187.

" Not dangerous goods.

LKT P2816 S-(N-3-Phenylpropylthiocarbamoyl)-L-cysteine 1 g 369.6 Cysteine-ITC conjugate. S-(N-(3-Phenylpropyl)(thiocarbamoyl))-cysteine 137915-13-0 ≥98% 298.42 C13H18N2O2S2 C1=CC=C(C=C1)CCCNC(=S)SCC(C(=O)O)N Ambient -20°C "Tayem Y, Green CJ, Motterlini R, et al. Isothiocyanate-cysteine conjugates protect renal tissue against cisplatin-induced apoptosis via induction of heme oxygenase-1. Pharmacol Res. 2014 Mar;81:1-9. PMID: 24434421.

Hecht SS, Upadhyaya P, Wang M, et al. Inhibition of lung tumorigenesis in A/J mice by N-acetyl-S-(N-2-phenethylthiocarbamoyl)-L-cysteine and myo-inositol, individually and in combination. Carcinogenesis. 2002 Sep;23(9):1455-61. PMID: 12189187.

" Not dangerous goods.

LKT P2817 Phentolamine Hydrochloride 50 mg 57.8 ATP-sensitive K+ channel activator, α-adrenergic antagonist. 3-[[(4,5-Dihydro-1H-imidazol-2-yl)methyl](4-methyl- phenyl)amino]phenol hydrochloride 73-05-2 ≥98% 317.81 C17H19N3O HCl CC1=CC=C(C=C1)N(CC2=NCCN2)C3=CC(=CC=C3)O.Cl Aqueous solutions cannot be stored. Ambient Ambient Soluble in water (1g/50mL) and alcohol (1g/70mL). Slightly soluble in chloroform. Practically insoluble in acetone and ethyl acetate. "Zhou K, Kumar U, Yuen VG, et al. The effects of phentolamine on fructose-fed rats. Can J Physiol Pharmacol. 2012 Aug;90(8):1075-85. PMID: 22783820.

Ahn SW, Kim SH, Kim JH, et al. Phentolamine inhibits the pacemaker activity of mouse interstitial cells of Cajal by activating ATP-sensitive K+ channels. Arch Pharm Res. 2010 Mar;33(3):479-89. PMID: 20361315.

Dinsmore WW, Wyllie MG. Vasoactive intestinal polypeptide/phentolamine for intracavernosal injection in erectile dysfunction. BJU Int. 2008 Sep;102(8):933-7. PMID: 18485029.

" Xn Not dangerous goods.

LKT P2817 Phentolamine Hydrochloride 100 mg 86.4 ATP-sensitive K+ channel activator, α-adrenergic antagonist. 3-[[(4,5-Dihydro-1H-imidazol-2-yl)methyl](4-methyl- phenyl)amino]phenol hydrochloride 73-05-2 ≥98% 317.81 C17H19N3O HCl CC1=CC=C(C=C1)N(CC2=NCCN2)C3=CC(=CC=C3)O.Cl Aqueous solutions cannot be stored. Ambient Ambient Soluble in water (1g/50mL) and alcohol (1g/70mL). Slightly soluble in chloroform. Practically insoluble in acetone and ethyl acetate. "Zhou K, Kumar U, Yuen VG, et al. The effects of phentolamine on fructose-fed rats. Can J Physiol Pharmacol. 2012 Aug;90(8):1075-85. PMID: 22783820.

Ahn SW, Kim SH, Kim JH, et al. Phentolamine inhibits the pacemaker activity of mouse interstitial cells of Cajal by activating ATP-sensitive K+ channels. Arch Pharm Res. 2010 Mar;33(3):479-89. PMID: 20361315.

Dinsmore WW, Wyllie MG. Vasoactive intestinal polypeptide/phentolamine for intracavernosal injection in erectile dysfunction. BJU Int. 2008 Sep;102(8):933-7. PMID: 18485029.

" Xn Not dangerous goods.

LKT P2817 Phentolamine Hydrochloride 500 mg 333.7 ATP-sensitive K+ channel activator, α-adrenergic antagonist. 3-[[(4,5-Dihydro-1H-imidazol-2-yl)methyl](4-methyl- phenyl)amino]phenol hydrochloride 73-05-2 ≥98% 317.81 C17H19N3O HCl CC1=CC=C(C=C1)N(CC2=NCCN2)C3=CC(=CC=C3)O.Cl Aqueous solutions cannot be stored. Ambient Ambient Soluble in water (1g/50mL) and alcohol (1g/70mL). Slightly soluble in chloroform. Practically insoluble in acetone and ethyl acetate. "Zhou K, Kumar U, Yuen VG, et al. The effects of phentolamine on fructose-fed rats. Can J Physiol Pharmacol. 2012 Aug;90(8):1075-85. PMID: 22783820.

Ahn SW, Kim SH, Kim JH, et al. Phentolamine inhibits the pacemaker activity of mouse interstitial cells of Cajal by activating ATP-sensitive K+ channels. Arch Pharm Res. 2010 Mar;33(3):479-89. PMID: 20361315.

Dinsmore WW, Wyllie MG. Vasoactive intestinal polypeptide/phentolamine for intracavernosal injection in erectile dysfunction. BJU Int. 2008 Sep;102(8):933-7. PMID: 18485029.

" Xn Not dangerous goods.

LKT P3462 Piperacillin 1 g 69.3 β-lactam; penicillin binding protein inhibitor. "[[2S-[2α,5α,6β(S*)]]-6-[[[[(4-ethyl-2,3-dioxo-1- piperazinyl)carbonyl]amino]-phenylacetyl]amino]-3,3- dimethyl-7-oxo-4-Thia-1-azabicyclo[3.2.0]heptane-2- carboxylic acid

" CCRIS 7362; EINECS 262-811-8 61477-96-1 ≥95% 517.56 C23H27N5O7S CCN1CCN(C(=O)C1=O)C(=O)NC(C2=CC=CC=C2)C(=O)NC3C4N(C3=O)C(C(S4)(C)C)C(=O)O Ambient Ambient Soluble in water. "Fernández-Canigia L, Litterio M, Legaria MC, et al. First national survey of antibiotic susceptibility of the Bacteroides fragilis group: emerging resistance to carbapenems in Argentina. Antimicrob Agents Chemother. 2012 Mar;56(3):1309-14. PMID: 22232282.

Bonfiglio G, Laksai Y, Franceschini N, et al. In vitro activity of piperacillin/tazobactam against 615 Pseudomonas aeruginosa strains isolated in intensive care units. Chemotherapy. 1998 Sep-Oct;44(5):305-12. PMID: 9732144.

Kadima TA, Weiner JH. Mechanism of suppression of piperacillin resistance in enterobacteria by tazobactam. Antimicrob Agents Chemother. 1997 Oct;41(10):2177-83. PMID: 9333044.

" Not dangerous goods.

LKT P3462 Piperacillin 5 g 288.8 β-lactam; penicillin binding protein inhibitor. "[[2S-[2α,5α,6β(S*)]]-6-[[[[(4-ethyl-2,3-dioxo-1- piperazinyl)carbonyl]amino]-phenylacetyl]amino]-3,3- dimethyl-7-oxo-4-Thia-1-azabicyclo[3.2.0]heptane-2- carboxylic acid

" CCRIS 7362; EINECS 262-811-8 61477-96-1 ≥95% 517.56 C23H27N5O7S CCN1CCN(C(=O)C1=O)C(=O)NC(C2=CC=CC=C2)C(=O)NC3C4N(C3=O)C(C(S4)(C)C)C(=O)O Ambient Ambient Soluble in water. "Fernández-Canigia L, Litterio M, Legaria MC, et al. First national survey of antibiotic susceptibility of the Bacteroides fragilis group: emerging resistance to carbapenems in Argentina. Antimicrob Agents Chemother. 2012 Mar;56(3):1309-14. PMID: 22232282.

Bonfiglio G, Laksai Y, Franceschini N, et al. In vitro activity of piperacillin/tazobactam against 615 Pseudomonas aeruginosa strains isolated in intensive care units. Chemotherapy. 1998 Sep-Oct;44(5):305-12. PMID: 9732144.

Kadima TA, Weiner JH. Mechanism of suppression of piperacillin resistance in enterobacteria by tazobactam. Antimicrob Agents Chemother. 1997 Oct;41(10):2177-83. PMID: 9333044.

" Not dangerous goods.

LKT P3462 Piperacillin 10 g 508.3 β-lactam; penicillin binding protein inhibitor. "[[2S-[2α,5α,6β(S*)]]-6-[[[[(4-ethyl-2,3-dioxo-1- piperazinyl)carbonyl]amino]-phenylacetyl]amino]-3,3- dimethyl-7-oxo-4-Thia-1-azabicyclo[3.2.0]heptane-2- carboxylic acid

" CCRIS 7362; EINECS 262-811-8 61477-96-1 ≥95% 517.56 C23H27N5O7S CCN1CCN(C(=O)C1=O)C(=O)NC(C2=CC=CC=C2)C(=O)NC3C4N(C3=O)C(C(S4)(C)C)C(=O)O Ambient Ambient Soluble in water. "Fernández-Canigia L, Litterio M, Legaria MC, et al. First national survey of antibiotic susceptibility of the Bacteroides fragilis group: emerging resistance to carbapenems in Argentina. Antimicrob Agents Chemother. 2012 Mar;56(3):1309-14. PMID: 22232282.

Bonfiglio G, Laksai Y, Franceschini N, et al. In vitro activity of piperacillin/tazobactam against 615 Pseudomonas aeruginosa strains isolated in intensive care units. Chemotherapy. 1998 Sep-Oct;44(5):305-12. PMID: 9732144.

Kadima TA, Weiner JH. Mechanism of suppression of piperacillin resistance in enterobacteria by tazobactam. Antimicrob Agents Chemother. 1997 Oct;41(10):2177-83. PMID: 9333044.

" Not dangerous goods.

LKT P2818 Phentolamine Methanesulfonate 50 mg 40.7 ATP-sensitive K+ channel activator, α-adrenergic antagonist. 3-[[(4,5-Dihydro-1H-imidazol-2-yl)methyl](4-methyl- phenyl)amino]phenol methanesulfonate Phentolamine mesylate; Regitine; Rogitine 65-28-1 ≥98% 377.46 C17H19N3O CH3SO3H CC1=CC=C(C=C1)N(CC2=NCCN2)C3=CC(=CC=C3)O.CS(=O)(=O)O Aqueous solutions cannot be stored. Ambient Ambient Soluble in water, alcohol and chloroform. "Zhou K, Kumar U, Yuen VG, et al. The effects of phentolamine on fructose-fed rats. Can J Physiol Pharmacol. 2012 Aug;90(8):1075-85. PMID: 22783820.

Ahn SW, Kim SH, Kim JH, et al. Phentolamine inhibits the pacemaker activity of mouse interstitial cells of Cajal by activating ATP-sensitive K+ channels. Arch Pharm Res. 2010 Mar;33(3):479-89. PMID: 20361315.

Dinsmore WW, Wyllie MG. Vasoactive intestinal polypeptide/phentolamine for intracavernosal injection in erectile dysfunction. BJU Int. 2008 Sep;102(8):933-7. PMID: 18485029.

" Xn Not dangerous goods.

LKT P2818 Phentolamine Methanesulfonate 100 mg 67.9 ATP-sensitive K+ channel activator, α-adrenergic antagonist. 3-[[(4,5-Dihydro-1H-imidazol-2-yl)methyl](4-methyl- phenyl)amino]phenol methanesulfonate Phentolamine mesylate; Regitine; Rogitine 65-28-1 ≥98% 377.46 C17H19N3O CH3SO3H CC1=CC=C(C=C1)N(CC2=NCCN2)C3=CC(=CC=C3)O.CS(=O)(=O)O Aqueous solutions cannot be stored. Ambient Ambient Soluble in water, alcohol and chloroform. "Zhou K, Kumar U, Yuen VG, et al. The effects of phentolamine on fructose-fed rats. Can J Physiol Pharmacol. 2012 Aug;90(8):1075-85. PMID: 22783820.

Ahn SW, Kim SH, Kim JH, et al. Phentolamine inhibits the pacemaker activity of mouse interstitial cells of Cajal by activating ATP-sensitive K+ channels. Arch Pharm Res. 2010 Mar;33(3):479-89. PMID: 20361315.

Dinsmore WW, Wyllie MG. Vasoactive intestinal polypeptide/phentolamine for intracavernosal injection in erectile dysfunction. BJU Int. 2008 Sep;102(8):933-7. PMID: 18485029.

" Xn Not dangerous goods.

LKT P2818 Phentolamine Methanesulfonate 500 mg 203.8 ATP-sensitive K+ channel activator, α-adrenergic antagonist. 3-[[(4,5-Dihydro-1H-imidazol-2-yl)methyl](4-methyl- phenyl)amino]phenol methanesulfonate Phentolamine mesylate; Regitine; Rogitine 65-28-1 ≥98% 377.46 C17H19N3O CH3SO3H CC1=CC=C(C=C1)N(CC2=NCCN2)C3=CC(=CC=C3)O.CS(=O)(=O)O Aqueous solutions cannot be stored. Ambient Ambient Soluble in water, alcohol and chloroform. "Zhou K, Kumar U, Yuen VG, et al. The effects of phentolamine on fructose-fed rats. Can J Physiol Pharmacol. 2012 Aug;90(8):1075-85. PMID: 22783820.

Ahn SW, Kim SH, Kim JH, et al. Phentolamine inhibits the pacemaker activity of mouse interstitial cells of Cajal by activating ATP-sensitive K+ channels. Arch Pharm Res. 2010 Mar;33(3):479-89. PMID: 20361315.

Dinsmore WW, Wyllie MG. Vasoactive intestinal polypeptide/phentolamine for intracavernosal injection in erectile dysfunction. BJU Int. 2008 Sep;102(8):933-7. PMID: 18485029.

" Xn Not dangerous goods.

LKT P2819 6-Phenylhexa-3,5-dien-2-one 5 mg 268.9 Minor kavalactone originally found in Piper methysticum (kava plant). EINECS 224-036-3 4173-44-8 ≥96% 172.22 C12H12O CC(=O)C=CC=CC1=CC=CC=C1 Ambient -20°C "Siddiqui BS, Gulzar T, Begum S, et al. A new natural product and insecticidal amides from seeds of Piper nigrum Linn. Nat Prod Res. 2008;22(13):1107-11. PMID: 18855209.

" Not dangerous goods.

LKT P2819 6-Phenylhexa-3,5-dien-2-one 10 mg 461 Minor kavalactone originally found in Piper methysticum (kava plant). EINECS 224-036-3 4173-44-8 ≥96% 172.22 C12H12O CC(=O)C=CC=CC1=CC=CC=C1 Ambient -20°C "Siddiqui BS, Gulzar T, Begum S, et al. A new natural product and insecticidal amides from seeds of Piper nigrum Linn. Nat Prod Res. 2008;22(13):1107-11. PMID: 18855209.

" Not dangerous goods.

LKT P2832 Peptide Histidine Isoleucine, pig 1 mg 470.4 Endogenous peptide, involved in prolactin signaling, circadian rhythms, feeding behavior; VPAC2 agonist. PHI 80458-29-3 ≥97% 2995.39 C136H216N36O40 CCC(C)C(C(=O)N)NC(=O)C(CC(C)C)NC(=O)C(CO)NC(=O)C(CCC(=O)O)NC(=O)C(CC(C)C)NC(=O)C(CC1=CC=C(C=C1)O)NC(=O)C(CCCCN)NC(=O)C(CCCCN)NC(=O)C(C)NC(=O)C(CO)NC(=O)C(CC(C)C)NC(=O)C(CCC(=O)N)NC(=O)CNC(=O)C(CC(C)C)NC(=O)C(CC(C)C)NC(=O)C(CCCNC(=N)N)NC(=O)C(CO)NC(=O)C(CC2=CC=CC=C2)NC(=O)C(CC(=O)O)NC(=O)C(CO)NC(=O)C(C(C)O)NC(=O)C(CC3=CC=CC=C3)NC(=O)C(C(C)C)NC(=O)CNC(=O)C(CC(=O)O)NC(=O)C(C)NC(=O)C(CC4=CN=CN4)N Ambient -20°C "Goursaud S, Focant MC, Berger JV, et al. The VPAC2 agonist peptide histidine isoleucine (PHI) up-regulates glutamate transport in the corpus callosum of a rat model of amyotrophic lateral sclerosis (hSOD1G93A) by inhibiting caspase-3 mediated inactivation of GLT-1a. FASEB J. 2011 Oct;25(10):3674-86. PMID: 21730107.

Colwell CS, Michel S, Itri J, et al. Disrupted circadian rhythms in VIP- and PHI-deficient mice. Am J Physiol Regul Integr Comp Physiol. 2003 Nov;285(5):R939-49. PMID: 12855416.

Olszewski PK, Wirth MM, Shaw TJ, et al. Peptides that regulate food intake: effect of peptide histidine isoleucine on consummatory behavior in rats. Am J Physiol Regul Integr Comp Physiol. 2003 Jun;284(6):R1445-53. PMID: 12595279.

Lelièvre V, Pineau N, Du J, et al. Differential effects of peptide histidine isoleucine (PHI) and related peptides on stimulation and suppression of neuroblastoma cell proliferation. A novel VIP-independent action of PHI via MAP kinase. J Biol Chem. 1998 Jul 31;273(31):19685-90. PMID: 9677397.

"

LKT P3348 Pimecrolimus 5 mg 103.6 Calcineurin inhibitor, potential TRPV1 agonist. 137071-32-0 ≥98% 810.45 C43H66ClNO11 CCC1C=C(CC(CC(C2C(CC(C(O2)(C(=O)C(=O)N3CCCCC3C(=O)OC(C(C(CC1=O)O)C)C(=CC4CCC(C(C4)OC)Cl)C)O)C)OC)OC)C)C Ambient Ambient "Xie ZQ, Lan YZ. Effectiveness of pimecrolimus cream for women patients with sensitive skin and its underlying mechanism. Zhongguo Yi Xue Ke Xue Yuan Xue Bao. 2012 Aug;34(4):375-8. PMID: 22954121.

Lampropoulos CE, D'Cruz DP. Topical calcineurin inhibitors in systemic lupus erythematosus. Ther Clin Risk Manag. 2010 Apr 15;6:95-101. PMID: 20421909.

Hultsch T, Kapp A, Spergel J. Immunomodulation and safety of topical calcineurin inhibitors for the treatment of atopic dermatitis. Dermatology. 2005;211(2):174-87. Review. Erratum in: Dermatology. 2005;211(3):292.  PMID: 16088174.

Lipozencić J. Pimecrolimus--a safe and effective local immunomodulator in the treatment of inflammatory skin diseases. Acta Dermatovenerol Croat. 2005;13(1):63-9. PMID: 15788149.

Gupta AK, Chow M. Pimecrolimus: a review. J Eur Acad Dermatol Venereol. 2003 Sep;17(5):493-503. PMID: 12941081.

" Not dangerous goods.

LKT P3348 Pimecrolimus 25 mg 388.3 Calcineurin inhibitor, potential TRPV1 agonist. 137071-32-0 ≥98% 810.45 C43H66ClNO11 CCC1C=C(CC(CC(C2C(CC(C(O2)(C(=O)C(=O)N3CCCCC3C(=O)OC(C(C(CC1=O)O)C)C(=CC4CCC(C(C4)OC)Cl)C)O)C)OC)OC)C)C Ambient Ambient "Xie ZQ, Lan YZ. Effectiveness of pimecrolimus cream for women patients with sensitive skin and its underlying mechanism. Zhongguo Yi Xue Ke Xue Yuan Xue Bao. 2012 Aug;34(4):375-8. PMID: 22954121.

Lampropoulos CE, D'Cruz DP. Topical calcineurin inhibitors in systemic lupus erythematosus. Ther Clin Risk Manag. 2010 Apr 15;6:95-101. PMID: 20421909.

Hultsch T, Kapp A, Spergel J. Immunomodulation and safety of topical calcineurin inhibitors for the treatment of atopic dermatitis. Dermatology. 2005;211(2):174-87. Review. Erratum in: Dermatology. 2005;211(3):292.  PMID: 16088174.

Lipozencić J. Pimecrolimus--a safe and effective local immunomodulator in the treatment of inflammatory skin diseases. Acta Dermatovenerol Croat. 2005;13(1):63-9. PMID: 15788149.

Gupta AK, Chow M. Pimecrolimus: a review. J Eur Acad Dermatol Venereol. 2003 Sep;17(5):493-503. PMID: 12941081.

" Not dangerous goods.

LKT P2833 Peptide Histidine Isoleucine, rat 0.5 mg 204.1 Endogenous peptide hormone; VPAC2 activator. Rat peptide histidineisoleucine; PHI 96849-38-6 ≥95% 3011.45 C136H216N36O41 "CCC(C)C(C(=O)N)NC(=O)C(CC(C)C)NC(=O)C(CO)NC(=O)C(CCC(=O)O)NC(=O)C(CC(C)C)NC(=O)C(Cc1ccc(cc1)O)NC(=O)C(CCCCN)NC(=O)C(CCCCN)NC(=O)C(C)NC(=O)C(CO)NC(=O)C(CC(C)C)NC(=O)C(CCC(=O)N)NC(=O)CNC(=O)C(CC(C)C)NC(=O)C(CC(C)C)NC(=O)C(CCCNC(=N)N)NC(=O)C(CO)NC(=O)C(Cc2ccc(cc2)O)NC(=O)C(CC(=O)O)NC(=O)C(CO)NC(=O)C(C(C)O)NC(=O)C(Cc3ccccc3)NC(=O)C(C(C)C)NC(=O)CNC(=O)C(CC(=O)O)NC(=O)C(C)NC(=O)C(Cc4cnc[nH]4)N

" Ambient -20°C "Goursaud S, Focant MC, Berger JV, et al. The VPAC2 agonist peptide histidine isoleucine (PHI) up-regulates glutamate transport in the corpus callosum of a rat model of amyotrophic lateral sclerosis (hSOD1G93A) by inhibiting caspase-3 mediated inactivation of GLT-1a. FASEB J. 2011 Oct;25(10):3674-86. PMID: 21730107.

Colwell CS, Michel S, Itri J, et al. Disrupted circadian rhythms in VIP- and PHI-deficient mice. Am J Physiol Regul Integr Comp Physiol. 2003 Nov;285(5):R939-49. PMID: 12855416.

Olszewski PK, Wirth MM, Shaw TJ, et al. Peptides that regulate food intake: effect of peptide histidine isoleucine on consummatory behavior in rats. Am J Physiol Regul Integr Comp Physiol. 2003 Jun;284(6):R1445-53. PMID: 12595279.

Lelièvre V, Pineau N, Du J, et al. Differential effects of peptide histidine isoleucine (PHI) and related peptides on stimulation and suppression of neuroblastoma cell proliferation. A novel VIP-independent action of PHI via MAP kinase. J Biol Chem. 1998 Jul 31;273(31):19685-90. PMID: 9677397.

"

LKT P2833 Peptide Histidine Isoleucine, rat 1 mg 348 Endogenous peptide hormone; VPAC2 activator. Rat peptide histidineisoleucine; PHI 96849-38-6 ≥95% 3011.45 C136H216N36O41 "CCC(C)C(C(=O)N)NC(=O)C(CC(C)C)NC(=O)C(CO)NC(=O)C(CCC(=O)O)NC(=O)C(CC(C)C)NC(=O)C(Cc1ccc(cc1)O)NC(=O)C(CCCCN)NC(=O)C(CCCCN)NC(=O)C(C)NC(=O)C(CO)NC(=O)C(CC(C)C)NC(=O)C(CCC(=O)N)NC(=O)CNC(=O)C(CC(C)C)NC(=O)C(CC(C)C)NC(=O)C(CCCNC(=N)N)NC(=O)C(CO)NC(=O)C(Cc2ccc(cc2)O)NC(=O)C(CC(=O)O)NC(=O)C(CO)NC(=O)C(C(C)O)NC(=O)C(Cc3ccccc3)NC(=O)C(C(C)C)NC(=O)CNC(=O)C(CC(=O)O)NC(=O)C(C)NC(=O)C(Cc4cnc[nH]4)N

" Ambient -20°C "Goursaud S, Focant MC, Berger JV, et al. The VPAC2 agonist peptide histidine isoleucine (PHI) up-regulates glutamate transport in the corpus callosum of a rat model of amyotrophic lateral sclerosis (hSOD1G93A) by inhibiting caspase-3 mediated inactivation of GLT-1a. FASEB J. 2011 Oct;25(10):3674-86. PMID: 21730107.

Colwell CS, Michel S, Itri J, et al. Disrupted circadian rhythms in VIP- and PHI-deficient mice. Am J Physiol Regul Integr Comp Physiol. 2003 Nov;285(5):R939-49. PMID: 12855416.

Olszewski PK, Wirth MM, Shaw TJ, et al. Peptides that regulate food intake: effect of peptide histidine isoleucine on consummatory behavior in rats. Am J Physiol Regul Integr Comp Physiol. 2003 Jun;284(6):R1445-53. PMID: 12595279.

Lelièvre V, Pineau N, Du J, et al. Differential effects of peptide histidine isoleucine (PHI) and related peptides on stimulation and suppression of neuroblastoma cell proliferation. A novel VIP-independent action of PHI via MAP kinase. J Biol Chem. 1998 Jul 31;273(31):19685-90. PMID: 9677397.

"

LKT P2833 Peptide Histidine Isoleucine, rat 2.5 mg 612.4 Endogenous peptide hormone; VPAC2 activator. Rat peptide histidineisoleucine; PHI 96849-38-6 ≥95% 3011.45 C136H216N36O41 "CCC(C)C(C(=O)N)NC(=O)C(CC(C)C)NC(=O)C(CO)NC(=O)C(CCC(=O)O)NC(=O)C(CC(C)C)NC(=O)C(Cc1ccc(cc1)O)NC(=O)C(CCCCN)NC(=O)C(CCCCN)NC(=O)C(C)NC(=O)C(CO)NC(=O)C(CC(C)C)NC(=O)C(CCC(=O)N)NC(=O)CNC(=O)C(CC(C)C)NC(=O)C(CC(C)C)NC(=O)C(CCCNC(=N)N)NC(=O)C(CO)NC(=O)C(Cc2ccc(cc2)O)NC(=O)C(CC(=O)O)NC(=O)C(CO)NC(=O)C(C(C)O)NC(=O)C(Cc3ccccc3)NC(=O)C(C(C)C)NC(=O)CNC(=O)C(CC(=O)O)NC(=O)C(C)NC(=O)C(Cc4cnc[nH]4)N

" Ambient -20°C "Goursaud S, Focant MC, Berger JV, et al. The VPAC2 agonist peptide histidine isoleucine (PHI) up-regulates glutamate transport in the corpus callosum of a rat model of amyotrophic lateral sclerosis (hSOD1G93A) by inhibiting caspase-3 mediated inactivation of GLT-1a. FASEB J. 2011 Oct;25(10):3674-86. PMID: 21730107.

Colwell CS, Michel S, Itri J, et al. Disrupted circadian rhythms in VIP- and PHI-deficient mice. Am J Physiol Regul Integr Comp Physiol. 2003 Nov;285(5):R939-49. PMID: 12855416.

Olszewski PK, Wirth MM, Shaw TJ, et al. Peptides that regulate food intake: effect of peptide histidine isoleucine on consummatory behavior in rats. Am J Physiol Regul Integr Comp Physiol. 2003 Jun;284(6):R1445-53. PMID: 12595279.

Lelièvre V, Pineau N, Du J, et al. Differential effects of peptide histidine isoleucine (PHI) and related peptides on stimulation and suppression of neuroblastoma cell proliferation. A novel VIP-independent action of PHI via MAP kinase. J Biol Chem. 1998 Jul 31;273(31):19685-90. PMID: 9677397.

"

LKT P2845 Phleomycin 5 mg 83.9 Glycopeptide, metal ion chelator, induces DNA strand breaks. NSC 61586; NSC 616586. 11006-33-0 ≥97% 1326.38 C51H75N17O21S2 CC1=C(N=C(N=C1N)C(CC(=O)N)NCC(C(=O)N)N)C(=O)NC(C(C2=CN=CN2)OC3C(C(C(C(O3)CO)O)O)(C)OC4C(C(C(C(O4)CO)O)(C(=O)N)O)O)C(=O)NC(C)C(C(C)C(=O)NC(C(=O)C)C(=O)NCCC5=NC(CS5)C6=NC(=CS6)C(=O)N)O Very hygroscopic. Store under inert gas Ambient 4°C Soluble in water (10mg/mL); slightly sol in methanol. "van Peer AF, de Bekker C, Vinck A, et al. Phleomycin increases transformation efficiency and promotes single integrations in Schizophyllum commune. Appl Environ Microbiol. 2009 Mar;75(5):1243-7. PMID: 19114524.

Povirk LF, Hogan M, Dattagupta N, et al. Copper(II).bleomycin, iron(III).bleomycin, and copper(II).phleomycin: comparative study of deoxyribonucleic acid binding. Biochemistry. 1981 Feb 3;20(3):665-71. PMID: 6163448.

Sleigh MJ. The mechanism of DNA breakage by phleomycin in vitro. Nucleic Acids Res. 1976 Apr;3(4):891-901. PMID: 818624.

" Xn Not dangerous goods.

LKT P2845 Phleomycin 25 mg 294.1 Glycopeptide, metal ion chelator, induces DNA strand breaks. NSC 61586; NSC 616586. 11006-33-0 ≥97% 1326.38 C51H75N17O21S2 CC1=C(N=C(N=C1N)C(CC(=O)N)NCC(C(=O)N)N)C(=O)NC(C(C2=CN=CN2)OC3C(C(C(C(O3)CO)O)O)(C)OC4C(C(C(C(O4)CO)O)(C(=O)N)O)O)C(=O)NC(C)C(C(C)C(=O)NC(C(=O)C)C(=O)NCCC5=NC(CS5)C6=NC(=CS6)C(=O)N)O Very hygroscopic. Store under inert gas Ambient 4°C Soluble in water (10mg/mL); slightly sol in methanol. "van Peer AF, de Bekker C, Vinck A, et al. Phleomycin increases transformation efficiency and promotes single integrations in Schizophyllum commune. Appl Environ Microbiol. 2009 Mar;75(5):1243-7. PMID: 19114524.

Povirk LF, Hogan M, Dattagupta N, et al. Copper(II).bleomycin, iron(III).bleomycin, and copper(II).phleomycin: comparative study of deoxyribonucleic acid binding. Biochemistry. 1981 Feb 3;20(3):665-71. PMID: 6163448.

Sleigh MJ. The mechanism of DNA breakage by phleomycin in vitro. Nucleic Acids Res. 1976 Apr;3(4):891-901. PMID: 818624.

" Xn Not dangerous goods.

LKT P2845 Phleomycin 100 mg 882.1 Glycopeptide, metal ion chelator, induces DNA strand breaks. NSC 61586; NSC 616586. 11006-33-0 ≥97% 1326.38 C51H75N17O21S2 CC1=C(N=C(N=C1N)C(CC(=O)N)NCC(C(=O)N)N)C(=O)NC(C(C2=CN=CN2)OC3C(C(C(C(O3)CO)O)O)(C)OC4C(C(C(C(O4)CO)O)(C(=O)N)O)O)C(=O)NC(C)C(C(C)C(=O)NC(C(=O)C)C(=O)NCCC5=NC(CS5)C6=NC(=CS6)C(=O)N)O Very hygroscopic. Store under inert gas Ambient 4°C Soluble in water (10mg/mL); slightly sol in methanol. "van Peer AF, de Bekker C, Vinck A, et al. Phleomycin increases transformation efficiency and promotes single integrations in Schizophyllum commune. Appl Environ Microbiol. 2009 Mar;75(5):1243-7. PMID: 19114524.

Povirk LF, Hogan M, Dattagupta N, et al. Copper(II).bleomycin, iron(III).bleomycin, and copper(II).phleomycin: comparative study of deoxyribonucleic acid binding. Biochemistry. 1981 Feb 3;20(3):665-71. PMID: 6163448.

Sleigh MJ. The mechanism of DNA breakage by phleomycin in vitro. Nucleic Acids Res. 1976 Apr;3(4):891-901. PMID: 818624.

" Xn Not dangerous goods.

LKT P2856 Phorbol-12,13-dibutyrate 1 mg 125.9 PKC and PKD activator, carcinogen. PBDu 37558-16-0 ≥98% 504.61 C30H46O8 CCCC(=O)OC1C(C2(C(C=C(CC3(C2C=C(C3=O)C)O)CO)C4C1(C4(C)C)OC(=O)CCC)O)C Ambient -20°C Soluble in DMSO or ethanol. "Aicart-Ramos C, Sánchez-Ruiloba L, Gómez-Parrizas M, et al. Protein kinase D activity controls endothelial nitric oxide synthesis. J Cell Sci. 2014 Aug 1;127(Pt 15):3360-72. PMID: 24928905.

Terui Y, Furukawa Y, Kikuchi J, et al. Apoptosis during HL-60 cell differentiation is closely related to a G0/G1 cell cycle arrest. J Cell Physiol. 1995 Jul;164(1):74-84. PMID: 7790399.

Rais S, Combadiere C, Hakim J, et al. Staurosporine up-regulates the expression of phorbol dibutyrate binding sites in human platelets. Biochem Pharmacol. 1994 May 18;47(10):1797-804. PMID: 8204096.

" Xi Not dangerous goods.

LKT P2856 Phorbol-12,13-dibutyrate 5 mg 297.2 PKC and PKD activator, carcinogen. PBDu 37558-16-0 ≥98% 504.61 C30H46O8 CCCC(=O)OC1C(C2(C(C=C(CC3(C2C=C(C3=O)C)O)CO)C4C1(C4(C)C)OC(=O)CCC)O)C Ambient -20°C Soluble in DMSO or ethanol. "Aicart-Ramos C, Sánchez-Ruiloba L, Gómez-Parrizas M, et al. Protein kinase D activity controls endothelial nitric oxide synthesis. J Cell Sci. 2014 Aug 1;127(Pt 15):3360-72. PMID: 24928905.

Terui Y, Furukawa Y, Kikuchi J, et al. Apoptosis during HL-60 cell differentiation is closely related to a G0/G1 cell cycle arrest. J Cell Physiol. 1995 Jul;164(1):74-84. PMID: 7790399.

Rais S, Combadiere C, Hakim J, et al. Staurosporine up-regulates the expression of phorbol dibutyrate binding sites in human platelets. Biochem Pharmacol. 1994 May 18;47(10):1797-804. PMID: 8204096.

" Xi Not dangerous goods.

LKT P2857 Phorbol-12-myristate-13-acetate 1 mg 78.2 PKC activator, carcinogen. 12-Tetradecanoyl phorbol-13-acetate TPA; PMA; Tetradecanoylphorbol acetate; 4beta-Phorbol 12-myristate 13-acetate; Phorbol ester 16561-29-8 ≥98% 616.84 C36H56O8 CCCCCCCCCCCCCC(=O)OC1C(C2(C(C=C(CC3(C2C=C(C3=O)C)O)CO)C4C1(C4(C)C)OC(=O)C)O)C Ambient -20°C Soluble in DMSO, methanol, ethanol, ethyl acetate, or chloroform. Insoluble in water or aqueous buffer "Poachanukoon O, Koontongkaew S, Monthanapisut P, et al. Macrolides attenuate phorbol ester-induced tumor necrosis factor-α and mucin production from human airway epithelial cells. Pharmacology. 2014;93(1-2):92-9. PMID: 24556631.

Oskoueian E, Abdullah N, Ahmad S. Phorbol esters isolated from Jatropha meal induced apoptosis-mediated inhibition in proliferation of chang and Vero cell lines. Int J Mol Sci. 2012 Oct 24;13(11):13816-29. PMID: 23203036.

Colombo D, Tringali C, Franchini L, et al. Glycoglycerolipid analogues inhibit PKC translocation to the plasma membrane and downstream signaling pathways in PMA-treated fibroblasts and human glioblastoma cells, U87MG. Eur J Med Chem. 2011 May;46(5):1827-34. PMID: 21388717.

Birnboim HC. Factors which affect DNA strand breakage in human leukocytes exposed to a tumor promoter, phorbol myristate acetate. Can J Physiol Pharmacol. 1982 Nov;60(11):1359-66. PMID: 6295575.

" Xi Not dangerous goods.

LKT P2857 Phorbol-12-myristate-13-acetate 5 mg 234 PKC activator, carcinogen. 12-Tetradecanoyl phorbol-13-acetate TPA; PMA; Tetradecanoylphorbol acetate; 4beta-Phorbol 12-myristate 13-acetate; Phorbol ester 16561-29-8 ≥98% 616.84 C36H56O8 CCCCCCCCCCCCCC(=O)OC1C(C2(C(C=C(CC3(C2C=C(C3=O)C)O)CO)C4C1(C4(C)C)OC(=O)C)O)C Ambient -20°C Soluble in DMSO, methanol, ethanol, ethyl acetate, or chloroform. Insoluble in water or aqueous buffer "Poachanukoon O, Koontongkaew S, Monthanapisut P, et al. Macrolides attenuate phorbol ester-induced tumor necrosis factor-α and mucin production from human airway epithelial cells. Pharmacology. 2014;93(1-2):92-9. PMID: 24556631.

Oskoueian E, Abdullah N, Ahmad S. Phorbol esters isolated from Jatropha meal induced apoptosis-mediated inhibition in proliferation of chang and Vero cell lines. Int J Mol Sci. 2012 Oct 24;13(11):13816-29. PMID: 23203036.

Colombo D, Tringali C, Franchini L, et al. Glycoglycerolipid analogues inhibit PKC translocation to the plasma membrane and downstream signaling pathways in PMA-treated fibroblasts and human glioblastoma cells, U87MG. Eur J Med Chem. 2011 May;46(5):1827-34. PMID: 21388717.

Birnboim HC. Factors which affect DNA strand breakage in human leukocytes exposed to a tumor promoter, phorbol myristate acetate. Can J Physiol Pharmacol. 1982 Nov;60(11):1359-66. PMID: 6295575.

" Xi Not dangerous goods.

LKT P3313 Pidotimod 1 g 125.9 Immunostimulator, adjuvant. "(R)-3-((S)-5-Oxoprolyl)-4-thiazolidinecarboxylic acid 

" Axil; Onaka; Pigitil; Polimod 121808-62-6 ≥98% 244.27 C9H12N2O4S C1CC(=O)NC1C(=O)N2CSCC2C(=O)O Ambient Ambient Soluble in water (37.8 g/L), methanol (13.8 g/L), ethanol (4.4 g/L), and DMF (72.4g/L). "Zuccotti GV, Mameli C. Pidotimod: the past and the present. Ital J Pediatr. 2013 Dec 6;39:75. PMID: 24314100.

Zhao Y, Huang B, Huang S, et al. Evaluation of the adjuvant effect of pidotimod on the immune protection induced by UV-attenuated Toxoplasma gondii in mouse models. Parasitol Res. 2013 Sep;112(9):3151-60. PMID: 23783399.

Giagulli C, Noerder M, Avolio M, et al. Pidotimod promotes functional maturation of dendritic cells and displays adjuvant properties at the nasal mucosa level. Int Immunopharmacol. 2009 Nov;9(12):1366-73. PMID: 19712757.

" Not dangerous goods.

LKT P2858 4-α-Phorbol-12-myristate-13-acetate 1 mg 156.6 Negative control for PKC activation. 4-α-12-Tetradecanoyl phorbol-13-acetate 4-αPMA 63597-44-4 ≥98% 616.83 C36H56O8 CCCCCCCCCCCCCC(=O)OC1C(C2(C(C=C(CC3(C2C=C(C3=O)C)O)CO)C4C1(C4(C)C)OC(=O)C)O)C Ambient -20°C Soluble in DMSO, methanol, ethanol, ethyl acetate, or chloroform "Chahine M, Qu Y, Mancarella S, et al. Protein kinase C activation inhibits alpha1D L-type Ca channel: a single-channel analysis. Pflugers Arch. 2008 Feb;455(5):913-9. PMID: 17909852.

Tosco M, Orsenigo MN, Gastaldi G, et al. Protein kinase C regulation of rat jejunal transport system: mechanisms involved in lactate movement. Exp Physiol. 2002 Nov;87(6):653-62. PMID: 12530398.

" Xi Not dangerous goods.

LKT P2858 4-α-Phorbol-12-myristate-13-acetate 5 mg 623.7 Negative control for PKC activation. 4-α-12-Tetradecanoyl phorbol-13-acetate 4-αPMA 63597-44-4 ≥98% 616.83 C36H56O8 CCCCCCCCCCCCCC(=O)OC1C(C2(C(C=C(CC3(C2C=C(C3=O)C)O)CO)C4C1(C4(C)C)OC(=O)C)O)C Ambient -20°C Soluble in DMSO, methanol, ethanol, ethyl acetate, or chloroform "Chahine M, Qu Y, Mancarella S, et al. Protein kinase C activation inhibits alpha1D L-type Ca channel: a single-channel analysis. Pflugers Arch. 2008 Feb;455(5):913-9. PMID: 17909852.

Tosco M, Orsenigo MN, Gastaldi G, et al. Protein kinase C regulation of rat jejunal transport system: mechanisms involved in lactate movement. Exp Physiol. 2002 Nov;87(6):653-62. PMID: 12530398.

" Xi Not dangerous goods.

LKT P3313 Pidotimod 5 g 462.1 Immunostimulator, adjuvant. "(R)-3-((S)-5-Oxoprolyl)-4-thiazolidinecarboxylic acid 

" Axil; Onaka; Pigitil; Polimod 121808-62-6 ≥98% 244.27 C9H12N2O4S C1CC(=O)NC1C(=O)N2CSCC2C(=O)O Ambient Ambient Soluble in water (37.8 g/L), methanol (13.8 g/L), ethanol (4.4 g/L), and DMF (72.4g/L). "Zuccotti GV, Mameli C. Pidotimod: the past and the present. Ital J Pediatr. 2013 Dec 6;39:75. PMID: 24314100.

Zhao Y, Huang B, Huang S, et al. Evaluation of the adjuvant effect of pidotimod on the immune protection induced by UV-attenuated Toxoplasma gondii in mouse models. Parasitol Res. 2013 Sep;112(9):3151-60. PMID: 23783399.

Giagulli C, Noerder M, Avolio M, et al. Pidotimod promotes functional maturation of dendritic cells and displays adjuvant properties at the nasal mucosa level. Int Immunopharmacol. 2009 Nov;9(12):1366-73. PMID: 19712757.

" Not dangerous goods.

LKT P3313 Pidotimod 10 g 808.5 Immunostimulator, adjuvant. "(R)-3-((S)-5-Oxoprolyl)-4-thiazolidinecarboxylic acid 

" Axil; Onaka; Pigitil; Polimod 121808-62-6 ≥98% 244.27 C9H12N2O4S C1CC(=O)NC1C(=O)N2CSCC2C(=O)O Ambient Ambient Soluble in water (37.8 g/L), methanol (13.8 g/L), ethanol (4.4 g/L), and DMF (72.4g/L). "Zuccotti GV, Mameli C. Pidotimod: the past and the present. Ital J Pediatr. 2013 Dec 6;39:75. PMID: 24314100.

Zhao Y, Huang B, Huang S, et al. Evaluation of the adjuvant effect of pidotimod on the immune protection induced by UV-attenuated Toxoplasma gondii in mouse models. Parasitol Res. 2013 Sep;112(9):3151-60. PMID: 23783399.

Giagulli C, Noerder M, Avolio M, et al. Pidotimod promotes functional maturation of dendritic cells and displays adjuvant properties at the nasal mucosa level. Int Immunopharmacol. 2009 Nov;9(12):1366-73. PMID: 19712757.

" Not dangerous goods.

LKT P3269 Piroxicam 1 g 39.5 NSAID; COX-1/2 inhibitor. "4-Hydroxy-2-methyl-N-(2-pyridyl)-2H-1,2-

benzothiazine-3-carboxamide-1,1-dioxide " Feldene; Piroftal; Roxicam 36322-90-4 ≥98% 331.35 C15H13N3O4S CN1C(=C(C2=CC=CC=C2S1(=O)=O)O)C(=O)NC3=CC=CC=N3 Ambient Ambient Insoluble in water. Soluble in acetonitrile. "Chakraborty S, Bose M, Sarkar M. Spectroscopic studies of the binding of Cu(II) complexes of oxicam NSAIDs to alternating G-C and homopolymeric G-C sequences. Spectrochim Acta A Mol Biomol Spectrosc. 2014 Mar 25;122:690-7. PMID: 24345609.

Barkin RL. Topical Nonsteroidal Anti-Inflammatory Drugs: The Importance of Drug, Delivery, and Therapeutic Outcome. Am J Ther. 2012 Feb 22. [Epub ahead of print]. PMID: 22367354.

Tasaki Y, Yamamoto J, Omura T, et al. Oxicam structure in non-steroidal anti-inflammatory drugs is essential to exhibit Akt-mediated neuroprotection against 1-methyl-4-phenyl pyridinium-induced cytotoxicity. Eur J Pharmacol. 2012 Feb 15;676(1-3):57-63. PMID: 22182582.

Qiu ZF, Maruyama K, Sunayama K, et al. Piroxicam-induced regression of intestinal adenomatous polyps in APC(delta474) mice. J Invest Surg. 2003 Mar-Apr;16(2):71-81. PMID: 12746190.

" Xn "UN number: 2811     Class: 6.1     Packing Group: III

Proper shipping name: Toxic solid, organic, n.o.s. (Piroxicam) "

LKT P3269 Piroxicam 5 g 160.7 NSAID; COX-1/2 inhibitor. "4-Hydroxy-2-methyl-N-(2-pyridyl)-2H-1,2-

benzothiazine-3-carboxamide-1,1-dioxide " Feldene; Piroftal; Roxicam 36322-90-4 ≥98% 331.35 C15H13N3O4S CN1C(=C(C2=CC=CC=C2S1(=O)=O)O)C(=O)NC3=CC=CC=N3 Ambient Ambient Insoluble in water. Soluble in acetonitrile. "Chakraborty S, Bose M, Sarkar M. Spectroscopic studies of the binding of Cu(II) complexes of oxicam NSAIDs to alternating G-C and homopolymeric G-C sequences. Spectrochim Acta A Mol Biomol Spectrosc. 2014 Mar 25;122:690-7. PMID: 24345609.

Barkin RL. Topical Nonsteroidal Anti-Inflammatory Drugs: The Importance of Drug, Delivery, and Therapeutic Outcome. Am J Ther. 2012 Feb 22. [Epub ahead of print]. PMID: 22367354.

Tasaki Y, Yamamoto J, Omura T, et al. Oxicam structure in non-steroidal anti-inflammatory drugs is essential to exhibit Akt-mediated neuroprotection against 1-methyl-4-phenyl pyridinium-induced cytotoxicity. Eur J Pharmacol. 2012 Feb 15;676(1-3):57-63. PMID: 22182582.

Qiu ZF, Maruyama K, Sunayama K, et al. Piroxicam-induced regression of intestinal adenomatous polyps in APC(delta474) mice. J Invest Surg. 2003 Mar-Apr;16(2):71-81. PMID: 12746190.

" Xn "UN number: 2811     Class: 6.1     Packing Group: III

Proper shipping name: Toxic solid, organic, n.o.s. (Piroxicam) "

LKT P2859 Phosphate Acceptor Peptide 1 mg 96 PKC and S6 kinase substrate. ≥95% 967.15 C41H74N16O11 Ambient -20°C "O'Brian CA, Ward NE. Stimulation of the ATPase activity of rat brain protein kinase C by phospho acceptor substrates of the enzyme. Biochemistry. 1991 Mar 5;30(9):2549-54. PMID: 1848101.

Chan KF. Ganglioside-modulated protein phosphorylation. Partial purification and characterization of a ganglioside-inhibited protein kinase in brain. J Biol Chem. 1988 Jan 5;263(1):568-74. PMID: 2826449.

O'Brian CA, Lawrence DS, Kaiser ET, et al. Protein kinase C phosphorylates the synthetic peptide Arg-Arg-Lys-Ala-Ser-Gly-Pro-Pro-Val in the presence of phospholipid plus either Ca2+ or a phorbol ester tumor promoter. Biochem Biophys Res Commun. 1984 Oct 15;124(1):296-302. PMID: 6238595.

" Not dangerous goods.

LKT P3269 Piroxicam 10 g 281.8 NSAID; COX-1/2 inhibitor. "4-Hydroxy-2-methyl-N-(2-pyridyl)-2H-1,2-

benzothiazine-3-carboxamide-1,1-dioxide " Feldene; Piroftal; Roxicam 36322-90-4 ≥98% 331.35 C15H13N3O4S CN1C(=C(C2=CC=CC=C2S1(=O)=O)O)C(=O)NC3=CC=CC=N3 Ambient Ambient Insoluble in water. Soluble in acetonitrile. "Chakraborty S, Bose M, Sarkar M. Spectroscopic studies of the binding of Cu(II) complexes of oxicam NSAIDs to alternating G-C and homopolymeric G-C sequences. Spectrochim Acta A Mol Biomol Spectrosc. 2014 Mar 25;122:690-7. PMID: 24345609.

Barkin RL. Topical Nonsteroidal Anti-Inflammatory Drugs: The Importance of Drug, Delivery, and Therapeutic Outcome. Am J Ther. 2012 Feb 22. [Epub ahead of print]. PMID: 22367354.

Tasaki Y, Yamamoto J, Omura T, et al. Oxicam structure in non-steroidal anti-inflammatory drugs is essential to exhibit Akt-mediated neuroprotection against 1-methyl-4-phenyl pyridinium-induced cytotoxicity. Eur J Pharmacol. 2012 Feb 15;676(1-3):57-63. PMID: 22182582.

Qiu ZF, Maruyama K, Sunayama K, et al. Piroxicam-induced regression of intestinal adenomatous polyps in APC(delta474) mice. J Invest Surg. 2003 Mar-Apr;16(2):71-81. PMID: 12746190.

" Xn "UN number: 2811     Class: 6.1     Packing Group: III

Proper shipping name: Toxic solid, organic, n.o.s. (Piroxicam) "

LKT P2859 Phosphate Acceptor Peptide 2 mg 162 PKC and S6 kinase substrate. ≥95% 967.15 C41H74N16O11 Ambient -20°C "O'Brian CA, Ward NE. Stimulation of the ATPase activity of rat brain protein kinase C by phospho acceptor substrates of the enzyme. Biochemistry. 1991 Mar 5;30(9):2549-54. PMID: 1848101.

Chan KF. Ganglioside-modulated protein phosphorylation. Partial purification and characterization of a ganglioside-inhibited protein kinase in brain. J Biol Chem. 1988 Jan 5;263(1):568-74. PMID: 2826449.

O'Brian CA, Lawrence DS, Kaiser ET, et al. Protein kinase C phosphorylates the synthetic peptide Arg-Arg-Lys-Ala-Ser-Gly-Pro-Pro-Val in the presence of phospholipid plus either Ca2+ or a phorbol ester tumor promoter. Biochem Biophys Res Commun. 1984 Oct 15;124(1):296-302. PMID: 6238595.

" Not dangerous goods.

LKT P2859 Phosphate Acceptor Peptide 5 mg 287.9 PKC and S6 kinase substrate. ≥95% 967.15 C41H74N16O11 Ambient -20°C "O'Brian CA, Ward NE. Stimulation of the ATPase activity of rat brain protein kinase C by phospho acceptor substrates of the enzyme. Biochemistry. 1991 Mar 5;30(9):2549-54. PMID: 1848101.

Chan KF. Ganglioside-modulated protein phosphorylation. Partial purification and characterization of a ganglioside-inhibited protein kinase in brain. J Biol Chem. 1988 Jan 5;263(1):568-74. PMID: 2826449.

O'Brian CA, Lawrence DS, Kaiser ET, et al. Protein kinase C phosphorylates the synthetic peptide Arg-Arg-Lys-Ala-Ser-Gly-Pro-Pro-Val in the presence of phospholipid plus either Ca2+ or a phorbol ester tumor promoter. Biochem Biophys Res Commun. 1984 Oct 15;124(1):296-302. PMID: 6238595.

" Not dangerous goods.

LKT P2997 Phytic Acid, 40-50 wt% aqueous solution 100 mL 94.4 Saturated cyclic acid used to store phosphorus in plants. Inositol hexaphosphate; Alkovert; Phytate; myo-Inosistol hexakisphosphate 83-86-3 ≥40% 660.04 C6H18O24P6 C1(C(C(C(C(C1OP(=O)(O)O)OP(=O)(O)O)OP(=O)(O)O)OP(=O)(O)O)OP(=O)(O)O)OP(=O)(O)O Ambient Ambient Soluble in water. "Shafie NH, Esa NM, Ithnin H, et al. Pro-apoptotic effect of rice bran inositol hexaphosphate (IP6) on HT-29 colorectal cancer cells. Int J Mol Sci. 2013 Dec 2;14(12):23545-58. PMID: 24317430.

Lopez-Gonzalez AA, Grases F, Perello J, et al. Phytate levels and bone parameters: a retrospective pilot clinical trial. Front Biosci (Elite Ed). 2010 Jun 1;2:1093-8. PMID: 20515779.

Sudheer Kumar M, Sridhar Reddy B, Kiran Babu S, et al. Antiinflammatory and antiulcer activities of phytic acid in rats. Indian J Exp Biol. 2004 Feb;42(2):179-85. PMID: 15282951.

" Xi "UN number: 3265     Class:  8     Packing group:  II

Proper shipping name:  Corrosive liquid, acidic, organic, n.o.s. (Phytic Acid)

Reportable Quantity (RQ):     Marine Pollutant:  No     Poison Inhalation Hazard:  No"

LKT P2997 Phytic Acid, 40-50 wt% aqueous solution 500 mL 338.8 Saturated cyclic acid used to store phosphorus in plants. Inositol hexaphosphate; Alkovert; Phytate; myo-Inosistol hexakisphosphate 83-86-3 ≥40% 660.04 C6H18O24P6 C1(C(C(C(C(C1OP(=O)(O)O)OP(=O)(O)O)OP(=O)(O)O)OP(=O)(O)O)OP(=O)(O)O)OP(=O)(O)O Ambient Ambient Soluble in water. "Shafie NH, Esa NM, Ithnin H, et al. Pro-apoptotic effect of rice bran inositol hexaphosphate (IP6) on HT-29 colorectal cancer cells. Int J Mol Sci. 2013 Dec 2;14(12):23545-58. PMID: 24317430.

Lopez-Gonzalez AA, Grases F, Perello J, et al. Phytate levels and bone parameters: a retrospective pilot clinical trial. Front Biosci (Elite Ed). 2010 Jun 1;2:1093-8. PMID: 20515779.

Sudheer Kumar M, Sridhar Reddy B, Kiran Babu S, et al. Antiinflammatory and antiulcer activities of phytic acid in rats. Indian J Exp Biol. 2004 Feb;42(2):179-85. PMID: 15282951.

" Xi "UN number: 3265     Class:  8     Packing group:  II

Proper shipping name:  Corrosive liquid, acidic, organic, n.o.s. (Phytic Acid)

Reportable Quantity (RQ):     Marine Pollutant:  No     Poison Inhalation Hazard:  No"

LKT P2918 Phenylethyl-4-methylcaffeate 25 mg 85.4 Derivative of methyl caffeate, hydroxycinnamic acid. ≥98% 298.33 C18H18O4 Ambient 4°C Pereira MA. Prevention of colon cancer and modulation of aberrant crypt foci, cell proliferation, and apoptosis by retinoids and NSAIDs. Adv Exp Med Biol. 1999;470:55-63. PMID: 10709674. Not dangerous goods.

LKT P2918 Phenylethyl-4-methylcaffeate 50 mg 134.9 Derivative of methyl caffeate, hydroxycinnamic acid. ≥98% 298.33 C18H18O4 Ambient 4°C Pereira MA. Prevention of colon cancer and modulation of aberrant crypt foci, cell proliferation, and apoptosis by retinoids and NSAIDs. Adv Exp Med Biol. 1999;470:55-63. PMID: 10709674. Not dangerous goods.

LKT P2918 Phenylethyl-4-methylcaffeate 250 mg 449.6 Derivative of methyl caffeate, hydroxycinnamic acid. ≥98% 298.33 C18H18O4 Ambient 4°C Pereira MA. Prevention of colon cancer and modulation of aberrant crypt foci, cell proliferation, and apoptosis by retinoids and NSAIDs. Adv Exp Med Biol. 1999;470:55-63. PMID: 10709674. Not dangerous goods.

LKT P2919 L-Phenylalaninol 1 g 40.7 Non-essential amino acid alcohol. (S)-2-Amino-3-phenyl-1-propanol S-Phenylalaninol;  β-amino-(S)-(9CI)Benzenepropanol 3182-95-4 ≥98% 151.21 C9H13NO C1=CC=C(C=C1)CC(CO)N Ambient Ambient Soluble in water and methanol. "Landau O, Wasserman L, Deutsch AA, et al.Amino acid alcohols: growth inhibition and induction of differentiated features in melanoma cells. Cancer Lett. 1993 May 14;69(3):203-8. PMID: 8099846.

Hashizume H, Miyamae T, Morikawa T, et al. Effects of phenylalaninol on centrally induced gastric acid secretion. Chem Pharm Bull (Tokyo). 1992 Nov;40(11):3113-4. PMID: 1477931.

Shimomura K, Fukushima T, Danno T, et al. Inhibition of intestinal absorption of phenylalanine by phenylalaninol. J Biochem. 1975 Aug;78(2):269-75. PMID: 1228171.

" C "UN number: 3259     Class: 8     Packing Group: II

Proper shipping name: Amines, solid, corrosive, n.o.s. (L-Phenylalaninol)"

LKT P2919 L-Phenylalaninol 5 g 136 Non-essential amino acid alcohol. (S)-2-Amino-3-phenyl-1-propanol S-Phenylalaninol;  β-amino-(S)-(9CI)Benzenepropanol 3182-95-4 ≥98% 151.21 C9H13NO C1=CC=C(C=C1)CC(CO)N Ambient Ambient Soluble in water and methanol. "Landau O, Wasserman L, Deutsch AA, et al.Amino acid alcohols: growth inhibition and induction of differentiated features in melanoma cells. Cancer Lett. 1993 May 14;69(3):203-8. PMID: 8099846.

Hashizume H, Miyamae T, Morikawa T, et al. Effects of phenylalaninol on centrally induced gastric acid secretion. Chem Pharm Bull (Tokyo). 1992 Nov;40(11):3113-4. PMID: 1477931.

Shimomura K, Fukushima T, Danno T, et al. Inhibition of intestinal absorption of phenylalanine by phenylalaninol. J Biochem. 1975 Aug;78(2):269-75. PMID: 1228171.

" C "UN number: 3259     Class: 8     Packing Group: II

Proper shipping name: Amines, solid, corrosive, n.o.s. (L-Phenylalaninol)"

LKT P2919 L-Phenylalaninol 25 g 407.7 Non-essential amino acid alcohol. (S)-2-Amino-3-phenyl-1-propanol S-Phenylalaninol;  β-amino-(S)-(9CI)Benzenepropanol 3182-95-4 ≥98% 151.21 C9H13NO C1=CC=C(C=C1)CC(CO)N Ambient Ambient Soluble in water and methanol. "Landau O, Wasserman L, Deutsch AA, et al.Amino acid alcohols: growth inhibition and induction of differentiated features in melanoma cells. Cancer Lett. 1993 May 14;69(3):203-8. PMID: 8099846.

Hashizume H, Miyamae T, Morikawa T, et al. Effects of phenylalaninol on centrally induced gastric acid secretion. Chem Pharm Bull (Tokyo). 1992 Nov;40(11):3113-4. PMID: 1477931.

Shimomura K, Fukushima T, Danno T, et al. Inhibition of intestinal absorption of phenylalanine by phenylalaninol. J Biochem. 1975 Aug;78(2):269-75. PMID: 1228171.

" C "UN number: 3259     Class: 8     Packing Group: II

Proper shipping name: Amines, solid, corrosive, n.o.s. (L-Phenylalaninol)"

LKT P2995 Physcion 10 mg 125.9 Anthraquinone found in various plant sources. 1,8-Dihydroxy-3-methoxy-6-methylanthraquinone Parietin; Physcione; Rheochrysidin. 521-61-9 ≥96% 284.26 C16H12O5 CC1=CC(=C2C(=C1)C(=O)C3=CC(=CC(=C3C2=O)O)OC)O ambient 4°C Insoluble in water, slightly soluble in cold alcohol, soluble in boiling alcohol, soluble in benzene, chloroform, ether, acetone, acetic acid, sodium hydroxide and hot sodium carbonate solution, and very slightly soluble in petroleum ether. "Wijesekara I, Zhang C, Van Ta Q, et al. Physcion from marine-derived fungus Microsporum sp. induces apoptosis in human cervical carcinoma HeLa cells. Microbiol Res. 2014 Apr;169(4):255-61. PMID: 24071573.

Locatelli M, Epifano F, Genovese S, et al. Anthraquinone profile, antioxidant and antimicrobial properties of bark extracts of Rhamnus catharticus and R. orbiculatus. Nat Prod Commun. 2011 Sep;6(9):1275-80. PMID: 21941897.

Ghosh S, Das Sarma M, Patra A, et al. Anti-inflammatory and anticancer compounds isolated from Ventilago madraspatana Gaertn., Rubia cordifolia Linn. and Lantana camara Linn. J Pharm Pharmacol. 2010 Sep;62(9):1158-66. PMID: 20796195.

" Xi Not dangerous goods.

LKT P2995 Physcion 25 mg 206 Anthraquinone found in various plant sources. 1,8-Dihydroxy-3-methoxy-6-methylanthraquinone Parietin; Physcione; Rheochrysidin. 521-61-9 ≥96% 284.26 C16H12O5 CC1=CC(=C2C(=C1)C(=O)C3=CC(=CC(=C3C2=O)O)OC)O ambient 4°C Insoluble in water, slightly soluble in cold alcohol, soluble in boiling alcohol, soluble in benzene, chloroform, ether, acetone, acetic acid, sodium hydroxide and hot sodium carbonate solution, and very slightly soluble in petroleum ether. "Wijesekara I, Zhang C, Van Ta Q, et al. Physcion from marine-derived fungus Microsporum sp. induces apoptosis in human cervical carcinoma HeLa cells. Microbiol Res. 2014 Apr;169(4):255-61. PMID: 24071573.

Locatelli M, Epifano F, Genovese S, et al. Anthraquinone profile, antioxidant and antimicrobial properties of bark extracts of Rhamnus catharticus and R. orbiculatus. Nat Prod Commun. 2011 Sep;6(9):1275-80. PMID: 21941897.

Ghosh S, Das Sarma M, Patra A, et al. Anti-inflammatory and anticancer compounds isolated from Ventilago madraspatana Gaertn., Rubia cordifolia Linn. and Lantana camara Linn. J Pharm Pharmacol. 2010 Sep;62(9):1158-66. PMID: 20796195.

" Xi Not dangerous goods.

LKT P2995 Physcion 100 mg 630.1 Anthraquinone found in various plant sources. 1,8-Dihydroxy-3-methoxy-6-methylanthraquinone Parietin; Physcione; Rheochrysidin. 521-61-9 ≥96% 284.26 C16H12O5 CC1=CC(=C2C(=C1)C(=O)C3=CC(=CC(=C3C2=O)O)OC)O ambient 4°C Insoluble in water, slightly soluble in cold alcohol, soluble in boiling alcohol, soluble in benzene, chloroform, ether, acetone, acetic acid, sodium hydroxide and hot sodium carbonate solution, and very slightly soluble in petroleum ether. "Wijesekara I, Zhang C, Van Ta Q, et al. Physcion from marine-derived fungus Microsporum sp. induces apoptosis in human cervical carcinoma HeLa cells. Microbiol Res. 2014 Apr;169(4):255-61. PMID: 24071573.

Locatelli M, Epifano F, Genovese S, et al. Anthraquinone profile, antioxidant and antimicrobial properties of bark extracts of Rhamnus catharticus and R. orbiculatus. Nat Prod Commun. 2011 Sep;6(9):1275-80. PMID: 21941897.

Ghosh S, Das Sarma M, Patra A, et al. Anti-inflammatory and anticancer compounds isolated from Ventilago madraspatana Gaertn., Rubia cordifolia Linn. and Lantana camara Linn. J Pharm Pharmacol. 2010 Sep;62(9):1158-66. PMID: 20796195.

" Xi Not dangerous goods.

LKT P2922 Phenylhexyl Isothiocyanate 100 mg 137.1 ITC found in cruciferous vegetables; HDAC inhibitor. 6-Phenylhexyl isothiocyanate; PHITC 133920-06-6 ≥98% 219.35 C13H17NS C1=CC=C(C=C1)CCCCCCN=C=S Ambient -20°C Soluble in oraganic solvents. "Lu Q, Lin X, Feng J, et al. Phenylhexyl isothiocyanate has dual function as histone deacetylase inhibitor and hypomethylating agent and can inhibit myeloma cell growth by targeting critical pathways. J Hematol Oncol. 2008 Jun 9;1:6. PMID: 18577263.

Lu L, Liu D, Ma X, et al. The phenylhexyl isothiocyanate induces apoptosis and inhibits leukemia cell growth in vivo. Oncol Rep. 2006 Dec;16(6):1363-7. PMID: 17089062.

Morse MA, Eklind KI, Hecht SS, et al. Structure-activity relationships for inhibition of 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone lung tumorigenesis by arylalkyl isothiocyanates in A/J mice. Cancer Res. 1991 Apr 1;51(7):1846-50. PMID: 2004368.

" "UN number: 1760     Class: 8     Packing Group: II

Proper shipping name: Corrosive liquid, n.o.s. (Phenylhexyl isothiocyanate)"

LKT P2994 Physalaemin 1 mg 72.1 Amphibian tachykinin neuropeptide. 2507-24-6 ≥95% 1265.48 C58H84N14O16S1 CC(C)CC(C(=O)NC(CCSC)C(=O)N)NC(=O)CNC(=O)C(CC1=CC=C(C=C1)O)NC(=O)C(CC2=CC=CC=C2)NC(=O)C(CCCCN)NC(=O)C(CC(=O)N)NC(=O)C3CCCN3C(=O)C(CC(=O)O)NC(=O)C(C)NC(=O)C4CCC(=O)N4 Ambient -20°C "Shiina T, Shima T, Hirayama H, et al. Contractile responses induced by physalaemin, an analogue of substance P, in the rat esophagus. Eur J Pharmacol. 2010 Feb 25;628(1-3):202-6. PMID: 19958761.

Fontaine J, Lebrun P. Contractile effects of substance P and other tachykinins on the mouse isolated distal colon. Br J Pharmacol. 1989 Mar;96(3):583-90. PMID: 2470454.

" Not dangerous goods.

LKT P2922 Phenylhexyl Isothiocyanate 250 mg 274.7 ITC found in cruciferous vegetables; HDAC inhibitor. 6-Phenylhexyl isothiocyanate; PHITC 133920-06-6 ≥98% 219.35 C13H17NS C1=CC=C(C=C1)CCCCCCN=C=S Ambient -20°C Soluble in oraganic solvents. "Lu Q, Lin X, Feng J, et al. Phenylhexyl isothiocyanate has dual function as histone deacetylase inhibitor and hypomethylating agent and can inhibit myeloma cell growth by targeting critical pathways. J Hematol Oncol. 2008 Jun 9;1:6. PMID: 18577263.

Lu L, Liu D, Ma X, et al. The phenylhexyl isothiocyanate induces apoptosis and inhibits leukemia cell growth in vivo. Oncol Rep. 2006 Dec;16(6):1363-7. PMID: 17089062.

Morse MA, Eklind KI, Hecht SS, et al. Structure-activity relationships for inhibition of 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone lung tumorigenesis by arylalkyl isothiocyanates in A/J mice. Cancer Res. 1991 Apr 1;51(7):1846-50. PMID: 2004368.

" "UN number: 1760     Class: 8     Packing Group: II

Proper shipping name: Corrosive liquid, n.o.s. (Phenylhexyl isothiocyanate)"

LKT P2922 Phenylhexyl Isothiocyanate 500 mg 412 ITC found in cruciferous vegetables; HDAC inhibitor. 6-Phenylhexyl isothiocyanate; PHITC 133920-06-6 ≥98% 219.35 C13H17NS C1=CC=C(C=C1)CCCCCCN=C=S Ambient -20°C Soluble in oraganic solvents. "Lu Q, Lin X, Feng J, et al. Phenylhexyl isothiocyanate has dual function as histone deacetylase inhibitor and hypomethylating agent and can inhibit myeloma cell growth by targeting critical pathways. J Hematol Oncol. 2008 Jun 9;1:6. PMID: 18577263.

Lu L, Liu D, Ma X, et al. The phenylhexyl isothiocyanate induces apoptosis and inhibits leukemia cell growth in vivo. Oncol Rep. 2006 Dec;16(6):1363-7. PMID: 17089062.

Morse MA, Eklind KI, Hecht SS, et al. Structure-activity relationships for inhibition of 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone lung tumorigenesis by arylalkyl isothiocyanates in A/J mice. Cancer Res. 1991 Apr 1;51(7):1846-50. PMID: 2004368.

" "UN number: 1760     Class: 8     Packing Group: II

Proper shipping name: Corrosive liquid, n.o.s. (Phenylhexyl isothiocyanate)"

LKT P2994 Physalaemin 2 mg 123.1 Amphibian tachykinin neuropeptide. 2507-24-6 ≥95% 1265.48 C58H84N14O16S1 CC(C)CC(C(=O)NC(CCSC)C(=O)N)NC(=O)CNC(=O)C(CC1=CC=C(C=C1)O)NC(=O)C(CC2=CC=CC=C2)NC(=O)C(CCCCN)NC(=O)C(CC(=O)N)NC(=O)C3CCCN3C(=O)C(CC(=O)O)NC(=O)C(C)NC(=O)C4CCC(=O)N4 Ambient -20°C "Shiina T, Shima T, Hirayama H, et al. Contractile responses induced by physalaemin, an analogue of substance P, in the rat esophagus. Eur J Pharmacol. 2010 Feb 25;628(1-3):202-6. PMID: 19958761.

Fontaine J, Lebrun P. Contractile effects of substance P and other tachykinins on the mouse isolated distal colon. Br J Pharmacol. 1989 Mar;96(3):583-90. PMID: 2470454.

" Not dangerous goods.

LKT P2994 Physalaemin 5 mg 216.1 Amphibian tachykinin neuropeptide. 2507-24-6 ≥95% 1265.48 C58H84N14O16S1 CC(C)CC(C(=O)NC(CCSC)C(=O)N)NC(=O)CNC(=O)C(CC1=CC=C(C=C1)O)NC(=O)C(CC2=CC=CC=C2)NC(=O)C(CCCCN)NC(=O)C(CC(=O)N)NC(=O)C3CCCN3C(=O)C(CC(=O)O)NC(=O)C(C)NC(=O)C4CCC(=O)N4 Ambient -20°C "Shiina T, Shima T, Hirayama H, et al. Contractile responses induced by physalaemin, an analogue of substance P, in the rat esophagus. Eur J Pharmacol. 2010 Feb 25;628(1-3):202-6. PMID: 19958761.

Fontaine J, Lebrun P. Contractile effects of substance P and other tachykinins on the mouse isolated distal colon. Br J Pharmacol. 1989 Mar;96(3):583-90. PMID: 2470454.

" Not dangerous goods.

LKT P2993 Phyllomedusin 1 mg 132 Amphibian tachykinin neuropeptide; NK1 activator. 26145-48-2 ≥95% 1171.41 C52H82N16O13S1 CCC(C)C(C(=O)NCC(=O)NC(CC(C)C)C(=O)NC(CCSC)C(=O)N)NC(=O)C(CC1=CC=CC=C1)NC(=O)C(CCCN=C(N)N)NC(=O)C(CC(=O)N)NC(=O)C2CCCN2C(=O)C(CC(=O)N)NC(=O)C3CCC(=O)N3 Ambient -20°C "Ganjiwale AD, Cowsik SM. Three-dimensional structure of Phyllomedusin, a NK1 receptor agonist bound to dodecylphosphocholine micelles. J Struct Biol. 2009 Aug;167(2):176-84. PMID: 19409496.

Bertaccini G, Coruzzi G. Action of some natural peptides on the stomach of the anaesthetized rat. Naunyn Schmiedebergs Arch Pharmacol. 1977 Jun;298(2):163-6. PMID: 882154.

Széli J, Molina E, Zappia L, et al. Action of some natural polypeptides on the longitudinal muscle of the guinea pig ileum. Eur J Pharmacol. 1977 Jun 1;43(3):285-7. PMID: 872882.

"

LKT P2993 Phyllomedusin 2 mg 225 Amphibian tachykinin neuropeptide; NK1 activator. 26145-48-2 ≥95% 1171.41 C52H82N16O13S1 CCC(C)C(C(=O)NCC(=O)NC(CC(C)C)C(=O)NC(CCSC)C(=O)N)NC(=O)C(CC1=CC=CC=C1)NC(=O)C(CCCN=C(N)N)NC(=O)C(CC(=O)N)NC(=O)C2CCCN2C(=O)C(CC(=O)N)NC(=O)C3CCC(=O)N3 Ambient -20°C "Ganjiwale AD, Cowsik SM. Three-dimensional structure of Phyllomedusin, a NK1 receptor agonist bound to dodecylphosphocholine micelles. J Struct Biol. 2009 Aug;167(2):176-84. PMID: 19409496.

Bertaccini G, Coruzzi G. Action of some natural peptides on the stomach of the anaesthetized rat. Naunyn Schmiedebergs Arch Pharmacol. 1977 Jun;298(2):163-6. PMID: 882154.

Széli J, Molina E, Zappia L, et al. Action of some natural polypeptides on the longitudinal muscle of the guinea pig ileum. Eur J Pharmacol. 1977 Jun 1;43(3):285-7. PMID: 872882.

"

LKT P2993 Phyllomedusin 5 mg 396.1 Amphibian tachykinin neuropeptide; NK1 activator. 26145-48-2 ≥95% 1171.41 C52H82N16O13S1 CCC(C)C(C(=O)NCC(=O)NC(CC(C)C)C(=O)NC(CCSC)C(=O)N)NC(=O)C(CC1=CC=CC=C1)NC(=O)C(CCCN=C(N)N)NC(=O)C(CC(=O)N)NC(=O)C2CCCN2C(=O)C(CC(=O)N)NC(=O)C3CCC(=O)N3 Ambient -20°C "Ganjiwale AD, Cowsik SM. Three-dimensional structure of Phyllomedusin, a NK1 receptor agonist bound to dodecylphosphocholine micelles. J Struct Biol. 2009 Aug;167(2):176-84. PMID: 19409496.

Bertaccini G, Coruzzi G. Action of some natural peptides on the stomach of the anaesthetized rat. Naunyn Schmiedebergs Arch Pharmacol. 1977 Jun;298(2):163-6. PMID: 882154.

Széli J, Molina E, Zappia L, et al. Action of some natural polypeptides on the longitudinal muscle of the guinea pig ileum. Eur J Pharmacol. 1977 Jun 1;43(3):285-7. PMID: 872882.

"

LKT P2992 Phyllolitorin 0.5 mg 72.1 Peptide found in amphibian skin; GRP (BB1) and neuromedin B (BB2) agonist. 87734-77-8 ≥95% 1020.24 C49H69N11O11S1 CC(C)CC(C(=O)NC(CC1=CNC2=CC=CC=C21)C(=O)NC(C)C(=O)NC(C(C)C)C(=O)NCC(=O)NC(CO)C(=O)NC(CC3=CC=CC=C3)C(=O)NC(CCSC)C(=O)N)NC(=O)C4CCC(=O)N4 Ambient -20°C "Lin JT, Coy DH, Mantey SA, et al. Comparison of the peptide structural requirements for high affinity interaction with bombesin receptors. Eur J Pharmacol. 1995 Dec 27;294(1):55-69. PMID: 8788416.

King KA, Torday JS, Sunday ME. Bombesin and [Leu8]phyllolitorin promote fetal mouse lung branching morphogenesis via a receptor-mediated mechanism. Proc Natl Acad Sci U S A. 1995 May 9;92(10):4357-61. PMID: 7753811.

Masui A, Kato N, Itoshima T, et al. Scratching behavior induced by bombesin-related peptides. Comparison of bombesin, gastrin-releasing peptide and phyllolitorins. Eur J Pharmacol. 1993 Jul 20;238(2-3):297-301. PMID: 7691621.

Falconieri Erspamer G, Mazzanti G, Farruggia G, et al. Parallel bioassay of litorin and phyllolitorins on smooth muscle preparations. Peptides. 1984 Jul-Aug;5(4):765-8. PMID: 6494026.

"

LKT P2992 Phyllolitorin 1 mg 123.1 Peptide found in amphibian skin; GRP (BB1) and neuromedin B (BB2) agonist. 87734-77-8 ≥95% 1020.24 C49H69N11O11S1 CC(C)CC(C(=O)NC(CC1=CNC2=CC=CC=C21)C(=O)NC(C)C(=O)NC(C(C)C)C(=O)NCC(=O)NC(CO)C(=O)NC(CC3=CC=CC=C3)C(=O)NC(CCSC)C(=O)N)NC(=O)C4CCC(=O)N4 Ambient -20°C "Lin JT, Coy DH, Mantey SA, et al. Comparison of the peptide structural requirements for high affinity interaction with bombesin receptors. Eur J Pharmacol. 1995 Dec 27;294(1):55-69. PMID: 8788416.

King KA, Torday JS, Sunday ME. Bombesin and [Leu8]phyllolitorin promote fetal mouse lung branching morphogenesis via a receptor-mediated mechanism. Proc Natl Acad Sci U S A. 1995 May 9;92(10):4357-61. PMID: 7753811.

Masui A, Kato N, Itoshima T, et al. Scratching behavior induced by bombesin-related peptides. Comparison of bombesin, gastrin-releasing peptide and phyllolitorins. Eur J Pharmacol. 1993 Jul 20;238(2-3):297-301. PMID: 7691621.

Falconieri Erspamer G, Mazzanti G, Farruggia G, et al. Parallel bioassay of litorin and phyllolitorins on smooth muscle preparations. Peptides. 1984 Jul-Aug;5(4):765-8. PMID: 6494026.

"

LKT P2992 Phyllolitorin 2.5 mg 216.1 Peptide found in amphibian skin; GRP (BB1) and neuromedin B (BB2) agonist. 87734-77-8 ≥95% 1020.24 C49H69N11O11S1 CC(C)CC(C(=O)NC(CC1=CNC2=CC=CC=C21)C(=O)NC(C)C(=O)NC(C(C)C)C(=O)NCC(=O)NC(CO)C(=O)NC(CC3=CC=CC=C3)C(=O)NC(CCSC)C(=O)N)NC(=O)C4CCC(=O)N4 Ambient -20°C "Lin JT, Coy DH, Mantey SA, et al. Comparison of the peptide structural requirements for high affinity interaction with bombesin receptors. Eur J Pharmacol. 1995 Dec 27;294(1):55-69. PMID: 8788416.

King KA, Torday JS, Sunday ME. Bombesin and [Leu8]phyllolitorin promote fetal mouse lung branching morphogenesis via a receptor-mediated mechanism. Proc Natl Acad Sci U S A. 1995 May 9;92(10):4357-61. PMID: 7753811.

Masui A, Kato N, Itoshima T, et al. Scratching behavior induced by bombesin-related peptides. Comparison of bombesin, gastrin-releasing peptide and phyllolitorins. Eur J Pharmacol. 1993 Jul 20;238(2-3):297-301. PMID: 7691621.

Falconieri Erspamer G, Mazzanti G, Farruggia G, et al. Parallel bioassay of litorin and phyllolitorins on smooth muscle preparations. Peptides. 1984 Jul-Aug;5(4):765-8. PMID: 6494026.

"

LKT AP100 Plate Apoptosis 1 kit 204.3 Dry Ice -80°C

LKT AP101 Apoptosis 1 kit 243.8 Dry Ice -80°C

LKT AP102 Apoptosis 1 kit 166.8 Dry Ice -80°C

LKT AP103 Apoptosis 1 kit 153.8 Dry Ice -80°C

LKT AP104 Apoptosis 1 kit 142.5 Dry Ice -80°C

LKT AP105 Apoptosis 1 kit 320.7 Dry Ice -80°C

LKT AP106 Apoptosis 1 kit 277.6 Dry Ice -80°C

LKT AP107 Apoptosis 1 kit 142.5 Dry Ice -80°C

LKT AP108 Apoptosis 1 kit 305.9 Dry Ice -80°C

LKT AP109 Apoptosis 1 kit 305.9 Dry Ice -80°C

LKT AP110 Apoptosis 1 kit 208.1 Dry Ice -80°C

LKT AP111 Apoptosis 1 kit 382.5 Dry Ice -80°C

LKT AP112 Apoptosis 1 kit 255 Dry Ice -80°C

LKT AP113 Apoptosis 1 kit 785.8 Dry Ice -80°C

LKT AP114 Apoptosis 1 kit 485.7 Dry Ice -80°C

LKT AP115 Apoptosis 1 kit 208.1 Dry Ice -80°C

LKT AP116 Apoptosis 1 kit 197 Dry Ice -80°C

LKT AP117 Apoptosis 1 kit 277.6 Dry Ice -80°C

LKT AP118 Apoptosis 1 kit 221.2 Dry Ice -80°C

LKT AA100 Antiangiogenesis 1 kit 193.1 Dry Ice -80°C

LKT AA101 Antiangiogenesis 1 kit 142.5 Dry Ice -80°C

LKT AA102 Antiangiogenesis 1 kit 177.8 Dry Ice -80°C

LKT AA103 Antiangiogenesis 1 kit 142.5 Dry Ice -80°C

LKT AA104 Antiangiogenesis 1 kit 142.5 Dry Ice -80°C

LKT AA105 Antiangiogenesis 1 kit 193.1 Dry Ice -80°C

LKT AA106 Antiangiogenesis 1 kit 193.1 Dry Ice -80°C

LKT AA107 Antiangiogenesis 1 kit 197 Dry Ice -80°C

LKT AA108 Antiangiogenesis 1 kit 393.8 Dry Ice -80°C

LKT AA109 Antiangiogenesis 1 kit 474.5 Dry Ice -80°C

LKT AA110 Antiangiogenesis 1 kit 682.6 Dry Ice -80°C

LKT CP100 Chemoprevention 1 kit 148.4 Dry Ice -80°C

LKT CP101 Chemoprevention 1 kit 138.1 Dry Ice -80°C

LKT CP102 Chemoprevention 1 kit 138.1 Dry Ice -80°C

LKT CP103 Chemoprevention 1 kit 138.1 Dry Ice -80°C

LKT CP106 Chemoprevention 1 kit 125.6 Dry Ice -80°C

LKT CP105 Chemoprevention 1 kit 125.6 Dry Ice -80°C

LKT CP110 Chemoprevention 1 kit 138.1 Dry Ice -80°C

LKT CP111 Chemoprevention 1 kit 138.1 Dry Ice -80°C

LKT CP112 Chemoprevention 1 kit 138.1 Dry Ice -80°C

LKT CP113 Chemoprevention 1 kit 138.1 Dry Ice -80°C

LKT CP114 Chemoprevention 1 kit 204.3 Dry Ice -80°C

LKT CP115 Chemoprevention 1 kit 157.5 Dry Ice -80°C

LKT CP116 Chemoprevention 1 kit 181.4 Dry Ice -80°C

LKT CP107 Chemoprevention 1 kit 138.1 Dry Ice -80°C

LKT CP108 Chemoprevention 1 kit 138.1 Dry Ice -80°C

LKT CP109 Chemoprevention 1 kit 125.8 Dry Ice -80°C

LKT CP120 Chemopreventive 1 kit 148.4 Dry Ice -80°C

LKT CP121 Chemopreventive 1 kit 158.8 Dry Ice -80°C

LKT CP122 Chemopreventive 1 kit 125.6 Dry Ice -80°C

LKT CP123 Chemopreventive 1 kit 181.4 Dry Ice -80°C

LKT CP124 Chemopreventive 1 kit 138.1 Dry Ice -80°C

LKT CP125 Chemopreventive 1 kit 158.8 Dry Ice -80°C

LKT CP126 Chemopreventive 1 kit 148.4 Dry Ice -80°C

LKT CP127 Chemopreventive 1 kit 135 Dry Ice -80°C

LKT CP128 Chemopreventive 1 kit 125.6 Dry Ice -80°C

LKT CP129 Chemopreventive 1 kit 181.4 Dry Ice -80°C

LKT CP130 Chemopreventive 1 kit 158.8 Dry Ice -80°C

LKT CP131 Chemopreventive 1 kit 148.4 Dry Ice -80°C

LKT CP132 Chemopreventive 1 kit 181.4 Dry Ice -80°C

LKT CP133 Chemopreventive 1 kit 148.4 Dry Ice -80°C

LKT CP134 Chemopreventive 1 kit 148.4 Dry Ice -80°C

LKT CP135 Chemopreventive 1 kit 148.4 Dry Ice -80°C

LKT CP136 Chemopreventive 1 kit 148.4 Dry Ice -80°C

LKT CP137 Chemopreventive 1 kit 148.4 Dry Ice -80°C

LKT CP138 Chemopreventive 1 kit 171.3 Dry Ice -80°C

LKT CP139 Chemopreventive 1 kit 241.2 Dry Ice -80°C

LKT CP140 Chemopreventive 1 kit 138.1 Dry Ice -80°C

LKT CP141 Chemopreventive 1 kit 138.1 Dry Ice -80°C

LKT CP142 Chemopreventive 1 kit 125.8 Dry Ice -80°C

LKT CP143 Chemopreventive 1 kit 175.4 Dry Ice -80°C

LKT CP144 Chemopreventive 1 kit 1330.5 Dry Ice -80°C

LKT CP145 Chemopreventive 1 kit 195.9 Dry Ice -80°C

LKT CP146 Chemopreventive 1 kit 175.4 Dry Ice -80°C

LKT CP147 Chemopreventive 1 kit 195.9 Dry Ice -80°C

LKT CP148 Chemopreventive 1 kit 175.4 Dry Ice -80°C

LKT CP149 Chemopreventive 1 kit 165.1 Dry Ice -80°C

LKT CP150 Chemopreventive 1 kit 165.1 Dry Ice -80°C

LKT CP151 Chemopreventive 1 kit 185.6 Dry Ice -80°C

LKT T2936 Thioridazine Hydrochloride 5 g 83.7 Piperadine phenothiazine; FIASMA, D1-5, histamine H1/2, M1-5 mAChR, 5-HT1/2/5/6/7, α1/2-adrenergic antagonist, NET inhibitor, hERG K+ channel inhibitor. 130-61-0 ≥98% 407.04 C21H26N2S2 HCl CN1CCCCC1CCN2C3=CC=CC=C3SC4=C2C=C(C=C4)SC.Cl Ambient Ambient "Thorsing M, Klitgaard JK, Atilano ML, et al. Thioridazine induces major changes in global gene expression and cell wall composition in methicillin-resistant Staphylococcus aureus USA300. PLoS One. 2013 May 17;8(5):e64518. PMID: 23691239.

Byun HJ, Lee JH, Kim BR, et al. Anti-angiogenic effects of thioridazine involving the FAK-mTOR pathway. Microvasc Res. 2012 Nov;84(3):227-34. PMID: 23022044.

Kang S, Dong SM, Kim BR, et al. Thioridazine induces apoptosis by targeting the PI3K/Akt/mTOR pathway in cervical and endometrial cancer cells. Apoptosis. 2012 Sep;17(9):989-97. PMID: 22460505.

Roth BL, Driscol J. PDSP Ki Database. Psychoactive Drug Screening Program (PDSP). University of North Carolina at Chapel Hill and the United States National Institute of Mental Health. 2011 Jan.

van Soolingen D, Hernandez-Pando R, Orozco H, et al. The antipsychotic thioridazine shows promising therapeutic activity in a mouse model of multidrug-resistant tuberculosis. PLoS One. 2010 Sep 9;5(9). pii: e12640. PMID: 20844587.

Dutta NK, Mehra S, Kaushal D. A Mycobacterium tuberculosis sigma factor network responds to cell-envelope damage by the promising anti-mycobacterial thioridazine. PLoS One. 2010 Apr 8;5(4):e10069. PMID: 20386700.

Crumb WJ Jr, Ekins S, Sarazan RD, et al. Effects of antipsychotic drugs on I(to), I (Na), I (sus), I (K1), and hERG: QT prolongation, structure activity relationship, and network analysis. Pharm Res. 2006 Jun;23(6):1133-43. PMID: 16715368.

" Xn, N Not dangerous goods.

LKT T2936 Thioridazine Hydrochloride 25 g 335 Piperadine phenothiazine; FIASMA, D1-5, histamine H1/2, M1-5 mAChR, 5-HT1/2/5/6/7, α1/2-adrenergic antagonist, NET inhibitor, hERG K+ channel inhibitor. 130-61-0 ≥98% 407.04 C21H26N2S2 HCl CN1CCCCC1CCN2C3=CC=CC=C3SC4=C2C=C(C=C4)SC.Cl Ambient Ambient "Thorsing M, Klitgaard JK, Atilano ML, et al. Thioridazine induces major changes in global gene expression and cell wall composition in methicillin-resistant Staphylococcus aureus USA300. PLoS One. 2013 May 17;8(5):e64518. PMID: 23691239.

Byun HJ, Lee JH, Kim BR, et al. Anti-angiogenic effects of thioridazine involving the FAK-mTOR pathway. Microvasc Res. 2012 Nov;84(3):227-34. PMID: 23022044.

Kang S, Dong SM, Kim BR, et al. Thioridazine induces apoptosis by targeting the PI3K/Akt/mTOR pathway in cervical and endometrial cancer cells. Apoptosis. 2012 Sep;17(9):989-97. PMID: 22460505.

Roth BL, Driscol J. PDSP Ki Database. Psychoactive Drug Screening Program (PDSP). University of North Carolina at Chapel Hill and the United States National Institute of Mental Health. 2011 Jan.

van Soolingen D, Hernandez-Pando R, Orozco H, et al. The antipsychotic thioridazine shows promising therapeutic activity in a mouse model of multidrug-resistant tuberculosis. PLoS One. 2010 Sep 9;5(9). pii: e12640. PMID: 20844587.

Dutta NK, Mehra S, Kaushal D. A Mycobacterium tuberculosis sigma factor network responds to cell-envelope damage by the promising anti-mycobacterial thioridazine. PLoS One. 2010 Apr 8;5(4):e10069. PMID: 20386700.

Crumb WJ Jr, Ekins S, Sarazan RD, et al. Effects of antipsychotic drugs on I(to), I (Na), I (sus), I (K1), and hERG: QT prolongation, structure activity relationship, and network analysis. Pharm Res. 2006 Jun;23(6):1133-43. PMID: 16715368.

" Xn, N Not dangerous goods.

LKT R0248 Ramatroban 10 mg 176.6 CRTH2 inhibitor, TxA2 antagonist. 116649-85-5 ≥98% 416.47 C21H21FN2O4S C1CC2=C(CC1NS(=O)(=O)C3=CC=C(C=C3)F)C4=CC=CC=C4N2CCC(=O)O Ambient Ambient "Suzuki Y, Inoue T, Yamamoto A, et al. Prophylactic effects of the histamine H1 receptor antagonist epinastine and the dual thromboxane A2 receptor and chemoattractant receptor-homologous molecule expressed on Th2 cells antagonist ramatroban on allergic rhinitis model in mice. Biol Pharm Bull. 2011;34(4):507-10. PMID: 21467637.

Akiyama K, Karaki M, Kobayshi R, et al. IL-16 variability and modulation by antiallergic drugs in a murine experimental allergic rhinitis model. Int Arch Allergy Immunol. 2009;149(4):315-22. PMID: 19295235.

Sugimoto H, Shichijo M, Okano M, et al. CRTH2-specific binding characteristics of [3H]ramatroban and its effects on PGD2-, 15-deoxy-Delta12, 14-PGJ2- and indomethacin-induced agonist responses. Eur J Pharmacol. 2005 Nov 7;524(1-3):30-7. PMID: 16256979.

Shiraishi Y, Asano K, Nakajima T, et al. Prostaglandin D2-induced eosinophilic airway inflammation is mediated by CRTH2 receptor. J Pharmacol Exp Ther. 2005 Mar;312(3):954-60. PMID: 15528449.

Ishizuka T, Matsui T, Okamoto Y, et al. Ramatroban (BAY u 3405): a novel dual antagonist of TXA2 receptor and CRTh2, a newly identified prostaglandin D2 receptor. Cardiovasc Drug Rev. 2004 Summer;22(2):71-90. PMID: 15179446.

" Xi Not dangerous goods.

LKT R0248 Ramatroban 25 mg 421.4 CRTH2 inhibitor, TxA2 antagonist. 116649-85-5 ≥98% 416.47 C21H21FN2O4S C1CC2=C(CC1NS(=O)(=O)C3=CC=C(C=C3)F)C4=CC=CC=C4N2CCC(=O)O Ambient Ambient "Suzuki Y, Inoue T, Yamamoto A, et al. Prophylactic effects of the histamine H1 receptor antagonist epinastine and the dual thromboxane A2 receptor and chemoattractant receptor-homologous molecule expressed on Th2 cells antagonist ramatroban on allergic rhinitis model in mice. Biol Pharm Bull. 2011;34(4):507-10. PMID: 21467637.

Akiyama K, Karaki M, Kobayshi R, et al. IL-16 variability and modulation by antiallergic drugs in a murine experimental allergic rhinitis model. Int Arch Allergy Immunol. 2009;149(4):315-22. PMID: 19295235.

Sugimoto H, Shichijo M, Okano M, et al. CRTH2-specific binding characteristics of [3H]ramatroban and its effects on PGD2-, 15-deoxy-Delta12, 14-PGJ2- and indomethacin-induced agonist responses. Eur J Pharmacol. 2005 Nov 7;524(1-3):30-7. PMID: 16256979.

Shiraishi Y, Asano K, Nakajima T, et al. Prostaglandin D2-induced eosinophilic airway inflammation is mediated by CRTH2 receptor. J Pharmacol Exp Ther. 2005 Mar;312(3):954-60. PMID: 15528449.

Ishizuka T, Matsui T, Okamoto Y, et al. Ramatroban (BAY u 3405): a novel dual antagonist of TXA2 receptor and CRTh2, a newly identified prostaglandin D2 receptor. Cardiovasc Drug Rev. 2004 Summer;22(2):71-90. PMID: 15179446.

" Xi Not dangerous goods.

LKT R0248 Ramatroban 100 mg 1223 CRTH2 inhibitor, TxA2 antagonist. 116649-85-5 ≥98% 416.47 C21H21FN2O4S C1CC2=C(CC1NS(=O)(=O)C3=CC=C(C=C3)F)C4=CC=CC=C4N2CCC(=O)O Ambient Ambient "Suzuki Y, Inoue T, Yamamoto A, et al. Prophylactic effects of the histamine H1 receptor antagonist epinastine and the dual thromboxane A2 receptor and chemoattractant receptor-homologous molecule expressed on Th2 cells antagonist ramatroban on allergic rhinitis model in mice. Biol Pharm Bull. 2011;34(4):507-10. PMID: 21467637.

Akiyama K, Karaki M, Kobayshi R, et al. IL-16 variability and modulation by antiallergic drugs in a murine experimental allergic rhinitis model. Int Arch Allergy Immunol. 2009;149(4):315-22. PMID: 19295235.

Sugimoto H, Shichijo M, Okano M, et al. CRTH2-specific binding characteristics of [3H]ramatroban and its effects on PGD2-, 15-deoxy-Delta12, 14-PGJ2- and indomethacin-induced agonist responses. Eur J Pharmacol. 2005 Nov 7;524(1-3):30-7. PMID: 16256979.

Shiraishi Y, Asano K, Nakajima T, et al. Prostaglandin D2-induced eosinophilic airway inflammation is mediated by CRTH2 receptor. J Pharmacol Exp Ther. 2005 Mar;312(3):954-60. PMID: 15528449.

Ishizuka T, Matsui T, Okamoto Y, et al. Ramatroban (BAY u 3405): a novel dual antagonist of TXA2 receptor and CRTh2, a newly identified prostaglandin D2 receptor. Cardiovasc Drug Rev. 2004 Summer;22(2):71-90. PMID: 15179446.

" Xi Not dangerous goods.

LKT D0262 Dapiprazole Hydrochloride 10 mg 63.7 α1-Adrenergic antagonist. 72822-13-0 ≥98% 357.89 C19H23N5 HCl CC1=CC=CC=C1N2CCN(CC2)CCC3=NN=C4N3CCCC4.Cl Ambient Ambient "Eltze M. Affinity of the miotic drug, dapiprazole, at alpha 1-adrenoceptor subtypes A, B and D. J Pharm Pharmacol. 1997 Nov;49(11):1091-5. PMID: 9401944.

Hogan TS, McDaniel DD, Bartlett JD, et al. Dose-response study of dapiprazole HCl in the reversal of mydriasis induced by 2.5% phenylephrine. J Ocul Pharmacol Ther. 1997 Aug;13(4):297-302. PMID: 9261765.

Mastropasqua L, Carpineto P, Ciancaglini M, et al. The usefulness of dapiprazole, an alpha-adrenergic blocking agent, in pigmentary glaucoma. Ophthalmic Surg Lasers. 1996 Sep;27(9):806-9. PMID: 8878205.

Mastropasqua L, Carpineto P, Ciancaglini M, et al. Effect of dapiprazole, an alpha-adrenergic blocking agent, on aqueous humor dynamics in pigmentary glaucoma. Ophthalmic Res. 1996;28(5):312-8. PMID: 8979280.

Nyman N, Reich L. The effect of dapiprazole on accommodative amplitude in eyes dilated with 0.5 percent tropicamide. J Am Optom Assoc. 1993 Sep;64(9):625-8. PMID: 7901257.

" Not dangerous goods.

LKT D0262 Dapiprazole Hydrochloride 25 mg 142.4 α1-Adrenergic antagonist. 72822-13-0 ≥98% 357.89 C19H23N5 HCl CC1=CC=CC=C1N2CCN(CC2)CCC3=NN=C4N3CCCC4.Cl Ambient Ambient "Eltze M. Affinity of the miotic drug, dapiprazole, at alpha 1-adrenoceptor subtypes A, B and D. J Pharm Pharmacol. 1997 Nov;49(11):1091-5. PMID: 9401944.

Hogan TS, McDaniel DD, Bartlett JD, et al. Dose-response study of dapiprazole HCl in the reversal of mydriasis induced by 2.5% phenylephrine. J Ocul Pharmacol Ther. 1997 Aug;13(4):297-302. PMID: 9261765.

Mastropasqua L, Carpineto P, Ciancaglini M, et al. The usefulness of dapiprazole, an alpha-adrenergic blocking agent, in pigmentary glaucoma. Ophthalmic Surg Lasers. 1996 Sep;27(9):806-9. PMID: 8878205.

Mastropasqua L, Carpineto P, Ciancaglini M, et al. Effect of dapiprazole, an alpha-adrenergic blocking agent, on aqueous humor dynamics in pigmentary glaucoma. Ophthalmic Res. 1996;28(5):312-8. PMID: 8979280.

Nyman N, Reich L. The effect of dapiprazole on accommodative amplitude in eyes dilated with 0.5 percent tropicamide. J Am Optom Assoc. 1993 Sep;64(9):625-8. PMID: 7901257.

" Not dangerous goods.

LKT D0262 Dapiprazole Hydrochloride 100 mg 468.8 α1-Adrenergic antagonist. 72822-13-0 ≥98% 357.89 C19H23N5 HCl CC1=CC=CC=C1N2CCN(CC2)CCC3=NN=C4N3CCCC4.Cl Ambient Ambient "Eltze M. Affinity of the miotic drug, dapiprazole, at alpha 1-adrenoceptor subtypes A, B and D. J Pharm Pharmacol. 1997 Nov;49(11):1091-5. PMID: 9401944.

Hogan TS, McDaniel DD, Bartlett JD, et al. Dose-response study of dapiprazole HCl in the reversal of mydriasis induced by 2.5% phenylephrine. J Ocul Pharmacol Ther. 1997 Aug;13(4):297-302. PMID: 9261765.

Mastropasqua L, Carpineto P, Ciancaglini M, et al. The usefulness of dapiprazole, an alpha-adrenergic blocking agent, in pigmentary glaucoma. Ophthalmic Surg Lasers. 1996 Sep;27(9):806-9. PMID: 8878205.

Mastropasqua L, Carpineto P, Ciancaglini M, et al. Effect of dapiprazole, an alpha-adrenergic blocking agent, on aqueous humor dynamics in pigmentary glaucoma. Ophthalmic Res. 1996;28(5):312-8. PMID: 8979280.

Nyman N, Reich L. The effect of dapiprazole on accommodative amplitude in eyes dilated with 0.5 percent tropicamide. J Am Optom Assoc. 1993 Sep;64(9):625-8. PMID: 7901257.

" Not dangerous goods.

LKT C1624 Cefuroxime Sodium 1 g 80.4 β-lactam; penicillin binding protein inhibitor. Monosodium (6R, 7R)-3-carbamoyloxymethyl-7-[(Z)-2-furan-2-yl-2-methoxyiminoacetylamino]-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2carboxylate 56238-63-2 ≥98% 446.37 C16H15N4NaO8S CON=C(C1=CC=CO1)C(=O)NC2C3N(C2=O)C(=C(CS3)COC(=O)N)C(=O)[O-].[Na+] Ambient Ambient Water, methanol "Mor F, Cohen IR. Beta-lactam antibiotics modulate T-cell functions and gene expression via covalent binding to cellular albumin. Proc Natl Acad Sci U S A. 2013 Feb 19;110(8):2981-6. PMID: 23382225.

Abdullah FE, Mushtaq A, Irshad M, et al. Current efficacy of antibiotics against Klebsiella isolates from urine samples - a multi-centric experience in Karachi. Pak J Pharm Sci. 2013 Jan;26(1):11-5. PMID: 23261722.

Sykes RB, Griffiths A, Ryan DM. Comparative acitivity of ampicillin and cefuroxime against three types of Haemophilus influenzae. Antimicrob Agents Chemother. 1977 Apr;11(4):599-604. PMID: 301007.

Eykyn S, Jenkins C, King A, et al. Antibacterial activity of cefuroxime, a new cephalosporin antibiotic, compared with that of cephaloridine, cephalothin, and cefamandole. Antimicrob Agents Chemother. 1976 Apr;9(4):690-5. PMID: 1267441.

" Xn Not dangerous goods.

LKT C1624 Cefuroxime Sodium 5 g 268 β-lactam; penicillin binding protein inhibitor. Monosodium (6R, 7R)-3-carbamoyloxymethyl-7-[(Z)-2-furan-2-yl-2-methoxyiminoacetylamino]-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2carboxylate 56238-63-2 ≥98% 446.37 C16H15N4NaO8S CON=C(C1=CC=CO1)C(=O)NC2C3N(C2=O)C(=C(CS3)COC(=O)N)C(=O)[O-].[Na+] Ambient Ambient Water, methanol "Mor F, Cohen IR. Beta-lactam antibiotics modulate T-cell functions and gene expression via covalent binding to cellular albumin. Proc Natl Acad Sci U S A. 2013 Feb 19;110(8):2981-6. PMID: 23382225.

Abdullah FE, Mushtaq A, Irshad M, et al. Current efficacy of antibiotics against Klebsiella isolates from urine samples - a multi-centric experience in Karachi. Pak J Pharm Sci. 2013 Jan;26(1):11-5. PMID: 23261722.

Sykes RB, Griffiths A, Ryan DM. Comparative acitivity of ampicillin and cefuroxime against three types of Haemophilus influenzae. Antimicrob Agents Chemother. 1977 Apr;11(4):599-604. PMID: 301007.

Eykyn S, Jenkins C, King A, et al. Antibacterial activity of cefuroxime, a new cephalosporin antibiotic, compared with that of cephaloridine, cephalothin, and cefamandole. Antimicrob Agents Chemother. 1976 Apr;9(4):690-5. PMID: 1267441.

" Xn Not dangerous goods.

LKT N3378 S-Nitrosoglutathione 5 mg 94 NO donor. 57564-91-7 ≥98% 336.32 C10H16N4O7S C(CC(=O)NC(CSN=O)C(=O)NCC(=O)O)C(C(=O)O)N Ambient -20°C "Lohman AW, Weaver JL, Billaud M, et al. S-nitrosylation inhibits pannexin 1 channel function. J Biol Chem. 2012 Nov 16;287(47):39602-12. PMID: 23033481.

Servetnyk Z, Krjukova J, Gaston B, et al. Activation of chloride transport in CF airway epithelial cell lines and primary CF nasal epithelial cells by S-nitrosoglutathione. Respir Res. 2006 Oct 5;7:124. PMID: 17022806.

Carvalho-Filho MA, Ueno M, Hirabara SM, et al. S-nitrosation of the insulin receptor, insulin receptor substrate 1, and protein kinase B/Akt: a novel mechanism of insulin resistance. Diabetes. 2005 Apr;54(4):959-67. PMID: 15793233.

Jeon HK, Choi SU, Jung NP. Association of the ERK1/2 and p38 kinase pathways with nitric oxide-induced apoptosis and cell cycle arrest in colon cancer cells. Cell Biol Toxicol. 2005 Mar;21(2):115-25. PMID: 16142585.

Ciriolo MR, Aquilano K, De Martino A, et al. Differential role of superoxide and glutathione in S-nitrosoglutathione-mediated apoptosis: a rationale for mild forms of familial amyotrophic lateral sclerosis associated with less active Cu,Zn superoxide dismutase mutants. J Neurochem. 2001 Jun;77(6):1433-43. PMID: 11413228.

Dalle-Donne I, Milzani A, Giustarini D, et al. S-NO-actin: S-nitrosylation kinetics and the effect on isolated vascular smooth muscle. J Muscle Res Cell Motil. 2000 Feb;21(2):171-81. PMID: 10961840.

Messmer UK, Brüne B. Nitric oxide-induced apoptosis: p53-dependent and p53-independent signalling pathways. Biochem J. 1996 Oct 1;319 ( Pt 1):299-305. PMID: 8870682.

" Xi Not dangerous goods.

LKT N3378 S-Nitrosoglutathione 10 mg 158.8 NO donor. 57564-91-7 ≥98% 336.32 C10H16N4O7S C(CC(=O)NC(CSN=O)C(=O)NCC(=O)O)C(C(=O)O)N Ambient -20°C "Lohman AW, Weaver JL, Billaud M, et al. S-nitrosylation inhibits pannexin 1 channel function. J Biol Chem. 2012 Nov 16;287(47):39602-12. PMID: 23033481.

Servetnyk Z, Krjukova J, Gaston B, et al. Activation of chloride transport in CF airway epithelial cell lines and primary CF nasal epithelial cells by S-nitrosoglutathione. Respir Res. 2006 Oct 5;7:124. PMID: 17022806.

Carvalho-Filho MA, Ueno M, Hirabara SM, et al. S-nitrosation of the insulin receptor, insulin receptor substrate 1, and protein kinase B/Akt: a novel mechanism of insulin resistance. Diabetes. 2005 Apr;54(4):959-67. PMID: 15793233.

Jeon HK, Choi SU, Jung NP. Association of the ERK1/2 and p38 kinase pathways with nitric oxide-induced apoptosis and cell cycle arrest in colon cancer cells. Cell Biol Toxicol. 2005 Mar;21(2):115-25. PMID: 16142585.

Ciriolo MR, Aquilano K, De Martino A, et al. Differential role of superoxide and glutathione in S-nitrosoglutathione-mediated apoptosis: a rationale for mild forms of familial amyotrophic lateral sclerosis associated with less active Cu,Zn superoxide dismutase mutants. J Neurochem. 2001 Jun;77(6):1433-43. PMID: 11413228.

Dalle-Donne I, Milzani A, Giustarini D, et al. S-NO-actin: S-nitrosylation kinetics and the effect on isolated vascular smooth muscle. J Muscle Res Cell Motil. 2000 Feb;21(2):171-81. PMID: 10961840.

Messmer UK, Brüne B. Nitric oxide-induced apoptosis: p53-dependent and p53-independent signalling pathways. Biochem J. 1996 Oct 1;319 ( Pt 1):299-305. PMID: 8870682.

" Xi Not dangerous goods.

LKT N3378 S-Nitrosoglutathione 25 mg 212.5 NO donor. 57564-91-7 ≥98% 336.32 C10H16N4O7S C(CC(=O)NC(CSN=O)C(=O)NCC(=O)O)C(C(=O)O)N Ambient -20°C "Lohman AW, Weaver JL, Billaud M, et al. S-nitrosylation inhibits pannexin 1 channel function. J Biol Chem. 2012 Nov 16;287(47):39602-12. PMID: 23033481.

Servetnyk Z, Krjukova J, Gaston B, et al. Activation of chloride transport in CF airway epithelial cell lines and primary CF nasal epithelial cells by S-nitrosoglutathione. Respir Res. 2006 Oct 5;7:124. PMID: 17022806.

Carvalho-Filho MA, Ueno M, Hirabara SM, et al. S-nitrosation of the insulin receptor, insulin receptor substrate 1, and protein kinase B/Akt: a novel mechanism of insulin resistance. Diabetes. 2005 Apr;54(4):959-67. PMID: 15793233.

Jeon HK, Choi SU, Jung NP. Association of the ERK1/2 and p38 kinase pathways with nitric oxide-induced apoptosis and cell cycle arrest in colon cancer cells. Cell Biol Toxicol. 2005 Mar;21(2):115-25. PMID: 16142585.

Ciriolo MR, Aquilano K, De Martino A, et al. Differential role of superoxide and glutathione in S-nitrosoglutathione-mediated apoptosis: a rationale for mild forms of familial amyotrophic lateral sclerosis associated with less active Cu,Zn superoxide dismutase mutants. J Neurochem. 2001 Jun;77(6):1433-43. PMID: 11413228.

Dalle-Donne I, Milzani A, Giustarini D, et al. S-NO-actin: S-nitrosylation kinetics and the effect on isolated vascular smooth muscle. J Muscle Res Cell Motil. 2000 Feb;21(2):171-81. PMID: 10961840.

Messmer UK, Brüne B. Nitric oxide-induced apoptosis: p53-dependent and p53-independent signalling pathways. Biochem J. 1996 Oct 1;319 ( Pt 1):299-305. PMID: 8870682.

" Xi Not dangerous goods.

LKT R5878 Rotenone 1 g 75.3 Micronuclei formation inducer, antimitotic, oxidative phosphorylation inhibitor. (2R,6aS,12aS)-1,2,6,6a,12,12a-hexahydro-2-isopropenyl-8,9-dimethoxychromeno[3,4-b]furo[2,3-h]chromen-6-one 83-79-4 ≥97% 394.41 C23H22O6 CC(=C)C1CC2=C(O1)C=CC3=C2OC4COC5=CC(=C(C=C5C4C3=O)OC)OC Ambient Ambient "Johnson GE, Parry EM. Mechanistic investigations of low dose exposures to the genotoxic compounds bisphenol-A and rotenone. Mutat Res. 2008 Mar 12;651(1-2):56-63. PMID: 18083626.

Sherer TB, Richardson JR, Testa CM, et al. Mechanism of toxicity of pesticides acting at complex I: relevance to environmental etiologies of Parkinson's disease. J Neurochem. 2007 Mar;100(6):1469-79. PMID: 17241123.

Wyatt CN, Buckler KJ. The effect of mitochondrial inhibitors on membrane currents in isolated neonatal rat carotid body type I cells. J Physiol. 2004 Apr 1;556(Pt 1):175-91. PMID: 14724184.

Gao HM, Hong JS, Zhang W, et al. Distinct role for microglia in rotenone-induced degeneration of dopaminergic neurons. J Neurosci. 2002 Feb 1;22(3):782-90. PMID: 11826108.

" T, N "UN number: 2811     Class:  6.1     Packing group:  III 

Proper shipping name:  Toxic solids, organic, n.o.s. (Rotenone)     

Reportable quantity (RQ)     Marine pollutant:  yes     Poison inhalation hazard:  No"

LKT R5878 Rotenone 5 g 242.7 Micronuclei formation inducer, antimitotic, oxidative phosphorylation inhibitor. (2R,6aS,12aS)-1,2,6,6a,12,12a-hexahydro-2-isopropenyl-8,9-dimethoxychromeno[3,4-b]furo[2,3-h]chromen-6-one 83-79-4 ≥97% 394.41 C23H22O6 CC(=C)C1CC2=C(O1)C=CC3=C2OC4COC5=CC(=C(C=C5C4C3=O)OC)OC Ambient Ambient "Johnson GE, Parry EM. Mechanistic investigations of low dose exposures to the genotoxic compounds bisphenol-A and rotenone. Mutat Res. 2008 Mar 12;651(1-2):56-63. PMID: 18083626.

Sherer TB, Richardson JR, Testa CM, et al. Mechanism of toxicity of pesticides acting at complex I: relevance to environmental etiologies of Parkinson's disease. J Neurochem. 2007 Mar;100(6):1469-79. PMID: 17241123.

Wyatt CN, Buckler KJ. The effect of mitochondrial inhibitors on membrane currents in isolated neonatal rat carotid body type I cells. J Physiol. 2004 Apr 1;556(Pt 1):175-91. PMID: 14724184.

Gao HM, Hong JS, Zhang W, et al. Distinct role for microglia in rotenone-induced degeneration of dopaminergic neurons. J Neurosci. 2002 Feb 1;22(3):782-90. PMID: 11826108.

" T, N "UN number: 2811     Class:  6.1     Packing group:  III 

Proper shipping name:  Toxic solids, organic, n.o.s. (Rotenone)     

Reportable quantity (RQ)     Marine pollutant:  yes     Poison inhalation hazard:  No"

LKT R5878 Rotenone 25 g 535.7 Micronuclei formation inducer, antimitotic, oxidative phosphorylation inhibitor. (2R,6aS,12aS)-1,2,6,6a,12,12a-hexahydro-2-isopropenyl-8,9-dimethoxychromeno[3,4-b]furo[2,3-h]chromen-6-one 83-79-4 ≥97% 394.41 C23H22O6 CC(=C)C1CC2=C(O1)C=CC3=C2OC4COC5=CC(=C(C=C5C4C3=O)OC)OC Ambient Ambient "Johnson GE, Parry EM. Mechanistic investigations of low dose exposures to the genotoxic compounds bisphenol-A and rotenone. Mutat Res. 2008 Mar 12;651(1-2):56-63. PMID: 18083626.

Sherer TB, Richardson JR, Testa CM, et al. Mechanism of toxicity of pesticides acting at complex I: relevance to environmental etiologies of Parkinson's disease. J Neurochem. 2007 Mar;100(6):1469-79. PMID: 17241123.

Wyatt CN, Buckler KJ. The effect of mitochondrial inhibitors on membrane currents in isolated neonatal rat carotid body type I cells. J Physiol. 2004 Apr 1;556(Pt 1):175-91. PMID: 14724184.

Gao HM, Hong JS, Zhang W, et al. Distinct role for microglia in rotenone-induced degeneration of dopaminergic neurons. J Neurosci. 2002 Feb 1;22(3):782-90. PMID: 11826108.

" T, N "UN number: 2811     Class:  6.1     Packing group:  III 

Proper shipping name:  Toxic solids, organic, n.o.s. (Rotenone)     

Reportable quantity (RQ)     Marine pollutant:  yes     Poison inhalation hazard:  No"

LKT V3345 Vildagliptin 10 mg 58.7 DPP4 inhibitor. "(2S)-(((3-Hydroxyadamantan-1-yl)amino)acetyl)pyrrolidine-2-carbonitrile; Galvus; (2R)-1-(2-((3-Hydroxy-1-

adamantyl)amino)acetyl)pyrrolidine-2-carbonitrile; 1-(2-((3-Hydroxy-1-adamantyl)amino)

acetyl)pyrrolidine -2-carbonitrile" 274901-16-5 ≥97% 303.4 C17H25N3O2 C1CC(N(C1)C(=O)CNC23CC4CC(C2)CC(C4)(C3)O)C#N Ambient -20°C "Kosaraju J, Murthy V, Khatwal RB, et al. Vildagliptin: an anti-diabetes agent ameliorates cognitive deficits and pathology observed in streptozotocin-induced Alzheimer's disease. J Pharm Pharmacol. 2013 Dec;65(12):1773-84. PMID: 24117480.

Shimizu S, Hosooka T, Matsuda T, et al. DPP4 inhibitor vildagliptin preserves β-cell mass through amelioration of endoplasmic reticulum stress in C/EBPB transgenic mice. J Mol Endocrinol. 2012 Aug 30;49(2):125-35. PMID: 22822047.

Thornberry NA, Gallwitz B. Mechanism of action of inhibitors of dipeptidyl-peptidase-4 (DPP-4). Best Pract Res Clin Endocrinol Metab. 2009 Aug;23(4):479-86. PMID: 19748065.

Balas B, Baig MR, Watson C, et al. The dipeptidyl peptidase IV inhibitor vildagliptin suppresses endogenous glucose production and enhances islet function after single-dose administration in type 2 diabetic patients. J Clin Endocrinol Metab. 2007 Apr;92(4):1249-55. PMID: 17244786.

" Not dangerous goods.

LKT V3345 Vildagliptin 25 mg 117.1 DPP4 inhibitor. "(2S)-(((3-Hydroxyadamantan-1-yl)amino)acetyl)pyrrolidine-2-carbonitrile; Galvus; (2R)-1-(2-((3-Hydroxy-1-

adamantyl)amino)acetyl)pyrrolidine-2-carbonitrile; 1-(2-((3-Hydroxy-1-adamantyl)amino)

acetyl)pyrrolidine -2-carbonitrile" 274901-16-5 ≥97% 303.4 C17H25N3O2 C1CC(N(C1)C(=O)CNC23CC4CC(C2)CC(C4)(C3)O)C#N Ambient -20°C "Kosaraju J, Murthy V, Khatwal RB, et al. Vildagliptin: an anti-diabetes agent ameliorates cognitive deficits and pathology observed in streptozotocin-induced Alzheimer's disease. J Pharm Pharmacol. 2013 Dec;65(12):1773-84. PMID: 24117480.

Shimizu S, Hosooka T, Matsuda T, et al. DPP4 inhibitor vildagliptin preserves β-cell mass through amelioration of endoplasmic reticulum stress in C/EBPB transgenic mice. J Mol Endocrinol. 2012 Aug 30;49(2):125-35. PMID: 22822047.

Thornberry NA, Gallwitz B. Mechanism of action of inhibitors of dipeptidyl-peptidase-4 (DPP-4). Best Pract Res Clin Endocrinol Metab. 2009 Aug;23(4):479-86. PMID: 19748065.

Balas B, Baig MR, Watson C, et al. The dipeptidyl peptidase IV inhibitor vildagliptin suppresses endogenous glucose production and enhances islet function after single-dose administration in type 2 diabetic patients. J Clin Endocrinol Metab. 2007 Apr;92(4):1249-55. PMID: 17244786.

" Not dangerous goods.

LKT V3345 Vildagliptin 100 mg 293.1 DPP4 inhibitor. "(2S)-(((3-Hydroxyadamantan-1-yl)amino)acetyl)pyrrolidine-2-carbonitrile; Galvus; (2R)-1-(2-((3-Hydroxy-1-

adamantyl)amino)acetyl)pyrrolidine-2-carbonitrile; 1-(2-((3-Hydroxy-1-adamantyl)amino)

acetyl)pyrrolidine -2-carbonitrile" 274901-16-5 ≥97% 303.4 C17H25N3O2 C1CC(N(C1)C(=O)CNC23CC4CC(C2)CC(C4)(C3)O)C#N Ambient -20°C "Kosaraju J, Murthy V, Khatwal RB, et al. Vildagliptin: an anti-diabetes agent ameliorates cognitive deficits and pathology observed in streptozotocin-induced Alzheimer's disease. J Pharm Pharmacol. 2013 Dec;65(12):1773-84. PMID: 24117480.

Shimizu S, Hosooka T, Matsuda T, et al. DPP4 inhibitor vildagliptin preserves β-cell mass through amelioration of endoplasmic reticulum stress in C/EBPB transgenic mice. J Mol Endocrinol. 2012 Aug 30;49(2):125-35. PMID: 22822047.

Thornberry NA, Gallwitz B. Mechanism of action of inhibitors of dipeptidyl-peptidase-4 (DPP-4). Best Pract Res Clin Endocrinol Metab. 2009 Aug;23(4):479-86. PMID: 19748065.

Balas B, Baig MR, Watson C, et al. The dipeptidyl peptidase IV inhibitor vildagliptin suppresses endogenous glucose production and enhances islet function after single-dose administration in type 2 diabetic patients. J Clin Endocrinol Metab. 2007 Apr;92(4):1249-55. PMID: 17244786.

" Not dangerous goods.

LKT T1854 Tenofovir Monohydrate 100 mg 97.2 Nucleotide analog; RT inhibitor. 206184-49-8 ≥98% 305.23 C9H14N5O4P H2O CC(CN1C=NC2=C1N=CN=C2N)OCP(=O)(O)O.O Ambient Ambient "Qiu LP, Chen L, Chen KP. Antihepatitis B therapy: a review of current medications and novel small molecule inhibitors. Fundam Clin Pharmacol. 2013 Oct 4. [Epub ahead of print]. PMID: 24118072.

Iyidogan P, Anderson KS. Recent findings on the mechanisms involved in tenofovir resistance. Antivir Chem Chemother. 2013 Jun 6. [Epub ahead of print]. PMID: 23744599.

Greggs WM 3rd, Clouser CL, Patterson SE, et al. Discovery of drugs that possess activity against feline leukemia virus. J Gen Virol. 2012 Apr;93(Pt 4):900-5. PMID: 22258856.

Rohan LC, Moncla BJ, Kunjara Na Ayudhya RP, et al. In vitro and ex vivo testing of tenofovir shows it is effective as an HIV-1 microbicide. PLoS One. 2010 Feb 19;5(2):e9310. PMID: 20174579.

" Not dangerous goods.

LKT T1854 Tenofovir Monohydrate 250 mg 167.4 Nucleotide analog; RT inhibitor. 206184-49-8 ≥98% 305.23 C9H14N5O4P H2O CC(CN1C=NC2=C1N=CN=C2N)OCP(=O)(O)O.O Ambient Ambient "Qiu LP, Chen L, Chen KP. Antihepatitis B therapy: a review of current medications and novel small molecule inhibitors. Fundam Clin Pharmacol. 2013 Oct 4. [Epub ahead of print]. PMID: 24118072.

Iyidogan P, Anderson KS. Recent findings on the mechanisms involved in tenofovir resistance. Antivir Chem Chemother. 2013 Jun 6. [Epub ahead of print]. PMID: 23744599.

Greggs WM 3rd, Clouser CL, Patterson SE, et al. Discovery of drugs that possess activity against feline leukemia virus. J Gen Virol. 2012 Apr;93(Pt 4):900-5. PMID: 22258856.

Rohan LC, Moncla BJ, Kunjara Na Ayudhya RP, et al. In vitro and ex vivo testing of tenofovir shows it is effective as an HIV-1 microbicide. PLoS One. 2010 Feb 19;5(2):e9310. PMID: 20174579.

" Not dangerous goods.

LKT T1854 Tenofovir Monohydrate 1 g 301.5 Nucleotide analog; RT inhibitor. 206184-49-8 ≥98% 305.23 C9H14N5O4P H2O CC(CN1C=NC2=C1N=CN=C2N)OCP(=O)(O)O.O Ambient Ambient "Qiu LP, Chen L, Chen KP. Antihepatitis B therapy: a review of current medications and novel small molecule inhibitors. Fundam Clin Pharmacol. 2013 Oct 4. [Epub ahead of print]. PMID: 24118072.

Iyidogan P, Anderson KS. Recent findings on the mechanisms involved in tenofovir resistance. Antivir Chem Chemother. 2013 Jun 6. [Epub ahead of print]. PMID: 23744599.

Greggs WM 3rd, Clouser CL, Patterson SE, et al. Discovery of drugs that possess activity against feline leukemia virus. J Gen Virol. 2012 Apr;93(Pt 4):900-5. PMID: 22258856.

Rohan LC, Moncla BJ, Kunjara Na Ayudhya RP, et al. In vitro and ex vivo testing of tenofovir shows it is effective as an HIV-1 microbicide. PLoS One. 2010 Feb 19;5(2):e9310. PMID: 20174579.

" Not dangerous goods.

LKT L3453 Linezolid 1 g 113.9 Oxazolidinone; protein synthesis inhibitor. N-[[(5S)-3-[3-Fluoro-4-(4-morpholinyl)phenyl]-2-oxo-5-oxazolidinyl]methyl]acetamide 165800-03-3 ≥98% 337.35 C16H20FN3O4 CC(=O)NCC1CN(C(=O)O1)C2=CC(=C(C=C2)N3CCOCC3)F Ambient Ambient Moderately soluble in water (3 mg/mL).  Soluble in DMSO (>20 mg/mL). "Long KS, Vester B. Resistance to linezolid caused by modifications at its binding site on the ribosome. Antimicrob Agents Chemother. 2012 Feb;56(2):603-12. PMID: 22143525.

Kombian SB, Phillips OA. In vitro electrophysiological investigations of the acute effects of linezolid and novel oxazolidinones on central nervous system neurons. Neuroscience. 2011 Apr 28;180:53-63. PMID: 21296129.

Ippolito JA, Kanyo ZF, Wang D, et al. Crystal structure of the oxazolidinone antibiotic linezolid bound to the 50S ribosomal subunit. J Med Chem. 2008 Jun 26;51(12):3353-6. PMID: 18494460.

Brickner SJ, Hutchinson DK, Barbachyn MR, et.al.  Synthesis and antibacterial activity of U-100592 and U-100766, two oxazolidinone antibacterial agents for the potential treatment of multidrug-resistant gram-positive bacterial infections.  J Med Chem. 1996 Feb 2;39(3):673-9.  PMID: 8576909 DOI: 10.1021/jm9509556

" Xn Not dangerous goods.

LKT L3453 Linezolid 5 g 293.1 Oxazolidinone; protein synthesis inhibitor. N-[[(5S)-3-[3-Fluoro-4-(4-morpholinyl)phenyl]-2-oxo-5-oxazolidinyl]methyl]acetamide 165800-03-3 ≥98% 337.35 C16H20FN3O4 CC(=O)NCC1CN(C(=O)O1)C2=CC(=C(C=C2)N3CCOCC3)F Ambient Ambient Moderately soluble in water (3 mg/mL).  Soluble in DMSO (>20 mg/mL). "Long KS, Vester B. Resistance to linezolid caused by modifications at its binding site on the ribosome. Antimicrob Agents Chemother. 2012 Feb;56(2):603-12. PMID: 22143525.

Kombian SB, Phillips OA. In vitro electrophysiological investigations of the acute effects of linezolid and novel oxazolidinones on central nervous system neurons. Neuroscience. 2011 Apr 28;180:53-63. PMID: 21296129.

Ippolito JA, Kanyo ZF, Wang D, et al. Crystal structure of the oxazolidinone antibiotic linezolid bound to the 50S ribosomal subunit. J Med Chem. 2008 Jun 26;51(12):3353-6. PMID: 18494460.

Brickner SJ, Hutchinson DK, Barbachyn MR, et.al.  Synthesis and antibacterial activity of U-100592 and U-100766, two oxazolidinone antibacterial agents for the potential treatment of multidrug-resistant gram-positive bacterial infections.  J Med Chem. 1996 Feb 2;39(3):673-9.  PMID: 8576909 DOI: 10.1021/jm9509556

" Xn Not dangerous goods.

LKT L3453 Linezolid 25 g 669.7 Oxazolidinone; protein synthesis inhibitor. N-[[(5S)-3-[3-Fluoro-4-(4-morpholinyl)phenyl]-2-oxo-5-oxazolidinyl]methyl]acetamide 165800-03-3 ≥98% 337.35 C16H20FN3O4 CC(=O)NCC1CN(C(=O)O1)C2=CC(=C(C=C2)N3CCOCC3)F Ambient Ambient Moderately soluble in water (3 mg/mL).  Soluble in DMSO (>20 mg/mL). "Long KS, Vester B. Resistance to linezolid caused by modifications at its binding site on the ribosome. Antimicrob Agents Chemother. 2012 Feb;56(2):603-12. PMID: 22143525.

Kombian SB, Phillips OA. In vitro electrophysiological investigations of the acute effects of linezolid and novel oxazolidinones on central nervous system neurons. Neuroscience. 2011 Apr 28;180:53-63. PMID: 21296129.

Ippolito JA, Kanyo ZF, Wang D, et al. Crystal structure of the oxazolidinone antibiotic linezolid bound to the 50S ribosomal subunit. J Med Chem. 2008 Jun 26;51(12):3353-6. PMID: 18494460.

Brickner SJ, Hutchinson DK, Barbachyn MR, et.al.  Synthesis and antibacterial activity of U-100592 and U-100766, two oxazolidinone antibacterial agents for the potential treatment of multidrug-resistant gram-positive bacterial infections.  J Med Chem. 1996 Feb 2;39(3):673-9.  PMID: 8576909 DOI: 10.1021/jm9509556

" Xn Not dangerous goods.

LKT G0104 Gabexate Mesylate 10 mg 108.9 Proteasome inhibitor. 4-[[6-[ (aminoiminomethyl) amino]-1-oxohexyl]oxyl]benzoic acid ethyl ester mesylate salt 56974-61-9 ≥98% 417.48 C16H24N3O4 CH3O3S CCOC(=O)C1=CC=C(C=C1)OC(=O)CCCCCN=C(N)N.CS(=O)(=O)O Ambient Ambient "Brandi G, Tavolari S, Guarnieri T, et al. Antiprotease strategy in pancreatic cancer treatment: emergence from a preclinical study. Pancreas. 2014 Jan;43(1):53-63. PMID: 24201777.

Hsieh HP, Hsu JT. Strategies of development of antiviral agents directed against influenza virus replication. Curr Pharm Des. 2007;13(34):3531-42. PMID: 18220789.

Uchima Y, Sawada T, Nishihara T, et al. Inhibition and mechanism of action of a protease inhibitor in human pancreatic cancer cells. Pancreas. 2004 Aug;29(2):123-31. PMID: 15257104.

Yuksel M, Okajima K, Uchiba M, et al. Gabexate mesilate, a synthetic protease inhibitor, inhibits lipopolysaccharide-induced tumor necrosis factor-alpha production by inhibiting activation of both nuclear factor-kappaB and activator protein-1 in human monocytes. J Pharmacol Exp Ther. 2003 Apr;305(1):298-305. PMID: 12649382.

Aosasa S, Ono S, Mochizuki H, et al. Mechanism of the inhibitory effect of protease inhibitor on tumor necrosis factor alpha production of monocytes. Shock. 2001 Feb;15(2):101-5. PMID: 11220636.

" Xn Not dangerous goods.

LKT G0104 Gabexate Mesylate 100 mg 544.1 Proteasome inhibitor. 4-[[6-[ (aminoiminomethyl) amino]-1-oxohexyl]oxyl]benzoic acid ethyl ester mesylate salt 56974-61-9 ≥98% 417.48 C16H24N3O4 CH3O3S CCOC(=O)C1=CC=C(C=C1)OC(=O)CCCCCN=C(N)N.CS(=O)(=O)O Ambient Ambient "Brandi G, Tavolari S, Guarnieri T, et al. Antiprotease strategy in pancreatic cancer treatment: emergence from a preclinical study. Pancreas. 2014 Jan;43(1):53-63. PMID: 24201777.

Hsieh HP, Hsu JT. Strategies of development of antiviral agents directed against influenza virus replication. Curr Pharm Des. 2007;13(34):3531-42. PMID: 18220789.

Uchima Y, Sawada T, Nishihara T, et al. Inhibition and mechanism of action of a protease inhibitor in human pancreatic cancer cells. Pancreas. 2004 Aug;29(2):123-31. PMID: 15257104.

Yuksel M, Okajima K, Uchiba M, et al. Gabexate mesilate, a synthetic protease inhibitor, inhibits lipopolysaccharide-induced tumor necrosis factor-alpha production by inhibiting activation of both nuclear factor-kappaB and activator protein-1 in human monocytes. J Pharmacol Exp Ther. 2003 Apr;305(1):298-305. PMID: 12649382.

Aosasa S, Ono S, Mochizuki H, et al. Mechanism of the inhibitory effect of protease inhibitor on tumor necrosis factor alpha production of monocytes. Shock. 2001 Feb;15(2):101-5. PMID: 11220636.

" Xn Not dangerous goods.

LKT G0104 Gabexate Mesylate 250 mg 1088.3 Proteasome inhibitor. 4-[[6-[ (aminoiminomethyl) amino]-1-oxohexyl]oxyl]benzoic acid ethyl ester mesylate salt 56974-61-9 ≥98% 417.48 C16H24N3O4 CH3O3S CCOC(=O)C1=CC=C(C=C1)OC(=O)CCCCCN=C(N)N.CS(=O)(=O)O Ambient Ambient "Brandi G, Tavolari S, Guarnieri T, et al. Antiprotease strategy in pancreatic cancer treatment: emergence from a preclinical study. Pancreas. 2014 Jan;43(1):53-63. PMID: 24201777.

Hsieh HP, Hsu JT. Strategies of development of antiviral agents directed against influenza virus replication. Curr Pharm Des. 2007;13(34):3531-42. PMID: 18220789.

Uchima Y, Sawada T, Nishihara T, et al. Inhibition and mechanism of action of a protease inhibitor in human pancreatic cancer cells. Pancreas. 2004 Aug;29(2):123-31. PMID: 15257104.

Yuksel M, Okajima K, Uchiba M, et al. Gabexate mesilate, a synthetic protease inhibitor, inhibits lipopolysaccharide-induced tumor necrosis factor-alpha production by inhibiting activation of both nuclear factor-kappaB and activator protein-1 in human monocytes. J Pharmacol Exp Ther. 2003 Apr;305(1):298-305. PMID: 12649382.

Aosasa S, Ono S, Mochizuki H, et al. Mechanism of the inhibitory effect of protease inhibitor on tumor necrosis factor alpha production of monocytes. Shock. 2001 Feb;15(2):101-5. PMID: 11220636.

" Xn Not dangerous goods.

LKT C3472 Cisatracurium Besylate 25 mg 100.5 Non-depolarizing NMJ blocker; nAChR and M2 mAChR antagonist. 96946-42-8 ≥95% 1243.48 C53H72N2O12 2C6H5O3S C[N+]1(CCC2=CC(=C(C=C2C1CC3=CC(=C(C=C3)OC)OC)OC)OC)CCC(=O)OCCCCCOC(=O)CC[N+]4(CCC5=CC(=C(C=C5C4CC6=CC(=C(C=C6)OC)OC)OC)OC)C.C1=CC=C(C=C1)S(=O)(=O)[O-].C1=CC=C(C=C1)S(=O)(=O)[O-] Ambient Ambient "Liu M, Dilger JP. Synergy between pairs of competitive antagonists at adult human muscle acetylcholine receptors. Anesth Analg. 2008 Aug;107(2):525-33. PMID: 18633030.

Patterson E, Scherlag BJ, Zhou J, et al. Antifibrillatory actions of cisatracurium: an atrial specific M2 receptor antagonist. J Cardiovasc Electrophysiol. 2008 Aug;19(8):861-8. PMID: 18363689.

Dilger JP, Vidal AM, Liu M, et al. Roles of amino acids and subunits in determining the inhibition of nicotinic acetylcholine receptors by competitive antagonists. Anesthesiology. 2007 Jun;106(6):1186-95. PMID: 17525594.

Jonsson M, Gurley D, Dabrowski M, et al. Distinct pharmacologic properties of neuromuscular blocking agents on human neuronal nicotinic acetylcholine receptors: a possible explanation for the train-of-four fade. Anesthesiology. 2006 Sep;105(3):521-33. PMID: 16931985.

" "UN number: 2811     Class: 6.1     Packing Group: II

Proper shipping name: Toxic solid, organic, n.o.s. (Cisatracurium besylate)"

LKT C3472 Cisatracurium Besylate 100 mg 335 Non-depolarizing NMJ blocker; nAChR and M2 mAChR antagonist. 96946-42-8 ≥95% 1243.48 C53H72N2O12 2C6H5O3S C[N+]1(CCC2=CC(=C(C=C2C1CC3=CC(=C(C=C3)OC)OC)OC)OC)CCC(=O)OCCCCCOC(=O)CC[N+]4(CCC5=CC(=C(C=C5C4CC6=CC(=C(C=C6)OC)OC)OC)OC)C.C1=CC=C(C=C1)S(=O)(=O)[O-].C1=CC=C(C=C1)S(=O)(=O)[O-] Ambient Ambient "Liu M, Dilger JP. Synergy between pairs of competitive antagonists at adult human muscle acetylcholine receptors. Anesth Analg. 2008 Aug;107(2):525-33. PMID: 18633030.

Patterson E, Scherlag BJ, Zhou J, et al. Antifibrillatory actions of cisatracurium: an atrial specific M2 receptor antagonist. J Cardiovasc Electrophysiol. 2008 Aug;19(8):861-8. PMID: 18363689.

Dilger JP, Vidal AM, Liu M, et al. Roles of amino acids and subunits in determining the inhibition of nicotinic acetylcholine receptors by competitive antagonists. Anesthesiology. 2007 Jun;106(6):1186-95. PMID: 17525594.

Jonsson M, Gurley D, Dabrowski M, et al. Distinct pharmacologic properties of neuromuscular blocking agents on human neuronal nicotinic acetylcholine receptors: a possible explanation for the train-of-four fade. Anesthesiology. 2006 Sep;105(3):521-33. PMID: 16931985.

" "UN number: 2811     Class: 6.1     Packing Group: II

Proper shipping name: Toxic solid, organic, n.o.s. (Cisatracurium besylate)"

LKT C3472 Cisatracurium Besylate 500 mg 1306 Non-depolarizing NMJ blocker; nAChR and M2 mAChR antagonist. 96946-42-8 ≥95% 1243.48 C53H72N2O12 2C6H5O3S C[N+]1(CCC2=CC(=C(C=C2C1CC3=CC(=C(C=C3)OC)OC)OC)OC)CCC(=O)OCCCCCOC(=O)CC[N+]4(CCC5=CC(=C(C=C5C4CC6=CC(=C(C=C6)OC)OC)OC)OC)C.C1=CC=C(C=C1)S(=O)(=O)[O-].C1=CC=C(C=C1)S(=O)(=O)[O-] Ambient Ambient "Liu M, Dilger JP. Synergy between pairs of competitive antagonists at adult human muscle acetylcholine receptors. Anesth Analg. 2008 Aug;107(2):525-33. PMID: 18633030.

Patterson E, Scherlag BJ, Zhou J, et al. Antifibrillatory actions of cisatracurium: an atrial specific M2 receptor antagonist. J Cardiovasc Electrophysiol. 2008 Aug;19(8):861-8. PMID: 18363689.

Dilger JP, Vidal AM, Liu M, et al. Roles of amino acids and subunits in determining the inhibition of nicotinic acetylcholine receptors by competitive antagonists. Anesthesiology. 2007 Jun;106(6):1186-95. PMID: 17525594.

Jonsson M, Gurley D, Dabrowski M, et al. Distinct pharmacologic properties of neuromuscular blocking agents on human neuronal nicotinic acetylcholine receptors: a possible explanation for the train-of-four fade. Anesthesiology. 2006 Sep;105(3):521-33. PMID: 16931985.

" "UN number: 2811     Class: 6.1     Packing Group: II

Proper shipping name: Toxic solid, organic, n.o.s. (Cisatracurium besylate)"

LKT A4944 Amlexanox 500 mg 58.7 Azoxanthone derivative; S100A12 and S100A13 inhibitor, TBK1 inhibitor, 68302-57-8 ≥98% 298.29 C16H14N2O4 CC(C)C1=CC2=C(C=C1)OC3=NC(=C(C=C3C2=O)C(=O)O)N Ambient Ambient Ethanol (0.58 mg/ml), DMSO (10 mg/ml), DMF (14 mg/ml), and 1:1 DMSO: PBS (pH 7.2) (0.5 mg/ml) "Reilly SM, Chiang SH, Decker SJ, et al. An inhibitor of the protein kinases TBK1 and IKK-ɛ improves obesity-related metabolic dysfunctions in mice. Nat Med. 2013 Mar;19(3):313-21. PMID: 23396211.

Bell J. Amlexanox for the treatment of recurrent aphthous ulcers. Clin Drug Investig. 2005;25(9):555-66. PMID: 17532700.

Landriscina M, Prudovsky I, Mouta Carreira C, et al. Amlexanox reversibly inhibits cell migration and proliferation and induces the Src-dependent disassembly of actin stress fibers in vitro. J Biol Chem. 2000 Oct 20;275(42):32753-62. PMID: 10921913.

Shishibori T, Oyama Y, Matsushita O, Yet al. Three distinct anti-allergic drugs, amlexanox, cromolyn and tranilast, bind to S100A12 and S100A13 of the S100 protein family. Biochem J. 1999 Mar 15;338 ( Pt 3):583-9. PMID: 10051426.

Makino H, Saijo T, Ashida Y, et al. Mechanism of action of an antiallergic agent, amlexanox (AA-673), in inhibiting histamine release from mast cells. Acceleration of cAMP generation and inhibition of phosphodiesterase. Int Arch Allergy Appl Immunol. 1987;82(1):66-71. PMID: 2433225.

Saijo T, Makino H, Tamura S, et al. The antiallergic agent amoxanox suppresses SRS-A generation by inhibiting lipoxygenase. Int Arch Allergy Appl Immunol. 1986;79(3):231-7. PMID: 2868995.

" Not dangerous goods.

LKT A4944 Amlexanox 1 g 83.7 Azoxanthone derivative; S100A12 and S100A13 inhibitor, TBK1 inhibitor, 68302-57-8 ≥98% 298.29 C16H14N2O4 CC(C)C1=CC2=C(C=C1)OC3=NC(=C(C=C3C2=O)C(=O)O)N Ambient Ambient Ethanol (0.58 mg/ml), DMSO (10 mg/ml), DMF (14 mg/ml), and 1:1 DMSO: PBS (pH 7.2) (0.5 mg/ml) "Reilly SM, Chiang SH, Decker SJ, et al. An inhibitor of the protein kinases TBK1 and IKK-ɛ improves obesity-related metabolic dysfunctions in mice. Nat Med. 2013 Mar;19(3):313-21. PMID: 23396211.

Bell J. Amlexanox for the treatment of recurrent aphthous ulcers. Clin Drug Investig. 2005;25(9):555-66. PMID: 17532700.

Landriscina M, Prudovsky I, Mouta Carreira C, et al. Amlexanox reversibly inhibits cell migration and proliferation and induces the Src-dependent disassembly of actin stress fibers in vitro. J Biol Chem. 2000 Oct 20;275(42):32753-62. PMID: 10921913.

Shishibori T, Oyama Y, Matsushita O, Yet al. Three distinct anti-allergic drugs, amlexanox, cromolyn and tranilast, bind to S100A12 and S100A13 of the S100 protein family. Biochem J. 1999 Mar 15;338 ( Pt 3):583-9. PMID: 10051426.

Makino H, Saijo T, Ashida Y, et al. Mechanism of action of an antiallergic agent, amlexanox (AA-673), in inhibiting histamine release from mast cells. Acceleration of cAMP generation and inhibition of phosphodiesterase. Int Arch Allergy Appl Immunol. 1987;82(1):66-71. PMID: 2433225.

Saijo T, Makino H, Tamura S, et al. The antiallergic agent amoxanox suppresses SRS-A generation by inhibiting lipoxygenase. Int Arch Allergy Appl Immunol. 1986;79(3):231-7. PMID: 2868995.

" Not dangerous goods.

LKT A4944 Amlexanox 5 g 335 Azoxanthone derivative; S100A12 and S100A13 inhibitor, TBK1 inhibitor, 68302-57-8 ≥98% 298.29 C16H14N2O4 CC(C)C1=CC2=C(C=C1)OC3=NC(=C(C=C3C2=O)C(=O)O)N Ambient Ambient Ethanol (0.58 mg/ml), DMSO (10 mg/ml), DMF (14 mg/ml), and 1:1 DMSO: PBS (pH 7.2) (0.5 mg/ml) "Reilly SM, Chiang SH, Decker SJ, et al. An inhibitor of the protein kinases TBK1 and IKK-ɛ improves obesity-related metabolic dysfunctions in mice. Nat Med. 2013 Mar;19(3):313-21. PMID: 23396211.

Bell J. Amlexanox for the treatment of recurrent aphthous ulcers. Clin Drug Investig. 2005;25(9):555-66. PMID: 17532700.

Landriscina M, Prudovsky I, Mouta Carreira C, et al. Amlexanox reversibly inhibits cell migration and proliferation and induces the Src-dependent disassembly of actin stress fibers in vitro. J Biol Chem. 2000 Oct 20;275(42):32753-62. PMID: 10921913.

Shishibori T, Oyama Y, Matsushita O, Yet al. Three distinct anti-allergic drugs, amlexanox, cromolyn and tranilast, bind to S100A12 and S100A13 of the S100 protein family. Biochem J. 1999 Mar 15;338 ( Pt 3):583-9. PMID: 10051426.

Makino H, Saijo T, Ashida Y, et al. Mechanism of action of an antiallergic agent, amlexanox (AA-673), in inhibiting histamine release from mast cells. Acceleration of cAMP generation and inhibition of phosphodiesterase. Int Arch Allergy Appl Immunol. 1987;82(1):66-71. PMID: 2433225.

Saijo T, Makino H, Tamura S, et al. The antiallergic agent amoxanox suppresses SRS-A generation by inhibiting lipoxygenase. Int Arch Allergy Appl Immunol. 1986;79(3):231-7. PMID: 2868995.

" Not dangerous goods.

LKT M3312 Microginin 690 Methyl Ester 100 µg 606.7 Found in Microcystis; protein phosphatase, ACE, leucine aminopeptidase inhibitor. ≥95% 704.87 C35H52N4O9S Blue Ice -20°C Soluble in methanol or DMSO "Schatz D, Keren Y, Vardi A, et al. Towards clarification of the biological role of microcystins, a family of cyanobacterial toxins. Environ Microbiol. 2007 Apr;9(4):965-70. PMID: 17359268.

Kraft M, Schleberger C, Weckesser J, et al. Binding structure of the leucine aminopeptidase inhibitor microginin FR1. FEBS Lett. 2006 Dec 22;580(30):6943-7. PMID: 17157838.

Runnage ME, Burke AJ, Davies SG, et al. Asymmetric Synthesis of the N-terminal component of Microginin: (2S,3R)-3-Amino-2-Hydroxydecanoic Acid, its (2R,3R)-Epimer and (3R)-3-Aminodecanoic Acid. Tetrahedron: Asymmetry. 1995;6(1):165-176. 

"

LKT M3308 Microginin 527 Methyl Ester 50 µg 728.1 Found in Microcystis; protein phosphatase, ACE, leucine aminopeptidase inhibitor. ≥95% 541.7 C26H43N3O7S Blue Ice -20°C "Schatz D, Keren Y, Vardi A, et al. Towards clarification of the biological role of microcystins, a family of cyanobacterial toxins. Environ Microbiol. 2007 Apr;9(4):965-70. PMID: 17359268.

Kraft M, Schleberger C, Weckesser J, et al. Binding structure of the leucine aminopeptidase inhibitor microginin FR1. FEBS Lett. 2006 Dec 22;580(30):6943-7. PMID: 17157838.

Runnage ME, Burke AJ, Davies SG, et al. Asymmetric Synthesis of the N-terminal component of Microginin: (2S,3R)-3-Amino-2-Hydroxydecanoic Acid, its (2R,3R)-Epimer and (3R)-3-Aminodecanoic Acid. Tetrahedron: Asymmetry. 1995;6(1):165-176. 

"

LKT C9602 Cyanopeptolin 1041 100 µg 606.7 Toxin produced by Microcystis; serine protease inhibitor. CYP1041 ≥95% 1041.7 C49H69ClN10O13 Blue Ice -20°C "Silva-Stenico ME, Rigonato J, Leal MG, et al. Non-ribosomal halogenated protease inhibitors from cyanobacterial isolates as attractive drug targets. Curr Med Chem. 2012;19(30):5205-13. PMID: 22934766.

Gademann K, Portmann C, Blom JF, et al. Multiple toxin production in the cyanobacterium microcystis: isolation of the toxic protease inhibitor cyanopeptolin 1020. J Nat Prod. 2010 May 28;73(5):980-4. PMID: 20405925.

Choi H, Oh SK, Yih W, et al. Cyanopeptoline CB071: a cyclic depsipeptide isolated from the freshwater cyanobacterium Aphanocapsa sp. Chem Pharm Bull (Tokyo). 2008 Aug;56(8):1191-3. PMID: 18670126.

von Elert E, Oberer L, Merkel P, et al. Cyanopeptolin 954, a chlorine-containing chymotrypsin inhibitor of Microcystis aeruginosa NIVA Cya 43. J Nat Prod. 2005 Sep;68(9):1324-7. PMID: 16180807.

Neumann U, Campos V, Cantarero S, et al. Co-occurrence of non-toxic (cyanopeptolin) and toxic (microcystin) peptides in a bloom of Microcystis sp. from a Chilean lake. Syst Appl Microbiol. 2000 Jun;23(2):191-7. PMID: 10930070.

"

LKT C9600 Cyanopeptolin 1007 50 µg 606.7 Toxin produced by Microcystis; serine protease inhibitor. CYP 1007 791104-89-7 ≥95% 1007.14 C49H70N10O13 Blue Ice -20°C "Silva-Stenico ME, Rigonato J, Leal MG, et al. Non-ribosomal halogenated protease inhibitors from cyanobacterial isolates as attractive drug targets. Curr Med Chem. 2012;19(30):5205-13. PMID: 22934766.

Gademann K, Portmann C, Blom JF, et al. Multiple toxin production in the cyanobacterium microcystis: isolation of the toxic protease inhibitor cyanopeptolin 1020. J Nat Prod. 2010 May 28;73(5):980-4. PMID: 20405925.

Choi H, Oh SK, Yih W, et al. Cyanopeptoline CB071: a cyclic depsipeptide isolated from the freshwater cyanobacterium Aphanocapsa sp. Chem Pharm Bull (Tokyo). 2008 Aug;56(8):1191-3. PMID: 18670126.

von Elert E, Oberer L, Merkel P, et al. Cyanopeptolin 954, a chlorine-containing chymotrypsin inhibitor of Microcystis aeruginosa NIVA Cya 43. J Nat Prod. 2005 Sep;68(9):1324-7. PMID: 16180807.

Neumann U, Campos V, Cantarero S, et al. Co-occurrence of non-toxic (cyanopeptolin) and toxic (microcystin) peptides in a bloom of Microcystis sp. from a Chilean lake. Syst Appl Microbiol. 2000 Jun;23(2):191-7. PMID: 10930070.

"

LKT M3410 Microcystin (N-Me)-LR 25 µg 543.6 Cyclic heptapeptide produced by Microcystis; PP1/2A inhibitor, potential GSK-3β activator. MC(N-Me)LR 1865776-22-2 ≥95% 1009.3 C50H76N10O12 Blue Ice -20°C "Zhou Y, Chen Y, Yuan M, et al. In vivo study on the effects of microcystin-LR on the apoptosis, proliferation and differentiation of rat testicular spermatogenic cells of male rats injected i.p. with toxins. J Toxicol Sci. 2013;38(5):661-70. PMID: 24025782.

Sun Y, Liu JH, Huang P, et al. Alterations of tau and VASP during microcystin-LR-induced cytoskeletal reorganization in a human liver cell line. Environ Toxicol. 2013 Aug 9. doi:. [Epub ahead of print]. PMID: 23929704.

Zhang H, Cai C, Fang W, et al. Oxidative damage and apoptosis induced by microcystin-LR in the liver of Rana nigromaculata in vivo. Aquat Toxicol. 2013 Sep 15;140-141:11-8. PMID: 23747548.

Wang J, Lin F, Cai F, et al. Microcystin-LR inhibited hippocampal long-term potential via regulation of the glycogen synthase kinase-3β pathway. Chemosphere. 2013 Sep;93(2):223-9. PMID: 23701903.

Liang J, Li T, Zhang YL, etal. Effect of microcystin-LR on protein phosphatase 2A and its function in human amniotic epithelial cells. J Zhejiang Univ Sci B. 2011 Dec;12(12):951-60. PMID: 22135143.

Gan N, Sun X, Song L. Activation of Nrf2 by microcystin-LR provides advantages for liver cancer cell growth. Chem Res Toxicol. 2010 Sep 20;23(9):1477-84. PMID: 20722399.

" "UN number: 3462     Class:  6.1     Packing group I

Proper shipping name:  Toxins, extracted from living sources, solid, n.o.s. (Microcystin (N-Me)-LR)"

LKT M3408 [D-Asp3]-Microcystin-LR 25 µg 199 Cyclic heptapeptide produced by Microcystis; PP1/2A inhibitor, potential GSK-3β activator. desmethyl microcystin LR, Asp3-MCLR; Microcystin LR, desmethyl ("Asp3-MCLR") 120011-66-7 ≥95% 981.2 C48H72N10O12 CC1C(NC(=O)C(NC(=O)CC(NC(=O)C(NC(=O)C(NC(=O)C(=C)N(C(=O)CCC(NC1=O)C(=O)O)C)C)CC(C)C)C(=O)O)CCCN=C(N)N)C=CC(=CC(C)C(CC2=CC=CC=C2)OC)C Blue Ice -20°C "Zhou Y, Chen Y, Yuan M, et al. In vivo study on the effects of microcystin-LR on the apoptosis, proliferation and differentiation of rat testicular spermatogenic cells of male rats injected i.p. with toxins. J Toxicol Sci. 2013;38(5):661-70. PMID: 24025782.

Sun Y, Liu JH, Huang P, et al. Alterations of tau and VASP during microcystin-LR-induced cytoskeletal reorganization in a human liver cell line. Environ Toxicol. 2013 Aug 9. doi:. [Epub ahead of print]. PMID: 23929704.

Zhang H, Cai C, Fang W, et al. Oxidative damage and apoptosis induced by microcystin-LR in the liver of Rana nigromaculata in vivo. Aquat Toxicol. 2013 Sep 15;140-141:11-8. PMID: 23747548.

Wang J, Lin F, Cai F, et al. Microcystin-LR inhibited hippocampal long-term potential via regulation of the glycogen synthase kinase-3β pathway. Chemosphere. 2013 Sep;93(2):223-9. PMID: 23701903.

Liang J, Li T, Zhang YL, etal. Effect of microcystin-LR on protein phosphatase 2A and its function in human amniotic epithelial cells. J Zhejiang Univ Sci B. 2011 Dec;12(12):951-60. PMID: 22135143.

Gan N, Sun X, Song L. Activation of Nrf2 by microcystin-LR provides advantages for liver cancer cell growth. Chem Res Toxicol. 2010 Sep 20;23(9):1477-84. PMID: 20722399.

" "UN number: 3462     Class:  6.1     Packing group:  I

Proper shipping name:  Toxins, extracted from living sources, solid, n.o.s. ([D-Asp3]-Microcystin-LR)"

LKT M3212 Microginin 704 50 µg 606.7 Found in Microcystis; protein phosphatase, ACE, leucine aminopeptidase inhibitor. ≥95% 704.87 C35H52N4O9S Blue Ice -20°C "Schatz D, Keren Y, Vardi A, et al. Towards clarification of the biological role of microcystins, a family of cyanobacterial toxins. Environ Microbiol. 2007 Apr;9(4):965-70. PMID: 17359268.

Kraft M, Schleberger C, Weckesser J, et al. Binding structure of the leucine aminopeptidase inhibitor microginin FR1. FEBS Lett. 2006 Dec 22;580(30):6943-7. PMID: 17157838.

Runnage ME, Burke AJ, Davies SG, et al. Asymmetric Synthesis of the N-terminal component of Microginin: (2S,3R)-3-Amino-2-Hydroxydecanoic Acid, its (2R,3R)-Epimer and (3R)-3-Aminodecanoic Acid. Tetrahedron: Asymmetry. 1995;6(1):165-176. 

"

LKT M3210 Microginin 690 100 µg 509.7 Found in Microcystis; protein phosphatase, ACE, leucine aminopeptidase inhibitor. 958961-34-7 ≥95% 690.85 C34H50N4O9S CCCCCCCC(C(C(=O)N(C)C(CCS(=O)C)C(=O)NC(CC1=CC=C(C=C1)O)C(=O)NC(CC2=CC=C(C=C2)O)C(=O)O)O)N Blue Ice -20°C "Schatz D, Keren Y, Vardi A, et al. Towards clarification of the biological role of microcystins, a family of cyanobacterial toxins. Environ Microbiol. 2007 Apr;9(4):965-70. PMID: 17359268.

Kraft M, Schleberger C, Weckesser J, et al. Binding structure of the leucine aminopeptidase inhibitor microginin FR1. FEBS Lett. 2006 Dec 22;580(30):6943-7. PMID: 17157838.

Runnage ME, Burke AJ, Davies SG, et al. Asymmetric Synthesis of the N-terminal component of Microginin: (2S,3R)-3-Amino-2-Hydroxydecanoic Acid, its (2R,3R)-Epimer and (3R)-3-Aminodecanoic Acid. Tetrahedron: Asymmetry. 1995;6(1):165-176. 

"

LKT M3208 Microginin 527 50 µg 606.7 Found in Microcystis; protein phosphatase, ACE, leucine aminopeptidase inhibitor. 1135249-50-1 ≥95% 527.67 C25H41N3O7S CCCCCCCC(C(C(=O)N(C)C(CCS(=O)C)C(=O)NC(CC1=CC=C(C=C1)O)C(=O)O)O)N Blue Ice -20°C "Schatz D, Keren Y, Vardi A, et al. Towards clarification of the biological role of microcystins, a family of cyanobacterial toxins. Environ Microbiol. 2007 Apr;9(4):965-70. PMID: 17359268.

Kraft M, Schleberger C, Weckesser J, et al. Binding structure of the leucine aminopeptidase inhibitor microginin FR1. FEBS Lett. 2006 Dec 22;580(30):6943-7. PMID: 17157838.

Runnage ME, Burke AJ, Davies SG, et al. Asymmetric Synthesis of the N-terminal component of Microginin: (2S,3R)-3-Amino-2-Hydroxydecanoic Acid, its (2R,3R)-Epimer and (3R)-3-Aminodecanoic Acid. Tetrahedron: Asymmetry. 1995;6(1):165-176. 

"

LKT B6918 Brevetoxin 3 100 µg 271.7 Polyether neurotoxin found in Karenia brevis; Nav1.4/1.5 Na+ channel activator. PbTx-3 85079-48-7 ≥95% 897.2 C50H72O14 CC1CC2C(CC3(C(O2)CC4C(O3)C(=CC(=O)O4)C)C)OC5C1OC6CC7C(CC8C(O7)(CC=CC9C(O8)CC1C(O9)CC2C(O1)(C(CC(O2)CC(=C)CO)O)C)C)(OC6(CC5)C)C Ambient -20°C Soluble in acetone, ethyl acetate, ethanol, and methanol. "Zaias J, Fleming LE, Baden DG, et al. Repeated exposure to aerosolized brevetoxin-3 induces prolonged airway hyperresponsiveness and lung inflammation in sheep. Inhal Toxicol. 2011 Mar;23(4):205-11. PMID: 21456953.

Liberona JL, Cárdenas JC, Reyes R, et al. Sodium-dependent action potentials induced by brevetoxin-3 trigger both IP3 increase and intracellular Ca2+ release in rat skeletal myotubes. Cell Calcium. 2008 Sep;44(3):289-97. PMID: 18276006.

Cao Z, George J, Baden DG, et al. Brevetoxin-induced phosphorylation of Pyk2 and Src in murine neocortical neurons involves distinct signaling pathways. Brain Res. 2007 Dec 12;1184:17-27. PMID: 17963734.

Radwan FF, Ramsdell JS. Characterization of in vitro oxidative and conjugative metabolic pathways for brevetoxin (PbTx-2). Toxicol Sci. 2006 Jan;89(1):57-65. PMID: 16221966.

Colman JR, Ramsdell JS. The type B brevetoxin (PbTx-3) adversely affects development, cardiovascular function, and survival in Medaka (Oryzias latipes) embryos. Environ Health Perspect. 2003 Dec;111(16):1920-5. PMID: 14644667.

Bottein Dechraoui MY, Ramsdell JS. Type B brevetoxins show tissue selectivity for voltage-gated sodium channels: comparison of brain, skeletal muscle and cardiac sodium channels. Toxicon. 2003 Jun;41(7):919-27. PMID: 12782093.

Berman FW, Murray TF. Brevetoxins cause acute excitotoxicity in primary cultures of rat cerebellar granule neurons. J Pharmacol Exp Ther. 1999 Jul;290(1):439-44. PMID: 10381810.

Jeglitsch G, Rein K, Baden DG, et al. Brevetoxin-3 (PbTx-3) and its derivatives modulate single tetrodotoxin-sensitive sodium channels in rat sensory neurons. J Pharmacol Exp Ther. 1998 Feb;284(2):516-25. PMID: 9454792.

" "UN number: 3462     Class: 6.1     Packing Group: II

Proper shipping name: Toxins, extracted from living sources, solid, n.o.s. (Brevetoxin 3)"

LKT B6917 Brevetoxin 2 100 µg 198.5 Polyether neurotoxin found in Karenia brevis; Nav1.4/1.5 Na+ channel activator. PbTx-2 79580-28-2 ≥95% 895.2 C50H70O14 CC1CC2C(CC3(C(O2)CC4C(O3)C(=CC(=O)O4)C)C)OC5C1OC6CC7C(CC8C(O7)(CC=CC9C(O8)CC1C(O9)CC2C(O1)(C(CC(O2)CC(=C)C=O)O)C)C)(OC6(CC5)C)C Ambient -20°C "Zaias J, Fleming LE, Baden DG, et al. Repeated exposure to aerosolized brevetoxin-3 induces prolonged airway hyperresponsiveness and lung inflammation in sheep. Inhal Toxicol. 2011 Mar;23(4):205-11. PMID: 21456953.

Liberona JL, Cárdenas JC, Reyes R, et al. Sodium-dependent action potentials induced by brevetoxin-3 trigger both IP3 increase and intracellular Ca2+ release in rat skeletal myotubes. Cell Calcium. 2008 Sep;44(3):289-97. PMID: 18276006.

Radwan FF, Ramsdell JS. Brevetoxin forms covalent DNA adducts in rat lung following intratracheal exposure. Environ Health Perspect. 2008 Jul;116(7):930-6. PMID: 18629316.

Cao Z, George J, Baden DG, et al. Brevetoxin-induced phosphorylation of Pyk2 and Src in murine neocortical neurons involves distinct signaling pathways. Brain Res. 2007 Dec 12;1184:17-27. PMID: 17963734.

Bottein Dechraoui MY, Ramsdell JS. Type B brevetoxins show tissue selectivity for voltage-gated sodium channels: comparison of brain, skeletal muscle and cardiac sodium channels. Toxicon. 2003 Jun;41(7):919-27. PMID: 12782093.

Berman FW, Murray TF. Brevetoxins cause acute excitotoxicity in primary cultures of rat cerebellar granule neurons. J Pharmacol Exp Ther. 1999 Jul;290(1):439-44. PMID: 10381810.

" "UN Number: 3462     Class: 6.1     Packing Group: II

Proper Shipping Name:  Toxins, extracted from living sources, solid, n.o.s. (Brevetoxin 2) "

LKT C0255 Cantharidin 25 mg 70.4 Toxin produced by Canarthis vesicatoria; PP1/2A inhibitor. 56-25-7 ≥98% 196.2 C10H12O4 CC12C3CCC(C1(C(=O)OC2=O)C)O3 Ambient Ambient "Chen X, Liu J, Zhang Y. Cantharidin impedes the activity of protein serine/threonine phosphatase in Plutella xylostella. Mol Biosyst. 2013 Nov 19. [Epub ahead of print]. PMID: 24253262.

Kadioglu O, Kermani NS, Kelter G, et al. Pharmacogenomics of Cantharidin in Tumor Cells. Biochem Pharmacol. 2013 Nov 11. pii: S0006-2952(13)00709-0. Epub ahead of print]. PMID: 24231507.

Kim JA, Kim Y, Kwon BM, et al. The natural compound cantharidin induces cancer cell death through inhibition of heat shock protein 70 (HSP70) and Bcl-2-associated athanogene domain 3 (BAG3) expression by blocking heat shock factor 1 (HSF1) binding to promoters. J Biol Chem. 2013 Oct 4;288(40):28713-26. PMID: 23983126.

Ivetic Tkalcevic V, Hrvacic B, Bosnar M, et al. Cantharidin-induced inflammation in mouse ear model for translational research of novel anti-inflammatories. Transl Res. 2012 Aug;160(2):137-45. PMID: 22677362.

Kim MH, Shim KS, Kim SH. Inhibitory effect of cantharidin on osteoclast differentiation and bone resorption. Arch Pharm Res. 2010 Mar;33(3):457-62. PMID: 20361312.

" T+, Xi "UN number: 2811     Class: 6.1     Packing Group: I

Proper shipping name: Toxic solid, organic, n.o.s. (Cantharidin)"

LKT C0255 Cantharidin 100 mg 206.3 Toxin produced by Canarthis vesicatoria; PP1/2A inhibitor. 56-25-7 ≥98% 196.2 C10H12O4 CC12C3CCC(C1(C(=O)OC2=O)C)O3 Ambient Ambient "Chen X, Liu J, Zhang Y. Cantharidin impedes the activity of protein serine/threonine phosphatase in Plutella xylostella. Mol Biosyst. 2013 Nov 19. [Epub ahead of print]. PMID: 24253262.

Kadioglu O, Kermani NS, Kelter G, et al. Pharmacogenomics of Cantharidin in Tumor Cells. Biochem Pharmacol. 2013 Nov 11. pii: S0006-2952(13)00709-0. Epub ahead of print]. PMID: 24231507.

Kim JA, Kim Y, Kwon BM, et al. The natural compound cantharidin induces cancer cell death through inhibition of heat shock protein 70 (HSP70) and Bcl-2-associated athanogene domain 3 (BAG3) expression by blocking heat shock factor 1 (HSF1) binding to promoters. J Biol Chem. 2013 Oct 4;288(40):28713-26. PMID: 23983126.

Ivetic Tkalcevic V, Hrvacic B, Bosnar M, et al. Cantharidin-induced inflammation in mouse ear model for translational research of novel anti-inflammatories. Transl Res. 2012 Aug;160(2):137-45. PMID: 22677362.

Kim MH, Shim KS, Kim SH. Inhibitory effect of cantharidin on osteoclast differentiation and bone resorption. Arch Pharm Res. 2010 Mar;33(3):457-62. PMID: 20361312.

" T+, Xi "UN number: 2811     Class: 6.1     Packing Group: I

Proper shipping name: Toxic solid, organic, n.o.s. (Cantharidin)"

LKT C0255 Cantharidin 500 mg 752.3 Toxin produced by Canarthis vesicatoria; PP1/2A inhibitor. 56-25-7 ≥98% 196.2 C10H12O4 CC12C3CCC(C1(C(=O)OC2=O)C)O3 Ambient Ambient "Chen X, Liu J, Zhang Y. Cantharidin impedes the activity of protein serine/threonine phosphatase in Plutella xylostella. Mol Biosyst. 2013 Nov 19. [Epub ahead of print]. PMID: 24253262.

Kadioglu O, Kermani NS, Kelter G, et al. Pharmacogenomics of Cantharidin in Tumor Cells. Biochem Pharmacol. 2013 Nov 11. pii: S0006-2952(13)00709-0. Epub ahead of print]. PMID: 24231507.

Kim JA, Kim Y, Kwon BM, et al. The natural compound cantharidin induces cancer cell death through inhibition of heat shock protein 70 (HSP70) and Bcl-2-associated athanogene domain 3 (BAG3) expression by blocking heat shock factor 1 (HSF1) binding to promoters. J Biol Chem. 2013 Oct 4;288(40):28713-26. PMID: 23983126.

Ivetic Tkalcevic V, Hrvacic B, Bosnar M, et al. Cantharidin-induced inflammation in mouse ear model for translational research of novel anti-inflammatories. Transl Res. 2012 Aug;160(2):137-45. PMID: 22677362.

Kim MH, Shim KS, Kim SH. Inhibitory effect of cantharidin on osteoclast differentiation and bone resorption. Arch Pharm Res. 2010 Mar;33(3):457-62. PMID: 20361312.

" T+, Xi "UN number: 2811     Class: 6.1     Packing Group: I

Proper shipping name: Toxic solid, organic, n.o.s. (Cantharidin)"

LKT N1755 Neomycin Sulfate 1 g 18.3 Polycationic aminoglycoside; protein translation inhibitor, cation channel/receptor (P2X, TRPV1) blocker. 1405-10-3 ≥98% 908.9 C23H46N6O13 3H2SO4 C1C(C(C(C(C1N)OC2C(C(C(C(O2)CN)O)O)N)OC3C(C(C(O3)CO)OC4C(C(C(C(O4)CN)O)O)N)O)O)N.OS(=O)(=O)O.OS(=O)(=O)O.OS(=O)(=O)O Ambient Ambient Soluble in water (1 g/mL). "Wang L, Pulk A, Wasserman MR, et al. Allosteric control of the ribosome by small-molecule antibiotics. Nat Struct Mol Biol. 2012 Sep;19(9):957-63. PMID: 22902368.

Bongartz EV, Rettinger J, Hausmann R. Aminoglycoside block of P2X2 receptors heterologously expressed in Xenopus laevis oocytes. Purinergic Signal. 2010 Dec;6(4):393-403. PMID: 21437010.

Aukema KG, Chohan KK, Plourde GL, et al. Small molecule inhibitors of yeast pre-mRNA splicing. ACS Chem Biol. 2009 Sep 18;4(9):759-68. PMID: 19634919.

Anupam R, Denapoli L, Muchenditsi A, et al. Identification of neomycin B-binding site in T box antiterminator model RNA. Bioorg Med Chem. 2008 Apr 15;16(8):4466-70. PMID: 18329274.

Kawamoto SA, Sudhahar CG, Hatfield CL, et al. Studies on the mechanism of inhibition of bacterial ribonuclease P by aminoglycoside derivatives. Nucleic Acids Res. 2008 Feb;36(2):697-704. PMID: 18084035.

Raisinghani M, Premkumar LS. Block of native and cloned vanilloid receptor 1 (TRPV1) by aminoglycoside antibiotics. Pain. 2005 Jan;113(1-2):123-33. PMID: 15621372.

Wright JM, Collier B. The effects of neomycin upon transmitter release and action. J Pharmacol Exp Ther. 1977 Mar;200(3):576-87. PMID: 191590.

" Xn Not dangerous goods.

LKT N1755 Neomycin Sulfate 5 g 23.8 Polycationic aminoglycoside; protein translation inhibitor, cation channel/receptor (P2X, TRPV1) blocker. 1405-10-3 ≥98% 908.9 C23H46N6O13 3H2SO4 C1C(C(C(C(C1N)OC2C(C(C(C(O2)CN)O)O)N)OC3C(C(C(O3)CO)OC4C(C(C(C(O4)CN)O)O)N)O)O)N.OS(=O)(=O)O.OS(=O)(=O)O.OS(=O)(=O)O Ambient Ambient Soluble in water (1 g/mL). "Wang L, Pulk A, Wasserman MR, et al. Allosteric control of the ribosome by small-molecule antibiotics. Nat Struct Mol Biol. 2012 Sep;19(9):957-63. PMID: 22902368.

Bongartz EV, Rettinger J, Hausmann R. Aminoglycoside block of P2X2 receptors heterologously expressed in Xenopus laevis oocytes. Purinergic Signal. 2010 Dec;6(4):393-403. PMID: 21437010.

Aukema KG, Chohan KK, Plourde GL, et al. Small molecule inhibitors of yeast pre-mRNA splicing. ACS Chem Biol. 2009 Sep 18;4(9):759-68. PMID: 19634919.

Anupam R, Denapoli L, Muchenditsi A, et al. Identification of neomycin B-binding site in T box antiterminator model RNA. Bioorg Med Chem. 2008 Apr 15;16(8):4466-70. PMID: 18329274.

Kawamoto SA, Sudhahar CG, Hatfield CL, et al. Studies on the mechanism of inhibition of bacterial ribonuclease P by aminoglycoside derivatives. Nucleic Acids Res. 2008 Feb;36(2):697-704. PMID: 18084035.

Raisinghani M, Premkumar LS. Block of native and cloned vanilloid receptor 1 (TRPV1) by aminoglycoside antibiotics. Pain. 2005 Jan;113(1-2):123-33. PMID: 15621372.

Wright JM, Collier B. The effects of neomycin upon transmitter release and action. J Pharmacol Exp Ther. 1977 Mar;200(3):576-87. PMID: 191590.

" Xn Not dangerous goods.

LKT N1755 Neomycin Sulfate 10 g 27.3 Polycationic aminoglycoside; protein translation inhibitor, cation channel/receptor (P2X, TRPV1) blocker. 1405-10-3 ≥98% 908.9 C23H46N6O13 3H2SO4 C1C(C(C(C(C1N)OC2C(C(C(C(O2)CN)O)O)N)OC3C(C(C(O3)CO)OC4C(C(C(C(O4)CN)O)O)N)O)O)N.OS(=O)(=O)O.OS(=O)(=O)O.OS(=O)(=O)O Ambient Ambient Soluble in water (1 g/mL). "Wang L, Pulk A, Wasserman MR, et al. Allosteric control of the ribosome by small-molecule antibiotics. Nat Struct Mol Biol. 2012 Sep;19(9):957-63. PMID: 22902368.

Bongartz EV, Rettinger J, Hausmann R. Aminoglycoside block of P2X2 receptors heterologously expressed in Xenopus laevis oocytes. Purinergic Signal. 2010 Dec;6(4):393-403. PMID: 21437010.

Aukema KG, Chohan KK, Plourde GL, et al. Small molecule inhibitors of yeast pre-mRNA splicing. ACS Chem Biol. 2009 Sep 18;4(9):759-68. PMID: 19634919.

Anupam R, Denapoli L, Muchenditsi A, et al. Identification of neomycin B-binding site in T box antiterminator model RNA. Bioorg Med Chem. 2008 Apr 15;16(8):4466-70. PMID: 18329274.

Kawamoto SA, Sudhahar CG, Hatfield CL, et al. Studies on the mechanism of inhibition of bacterial ribonuclease P by aminoglycoside derivatives. Nucleic Acids Res. 2008 Feb;36(2):697-704. PMID: 18084035.

Raisinghani M, Premkumar LS. Block of native and cloned vanilloid receptor 1 (TRPV1) by aminoglycoside antibiotics. Pain. 2005 Jan;113(1-2):123-33. PMID: 15621372.

Wright JM, Collier B. The effects of neomycin upon transmitter release and action. J Pharmacol Exp Ther. 1977 Mar;200(3):576-87. PMID: 191590.

" Xn Not dangerous goods.

LKT N1755 Neomycin Sulfate 25 g 55 Polycationic aminoglycoside; protein translation inhibitor, cation channel/receptor (P2X, TRPV1) blocker. 1405-10-3 ≥98% 908.9 C23H46N6O13 3H2SO4 C1C(C(C(C(C1N)OC2C(C(C(C(O2)CN)O)O)N)OC3C(C(C(O3)CO)OC4C(C(C(C(O4)CN)O)O)N)O)O)N.OS(=O)(=O)O.OS(=O)(=O)O.OS(=O)(=O)O Ambient Ambient Soluble in water (1 g/mL). "Wang L, Pulk A, Wasserman MR, et al. Allosteric control of the ribosome by small-molecule antibiotics. Nat Struct Mol Biol. 2012 Sep;19(9):957-63. PMID: 22902368.

Bongartz EV, Rettinger J, Hausmann R. Aminoglycoside block of P2X2 receptors heterologously expressed in Xenopus laevis oocytes. Purinergic Signal. 2010 Dec;6(4):393-403. PMID: 21437010.

Aukema KG, Chohan KK, Plourde GL, et al. Small molecule inhibitors of yeast pre-mRNA splicing. ACS Chem Biol. 2009 Sep 18;4(9):759-68. PMID: 19634919.

Anupam R, Denapoli L, Muchenditsi A, et al. Identification of neomycin B-binding site in T box antiterminator model RNA. Bioorg Med Chem. 2008 Apr 15;16(8):4466-70. PMID: 18329274.

Kawamoto SA, Sudhahar CG, Hatfield CL, et al. Studies on the mechanism of inhibition of bacterial ribonuclease P by aminoglycoside derivatives. Nucleic Acids Res. 2008 Feb;36(2):697-704. PMID: 18084035.

Raisinghani M, Premkumar LS. Block of native and cloned vanilloid receptor 1 (TRPV1) by aminoglycoside antibiotics. Pain. 2005 Jan;113(1-2):123-33. PMID: 15621372.

Wright JM, Collier B. The effects of neomycin upon transmitter release and action. J Pharmacol Exp Ther. 1977 Mar;200(3):576-87. PMID: 191590.

" Xn Not dangerous goods.

LKT R0154 Ranolazine Dihydrochloride 100 mg 163.2 Nav1.7 and Nav1.8 N1+ channel blocker. N-(2,6-Dimethylphenyl)-4-[2-hydroxy-3-(2-methoxyphenoxy)propyl]-1-piperazineacetamide dihydrochloride RS-43285 95635-56-6 ≥98% 500.47 C24H33N3O4 2HCl CC1=C(C(=CC=C1)C)NC(=O)CN2CCN(CC2)CC(COC3=CC=CC=C3OC)O.Cl.Cl Ambient Ambient Soluble in water. "Tocchetti CG, Carpi A, Coppola C, et al. Ranolazine protects from doxorubicin-induced oxidative stress and cardiac dysfunction. Eur J Heart Fail. 2014 Jan 6. [Epub ahead of print]. PMID: 24464789.

Aldakkak M, Stowe DF, Camara AK. Safety and Efficacy of Ranolazine for the Treatment of Chronic Angina Pectoris. Clin Med Insights Ther. 2013 Jan 15;2013(5):1-14. PMID: 24574825.

Aidonidis I, Doulas K, Hatziefthimiou A, et al. Ranolazine-induced postrepolarization refractoriness suppresses induction of atrial flutter and fibrillation in anesthetized rabbits. J Cardiovasc Pharmacol Ther. 2013 Jan;18(1):94-101. PMID: 22872232.

" None Not dangerous goods.

LKT R0154 Ranolazine Dihydrochloride 500 mg 502.8 Nav1.7 and Nav1.8 N1+ channel blocker. N-(2,6-Dimethylphenyl)-4-[2-hydroxy-3-(2-methoxyphenoxy)propyl]-1-piperazineacetamide dihydrochloride RS-43285 95635-56-6 ≥98% 500.47 C24H33N3O4 2HCl CC1=C(C(=CC=C1)C)NC(=O)CN2CCN(CC2)CC(COC3=CC=CC=C3OC)O.Cl.Cl Ambient Ambient Soluble in water. "Tocchetti CG, Carpi A, Coppola C, et al. Ranolazine protects from doxorubicin-induced oxidative stress and cardiac dysfunction. Eur J Heart Fail. 2014 Jan 6. [Epub ahead of print]. PMID: 24464789.

Aldakkak M, Stowe DF, Camara AK. Safety and Efficacy of Ranolazine for the Treatment of Chronic Angina Pectoris. Clin Med Insights Ther. 2013 Jan 15;2013(5):1-14. PMID: 24574825.

Aidonidis I, Doulas K, Hatziefthimiou A, et al. Ranolazine-induced postrepolarization refractoriness suppresses induction of atrial flutter and fibrillation in anesthetized rabbits. J Cardiovasc Pharmacol Ther. 2013 Jan;18(1):94-101. PMID: 22872232.

" None Not dangerous goods.

LKT R0154 Ranolazine Dihydrochloride 1 g 788.2 Nav1.7 and Nav1.8 N1+ channel blocker. N-(2,6-Dimethylphenyl)-4-[2-hydroxy-3-(2-methoxyphenoxy)propyl]-1-piperazineacetamide dihydrochloride RS-43285 95635-56-6 ≥98% 500.47 C24H33N3O4 2HCl CC1=C(C(=CC=C1)C)NC(=O)CN2CCN(CC2)CC(COC3=CC=CC=C3OC)O.Cl.Cl Ambient Ambient Soluble in water. "Tocchetti CG, Carpi A, Coppola C, et al. Ranolazine protects from doxorubicin-induced oxidative stress and cardiac dysfunction. Eur J Heart Fail. 2014 Jan 6. [Epub ahead of print]. PMID: 24464789.

Aldakkak M, Stowe DF, Camara AK. Safety and Efficacy of Ranolazine for the Treatment of Chronic Angina Pectoris. Clin Med Insights Ther. 2013 Jan 15;2013(5):1-14. PMID: 24574825.

Aidonidis I, Doulas K, Hatziefthimiou A, et al. Ranolazine-induced postrepolarization refractoriness suppresses induction of atrial flutter and fibrillation in anesthetized rabbits. J Cardiovasc Pharmacol Ther. 2013 Jan;18(1):94-101. PMID: 22872232.

" None Not dangerous goods.

LKT P2522 S-(N-Phenylthiocarbamoyl)-glutathione 5 mg 251.3 Glutathione-ITC conjugate, antioxidant. Phenylisothiocyanate glutathione ≥98% 442.51 C17H22N4O6S2 Ambient -20°C "Martelli A, Testai L, Citi V, et al. Pharmacological characterization of the vascular effects of aryl isothiocyanates: Is hydrogen sulfide the real player? Vascul Pharmacol. 2013 Nov 25. pii: S1537-1891(13)00138-9. PMID: 24287004.

Abreu AC, Borges A, Simões LC, et al. Antibacterial activity of phenyl isothiocyanate on Escherichia coli and Staphylococcus aureus. Med Chem. 2013 Aug;9(5):756-61. PMID: 22974327.

Schroeder NE, Macguidwin AE. Mortality and behavior in Heterodera glycines juveniles following exposure to isothiocyanate compounds. J Nematol. 2010 Sep;42(3):194-200. PMID: 22736856.

Beevi SS, Mangamoori LN, Dhand V, et al. Isothiocyanate profile and selective antibacterial activity of root, stem, and leaf extracts derived from Raphanus sativus L. Foodborne Pathog Dis. 2009 Jan-Feb;6(1):129-36. PMID: 19182965.

Thejass P, Kuttan G. Inhibition of endothelial cell differentiation and proinflammatory cytokine production during angiogenesis by allyl isothiocyanate and phenyl isothiocyanate. Integr Cancer Ther. 2007 Dec;6(4):389-99. PMID: 18048887.

Thejass P, Kuttan G. Allyl isothiocyanate (AITC) and phenyl isothiocyanate (PITC) inhibit tumour-specific angiogenesis by downregulating nitric oxide (NO) and tumour necrosis factor-alpha (TNF-alpha) production. Nitric Oxide. 2007 Mar;16(2):247-57. PMID: 17097904.

Manesh C, Kuttan G. Effect of naturally occurring isothiocyanates on the immune system. Immunopharmacol Immunotoxicol. 2003 Aug;25(3):451-9. PMID: 19180807.

Manesh C, Kuttan G. Anti-tumour and anti-oxidant activity of naturally occurring isothiocyanates. J Exp Clin Cancer Res. 2003 Jun;22(2):193-9. PMID: 12866569.

" Not dangerous goods.

LKT P2522 S-(N-Phenylthiocarbamoyl)-glutathione 10 mg 502.3 Glutathione-ITC conjugate, antioxidant. Phenylisothiocyanate glutathione ≥98% 442.51 C17H22N4O6S2 Ambient -20°C "Martelli A, Testai L, Citi V, et al. Pharmacological characterization of the vascular effects of aryl isothiocyanates: Is hydrogen sulfide the real player? Vascul Pharmacol. 2013 Nov 25. pii: S1537-1891(13)00138-9. PMID: 24287004.

Abreu AC, Borges A, Simões LC, et al. Antibacterial activity of phenyl isothiocyanate on Escherichia coli and Staphylococcus aureus. Med Chem. 2013 Aug;9(5):756-61. PMID: 22974327.

Schroeder NE, Macguidwin AE. Mortality and behavior in Heterodera glycines juveniles following exposure to isothiocyanate compounds. J Nematol. 2010 Sep;42(3):194-200. PMID: 22736856.

Beevi SS, Mangamoori LN, Dhand V, et al. Isothiocyanate profile and selective antibacterial activity of root, stem, and leaf extracts derived from Raphanus sativus L. Foodborne Pathog Dis. 2009 Jan-Feb;6(1):129-36. PMID: 19182965.

Thejass P, Kuttan G. Inhibition of endothelial cell differentiation and proinflammatory cytokine production during angiogenesis by allyl isothiocyanate and phenyl isothiocyanate. Integr Cancer Ther. 2007 Dec;6(4):389-99. PMID: 18048887.

Thejass P, Kuttan G. Allyl isothiocyanate (AITC) and phenyl isothiocyanate (PITC) inhibit tumour-specific angiogenesis by downregulating nitric oxide (NO) and tumour necrosis factor-alpha (TNF-alpha) production. Nitric Oxide. 2007 Mar;16(2):247-57. PMID: 17097904.

Manesh C, Kuttan G. Effect of naturally occurring isothiocyanates on the immune system. Immunopharmacol Immunotoxicol. 2003 Aug;25(3):451-9. PMID: 19180807.

Manesh C, Kuttan G. Anti-tumour and anti-oxidant activity of naturally occurring isothiocyanates. J Exp Clin Cancer Res. 2003 Jun;22(2):193-9. PMID: 12866569.

" Not dangerous goods.

LKT P2522 S-(N-Phenylthiocarbamoyl)-glutathione 25 mg 1004.5 Glutathione-ITC conjugate, antioxidant. Phenylisothiocyanate glutathione ≥98% 442.51 C17H22N4O6S2 Ambient -20°C "Martelli A, Testai L, Citi V, et al. Pharmacological characterization of the vascular effects of aryl isothiocyanates: Is hydrogen sulfide the real player? Vascul Pharmacol. 2013 Nov 25. pii: S1537-1891(13)00138-9. PMID: 24287004.

Abreu AC, Borges A, Simões LC, et al. Antibacterial activity of phenyl isothiocyanate on Escherichia coli and Staphylococcus aureus. Med Chem. 2013 Aug;9(5):756-61. PMID: 22974327.

Schroeder NE, Macguidwin AE. Mortality and behavior in Heterodera glycines juveniles following exposure to isothiocyanate compounds. J Nematol. 2010 Sep;42(3):194-200. PMID: 22736856.

Beevi SS, Mangamoori LN, Dhand V, et al. Isothiocyanate profile and selective antibacterial activity of root, stem, and leaf extracts derived from Raphanus sativus L. Foodborne Pathog Dis. 2009 Jan-Feb;6(1):129-36. PMID: 19182965.

Thejass P, Kuttan G. Inhibition of endothelial cell differentiation and proinflammatory cytokine production during angiogenesis by allyl isothiocyanate and phenyl isothiocyanate. Integr Cancer Ther. 2007 Dec;6(4):389-99. PMID: 18048887.

Thejass P, Kuttan G. Allyl isothiocyanate (AITC) and phenyl isothiocyanate (PITC) inhibit tumour-specific angiogenesis by downregulating nitric oxide (NO) and tumour necrosis factor-alpha (TNF-alpha) production. Nitric Oxide. 2007 Mar;16(2):247-57. PMID: 17097904.

Manesh C, Kuttan G. Effect of naturally occurring isothiocyanates on the immune system. Immunopharmacol Immunotoxicol. 2003 Aug;25(3):451-9. PMID: 19180807.

Manesh C, Kuttan G. Anti-tumour and anti-oxidant activity of naturally occurring isothiocyanates. J Exp Clin Cancer Res. 2003 Jun;22(2):193-9. PMID: 12866569.

" Not dangerous goods.

LKT P2516 S-(N-Phenylbutylthiocarbamoyl)-L-cysteine 10 mg 142.4 Cysteine-ITC conjugate, antioxidant. Phenylbutylisothiocyanate-L-cysteine ≥98% 312.45 C14H20N2O2S2 Ambient -20°C "Son HY, Nishikawa A, Furukawa F, et al. Modifying effects of 4-phenylbutyl isothiocyanate on N-nitrosobis(2-oxopropyl)amine-induced tumorigenesis in hamsters. Cancer Lett. 2000 Nov 28;160(2):141-7. PMID: 11053643.

Yu R, Mandlekar S, Harvey KJ, et al. Chemopreventive isothiocyanates induce apoptosis and caspase-3-like protease activity. Cancer Res. 1998 Feb 1;58(3):402-8. PMID: 9458080.

Guo Z, Smith TJ, Wang E, et al. Structure-activity relationships of arylalkyl isothiocyanates for the inhibition of 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone metabolism and the modulation of xenobiotic-metabolizing enzymes in rats and mice. Carcinogenesis. 1993 Jun;14(6):1167-73. PMID: 8508504.

" Not dangerous goods.

LKT P2516 S-(N-Phenylbutylthiocarbamoyl)-L-cysteine 25 mg 309.6 Cysteine-ITC conjugate, antioxidant. Phenylbutylisothiocyanate-L-cysteine ≥98% 312.45 C14H20N2O2S2 Ambient -20°C "Son HY, Nishikawa A, Furukawa F, et al. Modifying effects of 4-phenylbutyl isothiocyanate on N-nitrosobis(2-oxopropyl)amine-induced tumorigenesis in hamsters. Cancer Lett. 2000 Nov 28;160(2):141-7. PMID: 11053643.

Yu R, Mandlekar S, Harvey KJ, et al. Chemopreventive isothiocyanates induce apoptosis and caspase-3-like protease activity. Cancer Res. 1998 Feb 1;58(3):402-8. PMID: 9458080.

Guo Z, Smith TJ, Wang E, et al. Structure-activity relationships of arylalkyl isothiocyanates for the inhibition of 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone metabolism and the modulation of xenobiotic-metabolizing enzymes in rats and mice. Carcinogenesis. 1993 Jun;14(6):1167-73. PMID: 8508504.

" Not dangerous goods.

LKT P2516 S-(N-Phenylbutylthiocarbamoyl)-L-cysteine 100 mg 971.1 Cysteine-ITC conjugate, antioxidant. Phenylbutylisothiocyanate-L-cysteine ≥98% 312.45 C14H20N2O2S2 Ambient -20°C "Son HY, Nishikawa A, Furukawa F, et al. Modifying effects of 4-phenylbutyl isothiocyanate on N-nitrosobis(2-oxopropyl)amine-induced tumorigenesis in hamsters. Cancer Lett. 2000 Nov 28;160(2):141-7. PMID: 11053643.

Yu R, Mandlekar S, Harvey KJ, et al. Chemopreventive isothiocyanates induce apoptosis and caspase-3-like protease activity. Cancer Res. 1998 Feb 1;58(3):402-8. PMID: 9458080.

Guo Z, Smith TJ, Wang E, et al. Structure-activity relationships of arylalkyl isothiocyanates for the inhibition of 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone metabolism and the modulation of xenobiotic-metabolizing enzymes in rats and mice. Carcinogenesis. 1993 Jun;14(6):1167-73. PMID: 8508504.

" Not dangerous goods.

LKT P2514 S-(N-Phenylbutylthiocarbamoyl)-glutathione 5 mg 301.5 Glutathione-ITC conjugate, antioxidant. Phenylbutylisothiocyanate-glutathione ≥98% 498.62 C21H30N4O6S2 Ambient -20°C "Son HY, Nishikawa A, Furukawa F, et al. Modifying effects of 4-phenylbutyl isothiocyanate on N-nitrosobis(2-oxopropyl)amine-induced tumorigenesis in hamsters. Cancer Lett. 2000 Nov 28;160(2):141-7. PMID: 11053643.

Yu R, Mandlekar S, Harvey KJ, et al. Chemopreventive isothiocyanates induce apoptosis and caspase-3-like protease activity. Cancer Res. 1998 Feb 1;58(3):402-8. PMID: 9458080.

Guo Z, Smith TJ, Wang E, et al. Structure-activity relationships of arylalkyl isothiocyanates for the inhibition of 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone metabolism and the modulation of xenobiotic-metabolizing enzymes in rats and mice. Carcinogenesis. 1993 Jun;14(6):1167-73. PMID: 8508504.

" Not dangerous goods.

LKT P2514 S-(N-Phenylbutylthiocarbamoyl)-glutathione 10 mg 535.7 Glutathione-ITC conjugate, antioxidant. Phenylbutylisothiocyanate-glutathione ≥98% 498.62 C21H30N4O6S2 Ambient -20°C "Son HY, Nishikawa A, Furukawa F, et al. Modifying effects of 4-phenylbutyl isothiocyanate on N-nitrosobis(2-oxopropyl)amine-induced tumorigenesis in hamsters. Cancer Lett. 2000 Nov 28;160(2):141-7. PMID: 11053643.

Yu R, Mandlekar S, Harvey KJ, et al. Chemopreventive isothiocyanates induce apoptosis and caspase-3-like protease activity. Cancer Res. 1998 Feb 1;58(3):402-8. PMID: 9458080.

Guo Z, Smith TJ, Wang E, et al. Structure-activity relationships of arylalkyl isothiocyanates for the inhibition of 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone metabolism and the modulation of xenobiotic-metabolizing enzymes in rats and mice. Carcinogenesis. 1993 Jun;14(6):1167-73. PMID: 8508504.

" Not dangerous goods.

LKT P2514 S-(N-Phenylbutylthiocarbamoyl)-glutathione 25 mg 1088.3 Glutathione-ITC conjugate, antioxidant. Phenylbutylisothiocyanate-glutathione ≥98% 498.62 C21H30N4O6S2 Ambient -20°C "Son HY, Nishikawa A, Furukawa F, et al. Modifying effects of 4-phenylbutyl isothiocyanate on N-nitrosobis(2-oxopropyl)amine-induced tumorigenesis in hamsters. Cancer Lett. 2000 Nov 28;160(2):141-7. PMID: 11053643.

Yu R, Mandlekar S, Harvey KJ, et al. Chemopreventive isothiocyanates induce apoptosis and caspase-3-like protease activity. Cancer Res. 1998 Feb 1;58(3):402-8. PMID: 9458080.

Guo Z, Smith TJ, Wang E, et al. Structure-activity relationships of arylalkyl isothiocyanates for the inhibition of 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone metabolism and the modulation of xenobiotic-metabolizing enzymes in rats and mice. Carcinogenesis. 1993 Jun;14(6):1167-73. PMID: 8508504.

" Not dangerous goods.

LKT P2512 S-(N-Phenethylthiocarbamoyl)-L-cysteine 10 mg 75.3 Cysteine-ITC conjugate, antioxidant. Phenethylisothiocyanate-L-cysteine ≥98% 284.4 C12H16N2O2S2 Ambient -20°C "Tusskorn O, Senggunprai L, Prawan A, et al Phenethyl isothiocyanate induces calcium mobilization and mitochondrial cell death pathway in cholangiocarcinoma KKU-M214 cells. BMC Cancer. 2013 Dec 5;13(1):571. PMID: 24304591.

Stan SD, Singh SV, Whitcomb DC, et al. Phenethyl Isothiocyanate Inhibits Proliferation and Induces Apoptosis in Pancreatic Cancer Cells In Vitro and in a MIAPaca2 Xenograft Animal Model. Nutr Cancer. 2013 Nov 6. [Epub ahead of print]. PMID: 24195616.

Gupta B, Chiang L, Chae K, et al. Phenethyl isothiocyanate inhibits hypoxia-induced accumulation of HIF-1α and VEGF expression in human glioma cells. Food Chem. 2013 Dec 1;141(3):1841-6. PMID: 23870899.

Thomson SJ, Brown KK, Pullar JM, et al. Phenethyl isothiocyanate triggers apoptosis in Jurkat cells made resistant by the overexpression of Bcl-2. Cancer Res. 2006 Jul 1;66(13):6772-7. PMID: 16818653.

Yu R, Mandlekar S, Harvey KJ, et al. Chemopreventive isothiocyanates induce apoptosis and caspase-3-like protease activity. Cancer Res. 1998 Feb 1;58(3):402-8. PMID: 9458080.

Yu R, Jiao JJ, Duh JL, et al. Phenethyl isothiocyanate, a natural chemopreventive agent, activates c-Jun N-terminal kinase 1. Cancer Res. 1996 Jul 1;56(13):2954-9. PMID: 8674048.

Guo Z, Smith TJ, Wang E, et al. Structure-activity relationships of arylalkyl isothiocyanates for the inhibition of 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone metabolism and the modulation of xenobiotic-metabolizing enzymes in rats and mice. Carcinogenesis. 1993 Jun;14(6):1167-73. PMID: 8508504.

" Not dangerous goods.

LKT P2512 S-(N-Phenethylthiocarbamoyl)-L-cysteine 25 mg 133.9 Cysteine-ITC conjugate, antioxidant. Phenethylisothiocyanate-L-cysteine ≥98% 284.4 C12H16N2O2S2 Ambient -20°C "Tusskorn O, Senggunprai L, Prawan A, et al Phenethyl isothiocyanate induces calcium mobilization and mitochondrial cell death pathway in cholangiocarcinoma KKU-M214 cells. BMC Cancer. 2013 Dec 5;13(1):571. PMID: 24304591.

Stan SD, Singh SV, Whitcomb DC, et al. Phenethyl Isothiocyanate Inhibits Proliferation and Induces Apoptosis in Pancreatic Cancer Cells In Vitro and in a MIAPaca2 Xenograft Animal Model. Nutr Cancer. 2013 Nov 6. [Epub ahead of print]. PMID: 24195616.

Gupta B, Chiang L, Chae K, et al. Phenethyl isothiocyanate inhibits hypoxia-induced accumulation of HIF-1α and VEGF expression in human glioma cells. Food Chem. 2013 Dec 1;141(3):1841-6. PMID: 23870899.

Thomson SJ, Brown KK, Pullar JM, et al. Phenethyl isothiocyanate triggers apoptosis in Jurkat cells made resistant by the overexpression of Bcl-2. Cancer Res. 2006 Jul 1;66(13):6772-7. PMID: 16818653.

Yu R, Mandlekar S, Harvey KJ, et al. Chemopreventive isothiocyanates induce apoptosis and caspase-3-like protease activity. Cancer Res. 1998 Feb 1;58(3):402-8. PMID: 9458080.

Yu R, Jiao JJ, Duh JL, et al. Phenethyl isothiocyanate, a natural chemopreventive agent, activates c-Jun N-terminal kinase 1. Cancer Res. 1996 Jul 1;56(13):2954-9. PMID: 8674048.

Guo Z, Smith TJ, Wang E, et al. Structure-activity relationships of arylalkyl isothiocyanates for the inhibition of 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone metabolism and the modulation of xenobiotic-metabolizing enzymes in rats and mice. Carcinogenesis. 1993 Jun;14(6):1167-73. PMID: 8508504.

" Not dangerous goods.

LKT P2512 S-(N-Phenethylthiocarbamoyl)-L-cysteine 100 mg 410.1 Cysteine-ITC conjugate, antioxidant. Phenethylisothiocyanate-L-cysteine ≥98% 284.4 C12H16N2O2S2 Ambient -20°C "Tusskorn O, Senggunprai L, Prawan A, et al Phenethyl isothiocyanate induces calcium mobilization and mitochondrial cell death pathway in cholangiocarcinoma KKU-M214 cells. BMC Cancer. 2013 Dec 5;13(1):571. PMID: 24304591.

Stan SD, Singh SV, Whitcomb DC, et al. Phenethyl Isothiocyanate Inhibits Proliferation and Induces Apoptosis in Pancreatic Cancer Cells In Vitro and in a MIAPaca2 Xenograft Animal Model. Nutr Cancer. 2013 Nov 6. [Epub ahead of print]. PMID: 24195616.

Gupta B, Chiang L, Chae K, et al. Phenethyl isothiocyanate inhibits hypoxia-induced accumulation of HIF-1α and VEGF expression in human glioma cells. Food Chem. 2013 Dec 1;141(3):1841-6. PMID: 23870899.

Thomson SJ, Brown KK, Pullar JM, et al. Phenethyl isothiocyanate triggers apoptosis in Jurkat cells made resistant by the overexpression of Bcl-2. Cancer Res. 2006 Jul 1;66(13):6772-7. PMID: 16818653.

Yu R, Mandlekar S, Harvey KJ, et al. Chemopreventive isothiocyanates induce apoptosis and caspase-3-like protease activity. Cancer Res. 1998 Feb 1;58(3):402-8. PMID: 9458080.

Yu R, Jiao JJ, Duh JL, et al. Phenethyl isothiocyanate, a natural chemopreventive agent, activates c-Jun N-terminal kinase 1. Cancer Res. 1996 Jul 1;56(13):2954-9. PMID: 8674048.

Guo Z, Smith TJ, Wang E, et al. Structure-activity relationships of arylalkyl isothiocyanates for the inhibition of 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone metabolism and the modulation of xenobiotic-metabolizing enzymes in rats and mice. Carcinogenesis. 1993 Jun;14(6):1167-73. PMID: 8508504.

" Not dangerous goods.

LKT M1975 S-(N-Methylthiocarbamoyl)-L-cysteine 10 mg 67 Cysteine-ITC conjugate, antioxidant; aldehyde dehydrogenase inhibitor. Methylsiothiocyanate-L-cysteine ≥98% 194.28 C5H10N2O2S2 Ambient -20°C Not dangerous goods.

LKT M1975 S-(N-Methylthiocarbamoyl)-L-cysteine 25 mg 125.6 Cysteine-ITC conjugate, antioxidant; aldehyde dehydrogenase inhibitor. Methylsiothiocyanate-L-cysteine ≥98% 194.28 C5H10N2O2S2 Ambient -20°C Not dangerous goods.

LKT M1975 S-(N-Methylthiocarbamoyl)-L-cysteine 100 mg 376.7 Cysteine-ITC conjugate, antioxidant; aldehyde dehydrogenase inhibitor. Methylsiothiocyanate-L-cysteine ≥98% 194.28 C5H10N2O2S2 Ambient -20°C Not dangerous goods.

LKT M1875 S-(N-Methylsulfinylbutylthiocarbamoyl)-glutathione 5 mg 335 Glutathione-sulforaphane conjugate, antioxidant. Sulforaphane glutathione conjugate 289711-21-3 ≥98% 484.61 C16H28N4O7S3 Ambient -20°C Water Keum YS, Khor TO, Lin W, et al. Pharmacokinetics and pharmacodynamics of broccoli sprouts on the suppression of prostate cancer in transgenic adenocarcinoma of mouse prostate (TRAMP) mice: implication of induction of Nrf2, HO-1 and apoptosis and the suppression of Akt-dependent kinase pathway. Pharm Res. 2009 Oct;26(10):2324-31. PMID: 19669099. Not dangerous goods.

LKT M1875 S-(N-Methylsulfinylbutylthiocarbamoyl)-glutathione 10 mg 585.9 Glutathione-sulforaphane conjugate, antioxidant. Sulforaphane glutathione conjugate 289711-21-3 ≥98% 484.61 C16H28N4O7S3 Ambient -20°C Water Keum YS, Khor TO, Lin W, et al. Pharmacokinetics and pharmacodynamics of broccoli sprouts on the suppression of prostate cancer in transgenic adenocarcinoma of mouse prostate (TRAMP) mice: implication of induction of Nrf2, HO-1 and apoptosis and the suppression of Akt-dependent kinase pathway. Pharm Res. 2009 Oct;26(10):2324-31. PMID: 19669099. Not dangerous goods.

LKT M1875 S-(N-Methylsulfinylbutylthiocarbamoyl)-glutathione 25 mg 1255.7 Glutathione-sulforaphane conjugate, antioxidant. Sulforaphane glutathione conjugate 289711-21-3 ≥98% 484.61 C16H28N4O7S3 Ambient -20°C Water Keum YS, Khor TO, Lin W, et al. Pharmacokinetics and pharmacodynamics of broccoli sprouts on the suppression of prostate cancer in transgenic adenocarcinoma of mouse prostate (TRAMP) mice: implication of induction of Nrf2, HO-1 and apoptosis and the suppression of Akt-dependent kinase pathway. Pharm Res. 2009 Oct;26(10):2324-31. PMID: 19669099. Not dangerous goods.

LKT A0910 N-Acetyl-S-(N′-phenylthiocarbamoyl)-L-cysteine 10 mg 67 Cysteine-ITC conjugate, antioxidant. ≥98% 298.38 C12H14N2O3S2 Ambient -20°C "Martelli A, Testai L, Citi V, et al. Pharmacological characterization of the vascular effects of aryl isothiocyanates: Is hydrogen sulfide the real player? Vascul Pharmacol. 2013 Nov 25. pii: S1537-1891(13)00138-9. PMID: 24287004.

Abreu AC, Borges A, Simões LC, et al. Antibacterial activity of phenyl isothiocyanate on Escherichia coli and Staphylococcus aureus. Med Chem. 2013 Aug;9(5):756-61. PMID: 22974327.

Schroeder NE, Macguidwin AE. Mortality and behavior in Heterodera glycines juveniles following exposure to isothiocyanate compounds. J Nematol. 2010 Sep;42(3):194-200. PMID: 22736856.

Beevi SS, Mangamoori LN, Dhand V, et al. Isothiocyanate profile and selective antibacterial activity of root, stem, and leaf extracts derived from Raphanus sativus L. Foodborne Pathog Dis. 2009 Jan-Feb;6(1):129-36. PMID: 19182965.

Thejass P, Kuttan G. Inhibition of endothelial cell differentiation and proinflammatory cytokine production during angiogenesis by allyl isothiocyanate and phenyl isothiocyanate. Integr Cancer Ther. 2007 Dec;6(4):389-99. PMID: 18048887.

Thejass P, Kuttan G. Allyl isothiocyanate (AITC) and phenyl isothiocyanate (PITC) inhibit tumour-specific angiogenesis by downregulating nitric oxide (NO) and tumour necrosis factor-alpha (TNF-alpha) production. Nitric Oxide. 2007 Mar;16(2):247-57. PMID: 17097904.

Manesh C, Kuttan G. Effect of naturally occurring isothiocyanates on the immune system. Immunopharmacol Immunotoxicol. 2003 Aug;25(3):451-9. PMID: 19180807.

Manesh C, Kuttan G. Anti-tumour and anti-oxidant activity of naturally occurring isothiocyanates. J Exp Clin Cancer Res. 2003 Jun;22(2):193-9. PMID: 12866569.

" Not dangerous goods.

LKT A0910 N-Acetyl-S-(N′-phenylthiocarbamoyl)-L-cysteine 25 mg 133.9 Cysteine-ITC conjugate, antioxidant. ≥98% 298.38 C12H14N2O3S2 Ambient -20°C "Martelli A, Testai L, Citi V, et al. Pharmacological characterization of the vascular effects of aryl isothiocyanates: Is hydrogen sulfide the real player? Vascul Pharmacol. 2013 Nov 25. pii: S1537-1891(13)00138-9. PMID: 24287004.

Abreu AC, Borges A, Simões LC, et al. Antibacterial activity of phenyl isothiocyanate on Escherichia coli and Staphylococcus aureus. Med Chem. 2013 Aug;9(5):756-61. PMID: 22974327.

Schroeder NE, Macguidwin AE. Mortality and behavior in Heterodera glycines juveniles following exposure to isothiocyanate compounds. J Nematol. 2010 Sep;42(3):194-200. PMID: 22736856.

Beevi SS, Mangamoori LN, Dhand V, et al. Isothiocyanate profile and selective antibacterial activity of root, stem, and leaf extracts derived from Raphanus sativus L. Foodborne Pathog Dis. 2009 Jan-Feb;6(1):129-36. PMID: 19182965.

Thejass P, Kuttan G. Inhibition of endothelial cell differentiation and proinflammatory cytokine production during angiogenesis by allyl isothiocyanate and phenyl isothiocyanate. Integr Cancer Ther. 2007 Dec;6(4):389-99. PMID: 18048887.

Thejass P, Kuttan G. Allyl isothiocyanate (AITC) and phenyl isothiocyanate (PITC) inhibit tumour-specific angiogenesis by downregulating nitric oxide (NO) and tumour necrosis factor-alpha (TNF-alpha) production. Nitric Oxide. 2007 Mar;16(2):247-57. PMID: 17097904.

Manesh C, Kuttan G. Effect of naturally occurring isothiocyanates on the immune system. Immunopharmacol Immunotoxicol. 2003 Aug;25(3):451-9. PMID: 19180807.

Manesh C, Kuttan G. Anti-tumour and anti-oxidant activity of naturally occurring isothiocyanates. J Exp Clin Cancer Res. 2003 Jun;22(2):193-9. PMID: 12866569.

" Not dangerous goods.

LKT A0910 N-Acetyl-S-(N′-phenylthiocarbamoyl)-L-cysteine 100 mg 393.3 Cysteine-ITC conjugate, antioxidant. ≥98% 298.38 C12H14N2O3S2 Ambient -20°C "Martelli A, Testai L, Citi V, et al. Pharmacological characterization of the vascular effects of aryl isothiocyanates: Is hydrogen sulfide the real player? Vascul Pharmacol. 2013 Nov 25. pii: S1537-1891(13)00138-9. PMID: 24287004.

Abreu AC, Borges A, Simões LC, et al. Antibacterial activity of phenyl isothiocyanate on Escherichia coli and Staphylococcus aureus. Med Chem. 2013 Aug;9(5):756-61. PMID: 22974327.

Schroeder NE, Macguidwin AE. Mortality and behavior in Heterodera glycines juveniles following exposure to isothiocyanate compounds. J Nematol. 2010 Sep;42(3):194-200. PMID: 22736856.

Beevi SS, Mangamoori LN, Dhand V, et al. Isothiocyanate profile and selective antibacterial activity of root, stem, and leaf extracts derived from Raphanus sativus L. Foodborne Pathog Dis. 2009 Jan-Feb;6(1):129-36. PMID: 19182965.

Thejass P, Kuttan G. Inhibition of endothelial cell differentiation and proinflammatory cytokine production during angiogenesis by allyl isothiocyanate and phenyl isothiocyanate. Integr Cancer Ther. 2007 Dec;6(4):389-99. PMID: 18048887.

Thejass P, Kuttan G. Allyl isothiocyanate (AITC) and phenyl isothiocyanate (PITC) inhibit tumour-specific angiogenesis by downregulating nitric oxide (NO) and tumour necrosis factor-alpha (TNF-alpha) production. Nitric Oxide. 2007 Mar;16(2):247-57. PMID: 17097904.

Manesh C, Kuttan G. Effect of naturally occurring isothiocyanates on the immune system. Immunopharmacol Immunotoxicol. 2003 Aug;25(3):451-9. PMID: 19180807.

Manesh C, Kuttan G. Anti-tumour and anti-oxidant activity of naturally occurring isothiocyanates. J Exp Clin Cancer Res. 2003 Jun;22(2):193-9. PMID: 12866569.

" Not dangerous goods.

LKT A0902 N-Acetyl-S-(N′-phenylhexylthiocarbamoyl)-L-cysteine 10 mg 142.4 Cysteine-ITC conjugate, antioxidant; HDAC inhibitor. Acetyl phenylhexylisothiocyanate -L-cysteine ≥98% 382.54 C18H26N2O3S2 Ambient -20°C "Lu Q, Lin X, Feng J, et al. Phenylhexyl isothiocyanate has dual function as histone deacetylase inhibitor and hypomethylating agent and can inhibit myeloma cell growth by targeting critical pathways. J Hematol Oncol. 2008 Jun 9;1:6. PMID: 18577263.

Lu L, Liu D, Ma X, et al. The phenylhexyl isothiocyanate induces apoptosis and inhibits leukemia cell growth in vivo. Oncol Rep. 2006 Dec;16(6):1363-7. PMID: 17089062.

Morse MA, Eklind KI, Hecht SS, et al. Structure-activity relationships for inhibition of 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone lung tumorigenesis by arylalkyl isothiocyanates in A/J mice. Cancer Res. 1991 Apr 1;51(7):1846-50. PMID: 2004368.

" Not dangerous goods.

LKT A0902 N-Acetyl-S-(N′-phenylhexylthiocarbamoyl)-L-cysteine 25 mg 309.6 Cysteine-ITC conjugate, antioxidant; HDAC inhibitor. Acetyl phenylhexylisothiocyanate -L-cysteine ≥98% 382.54 C18H26N2O3S2 Ambient -20°C "Lu Q, Lin X, Feng J, et al. Phenylhexyl isothiocyanate has dual function as histone deacetylase inhibitor and hypomethylating agent and can inhibit myeloma cell growth by targeting critical pathways. J Hematol Oncol. 2008 Jun 9;1:6. PMID: 18577263.

Lu L, Liu D, Ma X, et al. The phenylhexyl isothiocyanate induces apoptosis and inhibits leukemia cell growth in vivo. Oncol Rep. 2006 Dec;16(6):1363-7. PMID: 17089062.

Morse MA, Eklind KI, Hecht SS, et al. Structure-activity relationships for inhibition of 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone lung tumorigenesis by arylalkyl isothiocyanates in A/J mice. Cancer Res. 1991 Apr 1;51(7):1846-50. PMID: 2004368.

" Not dangerous goods.

LKT A0902 N-Acetyl-S-(N′-phenylhexylthiocarbamoyl)-L-cysteine 100 mg 971.1 Cysteine-ITC conjugate, antioxidant; HDAC inhibitor. Acetyl phenylhexylisothiocyanate -L-cysteine ≥98% 382.54 C18H26N2O3S2 Ambient -20°C "Lu Q, Lin X, Feng J, et al. Phenylhexyl isothiocyanate has dual function as histone deacetylase inhibitor and hypomethylating agent and can inhibit myeloma cell growth by targeting critical pathways. J Hematol Oncol. 2008 Jun 9;1:6. PMID: 18577263.

Lu L, Liu D, Ma X, et al. The phenylhexyl isothiocyanate induces apoptosis and inhibits leukemia cell growth in vivo. Oncol Rep. 2006 Dec;16(6):1363-7. PMID: 17089062.

Morse MA, Eklind KI, Hecht SS, et al. Structure-activity relationships for inhibition of 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone lung tumorigenesis by arylalkyl isothiocyanates in A/J mice. Cancer Res. 1991 Apr 1;51(7):1846-50. PMID: 2004368.

" Not dangerous goods.

LKT A0823 N-Acetyl-S-(N′-methylthiocarbamoyl)-L-cysteine 10 mg 75.3 Cysteine-ITC conjugate, antioxidant; aldehyde dehydrogenase inhibitor. Acetyl methylisothiocyanate-L-cysteine ≥98% 236.31 C7H12N2O3S2 Ambient -20°C "Ren Y, Lee B, Mahon D, et al. Fumigation of wheat using liquid ethyl formate plus methyl isothiocyanate in 50-tonne farm bins. J Econ Entomol. 2008 Apr;101(2):623-30. PMID: 18459432.

Kassie F, Laky B, Nobis E, et al. Genotoxic effects of methyl isothiocyanate. Mutat Res. 2001 Jan 25;490(1):1-9. Erratum in: Mutat Res 2001 May 31;492(1-2):111-3.  PMID: 11152966.

Staub RE, Sparks SE, Quistad GB, et al. S-methylation as a bioactivation mechanism for mono- and dithiocarbamate pesticides as aldehyde dehydrogenase inhibitors. Chem Res Toxicol. 1995 Dec;8(8):1063-9. PMID: 8605289.

Greco N, Elia F, Brandonisio A. Control of Heterodera carotae, Ditylenchus dipsaci, and Meloidogyne javanica with Fumigant and Nonfumigant Nematicides. J Nematol. 1986 Jul;18(3):359-63. PMID: 19294191.

" Not dangerous goods.

LKT A0823 N-Acetyl-S-(N′-methylthiocarbamoyl)-L-cysteine 25 mg 133.9 Cysteine-ITC conjugate, antioxidant; aldehyde dehydrogenase inhibitor. Acetyl methylisothiocyanate-L-cysteine ≥98% 236.31 C7H12N2O3S2 Ambient -20°C "Ren Y, Lee B, Mahon D, et al. Fumigation of wheat using liquid ethyl formate plus methyl isothiocyanate in 50-tonne farm bins. J Econ Entomol. 2008 Apr;101(2):623-30. PMID: 18459432.

Kassie F, Laky B, Nobis E, et al. Genotoxic effects of methyl isothiocyanate. Mutat Res. 2001 Jan 25;490(1):1-9. Erratum in: Mutat Res 2001 May 31;492(1-2):111-3.  PMID: 11152966.

Staub RE, Sparks SE, Quistad GB, et al. S-methylation as a bioactivation mechanism for mono- and dithiocarbamate pesticides as aldehyde dehydrogenase inhibitors. Chem Res Toxicol. 1995 Dec;8(8):1063-9. PMID: 8605289.

Greco N, Elia F, Brandonisio A. Control of Heterodera carotae, Ditylenchus dipsaci, and Meloidogyne javanica with Fumigant and Nonfumigant Nematicides. J Nematol. 1986 Jul;18(3):359-63. PMID: 19294191.

" Not dangerous goods.

LKT A0823 N-Acetyl-S-(N′-methylthiocarbamoyl)-L-cysteine 100 mg 410.1 Cysteine-ITC conjugate, antioxidant; aldehyde dehydrogenase inhibitor. Acetyl methylisothiocyanate-L-cysteine ≥98% 236.31 C7H12N2O3S2 Ambient -20°C "Ren Y, Lee B, Mahon D, et al. Fumigation of wheat using liquid ethyl formate plus methyl isothiocyanate in 50-tonne farm bins. J Econ Entomol. 2008 Apr;101(2):623-30. PMID: 18459432.

Kassie F, Laky B, Nobis E, et al. Genotoxic effects of methyl isothiocyanate. Mutat Res. 2001 Jan 25;490(1):1-9. Erratum in: Mutat Res 2001 May 31;492(1-2):111-3.  PMID: 11152966.

Staub RE, Sparks SE, Quistad GB, et al. S-methylation as a bioactivation mechanism for mono- and dithiocarbamate pesticides as aldehyde dehydrogenase inhibitors. Chem Res Toxicol. 1995 Dec;8(8):1063-9. PMID: 8605289.

Greco N, Elia F, Brandonisio A. Control of Heterodera carotae, Ditylenchus dipsaci, and Meloidogyne javanica with Fumigant and Nonfumigant Nematicides. J Nematol. 1986 Jul;18(3):359-63. PMID: 19294191.

" Not dangerous goods.

LKT A0820 N-Acetyl-S-(N′-benzylthiocarbamoyl)-L-cysteine 10 mg 63.7 Cysteine-ITC conjugate, BITC derivative, antioxidant. Acetyl-benzylisothiocyanate-L-cysteine ≥98% 312.41 C13H16N2O3S2 Ambient -20°C "Dufour V, Stahl M, Rosenfeld E, et al. Insights into the mode of action of benzyl isothiocyanate on Campylobacter jejuni. Appl Environ Microbiol. 2013 Nov;79(22):6958-68. PMID: 24014524.

Ni WY, Hsiao YP, Hsu SC, et al. Oral administration of benzyl-isothiocyanate inhibits in vivo growth of subcutaneous xenograft tumors of human malignant melanoma A375.S2 cells. In Vivo. 2013 Sep-Oct;27(5):623-6. PMID: 23988897.

Zhu Y, Zhuang JX, Wang Q, et al. Inhibitory effect of benzyl isothiocyanate on proliferation in vitro of human glioma cells. Asian Pac J Cancer Prev. 2013;14(4):2607-10. PMID: 23725183.

Kim SH, Sehrawat A, Singh SV. Dietary chemopreventative benzyl isothiocyanate inhibits breast cancer stem cells in vitro and in vivo. Cancer Prev Res (Phila). 2013 Aug;6(8):782-90. PMID: 23661606.

Lin JF, Tsai TF, Liao PC, et al. Benzyl isothiocyanate induces protective autophagy in human prostate cancer cells via inhibition of mTOR signaling. Carcinogenesis. 2013 Feb;34(2):406-14. PMID: 23172666.

Boreddy SR, Sahu RP, Srivastava SK. Benzyl isothiocyanate suppresses pancreatic tumor angiogenesis and invasion by inhibiting HIF-α/VEGF/Rho-GTPases: pivotal role of STAT-3. PLoS One. 2011;6(10):e25799. PMID: 22016776.

Schroeder NE, Macguidwin AE. Mortality and behavior in Heterodera glycines juveniles following exposure to isothiocyanate compounds. J Nematol. 2010 Sep;42(3):194-200. PMID: 22736856.

Beevi SS, Mangamoori LN, Dhand V, et al. Isothiocyanate profile and selective antibacterial activity of root, stem, and leaf extracts derived from Raphanus sativus L. Foodborne Pathog Dis. 2009 Jan-Feb;6(1):129-36. PMID: 19182965.

" Not dangerous goods.

LKT A0820 N-Acetyl-S-(N′-benzylthiocarbamoyl)-L-cysteine 25 mg 125.6 Cysteine-ITC conjugate, BITC derivative, antioxidant. Acetyl-benzylisothiocyanate-L-cysteine ≥98% 312.41 C13H16N2O3S2 Ambient -20°C "Dufour V, Stahl M, Rosenfeld E, et al. Insights into the mode of action of benzyl isothiocyanate on Campylobacter jejuni. Appl Environ Microbiol. 2013 Nov;79(22):6958-68. PMID: 24014524.

Ni WY, Hsiao YP, Hsu SC, et al. Oral administration of benzyl-isothiocyanate inhibits in vivo growth of subcutaneous xenograft tumors of human malignant melanoma A375.S2 cells. In Vivo. 2013 Sep-Oct;27(5):623-6. PMID: 23988897.

Zhu Y, Zhuang JX, Wang Q, et al. Inhibitory effect of benzyl isothiocyanate on proliferation in vitro of human glioma cells. Asian Pac J Cancer Prev. 2013;14(4):2607-10. PMID: 23725183.

Kim SH, Sehrawat A, Singh SV. Dietary chemopreventative benzyl isothiocyanate inhibits breast cancer stem cells in vitro and in vivo. Cancer Prev Res (Phila). 2013 Aug;6(8):782-90. PMID: 23661606.

Lin JF, Tsai TF, Liao PC, et al. Benzyl isothiocyanate induces protective autophagy in human prostate cancer cells via inhibition of mTOR signaling. Carcinogenesis. 2013 Feb;34(2):406-14. PMID: 23172666.

Boreddy SR, Sahu RP, Srivastava SK. Benzyl isothiocyanate suppresses pancreatic tumor angiogenesis and invasion by inhibiting HIF-α/VEGF/Rho-GTPases: pivotal role of STAT-3. PLoS One. 2011;6(10):e25799. PMID: 22016776.

Schroeder NE, Macguidwin AE. Mortality and behavior in Heterodera glycines juveniles following exposure to isothiocyanate compounds. J Nematol. 2010 Sep;42(3):194-200. PMID: 22736856.

Beevi SS, Mangamoori LN, Dhand V, et al. Isothiocyanate profile and selective antibacterial activity of root, stem, and leaf extracts derived from Raphanus sativus L. Foodborne Pathog Dis. 2009 Jan-Feb;6(1):129-36. PMID: 19182965.

" Not dangerous goods.

LKT A0820 N-Acetyl-S-(N′-benzylthiocarbamoyl)-L-cysteine 100 mg 376.7 Cysteine-ITC conjugate, BITC derivative, antioxidant. Acetyl-benzylisothiocyanate-L-cysteine ≥98% 312.41 C13H16N2O3S2 Ambient -20°C "Dufour V, Stahl M, Rosenfeld E, et al. Insights into the mode of action of benzyl isothiocyanate on Campylobacter jejuni. Appl Environ Microbiol. 2013 Nov;79(22):6958-68. PMID: 24014524.

Ni WY, Hsiao YP, Hsu SC, et al. Oral administration of benzyl-isothiocyanate inhibits in vivo growth of subcutaneous xenograft tumors of human malignant melanoma A375.S2 cells. In Vivo. 2013 Sep-Oct;27(5):623-6. PMID: 23988897.

Zhu Y, Zhuang JX, Wang Q, et al. Inhibitory effect of benzyl isothiocyanate on proliferation in vitro of human glioma cells. Asian Pac J Cancer Prev. 2013;14(4):2607-10. PMID: 23725183.

Kim SH, Sehrawat A, Singh SV. Dietary chemopreventative benzyl isothiocyanate inhibits breast cancer stem cells in vitro and in vivo. Cancer Prev Res (Phila). 2013 Aug;6(8):782-90. PMID: 23661606.

Lin JF, Tsai TF, Liao PC, et al. Benzyl isothiocyanate induces protective autophagy in human prostate cancer cells via inhibition of mTOR signaling. Carcinogenesis. 2013 Feb;34(2):406-14. PMID: 23172666.

Boreddy SR, Sahu RP, Srivastava SK. Benzyl isothiocyanate suppresses pancreatic tumor angiogenesis and invasion by inhibiting HIF-α/VEGF/Rho-GTPases: pivotal role of STAT-3. PLoS One. 2011;6(10):e25799. PMID: 22016776.

Schroeder NE, Macguidwin AE. Mortality and behavior in Heterodera glycines juveniles following exposure to isothiocyanate compounds. J Nematol. 2010 Sep;42(3):194-200. PMID: 22736856.

Beevi SS, Mangamoori LN, Dhand V, et al. Isothiocyanate profile and selective antibacterial activity of root, stem, and leaf extracts derived from Raphanus sativus L. Foodborne Pathog Dis. 2009 Jan-Feb;6(1):129-36. PMID: 19182965.

" Not dangerous goods.

LKT A5476 Antagonist G 0.5 mg 180 Peptide, used for drug delivery targeting. 115150-59-9 ≥95% 951.2 C49H66O6N12S CC(C)CC(C(=O)NC(CCSC)C(=O)N)NC(=O)C(CC1=CNC2=CC=CC=C21)NC(=O)C(CC3=CC=CC=C3)N(C)C(=O)C(CC4=CNC5=CC=CC=C54)NC(=O)C(CCCN=C(N)N)N Ambient -20°C Moreira JN, Gaspar R. Antagonist G-mediated targeting and cytotoxicity of liposomal doxorubicin in NCI-H82 variant small cell lung cancer. Braz J Med Biol Res. 2004 Aug;37(8):1185-92. PMID: 15273819. Not dangerous goods.

LKT A5476 Antagonist G 1 mg 306.1 Peptide, used for drug delivery targeting. 115150-59-9 ≥95% 951.2 C49H66O6N12S CC(C)CC(C(=O)NC(CCSC)C(=O)N)NC(=O)C(CC1=CNC2=CC=CC=C21)NC(=O)C(CC3=CC=CC=C3)N(C)C(=O)C(CC4=CNC5=CC=CC=C54)NC(=O)C(CCCN=C(N)N)N Ambient -20°C Moreira JN, Gaspar R. Antagonist G-mediated targeting and cytotoxicity of liposomal doxorubicin in NCI-H82 variant small cell lung cancer. Braz J Med Biol Res. 2004 Aug;37(8):1185-92. PMID: 15273819. Not dangerous goods.

LKT A5476 Antagonist G 2.5 mg 540 Peptide, used for drug delivery targeting. 115150-59-9 ≥95% 951.2 C49H66O6N12S CC(C)CC(C(=O)NC(CCSC)C(=O)N)NC(=O)C(CC1=CNC2=CC=CC=C21)NC(=O)C(CC3=CC=CC=C3)N(C)C(=O)C(CC4=CNC5=CC=CC=C54)NC(=O)C(CCCN=C(N)N)N Ambient -20°C Moreira JN, Gaspar R. Antagonist G-mediated targeting and cytotoxicity of liposomal doxorubicin in NCI-H82 variant small cell lung cancer. Braz J Med Biol Res. 2004 Aug;37(8):1185-92. PMID: 15273819. Not dangerous goods.

LKT G5875 Gossypol Acetic Acid 250 mg 126.7 Bcl-2, Bcl-xl, sialyl transferase inhibitor. 1,1',6,6',7,7'-Hexahydroxy-3,3'-dimethyl-5,5'-bis(1- methylethyl)[2,2'-binaphthalene]-8,8'-dicarboxaldehyde-acetic acid 2,2'-bis(8-Formyl-1,6,7-trihydroxy-5-isopropyl-3-methylnaphthalene)-acetic acid 12542-36-8 ≥98% 578.61 C30H30O8 C2H4O2 CC1=C(C(=C2C(=C1)C(=C(C(=C2C=O)O)O)C(C)C)O)C3=C(C=C4C(=C3O)C(=C(C(=C4C(C)C)O)O)C=O)C.CC(=O)O Ambient 4°C Soluble in DMSO, methanol  or ethanol. Insoluble in water. "Deng S, Yuan H, Yi J, et al. Gossypol acetic acid induces apoptosis in RAW264.7 cells via a caspase-dependent mitochondrial signaling pathway. J Vet Sci. 2013;14(3):281-9. PMID: 23820203.

Hall C, Troutman SM, Price DK, et al. Bcl-2 family of proteins as therapeutic targets in genitourinary neoplasms. Clin Genitourin Cancer. 2013 Mar;11(1):10-9. PMID: 23083798.

Kisim A, Atmaca H, Cakar B, et al. Pretreatment with AT-101 enhances tumor necrosis factor-related apoptosis-inducing ligand (TRAIL)-induced apoptosis of breast cancer cells by inducing death receptors 4 and 5 protein levels. J Cancer Res Clin Oncol. 2012 Jul;138(7):1155-63. PMID: 22411600.

El-Sharaky AS, Wahby MM, Bader El-Dein MM, et al. Mutual anti-oxidative effect of gossypol acetic acid and gossypol-iron complex on hepatic lipid peroxidation in male rats. Food Chem Toxicol. 2009 Nov;47(11):2735-41. PMID: 19665044.

Loberg RD, McGregor N, Ying C, et al. In vivo evaluation of AT-101 (R-(-)-gossypol acetic acid) in androgen-independent growth of VCaP prostate cancer cells in combination with surgical castration. Neoplasia. 2007 Dec;9(12):1030-7. PMID: 18084610.

Yildirim-Aksoy M, Lim C, Dowd MK, et al. In vitro inhibitory effect of gossypol from gossypol-acetic acid, and (+)- and (-)-isomers of gossypol on the growth of Edwardsiella ictaluri. J Appl Microbiol. 2004;97(1):87-92. PMID: 15186445.

Sharma S, Kumar M, Goyal RB, et al. Reversible antispermatogenic effect of gossypol in langur monkeys (Presbytis entellus entellus). Adv Contracept. 1999;15(1):15-27. PMID: 10794043.

Teng CS. Reversible changes in the content of cellular and microtubular tubulin in spermatogenic cells after gossypol treatment. Contraception. 1997 Jan;55(1):41-6. PMID: 9013060.

Levinsky H, Singer R, Sagiv M, et al. Inhibition of sialyl transferase activity by gossypol acetic acid in human seminal plasma. Andrologia. 1991 Mar-Apr;23(2):159-61. PMID: 1952122.

" Carc. Cat 3 Not dangerous goods.

LKT G5875 Gossypol Acetic Acid 1 g 402.3 Bcl-2, Bcl-xl, sialyl transferase inhibitor. 1,1',6,6',7,7'-Hexahydroxy-3,3'-dimethyl-5,5'-bis(1- methylethyl)[2,2'-binaphthalene]-8,8'-dicarboxaldehyde-acetic acid 2,2'-bis(8-Formyl-1,6,7-trihydroxy-5-isopropyl-3-methylnaphthalene)-acetic acid 12542-36-8 ≥98% 578.61 C30H30O8 C2H4O2 CC1=C(C(=C2C(=C1)C(=C(C(=C2C=O)O)O)C(C)C)O)C3=C(C=C4C(=C3O)C(=C(C(=C4C(C)C)O)O)C=O)C.CC(=O)O Ambient 4°C Soluble in DMSO, methanol  or ethanol. Insoluble in water. "Deng S, Yuan H, Yi J, et al. Gossypol acetic acid induces apoptosis in RAW264.7 cells via a caspase-dependent mitochondrial signaling pathway. J Vet Sci. 2013;14(3):281-9. PMID: 23820203.

Hall C, Troutman SM, Price DK, et al. Bcl-2 family of proteins as therapeutic targets in genitourinary neoplasms. Clin Genitourin Cancer. 2013 Mar;11(1):10-9. PMID: 23083798.

Kisim A, Atmaca H, Cakar B, et al. Pretreatment with AT-101 enhances tumor necrosis factor-related apoptosis-inducing ligand (TRAIL)-induced apoptosis of breast cancer cells by inducing death receptors 4 and 5 protein levels. J Cancer Res Clin Oncol. 2012 Jul;138(7):1155-63. PMID: 22411600.

El-Sharaky AS, Wahby MM, Bader El-Dein MM, et al. Mutual anti-oxidative effect of gossypol acetic acid and gossypol-iron complex on hepatic lipid peroxidation in male rats. Food Chem Toxicol. 2009 Nov;47(11):2735-41. PMID: 19665044.

Loberg RD, McGregor N, Ying C, et al. In vivo evaluation of AT-101 (R-(-)-gossypol acetic acid) in androgen-independent growth of VCaP prostate cancer cells in combination with surgical castration. Neoplasia. 2007 Dec;9(12):1030-7. PMID: 18084610.

Yildirim-Aksoy M, Lim C, Dowd MK, et al. In vitro inhibitory effect of gossypol from gossypol-acetic acid, and (+)- and (-)-isomers of gossypol on the growth of Edwardsiella ictaluri. J Appl Microbiol. 2004;97(1):87-92. PMID: 15186445.

Sharma S, Kumar M, Goyal RB, et al. Reversible antispermatogenic effect of gossypol in langur monkeys (Presbytis entellus entellus). Adv Contracept. 1999;15(1):15-27. PMID: 10794043.

Teng CS. Reversible changes in the content of cellular and microtubular tubulin in spermatogenic cells after gossypol treatment. Contraception. 1997 Jan;55(1):41-6. PMID: 9013060.

Levinsky H, Singer R, Sagiv M, et al. Inhibition of sialyl transferase activity by gossypol acetic acid in human seminal plasma. Andrologia. 1991 Mar-Apr;23(2):159-61. PMID: 1952122.

" Carc. Cat 3 Not dangerous goods.

LKT C3449 Clodronate Disodium Tetrahydrate 10 mg 62.7 Non-nitrogen bisphosphonate; mitochondrial ATP/ADP translocase inhibitor. Clodronate disodium salt; Dichloromethylene- bisphophonate disodium tetrahydrate Clodronic acid disodium salt, chlodronate sodium, clasteron 88416-50-6 ≥98% 360.92 CH2Cl2Na2O6P2 4H2O C(P(=O)(O)[O-])(P(=O)(O)[O-])(Cl)Cl.[Na+].[Na+] Ambient Ambient Soluble in water to 100 mM "Katzav A, Bina H, Aronovich R, et al. Treatment for experimental autoimmune neuritis with clodronate (Bonefos). Immunol Res. 2013 Jul;56(2-3):334-40. PMID: 23579773.

Soltau J, Zirrgiebel U, Esser N, et al. Antitumoral and antiangiogenic efficacy of bisphosphonates in vitro and in a murine RENCA model. Anticancer Res. 2008 Mar-Apr;28(2A):933-41. PMID: 18507039.

Kellinsalmi M, Mönkkönen H, Mönkkönen J, et al. In vitro comparison of clodronate, pamidronate and zoledronic acid effects on rat osteoclasts and human stem cell-derived osteoblasts. Basic Clin Pharmacol Toxicol. 2005 Dec;97(6):382-91. PMID: 16364054.

Reszka AA, Rodan GA. Mechanism of action of bisphosphonates. Curr Osteoporos Rep. 2003 Sep;1(2):45-52. PMID: 16036064.

Rogers MJ. New insights into the molecular mechanisms of action of bisphosphonates. Curr Pharm Des. 2003;9(32):2643-58. PMID: 14529538.

Lehenkari PP, Kellinsalmi M, Näpänkangas JP, et al. Further insight into mechanism of action of clodronate: inhibition of mitochondrial ADP/ATP translocase by a nonhydrolyzable, adenine-containing metabolite. Mol Pharmacol. 2002 May;61(5):1255-62. PMID: 11961144.

Sato A, Nakashima H, Nakashima M, et al. Involvement of the TNF and FasL produced by CD11b Kupffer cells/macrophages in CCl4-induced acute hepatic injury. PLoS One. 2014 Mar 25;9(3):e92515. PMID: 24667392.

Kimura K, Nakamura Y, Inaba Y, et al. Histidine augments the suppression of hepatic glucose production by central insulin action. Diabetes. 2013 Jul;62(7):2266-2277. PMID: 23474485.

" T Not dangerous goods.

LKT C3449 Clodronate Disodium Tetrahydrate 50 mg 254.9 Non-nitrogen bisphosphonate; mitochondrial ATP/ADP translocase inhibitor. Clodronate disodium salt; Dichloromethylene- bisphophonate disodium tetrahydrate Clodronic acid disodium salt, chlodronate sodium, clasteron 88416-50-6 ≥98% 360.92 CH2Cl2Na2O6P2 4H2O C(P(=O)(O)[O-])(P(=O)(O)[O-])(Cl)Cl.[Na+].[Na+] Ambient Ambient Soluble in water to 100 mM "Katzav A, Bina H, Aronovich R, et al. Treatment for experimental autoimmune neuritis with clodronate (Bonefos). Immunol Res. 2013 Jul;56(2-3):334-40. PMID: 23579773.

Soltau J, Zirrgiebel U, Esser N, et al. Antitumoral and antiangiogenic efficacy of bisphosphonates in vitro and in a murine RENCA model. Anticancer Res. 2008 Mar-Apr;28(2A):933-41. PMID: 18507039.

Kellinsalmi M, Mönkkönen H, Mönkkönen J, et al. In vitro comparison of clodronate, pamidronate and zoledronic acid effects on rat osteoclasts and human stem cell-derived osteoblasts. Basic Clin Pharmacol Toxicol. 2005 Dec;97(6):382-91. PMID: 16364054.

Reszka AA, Rodan GA. Mechanism of action of bisphosphonates. Curr Osteoporos Rep. 2003 Sep;1(2):45-52. PMID: 16036064.

Rogers MJ. New insights into the molecular mechanisms of action of bisphosphonates. Curr Pharm Des. 2003;9(32):2643-58. PMID: 14529538.

Lehenkari PP, Kellinsalmi M, Näpänkangas JP, et al. Further insight into mechanism of action of clodronate: inhibition of mitochondrial ADP/ATP translocase by a nonhydrolyzable, adenine-containing metabolite. Mol Pharmacol. 2002 May;61(5):1255-62. PMID: 11961144.

Sato A, Nakashima H, Nakashima M, et al. Involvement of the TNF and FasL produced by CD11b Kupffer cells/macrophages in CCl4-induced acute hepatic injury. PLoS One. 2014 Mar 25;9(3):e92515. PMID: 24667392.

Kimura K, Nakamura Y, Inaba Y, et al. Histidine augments the suppression of hepatic glucose production by central insulin action. Diabetes. 2013 Jul;62(7):2266-2277. PMID: 23474485.

" T Not dangerous goods.

LKT C3449 Clodronate Disodium Tetrahydrate 100 mg 461 Non-nitrogen bisphosphonate; mitochondrial ATP/ADP translocase inhibitor. Clodronate disodium salt; Dichloromethylene- bisphophonate disodium tetrahydrate Clodronic acid disodium salt, chlodronate sodium, clasteron 88416-50-6 ≥98% 360.92 CH2Cl2Na2O6P2 4H2O C(P(=O)(O)[O-])(P(=O)(O)[O-])(Cl)Cl.[Na+].[Na+] Ambient Ambient Soluble in water to 100 mM "Katzav A, Bina H, Aronovich R, et al. Treatment for experimental autoimmune neuritis with clodronate (Bonefos). Immunol Res. 2013 Jul;56(2-3):334-40. PMID: 23579773.

Soltau J, Zirrgiebel U, Esser N, et al. Antitumoral and antiangiogenic efficacy of bisphosphonates in vitro and in a murine RENCA model. Anticancer Res. 2008 Mar-Apr;28(2A):933-41. PMID: 18507039.

Kellinsalmi M, Mönkkönen H, Mönkkönen J, et al. In vitro comparison of clodronate, pamidronate and zoledronic acid effects on rat osteoclasts and human stem cell-derived osteoblasts. Basic Clin Pharmacol Toxicol. 2005 Dec;97(6):382-91. PMID: 16364054.

Reszka AA, Rodan GA. Mechanism of action of bisphosphonates. Curr Osteoporos Rep. 2003 Sep;1(2):45-52. PMID: 16036064.

Rogers MJ. New insights into the molecular mechanisms of action of bisphosphonates. Curr Pharm Des. 2003;9(32):2643-58. PMID: 14529538.

Lehenkari PP, Kellinsalmi M, Näpänkangas JP, et al. Further insight into mechanism of action of clodronate: inhibition of mitochondrial ADP/ATP translocase by a nonhydrolyzable, adenine-containing metabolite. Mol Pharmacol. 2002 May;61(5):1255-62. PMID: 11961144.

Sato A, Nakashima H, Nakashima M, et al. Involvement of the TNF and FasL produced by CD11b Kupffer cells/macrophages in CCl4-induced acute hepatic injury. PLoS One. 2014 Mar 25;9(3):e92515. PMID: 24667392.

Kimura K, Nakamura Y, Inaba Y, et al. Histidine augments the suppression of hepatic glucose production by central insulin action. Diabetes. 2013 Jul;62(7):2266-2277. PMID: 23474485.

" T Not dangerous goods.

LKT A4675 Alternariol 1 mg 93.8 Mycotoxin produced by Alternaria; topoisomerase I and II inhibitor, potential ER agonist. 3,4,4'-Trihydroxy-6'-methyl-2-biphenylcarboxylic acid, gamma lactone 641-38-3 ≥98% 258.23 C14H10O5 CC1=CC(=CC2=C1C3=CC(=CC(=C3C(=O)O2)O)O)O Ambient 4°C Soluble in DMSO, ethanol and methanol, "Frizzell C, Ndossi D, Kalayou S, et al. An in vitro investigation of endocrine disrupting effects of the mycotoxin alternariol. Toxicol Appl Pharmacol. 2013 Aug 15;271(1):64-71. PMID: 23665424.

Solhaug A, Holme JA, Haglund K, et al. Alternariol induces abnormal nuclear morphology and cell cycle arrest in murine RAW 264.7 macrophages. Toxicol Lett. 2013 May 10;219(1):8-17. PMID: 23454835.

Broggi L, Reynoso C, Resnik S, et al. Occurrence of alternariol and alternariol monomethyl ether in beverages from the Entre Rios Province market, Argentina. Mycotoxin Res. 2013 Feb;29(1):17-22. PMID: 23334721.

Scott PM, Zhao W, Feng S, et al. Alternaria toxins alternariol and alternariol monomethyl ether in grain foods in Canada. Mycotoxin Res. 2012 Nov;28(4):261-6. PMID: 23087499.

Solhaug A, Vines LL, Ivanova L, et al. Mechanisms involved in alternariol-induced cell cycle arrest. Mutat Res. 2012 Oct-Nov;738-739:1-11. PMID: 23031795.

Zhao J, Liu K, Lu J, et al. Alternariol induces DNA polymerase β expression through the PKA-CREB signaling pathway. Int J Oncol. 2012 Jun;40(6):1923-8. PMID: 22406678.

Fehr M, Pahlke G, Fritz J, et al. Alternariol acts as a topoisomerase poison, preferentially affecting the IIalpha isoform. Mol Nutr Food Res. 2009 Apr;53(4):441-51. PMID: 18727009.

" Repr. 2 "UN number: 3462     Class:  6.1     Packing group:  II

Proper shipping name:  Toxins, extracted from living sources, solid, n.o.s. (Alternariol)     "

LKT A4675 Alternariol 5 mg 375.1 Mycotoxin produced by Alternaria; topoisomerase I and II inhibitor, potential ER agonist. 3,4,4'-Trihydroxy-6'-methyl-2-biphenylcarboxylic acid, gamma lactone 641-38-3 ≥98% 258.23 C14H10O5 CC1=CC(=CC2=C1C3=CC(=CC(=C3C(=O)O2)O)O)O Ambient 4°C Soluble in DMSO, ethanol and methanol, "Frizzell C, Ndossi D, Kalayou S, et al. An in vitro investigation of endocrine disrupting effects of the mycotoxin alternariol. Toxicol Appl Pharmacol. 2013 Aug 15;271(1):64-71. PMID: 23665424.

Solhaug A, Holme JA, Haglund K, et al. Alternariol induces abnormal nuclear morphology and cell cycle arrest in murine RAW 264.7 macrophages. Toxicol Lett. 2013 May 10;219(1):8-17. PMID: 23454835.

Broggi L, Reynoso C, Resnik S, et al. Occurrence of alternariol and alternariol monomethyl ether in beverages from the Entre Rios Province market, Argentina. Mycotoxin Res. 2013 Feb;29(1):17-22. PMID: 23334721.

Scott PM, Zhao W, Feng S, et al. Alternaria toxins alternariol and alternariol monomethyl ether in grain foods in Canada. Mycotoxin Res. 2012 Nov;28(4):261-6. PMID: 23087499.

Solhaug A, Vines LL, Ivanova L, et al. Mechanisms involved in alternariol-induced cell cycle arrest. Mutat Res. 2012 Oct-Nov;738-739:1-11. PMID: 23031795.

Zhao J, Liu K, Lu J, et al. Alternariol induces DNA polymerase β expression through the PKA-CREB signaling pathway. Int J Oncol. 2012 Jun;40(6):1923-8. PMID: 22406678.

Fehr M, Pahlke G, Fritz J, et al. Alternariol acts as a topoisomerase poison, preferentially affecting the IIalpha isoform. Mol Nutr Food Res. 2009 Apr;53(4):441-51. PMID: 18727009.

" Repr. 2 "UN number: 3462     Class:  6.1     Packing group:  II

Proper shipping name:  Toxins, extracted from living sources, solid, n.o.s. (Alternariol)     "

LKT A4678 Alternariol-9-methyl Ether 1 mg 247.8 Mycotoxin produced by Alternaria; oxidative phosphorylation inhibitor, potential ER agonist. 6H-Dibenzo(b,d)pyran-6-one, 3,7-dihydroxy-9-methoxy-1-methyl 23452-05-3 ≥98% 272.25 C15H12O5 CC1=CC(=CC2=C1C3=CC(=CC(=C3C(=O)O2)O)OC)O Ambient 4°C Soluble in DMSO, ethanol, methanol "Demuner AJ, Barbosa LC, Miranda AC, et al. The Fungal Phytotoxin Alternariol 9-Methyl Ether and Some of Its Synthetic Analogues Inhibit the Photosynthetic Electron Transport Chain. J Nat Prod. 2013 Nov 18. [Epub ahead of print]. PMID: 24245962.

Broggi L, Reynoso C, Resnik S, et al. Occurrence of alternariol and alternariol monomethyl ether in beverages from the Entre Rios Province market, Argentina. Mycotoxin Res. 2013 Feb;29(1):17-22. PMID: 23334721.

Scott PM, Zhao W, Feng S, et al. Alternaria toxins alternariol and alternariol monomethyl ether in grain foods in Canada. Mycotoxin Res. 2012 Nov;28(4):261-6. PMID: 23087499.

Bensassi F, Gallerne C, el Dein OS, et al. Mechanism of Alternariol monomethyl ether-induced mitochondrial apoptosis in human colon carcinoma cells. Toxicology. 2011 Dec 18;290(2-3):230-40. PMID: 22001388.

" Repr. 2 "UN number: 2811      Class: 6.1     Packing Group: II

Proper shipping name: Toxic solid, organic, n.o.s. (Alternariol-9-methyl ether)"

LKT A4678 Alternariol-9-methyl Ether 5 mg 984.5 Mycotoxin produced by Alternaria; oxidative phosphorylation inhibitor, potential ER agonist. 6H-Dibenzo(b,d)pyran-6-one, 3,7-dihydroxy-9-methoxy-1-methyl 23452-05-3 ≥98% 272.25 C15H12O5 CC1=CC(=CC2=C1C3=CC(=CC(=C3C(=O)O2)O)OC)O Ambient 4°C Soluble in DMSO, ethanol, methanol "Demuner AJ, Barbosa LC, Miranda AC, et al. The Fungal Phytotoxin Alternariol 9-Methyl Ether and Some of Its Synthetic Analogues Inhibit the Photosynthetic Electron Transport Chain. J Nat Prod. 2013 Nov 18. [Epub ahead of print]. PMID: 24245962.

Broggi L, Reynoso C, Resnik S, et al. Occurrence of alternariol and alternariol monomethyl ether in beverages from the Entre Rios Province market, Argentina. Mycotoxin Res. 2013 Feb;29(1):17-22. PMID: 23334721.

Scott PM, Zhao W, Feng S, et al. Alternaria toxins alternariol and alternariol monomethyl ether in grain foods in Canada. Mycotoxin Res. 2012 Nov;28(4):261-6. PMID: 23087499.

Bensassi F, Gallerne C, el Dein OS, et al. Mechanism of Alternariol monomethyl ether-induced mitochondrial apoptosis in human colon carcinoma cells. Toxicology. 2011 Dec 18;290(2-3):230-40. PMID: 22001388.

" Repr. 2 "UN number: 2811      Class: 6.1     Packing Group: II

Proper shipping name: Toxic solid, organic, n.o.s. (Alternariol-9-methyl ether)"

LKT B1603 Beauvericin 1 mg 70.2 Cyclic hexadepsipeptide mycotoxin produced by Cordyceps. 26048-05-5 ≥95% 783.95 C45H57N3O9 CC(C)C1C(=O)N(C(C(=O)OC(C(=O)N(C(C(=O)OC(C(=O)N(C(C(=O)O1)CC2=CC=CC=C2)C)C(C)C)CC3=CC=CC=C3)C)C(C)C)CC4=CC=CC=C4)C Ambient 4°C Insoluble in water.  Soluble in organic solvents. "Prosperini A, Juan-García A, Font G, et al. Beauvericin-induced cytotoxicity via ROS production and mitochondrial damage in Caco-2 cells. Toxicol Lett. 2013 Oct 24;222(2):204-11. PMID: 23850777.

Chen BF, Tsai MC, Jow GM. Induction of calcium influx from extracellular fluid by beauvericin in human leukemia cells. Biochem Biophys Res Commun. 2006 Feb 3;340(1):134-9. PMID: 16343425.

Lin HI, Lee YJ, Chen BF, et al. Involvement of Bcl-2 family, cytochrome c and caspase 3 in induction of apoptosis by beauvericin in human non-small cell lung cancer cells. Cancer Lett. 2005 Dec 18;230(2):248-59. PMID: 16297711.

Harnois DM, Que FG, Celli A, et al. Bcl-2 is overexpressed and alters the threshold for apoptosis in a cholangiocarcinoma cell line. Hepatology. 1997 Oct;26(4):884-90. PMID: 9328309.

" Not dangerous goods.

LKT B1603 Beauvericin 5 mg 281.2 Cyclic hexadepsipeptide mycotoxin produced by Cordyceps. 26048-05-5 ≥95% 783.95 C45H57N3O9 CC(C)C1C(=O)N(C(C(=O)OC(C(=O)N(C(C(=O)OC(C(=O)N(C(C(=O)O1)CC2=CC=CC=C2)C)C(C)C)CC3=CC=CC=C3)C)C(C)C)CC4=CC=CC=C4)C Ambient 4°C Insoluble in water.  Soluble in organic solvents. "Prosperini A, Juan-García A, Font G, et al. Beauvericin-induced cytotoxicity via ROS production and mitochondrial damage in Caco-2 cells. Toxicol Lett. 2013 Oct 24;222(2):204-11. PMID: 23850777.

Chen BF, Tsai MC, Jow GM. Induction of calcium influx from extracellular fluid by beauvericin in human leukemia cells. Biochem Biophys Res Commun. 2006 Feb 3;340(1):134-9. PMID: 16343425.

Lin HI, Lee YJ, Chen BF, et al. Involvement of Bcl-2 family, cytochrome c and caspase 3 in induction of apoptosis by beauvericin in human non-small cell lung cancer cells. Cancer Lett. 2005 Dec 18;230(2):248-59. PMID: 16297711.

Harnois DM, Que FG, Celli A, et al. Bcl-2 is overexpressed and alters the threshold for apoptosis in a cholangiocarcinoma cell line. Hepatology. 1997 Oct;26(4):884-90. PMID: 9328309.

" Not dangerous goods.

LKT C3576 Citreoviridin A 1 mg 107.3 Mycotoxin; F1F0 ATP synthase inhibitor. citreoviridin 25425-12-1 ≥95% 402.48 C23H30O6 CC1C(C(C(O1)(C)C=C(C)C=CC=CC=CC2=C(C(=CC(=O)O2)OC)C)O)(C)O Ambient 4°C Insoluble in water.  Soluble in ethanol, chloroform, dichloromethane, and DMSO (10 mg/mL). "Bai Y, Jiang LP, Liu XF, et al. The role of oxidative stress in citreoviridin-induced DNA damage in human liver-derived HepG2 cells. Environ Toxicol. 2013 Dec 6. [Epub ahead of print]. PMID: 24318808.

Wu YH, Hu CW, Chien CW, et al. Quantitative proteomic analysis of human lung tumor xenografts treated with the ectopic ATP synthase inhibitor citreoviridin. PLoS One. 2013 Aug 21;8(8):e70642. PMID: 23990911.

Hou H, Zhou R, Jia Q, et al. Citreoviridin enhances tumor necrosis factor-α-induced adhesion of human umbilical vein endothelial cells. Toxicol Ind Health. 2013 Mar 22. PMID: 23524880.

Chang HY, Huang HC, Huang TC, et al. Ectopic ATP synthase blockade suppresses lung adenocarcinoma growth by activating the unfolded protein response. Cancer Res. 2012 Sep 15;72(18):4696-706. PMID: 22822083.

Vieta I, Savarino A, Papa G, et al. In vitro inhibitory activity of citreoviridin against HIV-1 and an HIV-associated opportunist: Candida albicans. J Chemother. 1996 Oct;8(5):351-7. PMID: 8957714.

Sayood SF, Suh H, Wilcox CS, et al. Effect of citreoviridin and isocitreoviridin on beef heart mitochondrial ATPase. Arch Biochem Biophys. 1989 May 1;270(2):714-21. PMID: 2523213.

" T "UN number: 2811     Class: 6.1     Packing Group: II

Proper shipping name: Toxic solid, organic, n.o.s. (Citreoviridin A)"

LKT C3576 Citreoviridin A 5 mg 421.8 Mycotoxin; F1F0 ATP synthase inhibitor. citreoviridin 25425-12-1 ≥95% 402.48 C23H30O6 CC1C(C(C(O1)(C)C=C(C)C=CC=CC=CC2=C(C(=CC(=O)O2)OC)C)O)(C)O Ambient 4°C Insoluble in water.  Soluble in ethanol, chloroform, dichloromethane, and DMSO (10 mg/mL). "Bai Y, Jiang LP, Liu XF, et al. The role of oxidative stress in citreoviridin-induced DNA damage in human liver-derived HepG2 cells. Environ Toxicol. 2013 Dec 6. [Epub ahead of print]. PMID: 24318808.

Wu YH, Hu CW, Chien CW, et al. Quantitative proteomic analysis of human lung tumor xenografts treated with the ectopic ATP synthase inhibitor citreoviridin. PLoS One. 2013 Aug 21;8(8):e70642. PMID: 23990911.

Hou H, Zhou R, Jia Q, et al. Citreoviridin enhances tumor necrosis factor-α-induced adhesion of human umbilical vein endothelial cells. Toxicol Ind Health. 2013 Mar 22. PMID: 23524880.

Chang HY, Huang HC, Huang TC, et al. Ectopic ATP synthase blockade suppresses lung adenocarcinoma growth by activating the unfolded protein response. Cancer Res. 2012 Sep 15;72(18):4696-706. PMID: 22822083.

Vieta I, Savarino A, Papa G, et al. In vitro inhibitory activity of citreoviridin against HIV-1 and an HIV-associated opportunist: Candida albicans. J Chemother. 1996 Oct;8(5):351-7. PMID: 8957714.

Sayood SF, Suh H, Wilcox CS, et al. Effect of citreoviridin and isocitreoviridin on beef heart mitochondrial ATPase. Arch Biochem Biophys. 1989 May 1;270(2):714-21. PMID: 2523213.

" T "UN number: 2811     Class: 6.1     Packing Group: II

Proper shipping name: Toxic solid, organic, n.o.s. (Citreoviridin A)"

LKT D3200 Diacetoxyscirpenol 1 mg 53.4 Type A trichothecene mycotoxin produced by Fusarium. Anguidin, Anguidine 2270-40-8 ≥98% 366.41 C19H26O7 CC1=CC2C(CC1)(C3(C(C(C(C34CO4)O2)O)OC(=O)C)C)COC(=O)C Ambient 4°C Insoluble in water.  Soluble in methanol (10 mg/mL), and acetone. "Jun DY, Kim JS, Park HS, et al. Cytotoxicity of diacetoxyscirpenol is associated with apoptosis by activation of caspase-8 and interruption of cell cycle progression by down-regulation of cdk4 and cyclin B1 in human Jurkat T cells. Toxicol Appl Pharmacol. 2007 Jul 15;222(2):190-201. PMID: 17559898.

Nasri T, Bosch RR, Voorde St, et al. Differential induction of apoptosis by type A and B trichothecenes in Jurkat T-lymphocytes. Toxicol In Vitro. 2006 Sep;20(6):832-40. PMID: 16472964.

Ayral AM, Dubech N, Le Bars J, et al. In vitro effect of diacetoxyscirpenol and deoxynivalenol on microbicidal activity of murine peritoneal macrophages. Mycopathologia. 1992 Nov;120(2):121-7. PMID: 1336129.

Coppock RW, Gelberg HB, Hoffmann WE, et al. The acute toxicopathy of intravenous diacetoxyscirpenol (anguidine) administration in swine. Fundam Appl Toxicol. 1985 Dec;5(6 Pt 1):1034-49. PMID: 4092867.

" T+, Xi "UN number: 3462     Class:  6.1     Packing group:  II

Proper shipping name:  Toxins, extracted from living sources solid, n.o.s. (Diacetoxyscirpenol)"

LKT D3200 Diacetoxyscirpenol 5 mg 224.4 Type A trichothecene mycotoxin produced by Fusarium. Anguidin, Anguidine 2270-40-8 ≥98% 366.41 C19H26O7 CC1=CC2C(CC1)(C3(C(C(C(C34CO4)O2)O)OC(=O)C)C)COC(=O)C Ambient 4°C Insoluble in water.  Soluble in methanol (10 mg/mL), and acetone. "Jun DY, Kim JS, Park HS, et al. Cytotoxicity of diacetoxyscirpenol is associated with apoptosis by activation of caspase-8 and interruption of cell cycle progression by down-regulation of cdk4 and cyclin B1 in human Jurkat T cells. Toxicol Appl Pharmacol. 2007 Jul 15;222(2):190-201. PMID: 17559898.

Nasri T, Bosch RR, Voorde St, et al. Differential induction of apoptosis by type A and B trichothecenes in Jurkat T-lymphocytes. Toxicol In Vitro. 2006 Sep;20(6):832-40. PMID: 16472964.

Ayral AM, Dubech N, Le Bars J, et al. In vitro effect of diacetoxyscirpenol and deoxynivalenol on microbicidal activity of murine peritoneal macrophages. Mycopathologia. 1992 Nov;120(2):121-7. PMID: 1336129.

Coppock RW, Gelberg HB, Hoffmann WE, et al. The acute toxicopathy of intravenous diacetoxyscirpenol (anguidine) administration in swine. Fundam Appl Toxicol. 1985 Dec;5(6 Pt 1):1034-49. PMID: 4092867.

" T+, Xi "UN number: 3462     Class:  6.1     Packing group:  II

Proper shipping name:  Toxins, extracted from living sources solid, n.o.s. (Diacetoxyscirpenol)"

LKT I5752 Ionomycin, Free Acid 1 mg 43.5 Polyether Ca2+ ionophore. 56092-81-0 ≥98%, TLC, HPLC 709 C41H72O9 CC(CCC(=O)O)CC(C)CC(C)C(=O)C=C(C(C)CC(C)CC=CC(C)C(C(C)C(CC1CCC(O1)(C)C2CCC(O2)(C)C(C)O)O)O)O Ambient 4°C Soluble in DMSO (10 mg/mL), ethanol (10 mg/mL).  Insoluble in water. "Müller MS, Obel LF, Waagepetersen HS, et al. Complex actions of ionomycin in cultured cerebellar astrocytes affecting both calcium-induced calcium release and store-operated calcium entry. Neurochem Res. 2013 Jun;38(6):1260-5. PMID: 23519933.

Dedkova EN, Sigova AA, Zinchenko VP. Mechanism of action of calcium ionophores on intact cells: ionophore-resistant cells. Membr Cell Biol. 2000;13(3):357-68. PMID: 10768486

Reynolds JE, Eastman A. Intracellular calcium stores are not required for Bcl-2-mediated protection from apoptosis. J Biol Chem. 1996 Nov 1;271(44):27739-43. PMID: 8910367.

Mason MJ, Grinstein S. Ionomycin activates electrogenic Ca2+ influx in rat thymic lymphocytes. Biochem J. 1993 Nov 15;296 ( Pt 1):33-9. PMID: 8250855.

" Xn Not dangerous goods.

LKT I5752 Ionomycin, Free Acid 5 mg 164.1 Polyether Ca2+ ionophore. 56092-81-0 ≥98%, TLC, HPLC 709 C41H72O9 CC(CCC(=O)O)CC(C)CC(C)C(=O)C=C(C(C)CC(C)CC=CC(C)C(C(C)C(CC1CCC(O1)(C)C2CCC(O2)(C)C(C)O)O)O)O Ambient 4°C Soluble in DMSO (10 mg/mL), ethanol (10 mg/mL).  Insoluble in water. "Müller MS, Obel LF, Waagepetersen HS, et al. Complex actions of ionomycin in cultured cerebellar astrocytes affecting both calcium-induced calcium release and store-operated calcium entry. Neurochem Res. 2013 Jun;38(6):1260-5. PMID: 23519933.

Dedkova EN, Sigova AA, Zinchenko VP. Mechanism of action of calcium ionophores on intact cells: ionophore-resistant cells. Membr Cell Biol. 2000;13(3):357-68. PMID: 10768486

Reynolds JE, Eastman A. Intracellular calcium stores are not required for Bcl-2-mediated protection from apoptosis. J Biol Chem. 1996 Nov 1;271(44):27739-43. PMID: 8910367.

Mason MJ, Grinstein S. Ionomycin activates electrogenic Ca2+ influx in rat thymic lymphocytes. Biochem J. 1993 Nov 15;296 ( Pt 1):33-9. PMID: 8250855.

" Xn Not dangerous goods.

LKT D1760 3-Acetyl-deoxynivalenol 1 mg 144 Type A trichothecene mycotoxin produced by Fusarium. "3-Acetyl-Deoxynivalenol

3α-Acetylvomitoxin

3-Acetyl don

3-Acetyldeoxynivalenol

Dehydronivalenol monoacetate

Deoxynivalenol monoacetate

NSC 26703" 50722-38-8 ≥98% 338.35 C17H22O7 CC1=CC2C(C(C1=O)O)(C3(CC(C(C34CO4)O2)OC(=O)C)C)CO Ambient 4°C Soluble in acetonitrile, methanol (10 mg/mL) and ethyl acetate (10 mg/mL), only slightly soluble in water. "Puri KD, Zhong S. The 3ADON population of Fusarium graminearum found in North Dakota is more aggressive and produces a higher level of DON than the prevalent 15ADON population in spring wheat. Phytopathology. 2010 Oct;100(10):1007-14. PMID: 20839936.

Monbaliu S, Van Poucke C, Detavernier C, et al. Occurrence of mycotoxins in feed as analyzed by a multi-mycotoxin LC-MS/MS method. J Agric Food Chem. 2010 Jan 13;58(1):66-71. PMID: 19994896.

Gottschalk C, Barthel J, Engelhardt G, et al. Occurrence of type A trichothecenes in conventionally and organically produced oats and oat products. Mol Nutr Food Res. 2007 Dec;51(12):1547-53. PMID: 18030660.

Pestka JJ, Uzarski RL, Islam Z. Induction of apoptosis and cytokine production in the Jurkat human T cells by deoxynivalenol: role of mitogen-activated protein kinases and comparison to other 8-ketotrichothecenes. Toxicology. 2005 Jan 15;206(2):207-19. PMID: 15588914.

Ouyang YL, Azcona-Olivera JI, Pestka JJ. Effects of trichothecene structure on cytokine secretion and gene expression in murine CD4+ T-cells. Toxicology. 1995 Dec 15;104(1-3):187-202. PMID: 8560498.

Tomar RS, Blakley BR, Schiefer HB, et al. In vitro effects of 3-acetyl-deoxynivalenol on the immune response of human peripheral blood lymphocytes. Int J Immunopharmacol. 1986;8(2):125-30. PMID: 3710661.

" T, Xi, Xn, F "UN number: 2811     Class:  6.1     Packing group:  II

Proper shipping name:  Toxic solids, organic, n.o.s. (3-Acetyldeoxynivalenol)

Marine pollutant:  No,  Poison inhalation hazard:  No."

LKT D1760 3-Acetyl-deoxynivalenol 5 mg 576 Type A trichothecene mycotoxin produced by Fusarium. "3-Acetyl-Deoxynivalenol

3α-Acetylvomitoxin

3-Acetyl don

3-Acetyldeoxynivalenol

Dehydronivalenol monoacetate

Deoxynivalenol monoacetate

NSC 26703" 50722-38-8 ≥98% 338.35 C17H22O7 CC1=CC2C(C(C1=O)O)(C3(CC(C(C34CO4)O2)OC(=O)C)C)CO Ambient 4°C Soluble in acetonitrile, methanol (10 mg/mL) and ethyl acetate (10 mg/mL), only slightly soluble in water. "Puri KD, Zhong S. The 3ADON population of Fusarium graminearum found in North Dakota is more aggressive and produces a higher level of DON than the prevalent 15ADON population in spring wheat. Phytopathology. 2010 Oct;100(10):1007-14. PMID: 20839936.

Monbaliu S, Van Poucke C, Detavernier C, et al. Occurrence of mycotoxins in feed as analyzed by a multi-mycotoxin LC-MS/MS method. J Agric Food Chem. 2010 Jan 13;58(1):66-71. PMID: 19994896.

Gottschalk C, Barthel J, Engelhardt G, et al. Occurrence of type A trichothecenes in conventionally and organically produced oats and oat products. Mol Nutr Food Res. 2007 Dec;51(12):1547-53. PMID: 18030660.

Pestka JJ, Uzarski RL, Islam Z. Induction of apoptosis and cytokine production in the Jurkat human T cells by deoxynivalenol: role of mitogen-activated protein kinases and comparison to other 8-ketotrichothecenes. Toxicology. 2005 Jan 15;206(2):207-19. PMID: 15588914.

Ouyang YL, Azcona-Olivera JI, Pestka JJ. Effects of trichothecene structure on cytokine secretion and gene expression in murine CD4+ T-cells. Toxicology. 1995 Dec 15;104(1-3):187-202. PMID: 8560498.

Tomar RS, Blakley BR, Schiefer HB, et al. In vitro effects of 3-acetyl-deoxynivalenol on the immune response of human peripheral blood lymphocytes. Int J Immunopharmacol. 1986;8(2):125-30. PMID: 3710661.

" T, Xi, Xn, F "UN number: 2811     Class:  6.1     Packing group:  II

Proper shipping name:  Toxic solids, organic, n.o.s. (3-Acetyldeoxynivalenol)

Marine pollutant:  No,  Poison inhalation hazard:  No."

LKT D1761 15-Acetyl-deoxynivalenol 1 mg 258 Type A trichothecene mycotoxin produced by Fusarium. "15-Acetyl-deoxynivalenol

15-A-DON" 88337-96-6 ≥98%, TLC 338.35 C17H22O7 CC1=CC2C(C(C1=O)O)(C3(CC(C(C34CO4)O2)O)C)COC(=O)C Ambient 4°C Soluble in acetonitrile, methanol and ethyl acetate, only slightly soluble in water. "Puri KD, Zhong S. The 3ADON population of Fusarium graminearum found in North Dakota is more aggressive and produces a higher level of DON than the prevalent 15ADON population in spring wheat. Phytopathology. 2010 Oct;100(10):1007-14. PMID: 20839936.

Monbaliu S, Van Poucke C, Detavernier C, et al. Occurrence of mycotoxins in feed as analyzed by a multi-mycotoxin LC-MS/MS method. J Agric Food Chem. 2010 Jan 13;58(1):66-71. PMID: 19994896.

Gottschalk C, Barthel J, Engelhardt G, et al. Occurrence of type A trichothecenes in conventionally and organically produced oats and oat products. Mol Nutr Food Res. 2007 Dec;51(12):1547-53. PMID: 18030660.

Pestka JJ, Uzarski RL, Islam Z. Induction of apoptosis and cytokine production in the Jurkat human T cells by deoxynivalenol: role of mitogen-activated protein kinases and comparison to other 8-ketotrichothecenes. Toxicology. 2005 Jan 15;206(2):207-19. PMID: 15588914.

Ouyang YL, Azcona-Olivera JI, Pestka JJ. Effects of trichothecene structure on cytokine secretion and gene expression in murine CD4+ T-cells. Toxicology. 1995 Dec 15;104(1-3):187-202. PMID: 8560498.

" T, Xi, Xn, F "UN number: 3462     Class: 6.1     Packing Group: II

Proper shipping name: Toxins, extracted from living sources, solid, n.o.s. (15-Acetyldeoxynivalenol)"

LKT D1761 15-Acetyl-deoxynivalenol 5 mg 1021.2 Type A trichothecene mycotoxin produced by Fusarium. "15-Acetyl-deoxynivalenol

15-A-DON" 88337-96-6 ≥98%, TLC 338.35 C17H22O7 CC1=CC2C(C(C1=O)O)(C3(CC(C(C34CO4)O2)O)C)COC(=O)C Ambient 4°C Soluble in acetonitrile, methanol and ethyl acetate, only slightly soluble in water. "Puri KD, Zhong S. The 3ADON population of Fusarium graminearum found in North Dakota is more aggressive and produces a higher level of DON than the prevalent 15ADON population in spring wheat. Phytopathology. 2010 Oct;100(10):1007-14. PMID: 20839936.

Monbaliu S, Van Poucke C, Detavernier C, et al. Occurrence of mycotoxins in feed as analyzed by a multi-mycotoxin LC-MS/MS method. J Agric Food Chem. 2010 Jan 13;58(1):66-71. PMID: 19994896.

Gottschalk C, Barthel J, Engelhardt G, et al. Occurrence of type A trichothecenes in conventionally and organically produced oats and oat products. Mol Nutr Food Res. 2007 Dec;51(12):1547-53. PMID: 18030660.

Pestka JJ, Uzarski RL, Islam Z. Induction of apoptosis and cytokine production in the Jurkat human T cells by deoxynivalenol: role of mitogen-activated protein kinases and comparison to other 8-ketotrichothecenes. Toxicology. 2005 Jan 15;206(2):207-19. PMID: 15588914.

Ouyang YL, Azcona-Olivera JI, Pestka JJ. Effects of trichothecene structure on cytokine secretion and gene expression in murine CD4+ T-cells. Toxicology. 1995 Dec 15;104(1-3):187-202. PMID: 8560498.

" T, Xi, Xn, F "UN number: 3462     Class: 6.1     Packing Group: II

Proper shipping name: Toxins, extracted from living sources, solid, n.o.s. (15-Acetyldeoxynivalenol)"

LKT N1858 Neosolaniol 1 mg 144 Type A trichothecene mycotoxin produced by Fusarium. "8-Hydroxydiacetoxyscirpenol

Trichothec-9-ene-3-alpha,4-beta,8-alpha,15-tetrol, 12,13-epoxy-, 4,15-diacetate" 36519-25-2 ≥98% 382.4 C19H26O8 CC1=CC2C(CC1O)(C3(C(C(C(C34CO4)O2)O)OC(=O)C)C)COC(=O)C Ambient 4°C Soluble in DMSO (10 mg/mL), methanol (10 mg/mL). "Monbaliu S, Van Poucke C, Detavernier C, et al. Occurrence of mycotoxins in feed as analyzed by a multi-mycotoxin LC-MS/MS method. J Agric Food Chem. 2010 Jan 13;58(1):66-71. PMID: 19994896.

Gottschalk C, Barthel J, Engelhardt G, et al. Occurrence of type A trichothecenes in conventionally and organically produced oats and oat products. Mol Nutr Food Res. 2007 Dec;51(12):1547-53. PMID: 18030660.

Altomare C, Ritieni A, Perrone G, et al. Production of neosolaniol by Fusarium tumidum. Mycopathologia. 1995 Jun;130(3):179-84. PMID: 7566071.

Janse van Rensburg DF, Thiel PG, Jaskiewicz K. Short-term effects of two fusarium toxins, diacetoxyscirpenol and neosolaniol monoacetate, in male Wistar rats. Food Chem Toxicol. 1987 Oct;25(10):767-71. PMID: 3679023.

" T+, Xi, Xn, F "UN number: 2811     Class: 6.1     Packing Group: II

Proper shipping name: Toxic solid, organic, n.o.s. (Neosolaniol)"

LKT N1858 Neosolaniol 5 mg 576 Type A trichothecene mycotoxin produced by Fusarium. "8-Hydroxydiacetoxyscirpenol

Trichothec-9-ene-3-alpha,4-beta,8-alpha,15-tetrol, 12,13-epoxy-, 4,15-diacetate" 36519-25-2 ≥98% 382.4 C19H26O8 CC1=CC2C(CC1O)(C3(C(C(C(C34CO4)O2)O)OC(=O)C)C)COC(=O)C Ambient 4°C Soluble in DMSO (10 mg/mL), methanol (10 mg/mL). "Monbaliu S, Van Poucke C, Detavernier C, et al. Occurrence of mycotoxins in feed as analyzed by a multi-mycotoxin LC-MS/MS method. J Agric Food Chem. 2010 Jan 13;58(1):66-71. PMID: 19994896.

Gottschalk C, Barthel J, Engelhardt G, et al. Occurrence of type A trichothecenes in conventionally and organically produced oats and oat products. Mol Nutr Food Res. 2007 Dec;51(12):1547-53. PMID: 18030660.

Altomare C, Ritieni A, Perrone G, et al. Production of neosolaniol by Fusarium tumidum. Mycopathologia. 1995 Jun;130(3):179-84. PMID: 7566071.

Janse van Rensburg DF, Thiel PG, Jaskiewicz K. Short-term effects of two fusarium toxins, diacetoxyscirpenol and neosolaniol monoacetate, in male Wistar rats. Food Chem Toxicol. 1987 Oct;25(10):767-71. PMID: 3679023.

" T+, Xi, Xn, F "UN number: 2811     Class: 6.1     Packing Group: II

Proper shipping name: Toxic solid, organic, n.o.s. (Neosolaniol)"

LKT O4531 Oligomycin A 1 mg 77.1 Macrolide; F1F0 ATP synthase inhibitor. 579-13-5 ≥97%, TLC, HPLC 791.06 C45H74O11 CCC1CCC2C(C(C(C3(O2)CCC(C(O3)CC(C)O)C)C)OC(=O)C=CC(C(C(C(=O)C(C(C(C(=O)C(C(C(CC=CC=C1)C)O)(C)O)C)O)C)C)O)C)C Ambient 4°C Soluble in DMSO, ethanol, acetone. "He L, Jang JH, Choi HG, et al. Oligomycin A enhances apoptotic effect of TRAIL through CHOP-mediated death receptor 5 expression. Mol Carcinog. 2013 Feb;52(2):85-93. PMID: 23335397.

Ponnala S, Chetty C, Veeravalli KK, et al. Metabolic remodeling precedes mitochondrial outer membrane permeabilization in human glioma xenograft cells. Int J Oncol. 2012 Feb;40(2):509-18. PMID: 22076676.

Yang PW, Li MG, Zhao JY, et al. Oligomycins A and C, major secondary metabolites isolated from the newly isolated strain Streptomyces diastaticus. Folia Microbiol (Praha). 2010 Jan;55(1):10-6. PMID: 20336498.

" Not dangerous goods.