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LKT Labs M5675 Endogenous peptide

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LKT Labs 是一家专注于防癌抗癌特殊化学品研究和开发的公司。主要提供:癌症药物、药物发现试剂盒、天然产物、广泛的生命科学研究试剂、定制合成。
美国LKT Labs 是1988年在美国成立的,为全球提供先端的药物研发试剂、试剂盒、委托合成,并为药物生产企业提供原料,最近几年在农药、水产养殖业有很大程度的开发。LKT Labs M5675 Endogenous peptide

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LKT Labs 是一家专注于防癌抗癌特殊化学品研究和开发的公司。主要提供:癌症药物、药物发现试剂盒、天然产物、广泛的生命科学研究试剂、定制合成。
美国LKT Labs 是1988年在美国成立的,为全球提供先端的药物研发试剂、试剂盒、委托合成,并为药物生产企业提供原料,最近几年在农药、水产养殖业有很大程度的开发。在LKT Labs 可以找到在其他地方找不到的产品。

LKT Labs M5675 Endogenous peptide

LKT Labs M5675 Endogenous peptide

 

LKT L1884 Levosimendan 250 mg 149.5 Ca2+ sensitizer; ATP-sensitive K+ channel activator, troponin C stabilizer, PDE inhibitor. "Mesoxalonitrile (-)-(p((R)-1,4,5,6-tetrahydro-4-methyl-6-

oxo-3-pyridazinyl)phenyl)hydrazone" Simdax 141505-33-1 ≥98% 280.28 C14H12N6O CC1CC(=O)NN=C1C2=CC=C(C=C2)NN=C(C#N)C#N Store in a cool, dry place. Protect from direct light. Ambient 4°C Insoluble in water (0.04 mg/ml), soluble in DMSO (>50 mg/ml). "Pathak A, Lebrin M, Vaccaro A, et al. Pharmacology of levosimendan: inotropic, vasodilatory and cardioprotective effects. J Clin Pharm Ther. 2013 Oct;38(5):341-9. PMID: 23594161.

 

Malmberg M, Vähäsilta T, Saraste A, et al. Intracoronary Levosimendan during Ischemia Prevents Myocardial Apoptosis. Front Physiol. 2012 Feb 14;3:17. PMID: 22347864.

 

Papp Z, Édes I, Fruhwald S, et al. Levosimendan: molecular mechanisms and clinical implications: consensus of experts on the mechanisms of action of levosimendan. Int J Cardiol. 2012 Aug 23;159(2):82-7. PMID: 21784540.

 

Milligan DJ, Fields AM. Levosimendan: calcium sensitizer and inodilator. Anesthesiol Clin. 2010 Dec;28(4):753-60. PMID: 21074750.

" Not dangerous goods.

LKT L1884 Levosimendan 1 g 475.7 Ca2+ sensitizer; ATP-sensitive K+ channel activator, troponin C stabilizer, PDE inhibitor. "Mesoxalonitrile (-)-(p((R)-1,4,5,6-tetrahydro-4-methyl-6-

oxo-3-pyridazinyl)phenyl)hydrazone" Simdax 141505-33-1 ≥98% 280.28 C14H12N6O CC1CC(=O)NN=C1C2=CC=C(C=C2)NN=C(C#N)C#N Store in a cool, dry place. Protect from direct light. Ambient 4°C Insoluble in water (0.04 mg/ml), soluble in DMSO (>50 mg/ml). "Pathak A, Lebrin M, Vaccaro A, et al. Pharmacology of levosimendan: inotropic, vasodilatory and cardioprotective effects. J Clin Pharm Ther. 2013 Oct;38(5):341-9. PMID: 23594161.

 

Malmberg M, Vähäsilta T, Saraste A, et al. Intracoronary Levosimendan during Ischemia Prevents Myocardial Apoptosis. Front Physiol. 2012 Feb 14;3:17. PMID: 22347864.

 

Papp Z, Édes I, Fruhwald S, et al. Levosimendan: molecular mechanisms and clinical implications: consensus of experts on the mechanisms of action of levosimendan. Int J Cardiol. 2012 Aug 23;159(2):82-7. PMID: 21784540.

 

Milligan DJ, Fields AM. Levosimendan: calcium sensitizer and inodilator. Anesthesiol Clin. 2010 Dec;28(4):753-60. PMID: 21074750.

" Not dangerous goods.

LKT T0251 Tamsulosin Hydrochloride 10 mg 75 α1-adrenergic antagonist. 5-[(2R)-2-[[2-(2-Ethoxy-phenoxy)-ethyl]]amino]propyl]-2-methoxybenzenesulfonamide hydrochloride Flomax; Harnal; Pradif 106463-17-6 ≥98% 444.98 C20H28N2O5S HCl CCOC1=CC=CC=C1OCCNC(C)CC2=CC(=C(C=C2)OC)S(=O)(=O)N.Cl Ambient 4°C Slightly soluble in water to 10 mM. Weakly soluble in methanol. DMSO to 100 mM. "Okutsu H, Matsumoto S, Ohtake A, et al. Effect of tamsulosin on bladder blood flow and bladder function in a rat model of bladder over distention/emptying induced bladder overactivity. J Urol. 2011 Dec;186(6):2470-7. PMID: 22019173.

 

Barkin J. Review of dutasteride/tamsulosin fixed-dose combination for the treatment of benign prostatic hyperplasia: efficacy, safety, and patient acceptability. Patient Prefer Adherence. 2011;5:483-90. PMID: 22003286.

 

Rajpathy J, Aswathaman K, Sinha M, et al. An in vitro study on human ureteric smooth muscle with the alpha1-adrenoceptor subtype blocker, tamsulosin. BJU Int. 2008 Dec;102(11):1743-5. PMID: 18778345.

" Xn Not dangerous goods.

LKT T0251 Tamsulosin Hydrochloride 25 mg 127.5 α1-adrenergic antagonist. 5-[(2R)-2-[[2-(2-Ethoxy-phenoxy)-ethyl]]amino]propyl]-2-methoxybenzenesulfonamide hydrochloride Flomax; Harnal; Pradif 106463-17-6 ≥98% 444.98 C20H28N2O5S HCl CCOC1=CC=CC=C1OCCNC(C)CC2=CC(=C(C=C2)OC)S(=O)(=O)N.Cl Ambient 4°C Slightly soluble in water to 10 mM. Weakly soluble in methanol. DMSO to 100 mM. "Okutsu H, Matsumoto S, Ohtake A, et al. Effect of tamsulosin on bladder blood flow and bladder function in a rat model of bladder over distention/emptying induced bladder overactivity. J Urol. 2011 Dec;186(6):2470-7. PMID: 22019173.

 

Barkin J. Review of dutasteride/tamsulosin fixed-dose combination for the treatment of benign prostatic hyperplasia: efficacy, safety, and patient acceptability. Patient Prefer Adherence. 2011;5:483-90. PMID: 22003286.

 

Rajpathy J, Aswathaman K, Sinha M, et al. An in vitro study on human ureteric smooth muscle with the alpha1-adrenoceptor subtype blocker, tamsulosin. BJU Int. 2008 Dec;102(11):1743-5. PMID: 18778345.

" Xn Not dangerous goods.

LKT T0251 Tamsulosin Hydrochloride 100 mg 328.1 α1-adrenergic antagonist. 5-[(2R)-2-[[2-(2-Ethoxy-phenoxy)-ethyl]]amino]propyl]-2-methoxybenzenesulfonamide hydrochloride Flomax; Harnal; Pradif 106463-17-6 ≥98% 444.98 C20H28N2O5S HCl CCOC1=CC=CC=C1OCCNC(C)CC2=CC(=C(C=C2)OC)S(=O)(=O)N.Cl Ambient 4°C Slightly soluble in water to 10 mM. Weakly soluble in methanol. DMSO to 100 mM. "Okutsu H, Matsumoto S, Ohtake A, et al. Effect of tamsulosin on bladder blood flow and bladder function in a rat model of bladder over distention/emptying induced bladder overactivity. J Urol. 2011 Dec;186(6):2470-7. PMID: 22019173.

 

Barkin J. Review of dutasteride/tamsulosin fixed-dose combination for the treatment of benign prostatic hyperplasia: efficacy, safety, and patient acceptability. Patient Prefer Adherence. 2011;5:483-90. PMID: 22003286.

 

Rajpathy J, Aswathaman K, Sinha M, et al. An in vitro study on human ureteric smooth muscle with the alpha1-adrenoceptor subtype blocker, tamsulosin. BJU Int. 2008 Dec;102(11):1743-5. PMID: 18778345.

" Xn Not dangerous goods.

LKT L1980 Leucokinin I 1 mg 60 Peptide found in insects. 104600-89-7 ≥95% 891.93 C41H52N11O12 CC(C(=O)NC(CC1=CC=CC=C1)C(=O)NC(CC(=O)N)C(=O)NC(CO)C(=O)NC(CC2=CNC3=CC=CC=C32)C(=O)NCC(=O)N)NC(=O)C4CCCN4C(=O)C(CC(=O)O)N Ambient -20°C Radford JC, Terhzaz S, Cabrero P, et al. Functional characterisation of the Anopheles leucokinins and their cognate G-protein coupled receptor. J Exp Biol. 2004 Dec;207(Pt 26):4573-86. PMID: 15579553. Not dangerous goods.

LKT L1980 Leucokinin I 2 mg 101.9 Peptide found in insects. 104600-89-7 ≥95% 891.93 C41H52N11O12 CC(C(=O)NC(CC1=CC=CC=C1)C(=O)NC(CC(=O)N)C(=O)NC(CO)C(=O)NC(CC2=CNC3=CC=CC=C32)C(=O)NCC(=O)N)NC(=O)C4CCCN4C(=O)C(CC(=O)O)N Ambient -20°C Radford JC, Terhzaz S, Cabrero P, et al. Functional characterisation of the Anopheles leucokinins and their cognate G-protein coupled receptor. J Exp Biol. 2004 Dec;207(Pt 26):4573-86. PMID: 15579553. Not dangerous goods.

LKT L1980 Leucokinin I 5 mg 180 Peptide found in insects. 104600-89-7 ≥95% 891.93 C41H52N11O12 CC(C(=O)NC(CC1=CC=CC=C1)C(=O)NC(CC(=O)N)C(=O)NC(CO)C(=O)NC(CC2=CNC3=CC=CC=C32)C(=O)NCC(=O)N)NC(=O)C4CCCN4C(=O)C(CC(=O)O)N Ambient -20°C Radford JC, Terhzaz S, Cabrero P, et al. Functional characterisation of the Anopheles leucokinins and their cognate G-protein coupled receptor. J Exp Biol. 2004 Dec;207(Pt 26):4573-86. PMID: 15579553. Not dangerous goods.

LKT L1981 Leucokinin VIII 1 mg 60 Peptide found in insects. ≥95% 872.94 C42H52N10O11 Ambient -20°C "Weng XH, Piermarini PM, Yamahiro A, et al. Gap junctions in Malpighian tubules of Aedes aegypti. J Exp Biol. 2008 Feb;211(Pt 3):409-22. PMID: 18203997.

 

Yu MJ, Beyenbach KW. Leucokinin activates Ca(2+)-dependent signal pathway in principal cells of Aedes aegypti Malpighian tubules. Am J Physiol Renal Physiol. 2002 Sep;283(3):F499-508. PMID: 12167601.

 

Wang S, Rubenfeld A, Hayes T, et al. Leucokinin increases paracellular permeability in insect Malpighian tubules. J Exp Biol. 1996;199(Pt 11):2537-42. PMID: 9320463.

" Not dangerous goods.

LKT L1981 Leucokinin VIII 2 mg 101.9 Peptide found in insects. ≥95% 872.94 C42H52N10O11 Ambient -20°C "Weng XH, Piermarini PM, Yamahiro A, et al. Gap junctions in Malpighian tubules of Aedes aegypti. J Exp Biol. 2008 Feb;211(Pt 3):409-22. PMID: 18203997.

 

Yu MJ, Beyenbach KW. Leucokinin activates Ca(2+)-dependent signal pathway in principal cells of Aedes aegypti Malpighian tubules. Am J Physiol Renal Physiol. 2002 Sep;283(3):F499-508. PMID: 12167601.

 

Wang S, Rubenfeld A, Hayes T, et al. Leucokinin increases paracellular permeability in insect Malpighian tubules. J Exp Biol. 1996;199(Pt 11):2537-42. PMID: 9320463.

" Not dangerous goods.

LKT L1981 Leucokinin VIII 5 mg 180 Peptide found in insects. ≥95% 872.94 C42H52N10O11 Ambient -20°C "Weng XH, Piermarini PM, Yamahiro A, et al. Gap junctions in Malpighian tubules of Aedes aegypti. J Exp Biol. 2008 Feb;211(Pt 3):409-22. PMID: 18203997.

 

Yu MJ, Beyenbach KW. Leucokinin activates Ca(2+)-dependent signal pathway in principal cells of Aedes aegypti Malpighian tubules. Am J Physiol Renal Physiol. 2002 Sep;283(3):F499-508. PMID: 12167601.

 

Wang S, Rubenfeld A, Hayes T, et al. Leucokinin increases paracellular permeability in insect Malpighian tubules. J Exp Biol. 1996;199(Pt 11):2537-42. PMID: 9320463.

" Not dangerous goods.

LKT L1983 Leucomyosuppressin 2.5 mg 144 Peptide found in insects. LMS 106884-19-9 ≥95% 1257.44 C59H84N16O15 CC(C)CC(C(=O)NC(CCCN=C(N)N)C(=O)NC(CC1=CC=CC=C1)C(=O)N)NC(=O)C(CC2=CC=CC=C2)NC(=O)C(C(C)C)NC(=O)C(CC3=CN=CN3)NC(=O)C(CC(=O)O)NC(=O)C(C(C)C)NC(=O)C(CC(=O)O)NC(=O)C4CCC(=O)N4 Ambient -20°C "Maestro JL, Tobe SS, Belles X. Leucomyosuppressin modulates cardiac rhythm in the cockroach Blattella germanica. J Insect Physiol. 2011 Dec;57(12):1677-81. PMID: 21925505.

 

Matthews HJ, Audsley N, Weaver RJ. In vitro and in vivo effects of myo-active peptides on larvae of the tomato moth Lacanobia oleracea and the cotton leaf worm Spodoptera littoralis (Lepidoptera; Noctuidae). Arch Insect Biochem Physiol. 2008 Oct;69(2):60-9. PMID: 18780345.

 

Predel R, Rapus J, Eckert M. Myoinhibitory neuropeptides in the American cockroach. Peptides. 2001 Feb;22(2):199-208. PMID: 11179813.

" Not dangerous goods.

LKT L1983 Leucomyosuppressin 1 mg 81 Peptide found in insects. LMS 106884-19-9 ≥95% 1257.44 C59H84N16O15 CC(C)CC(C(=O)NC(CCCN=C(N)N)C(=O)NC(CC1=CC=CC=C1)C(=O)N)NC(=O)C(CC2=CC=CC=C2)NC(=O)C(C(C)C)NC(=O)C(CC3=CN=CN3)NC(=O)C(CC(=O)O)NC(=O)C(C(C)C)NC(=O)C(CC(=O)O)NC(=O)C4CCC(=O)N4 Ambient -20°C "Maestro JL, Tobe SS, Belles X. Leucomyosuppressin modulates cardiac rhythm in the cockroach Blattella germanica. J Insect Physiol. 2011 Dec;57(12):1677-81. PMID: 21925505.

 

Matthews HJ, Audsley N, Weaver RJ. In vitro and in vivo effects of myo-active peptides on larvae of the tomato moth Lacanobia oleracea and the cotton leaf worm Spodoptera littoralis (Lepidoptera; Noctuidae). Arch Insect Biochem Physiol. 2008 Oct;69(2):60-9. PMID: 18780345.

 

Predel R, Rapus J, Eckert M. Myoinhibitory neuropeptides in the American cockroach. Peptides. 2001 Feb;22(2):199-208. PMID: 11179813.

" Not dangerous goods.

LKT L1983 Leucomyosuppressin 0.5 mg 48 Peptide found in insects. LMS 106884-19-9 ≥95% 1257.44 C59H84N16O15 CC(C)CC(C(=O)NC(CCCN=C(N)N)C(=O)NC(CC1=CC=CC=C1)C(=O)N)NC(=O)C(CC2=CC=CC=C2)NC(=O)C(C(C)C)NC(=O)C(CC3=CN=CN3)NC(=O)C(CC(=O)O)NC(=O)C(C(C)C)NC(=O)C(CC(=O)O)NC(=O)C4CCC(=O)N4 Ambient -20°C "Maestro JL, Tobe SS, Belles X. Leucomyosuppressin modulates cardiac rhythm in the cockroach Blattella germanica. J Insect Physiol. 2011 Dec;57(12):1677-81. PMID: 21925505.

 

Matthews HJ, Audsley N, Weaver RJ. In vitro and in vivo effects of myo-active peptides on larvae of the tomato moth Lacanobia oleracea and the cotton leaf worm Spodoptera littoralis (Lepidoptera; Noctuidae). Arch Insect Biochem Physiol. 2008 Oct;69(2):60-9. PMID: 18780345.

 

Predel R, Rapus J, Eckert M. Myoinhibitory neuropeptides in the American cockroach. Peptides. 2001 Feb;22(2):199-208. PMID: 11179813.

" Not dangerous goods.

LKT L2876 Luteinizing Hormone Releasing Hormone III, lamprey 1 mg 60 Peptide hormone found in eels; GnRH agonist, weak ERK1/2 and p38 MAPK activator. LHRH-III, lamprey ≥98% 1259.4 C59H75N18O14 Ambient -20°C "Yang D, Caraty A, Dupont J. Molecular mechanisms involved in LH release by the ovine pituitary cells. Domest Anim Endocrinol. 2005 Oct;29(3):488-507. PMID: 16153499.

 

Yu WH, Karanth S, Walczewska A, et al. A hypothalamic follicle-stimulating hormone-releasing decapeptide in the rat. Proc Natl Acad Sci U S A. 1997 Aug 19;94(17):9499-503. PMID: 9256511.

" Not dangerous goods.

LKT L2876 Luteinizing Hormone Releasing Hormone III, lamprey 2 mg 101.9 Peptide hormone found in eels; GnRH agonist, weak ERK1/2 and p38 MAPK activator. LHRH-III, lamprey ≥98% 1259.4 C59H75N18O14 Ambient -20°C "Yang D, Caraty A, Dupont J. Molecular mechanisms involved in LH release by the ovine pituitary cells. Domest Anim Endocrinol. 2005 Oct;29(3):488-507. PMID: 16153499.

 

Yu WH, Karanth S, Walczewska A, et al. A hypothalamic follicle-stimulating hormone-releasing decapeptide in the rat. Proc Natl Acad Sci U S A. 1997 Aug 19;94(17):9499-503. PMID: 9256511.

" Not dangerous goods.

LKT L2876 Luteinizing Hormone Releasing Hormone III, lamprey 5 mg 180 Peptide hormone found in eels; GnRH agonist, weak ERK1/2 and p38 MAPK activator. LHRH-III, lamprey ≥98% 1259.4 C59H75N18O14 Ambient -20°C "Yang D, Caraty A, Dupont J. Molecular mechanisms involved in LH release by the ovine pituitary cells. Domest Anim Endocrinol. 2005 Oct;29(3):488-507. PMID: 16153499.

 

Yu WH, Karanth S, Walczewska A, et al. A hypothalamic follicle-stimulating hormone-releasing decapeptide in the rat. Proc Natl Acad Sci U S A. 1997 Aug 19;94(17):9499-503. PMID: 9256511.

" Not dangerous goods.

LKT L3250 D-Limonene 500 mL 72.8 Terpene found in the rind of various citrus fruits. (+)-4-Isopropenyl-1-methylcyclohexene (+)-Dipentene; (+)-Limonene; (+)-R-Limonene; (+)-α-Limonene 5989-27-5 ≥96% 136.23 C10H16 CC1=CCC(CC1)C(=C)C Ambient Ambient Insoluble in water. "Zhang XZ, Wang L, Liu DW, Tang GY, Zhang HY. Synergistic Inhibitory Effect of Berberine and d-Limonene on Human Gastric Carcinoma Cell Line MGC803. J Med Food. 2014 Sep;17(9):955-62. PMID: 25045784.

 

Rehman MU, Tahir M, Khan AQ, et al. D-limonene suppresses doxorubicin-induced oxidative stress and inflammation via repression of COX-2, iNOS, and NFκB in kidneys of Wistar rats. Exp Biol Med (Maywood). 2014 Apr;239(4):465-76. PMID: 24586096.

 

Jing L, Zhang Y, Fan S, et al. Preventive and ameliorating effects of citrus D-limonene on dyslipidemia and hyperglycemia in mice with high-fat diet-induced obesity. Eur J Pharmacol. 2013 Sep 5;715(1-3):46-55. PMID: 23838456.

 

Lappas CM, Lappas NT. D-Limonene modulates T lymphocyte activity and viability. Cell Immunol. 2012 Sep;279(1):30-41. PMID: 23059811.

 

Chaudhary SC, Siddiqui MS, Athar M, et al. D-Limonene modulates inflammation, oxidative stress and Ras-ERK pathway to inhibit murine skin tumorigenesis. Hum Exp Toxicol. 2012 Aug;31(8):798-811. PMID: 22318307.

 

Sun J. D-Limonene: safety and clinical applications. Altern Med Rev. 2007 Sep;12(3):259-64. PMID: 18072821.

" Xi, N "UN number: 2052   Class: 3   Packing Group: III

Proper Shipping Name: Dipentene

Marine Pollutant: Yes   Poison Inhalation Hazard: No  "

LKT T0250 Tamoxifen Citrate 500 mg 47.6 4-Hydroxytamoxifen prodrug; FIASMA, SERM, PKC inhibitor. "(Z)-2-(4-(1,2-Diphenyl-1-butenyl)phenoxy)-N,N-

dimethylethylamine citrate" Kessar; Nolvadex; Taxus; Zynoplex; Zemide 54965-24-1 ≥98% 563.64 C26H29NO C6H8O7 CCC(=C(C1=CC=CC=C1)C2=CC=C(C=C2)OCCN(C)C)C3=CC=CC=C3.C(C(=O)O)C(CC(=O)O)(C(=O)O)O Ambient Ambient Slightly soluble in water. Soluble in ethanol, methanol or acetone. "Yildiz A, Guleryuz S, Ankerst DP, et al. Protein kinase C inhibition in the treatment of mania: a double-blind, placebo-controlled trial of tamoxifen. Arch Gen Psychiatry. 2008 Mar;65(3):255-63. PMID: 18316672.

 

Krum SA, Miranda-Carboni GA, Hauschka PV, et al. Estrogen protects bone by inducing Fas ligand in osteoblasts to regulate osteoclast survival. EMBO J. 2008 Feb 6;27(3):535-45. PMID: 18219273.

 

Steiner AZ, Terplan M, Paulson RJ. Comparison of tamoxifen and clomiphene citrate for ovulation induction: a meta-analysis. Hum Reprod. 2005 Jun;20(6):1511-5. PMID: 15845599.

 

Blackwell KL, Haroon ZA, Shan S, et al. Tamoxifen inhibits angiogenesis in estrogen receptor-negative animal models. Clin Cancer Res. 2000 Nov;6(11):4359-64. PMID: 11106254.

 

Jordan VC. Fourteenth Gaddum Memorial Lecture. A current view of tamoxifen for the treatment and prevention of breast cancer. Br J Pharmacol. 1993 Oct;110(2):507-17. PMID: 8242225.

" Carc., Repr., Xn, Xi Not dangerous goods.

LKT T0250 Tamoxifen Citrate 1 g 95.1 4-Hydroxytamoxifen prodrug; FIASMA, SERM, PKC inhibitor. "(Z)-2-(4-(1,2-Diphenyl-1-butenyl)phenoxy)-N,N-

dimethylethylamine citrate" Kessar; Nolvadex; Taxus; Zynoplex; Zemide 54965-24-1 ≥98% 563.64 C26H29NO C6H8O7 CCC(=C(C1=CC=CC=C1)C2=CC=C(C=C2)OCCN(C)C)C3=CC=CC=C3.C(C(=O)O)C(CC(=O)O)(C(=O)O)O Ambient Ambient Slightly soluble in water. Soluble in ethanol, methanol or acetone. "Yildiz A, Guleryuz S, Ankerst DP, et al. Protein kinase C inhibition in the treatment of mania: a double-blind, placebo-controlled trial of tamoxifen. Arch Gen Psychiatry. 2008 Mar;65(3):255-63. PMID: 18316672.

 

Krum SA, Miranda-Carboni GA, Hauschka PV, et al. Estrogen protects bone by inducing Fas ligand in osteoblasts to regulate osteoclast survival. EMBO J. 2008 Feb 6;27(3):535-45. PMID: 18219273.

 

Steiner AZ, Terplan M, Paulson RJ. Comparison of tamoxifen and clomiphene citrate for ovulation induction: a meta-analysis. Hum Reprod. 2005 Jun;20(6):1511-5. PMID: 15845599.

 

Blackwell KL, Haroon ZA, Shan S, et al. Tamoxifen inhibits angiogenesis in estrogen receptor-negative animal models. Clin Cancer Res. 2000 Nov;6(11):4359-64. PMID: 11106254.

 

Jordan VC. Fourteenth Gaddum Memorial Lecture. A current view of tamoxifen for the treatment and prevention of breast cancer. Br J Pharmacol. 1993 Oct;110(2):507-17. PMID: 8242225.

" Carc., Repr., Xn, Xi Not dangerous goods.

LKT T0250 Tamoxifen Citrate 5 g 339.8 4-Hydroxytamoxifen prodrug; FIASMA, SERM, PKC inhibitor. "(Z)-2-(4-(1,2-Diphenyl-1-butenyl)phenoxy)-N,N-

dimethylethylamine citrate" Kessar; Nolvadex; Taxus; Zynoplex; Zemide 54965-24-1 ≥98% 563.64 C26H29NO C6H8O7 CCC(=C(C1=CC=CC=C1)C2=CC=C(C=C2)OCCN(C)C)C3=CC=CC=C3.C(C(=O)O)C(CC(=O)O)(C(=O)O)O Ambient Ambient Slightly soluble in water. Soluble in ethanol, methanol or acetone. "Yildiz A, Guleryuz S, Ankerst DP, et al. Protein kinase C inhibition in the treatment of mania: a double-blind, placebo-controlled trial of tamoxifen. Arch Gen Psychiatry. 2008 Mar;65(3):255-63. PMID: 18316672.

 

Krum SA, Miranda-Carboni GA, Hauschka PV, et al. Estrogen protects bone by inducing Fas ligand in osteoblasts to regulate osteoclast survival. EMBO J. 2008 Feb 6;27(3):535-45. PMID: 18219273.

 

Steiner AZ, Terplan M, Paulson RJ. Comparison of tamoxifen and clomiphene citrate for ovulation induction: a meta-analysis. Hum Reprod. 2005 Jun;20(6):1511-5. PMID: 15845599.

 

Blackwell KL, Haroon ZA, Shan S, et al. Tamoxifen inhibits angiogenesis in estrogen receptor-negative animal models. Clin Cancer Res. 2000 Nov;6(11):4359-64. PMID: 11106254.

 

Jordan VC. Fourteenth Gaddum Memorial Lecture. A current view of tamoxifen for the treatment and prevention of breast cancer. Br J Pharmacol. 1993 Oct;110(2):507-17. PMID: 8242225.

" Carc., Repr., Xn, Xi Not dangerous goods.

LKT T0249 Tamibarotene 10 mg 156 RARα/β agonist. Am80 94497-51-5 ≥98% 351.44 C22H25NO3 CC1(CCC(C2=C1C=CC(=C2)NC(=O)C3=CC=C(C=C3)C(=O)O)(C)C)C Ambient 4°C "Kitaoka K, Shimizu N, Ono K, et al. The retinoic acid receptor agonist Am80 increases hippocampal ADAM10 in aged SAMP8 mice. Neuropharmacology. 2013 Sep;72:58-65. PMID: 23624141

 

Yoshikawa O, Ebata Y, Tsuchiya H, et al. A retinoic acid receptor agonist tamibarotene suppresses iron accumulation in the liver. Obesity (Silver Spring). 2013 Jan;21(1):E22-5. PMID: 23404745.

 

Miyabe C, Miyabe Y, Miura NN, et al. Am80, a retinoic acid receptor agonist, ameliorates murine vasculitis through the suppression of neutrophil migration and activation. Arthritis Rheum. 2013 Feb;65(2):503-12. PMID: 23203767.

 

Fukasawa H, Nakagomi M, Yamagata N, et al. Tamibarotene: a candidate retinoid drug for Alzheimer's disease. Biol Pharm Bull. 2012;35(8):1206-12. PMID: 22863914.

 

Nishimori H, Maeda Y, Teshima T, et al. Synthetic retinoid Am80 ameliorates chronic graft-versus-host disease by down-regulating Th1 and Th17. Blood. 2012 Jan 5;119(1):285-95. PMID: 22077062.

 

Shiohira H, Kitaoka A, Shirasawa H, et al. Am80 induces neuronal differentiation in a human neuroblastoma NH-12 cell line. Int J Mol Med. 2010 Sep;26(3):393-9. PMID: 20664956.

 

Klemann C, Raveney BJ, Klemann AK, et al. Synthetic retinoid AM80 inhibits Th17 cells and ameliorates experimental autoimmune encephalomyelitis. Am J Pathol. 2009 Jun;174(6):2234-45. PMID: 19389933.

" None Not dangerous goods.

LKT T0249 Tamibarotene 50 mg 548.9 RARα/β agonist. Am80 94497-51-5 ≥98% 351.44 C22H25NO3 CC1(CCC(C2=C1C=CC(=C2)NC(=O)C3=CC=C(C=C3)C(=O)O)(C)C)C Ambient 4°C "Kitaoka K, Shimizu N, Ono K, et al. The retinoic acid receptor agonist Am80 increases hippocampal ADAM10 in aged SAMP8 mice. Neuropharmacology. 2013 Sep;72:58-65. PMID: 23624141

 

Yoshikawa O, Ebata Y, Tsuchiya H, et al. A retinoic acid receptor agonist tamibarotene suppresses iron accumulation in the liver. Obesity (Silver Spring). 2013 Jan;21(1):E22-5. PMID: 23404745.

 

Miyabe C, Miyabe Y, Miura NN, et al. Am80, a retinoic acid receptor agonist, ameliorates murine vasculitis through the suppression of neutrophil migration and activation. Arthritis Rheum. 2013 Feb;65(2):503-12. PMID: 23203767.

 

Fukasawa H, Nakagomi M, Yamagata N, et al. Tamibarotene: a candidate retinoid drug for Alzheimer's disease. Biol Pharm Bull. 2012;35(8):1206-12. PMID: 22863914.

 

Nishimori H, Maeda Y, Teshima T, et al. Synthetic retinoid Am80 ameliorates chronic graft-versus-host disease by down-regulating Th1 and Th17. Blood. 2012 Jan 5;119(1):285-95. PMID: 22077062.

 

Shiohira H, Kitaoka A, Shirasawa H, et al. Am80 induces neuronal differentiation in a human neuroblastoma NH-12 cell line. Int J Mol Med. 2010 Sep;26(3):393-9. PMID: 20664956.

 

Klemann C, Raveney BJ, Klemann AK, et al. Synthetic retinoid AM80 inhibits Th17 cells and ameliorates experimental autoimmune encephalomyelitis. Am J Pathol. 2009 Jun;174(6):2234-45. PMID: 19389933.

" None Not dangerous goods.

LKT L3362 β-Lipotropin (61-64) 5 mg 60 Peptide, β-lipotropin and met-enkephalin fragment. 60254-82-2 ≥95% 442.48 C22H26N4O6 C1=CC=C(C=C1)CC(C(=O)O)NC(=O)CNC(=O)CNC(=O)C(CC2=CC=C(C=C2)O)N Ambient -20°C "Spiess J, Mount CD, Nicholson WE, et al. NH2-terminal amino acid sequence and peptide mapping of purified human beta-lipotropin: comparison with previously proposed sequences. Proc Natl Acad Sci U S A. 1982 Aug;79(16):5071-5. PMID: 6956916.

 

Ling N, Guillemin R. Morphinomimetic activity of synthetic fragments of beta-lipotropin and analogs. Proc Natl Acad Sci U S A. 1976 Sep;73(9):3308-10. PMID: 1067621.

 

Lazarus LH, Ling N, Guillemin R. beta-Lipotropin as a prohormone for the morphinomimetic peptides endorphins and enkephalins. Proc Natl Acad Sci U S A. 1976 Jun;73(6):2156-9. PMID: 1064883.

"

LKT L3362 β-Lipotropin (61-64) 10 mg 101.9 Peptide, β-lipotropin and met-enkephalin fragment. 60254-82-2 ≥95% 442.48 C22H26N4O6 C1=CC=C(C=C1)CC(C(=O)O)NC(=O)CNC(=O)CNC(=O)C(CC2=CC=C(C=C2)O)N Ambient -20°C "Spiess J, Mount CD, Nicholson WE, et al. NH2-terminal amino acid sequence and peptide mapping of purified human beta-lipotropin: comparison with previously proposed sequences. Proc Natl Acad Sci U S A. 1982 Aug;79(16):5071-5. PMID: 6956916.

 

Ling N, Guillemin R. Morphinomimetic activity of synthetic fragments of beta-lipotropin and analogs. Proc Natl Acad Sci U S A. 1976 Sep;73(9):3308-10. PMID: 1067621.

 

Lazarus LH, Ling N, Guillemin R. beta-Lipotropin as a prohormone for the morphinomimetic peptides endorphins and enkephalins. Proc Natl Acad Sci U S A. 1976 Jun;73(6):2156-9. PMID: 1064883.

"

LKT L3362 β-Lipotropin (61-64) 25 mg 180 Peptide, β-lipotropin and met-enkephalin fragment. 60254-82-2 ≥95% 442.48 C22H26N4O6 C1=CC=C(C=C1)CC(C(=O)O)NC(=O)CNC(=O)CNC(=O)C(CC2=CC=C(C=C2)O)N Ambient -20°C "Spiess J, Mount CD, Nicholson WE, et al. NH2-terminal amino acid sequence and peptide mapping of purified human beta-lipotropin: comparison with previously proposed sequences. Proc Natl Acad Sci U S A. 1982 Aug;79(16):5071-5. PMID: 6956916.

 

Ling N, Guillemin R. Morphinomimetic activity of synthetic fragments of beta-lipotropin and analogs. Proc Natl Acad Sci U S A. 1976 Sep;73(9):3308-10. PMID: 1067621.

 

Lazarus LH, Ling N, Guillemin R. beta-Lipotropin as a prohormone for the morphinomimetic peptides endorphins and enkephalins. Proc Natl Acad Sci U S A. 1976 Jun;73(6):2156-9. PMID: 1064883.

"

LKT L3374 Lisinopril Dihydrate 100 mg 47.6 Enalapril analog; ACE inhibitor. (S)-1-[N2-(1-Carboxy-3-phenylpropyl)-L-lysyl]- proline dihydrate Acerbon; Carace; Coric; Novatec; Prinil; Tensopril; Vivatec; Zestril 83915-83-7 ≥98% 441.52 C21H31N3O5 2H2O C1CC(N(C1)C(=O)C(CCCCN)NC(CCC2=CC=CC=C2)C(=O)O)C(=O)O.O.O Ambient Ambient Soluble in water (100 mg/mL) or DMSO (6.5mg/mL with heating and sonication), methanol (14 mg/mL).  Insoluble in ethanol. "Brower GL, Levick SP, Janicki JS. Inhibition of matrix metalloproteinase activity by ACE inhibitors prevents left ventricular remodeling in a rat model of heart failure. Am J Physiol Heart Circ Physiol. 2007 Jun;292(6):H3057-64. PMID: 17308006.

 

Mohammadi-Karakani A, Ghazi-Khansari M, Sotoudeh M. Lisinopril ameliorates paraquat-induced lung fibrosis. Clin Chim Acta. 2006 May;367(1-2):170-4. PMID: 16458281.

 

Goa KL, Balfour JA, Zuanetti G. Lisinopril. A review of its pharmacology and clinical efficacy in the early management of acute myocardial infarction. Drugs. 1996 Oct;52(4):564-88. PMID: 8891468.

 

Apostolakis S, Krambovitis E, Vlata Z, et al. CX3CR1 receptor is up-regulated in monocytes of coronary artery diseased patients: impact of pre-inflammatory stimuli and renin-angiotensin system modulators. Thromb Res. 2007;121(3):387-395. PMID: 17521710.

" None Not dangerous goods.

LKT L3374 Lisinopril Dihydrate 1 g 95.1 Enalapril analog; ACE inhibitor. (S)-1-[N2-(1-Carboxy-3-phenylpropyl)-L-lysyl]- proline dihydrate Acerbon; Carace; Coric; Novatec; Prinil; Tensopril; Vivatec; Zestril 83915-83-7 ≥98% 441.52 C21H31N3O5 2H2O C1CC(N(C1)C(=O)C(CCCCN)NC(CCC2=CC=CC=C2)C(=O)O)C(=O)O.O.O Ambient Ambient Soluble in water (100 mg/mL) or DMSO (6.5mg/mL with heating and sonication), methanol (14 mg/mL).  Insoluble in ethanol. "Brower GL, Levick SP, Janicki JS. Inhibition of matrix metalloproteinase activity by ACE inhibitors prevents left ventricular remodeling in a rat model of heart failure. Am J Physiol Heart Circ Physiol. 2007 Jun;292(6):H3057-64. PMID: 17308006.

 

Mohammadi-Karakani A, Ghazi-Khansari M, Sotoudeh M. Lisinopril ameliorates paraquat-induced lung fibrosis. Clin Chim Acta. 2006 May;367(1-2):170-4. PMID: 16458281.

 

Goa KL, Balfour JA, Zuanetti G. Lisinopril. A review of its pharmacology and clinical efficacy in the early management of acute myocardial infarction. Drugs. 1996 Oct;52(4):564-88. PMID: 8891468.

 

Apostolakis S, Krambovitis E, Vlata Z, et al. CX3CR1 receptor is up-regulated in monocytes of coronary artery diseased patients: impact of pre-inflammatory stimuli and renin-angiotensin system modulators. Thromb Res. 2007;121(3):387-395. PMID: 17521710.

" None Not dangerous goods.

LKT L3374 Lisinopril Dihydrate 5 g 271.7 Enalapril analog; ACE inhibitor. (S)-1-[N2-(1-Carboxy-3-phenylpropyl)-L-lysyl]- proline dihydrate Acerbon; Carace; Coric; Novatec; Prinil; Tensopril; Vivatec; Zestril 83915-83-7 ≥98% 441.52 C21H31N3O5 2H2O C1CC(N(C1)C(=O)C(CCCCN)NC(CCC2=CC=CC=C2)C(=O)O)C(=O)O.O.O Ambient Ambient Soluble in water (100 mg/mL) or DMSO (6.5mg/mL with heating and sonication), methanol (14 mg/mL).  Insoluble in ethanol. "Brower GL, Levick SP, Janicki JS. Inhibition of matrix metalloproteinase activity by ACE inhibitors prevents left ventricular remodeling in a rat model of heart failure. Am J Physiol Heart Circ Physiol. 2007 Jun;292(6):H3057-64. PMID: 17308006.

 

Mohammadi-Karakani A, Ghazi-Khansari M, Sotoudeh M. Lisinopril ameliorates paraquat-induced lung fibrosis. Clin Chim Acta. 2006 May;367(1-2):170-4. PMID: 16458281.

 

Goa KL, Balfour JA, Zuanetti G. Lisinopril. A review of its pharmacology and clinical efficacy in the early management of acute myocardial infarction. Drugs. 1996 Oct;52(4):564-88. PMID: 8891468.

 

Apostolakis S, Krambovitis E, Vlata Z, et al. CX3CR1 receptor is up-regulated in monocytes of coronary artery diseased patients: impact of pre-inflammatory stimuli and renin-angiotensin system modulators. Thromb Res. 2007;121(3):387-395. PMID: 17521710.

" None Not dangerous goods.

LKT L3454 Lincomycin Hydrochloride Monohydrate 1 g 50 Lincosamide; peptidyl transferase inhibitor, protein translation inhibitor. (2S-trans)-Methyl6,8-dideoxy-6-[[(1-methyl-4-propyl-2-pyrrolidinyl)carbonyl]-amino]-1-thio-D-erythro-α- D-galacto-octopyranoside hydrochloride monohydrate  Lincomycin hydrochloride monohydrate; Albiotic; Cillimycin; Lincomix 7179-49-9 ≥89% 461.01 C18H34N2O6S HCl H2O CCCC1CC(N(C1)C)C(=O)NC(C2C(C(C(C(O2)SC)O)O)O)C(C)O.Cl Ambient 4°C Soluble in water (50mg/mL). "Tenson T, Lovmar M, Ehrenberg M. The mechanism of action of macrolides, lincosamides and streptogramin B reveals the nascent peptide exit path in the ribosome. J Mol Biol. 2003 Jul 25;330(5):1005-14. PMID: 12860123.

 

Menninger JR. Mechanism of inhibition of protein synthesis by macrolide and lincosamide antibiotics. J Basic Clin Physiol Pharmacol. 1995;6(3-4):229-50. PMID: 8852269.

" Xi Not dangerous goods.

LKT L3454 Lincomycin Hydrochloride Monohydrate 5 g 210 Lincosamide; peptidyl transferase inhibitor, protein translation inhibitor. (2S-trans)-Methyl6,8-dideoxy-6-[[(1-methyl-4-propyl-2-pyrrolidinyl)carbonyl]-amino]-1-thio-D-erythro-α- D-galacto-octopyranoside hydrochloride monohydrate  Lincomycin hydrochloride monohydrate; Albiotic; Cillimycin; Lincomix 7179-49-9 ≥89% 461.01 C18H34N2O6S HCl H2O CCCC1CC(N(C1)C)C(=O)NC(C2C(C(C(C(O2)SC)O)O)O)C(C)O.Cl Ambient 4°C Soluble in water (50mg/mL). "Tenson T, Lovmar M, Ehrenberg M. The mechanism of action of macrolides, lincosamides and streptogramin B reveals the nascent peptide exit path in the ribosome. J Mol Biol. 2003 Jul 25;330(5):1005-14. PMID: 12860123.

 

Menninger JR. Mechanism of inhibition of protein synthesis by macrolide and lincosamide antibiotics. J Basic Clin Physiol Pharmacol. 1995;6(3-4):229-50. PMID: 8852269.

" Xi Not dangerous goods.

LKT L3454 Lincomycin Hydrochloride Monohydrate 25 g 800 Lincosamide; peptidyl transferase inhibitor, protein translation inhibitor. (2S-trans)-Methyl6,8-dideoxy-6-[[(1-methyl-4-propyl-2-pyrrolidinyl)carbonyl]-amino]-1-thio-D-erythro-α- D-galacto-octopyranoside hydrochloride monohydrate  Lincomycin hydrochloride monohydrate; Albiotic; Cillimycin; Lincomix 7179-49-9 ≥89% 461.01 C18H34N2O6S HCl H2O CCCC1CC(N(C1)C)C(=O)NC(C2C(C(C(C(O2)SC)O)O)O)C(C)O.Cl Ambient 4°C Soluble in water (50mg/mL). "Tenson T, Lovmar M, Ehrenberg M. The mechanism of action of macrolides, lincosamides and streptogramin B reveals the nascent peptide exit path in the ribosome. J Mol Biol. 2003 Jul 25;330(5):1005-14. PMID: 12860123.

 

Menninger JR. Mechanism of inhibition of protein synthesis by macrolide and lincosamide antibiotics. J Basic Clin Physiol Pharmacol. 1995;6(3-4):229-50. PMID: 8852269.

" Xi Not dangerous goods.

LKT L3550 Limonin 50 mg 91.6 Furanolactone found in citrus fruits. 8-(3-furyl)decahydro-2,2,4a,8a-tetramethyl-11H,13H- oxireno-[d]pyrano[4',3':3,3a]isobenzofuro[5,4-f][2]- benzopyran-4,6,13-(2H,5aH)-trione Evodine; Limonoic acid di-δ-lactone; limonoic acid 3,19:16,17-dilactone; Citrolimonin 1180-71-8 ≥98% 470.52 C26H30O8 CC1(C2CC(=O)C3(C(C24COC(=O)CC4O1)CCC5(C36C(O6)C(=O)OC5C7=COC=C7)C)C)C Ambient Ambient Soluble in ethanol, acetic acid, or DMSO. Slightly soluble in water. "Mahmoud MF, Gamal S, El-Fayoumi HM. Limonin attenuates hepatocellular injury following liver ischemia and reperfusion in rats via toll-like receptor dependent pathway. Eur J Pharmacol. 2014 Oct 5;740:676-82.  PMID: 24967531.

 

Hafeez F, Akram W, Shaalan EA. Mosquito larvicidal activity of citrus limonoids against Aedes albopictus. Parasitol Res. 2011 Jul;109(1):221-9. PMID: 21212981.

 

Chidambara Murthy KN, Jayaprakasha GK, et al. Citrus limonin and its glucoside inhibit colon adenocarcinoma cell proliferation through apoptosis. J Agric Food Chem. 2011 Mar 23;59(6):2314-23. PMID: 21338095.

 

Balestrieri E, Pizzimenti F, Ferlazzo A, et al. Antiviral activity of seed extract from Citrus bergamia towards human retroviruses. Bioorg Med Chem. 2011 Mar 15;19(6):2084-9. PMID: 21334901.

 

Kim W, Fan YY, Smith R, et al. Dietary curcumin and limonin suppress CD4+ T-cell proliferation and interleukin-2 production in mice. J Nutr. 2009 May;139(5):1042-8. PMID: 19321585.

" Not dangerous goods.

LKT L3550 Limonin 100 mg 152.4 Furanolactone found in citrus fruits. 8-(3-furyl)decahydro-2,2,4a,8a-tetramethyl-11H,13H- oxireno-[d]pyrano[4',3':3,3a]isobenzofuro[5,4-f][2]- benzopyran-4,6,13-(2H,5aH)-trione Evodine; Limonoic acid di-δ-lactone; limonoic acid 3,19:16,17-dilactone; Citrolimonin 1180-71-8 ≥98% 470.52 C26H30O8 CC1(C2CC(=O)C3(C(C24COC(=O)CC4O1)CCC5(C36C(O6)C(=O)OC5C7=COC=C7)C)C)C Ambient Ambient Soluble in ethanol, acetic acid, or DMSO. Slightly soluble in water. "Mahmoud MF, Gamal S, El-Fayoumi HM. Limonin attenuates hepatocellular injury following liver ischemia and reperfusion in rats via toll-like receptor dependent pathway. Eur J Pharmacol. 2014 Oct 5;740:676-82.  PMID: 24967531.

 

Hafeez F, Akram W, Shaalan EA. Mosquito larvicidal activity of citrus limonoids against Aedes albopictus. Parasitol Res. 2011 Jul;109(1):221-9. PMID: 21212981.

 

Chidambara Murthy KN, Jayaprakasha GK, et al. Citrus limonin and its glucoside inhibit colon adenocarcinoma cell proliferation through apoptosis. J Agric Food Chem. 2011 Mar 23;59(6):2314-23. PMID: 21338095.

 

Balestrieri E, Pizzimenti F, Ferlazzo A, et al. Antiviral activity of seed extract from Citrus bergamia towards human retroviruses. Bioorg Med Chem. 2011 Mar 15;19(6):2084-9. PMID: 21334901.

 

Kim W, Fan YY, Smith R, et al. Dietary curcumin and limonin suppress CD4+ T-cell proliferation and interleukin-2 production in mice. J Nutr. 2009 May;139(5):1042-8. PMID: 19321585.

" Not dangerous goods.

LKT L3550 Limonin 500 mg 498.4 Furanolactone found in citrus fruits. 8-(3-furyl)decahydro-2,2,4a,8a-tetramethyl-11H,13H- oxireno-[d]pyrano[4',3':3,3a]isobenzofuro[5,4-f][2]- benzopyran-4,6,13-(2H,5aH)-trione Evodine; Limonoic acid di-δ-lactone; limonoic acid 3,19:16,17-dilactone; Citrolimonin 1180-71-8 ≥98% 470.52 C26H30O8 CC1(C2CC(=O)C3(C(C24COC(=O)CC4O1)CCC5(C36C(O6)C(=O)OC5C7=COC=C7)C)C)C Ambient Ambient Soluble in ethanol, acetic acid, or DMSO. Slightly soluble in water. "Mahmoud MF, Gamal S, El-Fayoumi HM. Limonin attenuates hepatocellular injury following liver ischemia and reperfusion in rats via toll-like receptor dependent pathway. Eur J Pharmacol. 2014 Oct 5;740:676-82.  PMID: 24967531.

 

Hafeez F, Akram W, Shaalan EA. Mosquito larvicidal activity of citrus limonoids against Aedes albopictus. Parasitol Res. 2011 Jul;109(1):221-9. PMID: 21212981.

 

Chidambara Murthy KN, Jayaprakasha GK, et al. Citrus limonin and its glucoside inhibit colon adenocarcinoma cell proliferation through apoptosis. J Agric Food Chem. 2011 Mar 23;59(6):2314-23. PMID: 21338095.

 

Balestrieri E, Pizzimenti F, Ferlazzo A, et al. Antiviral activity of seed extract from Citrus bergamia towards human retroviruses. Bioorg Med Chem. 2011 Mar 15;19(6):2084-9. PMID: 21334901.

 

Kim W, Fan YY, Smith R, et al. Dietary curcumin and limonin suppress CD4+ T-cell proliferation and interleukin-2 production in mice. J Nutr. 2009 May;139(5):1042-8. PMID: 19321585.

" Not dangerous goods.

LKT T0153 Tanshinone I 10 mg 95.1 Diterpene found in Salvia. "1,6-Dimethylphenanthro(1,2-b)furan-10,11-dione 

" Tanshinone A 568-73-0 ≥95% 276.29 C18H12O3 CC1=CC=CC2=C1C=CC3=C2C(=O)C(=O)C4=C3OC=C4C Ambient 4°C Soluble in DMSO. "Park JH, Park OK, Cho JH, et al. Anti-inflammatory Effect of Tanshinone I in Neuroprotection Against Cerebral Ischemia-Reperfusion Injury in the Gerbil Hippocampus. Neurochem Res. 2014 Apr 24. [Epub ahead of print]. PMID: 24760430.

 

Zhou S, Chen W, Su H, et al. Protective properties of tanshinone I against oxidative DNA damage and cytotoxicity. Food Chem Toxicol. 2013 Dec;62:407-12. PMID: 24021569.

 

Tung YT, Chen HL, Lee CY, et al. Active Component of Danshen (Salvia miltiorrhiza Bunge), Tanshinone I, Attenuates Lung Tumorigenesis via Inhibitions of VEGF, Cyclin A, and Cyclin B Expressions. Evid Based Complement Alternat Med. 2013;2013:319247. PMID: 23662128. 

 

Tao S, Zheng Y, Lau A, et al. Tanshinone I activates the Nrf2-dependent antioxidant response and protects against As(III)-induced lung inflammation in vitro and in vivo. Antioxid Redox Signal. 2013 Nov 10;19(14):1647-61. PMID: 23394605.

 

Li Y, Gong Y, Li L, et al. Bioactive tanshinone I inhibits the growth of lung cancer in part via downregulation of Aurora A function. Mol Carcinog. 2013 Jul;52(7):535-43. PMID: 22389266.

 

Li W, Li J, Ashok M, et al. A cardiovascular drug rescues mice from lethal sepsis by selectively attentuating a late-acting proinflammatory mediator, high mobility group box 1. J Immunol. 2007 Mar 15;178(6):3856-3864. PMID: 17339485.

 

Zhang Y, Won SH, Jiang C, et al. Tanshinones fmor Chinese medicinal herb Danshen (Salvia miltiorrhiza Bunge) suppress prostate cancer growth and androgen receptor signaling. Pharm Res. 2012 Jun;29(6):1595-1608. PMID: 22281759." None Not dangerous goods.

LKT T0153 Tanshinone I 25 mg 203.8 Diterpene found in Salvia. "1,6-Dimethylphenanthro(1,2-b)furan-10,11-dione 

" Tanshinone A 568-73-0 ≥95% 276.29 C18H12O3 CC1=CC=CC2=C1C=CC3=C2C(=O)C(=O)C4=C3OC=C4C Ambient 4°C Soluble in DMSO. "Park JH, Park OK, Cho JH, et al. Anti-inflammatory Effect of Tanshinone I in Neuroprotection Against Cerebral Ischemia-Reperfusion Injury in the Gerbil Hippocampus. Neurochem Res. 2014 Apr 24. [Epub ahead of print]. PMID: 24760430.

 

Zhou S, Chen W, Su H, et al. Protective properties of tanshinone I against oxidative DNA damage and cytotoxicity. Food Chem Toxicol. 2013 Dec;62:407-12. PMID: 24021569.

 

Tung YT, Chen HL, Lee CY, et al. Active Component of Danshen (Salvia miltiorrhiza Bunge), Tanshinone I, Attenuates Lung Tumorigenesis via Inhibitions of VEGF, Cyclin A, and Cyclin B Expressions. Evid Based Complement Alternat Med. 2013;2013:319247. PMID: 23662128. 

 

Tao S, Zheng Y, Lau A, et al. Tanshinone I activates the Nrf2-dependent antioxidant response and protects against As(III)-induced lung inflammation in vitro and in vivo. Antioxid Redox Signal. 2013 Nov 10;19(14):1647-61. PMID: 23394605.

 

Li Y, Gong Y, Li L, et al. Bioactive tanshinone I inhibits the growth of lung cancer in part via downregulation of Aurora A function. Mol Carcinog. 2013 Jul;52(7):535-43. PMID: 22389266.

 

Li W, Li J, Ashok M, et al. A cardiovascular drug rescues mice from lethal sepsis by selectively attentuating a late-acting proinflammatory mediator, high mobility group box 1. J Immunol. 2007 Mar 15;178(6):3856-3864. PMID: 17339485.

 

Zhang Y, Won SH, Jiang C, et al. Tanshinones fmor Chinese medicinal herb Danshen (Salvia miltiorrhiza Bunge) suppress prostate cancer growth and androgen receptor signaling. Pharm Res. 2012 Jun;29(6):1595-1608. PMID: 22281759." None Not dangerous goods.

LKT T0153 Tanshinone I 100 mg 652.3 Diterpene found in Salvia. "1,6-Dimethylphenanthro(1,2-b)furan-10,11-dione 

" Tanshinone A 568-73-0 ≥95% 276.29 C18H12O3 CC1=CC=CC2=C1C=CC3=C2C(=O)C(=O)C4=C3OC=C4C Ambient 4°C Soluble in DMSO. "Park JH, Park OK, Cho JH, et al. Anti-inflammatory Effect of Tanshinone I in Neuroprotection Against Cerebral Ischemia-Reperfusion Injury in the Gerbil Hippocampus. Neurochem Res. 2014 Apr 24. [Epub ahead of print]. PMID: 24760430.

 

Zhou S, Chen W, Su H, et al. Protective properties of tanshinone I against oxidative DNA damage and cytotoxicity. Food Chem Toxicol. 2013 Dec;62:407-12. PMID: 24021569.

 

Tung YT, Chen HL, Lee CY, et al. Active Component of Danshen (Salvia miltiorrhiza Bunge), Tanshinone I, Attenuates Lung Tumorigenesis via Inhibitions of VEGF, Cyclin A, and Cyclin B Expressions. Evid Based Complement Alternat Med. 2013;2013:319247. PMID: 23662128. 

 

Tao S, Zheng Y, Lau A, et al. Tanshinone I activates the Nrf2-dependent antioxidant response and protects against As(III)-induced lung inflammation in vitro and in vivo. Antioxid Redox Signal. 2013 Nov 10;19(14):1647-61. PMID: 23394605.

 

Li Y, Gong Y, Li L, et al. Bioactive tanshinone I inhibits the growth of lung cancer in part via downregulation of Aurora A function. Mol Carcinog. 2013 Jul;52(7):535-43. PMID: 22389266.

 

Li W, Li J, Ashok M, et al. A cardiovascular drug rescues mice from lethal sepsis by selectively attentuating a late-acting proinflammatory mediator, high mobility group box 1. J Immunol. 2007 Mar 15;178(6):3856-3864. PMID: 17339485.

 

Zhang Y, Won SH, Jiang C, et al. Tanshinones fmor Chinese medicinal herb Danshen (Salvia miltiorrhiza Bunge) suppress prostate cancer growth and androgen receptor signaling. Pharm Res. 2012 Jun;29(6):1595-1608. PMID: 22281759." None Not dangerous goods.

LKT L3551 Limonin Glucoside 1 mg 144.1 Furanolactone found in Citrus. "Limonin 17 β-D-glucopyranoside

" 123564-61-4 ≥95% 650.67 C32H42O14 CC1(C2CC(=O)C3(C(C24COC(=O)CC4O1)CCC(C35C(O5)C(=O)O)(C)C(c6ccoc6)OC7C(C(C(C(O7)CO)O)O)O)C)C Ambient 4°C Soluble in methanol. "Mahmoud MF, Gamal S, El-Fayoumi HM. Limonin attenuates hepatocellular injury following liver ischemia and reperfusion in rats via toll-like receptor dependent pathway. Eur J Pharmacol. 2014 Jun 23. [Epub ahead of print]. PMID: 24967531.

 

Hafeez F, Akram W, Shaalan EA. Mosquito larvicidal activity of citrus limonoids against Aedes albopictus. Parasitol Res. 2011 Jul;109(1):221-9. PMID: 21212981.

 

Chidambara Murthy KN, Jayaprakasha GK, et al. Citrus limonin and its glucoside inhibit colon adenocarcinoma cell proliferation through apoptosis. J Agric Food Chem. 2011 Mar 23;59(6):2314-23. PMID: 21338095.

 

Balestrieri E, Pizzimenti F, Ferlazzo A, et al. Antiviral activity of seed extract from Citrus bergamia towards human retroviruses. Bioorg Med Chem. 2011 Mar 15;19(6):2084-9. PMID: 21334901.

 

Kim W, Fan YY, Smith R, et al. Dietary curcumin and limonin suppress CD4+ T-cell proliferation and interleukin-2 production in mice. J Nutr. 2009 May;139(5):1042-8. PMID: 19321585.

" Not dangerous goods.

LKT L3551 Limonin Glucoside 5 mg 504.8 Furanolactone found in Citrus. "Limonin 17 β-D-glucopyranoside

" 123564-61-4 ≥95% 650.67 C32H42O14 CC1(C2CC(=O)C3(C(C24COC(=O)CC4O1)CCC(C35C(O5)C(=O)O)(C)C(c6ccoc6)OC7C(C(C(C(O7)CO)O)O)O)C)C Ambient 4°C Soluble in methanol. "Mahmoud MF, Gamal S, El-Fayoumi HM. Limonin attenuates hepatocellular injury following liver ischemia and reperfusion in rats via toll-like receptor dependent pathway. Eur J Pharmacol. 2014 Jun 23. [Epub ahead of print]. PMID: 24967531.

 

Hafeez F, Akram W, Shaalan EA. Mosquito larvicidal activity of citrus limonoids against Aedes albopictus. Parasitol Res. 2011 Jul;109(1):221-9. PMID: 21212981.

 

Chidambara Murthy KN, Jayaprakasha GK, et al. Citrus limonin and its glucoside inhibit colon adenocarcinoma cell proliferation through apoptosis. J Agric Food Chem. 2011 Mar 23;59(6):2314-23. PMID: 21338095.

 

Balestrieri E, Pizzimenti F, Ferlazzo A, et al. Antiviral activity of seed extract from Citrus bergamia towards human retroviruses. Bioorg Med Chem. 2011 Mar 15;19(6):2084-9. PMID: 21334901.

 

Kim W, Fan YY, Smith R, et al. Dietary curcumin and limonin suppress CD4+ T-cell proliferation and interleukin-2 production in mice. J Nutr. 2009 May;139(5):1042-8. PMID: 19321585.

" Not dangerous goods.

LKT T0152 Tandutinib 1 mg 80.4 FLT3, PDGFR, c-Kit inhibitor. 387867-13-2 ≥98% 562.7 C31H42N6O4 CC(C)OC1=CC=C(C=C1)NC(=O)N2CCN(CC2)C3=NC=NC4=CC(=C(C=C43)OC)OCCCN5CCCCC5 Ambient Ambient "Ponnurangam S, Standing D, Rangarajan P, et al. Tandutinib inhibits the Akt/mTOR signaling pathway to inhibit colon cancer growth. Mol Cancer Ther. 2013 May;12(5):598-609. PMID: 23427297.

 

Ohshima-Hosoyama S, Davare MA, Prajapati SI, et al. Preclinical testing of tandutinib in a transgenic medulloblastoma mouse model. J Pediatr Hematol Oncol. 2012 Mar;34(2):116-21. PMID: 22146535.

 

Griswold IJ, Shen LJ, La Rosée P, et al. Effects of MLN518, a dual FLT3 and KIT inhibitor, on normal and malignant hematopoiesis. Blood. 2004 Nov 1;104(9):2912-8. PMID: 15242881.

" Not dangerous goods.

LKT T0152 Tandutinib 5 mg 381.8 FLT3, PDGFR, c-Kit inhibitor. 387867-13-2 ≥98% 562.7 C31H42N6O4 CC(C)OC1=CC=C(C=C1)NC(=O)N2CCN(CC2)C3=NC=NC4=CC(=C(C=C43)OC)OCCCN5CCCCC5 Ambient Ambient "Ponnurangam S, Standing D, Rangarajan P, et al. Tandutinib inhibits the Akt/mTOR signaling pathway to inhibit colon cancer growth. Mol Cancer Ther. 2013 May;12(5):598-609. PMID: 23427297.

 

Ohshima-Hosoyama S, Davare MA, Prajapati SI, et al. Preclinical testing of tandutinib in a transgenic medulloblastoma mouse model. J Pediatr Hematol Oncol. 2012 Mar;34(2):116-21. PMID: 22146535.

 

Griswold IJ, Shen LJ, La Rosée P, et al. Effects of MLN518, a dual FLT3 and KIT inhibitor, on normal and malignant hematopoiesis. Blood. 2004 Nov 1;104(9):2912-8. PMID: 15242881.

" Not dangerous goods.

LKT T0152 Tandutinib 25 mg 924.1 FLT3, PDGFR, c-Kit inhibitor. 387867-13-2 ≥98% 562.7 C31H42N6O4 CC(C)OC1=CC=C(C=C1)NC(=O)N2CCN(CC2)C3=NC=NC4=CC(=C(C=C43)OC)OCCCN5CCCCC5 Ambient Ambient "Ponnurangam S, Standing D, Rangarajan P, et al. Tandutinib inhibits the Akt/mTOR signaling pathway to inhibit colon cancer growth. Mol Cancer Ther. 2013 May;12(5):598-609. PMID: 23427297.

 

Ohshima-Hosoyama S, Davare MA, Prajapati SI, et al. Preclinical testing of tandutinib in a transgenic medulloblastoma mouse model. J Pediatr Hematol Oncol. 2012 Mar;34(2):116-21. PMID: 22146535.

 

Griswold IJ, Shen LJ, La Rosée P, et al. Effects of MLN518, a dual FLT3 and KIT inhibitor, on normal and malignant hematopoiesis. Blood. 2004 Nov 1;104(9):2912-8. PMID: 15242881.

" Not dangerous goods.

LKT L3561 D,L-α-Lipoic Acid 1 g 28.8 Endogenous organosulfur also found in meat and vegetables, required for aerobic metabolism. 1,2-Dithiolane-3-pentanoic acid D,L-Thioctic acid 1077-28-7 ≥98% 206.33 C8H14O2S2 C1CSSC1CCCCC(=O)O Ambient 4°C Insoluble in water. Soluble in fat solvents.  "Shay KP, Moreau RF, Smith EJ, et al. Alpha-lipoic acid as a dietary supplement: molecular mechanisms and therapeutic potential. Biochim Biophys Acta. 2009 Oct;1790(10):1149-60. PMID: 19664690.

 

Petersen Shay K, Moreau RF, et al. Is alpha-lipoic acid a scavenger of reactive oxygen species in vivo? Evidence for its initiation of stress signaling pathways that promote endogenous antioxidant capacity. IUBMB Life. 2008 Jun;60(6):362-7. PMID: 18409172.

" Xn Not dangerous goods.

LKT L3561 D,L-α-Lipoic Acid 5 g 72.4 Endogenous organosulfur also found in meat and vegetables, required for aerobic metabolism. 1,2-Dithiolane-3-pentanoic acid D,L-Thioctic acid 1077-28-7 ≥98% 206.33 C8H14O2S2 C1CSSC1CCCCC(=O)O Ambient 4°C Insoluble in water. Soluble in fat solvents.  "Shay KP, Moreau RF, Smith EJ, et al. Alpha-lipoic acid as a dietary supplement: molecular mechanisms and therapeutic potential. Biochim Biophys Acta. 2009 Oct;1790(10):1149-60. PMID: 19664690.

 

Petersen Shay K, Moreau RF, et al. Is alpha-lipoic acid a scavenger of reactive oxygen species in vivo? Evidence for its initiation of stress signaling pathways that promote endogenous antioxidant capacity. IUBMB Life. 2008 Jun;60(6):362-7. PMID: 18409172.

" Xn Not dangerous goods.

LKT L3561 D,L-α-Lipoic Acid 25 g 142.4 Endogenous organosulfur also found in meat and vegetables, required for aerobic metabolism. 1,2-Dithiolane-3-pentanoic acid D,L-Thioctic acid 1077-28-7 ≥98% 206.33 C8H14O2S2 C1CSSC1CCCCC(=O)O Ambient 4°C Insoluble in water. Soluble in fat solvents.  "Shay KP, Moreau RF, Smith EJ, et al. Alpha-lipoic acid as a dietary supplement: molecular mechanisms and therapeutic potential. Biochim Biophys Acta. 2009 Oct;1790(10):1149-60. PMID: 19664690.

 

Petersen Shay K, Moreau RF, et al. Is alpha-lipoic acid a scavenger of reactive oxygen species in vivo? Evidence for its initiation of stress signaling pathways that promote endogenous antioxidant capacity. IUBMB Life. 2008 Jun;60(6):362-7. PMID: 18409172.

" Xn Not dangerous goods.

LKT L3577 Litorin 1 mg 72.1 Bombesin-like peptide found in amphibians. Ranatesin, 2-de-L-valine-3-de-L-proline- 55749-97-8 ≥95% 1085.28 C51H68N14O11S CC(C)C(C(=O)NCC(=O)NC(CC1=CN=CN1)C(=O)NC(CC2=CC=CC=C2)C(=O)NC(CCSC)C(=O)N)NC(=O)C(C)NC(=O)C(CC3=CNC4=CC=CC=C43)NC(=O)C(CCC(=O)N)NC(=O)C5CCC(=O)N5 Ambient -20°C "

Cline MA, Cofield SA, Tachibana T. Central litorin injection is associated with primary anorexigenic effects that coincide with activation of the magnocellular division of the paraventricular nucleus. Neuropeptides. 2010 Jun;44(3):247-52. PMID: 20116849.

 

Rouissi N, Rhaleb NE, Nantel F, et al. Characterization of bombesin receptors in peripheral contractile organs. Br J Pharmacol. 1991 May;103(1):1141-7. PMID: 1652341.

 

Esakov AI, Ashmarin IP, Serova ON, et al. Litorin and litorin-albumin conjugate as effective regulators of body temperature in rats. Biomed Sci. 1990;1(6):610-2. PMID: 2132946.

 

Mitsuma T, Nogimori T, Sun DH, et al. Litorin (bombesin family) inhibits thyrotropin secretion in rats. Exp Clin Endocrinol. 1986 Jul;87(2):162-8. PMID: 3093255.

 

Falconieri Erspamer G, Mazzanti G, Farruggia G, et al. Parallel bioassay of litorin and phyllolitorins on smooth muscle preparations. Peptides. 1984 Jul-Aug;5(4):765-8. PMID: 6494026.

 

Modlin IM, Lamers CB, Walsh JH. Stimulation of canine pancreatic polypeptide, gastrin, and gastric acid secretion by ranatensin, litorin, bombesin nonapeptide and substance P. Regul Pept. 1981 Jan;1(4):279-88. PMID: 6166964.

" Not dangerous goods.

LKT L3577 Litorin 2 mg 123.1 Bombesin-like peptide found in amphibians. Ranatesin, 2-de-L-valine-3-de-L-proline- 55749-97-8 ≥95% 1085.28 C51H68N14O11S CC(C)C(C(=O)NCC(=O)NC(CC1=CN=CN1)C(=O)NC(CC2=CC=CC=C2)C(=O)NC(CCSC)C(=O)N)NC(=O)C(C)NC(=O)C(CC3=CNC4=CC=CC=C43)NC(=O)C(CCC(=O)N)NC(=O)C5CCC(=O)N5 Ambient -20°C "

Cline MA, Cofield SA, Tachibana T. Central litorin injection is associated with primary anorexigenic effects that coincide with activation of the magnocellular division of the paraventricular nucleus. Neuropeptides. 2010 Jun;44(3):247-52. PMID: 20116849.

 

Rouissi N, Rhaleb NE, Nantel F, et al. Characterization of bombesin receptors in peripheral contractile organs. Br J Pharmacol. 1991 May;103(1):1141-7. PMID: 1652341.

 

Esakov AI, Ashmarin IP, Serova ON, et al. Litorin and litorin-albumin conjugate as effective regulators of body temperature in rats. Biomed Sci. 1990;1(6):610-2. PMID: 2132946.

 

Mitsuma T, Nogimori T, Sun DH, et al. Litorin (bombesin family) inhibits thyrotropin secretion in rats. Exp Clin Endocrinol. 1986 Jul;87(2):162-8. PMID: 3093255.

 

Falconieri Erspamer G, Mazzanti G, Farruggia G, et al. Parallel bioassay of litorin and phyllolitorins on smooth muscle preparations. Peptides. 1984 Jul-Aug;5(4):765-8. PMID: 6494026.

 

Modlin IM, Lamers CB, Walsh JH. Stimulation of canine pancreatic polypeptide, gastrin, and gastric acid secretion by ranatensin, litorin, bombesin nonapeptide and substance P. Regul Pept. 1981 Jan;1(4):279-88. PMID: 6166964.

" Not dangerous goods.

LKT L3577 Litorin 5 mg 216.1 Bombesin-like peptide found in amphibians. Ranatesin, 2-de-L-valine-3-de-L-proline- 55749-97-8 ≥95% 1085.28 C51H68N14O11S CC(C)C(C(=O)NCC(=O)NC(CC1=CN=CN1)C(=O)NC(CC2=CC=CC=C2)C(=O)NC(CCSC)C(=O)N)NC(=O)C(C)NC(=O)C(CC3=CNC4=CC=CC=C43)NC(=O)C(CCC(=O)N)NC(=O)C5CCC(=O)N5 Ambient -20°C "

Cline MA, Cofield SA, Tachibana T. Central litorin injection is associated with primary anorexigenic effects that coincide with activation of the magnocellular division of the paraventricular nucleus. Neuropeptides. 2010 Jun;44(3):247-52. PMID: 20116849.

 

Rouissi N, Rhaleb NE, Nantel F, et al. Characterization of bombesin receptors in peripheral contractile organs. Br J Pharmacol. 1991 May;103(1):1141-7. PMID: 1652341.

 

Esakov AI, Ashmarin IP, Serova ON, et al. Litorin and litorin-albumin conjugate as effective regulators of body temperature in rats. Biomed Sci. 1990;1(6):610-2. PMID: 2132946.

 

Mitsuma T, Nogimori T, Sun DH, et al. Litorin (bombesin family) inhibits thyrotropin secretion in rats. Exp Clin Endocrinol. 1986 Jul;87(2):162-8. PMID: 3093255.

 

Falconieri Erspamer G, Mazzanti G, Farruggia G, et al. Parallel bioassay of litorin and phyllolitorins on smooth muscle preparations. Peptides. 1984 Jul-Aug;5(4):765-8. PMID: 6494026.

 

Modlin IM, Lamers CB, Walsh JH. Stimulation of canine pancreatic polypeptide, gastrin, and gastric acid secretion by ranatensin, litorin, bombesin nonapeptide and substance P. Regul Pept. 1981 Jan;1(4):279-88. PMID: 6166964.

" Not dangerous goods.

LKT L5648 Lomustine 500 mg 339.8 Nitrosourea, DNA alkylator. N-(2-Chloroethyl)-N'-cyclohexyl-N-nitrosourea Belustine; Cecenu' CeeNU; CiNU 13010-47-4 ≥98% 233.7 C9H16ClN3O2 C1CCC(CC1)NC(=O)N(CCCl)N=O Light sensitive. Ambient 4°C Soluble in ethanol or chloroform or acetone. "Buccheri G, Ferrigno D, Rosso A. A phase II study of methotrexate, doxorubicin, cyclophosphamide, and lomustine chemotherapy and lonidamine in advanced non-small cell lung cancer. Cancer. 1993 Sep 1;72(5):1564-72. PMID: 8394198.

 

Kamiya S. Synthesis of antitumor nitrosourea derivatives and chemical studies of their mechanism of action. Eisei Shikenjo Hokoku. 1986;(104):1-19. PMID: 3471287.

" T "UN number: 2811 Class:  6.1  Packing group:  III

Proper shipping name:  Toxic solids, organic, n.o.s. (Lomustine)

Marine pollutant:  No, Poison inhalation hazard:  No"

LKT L5648 Lomustine 100 mg 88.3 Nitrosourea, DNA alkylator. N-(2-Chloroethyl)-N'-cyclohexyl-N-nitrosourea Belustine; Cecenu' CeeNU; CiNU 13010-47-4 ≥98% 233.7 C9H16ClN3O2 C1CCC(CC1)NC(=O)N(CCCl)N=O Light sensitive. Ambient 4°C Soluble in ethanol or chloroform or acetone. "Buccheri G, Ferrigno D, Rosso A. A phase II study of methotrexate, doxorubicin, cyclophosphamide, and lomustine chemotherapy and lonidamine in advanced non-small cell lung cancer. Cancer. 1993 Sep 1;72(5):1564-72. PMID: 8394198.

 

Kamiya S. Synthesis of antitumor nitrosourea derivatives and chemical studies of their mechanism of action. Eisei Shikenjo Hokoku. 1986;(104):1-19. PMID: 3471287.

" T "UN number: 2811 Class:  6.1  Packing group:  III

Proper shipping name:  Toxic solids, organic, n.o.s. (Lomustine)

Marine pollutant:  No, Poison inhalation hazard:  No"

LKT L5648 Lomustine 50 mg 54.4 Nitrosourea, DNA alkylator. N-(2-Chloroethyl)-N'-cyclohexyl-N-nitrosourea Belustine; Cecenu' CeeNU; CiNU 13010-47-4 ≥98% 233.7 C9H16ClN3O2 C1CCC(CC1)NC(=O)N(CCCl)N=O Light sensitive. Ambient 4°C Soluble in ethanol or chloroform or acetone. "Buccheri G, Ferrigno D, Rosso A. A phase II study of methotrexate, doxorubicin, cyclophosphamide, and lomustine chemotherapy and lonidamine in advanced non-small cell lung cancer. Cancer. 1993 Sep 1;72(5):1564-72. PMID: 8394198.

 

Kamiya S. Synthesis of antitumor nitrosourea derivatives and chemical studies of their mechanism of action. Eisei Shikenjo Hokoku. 1986;(104):1-19. PMID: 3471287.

" T "UN number: 2811 Class:  6.1  Packing group:  III

Proper shipping name:  Toxic solids, organic, n.o.s. (Lomustine)

Marine pollutant:  No, Poison inhalation hazard:  No"

LKT T0119 Taxol Side Chain β-lactam 5 mg 242 Taxol synthesis intermediate. (3R,4S)-3-(acetyloxy)-2-oxo-4-phenyl-1-azetidinecarboxylic acid 1,1-dimethylethyl ester 161183-22-8 ≥98% 305.33 C16H19NO5 CC(=O)OC1C(N(C1=O)C(=O)OC(C)(C)C)C2=CC=CC=C2 Ambient -20°C Not dangerous goods.

LKT T0119 Taxol Side Chain β-lactam 10 mg 420.9 Taxol synthesis intermediate. (3R,4S)-3-(acetyloxy)-2-oxo-4-phenyl-1-azetidinecarboxylic acid 1,1-dimethylethyl ester 161183-22-8 ≥98% 305.33 C16H19NO5 CC(=O)OC1C(N(C1=O)C(=O)OC(C)(C)C)C2=CC=CC=C2 Ambient -20°C Not dangerous goods.

LKT T0119 Taxol Side Chain β-lactam 25 mg 842 Taxol synthesis intermediate. (3R,4S)-3-(acetyloxy)-2-oxo-4-phenyl-1-azetidinecarboxylic acid 1,1-dimethylethyl ester 161183-22-8 ≥98% 305.33 C16H19NO5 CC(=O)OC1C(N(C1=O)C(=O)OC(C)(C)C)C2=CC=CC=C2 Ambient -20°C Not dangerous goods.

LKT L5658 Lonidamine 5 mg 75.2 Hexokinase inhibitor, aerobic glycolysis inhibitor. "1-(2,4-Dichlorobenzyl)-1H-indazole-3-carboxylic acid 

" Diclondazolic acid; DICA; AF-1890; Doridamina. 50264-69-2 ≥98% 321.16 C15H10Cl2N2O2 C1=CC=C2C(=C1)C(=NN2CC3=C(C=C(C=C3)Cl)Cl)C(=O)O Ambient Ambient Soluble in methanol or acetic acid. "Schmeisser S, Zarse K, Ristow M. Lonidamine extends lifespan of adult Caenorhabditis elegans by increasing the formation of mitochondrial reactive oxygen species. Horm Metab Res. 2011 Sep;43(10):687-92. PMID: 21932172.

 

Chambers JW, Fowler ML, Morris MT, et al. The anti-trypanosomal agent lonidamine inhibits Trypanosoma brucei hexokinase 1. Mol Biochem Parasitol. 2008 Apr;158(2):202-7. PMID: 18262292.

 

Traina ME, Guarino M, Natoli A, et al. Lonidamine affects testicular steroid hormones in immature mice. Toxicol Appl Pharmacol. 2007 May 15;221(1):95-101. PMID: 17442358.

 

Ditonno P, Battaglia M, Selvaggio O, et al. Clinical Evidence Supporting the Role of Lonidamine for the Treatment of BPH. Rev Urol. 2005;7 Suppl 7:S27-33. PMID: 16986058.

" T Not dangerous goods.

LKT L5658 Lonidamine 25 mg 134.9 Hexokinase inhibitor, aerobic glycolysis inhibitor. "1-(2,4-Dichlorobenzyl)-1H-indazole-3-carboxylic acid 

" Diclondazolic acid; DICA; AF-1890; Doridamina. 50264-69-2 ≥98% 321.16 C15H10Cl2N2O2 C1=CC=C2C(=C1)C(=NN2CC3=C(C=C(C=C3)Cl)Cl)C(=O)O Ambient Ambient Soluble in methanol or acetic acid. "Schmeisser S, Zarse K, Ristow M. Lonidamine extends lifespan of adult Caenorhabditis elegans by increasing the formation of mitochondrial reactive oxygen species. Horm Metab Res. 2011 Sep;43(10):687-92. PMID: 21932172.

 

Chambers JW, Fowler ML, Morris MT, et al. The anti-trypanosomal agent lonidamine inhibits Trypanosoma brucei hexokinase 1. Mol Biochem Parasitol. 2008 Apr;158(2):202-7. PMID: 18262292.

 

Traina ME, Guarino M, Natoli A, et al. Lonidamine affects testicular steroid hormones in immature mice. Toxicol Appl Pharmacol. 2007 May 15;221(1):95-101. PMID: 17442358.

 

Ditonno P, Battaglia M, Selvaggio O, et al. Clinical Evidence Supporting the Role of Lonidamine for the Treatment of BPH. Rev Urol. 2005;7 Suppl 7:S27-33. PMID: 16986058.

" T Not dangerous goods.

LKT L5658 Lonidamine 100 mg 539.7 Hexokinase inhibitor, aerobic glycolysis inhibitor. "1-(2,4-Dichlorobenzyl)-1H-indazole-3-carboxylic acid 

" Diclondazolic acid; DICA; AF-1890; Doridamina. 50264-69-2 ≥98% 321.16 C15H10Cl2N2O2 C1=CC=C2C(=C1)C(=NN2CC3=C(C=C(C=C3)Cl)Cl)C(=O)O Ambient Ambient Soluble in methanol or acetic acid. "Schmeisser S, Zarse K, Ristow M. Lonidamine extends lifespan of adult Caenorhabditis elegans by increasing the formation of mitochondrial reactive oxygen species. Horm Metab Res. 2011 Sep;43(10):687-92. PMID: 21932172.

 

Chambers JW, Fowler ML, Morris MT, et al. The anti-trypanosomal agent lonidamine inhibits Trypanosoma brucei hexokinase 1. Mol Biochem Parasitol. 2008 Apr;158(2):202-7. PMID: 18262292.

 

Traina ME, Guarino M, Natoli A, et al. Lonidamine affects testicular steroid hormones in immature mice. Toxicol Appl Pharmacol. 2007 May 15;221(1):95-101. PMID: 17442358.

 

Ditonno P, Battaglia M, Selvaggio O, et al. Clinical Evidence Supporting the Role of Lonidamine for the Treatment of BPH. Rev Urol. 2005;7 Suppl 7:S27-33. PMID: 16986058.

" T Not dangerous goods.

LKT T0118 7-Epi-cephalomannine 5 mg 647 Cephalomannine derivative found in Taxus; potential DNA polymerase inhibitor and microtubule depolymerization inhibitor. ≥95% 831.9 C45H53NO14 CC=C(C)C(=O)NC(C1=CC=CC=C1)C(C(=O)OC2CC3(C(C4C(C(CC5C4(CO5)OC(=O)C)O)(C(=O)C(C(=C2C)C3(C)C)OC(=O)C)C)OC(=O)C6=CC=CC=C6)O)O Ambient -20°C "Li Y, Qin F, Wang SM, et al. Chemical studies on Taxus canadensis. Chem Biodivers. 2013 Oct;10(10):1729-53. PMID: 24130020.

 

Oshige M, Takenouchi M, Kato Y, et al. Taxol derivatives are selective inhibitors of DNA polymerase alpha. Bioorg Med Chem. 2004 May 15;12(10):2597-601. PMID: 15110841.

 

Pandey RC, Yankov LK, Poulev A, et al. Synthesis and separation of potential anticancer active dihalocephalomannine diastereomers from extracts of Taxus yunnanensis. J Nat Prod. 1998 Jan;61(1):57-63. PMID: 9461653.

" Not dangerous goods.

LKT T0118 7-Epi-cephalomannine 10 mg 1109 Cephalomannine derivative found in Taxus; potential DNA polymerase inhibitor and microtubule depolymerization inhibitor. ≥95% 831.9 C45H53NO14 CC=C(C)C(=O)NC(C1=CC=CC=C1)C(C(=O)OC2CC3(C(C4C(C(CC5C4(CO5)OC(=O)C)O)(C(=O)C(C(=C2C)C3(C)C)OC(=O)C)C)OC(=O)C6=CC=CC=C6)O)O Ambient -20°C "Li Y, Qin F, Wang SM, et al. Chemical studies on Taxus canadensis. Chem Biodivers. 2013 Oct;10(10):1729-53. PMID: 24130020.

 

Oshige M, Takenouchi M, Kato Y, et al. Taxol derivatives are selective inhibitors of DNA polymerase alpha. Bioorg Med Chem. 2004 May 15;12(10):2597-601. PMID: 15110841.

 

Pandey RC, Yankov LK, Poulev A, et al. Synthesis and separation of potential anticancer active dihalocephalomannine diastereomers from extracts of Taxus yunnanensis. J Nat Prod. 1998 Jan;61(1):57-63. PMID: 9461653.

" Not dangerous goods.

LKT T0118 7-Epi-cephalomannine 25 mg 1848 Cephalomannine derivative found in Taxus; potential DNA polymerase inhibitor and microtubule depolymerization inhibitor. ≥95% 831.9 C45H53NO14 CC=C(C)C(=O)NC(C1=CC=CC=C1)C(C(=O)OC2CC3(C(C4C(C(CC5C4(CO5)OC(=O)C)O)(C(=O)C(C(=C2C)C3(C)C)OC(=O)C)C)OC(=O)C6=CC=CC=C6)O)O Ambient -20°C "Li Y, Qin F, Wang SM, et al. Chemical studies on Taxus canadensis. Chem Biodivers. 2013 Oct;10(10):1729-53. PMID: 24130020.

 

Oshige M, Takenouchi M, Kato Y, et al. Taxol derivatives are selective inhibitors of DNA polymerase alpha. Bioorg Med Chem. 2004 May 15;12(10):2597-601. PMID: 15110841.

 

Pandey RC, Yankov LK, Poulev A, et al. Synthesis and separation of potential anticancer active dihalocephalomannine diastereomers from extracts of Taxus yunnanensis. J Nat Prod. 1998 Jan;61(1):57-63. PMID: 9461653.

" Not dangerous goods.

LKT L5660 Loperamide Hydrochloride 5 g 61.1 FIASMA, μOR agonist, potential HCN channel blocker. 4-(4-Chlorophenyl)-4-hydroxy-N,N-dimethyl-α,α- diphenyl-1-piperidinbutanamide hydrochloride Imodium; Tebloc; Dissenten; Lopemin 34552-83-5 ≥98% 513.51 C29H33ClN2O2 HCl CN(C)C(=O)C(CCN1CCC(CC1)(C2=CC=C(C=C2)Cl)O)(C3=CC=CC=C3)C4=CC=CC=C4.Cl Ambient Ambient Soluble in methanol or chloroform. "Kumar R. Loperamide: from antidiarrheal to analgesic. J Opioid Manag. 2013 Jul-Aug;9(4):301-2. PMID: 24353024.

 

Kumar R, Reeta KH, Ray SB. Antinociceptive effect of intrathecal loperamide: role of mu-opioid receptor and calcium channels. Eur J Pharmacol. 2012 Dec 5;696(1-3):77-82. PMID: 23022331.

 

Placidi E, Marciani L, Hoad CL, et al. The effects of loperamide, or loperamide plus simethicone, on the distribution of gut water as assessed by MRI in a mannitol model of secretory diarrhoea. Aliment Pharmacol Ther. 2012 Jul;36(1):64-73. PMID: 22582872.

 

Chumakova YA, Bashkatova VG, Sudakov SK. Changes in feeding behavior after peripheral loperamide administration in rats. Bull Exp Biol Med. 2011 Feb;150(4):398-400. PMID: 22268026.

" T "UN Number: 2811     Class: 6.1       Packing Group: III

Proper shipping name: Toxic solids, organic, n.o.s. (Loperamide hydrochloride) 

Marine pollutant: No  Poison Inhalation Hazard: No"

LKT T0117 Benzyl Analog of Taxol 1 mg 462.1 Benzyl taxol analog; potential microtubule depolymerization inhibitor. 173101-56-9 ≥95% 867.93 C48H53NO14 CC1=C2C(C(=O)C3(C(CC4C(C3C(C(C2(C)C)(CC1OC(=O)C(C(C5=CC=CC=C5)NC(=O)CC6=CC=CC=C6)O)O)OC(=O)C7=CC=CC=C7)(CO4)OC(=O)C)O)C)OC(=O)C Ambient -20°C "Li Y, Qin F, Wang SM, et al. Chemical studies on Taxus canadensis. Chem Biodivers. 2013 Oct;10(10):1729-53. PMID: 24130020.

 

Orr GA, Verdier-Pinard P, McDaid H, et al. Mechanisms of Taxol resistance related to microtubules. Oncogene. 2003 Oct 20;22(47):7280-95. PMID: 14576838.

 

Jordan MA. Mechanism of action of antitumor drugs that interact with microtubules and tubulin. Curr Med Chem Anticancer Agents. 2002 Jan;2(1):1-17. PMID: 12678749.

" Not dangerous goods.

LKT L5660 Loperamide Hydrochloride 25 g 251.5 FIASMA, μOR agonist, potential HCN channel blocker. 4-(4-Chlorophenyl)-4-hydroxy-N,N-dimethyl-α,α- diphenyl-1-piperidinbutanamide hydrochloride Imodium; Tebloc; Dissenten; Lopemin 34552-83-5 ≥98% 513.51 C29H33ClN2O2 HCl CN(C)C(=O)C(CCN1CCC(CC1)(C2=CC=C(C=C2)Cl)O)(C3=CC=CC=C3)C4=CC=CC=C4.Cl Ambient Ambient Soluble in methanol or chloroform. "Kumar R. Loperamide: from antidiarrheal to analgesic. J Opioid Manag. 2013 Jul-Aug;9(4):301-2. PMID: 24353024.

 

Kumar R, Reeta KH, Ray SB. Antinociceptive effect of intrathecal loperamide: role of mu-opioid receptor and calcium channels. Eur J Pharmacol. 2012 Dec 5;696(1-3):77-82. PMID: 23022331.

 

Placidi E, Marciani L, Hoad CL, et al. The effects of loperamide, or loperamide plus simethicone, on the distribution of gut water as assessed by MRI in a mannitol model of secretory diarrhoea. Aliment Pharmacol Ther. 2012 Jul;36(1):64-73. PMID: 22582872.

 

Chumakova YA, Bashkatova VG, Sudakov SK. Changes in feeding behavior after peripheral loperamide administration in rats. Bull Exp Biol Med. 2011 Feb;150(4):398-400. PMID: 22268026.

" T "UN Number: 2811     Class: 6.1       Packing Group: III

Proper shipping name: Toxic solids, organic, n.o.s. (Loperamide hydrochloride) 

Marine pollutant: No  Poison Inhalation Hazard: No"

LKT T0117 Benzyl Analog of Taxol 5 mg 1571.1 Benzyl taxol analog; potential microtubule depolymerization inhibitor. 173101-56-9 ≥95% 867.93 C48H53NO14 CC1=C2C(C(=O)C3(C(CC4C(C3C(C(C2(C)C)(CC1OC(=O)C(C(C5=CC=CC=C5)NC(=O)CC6=CC=CC=C6)O)O)OC(=O)C7=CC=CC=C7)(CO4)OC(=O)C)O)C)OC(=O)C Ambient -20°C "Li Y, Qin F, Wang SM, et al. Chemical studies on Taxus canadensis. Chem Biodivers. 2013 Oct;10(10):1729-53. PMID: 24130020.

 

Orr GA, Verdier-Pinard P, McDaid H, et al. Mechanisms of Taxol resistance related to microtubules. Oncogene. 2003 Oct 20;22(47):7280-95. PMID: 14576838.

 

Jordan MA. Mechanism of action of antitumor drugs that interact with microtubules and tubulin. Curr Med Chem Anticancer Agents. 2002 Jan;2(1):1-17. PMID: 12678749.

" Not dangerous goods.

LKT L5749 Lomefloxacin Hydrochloride 1 g 39 Fluoroquinolone; topoisomerase IV and bacterial DNA gyrase inhibitor. "1-Ethyl-6,8-difluoro-1,4-dihydro-7-(3-methyl-1-

piperazinyl)-4-oxo-3-quinolinecarboxylic acid monohydrochloride" Lomefloxacin monohydrochloride; Bareon; Chimono; Lomebact; Maxaquin; Okacyn; Uniquin 98079-52-8 ≥98% 387.81 C17H19F2N3O3 HCl CCN1C=C(C(=O)C2=CC(=C(C(=C21)F)N3CCNC(C3)C)F)C(=O)O.Cl Ambient Ambient "Martínez L, Chignell CF. Photocleavage of DNA by the fluoroquinolone antibacterials. J Photochem Photobiol B. 1998 Aug 21;45(1):51-9. PMID: 9819899.

 

Just PM. Overview of the fluoroquinolone antibiotics. Pharmacotherapy. 1993 Mar-Apr;13(2 Pt 2):4S-17S. PMID: 8386356.

 

Symonds WT, Nix DE. Lomefloxacin and temafloxacin: two new fluoroquinolone antimicrobials. Clin Pharm. 1992 Sep;11(9):753-66. PMID: 1325892.

" Xn Not dangerous goods.

LKT L5749 Lomefloxacin Hydrochloride 5 g 138.1 Fluoroquinolone; topoisomerase IV and bacterial DNA gyrase inhibitor. "1-Ethyl-6,8-difluoro-1,4-dihydro-7-(3-methyl-1-

piperazinyl)-4-oxo-3-quinolinecarboxylic acid monohydrochloride" Lomefloxacin monohydrochloride; Bareon; Chimono; Lomebact; Maxaquin; Okacyn; Uniquin 98079-52-8 ≥98% 387.81 C17H19F2N3O3 HCl CCN1C=C(C(=O)C2=CC(=C(C(=C21)F)N3CCNC(C3)C)F)C(=O)O.Cl Ambient Ambient "Martínez L, Chignell CF. Photocleavage of DNA by the fluoroquinolone antibacterials. J Photochem Photobiol B. 1998 Aug 21;45(1):51-9. PMID: 9819899.

 

Just PM. Overview of the fluoroquinolone antibiotics. Pharmacotherapy. 1993 Mar-Apr;13(2 Pt 2):4S-17S. PMID: 8386356.

 

Symonds WT, Nix DE. Lomefloxacin and temafloxacin: two new fluoroquinolone antimicrobials. Clin Pharm. 1992 Sep;11(9):753-66. PMID: 1325892.

" Xn Not dangerous goods.

LKT L5749 Lomefloxacin Hydrochloride 10 g 216.4 Fluoroquinolone; topoisomerase IV and bacterial DNA gyrase inhibitor. "1-Ethyl-6,8-difluoro-1,4-dihydro-7-(3-methyl-1-

piperazinyl)-4-oxo-3-quinolinecarboxylic acid monohydrochloride" Lomefloxacin monohydrochloride; Bareon; Chimono; Lomebact; Maxaquin; Okacyn; Uniquin 98079-52-8 ≥98% 387.81 C17H19F2N3O3 HCl CCN1C=C(C(=O)C2=CC(=C(C(=C21)F)N3CCNC(C3)C)F)C(=O)O.Cl Ambient Ambient "Martínez L, Chignell CF. Photocleavage of DNA by the fluoroquinolone antibacterials. J Photochem Photobiol B. 1998 Aug 21;45(1):51-9. PMID: 9819899.

 

Just PM. Overview of the fluoroquinolone antibiotics. Pharmacotherapy. 1993 Mar-Apr;13(2 Pt 2):4S-17S. PMID: 8386356.

 

Symonds WT, Nix DE. Lomefloxacin and temafloxacin: two new fluoroquinolone antimicrobials. Clin Pharm. 1992 Sep;11(9):753-66. PMID: 1325892.

" Xn Not dangerous goods.

LKT T0116 2",3"-Dihydrocephalomannine 5 mg 647 Cephalomannine derivative found in Taxus; potential DNA polymerase inhibitor and microtubule depolymerization inhibitor. ≥90% 833.92 C45H55NO14 Ambient -20°C "Li Y, Qin F, Wang SM, et al. Chemical studies on Taxus canadensis. Chem Biodivers. 2013 Oct;10(10):1729-53. PMID: 24130020.

 

Oshige M, Takenouchi M, Kato Y, et al. Taxol derivatives are selective inhibitors of DNA polymerase alpha. Bioorg Med Chem. 2004 May 15;12(10):2597-601. PMID: 15110841.

 

Pandey RC, Yankov LK, Poulev A, et al. Synthesis and separation of potential anticancer active dihalocephalomannine diastereomers from extracts of Taxus yunnanensis. J Nat Prod. 1998 Jan;61(1):57-63. PMID: 9461653.

" Not dangerous goods.

LKT T0116 2",3"-Dihydrocephalomannine 10 mg 1109 Cephalomannine derivative found in Taxus; potential DNA polymerase inhibitor and microtubule depolymerization inhibitor. ≥90% 833.92 C45H55NO14 Ambient -20°C "Li Y, Qin F, Wang SM, et al. Chemical studies on Taxus canadensis. Chem Biodivers. 2013 Oct;10(10):1729-53. PMID: 24130020.

 

Oshige M, Takenouchi M, Kato Y, et al. Taxol derivatives are selective inhibitors of DNA polymerase alpha. Bioorg Med Chem. 2004 May 15;12(10):2597-601. PMID: 15110841.

 

Pandey RC, Yankov LK, Poulev A, et al. Synthesis and separation of potential anticancer active dihalocephalomannine diastereomers from extracts of Taxus yunnanensis. J Nat Prod. 1998 Jan;61(1):57-63. PMID: 9461653.

" Not dangerous goods.

LKT T0116 2",3"-Dihydrocephalomannine 25 mg 1847.2 Cephalomannine derivative found in Taxus; potential DNA polymerase inhibitor and microtubule depolymerization inhibitor. ≥90% 833.92 C45H55NO14 Ambient -20°C "Li Y, Qin F, Wang SM, et al. Chemical studies on Taxus canadensis. Chem Biodivers. 2013 Oct;10(10):1729-53. PMID: 24130020.

 

Oshige M, Takenouchi M, Kato Y, et al. Taxol derivatives are selective inhibitors of DNA polymerase alpha. Bioorg Med Chem. 2004 May 15;12(10):2597-601. PMID: 15110841.

 

Pandey RC, Yankov LK, Poulev A, et al. Synthesis and separation of potential anticancer active dihalocephalomannine diastereomers from extracts of Taxus yunnanensis. J Nat Prod. 1998 Jan;61(1):57-63. PMID: 9461653.

" Not dangerous goods.

LKT T0115 Taxol Side Chain Acid 5 mg 284.6 Side chain commonly attached to taxanes. ≥98% 285.29 C16H15NO4 Ambient -20°C "Li Y, Qin F, Wang SM, et al. Chemical studies on Taxus canadensis. Chem Biodivers. 2013 Oct;10(10):1729-53. PMID: 24130020.

 

Ha HJ, Park GS, Ahn YG, et al. Practical synthesis of Taxol side chain. Bioorg Med Chem Lett. 1998 Jul 7;8(13):1619-22. PMID: 9873401.

 

Swindell CS, Krauss NE, Horwitz SB, et al. Biologically active taxol analogues with deleted A-ring side chain substituents and variable C-2' configurations. J Med Chem. 1991 Mar;34(3):1176-84. PMID: 1672157.

" Not dangerous goods.

LKT T0115 Taxol Side Chain Acid 10 mg 495 Side chain commonly attached to taxanes. ≥98% 285.29 C16H15NO4 Ambient -20°C "Li Y, Qin F, Wang SM, et al. Chemical studies on Taxus canadensis. Chem Biodivers. 2013 Oct;10(10):1729-53. PMID: 24130020.

 

Ha HJ, Park GS, Ahn YG, et al. Practical synthesis of Taxol side chain. Bioorg Med Chem Lett. 1998 Jul 7;8(13):1619-22. PMID: 9873401.

 

Swindell CS, Krauss NE, Horwitz SB, et al. Biologically active taxol analogues with deleted A-ring side chain substituents and variable C-2' configurations. J Med Chem. 1991 Mar;34(3):1176-84. PMID: 1672157.

" Not dangerous goods.

LKT L5750 Lomeguatrib 10 mg 67.9 MGMT inhibitor. 192441-08-0  ≥98% 326.17 C10H8BrN5OS C1=C(SC=C1Br)COC2=NC(=NC3=C2NC=N3)N Ambient Ambient "Taspinar M, Ilgaz S, Ozdemir M, et al. Effect of lomeguatrib-temozolomide combination on MGMT promoter methylation and expression in primary glioblastoma tumor cells. Tumour Biol. 2013 Jun;34(3):1935-47. PMID: 23519841.

 

Tawbi HA, Villaruz L, Tarhini A, et al. Inhibition of DNA repair with MGMT pseudosubstrates: phase I study of lomeguatrib in combination with dacarbazine in patients with advanced melanoma and other solid tumours. Br J Cancer. 2011 Sep 6;105(6):773-7. PMID: 21811257.

 

Watson AJ, Sabharwal A, Thorncroft M, et al. Tumor O(6)-methylguanine-DNA methyltransferase inactivation by oral lomeguatrib. Clin Cancer Res. 2010 Jan 15;16(2):743-9. PMID: 20068091.

 

Watson AJ, Middleton MR, McGown G, et al. O(6)-methylguanine-DNA methyltransferase depletion and DNA damage in patients with melanoma treated with temozolomide alone or with lomeguatrib. Br J Cancer. 2009 Apr 21;100(8):1250-6. PMID: 19367283.

 

Khan O, Middleton MR. The therapeutic potential of O6-alkylguanine DNA alkyltransferase inhibitors. Expert Opin Investig Drugs. 2007 Oct;16(10):1573-84. PMID: 17922622.

" Not dangerous goods.

LKT L5750 Lomeguatrib 25 mg 136 MGMT inhibitor. 192441-08-0  ≥98% 326.17 C10H8BrN5OS C1=C(SC=C1Br)COC2=NC(=NC3=C2NC=N3)N Ambient Ambient "Taspinar M, Ilgaz S, Ozdemir M, et al. Effect of lomeguatrib-temozolomide combination on MGMT promoter methylation and expression in primary glioblastoma tumor cells. Tumour Biol. 2013 Jun;34(3):1935-47. PMID: 23519841.

 

Tawbi HA, Villaruz L, Tarhini A, et al. Inhibition of DNA repair with MGMT pseudosubstrates: phase I study of lomeguatrib in combination with dacarbazine in patients with advanced melanoma and other solid tumours. Br J Cancer. 2011 Sep 6;105(6):773-7. PMID: 21811257.

 

Watson AJ, Sabharwal A, Thorncroft M, et al. Tumor O(6)-methylguanine-DNA methyltransferase inactivation by oral lomeguatrib. Clin Cancer Res. 2010 Jan 15;16(2):743-9. PMID: 20068091.

 

Watson AJ, Middleton MR, McGown G, et al. O(6)-methylguanine-DNA methyltransferase depletion and DNA damage in patients with melanoma treated with temozolomide alone or with lomeguatrib. Br J Cancer. 2009 Apr 21;100(8):1250-6. PMID: 19367283.

 

Khan O, Middleton MR. The therapeutic potential of O6-alkylguanine DNA alkyltransferase inhibitors. Expert Opin Investig Drugs. 2007 Oct;16(10):1573-84. PMID: 17922622.

" Not dangerous goods.

LKT T0115 Taxol Side Chain Acid 25 mg 990.2 Side chain commonly attached to taxanes. ≥98% 285.29 C16H15NO4 Ambient -20°C "Li Y, Qin F, Wang SM, et al. Chemical studies on Taxus canadensis. Chem Biodivers. 2013 Oct;10(10):1729-53. PMID: 24130020.

 

Ha HJ, Park GS, Ahn YG, et al. Practical synthesis of Taxol side chain. Bioorg Med Chem Lett. 1998 Jul 7;8(13):1619-22. PMID: 9873401.

 

Swindell CS, Krauss NE, Horwitz SB, et al. Biologically active taxol analogues with deleted A-ring side chain substituents and variable C-2' configurations. J Med Chem. 1991 Mar;34(3):1176-84. PMID: 1672157.

" Not dangerous goods.

LKT L5750 Lomeguatrib 100 mg 434.9 MGMT inhibitor. 192441-08-0  ≥98% 326.17 C10H8BrN5OS C1=C(SC=C1Br)COC2=NC(=NC3=C2NC=N3)N Ambient Ambient "Taspinar M, Ilgaz S, Ozdemir M, et al. Effect of lomeguatrib-temozolomide combination on MGMT promoter methylation and expression in primary glioblastoma tumor cells. Tumour Biol. 2013 Jun;34(3):1935-47. PMID: 23519841.

 

Tawbi HA, Villaruz L, Tarhini A, et al. Inhibition of DNA repair with MGMT pseudosubstrates: phase I study of lomeguatrib in combination with dacarbazine in patients with advanced melanoma and other solid tumours. Br J Cancer. 2011 Sep 6;105(6):773-7. PMID: 21811257.

 

Watson AJ, Sabharwal A, Thorncroft M, et al. Tumor O(6)-methylguanine-DNA methyltransferase inactivation by oral lomeguatrib. Clin Cancer Res. 2010 Jan 15;16(2):743-9. PMID: 20068091.

 

Watson AJ, Middleton MR, McGown G, et al. O(6)-methylguanine-DNA methyltransferase depletion and DNA damage in patients with melanoma treated with temozolomide alone or with lomeguatrib. Br J Cancer. 2009 Apr 21;100(8):1250-6. PMID: 19367283.

 

Khan O, Middleton MR. The therapeutic potential of O6-alkylguanine DNA alkyltransferase inhibitors. Expert Opin Investig Drugs. 2007 Oct;16(10):1573-84. PMID: 17922622.

" Not dangerous goods.

LKT L5751 Lomerizine Dihydrochloride 500 mg 115.5 L-type and T-type Ca2+ and TRP antagonist. 1-[Bis(4-fluorophenyl)methyl]-4-[(2,3,4-trimethoxyphenyl)methyl]piperazine dihydrochloride Lomerizine dihydrochloride 101477-54-7 ≥98% 541.47 C27H30F2N2O3 2HCl COC1=C(C(=C(C=C1)CN2CCN(CC2)C(C3=CC=C(C=C3)F)C4=CC=C(C=C4)F)OC)OC.Cl.Cl Ambient Ambient "Tran LT, Gentil BJ, Sullivan KE, et al. The voltage-gated calcium channel blocker lomerizine is neuroprotective in motor neurons expressing mutant SOD1, but not TDP-43. J Neurochem. 2014 Apr 9. [Epub ahead of print]. PMID: 24716897.

 

Inoue Y, Yabe T. Lomerizine therapy for the treatment of benign paroxysmal vertigo of childhood transitioning into atypical basilar migraine: A case report. Exp Ther Med. 2013 Jun;5(6):1573-1575. PMID: 23837033.

 

Ito Y, Nakamura S, Tanaka H, et al. Lomerizine, a Ca2+ channel blocker, protects against neuronal degeneration within the visual center of the brain after retinal damage in mice. CNS Neurosci Ther. 2010 Apr;16(2):103-14. PMID: 19788586.

 

Fitzgerald M, Bartlett CA, Harvey AR, Dunlop SA. Early events of secondary degeneration after partial optic nerve transection: an immunohistochemical study. J Neurotrauma. 2010 Feb;27(2):439-452. PMID: 19852581.

" Xn, N "UN number: 3077     Class: 9     Packing Group: III

Proper shipping name: Environmentally hazardous substance, solid, n.o.s. (Lomerizine hydrochloride)"

LKT L5751 Lomerizine Dihydrochloride 1 g 184.8 L-type and T-type Ca2+ and TRP antagonist. 1-[Bis(4-fluorophenyl)methyl]-4-[(2,3,4-trimethoxyphenyl)methyl]piperazine dihydrochloride Lomerizine dihydrochloride 101477-54-7 ≥98% 541.47 C27H30F2N2O3 2HCl COC1=C(C(=C(C=C1)CN2CCN(CC2)C(C3=CC=C(C=C3)F)C4=CC=C(C=C4)F)OC)OC.Cl.Cl Ambient Ambient "Tran LT, Gentil BJ, Sullivan KE, et al. The voltage-gated calcium channel blocker lomerizine is neuroprotective in motor neurons expressing mutant SOD1, but not TDP-43. J Neurochem. 2014 Apr 9. [Epub ahead of print]. PMID: 24716897.

 

Inoue Y, Yabe T. Lomerizine therapy for the treatment of benign paroxysmal vertigo of childhood transitioning into atypical basilar migraine: A case report. Exp Ther Med. 2013 Jun;5(6):1573-1575. PMID: 23837033.

 

Ito Y, Nakamura S, Tanaka H, et al. Lomerizine, a Ca2+ channel blocker, protects against neuronal degeneration within the visual center of the brain after retinal damage in mice. CNS Neurosci Ther. 2010 Apr;16(2):103-14. PMID: 19788586.

 

Fitzgerald M, Bartlett CA, Harvey AR, Dunlop SA. Early events of secondary degeneration after partial optic nerve transection: an immunohistochemical study. J Neurotrauma. 2010 Feb;27(2):439-452. PMID: 19852581.

" Xn, N "UN number: 3077     Class: 9     Packing Group: III

Proper shipping name: Environmentally hazardous substance, solid, n.o.s. (Lomerizine hydrochloride)"

LKT L5751 Lomerizine Dihydrochloride 5 g 797.2 L-type and T-type Ca2+ and TRP antagonist. 1-[Bis(4-fluorophenyl)methyl]-4-[(2,3,4-trimethoxyphenyl)methyl]piperazine dihydrochloride Lomerizine dihydrochloride 101477-54-7 ≥98% 541.47 C27H30F2N2O3 2HCl COC1=C(C(=C(C=C1)CN2CCN(CC2)C(C3=CC=C(C=C3)F)C4=CC=C(C=C4)F)OC)OC.Cl.Cl Ambient Ambient "Tran LT, Gentil BJ, Sullivan KE, et al. The voltage-gated calcium channel blocker lomerizine is neuroprotective in motor neurons expressing mutant SOD1, but not TDP-43. J Neurochem. 2014 Apr 9. [Epub ahead of print]. PMID: 24716897.

 

Inoue Y, Yabe T. Lomerizine therapy for the treatment of benign paroxysmal vertigo of childhood transitioning into atypical basilar migraine: A case report. Exp Ther Med. 2013 Jun;5(6):1573-1575. PMID: 23837033.

 

Ito Y, Nakamura S, Tanaka H, et al. Lomerizine, a Ca2+ channel blocker, protects against neuronal degeneration within the visual center of the brain after retinal damage in mice. CNS Neurosci Ther. 2010 Apr;16(2):103-14. PMID: 19788586.

 

Fitzgerald M, Bartlett CA, Harvey AR, Dunlop SA. Early events of secondary degeneration after partial optic nerve transection: an immunohistochemical study. J Neurotrauma. 2010 Feb;27(2):439-452. PMID: 19852581.

" Xn, N "UN number: 3077     Class: 9     Packing Group: III

Proper shipping name: Environmentally hazardous substance, solid, n.o.s. (Lomerizine hydrochloride)"

LKT L5767 Loratadine 500 mg 57.8 Histamine H1 antagonist, FIASMA. 4-(8-Chloro-5,6-dihydro-11H-benzo[5,6]cyclohepta- [1,2-b]pyridin-11-ylidene)-1-piperidinecarboxylic acid ethyl ester Claritin; Lisino 79794-75-5 ≥98% 382.88 C22H23ClN2O2 CCOC(=O)N1CCC(=C2C3=C(CCC4=C2N=CC=C4)C=C(C=C3)Cl)CC1 Ambient Ambient Soluble in DMSO (26mg/mL). Insoluble in water. "Soule BP, Simone NL, DeGraff WG, et al. Loratadine dysregulates cell cycle progression and enhances the effect of radiation in human tumor cell lines. Radiat Oncol. 2010 Feb 3;5:8. PMID: 20128919.

 

DuBuske LM. Review of desloratadine for the treatment of allergic rhinitis, chronic idiopathic urticaria and allergic inflammatory disorders. Expert Opin Pharmacother. 2005 Nov;6(14):2511-23. PMID: 16259582.

" Xi Not dangerous goods.

LKT L5767 Loratadine 1 g 88 Histamine H1 antagonist, FIASMA. 4-(8-Chloro-5,6-dihydro-11H-benzo[5,6]cyclohepta- [1,2-b]pyridin-11-ylidene)-1-piperidinecarboxylic acid ethyl ester Claritin; Lisino 79794-75-5 ≥98% 382.88 C22H23ClN2O2 CCOC(=O)N1CCC(=C2C3=C(CCC4=C2N=CC=C4)C=C(C=C3)Cl)CC1 Ambient Ambient Soluble in DMSO (26mg/mL). Insoluble in water. "Soule BP, Simone NL, DeGraff WG, et al. Loratadine dysregulates cell cycle progression and enhances the effect of radiation in human tumor cell lines. Radiat Oncol. 2010 Feb 3;5:8. PMID: 20128919.

 

DuBuske LM. Review of desloratadine for the treatment of allergic rhinitis, chronic idiopathic urticaria and allergic inflammatory disorders. Expert Opin Pharmacother. 2005 Nov;6(14):2511-23. PMID: 16259582.

" Xi Not dangerous goods.

LKT L5767 Loratadine 5 g 346.5 Histamine H1 antagonist, FIASMA. 4-(8-Chloro-5,6-dihydro-11H-benzo[5,6]cyclohepta- [1,2-b]pyridin-11-ylidene)-1-piperidinecarboxylic acid ethyl ester Claritin; Lisino 79794-75-5 ≥98% 382.88 C22H23ClN2O2 CCOC(=O)N1CCC(=C2C3=C(CCC4=C2N=CC=C4)C=C(C=C3)Cl)CC1 Ambient Ambient Soluble in DMSO (26mg/mL). Insoluble in water. "Soule BP, Simone NL, DeGraff WG, et al. Loratadine dysregulates cell cycle progression and enhances the effect of radiation in human tumor cell lines. Radiat Oncol. 2010 Feb 3;5:8. PMID: 20128919.

 

DuBuske LM. Review of desloratadine for the treatment of allergic rhinitis, chronic idiopathic urticaria and allergic inflammatory disorders. Expert Opin Pharmacother. 2005 Nov;6(14):2511-23. PMID: 16259582.

" Xi Not dangerous goods.

LKT T0114 Taxinine M 5 mg 495 Taxane found in Taxus; DNA polymerase inhibitor, potential microtubule depolymerization inhibitor. ≥98% 686.7 C35H42NO14 CC(=O)OC1CC(C(=C)C2C1(C(C(C3(C4(COC3(C(=O)CC4C2OC(=O)C)C)C)O)OC(=O)C)OC(=O)C)COC(=O)C5=CC=CC=C5)O Ambient -20°C "Li Y, Qin F, Wang SM, et al. Chemical studies on Taxus canadensis. Chem Biodivers. 2013 Oct;10(10):1729-53. PMID: 24130020.

 

Oshige M, Takenouchi M, Kato Y, et al. Taxol derivatives are selective inhibitors of DNA polymerase alpha. Bioorg Med Chem. 2004 May 15;12(10):2597-601. PMID: 15110841.

 

Prasain JK, Stefanowicz P, Kiyota T, et al. Taxines from the needles of Taxus wallichiana. Phytochemistry. 2001 Dec;58(8):1167-70. PMID: 11738401.

 

Beutler JA, Chmurny GM, Look SA, et al. Taxinine M, a new tetracyclic taxane from Taxus brevifolia. J Nat Prod. 1991 May-Jun;54(3):893-7. PMID: 1955887.

" Not dangerous goods.

LKT T0114 Taxinine M 10 mg 792.3 Taxane found in Taxus; DNA polymerase inhibitor, potential microtubule depolymerization inhibitor. ≥98% 686.7 C35H42NO14 CC(=O)OC1CC(C(=C)C2C1(C(C(C3(C4(COC3(C(=O)CC4C2OC(=O)C)C)C)O)OC(=O)C)OC(=O)C)COC(=O)C5=CC=CC=C5)O Ambient -20°C "Li Y, Qin F, Wang SM, et al. Chemical studies on Taxus canadensis. Chem Biodivers. 2013 Oct;10(10):1729-53. PMID: 24130020.

 

Oshige M, Takenouchi M, Kato Y, et al. Taxol derivatives are selective inhibitors of DNA polymerase alpha. Bioorg Med Chem. 2004 May 15;12(10):2597-601. PMID: 15110841.

 

Prasain JK, Stefanowicz P, Kiyota T, et al. Taxines from the needles of Taxus wallichiana. Phytochemistry. 2001 Dec;58(8):1167-70. PMID: 11738401.

 

Beutler JA, Chmurny GM, Look SA, et al. Taxinine M, a new tetracyclic taxane from Taxus brevifolia. J Nat Prod. 1991 May-Jun;54(3):893-7. PMID: 1955887.

" Not dangerous goods.

LKT T0114 Taxinine M 25 mg 1484.9 Taxane found in Taxus; DNA polymerase inhibitor, potential microtubule depolymerization inhibitor. ≥98% 686.7 C35H42NO14 CC(=O)OC1CC(C(=C)C2C1(C(C(C3(C4(COC3(C(=O)CC4C2OC(=O)C)C)C)O)OC(=O)C)OC(=O)C)COC(=O)C5=CC=CC=C5)O Ambient -20°C "Li Y, Qin F, Wang SM, et al. Chemical studies on Taxus canadensis. Chem Biodivers. 2013 Oct;10(10):1729-53. PMID: 24130020.

 

Oshige M, Takenouchi M, Kato Y, et al. Taxol derivatives are selective inhibitors of DNA polymerase alpha. Bioorg Med Chem. 2004 May 15;12(10):2597-601. PMID: 15110841.

 

Prasain JK, Stefanowicz P, Kiyota T, et al. Taxines from the needles of Taxus wallichiana. Phytochemistry. 2001 Dec;58(8):1167-70. PMID: 11738401.

 

Beutler JA, Chmurny GM, Look SA, et al. Taxinine M, a new tetracyclic taxane from Taxus brevifolia. J Nat Prod. 1991 May-Jun;54(3):893-7. PMID: 1955887.

" Not dangerous goods.

LKT L5769 Lorglumide Sodium 25 mg 149.5 CCK antagonist. (±)-4-[(3,4-Dichlorobenzoyl)amino]-5-(dipentyl- amino)-5-oxopentanoic acid sodium salt Lorglumide sodium salt ≥98% 481.39 C22H31Cl2N2O4Na CCCCCN(CCCCC)C(=O)C(CCC(=O)[O-])NC(=O)C1=CC(=C(C=C1)Cl)Cl.[Na+] Ambient 4°C Soluble in methanol or water. "González-Puga C, García-Navarro A, Escames G, et al. Selective CCK-A but not CCK-B receptor antagonists inhibit HT-29 cell proliferation: synergism with pharmacological levels of melatonin. J Pineal Res. 2005 Oct;39(3):243-50. PMID: 16150104.

 

Makovec F, Bani M, Cereda R, et al. Antispasmodic activity on the gallbladder of the mouse of CR 1409 (lorglumide) a potent antagonist of peripheral CCK. Pharmacol Res Commun. 1987 Jan;19(1):41-51. PMID: 3575382.

 

Makovec F, Bani M, Cereda R, et al. Pharmacological properties of lorglumide as a member of a new class of cholecystokinin antagonists. Arzneimittelforschung. 1987 Nov;37(11):1265-8. PMID: 3440035.

" Not dangerous goods.

LKT L5769 Lorglumide Sodium 100 mg 478.3 CCK antagonist. (±)-4-[(3,4-Dichlorobenzoyl)amino]-5-(dipentyl- amino)-5-oxopentanoic acid sodium salt Lorglumide sodium salt ≥98% 481.39 C22H31Cl2N2O4Na CCCCCN(CCCCC)C(=O)C(CCC(=O)[O-])NC(=O)C1=CC(=C(C=C1)Cl)Cl.[Na+] Ambient 4°C Soluble in methanol or water. "González-Puga C, García-Navarro A, Escames G, et al. Selective CCK-A but not CCK-B receptor antagonists inhibit HT-29 cell proliferation: synergism with pharmacological levels of melatonin. J Pineal Res. 2005 Oct;39(3):243-50. PMID: 16150104.

 

Makovec F, Bani M, Cereda R, et al. Antispasmodic activity on the gallbladder of the mouse of CR 1409 (lorglumide) a potent antagonist of peripheral CCK. Pharmacol Res Commun. 1987 Jan;19(1):41-51. PMID: 3575382.

 

Makovec F, Bani M, Cereda R, et al. Pharmacological properties of lorglumide as a member of a new class of cholecystokinin antagonists. Arzneimittelforschung. 1987 Nov;37(11):1265-8. PMID: 3440035.

" Not dangerous goods.

LKT L5822 Lofexidine Hydrochloride 1 g 76.7 α2-adrenergic agonist. 2-[1-(2,6-Dichlorophenoxy)ethyl]-4,5-dihydro-1H- imidazole hydrochloride Lofetensin; Loxacor 21498-08-8 ≥98% 295.6 C11H12Cl2N2O HCl CC(C1=NCCN1)OC2=C(C=CC=C2Cl)Cl.Cl Ambient 4°C Soluble in water and ethanol. Slightly soluble in 2-propanol. Practically insoluble in ether. "Gowing L, Farrell MF, Ali R, et al. Alpha2-adrenergic agonists for the management of opioid withdrawal. Cochrane Database Syst Rev. 2014 Mar 31;3:CD002024. PMID: 24683051.

 

Lê AD, Harding S, Juzytsch W, et al. Role of alpha-2 adrenoceptors in stress-induced reinstatement of alcohol seeking and alcohol self-administration in rats. Psychopharmacology (Berl). 2005 May;179(2):366-73. PMID: 15551068.

" Not dangerous goods.

LKT L5822 Lofexidine Hydrochloride 5 g 325.5 α2-adrenergic agonist. 2-[1-(2,6-Dichlorophenoxy)ethyl]-4,5-dihydro-1H- imidazole hydrochloride Lofetensin; Loxacor 21498-08-8 ≥98% 295.6 C11H12Cl2N2O HCl CC(C1=NCCN1)OC2=C(C=CC=C2Cl)Cl.Cl Ambient 4°C Soluble in water and ethanol. Slightly soluble in 2-propanol. Practically insoluble in ether. "Gowing L, Farrell MF, Ali R, et al. Alpha2-adrenergic agonists for the management of opioid withdrawal. Cochrane Database Syst Rev. 2014 Mar 31;3:CD002024. PMID: 24683051.

 

Lê AD, Harding S, Juzytsch W, et al. Role of alpha-2 adrenoceptors in stress-induced reinstatement of alcohol seeking and alcohol self-administration in rats. Psychopharmacology (Berl). 2005 May;179(2):366-73. PMID: 15551068.

" Not dangerous goods.

LKT T0109 13-Acetyl-9-dihydrobaccatin-III 5 mg 369.8 Found in Taxus, starting material for synthesis of taxol. 142203-65-4 ≥98% 630.68 C33H44O12 CC1=C2C(C(C3(C(CC4C(C3C(C(C2(C)C)(CC1OC(=O)C)O)OC(=O)C5=CC=CC=C5)(CO4)OC(=O)C)O)C)O)OC(=O)C Ambient -20°C "Li Y, Qin F, Wang SM, et al. Chemical studies on Taxus canadensis. Chem Biodivers. 2013 Oct;10(10):1729-53. PMID: 24130020.

 

Ketchum RE, Tandon M, Gibson DM, et al. Isolation of labeled 9-dihydrobaccatin III and related taxoids from cell cultures of taxuscell cultures of taxus canadensis elicited with m. J Nat Prod. 1999 Oct;62(10):1395-8. PMID: 10543900.

" Not dangerous goods.

LKT L5822 Lofexidine Hydrochloride 25 g 1155 α2-adrenergic agonist. 2-[1-(2,6-Dichlorophenoxy)ethyl]-4,5-dihydro-1H- imidazole hydrochloride Lofetensin; Loxacor 21498-08-8 ≥98% 295.6 C11H12Cl2N2O HCl CC(C1=NCCN1)OC2=C(C=CC=C2Cl)Cl.Cl Ambient 4°C Soluble in water and ethanol. Slightly soluble in 2-propanol. Practically insoluble in ether. "Gowing L, Farrell MF, Ali R, et al. Alpha2-adrenergic agonists for the management of opioid withdrawal. Cochrane Database Syst Rev. 2014 Mar 31;3:CD002024. PMID: 24683051.

 

Lê AD, Harding S, Juzytsch W, et al. Role of alpha-2 adrenoceptors in stress-induced reinstatement of alcohol seeking and alcohol self-administration in rats. Psychopharmacology (Berl). 2005 May;179(2):366-73. PMID: 15551068.

" Not dangerous goods.

LKT T0109 13-Acetyl-9-dihydrobaccatin-III 10 mg 591.4 Found in Taxus, starting material for synthesis of taxol. 142203-65-4 ≥98% 630.68 C33H44O12 CC1=C2C(C(C3(C(CC4C(C3C(C(C2(C)C)(CC1OC(=O)C)O)OC(=O)C5=CC=CC=C5)(CO4)OC(=O)C)O)C)O)OC(=O)C Ambient -20°C "Li Y, Qin F, Wang SM, et al. Chemical studies on Taxus canadensis. Chem Biodivers. 2013 Oct;10(10):1729-53. PMID: 24130020.

 

Ketchum RE, Tandon M, Gibson DM, et al. Isolation of labeled 9-dihydrobaccatin III and related taxoids from cell cultures of taxuscell cultures of taxus canadensis elicited with m. J Nat Prod. 1999 Oct;62(10):1395-8. PMID: 10543900.

" Not dangerous goods.

LKT T0109 13-Acetyl-9-dihydrobaccatin-III 25 mg 1155.2 Found in Taxus, starting material for synthesis of taxol. 142203-65-4 ≥98% 630.68 C33H44O12 CC1=C2C(C(C3(C(CC4C(C3C(C(C2(C)C)(CC1OC(=O)C)O)OC(=O)C5=CC=CC=C5)(CO4)OC(=O)C)O)C)O)OC(=O)C Ambient -20°C "Li Y, Qin F, Wang SM, et al. Chemical studies on Taxus canadensis. Chem Biodivers. 2013 Oct;10(10):1729-53. PMID: 24130020.

 

Ketchum RE, Tandon M, Gibson DM, et al. Isolation of labeled 9-dihydrobaccatin III and related taxoids from cell cultures of taxuscell cultures of taxus canadensis elicited with m. J Nat Prod. 1999 Oct;62(10):1395-8. PMID: 10543900.

" Not dangerous goods.

LKT L5870 Lornoxicam 100 mg 75 NSAID; COX-1/2 inhibitor. 70374-39-9    ≥98% 371.82 C13H10ClN3O4S2 CN1C(=C(C2=C(S1(=O)=O)C=C(S2)Cl)O)C(=O)NC3=CC=CC=N3 Ambient Ambient "Topcu I, Vatansever S, Bayram E, et al. The effects of lornoxicam on neuroprotection following diffuse traumatic brain injury in rats. Turk Neurosurg. 2013;23(6):764-71. PMID: 24310460.

 

Yin J, Huang Z, Xia Y, et al. Lornoxicam suppresses recurrent herpetic stromal keratitis through down-regulation of nuclear factor-kappaB: an experimental study in mice. Mol Vis. 2009 Jun 14;15:1252-9. PMID: 19547717.

 

Futaki N, Harada M, Sugimoto M, et al. The importance of brain PGE2 inhibition versus paw PGE2 inhibition as a mechanism for the separation of analgesic and antipyretic effects of lornoxicam in rats with paw inflammation. J Pharm Pharmacol. 2009 May;61(5):607-14. PMID: 19405999.

 

Radhofer-Welte S, Rabasseda X. Lornoxicam, a new potent NSAID with an improved tolerability profile. Drugs Today (Barc). 2000 Jan;36(1):55-76. PMID: 12879104.

" Xi "UN number: 2811     Class: 6.1     Packing Group: II

Proper shipping name: Toxic solid, organic, n.o.s. (Lornoxicam)"

LKT L5870 Lornoxicam 250 mg 168.7 NSAID; COX-1/2 inhibitor. 70374-39-9    ≥98% 371.82 C13H10ClN3O4S2 CN1C(=C(C2=C(S1(=O)=O)C=C(S2)Cl)O)C(=O)NC3=CC=CC=N3 Ambient Ambient "Topcu I, Vatansever S, Bayram E, et al. The effects of lornoxicam on neuroprotection following diffuse traumatic brain injury in rats. Turk Neurosurg. 2013;23(6):764-71. PMID: 24310460.

 

Yin J, Huang Z, Xia Y, et al. Lornoxicam suppresses recurrent herpetic stromal keratitis through down-regulation of nuclear factor-kappaB: an experimental study in mice. Mol Vis. 2009 Jun 14;15:1252-9. PMID: 19547717.

 

Futaki N, Harada M, Sugimoto M, et al. The importance of brain PGE2 inhibition versus paw PGE2 inhibition as a mechanism for the separation of analgesic and antipyretic effects of lornoxicam in rats with paw inflammation. J Pharm Pharmacol. 2009 May;61(5):607-14. PMID: 19405999.

 

Radhofer-Welte S, Rabasseda X. Lornoxicam, a new potent NSAID with an improved tolerability profile. Drugs Today (Barc). 2000 Jan;36(1):55-76. PMID: 12879104.

" Xi "UN number: 2811     Class: 6.1     Packing Group: II

Proper shipping name: Toxic solid, organic, n.o.s. (Lornoxicam)"

LKT L5870 Lornoxicam 1 g 515.7 NSAID; COX-1/2 inhibitor. 70374-39-9    ≥98% 371.82 C13H10ClN3O4S2 CN1C(=C(C2=C(S1(=O)=O)C=C(S2)Cl)O)C(=O)NC3=CC=CC=N3 Ambient Ambient "Topcu I, Vatansever S, Bayram E, et al. The effects of lornoxicam on neuroprotection following diffuse traumatic brain injury in rats. Turk Neurosurg. 2013;23(6):764-71. PMID: 24310460.

 

Yin J, Huang Z, Xia Y, et al. Lornoxicam suppresses recurrent herpetic stromal keratitis through down-regulation of nuclear factor-kappaB: an experimental study in mice. Mol Vis. 2009 Jun 14;15:1252-9. PMID: 19547717.

 

Futaki N, Harada M, Sugimoto M, et al. The importance of brain PGE2 inhibition versus paw PGE2 inhibition as a mechanism for the separation of analgesic and antipyretic effects of lornoxicam in rats with paw inflammation. J Pharm Pharmacol. 2009 May;61(5):607-14. PMID: 19405999.

 

Radhofer-Welte S, Rabasseda X. Lornoxicam, a new potent NSAID with an improved tolerability profile. Drugs Today (Barc). 2000 Jan;36(1):55-76. PMID: 12879104.

" Xi "UN number: 2811     Class: 6.1     Packing Group: II

Proper shipping name: Toxic solid, organic, n.o.s. (Lornoxicam)"

LKT L5993 Loxoprofen Sodium Dihydrate 100 mg 84.3 NSAID; COX-1/2 inhibitor. a-Methyl-4-[(2-oxocyclopentyl)methyl]benzeneacetic sodium salt dihydrate 226721-96-6 ≥98% 304.31 C15H17NaO3 2H2O CC(C1=CC=C(C=C1)CC2CCCC2=O)C(=O)[O-].O.O.[Na+] Ambient Ambient Chloroform, Methanol, Water "Shin HI, Kim BH, Chang HS, et al. Long-term effect of loxoprofen sodium on nocturia in patients with benign prostatic hyperplasia. Korean J Urol. 2011 Apr;52(4):265-8. PMID: 21556213.

 

Hamaguchi M, Seno T, Yamamoto A, et al. Loxoprofen Sodium, a Non-Selective NSAID, Reduces Atherosclerosis in Mice by Reducing Inflammation. J Clin Biochem Nutr. 2010 Sep;47(2):138-47. PMID: 20838569.

 

Araki T, Yokoyama T, Araki M, et al. A clinical investigation of the mechanism of loxoprofen, a non-steroidal anti-inflammatory drug, for patients with nocturia. Acta Med Okayama. 2008 Dec;62(6):373-8. PMID: 19122682.

 

Tsuruoka M, Maeda M, Hayashi B, et al. NSAID loxoprofen inhibits high threshold or wide dynamic range neuronal responses in the rat at different time-courses. Pharmacol Rep. 2008 Mar-Apr;60(2):156-62. PMID: 18443376.

 

Sugimoto M, Kojima T, Asami M, et al. Inhibition of prostaglandin production in the inflammatory tissue by loxoprofen-Na, an anti-inflammatory prodrug. Biochem Pharmacol. 1991 Nov 27;42(12):2363-8. PMID: 1764120.

" Not dangerous goods.

LKT L5993 Loxoprofen Sodium Dihydrate 250 mg 140.7 NSAID; COX-1/2 inhibitor. a-Methyl-4-[(2-oxocyclopentyl)methyl]benzeneacetic sodium salt dihydrate 226721-96-6 ≥98% 304.31 C15H17NaO3 2H2O CC(C1=CC=C(C=C1)CC2CCCC2=O)C(=O)[O-].O.O.[Na+] Ambient Ambient Chloroform, Methanol, Water "Shin HI, Kim BH, Chang HS, et al. Long-term effect of loxoprofen sodium on nocturia in patients with benign prostatic hyperplasia. Korean J Urol. 2011 Apr;52(4):265-8. PMID: 21556213.

 

Hamaguchi M, Seno T, Yamamoto A, et al. Loxoprofen Sodium, a Non-Selective NSAID, Reduces Atherosclerosis in Mice by Reducing Inflammation. J Clin Biochem Nutr. 2010 Sep;47(2):138-47. PMID: 20838569.

 

Araki T, Yokoyama T, Araki M, et al. A clinical investigation of the mechanism of loxoprofen, a non-steroidal anti-inflammatory drug, for patients with nocturia. Acta Med Okayama. 2008 Dec;62(6):373-8. PMID: 19122682.

 

Tsuruoka M, Maeda M, Hayashi B, et al. NSAID loxoprofen inhibits high threshold or wide dynamic range neuronal responses in the rat at different time-courses. Pharmacol Rep. 2008 Mar-Apr;60(2):156-62. PMID: 18443376.

 

Sugimoto M, Kojima T, Asami M, et al. Inhibition of prostaglandin production in the inflammatory tissue by loxoprofen-Na, an anti-inflammatory prodrug. Biochem Pharmacol. 1991 Nov 27;42(12):2363-8. PMID: 1764120.

" Not dangerous goods.

LKT L5993 Loxoprofen Sodium Dihydrate 1 g 281.2 NSAID; COX-1/2 inhibitor. a-Methyl-4-[(2-oxocyclopentyl)methyl]benzeneacetic sodium salt dihydrate 226721-96-6 ≥98% 304.31 C15H17NaO3 2H2O CC(C1=CC=C(C=C1)CC2CCCC2=O)C(=O)[O-].O.O.[Na+] Ambient Ambient Chloroform, Methanol, Water "Shin HI, Kim BH, Chang HS, et al. Long-term effect of loxoprofen sodium on nocturia in patients with benign prostatic hyperplasia. Korean J Urol. 2011 Apr;52(4):265-8. PMID: 21556213.

 

Hamaguchi M, Seno T, Yamamoto A, et al. Loxoprofen Sodium, a Non-Selective NSAID, Reduces Atherosclerosis in Mice by Reducing Inflammation. J Clin Biochem Nutr. 2010 Sep;47(2):138-47. PMID: 20838569.

 

Araki T, Yokoyama T, Araki M, et al. A clinical investigation of the mechanism of loxoprofen, a non-steroidal anti-inflammatory drug, for patients with nocturia. Acta Med Okayama. 2008 Dec;62(6):373-8. PMID: 19122682.

 

Tsuruoka M, Maeda M, Hayashi B, et al. NSAID loxoprofen inhibits high threshold or wide dynamic range neuronal responses in the rat at different time-courses. Pharmacol Rep. 2008 Mar-Apr;60(2):156-62. PMID: 18443376.

 

Sugimoto M, Kojima T, Asami M, et al. Inhibition of prostaglandin production in the inflammatory tissue by loxoprofen-Na, an anti-inflammatory prodrug. Biochem Pharmacol. 1991 Nov 27;42(12):2363-8. PMID: 1764120.

" Not dangerous goods.

LKT L8248 Lumiracoxib 100 mg 121.9 NSAID; COX-2 inhibitor. 2-[(2-Chloro-6-fluorophenyl)amino]-5-methylbenzeneacetic acid 220991-20-8 ≥98% 293.72 C15H13ClFNO2 CC1=CC(=C(C=C1)NC2=C(C=CC=C2Cl)F)CC(=O)O Ambient Ambient "Windsor MA, Valk PL, Xu S, et al. Exploring the molecular determinants of substrate-selective inhibition of cyclooxygenase-2 by lumiracoxib. Bioorg Med Chem Lett. 2013 Nov 1;23(21):5860-4. PMID: 24060487.

 

Renna NF, Diez ER, Lembo C, et al. Role of Cox-2 in vascular inflammation: an experimental model of metabolic syndrome. Mediators Inflamm. 2013;2013:513251. PMID: 23476105.

 

Hao JQ, Li Q, Xu SP, et al. Effect of lumiracoxib on proliferation and apoptosis of human nonsmall cell lung cancer cells in vitro. Chin Med J (Engl). 2008 Apr 5;121(7):602-7. PMID: 18466679.

 

Selg E, Buccellati C, Andersson M, et al. Antagonism of thromboxane receptors by diclofenac and lumiracoxib. Br J Pharmacol. 2007 Dec;152(8):1185-95. Erratum in: Br J Pharmacol. 2008 Apr;153(8):1763. Ambrosio, E [corrected to Ambrosio, M]. PMID: 17965743.

 

Ni J, Shu YY, Zhu YN, et al. COX-2 inhibitors ameliorate experimental autoimmune encephalomyelitis through modulating IFN-gamma and IL-10 production by inhibiting T-bet expression. J Neuroimmunol. 2007 May;186(1-2):94-103. PMID: 17442406.

 

Esser R, Berry C, Du Z, et al. Preclinical pharmacology of lumiracoxib: a novel selective inhibitor of cyclooxygenase-2. Br J Pharmacol. 2005 Feb;144(4):538-50. PMID: 15655513.

" Not dangerous goods.

LKT L8248 Lumiracoxib 250 mg 234.5 NSAID; COX-2 inhibitor. 2-[(2-Chloro-6-fluorophenyl)amino]-5-methylbenzeneacetic acid 220991-20-8 ≥98% 293.72 C15H13ClFNO2 CC1=CC(=C(C=C1)NC2=C(C=CC=C2Cl)F)CC(=O)O Ambient Ambient "Windsor MA, Valk PL, Xu S, et al. Exploring the molecular determinants of substrate-selective inhibition of cyclooxygenase-2 by lumiracoxib. Bioorg Med Chem Lett. 2013 Nov 1;23(21):5860-4. PMID: 24060487.

 

Renna NF, Diez ER, Lembo C, et al. Role of Cox-2 in vascular inflammation: an experimental model of metabolic syndrome. Mediators Inflamm. 2013;2013:513251. PMID: 23476105.

 

Hao JQ, Li Q, Xu SP, et al. Effect of lumiracoxib on proliferation and apoptosis of human nonsmall cell lung cancer cells in vitro. Chin Med J (Engl). 2008 Apr 5;121(7):602-7. PMID: 18466679.

 

Selg E, Buccellati C, Andersson M, et al. Antagonism of thromboxane receptors by diclofenac and lumiracoxib. Br J Pharmacol. 2007 Dec;152(8):1185-95. Erratum in: Br J Pharmacol. 2008 Apr;153(8):1763. Ambrosio, E [corrected to Ambrosio, M]. PMID: 17965743.

 

Ni J, Shu YY, Zhu YN, et al. COX-2 inhibitors ameliorate experimental autoimmune encephalomyelitis through modulating IFN-gamma and IL-10 production by inhibiting T-bet expression. J Neuroimmunol. 2007 May;186(1-2):94-103. PMID: 17442406.

 

Esser R, Berry C, Du Z, et al. Preclinical pharmacology of lumiracoxib: a novel selective inhibitor of cyclooxygenase-2. Br J Pharmacol. 2005 Feb;144(4):538-50. PMID: 15655513.

" Not dangerous goods.

LKT T0108 10-Deacetyl-7-xylosyltaxol 5 mg 461 Taxane found in species of Taxus; potential microtubule depolymerization inhibitor. "10-Deacetyl-7-xylosyl paclitaxel,

10-Deacetylpaclitaxel 7-xyloside,

10-Deacetyltaxol 7-xyloside" 90332-63-1 ≥90% 943.98 C50H57NO17 Ambient -20°C "Hanson RL, Wasylyk JM, Nanduri VB, et al. Site-specific enzymatic hydrolysis of taxanes at C-10 and C-13. J Biol Chem. 1994 Sep 2;269(35):22145-9. PMID: 7915279.

 

Slichenmyer WJ, Von Hoff DD. New natural products in cancer chemotherapy. J Clin Pharmacol. 1990 Sep;30(9):770-88. PMID: 1980498.

" Not dangerous goods.

LKT L8248 Lumiracoxib 1 g 712.6 NSAID; COX-2 inhibitor. 2-[(2-Chloro-6-fluorophenyl)amino]-5-methylbenzeneacetic acid 220991-20-8 ≥98% 293.72 C15H13ClFNO2 CC1=CC(=C(C=C1)NC2=C(C=CC=C2Cl)F)CC(=O)O Ambient Ambient "Windsor MA, Valk PL, Xu S, et al. Exploring the molecular determinants of substrate-selective inhibition of cyclooxygenase-2 by lumiracoxib. Bioorg Med Chem Lett. 2013 Nov 1;23(21):5860-4. PMID: 24060487.

 

Renna NF, Diez ER, Lembo C, et al. Role of Cox-2 in vascular inflammation: an experimental model of metabolic syndrome. Mediators Inflamm. 2013;2013:513251. PMID: 23476105.

 

Hao JQ, Li Q, Xu SP, et al. Effect of lumiracoxib on proliferation and apoptosis of human nonsmall cell lung cancer cells in vitro. Chin Med J (Engl). 2008 Apr 5;121(7):602-7. PMID: 18466679.

 

Selg E, Buccellati C, Andersson M, et al. Antagonism of thromboxane receptors by diclofenac and lumiracoxib. Br J Pharmacol. 2007 Dec;152(8):1185-95. Erratum in: Br J Pharmacol. 2008 Apr;153(8):1763. Ambrosio, E [corrected to Ambrosio, M]. PMID: 17965743.

 

Ni J, Shu YY, Zhu YN, et al. COX-2 inhibitors ameliorate experimental autoimmune encephalomyelitis through modulating IFN-gamma and IL-10 production by inhibiting T-bet expression. J Neuroimmunol. 2007 May;186(1-2):94-103. PMID: 17442406.

 

Esser R, Berry C, Du Z, et al. Preclinical pharmacology of lumiracoxib: a novel selective inhibitor of cyclooxygenase-2. Br J Pharmacol. 2005 Feb;144(4):538-50. PMID: 15655513.

" Not dangerous goods.

LKT T0108 10-Deacetyl-7-xylosyltaxol 10 mg 739.5 Taxane found in species of Taxus; potential microtubule depolymerization inhibitor. "10-Deacetyl-7-xylosyl paclitaxel,

10-Deacetylpaclitaxel 7-xyloside,

10-Deacetyltaxol 7-xyloside" 90332-63-1 ≥90% 943.98 C50H57NO17 Ambient -20°C "Hanson RL, Wasylyk JM, Nanduri VB, et al. Site-specific enzymatic hydrolysis of taxanes at C-10 and C-13. J Biol Chem. 1994 Sep 2;269(35):22145-9. PMID: 7915279.

 

Slichenmyer WJ, Von Hoff DD. New natural products in cancer chemotherapy. J Clin Pharmacol. 1990 Sep;30(9):770-88. PMID: 1980498.

" Not dangerous goods.

LKT T0108 10-Deacetyl-7-xylosyltaxol 25 mg 1386.1 Taxane found in species of Taxus; potential microtubule depolymerization inhibitor. "10-Deacetyl-7-xylosyl paclitaxel,

10-Deacetylpaclitaxel 7-xyloside,

10-Deacetyltaxol 7-xyloside" 90332-63-1 ≥90% 943.98 C50H57NO17 Ambient -20°C "Hanson RL, Wasylyk JM, Nanduri VB, et al. Site-specific enzymatic hydrolysis of taxanes at C-10 and C-13. J Biol Chem. 1994 Sep 2;269(35):22145-9. PMID: 7915279.

 

Slichenmyer WJ, Von Hoff DD. New natural products in cancer chemotherapy. J Clin Pharmacol. 1990 Sep;30(9):770-88. PMID: 1980498.

" Not dangerous goods.

LKT L8262 Lupinine 25 mg 81 Alkaloid found in species of Loranthus, Calia, and Lupinus; AChE and BChE inhibitor, potential CD69 activator. [1R-trans]-Octahydro-2H-quinolizine-1-methanol l-Lupine; (-)-Lupinine 486-70-4 ≥98% 169.26 C10H19NO C1CCN2CCCC(C2C1)CO Ambient 4°C Soluble in water, alcohol, chloroform and ether. "Basova NE, Kormilitsyn BN, Perchenok AIu, et al. Reversible lupininin inhibitors of cholinesterases of mammalian blood and of optical ganglia of individuals of the commander squid Berryteuthis magister from different zones of species areal. Zh Evol Biokhim Fiziol. 2012 May-Jun;48(3):213-8. PMID: 22827020.

 

Omeje EO, Osadebe PO, Nworu CS, et al. A novel sesquiterpene acid and an alkaloid from leaves of the Eastern Nigeria mistletoe, Loranthus micranthus with potent immunostimulatory activity on C57BL6 mice splenocytes and CD69 molecule. Pharm Biol. 2011 Dec;49(12):1271-6. PMID: 21988279.

 

Usmanova DM, Musaev UN, Efimov VS. Antiheparin activity of polymers based on the alkaloid, lupinine. Farmakol Toksikol. 1979 Nov-Dec;42(6):628-32. PMID: 499471.

" Xn "UN number: 1544     Class: 6.1     Packing Group: III

Proper shipping name: Alkaloids, solid, n.o.s. (Lupinine)"

LKT L8262 Lupinine 100 mg 265.8 Alkaloid found in species of Loranthus, Calia, and Lupinus; AChE and BChE inhibitor, potential CD69 activator. [1R-trans]-Octahydro-2H-quinolizine-1-methanol l-Lupine; (-)-Lupinine 486-70-4 ≥98% 169.26 C10H19NO C1CCN2CCCC(C2C1)CO Ambient 4°C Soluble in water, alcohol, chloroform and ether. "Basova NE, Kormilitsyn BN, Perchenok AIu, et al. Reversible lupininin inhibitors of cholinesterases of mammalian blood and of optical ganglia of individuals of the commander squid Berryteuthis magister from different zones of species areal. Zh Evol Biokhim Fiziol. 2012 May-Jun;48(3):213-8. PMID: 22827020.

 

Omeje EO, Osadebe PO, Nworu CS, et al. A novel sesquiterpene acid and an alkaloid from leaves of the Eastern Nigeria mistletoe, Loranthus micranthus with potent immunostimulatory activity on C57BL6 mice splenocytes and CD69 molecule. Pharm Biol. 2011 Dec;49(12):1271-6. PMID: 21988279.

 

Usmanova DM, Musaev UN, Efimov VS. Antiheparin activity of polymers based on the alkaloid, lupinine. Farmakol Toksikol. 1979 Nov-Dec;42(6):628-32. PMID: 499471.

" Xn "UN number: 1544     Class: 6.1     Packing Group: III

Proper shipping name: Alkaloids, solid, n.o.s. (Lupinine)"

LKT T0107 Xylosyltaxol C 5 mg 396.2 Taxane found in species of Taxus; potential microtubule depolymerization inhibitor. ≥90% 980.02 C51H65NO18 Ambient -20°C "Yu SS, Sun QW, Zhang XP, et al. Content and distribution of active components in cultivated and wild Taxus chinensis var. mairei plants. Ying Yong Sheng Tai Xue Bao. 2012 Oct;23(10):2641-7. PMID: 23359921.

 

Slichenmyer WJ, Von Hoff DD. New natural products in cancer chemotherapy. J Clin Pharmacol. 1990 Sep;30(9):770-88. PMID: 1980498.

" Not dangerous goods.

LKT T0107 Xylosyltaxol C 10 mg 633.8 Taxane found in species of Taxus; potential microtubule depolymerization inhibitor. ≥90% 980.02 C51H65NO18 Ambient -20°C "Yu SS, Sun QW, Zhang XP, et al. Content and distribution of active components in cultivated and wild Taxus chinensis var. mairei plants. Ying Yong Sheng Tai Xue Bao. 2012 Oct;23(10):2641-7. PMID: 23359921.

 

Slichenmyer WJ, Von Hoff DD. New natural products in cancer chemotherapy. J Clin Pharmacol. 1990 Sep;30(9):770-88. PMID: 1980498.

" Not dangerous goods.

LKT T0107 Xylosyltaxol C 25 mg 1237.6 Taxane found in species of Taxus; potential microtubule depolymerization inhibitor. ≥90% 980.02 C51H65NO18 Ambient -20°C "Yu SS, Sun QW, Zhang XP, et al. Content and distribution of active components in cultivated and wild Taxus chinensis var. mairei plants. Ying Yong Sheng Tai Xue Bao. 2012 Oct;23(10):2641-7. PMID: 23359921.

 

Slichenmyer WJ, Von Hoff DD. New natural products in cancer chemotherapy. J Clin Pharmacol. 1990 Sep;30(9):770-88. PMID: 1980498.

" Not dangerous goods.

LKT L8276 Luteinizing Hormone Releasing Hormone 1 mg 60 Endogenous peptide hormone; GnRH agonist. LHRH; Gonadoliberin; Luliberin; Nialutin 9034-40-6 ≥98% 1182.3 C55H76N17O13 CC(C)CC(C(=O)NC(CCCN=C(N)N)C(=O)N1CCCC1C(=O)NCC(=O)N)NC(=O)CNC(=O)C(CC2=CC=C(C=C2)O)NC(=O)C(CO)NC(=O)C(CC3=CNC4=CC=CC=C43)NC(=O)C(CC5=CN=CN5)NC(=O)C6CCC(=O)N6 Protect from moisture. Ambient -20°C Sol in 5% acetic acid "Limonta P, Manea M. Gonadotropin-releasing hormone receptors as molecular therapeutic targets in prostate cancer: Current options and emerging strategies. Cancer Treat Rev. 2013 Oct;39(6):647-63. PMID: 23290320.

 

Millar RP, Newton CL. Current and future applications of GnRH, kisspeptin and neurokinin B analogues. Nat Rev Endocrinol. 2013 Aug;9(8):451-66. PMID: 23817290.

 

Wu HM, Wang HS, Huang HY, et al. Gonadotropin-releasing hormone type II (GnRH-II) agonist regulates the invasiveness of endometrial cancer cells through the GnRH-I receptor and mitogen-activated protein kinase (MAPK)-dependent activation of matrix metalloproteinase (MMP)-2. BMC Cancer. 2013 Jun 20;13:300. PMID: 23786715.

 

Burel D, Li JH, Do-Rego JL, et al. Gonadotropin-releasing hormone stimulates the biosynthesis of pregnenolone sulfate and dehydroepiandrosterone sulfate in the hypothalamus. Endocrinology. 2013 Jun;154(6):2114-28. PMID: 23554453.

" Not dangerous goods.

LKT L8276 Luteinizing Hormone Releasing Hormone 2 mg 101.9 Endogenous peptide hormone; GnRH agonist. LHRH; Gonadoliberin; Luliberin; Nialutin 9034-40-6 ≥98% 1182.3 C55H76N17O13 CC(C)CC(C(=O)NC(CCCN=C(N)N)C(=O)N1CCCC1C(=O)NCC(=O)N)NC(=O)CNC(=O)C(CC2=CC=C(C=C2)O)NC(=O)C(CO)NC(=O)C(CC3=CNC4=CC=CC=C43)NC(=O)C(CC5=CN=CN5)NC(=O)C6CCC(=O)N6 Protect from moisture. Ambient -20°C Sol in 5% acetic acid "Limonta P, Manea M. Gonadotropin-releasing hormone receptors as molecular therapeutic targets in prostate cancer: Current options and emerging strategies. Cancer Treat Rev. 2013 Oct;39(6):647-63. PMID: 23290320.

 

Millar RP, Newton CL. Current and future applications of GnRH, kisspeptin and neurokinin B analogues. Nat Rev Endocrinol. 2013 Aug;9(8):451-66. PMID: 23817290.

 

Wu HM, Wang HS, Huang HY, et al. Gonadotropin-releasing hormone type II (GnRH-II) agonist regulates the invasiveness of endometrial cancer cells through the GnRH-I receptor and mitogen-activated protein kinase (MAPK)-dependent activation of matrix metalloproteinase (MMP)-2. BMC Cancer. 2013 Jun 20;13:300. PMID: 23786715.

 

Burel D, Li JH, Do-Rego JL, et al. Gonadotropin-releasing hormone stimulates the biosynthesis of pregnenolone sulfate and dehydroepiandrosterone sulfate in the hypothalamus. Endocrinology. 2013 Jun;154(6):2114-28. PMID: 23554453.

" Not dangerous goods.

LKT L8276 Luteinizing Hormone Releasing Hormone 5 mg 180 Endogenous peptide hormone; GnRH agonist. LHRH; Gonadoliberin; Luliberin; Nialutin 9034-40-6 ≥98% 1182.3 C55H76N17O13 CC(C)CC(C(=O)NC(CCCN=C(N)N)C(=O)N1CCCC1C(=O)NCC(=O)N)NC(=O)CNC(=O)C(CC2=CC=C(C=C2)O)NC(=O)C(CO)NC(=O)C(CC3=CNC4=CC=CC=C43)NC(=O)C(CC5=CN=CN5)NC(=O)C6CCC(=O)N6 Protect from moisture. Ambient -20°C Sol in 5% acetic acid "Limonta P, Manea M. Gonadotropin-releasing hormone receptors as molecular therapeutic targets in prostate cancer: Current options and emerging strategies. Cancer Treat Rev. 2013 Oct;39(6):647-63. PMID: 23290320.

 

Millar RP, Newton CL. Current and future applications of GnRH, kisspeptin and neurokinin B analogues. Nat Rev Endocrinol. 2013 Aug;9(8):451-66. PMID: 23817290.

 

Wu HM, Wang HS, Huang HY, et al. Gonadotropin-releasing hormone type II (GnRH-II) agonist regulates the invasiveness of endometrial cancer cells through the GnRH-I receptor and mitogen-activated protein kinase (MAPK)-dependent activation of matrix metalloproteinase (MMP)-2. BMC Cancer. 2013 Jun 20;13:300. PMID: 23786715.

 

Burel D, Li JH, Do-Rego JL, et al. Gonadotropin-releasing hormone stimulates the biosynthesis of pregnenolone sulfate and dehydroepiandrosterone sulfate in the hypothalamus. Endocrinology. 2013 Jun;154(6):2114-28. PMID: 23554453.

" Not dangerous goods.

LKT L8277 [Gln8]-Luteinizing Hormone Releasing Hormone, chicken 1 mg 60 Endogenous peptide hormone, involved in secretion of reproductive hormones; GnRH agonist. LHRH; GnRH 47922-48-5 ≥95% 1154.28 C54H71N15O14 CC(C)CC(C(=O)NC(CCC(=O)N)C(=O)N1CCCC1C(=O)NCC(=O)N)NC(=O)CNC(=O)C(CC2=CC=C(C=C2)O)NC(=O)C(CO)NC(=O)C(CC3=CNC4=CC=CC=C43)NC(=O)C(CC5=CN=CN5)NC(=O)C6CCC(=O)N6 Ambient -20°C "Limonta P, Manea M. Gonadotropin-releasing hormone receptors as molecular therapeutic targets in prostate cancer: Current options and emerging strategies. Cancer Treat Rev. 2013 Oct;39(6):647-63. PMID: 23290320.

 

Millar RP, Newton CL. Current and future applications of GnRH, kisspeptin and neurokinin B analogues. Nat Rev Endocrinol. 2013 Aug;9(8):451-66. PMID: 23817290.

 

Wu HM, Wang HS, Huang HY, et al. Gonadotropin-releasing hormone type II (GnRH-II) agonist regulates the invasiveness of endometrial cancer cells through the GnRH-I receptor and mitogen-activated protein kinase (MAPK)-dependent activation of matrix metalloproteinase (MMP)-2. BMC Cancer. 2013 Jun 20;13:300. PMID: 23786715.

 

Burel D, Li JH, Do-Rego JL, et al. Gonadotropin-releasing hormone stimulates the biosynthesis of pregnenolone sulfate and dehydroepiandrosterone sulfate in the hypothalamus. Endocrinology. 2013 Jun;154(6):2114-28. PMID: 23554453.

" Repr. Cat. 1, Repr. Cat. 2 Not dangerous goods.

LKT L8277 [Gln8]-Luteinizing Hormone Releasing Hormone, chicken 2 mg 101.9 Endogenous peptide hormone, involved in secretion of reproductive hormones; GnRH agonist. LHRH; GnRH 47922-48-5 ≥95% 1154.28 C54H71N15O14 CC(C)CC(C(=O)NC(CCC(=O)N)C(=O)N1CCCC1C(=O)NCC(=O)N)NC(=O)CNC(=O)C(CC2=CC=C(C=C2)O)NC(=O)C(CO)NC(=O)C(CC3=CNC4=CC=CC=C43)NC(=O)C(CC5=CN=CN5)NC(=O)C6CCC(=O)N6 Ambient -20°C "Limonta P, Manea M. Gonadotropin-releasing hormone receptors as molecular therapeutic targets in prostate cancer: Current options and emerging strategies. Cancer Treat Rev. 2013 Oct;39(6):647-63. PMID: 23290320.

 

Millar RP, Newton CL. Current and future applications of GnRH, kisspeptin and neurokinin B analogues. Nat Rev Endocrinol. 2013 Aug;9(8):451-66. PMID: 23817290.

 

Wu HM, Wang HS, Huang HY, et al. Gonadotropin-releasing hormone type II (GnRH-II) agonist regulates the invasiveness of endometrial cancer cells through the GnRH-I receptor and mitogen-activated protein kinase (MAPK)-dependent activation of matrix metalloproteinase (MMP)-2. BMC Cancer. 2013 Jun 20;13:300. PMID: 23786715.

 

Burel D, Li JH, Do-Rego JL, et al. Gonadotropin-releasing hormone stimulates the biosynthesis of pregnenolone sulfate and dehydroepiandrosterone sulfate in the hypothalamus. Endocrinology. 2013 Jun;154(6):2114-28. PMID: 23554453.

" Repr. Cat. 1, Repr. Cat. 2 Not dangerous goods.

LKT L8277 [Gln8]-Luteinizing Hormone Releasing Hormone, chicken 5 mg 180 Endogenous peptide hormone, involved in secretion of reproductive hormones; GnRH agonist. LHRH; GnRH 47922-48-5 ≥95% 1154.28 C54H71N15O14 CC(C)CC(C(=O)NC(CCC(=O)N)C(=O)N1CCCC1C(=O)NCC(=O)N)NC(=O)CNC(=O)C(CC2=CC=C(C=C2)O)NC(=O)C(CO)NC(=O)C(CC3=CNC4=CC=CC=C43)NC(=O)C(CC5=CN=CN5)NC(=O)C6CCC(=O)N6 Ambient -20°C "Limonta P, Manea M. Gonadotropin-releasing hormone receptors as molecular therapeutic targets in prostate cancer: Current options and emerging strategies. Cancer Treat Rev. 2013 Oct;39(6):647-63. PMID: 23290320.

 

Millar RP, Newton CL. Current and future applications of GnRH, kisspeptin and neurokinin B analogues. Nat Rev Endocrinol. 2013 Aug;9(8):451-66. PMID: 23817290.

 

Wu HM, Wang HS, Huang HY, et al. Gonadotropin-releasing hormone type II (GnRH-II) agonist regulates the invasiveness of endometrial cancer cells through the GnRH-I receptor and mitogen-activated protein kinase (MAPK)-dependent activation of matrix metalloproteinase (MMP)-2. BMC Cancer. 2013 Jun 20;13:300. PMID: 23786715.

 

Burel D, Li JH, Do-Rego JL, et al. Gonadotropin-releasing hormone stimulates the biosynthesis of pregnenolone sulfate and dehydroepiandrosterone sulfate in the hypothalamus. Endocrinology. 2013 Jun;154(6):2114-28. PMID: 23554453.

" Repr. Cat. 1, Repr. Cat. 2 Not dangerous goods.

LKT T0105 Taxol C 5 mg 396.2 Taxane synthesis intermediate. 153415-45-3 ≥94% 847.94 C46H57NO14 CCCCCC(=O)NC(C1=CC=CC=C1)C(C(=O)OC2CC3(C(C4C(C(CC5C4(CO5)OC(=O)C)O)(C(=O)C(C(=C2C)C3(C)C)OC(=O)C)C)OC(=O)C6=CC=CC=C6)O)O Ambient -20°C "Slichenmyer WJ, Von Hoff DD. New natural products in cancer chemotherapy. J Clin Pharmacol. 1990 Sep;30(9):770-88. PMID: 1980498.

 

Shen YC, Chen YJ, Chen CY. Taxane diterpenoids from the seeds of Chinese yew Taxus chinensis. Phytochemistry. 1999 Dec;52(8):1565-9. PMID: 10647221." Not dangerous goods.

LKT T0105 Taxol C 10 mg 633.8 Taxane synthesis intermediate. 153415-45-3 ≥94% 847.94 C46H57NO14 CCCCCC(=O)NC(C1=CC=CC=C1)C(C(=O)OC2CC3(C(C4C(C(CC5C4(CO5)OC(=O)C)O)(C(=O)C(C(=C2C)C3(C)C)OC(=O)C)C)OC(=O)C6=CC=CC=C6)O)O Ambient -20°C "Slichenmyer WJ, Von Hoff DD. New natural products in cancer chemotherapy. J Clin Pharmacol. 1990 Sep;30(9):770-88. PMID: 1980498.

 

Shen YC, Chen YJ, Chen CY. Taxane diterpenoids from the seeds of Chinese yew Taxus chinensis. Phytochemistry. 1999 Dec;52(8):1565-9. PMID: 10647221." Not dangerous goods.

LKT T0105 Taxol C 25 mg 1237.6 Taxane synthesis intermediate. 153415-45-3 ≥94% 847.94 C46H57NO14 CCCCCC(=O)NC(C1=CC=CC=C1)C(C(=O)OC2CC3(C(C4C(C(CC5C4(CO5)OC(=O)C)O)(C(=O)C(C(=C2C)C3(C)C)OC(=O)C)C)OC(=O)C6=CC=CC=C6)O)O Ambient -20°C "Slichenmyer WJ, Von Hoff DD. New natural products in cancer chemotherapy. J Clin Pharmacol. 1990 Sep;30(9):770-88. PMID: 1980498.

 

Shen YC, Chen YJ, Chen CY. Taxane diterpenoids from the seeds of Chinese yew Taxus chinensis. Phytochemistry. 1999 Dec;52(8):1565-9. PMID: 10647221." Not dangerous goods.

LKT L8278 Luteinizing Hormone Releasing Hormone, salmon 1 mg 60 Endogenous peptide hormone, involved in secretion of reproductive hormones; GnRH agonist. Gonadotropin-releasing hormone (salmon); LHRH; GnRH 86073-88-3 ≥95% 1212.36 C60H73N15O13 "CC(C)CC(C(=O)N1CCCC1C(=O)NCC(=O)N)NC(=O)C(Cc2c[nH]c3c2cccc3)NC(=O)CNC(=O)C(Cc4ccc(cc4)O)NC(=O)C(CO)NC(=O)C(Cc5c[nH]c6c5cccc6)NC(=O)C(Cc7cnc[nH]7)NC(=O)C8CCC(=O)N8

" Ambient -20°C "Limonta P, Manea M. Gonadotropin-releasing hormone receptors as molecular therapeutic targets in prostate cancer: Current options and emerging strategies. Cancer Treat Rev. 2013 Oct;39(6):647-63. PMID: 23290320.

 

Millar RP, Newton CL. Current and future applications of GnRH, kisspeptin and neurokinin B analogues. Nat Rev Endocrinol. 2013 Aug;9(8):451-66. PMID: 23817290.

 

Wu HM, Wang HS, Huang HY, et al. Gonadotropin-releasing hormone type II (GnRH-II) agonist regulates the invasiveness of endometrial cancer cells through the GnRH-I receptor and mitogen-activated protein kinase (MAPK)-dependent activation of matrix metalloproteinase (MMP)-2. BMC Cancer. 2013 Jun 20;13:300. PMID: 23786715.

 

Burel D, Li JH, Do-Rego JL, et al. Gonadotropin-releasing hormone stimulates the biosynthesis of pregnenolone sulfate and dehydroepiandrosterone sulfate in the hypothalamus. Endocrinology. 2013 Jun;154(6):2114-28. PMID: 23554453.

" Repr. Cat. 1, Repr. Cat. 2 Not dangerous goods.

LKT L8278 Luteinizing Hormone Releasing Hormone, salmon 2 mg 101.9 Endogenous peptide hormone, involved in secretion of reproductive hormones; GnRH agonist. Gonadotropin-releasing hormone (salmon); LHRH; GnRH 86073-88-3 ≥95% 1212.36 C60H73N15O13 "CC(C)CC(C(=O)N1CCCC1C(=O)NCC(=O)N)NC(=O)C(Cc2c[nH]c3c2cccc3)NC(=O)CNC(=O)C(Cc4ccc(cc4)O)NC(=O)C(CO)NC(=O)C(Cc5c[nH]c6c5cccc6)NC(=O)C(Cc7cnc[nH]7)NC(=O)C8CCC(=O)N8

" Ambient -20°C "Limonta P, Manea M. Gonadotropin-releasing hormone receptors as molecular therapeutic targets in prostate cancer: Current options and emerging strategies. Cancer Treat Rev. 2013 Oct;39(6):647-63. PMID: 23290320.

 

Millar RP, Newton CL. Current and future applications of GnRH, kisspeptin and neurokinin B analogues. Nat Rev Endocrinol. 2013 Aug;9(8):451-66. PMID: 23817290.

 

Wu HM, Wang HS, Huang HY, et al. Gonadotropin-releasing hormone type II (GnRH-II) agonist regulates the invasiveness of endometrial cancer cells through the GnRH-I receptor and mitogen-activated protein kinase (MAPK)-dependent activation of matrix metalloproteinase (MMP)-2. BMC Cancer. 2013 Jun 20;13:300. PMID: 23786715.

 

Burel D, Li JH, Do-Rego JL, et al. Gonadotropin-releasing hormone stimulates the biosynthesis of pregnenolone sulfate and dehydroepiandrosterone sulfate in the hypothalamus. Endocrinology. 2013 Jun;154(6):2114-28. PMID: 23554453.

" Repr. Cat. 1, Repr. Cat. 2 Not dangerous goods.

LKT L8278 Luteinizing Hormone Releasing Hormone, salmon 5 mg 180 Endogenous peptide hormone, involved in secretion of reproductive hormones; GnRH agonist. Gonadotropin-releasing hormone (salmon); LHRH; GnRH 86073-88-3 ≥95% 1212.36 C60H73N15O13 "CC(C)CC(C(=O)N1CCCC1C(=O)NCC(=O)N)NC(=O)C(Cc2c[nH]c3c2cccc3)NC(=O)CNC(=O)C(Cc4ccc(cc4)O)NC(=O)C(CO)NC(=O)C(Cc5c[nH]c6c5cccc6)NC(=O)C(Cc7cnc[nH]7)NC(=O)C8CCC(=O)N8

" Ambient -20°C "Limonta P, Manea M. Gonadotropin-releasing hormone receptors as molecular therapeutic targets in prostate cancer: Current options and emerging strategies. Cancer Treat Rev. 2013 Oct;39(6):647-63. PMID: 23290320.

 

Millar RP, Newton CL. Current and future applications of GnRH, kisspeptin and neurokinin B analogues. Nat Rev Endocrinol. 2013 Aug;9(8):451-66. PMID: 23817290.

 

Wu HM, Wang HS, Huang HY, et al. Gonadotropin-releasing hormone type II (GnRH-II) agonist regulates the invasiveness of endometrial cancer cells through the GnRH-I receptor and mitogen-activated protein kinase (MAPK)-dependent activation of matrix metalloproteinase (MMP)-2. BMC Cancer. 2013 Jun 20;13:300. PMID: 23786715.

 

Burel D, Li JH, Do-Rego JL, et al. Gonadotropin-releasing hormone stimulates the biosynthesis of pregnenolone sulfate and dehydroepiandrosterone sulfate in the hypothalamus. Endocrinology. 2013 Jun;154(6):2114-28. PMID: 23554453.

" Repr. Cat. 1, Repr. Cat. 2 Not dangerous goods.

LKT L8377 Luteolin 100 mg 92.5 Flavonoid found in various plant sources; DAT and NET potentiator, HSP90, IGF-1R, PDE inhibitor, potential α2-adrenergic antagonist. 2-(3,4-Dihydroxyphenyl)-5,7-dihydroxy-4H-1- benzopyran-4-one 3',4',5,7-Tetrahydroxyflavone; Digitoflavone; Cyanidenon 491-70-3 ≥95% 286.24 C15H10O6 C1=CC(=C(C=C1C2=CC(=O)C3=C(C=C(C=C3O2)O)O)O)O Ambient 4°C Soluble in methanol and alkaline solutions.  Slightly soluble in water. DMSO to 57 mg/mL, Ethanol to 6mg/mL "Xu N, Zhang L, Dong J, et al. Low-dose diet supplement of a natural flavonoid, luteolin, ameliorates diet-induced obesity and insulin resistance in mice. Mol Nutr Food Res. 2014 Jun;58(6):1258-68. PMID: 24668788.

 

Chen D, Bi A, Dong X, et al. Luteolin exhibits anti-inflammatory effects by blocking the activity of heat shock protein 90 in macrophages. Biochem Biophys Res Commun. 2014 Jan 3;443(1):326-32. PMID: 24321097.

 

Lv GY, Zhang YP, Gao JL, et al. Combined antihypertensive effect of luteolin and buddleoside enriched extracts in spontaneously hypertensive rats. J Ethnopharmacol. 2013 Nov 25;150(2):507-13. PMID: 24080032.

 

Yang Y, Shen J, Yu X, et al. Identification of an inhibitory mechanism of luteolin on the insulin-like growth factor-1 ligand-receptor interaction. Chembiochem. 2013 May 27;14(8):929-33. PMID: 23630137.

 

Lu XY, Li YH, Xiao XW, et al. Inhibitory effects of luteolin on human gastric carcinoma xenografts in nude mice and its mechanism. Zhonghua Yi Xue Za Zhi. 2013 Jan 8;93(2):142-6. PMID: 23648354.

 

Yu MC, Chen JH, Lai CY, et al. Luteolin, a non-selective competitive inhibitor of phosphodiesterases 1-5, displaced [3H]-rolipram from high-affinity rolipram binding sites and reversed xylazine/ketamine-induced anesthesia. Eur J Pharmacol. 2010 Feb 10;627(1-3):269-75. PMID: 19853596.

 

Zhao G, Qin GW, Wang J, et al. Functional activation of monoamine transporters by luteolin and apigenin isolated from the fruit of Perilla frutescens (L.) Britt. Neurochem Int. 2010 Jan;56(1):168-76. PMID: 19815045.

 

Theoharides TC. Luteolin as a therapeutic option for multiple sclerosis. J Neuroinflammation. 2009 Oct 13;6:29. PMID: 19825165.

 

Jang S, Kelley KW, Johnson RW. Luteolin reduces IL-6 production in microglia by inhibiting JNK phosphorylation and activation of AP-1. Proc Natl Acad Sci U S A. 2008 May 27;105(21):7534-9. PMID: 18490655.

 

Kang KP, Park SK, Kim DH, et al. Luteolin ameliorates cisplatin-induced acute kidney injury in mice by regulation of p53-dependent renal tubular apoptosis. Nephrol Dial Transplant. 2011 Mar;26(3):814-822. PMID: 20817674.

" Xi Not dangerous goods.

LKT L8377 Luteolin 500 mg 288.8 Flavonoid found in various plant sources; DAT and NET potentiator, HSP90, IGF-1R, PDE inhibitor, potential α2-adrenergic antagonist. 2-(3,4-Dihydroxyphenyl)-5,7-dihydroxy-4H-1- benzopyran-4-one 3',4',5,7-Tetrahydroxyflavone; Digitoflavone; Cyanidenon 491-70-3 ≥95% 286.24 C15H10O6 C1=CC(=C(C=C1C2=CC(=O)C3=C(C=C(C=C3O2)O)O)O)O Ambient 4°C Soluble in methanol and alkaline solutions.  Slightly soluble in water. DMSO to 57 mg/mL, Ethanol to 6mg/mL "Xu N, Zhang L, Dong J, et al. Low-dose diet supplement of a natural flavonoid, luteolin, ameliorates diet-induced obesity and insulin resistance in mice. Mol Nutr Food Res. 2014 Jun;58(6):1258-68. PMID: 24668788.

 

Chen D, Bi A, Dong X, et al. Luteolin exhibits anti-inflammatory effects by blocking the activity of heat shock protein 90 in macrophages. Biochem Biophys Res Commun. 2014 Jan 3;443(1):326-32. PMID: 24321097.

 

Lv GY, Zhang YP, Gao JL, et al. Combined antihypertensive effect of luteolin and buddleoside enriched extracts in spontaneously hypertensive rats. J Ethnopharmacol. 2013 Nov 25;150(2):507-13. PMID: 24080032.

 

Yang Y, Shen J, Yu X, et al. Identification of an inhibitory mechanism of luteolin on the insulin-like growth factor-1 ligand-receptor interaction. Chembiochem. 2013 May 27;14(8):929-33. PMID: 23630137.

 

Lu XY, Li YH, Xiao XW, et al. Inhibitory effects of luteolin on human gastric carcinoma xenografts in nude mice and its mechanism. Zhonghua Yi Xue Za Zhi. 2013 Jan 8;93(2):142-6. PMID: 23648354.

 

Yu MC, Chen JH, Lai CY, et al. Luteolin, a non-selective competitive inhibitor of phosphodiesterases 1-5, displaced [3H]-rolipram from high-affinity rolipram binding sites and reversed xylazine/ketamine-induced anesthesia. Eur J Pharmacol. 2010 Feb 10;627(1-3):269-75. PMID: 19853596.

 

Zhao G, Qin GW, Wang J, et al. Functional activation of monoamine transporters by luteolin and apigenin isolated from the fruit of Perilla frutescens (L.) Britt. Neurochem Int. 2010 Jan;56(1):168-76. PMID: 19815045.

 

Theoharides TC. Luteolin as a therapeutic option for multiple sclerosis. J Neuroinflammation. 2009 Oct 13;6:29. PMID: 19825165.

 

Jang S, Kelley KW, Johnson RW. Luteolin reduces IL-6 production in microglia by inhibiting JNK phosphorylation and activation of AP-1. Proc Natl Acad Sci U S A. 2008 May 27;105(21):7534-9. PMID: 18490655.

 

Kang KP, Park SK, Kim DH, et al. Luteolin ameliorates cisplatin-induced acute kidney injury in mice by regulation of p53-dependent renal tubular apoptosis. Nephrol Dial Transplant. 2011 Mar;26(3):814-822. PMID: 20817674.

" Xi Not dangerous goods.

LKT L8377 Luteolin 1 g 404.5 Flavonoid found in various plant sources; DAT and NET potentiator, HSP90, IGF-1R, PDE inhibitor, potential α2-adrenergic antagonist. 2-(3,4-Dihydroxyphenyl)-5,7-dihydroxy-4H-1- benzopyran-4-one 3',4',5,7-Tetrahydroxyflavone; Digitoflavone; Cyanidenon 491-70-3 ≥95% 286.24 C15H10O6 C1=CC(=C(C=C1C2=CC(=O)C3=C(C=C(C=C3O2)O)O)O)O Ambient 4°C Soluble in methanol and alkaline solutions.  Slightly soluble in water. DMSO to 57 mg/mL, Ethanol to 6mg/mL "Xu N, Zhang L, Dong J, et al. Low-dose diet supplement of a natural flavonoid, luteolin, ameliorates diet-induced obesity and insulin resistance in mice. Mol Nutr Food Res. 2014 Jun;58(6):1258-68. PMID: 24668788.

 

Chen D, Bi A, Dong X, et al. Luteolin exhibits anti-inflammatory effects by blocking the activity of heat shock protein 90 in macrophages. Biochem Biophys Res Commun. 2014 Jan 3;443(1):326-32. PMID: 24321097.

 

Lv GY, Zhang YP, Gao JL, et al. Combined antihypertensive effect of luteolin and buddleoside enriched extracts in spontaneously hypertensive rats. J Ethnopharmacol. 2013 Nov 25;150(2):507-13. PMID: 24080032.

 

Yang Y, Shen J, Yu X, et al. Identification of an inhibitory mechanism of luteolin on the insulin-like growth factor-1 ligand-receptor interaction. Chembiochem. 2013 May 27;14(8):929-33. PMID: 23630137.

 

Lu XY, Li YH, Xiao XW, et al. Inhibitory effects of luteolin on human gastric carcinoma xenografts in nude mice and its mechanism. Zhonghua Yi Xue Za Zhi. 2013 Jan 8;93(2):142-6. PMID: 23648354.

 

Yu MC, Chen JH, Lai CY, et al. Luteolin, a non-selective competitive inhibitor of phosphodiesterases 1-5, displaced [3H]-rolipram from high-affinity rolipram binding sites and reversed xylazine/ketamine-induced anesthesia. Eur J Pharmacol. 2010 Feb 10;627(1-3):269-75. PMID: 19853596.

 

Zhao G, Qin GW, Wang J, et al. Functional activation of monoamine transporters by luteolin and apigenin isolated from the fruit of Perilla frutescens (L.) Britt. Neurochem Int. 2010 Jan;56(1):168-76. PMID: 19815045.

 

Theoharides TC. Luteolin as a therapeutic option for multiple sclerosis. J Neuroinflammation. 2009 Oct 13;6:29. PMID: 19825165.

 

Jang S, Kelley KW, Johnson RW. Luteolin reduces IL-6 production in microglia by inhibiting JNK phosphorylation and activation of AP-1. Proc Natl Acad Sci U S A. 2008 May 27;105(21):7534-9. PMID: 18490655.

 

Kang KP, Park SK, Kim DH, et al. Luteolin ameliorates cisplatin-induced acute kidney injury in mice by regulation of p53-dependent renal tubular apoptosis. Nephrol Dial Transplant. 2011 Mar;26(3):814-822. PMID: 20817674.

" Xi Not dangerous goods.

LKT T0104 Taxol Side Chain Methyl Ester 5 mg 242.7 Side chain attached to various taxanes. ≥96% 299.32 C17H18NO4 Ambient -20°C Shen YC, Chen YJ, Chen CY. Taxane diterpenoids from the seeds of Chinese yew Taxus chinensis. Phytochemistry. 1999 Dec;52(8):1565-9. PMID: 10647221. Not dangerous goods.

LKT T0104 Taxol Side Chain Methyl Ester 10 mg 434.4 Side chain attached to various taxanes. ≥96% 299.32 C17H18NO4 Ambient -20°C Shen YC, Chen YJ, Chen CY. Taxane diterpenoids from the seeds of Chinese yew Taxus chinensis. Phytochemistry. 1999 Dec;52(8):1565-9. PMID: 10647221. Not dangerous goods.

LKT T0104 Taxol Side Chain Methyl Ester 25 mg 849.3 Side chain attached to various taxanes. ≥96% 299.32 C17H18NO4 Ambient -20°C Shen YC, Chen YJ, Chen CY. Taxane diterpenoids from the seeds of Chinese yew Taxus chinensis. Phytochemistry. 1999 Dec;52(8):1565-9. PMID: 10647221. Not dangerous goods.

LKT L9609 Lycopene 1 mg 160 Carotene pigment found in red and green fruits and vegetables; RAR agonist. ψ,ψ-Carotene all-trans-Lycopene; Lycopene 7 502-65-8 ≥90% 536.88 C40H56 CC(=CCCC(=CC=CC(=CC=CC(=CC=CC=C(C)C=CC=C(C)C=CC=C(C)CCC=C(C)C)C)C)C)C Heat sensitive. Protect from light. Dry Ice -80°C Insoluble in water. Sparingly soluble in ethanol. Soluble in carbon disulfide, chloroform and benzene. "Chao HH, Sung LC, Chen CH, et al. Lycopene Inhibits Urotensin-II-Induced Cardiomyocyte Hypertrophy in Neonatal Rat Cardiomyocytes. Evid Based Complement Alternat Med. 2014;2014:724670. PMID: 24971153.

 

Gloria NF, Soares N, Brand C, et al. Lycopene and beta-carotene induce cell-cycle arrest and apoptosis in human breast cancer cell lines. Anticancer Res. 2014 Mar;34(3):1377-86. PMID: 24596385.

 

Bayramoglu G, Bayramoglu A, Altuner Y, et al. The effects of lycopene on hepatic ischemia/reperfusion injury in rats. Cytotechnology. 2014 Mar 4. [Epub ahead of print]. PMID: 24590927.

 

Aydemir G, Carlsen H, Blomhoff R, et al. Lycopene induces retinoic acid receptor transcriptional activation in mice. Mol Nutr Food Res. 2012 May;56(5):702-12. PMID: 22648617.

" None Not dangerous goods.

LKT L9609 Lycopene 5 mg 560 Carotene pigment found in red and green fruits and vegetables; RAR agonist. ψ,ψ-Carotene all-trans-Lycopene; Lycopene 7 502-65-8 ≥90% 536.88 C40H56 CC(=CCCC(=CC=CC(=CC=CC(=CC=CC=C(C)C=CC=C(C)C=CC=C(C)CCC=C(C)C)C)C)C)C Heat sensitive. Protect from light. Dry Ice -80°C Insoluble in water. Sparingly soluble in ethanol. Soluble in carbon disulfide, chloroform and benzene. "Chao HH, Sung LC, Chen CH, et al. Lycopene Inhibits Urotensin-II-Induced Cardiomyocyte Hypertrophy in Neonatal Rat Cardiomyocytes. Evid Based Complement Alternat Med. 2014;2014:724670. PMID: 24971153.

 

Gloria NF, Soares N, Brand C, et al. Lycopene and beta-carotene induce cell-cycle arrest and apoptosis in human breast cancer cell lines. Anticancer Res. 2014 Mar;34(3):1377-86. PMID: 24596385.

 

Bayramoglu G, Bayramoglu A, Altuner Y, et al. The effects of lycopene on hepatic ischemia/reperfusion injury in rats. Cytotechnology. 2014 Mar 4. [Epub ahead of print]. PMID: 24590927.

 

Aydemir G, Carlsen H, Blomhoff R, et al. Lycopene induces retinoic acid receptor transcriptional activation in mice. Mol Nutr Food Res. 2012 May;56(5):702-12. PMID: 22648617.

" None Not dangerous goods.

LKT T0103 Taxol Side Chain Diol 5 mg 248.7 Side chain attached to various taxanes. ≥98% 271.34 C16H17NO3 Ambient -20°C Shen YC, Chen YJ, Chen CY. Taxane diterpenoids from the seeds of Chinese yew Taxus chinensis. Phytochemistry. 1999 Dec;52(8):1565-9. PMID: 10647221. Not dangerous goods.

LKT T0103 Taxol Side Chain Diol 10 mg 436.8 Side chain attached to various taxanes. ≥98% 271.34 C16H17NO3 Ambient -20°C Shen YC, Chen YJ, Chen CY. Taxane diterpenoids from the seeds of Chinese yew Taxus chinensis. Phytochemistry. 1999 Dec;52(8):1565-9. PMID: 10647221. Not dangerous goods.

LKT T0103 Taxol Side Chain Diol 25 mg 873.6 Side chain attached to various taxanes. ≥98% 271.34 C16H17NO3 Ambient -20°C Shen YC, Chen YJ, Chen CY. Taxane diterpenoids from the seeds of Chinese yew Taxus chinensis. Phytochemistry. 1999 Dec;52(8):1565-9. PMID: 10647221. Not dangerous goods.

LKT L9874 L-(+)-Lysine Monohydrate 5 g 43.5 Non-endogenous essential amino acid found in meat, soy, dairy, required for production of collagen, acetyl-CoA, proteins, antibodies, and hormones. L(+)-2,6-Diaminocaproic acid L-Lysine monohydrate; L-Lysine hydrate; H-Lys-OH.H2O 39665-12-8 ≥95% 164.2 C6H14N2O2 H2O C(CCN)CC(C(=O)O)N.O Ambient Ambient Soluble in water (300 g/L). "Sadoul K, Boyault C, Pabion M, et al. Regulation of protein turnover by acetyltransferases and deacetylases. Biochimie. 2008 Feb;90(2):306-12. PMID: 17681659.

 

Smriga M, Kameishi M, Uneyama H, et al. Dietary L-lysine deficiency increases stress-induced anxiety and fecal excretion in rats. J Nutr. 2002 Dec;132(12):3744-6. PMID: 12468617.

 

Young VR, Pellett PL. Plant proteins in relation to human protein and amino acid nutrition. Am J Clin Nutr. 1994 May;59(5 Suppl):1203S-1212S. PMID: 8172124.

" None Not dangerous goods.

LKT L9874 L-(+)-Lysine Monohydrate 25 g 81.6 Non-endogenous essential amino acid found in meat, soy, dairy, required for production of collagen, acetyl-CoA, proteins, antibodies, and hormones. L(+)-2,6-Diaminocaproic acid L-Lysine monohydrate; L-Lysine hydrate; H-Lys-OH.H2O 39665-12-8 ≥95% 164.2 C6H14N2O2 H2O C(CCN)CC(C(=O)O)N.O Ambient Ambient Soluble in water (300 g/L). "Sadoul K, Boyault C, Pabion M, et al. Regulation of protein turnover by acetyltransferases and deacetylases. Biochimie. 2008 Feb;90(2):306-12. PMID: 17681659.

 

Smriga M, Kameishi M, Uneyama H, et al. Dietary L-lysine deficiency increases stress-induced anxiety and fecal excretion in rats. J Nutr. 2002 Dec;132(12):3744-6. PMID: 12468617.

 

Young VR, Pellett PL. Plant proteins in relation to human protein and amino acid nutrition. Am J Clin Nutr. 1994 May;59(5 Suppl):1203S-1212S. PMID: 8172124.

" None Not dangerous goods.

LKT L9874 L-(+)-Lysine Monohydrate 100 g 271.7 Non-endogenous essential amino acid found in meat, soy, dairy, required for production of collagen, acetyl-CoA, proteins, antibodies, and hormones. L(+)-2,6-Diaminocaproic acid L-Lysine monohydrate; L-Lysine hydrate; H-Lys-OH.H2O 39665-12-8 ≥95% 164.2 C6H14N2O2 H2O C(CCN)CC(C(=O)O)N.O Ambient Ambient Soluble in water (300 g/L). "Sadoul K, Boyault C, Pabion M, et al. Regulation of protein turnover by acetyltransferases and deacetylases. Biochimie. 2008 Feb;90(2):306-12. PMID: 17681659.

 

Smriga M, Kameishi M, Uneyama H, et al. Dietary L-lysine deficiency increases stress-induced anxiety and fecal excretion in rats. J Nutr. 2002 Dec;132(12):3744-6. PMID: 12468617.

 

Young VR, Pellett PL. Plant proteins in relation to human protein and amino acid nutrition. Am J Clin Nutr. 1994 May;59(5 Suppl):1203S-1212S. PMID: 8172124.

" None Not dangerous goods.

LKT L9875 Lys(Boc)-Leu-Lys(Boc)-Obzl 1 g 1500.2 Proteinase substrate. ≥98% 667.9 C35H59N5O8 Ambient -20°C

LKT T0099 10-Deacetylbaccatin-III 5 mg 369.8 Diterpene found in Taxus. 10-DB III; 10-Deacetylbaccatine III 32981-86-5 ≥98% 544.59 C29H36O10 CC1=C2C(C(=O)C3(C(CC4C(C3C(C(C2(C)C)(CC1O)O)OC(=O)C5=CC=CC=C5)(CO4)OC(=O)C)O)C)O Ambient -20°C Soluble in DMSO. "Qayum M, Nisar M, Shah MR, et al. Analgesic and antiinflammatory activities of taxoids from Taxus wallichiana Zucc. Phytother Res. 2012 Apr;26(4):552-6. PMID: 21953729.

 

Georgopoulou K, Smirlis D, Bisti S, et al. In vitro activity of 10-deacetylbaccatin III against Leishmania donovani promastigotes and intracellular amastigotes. Planta Med. 2007 Aug;73(10):1081-8. PMID: 17691059.

" T Not dangerous goods.

LKT T0099 10-Deacetylbaccatin-III 10 mg 591.4 Diterpene found in Taxus. 10-DB III; 10-Deacetylbaccatine III 32981-86-5 ≥98% 544.59 C29H36O10 CC1=C2C(C(=O)C3(C(CC4C(C3C(C(C2(C)C)(CC1O)O)OC(=O)C5=CC=CC=C5)(CO4)OC(=O)C)O)C)O Ambient -20°C Soluble in DMSO. "Qayum M, Nisar M, Shah MR, et al. Analgesic and antiinflammatory activities of taxoids from Taxus wallichiana Zucc. Phytother Res. 2012 Apr;26(4):552-6. PMID: 21953729.

 

Georgopoulou K, Smirlis D, Bisti S, et al. In vitro activity of 10-deacetylbaccatin III against Leishmania donovani promastigotes and intracellular amastigotes. Planta Med. 2007 Aug;73(10):1081-8. PMID: 17691059.

" T Not dangerous goods.

LKT T0099 10-Deacetylbaccatin-III 25 mg 1155.2 Diterpene found in Taxus. 10-DB III; 10-Deacetylbaccatine III 32981-86-5 ≥98% 544.59 C29H36O10 CC1=C2C(C(=O)C3(C(CC4C(C3C(C(C2(C)C)(CC1O)O)OC(=O)C5=CC=CC=C5)(CO4)OC(=O)C)O)C)O Ambient -20°C Soluble in DMSO. "Qayum M, Nisar M, Shah MR, et al. Analgesic and antiinflammatory activities of taxoids from Taxus wallichiana Zucc. Phytother Res. 2012 Apr;26(4):552-6. PMID: 21953729.

 

Georgopoulou K, Smirlis D, Bisti S, et al. In vitro activity of 10-deacetylbaccatin III against Leishmania donovani promastigotes and intracellular amastigotes. Planta Med. 2007 Aug;73(10):1081-8. PMID: 17691059.

" T Not dangerous goods.

LKT M0035 M35 0.5 mg 228 Peptide; galanin antagonist. Galanin-(1-13)-bradykinin-(2-9)-amide 142846-71-7 ≥95% 2233.58 C107H153N27O26 CC(C)CC(C(=O)NC(CC(C)C)C(=O)NCC(=O)N1CCCC1C(=O)N2CCCC2C(=O)N3CCCC3C(=O)NCC(=O)NC(CC4=CC=CC=C4)C(=O)NC(CO)C(=O)N5CCCC5C(=O)NC(CC6=CC=CC=C6)C(=O)NC(CCCNC(=N)N)C(=O)N)NC(=O)C(CC7=CC=C(C=C7)O)NC(=O)CNC(=O)C(C)NC(=O)C(CO)NC(=O)C(CC(=O)N)NC(=O)C(CC(C)C)NC(=O)C(C(C)O)NC(=O)C(CC8=CNC9=CC=CC=C98)NC(=O)CN Ambient -20°C "Bu L, Liu Z, Zou J, et al. Blocking central galanin receptors attenuates insulin sensitivity in myocytes of diabetic trained rats. J Neurosci Res. 2013 Jul;91(7):971-7. PMID: 23653288.

 

Bhandari M, Kawamoto M, Thomas AC, et al. Galanin receptor antagonist m35 but not m40 or c7 ameliorates cerulein-induced acute pancreatitis in mice. Pancreatology. 2010;10(6):682-8. PMID: 21242707.

 

Jiang L, Shi M, Guo L, et al. Effect of M35, a neuropeptide galanin antagonist on glucose uptake translated by glucose transporter 4 in trained rat skeletal muscle. Neurosci Lett. 2009 Dec 25;467(2):178-81. PMID: 19835935.

 

Kuteeva E, Wardi T, Hökfelt T, et al. Galanin enhances and a galanin antagonist attenuates depression-like behaviour in the rat. Eur Neuropsychopharmacol. 2007 Jan;17(1):64-9. PMID: 16624535.

 

Ogren SO, Hökfelt T, Kask K, et al. Evidence for a role of the neuropeptide galanin in spatial learning. Neuroscience. 1992 Nov;51(1):1-5. PMID: 1281521.

"

LKT M0035 M35 1 mg 387 Peptide; galanin antagonist. Galanin-(1-13)-bradykinin-(2-9)-amide 142846-71-7 ≥95% 2233.58 C107H153N27O26 CC(C)CC(C(=O)NC(CC(C)C)C(=O)NCC(=O)N1CCCC1C(=O)N2CCCC2C(=O)N3CCCC3C(=O)NCC(=O)NC(CC4=CC=CC=C4)C(=O)NC(CO)C(=O)N5CCCC5C(=O)NC(CC6=CC=CC=C6)C(=O)NC(CCCNC(=N)N)C(=O)N)NC(=O)C(CC7=CC=C(C=C7)O)NC(=O)CNC(=O)C(C)NC(=O)C(CO)NC(=O)C(CC(=O)N)NC(=O)C(CC(C)C)NC(=O)C(C(C)O)NC(=O)C(CC8=CNC9=CC=CC=C98)NC(=O)CN Ambient -20°C "Bu L, Liu Z, Zou J, et al. Blocking central galanin receptors attenuates insulin sensitivity in myocytes of diabetic trained rats. J Neurosci Res. 2013 Jul;91(7):971-7. PMID: 23653288.

 

Bhandari M, Kawamoto M, Thomas AC, et al. Galanin receptor antagonist m35 but not m40 or c7 ameliorates cerulein-induced acute pancreatitis in mice. Pancreatology. 2010;10(6):682-8. PMID: 21242707.

 

Jiang L, Shi M, Guo L, et al. Effect of M35, a neuropeptide galanin antagonist on glucose uptake translated by glucose transporter 4 in trained rat skeletal muscle. Neurosci Lett. 2009 Dec 25;467(2):178-81. PMID: 19835935.

 

Kuteeva E, Wardi T, Hökfelt T, et al. Galanin enhances and a galanin antagonist attenuates depression-like behaviour in the rat. Eur Neuropsychopharmacol. 2007 Jan;17(1):64-9. PMID: 16624535.

 

Ogren SO, Hökfelt T, Kask K, et al. Evidence for a role of the neuropeptide galanin in spatial learning. Neuroscience. 1992 Nov;51(1):1-5. PMID: 1281521.

"

LKT M0035 M35 2.5 mg 684.1 Peptide; galanin antagonist. Galanin-(1-13)-bradykinin-(2-9)-amide 142846-71-7 ≥95% 2233.58 C107H153N27O26 CC(C)CC(C(=O)NC(CC(C)C)C(=O)NCC(=O)N1CCCC1C(=O)N2CCCC2C(=O)N3CCCC3C(=O)NCC(=O)NC(CC4=CC=CC=C4)C(=O)NC(CO)C(=O)N5CCCC5C(=O)NC(CC6=CC=CC=C6)C(=O)NC(CCCNC(=N)N)C(=O)N)NC(=O)C(CC7=CC=C(C=C7)O)NC(=O)CNC(=O)C(C)NC(=O)C(CO)NC(=O)C(CC(=O)N)NC(=O)C(CC(C)C)NC(=O)C(C(C)O)NC(=O)C(CC8=CNC9=CC=CC=C98)NC(=O)CN Ambient -20°C "Bu L, Liu Z, Zou J, et al. Blocking central galanin receptors attenuates insulin sensitivity in myocytes of diabetic trained rats. J Neurosci Res. 2013 Jul;91(7):971-7. PMID: 23653288.

 

Bhandari M, Kawamoto M, Thomas AC, et al. Galanin receptor antagonist m35 but not m40 or c7 ameliorates cerulein-induced acute pancreatitis in mice. Pancreatology. 2010;10(6):682-8. PMID: 21242707.

 

Jiang L, Shi M, Guo L, et al. Effect of M35, a neuropeptide galanin antagonist on glucose uptake translated by glucose transporter 4 in trained rat skeletal muscle. Neurosci Lett. 2009 Dec 25;467(2):178-81. PMID: 19835935.

 

Kuteeva E, Wardi T, Hökfelt T, et al. Galanin enhances and a galanin antagonist attenuates depression-like behaviour in the rat. Eur Neuropsychopharmacol. 2007 Jan;17(1):64-9. PMID: 16624535.

 

Ogren SO, Hökfelt T, Kask K, et al. Evidence for a role of the neuropeptide galanin in spatial learning. Neuroscience. 1992 Nov;51(1):1-5. PMID: 1281521.

"

LKT M0040 M40 0.5 mg 228 Peptide; galanin antagonist. 64: PN:US20050009742 PAGE: 20 claimed sequence 143896-17-7 ≥95% 1981.34 C94H145N23O24 CC(C)CC(C(=O)NC(C)C(=O)NC(CC(C)C)C(=O)NC(C)C(=O)N)NC(=O)C(C)NC(=O)C1CCCN1C(=O)C2CCCN2C(=O)C3CCCN3C(=O)CNC(=O)C(CC(C)C)NC(=O)C(CC(C)C)NC(=O)C(CC4=CC=C(C=C4)O)NC(=O)CNC(=O)C(C)NC(=O)C(CO)NC(=O)C(CC(=O)N)NC(=O)C(CC(C)C)NC(=O)C(C(C)O)NC(=O)C(CC5=CNC6=CC=CC=C65)NC(=O)CN Ambient -20°C "Silote GP, Rosal AB, de Souza MM, et al. Infusion of galanin into the mid-caudal portion of the dorsal raphe nucleus has an anxiolytic effect on rats in the elevated T-maze. Behav Brain Res. 2013 Sep 1;252:312-7. PMID: 23791934.

 

Echevarria DJ, Hernandez A, Diogenes A, et al. Administration of the galanin antagonist M40 into lateral septum attenuates shock probe defensive burying behavior in rats. Neuropeptides. 2005 Oct;39(5):445-51. PMID: 16084587.

 

Rada P, Avena NM, Leibowitz SF, et al. Ethanol intake is increased by injection of galanin in the paraventricular nucleus and reduced by a galanin antagonist. Alcohol. 2004 Jun;33(2):91-7. PMID: 15528006.

 

Koegler FH, York DA, Bray GA. The effects on feeding of galanin and M40 when injected into the nucleus of the solitary tract, the lateral parabrachial nucleus, and the third ventricle. Physiol Behav. 1999 Aug;67(2):259-67. PMID: 10477058.

 

Park JJ, Baum MJ. Intracerebroventricular infusion of the galanin antagonist M40 attenuates heterosexual partner preference in ferrets. Behav Neurosci. 1999 Apr;113(2):391-400. PMID: 10357463.

" Not dangerous goods.

LKT M0040 M40 1 mg 387 Peptide; galanin antagonist. 64: PN:US20050009742 PAGE: 20 claimed sequence 143896-17-7 ≥95% 1981.34 C94H145N23O24 CC(C)CC(C(=O)NC(C)C(=O)NC(CC(C)C)C(=O)NC(C)C(=O)N)NC(=O)C(C)NC(=O)C1CCCN1C(=O)C2CCCN2C(=O)C3CCCN3C(=O)CNC(=O)C(CC(C)C)NC(=O)C(CC(C)C)NC(=O)C(CC4=CC=C(C=C4)O)NC(=O)CNC(=O)C(C)NC(=O)C(CO)NC(=O)C(CC(=O)N)NC(=O)C(CC(C)C)NC(=O)C(C(C)O)NC(=O)C(CC5=CNC6=CC=CC=C65)NC(=O)CN Ambient -20°C "Silote GP, Rosal AB, de Souza MM, et al. Infusion of galanin into the mid-caudal portion of the dorsal raphe nucleus has an anxiolytic effect on rats in the elevated T-maze. Behav Brain Res. 2013 Sep 1;252:312-7. PMID: 23791934.

 

Echevarria DJ, Hernandez A, Diogenes A, et al. Administration of the galanin antagonist M40 into lateral septum attenuates shock probe defensive burying behavior in rats. Neuropeptides. 2005 Oct;39(5):445-51. PMID: 16084587.

 

Rada P, Avena NM, Leibowitz SF, et al. Ethanol intake is increased by injection of galanin in the paraventricular nucleus and reduced by a galanin antagonist. Alcohol. 2004 Jun;33(2):91-7. PMID: 15528006.

 

Koegler FH, York DA, Bray GA. The effects on feeding of galanin and M40 when injected into the nucleus of the solitary tract, the lateral parabrachial nucleus, and the third ventricle. Physiol Behav. 1999 Aug;67(2):259-67. PMID: 10477058.

 

Park JJ, Baum MJ. Intracerebroventricular infusion of the galanin antagonist M40 attenuates heterosexual partner preference in ferrets. Behav Neurosci. 1999 Apr;113(2):391-400. PMID: 10357463.

" Not dangerous goods.

LKT T0098 10-Deacetyltaxol C 5 mg 396.2 Diterpene found in Taxus; potential microtubule depolymerization inhibitor. ≥98% 805.91 C44H55NO13 Ambient -20°C Soluble in methanol, ethanol and DMSO. "Su J, Shi HX, Wang LJ, et al. Chemical constituents of bark of Taxus chinensis var. mairei. Zhong Yao Cai. 2014 Feb;37(2):243-51. PMID: 25095344.

 

McLaughlin JL, Miller RW, Powell RG, et al. 19-Hydroxybaccatin III, 10-deacetylcephalomannine, and 10-deacetyltaxol: new antitumor taxanes from Taxus wallichiana. J Nat Prod. 1981 May-Jun;44(3):312-9. PMID: 7264680.

" Not dangerous goods.

LKT M0040 M40 2.5 mg 684.1 Peptide; galanin antagonist. 64: PN:US20050009742 PAGE: 20 claimed sequence 143896-17-7 ≥95% 1981.34 C94H145N23O24 CC(C)CC(C(=O)NC(C)C(=O)NC(CC(C)C)C(=O)NC(C)C(=O)N)NC(=O)C(C)NC(=O)C1CCCN1C(=O)C2CCCN2C(=O)C3CCCN3C(=O)CNC(=O)C(CC(C)C)NC(=O)C(CC(C)C)NC(=O)C(CC4=CC=C(C=C4)O)NC(=O)CNC(=O)C(C)NC(=O)C(CO)NC(=O)C(CC(=O)N)NC(=O)C(CC(C)C)NC(=O)C(C(C)O)NC(=O)C(CC5=CNC6=CC=CC=C65)NC(=O)CN Ambient -20°C "Silote GP, Rosal AB, de Souza MM, et al. Infusion of galanin into the mid-caudal portion of the dorsal raphe nucleus has an anxiolytic effect on rats in the elevated T-maze. Behav Brain Res. 2013 Sep 1;252:312-7. PMID: 23791934.

 

Echevarria DJ, Hernandez A, Diogenes A, et al. Administration of the galanin antagonist M40 into lateral septum attenuates shock probe defensive burying behavior in rats. Neuropeptides. 2005 Oct;39(5):445-51. PMID: 16084587.

 

Rada P, Avena NM, Leibowitz SF, et al. Ethanol intake is increased by injection of galanin in the paraventricular nucleus and reduced by a galanin antagonist. Alcohol. 2004 Jun;33(2):91-7. PMID: 15528006.

 

Koegler FH, York DA, Bray GA. The effects on feeding of galanin and M40 when injected into the nucleus of the solitary tract, the lateral parabrachial nucleus, and the third ventricle. Physiol Behav. 1999 Aug;67(2):259-67. PMID: 10477058.

 

Park JJ, Baum MJ. Intracerebroventricular infusion of the galanin antagonist M40 attenuates heterosexual partner preference in ferrets. Behav Neurosci. 1999 Apr;113(2):391-400. PMID: 10357463.

" Not dangerous goods.

LKT T0098 10-Deacetyltaxol C 10 mg 633.8 Diterpene found in Taxus; potential microtubule depolymerization inhibitor. ≥98% 805.91 C44H55NO13 Ambient -20°C Soluble in methanol, ethanol and DMSO. "Su J, Shi HX, Wang LJ, et al. Chemical constituents of bark of Taxus chinensis var. mairei. Zhong Yao Cai. 2014 Feb;37(2):243-51. PMID: 25095344.

 

McLaughlin JL, Miller RW, Powell RG, et al. 19-Hydroxybaccatin III, 10-deacetylcephalomannine, and 10-deacetyltaxol: new antitumor taxanes from Taxus wallichiana. J Nat Prod. 1981 May-Jun;44(3):312-9. PMID: 7264680.

" Not dangerous goods.

LKT T0098 10-Deacetyltaxol C 25 mg 1237.6 Diterpene found in Taxus; potential microtubule depolymerization inhibitor. ≥98% 805.91 C44H55NO13 Ambient -20°C Soluble in methanol, ethanol and DMSO. "Su J, Shi HX, Wang LJ, et al. Chemical constituents of bark of Taxus chinensis var. mairei. Zhong Yao Cai. 2014 Feb;37(2):243-51. PMID: 25095344.

 

McLaughlin JL, Miller RW, Powell RG, et al. 19-Hydroxybaccatin III, 10-deacetylcephalomannine, and 10-deacetyltaxol: new antitumor taxanes from Taxus wallichiana. J Nat Prod. 1981 May-Jun;44(3):312-9. PMID: 7264680.

" Not dangerous goods.

LKT M0114 Madecassic Acid 500 mg 88.3 Triterpene originally found in Centella; (2α,3β,4α,6β)-2,3,6,23-tetrahydroxy-Urs-12-en-28-oic acid Brahmic acid 18449-41-7 ≥95% 504.7 C30H48O6 CC1CCC2(CCC3(C(=CCC4C3(CC(C5C4(CC(C(C5(C)CO)O)O)C)O)C)C2C1C)C)C(=O)O Ambient Ambient "Zhang H, Zhang M, Tao Y, et al. Madecassic acid inhibits the mouse colon cancer growth by inducing apoptosis and immunomodulation. J BUON. 2014 Apr-Jun;19(2):372-6. PMID: 24965394.

 

Won JH, Shin JS, Park HJ, et al. Anti-inflammatory effects of madecassic acid via the suppression of NF-kappaB pathway in LPS-induced RAW 264.7 macrophage cells. Planta Med. 2010 Feb;76(3):251-7. PMID: 19774506.

" Not dangerous goods.

LKT M0114 Madecassic Acid 1 g 115.5 Triterpene originally found in Centella; (2α,3β,4α,6β)-2,3,6,23-tetrahydroxy-Urs-12-en-28-oic acid Brahmic acid 18449-41-7 ≥95% 504.7 C30H48O6 CC1CCC2(CCC3(C(=CCC4C3(CC(C5C4(CC(C(C5(C)CO)O)O)C)O)C)C2C1C)C)C(=O)O Ambient Ambient "Zhang H, Zhang M, Tao Y, et al. Madecassic acid inhibits the mouse colon cancer growth by inducing apoptosis and immunomodulation. J BUON. 2014 Apr-Jun;19(2):372-6. PMID: 24965394.

 

Won JH, Shin JS, Park HJ, et al. Anti-inflammatory effects of madecassic acid via the suppression of NF-kappaB pathway in LPS-induced RAW 264.7 macrophage cells. Planta Med. 2010 Feb;76(3):251-7. PMID: 19774506.

" Not dangerous goods.

LKT M0114 Madecassic Acid 5 g 407.7 Triterpene originally found in Centella; (2α,3β,4α,6β)-2,3,6,23-tetrahydroxy-Urs-12-en-28-oic acid Brahmic acid 18449-41-7 ≥95% 504.7 C30H48O6 CC1CCC2(CCC3(C(=CCC4C3(CC(C5C4(CC(C(C5(C)CO)O)O)C)O)C)C2C1C)C)C(=O)O Ambient Ambient "Zhang H, Zhang M, Tao Y, et al. Madecassic acid inhibits the mouse colon cancer growth by inducing apoptosis and immunomodulation. J BUON. 2014 Apr-Jun;19(2):372-6. PMID: 24965394.

 

Won JH, Shin JS, Park HJ, et al. Anti-inflammatory effects of madecassic acid via the suppression of NF-kappaB pathway in LPS-induced RAW 264.7 macrophage cells. Planta Med. 2010 Feb;76(3):251-7. PMID: 19774506.

" Not dangerous goods.

LKT M0115 Magic RedTM Caspases 3 & 7 Assay Kit 25 Tests 270.3 Caspase 3 and 7 activity measuring kit. Ambient 4°C

LKT M0115 Magic RedTM Caspases 3 & 7 Assay Kit 100 Tests 747.2 Caspase 3 and 7 activity measuring kit. Ambient 4°C

LKT T0097 10-Deacetyltaxol B 5 mg 369.8 Diterpene found in Taxus; potential microtubule depolymerization inhibitor. 10-Deacetylcephalomannine 76429-85-1 ≥98% 789.86 C43H51NO13 CC=C(C)C(=O)NC(C1=CC=CC=C1)C(C(=O)OC2CC3(C(C4C(C(CC5C4(CO5)OC(=O)C)O)(C(=O)C(C(=C2C)C3(C)C)O)C)OC(=O)C6=CC=CC=C6)O)O Ambient -20°C Soluble in methanol, ethanol or DMSO. McLaughlin JL, Miller RW, Powell RG, et al. 19-Hydroxybaccatin III, 10-deacetylcephalomannine, and 10-deacetyltaxol: new antitumor taxanes from Taxus wallichiana. J Nat Prod. 1981 May-Jun;44(3):312-9. PMID: 7264680. Not dangerous goods.

LKT M0116 Magic RedTM Cathepsin B Assay Kit 25 Tests 267.4 Cathepsin B activity measuring kit. Ambient 4°C

LKT T0097 10-Deacetyltaxol B 10 mg 591.4 Diterpene found in Taxus; potential microtubule depolymerization inhibitor. 10-Deacetylcephalomannine 76429-85-1 ≥98% 789.86 C43H51NO13 CC=C(C)C(=O)NC(C1=CC=CC=C1)C(C(=O)OC2CC3(C(C4C(C(CC5C4(CO5)OC(=O)C)O)(C(=O)C(C(=C2C)C3(C)C)O)C)OC(=O)C6=CC=CC=C6)O)O Ambient -20°C Soluble in methanol, ethanol or DMSO. McLaughlin JL, Miller RW, Powell RG, et al. 19-Hydroxybaccatin III, 10-deacetylcephalomannine, and 10-deacetyltaxol: new antitumor taxanes from Taxus wallichiana. J Nat Prod. 1981 May-Jun;44(3):312-9. PMID: 7264680. Not dangerous goods.

LKT M0116 Magic RedTM Cathepsin B Assay Kit 100 Tests 747.2 Cathepsin B activity measuring kit. Ambient 4°C

LKT T0097 10-Deacetyltaxol B 25 mg 1155.2 Diterpene found in Taxus; potential microtubule depolymerization inhibitor. 10-Deacetylcephalomannine 76429-85-1 ≥98% 789.86 C43H51NO13 CC=C(C)C(=O)NC(C1=CC=CC=C1)C(C(=O)OC2CC3(C(C4C(C(CC5C4(CO5)OC(=O)C)O)(C(=O)C(C(=C2C)C3(C)C)O)C)OC(=O)C6=CC=CC=C6)O)O Ambient -20°C Soluble in methanol, ethanol or DMSO. McLaughlin JL, Miller RW, Powell RG, et al. 19-Hydroxybaccatin III, 10-deacetylcephalomannine, and 10-deacetyltaxol: new antitumor taxanes from Taxus wallichiana. J Nat Prod. 1981 May-Jun;44(3):312-9. PMID: 7264680. Not dangerous goods.

LKT M0117 Magic RedTM Cathepsin K Assay Kit 100 Tests 747.2 Cathepsin K activity measuring kit. Ambient 4°C

LKT M0117 Magic RedTM Cathepsin K Assay Kit 25 Tests 267.4 Cathepsin K activity measuring kit. Ambient 4°C

LKT M0118 Magic RedTM Cathepsin L Assay Kit 25 Tests 267.4 Cathepsin L activity measuring kit. Ambient 4°C

LKT M0118 Magic RedTM Cathepsin L Assay Kit 100 Tests 747.2 Cathepsin L activity measuring kit. Ambient 4°C

LKT M0124 Magainin 1 0.5 mg 132 Antimicrobial peptide found in frogs, induces pore formation in cell membranes. 108433-99-4 ≥95% 2409.9 C112H177N29O28S CCC(C)C(C(=O)NCC(=O)NC(CCCCN)C(=O)NC(CC1=CC=CC=C1)C(=O)NC(CC(C)C)C(=O)NC(CC2=CN=CN2)C(=O)NC(CO)C(=O)NC(C)C(=O)NCC(=O)NC(CCCCN)C(=O)NC(CC3=CC=CC=C3)C(=O)NCC(=O)NC(CCCCN)C(=O)NC(C)C(=O)NC(CC4=CC=CC=C4)C(=O)NC(C(C)C)C(=O)NCC(=O)NC(CCC(=O)O)C(=O)NC(C(C)CC)C(=O)NC(CCSC)C(=O)NC(CCCCN)C(=O)NC(CO)C(=O)O)NC(=O)CN Ambient -20°C Soluble in water or 1% acetic acid (1 mg/ml)(clear colorless solution) "Humblot V, Yala JF, Thebault P, et al. The antibacterial activity of Magainin I immobilized onto mixed thiols Self-Assembled Monolayers. Biomaterials. 2009 Jul;30(21):3503-12. PMID: 19345992.

 

Cruz-Chamorro L, Puertollano MA, Puertollano E, et al. In vitro biological activities of magainin alone or in combination with nisin. Peptides. 2006 Jun;27(6):1201-9. PMID: 16356589.

 

Mozsolits H, Wirth HJ, Werkmeister J, et al. Analysis of antimicrobial peptide interactions with hybrid bilayer membrane systems using surface plasmon resonance. Biochim Biophys Acta. 2001 May 2;1512(1):64-76. PMID: 11334625.

 

Matsuzaki K. Why and how are peptide-lipid interactions utilized for self-defense? Magainins and tachyplesins as archetypes. Biochim Biophys Acta. 1999 Dec 15;1462(1-2):1-10. PMID: 10590299.

 

Cruciani RA, Barker JL, Durell SR, et al. Magainin 2, a natural antibiotic from frog skin, forms ion channels in lipid bilayer membranes.

" Not dangerous goods.

LKT M0124 Magainin 1 1 mg 225 Antimicrobial peptide found in frogs, induces pore formation in cell membranes. 108433-99-4 ≥95% 2409.9 C112H177N29O28S CCC(C)C(C(=O)NCC(=O)NC(CCCCN)C(=O)NC(CC1=CC=CC=C1)C(=O)NC(CC(C)C)C(=O)NC(CC2=CN=CN2)C(=O)NC(CO)C(=O)NC(C)C(=O)NCC(=O)NC(CCCCN)C(=O)NC(CC3=CC=CC=C3)C(=O)NCC(=O)NC(CCCCN)C(=O)NC(C)C(=O)NC(CC4=CC=CC=C4)C(=O)NC(C(C)C)C(=O)NCC(=O)NC(CCC(=O)O)C(=O)NC(C(C)CC)C(=O)NC(CCSC)C(=O)NC(CCCCN)C(=O)NC(CO)C(=O)O)NC(=O)CN Ambient -20°C Soluble in water or 1% acetic acid (1 mg/ml)(clear colorless solution) "Humblot V, Yala JF, Thebault P, et al. The antibacterial activity of Magainin I immobilized onto mixed thiols Self-Assembled Monolayers. Biomaterials. 2009 Jul;30(21):3503-12. PMID: 19345992.

 

Cruz-Chamorro L, Puertollano MA, Puertollano E, et al. In vitro biological activities of magainin alone or in combination with nisin. Peptides. 2006 Jun;27(6):1201-9. PMID: 16356589.

 

Mozsolits H, Wirth HJ, Werkmeister J, et al. Analysis of antimicrobial peptide interactions with hybrid bilayer membrane systems using surface plasmon resonance. Biochim Biophys Acta. 2001 May 2;1512(1):64-76. PMID: 11334625.

 

Matsuzaki K. Why and how are peptide-lipid interactions utilized for self-defense? Magainins and tachyplesins as archetypes. Biochim Biophys Acta. 1999 Dec 15;1462(1-2):1-10. PMID: 10590299.

 

Cruciani RA, Barker JL, Durell SR, et al. Magainin 2, a natural antibiotic from frog skin, forms ion channels in lipid bilayer membranes.

" Not dangerous goods.

LKT M0124 Magainin 1 2.5 mg 396.1 Antimicrobial peptide found in frogs, induces pore formation in cell membranes. 108433-99-4 ≥95% 2409.9 C112H177N29O28S CCC(C)C(C(=O)NCC(=O)NC(CCCCN)C(=O)NC(CC1=CC=CC=C1)C(=O)NC(CC(C)C)C(=O)NC(CC2=CN=CN2)C(=O)NC(CO)C(=O)NC(C)C(=O)NCC(=O)NC(CCCCN)C(=O)NC(CC3=CC=CC=C3)C(=O)NCC(=O)NC(CCCCN)C(=O)NC(C)C(=O)NC(CC4=CC=CC=C4)C(=O)NC(C(C)C)C(=O)NCC(=O)NC(CCC(=O)O)C(=O)NC(C(C)CC)C(=O)NC(CCSC)C(=O)NC(CCCCN)C(=O)NC(CO)C(=O)O)NC(=O)CN Ambient -20°C Soluble in water or 1% acetic acid (1 mg/ml)(clear colorless solution) "Humblot V, Yala JF, Thebault P, et al. The antibacterial activity of Magainin I immobilized onto mixed thiols Self-Assembled Monolayers. Biomaterials. 2009 Jul;30(21):3503-12. PMID: 19345992.

 

Cruz-Chamorro L, Puertollano MA, Puertollano E, et al. In vitro biological activities of magainin alone or in combination with nisin. Peptides. 2006 Jun;27(6):1201-9. PMID: 16356589.

 

Mozsolits H, Wirth HJ, Werkmeister J, et al. Analysis of antimicrobial peptide interactions with hybrid bilayer membrane systems using surface plasmon resonance. Biochim Biophys Acta. 2001 May 2;1512(1):64-76. PMID: 11334625.

 

Matsuzaki K. Why and how are peptide-lipid interactions utilized for self-defense? Magainins and tachyplesins as archetypes. Biochim Biophys Acta. 1999 Dec 15;1462(1-2):1-10. PMID: 10590299.

 

Cruciani RA, Barker JL, Durell SR, et al. Magainin 2, a natural antibiotic from frog skin, forms ion channels in lipid bilayer membranes.

" Not dangerous goods.

LKT M0125 Magnolol 10 mg 54 Lignan found in Magnolia; GABA-A potentiator. 5,5'-Di-2-propenyl-[1,1'-biphenyl]-2,2'-diol Dehydrodichavicol 528-43-8 ≥98% 266.34 C18H18O2 C=CCC1=CC(=C(C=C1)O)C2=C(C=CC(=C2)CC=C)O Ambient 4°C Soluble in ethanol. "Wang JJ, Zhao R, Liang JC, et al. The antidiabetic and hepatoprotective effects of magnolol on diabetic rats induced by high-fat diet and streptozotocin. Yao Xue Xue Bao. 2014 Apr;49(4):476-81. PMID: 24974464.

 

Liu Y, Cao W, Zhang B, et al. The natural compound magnolol inhibits invasion and exhibits potential in human breast cancer therapy. Sci Rep. 2013 Nov 14;3:3098. PMID: 24226295.

 

Kim KM, Kim NS, Kim J, et al. Magnolol suppresses vascular endothelial growth factor-induced angiogenesis by inhibiting Ras-dependent mitogen-activated protein kinase and phosphatidylinositol 3-kinase/Akt signaling pathways. Nutr Cancer. 2013;65(8):1245-53. PMID: 24066970.

 

Li YS, Hong YF, He J, et al. Effects of magnolol on impairment of learning and memory abilities induced by scopolamine in mice. Biol Pharm Bull. 2013;36(5):764-71. PMID: 23445942.

 

Fu Y, Liu B, Zhang N, et al. Magnolol inhibits lipopolysaccharide-induced inflammatory response by interfering with TLR4 mediated NF-κB and MAPKs signaling pathways. J Ethnopharmacol. 2013 Jan 9;145(1):193-9. PMID: 23127653.

 

Kwak EJ, Lee YS, Choi EM. Effect of magnolol on the function of osteoblastic MC3T3-E1 cells. Mediators Inflamm. 2012;2012:829650. PMID: 22474400.

 

Ai J, Wang X, Nielsen M. Honokiol and magnolol selectively interact with GABAA receptor subtypes in vitro. Pharmacology. 2001 Jul;63(1):34-41. PMID: 11408830.

 

Bang KH, Kim YK, Min BS, et al. Antifungal activity of magnolol and honokiol. Arch Pharm Res. 2000 Feb;23(1):46-9. PMID: 10728656.

" N Not dangerous goods.

LKT M0125 Magnolol 25 mg 112.1 Lignan found in Magnolia; GABA-A potentiator. 5,5'-Di-2-propenyl-[1,1'-biphenyl]-2,2'-diol Dehydrodichavicol 528-43-8 ≥98% 266.34 C18H18O2 C=CCC1=CC(=C(C=C1)O)C2=C(C=CC(=C2)CC=C)O Ambient 4°C Soluble in ethanol. "Wang JJ, Zhao R, Liang JC, et al. The antidiabetic and hepatoprotective effects of magnolol on diabetic rats induced by high-fat diet and streptozotocin. Yao Xue Xue Bao. 2014 Apr;49(4):476-81. PMID: 24974464.

 

Liu Y, Cao W, Zhang B, et al. The natural compound magnolol inhibits invasion and exhibits potential in human breast cancer therapy. Sci Rep. 2013 Nov 14;3:3098. PMID: 24226295.

 

Kim KM, Kim NS, Kim J, et al. Magnolol suppresses vascular endothelial growth factor-induced angiogenesis by inhibiting Ras-dependent mitogen-activated protein kinase and phosphatidylinositol 3-kinase/Akt signaling pathways. Nutr Cancer. 2013;65(8):1245-53. PMID: 24066970.

 

Li YS, Hong YF, He J, et al. Effects of magnolol on impairment of learning and memory abilities induced by scopolamine in mice. Biol Pharm Bull. 2013;36(5):764-71. PMID: 23445942.

 

Fu Y, Liu B, Zhang N, et al. Magnolol inhibits lipopolysaccharide-induced inflammatory response by interfering with TLR4 mediated NF-κB and MAPKs signaling pathways. J Ethnopharmacol. 2013 Jan 9;145(1):193-9. PMID: 23127653.

 

Kwak EJ, Lee YS, Choi EM. Effect of magnolol on the function of osteoblastic MC3T3-E1 cells. Mediators Inflamm. 2012;2012:829650. PMID: 22474400.

 

Ai J, Wang X, Nielsen M. Honokiol and magnolol selectively interact with GABAA receptor subtypes in vitro. Pharmacology. 2001 Jul;63(1):34-41. PMID: 11408830.

 

Bang KH, Kim YK, Min BS, et al. Antifungal activity of magnolol and honokiol. Arch Pharm Res. 2000 Feb;23(1):46-9. PMID: 10728656.

" N Not dangerous goods.

LKT M0125 Magnolol 100 mg 373.7 Lignan found in Magnolia; GABA-A potentiator. 5,5'-Di-2-propenyl-[1,1'-biphenyl]-2,2'-diol Dehydrodichavicol 528-43-8 ≥98% 266.34 C18H18O2 C=CCC1=CC(=C(C=C1)O)C2=C(C=CC(=C2)CC=C)O Ambient 4°C Soluble in ethanol. "Wang JJ, Zhao R, Liang JC, et al. The antidiabetic and hepatoprotective effects of magnolol on diabetic rats induced by high-fat diet and streptozotocin. Yao Xue Xue Bao. 2014 Apr;49(4):476-81. PMID: 24974464.

 

Liu Y, Cao W, Zhang B, et al. The natural compound magnolol inhibits invasion and exhibits potential in human breast cancer therapy. Sci Rep. 2013 Nov 14;3:3098. PMID: 24226295.

 

Kim KM, Kim NS, Kim J, et al. Magnolol suppresses vascular endothelial growth factor-induced angiogenesis by inhibiting Ras-dependent mitogen-activated protein kinase and phosphatidylinositol 3-kinase/Akt signaling pathways. Nutr Cancer. 2013;65(8):1245-53. PMID: 24066970.

 

Li YS, Hong YF, He J, et al. Effects of magnolol on impairment of learning and memory abilities induced by scopolamine in mice. Biol Pharm Bull. 2013;36(5):764-71. PMID: 23445942.

 

Fu Y, Liu B, Zhang N, et al. Magnolol inhibits lipopolysaccharide-induced inflammatory response by interfering with TLR4 mediated NF-κB and MAPKs signaling pathways. J Ethnopharmacol. 2013 Jan 9;145(1):193-9. PMID: 23127653.

 

Kwak EJ, Lee YS, Choi EM. Effect of magnolol on the function of osteoblastic MC3T3-E1 cells. Mediators Inflamm. 2012;2012:829650. PMID: 22474400.

 

Ai J, Wang X, Nielsen M. Honokiol and magnolol selectively interact with GABAA receptor subtypes in vitro. Pharmacology. 2001 Jul;63(1):34-41. PMID: 11408830.

 

Bang KH, Kim YK, Min BS, et al. Antifungal activity of magnolol and honokiol. Arch Pharm Res. 2000 Feb;23(1):46-9. PMID: 10728656.

" N Not dangerous goods.

LKT T0094 2′,7-Bisacetyltaxol 5 mg 369.8 Taxane synthesis intermediate. ≥98% 937.98 C51H55NO16 Ambient -20°C Soluble in methanol, ethanol., or DMSO. "Williams HJ, Moyna G, Scott AI, et al. NMR and molecular modeling study of the conformations of taxol 2'-acetate in chloroform and aqueous dimethyl sulfoxide solutions. J Med Chem. 1996 Mar 29;39(7):1555-9. PMID: 8691488.

 

Mellado W, Magri NF, Kingston DG, et al. Preparation and biological activity of taxol acetates. Biochem Biophys Res Commun. 1984 Oct 30;124(2):329-36. PMID: 6548627.

" Not dangerous goods.

LKT T0094 2′,7-Bisacetyltaxol 10 mg 591.4 Taxane synthesis intermediate. ≥98% 937.98 C51H55NO16 Ambient -20°C Soluble in methanol, ethanol., or DMSO. "Williams HJ, Moyna G, Scott AI, et al. NMR and molecular modeling study of the conformations of taxol 2'-acetate in chloroform and aqueous dimethyl sulfoxide solutions. J Med Chem. 1996 Mar 29;39(7):1555-9. PMID: 8691488.

 

Mellado W, Magri NF, Kingston DG, et al. Preparation and biological activity of taxol acetates. Biochem Biophys Res Commun. 1984 Oct 30;124(2):329-36. PMID: 6548627.

" Not dangerous goods.

LKT T0094 2′,7-Bisacetyltaxol 25 mg 1155.2 Taxane synthesis intermediate. ≥98% 937.98 C51H55NO16 Ambient -20°C Soluble in methanol, ethanol., or DMSO. "Williams HJ, Moyna G, Scott AI, et al. NMR and molecular modeling study of the conformations of taxol 2'-acetate in chloroform and aqueous dimethyl sulfoxide solutions. J Med Chem. 1996 Mar 29;39(7):1555-9. PMID: 8691488.

 

Mellado W, Magri NF, Kingston DG, et al. Preparation and biological activity of taxol acetates. Biochem Biophys Res Commun. 1984 Oct 30;124(2):329-36. PMID: 6548627.

" Not dangerous goods.

LKT M0126 Magainin 2 0.5 mg 72.1 Antimicrobial peptide found in frogs, induces pore formation in cell membranes. Z-12 Peptide, Mag-2 108433-95-0 ≥95% 2466.95 C114H180N30O29S CCC(C)C(C(=O)NCC(=O)NC(CCCCN)C(=O)NC(CC1=CC=CC=C1)C(=O)NC(CC(C)C)C(=O)NC(CC2=CN=CN2)C(=O)NC(CO)C(=O)NC(C)C(=O)NC(CCCCN)C(=O)NC(CCCCN)C(=O)NC(CC3=CC=CC=C3)C(=O)NCC(=O)NC(CCCCN)C(=O)NC(C)C(=O)NC(CC4=CC=CC=C4)C(=O)NC(C(C)C)C(=O)NCC(=O)NC(CCC(=O)O)C(=O)NC(C(C)CC)C(=O)NC(CCSC)C(=O)NC(CC(=O)N)C(=O)NC(CO)C(=O)O)NC(=O)CN Ambient -20°C "Last NB, Miranker AD. Common mechanism unites membrane poration by amyloid and antimicrobial peptides. Proc Natl Acad Sci U S A. 2013 Apr 16;110(16):6382-7. PMID: 23576726.

 

Miyazaki Y, Aoki M, Yano Y, et al. Interaction of antimicrobial peptide magainin 2 with gangliosides as a target for human cell binding. Biochemistry. 2012 Dec 21;51(51):10229-35. PMID: 23194027.

 

Tamba Y, Ariyama H, Levadny V, et al. Kinetic pathway of antimicrobial peptide magainin 2-induced pore formation in lipid membranes. J Phys Chem B. 2010 Sep 23;114(37):12018-26. PMID: 20799752.

" Not dangerous goods.

LKT M0126 Magainin 2 1 mg 123.1 Antimicrobial peptide found in frogs, induces pore formation in cell membranes. Z-12 Peptide, Mag-2 108433-95-0 ≥95% 2466.95 C114H180N30O29S CCC(C)C(C(=O)NCC(=O)NC(CCCCN)C(=O)NC(CC1=CC=CC=C1)C(=O)NC(CC(C)C)C(=O)NC(CC2=CN=CN2)C(=O)NC(CO)C(=O)NC(C)C(=O)NC(CCCCN)C(=O)NC(CCCCN)C(=O)NC(CC3=CC=CC=C3)C(=O)NCC(=O)NC(CCCCN)C(=O)NC(C)C(=O)NC(CC4=CC=CC=C4)C(=O)NC(C(C)C)C(=O)NCC(=O)NC(CCC(=O)O)C(=O)NC(C(C)CC)C(=O)NC(CCSC)C(=O)NC(CC(=O)N)C(=O)NC(CO)C(=O)O)NC(=O)CN Ambient -20°C "Last NB, Miranker AD. Common mechanism unites membrane poration by amyloid and antimicrobial peptides. Proc Natl Acad Sci U S A. 2013 Apr 16;110(16):6382-7. PMID: 23576726.

 

Miyazaki Y, Aoki M, Yano Y, et al. Interaction of antimicrobial peptide magainin 2 with gangliosides as a target for human cell binding. Biochemistry. 2012 Dec 21;51(51):10229-35. PMID: 23194027.

 

Tamba Y, Ariyama H, Levadny V, et al. Kinetic pathway of antimicrobial peptide magainin 2-induced pore formation in lipid membranes. J Phys Chem B. 2010 Sep 23;114(37):12018-26. PMID: 20799752.

" Not dangerous goods.

LKT M0126 Magainin 2 2.5 mg 216.1 Antimicrobial peptide found in frogs, induces pore formation in cell membranes. Z-12 Peptide, Mag-2 108433-95-0 ≥95% 2466.95 C114H180N30O29S CCC(C)C(C(=O)NCC(=O)NC(CCCCN)C(=O)NC(CC1=CC=CC=C1)C(=O)NC(CC(C)C)C(=O)NC(CC2=CN=CN2)C(=O)NC(CO)C(=O)NC(C)C(=O)NC(CCCCN)C(=O)NC(CCCCN)C(=O)NC(CC3=CC=CC=C3)C(=O)NCC(=O)NC(CCCCN)C(=O)NC(C)C(=O)NC(CC4=CC=CC=C4)C(=O)NC(C(C)C)C(=O)NCC(=O)NC(CCC(=O)O)C(=O)NC(C(C)CC)C(=O)NC(CCSC)C(=O)NC(CC(=O)N)C(=O)NC(CO)C(=O)O)NC(=O)CN Ambient -20°C "Last NB, Miranker AD. Common mechanism unites membrane poration by amyloid and antimicrobial peptides. Proc Natl Acad Sci U S A. 2013 Apr 16;110(16):6382-7. PMID: 23576726.

 

Miyazaki Y, Aoki M, Yano Y, et al. Interaction of antimicrobial peptide magainin 2 with gangliosides as a target for human cell binding. Biochemistry. 2012 Dec 21;51(51):10229-35. PMID: 23194027.

 

Tamba Y, Ariyama H, Levadny V, et al. Kinetic pathway of antimicrobial peptide magainin 2-induced pore formation in lipid membranes. J Phys Chem B. 2010 Sep 23;114(37):12018-26. PMID: 20799752.

" Not dangerous goods.

LKT T0093 2′-Acetyltaxol 5 mg 381.3 Taxane synthesis intermediate. Benzenepropanoic acid, α-(acetyloxy)-β- (benzoyl- amino)-,6,12b-bis(acetyloxy)-12-(benzoyloxy)- 2a,3,4,4a,5,6,9,10,11,12,12a,12b-dodecahydro-4,11- dihydroxy-4a,8,13,13-tetramethyl-5-oxo-7,11-methano-1H-cyclodeca(3,4)benz(1,2-b)oxet-9-yl ester, (2aR) Taxol 2'-acetate 92950-40-8 ≥98% 895.95 C49H53NO15 CC1=C2C(C(=O)C3(C(CC4C(C3C(C(C2(C)C)(CC1OC(=O)C(C(C5=CC=CC=C5)NC(=O)C6=CC=CC=C6)OC(=O)C)O)OC(=O)C7=CC=CC=C7)(CO4)OC(=O)C)O)C)OC(=O)C Ambient -20°C "Williams HJ, Moyna G, Scott AI, et al. NMR and molecular modeling study of the conformations of taxol 2'-acetate in chloroform and aqueous dimethyl sulfoxide solutions. J Med Chem. 1996 Mar 29;39(7):1555-9. PMID: 8691488.

 

Mellado W, Magri NF, Kingston DG, et al. Preparation and biological activity of taxol acetates. Biochem Biophys Res Commun. 1984 Oct 30;124(2):329-36. PMID: 6548627.

" Not dangerous goods.

LKT T0093 2′-Acetyltaxol 10 mg 591.4 Taxane synthesis intermediate. Benzenepropanoic acid, α-(acetyloxy)-β- (benzoyl- amino)-,6,12b-bis(acetyloxy)-12-(benzoyloxy)- 2a,3,4,4a,5,6,9,10,11,12,12a,12b-dodecahydro-4,11- dihydroxy-4a,8,13,13-tetramethyl-5-oxo-7,11-methano-1H-cyclodeca(3,4)benz(1,2-b)oxet-9-yl ester, (2aR) Taxol 2'-acetate 92950-40-8 ≥98% 895.95 C49H53NO15 CC1=C2C(C(=O)C3(C(CC4C(C3C(C(C2(C)C)(CC1OC(=O)C(C(C5=CC=CC=C5)NC(=O)C6=CC=CC=C6)OC(=O)C)O)OC(=O)C7=CC=CC=C7)(CO4)OC(=O)C)O)C)OC(=O)C Ambient -20°C "Williams HJ, Moyna G, Scott AI, et al. NMR and molecular modeling study of the conformations of taxol 2'-acetate in chloroform and aqueous dimethyl sulfoxide solutions. J Med Chem. 1996 Mar 29;39(7):1555-9. PMID: 8691488.

 

Mellado W, Magri NF, Kingston DG, et al. Preparation and biological activity of taxol acetates. Biochem Biophys Res Commun. 1984 Oct 30;124(2):329-36. PMID: 6548627.

" Not dangerous goods.

LKT M0144 Malantide 1 mg 60 PKA substrate. 86555-35-3 ≥95% 1633.93 C72H124N22O21 CCC(C)C(C(=O)O)NC(=O)C(CCCCN)NC(=O)C(CC(C)C)NC(=O)C1CCCN1C(=O)C(CCC(=O)O)NC(=O)C(CC2=CC=C(C=C2)O)NC(=O)C(C(C)C)NC(=O)C(CO)NC(=O)CNC(=O)C(CO)NC(=O)C(CCCN=C(N)N)NC(=O)C(CCCCN)NC(=O)C(C(C)O)NC(=O)C(CCCN=C(N)N)N Ambient -20°C "de Boer AR, Letzel T, Lingeman H, et al. Systematic development of an enzymatic phosphorylation assay compatible with mass spectrometric detection. Anal Bioanal Chem. 2005 Feb;381(3):647-55. PMID: 15703914.

 

Murray KJ, England PJ, Lynham JA, et al. Use of a synthetic dodecapeptide (malantide) to measure the cyclic AMP-dependent protein kinase activity ratio in a variety of tissues. Biochem J. 1990 May 1;267(3):703-8. PMID: 2160235.

"

LKT M0144 Malantide 2 mg 101.9 PKA substrate. 86555-35-3 ≥95% 1633.93 C72H124N22O21 CCC(C)C(C(=O)O)NC(=O)C(CCCCN)NC(=O)C(CC(C)C)NC(=O)C1CCCN1C(=O)C(CCC(=O)O)NC(=O)C(CC2=CC=C(C=C2)O)NC(=O)C(C(C)C)NC(=O)C(CO)NC(=O)CNC(=O)C(CO)NC(=O)C(CCCN=C(N)N)NC(=O)C(CCCCN)NC(=O)C(C(C)O)NC(=O)C(CCCN=C(N)N)N Ambient -20°C "de Boer AR, Letzel T, Lingeman H, et al. Systematic development of an enzymatic phosphorylation assay compatible with mass spectrometric detection. Anal Bioanal Chem. 2005 Feb;381(3):647-55. PMID: 15703914.

 

Murray KJ, England PJ, Lynham JA, et al. Use of a synthetic dodecapeptide (malantide) to measure the cyclic AMP-dependent protein kinase activity ratio in a variety of tissues. Biochem J. 1990 May 1;267(3):703-8. PMID: 2160235.

"

LKT T0093 2′-Acetyltaxol 25 mg 1155.2 Taxane synthesis intermediate. Benzenepropanoic acid, α-(acetyloxy)-β- (benzoyl- amino)-,6,12b-bis(acetyloxy)-12-(benzoyloxy)- 2a,3,4,4a,5,6,9,10,11,12,12a,12b-dodecahydro-4,11- dihydroxy-4a,8,13,13-tetramethyl-5-oxo-7,11-methano-1H-cyclodeca(3,4)benz(1,2-b)oxet-9-yl ester, (2aR) Taxol 2'-acetate 92950-40-8 ≥98% 895.95 C49H53NO15 CC1=C2C(C(=O)C3(C(CC4C(C3C(C(C2(C)C)(CC1OC(=O)C(C(C5=CC=CC=C5)NC(=O)C6=CC=CC=C6)OC(=O)C)O)OC(=O)C7=CC=CC=C7)(CO4)OC(=O)C)O)C)OC(=O)C Ambient -20°C "Williams HJ, Moyna G, Scott AI, et al. NMR and molecular modeling study of the conformations of taxol 2'-acetate in chloroform and aqueous dimethyl sulfoxide solutions. J Med Chem. 1996 Mar 29;39(7):1555-9. PMID: 8691488.

 

Mellado W, Magri NF, Kingston DG, et al. Preparation and biological activity of taxol acetates. Biochem Biophys Res Commun. 1984 Oct 30;124(2):329-36. PMID: 6548627.

" Not dangerous goods.

LKT M0144 Malantide 5 mg 180 PKA substrate. 86555-35-3 ≥95% 1633.93 C72H124N22O21 CCC(C)C(C(=O)O)NC(=O)C(CCCCN)NC(=O)C(CC(C)C)NC(=O)C1CCCN1C(=O)C(CCC(=O)O)NC(=O)C(CC2=CC=C(C=C2)O)NC(=O)C(C(C)C)NC(=O)C(CO)NC(=O)CNC(=O)C(CO)NC(=O)C(CCCN=C(N)N)NC(=O)C(CCCCN)NC(=O)C(C(C)O)NC(=O)C(CCCN=C(N)N)N Ambient -20°C "de Boer AR, Letzel T, Lingeman H, et al. Systematic development of an enzymatic phosphorylation assay compatible with mass spectrometric detection. Anal Bioanal Chem. 2005 Feb;381(3):647-55. PMID: 15703914.

 

Murray KJ, England PJ, Lynham JA, et al. Use of a synthetic dodecapeptide (malantide) to measure the cyclic AMP-dependent protein kinase activity ratio in a variety of tissues. Biochem J. 1990 May 1;267(3):703-8. PMID: 2160235.

"

LKT T0092 1-Hydroxybaccatin I 5 mg 265.8 Diterpene found in Taxus; potential microtubule depolymerization inhibitor. ≥98% 652.68 C32H44O14 Ambient -20°C "Chao Z, Tan M, Paudel MK, et al. Development of an indirect competitive enzyme-linked immunosorbent assay (icELISA) using highly specific monoclonal antibody against paclitaxel. J Nat Med. 2013 Jul;67(3):512-8. PMID: 23007175.

 

Mao S, Chen W, Liao S. Studies on chemical constituents of the stem bark of Taxus cuspidata. Zhong Yao Cai. 1999 Jul;22(7):346-7. PMID: 12571929.

" Not dangerous goods.

LKT T0092 1-Hydroxybaccatin I 10 mg 462.1 Diterpene found in Taxus; potential microtubule depolymerization inhibitor. ≥98% 652.68 C32H44O14 Ambient -20°C "Chao Z, Tan M, Paudel MK, et al. Development of an indirect competitive enzyme-linked immunosorbent assay (icELISA) using highly specific monoclonal antibody against paclitaxel. J Nat Med. 2013 Jul;67(3):512-8. PMID: 23007175.

 

Mao S, Chen W, Liao S. Studies on chemical constituents of the stem bark of Taxus cuspidata. Zhong Yao Cai. 1999 Jul;22(7):346-7. PMID: 12571929.

" Not dangerous goods.

LKT T0092 1-Hydroxybaccatin I 25 mg 990.2 Diterpene found in Taxus; potential microtubule depolymerization inhibitor. ≥98% 652.68 C32H44O14 Ambient -20°C "Chao Z, Tan M, Paudel MK, et al. Development of an indirect competitive enzyme-linked immunosorbent assay (icELISA) using highly specific monoclonal antibody against paclitaxel. J Nat Med. 2013 Jul;67(3):512-8. PMID: 23007175.

 

Mao S, Chen W, Liao S. Studies on chemical constituents of the stem bark of Taxus cuspidata. Zhong Yao Cai. 1999 Jul;22(7):346-7. PMID: 12571929.

" Not dangerous goods.

LKT M0172 Mastoparan 1 mg 270.2 Antimicrobial peptide found in Vespula lewisii, mast cell degranulation stimulator; GTPase potentiator. "Mast cell degranulating peptide (Vespula lewisii) 

" 72093-21-1 ≥95% 1478.92 C70H131N19O15 CCC(C)C(C(=O)NC(CC(=O)N)C(=O)NC(CC(C)C)C(=O)NC(CCCCN)C(=O)NC(C)C(=O)NC(CC(C)C)C(=O)NC(C)C(=O)NC(C)C(=O)NC(CC(C)C)C(=O)NC(C)C(=O)NC(CCCCN)C(=O)NC(CCCCN)C(=O)NC(C(C)CC)C(=O)NC(CC(C)C)C(=O)N)N Ambient -20°C Soluble in CH3COOH (1mg/mL). "Brophy TM, Coller BS, Ahamed J. Identification of the thiol isomerase-binding peptide, mastoparan, as a novel inhibitor of shear-induced transforming growth factor β1 (TGF-β1) activation. J Biol Chem. 2013 Apr 12;288(15):10628-39. PMID: 23463512.

 

Nakao S, Komagoe K, Inoue T, et al. Comparative study of the membrane-permeabilizing activities of mastoparans and related histamine-releasing agents in bacteria, erythrocytes, and mast cells. Biochim Biophys Acta. 2011 Jan;1808(1):490-7. PMID: 20955685.

 

Higashijima T, Uzu S, Nakajima T, et al. Mastoparan, a peptide toxin from wasp venom, mimics receptors by activating GTP-binding regulatory proteins (G proteins). J Biol Chem. 1988 May 15;263(14):6491-4. PMID: 3129426.

" Not dangerous goods.

LKT M0173 Mastoparan X 1 mg 72.1 Antimicrobial peptide found in bee and wasp venom; Gα GPCR agonist Mast cell degranulating peptide (Vespa xanthoptera) (9CI) 72093-22-2 ≥95% 1556.01 C73H126N20O15S CCC(C)C(C(=O)NC(CC(=O)N)C(=O)NC(CC1=CNC2=CC=CC=C21)C(=O)NC(CCCCN)C(=O)NCC(=O)NC(C(C)CC)C(=O)NC(C)C(=O)NC(C)C(=O)NC(CCSC)C(=O)NC(C)C(=O)NC(CCCCN)C(=O)NC(CCCCN)C(=O)NC(CC(C)C)C(=O)NC(CC(C)C)C(=O)N)N Ambient -20°C "dos Santos LD, Aparecido dos Santos Pinto JR, Menegasso AR, et al. Proteomic profiling of the molecular targets of interactions of the mastoparan peptide Protopolybia MP-III at the level of endosomal membranes from rat mast cells. Proteomics. 2012 Aug;12(17):2682-93. PMID: 22761183.

 

Cabrera MP, Alvares DS, Leite NB, et al. New insight into the mechanism of action of wasp mastoparan peptides: lytic activity and clustering observed with giant vesicles. Langmuir. 2011 Sep 6;27(17):10805-13. PMID: 21797216.

 

Etzerodt T, Henriksen JR, Rasmussen P, et al. Selective acylation enhances membrane charge sensitivity of the antimicrobial peptide mastoparan-x. Biophys J. 2011 Jan 19;100(2):399-409. PMID: 21244836.

 

Todokoro Y, Yumen I, Fukushima K, et al. Structure of tightly membrane-bound mastoparan-X, a G-protein-activating peptide, determined by solid-state NMR. Biophys J. 2006 Aug 15;91(4):1368-79. PMID: 16714348.

" Not dangerous goods.

LKT M0173 Mastoparan X 2 mg 123.1 Antimicrobial peptide found in bee and wasp venom; Gα GPCR agonist Mast cell degranulating peptide (Vespa xanthoptera) (9CI) 72093-22-2 ≥95% 1556.01 C73H126N20O15S CCC(C)C(C(=O)NC(CC(=O)N)C(=O)NC(CC1=CNC2=CC=CC=C21)C(=O)NC(CCCCN)C(=O)NCC(=O)NC(C(C)CC)C(=O)NC(C)C(=O)NC(C)C(=O)NC(CCSC)C(=O)NC(C)C(=O)NC(CCCCN)C(=O)NC(CCCCN)C(=O)NC(CC(C)C)C(=O)NC(CC(C)C)C(=O)N)N Ambient -20°C "dos Santos LD, Aparecido dos Santos Pinto JR, Menegasso AR, et al. Proteomic profiling of the molecular targets of interactions of the mastoparan peptide Protopolybia MP-III at the level of endosomal membranes from rat mast cells. Proteomics. 2012 Aug;12(17):2682-93. PMID: 22761183.

 

Cabrera MP, Alvares DS, Leite NB, et al. New insight into the mechanism of action of wasp mastoparan peptides: lytic activity and clustering observed with giant vesicles. Langmuir. 2011 Sep 6;27(17):10805-13. PMID: 21797216.

 

Etzerodt T, Henriksen JR, Rasmussen P, et al. Selective acylation enhances membrane charge sensitivity of the antimicrobial peptide mastoparan-x. Biophys J. 2011 Jan 19;100(2):399-409. PMID: 21244836.

 

Todokoro Y, Yumen I, Fukushima K, et al. Structure of tightly membrane-bound mastoparan-X, a G-protein-activating peptide, determined by solid-state NMR. Biophys J. 2006 Aug 15;91(4):1368-79. PMID: 16714348.

" Not dangerous goods.

LKT M0173 Mastoparan X 5 mg 216.1 Antimicrobial peptide found in bee and wasp venom; Gα GPCR agonist Mast cell degranulating peptide (Vespa xanthoptera) (9CI) 72093-22-2 ≥95% 1556.01 C73H126N20O15S CCC(C)C(C(=O)NC(CC(=O)N)C(=O)NC(CC1=CNC2=CC=CC=C21)C(=O)NC(CCCCN)C(=O)NCC(=O)NC(C(C)CC)C(=O)NC(C)C(=O)NC(C)C(=O)NC(CCSC)C(=O)NC(C)C(=O)NC(CCCCN)C(=O)NC(CCCCN)C(=O)NC(CC(C)C)C(=O)NC(CC(C)C)C(=O)N)N Ambient -20°C "dos Santos LD, Aparecido dos Santos Pinto JR, Menegasso AR, et al. Proteomic profiling of the molecular targets of interactions of the mastoparan peptide Protopolybia MP-III at the level of endosomal membranes from rat mast cells. Proteomics. 2012 Aug;12(17):2682-93. PMID: 22761183.

 

Cabrera MP, Alvares DS, Leite NB, et al. New insight into the mechanism of action of wasp mastoparan peptides: lytic activity and clustering observed with giant vesicles. Langmuir. 2011 Sep 6;27(17):10805-13. PMID: 21797216.

 

Etzerodt T, Henriksen JR, Rasmussen P, et al. Selective acylation enhances membrane charge sensitivity of the antimicrobial peptide mastoparan-x. Biophys J. 2011 Jan 19;100(2):399-409. PMID: 21244836.

 

Todokoro Y, Yumen I, Fukushima K, et al. Structure of tightly membrane-bound mastoparan-X, a G-protein-activating peptide, determined by solid-state NMR. Biophys J. 2006 Aug 15;91(4):1368-79. PMID: 16714348.

" Not dangerous goods.

LKT M0224 Melanoma Antigen Gene-encoding Fragment 3 (271-279), human 1 mg 72.1 Peptide antigen produced by hepatocellular carcinoma cells. MAGE-3 160295-81-8 ≥95% 1058.3 C53H79N13O10 Ambient -20°C "Zhou M, Peng JR, Zhang HG, et al. Identification of two naturally presented MAGE antigenic peptides from a patient with hepatocellular carcinoma by mass spectrometry. Immunol Lett. 2005 Jun 15;99(1):113-21. PMID: 15885805.

 

Zerbini A, Pilli M, Soliani P, et al. Ex vivo characterization of tumor-derived melanoma antigen encoding gene-specific CD8+cells in patients with hepatocellular carcinoma. J Hepatol. 2004 Jan;40(1):102-9. PMID: 14672620.

 

Kanaoka S, Yamasaki S, Okino T, et al. Induction of human leukocyte antigen (HLA)-A2-restricted and MAGE-3-gene-derived peptide-specific cytolytic T lymphocytes using cultured dendritic cells from an HLA-A2 esophageal cancer patient. J Surg Oncol. 1999 May;71(1):16-21. PMID: 10362086.

"

LKT M0224 Melanoma Antigen Gene-encoding Fragment 3 (271-279), human 2 mg 123.1 Peptide antigen produced by hepatocellular carcinoma cells. MAGE-3 160295-81-8 ≥95% 1058.3 C53H79N13O10 Ambient -20°C "Zhou M, Peng JR, Zhang HG, et al. Identification of two naturally presented MAGE antigenic peptides from a patient with hepatocellular carcinoma by mass spectrometry. Immunol Lett. 2005 Jun 15;99(1):113-21. PMID: 15885805.

 

Zerbini A, Pilli M, Soliani P, et al. Ex vivo characterization of tumor-derived melanoma antigen encoding gene-specific CD8+cells in patients with hepatocellular carcinoma. J Hepatol. 2004 Jan;40(1):102-9. PMID: 14672620.

 

Kanaoka S, Yamasaki S, Okino T, et al. Induction of human leukocyte antigen (HLA)-A2-restricted and MAGE-3-gene-derived peptide-specific cytolytic T lymphocytes using cultured dendritic cells from an HLA-A2 esophageal cancer patient. J Surg Oncol. 1999 May;71(1):16-21. PMID: 10362086.

"

LKT M0224 Melanoma Antigen Gene-encoding Fragment 3 (271-279), human 5 mg 216.1 Peptide antigen produced by hepatocellular carcinoma cells. MAGE-3 160295-81-8 ≥95% 1058.3 C53H79N13O10 Ambient -20°C "Zhou M, Peng JR, Zhang HG, et al. Identification of two naturally presented MAGE antigenic peptides from a patient with hepatocellular carcinoma by mass spectrometry. Immunol Lett. 2005 Jun 15;99(1):113-21. PMID: 15885805.

 

Zerbini A, Pilli M, Soliani P, et al. Ex vivo characterization of tumor-derived melanoma antigen encoding gene-specific CD8+cells in patients with hepatocellular carcinoma. J Hepatol. 2004 Jan;40(1):102-9. PMID: 14672620.

 

Kanaoka S, Yamasaki S, Okino T, et al. Induction of human leukocyte antigen (HLA)-A2-restricted and MAGE-3-gene-derived peptide-specific cytolytic T lymphocytes using cultured dendritic cells from an HLA-A2 esophageal cancer patient. J Surg Oncol. 1999 May;71(1):16-21. PMID: 10362086.

"

LKT M0248 Manidipine Dihydrochloride 25 mg 75 Dihydropyridine; L-type and T-type Ca2+ channel blocker. 89226-75-5 ≥98% 683.62 C35H38N4O6 2HCl CC1=C(C(C(=C(N1)C)C(=O)OCCN2CCN(CC2)C(C3=CC=CC=C3)C4=CC=CC=C4)C5=CC(=CC=C5)[N+](=O)[O-])C(=O)OC.Cl.Cl Ambient Ambient "Costa S, Zimetti F, Pedrelli M, et al. Manidipine reduces pro-inflammatory cytokines secretion in human endothelial cells and macrophages. Pharmacol Res. 2010 Sep;62(3):265-70. PMID: 20347984.

 

Hayashi K, Ozawa Y, Fujiwara K, et al. Role of actions of calcium antagonists on efferent arterioles--with special references to glomerular hypertension. Am J Nephrol. 2003 Jul-Aug;23(4):229-44. PMID: 12840599.

 

Onuki T. Effects of a calcium channel blocker, manidipine hydrochloride, on the regulatory mechanism of glomerular capillary pressure in SHR. Nihon Jinzo Gakkai Shi. 1995 Feb;37(2):119-26. PMID: 7752503.

 

" "UN number: 2811     Class: 6.1     Packing Group: III

Proper shipping name: Toxic solid, organic, n.o.s. (Manidipine dihydrochloride)"

LKT M0248 Manidipine Dihydrochloride 100 mg 187.4 Dihydropyridine; L-type and T-type Ca2+ channel blocker. 89226-75-5 ≥98% 683.62 C35H38N4O6 2HCl CC1=C(C(C(=C(N1)C)C(=O)OCCN2CCN(CC2)C(C3=CC=CC=C3)C4=CC=CC=C4)C5=CC(=CC=C5)[N+](=O)[O-])C(=O)OC.Cl.Cl Ambient Ambient "Costa S, Zimetti F, Pedrelli M, et al. Manidipine reduces pro-inflammatory cytokines secretion in human endothelial cells and macrophages. Pharmacol Res. 2010 Sep;62(3):265-70. PMID: 20347984.

 

Hayashi K, Ozawa Y, Fujiwara K, et al. Role of actions of calcium antagonists on efferent arterioles--with special references to glomerular hypertension. Am J Nephrol. 2003 Jul-Aug;23(4):229-44. PMID: 12840599.

 

Onuki T. Effects of a calcium channel blocker, manidipine hydrochloride, on the regulatory mechanism of glomerular capillary pressure in SHR. Nihon Jinzo Gakkai Shi. 1995 Feb;37(2):119-26. PMID: 7752503.

 

" "UN number: 2811     Class: 6.1     Packing Group: III

Proper shipping name: Toxic solid, organic, n.o.s. (Manidipine dihydrochloride)"

LKT M0248 Manidipine Dihydrochloride 250 mg 346.9 Dihydropyridine; L-type and T-type Ca2+ channel blocker. 89226-75-5 ≥98% 683.62 C35H38N4O6 2HCl CC1=C(C(C(=C(N1)C)C(=O)OCCN2CCN(CC2)C(C3=CC=CC=C3)C4=CC=CC=C4)C5=CC(=CC=C5)[N+](=O)[O-])C(=O)OC.Cl.Cl Ambient Ambient "Costa S, Zimetti F, Pedrelli M, et al. Manidipine reduces pro-inflammatory cytokines secretion in human endothelial cells and macrophages. Pharmacol Res. 2010 Sep;62(3):265-70. PMID: 20347984.

 

Hayashi K, Ozawa Y, Fujiwara K, et al. Role of actions of calcium antagonists on efferent arterioles--with special references to glomerular hypertension. Am J Nephrol. 2003 Jul-Aug;23(4):229-44. PMID: 12840599.

 

Onuki T. Effects of a calcium channel blocker, manidipine hydrochloride, on the regulatory mechanism of glomerular capillary pressure in SHR. Nihon Jinzo Gakkai Shi. 1995 Feb;37(2):119-26. PMID: 7752503.

 

" "UN number: 2811     Class: 6.1     Packing Group: III

Proper shipping name: Toxic solid, organic, n.o.s. (Manidipine dihydrochloride)"

LKT M0262 Maprotiline Hydrochloride 1 g 40.7 Tetracycline; FIASMA, histamine H1, 5-HT2, mAChR, α1-adrenergic antagonist, L-type Ca2+ channel blocker, NET inhibitor. N-Methyl-9.10-ethanoanthracene-9(10H)-propanamine hydrochloride Deprilept; Ludiomil; Psymion 10347-81-6 ≥98% 313.87 C20H23N HCl CNCCCC12CCC(C3=CC=CC=C31)C4=CC=CC=C24.Cl Ambient Ambient Soluble in methanol and chloroform. Slightly soluble in water. "Jan CR, Su JA, Teng CC, et al. Mechanism of maprotiline-induced apoptosis: role of [Ca2+](i), ERK, JNK and caspase-3 signaling pathways. Toxicology. 2013 Feb 8;304:1-12. PMID: 23219590.

 

Zahradník I, Minarovic I, Zahradníková A. Inhibition of the cardiac L-type calcium channel current by antidepressant drugs. J Pharmacol Exp Ther. 2008 Mar;324(3):977-84. PMID: 18048694.

 

Mayers AG, Baldwin DS. Antidepressants and their effect on sleep. Hum Psychopharmacol. 2005 Dec;20(8):533-59. PMID: 16229049.

 

Muscat R, Papp M, Willner P. Reversal of stress-induced anhedonia by the atypical antidepressants, fluoxetine and maprotiline. Psychopharmacology (Berl). 1992;109(4):433-8. PMID: 1365858.

" Xn Not dangerous goods.

LKT M0262 Maprotiline Hydrochloride 5 g 163.2 Tetracycline; FIASMA, histamine H1, 5-HT2, mAChR, α1-adrenergic antagonist, L-type Ca2+ channel blocker, NET inhibitor. N-Methyl-9.10-ethanoanthracene-9(10H)-propanamine hydrochloride Deprilept; Ludiomil; Psymion 10347-81-6 ≥98% 313.87 C20H23N HCl CNCCCC12CCC(C3=CC=CC=C31)C4=CC=CC=C24.Cl Ambient Ambient Soluble in methanol and chloroform. Slightly soluble in water. "Jan CR, Su JA, Teng CC, et al. Mechanism of maprotiline-induced apoptosis: role of [Ca2+](i), ERK, JNK and caspase-3 signaling pathways. Toxicology. 2013 Feb 8;304:1-12. PMID: 23219590.

 

Zahradník I, Minarovic I, Zahradníková A. Inhibition of the cardiac L-type calcium channel current by antidepressant drugs. J Pharmacol Exp Ther. 2008 Mar;324(3):977-84. PMID: 18048694.

 

Mayers AG, Baldwin DS. Antidepressants and their effect on sleep. Hum Psychopharmacol. 2005 Dec;20(8):533-59. PMID: 16229049.

 

Muscat R, Papp M, Willner P. Reversal of stress-induced anhedonia by the atypical antidepressants, fluoxetine and maprotiline. Psychopharmacology (Berl). 1992;109(4):433-8. PMID: 1365858.

" Xn Not dangerous goods.

LKT M0272 Mastoparan 7 1 mg 60 Antimicrobial peptide found in bee and wasp venom; Gi/o GPCR agonist, PLA2 activator. Mas7 145854-59-7 ≥95% 1421.85 C67H124N18O15 CCC(C)C(C(=O)NC(CC(=O)N)C(=O)NC(CC(C)C)C(=O)NC(CCCCN)C(=O)NC(C)C(=O)NC(CC(C)C)C(=O)NC(C)C(=O)NC(C)C(=O)NC(CC(C)C)C(=O)NC(C)C(=O)NC(CCCCN)C(=O)NC(C)C(=O)NC(CC(C)C)C(=O)NC(CC(C)C)C(=O)N)N Ambient -20°C "Zhang P, Ray R, Singh BR, et al. Mastoparan-7 rescues botulinum toxin-A poisoned neurons in a mouse spinal cord cell culture model. Toxicon. 2013 Dec 15;76:37-43. PMID: 24047963.

 

Sprague RS, Bowles EA, Achilleus D, et al. A selective phosphodiesterase 3 inhibitor rescues low PO2-induced ATP release from erythrocytes of humans with type 2 diabetes: implication for vascular control. Am J Physiol Heart Circ Physiol. 2011 Dec;301(6):H2466-72. Erratum in: Am J Physiol Heart Circ Physiol. 2012 Jan;302(1):H378. PMID: 21963837.

 

Sprague R, Bowles E, Stumpf M, et al. Rabbit erythrocytes possess adenylyl cyclase type II that is activated by the heterotrimeric G proteins Gs and Gi. Pharmacol Rep. 2005;57 Suppl:222-8. PMID: 16415502.

 

Bensimon M, Chang AI, de Bold ML, et al. Participation of G proteins in natriuretic peptide hormone secretion from heart atria. Endocrinology. 2004 Nov;145(11):5313-21. PMID: 15308619.

" Not dangerous goods.

LKT M0272 Mastoparan 7 2 mg 101.9 Antimicrobial peptide found in bee and wasp venom; Gi/o GPCR agonist, PLA2 activator. Mas7 145854-59-7 ≥95% 1421.85 C67H124N18O15 CCC(C)C(C(=O)NC(CC(=O)N)C(=O)NC(CC(C)C)C(=O)NC(CCCCN)C(=O)NC(C)C(=O)NC(CC(C)C)C(=O)NC(C)C(=O)NC(C)C(=O)NC(CC(C)C)C(=O)NC(C)C(=O)NC(CCCCN)C(=O)NC(C)C(=O)NC(CC(C)C)C(=O)NC(CC(C)C)C(=O)N)N Ambient -20°C "Zhang P, Ray R, Singh BR, et al. Mastoparan-7 rescues botulinum toxin-A poisoned neurons in a mouse spinal cord cell culture model. Toxicon. 2013 Dec 15;76:37-43. PMID: 24047963.

 

Sprague RS, Bowles EA, Achilleus D, et al. A selective phosphodiesterase 3 inhibitor rescues low PO2-induced ATP release from erythrocytes of humans with type 2 diabetes: implication for vascular control. Am J Physiol Heart Circ Physiol. 2011 Dec;301(6):H2466-72. Erratum in: Am J Physiol Heart Circ Physiol. 2012 Jan;302(1):H378. PMID: 21963837.

 

Sprague R, Bowles E, Stumpf M, et al. Rabbit erythrocytes possess adenylyl cyclase type II that is activated by the heterotrimeric G proteins Gs and Gi. Pharmacol Rep. 2005;57 Suppl:222-8. PMID: 16415502.

 

Bensimon M, Chang AI, de Bold ML, et al. Participation of G proteins in natriuretic peptide hormone secretion from heart atria. Endocrinology. 2004 Nov;145(11):5313-21. PMID: 15308619.

" Not dangerous goods.

LKT M0272 Mastoparan 7 5 mg 180 Antimicrobial peptide found in bee and wasp venom; Gi/o GPCR agonist, PLA2 activator. Mas7 145854-59-7 ≥95% 1421.85 C67H124N18O15 CCC(C)C(C(=O)NC(CC(=O)N)C(=O)NC(CC(C)C)C(=O)NC(CCCCN)C(=O)NC(C)C(=O)NC(CC(C)C)C(=O)NC(C)C(=O)NC(C)C(=O)NC(CC(C)C)C(=O)NC(C)C(=O)NC(CCCCN)C(=O)NC(C)C(=O)NC(CC(C)C)C(=O)NC(CC(C)C)C(=O)N)N Ambient -20°C "Zhang P, Ray R, Singh BR, et al. Mastoparan-7 rescues botulinum toxin-A poisoned neurons in a mouse spinal cord cell culture model. Toxicon. 2013 Dec 15;76:37-43. PMID: 24047963.

 

Sprague RS, Bowles EA, Achilleus D, et al. A selective phosphodiesterase 3 inhibitor rescues low PO2-induced ATP release from erythrocytes of humans with type 2 diabetes: implication for vascular control. Am J Physiol Heart Circ Physiol. 2011 Dec;301(6):H2466-72. Erratum in: Am J Physiol Heart Circ Physiol. 2012 Jan;302(1):H378. PMID: 21963837.

 

Sprague R, Bowles E, Stumpf M, et al. Rabbit erythrocytes possess adenylyl cyclase type II that is activated by the heterotrimeric G proteins Gs and Gi. Pharmacol Rep. 2005;57 Suppl:222-8. PMID: 16415502.

 

Bensimon M, Chang AI, de Bold ML, et al. Participation of G proteins in natriuretic peptide hormone secretion from heart atria. Endocrinology. 2004 Nov;145(11):5313-21. PMID: 15308619.

" Not dangerous goods.

LKT T0091 7-(Triethylsilyl)-10-deacetylbaccatin III 5 mg 396.2 Taxol derivative. ≥97% 658.85 C35H50O10Si Ambient -20°C "Krawczyk E, Luczak M, Kniotek M, et al. Cytotoxic, antiviral (in-vitro and in-vivo), immunomodulatory activity and influence on mitotic divisions of three taxol derivatives: 10-deacetyl-baccatin III, methyl (N-benzoyl-(2'R,3'S)-3'-phenylisoserinate) and N-benzoyl-(2'R,3'S)-3'-phenylisoserine. J Pharm Pharmacol. 2005 Jun;57(6):791-7. PMID: 15969936.

 

Samaranayake G, Neidigh KA, Kingston DG. Modified taxols, 8. Deacylation and reacylation of baccatin III. J Nat Prod. 1993 Jun;56(6):884-98. PMID: 8102392.

" Not dangerous goods.

LKT T0091 7-(Triethylsilyl)-10-deacetylbaccatin III 10 mg 633.8 Taxol derivative. ≥97% 658.85 C35H50O10Si Ambient -20°C "Krawczyk E, Luczak M, Kniotek M, et al. Cytotoxic, antiviral (in-vitro and in-vivo), immunomodulatory activity and influence on mitotic divisions of three taxol derivatives: 10-deacetyl-baccatin III, methyl (N-benzoyl-(2'R,3'S)-3'-phenylisoserinate) and N-benzoyl-(2'R,3'S)-3'-phenylisoserine. J Pharm Pharmacol. 2005 Jun;57(6):791-7. PMID: 15969936.

 

Samaranayake G, Neidigh KA, Kingston DG. Modified taxols, 8. Deacylation and reacylation of baccatin III. J Nat Prod. 1993 Jun;56(6):884-98. PMID: 8102392.

" Not dangerous goods.

LKT M0273 Mastoparan 8 0.5 mg 60 Antimicrobial peptide found in bee and wasp venom; Gi/o GPCR agonist. Mas8 ≥95% 1506.96 C70H131N21O15 Ambient -20°C "dos Santos LD, Aparecido dos Santos Pinto JR, Menegasso AR, et al. Proteomic profiling of the molecular targets of interactions of the mastoparan peptide Protopolybia MP-III at the level of endosomal membranes from rat mast cells. Proteomics. 2012 Aug;12(17):2682-93. PMID: 22761183.

 

Cabrera MP, Alvares DS, Leite NB, et al. New insight into the mechanism of action of wasp mastoparan peptides: lytic activity and clustering observed with giant vesicles. Langmuir. 2011 Sep 6;27(17):10805-13. PMID: 21797216.

 

Etzerodt T, Henriksen JR, Rasmussen P, et al. Selective acylation enhances membrane charge sensitivity of the antimicrobial peptide mastoparan-x. Biophys J. 2011 Jan 19;100(2):399-409. PMID: 21244836.

 

Todokoro Y, Yumen I, Fukushima K, et al. Structure of tightly membrane-bound mastoparan-X, a G-protein-activating peptide, determined by solid-state NMR. Biophys J. 2006 Aug 15;91(4):1368-79. PMID: 16714348.

 

Amin RH, Chen HQ, Veluthakal R, et al. Mastoparan-induced insulin secretion from insulin-secreting betaTC3 and INS-1 cells: evidence for its regulation by Rho subfamily of G proteins. Endocrinology. 2003 Oct;144(10):4508-18. PMID: 12960065.

 

Armstead WM. Protein kinase C activation generates superoxide and contributes to impairment of cerebrovasodilation induced by G protein activation after brain injury. Brain Res. 2003 May 9;971(2):153-60. PMID: 12706231.

 

Kowluru A. Identification and characterization of a novel protein histidine kinase in the islet beta cell: evidence for its regulation by mastoparan, an activator of G-proteins and insulin secretion. Biochem Pharmacol. 2002 Jun 15;63(12):2091-100. PMID: 12110368.

" Not dangerous goods.

LKT M0273 Mastoparan 8 1 mg 101.9 Antimicrobial peptide found in bee and wasp venom; Gi/o GPCR agonist. Mas8 ≥95% 1506.96 C70H131N21O15 Ambient -20°C "dos Santos LD, Aparecido dos Santos Pinto JR, Menegasso AR, et al. Proteomic profiling of the molecular targets of interactions of the mastoparan peptide Protopolybia MP-III at the level of endosomal membranes from rat mast cells. Proteomics. 2012 Aug;12(17):2682-93. PMID: 22761183.

 

Cabrera MP, Alvares DS, Leite NB, et al. New insight into the mechanism of action of wasp mastoparan peptides: lytic activity and clustering observed with giant vesicles. Langmuir. 2011 Sep 6;27(17):10805-13. PMID: 21797216.

 

Etzerodt T, Henriksen JR, Rasmussen P, et al. Selective acylation enhances membrane charge sensitivity of the antimicrobial peptide mastoparan-x. Biophys J. 2011 Jan 19;100(2):399-409. PMID: 21244836.

 

Todokoro Y, Yumen I, Fukushima K, et al. Structure of tightly membrane-bound mastoparan-X, a G-protein-activating peptide, determined by solid-state NMR. Biophys J. 2006 Aug 15;91(4):1368-79. PMID: 16714348.

 

Amin RH, Chen HQ, Veluthakal R, et al. Mastoparan-induced insulin secretion from insulin-secreting betaTC3 and INS-1 cells: evidence for its regulation by Rho subfamily of G proteins. Endocrinology. 2003 Oct;144(10):4508-18. PMID: 12960065.

 

Armstead WM. Protein kinase C activation generates superoxide and contributes to impairment of cerebrovasodilation induced by G protein activation after brain injury. Brain Res. 2003 May 9;971(2):153-60. PMID: 12706231.

 

Kowluru A. Identification and characterization of a novel protein histidine kinase in the islet beta cell: evidence for its regulation by mastoparan, an activator of G-proteins and insulin secretion. Biochem Pharmacol. 2002 Jun 15;63(12):2091-100. PMID: 12110368.

" Not dangerous goods.

LKT M0273 Mastoparan 8 2.5 mg 180 Antimicrobial peptide found in bee and wasp venom; Gi/o GPCR agonist. Mas8 ≥95% 1506.96 C70H131N21O15 Ambient -20°C "dos Santos LD, Aparecido dos Santos Pinto JR, Menegasso AR, et al. Proteomic profiling of the molecular targets of interactions of the mastoparan peptide Protopolybia MP-III at the level of endosomal membranes from rat mast cells. Proteomics. 2012 Aug;12(17):2682-93. PMID: 22761183.

 

Cabrera MP, Alvares DS, Leite NB, et al. New insight into the mechanism of action of wasp mastoparan peptides: lytic activity and clustering observed with giant vesicles. Langmuir. 2011 Sep 6;27(17):10805-13. PMID: 21797216.

 

Etzerodt T, Henriksen JR, Rasmussen P, et al. Selective acylation enhances membrane charge sensitivity of the antimicrobial peptide mastoparan-x. Biophys J. 2011 Jan 19;100(2):399-409. PMID: 21244836.

 

Todokoro Y, Yumen I, Fukushima K, et al. Structure of tightly membrane-bound mastoparan-X, a G-protein-activating peptide, determined by solid-state NMR. Biophys J. 2006 Aug 15;91(4):1368-79. PMID: 16714348.

 

Amin RH, Chen HQ, Veluthakal R, et al. Mastoparan-induced insulin secretion from insulin-secreting betaTC3 and INS-1 cells: evidence for its regulation by Rho subfamily of G proteins. Endocrinology. 2003 Oct;144(10):4508-18. PMID: 12960065.

 

Armstead WM. Protein kinase C activation generates superoxide and contributes to impairment of cerebrovasodilation induced by G protein activation after brain injury. Brain Res. 2003 May 9;971(2):153-60. PMID: 12706231.

 

Kowluru A. Identification and characterization of a novel protein histidine kinase in the islet beta cell: evidence for its regulation by mastoparan, an activator of G-proteins and insulin secretion. Biochem Pharmacol. 2002 Jun 15;63(12):2091-100. PMID: 12110368.

" Not dangerous goods.

LKT T0091 7-(Triethylsilyl)-10-deacetylbaccatin III 25 mg 1237.6 Taxol derivative. ≥97% 658.85 C35H50O10Si Ambient -20°C "Krawczyk E, Luczak M, Kniotek M, et al. Cytotoxic, antiviral (in-vitro and in-vivo), immunomodulatory activity and influence on mitotic divisions of three taxol derivatives: 10-deacetyl-baccatin III, methyl (N-benzoyl-(2'R,3'S)-3'-phenylisoserinate) and N-benzoyl-(2'R,3'S)-3'-phenylisoserine. J Pharm Pharmacol. 2005 Jun;57(6):791-7. PMID: 15969936.

 

Samaranayake G, Neidigh KA, Kingston DG. Modified taxols, 8. Deacylation and reacylation of baccatin III. J Nat Prod. 1993 Jun;56(6):884-98. PMID: 8102392.

" Not dangerous goods.

LKT M0275 Mastoparan 17 1 mg 60 Peptide, inactive mastoparan analog used to measure mastoparan activity. Mas17 145854-61-1 ≥95% 1493.96 C70H132N20O15 CCC(C)C(C(=O)NC(CC(=O)N)C(=O)NC(CC(C)C)C(=O)NC(CCCCN)C(=O)NC(C)C(=O)NC(CCCCN)C(=O)NC(C)C(=O)NC(C)C(=O)NC(CC(C)C)C(=O)NC(C)C(=O)NC(CCCCN)C(=O)NC(CCCCN)C(=O)NC(CC(C)C)C(=O)NC(CC(C)C)C(=O)N)N Ambient -20°C "Amin RH, Chen HQ, Veluthakal R, et al. Mastoparan-induced insulin secretion from insulin-secreting betaTC3 and INS-1 cells: evidence for its regulation by Rho subfamily of G proteins. Endocrinology. 2003 Oct;144(10):4508-18. PMID: 12960065.

 

Armstead WM. Protein kinase C activation generates superoxide and contributes to impairment of cerebrovasodilation induced by G protein activation after brain injury. Brain Res. 2003 May 9;971(2):153-60. PMID: 12706231.

 

Kowluru A. Identification and characterization of a novel protein histidine kinase in the islet beta cell: evidence for its regulation by mastoparan, an activator of G-proteins and insulin secretion. Biochem Pharmacol. 2002 Jun 15;63(12):2091-100. PMID: 12110368.

" Not dangerous goods.

LKT M0275 Mastoparan 17 2 mg 101.9 Peptide, inactive mastoparan analog used to measure mastoparan activity. Mas17 145854-61-1 ≥95% 1493.96 C70H132N20O15 CCC(C)C(C(=O)NC(CC(=O)N)C(=O)NC(CC(C)C)C(=O)NC(CCCCN)C(=O)NC(C)C(=O)NC(CCCCN)C(=O)NC(C)C(=O)NC(C)C(=O)NC(CC(C)C)C(=O)NC(C)C(=O)NC(CCCCN)C(=O)NC(CCCCN)C(=O)NC(CC(C)C)C(=O)NC(CC(C)C)C(=O)N)N Ambient -20°C "Amin RH, Chen HQ, Veluthakal R, et al. Mastoparan-induced insulin secretion from insulin-secreting betaTC3 and INS-1 cells: evidence for its regulation by Rho subfamily of G proteins. Endocrinology. 2003 Oct;144(10):4508-18. PMID: 12960065.

 

Armstead WM. Protein kinase C activation generates superoxide and contributes to impairment of cerebrovasodilation induced by G protein activation after brain injury. Brain Res. 2003 May 9;971(2):153-60. PMID: 12706231.

 

Kowluru A. Identification and characterization of a novel protein histidine kinase in the islet beta cell: evidence for its regulation by mastoparan, an activator of G-proteins and insulin secretion. Biochem Pharmacol. 2002 Jun 15;63(12):2091-100. PMID: 12110368.

" Not dangerous goods.

LKT M0275 Mastoparan 17 5 mg 180 Peptide, inactive mastoparan analog used to measure mastoparan activity. Mas17 145854-61-1 ≥95% 1493.96 C70H132N20O15 CCC(C)C(C(=O)NC(CC(=O)N)C(=O)NC(CC(C)C)C(=O)NC(CCCCN)C(=O)NC(C)C(=O)NC(CCCCN)C(=O)NC(C)C(=O)NC(C)C(=O)NC(CC(C)C)C(=O)NC(C)C(=O)NC(CCCCN)C(=O)NC(CCCCN)C(=O)NC(CC(C)C)C(=O)NC(CC(C)C)C(=O)N)N Ambient -20°C "Amin RH, Chen HQ, Veluthakal R, et al. Mastoparan-induced insulin secretion from insulin-secreting betaTC3 and INS-1 cells: evidence for its regulation by Rho subfamily of G proteins. Endocrinology. 2003 Oct;144(10):4508-18. PMID: 12960065.

 

Armstead WM. Protein kinase C activation generates superoxide and contributes to impairment of cerebrovasodilation induced by G protein activation after brain injury. Brain Res. 2003 May 9;971(2):153-60. PMID: 12706231.

 

Kowluru A. Identification and characterization of a novel protein histidine kinase in the islet beta cell: evidence for its regulation by mastoparan, an activator of G-proteins and insulin secretion. Biochem Pharmacol. 2002 Jun 15;63(12):2091-100. PMID: 12110368.

" Not dangerous goods.

LKT T0090 7-(Triethylsilyl)-baccatin III 5 mg 396.2 Synthetic taxol synthesis intermediate; microtubule depolymerization inhibitor. 115437-21-3 ≥98% 700.89 C37H52O11Si CC[Si](CC)(CC)OC1CC2C(CO2)(C3C1(C(=O)C(C4=C(C(CC(C3OC(=O)C5=CC=CC=C5)(C4(C)C)O)O)C)OC(=O)C)C)OC(=O)C Ambient -20°C "Chakravarthi BV, Sujay R, Kuriakose GC, et al. Inhibition of cancer cell proliferation and apoptosis-inducing activity of fungal taxol and its precursor baccatin III purified from endophytic Fusarium solani. Cancer Cell Int. 2013 Oct 23;13(1):105. PMID: 24152585.

 

Lee YH, Lee YR, Kim KH, et al. Baccatin III, a synthetic precursor of taxol, enhances MHC-restricted antigen presentation in dendritic cells. Int Immunopharmacol. 2011 Aug;11(8):985-91. PMID: 21354357.

 

Ge H, Spletstoser JT, Yang Y, et al. Synthesis of docetaxel and butitaxel analogues through kinetic resolution of racemic beta-lactams with 7-O-triethylsilylbaccatin III. J Org Chem. 2007 Feb 2;72(3):756-9. PMID: 17253791.

 

Chatterjee SK, Barron DM, Vos S, et al. Baccatin III induces assembly of purified tubulin into long microtubules. Biochemistry. 2001 Jun 12;40(23):6964-70. PMID: 11389612.

" Not dangerous goods.

LKT T0090 7-(Triethylsilyl)-baccatin III 10 mg 633.8 Synthetic taxol synthesis intermediate; microtubule depolymerization inhibitor. 115437-21-3 ≥98% 700.89 C37H52O11Si CC[Si](CC)(CC)OC1CC2C(CO2)(C3C1(C(=O)C(C4=C(C(CC(C3OC(=O)C5=CC=CC=C5)(C4(C)C)O)O)C)OC(=O)C)C)OC(=O)C Ambient -20°C "Chakravarthi BV, Sujay R, Kuriakose GC, et al. Inhibition of cancer cell proliferation and apoptosis-inducing activity of fungal taxol and its precursor baccatin III purified from endophytic Fusarium solani. Cancer Cell Int. 2013 Oct 23;13(1):105. PMID: 24152585.

 

Lee YH, Lee YR, Kim KH, et al. Baccatin III, a synthetic precursor of taxol, enhances MHC-restricted antigen presentation in dendritic cells. Int Immunopharmacol. 2011 Aug;11(8):985-91. PMID: 21354357.

 

Ge H, Spletstoser JT, Yang Y, et al. Synthesis of docetaxel and butitaxel analogues through kinetic resolution of racemic beta-lactams with 7-O-triethylsilylbaccatin III. J Org Chem. 2007 Feb 2;72(3):756-9. PMID: 17253791.

 

Chatterjee SK, Barron DM, Vos S, et al. Baccatin III induces assembly of purified tubulin into long microtubules. Biochemistry. 2001 Jun 12;40(23):6964-70. PMID: 11389612.

" Not dangerous goods.

LKT M0278 Matrine 100 mg 163.2 Alkaloid found in Sophora. Matridin-15-one Sophocarpidine 519-02-8 ≥98% 248.37 C15H24N2O C1CC2C3CCCN4C3C(CCC4)CN2C(=O)C1 "Store in a cool, dry place.  Keep away from

direct, strong light." Ambient 4°C Soluble in water, benzene, chloroform, ether, and carbon disulfide. "Kan QC, Zhang S, Xu YM, et al. Matrine regulates glutamate-related excitotoxic factors in experimental autoimmune encephalomyelitis. Neurosci Lett. 2014 Feb 7;560:92-7. PMID: 24368216.

 

Xiang J, Jiang Y. Antiepileptic potential of matrine via regulation the levels of gamma-aminobutyric acid and glutamic acid in the brain. Int J Mol Sci. 2013 Dec 5;14(12):23751-61. PMID: 24317434.

 

Ma X, Chen R, Liu X, et al. Effects of matrine on JAK-STAT signaling transduction pathways in bleomycin-induced pulmonary fibrosis. Afr J Tradit Complement Altern Med. 2013 Apr 12;10(3):442-8. PMID: 24146473.

 

Zhang Y, Zhang H, Yu P, et al. Effects of matrine against the growth of human lung cancer and hepatoma cells as well as lung cancer cell migration. Cytotechnology. 2009 Apr;59(3):191-200. PMID: 19649719.

 

Ma L, Wen S, Zhan Y, et al. Anticancer effects of the Chinese medicine matrine on murine hepatocellular carcinoma cells. Planta Med. 2008 Feb;74(3):245-51. PMID: 18283616.

 

Xiao P, Kubo H, Ohsawa M, et al. kappa-Opioid receptor-mediated antinociceptive effects of stereoisomers and derivatives of (+)-matrine in mice. Planta Med. 1999 Apr;65(3):230-3. PMID: 10232067.

" Xn Not dangerous goods.

LKT T0090 7-(Triethylsilyl)-baccatin III 25 mg 1237.6 Synthetic taxol synthesis intermediate; microtubule depolymerization inhibitor. 115437-21-3 ≥98% 700.89 C37H52O11Si CC[Si](CC)(CC)OC1CC2C(CO2)(C3C1(C(=O)C(C4=C(C(CC(C3OC(=O)C5=CC=CC=C5)(C4(C)C)O)O)C)OC(=O)C)C)OC(=O)C Ambient -20°C "Chakravarthi BV, Sujay R, Kuriakose GC, et al. Inhibition of cancer cell proliferation and apoptosis-inducing activity of fungal taxol and its precursor baccatin III purified from endophytic Fusarium solani. Cancer Cell Int. 2013 Oct 23;13(1):105. PMID: 24152585.

 

Lee YH, Lee YR, Kim KH, et al. Baccatin III, a synthetic precursor of taxol, enhances MHC-restricted antigen presentation in dendritic cells. Int Immunopharmacol. 2011 Aug;11(8):985-91. PMID: 21354357.

 

Ge H, Spletstoser JT, Yang Y, et al. Synthesis of docetaxel and butitaxel analogues through kinetic resolution of racemic beta-lactams with 7-O-triethylsilylbaccatin III. J Org Chem. 2007 Feb 2;72(3):756-9. PMID: 17253791.

 

Chatterjee SK, Barron DM, Vos S, et al. Baccatin III induces assembly of purified tubulin into long microtubules. Biochemistry. 2001 Jun 12;40(23):6964-70. PMID: 11389612.

" Not dangerous goods.

LKT M0278 Matrine 500 mg 516.4 Alkaloid found in Sophora. Matridin-15-one Sophocarpidine 519-02-8 ≥98% 248.37 C15H24N2O C1CC2C3CCCN4C3C(CCC4)CN2C(=O)C1 "Store in a cool, dry place.  Keep away from

direct, strong light." Ambient 4°C Soluble in water, benzene, chloroform, ether, and carbon disulfide. "Kan QC, Zhang S, Xu YM, et al. Matrine regulates glutamate-related excitotoxic factors in experimental autoimmune encephalomyelitis. Neurosci Lett. 2014 Feb 7;560:92-7. PMID: 24368216.

 

Xiang J, Jiang Y. Antiepileptic potential of matrine via regulation the levels of gamma-aminobutyric acid and glutamic acid in the brain. Int J Mol Sci. 2013 Dec 5;14(12):23751-61. PMID: 24317434.

 

Ma X, Chen R, Liu X, et al. Effects of matrine on JAK-STAT signaling transduction pathways in bleomycin-induced pulmonary fibrosis. Afr J Tradit Complement Altern Med. 2013 Apr 12;10(3):442-8. PMID: 24146473.

 

Zhang Y, Zhang H, Yu P, et al. Effects of matrine against the growth of human lung cancer and hepatoma cells as well as lung cancer cell migration. Cytotechnology. 2009 Apr;59(3):191-200. PMID: 19649719.

 

Ma L, Wen S, Zhan Y, et al. Anticancer effects of the Chinese medicine matrine on murine hepatocellular carcinoma cells. Planta Med. 2008 Feb;74(3):245-51. PMID: 18283616.

 

Xiao P, Kubo H, Ohsawa M, et al. kappa-Opioid receptor-mediated antinociceptive effects of stereoisomers and derivatives of (+)-matrine in mice. Planta Med. 1999 Apr;65(3):230-3. PMID: 10232067.

" Xn Not dangerous goods.

LKT M0278 Matrine 1 g 883.3 Alkaloid found in Sophora. Matridin-15-one Sophocarpidine 519-02-8 ≥98% 248.37 C15H24N2O C1CC2C3CCCN4C3C(CCC4)CN2C(=O)C1 "Store in a cool, dry place.  Keep away from

direct, strong light." Ambient 4°C Soluble in water, benzene, chloroform, ether, and carbon disulfide. "Kan QC, Zhang S, Xu YM, et al. Matrine regulates glutamate-related excitotoxic factors in experimental autoimmune encephalomyelitis. Neurosci Lett. 2014 Feb 7;560:92-7. PMID: 24368216.

 

Xiang J, Jiang Y. Antiepileptic potential of matrine via regulation the levels of gamma-aminobutyric acid and glutamic acid in the brain. Int J Mol Sci. 2013 Dec 5;14(12):23751-61. PMID: 24317434.

 

Ma X, Chen R, Liu X, et al. Effects of matrine on JAK-STAT signaling transduction pathways in bleomycin-induced pulmonary fibrosis. Afr J Tradit Complement Altern Med. 2013 Apr 12;10(3):442-8. PMID: 24146473.

 

Zhang Y, Zhang H, Yu P, et al. Effects of matrine against the growth of human lung cancer and hepatoma cells as well as lung cancer cell migration. Cytotechnology. 2009 Apr;59(3):191-200. PMID: 19649719.

 

Ma L, Wen S, Zhan Y, et al. Anticancer effects of the Chinese medicine matrine on murine hepatocellular carcinoma cells. Planta Med. 2008 Feb;74(3):245-51. PMID: 18283616.

 

Xiao P, Kubo H, Ohsawa M, et al. kappa-Opioid receptor-mediated antinociceptive effects of stereoisomers and derivatives of (+)-matrine in mice. Planta Med. 1999 Apr;65(3):230-3. PMID: 10232067.

" Xn Not dangerous goods.

LKT T0081 Taurine 50 g 45.3 Endogenous sulfonic acid involved in Ca2+ signaling and cardiovascular function; GABA-A and GlyR agonist. 2-Aminoethanesulfonic acid Tauphon; β-Aminoethylsulfonic acid 107-35-7 ≥98% 125.14 C2H7NO3S C(CS(=O)(=O)O)N Ambient Ambient Soluble in 15.5 parts of water (12oC), 100 parts of 95% alc (17oC). "El Idrissi A, Okeke E, Yan X, et al. Taurine regulation of blood pressure and vasoactivity. Adv Exp Med Biol. 2013;775:407-25. PMID: 23392950.

 

Choi MJ, Kim JH, Chang KJ. The effect of dietary taurine supplementation on plasma and liver lipid concentrations and free amino acid concentrations in rats fed a high-cholesterol diet. Adv Exp Med Biol. 2006;583:235-42. PMID: 17153607.

 

Bouckenooghe T, Remacle C, Reusens B. Is taurine a functional nutrient? Curr Opin Clin Nutr Metab Care. 2006 Nov;9(6):728-33. PMID: 17053427.

 

Kong WX, Chen SW, Li YL, et al. Effects of taurine on rat behaviors in three anxiety models. Pharmacol Biochem Behav. 2006 Feb;83(2):271-6. PMID: 16540157.

 

Kerai MD, Waterfield CJ, Kenyon SH, et al. Taurine: protective properties against ethanol-induced hepatic steatosis and lipid peroxidation during chronic ethanol consumption in rats. Amino Acids. 1998;15(1-2):53-76. PMID: 9871487.

 

Huxtable RJ. Physiological actions of taurine. Physiol Rev. 1992 Jan;72(1):101-63. PMID: 1731369.

" Xi Not dangerous goods.

LKT T0081 Taurine 100 g 64.7 Endogenous sulfonic acid involved in Ca2+ signaling and cardiovascular function; GABA-A and GlyR agonist. 2-Aminoethanesulfonic acid Tauphon; β-Aminoethylsulfonic acid 107-35-7 ≥98% 125.14 C2H7NO3S C(CS(=O)(=O)O)N Ambient Ambient Soluble in 15.5 parts of water (12oC), 100 parts of 95% alc (17oC). "El Idrissi A, Okeke E, Yan X, et al. Taurine regulation of blood pressure and vasoactivity. Adv Exp Med Biol. 2013;775:407-25. PMID: 23392950.

 

Choi MJ, Kim JH, Chang KJ. The effect of dietary taurine supplementation on plasma and liver lipid concentrations and free amino acid concentrations in rats fed a high-cholesterol diet. Adv Exp Med Biol. 2006;583:235-42. PMID: 17153607.

 

Bouckenooghe T, Remacle C, Reusens B. Is taurine a functional nutrient? Curr Opin Clin Nutr Metab Care. 2006 Nov;9(6):728-33. PMID: 17053427.

 

Kong WX, Chen SW, Li YL, et al. Effects of taurine on rat behaviors in three anxiety models. Pharmacol Biochem Behav. 2006 Feb;83(2):271-6. PMID: 16540157.

 

Kerai MD, Waterfield CJ, Kenyon SH, et al. Taurine: protective properties against ethanol-induced hepatic steatosis and lipid peroxidation during chronic ethanol consumption in rats. Amino Acids. 1998;15(1-2):53-76. PMID: 9871487.

 

Huxtable RJ. Physiological actions of taurine. Physiol Rev. 1992 Jan;72(1):101-63. PMID: 1731369.

" Xi Not dangerous goods.

LKT M0368 Marbofloxacin 250 mg 89.9 Fluoroquinolone; bacterial DNA gyrase inhibitor. 9-Fluoro-2,3-dihydro-3-methyl-10-(4-methyl-piperazino)-7-oxo-7H-pyrido[1,2,3-ij][1,2,4]benzoxadiazine-6-carboxylic acid Zeniquin 115550-35-1 ≥98% 362.36 C17H19FN4O4 Ambient Ambient "Damte D, Lee SJ, Yohannes SB, et al. Comparative activities of selected fluoroquinolones against dynamic populations of Actinobacillus pleuropneumoniae in an in vitro model of time-kill continuous culture experiment. Int J Antimicrob Agents. 2013 Dec;42(6):544-52. PMID: 24139884.

 

Illambas J, Potter T, Cheng Z, et al. Pharmacodynamics of marbofloxacin for calf pneumonia pathogens. Res Vet Sci. 2013 Jun;94(3):675-81. PMID: 23375665.

 

Awji EG, Tassew DD, Lee JS, et al. Comparative mutant prevention concentration and mechanism of resistance to veterinary fluoroquinolones in Staphylococcus pseudintermedius. Vet Dermatol. 2012 Aug;23(4):376-80, e68-9. PMID: 22409306.

 

Gebru E, Choi MJ, Lee SJ, et al. Mutant-prevention concentration and mechanism of resistance in clinical isolates and enrofloxacin/marbofloxacin-selected mutants of Escherichia coli of canine origin. J Med Microbiol. 2011 Oct;60(Pt 10):1512-22. PMID: 21596912.

 

Spreng M, Deleforge J, Thomas V, et al. Antibacterial activity of marbofloxacin. A new fluoroquinolone for veterinary use against canine and feline isolates. J Vet Pharmacol Ther. 1995 Aug;18(4):284-9. PMID: 8583541.

" Not dangerous goods.

LKT M0368 Marbofloxacin 1 g 288.8 Fluoroquinolone; bacterial DNA gyrase inhibitor. 9-Fluoro-2,3-dihydro-3-methyl-10-(4-methyl-piperazino)-7-oxo-7H-pyrido[1,2,3-ij][1,2,4]benzoxadiazine-6-carboxylic acid Zeniquin 115550-35-1 ≥98% 362.36 C17H19FN4O4 Ambient Ambient "Damte D, Lee SJ, Yohannes SB, et al. Comparative activities of selected fluoroquinolones against dynamic populations of Actinobacillus pleuropneumoniae in an in vitro model of time-kill continuous culture experiment. Int J Antimicrob Agents. 2013 Dec;42(6):544-52. PMID: 24139884.

 

Illambas J, Potter T, Cheng Z, et al. Pharmacodynamics of marbofloxacin for calf pneumonia pathogens. Res Vet Sci. 2013 Jun;94(3):675-81. PMID: 23375665.

 

Awji EG, Tassew DD, Lee JS, et al. Comparative mutant prevention concentration and mechanism of resistance to veterinary fluoroquinolones in Staphylococcus pseudintermedius. Vet Dermatol. 2012 Aug;23(4):376-80, e68-9. PMID: 22409306.

 

Gebru E, Choi MJ, Lee SJ, et al. Mutant-prevention concentration and mechanism of resistance in clinical isolates and enrofloxacin/marbofloxacin-selected mutants of Escherichia coli of canine origin. J Med Microbiol. 2011 Oct;60(Pt 10):1512-22. PMID: 21596912.

 

Spreng M, Deleforge J, Thomas V, et al. Antibacterial activity of marbofloxacin. A new fluoroquinolone for veterinary use against canine and feline isolates. J Vet Pharmacol Ther. 1995 Aug;18(4):284-9. PMID: 8583541.

" Not dangerous goods.

LKT T0077 Transactivator of Transcription Peptide (2-4) 0.5 mg 90.1 Peptide, contains two cell-penetrating sequences of HIV-1 TAT protein. TAT 2-4, TAT peptide, YGRKKRRQRRRGYGRKKRRQRRRG ≥95% 3215.81 C132H240N66O29 Ambient -20°C "Hargus NJ, Thayer SA. Human immunodeficiency virus-1 Tat protein increases the number of inhibitory synapses between hippocampal neurons in culture. J Neurosci. 2013 Nov 6;33(45):17908-20. PMID: 24198379.

 

Bethel-Brown C, Yao H, Callen S, et al. HIV-1 Tat-mediated induction of platelet-derived growth factor in astrocytes: role of early growth response gene 1. J Immunol. 2011 Apr 1;186(7):4119-29. PMID: 21368226.

 

Lu SM, Tremblay MÈ, King IL, et al. HIV-1 Tat-induced microgliosis and synaptic damage via interactions between peripheral and central myeloid cells. PLoS One. 2011;6(9):e23915. PMID: 21912650.

" Not dangerous goods.

LKT T0077 Transactivator of Transcription Peptide (2-4) 1 mg 153.7 Peptide, contains two cell-penetrating sequences of HIV-1 TAT protein. TAT 2-4, TAT peptide, YGRKKRRQRRRGYGRKKRRQRRRG ≥95% 3215.81 C132H240N66O29 Ambient -20°C "Hargus NJ, Thayer SA. Human immunodeficiency virus-1 Tat protein increases the number of inhibitory synapses between hippocampal neurons in culture. J Neurosci. 2013 Nov 6;33(45):17908-20. PMID: 24198379.

 

Bethel-Brown C, Yao H, Callen S, et al. HIV-1 Tat-mediated induction of platelet-derived growth factor in astrocytes: role of early growth response gene 1. J Immunol. 2011 Apr 1;186(7):4119-29. PMID: 21368226.

 

Lu SM, Tremblay MÈ, King IL, et al. HIV-1 Tat-induced microgliosis and synaptic damage via interactions between peripheral and central myeloid cells. PLoS One. 2011;6(9):e23915. PMID: 21912650.

" Not dangerous goods.

LKT T0077 Transactivator of Transcription Peptide (2-4) 2.5 mg 270.2 Peptide, contains two cell-penetrating sequences of HIV-1 TAT protein. TAT 2-4, TAT peptide, YGRKKRRQRRRGYGRKKRRQRRRG ≥95% 3215.81 C132H240N66O29 Ambient -20°C "Hargus NJ, Thayer SA. Human immunodeficiency virus-1 Tat protein increases the number of inhibitory synapses between hippocampal neurons in culture. J Neurosci. 2013 Nov 6;33(45):17908-20. PMID: 24198379.

 

Bethel-Brown C, Yao H, Callen S, et al. HIV-1 Tat-mediated induction of platelet-derived growth factor in astrocytes: role of early growth response gene 1. J Immunol. 2011 Apr 1;186(7):4119-29. PMID: 21368226.

 

Lu SM, Tremblay MÈ, King IL, et al. HIV-1 Tat-induced microgliosis and synaptic damage via interactions between peripheral and central myeloid cells. PLoS One. 2011;6(9):e23915. PMID: 21912650.

" Not dangerous goods.

LKT T0076 Transactivator of Transcription Peptide 0.5 mg 107.8 Peptide, cell-penetrating fragment of HIV-1 TAT protein. TAT, TAT peptide, YGRKKRRQRRR ≥95% 1558.88 C64H119N33O13 Ambient -20°C "Hargus NJ, Thayer SA. Human immunodeficiency virus-1 Tat protein increases the number of inhibitory synapses between hippocampal neurons in culture. J Neurosci. 2013 Nov 6;33(45):17908-20. PMID: 24198379.

 

Bethel-Brown C, Yao H, Callen S, et al. HIV-1 Tat-mediated induction of platelet-derived growth factor in astrocytes: role of early growth response gene 1. J Immunol. 2011 Apr 1;186(7):4119-29. PMID: 21368226.

 

Lu SM, Tremblay MÈ, King IL, et al. HIV-1 Tat-induced microgliosis and synaptic damage via interactions between peripheral and central myeloid cells. PLoS One. 2011;6(9):e23915. PMID: 21912650.

" Not dangerous goods.

LKT T0076 Transactivator of Transcription Peptide 1 mg 183 Peptide, cell-penetrating fragment of HIV-1 TAT protein. TAT, TAT peptide, YGRKKRRQRRR ≥95% 1558.88 C64H119N33O13 Ambient -20°C "Hargus NJ, Thayer SA. Human immunodeficiency virus-1 Tat protein increases the number of inhibitory synapses between hippocampal neurons in culture. J Neurosci. 2013 Nov 6;33(45):17908-20. PMID: 24198379.

 

Bethel-Brown C, Yao H, Callen S, et al. HIV-1 Tat-mediated induction of platelet-derived growth factor in astrocytes: role of early growth response gene 1. J Immunol. 2011 Apr 1;186(7):4119-29. PMID: 21368226.

 

Lu SM, Tremblay MÈ, King IL, et al. HIV-1 Tat-induced microgliosis and synaptic damage via interactions between peripheral and central myeloid cells. PLoS One. 2011;6(9):e23915. PMID: 21912650.

" Not dangerous goods.

LKT T0076 Transactivator of Transcription Peptide 2.5 mg 324 Peptide, cell-penetrating fragment of HIV-1 TAT protein. TAT, TAT peptide, YGRKKRRQRRR ≥95% 1558.88 C64H119N33O13 Ambient -20°C "Hargus NJ, Thayer SA. Human immunodeficiency virus-1 Tat protein increases the number of inhibitory synapses between hippocampal neurons in culture. J Neurosci. 2013 Nov 6;33(45):17908-20. PMID: 24198379.

 

Bethel-Brown C, Yao H, Callen S, et al. HIV-1 Tat-mediated induction of platelet-derived growth factor in astrocytes: role of early growth response gene 1. J Immunol. 2011 Apr 1;186(7):4119-29. PMID: 21368226.

 

Lu SM, Tremblay MÈ, King IL, et al. HIV-1 Tat-induced microgliosis and synaptic damage via interactions between peripheral and central myeloid cells. PLoS One. 2011;6(9):e23915. PMID: 21912650.

" Not dangerous goods.

LKT M0374 Masitinib 5 mg 101.9 PDGFR and c-Kit inhibitor. 790299-79-5 ≥98% 498.64 C28H30N6OS CC1=C(C=C(C=C1)NC(=O)C2=CC=C(C=C2)CN3CCN(CC3)C)NC4=NC(=CS4)C5=CN=CC=C5 Ambient Ambient "Smrkovski OA, Essick L, Rohrbach BW, et al. Masitinib mesylate for metastatic and non-resectable canine cutaneous mast cell tumours. Vet Comp Oncol. 2013 Jul 12. [Epub ahead of print]. PMID: 23845124.

 

Fahey CE, Milner RJ, Kow K, et al. Apoptotic effects of the tyrosine kinase inhibitor, masitinib mesylate, on canine osteosarcoma cells. Anticancer Drugs. 2013 Jun;24(5):519-26. PMID: 23466652.

 

Vermersch P, Benrabah R, Schmidt N, et al. Masitinib treatment in patients with progressive multiple sclerosis: a randomized pilot study. BMC Neurol. 2012 Jun 12;12:36. PMID: 22691628.

 

Lee-Fowler TM, Guntur V, Dodam J, et al. The tyrosine kinase inhibitor masitinib blunts airway inflammation and improves associated lung mechanics in a feline model of chronic allergic asthma. Int Arch Allergy Immunol. 2012;158(4):369-74. PMID: 22487554.

 

Cadot P, Hensel P, Bensignor E, et al. Masitinib decreases signs of canine atopic dermatitis: a multicentre, randomized, double-blind, placebo-controlled phase 3 trial. Vet Dermatol. 2011 Dec;22(6):554-64. PMID: 21668810.

 

Piette F, Belmin J, Vincent H, et al. Masitinib as an adjunct therapy for mild-to-moderate Alzheimer's disease: a randomised, placebo-controlled phase 2 trial. Alzheimers Res Ther. 2011 Apr 19;3(2):16. PMID: 21504563.

" Not dangerous goods.

LKT M0374 Masitinib 25 mg 319.4 PDGFR and c-Kit inhibitor. 790299-79-5 ≥98% 498.64 C28H30N6OS CC1=C(C=C(C=C1)NC(=O)C2=CC=C(C=C2)CN3CCN(CC3)C)NC4=NC(=CS4)C5=CN=CC=C5 Ambient Ambient "Smrkovski OA, Essick L, Rohrbach BW, et al. Masitinib mesylate for metastatic and non-resectable canine cutaneous mast cell tumours. Vet Comp Oncol. 2013 Jul 12. [Epub ahead of print]. PMID: 23845124.

 

Fahey CE, Milner RJ, Kow K, et al. Apoptotic effects of the tyrosine kinase inhibitor, masitinib mesylate, on canine osteosarcoma cells. Anticancer Drugs. 2013 Jun;24(5):519-26. PMID: 23466652.

 

Vermersch P, Benrabah R, Schmidt N, et al. Masitinib treatment in patients with progressive multiple sclerosis: a randomized pilot study. BMC Neurol. 2012 Jun 12;12:36. PMID: 22691628.

 

Lee-Fowler TM, Guntur V, Dodam J, et al. The tyrosine kinase inhibitor masitinib blunts airway inflammation and improves associated lung mechanics in a feline model of chronic allergic asthma. Int Arch Allergy Immunol. 2012;158(4):369-74. PMID: 22487554.

 

Cadot P, Hensel P, Bensignor E, et al. Masitinib decreases signs of canine atopic dermatitis: a multicentre, randomized, double-blind, placebo-controlled phase 3 trial. Vet Dermatol. 2011 Dec;22(6):554-64. PMID: 21668810.

 

Piette F, Belmin J, Vincent H, et al. Masitinib as an adjunct therapy for mild-to-moderate Alzheimer's disease: a randomised, placebo-controlled phase 2 trial. Alzheimers Res Ther. 2011 Apr 19;3(2):16. PMID: 21504563.

" Not dangerous goods.

LKT T0008 Tacrolimus 1 mg 47.6 Calcineurin inhibitor. "3S,4R,5S,8R,9E,12S,14S,15R,16S,18R,19R, 26aS)5,6,8,11,12,13,14,15,16,17,18,19,24,25,26,26a-hexadecahydro-5,19-dihydroxy-3-(2-(4-hydroxy-3-methoxycyclohexyl)-14,16-dimethoxy-4,10,12,18-tetramethyl-8-(2-propenyl)-5,19-Epoxy-3H-pyrido(2,1-c)(1,4)oxaazacyclotricosine-1,7,20,21(4H,23H)-tetrone

" FK-506; Fujimycin; Prograf; Protopic; CCRIS 7124. 104987-11-3 ≥98% 804.02 C44H69NO12 CC1CC(C2C(CC(C(O2)(C(=O)C(=O)N3CCCCC3C(=O)OC(C(C(CC(=O)C(C=C(C1)C)CC=C)O)C)C(=CC4CCC(C(C4)OC)O)C)O)C)OC)OC In DMSO at +4 for 2 weeks at -80 for 6 months. Ambient Ambient Soluble in DMSO (20 mg/ml), ethanol (30 mg/ml), acetone, ethyl acetate, diethyl ether or chloroform. "Carr WW. Topical calcineurin inhibitors for atopic dermatitis: review and treatment recommendations. Paediatr Drugs. 2013 Aug;15(4):303-10. PMID: 23549982.

 

Manojlovic Z, Blackmon J, Stefanovic B. Tacrolimus (FK506) prevents early stages of ethanol induced hepatic fibrosis by targeting LARP6 dependent mechanism of collagen synthesis. PLoS One. 2013 Jun 3;8(6):e65897. PMID: 23755290.

 

Grigoriu S, Bond R, Cossio P, et al. The molecular mechanism of substrate engagement and immunosuppressant inhibition of calcineurin. PLoS Biol. 2013;11(2):e1001492. PMID: 23468591.

 

Shin JH, Park HR, Kim SW, et al. The effect of topical FK506 (tacrolimus) in a mouse model of allergic rhinitis. Am J Rhinol Allergy. 2012 Mar-Apr;26(2):e71-5. PMID: 22487280.

 

Izumi S, Nozaki Y, Komori T, et al. Substrate-dependent inhibition of organic anion transporting polypeptide 1B1: comparative analysis with prototypical probe substrates estradiol-17beta-glucuronide, estrone-3-sulfate, and sulfobromophthalein. Drug Metab Dispos. 2013 Oct;41(10):1859-1866. PMID: 23920221.

" Xi, T "UN number: 2811     Class: 6.1     Packing group: III

Proper shipping name: Toxic solid, organic, n.o.s. (Tacrolimus)

Marine pollutant: no     Poison inhalation hazard: no"

LKT T0008 Tacrolimus 5 mg 122.3 Calcineurin inhibitor. "3S,4R,5S,8R,9E,12S,14S,15R,16S,18R,19R, 26aS)5,6,8,11,12,13,14,15,16,17,18,19,24,25,26,26a-hexadecahydro-5,19-dihydroxy-3-(2-(4-hydroxy-3-methoxycyclohexyl)-14,16-dimethoxy-4,10,12,18-tetramethyl-8-(2-propenyl)-5,19-Epoxy-3H-pyrido(2,1-c)(1,4)oxaazacyclotricosine-1,7,20,21(4H,23H)-tetrone

" FK-506; Fujimycin; Prograf; Protopic; CCRIS 7124. 104987-11-3 ≥98% 804.02 C44H69NO12 CC1CC(C2C(CC(C(O2)(C(=O)C(=O)N3CCCCC3C(=O)OC(C(C(CC(=O)C(C=C(C1)C)CC=C)O)C)C(=CC4CCC(C(C4)OC)O)C)O)C)OC)OC In DMSO at +4 for 2 weeks at -80 for 6 months. Ambient Ambient Soluble in DMSO (20 mg/ml), ethanol (30 mg/ml), acetone, ethyl acetate, diethyl ether or chloroform. "Carr WW. Topical calcineurin inhibitors for atopic dermatitis: review and treatment recommendations. Paediatr Drugs. 2013 Aug;15(4):303-10. PMID: 23549982.

 

Manojlovic Z, Blackmon J, Stefanovic B. Tacrolimus (FK506) prevents early stages of ethanol induced hepatic fibrosis by targeting LARP6 dependent mechanism of collagen synthesis. PLoS One. 2013 Jun 3;8(6):e65897. PMID: 23755290.

 

Grigoriu S, Bond R, Cossio P, et al. The molecular mechanism of substrate engagement and immunosuppressant inhibition of calcineurin. PLoS Biol. 2013;11(2):e1001492. PMID: 23468591.

 

Shin JH, Park HR, Kim SW, et al. The effect of topical FK506 (tacrolimus) in a mouse model of allergic rhinitis. Am J Rhinol Allergy. 2012 Mar-Apr;26(2):e71-5. PMID: 22487280.

 

Izumi S, Nozaki Y, Komori T, et al. Substrate-dependent inhibition of organic anion transporting polypeptide 1B1: comparative analysis with prototypical probe substrates estradiol-17beta-glucuronide, estrone-3-sulfate, and sulfobromophthalein. Drug Metab Dispos. 2013 Oct;41(10):1859-1866. PMID: 23920221.

" Xi, T "UN number: 2811     Class: 6.1     Packing group: III

Proper shipping name: Toxic solid, organic, n.o.s. (Tacrolimus)

Marine pollutant: no     Poison inhalation hazard: no"

LKT T0008 Tacrolimus 25 mg 407.7 Calcineurin inhibitor. "3S,4R,5S,8R,9E,12S,14S,15R,16S,18R,19R, 26aS)5,6,8,11,12,13,14,15,16,17,18,19,24,25,26,26a-hexadecahydro-5,19-dihydroxy-3-(2-(4-hydroxy-3-methoxycyclohexyl)-14,16-dimethoxy-4,10,12,18-tetramethyl-8-(2-propenyl)-5,19-Epoxy-3H-pyrido(2,1-c)(1,4)oxaazacyclotricosine-1,7,20,21(4H,23H)-tetrone

" FK-506; Fujimycin; Prograf; Protopic; CCRIS 7124. 104987-11-3 ≥98% 804.02 C44H69NO12 CC1CC(C2C(CC(C(O2)(C(=O)C(=O)N3CCCCC3C(=O)OC(C(C(CC(=O)C(C=C(C1)C)CC=C)O)C)C(=CC4CCC(C(C4)OC)O)C)O)C)OC)OC In DMSO at +4 for 2 weeks at -80 for 6 months. Ambient Ambient Soluble in DMSO (20 mg/ml), ethanol (30 mg/ml), acetone, ethyl acetate, diethyl ether or chloroform. "Carr WW. Topical calcineurin inhibitors for atopic dermatitis: review and treatment recommendations. Paediatr Drugs. 2013 Aug;15(4):303-10. PMID: 23549982.

 

Manojlovic Z, Blackmon J, Stefanovic B. Tacrolimus (FK506) prevents early stages of ethanol induced hepatic fibrosis by targeting LARP6 dependent mechanism of collagen synthesis. PLoS One. 2013 Jun 3;8(6):e65897. PMID: 23755290.

 

Grigoriu S, Bond R, Cossio P, et al. The molecular mechanism of substrate engagement and immunosuppressant inhibition of calcineurin. PLoS Biol. 2013;11(2):e1001492. PMID: 23468591.

 

Shin JH, Park HR, Kim SW, et al. The effect of topical FK506 (tacrolimus) in a mouse model of allergic rhinitis. Am J Rhinol Allergy. 2012 Mar-Apr;26(2):e71-5. PMID: 22487280.

 

Izumi S, Nozaki Y, Komori T, et al. Substrate-dependent inhibition of organic anion transporting polypeptide 1B1: comparative analysis with prototypical probe substrates estradiol-17beta-glucuronide, estrone-3-sulfate, and sulfobromophthalein. Drug Metab Dispos. 2013 Oct;41(10):1859-1866. PMID: 23920221.

" Xi, T "UN number: 2811     Class: 6.1     Packing group: III

Proper shipping name: Toxic solid, organic, n.o.s. (Tacrolimus)

Marine pollutant: no     Poison inhalation hazard: no"

LKT M1565 (±)-S-Methyl-L-cysteine-S-oxide 100 mg 93.8 Organosulfur found in cruciferous vegetables; analog of alliin. Alanine, 3-(methylsulfinyl)-, L-, pyrolyzate S-Methylcysteine sulfoxide; Methyiin, pyrolyzate 6853-87-8 ≥94% 151.19 C4H9NO3S CS(=O)CC(C(=O)O)N Ambient 4°C "Steventon GB. Diurnal variation in the metabolism of S-carboxymethyl-L-cysteine in humans. Drug Metab Dispos. 1999 Sep;27(9):1092-7. PMID: 10460812.

 

Synge RL, Wood JC. (+)-(S-methyl-L-cysteine S-oxide) in cabbage. Biochem J. 1956 Oct;64(2):252-9. PMID: 13363835.

" Not dangerous goods.

LKT M1565 (±)-S-Methyl-L-cysteine-S-oxide 250 mg 187.4 Organosulfur found in cruciferous vegetables; analog of alliin. Alanine, 3-(methylsulfinyl)-, L-, pyrolyzate S-Methylcysteine sulfoxide; Methyiin, pyrolyzate 6853-87-8 ≥94% 151.19 C4H9NO3S CS(=O)CC(C(=O)O)N Ambient 4°C "Steventon GB. Diurnal variation in the metabolism of S-carboxymethyl-L-cysteine in humans. Drug Metab Dispos. 1999 Sep;27(9):1092-7. PMID: 10460812.

 

Synge RL, Wood JC. (+)-(S-methyl-L-cysteine S-oxide) in cabbage. Biochem J. 1956 Oct;64(2):252-9. PMID: 13363835.

" Not dangerous goods.

LKT M1565 (±)-S-Methyl-L-cysteine-S-oxide 1 g 562.5 Organosulfur found in cruciferous vegetables; analog of alliin. Alanine, 3-(methylsulfinyl)-, L-, pyrolyzate S-Methylcysteine sulfoxide; Methyiin, pyrolyzate 6853-87-8 ≥94% 151.19 C4H9NO3S CS(=O)CC(C(=O)O)N Ambient 4°C "Steventon GB. Diurnal variation in the metabolism of S-carboxymethyl-L-cysteine in humans. Drug Metab Dispos. 1999 Sep;27(9):1092-7. PMID: 10460812.

 

Synge RL, Wood JC. (+)-(S-methyl-L-cysteine S-oxide) in cabbage. Biochem J. 1956 Oct;64(2):252-9. PMID: 13363835.

" Not dangerous goods.

LKT T0002 T2 Toxin 1 mg 56.3 Trichothecene mycotoxin produced by Fusarium, alters BBB permeability. Insariotoxin, T2 Trichothecene 21259-20-1 ≥98% 466.52 C24H34O9 CC1=CC2C(CC1OC(=O)CC(C)C)(C3(C(C(C(C34CO4)O2)O)OC(=O)C)C)COC(=O)C Ambient 4°C Dichloromethane, DMSO, Ethanol, Ethyl Acetate. "Xu X, Madden LV, Edwards SG. Modeling the Effects of Environmental Conditions on HT2 and T2 Toxin Accumulation in Field Oat Grains. Phytopathology. 2014 Jan;104(1):57-66. PMID: 23883158.

 

Ravindran J, Agrawal M, Gupta N, et al. Alteration of blood brain barrier permeability by T-2 toxin: Role of MMP-9 and inflammatory cytokines. Toxicology. 2011 Feb 4;280(1-2):44-52. PMID: 21112371.

 

Caloni F, Ranzenigo G, Cremonesi F, et al. Effects of a trichothecene, T-2 toxin, on proliferation and steroid production by porcine granulosa cells. Toxicon. 2009 Sep 1;54(3):337-44. PMID: 19463844.

 

Johnsen H, Odden E, Johnsen BA, et al. Cytotoxicity and effects of T2-toxin on plasma proteins involved in coagulation, fibrinolysis and kallikrein-kinin system. Arch Toxicol. 1988 Jan;61(3):237-40. PMID: 3281632.

" T+, Xi "UN number: 3462     Class: 6.1     Packing Group: I

Proper shipping name: Toxins, extracted from living sources, solid, n.o.s. (T2 Toxin)"

LKT T0002 T2 Toxin 5 mg 221.3 Trichothecene mycotoxin produced by Fusarium, alters BBB permeability. Insariotoxin, T2 Trichothecene 21259-20-1 ≥98% 466.52 C24H34O9 CC1=CC2C(CC1OC(=O)CC(C)C)(C3(C(C(C(C34CO4)O2)O)OC(=O)C)C)COC(=O)C Ambient 4°C Dichloromethane, DMSO, Ethanol, Ethyl Acetate. "Xu X, Madden LV, Edwards SG. Modeling the Effects of Environmental Conditions on HT2 and T2 Toxin Accumulation in Field Oat Grains. Phytopathology. 2014 Jan;104(1):57-66. PMID: 23883158.

 

Ravindran J, Agrawal M, Gupta N, et al. Alteration of blood brain barrier permeability by T-2 toxin: Role of MMP-9 and inflammatory cytokines. Toxicology. 2011 Feb 4;280(1-2):44-52. PMID: 21112371.

 

Caloni F, Ranzenigo G, Cremonesi F, et al. Effects of a trichothecene, T-2 toxin, on proliferation and steroid production by porcine granulosa cells. Toxicon. 2009 Sep 1;54(3):337-44. PMID: 19463844.

 

Johnsen H, Odden E, Johnsen BA, et al. Cytotoxicity and effects of T2-toxin on plasma proteins involved in coagulation, fibrinolysis and kallikrein-kinin system. Arch Toxicol. 1988 Jan;61(3):237-40. PMID: 3281632.

" T+, Xi "UN number: 3462     Class: 6.1     Packing Group: I

Proper shipping name: Toxins, extracted from living sources, solid, n.o.s. (T2 Toxin)"

LKT T0002 T2 Toxin 10 mg 393.8 Trichothecene mycotoxin produced by Fusarium, alters BBB permeability. Insariotoxin, T2 Trichothecene 21259-20-1 ≥98% 466.52 C24H34O9 CC1=CC2C(CC1OC(=O)CC(C)C)(C3(C(C(C(C34CO4)O2)O)OC(=O)C)C)COC(=O)C Ambient 4°C Dichloromethane, DMSO, Ethanol, Ethyl Acetate. "Xu X, Madden LV, Edwards SG. Modeling the Effects of Environmental Conditions on HT2 and T2 Toxin Accumulation in Field Oat Grains. Phytopathology. 2014 Jan;104(1):57-66. PMID: 23883158.

 

Ravindran J, Agrawal M, Gupta N, et al. Alteration of blood brain barrier permeability by T-2 toxin: Role of MMP-9 and inflammatory cytokines. Toxicology. 2011 Feb 4;280(1-2):44-52. PMID: 21112371.

 

Caloni F, Ranzenigo G, Cremonesi F, et al. Effects of a trichothecene, T-2 toxin, on proliferation and steroid production by porcine granulosa cells. Toxicon. 2009 Sep 1;54(3):337-44. PMID: 19463844.

 

Johnsen H, Odden E, Johnsen BA, et al. Cytotoxicity and effects of T2-toxin on plasma proteins involved in coagulation, fibrinolysis and kallikrein-kinin system. Arch Toxicol. 1988 Jan;61(3):237-40. PMID: 3281632.

" T+, Xi "UN number: 3462     Class: 6.1     Packing Group: I

Proper shipping name: Toxins, extracted from living sources, solid, n.o.s. (T2 Toxin)"

LKT M1575 7-Methyl-6-mercaptopurine 50 mg 140.8 Thiopurine antimetabolite; PRPP amidotransferase inhibitor. 1,7-dihydro-7-methyl-6H-Purine-6-thione 7-Methyl-6-thiopurine; 7-Methylpurine-6-thiol 3324-79-6 ≥87% 166.21 C6H6N4S CN1C=NC2=C1C(=S)N=CN2 Ambient -20°C "Bradford K, Shih DQ. Optimizing 6-mercaptopurine and azathioprine therapy in the management of inflammatory bowel disease. World J Gastroenterol. 2011 Oct 7;17(37):4166-73. PMID: 22072847.

 

Nielsen OH, Vainer B, Rask-Madsen J. Review article: the treatment of inflammatory bowel disease with 6-mercaptopurine or azathioprine. Aliment Pharmacol Ther. 2001 Nov;15(11):1699-708. PMID: 11683683.

 

Lennard L, Welch JC, Lilleyman JS. Thiopurine drugs in the treatment of childhood leukaemia: the influence of inherited thiopurine methyltransferase activity on drug metabolism and cytotoxicity. Br J Clin Pharmacol. 1997 Nov;44(5):455-61. PMID: 9384462.

" Not dangerous goods.

LKT M1575 7-Methyl-6-mercaptopurine 100 mg 234.7 Thiopurine antimetabolite; PRPP amidotransferase inhibitor. 1,7-dihydro-7-methyl-6H-Purine-6-thione 7-Methyl-6-thiopurine; 7-Methylpurine-6-thiol 3324-79-6 ≥87% 166.21 C6H6N4S CN1C=NC2=C1C(=S)N=CN2 Ambient -20°C "Bradford K, Shih DQ. Optimizing 6-mercaptopurine and azathioprine therapy in the management of inflammatory bowel disease. World J Gastroenterol. 2011 Oct 7;17(37):4166-73. PMID: 22072847.

 

Nielsen OH, Vainer B, Rask-Madsen J. Review article: the treatment of inflammatory bowel disease with 6-mercaptopurine or azathioprine. Aliment Pharmacol Ther. 2001 Nov;15(11):1699-708. PMID: 11683683.

 

Lennard L, Welch JC, Lilleyman JS. Thiopurine drugs in the treatment of childhood leukaemia: the influence of inherited thiopurine methyltransferase activity on drug metabolism and cytotoxicity. Br J Clin Pharmacol. 1997 Nov;44(5):455-61. PMID: 9384462.

" Not dangerous goods.

LKT M1575 7-Methyl-6-mercaptopurine 500 mg 788.6 Thiopurine antimetabolite; PRPP amidotransferase inhibitor. 1,7-dihydro-7-methyl-6H-Purine-6-thione 7-Methyl-6-thiopurine; 7-Methylpurine-6-thiol 3324-79-6 ≥87% 166.21 C6H6N4S CN1C=NC2=C1C(=S)N=CN2 Ambient -20°C "Bradford K, Shih DQ. Optimizing 6-mercaptopurine and azathioprine therapy in the management of inflammatory bowel disease. World J Gastroenterol. 2011 Oct 7;17(37):4166-73. PMID: 22072847.

 

Nielsen OH, Vainer B, Rask-Madsen J. Review article: the treatment of inflammatory bowel disease with 6-mercaptopurine or azathioprine. Aliment Pharmacol Ther. 2001 Nov;15(11):1699-708. PMID: 11683683.

 

Lennard L, Welch JC, Lilleyman JS. Thiopurine drugs in the treatment of childhood leukaemia: the influence of inherited thiopurine methyltransferase activity on drug metabolism and cytotoxicity. Br J Clin Pharmacol. 1997 Nov;44(5):455-61. PMID: 9384462.

" Not dangerous goods.

LKT ST110 Signal Transduction 1 kit 330.1 Dry Ice -80°C

LKT ST109 Signal Transduction 1 kit 288.8 Dry Ice -80°C

LKT ST108 Signal Transduction 1 kit 866.4 Dry Ice -80°C

LKT ST107 Signal Transduction 1 kit 288.8 Dry Ice -80°C

LKT ST106 Signal Transduction 1 kit 433.3 Dry Ice -80°C

LKT ST105 Signal Transduction 1 kit 165.1 Dry Ice -80°C

LKT ST104 Signal Transduction 1 kit 165.1 Dry Ice -80°C

LKT ST103 Signal Transduction 1 kit 226.9 Dry Ice -80°C

LKT ST102 Signal Transduction 1 kit 2155.4 Dry Ice -80°C

LKT ST101 Signal Transduction 1 kit 2155.4 Dry Ice -80°C

LKT ST100 Signal Transduction 1 kit 148.4 Dry Ice -80°C

LKT SC7056 Snake venom - Crotalus durissus terrificus 100 mg 140 Snake venom found in Crotalus durrisus terrificus; binds N-type and P/Q-type Ca2+ channels, L-type Ca2+ channel potentiator, NMJ blocker. ≥98% "SC7056

" Ambient 4°C "Bucaretchi F, De Capitani EM, Hyslop S, et al. Compartment syndrome after South American rattlesnake (Crotalus durissus terrificus) envenomation. Clin Toxicol (Phila). 2014 Jul;52(6):639-41. PMID: 24940645.

 

Vargas LS, Lara MV, Gonçalves R, et al. The intrahippocampal infusion of crotamine from Crotalus durissus terrificus venom enhances memory persistence in rats. Toxicon. 2014 Jul;85:52-8. PMID: 24813333.

 

Lomeo Rda S, Gonçalves AP, Silva CN, et al. Crotoxin from Crotalus durissus terrificus snake venom induces the release of glutamate from cerebrocortical synaptosomes via N and P/Q calcium channels. Toxicon. 2014 Jul;85:5-16. PMID: 24751366.

 

Yonamine CM, Kondo MY, Nering MB, et al. Enzyme specificity and effects of gyroxin, a serine protease from the venom of the South American rattlesnake Crotalus durissus terrificus, on protease-activated receptors. Toxicon. 2014 Mar;79:64-71. PMID: 24412460.

 

Ribeiro Gde B, Almeida HC, Velarde DT, et al. Study of crotoxin on the induction of paralysis in extraocular muscle in animal model. Arq Bras Oftalmol. 2012 Oct;75(5):307-12. PMID: 23471322.

 

 

"

LKT SB5778 Snake venom - Bothrops neuwiedi diporous 100 mg 279.5 Snake venom found in Bothrops neuwiedi diporus; NMJ blocker. ≥98% Ambient 4°C "Torres AM, Camargo FJ, Ricciardi GA, et al. Neutralizing effects of Nectandra angustifolia extracts against Bothrops neuwiedi snake venom. Nat Prod Commun. 2011 Sep;6(9):1393-6. PMID: 21941922.

 

de Oliveira VC, Lanari LC, Hajos SE, et al. Toxicity of Bothrops neuwiedi complex (""yarará chica"") venom from different regions of Argentina (Serpentes, Viperidae). Toxicon. 2011 Apr;57(5):680-5. PMID: 21300078.

 

Abreu VA, Dal Belo CA, Hernandes-Oliveira SS, Borja-Oliveira CR, et al. Neuromuscular and phospholipase activities of venoms from three subspecies of Bothrops neuwiedi (B. n. goyazensis, B. n. paranaensis and B. n. diporus). Comp Biochem Physiol A Mol Integr Physiol. 2007 Sep;148(1):142-9. PMID: 17524691.

" "UN number: 3462     Class: 6.1     Packing group: I

Proper shipping name: Toxins, extracted from living sources, solid, n.o.s. (Proteinase, Bothrops neuwiedi diporous)

Marine pollutant: No     Poison Inhalation Hazard: No"

LKT SB5776 Snake venom - Bothrops alternatus (urutu) 100 mg 533.8 Snake venom found in Bothrops alternatus urutu. ≥98% Ambient 4°C Dias L, Rodrigues MA, Smaal A, et al. Cardiovascular responses to Bothrops alternatus (Urutu) snake venom in anesthetized dogs. Cardiovasc Toxicol. 2012 Sep;12(3):243-57. PMID: 22528815. "UN number: 3462     Class: 6.1     Packing group: I

Proper shipping name: Toxins, extracted from living sources, solid, n.o.s. (Proteinase, Bothrops alternatus uturu)

Marine pollutant: No     Poison Inhalation Hazard: No"

LKT S9775 Systemin 0.5 mg 107.8 Peptide hormone found in Solanaceae family plants; potential DNA binder. 137181-56-7 ≥95% 2010.32 C85H144N26O28S CC(C)C(C(=O)NC(CCC(=O)N)C(=O)NC(CO)C(=O)NC(CCCCN)C(=O)N1CCCC1C(=O)N2CCCC2C(=O)NC(CO)C(=O)NC(CCCCN)C(=O)NC(CCCN=C(N)N)C(=O)NC(CC(=O)O)C(=O)N3CCCC3C(=O)N4CCCC4C(=O)OC(=O)C(CC(=O)O)NC(=O)C(C(C)O)NC(=O)C(CCC(=O)N)NC(=O)C(CCSC)NC(=O)C(CCCCN)N)NC(=O)C(C)N Ambient -20°C "Pearce G. Systemin, hydroxyproline-rich systemin and the induction of protease inhibitors. Curr Protein Pept Sci. 2011 Aug;12(5):399-408. PMID: 21418016.

 

Bing T, Chang T, Yang X, et al. G-quadruplex DNA aptamers generated for systemin. Bioorg Med Chem. 2011 Jul 15;19(14):4211-9. PMID: 21715176.

 

Sun JQ, Jiang HL, Li CY. Systemin/Jasmonate-mediated systemic defense signaling in tomato. Mol Plant. 2011 Jul;4(4):607-15. PMID: 21357647.

 

Pearce G, Bhattacharya R, Chen YC. Peptide signals for plant defense display a more universal role. Plant Signal Behav. 2008 Dec;3(12):1091-2. PMID: 19704502.

" Not dangerous goods.

LKT S9775 Systemin 1 mg 183 Peptide hormone found in Solanaceae family plants; potential DNA binder. 137181-56-7 ≥95% 2010.32 C85H144N26O28S CC(C)C(C(=O)NC(CCC(=O)N)C(=O)NC(CO)C(=O)NC(CCCCN)C(=O)N1CCCC1C(=O)N2CCCC2C(=O)NC(CO)C(=O)NC(CCCCN)C(=O)NC(CCCN=C(N)N)C(=O)NC(CC(=O)O)C(=O)N3CCCC3C(=O)N4CCCC4C(=O)OC(=O)C(CC(=O)O)NC(=O)C(C(C)O)NC(=O)C(CCC(=O)N)NC(=O)C(CCSC)NC(=O)C(CCCCN)N)NC(=O)C(C)N Ambient -20°C "Pearce G. Systemin, hydroxyproline-rich systemin and the induction of protease inhibitors. Curr Protein Pept Sci. 2011 Aug;12(5):399-408. PMID: 21418016.

 

Bing T, Chang T, Yang X, et al. G-quadruplex DNA aptamers generated for systemin. Bioorg Med Chem. 2011 Jul 15;19(14):4211-9. PMID: 21715176.

 

Sun JQ, Jiang HL, Li CY. Systemin/Jasmonate-mediated systemic defense signaling in tomato. Mol Plant. 2011 Jul;4(4):607-15. PMID: 21357647.

 

Pearce G, Bhattacharya R, Chen YC. Peptide signals for plant defense display a more universal role. Plant Signal Behav. 2008 Dec;3(12):1091-2. PMID: 19704502.

" Not dangerous goods.

LKT S9775 Systemin 2.5 mg 324 Peptide hormone found in Solanaceae family plants; potential DNA binder. 137181-56-7 ≥95% 2010.32 C85H144N26O28S CC(C)C(C(=O)NC(CCC(=O)N)C(=O)NC(CO)C(=O)NC(CCCCN)C(=O)N1CCCC1C(=O)N2CCCC2C(=O)NC(CO)C(=O)NC(CCCCN)C(=O)NC(CCCN=C(N)N)C(=O)NC(CC(=O)O)C(=O)N3CCCC3C(=O)N4CCCC4C(=O)OC(=O)C(CC(=O)O)NC(=O)C(C(C)O)NC(=O)C(CCC(=O)N)NC(=O)C(CCSC)NC(=O)C(CCCCN)N)NC(=O)C(C)N Ambient -20°C "Pearce G. Systemin, hydroxyproline-rich systemin and the induction of protease inhibitors. Curr Protein Pept Sci. 2011 Aug;12(5):399-408. PMID: 21418016.

 

Bing T, Chang T, Yang X, et al. G-quadruplex DNA aptamers generated for systemin. Bioorg Med Chem. 2011 Jul 15;19(14):4211-9. PMID: 21715176.

 

Sun JQ, Jiang HL, Li CY. Systemin/Jasmonate-mediated systemic defense signaling in tomato. Mol Plant. 2011 Jul;4(4):607-15. PMID: 21357647.

 

Pearce G, Bhattacharya R, Chen YC. Peptide signals for plant defense display a more universal role. Plant Signal Behav. 2008 Dec;3(12):1091-2. PMID: 19704502.

" Not dangerous goods.

LKT S9754 Syntide 2 1 mg 120 Synthetic peptide, CDPK, PKC, CaMKII substrate. 108334-68-5 ≥95% 1507.85 C68H122N20O18 CC(C)CC(C(=O)NC(C)C(=O)NC(CCCN=C(N)N)C(=O)NC(C(C)O)C(=O)NC(CC(C)C)C(=O)NC(CO)C(=O)NC(C(C)C)C(=O)NC(C)C(=O)NCC(=O)NC(CC(C)C)C(=O)N1CCCC1C(=O)NCC(=O)NC(CCCCN)C(=O)NC(CCCCN)C(=O)O)NC(=O)C2CCCN2 Ambient -20°C "Lanteri ML, Pagnussat GC, Lamattina L. Calcium and calcium-dependent protein kinases are involved in nitric oxide- and auxin-induced adventitious root formation in cucumber. J Exp Bot. 2006;57(6):1341-51. PMID: 16531462.

 

Szczegielniak J, Klimecka M, Liwosz A, et al. A wound-responsive and phospholipid-regulated maize calcium-dependent protein kinase. Plant Physiol. 2005 Dec;139(4):1970-83. PMID: 16299185.

 

Ishida A, Kameshita I, Okuno S, et al. A novel highly specific and potent inhibitor of calmodulin-dependent protein kinase II. Biochem Biophys Res Commun. 1995 Jul 26;212(3):806-12. PMID: 7626114.

 

Hashimoto Y, Soderling TR. Calcium calmodulin-dependent protein kinase II and calcium phospholipid-dependent protein kinase activities in rat tissues assayed with a synthetic peptide. Arch Biochem Biophys. 1987 Feb 1;252(2):418-25. PMID: 3028265.

" Not dangerous goods.

LKT S9754 Syntide 2 2 mg 204.1 Synthetic peptide, CDPK, PKC, CaMKII substrate. 108334-68-5 ≥95% 1507.85 C68H122N20O18 CC(C)CC(C(=O)NC(C)C(=O)NC(CCCN=C(N)N)C(=O)NC(C(C)O)C(=O)NC(CC(C)C)C(=O)NC(CO)C(=O)NC(C(C)C)C(=O)NC(C)C(=O)NCC(=O)NC(CC(C)C)C(=O)N1CCCC1C(=O)NCC(=O)NC(CCCCN)C(=O)NC(CCCCN)C(=O)O)NC(=O)C2CCCN2 Ambient -20°C "Lanteri ML, Pagnussat GC, Lamattina L. Calcium and calcium-dependent protein kinases are involved in nitric oxide- and auxin-induced adventitious root formation in cucumber. J Exp Bot. 2006;57(6):1341-51. PMID: 16531462.

 

Szczegielniak J, Klimecka M, Liwosz A, et al. A wound-responsive and phospholipid-regulated maize calcium-dependent protein kinase. Plant Physiol. 2005 Dec;139(4):1970-83. PMID: 16299185.

 

Ishida A, Kameshita I, Okuno S, et al. A novel highly specific and potent inhibitor of calmodulin-dependent protein kinase II. Biochem Biophys Res Commun. 1995 Jul 26;212(3):806-12. PMID: 7626114.

 

Hashimoto Y, Soderling TR. Calcium calmodulin-dependent protein kinase II and calcium phospholipid-dependent protein kinase activities in rat tissues assayed with a synthetic peptide. Arch Biochem Biophys. 1987 Feb 1;252(2):418-25. PMID: 3028265.

" Not dangerous goods.

LKT S9754 Syntide 2 5 mg 359.9 Synthetic peptide, CDPK, PKC, CaMKII substrate. 108334-68-5 ≥95% 1507.85 C68H122N20O18 CC(C)CC(C(=O)NC(C)C(=O)NC(CCCN=C(N)N)C(=O)NC(C(C)O)C(=O)NC(CC(C)C)C(=O)NC(CO)C(=O)NC(C(C)C)C(=O)NC(C)C(=O)NCC(=O)NC(CC(C)C)C(=O)N1CCCC1C(=O)NCC(=O)NC(CCCCN)C(=O)NC(CCCCN)C(=O)O)NC(=O)C2CCCN2 Ambient -20°C "Lanteri ML, Pagnussat GC, Lamattina L. Calcium and calcium-dependent protein kinases are involved in nitric oxide- and auxin-induced adventitious root formation in cucumber. J Exp Bot. 2006;57(6):1341-51. PMID: 16531462.

 

Szczegielniak J, Klimecka M, Liwosz A, et al. A wound-responsive and phospholipid-regulated maize calcium-dependent protein kinase. Plant Physiol. 2005 Dec;139(4):1970-83. PMID: 16299185.

 

Ishida A, Kameshita I, Okuno S, et al. A novel highly specific and potent inhibitor of calmodulin-dependent protein kinase II. Biochem Biophys Res Commun. 1995 Jul 26;212(3):806-12. PMID: 7626114.

 

Hashimoto Y, Soderling TR. Calcium calmodulin-dependent protein kinase II and calcium phospholipid-dependent protein kinase activities in rat tissues assayed with a synthetic peptide. Arch Biochem Biophys. 1987 Feb 1;252(2):418-25. PMID: 3028265.

" Not dangerous goods.

LKT S9753 Synephrine 1 g 40.7 Endogenous alkaloid also found in citrus fruits, Evodia, Zanthoxylum; adrenergic, TAAR-1, 5-HT agonist. 4-Hydroxy-α-[(methylamino)methyl]benzenemethanol Analeptin; Ethaphene; Oxedrine; Parasympatol; Simpalon; Synerphrin; Synthenate 94-07-5 ≥98% 167.21 C9H13NO2 CNCC(C1=CC=C(C=C1)O)O Ambient Ambient Soluble in water. "Wu Q, Li R, Soromou LW, et al. p-Synephrine suppresses lipopolysaccharide-induced acute lung injury by inhibition of the NF-κB signaling pathway. Inflamm Res. 2014 Jun;63(6):429-39. PMID: 24487736.

 

Ozçelik B, Kartal M, Orhan I. Cytotoxicity, antiviral and antimicrobial activities of alkaloids, flavonoids, and phenolic acids. Pharm Biol. 2011 Apr;49(4):396-402. PMID: 21391841.

 

Fang YS, Shan DM, Liu JW, et al. Effect of constituents from Fructus Aurantii Immaturus and Radix Paeoniae Alba on gastrointestinal movement. Planta Med. 2009 Jan;75(1):24-31. PMID: 19016407.

 

Endoh M, Schümann HJ, Krappitz N, et al. alpha-Adrenoceptors mediating positive inotropic effects on the ventricular myocardium: some aspects of structure-activity relationship of sympathomimetic amines. Jpn J Pharmacol. 1976 Apr;26(2):179-90. PMID: 7694.

" Xi Not dangerous goods.

LKT S9753 Synephrine 5 g 57.1 Endogenous alkaloid also found in citrus fruits, Evodia, Zanthoxylum; adrenergic, TAAR-1, 5-HT agonist. 4-Hydroxy-α-[(methylamino)methyl]benzenemethanol Analeptin; Ethaphene; Oxedrine; Parasympatol; Simpalon; Synerphrin; Synthenate 94-07-5 ≥98% 167.21 C9H13NO2 CNCC(C1=CC=C(C=C1)O)O Ambient Ambient Soluble in water. "Wu Q, Li R, Soromou LW, et al. p-Synephrine suppresses lipopolysaccharide-induced acute lung injury by inhibition of the NF-κB signaling pathway. Inflamm Res. 2014 Jun;63(6):429-39. PMID: 24487736.

 

Ozçelik B, Kartal M, Orhan I. Cytotoxicity, antiviral and antimicrobial activities of alkaloids, flavonoids, and phenolic acids. Pharm Biol. 2011 Apr;49(4):396-402. PMID: 21391841.

 

Fang YS, Shan DM, Liu JW, et al. Effect of constituents from Fructus Aurantii Immaturus and Radix Paeoniae Alba on gastrointestinal movement. Planta Med. 2009 Jan;75(1):24-31. PMID: 19016407.

 

Endoh M, Schümann HJ, Krappitz N, et al. alpha-Adrenoceptors mediating positive inotropic effects on the ventricular myocardium: some aspects of structure-activity relationship of sympathomimetic amines. Jpn J Pharmacol. 1976 Apr;26(2):179-90. PMID: 7694.

" Xi Not dangerous goods.

LKT S9753 Synephrine 10 g 95.1 Endogenous alkaloid also found in citrus fruits, Evodia, Zanthoxylum; adrenergic, TAAR-1, 5-HT agonist. 4-Hydroxy-α-[(methylamino)methyl]benzenemethanol Analeptin; Ethaphene; Oxedrine; Parasympatol; Simpalon; Synerphrin; Synthenate 94-07-5 ≥98% 167.21 C9H13NO2 CNCC(C1=CC=C(C=C1)O)O Ambient Ambient Soluble in water. "Wu Q, Li R, Soromou LW, et al. p-Synephrine suppresses lipopolysaccharide-induced acute lung injury by inhibition of the NF-κB signaling pathway. Inflamm Res. 2014 Jun;63(6):429-39. PMID: 24487736.

 

Ozçelik B, Kartal M, Orhan I. Cytotoxicity, antiviral and antimicrobial activities of alkaloids, flavonoids, and phenolic acids. Pharm Biol. 2011 Apr;49(4):396-402. PMID: 21391841.

 

Fang YS, Shan DM, Liu JW, et al. Effect of constituents from Fructus Aurantii Immaturus and Radix Paeoniae Alba on gastrointestinal movement. Planta Med. 2009 Jan;75(1):24-31. PMID: 19016407.

 

Endoh M, Schümann HJ, Krappitz N, et al. alpha-Adrenoceptors mediating positive inotropic effects on the ventricular myocardium: some aspects of structure-activity relationship of sympathomimetic amines. Jpn J Pharmacol. 1976 Apr;26(2):179-90. PMID: 7694.

" Xi Not dangerous goods.

LKT S8251 Sulfluramid 500 mg 79.8 Perfluorinated insecticide. "1-Octanesulfonamide, N-ethyl-1,1,2,2,3,3, 4,4,5,5,6,6,7,7,8,8,8-heptadecafluoro- 

" Finitron; Mirex S; GX 071; AL 3-29757; HSDB 7100. 4151-50-2 ≥95% 527.2 C10H6F17NO2S CCNS(=O)(=O)C(C(C(C(C(C(C(C(F)(F)F)(F)F)(F)F)(F)F)(F)F)(F)F)(F)F)(F)F Stable at room temperature. Ambient Ambient Insoluble in water. Soluble in acetone. "Ripa R, Luppichini P, Su NY, et al. Field evaluation of potential control strategies against the invasive eastern subterranean termite (Isoptera: Rhinotermitidae) in Chile. J Econ Entomol. 2007 Aug;100(4):1391-9. PMID: 17849893.

 

Peden-Adams MM, EuDaly JG, Dabra S, et al. Suppression of humoral immunity following exposure to the perfluorinated insecticide sulfluramid. J Toxicol Environ Health A. 2007 Jul;70(13):1130-41. PMID: 17558808.

 

Schal C. Sulfluramid resistance and vapor toxicity in field-collected German cockroaches (Dictyoptera: Blattellidae). J Med Entomol. 1992 Mar;29(2):207-15. PMID: 1495031.

" Xn, N "UN number: 3077     Class: 9     Packing Group: III

Proper shipping name: Environmentally hazardous substance, solid, n.o.s. (Sulfluramid)"

LKT S8251 Sulfluramid 1 g 115.5 Perfluorinated insecticide. "1-Octanesulfonamide, N-ethyl-1,1,2,2,3,3, 4,4,5,5,6,6,7,7,8,8,8-heptadecafluoro- 

" Finitron; Mirex S; GX 071; AL 3-29757; HSDB 7100. 4151-50-2 ≥95% 527.2 C10H6F17NO2S CCNS(=O)(=O)C(C(C(C(C(C(C(C(F)(F)F)(F)F)(F)F)(F)F)(F)F)(F)F)(F)F)(F)F Stable at room temperature. Ambient Ambient Insoluble in water. Soluble in acetone. "Ripa R, Luppichini P, Su NY, et al. Field evaluation of potential control strategies against the invasive eastern subterranean termite (Isoptera: Rhinotermitidae) in Chile. J Econ Entomol. 2007 Aug;100(4):1391-9. PMID: 17849893.

 

Peden-Adams MM, EuDaly JG, Dabra S, et al. Suppression of humoral immunity following exposure to the perfluorinated insecticide sulfluramid. J Toxicol Environ Health A. 2007 Jul;70(13):1130-41. PMID: 17558808.

 

Schal C. Sulfluramid resistance and vapor toxicity in field-collected German cockroaches (Dictyoptera: Blattellidae). J Med Entomol. 1992 Mar;29(2):207-15. PMID: 1495031.

" Xn, N "UN number: 3077     Class: 9     Packing Group: III

Proper shipping name: Environmentally hazardous substance, solid, n.o.s. (Sulfluramid)"

LKT S8251 Sulfluramid 5 g 462.1 Perfluorinated insecticide. "1-Octanesulfonamide, N-ethyl-1,1,2,2,3,3, 4,4,5,5,6,6,7,7,8,8,8-heptadecafluoro- 

" Finitron; Mirex S; GX 071; AL 3-29757; HSDB 7100. 4151-50-2 ≥95% 527.2 C10H6F17NO2S CCNS(=O)(=O)C(C(C(C(C(C(C(C(F)(F)F)(F)F)(F)F)(F)F)(F)F)(F)F)(F)F)(F)F Stable at room temperature. Ambient Ambient Insoluble in water. Soluble in acetone. "Ripa R, Luppichini P, Su NY, et al. Field evaluation of potential control strategies against the invasive eastern subterranean termite (Isoptera: Rhinotermitidae) in Chile. J Econ Entomol. 2007 Aug;100(4):1391-9. PMID: 17849893.

 

Peden-Adams MM, EuDaly JG, Dabra S, et al. Suppression of humoral immunity following exposure to the perfluorinated insecticide sulfluramid. J Toxicol Environ Health A. 2007 Jul;70(13):1130-41. PMID: 17558808.

 

Schal C. Sulfluramid resistance and vapor toxicity in field-collected German cockroaches (Dictyoptera: Blattellidae). J Med Entomol. 1992 Mar;29(2):207-15. PMID: 1495031.

" Xn, N "UN number: 3077     Class: 9     Packing Group: III

Proper shipping name: Environmentally hazardous substance, solid, n.o.s. (Sulfluramid)"

LKT S8248 Sulfamethoxazole 10 g 31.7 Sulfonamide; PABA inhibitor. 4-Amino-N-(5-methyl-3-isoxazolyl)benzenesulfon- amide Sulfisomezole; Sulfamethylisoxazole; Sulfamethoxizole; Gantanol; Sinomin 723-46-6 ≥98% 253.28 C10H11N3O3S CC1=CC(=NO1)NS(=O)(=O)C2=CC=C(C=C2)N Ambient Ambient Insoluble in water. "Jacobs RF, Wilson CB. Intracellular penetration and antimicrobial activity of antibiotics. J Antimicrob Chemother. 1983 Oct;12 Suppl C:13-20. PMID: 6605963.

 

Gleckman R, Alvarez S, Joubert DW. Drug therapy reviews: trimethoprim-sulfamethoxazole. Am J Hosp Pharm. 1979 Jul;36(7):893-906. PMID: 382841.

 

Lewis EL, Lacey RW. Present significance of resistance to trimethoprim and sulphonamides in coliforms, Staphylococcus aureus, and Streptococcus faecalis. J Clin Pathol. 1973 Mar;26(3):175-80. PMID: 4633678.

" Xi Not dangerous goods.

LKT S8248 Sulfamethoxazole 25 g 57.1 Sulfonamide; PABA inhibitor. 4-Amino-N-(5-methyl-3-isoxazolyl)benzenesulfon- amide Sulfisomezole; Sulfamethylisoxazole; Sulfamethoxizole; Gantanol; Sinomin 723-46-6 ≥98% 253.28 C10H11N3O3S CC1=CC(=NO1)NS(=O)(=O)C2=CC=C(C=C2)N Ambient Ambient Insoluble in water. "Jacobs RF, Wilson CB. Intracellular penetration and antimicrobial activity of antibiotics. J Antimicrob Chemother. 1983 Oct;12 Suppl C:13-20. PMID: 6605963.

 

Gleckman R, Alvarez S, Joubert DW. Drug therapy reviews: trimethoprim-sulfamethoxazole. Am J Hosp Pharm. 1979 Jul;36(7):893-906. PMID: 382841.

 

Lewis EL, Lacey RW. Present significance of resistance to trimethoprim and sulphonamides in coliforms, Staphylococcus aureus, and Streptococcus faecalis. J Clin Pathol. 1973 Mar;26(3):175-80. PMID: 4633678.

" Xi Not dangerous goods.

LKT S8248 Sulfamethoxazole 100 g 165.1 Sulfonamide; PABA inhibitor. 4-Amino-N-(5-methyl-3-isoxazolyl)benzenesulfon- amide Sulfisomezole; Sulfamethylisoxazole; Sulfamethoxizole; Gantanol; Sinomin 723-46-6 ≥98% 253.28 C10H11N3O3S CC1=CC(=NO1)NS(=O)(=O)C2=CC=C(C=C2)N Ambient Ambient Insoluble in water. "Jacobs RF, Wilson CB. Intracellular penetration and antimicrobial activity of antibiotics. J Antimicrob Chemother. 1983 Oct;12 Suppl C:13-20. PMID: 6605963.

 

Gleckman R, Alvarez S, Joubert DW. Drug therapy reviews: trimethoprim-sulfamethoxazole. Am J Hosp Pharm. 1979 Jul;36(7):893-906. PMID: 382841.

 

Lewis EL, Lacey RW. Present significance of resistance to trimethoprim and sulphonamides in coliforms, Staphylococcus aureus, and Streptococcus faecalis. J Clin Pathol. 1973 Mar;26(3):175-80. PMID: 4633678.

" Xi Not dangerous goods.

LKT S8247 Sulfasalazine 10 g 50.3 Mesalazine derivative, sulfa drug; sepiapterin reductase inhibitor, NMDA antagonist. 2-Hydroxy-5-[[4-[(2-pyridinylamino)sulfonyl]phenyl]- azo]benzoic acid Azulfidine; ColoPleon; Salazopyrin 599-79-1 ≥98% 398.39 C18H14N4O5S C1=CC=NC(=C1)NS(=O)(=O)C2=CC=C(C=C2)NN=C3C=CC(=O)C(=C3)C(=O)O Ambient Ambient Slightly soluble in alcohol (0.3 mg/mL) and methanol (0.6 mg/mL). Practically insoluble in water, benzene, chloroform and ether. "Costigan M, Latremoliere A, Woolf CJ. Analgesia by inhibiting tetrahydrobiopterin synthesis. Curr Opin Pharmacol. 2012 Feb;12(1):92-9. PMID: 22178186.

 

Couto D, Ribeiro D, Freitas M, et al. Scavenging of reactive oxygen and nitrogen species by the prodrug sulfasalazine and its metabolites 5-aminosalicylic acid and sulfapyridine. Redox Rep. 2010;15(6):259-67. PMID: 21208525.

 

Noh JH, Gwag BJ, Chung JM. Underlying mechanism for NMDA receptor antagonism by the anti-inflammatory drug, sulfasalazine, in mouse cortical neurons. Neuropharmacology. 2006 Jan;50(1):1-15. PMID: 16169564.

 

Oakley F, Meso M, Iredale JP, et al. Inhibition of inhibitor of kappaB kinases stimulates hepatic stellate cell apoptosis and accelerated recovery from rat liver fibrosis. Gastroenterology. 2005 Jan;128(1):108-20. PMID: 15633128.

 

Fleischmann R. Safety and efficacy of disease-modifying antirheumatic agents in rheumatoid arthritis and juvenile rheumatoid arthritis. Expert Opin Drug Saf. 2003 Jul;2(4):347-65. PMID: 12904092.

" Xn Not dangerous goods.

LKT S8247 Sulfasalazine 50 g 157.3 Mesalazine derivative, sulfa drug; sepiapterin reductase inhibitor, NMDA antagonist. 2-Hydroxy-5-[[4-[(2-pyridinylamino)sulfonyl]phenyl]- azo]benzoic acid Azulfidine; ColoPleon; Salazopyrin 599-79-1 ≥98% 398.39 C18H14N4O5S C1=CC=NC(=C1)NS(=O)(=O)C2=CC=C(C=C2)NN=C3C=CC(=O)C(=C3)C(=O)O Ambient Ambient Slightly soluble in alcohol (0.3 mg/mL) and methanol (0.6 mg/mL). Practically insoluble in water, benzene, chloroform and ether. "Costigan M, Latremoliere A, Woolf CJ. Analgesia by inhibiting tetrahydrobiopterin synthesis. Curr Opin Pharmacol. 2012 Feb;12(1):92-9. PMID: 22178186.

 

Couto D, Ribeiro D, Freitas M, et al. Scavenging of reactive oxygen and nitrogen species by the prodrug sulfasalazine and its metabolites 5-aminosalicylic acid and sulfapyridine. Redox Rep. 2010;15(6):259-67. PMID: 21208525.

 

Noh JH, Gwag BJ, Chung JM. Underlying mechanism for NMDA receptor antagonism by the anti-inflammatory drug, sulfasalazine, in mouse cortical neurons. Neuropharmacology. 2006 Jan;50(1):1-15. PMID: 16169564.

 

Oakley F, Meso M, Iredale JP, et al. Inhibition of inhibitor of kappaB kinases stimulates hepatic stellate cell apoptosis and accelerated recovery from rat liver fibrosis. Gastroenterology. 2005 Jan;128(1):108-20. PMID: 15633128.

 

Fleischmann R. Safety and efficacy of disease-modifying antirheumatic agents in rheumatoid arthritis and juvenile rheumatoid arthritis. Expert Opin Drug Saf. 2003 Jul;2(4):347-65. PMID: 12904092.

" Xn Not dangerous goods.

LKT S8247 Sulfasalazine 100 g 251.7 Mesalazine derivative, sulfa drug; sepiapterin reductase inhibitor, NMDA antagonist. 2-Hydroxy-5-[[4-[(2-pyridinylamino)sulfonyl]phenyl]- azo]benzoic acid Azulfidine; ColoPleon; Salazopyrin 599-79-1 ≥98% 398.39 C18H14N4O5S C1=CC=NC(=C1)NS(=O)(=O)C2=CC=C(C=C2)NN=C3C=CC(=O)C(=C3)C(=O)O Ambient Ambient Slightly soluble in alcohol (0.3 mg/mL) and methanol (0.6 mg/mL). Practically insoluble in water, benzene, chloroform and ether. "Costigan M, Latremoliere A, Woolf CJ. Analgesia by inhibiting tetrahydrobiopterin synthesis. Curr Opin Pharmacol. 2012 Feb;12(1):92-9. PMID: 22178186.

 

Couto D, Ribeiro D, Freitas M, et al. Scavenging of reactive oxygen and nitrogen species by the prodrug sulfasalazine and its metabolites 5-aminosalicylic acid and sulfapyridine. Redox Rep. 2010;15(6):259-67. PMID: 21208525.

 

Noh JH, Gwag BJ, Chung JM. Underlying mechanism for NMDA receptor antagonism by the anti-inflammatory drug, sulfasalazine, in mouse cortical neurons. Neuropharmacology. 2006 Jan;50(1):1-15. PMID: 16169564.

 

Oakley F, Meso M, Iredale JP, et al. Inhibition of inhibitor of kappaB kinases stimulates hepatic stellate cell apoptosis and accelerated recovery from rat liver fibrosis. Gastroenterology. 2005 Jan;128(1):108-20. PMID: 15633128.

 

Fleischmann R. Safety and efficacy of disease-modifying antirheumatic agents in rheumatoid arthritis and juvenile rheumatoid arthritis. Expert Opin Drug Saf. 2003 Jul;2(4):347-65. PMID: 12904092.

" Xn Not dangerous goods.

LKT S8246 Sulfadimethoxine 10 g 50 Sulfonamide; folic acid synthesis inhibitor. 4-Amino-N-(2,6-dimethoxy-4-pyrimidinyl)benzene- sulfonamide Agribon; Albon; Arnosulfan; Diasulfa; Madribon; Neostreptal; Sudine; Sulfabon; Ultrasulfon 122-11-2 ≥98% 310.33 C12H14N4O4S COC1=NC(=NC(=C1)NS(=O)(=O)C2=CC=C(C=C2)N)OC Ambient Ambient Soluble in dilute HCl, and in aqueous solutions of sodium carbonate. Ethanol (5 mg/mL). "Zessel K, Mohring S, Hamscher G, et al. Biocompatibility and antibacterial activity of photolytic products of sulfonamides. Chemosphere. 2014 Apr;100:167-74. PMID: 24321335.

 

Mengelers MJ, van Klingeren B, van Miert AS. In vitro antimicrobial activity of sulfonamides against some porcine pathogens. Am J Vet Res. 1989 Jul;50(7):1022-8. PMID: 2774319.

" Xi Not dangerous goods.

LKT S8246 Sulfadimethoxine 25 g 96.2 Sulfonamide; folic acid synthesis inhibitor. 4-Amino-N-(2,6-dimethoxy-4-pyrimidinyl)benzene- sulfonamide Agribon; Albon; Arnosulfan; Diasulfa; Madribon; Neostreptal; Sudine; Sulfabon; Ultrasulfon 122-11-2 ≥98% 310.33 C12H14N4O4S COC1=NC(=NC(=C1)NS(=O)(=O)C2=CC=C(C=C2)N)OC Ambient Ambient Soluble in dilute HCl, and in aqueous solutions of sodium carbonate. Ethanol (5 mg/mL). "Zessel K, Mohring S, Hamscher G, et al. Biocompatibility and antibacterial activity of photolytic products of sulfonamides. Chemosphere. 2014 Apr;100:167-74. PMID: 24321335.

 

Mengelers MJ, van Klingeren B, van Miert AS. In vitro antimicrobial activity of sulfonamides against some porcine pathogens. Am J Vet Res. 1989 Jul;50(7):1022-8. PMID: 2774319.

" Xi Not dangerous goods.

LKT S8246 Sulfadimethoxine 100 g 260.6 Sulfonamide; folic acid synthesis inhibitor. 4-Amino-N-(2,6-dimethoxy-4-pyrimidinyl)benzene- sulfonamide Agribon; Albon; Arnosulfan; Diasulfa; Madribon; Neostreptal; Sudine; Sulfabon; Ultrasulfon 122-11-2 ≥98% 310.33 C12H14N4O4S COC1=NC(=NC(=C1)NS(=O)(=O)C2=CC=C(C=C2)N)OC Ambient Ambient Soluble in dilute HCl, and in aqueous solutions of sodium carbonate. Ethanol (5 mg/mL). "Zessel K, Mohring S, Hamscher G, et al. Biocompatibility and antibacterial activity of photolytic products of sulfonamides. Chemosphere. 2014 Apr;100:167-74. PMID: 24321335.

 

Mengelers MJ, van Klingeren B, van Miert AS. In vitro antimicrobial activity of sulfonamides against some porcine pathogens. Am J Vet Res. 1989 Jul;50(7):1022-8. PMID: 2774319.

" Xi Not dangerous goods.

LKT S8245 Sulfadiazine 50 g 30.7 Sulfonamide; folate production inhibitor. 4-Amino-N-2-pyrimidinylbenzenesulfonamide Adiazine; Diazyl; Sulfolex 68-35-9 ≥98% 250.28 C10H10N4O2S C1=CN=C(N=C1)NS(=O)(=O)C2=CC=C(C=C2)N Ambient Ambient Insoluble in water. Sparingly soluble in alcohol or acetone. "Laue H, Weiss L, Bernardi A, et al. In vitro activity of the novel diaminopyrimidine, iclaprim, in combination with folate inhibitors and other antimicrobials with different mechanisms of action. J Antimicrob Chemother. 2007 Dec;60(6):1391-4. PMID: 17962215.

 

Richards RM, Xing JZ, Gregory DW, et al.  Mechanism of sulphadiazine enhancement of trimethoprim activity against sulphadiazine-resistant Enterococcus faecalis. J Antimicrob Chemother. 1995 Oct;36(4):607-18. PMID: 8591935.

 

Ho YB, Zakaria MP, Latif PA, Saari N. Occurrence of veterinary antibiotics and progesterone in broiler manure and agricultural soil in Malaysia. Sci Total Environ. 2014 Aug 1;488-489:261-267. PMID: 24836135.

" Xn Not dangerous goods.

LKT S8245 Sulfadiazine 100 g 51.1 Sulfonamide; folate production inhibitor. 4-Amino-N-2-pyrimidinylbenzenesulfonamide Adiazine; Diazyl; Sulfolex 68-35-9 ≥98% 250.28 C10H10N4O2S C1=CN=C(N=C1)NS(=O)(=O)C2=CC=C(C=C2)N Ambient Ambient Insoluble in water. Sparingly soluble in alcohol or acetone. "Laue H, Weiss L, Bernardi A, et al. In vitro activity of the novel diaminopyrimidine, iclaprim, in combination with folate inhibitors and other antimicrobials with different mechanisms of action. J Antimicrob Chemother. 2007 Dec;60(6):1391-4. PMID: 17962215.

 

Richards RM, Xing JZ, Gregory DW, et al.  Mechanism of sulphadiazine enhancement of trimethoprim activity against sulphadiazine-resistant Enterococcus faecalis. J Antimicrob Chemother. 1995 Oct;36(4):607-18. PMID: 8591935.

 

Ho YB, Zakaria MP, Latif PA, Saari N. Occurrence of veterinary antibiotics and progesterone in broiler manure and agricultural soil in Malaysia. Sci Total Environ. 2014 Aug 1;488-489:261-267. PMID: 24836135.

" Xn Not dangerous goods.

LKT S8245 Sulfadiazine 500 g 181.7 Sulfonamide; folate production inhibitor. 4-Amino-N-2-pyrimidinylbenzenesulfonamide Adiazine; Diazyl; Sulfolex 68-35-9 ≥98% 250.28 C10H10N4O2S C1=CN=C(N=C1)NS(=O)(=O)C2=CC=C(C=C2)N Ambient Ambient Insoluble in water. Sparingly soluble in alcohol or acetone. "Laue H, Weiss L, Bernardi A, et al. In vitro activity of the novel diaminopyrimidine, iclaprim, in combination with folate inhibitors and other antimicrobials with different mechanisms of action. J Antimicrob Chemother. 2007 Dec;60(6):1391-4. PMID: 17962215.

 

Richards RM, Xing JZ, Gregory DW, et al.  Mechanism of sulphadiazine enhancement of trimethoprim activity against sulphadiazine-resistant Enterococcus faecalis. J Antimicrob Chemother. 1995 Oct;36(4):607-18. PMID: 8591935.

 

Ho YB, Zakaria MP, Latif PA, Saari N. Occurrence of veterinary antibiotics and progesterone in broiler manure and agricultural soil in Malaysia. Sci Total Environ. 2014 Aug 1;488-489:261-267. PMID: 24836135.

" Xn Not dangerous goods.

LKT S8244 Sulbactam 500 mg 67.9 β-lactamase inhibitor. (2S,5R)-3,3-Dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid CP 45899 68373-14-8 ≥98% 233.25 C8H11NO5S CC1(C(N2C(S1(=O)=O)CC2=O)C(=O)O)C Ambient Ambient Soluble in water. "Li R, Liao JM, Gu CR, et al. Theoretical investigation on reaction of sulbactam with wild-type SHV-1 β-lactamase: acylation, tautomerization, and deacylation. J Phys Chem B. 2011 Sep 1;115(34):10298-310. PMID: 21797222.

 

Drawz SM, Bonomo RA. Three decades of beta-lactamase inhibitors. Clin Microbiol Rev. 2010 Jan;23(1):160-201. PMID: 20065329.

" Xn Not dangerous goods.

LKT S8244 Sulbactam 1 g 101.9 β-lactamase inhibitor. (2S,5R)-3,3-Dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid CP 45899 68373-14-8 ≥98% 233.25 C8H11NO5S CC1(C(N2C(S1(=O)=O)CC2=O)C(=O)O)C Ambient Ambient Soluble in water. "Li R, Liao JM, Gu CR, et al. Theoretical investigation on reaction of sulbactam with wild-type SHV-1 β-lactamase: acylation, tautomerization, and deacylation. J Phys Chem B. 2011 Sep 1;115(34):10298-310. PMID: 21797222.

 

Drawz SM, Bonomo RA. Three decades of beta-lactamase inhibitors. Clin Microbiol Rev. 2010 Jan;23(1):160-201. PMID: 20065329.

" Xn Not dangerous goods.

LKT S8244 Sulbactam 5 g 339.8 β-lactamase inhibitor. (2S,5R)-3,3-Dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid CP 45899 68373-14-8 ≥98% 233.25 C8H11NO5S CC1(C(N2C(S1(=O)=O)CC2=O)C(=O)O)C Ambient Ambient Soluble in water. "Li R, Liao JM, Gu CR, et al. Theoretical investigation on reaction of sulbactam with wild-type SHV-1 β-lactamase: acylation, tautomerization, and deacylation. J Phys Chem B. 2011 Sep 1;115(34):10298-310. PMID: 21797222.

 

Drawz SM, Bonomo RA. Three decades of beta-lactamase inhibitors. Clin Microbiol Rev. 2010 Jan;23(1):160-201. PMID: 20065329.

" Xn Not dangerous goods.

LKT S8147 Sulindac Sulfide 25 mg 123.8 NSAID; COX-1/2 and PDE inhibitor. "1H-Indene-3-acetic acid, 5-fluoro-2-methyl-1-(p-

(methylthio)benzylidene)- " 32004-67-4 ≥98% 340.41 C20H17FO2S CC1=C(C2=C(C1=CC3=CC=C(C=C3)SC)C=CC(=C2)F)CC(=O)O Ambient Ambient Soluble in DMSO (>20 mg/mL) or ethanol. "Modi JP, Gharibani PM, Ma Z, et al. Protective mechanism of sulindac in an animal model of ischemic stroke. Brain Res. 2014 Aug 12;1576:91-9. PMID: 24968090.

 

Li N, Xi Y, Tinsley HN, et al. Sulindac selectively inhibits colon tumor cell growth by activating the cGMP/PKG pathway to suppress Wnt/β-catenin signaling. Mol Cancer Ther. 2013 Sep;12(9):1848-59. PMID: 23804703.

 

Li X, Gao L, Cui Q, et al. Sulindac inhibits tumor cell invasion by suppressing NF-κB-mediated transcription of microRNAs. Oncogene. 2012 Nov 29;31(48):4979-86. PMID: 22286762.

 

Scheper MA, Nikitakis NG, Chaisuparat R, et al. Sulindac induces apoptosis and inhibits tumor growth in vivo in head and neck squamous cell carcinoma. Neoplasia. 2007 Mar;9(3):192-9. PMID: 17401459.

" Xn Not dangerous goods.

LKT S8147 Sulindac Sulfide 100 mg 343.4 NSAID; COX-1/2 and PDE inhibitor. "1H-Indene-3-acetic acid, 5-fluoro-2-methyl-1-(p-

(methylthio)benzylidene)- " 32004-67-4 ≥98% 340.41 C20H17FO2S CC1=C(C2=C(C1=CC3=CC=C(C=C3)SC)C=CC(=C2)F)CC(=O)O Ambient Ambient Soluble in DMSO (>20 mg/mL) or ethanol. "Modi JP, Gharibani PM, Ma Z, et al. Protective mechanism of sulindac in an animal model of ischemic stroke. Brain Res. 2014 Aug 12;1576:91-9. PMID: 24968090.

 

Li N, Xi Y, Tinsley HN, et al. Sulindac selectively inhibits colon tumor cell growth by activating the cGMP/PKG pathway to suppress Wnt/β-catenin signaling. Mol Cancer Ther. 2013 Sep;12(9):1848-59. PMID: 23804703.

 

Li X, Gao L, Cui Q, et al. Sulindac inhibits tumor cell invasion by suppressing NF-κB-mediated transcription of microRNAs. Oncogene. 2012 Nov 29;31(48):4979-86. PMID: 22286762.

 

Scheper MA, Nikitakis NG, Chaisuparat R, et al. Sulindac induces apoptosis and inhibits tumor growth in vivo in head and neck squamous cell carcinoma. Neoplasia. 2007 Mar;9(3):192-9. PMID: 17401459.

" Xn Not dangerous goods.

LKT S8147 Sulindac Sulfide 500 mg 1098.1 NSAID; COX-1/2 and PDE inhibitor. "1H-Indene-3-acetic acid, 5-fluoro-2-methyl-1-(p-

(methylthio)benzylidene)- " 32004-67-4 ≥98% 340.41 C20H17FO2S CC1=C(C2=C(C1=CC3=CC=C(C=C3)SC)C=CC(=C2)F)CC(=O)O Ambient Ambient Soluble in DMSO (>20 mg/mL) or ethanol. "Modi JP, Gharibani PM, Ma Z, et al. Protective mechanism of sulindac in an animal model of ischemic stroke. Brain Res. 2014 Aug 12;1576:91-9. PMID: 24968090.

 

Li N, Xi Y, Tinsley HN, et al. Sulindac selectively inhibits colon tumor cell growth by activating the cGMP/PKG pathway to suppress Wnt/β-catenin signaling. Mol Cancer Ther. 2013 Sep;12(9):1848-59. PMID: 23804703.

 

Li X, Gao L, Cui Q, et al. Sulindac inhibits tumor cell invasion by suppressing NF-κB-mediated transcription of microRNAs. Oncogene. 2012 Nov 29;31(48):4979-86. PMID: 22286762.

 

Scheper MA, Nikitakis NG, Chaisuparat R, et al. Sulindac induces apoptosis and inhibits tumor growth in vivo in head and neck squamous cell carcinoma. Neoplasia. 2007 Mar;9(3):192-9. PMID: 17401459.

" Xn Not dangerous goods.

LKT S8146 Sulindac Sulfone 500 mg 576.6 NSAID; COX-1/2 and PDE inhibitor. 5-Fluoro-2-methy l-1-((4-(methylsulfonyl) phenyl)- methylene)-1H-indene-3-acetic acid 59864-04-9 ≥98% 372.41 C20H17FO4S CC1=C(C2=C(C1=CC3=CC=C(C=C3)S(=O)(=O)C)C=CC(=C2)F)CC(=O)O Ambient Ambient Soluble in DMSO or ethanol. "Modi JP, Gharibani PM, Ma Z, et al. Protective mechanism of sulindac in an animal model of ischemic stroke. Brain Res. 2014 Aug 12;1576:91-9. PMID: 24968090.

 

Li N, Xi Y, Tinsley HN, et al. Sulindac selectively inhibits colon tumor cell growth by activating the cGMP/PKG pathway to suppress Wnt/β-catenin signaling. Mol Cancer Ther. 2013 Sep;12(9):1848-59. PMID: 23804703.

 

Li X, Gao L, Cui Q, et al. Sulindac inhibits tumor cell invasion by suppressing NF-κB-mediated transcription of microRNAs. Oncogene. 2012 Nov 29;31(48):4979-86. PMID: 22286762.

 

Scheper MA, Nikitakis NG, Chaisuparat R, et al. Sulindac induces apoptosis and inhibits tumor growth in vivo in head and neck squamous cell carcinoma. Neoplasia. 2007 Mar;9(3):192-9. PMID: 17401459.

" Not dangerous goods.

LKT S8145 Sulindac 25 g 206 NSAID; COX-1/2 and PDE inhibitor. (Z)-5-Fluoro-2-methyl-1-((p-(methylsulfinyl) phenyl)methylene)-1H-indene-3-acetic acid  Arthrocine; Sulindac sulfoxide; Clinoril; Clisundac; Reumofil 38194-50-2 ≥98% 356.42 C20H17FO3S CC1=C(C2=C(C1=CC3=CC=C(C=C3)S(=O)C)C=CC(=C2)F)CC(=O)O Ambient Ambient Soluble in DMSO (100 mM) or ethanol (25 mM). "Modi JP, Gharibani PM, Ma Z, et al. Protective mechanism of sulindac in an animal model of ischemic stroke. Brain Res. 2014 Aug 12;1576:91-9. PMID: 24968090.

 

Li N, Xi Y, Tinsley HN, et al. Sulindac selectively inhibits colon tumor cell growth by activating the cGMP/PKG pathway to suppress Wnt/β-catenin signaling. Mol Cancer Ther. 2013 Sep;12(9):1848-59. PMID: 23804703.

 

Li X, Gao L, Cui Q, et al. Sulindac inhibits tumor cell invasion by suppressing NF-κB-mediated transcription of microRNAs. Oncogene. 2012 Nov 29;31(48):4979-86. PMID: 22286762.

 

Scheper MA, Nikitakis NG, Chaisuparat R, et al. Sulindac induces apoptosis and inhibits tumor growth in vivo in head and neck squamous cell carcinoma. Neoplasia. 2007 Mar;9(3):192-9. PMID: 17401459.

" Xn "UN number: 2811     Class:  6.1     Packing group:  III

Proper shipping name:  Toxic solids, organic, n.o.s. (Sulindac)

Marine pollutant:  No     Poison inhalation hazard:  No"

LKT S8144 Sulfadoxine 10 g 81 Sulfonamide; dihydropteroate synthase inhibitor. 4-Amino-N-(5,6-dimethoxy-4-pyrimidinyl)- benzenesulfonamide Fanasil; Fanzil; Sulforthomidine 2447-57-6 ≥98% 310.33 C12H14N4O4S COC1=C(N=CN=C1OC)NS(=O)(=O)C2=CC=C(C=C2)N Ambient Ambient Soluble in dilute mineral acids, solutions of alkali hydroxides and carbonates. Slightly soluble in water and methanol. "Combrinck JM, Mabotha TE, Ncokazi KK, et al. Insights into the role of heme in the mechanism of action of antimalarials. ACS Chem Biol. 2013 Jan 18;8(1):133-7. PMID: 23043646.

 

Abebe W. Therapeutic efficacy of sulfadoxin/pyrimethamine in the treatment of uncomplicated Plasmodium falciparum malaria in Enseno, Meskan Woreda, Gurage zone, SNNPR, Ethiopia. Ethiop Med J. 2006 Apr;44(2):133-8. PMID: 17447375.

" Xi Not dangerous goods.

LKT S8144 Sulfadoxine 25 g 173.3 Sulfonamide; dihydropteroate synthase inhibitor. 4-Amino-N-(5,6-dimethoxy-4-pyrimidinyl)- benzenesulfonamide Fanasil; Fanzil; Sulforthomidine 2447-57-6 ≥98% 310.33 C12H14N4O4S COC1=C(N=CN=C1OC)NS(=O)(=O)C2=CC=C(C=C2)N Ambient Ambient Soluble in dilute mineral acids, solutions of alkali hydroxides and carbonates. Slightly soluble in water and methanol. "Combrinck JM, Mabotha TE, Ncokazi KK, et al. Insights into the role of heme in the mechanism of action of antimalarials. ACS Chem Biol. 2013 Jan 18;8(1):133-7. PMID: 23043646.

 

Abebe W. Therapeutic efficacy of sulfadoxin/pyrimethamine in the treatment of uncomplicated Plasmodium falciparum malaria in Enseno, Meskan Woreda, Gurage zone, SNNPR, Ethiopia. Ethiop Med J. 2006 Apr;44(2):133-8. PMID: 17447375.

" Xi Not dangerous goods.

LKT S8144 Sulfadoxine 100 g 462.1 Sulfonamide; dihydropteroate synthase inhibitor. 4-Amino-N-(5,6-dimethoxy-4-pyrimidinyl)- benzenesulfonamide Fanasil; Fanzil; Sulforthomidine 2447-57-6 ≥98% 310.33 C12H14N4O4S COC1=C(N=CN=C1OC)NS(=O)(=O)C2=CC=C(C=C2)N Ambient Ambient Soluble in dilute mineral acids, solutions of alkali hydroxides and carbonates. Slightly soluble in water and methanol. "Combrinck JM, Mabotha TE, Ncokazi KK, et al. Insights into the role of heme in the mechanism of action of antimalarials. ACS Chem Biol. 2013 Jan 18;8(1):133-7. PMID: 23043646.

 

Abebe W. Therapeutic efficacy of sulfadoxin/pyrimethamine in the treatment of uncomplicated Plasmodium falciparum malaria in Enseno, Meskan Woreda, Gurage zone, SNNPR, Ethiopia. Ethiop Med J. 2006 Apr;44(2):133-8. PMID: 17447375.

" Xi Not dangerous goods.

LKT S8110 Sucralfate 1 g 65.6 Antacid; pepsin inhibitor. Assay (Polysaccharide sulfate) 30-38% Sucrose Octasulfate-Aluminum Complex 54182-58-0 Assay (Polysaccharide sulfate) 30-38% 974.73 C12H54Al16O75S8 Ambient Ambient Dilute HCl, NaH2O2 "Pali-Schöll I, Yildirim AO, Ackermann U, et al. Anti-acids lead to immunological and morphological changes in the intestine of BALB/c mice similar to human food allergy. Exp Toxicol Pathol. 2008 Aug;60(4-5):337-45. PMID: 18524557.

 

Shindo K, Iizuka M, Sasaki K, et al. Sucralfate prevents the delay of wound repair in intestinal epithelial cells by hydrogen peroxide through NF-kappaB pathway. J Gastroenterol. 2006 May;41(5):450-61. PMID: 16799887.

 

Furukawa O, Matsui H, Suzuki N. Effects of sucralfate and its components on acid- and pepsin-induced damage to rat gastric epithelial cells. Jpn J Pharmacol. 1997 Sep;75(1):21-5. PMID: 9334882.

 

Banerjee S, El-Omar E, Mowat A, et al. Sucralfate suppresses Helicobacter pylori infection and reduces gastric acid secretion by 50% in patients with duodenal ulcer. Gastroenterology. 1996 Mar;110(3):717-24. PMID: 8608880.

 

Tarnawski A, Hollander D, Gergely H. The mechanism of protective, therapeutic and prophylactic actions of sucralfate. Scand J Gastroenterol Suppl. 1987;140:7-13. PMID: 3481883.

" Not dangerous goods.

LKT S8110 Sucralfate 5 g 225 Antacid; pepsin inhibitor. Assay (Polysaccharide sulfate) 30-38% Sucrose Octasulfate-Aluminum Complex 54182-58-0 Assay (Polysaccharide sulfate) 30-38% 974.73 C12H54Al16O75S8 Ambient Ambient Dilute HCl, NaH2O2 "Pali-Schöll I, Yildirim AO, Ackermann U, et al. Anti-acids lead to immunological and morphological changes in the intestine of BALB/c mice similar to human food allergy. Exp Toxicol Pathol. 2008 Aug;60(4-5):337-45. PMID: 18524557.

 

Shindo K, Iizuka M, Sasaki K, et al. Sucralfate prevents the delay of wound repair in intestinal epithelial cells by hydrogen peroxide through NF-kappaB pathway. J Gastroenterol. 2006 May;41(5):450-61. PMID: 16799887.

 

Furukawa O, Matsui H, Suzuki N. Effects of sucralfate and its components on acid- and pepsin-induced damage to rat gastric epithelial cells. Jpn J Pharmacol. 1997 Sep;75(1):21-5. PMID: 9334882.

 

Banerjee S, El-Omar E, Mowat A, et al. Sucralfate suppresses Helicobacter pylori infection and reduces gastric acid secretion by 50% in patients with duodenal ulcer. Gastroenterology. 1996 Mar;110(3):717-24. PMID: 8608880.

 

Tarnawski A, Hollander D, Gergely H. The mechanism of protective, therapeutic and prophylactic actions of sucralfate. Scand J Gastroenterol Suppl. 1987;140:7-13. PMID: 3481883.

" Not dangerous goods.

LKT S8049 S-Sulforaphene 25 mg 498.8 ITC found in cruciferous vegetables. (-)4-Isothiocyanato-4R-(methylsulfinyl)-1-butene Raphanin; Sativin 592-95-0 ≥98% 175.27 C6H9NOS2 CS(=O)C=CCCN=C=S Ambient -20°C Soluble in water, methanol, DMSO, or chloroform. "Kim KH, Moon E, Kim SY, et al. 4-Methylthio-butanyl derivatives from the seeds of Raphanus sativus and their biological evaluation on anti-inflammatory and antitumor activities. J Ethnopharmacol. 2014;151(1):503-8. PMID: 24231071.

 

Beevi SS, Mangamoori LN, Subathra M, et al. Hexane extract of Raphanus sativus L. roots inhibits cell proliferation and induces apoptosis in human cancer cells by modulating genes related to apoptotic pathway. Plant Foods Hum Nutr. 2010 Sep;65(3):200-9. PMID: 20652750.

 

Brinker AM, Spencer GF. Herbicidal activity of sulforaphene from stock (Matthiola incana). J Chem Ecol. 1993 Oct;19(10):2279-84. PMID: 24248575.

" Not dangerous goods.

LKT S8049 S-Sulforaphene 50 mg 971.3 ITC found in cruciferous vegetables. (-)4-Isothiocyanato-4R-(methylsulfinyl)-1-butene Raphanin; Sativin 592-95-0 ≥98% 175.27 C6H9NOS2 CS(=O)C=CCCN=C=S Ambient -20°C Soluble in water, methanol, DMSO, or chloroform. "Kim KH, Moon E, Kim SY, et al. 4-Methylthio-butanyl derivatives from the seeds of Raphanus sativus and their biological evaluation on anti-inflammatory and antitumor activities. J Ethnopharmacol. 2014;151(1):503-8. PMID: 24231071.

 

Beevi SS, Mangamoori LN, Subathra M, et al. Hexane extract of Raphanus sativus L. roots inhibits cell proliferation and induces apoptosis in human cancer cells by modulating genes related to apoptotic pathway. Plant Foods Hum Nutr. 2010 Sep;65(3):200-9. PMID: 20652750.

 

Brinker AM, Spencer GF. Herbicidal activity of sulforaphene from stock (Matthiola incana). J Chem Ecol. 1993 Oct;19(10):2279-84. PMID: 24248575.

" Not dangerous goods.

LKT S8046 R-Sulforaphane 50 mg 866.3 ITC found in cruciferous vegetables; AhR antagonist. 1-Isothiocyanato-4-(methylsulfinyl)-butane L-Sulforaphane 142825-10-3 ≥98% 177.29 C6H11NOS2 CS(=O)CCCCN=C=S Ambient -20°C Soluble in ethanol,  methanol, or ethyl acetate.  Miscible with  water and/or DMSO. "Abdull Razis AF, Hanlon N, Soltys E, et al. The naturally occurring aliphatic isothiocyanates sulforaphane and erucin are weak agonists but potent non-competitive antagonists of the aryl hydrocarbon receptor. Arch Toxicol. 2012 Oct;86(10):1505-14. PMID: 22643862.

 

Zanichelli F, Capasso S, Cipollaro M, et al. Dose-dependent effects of R-sulforaphane isothiocyanate on the biology of human mesenchymal stem cells, at dietary amounts, it promotes cell proliferation and reduces senescence and apoptosis, while at anti-cancer drug doses, it has a cytotoxic effect. Age (Dordr). 2012 Apr;34(2):281-93. PMID: 21465338.

 

Abdull Razis AF, Bagatta M, De Nicola GR, et al. Induction of epoxide hydrolase and glucuronosyl transferase by isothiocyanates and intact glucosinolates in precision-cut rat liver slices: importance of side-chain substituent and chirality. Arch Toxicol. 2011 Aug;85(8):919-27. PMID: 21132492.

 

Abdull Razis AF, Iori R, Ioannides C. The natural chemopreventive phytochemical R-sulforaphane is a far more potent inducer of the carcinogen-detoxifying enzyme systems in rat liver and lung than the S-isomer. Int J Cancer. 2011 Jun 15;128(12):2775-82. PMID: 20726001.

" Not dangerous goods.

LKT S8013 [Tyr8]-Substance P 1 mg 96 Endogenous tachykinin peptide, involved in inflammation, stress signaling, nociception; NK1 agonist. 55614-10-3 ≥95% 1363.66 C63H98N18O14S1 CC(C)CC(C(=O)NC(CCSC)C(=O)N)NC(=O)CNC(=O)C(CC1=CC=C(C=C1)O)NC(=O)C(CC2=CC=CC=C2)NC(=O)C(CCC(=O)N)NC(=O)C(CCC(=O)N)NC(=O)C3CCCN3C(=O)C(CCCCN)NC(=O)C4CCCN4C(=O)C(CCCN=C(N)N)N Ambient -20°C "Yang L, Liu C, Dang H, et al. Substance P attenuates hyperoxia induced lung injury in neonatal rats. Mol Med Rep. 2014 Feb;9(2):595-9. PMID: 24247295.

 

Campolongo P, Ratano P, Ciotti MT, et al. Systemic administration of substance P recovers beta amyloid-induced cognitive deficits in rat: involvement of Kv potassium channels. PLoS One. 2013 Nov 12;8(11):e78036. PMID: 24265678.

 

Yang JH, Guo Z, Zhang T, et al. Restoration of endogenous substance P is associated with inhibition of apoptosis of retinal cells in diabetic rats. Regul Pept. 2013 Nov 10;187:12-6. PMID: 24045094.

 

Ma W, Zhang X, Shi S, et al. Neuropeptides stimulate human osteoblast activity and promote gap junctional intercellular communication. Neuropeptides. 2013 Jun;47(3):179-86. PMID: 23726661.

 

Brancati SB, Zádori ZS, Németh J, et al. Substance P induces gastric mucosal protection at supraspinal level via increasing the level of endomorphin-2 in rats. Brain Res Bull. 2013 Feb;91:38-45. PMID: 23328537.

 

Ping F, Shang J, Zhou J, et al. Activation of neurokinin-1 receptor by substance P inhibits melanogenesis in B16-F10 melanoma cells. Int J Biochem Cell Biol. 2012 Dec;44(12):2342-8. PMID: 23041339.

" Not dangerous goods.

LKT S8013 [Tyr8]-Substance P 2 mg 162 Endogenous tachykinin peptide, involved in inflammation, stress signaling, nociception; NK1 agonist. 55614-10-3 ≥95% 1363.66 C63H98N18O14S1 CC(C)CC(C(=O)NC(CCSC)C(=O)N)NC(=O)CNC(=O)C(CC1=CC=C(C=C1)O)NC(=O)C(CC2=CC=CC=C2)NC(=O)C(CCC(=O)N)NC(=O)C(CCC(=O)N)NC(=O)C3CCCN3C(=O)C(CCCCN)NC(=O)C4CCCN4C(=O)C(CCCN=C(N)N)N Ambient -20°C "Yang L, Liu C, Dang H, et al. Substance P attenuates hyperoxia induced lung injury in neonatal rats. Mol Med Rep. 2014 Feb;9(2):595-9. PMID: 24247295.

 

Campolongo P, Ratano P, Ciotti MT, et al. Systemic administration of substance P recovers beta amyloid-induced cognitive deficits in rat: involvement of Kv potassium channels. PLoS One. 2013 Nov 12;8(11):e78036. PMID: 24265678.

 

Yang JH, Guo Z, Zhang T, et al. Restoration of endogenous substance P is associated with inhibition of apoptosis of retinal cells in diabetic rats. Regul Pept. 2013 Nov 10;187:12-6. PMID: 24045094.

 

Ma W, Zhang X, Shi S, et al. Neuropeptides stimulate human osteoblast activity and promote gap junctional intercellular communication. Neuropeptides. 2013 Jun;47(3):179-86. PMID: 23726661.

 

Brancati SB, Zádori ZS, Németh J, et al. Substance P induces gastric mucosal protection at supraspinal level via increasing the level of endomorphin-2 in rats. Brain Res Bull. 2013 Feb;91:38-45. PMID: 23328537.

 

Ping F, Shang J, Zhou J, et al. Activation of neurokinin-1 receptor by substance P inhibits melanogenesis in B16-F10 melanoma cells. Int J Biochem Cell Biol. 2012 Dec;44(12):2342-8. PMID: 23041339.

" Not dangerous goods.

LKT S8013 [Tyr8]-Substance P 5 mg 287.9 Endogenous tachykinin peptide, involved in inflammation, stress signaling, nociception; NK1 agonist. 55614-10-3 ≥95% 1363.66 C63H98N18O14S1 CC(C)CC(C(=O)NC(CCSC)C(=O)N)NC(=O)CNC(=O)C(CC1=CC=C(C=C1)O)NC(=O)C(CC2=CC=CC=C2)NC(=O)C(CCC(=O)N)NC(=O)C(CCC(=O)N)NC(=O)C3CCCN3C(=O)C(CCCCN)NC(=O)C4CCCN4C(=O)C(CCCN=C(N)N)N Ambient -20°C "Yang L, Liu C, Dang H, et al. Substance P attenuates hyperoxia induced lung injury in neonatal rats. Mol Med Rep. 2014 Feb;9(2):595-9. PMID: 24247295.

 

Campolongo P, Ratano P, Ciotti MT, et al. Systemic administration of substance P recovers beta amyloid-induced cognitive deficits in rat: involvement of Kv potassium channels. PLoS One. 2013 Nov 12;8(11):e78036. PMID: 24265678.

 

Yang JH, Guo Z, Zhang T, et al. Restoration of endogenous substance P is associated with inhibition of apoptosis of retinal cells in diabetic rats. Regul Pept. 2013 Nov 10;187:12-6. PMID: 24045094.

 

Ma W, Zhang X, Shi S, et al. Neuropeptides stimulate human osteoblast activity and promote gap junctional intercellular communication. Neuropeptides. 2013 Jun;47(3):179-86. PMID: 23726661.

 

Brancati SB, Zádori ZS, Németh J, et al. Substance P induces gastric mucosal protection at supraspinal level via increasing the level of endomorphin-2 in rats. Brain Res Bull. 2013 Feb;91:38-45. PMID: 23328537.

 

Ping F, Shang J, Zhou J, et al. Activation of neurokinin-1 receptor by substance P inhibits melanogenesis in B16-F10 melanoma cells. Int J Biochem Cell Biol. 2012 Dec;44(12):2342-8. PMID: 23041339.

" Not dangerous goods.

LKT S8012 [Sar9]-Substance P 1 mg 83.9 Endogenous tachykinin peptide, involved in inflammation, stress signaling, nociception; NK1 agonist. 77128-75-7 ≥95% 1361.61 C64H100N18O13S CC(C)CC(C(=O)NC(CCSC)C(=O)N)NC(=O)CN(C)C(=O)C(CC1=CC=CC=C1)NC(=O)C(CC2=CC=CC=C2)NC(=O)C(CCC(=O)N)NC(=O)C(CCC(=O)N)NC(=O)C3CCCN3C(=O)C(CCCCN)NC(=O)C4CCCN4C(=O)C(CCCN=C(N)N)N Ambient -20°C "Yang L, Liu C, Dang H, et al. Substance P attenuates hyperoxia induced lung injury in neonatal rats. Mol Med Rep. 2014 Feb;9(2):595-9. PMID: 24247295.

 

Campolongo P, Ratano P, Ciotti MT, et al. Systemic administration of substance P recovers beta amyloid-induced cognitive deficits in rat: involvement of Kv potassium channels. PLoS One. 2013 Nov 12;8(11):e78036. PMID: 24265678.

 

Yang JH, Guo Z, Zhang T, et al. Restoration of endogenous substance P is associated with inhibition of apoptosis of retinal cells in diabetic rats. Regul Pept. 2013 Nov 10;187:12-6. PMID: 24045094.

 

Ma W, Zhang X, Shi S, et al. Neuropeptides stimulate human osteoblast activity and promote gap junctional intercellular communication. Neuropeptides. 2013 Jun;47(3):179-86. PMID: 23726661.

 

Brancati SB, Zádori ZS, Németh J, et al. Substance P induces gastric mucosal protection at supraspinal level via increasing the level of endomorphin-2 in rats. Brain Res Bull. 2013 Feb;91:38-45. PMID: 23328537.

 

Ping F, Shang J, Zhou J, et al. Activation of neurokinin-1 receptor by substance P inhibits melanogenesis in B16-F10 melanoma cells. Int J Biochem Cell Biol. 2012 Dec;44(12):2342-8. PMID: 23041339.

" Not dangerous goods.

LKT S8012 [Sar9]-Substance P 2 mg 144 Endogenous tachykinin peptide, involved in inflammation, stress signaling, nociception; NK1 agonist. 77128-75-7 ≥95% 1361.61 C64H100N18O13S CC(C)CC(C(=O)NC(CCSC)C(=O)N)NC(=O)CN(C)C(=O)C(CC1=CC=CC=C1)NC(=O)C(CC2=CC=CC=C2)NC(=O)C(CCC(=O)N)NC(=O)C(CCC(=O)N)NC(=O)C3CCCN3C(=O)C(CCCCN)NC(=O)C4CCCN4C(=O)C(CCCN=C(N)N)N Ambient -20°C "Yang L, Liu C, Dang H, et al. Substance P attenuates hyperoxia induced lung injury in neonatal rats. Mol Med Rep. 2014 Feb;9(2):595-9. PMID: 24247295.

 

Campolongo P, Ratano P, Ciotti MT, et al. Systemic administration of substance P recovers beta amyloid-induced cognitive deficits in rat: involvement of Kv potassium channels. PLoS One. 2013 Nov 12;8(11):e78036. PMID: 24265678.

 

Yang JH, Guo Z, Zhang T, et al. Restoration of endogenous substance P is associated with inhibition of apoptosis of retinal cells in diabetic rats. Regul Pept. 2013 Nov 10;187:12-6. PMID: 24045094.

 

Ma W, Zhang X, Shi S, et al. Neuropeptides stimulate human osteoblast activity and promote gap junctional intercellular communication. Neuropeptides. 2013 Jun;47(3):179-86. PMID: 23726661.

 

Brancati SB, Zádori ZS, Németh J, et al. Substance P induces gastric mucosal protection at supraspinal level via increasing the level of endomorphin-2 in rats. Brain Res Bull. 2013 Feb;91:38-45. PMID: 23328537.

 

Ping F, Shang J, Zhou J, et al. Activation of neurokinin-1 receptor by substance P inhibits melanogenesis in B16-F10 melanoma cells. Int J Biochem Cell Biol. 2012 Dec;44(12):2342-8. PMID: 23041339.

" Not dangerous goods.

LKT S8012 [Sar9]-Substance P 5 mg 252.1 Endogenous tachykinin peptide, involved in inflammation, stress signaling, nociception; NK1 agonist. 77128-75-7 ≥95% 1361.61 C64H100N18O13S CC(C)CC(C(=O)NC(CCSC)C(=O)N)NC(=O)CN(C)C(=O)C(CC1=CC=CC=C1)NC(=O)C(CC2=CC=CC=C2)NC(=O)C(CCC(=O)N)NC(=O)C(CCC(=O)N)NC(=O)C3CCCN3C(=O)C(CCCCN)NC(=O)C4CCCN4C(=O)C(CCCN=C(N)N)N Ambient -20°C "Yang L, Liu C, Dang H, et al. Substance P attenuates hyperoxia induced lung injury in neonatal rats. Mol Med Rep. 2014 Feb;9(2):595-9. PMID: 24247295.

 

Campolongo P, Ratano P, Ciotti MT, et al. Systemic administration of substance P recovers beta amyloid-induced cognitive deficits in rat: involvement of Kv potassium channels. PLoS One. 2013 Nov 12;8(11):e78036. PMID: 24265678.

 

Yang JH, Guo Z, Zhang T, et al. Restoration of endogenous substance P is associated with inhibition of apoptosis of retinal cells in diabetic rats. Regul Pept. 2013 Nov 10;187:12-6. PMID: 24045094.

 

Ma W, Zhang X, Shi S, et al. Neuropeptides stimulate human osteoblast activity and promote gap junctional intercellular communication. Neuropeptides. 2013 Jun;47(3):179-86. PMID: 23726661.

 

Brancati SB, Zádori ZS, Németh J, et al. Substance P induces gastric mucosal protection at supraspinal level via increasing the level of endomorphin-2 in rats. Brain Res Bull. 2013 Feb;91:38-45. PMID: 23328537.

 

Ping F, Shang J, Zhou J, et al. Activation of neurokinin-1 receptor by substance P inhibits melanogenesis in B16-F10 melanoma cells. Int J Biochem Cell Biol. 2012 Dec;44(12):2342-8. PMID: 23041339.

" Not dangerous goods.

LKT S8011 [Pro9]-Substance P 0.5 mg 60 Endogenous tachykinin peptide, involved in inflammation, stress signaling, nociception; NK1 agonist. 104486-69-3 ≥95% 1387.73 C66H102N18O13S CC(C)CC(C(=O)NC(CCSC)C(=O)N)NC(=O)C1CCCN1C(=O)C(CC2=CC=CC=C2)NC(=O)C(CC3=CC=CC=C3)NC(=O)C(CCC(=O)N)NC(=O)C(CCC(=O)N)NC(=O)C4CCCN4C(=O)C(CCCCN)NC(=O)C5CCCN5C(=O)C(CCCN=C(N)N)N Ambient -20°C Not dangerous goods.

LKT S8011 [Pro9]-Substance P 1 mg 101.9 Endogenous tachykinin peptide, involved in inflammation, stress signaling, nociception; NK1 agonist. 104486-69-3 ≥95% 1387.73 C66H102N18O13S CC(C)CC(C(=O)NC(CCSC)C(=O)N)NC(=O)C1CCCN1C(=O)C(CC2=CC=CC=C2)NC(=O)C(CC3=CC=CC=C3)NC(=O)C(CCC(=O)N)NC(=O)C(CCC(=O)N)NC(=O)C4CCCN4C(=O)C(CCCCN)NC(=O)C5CCCN5C(=O)C(CCCN=C(N)N)N Ambient -20°C Not dangerous goods.

LKT S8011 [Pro9]-Substance P 2.5 mg 180 Endogenous tachykinin peptide, involved in inflammation, stress signaling, nociception; NK1 agonist. 104486-69-3 ≥95% 1387.73 C66H102N18O13S CC(C)CC(C(=O)NC(CCSC)C(=O)N)NC(=O)C1CCCN1C(=O)C(CC2=CC=CC=C2)NC(=O)C(CC3=CC=CC=C3)NC(=O)C(CCC(=O)N)NC(=O)C(CCC(=O)N)NC(=O)C4CCCN4C(=O)C(CCCCN)NC(=O)C5CCCN5C(=O)C(CCCN=C(N)N)N Ambient -20°C Not dangerous goods.

LKT S8010 [Nle11]-Substance P 1 mg 60 Endogenous tachykinin peptide, involved in inflammation, stress signaling, nociception; NK1 agonist. 57462-42-7 ≥95% 1329.62 C64H100N18O13 CCCCC(C(=O)N)NC(=O)C(CC(C)C)NC(=O)CNC(=O)C(CC1=CC=CC=C1)NC(=O)C(CC2=CC=CC=C2)NC(=O)C(CCC(=O)N)NC(=O)C(CCC(=O)N)NC(=O)C3CCCN3C(=O)C(CCCCN)NC(=O)C4CCCN4C(=O)C(CCCN=C(N)N)N Ambient -20°C "Yang L, Liu C, Dang H, et al. Substance P attenuates hyperoxia induced lung injury in neonatal rats. Mol Med Rep. 2014 Feb;9(2):595-9. PMID: 24247295.

 

Campolongo P, Ratano P, Ciotti MT, et al. Systemic administration of substance P recovers beta amyloid-induced cognitive deficits in rat: involvement of Kv potassium channels. PLoS One. 2013 Nov 12;8(11):e78036. PMID: 24265678.

 

Yang JH, Guo Z, Zhang T, et al. Restoration of endogenous substance P is associated with inhibition of apoptosis of retinal cells in diabetic rats. Regul Pept. 2013 Nov 10;187:12-6. PMID: 24045094.

 

Ma W, Zhang X, Shi S, et al. Neuropeptides stimulate human osteoblast activity and promote gap junctional intercellular communication. Neuropeptides. 2013 Jun;47(3):179-86. PMID: 23726661.

 

Brancati SB, Zádori ZS, Németh J, et al. Substance P induces gastric mucosal protection at supraspinal level via increasing the level of endomorphin-2 in rats. Brain Res Bull. 2013 Feb;91:38-45. PMID: 23328537.

 

Ping F, Shang J, Zhou J, et al. Activation of neurokinin-1 receptor by substance P inhibits melanogenesis in B16-F10 melanoma cells. Int J Biochem Cell Biol. 2012 Dec;44(12):2342-8. PMID: 23041339.

" Not dangerous goods.

LKT S8010 [Nle11]-Substance P 2 mg 101.9 Endogenous tachykinin peptide, involved in inflammation, stress signaling, nociception; NK1 agonist. 57462-42-7 ≥95% 1329.62 C64H100N18O13 CCCCC(C(=O)N)NC(=O)C(CC(C)C)NC(=O)CNC(=O)C(CC1=CC=CC=C1)NC(=O)C(CC2=CC=CC=C2)NC(=O)C(CCC(=O)N)NC(=O)C(CCC(=O)N)NC(=O)C3CCCN3C(=O)C(CCCCN)NC(=O)C4CCCN4C(=O)C(CCCN=C(N)N)N Ambient -20°C "Yang L, Liu C, Dang H, et al. Substance P attenuates hyperoxia induced lung injury in neonatal rats. Mol Med Rep. 2014 Feb;9(2):595-9. PMID: 24247295.

 

Campolongo P, Ratano P, Ciotti MT, et al. Systemic administration of substance P recovers beta amyloid-induced cognitive deficits in rat: involvement of Kv potassium channels. PLoS One. 2013 Nov 12;8(11):e78036. PMID: 24265678.

 

Yang JH, Guo Z, Zhang T, et al. Restoration of endogenous substance P is associated with inhibition of apoptosis of retinal cells in diabetic rats. Regul Pept. 2013 Nov 10;187:12-6. PMID: 24045094.

 

Ma W, Zhang X, Shi S, et al. Neuropeptides stimulate human osteoblast activity and promote gap junctional intercellular communication. Neuropeptides. 2013 Jun;47(3):179-86. PMID: 23726661.

 

Brancati SB, Zádori ZS, Németh J, et al. Substance P induces gastric mucosal protection at supraspinal level via increasing the level of endomorphin-2 in rats. Brain Res Bull. 2013 Feb;91:38-45. PMID: 23328537.

 

Ping F, Shang J, Zhou J, et al. Activation of neurokinin-1 receptor by substance P inhibits melanogenesis in B16-F10 melanoma cells. Int J Biochem Cell Biol. 2012 Dec;44(12):2342-8. PMID: 23041339.

" Not dangerous goods.

LKT S8010 [Nle11]-Substance P 5 mg 180 Endogenous tachykinin peptide, involved in inflammation, stress signaling, nociception; NK1 agonist. 57462-42-7 ≥95% 1329.62 C64H100N18O13 CCCCC(C(=O)N)NC(=O)C(CC(C)C)NC(=O)CNC(=O)C(CC1=CC=CC=C1)NC(=O)C(CC2=CC=CC=C2)NC(=O)C(CCC(=O)N)NC(=O)C(CCC(=O)N)NC(=O)C3CCCN3C(=O)C(CCCCN)NC(=O)C4CCCN4C(=O)C(CCCN=C(N)N)N Ambient -20°C "Yang L, Liu C, Dang H, et al. Substance P attenuates hyperoxia induced lung injury in neonatal rats. Mol Med Rep. 2014 Feb;9(2):595-9. PMID: 24247295.

 

Campolongo P, Ratano P, Ciotti MT, et al. Systemic administration of substance P recovers beta amyloid-induced cognitive deficits in rat: involvement of Kv potassium channels. PLoS One. 2013 Nov 12;8(11):e78036. PMID: 24265678.

 

Yang JH, Guo Z, Zhang T, et al. Restoration of endogenous substance P is associated with inhibition of apoptosis of retinal cells in diabetic rats. Regul Pept. 2013 Nov 10;187:12-6. PMID: 24045094.

 

Ma W, Zhang X, Shi S, et al. Neuropeptides stimulate human osteoblast activity and promote gap junctional intercellular communication. Neuropeptides. 2013 Jun;47(3):179-86. PMID: 23726661.

 

Brancati SB, Zádori ZS, Németh J, et al. Substance P induces gastric mucosal protection at supraspinal level via increasing the level of endomorphin-2 in rats. Brain Res Bull. 2013 Feb;91:38-45. PMID: 23328537.

 

Ping F, Shang J, Zhou J, et al. Activation of neurokinin-1 receptor by substance P inhibits melanogenesis in B16-F10 melanoma cells. Int J Biochem Cell Biol. 2012 Dec;44(12):2342-8. PMID: 23041339.

" Not dangerous goods.

LKT S8009 Substance P (7-11) 1 mg 60 Endogenous tachykinin peptide, involved in inflammation, stress signaling, nociception; NK1 agonist. 51165-05-0 ≥95% 612.8 C31H44N6O5S1 CC(C)CC(C(=O)NC(CCSC)C(=O)N)NC(=O)CNC(=O)C(CC1=CC=CC=C1)NC(=O)C(CC2=CC=CC=C2)N Ambient -20°C "Yang L, Liu C, Dang H, et al. Substance P attenuates hyperoxia induced lung injury in neonatal rats. Mol Med Rep. 2014 Feb;9(2):595-9. PMID: 24247295.

 

Campolongo P, Ratano P, Ciotti MT, et al. Systemic administration of substance P recovers beta amyloid-induced cognitive deficits in rat: involvement of Kv potassium channels. PLoS One. 2013 Nov 12;8(11):e78036. PMID: 24265678.

 

Yang JH, Guo Z, Zhang T, et al. Restoration of endogenous substance P is associated with inhibition of apoptosis of retinal cells in diabetic rats. Regul Pept. 2013 Nov 10;187:12-6. PMID: 24045094.

 

Ma W, Zhang X, Shi S, et al. Neuropeptides stimulate human osteoblast activity and promote gap junctional intercellular communication. Neuropeptides. 2013 Jun;47(3):179-86. PMID: 23726661.

 

Brancati SB, Zádori ZS, Németh J, et al. Substance P induces gastric mucosal protection at supraspinal level via increasing the level of endomorphin-2 in rats. Brain Res Bull. 2013 Feb;91:38-45. PMID: 23328537.

 

Ping F, Shang J, Zhou J, et al. Activation of neurokinin-1 receptor by substance P inhibits melanogenesis in B16-F10 melanoma cells. Int J Biochem Cell Biol. 2012 Dec;44(12):2342-8. PMID: 23041339.

" Not dangerous goods.

LKT S8009 Substance P (7-11) 2 mg 101.9 Endogenous tachykinin peptide, involved in inflammation, stress signaling, nociception; NK1 agonist. 51165-05-0 ≥95% 612.8 C31H44N6O5S1 CC(C)CC(C(=O)NC(CCSC)C(=O)N)NC(=O)CNC(=O)C(CC1=CC=CC=C1)NC(=O)C(CC2=CC=CC=C2)N Ambient -20°C "Yang L, Liu C, Dang H, et al. Substance P attenuates hyperoxia induced lung injury in neonatal rats. Mol Med Rep. 2014 Feb;9(2):595-9. PMID: 24247295.

 

Campolongo P, Ratano P, Ciotti MT, et al. Systemic administration of substance P recovers beta amyloid-induced cognitive deficits in rat: involvement of Kv potassium channels. PLoS One. 2013 Nov 12;8(11):e78036. PMID: 24265678.

 

Yang JH, Guo Z, Zhang T, et al. Restoration of endogenous substance P is associated with inhibition of apoptosis of retinal cells in diabetic rats. Regul Pept. 2013 Nov 10;187:12-6. PMID: 24045094.

 

Ma W, Zhang X, Shi S, et al. Neuropeptides stimulate human osteoblast activity and promote gap junctional intercellular communication. Neuropeptides. 2013 Jun;47(3):179-86. PMID: 23726661.

 

Brancati SB, Zádori ZS, Németh J, et al. Substance P induces gastric mucosal protection at supraspinal level via increasing the level of endomorphin-2 in rats. Brain Res Bull. 2013 Feb;91:38-45. PMID: 23328537.

 

Ping F, Shang J, Zhou J, et al. Activation of neurokinin-1 receptor by substance P inhibits melanogenesis in B16-F10 melanoma cells. Int J Biochem Cell Biol. 2012 Dec;44(12):2342-8. PMID: 23041339.

" Not dangerous goods.

LKT S8009 Substance P (7-11) 5 mg 180 Endogenous tachykinin peptide, involved in inflammation, stress signaling, nociception; NK1 agonist. 51165-05-0 ≥95% 612.8 C31H44N6O5S1 CC(C)CC(C(=O)NC(CCSC)C(=O)N)NC(=O)CNC(=O)C(CC1=CC=CC=C1)NC(=O)C(CC2=CC=CC=C2)N Ambient -20°C "Yang L, Liu C, Dang H, et al. Substance P attenuates hyperoxia induced lung injury in neonatal rats. Mol Med Rep. 2014 Feb;9(2):595-9. PMID: 24247295.

 

Campolongo P, Ratano P, Ciotti MT, et al. Systemic administration of substance P recovers beta amyloid-induced cognitive deficits in rat: involvement of Kv potassium channels. PLoS One. 2013 Nov 12;8(11):e78036. PMID: 24265678.

 

Yang JH, Guo Z, Zhang T, et al. Restoration of endogenous substance P is associated with inhibition of apoptosis of retinal cells in diabetic rats. Regul Pept. 2013 Nov 10;187:12-6. PMID: 24045094.

 

Ma W, Zhang X, Shi S, et al. Neuropeptides stimulate human osteoblast activity and promote gap junctional intercellular communication. Neuropeptides. 2013 Jun;47(3):179-86. PMID: 23726661.

 

Brancati SB, Zádori ZS, Németh J, et al. Substance P induces gastric mucosal protection at supraspinal level via increasing the level of endomorphin-2 in rats. Brain Res Bull. 2013 Feb;91:38-45. PMID: 23328537.

 

Ping F, Shang J, Zhou J, et al. Activation of neurokinin-1 receptor by substance P inhibits melanogenesis in B16-F10 melanoma cells. Int J Biochem Cell Biol. 2012 Dec;44(12):2342-8. PMID: 23041339.

" Not dangerous goods.

LKT S8008 Substance P (1-9) 1 mg 60 Endogenous tachykinin peptide, involved in inflammation, stress signaling, nociception; NK1 agonist. 57468-17-4 ≥95% 1104.28 C52H77N15O12 C1CC(N(C1)C(=O)C(CCCN=C(N)N)N)C(=O)NC(CCCCN)C(=O)N2CCCC2C(=O)NC(CCC(=O)N)C(=O)NC(CCC(=O)N)C(=O)NC(CC3=CC=CC=C3)C(=O)NC(CC4=CC=CC=C4)C(=O)NCC(=O)O Ambient -20°C "Yang L, Liu C, Dang H, et al. Substance P attenuates hyperoxia induced lung injury in neonatal rats. Mol Med Rep. 2014 Feb;9(2):595-9. PMID: 24247295.

 

Campolongo P, Ratano P, Ciotti MT, et al. Systemic administration of substance P recovers beta amyloid-induced cognitive deficits in rat: involvement of Kv potassium channels. PLoS One. 2013 Nov 12;8(11):e78036. PMID: 24265678.

 

Yang JH, Guo Z, Zhang T, et al. Restoration of endogenous substance P is associated with inhibition of apoptosis of retinal cells in diabetic rats. Regul Pept. 2013 Nov 10;187:12-6. PMID: 24045094.

 

Ma W, Zhang X, Shi S, et al. Neuropeptides stimulate human osteoblast activity and promote gap junctional intercellular communication. Neuropeptides. 2013 Jun;47(3):179-86. PMID: 23726661.

 

Brancati SB, Zádori ZS, Németh J, et al. Substance P induces gastric mucosal protection at supraspinal level via increasing the level of endomorphin-2 in rats. Brain Res Bull. 2013 Feb;91:38-45. PMID: 23328537.

 

Ping F, Shang J, Zhou J, et al. Activation of neurokinin-1 receptor by substance P inhibits melanogenesis in B16-F10 melanoma cells. Int J Biochem Cell Biol. 2012 Dec;44(12):2342-8. PMID: 23041339.

" Not dangerous goods.

LKT S8008 Substance P (1-9) 2 mg 101.9 Endogenous tachykinin peptide, involved in inflammation, stress signaling, nociception; NK1 agonist. 57468-17-4 ≥95% 1104.28 C52H77N15O12 C1CC(N(C1)C(=O)C(CCCN=C(N)N)N)C(=O)NC(CCCCN)C(=O)N2CCCC2C(=O)NC(CCC(=O)N)C(=O)NC(CCC(=O)N)C(=O)NC(CC3=CC=CC=C3)C(=O)NC(CC4=CC=CC=C4)C(=O)NCC(=O)O Ambient -20°C "Yang L, Liu C, Dang H, et al. Substance P attenuates hyperoxia induced lung injury in neonatal rats. Mol Med Rep. 2014 Feb;9(2):595-9. PMID: 24247295.

 

Campolongo P, Ratano P, Ciotti MT, et al. Systemic administration of substance P recovers beta amyloid-induced cognitive deficits in rat: involvement of Kv potassium channels. PLoS One. 2013 Nov 12;8(11):e78036. PMID: 24265678.

 

Yang JH, Guo Z, Zhang T, et al. Restoration of endogenous substance P is associated with inhibition of apoptosis of retinal cells in diabetic rats. Regul Pept. 2013 Nov 10;187:12-6. PMID: 24045094.

 

Ma W, Zhang X, Shi S, et al. Neuropeptides stimulate human osteoblast activity and promote gap junctional intercellular communication. Neuropeptides. 2013 Jun;47(3):179-86. PMID: 23726661.

 

Brancati SB, Zádori ZS, Németh J, et al. Substance P induces gastric mucosal protection at supraspinal level via increasing the level of endomorphin-2 in rats. Brain Res Bull. 2013 Feb;91:38-45. PMID: 23328537.

 

Ping F, Shang J, Zhou J, et al. Activation of neurokinin-1 receptor by substance P inhibits melanogenesis in B16-F10 melanoma cells. Int J Biochem Cell Biol. 2012 Dec;44(12):2342-8. PMID: 23041339.

" Not dangerous goods.

LKT S8008 Substance P (1-9) 5 mg 180 Endogenous tachykinin peptide, involved in inflammation, stress signaling, nociception; NK1 agonist. 57468-17-4 ≥95% 1104.28 C52H77N15O12 C1CC(N(C1)C(=O)C(CCCN=C(N)N)N)C(=O)NC(CCCCN)C(=O)N2CCCC2C(=O)NC(CCC(=O)N)C(=O)NC(CCC(=O)N)C(=O)NC(CC3=CC=CC=C3)C(=O)NC(CC4=CC=CC=C4)C(=O)NCC(=O)O Ambient -20°C "Yang L, Liu C, Dang H, et al. Substance P attenuates hyperoxia induced lung injury in neonatal rats. Mol Med Rep. 2014 Feb;9(2):595-9. PMID: 24247295.

 

Campolongo P, Ratano P, Ciotti MT, et al. Systemic administration of substance P recovers beta amyloid-induced cognitive deficits in rat: involvement of Kv potassium channels. PLoS One. 2013 Nov 12;8(11):e78036. PMID: 24265678.

 

Yang JH, Guo Z, Zhang T, et al. Restoration of endogenous substance P is associated with inhibition of apoptosis of retinal cells in diabetic rats. Regul Pept. 2013 Nov 10;187:12-6. PMID: 24045094.

 

Ma W, Zhang X, Shi S, et al. Neuropeptides stimulate human osteoblast activity and promote gap junctional intercellular communication. Neuropeptides. 2013 Jun;47(3):179-86. PMID: 23726661.

 

Brancati SB, Zádori ZS, Németh J, et al. Substance P induces gastric mucosal protection at supraspinal level via increasing the level of endomorphin-2 in rats. Brain Res Bull. 2013 Feb;91:38-45. PMID: 23328537.

 

Ping F, Shang J, Zhou J, et al. Activation of neurokinin-1 receptor by substance P inhibits melanogenesis in B16-F10 melanoma cells. Int J Biochem Cell Biol. 2012 Dec;44(12):2342-8. PMID: 23041339.

" Not dangerous goods.

LKT S8007 Substance P (1-7) 1 mg 60 Endogenous tachykinin peptide, involved in inflammation, stress signaling, nociception; NK1 agonist. 68060-49-1 ≥95% 900.06 C41H65N13O10 C1CC(N(C1)C(=O)C(CCCN=C(N)N)N)C(=O)NC(CCCCN)C(=O)N2CCCC2C(=O)NC(CCC(=O)N)C(=O)NC(CCC(=O)N)C(=O)NC(CC3=CC=CC=C3)C(=O)O Ambient -20°C "Yang L, Liu C, Dang H, et al. Substance P attenuates hyperoxia induced lung injury in neonatal rats. Mol Med Rep. 2014 Feb;9(2):595-9. PMID: 24247295.

 

Campolongo P, Ratano P, Ciotti MT, et al. Systemic administration of substance P recovers beta amyloid-induced cognitive deficits in rat: involvement of Kv potassium channels. PLoS One. 2013 Nov 12;8(11):e78036. PMID: 24265678.

 

Yang JH, Guo Z, Zhang T, et al. Restoration of endogenous substance P is associated with inhibition of apoptosis of retinal cells in diabetic rats. Regul Pept. 2013 Nov 10;187:12-6. PMID: 24045094.

 

Ma W, Zhang X, Shi S, et al. Neuropeptides stimulate human osteoblast activity and promote gap junctional intercellular communication. Neuropeptides. 2013 Jun;47(3):179-86. PMID: 23726661.

 

Brancati SB, Zádori ZS, Németh J, et al. Substance P induces gastric mucosal protection at supraspinal level via increasing the level of endomorphin-2 in rats. Brain Res Bull. 2013 Feb;91:38-45. PMID: 23328537.

 

Ping F, Shang J, Zhou J, et al. Activation of neurokinin-1 receptor by substance P inhibits melanogenesis in B16-F10 melanoma cells. Int J Biochem Cell Biol. 2012 Dec;44(12):2342-8. PMID: 23041339.

" Not dangerous goods.

LKT S8007 Substance P (1-7) 2 mg 101.9 Endogenous tachykinin peptide, involved in inflammation, stress signaling, nociception; NK1 agonist. 68060-49-1 ≥95% 900.06 C41H65N13O10 C1CC(N(C1)C(=O)C(CCCN=C(N)N)N)C(=O)NC(CCCCN)C(=O)N2CCCC2C(=O)NC(CCC(=O)N)C(=O)NC(CCC(=O)N)C(=O)NC(CC3=CC=CC=C3)C(=O)O Ambient -20°C "Yang L, Liu C, Dang H, et al. Substance P attenuates hyperoxia induced lung injury in neonatal rats. Mol Med Rep. 2014 Feb;9(2):595-9. PMID: 24247295.

 

Campolongo P, Ratano P, Ciotti MT, et al. Systemic administration of substance P recovers beta amyloid-induced cognitive deficits in rat: involvement of Kv potassium channels. PLoS One. 2013 Nov 12;8(11):e78036. PMID: 24265678.

 

Yang JH, Guo Z, Zhang T, et al. Restoration of endogenous substance P is associated with inhibition of apoptosis of retinal cells in diabetic rats. Regul Pept. 2013 Nov 10;187:12-6. PMID: 24045094.

 

Ma W, Zhang X, Shi S, et al. Neuropeptides stimulate human osteoblast activity and promote gap junctional intercellular communication. Neuropeptides. 2013 Jun;47(3):179-86. PMID: 23726661.

 

Brancati SB, Zádori ZS, Németh J, et al. Substance P induces gastric mucosal protection at supraspinal level via increasing the level of endomorphin-2 in rats. Brain Res Bull. 2013 Feb;91:38-45. PMID: 23328537.

 

Ping F, Shang J, Zhou J, et al. Activation of neurokinin-1 receptor by substance P inhibits melanogenesis in B16-F10 melanoma cells. Int J Biochem Cell Biol. 2012 Dec;44(12):2342-8. PMID: 23041339.

" Not dangerous goods.

LKT S8007 Substance P (1-7) 5 mg 180 Endogenous tachykinin peptide, involved in inflammation, stress signaling, nociception; NK1 agonist. 68060-49-1 ≥95% 900.06 C41H65N13O10 C1CC(N(C1)C(=O)C(CCCN=C(N)N)N)C(=O)NC(CCCCN)C(=O)N2CCCC2C(=O)NC(CCC(=O)N)C(=O)NC(CCC(=O)N)C(=O)NC(CC3=CC=CC=C3)C(=O)O Ambient -20°C "Yang L, Liu C, Dang H, et al. Substance P attenuates hyperoxia induced lung injury in neonatal rats. Mol Med Rep. 2014 Feb;9(2):595-9. PMID: 24247295.

 

Campolongo P, Ratano P, Ciotti MT, et al. Systemic administration of substance P recovers beta amyloid-induced cognitive deficits in rat: involvement of Kv potassium channels. PLoS One. 2013 Nov 12;8(11):e78036. PMID: 24265678.

 

Yang JH, Guo Z, Zhang T, et al. Restoration of endogenous substance P is associated with inhibition of apoptosis of retinal cells in diabetic rats. Regul Pept. 2013 Nov 10;187:12-6. PMID: 24045094.

 

Ma W, Zhang X, Shi S, et al. Neuropeptides stimulate human osteoblast activity and promote gap junctional intercellular communication. Neuropeptides. 2013 Jun;47(3):179-86. PMID: 23726661.

 

Brancati SB, Zádori ZS, Németh J, et al. Substance P induces gastric mucosal protection at supraspinal level via increasing the level of endomorphin-2 in rats. Brain Res Bull. 2013 Feb;91:38-45. PMID: 23328537.

 

Ping F, Shang J, Zhou J, et al. Activation of neurokinin-1 receptor by substance P inhibits melanogenesis in B16-F10 melanoma cells. Int J Biochem Cell Biol. 2012 Dec;44(12):2342-8. PMID: 23041339.

" Not dangerous goods.

LKT M1605 Mebendazole 5 g 42 Benzimidazole; microtubule polymerization inhibitor. (5-Benzoyl-1H-benzimidazole-2-yl)carbamic acid methyl ester Mebendazol; Lomper; Noverme; Pantelmin 31431-39-7 ≥98% 295.29 C16H13N3O3 COC(=O)NC1=NC2=C(N1)C=C(C=C2)C(=O)C3=CC=CC=C3 Ambient Ambient Soluble in formic acid. Practically insoluble in water, ethanol, ether and chloroform. "Doudican NA, Byron SA, Pollock PM, et al. XIAP downregulation accompanies mebendazole growth inhibition in melanoma xenografts. Anticancer Drugs. 2013 Feb;24(2):181-8. PMID: 23059386.

 

Doudican N, Rodriguez A, Osman I, et al. Mebendazole induces apoptosis via Bcl-2 inactivation in chemoresistant melanoma cells. Mol Cancer Res. 2008 Aug;6(8):1308-15. PMID: 18667591.

 

El-On J. Benzimidazole treatment of cystic echinococcosis. Acta Trop. 2003 Feb;85(2):243-52. PMID: 12606103.

" Xn Not dangerous goods.

LKT S8006 Substance P (1-4) 1 mg 60 Endogenous tachykinin peptide, involved in inflammation, stress signaling, nociception; NK1 agonist. 69355-89-1 ≥95% 496.6 C22H40N8O5 C1CC(N(C1)C(=O)C(CCCN=C(N)N)N)C(=O)NC(CCCCN)C(=O)N2CCCC2C(=O)N Ambient -20°C "Yang L, Liu C, Dang H, et al. Substance P attenuates hyperoxia induced lung injury in neonatal rats. Mol Med Rep. 2014 Feb;9(2):595-9. PMID: 24247295.

 

Campolongo P, Ratano P, Ciotti MT, et al. Systemic administration of substance P recovers beta amyloid-induced cognitive deficits in rat: involvement of Kv potassium channels. PLoS One. 2013 Nov 12;8(11):e78036. PMID: 24265678.

 

Yang JH, Guo Z, Zhang T, et al. Restoration of endogenous substance P is associated with inhibition of apoptosis of retinal cells in diabetic rats. Regul Pept. 2013 Nov 10;187:12-6. PMID: 24045094.

 

Ma W, Zhang X, Shi S, et al. Neuropeptides stimulate human osteoblast activity and promote gap junctional intercellular communication. Neuropeptides. 2013 Jun;47(3):179-86. PMID: 23726661.

 

Brancati SB, Zádori ZS, Németh J, et al. Substance P induces gastric mucosal protection at supraspinal level via increasing the level of endomorphin-2 in rats. Brain Res Bull. 2013 Feb;91:38-45. PMID: 23328537.

 

Ping F, Shang J, Zhou J, et al. Activation of neurokinin-1 receptor by substance P inhibits melanogenesis in B16-F10 melanoma cells. Int J Biochem Cell Biol. 2012 Dec;44(12):2342-8. PMID: 23041339.

" Not dangerous goods.

LKT M1605 Mebendazole 25 g 58.8 Benzimidazole; microtubule polymerization inhibitor. (5-Benzoyl-1H-benzimidazole-2-yl)carbamic acid methyl ester Mebendazol; Lomper; Noverme; Pantelmin 31431-39-7 ≥98% 295.29 C16H13N3O3 COC(=O)NC1=NC2=C(N1)C=C(C=C2)C(=O)C3=CC=CC=C3 Ambient Ambient Soluble in formic acid. Practically insoluble in water, ethanol, ether and chloroform. "Doudican NA, Byron SA, Pollock PM, et al. XIAP downregulation accompanies mebendazole growth inhibition in melanoma xenografts. Anticancer Drugs. 2013 Feb;24(2):181-8. PMID: 23059386.

 

Doudican N, Rodriguez A, Osman I, et al. Mebendazole induces apoptosis via Bcl-2 inactivation in chemoresistant melanoma cells. Mol Cancer Res. 2008 Aug;6(8):1308-15. PMID: 18667591.

 

El-On J. Benzimidazole treatment of cystic echinococcosis. Acta Trop. 2003 Feb;85(2):243-52. PMID: 12606103.

" Xn Not dangerous goods.

LKT S8006 Substance P (1-4) 2 mg 101.9 Endogenous tachykinin peptide, involved in inflammation, stress signaling, nociception; NK1 agonist. 69355-89-1 ≥95% 496.6 C22H40N8O5 C1CC(N(C1)C(=O)C(CCCN=C(N)N)N)C(=O)NC(CCCCN)C(=O)N2CCCC2C(=O)N Ambient -20°C "Yang L, Liu C, Dang H, et al. Substance P attenuates hyperoxia induced lung injury in neonatal rats. Mol Med Rep. 2014 Feb;9(2):595-9. PMID: 24247295.

 

Campolongo P, Ratano P, Ciotti MT, et al. Systemic administration of substance P recovers beta amyloid-induced cognitive deficits in rat: involvement of Kv potassium channels. PLoS One. 2013 Nov 12;8(11):e78036. PMID: 24265678.

 

Yang JH, Guo Z, Zhang T, et al. Restoration of endogenous substance P is associated with inhibition of apoptosis of retinal cells in diabetic rats. Regul Pept. 2013 Nov 10;187:12-6. PMID: 24045094.

 

Ma W, Zhang X, Shi S, et al. Neuropeptides stimulate human osteoblast activity and promote gap junctional intercellular communication. Neuropeptides. 2013 Jun;47(3):179-86. PMID: 23726661.

 

Brancati SB, Zádori ZS, Németh J, et al. Substance P induces gastric mucosal protection at supraspinal level via increasing the level of endomorphin-2 in rats. Brain Res Bull. 2013 Feb;91:38-45. PMID: 23328537.

 

Ping F, Shang J, Zhou J, et al. Activation of neurokinin-1 receptor by substance P inhibits melanogenesis in B16-F10 melanoma cells. Int J Biochem Cell Biol. 2012 Dec;44(12):2342-8. PMID: 23041339.

" Not dangerous goods.

LKT S8006 Substance P (1-4) 5 mg 180 Endogenous tachykinin peptide, involved in inflammation, stress signaling, nociception; NK1 agonist. 69355-89-1 ≥95% 496.6 C22H40N8O5 C1CC(N(C1)C(=O)C(CCCN=C(N)N)N)C(=O)NC(CCCCN)C(=O)N2CCCC2C(=O)N Ambient -20°C "Yang L, Liu C, Dang H, et al. Substance P attenuates hyperoxia induced lung injury in neonatal rats. Mol Med Rep. 2014 Feb;9(2):595-9. PMID: 24247295.

 

Campolongo P, Ratano P, Ciotti MT, et al. Systemic administration of substance P recovers beta amyloid-induced cognitive deficits in rat: involvement of Kv potassium channels. PLoS One. 2013 Nov 12;8(11):e78036. PMID: 24265678.

 

Yang JH, Guo Z, Zhang T, et al. Restoration of endogenous substance P is associated with inhibition of apoptosis of retinal cells in diabetic rats. Regul Pept. 2013 Nov 10;187:12-6. PMID: 24045094.

 

Ma W, Zhang X, Shi S, et al. Neuropeptides stimulate human osteoblast activity and promote gap junctional intercellular communication. Neuropeptides. 2013 Jun;47(3):179-86. PMID: 23726661.

 

Brancati SB, Zádori ZS, Németh J, et al. Substance P induces gastric mucosal protection at supraspinal level via increasing the level of endomorphin-2 in rats. Brain Res Bull. 2013 Feb;91:38-45. PMID: 23328537.

 

Ping F, Shang J, Zhou J, et al. Activation of neurokinin-1 receptor by substance P inhibits melanogenesis in B16-F10 melanoma cells. Int J Biochem Cell Biol. 2012 Dec;44(12):2342-8. PMID: 23041339.

" Not dangerous goods.

LKT S8005 Substance P 5 mg 107.8 Endogenous tachykinin peptide, involved in inflammation, stress signaling, nociception; NK1 agonist. 33507-63-0 ≥95% 1347.66 C63H98N18O13S1 CC(C)CC(C(=O)NC(CCSC)C(=O)N)NC(=O)CNC(=O)C(CC1=CC=CC=C1)NC(=O)C(CC2=CC=CC=C2)NC(=O)C(CCC(=O)N)NC(=O)C(CCC(=O)N)NC(=O)C3CCCN3C(=O)C(CCCCN)NC(=O)C4CCCN4C(=O)C(CCCN=C(N)N)N Ambient -20°C "Yang L, Liu C, Dang H, et al. Substance P attenuates hyperoxia induced lung injury in neonatal rats. Mol Med Rep. 2014 Feb;9(2):595-9. PMID: 24247295.

 

Campolongo P, Ratano P, Ciotti MT, et al. Systemic administration of substance P recovers beta amyloid-induced cognitive deficits in rat: involvement of Kv potassium channels. PLoS One. 2013 Nov 12;8(11):e78036. PMID: 24265678.

 

Yang JH, Guo Z, Zhang T, et al. Restoration of endogenous substance P is associated with inhibition of apoptosis of retinal cells in diabetic rats. Regul Pept. 2013 Nov 10;187:12-6. PMID: 24045094.

 

Ma W, Zhang X, Shi S, et al. Neuropeptides stimulate human osteoblast activity and promote gap junctional intercellular communication. Neuropeptides. 2013 Jun;47(3):179-86. PMID: 23726661.

 

Brancati SB, Zádori ZS, Németh J, et al. Substance P induces gastric mucosal protection at supraspinal level via increasing the level of endomorphin-2 in rats. Brain Res Bull. 2013 Feb;91:38-45. PMID: 23328537.

 

Ping F, Shang J, Zhou J, et al. Activation of neurokinin-1 receptor by substance P inhibits melanogenesis in B16-F10 melanoma cells. Int J Biochem Cell Biol. 2012 Dec;44(12):2342-8. PMID: 23041339.

" Not dangerous goods.

LKT S8005 Substance P 10 mg 183 Endogenous tachykinin peptide, involved in inflammation, stress signaling, nociception; NK1 agonist. 33507-63-0 ≥95% 1347.66 C63H98N18O13S1 CC(C)CC(C(=O)NC(CCSC)C(=O)N)NC(=O)CNC(=O)C(CC1=CC=CC=C1)NC(=O)C(CC2=CC=CC=C2)NC(=O)C(CCC(=O)N)NC(=O)C(CCC(=O)N)NC(=O)C3CCCN3C(=O)C(CCCCN)NC(=O)C4CCCN4C(=O)C(CCCN=C(N)N)N Ambient -20°C "Yang L, Liu C, Dang H, et al. Substance P attenuates hyperoxia induced lung injury in neonatal rats. Mol Med Rep. 2014 Feb;9(2):595-9. PMID: 24247295.

 

Campolongo P, Ratano P, Ciotti MT, et al. Systemic administration of substance P recovers beta amyloid-induced cognitive deficits in rat: involvement of Kv potassium channels. PLoS One. 2013 Nov 12;8(11):e78036. PMID: 24265678.

 

Yang JH, Guo Z, Zhang T, et al. Restoration of endogenous substance P is associated with inhibition of apoptosis of retinal cells in diabetic rats. Regul Pept. 2013 Nov 10;187:12-6. PMID: 24045094.

 

Ma W, Zhang X, Shi S, et al. Neuropeptides stimulate human osteoblast activity and promote gap junctional intercellular communication. Neuropeptides. 2013 Jun;47(3):179-86. PMID: 23726661.

 

Brancati SB, Zádori ZS, Németh J, et al. Substance P induces gastric mucosal protection at supraspinal level via increasing the level of endomorphin-2 in rats. Brain Res Bull. 2013 Feb;91:38-45. PMID: 23328537.

 

Ping F, Shang J, Zhou J, et al. Activation of neurokinin-1 receptor by substance P inhibits melanogenesis in B16-F10 melanoma cells. Int J Biochem Cell Biol. 2012 Dec;44(12):2342-8. PMID: 23041339.

" Not dangerous goods.

LKT M1613 Medroxyprogesterone 17-Acetate 500 mg 51.8 Synthetic steroid used in HRT; PR, AR, glucocorticoid agonist, 3α-hydroxysteroid dehydrogenase inhibitor. 17-α-Acetoxy-6α-methylprogesterone MAP; Clinovir; Depo-Provera; Farlutal; Nidaxin; Oragest; Prodasone; Provera; Veramix 71-58-9 ≥98% 386.52 C24H34O4 CC1CC2C(CCC3(C2CCC3(C(=O)C)OC(=O)C)C)C4(C1=CC(=O)CC4)C Ambient -20°C Soluble in chloroform or acetone. "Schindler AE, Campagnoli C, Druckmann R, et al. Classification and pharmacology of progestins. Maturitas. 2008 Sep-Oct;61(1-2):171-80. PMID: 19434889.

 

Meyer L, Venard C, Schaeffer V, et al. The biological activity of 3alpha-hydroxysteroid oxido-reductase in the spinal cord regulates thermal and mechanical pain thresholds after sciatic nerve injury. Neurobiol Dis. 2008 Apr;30(1):30-41. PMID: 18291663.

 

Poulin R, Baker D, Poirier D, et al. Androgen and glucocorticoid receptor-mediated inhibition of cell proliferation by medroxyprogesterone acetate in ZR-75-1 human breast cancer cells. Breast Cancer Res Treat. 1989 Mar;13(2):161-72. PMID: 2525057.

" Carc., Repr. Not dangerous goods.

LKT M1613 Medroxyprogesterone 17-Acetate 1 g 86.4 Synthetic steroid used in HRT; PR, AR, glucocorticoid agonist, 3α-hydroxysteroid dehydrogenase inhibitor. 17-α-Acetoxy-6α-methylprogesterone MAP; Clinovir; Depo-Provera; Farlutal; Nidaxin; Oragest; Prodasone; Provera; Veramix 71-58-9 ≥98% 386.52 C24H34O4 CC1CC2C(CCC3(C2CCC3(C(=O)C)OC(=O)C)C)C4(C1=CC(=O)CC4)C Ambient -20°C Soluble in chloroform or acetone. "Schindler AE, Campagnoli C, Druckmann R, et al. Classification and pharmacology of progestins. Maturitas. 2008 Sep-Oct;61(1-2):171-80. PMID: 19434889.

 

Meyer L, Venard C, Schaeffer V, et al. The biological activity of 3alpha-hydroxysteroid oxido-reductase in the spinal cord regulates thermal and mechanical pain thresholds after sciatic nerve injury. Neurobiol Dis. 2008 Apr;30(1):30-41. PMID: 18291663.

 

Poulin R, Baker D, Poirier D, et al. Androgen and glucocorticoid receptor-mediated inhibition of cell proliferation by medroxyprogesterone acetate in ZR-75-1 human breast cancer cells. Breast Cancer Res Treat. 1989 Mar;13(2):161-72. PMID: 2525057.

" Carc., Repr. Not dangerous goods.

LKT S8005 Substance P 25 mg 324 Endogenous tachykinin peptide, involved in inflammation, stress signaling, nociception; NK1 agonist. 33507-63-0 ≥95% 1347.66 C63H98N18O13S1 CC(C)CC(C(=O)NC(CCSC)C(=O)N)NC(=O)CNC(=O)C(CC1=CC=CC=C1)NC(=O)C(CC2=CC=CC=C2)NC(=O)C(CCC(=O)N)NC(=O)C(CCC(=O)N)NC(=O)C3CCCN3C(=O)C(CCCCN)NC(=O)C4CCCN4C(=O)C(CCCN=C(N)N)N Ambient -20°C "Yang L, Liu C, Dang H, et al. Substance P attenuates hyperoxia induced lung injury in neonatal rats. Mol Med Rep. 2014 Feb;9(2):595-9. PMID: 24247295.

 

Campolongo P, Ratano P, Ciotti MT, et al. Systemic administration of substance P recovers beta amyloid-induced cognitive deficits in rat: involvement of Kv potassium channels. PLoS One. 2013 Nov 12;8(11):e78036. PMID: 24265678.

 

Yang JH, Guo Z, Zhang T, et al. Restoration of endogenous substance P is associated with inhibition of apoptosis of retinal cells in diabetic rats. Regul Pept. 2013 Nov 10;187:12-6. PMID: 24045094.

 

Ma W, Zhang X, Shi S, et al. Neuropeptides stimulate human osteoblast activity and promote gap junctional intercellular communication. Neuropeptides. 2013 Jun;47(3):179-86. PMID: 23726661.

 

Brancati SB, Zádori ZS, Németh J, et al. Substance P induces gastric mucosal protection at supraspinal level via increasing the level of endomorphin-2 in rats. Brain Res Bull. 2013 Feb;91:38-45. PMID: 23328537.

 

Ping F, Shang J, Zhou J, et al. Activation of neurokinin-1 receptor by substance P inhibits melanogenesis in B16-F10 melanoma cells. Int J Biochem Cell Biol. 2012 Dec;44(12):2342-8. PMID: 23041339.

" Not dangerous goods.

LKT M1613 Medroxyprogesterone 17-Acetate 5 g 331.9 Synthetic steroid used in HRT; PR, AR, glucocorticoid agonist, 3α-hydroxysteroid dehydrogenase inhibitor. 17-α-Acetoxy-6α-methylprogesterone MAP; Clinovir; Depo-Provera; Farlutal; Nidaxin; Oragest; Prodasone; Provera; Veramix 71-58-9 ≥98% 386.52 C24H34O4 CC1CC2C(CCC3(C2CCC3(C(=O)C)OC(=O)C)C)C4(C1=CC(=O)CC4)C Ambient -20°C Soluble in chloroform or acetone. "Schindler AE, Campagnoli C, Druckmann R, et al. Classification and pharmacology of progestins. Maturitas. 2008 Sep-Oct;61(1-2):171-80. PMID: 19434889.

 

Meyer L, Venard C, Schaeffer V, et al. The biological activity of 3alpha-hydroxysteroid oxido-reductase in the spinal cord regulates thermal and mechanical pain thresholds after sciatic nerve injury. Neurobiol Dis. 2008 Apr;30(1):30-41. PMID: 18291663.

 

Poulin R, Baker D, Poirier D, et al. Androgen and glucocorticoid receptor-mediated inhibition of cell proliferation by medroxyprogesterone acetate in ZR-75-1 human breast cancer cells. Breast Cancer Res Treat. 1989 Mar;13(2):161-72. PMID: 2525057.

" Carc., Repr. Not dangerous goods.

LKT S7970 Strontium Ranelate 1 g 83.7 Bone deterioration inhibitor, potential CaR agonist. 135459-87-9 ≥98% 513.49 C12H6N2O8S Sr2 C(C1=C(SC(=C1C#N)N(CC(=O)[O-])CC(=O)[O-])C(=O)[O-])C(=O)[O-].[Sr+2].[Sr+2] Ambient Ambient "Cattani-Lorente M, Rizzoli R, Ammann P. In vitro bone exposure to strontium improves bone material level properties. Acta Biomater. 2013 Jun;9(6):7005-13. PMID: 23454213.

 

Rodríguez J, Escudero ND, Mandalunis PM. Effect of strontium ranelate on bone remodeling. Acta Odontol Latinoam. 2012;25(2):208-13. PMID: 23230643.

 

Yamaguchi M, Weitzmann MN. The intact strontium ranelate complex stimulates osteoblastogenesis and suppresses osteoclastogenesis by antagonizing NF-κB activation. Mol Cell Biochem. 2012 Jan;359(1-2):399-407. PMID: 21874315.

 

Takaoka S, Yamaguchi T, Yano S, et al. The Calcium-sensing Receptor (CaR) is involved in strontium ranelate-induced osteoblast differentiation and mineralization. Horm Metab Res. 2010 Aug;42(9):627-31. PMID: 20560105.

" Not dangerous goods.

LKT S7970 Strontium Ranelate 5 g 335 Bone deterioration inhibitor, potential CaR agonist. 135459-87-9 ≥98% 513.49 C12H6N2O8S Sr2 C(C1=C(SC(=C1C#N)N(CC(=O)[O-])CC(=O)[O-])C(=O)[O-])C(=O)[O-].[Sr+2].[Sr+2] Ambient Ambient "Cattani-Lorente M, Rizzoli R, Ammann P. In vitro bone exposure to strontium improves bone material level properties. Acta Biomater. 2013 Jun;9(6):7005-13. PMID: 23454213.

 

Rodríguez J, Escudero ND, Mandalunis PM. Effect of strontium ranelate on bone remodeling. Acta Odontol Latinoam. 2012;25(2):208-13. PMID: 23230643.

 

Yamaguchi M, Weitzmann MN. The intact strontium ranelate complex stimulates osteoblastogenesis and suppresses osteoclastogenesis by antagonizing NF-κB activation. Mol Cell Biochem. 2012 Jan;359(1-2):399-407. PMID: 21874315.

 

Takaoka S, Yamaguchi T, Yano S, et al. The Calcium-sensing Receptor (CaR) is involved in strontium ranelate-induced osteoblast differentiation and mineralization. Horm Metab Res. 2010 Aug;42(9):627-31. PMID: 20560105.

" Not dangerous goods.

LKT M1622 Mefenamic Acid 10 g 27.2 NSAID; GABA-A potentiator, COX-1/2 inhibitor. 2-[(2,3-Dimethylphenyl)amino]benzoic acid Bonabol; Coslan; Lysalgo; Mefenacid; Ponstel; Tanston 61-68-7 ≥98% 241.29 C15H15NO2 CC1=C(C(=CC=C1)NC2=CC=CC=C2C(=O)O)C Ambient Ambient Insoluble in water. Sparingly soluble in ether and chloroform. Soluble in alkali hydroxide solutions. "Khansari PS, Halliwell RF. Evidence for neuroprotection by the fenamate NSAID, mefenamic acid. Neurochem Int. 2009 Dec;55(7):683-8. PMID: 19563851.

 

Weiss H, Amberger A, Widschwendter M, et al. Inhibition of store-operated calcium entry contributes to the anti-proliferative effect of non-steroidal anti-inflammatory drugs in human colon cancer cells. Int J Cancer. 2001 Jun 15;92(6):877-82. PMID: 11351310.

 

Halliwell RF, Thomas P, Patten D, et al. Subunit-selective modulation of GABAA receptors by the non-steroidal anti-inflammatory agent, mefenamic acid. Eur J Neurosci. 1999 Aug;11(8):2897-905. PMID: 10457186.

" Xn Not dangerous goods.

LKT M1622 Mefenamic Acid 50 g 47.6 NSAID; GABA-A potentiator, COX-1/2 inhibitor. 2-[(2,3-Dimethylphenyl)amino]benzoic acid Bonabol; Coslan; Lysalgo; Mefenacid; Ponstel; Tanston 61-68-7 ≥98% 241.29 C15H15NO2 CC1=C(C(=CC=C1)NC2=CC=CC=C2C(=O)O)C Ambient Ambient Insoluble in water. Sparingly soluble in ether and chloroform. Soluble in alkali hydroxide solutions. "Khansari PS, Halliwell RF. Evidence for neuroprotection by the fenamate NSAID, mefenamic acid. Neurochem Int. 2009 Dec;55(7):683-8. PMID: 19563851.

 

Weiss H, Amberger A, Widschwendter M, et al. Inhibition of store-operated calcium entry contributes to the anti-proliferative effect of non-steroidal anti-inflammatory drugs in human colon cancer cells. Int J Cancer. 2001 Jun 15;92(6):877-82. PMID: 11351310.

 

Halliwell RF, Thomas P, Patten D, et al. Subunit-selective modulation of GABAA receptors by the non-steroidal anti-inflammatory agent, mefenamic acid. Eur J Neurosci. 1999 Aug;11(8):2897-905. PMID: 10457186.

" Xn Not dangerous goods.

LKT M1622 Mefenamic Acid 100 g 67.9 NSAID; GABA-A potentiator, COX-1/2 inhibitor. 2-[(2,3-Dimethylphenyl)amino]benzoic acid Bonabol; Coslan; Lysalgo; Mefenacid; Ponstel; Tanston 61-68-7 ≥98% 241.29 C15H15NO2 CC1=C(C(=CC=C1)NC2=CC=CC=C2C(=O)O)C Ambient Ambient Insoluble in water. Sparingly soluble in ether and chloroform. Soluble in alkali hydroxide solutions. "Khansari PS, Halliwell RF. Evidence for neuroprotection by the fenamate NSAID, mefenamic acid. Neurochem Int. 2009 Dec;55(7):683-8. PMID: 19563851.

 

Weiss H, Amberger A, Widschwendter M, et al. Inhibition of store-operated calcium entry contributes to the anti-proliferative effect of non-steroidal anti-inflammatory drugs in human colon cancer cells. Int J Cancer. 2001 Jun 15;92(6):877-82. PMID: 11351310.

 

Halliwell RF, Thomas P, Patten D, et al. Subunit-selective modulation of GABAA receptors by the non-steroidal anti-inflammatory agent, mefenamic acid. Eur J Neurosci. 1999 Aug;11(8):2897-905. PMID: 10457186.

" Xn Not dangerous goods.

LKT M1626 Megestrol Acetate 250 mg 47.6 Synthetic progestogen, orexigenic. 17-Hydroxy-6-methylpregna-4,6-diene-3,20-dione acetate Maygace; Megace; Megestil; Nia; Niagestin; Ovaban 595-33-5 ≥98% 384.51 C24H32O4 CC1=CC2C(CCC3(C2CCC3(C(=O)C)OC(=O)C)C)C4(C1=CC(=O)CC4)C Ambient Ambient Insoluble in water. "Yeh SS, Lovitt S, Schuster MW. Usage of megestrol acetate in the treatment of anorexia-cachexia syndrome in the elderly. J Nutr Health Aging. 2009 May;13(5):448-54. PMID: 19390752.

 

Femia RA, Goyette RE. The science of megestrol acetate delivery: potential to improve outcomes in cachexia. BioDrugs. 2005;19(3):179-87. PMID: 15984902.

 

Zhang K, Chow PK. The effect of megestrol acetate on growth of HepG2 cells in vitro and in vivo. Clin Cancer Res. 2004 Aug 1;10(15):5226-32. PMID: 15297426.

" Xn Not dangerous goods.

LKT M1626 Megestrol Acetate 1 g 115.5 Synthetic progestogen, orexigenic. 17-Hydroxy-6-methylpregna-4,6-diene-3,20-dione acetate Maygace; Megace; Megestil; Nia; Niagestin; Ovaban 595-33-5 ≥98% 384.51 C24H32O4 CC1=CC2C(CCC3(C2CCC3(C(=O)C)OC(=O)C)C)C4(C1=CC(=O)CC4)C Ambient Ambient Insoluble in water. "Yeh SS, Lovitt S, Schuster MW. Usage of megestrol acetate in the treatment of anorexia-cachexia syndrome in the elderly. J Nutr Health Aging. 2009 May;13(5):448-54. PMID: 19390752.

 

Femia RA, Goyette RE. The science of megestrol acetate delivery: potential to improve outcomes in cachexia. BioDrugs. 2005;19(3):179-87. PMID: 15984902.

 

Zhang K, Chow PK. The effect of megestrol acetate on growth of HepG2 cells in vitro and in vivo. Clin Cancer Res. 2004 Aug 1;10(15):5226-32. PMID: 15297426.

" Xn Not dangerous goods.

LKT M1626 Megestrol Acetate 5 g 319.4 Synthetic progestogen, orexigenic. 17-Hydroxy-6-methylpregna-4,6-diene-3,20-dione acetate Maygace; Megace; Megestil; Nia; Niagestin; Ovaban 595-33-5 ≥98% 384.51 C24H32O4 CC1=CC2C(CCC3(C2CCC3(C(=O)C)OC(=O)C)C)C4(C1=CC(=O)CC4)C Ambient Ambient Insoluble in water. "Yeh SS, Lovitt S, Schuster MW. Usage of megestrol acetate in the treatment of anorexia-cachexia syndrome in the elderly. J Nutr Health Aging. 2009 May;13(5):448-54. PMID: 19390752.

 

Femia RA, Goyette RE. The science of megestrol acetate delivery: potential to improve outcomes in cachexia. BioDrugs. 2005;19(3):179-87. PMID: 15984902.

 

Zhang K, Chow PK. The effect of megestrol acetate on growth of HepG2 cells in vitro and in vivo. Clin Cancer Res. 2004 Aug 1;10(15):5226-32. PMID: 15297426.

" Xn Not dangerous goods.

LKT S7911 Suc-SDPF-pNA 1 mg 120 Peptide. ≥98% 684.6 C31H36N6O12 Ambient -20°C

LKT M1644 Meloxicam 100 mg 97.2 NSAID; COX-2 inhibitor. 4-hydroxy-2-methyl-N-(5-methyl-2-thiazolyl)-2H-1,2-benzothiazine-3-carboxamide-1, 1-dioxide Metacam; Mobec 71125-38-7 ≥98% 351.41 C14H13N3O4S2 CC1=CN=C(S1)NC(=O)C2=C(C3=CC=CC=C3S(=O)(=O)N2C)O Ambient Ambient Insol in water.  Sol in DMF and DMSO. "Tasaki Y, Yamamoto J, Omura T, et al. Meloxicam ameliorates motor dysfunction and dopaminergic neurodegeneration by maintaining Akt-signaling in a mouse Parkinson's disease model. Neurosci Lett. 2012 Jul 11;521(1):15-9. PMID: 22617635.

 

Edfawy M, Hassan MH, Mansour A, et al. Meloxicam modulates oxidative stress status, inhibits prostaglandin E2, and abrogates apoptosis in carbon tetrachloride-induced rat hepatic injury. Int J Toxicol. 2012 Jun;31(3):276-86. PMID: 22556387.

 

Noble S, Balfour JA. Meloxicam. Drugs. 1996 Mar;51(3):424-32. PMID: 8882380.

 

Malreddy PR, Coetzee JF, Kukanich B, Gehring R. Pharmacokinetics and milk secretion of gabapentin and meloxicam co-administered orally in Holstein-Friesian cows. J Vet Pharmacol Ther. 2013 Feb;36(1):14-20. PMID: 22372845.

" Xn "UN number: 2811     Class:  6.1     Packing group:  III

Proper shipping name:  Toxic solids, organic, n.o.s. (Meloxicam)

Poison inhalation hazard:  No"

LKT M1644 Meloxicam 500 mg 247.2 NSAID; COX-2 inhibitor. 4-hydroxy-2-methyl-N-(5-methyl-2-thiazolyl)-2H-1,2-benzothiazine-3-carboxamide-1, 1-dioxide Metacam; Mobec 71125-38-7 ≥98% 351.41 C14H13N3O4S2 CC1=CN=C(S1)NC(=O)C2=C(C3=CC=CC=C3S(=O)(=O)N2C)O Ambient Ambient Insol in water.  Sol in DMF and DMSO. "Tasaki Y, Yamamoto J, Omura T, et al. Meloxicam ameliorates motor dysfunction and dopaminergic neurodegeneration by maintaining Akt-signaling in a mouse Parkinson's disease model. Neurosci Lett. 2012 Jul 11;521(1):15-9. PMID: 22617635.

 

Edfawy M, Hassan MH, Mansour A, et al. Meloxicam modulates oxidative stress status, inhibits prostaglandin E2, and abrogates apoptosis in carbon tetrachloride-induced rat hepatic injury. Int J Toxicol. 2012 Jun;31(3):276-86. PMID: 22556387.

 

Noble S, Balfour JA. Meloxicam. Drugs. 1996 Mar;51(3):424-32. PMID: 8882380.

 

Malreddy PR, Coetzee JF, Kukanich B, Gehring R. Pharmacokinetics and milk secretion of gabapentin and meloxicam co-administered orally in Holstein-Friesian cows. J Vet Pharmacol Ther. 2013 Feb;36(1):14-20. PMID: 22372845.

" Xn "UN number: 2811     Class:  6.1     Packing group:  III

Proper shipping name:  Toxic solids, organic, n.o.s. (Meloxicam)

Poison inhalation hazard:  No"

LKT S7911 Suc-SDPF-pNA 10 mg 480 Peptide. ≥98% 684.6 C31H36N6O12 Ambient -20°C

LKT M1644 Meloxicam 1 g 336.4 NSAID; COX-2 inhibitor. 4-hydroxy-2-methyl-N-(5-methyl-2-thiazolyl)-2H-1,2-benzothiazine-3-carboxamide-1, 1-dioxide Metacam; Mobec 71125-38-7 ≥98% 351.41 C14H13N3O4S2 CC1=CN=C(S1)NC(=O)C2=C(C3=CC=CC=C3S(=O)(=O)N2C)O Ambient Ambient Insol in water.  Sol in DMF and DMSO. "Tasaki Y, Yamamoto J, Omura T, et al. Meloxicam ameliorates motor dysfunction and dopaminergic neurodegeneration by maintaining Akt-signaling in a mouse Parkinson's disease model. Neurosci Lett. 2012 Jul 11;521(1):15-9. PMID: 22617635.

 

Edfawy M, Hassan MH, Mansour A, et al. Meloxicam modulates oxidative stress status, inhibits prostaglandin E2, and abrogates apoptosis in carbon tetrachloride-induced rat hepatic injury. Int J Toxicol. 2012 Jun;31(3):276-86. PMID: 22556387.

 

Noble S, Balfour JA. Meloxicam. Drugs. 1996 Mar;51(3):424-32. PMID: 8882380.

 

Malreddy PR, Coetzee JF, Kukanich B, Gehring R. Pharmacokinetics and milk secretion of gabapentin and meloxicam co-administered orally in Holstein-Friesian cows. J Vet Pharmacol Ther. 2013 Feb;36(1):14-20. PMID: 22372845.

" Xn "UN number: 2811     Class:  6.1     Packing group:  III

Proper shipping name:  Toxic solids, organic, n.o.s. (Meloxicam)

Poison inhalation hazard:  No"

LKT S7910 Suc-RGPF-pNA 1 mg 120 Peptide. ≥98% 695.7 C32H41N9O9 Ambient -20°C

LKT S7910 Suc-RGPF-pNA 10 mg 480 Peptide. ≥98% 695.7 C32H41N9O9 Ambient -20°C

LKT S7909 Suc-LEPF-pNA 1 mg 120 Peptide. ≥98% 724.7 C35H44N6O11 Ambient -20°C

LKT S7909 Suc-LEPF-pNA 10 mg 480 Peptide. ≥98% 724.7 C35H44N6O11 Ambient -20°C

LKT S7908 Suc-APA-pNA 100 mg 114 Elastase substrate. ≥95% 477.5 C21H27N5O8 Ambient -20°C Oshima G, Akashi K, Yamada M. pH dependence of salt activation of human leukocyte elastase. Arch Biochem Biophys. 1984 Aug 15;233(1):212-8. PMID: 6565481.

LKT S7908 Suc-APA-pNA 1 g 705.1 Elastase substrate. ≥95% 477.5 C21H27N5O8 Ambient -20°C Oshima G, Akashi K, Yamada M. pH dependence of salt activation of human leukocyte elastase. Arch Biochem Biophys. 1984 Aug 15;233(1):212-8. PMID: 6565481.

LKT M1646 Melanin Concentrating Hormone, human/mouse/rat 0.5 mg 209.8 Endogenous peptide hormon involved in energy homeostasis, circadian rhythms, feeding behavior; MCHR agonist. MCH ≥98% 2386.8 C105H160N30O26S4 Ambient -20°C "Palomba M, Seke Etet PF, Veronesi C. Effect of inflammatory challenge on hypothalamic neurons expressing orexinergic and melanin-concentrating hormone. Neurosci Lett. 2014 Jun 6;570:47-52. PMID: 24708924.

 

Ziogas DC, Karagiannis AK, Geiger BM, et al. Inflammation-induced functional connectivity of melanin-concentrating hormone and IL-10. Peptides. 2014 May;55:58-64. PMID: 24556508.

 

Verret L, Goutagny R, Fort P, et al. A role of melanin-concentrating hormone producing neurons in the central regulation of paradoxical sleep. BMC Neurosci. 2003 Sep 9;4:19. PMID: 12964948.

" Not dangerous goods.

LKT M1646 Melanin Concentrating Hormone, human/mouse/rat 1 mg 356.9 Endogenous peptide hormon involved in energy homeostasis, circadian rhythms, feeding behavior; MCHR agonist. MCH ≥98% 2386.8 C105H160N30O26S4 Ambient -20°C "Palomba M, Seke Etet PF, Veronesi C. Effect of inflammatory challenge on hypothalamic neurons expressing orexinergic and melanin-concentrating hormone. Neurosci Lett. 2014 Jun 6;570:47-52. PMID: 24708924.

 

Ziogas DC, Karagiannis AK, Geiger BM, et al. Inflammation-induced functional connectivity of melanin-concentrating hormone and IL-10. Peptides. 2014 May;55:58-64. PMID: 24556508.

 

Verret L, Goutagny R, Fort P, et al. A role of melanin-concentrating hormone producing neurons in the central regulation of paradoxical sleep. BMC Neurosci. 2003 Sep 9;4:19. PMID: 12964948.

" Not dangerous goods.

LKT M1646 Melanin Concentrating Hormone, human/mouse/rat 2.5 mg 630.1 Endogenous peptide hormon involved in energy homeostasis, circadian rhythms, feeding behavior; MCHR agonist. MCH ≥98% 2386.8 C105H160N30O26S4 Ambient -20°C "Palomba M, Seke Etet PF, Veronesi C. Effect of inflammatory challenge on hypothalamic neurons expressing orexinergic and melanin-concentrating hormone. Neurosci Lett. 2014 Jun 6;570:47-52. PMID: 24708924.

 

Ziogas DC, Karagiannis AK, Geiger BM, et al. Inflammation-induced functional connectivity of melanin-concentrating hormone and IL-10. Peptides. 2014 May;55:58-64. PMID: 24556508.

 

Verret L, Goutagny R, Fort P, et al. A role of melanin-concentrating hormone producing neurons in the central regulation of paradoxical sleep. BMC Neurosci. 2003 Sep 9;4:19. PMID: 12964948.

" Not dangerous goods.

LKT S7872 Stresscopin-Related Peptide, human 0.5 mg 300.1 Peptide, urocortin II analog; CRFR2 agonist. SRP 348626-74-4 ≥95% 4687.56 C205H358N68O57 Ambient -20°C "Jin R, Li MZ, Bing YH, et al. Intracerebroventricular injection of stresscopin-related peptide enhances cardiovascular function in conscious rats. Regul Pept. 2013 Sep 10;186:7-11. PMID: 23850799.

 

Grossini E, Caimmi PP, Molinari C, et al. Modulation of calcium movements by urocortin II in endothelial cells. Cell Physiol Biochem. 2010;25(2-3):221-32. PMID: 20110683.

 

Grossini E, Molinari C, Mary DA, et al. The effect of urocortin II administration on the coronary circulation and cardiac function in the anaesthetized pig is nitric-oxide-dependent. Eur J Pharmacol. 2008 Jan 14;578(2-3):242-8. PMID: 17936748.

 

Takahashi K, Totsune K, Murakami O, et al. Urocortins as cardiovascular peptides. Peptides. 2004 Oct;25(10):1723-31. PMID: 15476939.

 

Suda T, Kageyama K, Sakihara S, et al. Physiological roles of urocortins, human homologues of fish urotensin I, and their receptors. Peptides. 2004 Oct;25(10):1689-701. PMID: 15476936.

" Not dangerous goods.

LKT S7872 Stresscopin-Related Peptide, human 1 mg 510 Peptide, urocortin II analog; CRFR2 agonist. SRP 348626-74-4 ≥95% 4687.56 C205H358N68O57 Ambient -20°C "Jin R, Li MZ, Bing YH, et al. Intracerebroventricular injection of stresscopin-related peptide enhances cardiovascular function in conscious rats. Regul Pept. 2013 Sep 10;186:7-11. PMID: 23850799.

 

Grossini E, Caimmi PP, Molinari C, et al. Modulation of calcium movements by urocortin II in endothelial cells. Cell Physiol Biochem. 2010;25(2-3):221-32. PMID: 20110683.

 

Grossini E, Molinari C, Mary DA, et al. The effect of urocortin II administration on the coronary circulation and cardiac function in the anaesthetized pig is nitric-oxide-dependent. Eur J Pharmacol. 2008 Jan 14;578(2-3):242-8. PMID: 17936748.

 

Takahashi K, Totsune K, Murakami O, et al. Urocortins as cardiovascular peptides. Peptides. 2004 Oct;25(10):1723-31. PMID: 15476939.

 

Suda T, Kageyama K, Sakihara S, et al. Physiological roles of urocortins, human homologues of fish urotensin I, and their receptors. Peptides. 2004 Oct;25(10):1689-701. PMID: 15476936.

" Not dangerous goods.

LKT S7872 Stresscopin-Related Peptide, human 2.5 mg 900.1 Peptide, urocortin II analog; CRFR2 agonist. SRP 348626-74-4 ≥95% 4687.56 C205H358N68O57 Ambient -20°C "Jin R, Li MZ, Bing YH, et al. Intracerebroventricular injection of stresscopin-related peptide enhances cardiovascular function in conscious rats. Regul Pept. 2013 Sep 10;186:7-11. PMID: 23850799.

 

Grossini E, Caimmi PP, Molinari C, et al. Modulation of calcium movements by urocortin II in endothelial cells. Cell Physiol Biochem. 2010;25(2-3):221-32. PMID: 20110683.

 

Grossini E, Molinari C, Mary DA, et al. The effect of urocortin II administration on the coronary circulation and cardiac function in the anaesthetized pig is nitric-oxide-dependent. Eur J Pharmacol. 2008 Jan 14;578(2-3):242-8. PMID: 17936748.

 

Takahashi K, Totsune K, Murakami O, et al. Urocortins as cardiovascular peptides. Peptides. 2004 Oct;25(10):1723-31. PMID: 15476939.

 

Suda T, Kageyama K, Sakihara S, et al. Physiological roles of urocortins, human homologues of fish urotensin I, and their receptors. Peptides. 2004 Oct;25(10):1689-701. PMID: 15476936.

" Not dangerous goods.

LKT M1647 Melanin Concentrating Hormone, salmon 0.5 mg 209.8 Endogenous peptide hormone involved in energy homeostasis, circadian rhythms, feeding behavior; MCHR agonist. MCH, salmon ≥98% 2097.9 C89H137N27O24S4 Ambient -20°C "Palomba M, Seke Etet PF, Veronesi C. Effect of inflammatory challenge on hypothalamic neurons expressing orexinergic and melanin-concentrating hormone. Neurosci Lett. 2014 Jun 6;570:47-52. PMID: 24708924.

 

Ziogas DC, Karagiannis AK, Geiger BM, et al. Inflammation-induced functional connectivity of melanin-concentrating hormone and IL-10. Peptides. 2014 May;55:58-64. PMID: 24556508.

 

Verret L, Goutagny R, Fort P, et al. A role of melanin-concentrating hormone producing neurons in the central regulation of paradoxical sleep. BMC Neurosci. 2003 Sep 9;4:19. PMID: 12964948.

" Not dangerous goods.

LKT M1647 Melanin Concentrating Hormone, salmon 1 mg 356.9 Endogenous peptide hormone involved in energy homeostasis, circadian rhythms, feeding behavior; MCHR agonist. MCH, salmon ≥98% 2097.9 C89H137N27O24S4 Ambient -20°C "Palomba M, Seke Etet PF, Veronesi C. Effect of inflammatory challenge on hypothalamic neurons expressing orexinergic and melanin-concentrating hormone. Neurosci Lett. 2014 Jun 6;570:47-52. PMID: 24708924.

 

Ziogas DC, Karagiannis AK, Geiger BM, et al. Inflammation-induced functional connectivity of melanin-concentrating hormone and IL-10. Peptides. 2014 May;55:58-64. PMID: 24556508.

 

Verret L, Goutagny R, Fort P, et al. A role of melanin-concentrating hormone producing neurons in the central regulation of paradoxical sleep. BMC Neurosci. 2003 Sep 9;4:19. PMID: 12964948.

" Not dangerous goods.

LKT M1647 Melanin Concentrating Hormone, salmon 2.5 mg 630.1 Endogenous peptide hormone involved in energy homeostasis, circadian rhythms, feeding behavior; MCHR agonist. MCH, salmon ≥98% 2097.9 C89H137N27O24S4 Ambient -20°C "Palomba M, Seke Etet PF, Veronesi C. Effect of inflammatory challenge on hypothalamic neurons expressing orexinergic and melanin-concentrating hormone. Neurosci Lett. 2014 Jun 6;570:47-52. PMID: 24708924.

 

Ziogas DC, Karagiannis AK, Geiger BM, et al. Inflammation-induced functional connectivity of melanin-concentrating hormone and IL-10. Peptides. 2014 May;55:58-64. PMID: 24556508.

 

Verret L, Goutagny R, Fort P, et al. A role of melanin-concentrating hormone producing neurons in the central regulation of paradoxical sleep. BMC Neurosci. 2003 Sep 9;4:19. PMID: 12964948.

" Not dangerous goods.

LKT M1648 Melanostatin, frog 2.5 mg 900.1 Neuropeptide; D2 modulator. MIF-1 ≥95% 4243.76 C189H285N53O57S1 Ambient -20°C "Pan W, Kastin AJ. From MIF-1 to endomorphin: the Tyr-MIF-1 family of peptides. Peptides. 2007 Dec;28(12):2411-34. PMID: 17988762.

 

Mishra RK, Makman MH, Costain WJ, et al. Modulation of agonist stimulated adenylyl cyclase and GTPase activity by L-pro-L-leu-glycinamide and its peptidomimetic analogue in rat striatal membranes. Neurosci Lett. 1999 Jul 2;269(1):21-4. PMID: 10821635.

 

Kostowski W, Danysz W, Dyr W, et al. MIF-1 potentiates the action of tricyclic antidepressants in an animal model of depression. Peptides. 1991 Sep-Oct;12(5):915-8. PMID: 1686934.

"

LKT M1648 Melanostatin, frog 1 mg 510 Neuropeptide; D2 modulator. MIF-1 ≥95% 4243.76 C189H285N53O57S1 Ambient -20°C "Pan W, Kastin AJ. From MIF-1 to endomorphin: the Tyr-MIF-1 family of peptides. Peptides. 2007 Dec;28(12):2411-34. PMID: 17988762.

 

Mishra RK, Makman MH, Costain WJ, et al. Modulation of agonist stimulated adenylyl cyclase and GTPase activity by L-pro-L-leu-glycinamide and its peptidomimetic analogue in rat striatal membranes. Neurosci Lett. 1999 Jul 2;269(1):21-4. PMID: 10821635.

 

Kostowski W, Danysz W, Dyr W, et al. MIF-1 potentiates the action of tricyclic antidepressants in an animal model of depression. Peptides. 1991 Sep-Oct;12(5):915-8. PMID: 1686934.

"

LKT M1648 Melanostatin, frog 0.5 mg 300.1 Neuropeptide; D2 modulator. MIF-1 ≥95% 4243.76 C189H285N53O57S1 Ambient -20°C "Pan W, Kastin AJ. From MIF-1 to endomorphin: the Tyr-MIF-1 family of peptides. Peptides. 2007 Dec;28(12):2411-34. PMID: 17988762.

 

Mishra RK, Makman MH, Costain WJ, et al. Modulation of agonist stimulated adenylyl cyclase and GTPase activity by L-pro-L-leu-glycinamide and its peptidomimetic analogue in rat striatal membranes. Neurosci Lett. 1999 Jul 2;269(1):21-4. PMID: 10821635.

 

Kostowski W, Danysz W, Dyr W, et al. MIF-1 potentiates the action of tricyclic antidepressants in an animal model of depression. Peptides. 1991 Sep-Oct;12(5):915-8. PMID: 1686934.

"

LKT S7871 Stresscopin, human 0.5 mg 276.2 Peptide, urocortin III analog; CRFR2 agonist. 352020-03-2 ≥95% 4367.24 C195H326N56O53S2 Ambient -20°C "Jin R, Li MZ, Bing YH, et al. Intracerebroventricular injection of stresscopin-related peptide enhances cardiovascular function in conscious rats. Regul Pept. 2013 Sep 10;186:7-11. PMID: 23850799.

 

Bagosi Z, Csabafi K, Palotai M, et al. The interaction of Urocortin II and Urocortin III with amygdalar and hypothalamic cotricotropin-releasing factor (CRF)--reflections on the regulation of the hypothalamic-pituitary-adrenal (HPA) axis. Neuropeptides. 2013 Oct;47(5):333-8. PMID: 23932308.

 

Takahashi K, Totsune K, Murakami O, et al. Urocortins as cardiovascular peptides. Peptides. 2004 Oct;25(10):1723-31. PMID: 15476939.

 

Suda T, Kageyama K, Sakihara S, et al. Physiological roles of urocortins, human homologues of fish urotensin I, and their receptors. Peptides. 2004 Oct;25(10):1689-701. PMID: 15476936.

" Not dangerous goods.

LKT S7871 Stresscopin, human 1 mg 468.2 Peptide, urocortin III analog; CRFR2 agonist. 352020-03-2 ≥95% 4367.24 C195H326N56O53S2 Ambient -20°C "Jin R, Li MZ, Bing YH, et al. Intracerebroventricular injection of stresscopin-related peptide enhances cardiovascular function in conscious rats. Regul Pept. 2013 Sep 10;186:7-11. PMID: 23850799.

 

Bagosi Z, Csabafi K, Palotai M, et al. The interaction of Urocortin II and Urocortin III with amygdalar and hypothalamic cotricotropin-releasing factor (CRF)--reflections on the regulation of the hypothalamic-pituitary-adrenal (HPA) axis. Neuropeptides. 2013 Oct;47(5):333-8. PMID: 23932308.

 

Takahashi K, Totsune K, Murakami O, et al. Urocortins as cardiovascular peptides. Peptides. 2004 Oct;25(10):1723-31. PMID: 15476939.

 

Suda T, Kageyama K, Sakihara S, et al. Physiological roles of urocortins, human homologues of fish urotensin I, and their receptors. Peptides. 2004 Oct;25(10):1689-701. PMID: 15476936.

" Not dangerous goods.

LKT S7871 Stresscopin, human 2.5 mg 828.1 Peptide, urocortin III analog; CRFR2 agonist. 352020-03-2 ≥95% 4367.24 C195H326N56O53S2 Ambient -20°C "Jin R, Li MZ, Bing YH, et al. Intracerebroventricular injection of stresscopin-related peptide enhances cardiovascular function in conscious rats. Regul Pept. 2013 Sep 10;186:7-11. PMID: 23850799.

 

Bagosi Z, Csabafi K, Palotai M, et al. The interaction of Urocortin II and Urocortin III with amygdalar and hypothalamic cotricotropin-releasing factor (CRF)--reflections on the regulation of the hypothalamic-pituitary-adrenal (HPA) axis. Neuropeptides. 2013 Oct;47(5):333-8. PMID: 23932308.

 

Takahashi K, Totsune K, Murakami O, et al. Urocortins as cardiovascular peptides. Peptides. 2004 Oct;25(10):1723-31. PMID: 15476939.

 

Suda T, Kageyama K, Sakihara S, et al. Physiological roles of urocortins, human homologues of fish urotensin I, and their receptors. Peptides. 2004 Oct;25(10):1689-701. PMID: 15476936.

" Not dangerous goods.

LKT M1649 Melanoma-associated Antigen Peptide 1 (27-35), human 1 mg 120 Melanoma-associated antigen. MART-1 (27-35) ≥95% 814 C37H67N9O11 Ambient -20°C "Chodon T, Comin-Anduix B, Chmielowski B, et al. Adoptive Transfer of MART-1 T-Cell Receptor Transgenic Lymphocytes and Dendritic Cell Vaccination in Patients with Metastatic Melanoma. Clin Cancer Res. 2014 May 1;20(9):2457-65. PMID: 24634374.

 

Romano E, Michielin O, Voelter V, et al. MART-1 peptide vaccination plus IMP321 (LAG-3Ig fusion protein) in patients receiving autologous PBMCs after lymphodepletion: results of a Phase I trial. J Transl Med. 2014 Apr 12;12:97. PMID: 24726012.

"

LKT M1649 Melanoma-associated Antigen Peptide 1 (27-35), human 2 mg 204.1 Melanoma-associated antigen. MART-1 (27-35) ≥95% 814 C37H67N9O11 Ambient -20°C "Chodon T, Comin-Anduix B, Chmielowski B, et al. Adoptive Transfer of MART-1 T-Cell Receptor Transgenic Lymphocytes and Dendritic Cell Vaccination in Patients with Metastatic Melanoma. Clin Cancer Res. 2014 May 1;20(9):2457-65. PMID: 24634374.

 

Romano E, Michielin O, Voelter V, et al. MART-1 peptide vaccination plus IMP321 (LAG-3Ig fusion protein) in patients receiving autologous PBMCs after lymphodepletion: results of a Phase I trial. J Transl Med. 2014 Apr 12;12:97. PMID: 24726012.

"

LKT M1649 Melanoma-associated Antigen Peptide 1 (27-35), human 5 mg 359.9 Melanoma-associated antigen. MART-1 (27-35) ≥95% 814 C37H67N9O11 Ambient -20°C "Chodon T, Comin-Anduix B, Chmielowski B, et al. Adoptive Transfer of MART-1 T-Cell Receptor Transgenic Lymphocytes and Dendritic Cell Vaccination in Patients with Metastatic Melanoma. Clin Cancer Res. 2014 May 1;20(9):2457-65. PMID: 24634374.

 

Romano E, Michielin O, Voelter V, et al. MART-1 peptide vaccination plus IMP321 (LAG-3Ig fusion protein) in patients receiving autologous PBMCs after lymphodepletion: results of a Phase I trial. J Transl Med. 2014 Apr 12;12:97. PMID: 24726012.

"

LKT S7870 Streptozocin 50 mg 37.8 Nitrosourea-amino sugar conjugate, DNA cross-linker, used to induce diabetes-like conditions; gluconeogenesis inhibitor 2-Deoxy-2-[[(methylnitrosoamino)carbonyl]amino]-D-glucopyranose Streptozotocin; NSC-85998; U-9889; Zanosar 18883-66-4 ≥98% 265.22 C8H15N3O7 CN(C(=O)NC1C(C(C(OC1O)CO)O)O)N=O Stable at room temperature. Ambient -20°C Soluble in water, ketones and lower alcohols. "Rerup CC. Drugs producing diabetes through damage of the insulin secreting cells. Pharmacol Rev. 1970 Dec;22(4):485-518. PMID: 4921840.

 

Murray-Lyon IM, Eddleston AL, Williams R, et al. Treatment of multiple-hormone-producing malignant islet-cell tumour with streptozotocin. Lancet. 1968 Oct 26;2(7574):895-8. PMID: 4176152.

 

Vavra JJ, Deboer C, Dietz A, et al. Streptozotocin, a new antibacterial antibiotic. Antibiot Annu. 1959-1960;7:230-5. PMID: 13841501.

" T "UN number: 3077     Class:  9     Packing group:  III

Proper shipping name:  Environmentally hazardous substance, solid, n.o.s. (Streptozocin)

Reportable quantity (RQ):  1 lbs / Marine pollutant:  No / Poison inhalation hazard:  No"

LKT S7870 Streptozocin 100 mg 58.9 Nitrosourea-amino sugar conjugate, DNA cross-linker, used to induce diabetes-like conditions; gluconeogenesis inhibitor 2-Deoxy-2-[[(methylnitrosoamino)carbonyl]amino]-D-glucopyranose Streptozotocin; NSC-85998; U-9889; Zanosar 18883-66-4 ≥98% 265.22 C8H15N3O7 CN(C(=O)NC1C(C(C(OC1O)CO)O)O)N=O Stable at room temperature. Ambient -20°C Soluble in water, ketones and lower alcohols. "Rerup CC. Drugs producing diabetes through damage of the insulin secreting cells. Pharmacol Rev. 1970 Dec;22(4):485-518. PMID: 4921840.

 

Murray-Lyon IM, Eddleston AL, Williams R, et al. Treatment of multiple-hormone-producing malignant islet-cell tumour with streptozotocin. Lancet. 1968 Oct 26;2(7574):895-8. PMID: 4176152.

 

Vavra JJ, Deboer C, Dietz A, et al. Streptozotocin, a new antibacterial antibiotic. Antibiot Annu. 1959-1960;7:230-5. PMID: 13841501.

" T "UN number: 3077     Class:  9     Packing group:  III

Proper shipping name:  Environmentally hazardous substance, solid, n.o.s. (Streptozocin)

Reportable quantity (RQ):  1 lbs / Marine pollutant:  No / Poison inhalation hazard:  No"

LKT M1650 Melanotan II 5 mg 180 Synthetis peptide, melanocortin analog; MCR agonist. L-Lysinamide,N-acetyl-L-norleucyl-L-alpha-aspartyl- L-histidyl-D-phenylalanyl-L-arginyl-L-tryptophyl- ,cyclic (2-7)-peptide MT-II 121062-08-6 ≥98% 1024.2 C50H69N15O9 CCCCC(C(=O)NC1CC(=O)NCCCCC(NC(=O)C(NC(=O)C(NC(=O)C(NC(=O)C(NC1=O)CC2=CN=CN2)CC3=CC=CC=C3)CCCN=C(N)N)CC4=CNC5=CC=CC=C54)C(=O)N)NC(=O)C Ambient -20°C "Monge-Roffarello B, Labbé SM, Lenglos C, et al. The medial preoptic nucleus as a site of the thermogenic and metabolic actions of Melanotan II in male rats. Am J Physiol Regul Integr Comp Physiol. 2014 May 7. [Epub ahead of print]. PMID: 24808495.

 

Rinne P, Silvola JM, Hellberg S, et al.  Pharmacological Activation of the Melanocortin System Limits Plaque Inflammation and Ameliorates Vascular Dysfunction in Atherosclerotic Mice. Arterioscler Thromb Vasc Biol. 2014 May 1. [Epub ahead of print]. PMID: 24790139.

 

Hjuler KF, Lorentzen HF. Melanoma associated with the use of melanotan-II. Dermatology. 2014;228(1):34-6. PMID: 24355990.

 

Hadley ME. Discovery that a melanocortin regulates sexual functions in male and female humans. Peptides. 2005 Oct;26(10):1687-9. PMID: 15996790.

" Not dangerous goods.

LKT M1650 Melanotan II 10 mg 306.1 Synthetis peptide, melanocortin analog; MCR agonist. L-Lysinamide,N-acetyl-L-norleucyl-L-alpha-aspartyl- L-histidyl-D-phenylalanyl-L-arginyl-L-tryptophyl- ,cyclic (2-7)-peptide MT-II 121062-08-6 ≥98% 1024.2 C50H69N15O9 CCCCC(C(=O)NC1CC(=O)NCCCCC(NC(=O)C(NC(=O)C(NC(=O)C(NC(=O)C(NC1=O)CC2=CN=CN2)CC3=CC=CC=C3)CCCN=C(N)N)CC4=CNC5=CC=CC=C54)C(=O)N)NC(=O)C Ambient -20°C "Monge-Roffarello B, Labbé SM, Lenglos C, et al. The medial preoptic nucleus as a site of the thermogenic and metabolic actions of Melanotan II in male rats. Am J Physiol Regul Integr Comp Physiol. 2014 May 7. [Epub ahead of print]. PMID: 24808495.

 

Rinne P, Silvola JM, Hellberg S, et al.  Pharmacological Activation of the Melanocortin System Limits Plaque Inflammation and Ameliorates Vascular Dysfunction in Atherosclerotic Mice. Arterioscler Thromb Vasc Biol. 2014 May 1. [Epub ahead of print]. PMID: 24790139.

 

Hjuler KF, Lorentzen HF. Melanoma associated with the use of melanotan-II. Dermatology. 2014;228(1):34-6. PMID: 24355990.

 

Hadley ME. Discovery that a melanocortin regulates sexual functions in male and female humans. Peptides. 2005 Oct;26(10):1687-9. PMID: 15996790.

" Not dangerous goods.

LKT M1650 Melanotan II 25 mg 540 Synthetis peptide, melanocortin analog; MCR agonist. L-Lysinamide,N-acetyl-L-norleucyl-L-alpha-aspartyl- L-histidyl-D-phenylalanyl-L-arginyl-L-tryptophyl- ,cyclic (2-7)-peptide MT-II 121062-08-6 ≥98% 1024.2 C50H69N15O9 CCCCC(C(=O)NC1CC(=O)NCCCCC(NC(=O)C(NC(=O)C(NC(=O)C(NC(=O)C(NC1=O)CC2=CN=CN2)CC3=CC=CC=C3)CCCN=C(N)N)CC4=CNC5=CC=CC=C54)C(=O)N)NC(=O)C Ambient -20°C "Monge-Roffarello B, Labbé SM, Lenglos C, et al. The medial preoptic nucleus as a site of the thermogenic and metabolic actions of Melanotan II in male rats. Am J Physiol Regul Integr Comp Physiol. 2014 May 7. [Epub ahead of print]. PMID: 24808495.

 

Rinne P, Silvola JM, Hellberg S, et al.  Pharmacological Activation of the Melanocortin System Limits Plaque Inflammation and Ameliorates Vascular Dysfunction in Atherosclerotic Mice. Arterioscler Thromb Vasc Biol. 2014 May 1. [Epub ahead of print]. PMID: 24790139.

 

Hjuler KF, Lorentzen HF. Melanoma associated with the use of melanotan-II. Dermatology. 2014;228(1):34-6. PMID: 24355990.

 

Hadley ME. Discovery that a melanocortin regulates sexual functions in male and female humans. Peptides. 2005 Oct;26(10):1687-9. PMID: 15996790.

" Not dangerous goods.

LKT S7870 Streptozocin 500 mg 169.9 Nitrosourea-amino sugar conjugate, DNA cross-linker, used to induce diabetes-like conditions; gluconeogenesis inhibitor 2-Deoxy-2-[[(methylnitrosoamino)carbonyl]amino]-D-glucopyranose Streptozotocin; NSC-85998; U-9889; Zanosar 18883-66-4 ≥98% 265.22 C8H15N3O7 CN(C(=O)NC1C(C(C(OC1O)CO)O)O)N=O Stable at room temperature. Ambient -20°C Soluble in water, ketones and lower alcohols. "Rerup CC. Drugs producing diabetes through damage of the insulin secreting cells. Pharmacol Rev. 1970 Dec;22(4):485-518. PMID: 4921840.

 

Murray-Lyon IM, Eddleston AL, Williams R, et al. Treatment of multiple-hormone-producing malignant islet-cell tumour with streptozotocin. Lancet. 1968 Oct 26;2(7574):895-8. PMID: 4176152.

 

Vavra JJ, Deboer C, Dietz A, et al. Streptozotocin, a new antibacterial antibiotic. Antibiot Annu. 1959-1960;7:230-5. PMID: 13841501.

" T "UN number: 3077     Class:  9     Packing group:  III

Proper shipping name:  Environmentally hazardous substance, solid, n.o.s. (Streptozocin)

Reportable quantity (RQ):  1 lbs / Marine pollutant:  No / Poison inhalation hazard:  No"

LKT M1669 6-Mercaptopurine Monohydrate 5 g 83.5 Thiopurine antimetabolite; PRPP amidotransferase inhibitor. 1,7-Dihydro-6H-pyrine-6-thione Purine-6-thiol; 6MP; Leukerin Mercaleukin; Purinethol: 6-Purinethiol 6112-76-1 ≥98% 170.2 C5H4N4S H2O C1=NC2=C(N1)C(=S)N=CN2.O Ambient Ambient Insoluble in water.  Soluble in Methanol and hot ethanol. "Bradford K, Shih DQ. Optimizing 6-mercaptopurine and azathioprine therapy in the management of inflammatory bowel disease. World J Gastroenterol. 2011 Oct 7;17(37):4166-73. PMID: 22072847.

 

Nielsen OH, Vainer B, Rask-Madsen J. Review article: the treatment of inflammatory bowel disease with 6-mercaptopurine or azathioprine. Aliment Pharmacol Ther. 2001 Nov;15(11):1699-708. PMID: 11683683.

 

Lennard L, Welch JC, Lilleyman JS. Thiopurine drugs in the treatment of childhood leukaemia: the influence of inherited thiopurine methyltransferase activity on drug metabolism and cytotoxicity. Br J Clin Pharmacol. 1997 Nov;44(5):455-61. PMID: 9384462.

" Xn Not dangerous goods.

LKT M1669 6-Mercaptopurine Monohydrate 25 g 283.6 Thiopurine antimetabolite; PRPP amidotransferase inhibitor. 1,7-Dihydro-6H-pyrine-6-thione Purine-6-thiol; 6MP; Leukerin Mercaleukin; Purinethol: 6-Purinethiol 6112-76-1 ≥98% 170.2 C5H4N4S H2O C1=NC2=C(N1)C(=S)N=CN2.O Ambient Ambient Insoluble in water.  Soluble in Methanol and hot ethanol. "Bradford K, Shih DQ. Optimizing 6-mercaptopurine and azathioprine therapy in the management of inflammatory bowel disease. World J Gastroenterol. 2011 Oct 7;17(37):4166-73. PMID: 22072847.

 

Nielsen OH, Vainer B, Rask-Madsen J. Review article: the treatment of inflammatory bowel disease with 6-mercaptopurine or azathioprine. Aliment Pharmacol Ther. 2001 Nov;15(11):1699-708. PMID: 11683683.

 

Lennard L, Welch JC, Lilleyman JS. Thiopurine drugs in the treatment of childhood leukaemia: the influence of inherited thiopurine methyltransferase activity on drug metabolism and cytotoxicity. Br J Clin Pharmacol. 1997 Nov;44(5):455-61. PMID: 9384462.

" Xn Not dangerous goods.

LKT S7769 Streptomycin Sulfate 25 g 26.8 Aminoglycoside; protein translation inhibitor, mammalian mRNA splicing inhibitor. Steptomycin Sesquisulfate; AgriStrep; Vetstrep 3810-74-0 ≥98% 1457.39 (C21H39N7O12)2 3H2SO4 CC1C(C(C(O1)OC2C(C(C(C(C2O)O)N=C(N)N)O)N=C(N)N)OC3C(C(C(C(O3)CO)O)O)NC)(C=O)O.CC1C(C(C(O1)OC2C(C(C(C(C2O)O)N=C(N)N)O)N=C(N)N)OC3C(C(C(C(O3)CO)O)O)NC)(C=O)O.OS(=O)(=O)O.OS(=O)(=O)O.OS(=O)(=O)O Ambient Ambient Soluble in water. "Ruiz P, Rodríguez-Cano F, Zerolo FJ, et al. Streptomycin as second-line chemotherapy for tuberculosis. Rev Esp Quimioter. 2003 Jun;16(2):188-94. PMID: 12973456.

 

Hertweck M, Hiller R, Mueller MW. Inhibition of nuclear pre-mRNA splicing by antibiotics in vitro. Eur J Biochem. 2002 Jan;269(1):175-83. PMID: 11784311.

 

Zhu M, Burman WJ, Jaresko GS, et al. Population pharmacokinetics of intravenous and intramuscular streptomycin in patients with tuberculosis. Pharmacotherapy. 2001 Sep;21(9):1037-45. PMID: 11560193." Not dangerous goods.

LKT S7769 Streptomycin Sulfate 50 g 46.1 Aminoglycoside; protein translation inhibitor, mammalian mRNA splicing inhibitor. Steptomycin Sesquisulfate; AgriStrep; Vetstrep 3810-74-0 ≥98% 1457.39 (C21H39N7O12)2 3H2SO4 CC1C(C(C(O1)OC2C(C(C(C(C2O)O)N=C(N)N)O)N=C(N)N)OC3C(C(C(C(O3)CO)O)O)NC)(C=O)O.CC1C(C(C(O1)OC2C(C(C(C(C2O)O)N=C(N)N)O)N=C(N)N)OC3C(C(C(C(O3)CO)O)O)NC)(C=O)O.OS(=O)(=O)O.OS(=O)(=O)O.OS(=O)(=O)O Ambient Ambient Soluble in water. "Ruiz P, Rodríguez-Cano F, Zerolo FJ, et al. Streptomycin as second-line chemotherapy for tuberculosis. Rev Esp Quimioter. 2003 Jun;16(2):188-94. PMID: 12973456.

 

Hertweck M, Hiller R, Mueller MW. Inhibition of nuclear pre-mRNA splicing by antibiotics in vitro. Eur J Biochem. 2002 Jan;269(1):175-83. PMID: 11784311.

 

Zhu M, Burman WJ, Jaresko GS, et al. Population pharmacokinetics of intravenous and intramuscular streptomycin in patients with tuberculosis. Pharmacotherapy. 2001 Sep;21(9):1037-45. PMID: 11560193." Not dangerous goods.

LKT S7769 Streptomycin Sulfate 100 g 72.8 Aminoglycoside; protein translation inhibitor, mammalian mRNA splicing inhibitor. Steptomycin Sesquisulfate; AgriStrep; Vetstrep 3810-74-0 ≥98% 1457.39 (C21H39N7O12)2 3H2SO4 CC1C(C(C(O1)OC2C(C(C(C(C2O)O)N=C(N)N)O)N=C(N)N)OC3C(C(C(C(O3)CO)O)O)NC)(C=O)O.CC1C(C(C(O1)OC2C(C(C(C(C2O)O)N=C(N)N)O)N=C(N)N)OC3C(C(C(C(O3)CO)O)O)NC)(C=O)O.OS(=O)(=O)O.OS(=O)(=O)O.OS(=O)(=O)O Ambient Ambient Soluble in water. "Ruiz P, Rodríguez-Cano F, Zerolo FJ, et al. Streptomycin as second-line chemotherapy for tuberculosis. Rev Esp Quimioter. 2003 Jun;16(2):188-94. PMID: 12973456.

 

Hertweck M, Hiller R, Mueller MW. Inhibition of nuclear pre-mRNA splicing by antibiotics in vitro. Eur J Biochem. 2002 Jan;269(1):175-83. PMID: 11784311.

 

Zhu M, Burman WJ, Jaresko GS, et al. Population pharmacokinetics of intravenous and intramuscular streptomycin in patients with tuberculosis. Pharmacotherapy. 2001 Sep;21(9):1037-45. PMID: 11560193." Not dangerous goods.

LKT M1676 Methotrexate Hydrate 10 mg 42.2 DHF reductase inhibitor. N-[4-[[(2,4-Diamino-6-pteridinyl)methyl]methyl- amino]benzoyl]-L-glutamic acid L-(+)-Amethopterin Dihydrate; Amethopterin; MTX; Emtexate; Ledertrexate; Rheumatrex 6745-93-3 ≥98% 472.45 C20H22N8O5 CN(CC1=CN=C2C(=N1)C(=NC(=N2)N)N)C3=CC=C(C=C3)C(=O)NC(CCC(=O)O)C(=O)O Ambient -20°C Not soluble in water or ethanol.  Soluble in dilute HCl and in alkaline soln. "Herfarth HH, Long MD, Isaacs KL. Methotrexate: underused and ignored? Dig Dis. 2012;30 Suppl 3:112-8. doi: 10.1159/000342735. PMID: 23295701.

 

Mol F, Mol BW, Ankum WM, et al.  Current evidence on surgery, systemic methotrexate and expectant management in the treatment of tubal ectopic pregnancy: a systematic review and meta-analysis. Hum Reprod Update. 2008 Jul-Aug;14(4):309-19. PMID: 18522946.

 

Wessels JA, Huizinga TW, Guchelaar HJ. Recent insights in the pharmacological actions of methotrexate in the treatment of rheumatoid arthritis. Rheumatology (Oxford). 2008 Mar;47(3):249-55. PMID: 18045808.

" T, Repr., Xi "UN number: 2811     Class: 6.1     Packing Group: III

Proper shipping name: Toxic solid, oxidizing, n.o.s. (Methotrexate hydrate)"

LKT M1676 Methotrexate Hydrate 50 mg 74 DHF reductase inhibitor. N-[4-[[(2,4-Diamino-6-pteridinyl)methyl]methyl- amino]benzoyl]-L-glutamic acid L-(+)-Amethopterin Dihydrate; Amethopterin; MTX; Emtexate; Ledertrexate; Rheumatrex 6745-93-3 ≥98% 472.45 C20H22N8O5 CN(CC1=CN=C2C(=N1)C(=NC(=N2)N)N)C3=CC=C(C=C3)C(=O)NC(CCC(=O)O)C(=O)O Ambient -20°C Not soluble in water or ethanol.  Soluble in dilute HCl and in alkaline soln. "Herfarth HH, Long MD, Isaacs KL. Methotrexate: underused and ignored? Dig Dis. 2012;30 Suppl 3:112-8. doi: 10.1159/000342735. PMID: 23295701.

 

Mol F, Mol BW, Ankum WM, et al.  Current evidence on surgery, systemic methotrexate and expectant management in the treatment of tubal ectopic pregnancy: a systematic review and meta-analysis. Hum Reprod Update. 2008 Jul-Aug;14(4):309-19. PMID: 18522946.

 

Wessels JA, Huizinga TW, Guchelaar HJ. Recent insights in the pharmacological actions of methotrexate in the treatment of rheumatoid arthritis. Rheumatology (Oxford). 2008 Mar;47(3):249-55. PMID: 18045808.

" T, Repr., Xi "UN number: 2811     Class: 6.1     Packing Group: III

Proper shipping name: Toxic solid, oxidizing, n.o.s. (Methotrexate hydrate)"

LKT S7717 Sterigmatocystin 1 mg 58.7 Mycotoxin produced by Aspergillus; carcinogen. 10048-13-2 ≥98% 324.28 C18H12O6 COC1=C2C(=C3C4C=COC4OC3=C1)OC5=C(C2=O)C(=CC=C5)O Ambient 4°C DMSO, Methanol, Ethanol, Acetone. "Zhang D, Cui Y, Shen H, et al. Sterigmatocystin-induced DNA damage triggers G2 arrest via an ATM/p53-related pathway in human gastric epithelium GES-1 cells in vitro. PLoS One. 2013 May 21;8(5):e65044. PMID: 23705030.

 

Xing X, Wang J, Xing LX, et al. Involvement of MAPK and PI3K signaling pathway in sterigmatocystin-induced G2 phase arrest in human gastric epithelium cells. Mol Nutr Food Res. 2011 May;55(5):749-60. PMID: 21287681.

 

Delgado-Virgen F, Guzman-de-Peña D. Mechanism of Sterigmatocystin Biosynthesis Regulation by pH in Aspergillus nidulans. Braz J Microbiol. 2009 Oct;40(4):933-42. PMID: 24031444.

 

Sivakumar V, Thanislass J, Niranjali S, et al. Lipid peroxidation as a possible secondary mechanism of sterigmatocystin toxicity. Hum Exp Toxicol. 2001 Aug;20(8):398-403. PMID: 11727790.

" T, Carc. Cat. 3 "UN number: 3462     Class: 6.1     Packing Group: III

Proper shipping name: Toxins, extracted from living sources, solid, n.o.s. (Sterigmatocystin)"

LKT M1676 Methotrexate Hydrate 100 mg 118.9 DHF reductase inhibitor. N-[4-[[(2,4-Diamino-6-pteridinyl)methyl]methyl- amino]benzoyl]-L-glutamic acid L-(+)-Amethopterin Dihydrate; Amethopterin; MTX; Emtexate; Ledertrexate; Rheumatrex 6745-93-3 ≥98% 472.45 C20H22N8O5 CN(CC1=CN=C2C(=N1)C(=NC(=N2)N)N)C3=CC=C(C=C3)C(=O)NC(CCC(=O)O)C(=O)O Ambient -20°C Not soluble in water or ethanol.  Soluble in dilute HCl and in alkaline soln. "Herfarth HH, Long MD, Isaacs KL. Methotrexate: underused and ignored? Dig Dis. 2012;30 Suppl 3:112-8. doi: 10.1159/000342735. PMID: 23295701.

 

Mol F, Mol BW, Ankum WM, et al.  Current evidence on surgery, systemic methotrexate and expectant management in the treatment of tubal ectopic pregnancy: a systematic review and meta-analysis. Hum Reprod Update. 2008 Jul-Aug;14(4):309-19. PMID: 18522946.

 

Wessels JA, Huizinga TW, Guchelaar HJ. Recent insights in the pharmacological actions of methotrexate in the treatment of rheumatoid arthritis. Rheumatology (Oxford). 2008 Mar;47(3):249-55. PMID: 18045808.

" T, Repr., Xi "UN number: 2811     Class: 6.1     Packing Group: III

Proper shipping name: Toxic solid, oxidizing, n.o.s. (Methotrexate hydrate)"

LKT M1676 Methotrexate Hydrate 500 mg 564.3 DHF reductase inhibitor. N-[4-[[(2,4-Diamino-6-pteridinyl)methyl]methyl- amino]benzoyl]-L-glutamic acid L-(+)-Amethopterin Dihydrate; Amethopterin; MTX; Emtexate; Ledertrexate; Rheumatrex 6745-93-3 ≥98% 472.45 C20H22N8O5 CN(CC1=CN=C2C(=N1)C(=NC(=N2)N)N)C3=CC=C(C=C3)C(=O)NC(CCC(=O)O)C(=O)O Ambient -20°C Not soluble in water or ethanol.  Soluble in dilute HCl and in alkaline soln. "Herfarth HH, Long MD, Isaacs KL. Methotrexate: underused and ignored? Dig Dis. 2012;30 Suppl 3:112-8. doi: 10.1159/000342735. PMID: 23295701.

 

Mol F, Mol BW, Ankum WM, et al.  Current evidence on surgery, systemic methotrexate and expectant management in the treatment of tubal ectopic pregnancy: a systematic review and meta-analysis. Hum Reprod Update. 2008 Jul-Aug;14(4):309-19. PMID: 18522946.

 

Wessels JA, Huizinga TW, Guchelaar HJ. Recent insights in the pharmacological actions of methotrexate in the treatment of rheumatoid arthritis. Rheumatology (Oxford). 2008 Mar;47(3):249-55. PMID: 18045808.

" T, Repr., Xi "UN number: 2811     Class: 6.1     Packing Group: III

Proper shipping name: Toxic solid, oxidizing, n.o.s. (Methotrexate hydrate)"

LKT S7717 Sterigmatocystin 5 mg 221 Mycotoxin produced by Aspergillus; carcinogen. 10048-13-2 ≥98% 324.28 C18H12O6 COC1=C2C(=C3C4C=COC4OC3=C1)OC5=C(C2=O)C(=CC=C5)O Ambient 4°C DMSO, Methanol, Ethanol, Acetone. "Zhang D, Cui Y, Shen H, et al. Sterigmatocystin-induced DNA damage triggers G2 arrest via an ATM/p53-related pathway in human gastric epithelium GES-1 cells in vitro. PLoS One. 2013 May 21;8(5):e65044. PMID: 23705030.

 

Xing X, Wang J, Xing LX, et al. Involvement of MAPK and PI3K signaling pathway in sterigmatocystin-induced G2 phase arrest in human gastric epithelium cells. Mol Nutr Food Res. 2011 May;55(5):749-60. PMID: 21287681.

 

Delgado-Virgen F, Guzman-de-Peña D. Mechanism of Sterigmatocystin Biosynthesis Regulation by pH in Aspergillus nidulans. Braz J Microbiol. 2009 Oct;40(4):933-42. PMID: 24031444.

 

Sivakumar V, Thanislass J, Niranjali S, et al. Lipid peroxidation as a possible secondary mechanism of sterigmatocystin toxicity. Hum Exp Toxicol. 2001 Aug;20(8):398-403. PMID: 11727790.

" T, Carc. Cat. 3 "UN number: 3462     Class: 6.1     Packing Group: III

Proper shipping name: Toxins, extracted from living sources, solid, n.o.s. (Sterigmatocystin)"

LKT S7717 Sterigmatocystin 10 mg 398.6 Mycotoxin produced by Aspergillus; carcinogen. 10048-13-2 ≥98% 324.28 C18H12O6 COC1=C2C(=C3C4C=COC4OC3=C1)OC5=C(C2=O)C(=CC=C5)O Ambient 4°C DMSO, Methanol, Ethanol, Acetone. "Zhang D, Cui Y, Shen H, et al. Sterigmatocystin-induced DNA damage triggers G2 arrest via an ATM/p53-related pathway in human gastric epithelium GES-1 cells in vitro. PLoS One. 2013 May 21;8(5):e65044. PMID: 23705030.

 

Xing X, Wang J, Xing LX, et al. Involvement of MAPK and PI3K signaling pathway in sterigmatocystin-induced G2 phase arrest in human gastric epithelium cells. Mol Nutr Food Res. 2011 May;55(5):749-60. PMID: 21287681.

 

Delgado-Virgen F, Guzman-de-Peña D. Mechanism of Sterigmatocystin Biosynthesis Regulation by pH in Aspergillus nidulans. Braz J Microbiol. 2009 Oct;40(4):933-42. PMID: 24031444.

 

Sivakumar V, Thanislass J, Niranjali S, et al. Lipid peroxidation as a possible secondary mechanism of sterigmatocystin toxicity. Hum Exp Toxicol. 2001 Aug;20(8):398-403. PMID: 11727790.

" T, Carc. Cat. 3 "UN number: 3462     Class: 6.1     Packing Group: III

Proper shipping name: Toxins, extracted from living sources, solid, n.o.s. (Sterigmatocystin)"

LKT S7701 Stanozolol 1 g 66.9 Synthetic anabolic steroid derived from dihydrotestosterone; aromatase activator, PR agonist. (5α,17β)-17-Methyl-2'H-androst-2-eno[3,2-c]pyrazol-17-ol Strombia; Strombaject; Winstrol 10418-03-8 ≥98% 328.49 C21H32N2O C[C@]12CC[C@H]3[C@H]([C@@H]1CC[C@]2(C)O)CC[C@@H]4[C@@]3(CC5=C(C4)NN=C5)C Ambient Ambient Slightly soluble in water (1 mg/mL).  Soluble in ethanol (24 mg/mL). "Zhu SY, Li YH, Ma HM, et al. Stanozolol regulates proliferation of growth plate chondrocytes via activation of ERalpha in GnRHa-treated adolescent rats. J Pediatr Endocrinol Metab. 2011;24(5-6):275-81. PMID: 21823523.

 

Lionikas A, Blizard DA. Diverse effects of stanozolol in C57BL/6J and A/J mouse strains. Eur J Appl Physiol. 2008 Jun;103(3):333-41. PMID: 18350311.

 

Roselli CE. The effect of anabolic-androgenic steroids on aromatase activity and androgen receptor binding in the rat preoptic area. Brain Res. 1998 May 11;792(2):271-6. PMID: 9593936.

" Xn Not dangerous goods.

LKT S7701 Stanozolol 5 g 233.7 Synthetic anabolic steroid derived from dihydrotestosterone; aromatase activator, PR agonist. (5α,17β)-17-Methyl-2'H-androst-2-eno[3,2-c]pyrazol-17-ol Strombia; Strombaject; Winstrol 10418-03-8 ≥98% 328.49 C21H32N2O C[C@]12CC[C@H]3[C@H]([C@@H]1CC[C@]2(C)O)CC[C@@H]4[C@@]3(CC5=C(C4)NN=C5)C Ambient Ambient Slightly soluble in water (1 mg/mL).  Soluble in ethanol (24 mg/mL). "Zhu SY, Li YH, Ma HM, et al. Stanozolol regulates proliferation of growth plate chondrocytes via activation of ERalpha in GnRHa-treated adolescent rats. J Pediatr Endocrinol Metab. 2011;24(5-6):275-81. PMID: 21823523.

 

Lionikas A, Blizard DA. Diverse effects of stanozolol in C57BL/6J and A/J mouse strains. Eur J Appl Physiol. 2008 Jun;103(3):333-41. PMID: 18350311.

 

Roselli CE. The effect of anabolic-androgenic steroids on aromatase activity and androgen receptor binding in the rat preoptic area. Brain Res. 1998 May 11;792(2):271-6. PMID: 9593936.

" Xn Not dangerous goods.

LKT S7603 Stavudine 100 mg 84.3 Nucleoside (thymidine) analog; DNA chain terminator, RT inhibitor. 1-[(2R,5S)-5-(hydroxymethyl)-2,5-dihydrofuran-2-yl]-5-methylpyrimidine-2,4-dione d4T 3056-17-5 ≥98% 224.21 C10H12N2O4 CC1=CN(C(=O)NC1=O)C2C=CC(O2)CO Ambient Ambient Water "Sandhya B, Seetharamappa J. Probing the site-selective binding of an antiretroviral drug, Stavudine to calf thymus DNA. Nucleosides Nucleotides Nucleic Acids. 2013;32(12):660-9. PMID: 24328563.

 

Stankov MV, Panayotova-Dimitrova D, Leverkus M, et al. Thymidine analogues suppress autophagy and adipogenesis in cultured adipocytes. Antimicrob Agents Chemother. 2013 Jan;57(1):543-51. PMID: 23147731.

 

Stankov MV, Panayotova-Dimitrova D, Leverkus M, et al. Autophagy inhibition due to thymidine analogues as novel mechanism leading to hepatocyte dysfunction and lipid accumulation. AIDS. 2012 Oct 23;26(16):1995-2006. PMID: 22914580.

 

Naeger LK, Margot NA, Miller MD. ATP-dependent removal of nucleoside reverse transcriptase inhibitors by human immunodeficiency virus type 1 reverse transcriptase. Antimicrob Agents Chemother. 2002 Jul;46(7):2179-84. PMID: 12069972.

" Xi Not dangerous goods.

LKT S7603 Stavudine 250 mg 187.4 Nucleoside (thymidine) analog; DNA chain terminator, RT inhibitor. 1-[(2R,5S)-5-(hydroxymethyl)-2,5-dihydrofuran-2-yl]-5-methylpyrimidine-2,4-dione d4T 3056-17-5 ≥98% 224.21 C10H12N2O4 CC1=CN(C(=O)NC1=O)C2C=CC(O2)CO Ambient Ambient Water "Sandhya B, Seetharamappa J. Probing the site-selective binding of an antiretroviral drug, Stavudine to calf thymus DNA. Nucleosides Nucleotides Nucleic Acids. 2013;32(12):660-9. PMID: 24328563.

 

Stankov MV, Panayotova-Dimitrova D, Leverkus M, et al. Thymidine analogues suppress autophagy and adipogenesis in cultured adipocytes. Antimicrob Agents Chemother. 2013 Jan;57(1):543-51. PMID: 23147731.

 

Stankov MV, Panayotova-Dimitrova D, Leverkus M, et al. Autophagy inhibition due to thymidine analogues as novel mechanism leading to hepatocyte dysfunction and lipid accumulation. AIDS. 2012 Oct 23;26(16):1995-2006. PMID: 22914580.

 

Naeger LK, Margot NA, Miller MD. ATP-dependent removal of nucleoside reverse transcriptase inhibitors by human immunodeficiency virus type 1 reverse transcriptase. Antimicrob Agents Chemother. 2002 Jul;46(7):2179-84. PMID: 12069972.

" Xi Not dangerous goods.

LKT S7603 Stavudine 1 g 468.8 Nucleoside (thymidine) analog; DNA chain terminator, RT inhibitor. 1-[(2R,5S)-5-(hydroxymethyl)-2,5-dihydrofuran-2-yl]-5-methylpyrimidine-2,4-dione d4T 3056-17-5 ≥98% 224.21 C10H12N2O4 CC1=CN(C(=O)NC1=O)C2C=CC(O2)CO Ambient Ambient Water "Sandhya B, Seetharamappa J. Probing the site-selective binding of an antiretroviral drug, Stavudine to calf thymus DNA. Nucleosides Nucleotides Nucleic Acids. 2013;32(12):660-9. PMID: 24328563.

 

Stankov MV, Panayotova-Dimitrova D, Leverkus M, et al. Thymidine analogues suppress autophagy and adipogenesis in cultured adipocytes. Antimicrob Agents Chemother. 2013 Jan;57(1):543-51. PMID: 23147731.

 

Stankov MV, Panayotova-Dimitrova D, Leverkus M, et al. Autophagy inhibition due to thymidine analogues as novel mechanism leading to hepatocyte dysfunction and lipid accumulation. AIDS. 2012 Oct 23;26(16):1995-2006. PMID: 22914580.

 

Naeger LK, Margot NA, Miller MD. ATP-dependent removal of nucleoside reverse transcriptase inhibitors by human immunodeficiency virus type 1 reverse transcriptase. Antimicrob Agents Chemother. 2002 Jul;46(7):2179-84. PMID: 12069972.

" Xi Not dangerous goods.

LKT S7600 Staurosporine 1 mg 67.9 Alkaloid produced by Streptomyces, precursor in the synthesis of K252c; PKC and mammalian RNA splicing inhibitor. AM-2282 62996-74-1 ≥98% 466.5 C28H26N4O3 CC12C(C(CC(O1)N3C4=CC=CC=C4C5=C6C(=C7C8=CC=CC=C8N2C7=C53)CNC6=O)NC)OC Protect from light. Ambient -20°C Soluble in DMSO (50 mM), ethanol, or methanol (2 mg/mL). Insoluble in water. "Zhao C, Yin P, Mei C, et al. Down-regulation of DNA methyltransferase 3B in staurosporine-induced apoptosis and its mechanism in human hepatocarcinoma cell lines. Mol Cell Biochem. 2013 Apr;376(1-2):111-9. PMID: 23397112.

 

Bruges G, Betancourt M, March M, et al. Apoptotic-like activity of staurosporine in axenic cultures of Trypanosoma evansi. Rev Inst Med Trop Sao Paulo. 2012 Mar-Apr;54(2):103-8. PMID: 22499424.

 

Aukema KG, Chohan KK, Plourde GL, et al. Small molecule inhibitors of yeast pre-mRNA splicing. ACS Chem Biol. 2009 Sep 18;4(9):759-68. PMID: 19634919.

 

Tanramluk D, Schreyer A, Pitt WR, et al. On the origins of enzyme inhibitor selectivity and promiscuity: a case study of protein kinase binding to staurosporine. Chem Biol Drug Des. 2009 Jul;74(1):16-24. PMID: 19519740." Xn, T, Xi, Carc. Not dangerous goods.

LKT S7600 Staurosporine 5 mg 237.8 Alkaloid produced by Streptomyces, precursor in the synthesis of K252c; PKC and mammalian RNA splicing inhibitor. AM-2282 62996-74-1 ≥98% 466.5 C28H26N4O3 CC12C(C(CC(O1)N3C4=CC=CC=C4C5=C6C(=C7C8=CC=CC=C8N2C7=C53)CNC6=O)NC)OC Protect from light. Ambient -20°C Soluble in DMSO (50 mM), ethanol, or methanol (2 mg/mL). Insoluble in water. "Zhao C, Yin P, Mei C, et al. Down-regulation of DNA methyltransferase 3B in staurosporine-induced apoptosis and its mechanism in human hepatocarcinoma cell lines. Mol Cell Biochem. 2013 Apr;376(1-2):111-9. PMID: 23397112.

 

Bruges G, Betancourt M, March M, et al. Apoptotic-like activity of staurosporine in axenic cultures of Trypanosoma evansi. Rev Inst Med Trop Sao Paulo. 2012 Mar-Apr;54(2):103-8. PMID: 22499424.

 

Aukema KG, Chohan KK, Plourde GL, et al. Small molecule inhibitors of yeast pre-mRNA splicing. ACS Chem Biol. 2009 Sep 18;4(9):759-68. PMID: 19634919.

 

Tanramluk D, Schreyer A, Pitt WR, et al. On the origins of enzyme inhibitor selectivity and promiscuity: a case study of protein kinase binding to staurosporine. Chem Biol Drug Des. 2009 Jul;74(1):16-24. PMID: 19519740." Xn, T, Xi, Carc. Not dangerous goods.

LKT S7084 SR-101-Leu-CMK Red FLISPTM Assay Kit 25 Tests 270.9 Caspase activity measuring kit. Ambient 4°C Not dangerous goods.

LKT S7084 SR-101-Leu-CMK Red FLISPTM Assay Kit 100 Tests 774.9 Caspase activity measuring kit. Ambient 4°C Not dangerous goods.

LKT S7083 SR-101-Phe-CMK Red FLISPTM Assay Kit 25 Tests 270.9 Caspase activity measuring kit. Ambient 4°C

LKT S7083 SR-101-Phe-CMK Red FLISPTM Assay Kit 100 Tests 774.9 Caspase activity measuring kit. Ambient 4°C

LKT S7082 SR FLICA Caspase 9 Assay Kit 25 Tests 292.1 Caspase 9 activity measuring kit. Ambient 4°C Not dangerous goods.

LKT S7082 SR FLICA Caspase 9 Assay Kit 100 Tests 849.3 Caspase 9 activity measuring kit. Ambient 4°C Not dangerous goods.

LKT S7081 SR FLICA Caspases 3 and 7 Assay Kit 25 Tests 292.1 Caspases 3/7 activity measuring kit. Ambient 4°C Not dangerous goods.

LKT S7081 SR FLICA Caspases 3 and 7 Assay Kit 100 Tests 849.3 Caspases 3/7 activity measuring kit. Ambient 4°C Not dangerous goods.

LKT S7080 SR-FLICA Poly Caspases Assay Kit 25 Tests 292.1 Caspase activity measuring kit. Ambient 4°C Not dangerous goods.

LKT S7080 SR-FLICA Poly Caspases Assay Kit 100 Tests 849.3 Caspase activity measuring kit. Ambient 4°C Not dangerous goods.

LKT S6235 Spironolactone 1 g 67.9 Mineralocorticoid, aldosterone, AR antagonist, ENaC channel blocker, potential voltage-gated Ca2+ channel blocker. (7α,17α)-7-(Acetylthio)-17-hydroxy-3-oxopregn-4- ene-21-carboxylic acid γ-lactone Spirolactone; Spiroctan; Aldactone 52-01-7 ≥97% 416.57 C24H32O4S CC(=O)SC1CC2=CC(=O)CCC2(C3C1C4CCC5(C4(CC3)C)CCC(=O)O5)C Ambient Ambient Soluble in organic solvents. Practically insoluble in water. "Yancy CW, Jessup M, Bozkurt B, et al. 2013 ACCF/AHA guideline for the management of heart failure: a report of the American College of Cardiology Foundation/American Heart Association Task Force on Practice Guidelines. J Am Coll Cardiol. 2013 Oct 15;62(16):e147-239. PMID: 23747642.

 

Mann SJ, Parikh NS. A simplified mechanistic algorithm for treating resistant hypertension: efficacy in a retrospective study. J Clin Hypertens (Greenwich). 2012 Apr;14(4):191-7. PMID: 22458739.

 

Nappi JM, Sieg A. Aldosterone and aldosterone receptor antagonists in patients with chronic heart failure. Vasc Health Risk Manag. 2011;7:353-63. PMID: 21731887.

" Repr., Carc. Not dangerous goods.

LKT S6235 Spironolactone 5 g 251.5 Mineralocorticoid, aldosterone, AR antagonist, ENaC channel blocker, potential voltage-gated Ca2+ channel blocker. (7α,17α)-7-(Acetylthio)-17-hydroxy-3-oxopregn-4- ene-21-carboxylic acid γ-lactone Spirolactone; Spiroctan; Aldactone 52-01-7 ≥97% 416.57 C24H32O4S CC(=O)SC1CC2=CC(=O)CCC2(C3C1C4CCC5(C4(CC3)C)CCC(=O)O5)C Ambient Ambient Soluble in organic solvents. Practically insoluble in water. "Yancy CW, Jessup M, Bozkurt B, et al. 2013 ACCF/AHA guideline for the management of heart failure: a report of the American College of Cardiology Foundation/American Heart Association Task Force on Practice Guidelines. J Am Coll Cardiol. 2013 Oct 15;62(16):e147-239. PMID: 23747642.

 

Mann SJ, Parikh NS. A simplified mechanistic algorithm for treating resistant hypertension: efficacy in a retrospective study. J Clin Hypertens (Greenwich). 2012 Apr;14(4):191-7. PMID: 22458739.

 

Nappi JM, Sieg A. Aldosterone and aldosterone receptor antagonists in patients with chronic heart failure. Vasc Health Risk Manag. 2011;7:353-63. PMID: 21731887.

" Repr., Carc. Not dangerous goods.

LKT S6234 Spiramycin Embonate 1 g 96.7 Macrolide; protein synthesis inhibitor. Spiramycin 67-73%, embonic acid 27-33% Spira 200 67724-08-7 Spiramycin 67-73%, embonic acid 27-33% C23H16O6-Unspecified CC1CC=CC=CC(C(CC(C(C(C(CC(=O)O1)O)OC)OC2C(C(C(C(O2)C)OC3CC(C(C(O3)C)O)(C)O)N(C)C)O)CC=O)C)OC4CCC(C(O4)C)N(C)C.C1=CC=C2C(=C1)C=C(C(=C2CC3=C(C(=CC4=CC=CC=C43)C(=O)O)O)O)C(=O)O Ambient Ambient Soluble in most organic solvents "Kieffer F, Wallon M. Congenital toxoplasmosis. Handb Clin Neurol. 2013;112:1099-101. PMID: 23622316.

 

Büyükbaba Boral O, Sönmez Tamer G, Keçeli Özcan S, et al. Investigation of combined effectiveness of spiramycin and beta-glucan in mice models of acute toxoplasmosis and determination of IL-10, IL-12 and TNF-α levels. Mikrobiyol Bul. 2012 Jul;46(3):446-55. PMID: 22951656.

 

Chew WK, Segarra I, Ambu S, et al. Significant reduction of brain cysts caused by Toxoplasma gondii after treatment with spiramycin coadministered with metronidazole in a mouse model of chronic toxoplasmosis. Antimicrob Agents Chemother. 2012 Apr;56(4):1762-8. PMID: 22271863.

" Not dangerous goods.

LKT S6234 Spiramycin Embonate 5 g 290 Macrolide; protein synthesis inhibitor. Spiramycin 67-73%, embonic acid 27-33% Spira 200 67724-08-7 Spiramycin 67-73%, embonic acid 27-33% C23H16O6-Unspecified CC1CC=CC=CC(C(CC(C(C(C(CC(=O)O1)O)OC)OC2C(C(C(C(O2)C)OC3CC(C(C(O3)C)O)(C)O)N(C)C)O)CC=O)C)OC4CCC(C(O4)C)N(C)C.C1=CC=C2C(=C1)C=C(C(=C2CC3=C(C(=CC4=CC=CC=C43)C(=O)O)O)O)C(=O)O Ambient Ambient Soluble in most organic solvents "Kieffer F, Wallon M. Congenital toxoplasmosis. Handb Clin Neurol. 2013;112:1099-101. PMID: 23622316.

 

Büyükbaba Boral O, Sönmez Tamer G, Keçeli Özcan S, et al. Investigation of combined effectiveness of spiramycin and beta-glucan in mice models of acute toxoplasmosis and determination of IL-10, IL-12 and TNF-α levels. Mikrobiyol Bul. 2012 Jul;46(3):446-55. PMID: 22951656.

 

Chew WK, Segarra I, Ambu S, et al. Significant reduction of brain cysts caused by Toxoplasma gondii after treatment with spiramycin coadministered with metronidazole in a mouse model of chronic toxoplasmosis. Antimicrob Agents Chemother. 2012 Apr;56(4):1762-8. PMID: 22271863.

" Not dangerous goods.

LKT S6233 Spiramycin Hexanedioate 1 g 94.4 Macrolide; protein synthesis inhibitor. Spiramycin Adipate; stomamycin; suanovil 11034-40-5 ≥90% Ambient -20°C +68-73° Soluble in most organic solvents. "Kieffer F, Wallon M. Congenital toxoplasmosis. Handb Clin Neurol. 2013;112:1099-101. PMID: 23622316.

 

Büyükbaba Boral O, Sönmez Tamer G, Keçeli Özcan S, et al. Investigation of combined effectiveness of spiramycin and beta-glucan in mice models of acute toxoplasmosis and determination of IL-10, IL-12 and TNF-α levels. Mikrobiyol Bul. 2012 Jul;46(3):446-55. PMID: 22951656.

 

Chew WK, Segarra I, Ambu S, et al. Significant reduction of brain cysts caused by Toxoplasma gondii after treatment with spiramycin coadministered with metronidazole in a mouse model of chronic toxoplasmosis. Antimicrob Agents Chemother. 2012 Apr;56(4):1762-8. PMID: 22271863.

" Not dangerous goods.

LKT S6233 Spiramycin Hexanedioate 5 g 283.5 Macrolide; protein synthesis inhibitor. Spiramycin Adipate; stomamycin; suanovil 11034-40-5 ≥90% Ambient -20°C +68-73° Soluble in most organic solvents. "Kieffer F, Wallon M. Congenital toxoplasmosis. Handb Clin Neurol. 2013;112:1099-101. PMID: 23622316.

 

Büyükbaba Boral O, Sönmez Tamer G, Keçeli Özcan S, et al. Investigation of combined effectiveness of spiramycin and beta-glucan in mice models of acute toxoplasmosis and determination of IL-10, IL-12 and TNF-α levels. Mikrobiyol Bul. 2012 Jul;46(3):446-55. PMID: 22951656.

 

Chew WK, Segarra I, Ambu S, et al. Significant reduction of brain cysts caused by Toxoplasma gondii after treatment with spiramycin coadministered with metronidazole in a mouse model of chronic toxoplasmosis. Antimicrob Agents Chemother. 2012 Apr;56(4):1762-8. PMID: 22271863.

" Not dangerous goods.

LKT S6232 Spiramycin 1 g 73.5 Macrolide; protein synthesis inhibitor. ≥3900 IU/mg Selectomycin; rovamicina; rovamycin; RP-5337 8025-81-8 ≥3900 IU/mg 842.05 C43H74N2O14 CC1CC=CC=CC(C(CC(C(C(C(CC(=O)O1)O)OC)OC2C(C(C(C(O2)C)OC3CC(C(C(O3)C)O)(C)O)N(C)C)O)CC=O)C)OC4CCC(C(O4)C)N(C)C Ambient Ambient Slightly soluble in water.  Soluble in most organic solvents, DMSO. "Kieffer F, Wallon M. Congenital toxoplasmosis. Handb Clin Neurol. 2013;112:1099-101. PMID: 23622316.

 

Büyükbaba Boral O, Sönmez Tamer G, Keçeli Özcan S, et al. Investigation of combined effectiveness of spiramycin and beta-glucan in mice models of acute toxoplasmosis and determination of IL-10, IL-12 and TNF-α levels. Mikrobiyol Bul. 2012 Jul;46(3):446-55. PMID: 22951656.

 

Chew WK, Segarra I, Ambu S, et al. Significant reduction of brain cysts caused by Toxoplasma gondii after treatment with spiramycin coadministered with metronidazole in a mouse model of chronic toxoplasmosis. Antimicrob Agents Chemother. 2012 Apr;56(4):1762-8. PMID: 22271863.

" None Not dangerous goods.

LKT S6232 Spiramycin 5 g 252.1 Macrolide; protein synthesis inhibitor. ≥3900 IU/mg Selectomycin; rovamicina; rovamycin; RP-5337 8025-81-8 ≥3900 IU/mg 842.05 C43H74N2O14 CC1CC=CC=CC(C(CC(C(C(C(CC(=O)O1)O)OC)OC2C(C(C(C(O2)C)OC3CC(C(C(O3)C)O)(C)O)N(C)C)O)CC=O)C)OC4CCC(C(O4)C)N(C)C Ambient Ambient Slightly soluble in water.  Soluble in most organic solvents, DMSO. "Kieffer F, Wallon M. Congenital toxoplasmosis. Handb Clin Neurol. 2013;112:1099-101. PMID: 23622316.

 

Büyükbaba Boral O, Sönmez Tamer G, Keçeli Özcan S, et al. Investigation of combined effectiveness of spiramycin and beta-glucan in mice models of acute toxoplasmosis and determination of IL-10, IL-12 and TNF-α levels. Mikrobiyol Bul. 2012 Jul;46(3):446-55. PMID: 22951656.

 

Chew WK, Segarra I, Ambu S, et al. Significant reduction of brain cysts caused by Toxoplasma gondii after treatment with spiramycin coadministered with metronidazole in a mouse model of chronic toxoplasmosis. Antimicrob Agents Chemother. 2012 Apr;56(4):1762-8. PMID: 22271863.

" None Not dangerous goods.

LKT S6168 Spirapril Hydrochloride 100 mg 288.8 ACE inhibitor. 94841-17-5 503.07 C22H30N2O5S2 HCl CCOC(=O)C(CCC1=CC=CC=C1)NC(C)C(=O)N2CC3(CC2C(=O)O)SCCS3 Ambient Ambient "Noble S, Sorkin EM. Spirapril. A preliminary review of its pharmacology and therapeutic efficacy in the treatment of hypertension. Drugs. 1995 May;49(5):750-66. PMID: 7601014.

 

Sybertz EJ, Watkins RW, Ahn HS, et al. Pharmacologic, metabolic, and toxicologic profile of spirapril (SCH 33844), a new angiotensin converting inhibitor. J Cardiovasc Pharmacol. 1987;10 Suppl 7:S105-8. PMID: 2485040.

" Not dangerous goods.

LKT S6168 Spirapril Hydrochloride 250 mg 609 ACE inhibitor. 94841-17-5 503.07 C22H30N2O5S2 HCl CCOC(=O)C(CCC1=CC=CC=C1)NC(C)C(=O)N2CC3(CC2C(=O)O)SCCS3 Ambient Ambient "Noble S, Sorkin EM. Spirapril. A preliminary review of its pharmacology and therapeutic efficacy in the treatment of hypertension. Drugs. 1995 May;49(5):750-66. PMID: 7601014.

 

Sybertz EJ, Watkins RW, Ahn HS, et al. Pharmacologic, metabolic, and toxicologic profile of spirapril (SCH 33844), a new angiotensin converting inhibitor. J Cardiovasc Pharmacol. 1987;10 Suppl 7:S105-8. PMID: 2485040.

" Not dangerous goods.

LKT S6134 Spinorphin, cow 5 mg 312.3 Endogenous heptapeptide; P2X3 and N-formylpeptide antagonist, ACE, enkephalinase, aminopeptidase IV, neutral endopeptidase, DPP3 inhibitor. 137201-62-8 ≥95% 877.06 C45H64N8O10 CC(C)CC(C(=O)NC(C(C)C)C(=O)NC(C(C)C)C(=O)NC(CC1=CC=C(C=C1)O)C(=O)N2CCCC2C(=O)NC(CC3=CNC4=CC=CC=C43)C(=O)NC(C(C)O)C(=O)O)N Ambient -20°C "Thanawala V, Kadam VJ, Ghosh R. Enkephalinase inhibitors: potential agents for the management of pain. Curr Drug Targets. 2008 Oct;9(10):887-94. PMID: 18855623.

 

Jung KY, Moon HD, Lee GE, et al. Structure-activity relationship studies of spinorphin as a potent and selective human P2X(3) receptor antagonist. J Med Chem. 2007 Sep 6;50(18):4543-7. PMID: 17676725.

 

Yamamoto Y, Ono H, Ueda A, et al. Spinorphin as an endogenous inhibitor of enkephalin-degrading enzymes: roles in pain and inflammation. Curr Protein Pept Sci. 2002 Dec;3(6):587-99. PMID: 12470213.

 

Liang TS, Gao JL, Fatemi O, et al. The endogenous opioid spinorphin blocks fMet-Leu-Phe-induced neutrophil chemotaxis by acting as a specific antagonist at the N-formylpeptide receptor subtype FPR. J Immunol. 2001 Dec 1;167(11):6609-14. PMID: 11714831.

 

Nishimura K, Hazato T. Isolation and identification of an endogenous inhibitor of enkephalin-degrading enzymes from bovine spinal cord. Biochem Biophys Res Commun. 1993 Jul 30;194(2):713-9. PMID: 8343155.

"

LKT S6134 Spinorphin, cow 10 mg 531.1 Endogenous heptapeptide; P2X3 and N-formylpeptide antagonist, ACE, enkephalinase, aminopeptidase IV, neutral endopeptidase, DPP3 inhibitor. 137201-62-8 ≥95% 877.06 C45H64N8O10 CC(C)CC(C(=O)NC(C(C)C)C(=O)NC(C(C)C)C(=O)NC(CC1=CC=C(C=C1)O)C(=O)N2CCCC2C(=O)NC(CC3=CNC4=CC=CC=C43)C(=O)NC(C(C)O)C(=O)O)N Ambient -20°C "Thanawala V, Kadam VJ, Ghosh R. Enkephalinase inhibitors: potential agents for the management of pain. Curr Drug Targets. 2008 Oct;9(10):887-94. PMID: 18855623.

 

Jung KY, Moon HD, Lee GE, et al. Structure-activity relationship studies of spinorphin as a potent and selective human P2X(3) receptor antagonist. J Med Chem. 2007 Sep 6;50(18):4543-7. PMID: 17676725.

 

Yamamoto Y, Ono H, Ueda A, et al. Spinorphin as an endogenous inhibitor of enkephalin-degrading enzymes: roles in pain and inflammation. Curr Protein Pept Sci. 2002 Dec;3(6):587-99. PMID: 12470213.

 

Liang TS, Gao JL, Fatemi O, et al. The endogenous opioid spinorphin blocks fMet-Leu-Phe-induced neutrophil chemotaxis by acting as a specific antagonist at the N-formylpeptide receptor subtype FPR. J Immunol. 2001 Dec 1;167(11):6609-14. PMID: 11714831.

 

Nishimura K, Hazato T. Isolation and identification of an endogenous inhibitor of enkephalin-degrading enzymes from bovine spinal cord. Biochem Biophys Res Commun. 1993 Jul 30;194(2):713-9. PMID: 8343155.

"

LKT S6134 Spinorphin, cow 25 mg 936.1 Endogenous heptapeptide; P2X3 and N-formylpeptide antagonist, ACE, enkephalinase, aminopeptidase IV, neutral endopeptidase, DPP3 inhibitor. 137201-62-8 ≥95% 877.06 C45H64N8O10 CC(C)CC(C(=O)NC(C(C)C)C(=O)NC(C(C)C)C(=O)NC(CC1=CC=C(C=C1)O)C(=O)N2CCCC2C(=O)NC(CC3=CNC4=CC=CC=C43)C(=O)NC(C(C)O)C(=O)O)N Ambient -20°C "Thanawala V, Kadam VJ, Ghosh R. Enkephalinase inhibitors: potential agents for the management of pain. Curr Drug Targets. 2008 Oct;9(10):887-94. PMID: 18855623.

 

Jung KY, Moon HD, Lee GE, et al. Structure-activity relationship studies of spinorphin as a potent and selective human P2X(3) receptor antagonist. J Med Chem. 2007 Sep 6;50(18):4543-7. PMID: 17676725.

 

Yamamoto Y, Ono H, Ueda A, et al. Spinorphin as an endogenous inhibitor of enkephalin-degrading enzymes: roles in pain and inflammation. Curr Protein Pept Sci. 2002 Dec;3(6):587-99. PMID: 12470213.

 

Liang TS, Gao JL, Fatemi O, et al. The endogenous opioid spinorphin blocks fMet-Leu-Phe-induced neutrophil chemotaxis by acting as a specific antagonist at the N-formylpeptide receptor subtype FPR. J Immunol. 2001 Dec 1;167(11):6609-14. PMID: 11714831.

 

Nishimura K, Hazato T. Isolation and identification of an endogenous inhibitor of enkephalin-degrading enzymes from bovine spinal cord. Biochem Biophys Res Commun. 1993 Jul 30;194(2):713-9. PMID: 8343155.

"

LKT S6131 N,N-Dimethyl-Sphingosine 5 mg 74.8 PP2A activator, Sphk1 and PKC inhibitor. "4-Octadecene-1,3-diol, 2-(dimethylamino)-, (R-(R*,S*-(E)))- 

" N,N-Dimethyl-D-erythro-sphingosine 119567-63-4 ≥98% 327.5 C20H41NO2 CCCCCCCCCCCCCC=CC(C(CO)N(C)C)O Ambient -20°C Soluble in DMSO or ethanol. "Rosa R, Marciano R, Malapelle U, et al. Sphingosine kinase 1 overexpression contributes to cetuximab resistance in human colorectal cancer models. Clin Cancer Res. 2013 Jan 1;19(1):138-47. PMID: 23166225.

 

Habrukowich C, Han DK, Le A, et al. Sphingosine interaction with acidic leucine-rich nuclear phosphoprotein-32A (ANP32A) regulates PP2A activity and cyclooxygenase (COX)-2 expression in human endothelial cells. J Biol Chem. 2010 Aug 27;285(35):26825-31. PMID: 20558741.

 

Endo K, Igarashi Y, Nisar M, et al. Cell membrane signaling as target in cancer therapy: inhibitory effect of N,N-dimethyl and N,N,N-trimethyl sphingosine derivatives on in vitro and in vivo growth of human tumor cells in nude mice. Cancer Res. 1991 Mar 15;51(6):1613-8. PMID: 1998952.

" None Not dangerous goods.

LKT S6130 Sphingosine-1-Phosphate 1 mg 186.8 Endogenous sphingolipid involved in cell signaling; sphingosine-1-phosphate agonist, potential HDAC inhibitor. "4-Octadecene-1,3-diol, 2-amino-, 1-(dihydrogen phosphate), (2S,3R,4E)- 

" D-erythro-Sphingosine-1-phosphate 26993-30-6 ≥98% 379.47 C18H38NO5P CCCCCCCCCCCCCC=CC(C(COP(=O)(O)O)N)O Ambient -20°C Soluble in methanol. "Czubowicz K, Cieślik M, Pyszko J, et al. Sphingosine-1-Phosphate and Its Effect on Glucose Deprivation/Glucose Reload Stress: From Gene Expression to Neuronal Survival. Mol Neurobiol. 2014 Jul 24. [Epub ahead of print]. PMID: 25056275.

 

Mahajan-Thakur S, Sostmann BD, Fender AC, et al. Sphingosine-1-phosphate induces thrombin receptor PAR-4 expression to enhance cell migration and COX-2 formation in human monocytes. J Leukoc Biol. 2014 Jul 2. [Epub ahead of print]. PMID: 24990321.

 

Nguyen-Tran DH, Hait NC, Sperber H, et al. Molecular mechanism of sphingosine-1-phosphate action in Duchenne muscular dystrophy. Dis Model Mech. 2014 Jan;7(1):41-54. PMID: 24077965.

 

Zelinski MB, Murphy MK, Lawson MS, et al. In vivo delivery of FTY720 prevents radiation-induced ovarian failure and infertility in adult female nonhuman primates. Fertil Steril. 2011 Mar 15;95(4):1440-5.e1-7. PMID: 21316047.

" Xi Not dangerous goods.

LKT S6129 D-Sphingosine 5 mg 82.3 Endogenous component of sphingolipids; PKC inhibitor. (2S,3R,4E)-2-Amino-4-octadecene-1,3-diol Sphingosine; 4-Sphingenine 123-78-4 ≥98% 299.49 C18H37NO2 CCCCCCCCCCCCCC=CC(C(CO)N)O Ambient -20°C Soluble in chloroform, DMSO. Insoluble  in ethanol, acetone, water. "Fischer CL, Drake DR, Dawson DV, et al. Antibacterial activity of sphingoid bases and fatty acids against Gram-positive and Gram-negative bacteria. Antimicrob Agents Chemother. 2012 Mar;56(3):1157-61. PMID: 22155833.

 

Huang Y, Zhang XY, Chen HL. Regulation of Phospholipase D Activity in Human Hepatocacinoma Cells by Protein Kinases and D-sphingosine. Sheng Wu Hua Xue Yu Sheng Wu Wu Li Xue Bao (Shanghai). 1999;31(5):572-576. PMID: 12114973.

" Not dangerous goods.

LKT S6129 D-Sphingosine 25 mg 307.5 Endogenous component of sphingolipids; PKC inhibitor. (2S,3R,4E)-2-Amino-4-octadecene-1,3-diol Sphingosine; 4-Sphingenine 123-78-4 ≥98% 299.49 C18H37NO2 CCCCCCCCCCCCCC=CC(C(CO)N)O Ambient -20°C Soluble in chloroform, DMSO. Insoluble  in ethanol, acetone, water. "Fischer CL, Drake DR, Dawson DV, et al. Antibacterial activity of sphingoid bases and fatty acids against Gram-positive and Gram-negative bacteria. Antimicrob Agents Chemother. 2012 Mar;56(3):1157-61. PMID: 22155833.

 

Huang Y, Zhang XY, Chen HL. Regulation of Phospholipase D Activity in Human Hepatocacinoma Cells by Protein Kinases and D-sphingosine. Sheng Wu Hua Xue Yu Sheng Wu Wu Li Xue Bao (Shanghai). 1999;31(5):572-576. PMID: 12114973.

" Not dangerous goods.

LKT S6019 Speract 1 mg 96 Peptide, derived from egg outer envelope; K+ channel activator, speract SRCR agonist. Sperm-activating Peptide H-1 76901-59-2 ≥95% 891.94 C38H57N11O14 CC(C)CC(C(=O)NC(CC(=O)N)C(=O)NCC(=O)NCC(=O)NCC(=O)NC(C(C)C)C(=O)NCC(=O)O)NC(=O)C(CC(=O)O)NC(=O)C(CC1=CC=CC=C1)NC(=O)CN Ambient -20°C "Guerrero A, Nishigaki T, Carneiro J, et al. Tuning sperm chemotaxis by calcium burst timing. Dev Biol. 2010 Aug 1;344(1):52-65. PMID: 20435032.

 

Darszon A, Treviño CL, Wood C, et al. Ion channels in sperm motility and capacitation. Soc Reprod Fertil Suppl. 2007;65:229-44. PMID: 17644965.

 

Wood CD, Nishigaki T, Tatsu Y, et al. Altering the speract-induced ion permeability changes that generate flagellar Ca2+ spikes regulates their kinetics and sea urchin sperm motility. Dev Biol. 2007 Jun 15;306(2):525-37. PMID: 17467684.

 

Rodríguez E, Darszon A. Intracellular sodium changes during the speract response and the acrosome reaction in sea urchin sperm. J Physiol. 2003 Jan 1;546(Pt 1):89-100. PMID: 12509481.

 

Cardullo RA, Herrick SB, Peterson MJ, et al. Speract receptors are localized on sea urchin sperm flagella using a fluorescent peptide analog. Dev Biol. 1994 Apr;162(2):600-7. PMID: 8150218.

 

Babcock DF, Bosma MM, Battaglia DE, et al. Early persistent activation of sperm K+ channels by the egg peptide speract. Proc Natl Acad Sci U S A. 1992 Jul 1;89(13):6001-5. PMID: 1631086.

"

LKT S6019 Speract 2 mg 162 Peptide, derived from egg outer envelope; K+ channel activator, speract SRCR agonist. Sperm-activating Peptide H-1 76901-59-2 ≥95% 891.94 C38H57N11O14 CC(C)CC(C(=O)NC(CC(=O)N)C(=O)NCC(=O)NCC(=O)NCC(=O)NC(C(C)C)C(=O)NCC(=O)O)NC(=O)C(CC(=O)O)NC(=O)C(CC1=CC=CC=C1)NC(=O)CN Ambient -20°C "Guerrero A, Nishigaki T, Carneiro J, et al. Tuning sperm chemotaxis by calcium burst timing. Dev Biol. 2010 Aug 1;344(1):52-65. PMID: 20435032.

 

Darszon A, Treviño CL, Wood C, et al. Ion channels in sperm motility and capacitation. Soc Reprod Fertil Suppl. 2007;65:229-44. PMID: 17644965.

 

Wood CD, Nishigaki T, Tatsu Y, et al. Altering the speract-induced ion permeability changes that generate flagellar Ca2+ spikes regulates their kinetics and sea urchin sperm motility. Dev Biol. 2007 Jun 15;306(2):525-37. PMID: 17467684.

 

Rodríguez E, Darszon A. Intracellular sodium changes during the speract response and the acrosome reaction in sea urchin sperm. J Physiol. 2003 Jan 1;546(Pt 1):89-100. PMID: 12509481.

 

Cardullo RA, Herrick SB, Peterson MJ, et al. Speract receptors are localized on sea urchin sperm flagella using a fluorescent peptide analog. Dev Biol. 1994 Apr;162(2):600-7. PMID: 8150218.

 

Babcock DF, Bosma MM, Battaglia DE, et al. Early persistent activation of sperm K+ channels by the egg peptide speract. Proc Natl Acad Sci U S A. 1992 Jul 1;89(13):6001-5. PMID: 1631086.

"

LKT S6019 Speract 5 mg 287.9 Peptide, derived from egg outer envelope; K+ channel activator, speract SRCR agonist. Sperm-activating Peptide H-1 76901-59-2 ≥95% 891.94 C38H57N11O14 CC(C)CC(C(=O)NC(CC(=O)N)C(=O)NCC(=O)NCC(=O)NCC(=O)NC(C(C)C)C(=O)NCC(=O)O)NC(=O)C(CC(=O)O)NC(=O)C(CC1=CC=CC=C1)NC(=O)CN Ambient -20°C "Guerrero A, Nishigaki T, Carneiro J, et al. Tuning sperm chemotaxis by calcium burst timing. Dev Biol. 2010 Aug 1;344(1):52-65. PMID: 20435032.

 

Darszon A, Treviño CL, Wood C, et al. Ion channels in sperm motility and capacitation. Soc Reprod Fertil Suppl. 2007;65:229-44. PMID: 17644965.

 

Wood CD, Nishigaki T, Tatsu Y, et al. Altering the speract-induced ion permeability changes that generate flagellar Ca2+ spikes regulates their kinetics and sea urchin sperm motility. Dev Biol. 2007 Jun 15;306(2):525-37. PMID: 17467684.

 

Rodríguez E, Darszon A. Intracellular sodium changes during the speract response and the acrosome reaction in sea urchin sperm. J Physiol. 2003 Jan 1;546(Pt 1):89-100. PMID: 12509481.

 

Cardullo RA, Herrick SB, Peterson MJ, et al. Speract receptors are localized on sea urchin sperm flagella using a fluorescent peptide analog. Dev Biol. 1994 Apr;162(2):600-7. PMID: 8150218.

 

Babcock DF, Bosma MM, Battaglia DE, et al. Early persistent activation of sperm K+ channels by the egg peptide speract. Proc Natl Acad Sci U S A. 1992 Jul 1;89(13):6001-5. PMID: 1631086.

"

LKT S6018 Spectinomycin Dihydrochloride Pentahydrate 5 g 61.1 Aminocyclitol; protein synthesis inhibitor. Spectam; Spectinomycin dihydrochloride; Stanilo 22189-32-8 ≥96% 495.25 C14H24N2O7 2HCl 5H2O CC1CC(=O)C2(C(O1)OC3C(C(C(C(C3O2)NC)O)NC)O)O Ambient 4°C Soluble in water to 100 mM. methanol, propylene glycol, and formamid. DMSO to 99 mg/mL, PBS to 10 mg/mL. "Ilina EN, Malakhova MV, Bodoev IN, et al. Mutation in ribosomal protein S5 leads to spectinomycin resistance in Neisseria gonorrhoeae. Front Microbiol. 2013 Jul 10;4:186. PMID: 23847609.

 

Kehrenberg C, Schwarz S. Mutations in 16S rRNA and ribosomal protein S5 associated with high-level spectinomycin resistance in Pasteurella multocida. Antimicrob Agents Chemother. 2007 Jun;51(6):2244-6. PMID: 17371823.

" Not dangerous goods.

LKT S6018 Spectinomycin Dihydrochloride Pentahydrate 25 g 136 Aminocyclitol; protein synthesis inhibitor. Spectam; Spectinomycin dihydrochloride; Stanilo 22189-32-8 ≥96% 495.25 C14H24N2O7 2HCl 5H2O CC1CC(=O)C2(C(O1)OC3C(C(C(C(C3O2)NC)O)NC)O)O Ambient 4°C Soluble in water to 100 mM. methanol, propylene glycol, and formamid. DMSO to 99 mg/mL, PBS to 10 mg/mL. "Ilina EN, Malakhova MV, Bodoev IN, et al. Mutation in ribosomal protein S5 leads to spectinomycin resistance in Neisseria gonorrhoeae. Front Microbiol. 2013 Jul 10;4:186. PMID: 23847609.

 

Kehrenberg C, Schwarz S. Mutations in 16S rRNA and ribosomal protein S5 associated with high-level spectinomycin resistance in Pasteurella multocida. Antimicrob Agents Chemother. 2007 Jun;51(6):2244-6. PMID: 17371823.

" Not dangerous goods.

LKT M1677 11-Methoxyyangonin 5 mg 186.6 Minor kavalactone originally found in Piper methysticum (kava plant). ≥98% 288.3 C16H16O5 Ambient -20°C Hänsel R, Klaproth L. Isolation of 11-methoxy-yangonin from the cava root. Arch Pharm Ber Dtsch Pharm Ges. 1966 Jun;299(6):503-6. PMID: 5228634. Not dangerous goods.

LKT M1677 11-Methoxyyangonin 10 mg 288.3 Minor kavalactone originally found in Piper methysticum (kava plant). ≥98% 288.3 C16H16O5 Ambient -20°C Hänsel R, Klaproth L. Isolation of 11-methoxy-yangonin from the cava root. Arch Pharm Ber Dtsch Pharm Ges. 1966 Jun;299(6):503-6. PMID: 5228634. Not dangerous goods.

LKT S6000 Sparfloxacin 500 mg 33.9 Fluoroquinolone; topoisomerase IV and bacterial DNA gyrase inhibitor. rel-5-Amino-1-cyclopropyl-7-[(3R,5S)-3,5-dimethyl-1-piperazinyl]-6,8-difluoro-1,4-dihydro-4-oxo-3- quinolinecarboxylic acid Zagam; Spara 110871-86-8 ≥98% 392.4 C19H22F2N4O3 CC1CN(CC(N1)C)C2=C(C3=C(C(=C2F)N)C(=O)C(=CN3C4CC4)C(=O)O)F Ambient Ambient Soluble in alcohol and chloroform.  Water(0.11 g/100 ml) "Gouvea LR, Garcia LS, Lachter DR, et al. Atypical fluoroquinolone gold(III) chelates as potential anticancer agents: relevance of DNA and protein interactions for their mechanism of action. Eur J Med Chem. 2012 Sep;55:67-73. PMID: 22835721.

 

Harding I, Simpson I. Fluoroquinolones: is there a different mechanism of action and resistance against Streptococcus pneumoniae? J Chemother. 2000 Oct;12 Suppl 4:7-15. PMID: 11131958.

 

Schentag JJ. Sparfloxacin: a review. Clin Ther. 2000 Apr;22(4):372-87; PMID: 10823360.

" Xi Not dangerous goods.

LKT S6000 Sparfloxacin 1 g 54.4 Fluoroquinolone; topoisomerase IV and bacterial DNA gyrase inhibitor. rel-5-Amino-1-cyclopropyl-7-[(3R,5S)-3,5-dimethyl-1-piperazinyl]-6,8-difluoro-1,4-dihydro-4-oxo-3- quinolinecarboxylic acid Zagam; Spara 110871-86-8 ≥98% 392.4 C19H22F2N4O3 CC1CN(CC(N1)C)C2=C(C3=C(C(=C2F)N)C(=O)C(=CN3C4CC4)C(=O)O)F Ambient Ambient Soluble in alcohol and chloroform.  Water(0.11 g/100 ml) "Gouvea LR, Garcia LS, Lachter DR, et al. Atypical fluoroquinolone gold(III) chelates as potential anticancer agents: relevance of DNA and protein interactions for their mechanism of action. Eur J Med Chem. 2012 Sep;55:67-73. PMID: 22835721.

 

Harding I, Simpson I. Fluoroquinolones: is there a different mechanism of action and resistance against Streptococcus pneumoniae? J Chemother. 2000 Oct;12 Suppl 4:7-15. PMID: 11131958.

 

Schentag JJ. Sparfloxacin: a review. Clin Ther. 2000 Apr;22(4):372-87; PMID: 10823360.

" Xi Not dangerous goods.

LKT M1678 2-Methoxyestradiol 5 mg 32.7 Estradiol metabolite; microtubule depolymerization inhibitor. 2-Hydroxyestradol 2-methyl ether; 2-Methoxyestradiol- 17β; Panzem 362-07-2 ≥98% 302.41 C19H26O3 CC12CCC3C(C1CCC2O)CCC4=CC(=C(C=C34)OC)O Ambient -20°C Soluble in DMSO or ethanol. "Yuan W, Yu Y, Li J, et al. Estrogen metabolite 2-methoxyestradiol prevents hypertension in deoxycorticosterone acetate-salt rats. Cardiovasc Drugs Ther. 2013 Feb;27(1):17-22. PMID: 23229845.

 

Salama SA, Diaz-Arrastia CR, Kilic GS, et al. 2-Methoxyestradiol causes functional repression of transforming growth factor β3 signaling by ameliorating Smad and non-Smad signaling pathways in immortalized uterine fibroid cells. Fertil Steril. 2012 Jul;98(1):178-84. PMID: 22579131.

 

Du B, Wang SY, Shi XF, et al. The effect of 2-methoxyestradiol liposome on growth inhibition, angiogenesis and expression of VEGF and Ki67 in mice bearing H22 hepatocellular carcinoma. Tumori. 2011 Sep-Oct;97(5):660-5. PMID: 22158500.

 

Garcia GE, Wisniewski HG, Lucia MS, et al. 2-Methoxyestradiol inhibits prostate tumor development in transgenic adenocarcinoma of mouse prostate: role of tumor necrosis factor-alpha-stimulated gene 6. Clin Cancer Res. 2006 Feb 1;12(3 Pt 1):980-8. PMID: 16467113.

 

Lakhani NJ, Sarkar MA, Venitz J, et al. 2-Methoxyestradiol, a promising anticancer agent. Pharmacotherapy. 2003 Feb;23(2):165-72. PMID: 12587805.

" T, Xi, Carc, Muta, Repr. "UN number: 2811     Class: 6.1     Packing Group: III

Proper shipping name: Toxic solid, organic, n.o.s. (2-Methoxyestradiol)"

LKT M1678 2-Methoxyestradiol 10 mg 61.1 Estradiol metabolite; microtubule depolymerization inhibitor. 2-Hydroxyestradol 2-methyl ether; 2-Methoxyestradiol- 17β; Panzem 362-07-2 ≥98% 302.41 C19H26O3 CC12CCC3C(C1CCC2O)CCC4=CC(=C(C=C34)OC)O Ambient -20°C Soluble in DMSO or ethanol. "Yuan W, Yu Y, Li J, et al. Estrogen metabolite 2-methoxyestradiol prevents hypertension in deoxycorticosterone acetate-salt rats. Cardiovasc Drugs Ther. 2013 Feb;27(1):17-22. PMID: 23229845.

 

Salama SA, Diaz-Arrastia CR, Kilic GS, et al. 2-Methoxyestradiol causes functional repression of transforming growth factor β3 signaling by ameliorating Smad and non-Smad signaling pathways in immortalized uterine fibroid cells. Fertil Steril. 2012 Jul;98(1):178-84. PMID: 22579131.

 

Du B, Wang SY, Shi XF, et al. The effect of 2-methoxyestradiol liposome on growth inhibition, angiogenesis and expression of VEGF and Ki67 in mice bearing H22 hepatocellular carcinoma. Tumori. 2011 Sep-Oct;97(5):660-5. PMID: 22158500.

 

Garcia GE, Wisniewski HG, Lucia MS, et al. 2-Methoxyestradiol inhibits prostate tumor development in transgenic adenocarcinoma of mouse prostate: role of tumor necrosis factor-alpha-stimulated gene 6. Clin Cancer Res. 2006 Feb 1;12(3 Pt 1):980-8. PMID: 16467113.

 

Lakhani NJ, Sarkar MA, Venitz J, et al. 2-Methoxyestradiol, a promising anticancer agent. Pharmacotherapy. 2003 Feb;23(2):165-72. PMID: 12587805.

" T, Xi, Carc, Muta, Repr. "UN number: 2811     Class: 6.1     Packing Group: III

Proper shipping name: Toxic solid, organic, n.o.s. (2-Methoxyestradiol)"

LKT M1678 2-Methoxyestradiol 50 mg 224.3 Estradiol metabolite; microtubule depolymerization inhibitor. 2-Hydroxyestradol 2-methyl ether; 2-Methoxyestradiol- 17β; Panzem 362-07-2 ≥98% 302.41 C19H26O3 CC12CCC3C(C1CCC2O)CCC4=CC(=C(C=C34)OC)O Ambient -20°C Soluble in DMSO or ethanol. "Yuan W, Yu Y, Li J, et al. Estrogen metabolite 2-methoxyestradiol prevents hypertension in deoxycorticosterone acetate-salt rats. Cardiovasc Drugs Ther. 2013 Feb;27(1):17-22. PMID: 23229845.

 

Salama SA, Diaz-Arrastia CR, Kilic GS, et al. 2-Methoxyestradiol causes functional repression of transforming growth factor β3 signaling by ameliorating Smad and non-Smad signaling pathways in immortalized uterine fibroid cells. Fertil Steril. 2012 Jul;98(1):178-84. PMID: 22579131.

 

Du B, Wang SY, Shi XF, et al. The effect of 2-methoxyestradiol liposome on growth inhibition, angiogenesis and expression of VEGF and Ki67 in mice bearing H22 hepatocellular carcinoma. Tumori. 2011 Sep-Oct;97(5):660-5. PMID: 22158500.

 

Garcia GE, Wisniewski HG, Lucia MS, et al. 2-Methoxyestradiol inhibits prostate tumor development in transgenic adenocarcinoma of mouse prostate: role of tumor necrosis factor-alpha-stimulated gene 6. Clin Cancer Res. 2006 Feb 1;12(3 Pt 1):980-8. PMID: 16467113.

 

Lakhani NJ, Sarkar MA, Venitz J, et al. 2-Methoxyestradiol, a promising anticancer agent. Pharmacotherapy. 2003 Feb;23(2):165-72. PMID: 12587805.

" T, Xi, Carc, Muta, Repr. "UN number: 2811     Class: 6.1     Packing Group: III

Proper shipping name: Toxic solid, organic, n.o.s. (2-Methoxyestradiol)"

LKT M1679 Methysticin 5 mg 186.6 Kavalactone originally found in Piper methysticum (kava plant). (6R)-6-[(1E)-2-(1,3-Benzodioxol-5-yl)ethenyl]-5,6- dihydro-4-methoxy-2H-pyran-2-one Kavahin; Kavatin 495-85-2 ≥98% 274.27 C15H14O5 COC1=CC(=O)OC(C1)C=CC2=CC3=C(C=C2)OCO3 Ambient -20°C Soluble in alcohol, ether or acetone. Practically insoluble in water. "Shaik AA, Hermanson DL, Xing C. Identification of methysticin as a potent and non-toxic NF-kappaB inhibitor from kava, potentially responsible for kava's chemopreventive activity. Bioorg Med Chem Lett. 2009 Oct 1;19(19):5732-6. PMID: 19716299.

 

Wruck CJ, Götz ME, Herdegen T, et al. Kavalactones protect neural cells against amyloid beta peptide-induced neurotoxicity via extracellular signal-regulated kinase 1/2-dependent nuclear factor erythroid 2-related factor 2 activation. Mol Pharmacol. 2008 Jun;73(6):1785-95. PMID: 18334601.

 

Xuan TD, Elzaawely AA, Fukuta M, et al. Herbicidal and Fungicidal Activities of Lactones in Kava (Piper methysticum). J Agric Food Chem. 2006 Feb 8;54(3):720-5. PMID: 16448174.

 

Magura EI, Kopanitsa MV, Gleitz J, et al. Kava extract ingredients, (+)-methysticin and (+/-)-kavain inhibit voltage-operated Na(+)-channels in rat CA1 hippocampal neurons. Neuroscience. 1997 Nov;81(2):345-51. Erratum in: Neuroscience 1998 May;84(1):323. PMID: 9300426.

" None Not dangerous goods.

LKT M1679 Methysticin 10 mg 288.3 Kavalactone originally found in Piper methysticum (kava plant). (6R)-6-[(1E)-2-(1,3-Benzodioxol-5-yl)ethenyl]-5,6- dihydro-4-methoxy-2H-pyran-2-one Kavahin; Kavatin 495-85-2 ≥98% 274.27 C15H14O5 COC1=CC(=O)OC(C1)C=CC2=CC3=C(C=C2)OCO3 Ambient -20°C Soluble in alcohol, ether or acetone. Practically insoluble in water. "Shaik AA, Hermanson DL, Xing C. Identification of methysticin as a potent and non-toxic NF-kappaB inhibitor from kava, potentially responsible for kava's chemopreventive activity. Bioorg Med Chem Lett. 2009 Oct 1;19(19):5732-6. PMID: 19716299.

 

Wruck CJ, Götz ME, Herdegen T, et al. Kavalactones protect neural cells against amyloid beta peptide-induced neurotoxicity via extracellular signal-regulated kinase 1/2-dependent nuclear factor erythroid 2-related factor 2 activation. Mol Pharmacol. 2008 Jun;73(6):1785-95. PMID: 18334601.

 

Xuan TD, Elzaawely AA, Fukuta M, et al. Herbicidal and Fungicidal Activities of Lactones in Kava (Piper methysticum). J Agric Food Chem. 2006 Feb 8;54(3):720-5. PMID: 16448174.

 

Magura EI, Kopanitsa MV, Gleitz J, et al. Kava extract ingredients, (+)-methysticin and (+/-)-kavain inhibit voltage-operated Na(+)-channels in rat CA1 hippocampal neurons. Neuroscience. 1997 Nov;81(2):345-51. Erratum in: Neuroscience 1998 May;84(1):323. PMID: 9300426.

" None Not dangerous goods.

LKT S5976 Sotalol Hydrochloride 25 mg 75 β-adrenergic antagonist, voltage-gated Na+ and K+ channel blocker. 959-24-0 ≥98% 308.82 C12H20N2O3S HCl CC(C)NCC(C1=CC=C(C=C1)NS(=O)(=O)C)O.Cl Ambient Ambient "Burashnikov A, Pourrier M, Gibson JK, et al. Rate-dependent effects of vernakalant in the isolated non-remodeled canine left atria are primarily due to block of the sodium channel: comparison with ranolazine and dl-sotalol. Circ Arrhythm Electrophysiol. 2012 Apr;5(2):400-8. PMID: 22322366.

 

Shah SA, Kluger J, White CM. Monotherapy versus combination therapy with class III antiarrhythmic agents to attenuate transmural dispersion of repolarization: a potential risk factor for torsade de pointes. Pharmacotherapy. 2007 Sep;27(9):1297-305. PMID: 17723083.

 

Singh BN, Singh SN, Reda DJ, et al. Amiodarone versus sotalol for atrial fibrillation. N Engl J Med. 2005 May 5;352(18):1861-72. PMID: 15872201.

 

Boriani G, Lubinski A, Capucci A, et al. A multicentre, double-blind randomized crossover comparative study on the efficacy and safety of dofetilide vs sotalol in patients with inducible sustained ventricular tachycardia and ischaemic heart disease. Eur Heart J. 2001 Dec;22(23):2180-91. PMID: 11913480.

 

 

Touboul P, Atallah G, Kirkorian G, et al. Clinical electrophysiology of intravenous sotalol, a beta-blocking drug with class III antiarrhythmic properties. Am Heart J. 1984 May;107(5 Pt 1):888-95. PMID: 6720518.

 

Giudicelli JF, Lhoste F, Boissier JR. Beta-adrenergic blockade and atrio--ventricular conduction impairment. Eur J Pharmacol. 1975 Apr;31(2):216-25. PMID: 238853.

" Xi Not dangerous goods.

LKT S5976 Sotalol Hydrochloride 100 mg 187.4 β-adrenergic antagonist, voltage-gated Na+ and K+ channel blocker. 959-24-0 ≥98% 308.82 C12H20N2O3S HCl CC(C)NCC(C1=CC=C(C=C1)NS(=O)(=O)C)O.Cl Ambient Ambient "Burashnikov A, Pourrier M, Gibson JK, et al. Rate-dependent effects of vernakalant in the isolated non-remodeled canine left atria are primarily due to block of the sodium channel: comparison with ranolazine and dl-sotalol. Circ Arrhythm Electrophysiol. 2012 Apr;5(2):400-8. PMID: 22322366.

 

Shah SA, Kluger J, White CM. Monotherapy versus combination therapy with class III antiarrhythmic agents to attenuate transmural dispersion of repolarization: a potential risk factor for torsade de pointes. Pharmacotherapy. 2007 Sep;27(9):1297-305. PMID: 17723083.

 

Singh BN, Singh SN, Reda DJ, et al. Amiodarone versus sotalol for atrial fibrillation. N Engl J Med. 2005 May 5;352(18):1861-72. PMID: 15872201.

 

Boriani G, Lubinski A, Capucci A, et al. A multicentre, double-blind randomized crossover comparative study on the efficacy and safety of dofetilide vs sotalol in patients with inducible sustained ventricular tachycardia and ischaemic heart disease. Eur Heart J. 2001 Dec;22(23):2180-91. PMID: 11913480.

 

 

Touboul P, Atallah G, Kirkorian G, et al. Clinical electrophysiology of intravenous sotalol, a beta-blocking drug with class III antiarrhythmic properties. Am Heart J. 1984 May;107(5 Pt 1):888-95. PMID: 6720518.

 

Giudicelli JF, Lhoste F, Boissier JR. Beta-adrenergic blockade and atrio--ventricular conduction impairment. Eur J Pharmacol. 1975 Apr;31(2):216-25. PMID: 238853.

" Xi Not dangerous goods.

LKT S5976 Sotalol Hydrochloride 250 mg 337.6 β-adrenergic antagonist, voltage-gated Na+ and K+ channel blocker. 959-24-0 ≥98% 308.82 C12H20N2O3S HCl CC(C)NCC(C1=CC=C(C=C1)NS(=O)(=O)C)O.Cl Ambient Ambient "Burashnikov A, Pourrier M, Gibson JK, et al. Rate-dependent effects of vernakalant in the isolated non-remodeled canine left atria are primarily due to block of the sodium channel: comparison with ranolazine and dl-sotalol. Circ Arrhythm Electrophysiol. 2012 Apr;5(2):400-8. PMID: 22322366.

 

Shah SA, Kluger J, White CM. Monotherapy versus combination therapy with class III antiarrhythmic agents to attenuate transmural dispersion of repolarization: a potential risk factor for torsade de pointes. Pharmacotherapy. 2007 Sep;27(9):1297-305. PMID: 17723083.

 

Singh BN, Singh SN, Reda DJ, et al. Amiodarone versus sotalol for atrial fibrillation. N Engl J Med. 2005 May 5;352(18):1861-72. PMID: 15872201.

 

Boriani G, Lubinski A, Capucci A, et al. A multicentre, double-blind randomized crossover comparative study on the efficacy and safety of dofetilide vs sotalol in patients with inducible sustained ventricular tachycardia and ischaemic heart disease. Eur Heart J. 2001 Dec;22(23):2180-91. PMID: 11913480.

 

 

Touboul P, Atallah G, Kirkorian G, et al. Clinical electrophysiology of intravenous sotalol, a beta-blocking drug with class III antiarrhythmic properties. Am Heart J. 1984 May;107(5 Pt 1):888-95. PMID: 6720518.

 

Giudicelli JF, Lhoste F, Boissier JR. Beta-adrenergic blockade and atrio--ventricular conduction impairment. Eur J Pharmacol. 1975 Apr;31(2):216-25. PMID: 238853.

" Xi Not dangerous goods.

LKT M1680 5-Methoxyindole 1 g 37.8 Core structure of melatonin; potential PPARγ and 5-HT3 agonist. 5-Methoxy-1H-indole Femedol 1006-94-6 ≥98% 147.17 C9H9NO COC1=CC2=C(C=C1)NC=C2 Ambient Ambient Insoluble in water. "Czimmerer Z, Varga T, Poliska S, et al. Identification of novel markers of alternative activation and potential endogenous PPARγ ligand production mechanisms in human IL-4 stimulated differentiating macrophages. Immunobiology. 2012 Dec;217(12):1301-14. PMID: 22954708.

 

Koike T, Hoashi Y, Takai T, et al. 1,6-Dihydro-2H-indeno[5,4-b]furan derivatives: design, synthesis, and pharmacological characterization of a novel class of highly potent MT₂-selective agonists. J Med Chem. 2011 May 12;54(9):3436-44. PMID: 21473625.

" Not dangerous goods.

LKT M1680 5-Methoxyindole 5 g 125.8 Core structure of melatonin; potential PPARγ and 5-HT3 agonist. 5-Methoxy-1H-indole Femedol 1006-94-6 ≥98% 147.17 C9H9NO COC1=CC2=C(C=C1)NC=C2 Ambient Ambient Insoluble in water. "Czimmerer Z, Varga T, Poliska S, et al. Identification of novel markers of alternative activation and potential endogenous PPARγ ligand production mechanisms in human IL-4 stimulated differentiating macrophages. Immunobiology. 2012 Dec;217(12):1301-14. PMID: 22954708.

 

Koike T, Hoashi Y, Takai T, et al. 1,6-Dihydro-2H-indeno[5,4-b]furan derivatives: design, synthesis, and pharmacological characterization of a novel class of highly potent MT₂-selective agonists. J Med Chem. 2011 May 12;54(9):3436-44. PMID: 21473625.

" Not dangerous goods.

LKT M1685 Mevastatin 10 mg 28.6 Statin; HMG-CoA reductase inhibitor. (2S)-2-Methylbutanoic acid (1S,7S,8S,8aR)- 1,2,3,7,8,8a-hexahydro-7-methyl-8-[2-[(2R,4R)- tetrahydro-4-hydroxy-6-oxo-2H-pyran-2-yl]ethyl]-1- naphthalenyl ester Compactin; 6-demethylmevinolin; CS-500; ML-236B. 73573-88-3 ≥98% 390.51 C23H34O5 CCC(C)C(=O)OC1CCC=C2C1C(C(C=C2)C)CCC3CC(CC(=O)O3)O Ambient Ambient Soluble in DMSO, or ethanol. Insoluble in water. "Zhang S, Wang XL, Gan YH, et al. Activation of c-Jun N-terminal kinase is required for mevastatin-induced apoptosis of salivary adenoid cystic carcinoma cells. Anticancer Drugs. 2010 Aug;21(7):678-86. PMID: 20629200.

 

Thompson K, Rogers MJ. Statins prevent bisphosphonate-induced gamma,delta-T-cell proliferation and activation in vitro. J Bone Miner Res. 2004 Feb;19(2):278-88. PMID: 14969398.

 

Endo A, Kuroda M, Tsujita Y. ML-236A, ML-236B, and ML-236C, new inhibitors of cholesterogenesis produced by Penicillium citrinium. J Antibiot (Tokyo). 1976 Dec;29(12):1346-8. PMID: 1010803.

" None Not dangerous goods.

LKT M1685 Mevastatin 50 mg 109.2 Statin; HMG-CoA reductase inhibitor. (2S)-2-Methylbutanoic acid (1S,7S,8S,8aR)- 1,2,3,7,8,8a-hexahydro-7-methyl-8-[2-[(2R,4R)- tetrahydro-4-hydroxy-6-oxo-2H-pyran-2-yl]ethyl]-1- naphthalenyl ester Compactin; 6-demethylmevinolin; CS-500; ML-236B. 73573-88-3 ≥98% 390.51 C23H34O5 CCC(C)C(=O)OC1CCC=C2C1C(C(C=C2)C)CCC3CC(CC(=O)O3)O Ambient Ambient Soluble in DMSO, or ethanol. Insoluble in water. "Zhang S, Wang XL, Gan YH, et al. Activation of c-Jun N-terminal kinase is required for mevastatin-induced apoptosis of salivary adenoid cystic carcinoma cells. Anticancer Drugs. 2010 Aug;21(7):678-86. PMID: 20629200.

 

Thompson K, Rogers MJ. Statins prevent bisphosphonate-induced gamma,delta-T-cell proliferation and activation in vitro. J Bone Miner Res. 2004 Feb;19(2):278-88. PMID: 14969398.

 

Endo A, Kuroda M, Tsujita Y. ML-236A, ML-236B, and ML-236C, new inhibitors of cholesterogenesis produced by Penicillium citrinium. J Antibiot (Tokyo). 1976 Dec;29(12):1346-8. PMID: 1010803.

" None Not dangerous goods.

LKT M1687 Mevinolin 50 mg 95.1 Statin, naturally produced by mushrooms; HMG-CoA reductase inhibitor. (2S)-2-Methylbutanoic acid (1S,3R,7S,8S,8aR)-1,2,3,7,- 8,8a-hexahydro-3,7-dimethyl-8-[2-[(2R,4R)-tetrahydro-4-hydroxy-6-oxo-2H-pyran-2-yl]ethyl]-1-naphthalen- yl ester Mevacor; MK-803; Lovalip; Mevinacor; Mevlor; Sivlor; Lovastatin 75330-75-5 ≥97% 404.54 C24H36O5 CCC(C)C(=O)OC1CC(C=C2C1C(C(C=C2)C)CCC3CC(CC(=O)O3)O)C Ambient Ambient Soluble in acetone and chloroform. Slightly soluble in DMSO (8mg/mL),methanol and ethanol(6mg/mL). Insoluble in water. "Song X, Liu BC, Lu XY, et al. Lovastatin inhibits human B lymphoma cell proliferation by reducing intracellular ROS and TRPC6 expression.

 Biochim Biophys Acta. 2014 May;1843(5):894-901. PMID: 24518247.

 

Werner B, Dittmann S, Funke C, et al. Effect of lovastatin on coxsackievirus B3 infection in human endothelial cells. Inflamm Res. 2014 Apr;63(4):267-76. PMID: 24316867.

 

Gunde-Cimerman N, Cimerman A. Pleurotus fruiting bodies contain the inhibitor of 3-hydroxy-3-methylglutaryl-coenzyme A reductase-lovastatin. Exp Mycol. 1995 Mar;19(1):1-6. PMID: 7614366.

 

Alberts AW. Discovery, biochemistry and biology of lovastatin. Am J Cardiol. 1988 Nov 11;62(15):10J-15J. PMID: 3055919.

" Xi Not dangerous goods.

LKT M1687 Mevinolin 100 mg 169.9 Statin, naturally produced by mushrooms; HMG-CoA reductase inhibitor. (2S)-2-Methylbutanoic acid (1S,3R,7S,8S,8aR)-1,2,3,7,- 8,8a-hexahydro-3,7-dimethyl-8-[2-[(2R,4R)-tetrahydro-4-hydroxy-6-oxo-2H-pyran-2-yl]ethyl]-1-naphthalen- yl ester Mevacor; MK-803; Lovalip; Mevinacor; Mevlor; Sivlor; Lovastatin 75330-75-5 ≥97% 404.54 C24H36O5 CCC(C)C(=O)OC1CC(C=C2C1C(C(C=C2)C)CCC3CC(CC(=O)O3)O)C Ambient Ambient Soluble in acetone and chloroform. Slightly soluble in DMSO (8mg/mL),methanol and ethanol(6mg/mL). Insoluble in water. "Song X, Liu BC, Lu XY, et al. Lovastatin inhibits human B lymphoma cell proliferation by reducing intracellular ROS and TRPC6 expression.

 Biochim Biophys Acta. 2014 May;1843(5):894-901. PMID: 24518247.

 

Werner B, Dittmann S, Funke C, et al. Effect of lovastatin on coxsackievirus B3 infection in human endothelial cells. Inflamm Res. 2014 Apr;63(4):267-76. PMID: 24316867.

 

Gunde-Cimerman N, Cimerman A. Pleurotus fruiting bodies contain the inhibitor of 3-hydroxy-3-methylglutaryl-coenzyme A reductase-lovastatin. Exp Mycol. 1995 Mar;19(1):1-6. PMID: 7614366.

 

Alberts AW. Discovery, biochemistry and biology of lovastatin. Am J Cardiol. 1988 Nov 11;62(15):10J-15J. PMID: 3055919.

" Xi Not dangerous goods.

LKT M1687 Mevinolin 500 mg 441.6 Statin, naturally produced by mushrooms; HMG-CoA reductase inhibitor. (2S)-2-Methylbutanoic acid (1S,3R,7S,8S,8aR)-1,2,3,7,- 8,8a-hexahydro-3,7-dimethyl-8-[2-[(2R,4R)-tetrahydro-4-hydroxy-6-oxo-2H-pyran-2-yl]ethyl]-1-naphthalen- yl ester Mevacor; MK-803; Lovalip; Mevinacor; Mevlor; Sivlor; Lovastatin 75330-75-5 ≥97% 404.54 C24H36O5 CCC(C)C(=O)OC1CC(C=C2C1C(C(C=C2)C)CCC3CC(CC(=O)O3)O)C Ambient Ambient Soluble in acetone and chloroform. Slightly soluble in DMSO (8mg/mL),methanol and ethanol(6mg/mL). Insoluble in water. "Song X, Liu BC, Lu XY, et al. Lovastatin inhibits human B lymphoma cell proliferation by reducing intracellular ROS and TRPC6 expression.

 Biochim Biophys Acta. 2014 May;1843(5):894-901. PMID: 24518247.

 

Werner B, Dittmann S, Funke C, et al. Effect of lovastatin on coxsackievirus B3 infection in human endothelial cells. Inflamm Res. 2014 Apr;63(4):267-76. PMID: 24316867.

 

Gunde-Cimerman N, Cimerman A. Pleurotus fruiting bodies contain the inhibitor of 3-hydroxy-3-methylglutaryl-coenzyme A reductase-lovastatin. Exp Mycol. 1995 Mar;19(1):1-6. PMID: 7614366.

 

Alberts AW. Discovery, biochemistry and biology of lovastatin. Am J Cardiol. 1988 Nov 11;62(15):10J-15J. PMID: 3055919.

" Xi Not dangerous goods.

LKT S5753 Somatostatin-28 (1-14) 1 mg 114 Endogenous neuropeptide hormone; somatostatin agonist, GABA modulator, P/Q-type, N-type, and L-type voltage-gated Ca2+ channel modulator. 79243-10-0 ≥95% 1528.72 C61H105N23O21S Ambient -20°C "Stumm R. Somatostatin receptor sst2 reduces Akt activity and aggravates hypoxic/ischemic death in cerebral cortical neurons. Neuropharmacology. 2014 Feb;77:249-56. PMID: 24157493.

 

Takahashi M, Takeda M, Matsumoto S. Somatostatin enhances tooth-pulp-evoked cervical dorsal horn neuronal activity in the rat via inhibition of GABAergic interneurons. Brain Res Bull. 2014 Jan;100:76-83. PMID: 24321530.

 

Albrecht A, Thiere M, Bergado-Acosta JR, et al. Circadian modulation of anxiety: a role for somatostatin in the amygdala. PLoS One. 2013 Dec 20;8(12):e84668. PMID: 24376834.

 

Kovac S, Walker MC. Neuropeptides in epilepsy. Neuropeptides. 2013 Dec;47(6):467-75. PMID: 24210141.

 

Begg DP, Woods SC. Interactions between the central nervous system and pancreatic islet secretions: a historical perspective. Adv Physiol Educ. 2013 Mar;37(1):53-60. PMID: 23471249.

 

Schwetz TA, Ustione A, Piston DW. Neuropeptide Y and somatostatin inhibit insulin secretion through different mechanisms. Am J Physiol Endocrinol Metab. 2013 Jan 15;304(2):E211-21. PMID: 23211512.

 

Kailey B, van de Bunt M, Cheley S, et al. SSTR2 is the functionally dominant somatostatin receptor in human pancreatic β- and α-cells. Am J Physiol Endocrinol Metab. 2012 Nov 1;303(9):E1107-16. PMID: 22932785.

" Not dangerous goods.

LKT S5753 Somatostatin-28 (1-14) 2 mg 348 Endogenous neuropeptide hormone; somatostatin agonist, GABA modulator, P/Q-type, N-type, and L-type voltage-gated Ca2+ channel modulator. 79243-10-0 ≥95% 1528.72 C61H105N23O21S Ambient -20°C "Stumm R. Somatostatin receptor sst2 reduces Akt activity and aggravates hypoxic/ischemic death in cerebral cortical neurons. Neuropharmacology. 2014 Feb;77:249-56. PMID: 24157493.

 

Takahashi M, Takeda M, Matsumoto S. Somatostatin enhances tooth-pulp-evoked cervical dorsal horn neuronal activity in the rat via inhibition of GABAergic interneurons. Brain Res Bull. 2014 Jan;100:76-83. PMID: 24321530.

 

Albrecht A, Thiere M, Bergado-Acosta JR, et al. Circadian modulation of anxiety: a role for somatostatin in the amygdala. PLoS One. 2013 Dec 20;8(12):e84668. PMID: 24376834.

 

Kovac S, Walker MC. Neuropeptides in epilepsy. Neuropeptides. 2013 Dec;47(6):467-75. PMID: 24210141.

 

Begg DP, Woods SC. Interactions between the central nervous system and pancreatic islet secretions: a historical perspective. Adv Physiol Educ. 2013 Mar;37(1):53-60. PMID: 23471249.

 

Schwetz TA, Ustione A, Piston DW. Neuropeptide Y and somatostatin inhibit insulin secretion through different mechanisms. Am J Physiol Endocrinol Metab. 2013 Jan 15;304(2):E211-21. PMID: 23211512.

 

Kailey B, van de Bunt M, Cheley S, et al. SSTR2 is the functionally dominant somatostatin receptor in human pancreatic β- and α-cells. Am J Physiol Endocrinol Metab. 2012 Nov 1;303(9):E1107-16. PMID: 22932785.

" Not dangerous goods.

LKT S5753 Somatostatin-28 (1-14) 5 mg 612.4 Endogenous neuropeptide hormone; somatostatin agonist, GABA modulator, P/Q-type, N-type, and L-type voltage-gated Ca2+ channel modulator. 79243-10-0 ≥95% 1528.72 C61H105N23O21S Ambient -20°C "Stumm R. Somatostatin receptor sst2 reduces Akt activity and aggravates hypoxic/ischemic death in cerebral cortical neurons. Neuropharmacology. 2014 Feb;77:249-56. PMID: 24157493.

 

Takahashi M, Takeda M, Matsumoto S. Somatostatin enhances tooth-pulp-evoked cervical dorsal horn neuronal activity in the rat via inhibition of GABAergic interneurons. Brain Res Bull. 2014 Jan;100:76-83. PMID: 24321530.

 

Albrecht A, Thiere M, Bergado-Acosta JR, et al. Circadian modulation of anxiety: a role for somatostatin in the amygdala. PLoS One. 2013 Dec 20;8(12):e84668. PMID: 24376834.

 

Kovac S, Walker MC. Neuropeptides in epilepsy. Neuropeptides. 2013 Dec;47(6):467-75. PMID: 24210141.

 

Begg DP, Woods SC. Interactions between the central nervous system and pancreatic islet secretions: a historical perspective. Adv Physiol Educ. 2013 Mar;37(1):53-60. PMID: 23471249.

 

Schwetz TA, Ustione A, Piston DW. Neuropeptide Y and somatostatin inhibit insulin secretion through different mechanisms. Am J Physiol Endocrinol Metab. 2013 Jan 15;304(2):E211-21. PMID: 23211512.

 

Kailey B, van de Bunt M, Cheley S, et al. SSTR2 is the functionally dominant somatostatin receptor in human pancreatic β- and α-cells. Am J Physiol Endocrinol Metab. 2012 Nov 1;303(9):E1107-16. PMID: 22932785.

" Not dangerous goods.

LKT S5752 Somatostatin-28 (1-12) 1 mg 204.1 Endogenous neuropeptide hormone; somatostatin agonist, GABA modulator, P/Q-type, N-type, and L-type voltage-gated Ca2+ channel modulator. 81286-16-0 ≥95% 1244.36 C49H81N17O19S1 CC(C(=O)NC(CCSC)C(=O)NC(C)C(=O)N1CCCC1C(=O)NC(CCCN=C(N)N)C(=O)NC(CCC(=O)O)C(=O)O)NC(=O)C2CCCN2C(=O)C(CC(=O)N)NC(=O)C(CO)NC(=O)C(CC(=O)N)NC(=O)C(C)NC(=O)C(CO)N Ambient -20°C "Stumm R. Somatostatin receptor sst2 reduces Akt activity and aggravates hypoxic/ischemic death in cerebral cortical neurons. Neuropharmacology. 2014 Feb;77:249-56. PMID: 24157493.

 

Takahashi M, Takeda M, Matsumoto S. Somatostatin enhances tooth-pulp-evoked cervical dorsal horn neuronal activity in the rat via inhibition of GABAergic interneurons. Brain Res Bull. 2014 Jan;100:76-83. PMID: 24321530.

 

Albrecht A, Thiere M, Bergado-Acosta JR, et al. Circadian modulation of anxiety: a role for somatostatin in the amygdala. PLoS One. 2013 Dec 20;8(12):e84668. PMID: 24376834.

 

Kovac S, Walker MC. Neuropeptides in epilepsy. Neuropeptides. 2013 Dec;47(6):467-75. PMID: 24210141.

 

Begg DP, Woods SC. Interactions between the central nervous system and pancreatic islet secretions: a historical perspective. Adv Physiol Educ. 2013 Mar;37(1):53-60. PMID: 23471249.

 

Schwetz TA, Ustione A, Piston DW. Neuropeptide Y and somatostatin inhibit insulin secretion through different mechanisms. Am J Physiol Endocrinol Metab. 2013 Jan 15;304(2):E211-21. PMID: 23211512.

 

Kailey B, van de Bunt M, Cheley S, et al. SSTR2 is the functionally dominant somatostatin receptor in human pancreatic β- and α-cells. Am J Physiol Endocrinol Metab. 2012 Nov 1;303(9):E1107-16. PMID: 22932785.

" Not dangerous goods.

LKT S5752 Somatostatin-28 (1-12) 2 mg 348 Endogenous neuropeptide hormone; somatostatin agonist, GABA modulator, P/Q-type, N-type, and L-type voltage-gated Ca2+ channel modulator. 81286-16-0 ≥95% 1244.36 C49H81N17O19S1 CC(C(=O)NC(CCSC)C(=O)NC(C)C(=O)N1CCCC1C(=O)NC(CCCN=C(N)N)C(=O)NC(CCC(=O)O)C(=O)O)NC(=O)C2CCCN2C(=O)C(CC(=O)N)NC(=O)C(CO)NC(=O)C(CC(=O)N)NC(=O)C(C)NC(=O)C(CO)N Ambient -20°C "Stumm R. Somatostatin receptor sst2 reduces Akt activity and aggravates hypoxic/ischemic death in cerebral cortical neurons. Neuropharmacology. 2014 Feb;77:249-56. PMID: 24157493.

 

Takahashi M, Takeda M, Matsumoto S. Somatostatin enhances tooth-pulp-evoked cervical dorsal horn neuronal activity in the rat via inhibition of GABAergic interneurons. Brain Res Bull. 2014 Jan;100:76-83. PMID: 24321530.

 

Albrecht A, Thiere M, Bergado-Acosta JR, et al. Circadian modulation of anxiety: a role for somatostatin in the amygdala. PLoS One. 2013 Dec 20;8(12):e84668. PMID: 24376834.

 

Kovac S, Walker MC. Neuropeptides in epilepsy. Neuropeptides. 2013 Dec;47(6):467-75. PMID: 24210141.

 

Begg DP, Woods SC. Interactions between the central nervous system and pancreatic islet secretions: a historical perspective. Adv Physiol Educ. 2013 Mar;37(1):53-60. PMID: 23471249.

 

Schwetz TA, Ustione A, Piston DW. Neuropeptide Y and somatostatin inhibit insulin secretion through different mechanisms. Am J Physiol Endocrinol Metab. 2013 Jan 15;304(2):E211-21. PMID: 23211512.

 

Kailey B, van de Bunt M, Cheley S, et al. SSTR2 is the functionally dominant somatostatin receptor in human pancreatic β- and α-cells. Am J Physiol Endocrinol Metab. 2012 Nov 1;303(9):E1107-16. PMID: 22932785.

" Not dangerous goods.

LKT S5752 Somatostatin-28 (1-12) 5 mg 612.4 Endogenous neuropeptide hormone; somatostatin agonist, GABA modulator, P/Q-type, N-type, and L-type voltage-gated Ca2+ channel modulator. 81286-16-0 ≥95% 1244.36 C49H81N17O19S1 CC(C(=O)NC(CCSC)C(=O)NC(C)C(=O)N1CCCC1C(=O)NC(CCCN=C(N)N)C(=O)NC(CCC(=O)O)C(=O)O)NC(=O)C2CCCN2C(=O)C(CC(=O)N)NC(=O)C(CO)NC(=O)C(CC(=O)N)NC(=O)C(C)NC(=O)C(CO)N Ambient -20°C "Stumm R. Somatostatin receptor sst2 reduces Akt activity and aggravates hypoxic/ischemic death in cerebral cortical neurons. Neuropharmacology. 2014 Feb;77:249-56. PMID: 24157493.

 

Takahashi M, Takeda M, Matsumoto S. Somatostatin enhances tooth-pulp-evoked cervical dorsal horn neuronal activity in the rat via inhibition of GABAergic interneurons. Brain Res Bull. 2014 Jan;100:76-83. PMID: 24321530.

 

Albrecht A, Thiere M, Bergado-Acosta JR, et al. Circadian modulation of anxiety: a role for somatostatin in the amygdala. PLoS One. 2013 Dec 20;8(12):e84668. PMID: 24376834.

 

Kovac S, Walker MC. Neuropeptides in epilepsy. Neuropeptides. 2013 Dec;47(6):467-75. PMID: 24210141.

 

Begg DP, Woods SC. Interactions between the central nervous system and pancreatic islet secretions: a historical perspective. Adv Physiol Educ. 2013 Mar;37(1):53-60. PMID: 23471249.

 

Schwetz TA, Ustione A, Piston DW. Neuropeptide Y and somatostatin inhibit insulin secretion through different mechanisms. Am J Physiol Endocrinol Metab. 2013 Jan 15;304(2):E211-21. PMID: 23211512.

 

Kailey B, van de Bunt M, Cheley S, et al. SSTR2 is the functionally dominant somatostatin receptor in human pancreatic β- and α-cells. Am J Physiol Endocrinol Metab. 2012 Nov 1;303(9):E1107-16. PMID: 22932785.

" Not dangerous goods.

LKT S5751 Somatostatin-25 0.5 mg 192.3 Endogenous neuropeptide hormone; somatostatin agonist, GABA modulator, P/Q-type, N-type, and L-type voltage-gated Ca2+ channel modulator. 76461-17-1 ≥95% 2876.36 C127H191N37O34S3 Ambient -20°C "Stumm R. Somatostatin receptor sst2 reduces Akt activity and aggravates hypoxic/ischemic death in cerebral cortical neurons. Neuropharmacology. 2014 Feb;77:249-56. PMID: 24157493.

 

Takahashi M, Takeda M, Matsumoto S. Somatostatin enhances tooth-pulp-evoked cervical dorsal horn neuronal activity in the rat via inhibition of GABAergic interneurons. Brain Res Bull. 2014 Jan;100:76-83. PMID: 24321530.

 

Albrecht A, Thiere M, Bergado-Acosta JR, et al. Circadian modulation of anxiety: a role for somatostatin in the amygdala. PLoS One. 2013 Dec 20;8(12):e84668. PMID: 24376834.

 

Kovac S, Walker MC. Neuropeptides in epilepsy. Neuropeptides. 2013 Dec;47(6):467-75. PMID: 24210141.

 

Begg DP, Woods SC. Interactions between the central nervous system and pancreatic islet secretions: a historical perspective. Adv Physiol Educ. 2013 Mar;37(1):53-60. PMID: 23471249.

 

Schwetz TA, Ustione A, Piston DW. Neuropeptide Y and somatostatin inhibit insulin secretion through different mechanisms. Am J Physiol Endocrinol Metab. 2013 Jan 15;304(2):E211-21. PMID: 23211512.

 

Kailey B, van de Bunt M, Cheley S, et al. SSTR2 is the functionally dominant somatostatin receptor in human pancreatic β- and α-cells. Am J Physiol Endocrinol Metab. 2012 Nov 1;303(9):E1107-16. PMID: 22932785.

" Not dangerous goods.

LKT S5751 Somatostatin-25 1 mg 327.1 Endogenous neuropeptide hormone; somatostatin agonist, GABA modulator, P/Q-type, N-type, and L-type voltage-gated Ca2+ channel modulator. 76461-17-1 ≥95% 2876.36 C127H191N37O34S3 Ambient -20°C "Stumm R. Somatostatin receptor sst2 reduces Akt activity and aggravates hypoxic/ischemic death in cerebral cortical neurons. Neuropharmacology. 2014 Feb;77:249-56. PMID: 24157493.

 

Takahashi M, Takeda M, Matsumoto S. Somatostatin enhances tooth-pulp-evoked cervical dorsal horn neuronal activity in the rat via inhibition of GABAergic interneurons. Brain Res Bull. 2014 Jan;100:76-83. PMID: 24321530.

 

Albrecht A, Thiere M, Bergado-Acosta JR, et al. Circadian modulation of anxiety: a role for somatostatin in the amygdala. PLoS One. 2013 Dec 20;8(12):e84668. PMID: 24376834.

 

Kovac S, Walker MC. Neuropeptides in epilepsy. Neuropeptides. 2013 Dec;47(6):467-75. PMID: 24210141.

 

Begg DP, Woods SC. Interactions between the central nervous system and pancreatic islet secretions: a historical perspective. Adv Physiol Educ. 2013 Mar;37(1):53-60. PMID: 23471249.

 

Schwetz TA, Ustione A, Piston DW. Neuropeptide Y and somatostatin inhibit insulin secretion through different mechanisms. Am J Physiol Endocrinol Metab. 2013 Jan 15;304(2):E211-21. PMID: 23211512.

 

Kailey B, van de Bunt M, Cheley S, et al. SSTR2 is the functionally dominant somatostatin receptor in human pancreatic β- and α-cells. Am J Physiol Endocrinol Metab. 2012 Nov 1;303(9):E1107-16. PMID: 22932785.

" Not dangerous goods.

LKT S5751 Somatostatin-25 2.5 mg 576.1 Endogenous neuropeptide hormone; somatostatin agonist, GABA modulator, P/Q-type, N-type, and L-type voltage-gated Ca2+ channel modulator. 76461-17-1 ≥95% 2876.36 C127H191N37O34S3 Ambient -20°C "Stumm R. Somatostatin receptor sst2 reduces Akt activity and aggravates hypoxic/ischemic death in cerebral cortical neurons. Neuropharmacology. 2014 Feb;77:249-56. PMID: 24157493.

 

Takahashi M, Takeda M, Matsumoto S. Somatostatin enhances tooth-pulp-evoked cervical dorsal horn neuronal activity in the rat via inhibition of GABAergic interneurons. Brain Res Bull. 2014 Jan;100:76-83. PMID: 24321530.

 

Albrecht A, Thiere M, Bergado-Acosta JR, et al. Circadian modulation of anxiety: a role for somatostatin in the amygdala. PLoS One. 2013 Dec 20;8(12):e84668. PMID: 24376834.

 

Kovac S, Walker MC. Neuropeptides in epilepsy. Neuropeptides. 2013 Dec;47(6):467-75. PMID: 24210141.

 

Begg DP, Woods SC. Interactions between the central nervous system and pancreatic islet secretions: a historical perspective. Adv Physiol Educ. 2013 Mar;37(1):53-60. PMID: 23471249.

 

Schwetz TA, Ustione A, Piston DW. Neuropeptide Y and somatostatin inhibit insulin secretion through different mechanisms. Am J Physiol Endocrinol Metab. 2013 Jan 15;304(2):E211-21. PMID: 23211512.

 

Kailey B, van de Bunt M, Cheley S, et al. SSTR2 is the functionally dominant somatostatin receptor in human pancreatic β- and α-cells. Am J Physiol Endocrinol Metab. 2012 Nov 1;303(9):E1107-16. PMID: 22932785.

" Not dangerous goods.

LKT S5750 Somatostatin-28 1 mg 781.4 Endogenous neuropeptide hormone; somatostatin agonist, GABA modulator, P/Q-type, N-type, and L-type voltage-gated Ca2+ channel modulator. Prosomatostatin 75037-27-3 ≥98% 3148.6 C137H207N41O39S3 CC(C1C(=O)NC(C(=O)NC(C(=O)NC(C(=O)NC(CSSCC(C(=O)NC(C(=O)NC(C(=O)NC(C(=O)NC(C(=O)NC(C(=O)NC(C(=O)N1)CCCCN)CC2=CNC3=CC=CC=C32)CC4=CC=CC=C4)CC5=CC=CC=C5)CC(=O)N)CCCCN)NC(=O)CNC(=O)C(C)NC(=O)C(CCCCN)NC(=O)C(CCCNC(=N)N)NC(=O)C(CCC(=O)O)NC(=O)C(CCCNC(=N)N)NC(=O)C6CCCN6C(=O)C(C)NC(=O)C(CCSC)NC(=O)C(C)NC(=O)C7CCCN7C(=O)C(CC(=O)N)NC(=O)C(CO)NC(=O)C(CC(=O)N)NC(=O)C(C)NC(=O)C(CO)N)C(=O)O)CO)C(C)O)CC8=CC=CC=C8)O Ambient -20°C Soluble in water. "Stumm R. Somatostatin receptor sst2 reduces Akt activity and aggravates hypoxic/ischemic death in cerebral cortical neurons. Neuropharmacology. 2014 Feb;77:249-56. PMID: 24157493.

 

Takahashi M, Takeda M, Matsumoto S. Somatostatin enhances tooth-pulp-evoked cervical dorsal horn neuronal activity in the rat via inhibition of GABAergic interneurons. Brain Res Bull. 2014 Jan;100:76-83. PMID: 24321530.

 

Albrecht A, Thiere M, Bergado-Acosta JR, et al. Circadian modulation of anxiety: a role for somatostatin in the amygdala. PLoS One. 2013 Dec 20;8(12):e84668. PMID: 24376834.

 

Kovac S, Walker MC. Neuropeptides in epilepsy. Neuropeptides. 2013 Dec;47(6):467-75. PMID: 24210141.

 

Begg DP, Woods SC. Interactions between the central nervous system and pancreatic islet secretions: a historical perspective. Adv Physiol Educ. 2013 Mar;37(1):53-60. PMID: 23471249.

 

Schwetz TA, Ustione A, Piston DW. Neuropeptide Y and somatostatin inhibit insulin secretion through different mechanisms. Am J Physiol Endocrinol Metab. 2013 Jan 15;304(2):E211-21. PMID: 23211512.

 

Kailey B, van de Bunt M, Cheley S, et al. SSTR2 is the functionally dominant somatostatin receptor in human pancreatic β- and α-cells. Am J Physiol Endocrinol Metab. 2012 Nov 1;303(9):E1107-16. PMID: 22932785.

" Not dangerous goods.

LKT S5749 Somatostatin-14 5 mg 144 Endogenous neuropeptide hormone; somatostatin agonist, GABA modulator, P/Q-type, N-type, and L-type voltage-gated Ca2+ channel modulator. Somatostatin; Growth hormone release-inhibiting factor; Somatotropin release-inhibiting hormone 51110-01-1 ≥95% 1637.92 C76H104N18O19S2 CC(C1C(=O)NC(C(=O)NC(C(=O)NC(C(=O)NC(CSSCC(C(=O)NC(C(=O)NC(C(=O)NC(C(=O)NC(C(=O)NC(C(=O)NC(C(=O)N1)CCCCN)CC2=CNC3=CC=CC=C32)CC4=CC=CC=C4)CC5=CC=CC=C5)CC(=O)N)CCCCN)NC(=O)CNC(=O)C(C)N)C(=O)O)CO)C(C)O)CC6=CC=CC=C6)O Ambient -20°C Soluble in 5% acetic acid. "Stumm R. Somatostatin receptor sst2 reduces Akt activity and aggravates hypoxic/ischemic death in cerebral cortical neurons. Neuropharmacology. 2014 Feb;77:249-56. PMID: 24157493.

 

Takahashi M, Takeda M, Matsumoto S. Somatostatin enhances tooth-pulp-evoked cervical dorsal horn neuronal activity in the rat via inhibition of GABAergic interneurons. Brain Res Bull. 2014 Jan;100:76-83. PMID: 24321530.

 

Albrecht A, Thiere M, Bergado-Acosta JR, et al. Circadian modulation of anxiety: a role for somatostatin in the amygdala. PLoS One. 2013 Dec 20;8(12):e84668. PMID: 24376834.

 

Kovac S, Walker MC. Neuropeptides in epilepsy. Neuropeptides. 2013 Dec;47(6):467-75. PMID: 24210141.

 

Begg DP, Woods SC. Interactions between the central nervous system and pancreatic islet secretions: a historical perspective. Adv Physiol Educ. 2013 Mar;37(1):53-60. PMID: 23471249.

 

Schwetz TA, Ustione A, Piston DW. Neuropeptide Y and somatostatin inhibit insulin secretion through different mechanisms. Am J Physiol Endocrinol Metab. 2013 Jan 15;304(2):E211-21. PMID: 23211512.

 

Kailey B, van de Bunt M, Cheley S, et al. SSTR2 is the functionally dominant somatostatin receptor in human pancreatic β- and α-cells. Am J Physiol Endocrinol Metab. 2012 Nov 1;303(9):E1107-16. PMID: 22932785.

" Xn Not dangerous goods.

LKT S5749 Somatostatin-14 10 mg 245.9 Endogenous neuropeptide hormone; somatostatin agonist, GABA modulator, P/Q-type, N-type, and L-type voltage-gated Ca2+ channel modulator. Somatostatin; Growth hormone release-inhibiting factor; Somatotropin release-inhibiting hormone 51110-01-1 ≥95% 1637.92 C76H104N18O19S2 CC(C1C(=O)NC(C(=O)NC(C(=O)NC(C(=O)NC(CSSCC(C(=O)NC(C(=O)NC(C(=O)NC(C(=O)NC(C(=O)NC(C(=O)NC(C(=O)N1)CCCCN)CC2=CNC3=CC=CC=C32)CC4=CC=CC=C4)CC5=CC=CC=C5)CC(=O)N)CCCCN)NC(=O)CNC(=O)C(C)N)C(=O)O)CO)C(C)O)CC6=CC=CC=C6)O Ambient -20°C Soluble in 5% acetic acid. "Stumm R. Somatostatin receptor sst2 reduces Akt activity and aggravates hypoxic/ischemic death in cerebral cortical neurons. Neuropharmacology. 2014 Feb;77:249-56. PMID: 24157493.

 

Takahashi M, Takeda M, Matsumoto S. Somatostatin enhances tooth-pulp-evoked cervical dorsal horn neuronal activity in the rat via inhibition of GABAergic interneurons. Brain Res Bull. 2014 Jan;100:76-83. PMID: 24321530.

 

Albrecht A, Thiere M, Bergado-Acosta JR, et al. Circadian modulation of anxiety: a role for somatostatin in the amygdala. PLoS One. 2013 Dec 20;8(12):e84668. PMID: 24376834.

 

Kovac S, Walker MC. Neuropeptides in epilepsy. Neuropeptides. 2013 Dec;47(6):467-75. PMID: 24210141.

 

Begg DP, Woods SC. Interactions between the central nervous system and pancreatic islet secretions: a historical perspective. Adv Physiol Educ. 2013 Mar;37(1):53-60. PMID: 23471249.

 

Schwetz TA, Ustione A, Piston DW. Neuropeptide Y and somatostatin inhibit insulin secretion through different mechanisms. Am J Physiol Endocrinol Metab. 2013 Jan 15;304(2):E211-21. PMID: 23211512.

 

Kailey B, van de Bunt M, Cheley S, et al. SSTR2 is the functionally dominant somatostatin receptor in human pancreatic β- and α-cells. Am J Physiol Endocrinol Metab. 2012 Nov 1;303(9):E1107-16. PMID: 22932785.

" Xn Not dangerous goods.

LKT S5749 Somatostatin-14 25 mg 432 Endogenous neuropeptide hormone; somatostatin agonist, GABA modulator, P/Q-type, N-type, and L-type voltage-gated Ca2+ channel modulator. Somatostatin; Growth hormone release-inhibiting factor; Somatotropin release-inhibiting hormone 51110-01-1 ≥95% 1637.92 C76H104N18O19S2 CC(C1C(=O)NC(C(=O)NC(C(=O)NC(C(=O)NC(CSSCC(C(=O)NC(C(=O)NC(C(=O)NC(C(=O)NC(C(=O)NC(C(=O)NC(C(=O)N1)CCCCN)CC2=CNC3=CC=CC=C32)CC4=CC=CC=C4)CC5=CC=CC=C5)CC(=O)N)CCCCN)NC(=O)CNC(=O)C(C)N)C(=O)O)CO)C(C)O)CC6=CC=CC=C6)O Ambient -20°C Soluble in 5% acetic acid. "Stumm R. Somatostatin receptor sst2 reduces Akt activity and aggravates hypoxic/ischemic death in cerebral cortical neurons. Neuropharmacology. 2014 Feb;77:249-56. PMID: 24157493.

 

Takahashi M, Takeda M, Matsumoto S. Somatostatin enhances tooth-pulp-evoked cervical dorsal horn neuronal activity in the rat via inhibition of GABAergic interneurons. Brain Res Bull. 2014 Jan;100:76-83. PMID: 24321530.

 

Albrecht A, Thiere M, Bergado-Acosta JR, et al. Circadian modulation of anxiety: a role for somatostatin in the amygdala. PLoS One. 2013 Dec 20;8(12):e84668. PMID: 24376834.

 

Kovac S, Walker MC. Neuropeptides in epilepsy. Neuropeptides. 2013 Dec;47(6):467-75. PMID: 24210141.

 

Begg DP, Woods SC. Interactions between the central nervous system and pancreatic islet secretions: a historical perspective. Adv Physiol Educ. 2013 Mar;37(1):53-60. PMID: 23471249.

 

Schwetz TA, Ustione A, Piston DW. Neuropeptide Y and somatostatin inhibit insulin secretion through different mechanisms. Am J Physiol Endocrinol Metab. 2013 Jan 15;304(2):E211-21. PMID: 23211512.

 

Kailey B, van de Bunt M, Cheley S, et al. SSTR2 is the functionally dominant somatostatin receptor in human pancreatic β- and α-cells. Am J Physiol Endocrinol Metab. 2012 Nov 1;303(9):E1107-16. PMID: 22932785.

" Xn Not dangerous goods.

LKT M1708 Mecamylamine Hydrochloride 5 mg 51.7 Monoterpene; nAChR antagonist. "inversine, 2-(methylamino)isocamphane

hydrochloride, N,2,3,3-tetramethyl-2-norbornanamine,

N,2,3,3-tetramethylbicyclo[2.2.1]heptan-2-amine

hydrochloride" 826-39-1 ≥98% 203.75 C11H21N HCl CC1(C2CCC(C2)C1(C)NC)C.Cl Ambient Ambient "Peng C, Kimbrell MR, Tian C, et al. Multiple modes of α7 nAChR noncompetitive antagonism of control agonist-evoked and allosterically enhanced currents. Mol Pharmacol. 2013 Sep;84(3):459-75. PMID: 23839567.

 

Sanberg PR, Vindrola-Padros C, Shytle RD. Translating laboratory discovery to the clinic: from nicotine and mecamylamine to Tourette's, depression, and beyond. Physiol Behav. 2012 Dec 5;107(5):801-8. PMID: 22776623.

 

LeSage MG, Shelley D, Pravetoni M, et al. Enhanced attenuation of nicotine discrimination in rats by combining nicotine-specific antibodies with a nicotinic receptor antagonist. Pharmacol Biochem Behav. 2012 Jul;102(1):157-62. PMID: 22503967.

 

Bacher I, Wu B, Shytle DR, et al. Mecamylamine - a nicotinic acetylcholine receptor antagonist with potential for the treatment of neuropsychiatric disorders. Expert Opin Pharmacother. 2009 Nov;10(16):2709-21. PMID: 19874251.

 

Lippiello PM, Beaver JS, Gatto GJ, et al. TC-5214 (S-(+)-mecamylamine): a neuronal nicotinic receptor modulator with antidepressant activity. CNS Neurosci Ther. 2008 Winter;14(4):266-77. PMID: 19040552.

 

Shytle RD, Penny E, Silver AA, et al. Mecamylamine (Inversine): an old antihypertensive with new research directions. J Hum Hypertens. 2002 Jul;16(7):453-7. PMID: 12080428.

 

Hayashi E, Yamada S, Mori M. Comparative studies on anti-nicotinic action of hexamethonium, mecamylamine and adenosine in the guinea pig isolated ileum. Jpn J Pharmacol. 1977 Oct;27(5):659-65. PMID: 592556.

" Xn "UN number: 2811     Class: 6.1     Packing Group: III

Proper shipping name: Toxic solid, organic, n.o.s. (Mecamylamine hydrochloride)"

LKT M1708 Mecamylamine Hydrochloride 25 mg 187.4 Monoterpene; nAChR antagonist. "inversine, 2-(methylamino)isocamphane

hydrochloride, N,2,3,3-tetramethyl-2-norbornanamine,

N,2,3,3-tetramethylbicyclo[2.2.1]heptan-2-amine

hydrochloride" 826-39-1 ≥98% 203.75 C11H21N HCl CC1(C2CCC(C2)C1(C)NC)C.Cl Ambient Ambient "Peng C, Kimbrell MR, Tian C, et al. Multiple modes of α7 nAChR noncompetitive antagonism of control agonist-evoked and allosterically enhanced currents. Mol Pharmacol. 2013 Sep;84(3):459-75. PMID: 23839567.

 

Sanberg PR, Vindrola-Padros C, Shytle RD. Translating laboratory discovery to the clinic: from nicotine and mecamylamine to Tourette's, depression, and beyond. Physiol Behav. 2012 Dec 5;107(5):801-8. PMID: 22776623.

 

LeSage MG, Shelley D, Pravetoni M, et al. Enhanced attenuation of nicotine discrimination in rats by combining nicotine-specific antibodies with a nicotinic receptor antagonist. Pharmacol Biochem Behav. 2012 Jul;102(1):157-62. PMID: 22503967.

 

Bacher I, Wu B, Shytle DR, et al. Mecamylamine - a nicotinic acetylcholine receptor antagonist with potential for the treatment of neuropsychiatric disorders. Expert Opin Pharmacother. 2009 Nov;10(16):2709-21. PMID: 19874251.

 

Lippiello PM, Beaver JS, Gatto GJ, et al. TC-5214 (S-(+)-mecamylamine): a neuronal nicotinic receptor modulator with antidepressant activity. CNS Neurosci Ther. 2008 Winter;14(4):266-77. PMID: 19040552.

 

Shytle RD, Penny E, Silver AA, et al. Mecamylamine (Inversine): an old antihypertensive with new research directions. J Hum Hypertens. 2002 Jul;16(7):453-7. PMID: 12080428.

 

Hayashi E, Yamada S, Mori M. Comparative studies on anti-nicotinic action of hexamethonium, mecamylamine and adenosine in the guinea pig isolated ileum. Jpn J Pharmacol. 1977 Oct;27(5):659-65. PMID: 592556.

" Xn "UN number: 2811     Class: 6.1     Packing Group: III

Proper shipping name: Toxic solid, organic, n.o.s. (Mecamylamine hydrochloride)"

LKT M1708 Mecamylamine Hydrochloride 100 mg 600.1 Monoterpene; nAChR antagonist. "inversine, 2-(methylamino)isocamphane

hydrochloride, N,2,3,3-tetramethyl-2-norbornanamine,

N,2,3,3-tetramethylbicyclo[2.2.1]heptan-2-amine

hydrochloride" 826-39-1 ≥98% 203.75 C11H21N HCl CC1(C2CCC(C2)C1(C)NC)C.Cl Ambient Ambient "Peng C, Kimbrell MR, Tian C, et al. Multiple modes of α7 nAChR noncompetitive antagonism of control agonist-evoked and allosterically enhanced currents. Mol Pharmacol. 2013 Sep;84(3):459-75. PMID: 23839567.

 

Sanberg PR, Vindrola-Padros C, Shytle RD. Translating laboratory discovery to the clinic: from nicotine and mecamylamine to Tourette's, depression, and beyond. Physiol Behav. 2012 Dec 5;107(5):801-8. PMID: 22776623.

 

LeSage MG, Shelley D, Pravetoni M, et al. Enhanced attenuation of nicotine discrimination in rats by combining nicotine-specific antibodies with a nicotinic receptor antagonist. Pharmacol Biochem Behav. 2012 Jul;102(1):157-62. PMID: 22503967.

 

Bacher I, Wu B, Shytle DR, et al. Mecamylamine - a nicotinic acetylcholine receptor antagonist with potential for the treatment of neuropsychiatric disorders. Expert Opin Pharmacother. 2009 Nov;10(16):2709-21. PMID: 19874251.

 

Lippiello PM, Beaver JS, Gatto GJ, et al. TC-5214 (S-(+)-mecamylamine): a neuronal nicotinic receptor modulator with antidepressant activity. CNS Neurosci Ther. 2008 Winter;14(4):266-77. PMID: 19040552.

 

Shytle RD, Penny E, Silver AA, et al. Mecamylamine (Inversine): an old antihypertensive with new research directions. J Hum Hypertens. 2002 Jul;16(7):453-7. PMID: 12080428.

 

Hayashi E, Yamada S, Mori M. Comparative studies on anti-nicotinic action of hexamethonium, mecamylamine and adenosine in the guinea pig isolated ileum. Jpn J Pharmacol. 1977 Oct;27(5):659-65. PMID: 592556.

" Xn "UN number: 2811     Class: 6.1     Packing Group: III

Proper shipping name: Toxic solid, organic, n.o.s. (Mecamylamine hydrochloride)"

LKT M1744 Melittin 0.5 mg 228 Antimicrobial peptide found in Apis mellifera. Mellitin; Melitten I, Forapin 20449-79-0 ≥98% 2846.5 C131H229N39O31 CCC(C)C(C(=O)NCC(=O)NC(C)C(=O)NC(C(C)C)C(=O)NC(CC(C)C)C(=O)NC(CCCCN)C(=O)NC(C(C)C)C(=O)NC(CC(C)C)C(=O)NC(C(C)O)C(=O)NC(C(C)O)C(=O)NCC(=O)NC(CC(C)C)C(=O)N1CCCC1C(=O)NC(C)C(=O)NC(CC(C)C)C(=O)NC(C(C)CC)C(=O)NC(CO)C(=O)NC(CC2=CNC3=CC=CC=C32)C(=O)NC(C(C)CC)C(=O)NC(CCCCN)C(=O)NC(CCCNC(=N)N)C(=O)NC(CCCCN)C(=O)NC(CCCNC(=N)N)C(=O)NC(CCC(=O)N)C(=O)NC(CCC(=O)N)C(=O)N)NC(=O)CN Ambient -20°C Soluble in water (5mg/mL) or PBS (5mg/mL). "Lee J, Lee DG. Melittin triggers apoptosis in Candida albicans through the reactive oxygen species-mediated mitochondria/caspase-dependent pathway. FEMS Microbiol Lett. 2014 Apr 27. [Epub ahead of print]. PMID: 24766524.

 

Lee MT, Sun TL, Hung WC, et al. Process of inducing pores in membranes by melittin. Proc Natl Acad Sci U S A. 2013 Aug 27;110(35):14243-8. PMID: 23940362.

 

Adade CM, Oliveira IR, Pais JA, et al. Melittin peptide kills Trypanosoma cruzi parasites by inducing different cell death pathways. Toxicon. 2013 Jul;69:227-39. PMID: 23562368.

" T "UN number: 2811     Class: 6.1      Packing Group: III

Proper shipping name: Toxic solid, organic. n.o.s. (Melittin)"

LKT M1744 Melittin 1 mg 387 Antimicrobial peptide found in Apis mellifera. Mellitin; Melitten I, Forapin 20449-79-0 ≥98% 2846.5 C131H229N39O31 CCC(C)C(C(=O)NCC(=O)NC(C)C(=O)NC(C(C)C)C(=O)NC(CC(C)C)C(=O)NC(CCCCN)C(=O)NC(C(C)C)C(=O)NC(CC(C)C)C(=O)NC(C(C)O)C(=O)NC(C(C)O)C(=O)NCC(=O)NC(CC(C)C)C(=O)N1CCCC1C(=O)NC(C)C(=O)NC(CC(C)C)C(=O)NC(C(C)CC)C(=O)NC(CO)C(=O)NC(CC2=CNC3=CC=CC=C32)C(=O)NC(C(C)CC)C(=O)NC(CCCCN)C(=O)NC(CCCNC(=N)N)C(=O)NC(CCCCN)C(=O)NC(CCCNC(=N)N)C(=O)NC(CCC(=O)N)C(=O)NC(CCC(=O)N)C(=O)N)NC(=O)CN Ambient -20°C Soluble in water (5mg/mL) or PBS (5mg/mL). "Lee J, Lee DG. Melittin triggers apoptosis in Candida albicans through the reactive oxygen species-mediated mitochondria/caspase-dependent pathway. FEMS Microbiol Lett. 2014 Apr 27. [Epub ahead of print]. PMID: 24766524.

 

Lee MT, Sun TL, Hung WC, et al. Process of inducing pores in membranes by melittin. Proc Natl Acad Sci U S A. 2013 Aug 27;110(35):14243-8. PMID: 23940362.

 

Adade CM, Oliveira IR, Pais JA, et al. Melittin peptide kills Trypanosoma cruzi parasites by inducing different cell death pathways. Toxicon. 2013 Jul;69:227-39. PMID: 23562368.

" T "UN number: 2811     Class: 6.1      Packing Group: III

Proper shipping name: Toxic solid, organic. n.o.s. (Melittin)"

LKT M1744 Melittin 2.5 mg 684.1 Antimicrobial peptide found in Apis mellifera. Mellitin; Melitten I, Forapin 20449-79-0 ≥98% 2846.5 C131H229N39O31 CCC(C)C(C(=O)NCC(=O)NC(C)C(=O)NC(C(C)C)C(=O)NC(CC(C)C)C(=O)NC(CCCCN)C(=O)NC(C(C)C)C(=O)NC(CC(C)C)C(=O)NC(C(C)O)C(=O)NC(C(C)O)C(=O)NCC(=O)NC(CC(C)C)C(=O)N1CCCC1C(=O)NC(C)C(=O)NC(CC(C)C)C(=O)NC(C(C)CC)C(=O)NC(CO)C(=O)NC(CC2=CNC3=CC=CC=C32)C(=O)NC(C(C)CC)C(=O)NC(CCCCN)C(=O)NC(CCCNC(=N)N)C(=O)NC(CCCCN)C(=O)NC(CCCNC(=N)N)C(=O)NC(CCC(=O)N)C(=O)NC(CCC(=O)N)C(=O)N)NC(=O)CN Ambient -20°C Soluble in water (5mg/mL) or PBS (5mg/mL). "Lee J, Lee DG. Melittin triggers apoptosis in Candida albicans through the reactive oxygen species-mediated mitochondria/caspase-dependent pathway. FEMS Microbiol Lett. 2014 Apr 27. [Epub ahead of print]. PMID: 24766524.

 

Lee MT, Sun TL, Hung WC, et al. Process of inducing pores in membranes by melittin. Proc Natl Acad Sci U S A. 2013 Aug 27;110(35):14243-8. PMID: 23940362.

 

Adade CM, Oliveira IR, Pais JA, et al. Melittin peptide kills Trypanosoma cruzi parasites by inducing different cell death pathways. Toxicon. 2013 Jul;69:227-39. PMID: 23562368.

" T "UN number: 2811     Class: 6.1      Packing Group: III

Proper shipping name: Toxic solid, organic. n.o.s. (Melittin)"

LKT M1745 Melatonin 1 g 59.9 Endogenous hormone involved in circadian rhythms; MT agonist. N-[2-(5-Methoxy-1H-indol-3-yl)ethyl]acetamide Regulin; N-Acetyl-5-methoxytryptamine 73-31-4 ≥98% 232.27 C13H16N2O2 CC(=O)NCCC1=CNC2=C1C=C(C=C2)OC Ambient 4°C Soluble in DMSO.  Insoluble in water. "Kandil TS, Mousa AA, El-Gendy AA, et al. The potential therapeutic effect of melatonin in Gastro-Esophageal Reflux Disease. BMC Gastroenterol. 2010 Jan 18;10:7. PMID: 20082715.

 

Anisimov VN, Popovich IG, Zabezhinski MA, et al. Melatonin as antioxidant, geroprotector and anticarcinogen. Biochim Biophys Acta. 2006 May-Jun;1757(5-6):573-89. PMID: 16678784.

 

Mills E, Wu P, Seely D, et al. Melatonin in the treatment of cancer: a systematic review of randomized controlled trials and meta-analysis. J Pineal Res. 2005 Nov;39(4):360-6. PMID: 16207291.

 

Hardeland R. Antioxidative protection by melatonin: multiplicity of mechanisms from radical detoxification to radical avoidance. Endocrine. 2005 Jul;27(2):119-30. PMID: 16217125.

 

Wang XC, Zhang J, Yu X, et al. Prevention of isoproterenol-induced tau hyperphosphorylation by melatonin in the rat. Sheng Li Xue Bao. 2005 Feb 25;57(1):7-12. PMID: 15719129.

 

Gagnier JJ. The therapeutic potential of melatonin in migraines and other headache types. Altern Med Rev. 2001 Aug;6(4):383-9. PMID: 11578254.

 

Maestroni GJ. The immunotherapeutic potential of melatonin. Expert Opin Investig Drugs. 2001 Mar;10(3):467-76. PMID: 11227046.

 

Wolden-Hanson T, Mitton DR, McCants RL, et al. Daily melatonin administration to middle-aged male rats suppresses body weight, intraabdominal adiposity, and plasma leptin and insulin independent of food intake and total body fat. Endocrinology. 2000 Feb;141(2):487-97. PMID: 10650927.

 

Pappolla M, Bozner P, Soto C, et al. Inhibition of Alzheimer beta-fibrillogenesis by melatonin. J Biol Chem. 1998 Mar 27;273(13):7185-8. PMID: 9516407.

" Repr. Not dangerous goods.

LKT M1745 Melatonin 5 g 293.6 Endogenous hormone involved in circadian rhythms; MT agonist. N-[2-(5-Methoxy-1H-indol-3-yl)ethyl]acetamide Regulin; N-Acetyl-5-methoxytryptamine 73-31-4 ≥98% 232.27 C13H16N2O2 CC(=O)NCCC1=CNC2=C1C=C(C=C2)OC Ambient 4°C Soluble in DMSO.  Insoluble in water. "Kandil TS, Mousa AA, El-Gendy AA, et al. The potential therapeutic effect of melatonin in Gastro-Esophageal Reflux Disease. BMC Gastroenterol. 2010 Jan 18;10:7. PMID: 20082715.

 

Anisimov VN, Popovich IG, Zabezhinski MA, et al. Melatonin as antioxidant, geroprotector and anticarcinogen. Biochim Biophys Acta. 2006 May-Jun;1757(5-6):573-89. PMID: 16678784.

 

Mills E, Wu P, Seely D, et al. Melatonin in the treatment of cancer: a systematic review of randomized controlled trials and meta-analysis. J Pineal Res. 2005 Nov;39(4):360-6. PMID: 16207291.

 

Hardeland R. Antioxidative protection by melatonin: multiplicity of mechanisms from radical detoxification to radical avoidance. Endocrine. 2005 Jul;27(2):119-30. PMID: 16217125.

 

Wang XC, Zhang J, Yu X, et al. Prevention of isoproterenol-induced tau hyperphosphorylation by melatonin in the rat. Sheng Li Xue Bao. 2005 Feb 25;57(1):7-12. PMID: 15719129.

 

Gagnier JJ. The therapeutic potential of melatonin in migraines and other headache types. Altern Med Rev. 2001 Aug;6(4):383-9. PMID: 11578254.

 

Maestroni GJ. The immunotherapeutic potential of melatonin. Expert Opin Investig Drugs. 2001 Mar;10(3):467-76. PMID: 11227046.

 

Wolden-Hanson T, Mitton DR, McCants RL, et al. Daily melatonin administration to middle-aged male rats suppresses body weight, intraabdominal adiposity, and plasma leptin and insulin independent of food intake and total body fat. Endocrinology. 2000 Feb;141(2):487-97. PMID: 10650927.

 

Pappolla M, Bozner P, Soto C, et al. Inhibition of Alzheimer beta-fibrillogenesis by melatonin. J Biol Chem. 1998 Mar 27;273(13):7185-8. PMID: 9516407.

" Repr. Not dangerous goods.

LKT M1745 Melatonin 10 g 503.3 Endogenous hormone involved in circadian rhythms; MT agonist. N-[2-(5-Methoxy-1H-indol-3-yl)ethyl]acetamide Regulin; N-Acetyl-5-methoxytryptamine 73-31-4 ≥98% 232.27 C13H16N2O2 CC(=O)NCCC1=CNC2=C1C=C(C=C2)OC Ambient 4°C Soluble in DMSO.  Insoluble in water. "Kandil TS, Mousa AA, El-Gendy AA, et al. The potential therapeutic effect of melatonin in Gastro-Esophageal Reflux Disease. BMC Gastroenterol. 2010 Jan 18;10:7. PMID: 20082715.

 

Anisimov VN, Popovich IG, Zabezhinski MA, et al. Melatonin as antioxidant, geroprotector and anticarcinogen. Biochim Biophys Acta. 2006 May-Jun;1757(5-6):573-89. PMID: 16678784.

 

Mills E, Wu P, Seely D, et al. Melatonin in the treatment of cancer: a systematic review of randomized controlled trials and meta-analysis. J Pineal Res. 2005 Nov;39(4):360-6. PMID: 16207291.

 

Hardeland R. Antioxidative protection by melatonin: multiplicity of mechanisms from radical detoxification to radical avoidance. Endocrine. 2005 Jul;27(2):119-30. PMID: 16217125.

 

Wang XC, Zhang J, Yu X, et al. Prevention of isoproterenol-induced tau hyperphosphorylation by melatonin in the rat. Sheng Li Xue Bao. 2005 Feb 25;57(1):7-12. PMID: 15719129.

 

Gagnier JJ. The therapeutic potential of melatonin in migraines and other headache types. Altern Med Rev. 2001 Aug;6(4):383-9. PMID: 11578254.

 

Maestroni GJ. The immunotherapeutic potential of melatonin. Expert Opin Investig Drugs. 2001 Mar;10(3):467-76. PMID: 11227046.

 

Wolden-Hanson T, Mitton DR, McCants RL, et al. Daily melatonin administration to middle-aged male rats suppresses body weight, intraabdominal adiposity, and plasma leptin and insulin independent of food intake and total body fat. Endocrinology. 2000 Feb;141(2):487-97. PMID: 10650927.

 

Pappolla M, Bozner P, Soto C, et al. Inhibition of Alzheimer beta-fibrillogenesis by melatonin. J Biol Chem. 1998 Mar 27;273(13):7185-8. PMID: 9516407.

" Repr. Not dangerous goods.

LKT M1746 Melphalan 100 mg 133.9 Nitrogen mustard, DNA alkylator. 4-[Bis(2-chloroethyl)amino]-L-phenylalanine L-PAM; L-Phenylalanine mustard; L-Sarcolysine; Alkeran; Sarcoclorin 148-82-3 ≥94% 305.2 C13H18Cl2N2O2 C1=CC(=CC=C1CC(C(=O)O)N)N(CCCl)CCCl Ambient 4°C Soluble in ethanol or propylene glycol. Practically insoluble in water. "Polavarapu A, Stillabower JA, Stubblefield SG, et al. The mechanism of guanine alkylation by nitrogen mustards: a computational study.

 J Org Chem. 2012 Jul 20;77(14):5914-21. PMID: 22681226.

 

Falco P, Bringhen S, Avonto I, et al. Melphalan and its role in the management of patients with multiple myeloma.

 Expert Rev Anticancer Ther. 2007 Jul;7(7):945-57. PMID: 17627453.

" T+ "UN number: 2811     Class: 6.1     Packing Group: II

Proper shipping name: Toxic solid, organic, n.o.s. (Melphalan)"

LKT M1746 Melphalan 250 mg 251.3 Nitrogen mustard, DNA alkylator. 4-[Bis(2-chloroethyl)amino]-L-phenylalanine L-PAM; L-Phenylalanine mustard; L-Sarcolysine; Alkeran; Sarcoclorin 148-82-3 ≥94% 305.2 C13H18Cl2N2O2 C1=CC(=CC=C1CC(C(=O)O)N)N(CCCl)CCCl Ambient 4°C Soluble in ethanol or propylene glycol. Practically insoluble in water. "Polavarapu A, Stillabower JA, Stubblefield SG, et al. The mechanism of guanine alkylation by nitrogen mustards: a computational study.

 J Org Chem. 2012 Jul 20;77(14):5914-21. PMID: 22681226.

 

Falco P, Bringhen S, Avonto I, et al. Melphalan and its role in the management of patients with multiple myeloma.

 Expert Rev Anticancer Ther. 2007 Jul;7(7):945-57. PMID: 17627453.

" T+ "UN number: 2811     Class: 6.1     Packing Group: II

Proper shipping name: Toxic solid, organic, n.o.s. (Melphalan)"

LKT M1746 Melphalan 1 g 669.7 Nitrogen mustard, DNA alkylator. 4-[Bis(2-chloroethyl)amino]-L-phenylalanine L-PAM; L-Phenylalanine mustard; L-Sarcolysine; Alkeran; Sarcoclorin 148-82-3 ≥94% 305.2 C13H18Cl2N2O2 C1=CC(=CC=C1CC(C(=O)O)N)N(CCCl)CCCl Ambient 4°C Soluble in ethanol or propylene glycol. Practically insoluble in water. "Polavarapu A, Stillabower JA, Stubblefield SG, et al. The mechanism of guanine alkylation by nitrogen mustards: a computational study.

 J Org Chem. 2012 Jul 20;77(14):5914-21. PMID: 22681226.

 

Falco P, Bringhen S, Avonto I, et al. Melphalan and its role in the management of patients with multiple myeloma.

 Expert Rev Anticancer Ther. 2007 Jul;7(7):945-57. PMID: 17627453.

" T+ "UN number: 2811     Class: 6.1     Packing Group: II

Proper shipping name: Toxic solid, organic, n.o.s. (Melphalan)"

LKT S5747 [Tyr11]-Somatostatin 1 mg 107.8 Endogenous neuropeptide hormone; somatostatin agonist, GABA modulator, P/Q-type, N-type, and L-type voltage-gated Ca2+ channel modulator. 59481-27-5 ≥95% 1651.91 C76H102N18O20S2 CC(C1C(=O)NC(C(=O)NC(C(=O)NC(C(=O)NC(CSSCC(C(=O)NC(C(=O)NC(C(=O)NC(C(=O)NC(C(=O)NC(C(=O)NC(C(=O)N1)CCCCN)CC2=CC3=CC=CC=C3N2)CC4=CC=CC=C4)CC5=CC=CC=C5)CC(=O)N)CCCCN)NC(=O)CNC(=O)C(C)N)C(=O)O)CO)C(C)O)CC6=CC=C(C=C6)O)O Ambient -20°C "Stumm R. Somatostatin receptor sst2 reduces Akt activity and aggravates hypoxic/ischemic death in cerebral cortical neurons. Neuropharmacology. 2014 Feb;77:249-56. PMID: 24157493.

 

Takahashi M, Takeda M, Matsumoto S. Somatostatin enhances tooth-pulp-evoked cervical dorsal horn neuronal activity in the rat via inhibition of GABAergic interneurons. Brain Res Bull. 2014 Jan;100:76-83. PMID: 24321530.

 

Albrecht A, Thiere M, Bergado-Acosta JR, et al. Circadian modulation of anxiety: a role for somatostatin in the amygdala. PLoS One. 2013 Dec 20;8(12):e84668. PMID: 24376834.

 

Kovac S, Walker MC. Neuropeptides in epilepsy. Neuropeptides. 2013 Dec;47(6):467-75. PMID: 24210141.

 

Begg DP, Woods SC. Interactions between the central nervous system and pancreatic islet secretions: a historical perspective. Adv Physiol Educ. 2013 Mar;37(1):53-60. PMID: 23471249.

 

Schwetz TA, Ustione A, Piston DW. Neuropeptide Y and somatostatin inhibit insulin secretion through different mechanisms. Am J Physiol Endocrinol Metab. 2013 Jan 15;304(2):E211-21. PMID: 23211512.

 

Kailey B, van de Bunt M, Cheley S, et al. SSTR2 is the functionally dominant somatostatin receptor in human pancreatic β- and α-cells. Am J Physiol Endocrinol Metab. 2012 Nov 1;303(9):E1107-16. PMID: 22932785.

"

LKT S5747 [Tyr11]-Somatostatin 2 mg 183 Endogenous neuropeptide hormone; somatostatin agonist, GABA modulator, P/Q-type, N-type, and L-type voltage-gated Ca2+ channel modulator. 59481-27-5 ≥95% 1651.91 C76H102N18O20S2 CC(C1C(=O)NC(C(=O)NC(C(=O)NC(C(=O)NC(CSSCC(C(=O)NC(C(=O)NC(C(=O)NC(C(=O)NC(C(=O)NC(C(=O)NC(C(=O)N1)CCCCN)CC2=CC3=CC=CC=C3N2)CC4=CC=CC=C4)CC5=CC=CC=C5)CC(=O)N)CCCCN)NC(=O)CNC(=O)C(C)N)C(=O)O)CO)C(C)O)CC6=CC=C(C=C6)O)O Ambient -20°C "Stumm R. Somatostatin receptor sst2 reduces Akt activity and aggravates hypoxic/ischemic death in cerebral cortical neurons. Neuropharmacology. 2014 Feb;77:249-56. PMID: 24157493.

 

Takahashi M, Takeda M, Matsumoto S. Somatostatin enhances tooth-pulp-evoked cervical dorsal horn neuronal activity in the rat via inhibition of GABAergic interneurons. Brain Res Bull. 2014 Jan;100:76-83. PMID: 24321530.

 

Albrecht A, Thiere M, Bergado-Acosta JR, et al. Circadian modulation of anxiety: a role for somatostatin in the amygdala. PLoS One. 2013 Dec 20;8(12):e84668. PMID: 24376834.

 

Kovac S, Walker MC. Neuropeptides in epilepsy. Neuropeptides. 2013 Dec;47(6):467-75. PMID: 24210141.

 

Begg DP, Woods SC. Interactions between the central nervous system and pancreatic islet secretions: a historical perspective. Adv Physiol Educ. 2013 Mar;37(1):53-60. PMID: 23471249.

 

Schwetz TA, Ustione A, Piston DW. Neuropeptide Y and somatostatin inhibit insulin secretion through different mechanisms. Am J Physiol Endocrinol Metab. 2013 Jan 15;304(2):E211-21. PMID: 23211512.

 

Kailey B, van de Bunt M, Cheley S, et al. SSTR2 is the functionally dominant somatostatin receptor in human pancreatic β- and α-cells. Am J Physiol Endocrinol Metab. 2012 Nov 1;303(9):E1107-16. PMID: 22932785.

"

LKT S5747 [Tyr11]-Somatostatin 5 mg 324 Endogenous neuropeptide hormone; somatostatin agonist, GABA modulator, P/Q-type, N-type, and L-type voltage-gated Ca2+ channel modulator. 59481-27-5 ≥95% 1651.91 C76H102N18O20S2 CC(C1C(=O)NC(C(=O)NC(C(=O)NC(C(=O)NC(CSSCC(C(=O)NC(C(=O)NC(C(=O)NC(C(=O)NC(C(=O)NC(C(=O)NC(C(=O)N1)CCCCN)CC2=CC3=CC=CC=C3N2)CC4=CC=CC=C4)CC5=CC=CC=C5)CC(=O)N)CCCCN)NC(=O)CNC(=O)C(C)N)C(=O)O)CO)C(C)O)CC6=CC=C(C=C6)O)O Ambient -20°C "Stumm R. Somatostatin receptor sst2 reduces Akt activity and aggravates hypoxic/ischemic death in cerebral cortical neurons. Neuropharmacology. 2014 Feb;77:249-56. PMID: 24157493.

 

Takahashi M, Takeda M, Matsumoto S. Somatostatin enhances tooth-pulp-evoked cervical dorsal horn neuronal activity in the rat via inhibition of GABAergic interneurons. Brain Res Bull. 2014 Jan;100:76-83. PMID: 24321530.

 

Albrecht A, Thiere M, Bergado-Acosta JR, et al. Circadian modulation of anxiety: a role for somatostatin in the amygdala. PLoS One. 2013 Dec 20;8(12):e84668. PMID: 24376834.

 

Kovac S, Walker MC. Neuropeptides in epilepsy. Neuropeptides. 2013 Dec;47(6):467-75. PMID: 24210141.

 

Begg DP, Woods SC. Interactions between the central nervous system and pancreatic islet secretions: a historical perspective. Adv Physiol Educ. 2013 Mar;37(1):53-60. PMID: 23471249.

 

Schwetz TA, Ustione A, Piston DW. Neuropeptide Y and somatostatin inhibit insulin secretion through different mechanisms. Am J Physiol Endocrinol Metab. 2013 Jan 15;304(2):E211-21. PMID: 23211512.

 

Kailey B, van de Bunt M, Cheley S, et al. SSTR2 is the functionally dominant somatostatin receptor in human pancreatic β- and α-cells. Am J Physiol Endocrinol Metab. 2012 Nov 1;303(9):E1107-16. PMID: 22932785.

"

LKT M1749 Memantine Hydrochloride 25 mg 61.1 D2 agonist, NMDA, 5-HT3, α7 nAChR antagonist. 3,5-Dimethyltricyclo[3.3.1.13,7]decan-1-amine hydrochloride Akatinol 41100-52-1 ≥97% 215.77 C12H21N HCl CC12CC3CC(C1)(CC(C3)(C2)N)C.Cl Ambient Ambient Soluble in water. "Liu MY, Wang S, Yao WF, et al. Memantine improves spatial learning and memory impairments by regulating NGF signaling in APP/PS1 transgenic mice. Neuroscience. 2014 Jul 25;273:141-51. PMID: 24846616.

 

Wei H, Dobkin C, Sheikh AM, et al. The therapeutic effect of memantine through the stimulation of synapse formation and dendritic spine maturation in autism and fragile X syndrome. PLoS One. 2012;7(5):e36981. PMID: 22615862.

 

Aarsland D, Ballard C, Walker Z, et al. Memantine in patients with Parkinson's disease dementia or dementia with Lewy bodies: a double-blind, placebo-controlled, multicentre trial. Lancet Neurol. 2009 Jul;8(7):613-8. PMID: 19520613.

 

Seeman P, Caruso C, Lasaga M. Memantine agonist action at dopamine D2High receptors. Synapse. 2008 Feb;62(2):149-53. PMID: 18000814.

 

Aracava Y, Pereira EF, Maelicke A, et al. Memantine blocks alpha7* nicotinic acetylcholine receptors more potently than n-methyl-D-aspartate receptors in rat hippocampal neurons. J Pharmacol Exp Ther. 2005 Mar;312(3):1195-205. PMID: 15522999.

 

Rammes G, Rupprecht R, Ferrari U, et al. The N-methyl-D-aspartate receptor channel blockers memantine, MRZ 2/579 and other amino-alkyl-cyclohexanes antagonise 5-HT(3) receptor currents in cultured HEK-293 and N1E-115 cell systems in a non-competitive manner. Neurosci Lett. 2001 Jun 22;306(1-2):81-4. PMID: 11403963.

" None Not dangerous goods.

LKT M1749 Memantine Hydrochloride 100 mg 197.1 D2 agonist, NMDA, 5-HT3, α7 nAChR antagonist. 3,5-Dimethyltricyclo[3.3.1.13,7]decan-1-amine hydrochloride Akatinol 41100-52-1 ≥97% 215.77 C12H21N HCl CC12CC3CC(C1)(CC(C3)(C2)N)C.Cl Ambient Ambient Soluble in water. "Liu MY, Wang S, Yao WF, et al. Memantine improves spatial learning and memory impairments by regulating NGF signaling in APP/PS1 transgenic mice. Neuroscience. 2014 Jul 25;273:141-51. PMID: 24846616.

 

Wei H, Dobkin C, Sheikh AM, et al. The therapeutic effect of memantine through the stimulation of synapse formation and dendritic spine maturation in autism and fragile X syndrome. PLoS One. 2012;7(5):e36981. PMID: 22615862.

 

Aarsland D, Ballard C, Walker Z, et al. Memantine in patients with Parkinson's disease dementia or dementia with Lewy bodies: a double-blind, placebo-controlled, multicentre trial. Lancet Neurol. 2009 Jul;8(7):613-8. PMID: 19520613.

 

Seeman P, Caruso C, Lasaga M. Memantine agonist action at dopamine D2High receptors. Synapse. 2008 Feb;62(2):149-53. PMID: 18000814.

 

Aracava Y, Pereira EF, Maelicke A, et al. Memantine blocks alpha7* nicotinic acetylcholine receptors more potently than n-methyl-D-aspartate receptors in rat hippocampal neurons. J Pharmacol Exp Ther. 2005 Mar;312(3):1195-205. PMID: 15522999.

 

Rammes G, Rupprecht R, Ferrari U, et al. The N-methyl-D-aspartate receptor channel blockers memantine, MRZ 2/579 and other amino-alkyl-cyclohexanes antagonise 5-HT(3) receptor currents in cultured HEK-293 and N1E-115 cell systems in a non-competitive manner. Neurosci Lett. 2001 Jun 22;306(1-2):81-4. PMID: 11403963.

" None Not dangerous goods.

LKT M1752 Men 10376 0.5 mg 60 Peptide; NK2 antagonist. Neurokinin A(4-10), tyr(5)-trp(6,8,9)-lys(10)- 135306-85-3 ≥95% 1081.25 C57H68N12O10 CC(C)C(C(=O)NC(CC1=CNC2=CC=CC=C21)C(=O)NC(CC3=CNC4=CC=CC=C43)C(=O)NC(CCCCN)C(=O)N)NC(=O)C(CC5=CNC6=CC=CC=C65)NC(=O)C(CC7=CC=C(C=C7)O)NC(=O)C(CC(=O)O)N Ambient -20°C "Hernandez JM, Cox G, Janssen LJ. Involvement of the neurokinin-2 receptor in airway smooth muscle stretch-activated contractions assessed in perfused intact bovine bronchial segments. J Pharmacol Exp Ther. 2008 Nov;327(2):503-10. PMID: 18719290.

 

Krishnakumar S, Holmes EP, Moore RM, et al. Non-adrenergic non-cholinergic excitatory innervation in the airways: role of neurokinin-2 receptors. Auton Autacoid Pharmacol. 2002 Aug;22(4):215-24. PMID: 12656947.

" Not dangerous goods.

LKT S5746 Solanesol 50 mg 136 All-trans nonaprenol isoprenoid, found in Solanaceae family plants, used as biomarker for combustible tobacco use or exposure. "(2E,6E,10E,14E,18E,22E,26E,30E)-3,7,11,15,19,23,27,31,35-Nonamethyl-2,6,10,14,18,22,26,30,34-hexa- triacontanonaen-1-ol

" Nonaisoprenol 13190-97-1 ≥92% 631.07 C45H74O CC(=CCCC(=CCCC(=CCCC(=CCCC(=CCCC(=CCCC(=CCCC(=CCCC(=CCO)C)C)C)C)C)C)C)C)C Ambient -20°C Soluble in organic solvents. Insoluble in water. "Purkis SW, Troude V, Hill CA. Effect of puffing intensity on cigarette smoke yields. Regul Toxicol Pharmacol. 2013 Jun;66(1):72-82. PMID: 23523712.

 

Tomida A, Suzuki H. Synergistic effect in culture of bleomycin-group antibiotics and N-solanesyl-N,N'-bis(3,4-dimethoxybenzyl)ethylenediamine, a synthetic isoprenoid. Jpn J Cancer Res. 1990 Nov;81(11):1184-90. PMID: 1702416.

 

Suzuki H, Tomida A, Nishimura T. Cytocidal activity of a synthetic isoprenoid, N-solanesyl-N,N'-bis(3,4-dimethoxybenzyl)ethylenediamine, and its potentiation of antitumor drugs against multidrug-resistant and sensitive cells in vitro. Jpn J Cancer Res. 1990 Mar;81(3):298-303. PMID: 2161816.

" Not dangerous goods.

LKT M1752 Men 10376 1 mg 101.9 Peptide; NK2 antagonist. Neurokinin A(4-10), tyr(5)-trp(6,8,9)-lys(10)- 135306-85-3 ≥95% 1081.25 C57H68N12O10 CC(C)C(C(=O)NC(CC1=CNC2=CC=CC=C21)C(=O)NC(CC3=CNC4=CC=CC=C43)C(=O)NC(CCCCN)C(=O)N)NC(=O)C(CC5=CNC6=CC=CC=C65)NC(=O)C(CC7=CC=C(C=C7)O)NC(=O)C(CC(=O)O)N Ambient -20°C "Hernandez JM, Cox G, Janssen LJ. Involvement of the neurokinin-2 receptor in airway smooth muscle stretch-activated contractions assessed in perfused intact bovine bronchial segments. J Pharmacol Exp Ther. 2008 Nov;327(2):503-10. PMID: 18719290.

 

Krishnakumar S, Holmes EP, Moore RM, et al. Non-adrenergic non-cholinergic excitatory innervation in the airways: role of neurokinin-2 receptors. Auton Autacoid Pharmacol. 2002 Aug;22(4):215-24. PMID: 12656947.

" Not dangerous goods.

LKT M1752 Men 10376 2.5 mg 180 Peptide; NK2 antagonist. Neurokinin A(4-10), tyr(5)-trp(6,8,9)-lys(10)- 135306-85-3 ≥95% 1081.25 C57H68N12O10 CC(C)C(C(=O)NC(CC1=CNC2=CC=CC=C21)C(=O)NC(CC3=CNC4=CC=CC=C43)C(=O)NC(CCCCN)C(=O)N)NC(=O)C(CC5=CNC6=CC=CC=C65)NC(=O)C(CC7=CC=C(C=C7)O)NC(=O)C(CC(=O)O)N Ambient -20°C "Hernandez JM, Cox G, Janssen LJ. Involvement of the neurokinin-2 receptor in airway smooth muscle stretch-activated contractions assessed in perfused intact bovine bronchial segments. J Pharmacol Exp Ther. 2008 Nov;327(2):503-10. PMID: 18719290.

 

Krishnakumar S, Holmes EP, Moore RM, et al. Non-adrenergic non-cholinergic excitatory innervation in the airways: role of neurokinin-2 receptors. Auton Autacoid Pharmacol. 2002 Aug;22(4):215-24. PMID: 12656947.

" Not dangerous goods.

LKT S5746 Solanesol 100 mg 203.8 All-trans nonaprenol isoprenoid, found in Solanaceae family plants, used as biomarker for combustible tobacco use or exposure. "(2E,6E,10E,14E,18E,22E,26E,30E)-3,7,11,15,19,23,27,31,35-Nonamethyl-2,6,10,14,18,22,26,30,34-hexa- triacontanonaen-1-ol

" Nonaisoprenol 13190-97-1 ≥92% 631.07 C45H74O CC(=CCCC(=CCCC(=CCCC(=CCCC(=CCCC(=CCCC(=CCCC(=CCCC(=CCO)C)C)C)C)C)C)C)C)C Ambient -20°C Soluble in organic solvents. Insoluble in water. "Purkis SW, Troude V, Hill CA. Effect of puffing intensity on cigarette smoke yields. Regul Toxicol Pharmacol. 2013 Jun;66(1):72-82. PMID: 23523712.

 

Tomida A, Suzuki H. Synergistic effect in culture of bleomycin-group antibiotics and N-solanesyl-N,N'-bis(3,4-dimethoxybenzyl)ethylenediamine, a synthetic isoprenoid. Jpn J Cancer Res. 1990 Nov;81(11):1184-90. PMID: 1702416.

 

Suzuki H, Tomida A, Nishimura T. Cytocidal activity of a synthetic isoprenoid, N-solanesyl-N,N'-bis(3,4-dimethoxybenzyl)ethylenediamine, and its potentiation of antitumor drugs against multidrug-resistant and sensitive cells in vitro. Jpn J Cancer Res. 1990 Mar;81(3):298-303. PMID: 2161816.

" Not dangerous goods.

LKT S5746 Solanesol 500 mg 577.6 All-trans nonaprenol isoprenoid, found in Solanaceae family plants, used as biomarker for combustible tobacco use or exposure. "(2E,6E,10E,14E,18E,22E,26E,30E)-3,7,11,15,19,23,27,31,35-Nonamethyl-2,6,10,14,18,22,26,30,34-hexa- triacontanonaen-1-ol

" Nonaisoprenol 13190-97-1 ≥92% 631.07 C45H74O CC(=CCCC(=CCCC(=CCCC(=CCCC(=CCCC(=CCCC(=CCCC(=CCCC(=CCO)C)C)C)C)C)C)C)C)C Ambient -20°C Soluble in organic solvents. Insoluble in water. "Purkis SW, Troude V, Hill CA. Effect of puffing intensity on cigarette smoke yields. Regul Toxicol Pharmacol. 2013 Jun;66(1):72-82. PMID: 23523712.

 

Tomida A, Suzuki H. Synergistic effect in culture of bleomycin-group antibiotics and N-solanesyl-N,N'-bis(3,4-dimethoxybenzyl)ethylenediamine, a synthetic isoprenoid. Jpn J Cancer Res. 1990 Nov;81(11):1184-90. PMID: 1702416.

 

Suzuki H, Tomida A, Nishimura T. Cytocidal activity of a synthetic isoprenoid, N-solanesyl-N,N'-bis(3,4-dimethoxybenzyl)ethylenediamine, and its potentiation of antitumor drugs against multidrug-resistant and sensitive cells in vitro. Jpn J Cancer Res. 1990 Mar;81(3):298-303. PMID: 2161816.

" Not dangerous goods.

LKT M1770 Meropenem Sodium Carbonate 25 mg 40.7 Carbapenem β-lactam; penicillin binding protein inhibitor. (4R,5S,6S)-3-[[(3S,5S)5-[(Dimethylamino)carbonyl]-3-pyrrolidinyl]thio]-6-((1R)-1-hydroxyethyl)-4-methyl-7-oxo-1-azabicyclo[3,2,0]hept-2-ene-2-carboxyloc acid Merrem 96036-03-2 ≥81% 383.46 C17H25N3O5S CC1C2C(C(=O)N2C(=C1SC3CC(NC3)C(=O)N(C)C)C(=O)O)C(C)O Stable at room temperature. Ambient 4°C Soluble in water "Guzek A, Tomaszewski D, Rybicki Z, et al. Comparison of in vitro efficacy of ertapenem, imipenem and meropenem in the infections caused by the Enterobacteriaceae strains family. Anaesthesiol Intensive Ther. 2013 Apr-Jun;45(2):67-72. PMID: 23877897.

 

Li WJ, Li DF, Hu YL, et al. Crystal structure of L,D-transpeptidase LdtMt2 in complex with meropenem reveals the mechanism of carbapenem against Mycobacterium tuberculosis. Cell Res. 2013 May;23(5):728-31. PMID: 23588382.

 

Louie A, VanScoy BD, Brown DL, et al. Impact of spores on the comparative efficacies of five antibiotics for treatment of Bacillus anthracis in an in vitro hollow fiber pharmacodynamic model. Antimicrob Agents Chemother. 2012 Mar;56(3):1229-39. PMID: 22155821.

 

Isozumi R, Yoshimatsu K, Yamashiro T, et al. bla(NDM-1)-positive Klebsiella pneumoniae from environment, Vietnam. Emerg Infect Dis. 2012 Aug;18(8):1383-1385. PMID: 22840532.

" Xi Not dangerous goods.

LKT M1770 Meropenem Sodium Carbonate 100 mg 129 Carbapenem β-lactam; penicillin binding protein inhibitor. (4R,5S,6S)-3-[[(3S,5S)5-[(Dimethylamino)carbonyl]-3-pyrrolidinyl]thio]-6-((1R)-1-hydroxyethyl)-4-methyl-7-oxo-1-azabicyclo[3,2,0]hept-2-ene-2-carboxyloc acid Merrem 96036-03-2 ≥81% 383.46 C17H25N3O5S CC1C2C(C(=O)N2C(=C1SC3CC(NC3)C(=O)N(C)C)C(=O)O)C(C)O Stable at room temperature. Ambient 4°C Soluble in water "Guzek A, Tomaszewski D, Rybicki Z, et al. Comparison of in vitro efficacy of ertapenem, imipenem and meropenem in the infections caused by the Enterobacteriaceae strains family. Anaesthesiol Intensive Ther. 2013 Apr-Jun;45(2):67-72. PMID: 23877897.

 

Li WJ, Li DF, Hu YL, et al. Crystal structure of L,D-transpeptidase LdtMt2 in complex with meropenem reveals the mechanism of carbapenem against Mycobacterium tuberculosis. Cell Res. 2013 May;23(5):728-31. PMID: 23588382.

 

Louie A, VanScoy BD, Brown DL, et al. Impact of spores on the comparative efficacies of five antibiotics for treatment of Bacillus anthracis in an in vitro hollow fiber pharmacodynamic model. Antimicrob Agents Chemother. 2012 Mar;56(3):1229-39. PMID: 22155821.

 

Isozumi R, Yoshimatsu K, Yamashiro T, et al. bla(NDM-1)-positive Klebsiella pneumoniae from environment, Vietnam. Emerg Infect Dis. 2012 Aug;18(8):1383-1385. PMID: 22840532.

" Xi Not dangerous goods.

LKT M1770 Meropenem Sodium Carbonate 500 mg 407.7 Carbapenem β-lactam; penicillin binding protein inhibitor. (4R,5S,6S)-3-[[(3S,5S)5-[(Dimethylamino)carbonyl]-3-pyrrolidinyl]thio]-6-((1R)-1-hydroxyethyl)-4-methyl-7-oxo-1-azabicyclo[3,2,0]hept-2-ene-2-carboxyloc acid Merrem 96036-03-2 ≥81% 383.46 C17H25N3O5S CC1C2C(C(=O)N2C(=C1SC3CC(NC3)C(=O)N(C)C)C(=O)O)C(C)O Stable at room temperature. Ambient 4°C Soluble in water "Guzek A, Tomaszewski D, Rybicki Z, et al. Comparison of in vitro efficacy of ertapenem, imipenem and meropenem in the infections caused by the Enterobacteriaceae strains family. Anaesthesiol Intensive Ther. 2013 Apr-Jun;45(2):67-72. PMID: 23877897.

 

Li WJ, Li DF, Hu YL, et al. Crystal structure of L,D-transpeptidase LdtMt2 in complex with meropenem reveals the mechanism of carbapenem against Mycobacterium tuberculosis. Cell Res. 2013 May;23(5):728-31. PMID: 23588382.

 

Louie A, VanScoy BD, Brown DL, et al. Impact of spores on the comparative efficacies of five antibiotics for treatment of Bacillus anthracis in an in vitro hollow fiber pharmacodynamic model. Antimicrob Agents Chemother. 2012 Mar;56(3):1229-39. PMID: 22155821.

 

Isozumi R, Yoshimatsu K, Yamashiro T, et al. bla(NDM-1)-positive Klebsiella pneumoniae from environment, Vietnam. Emerg Infect Dis. 2012 Aug;18(8):1383-1385. PMID: 22840532.

" Xi Not dangerous goods.

LKT M1774 2-Mercaptoethanesulfonate Sodium 5 g 47.6 Organosulfur, antioxidant. 2-Mercaptoethanesulfonic acid sodium salt; MESNA 19767-45-4 ≥98% 164.18 C2H5O3S2 Na C(CS(=O)(=O)[O-])S.[Na+] Ambient Ambient Soluble in water. Slightly soluble in alcohol. Practically insoluble in cyclohexane. "Bogiatzi S, Pagonopoulou O, Simopoulou M, et al. The cytogenetic action of ifosfamide, mesna, and their combination on peripheral rabbit lymphocytes: an in vivo/in vitro cytogenetic study. Cytotechnology. 2014 Oct;66(5):753-60. PMID: 23949582.

 

Vincenti V, Magnan J, Saccardi MS, et al. Chemically Assisted Dissection by Means of Mesna in Cholesteatoma Surgery. Otol Neurotol. 2014 Jul 14. [Epub ahead of print]. PMID: 25025536.

 

Li X, Yang S, Lv X, et al. The mechanism of mesna in protection from cisplatin-induced ovarian damage in female rats. J Gynecol Oncol. 2013 Apr;24(2):177-85. PMID: 23653836.

" Xi Not dangerous goods.

LKT M1774 2-Mercaptoethanesulfonate Sodium 10 g 88.3 Organosulfur, antioxidant. 2-Mercaptoethanesulfonic acid sodium salt; MESNA 19767-45-4 ≥98% 164.18 C2H5O3S2 Na C(CS(=O)(=O)[O-])S.[Na+] Ambient Ambient Soluble in water. Slightly soluble in alcohol. Practically insoluble in cyclohexane. "Bogiatzi S, Pagonopoulou O, Simopoulou M, et al. The cytogenetic action of ifosfamide, mesna, and their combination on peripheral rabbit lymphocytes: an in vivo/in vitro cytogenetic study. Cytotechnology. 2014 Oct;66(5):753-60. PMID: 23949582.

 

Vincenti V, Magnan J, Saccardi MS, et al. Chemically Assisted Dissection by Means of Mesna in Cholesteatoma Surgery. Otol Neurotol. 2014 Jul 14. [Epub ahead of print]. PMID: 25025536.

 

Li X, Yang S, Lv X, et al. The mechanism of mesna in protection from cisplatin-induced ovarian damage in female rats. J Gynecol Oncol. 2013 Apr;24(2):177-85. PMID: 23653836.

" Xi Not dangerous goods.

LKT M1774 2-Mercaptoethanesulfonate Sodium 25 g 169.9 Organosulfur, antioxidant. 2-Mercaptoethanesulfonic acid sodium salt; MESNA 19767-45-4 ≥98% 164.18 C2H5O3S2 Na C(CS(=O)(=O)[O-])S.[Na+] Ambient Ambient Soluble in water. Slightly soluble in alcohol. Practically insoluble in cyclohexane. "Bogiatzi S, Pagonopoulou O, Simopoulou M, et al. The cytogenetic action of ifosfamide, mesna, and their combination on peripheral rabbit lymphocytes: an in vivo/in vitro cytogenetic study. Cytotechnology. 2014 Oct;66(5):753-60. PMID: 23949582.

 

Vincenti V, Magnan J, Saccardi MS, et al. Chemically Assisted Dissection by Means of Mesna in Cholesteatoma Surgery. Otol Neurotol. 2014 Jul 14. [Epub ahead of print]. PMID: 25025536.

 

Li X, Yang S, Lv X, et al. The mechanism of mesna in protection from cisplatin-induced ovarian damage in female rats. J Gynecol Oncol. 2013 Apr;24(2):177-85. PMID: 23653836.

" Xi Not dangerous goods.

LKT S5745 [Tyr1]-Somatostatin 1 mg 107.8 Endogenous neuropeptide hormone; somatostatin agonist, GABA modulator, P/Q-type, N-type, and L-type voltage-gated Ca2+ channel modulator. 59481-23-1 ≥95% 1730.01 C82H108N18O20S2 CC(C1C(=O)NC(C(=O)NC(C(=O)NC(C(=O)NC(CSSCC(C(=O)NC(C(=O)NC(C(=O)NC(C(=O)NC(C(=O)NC(C(=O)NC(C(=O)N1)CCCCN)CC2=CNC3=CC=CC=C32)CC4=CC=CC=C4)CC5=CC=CC=C5)CC(=O)N)CCCCN)NC(=O)CNC(=O)C(C)N)C(=O)O)CO)C(C)O)CC6=CC=CC=C6)O Ambient -20°C "Stumm R. Somatostatin receptor sst2 reduces Akt activity and aggravates hypoxic/ischemic death in cerebral cortical neurons. Neuropharmacology. 2014 Feb;77:249-56. PMID: 24157493.

 

Takahashi M, Takeda M, Matsumoto S. Somatostatin enhances tooth-pulp-evoked cervical dorsal horn neuronal activity in the rat via inhibition of GABAergic interneurons. Brain Res Bull. 2014 Jan;100:76-83. PMID: 24321530.

 

Albrecht A, Thiere M, Bergado-Acosta JR, et al. Circadian modulation of anxiety: a role for somatostatin in the amygdala. PLoS One. 2013 Dec 20;8(12):e84668. PMID: 24376834.

 

Kovac S, Walker MC. Neuropeptides in epilepsy. Neuropeptides. 2013 Dec;47(6):467-75. PMID: 24210141.

 

Begg DP, Woods SC. Interactions between the central nervous system and pancreatic islet secretions: a historical perspective. Adv Physiol Educ. 2013 Mar;37(1):53-60. PMID: 23471249.

 

Schwetz TA, Ustione A, Piston DW. Neuropeptide Y and somatostatin inhibit insulin secretion through different mechanisms. Am J Physiol Endocrinol Metab. 2013 Jan 15;304(2):E211-21. PMID: 23211512.

 

Kailey B, van de Bunt M, Cheley S, et al. SSTR2 is the functionally dominant somatostatin receptor in human pancreatic β- and α-cells. Am J Physiol Endocrinol Metab. 2012 Nov 1;303(9):E1107-16. PMID: 22932785.

"

LKT S5745 [Tyr1]-Somatostatin 2 mg 183 Endogenous neuropeptide hormone; somatostatin agonist, GABA modulator, P/Q-type, N-type, and L-type voltage-gated Ca2+ channel modulator. 59481-23-1 ≥95% 1730.01 C82H108N18O20S2 CC(C1C(=O)NC(C(=O)NC(C(=O)NC(C(=O)NC(CSSCC(C(=O)NC(C(=O)NC(C(=O)NC(C(=O)NC(C(=O)NC(C(=O)NC(C(=O)N1)CCCCN)CC2=CNC3=CC=CC=C32)CC4=CC=CC=C4)CC5=CC=CC=C5)CC(=O)N)CCCCN)NC(=O)CNC(=O)C(C)N)C(=O)O)CO)C(C)O)CC6=CC=CC=C6)O Ambient -20°C "Stumm R. Somatostatin receptor sst2 reduces Akt activity and aggravates hypoxic/ischemic death in cerebral cortical neurons. Neuropharmacology. 2014 Feb;77:249-56. PMID: 24157493.

 

Takahashi M, Takeda M, Matsumoto S. Somatostatin enhances tooth-pulp-evoked cervical dorsal horn neuronal activity in the rat via inhibition of GABAergic interneurons. Brain Res Bull. 2014 Jan;100:76-83. PMID: 24321530.

 

Albrecht A, Thiere M, Bergado-Acosta JR, et al. Circadian modulation of anxiety: a role for somatostatin in the amygdala. PLoS One. 2013 Dec 20;8(12):e84668. PMID: 24376834.

 

Kovac S, Walker MC. Neuropeptides in epilepsy. Neuropeptides. 2013 Dec;47(6):467-75. PMID: 24210141.

 

Begg DP, Woods SC. Interactions between the central nervous system and pancreatic islet secretions: a historical perspective. Adv Physiol Educ. 2013 Mar;37(1):53-60. PMID: 23471249.

 

Schwetz TA, Ustione A, Piston DW. Neuropeptide Y and somatostatin inhibit insulin secretion through different mechanisms. Am J Physiol Endocrinol Metab. 2013 Jan 15;304(2):E211-21. PMID: 23211512.

 

Kailey B, van de Bunt M, Cheley S, et al. SSTR2 is the functionally dominant somatostatin receptor in human pancreatic β- and α-cells. Am J Physiol Endocrinol Metab. 2012 Nov 1;303(9):E1107-16. PMID: 22932785.

"

LKT S5745 [Tyr1]-Somatostatin 5 mg 324 Endogenous neuropeptide hormone; somatostatin agonist, GABA modulator, P/Q-type, N-type, and L-type voltage-gated Ca2+ channel modulator. 59481-23-1 ≥95% 1730.01 C82H108N18O20S2 CC(C1C(=O)NC(C(=O)NC(C(=O)NC(C(=O)NC(CSSCC(C(=O)NC(C(=O)NC(C(=O)NC(C(=O)NC(C(=O)NC(C(=O)NC(C(=O)N1)CCCCN)CC2=CNC3=CC=CC=C32)CC4=CC=CC=C4)CC5=CC=CC=C5)CC(=O)N)CCCCN)NC(=O)CNC(=O)C(C)N)C(=O)O)CO)C(C)O)CC6=CC=CC=C6)O Ambient -20°C "Stumm R. Somatostatin receptor sst2 reduces Akt activity and aggravates hypoxic/ischemic death in cerebral cortical neurons. Neuropharmacology. 2014 Feb;77:249-56. PMID: 24157493.

 

Takahashi M, Takeda M, Matsumoto S. Somatostatin enhances tooth-pulp-evoked cervical dorsal horn neuronal activity in the rat via inhibition of GABAergic interneurons. Brain Res Bull. 2014 Jan;100:76-83. PMID: 24321530.

 

Albrecht A, Thiere M, Bergado-Acosta JR, et al. Circadian modulation of anxiety: a role for somatostatin in the amygdala. PLoS One. 2013 Dec 20;8(12):e84668. PMID: 24376834.

 

Kovac S, Walker MC. Neuropeptides in epilepsy. Neuropeptides. 2013 Dec;47(6):467-75. PMID: 24210141.

 

Begg DP, Woods SC. Interactions between the central nervous system and pancreatic islet secretions: a historical perspective. Adv Physiol Educ. 2013 Mar;37(1):53-60. PMID: 23471249.

 

Schwetz TA, Ustione A, Piston DW. Neuropeptide Y and somatostatin inhibit insulin secretion through different mechanisms. Am J Physiol Endocrinol Metab. 2013 Jan 15;304(2):E211-21. PMID: 23211512.

 

Kailey B, van de Bunt M, Cheley S, et al. SSTR2 is the functionally dominant somatostatin receptor in human pancreatic β- and α-cells. Am J Physiol Endocrinol Metab. 2012 Nov 1;303(9):E1107-16. PMID: 22932785.

"

LKT M1776 α-Methylbenzyl Isothiocyanate 5 g 105.2 ITC. 1-Phenylethyl isothiocyanate DL-α-Methylbenzyl isothiocyanate 32393-32-1 ≥98% 163.24 C9H9NS CC(C1=CC=CC=C1)N=C=S Ambient 4°C Soluble in water. Munday R, Zhang Y, Munday CM, et al. Structure-activity relationships and organ specificity in the induction of GST and NQO1 by alkyl-aryl isothiocyanates. Pharm Res. 2008 Sep;25(9):2164-70. PMID: 18563540. C, Xn "UN number: 2922     Class: 8 (6.1)     Packing Group: III

Proper shipping name: Corrosive liquid, toxic, n.o.s. (Methylbenzyl isothiocyanate)"

LKT M1776 α-Methylbenzyl Isothiocyanate 10 g 180 ITC. 1-Phenylethyl isothiocyanate DL-α-Methylbenzyl isothiocyanate 32393-32-1 ≥98% 163.24 C9H9NS CC(C1=CC=CC=C1)N=C=S Ambient 4°C Soluble in water. Munday R, Zhang Y, Munday CM, et al. Structure-activity relationships and organ specificity in the induction of GST and NQO1 by alkyl-aryl isothiocyanates. Pharm Res. 2008 Sep;25(9):2164-70. PMID: 18563540. C, Xn "UN number: 2922     Class: 8 (6.1)     Packing Group: III

Proper shipping name: Corrosive liquid, toxic, n.o.s. (Methylbenzyl isothiocyanate)"

LKT M1777 R-(−)-α-Methylbenzyl Isothiocyanate 1 g 60.4 ITC, used as chiral agent. L-α-Methylbenzyl isothiocyanate 24277-44-9 ≥98% 163.24 C9H9NS CC(C1=CC=CC=C1)N=C=S Ambient 4°C Munday R, Zhang Y, Munday CM, et al. Structure-activity relationships and organ specificity in the induction of GST and NQO1 by alkyl-aryl isothiocyanates. Pharm Res. 2008 Sep;25(9):2164-70. PMID: 18563540. C, Xn "UN number: 2922     Class: 8 (6.1)     Packing Group: III

Proper shipping name: Corrosive liquid, toxic, n.o.s. (Methylbenzyl isothiocyanate)"

LKT M1777 R-(−)-α-Methylbenzyl Isothiocyanate 5 g 240.1 ITC, used as chiral agent. L-α-Methylbenzyl isothiocyanate 24277-44-9 ≥98% 163.24 C9H9NS CC(C1=CC=CC=C1)N=C=S Ambient 4°C Munday R, Zhang Y, Munday CM, et al. Structure-activity relationships and organ specificity in the induction of GST and NQO1 by alkyl-aryl isothiocyanates. Pharm Res. 2008 Sep;25(9):2164-70. PMID: 18563540. C, Xn "UN number: 2922     Class: 8 (6.1)     Packing Group: III

Proper shipping name: Corrosive liquid, toxic, n.o.s. (Methylbenzyl isothiocyanate)"

LKT M1777 R-(−)-α-Methylbenzyl Isothiocyanate 10 g 407.6 ITC, used as chiral agent. L-α-Methylbenzyl isothiocyanate 24277-44-9 ≥98% 163.24 C9H9NS CC(C1=CC=CC=C1)N=C=S Ambient 4°C Munday R, Zhang Y, Munday CM, et al. Structure-activity relationships and organ specificity in the induction of GST and NQO1 by alkyl-aryl isothiocyanates. Pharm Res. 2008 Sep;25(9):2164-70. PMID: 18563540. C, Xn "UN number: 2922     Class: 8 (6.1)     Packing Group: III

Proper shipping name: Corrosive liquid, toxic, n.o.s. (Methylbenzyl isothiocyanate)"

LKT S5200 SNA 1 1 mg 201.8 Sialic-acid sensing lectin. ≥98% Ambient -20°C Kirkeby S, Martel CJ, Aasted B, et al. Carbohydrate determinants in ferret conjunctiva are affected by infection with influenza H1N1 virus. Curr Eye Res. 2013 Oct;38(10):1027-35. PMID: 23790131.

LKT M1778 S-(+)-α−Methylbenzyl Isothiocyanate 1 g 58.8 ITC, used as chiral agent. D-α-Methylbenzyl isothiocyanate 24277-43-8 ≥98% 163.24 C9H9NS CC(C1=CC=CC=C1)N=C=S Moisture Sensitive Ambient 4°C Munday R, Zhang Y, Munday CM, et al. Structure-activity relationships and organ specificity in the induction of GST and NQO1 by alkyl-aryl isothiocyanates. Pharm Res. 2008 Sep;25(9):2164-70. PMID: 18563540. C, Xn "UN number: 2922     Class: 8 (6.1)     Packing Group: III

Proper shipping name: Corrosive liquid, toxic, n.o.s. (Methylbenzyl isothiocyanate)"

LKT M1778 S-(+)-α−Methylbenzyl Isothiocyanate 5 g 234 ITC, used as chiral agent. D-α-Methylbenzyl isothiocyanate 24277-43-8 ≥98% 163.24 C9H9NS CC(C1=CC=CC=C1)N=C=S Moisture Sensitive Ambient 4°C Munday R, Zhang Y, Munday CM, et al. Structure-activity relationships and organ specificity in the induction of GST and NQO1 by alkyl-aryl isothiocyanates. Pharm Res. 2008 Sep;25(9):2164-70. PMID: 18563540. C, Xn "UN number: 2922     Class: 8 (6.1)     Packing Group: III

Proper shipping name: Corrosive liquid, toxic, n.o.s. (Methylbenzyl isothiocyanate)"

LKT M1778 S-(+)-α−Methylbenzyl Isothiocyanate 10 g 389.8 ITC, used as chiral agent. D-α-Methylbenzyl isothiocyanate 24277-43-8 ≥98% 163.24 C9H9NS CC(C1=CC=CC=C1)N=C=S Moisture Sensitive Ambient 4°C Munday R, Zhang Y, Munday CM, et al. Structure-activity relationships and organ specificity in the induction of GST and NQO1 by alkyl-aryl isothiocyanates. Pharm Res. 2008 Sep;25(9):2164-70. PMID: 18563540. C, Xn "UN number: 2922     Class: 8 (6.1)     Packing Group: III

Proper shipping name: Corrosive liquid, toxic, n.o.s. (Methylbenzyl isothiocyanate)"

LKT M1779 Methyldopa Sesquihydrate 1 g 38.8 DOPA decarboxylase inhibitor, indirect α2-adrenergic agonist. 3-Hydroxy-α-methyl-L-tyrosine sesquihydrate Methyl-L-DOPA; MK-351; Hyperax 41372-08-1 ≥98% 238.24 C10H13NO4 3/2H2O CC(CC1=CC(=C(C=C1)O)O)(C(=O)O)N.CC(CC1=CC(=C(C=C1)O)O)(C(=O)O)N.O.O.O Very hygroscopic. Ambient Ambient Soluble in dilute mineral acids and water (10mg/mL, pH 5.0). Insoluble in organic solvents.  "Sucak A, Kanat-Pektas M, Gungor T, et al. Leptin levels and antihypertensive treatment in preeclampsia. Singapore Med J. 2010 Jan;51(1):39-43. PMID: 20200774.

 

Soares de Moura R, Rios AA, et al. The effects of nitric oxide synthase inhibitors on the sedative effect of clonidine. Anesth Analg. 2001 Nov;93(5):1217-21. PMID: 11682401.

" Xn, Xi Not dangerous goods.

LKT M1779 Methyldopa Sesquihydrate 5 g 54.4 DOPA decarboxylase inhibitor, indirect α2-adrenergic agonist. 3-Hydroxy-α-methyl-L-tyrosine sesquihydrate Methyl-L-DOPA; MK-351; Hyperax 41372-08-1 ≥98% 238.24 C10H13NO4 3/2H2O CC(CC1=CC(=C(C=C1)O)O)(C(=O)O)N.CC(CC1=CC(=C(C=C1)O)O)(C(=O)O)N.O.O.O Very hygroscopic. Ambient Ambient Soluble in dilute mineral acids and water (10mg/mL, pH 5.0). Insoluble in organic solvents.  "Sucak A, Kanat-Pektas M, Gungor T, et al. Leptin levels and antihypertensive treatment in preeclampsia. Singapore Med J. 2010 Jan;51(1):39-43. PMID: 20200774.

 

Soares de Moura R, Rios AA, et al. The effects of nitric oxide synthase inhibitors on the sedative effect of clonidine. Anesth Analg. 2001 Nov;93(5):1217-21. PMID: 11682401.

" Xn, Xi Not dangerous goods.

LKT M1779 Methyldopa Sesquihydrate 10 g 97 DOPA decarboxylase inhibitor, indirect α2-adrenergic agonist. 3-Hydroxy-α-methyl-L-tyrosine sesquihydrate Methyl-L-DOPA; MK-351; Hyperax 41372-08-1 ≥98% 238.24 C10H13NO4 3/2H2O CC(CC1=CC(=C(C=C1)O)O)(C(=O)O)N.CC(CC1=CC(=C(C=C1)O)O)(C(=O)O)N.O.O.O Very hygroscopic. Ambient Ambient Soluble in dilute mineral acids and water (10mg/mL, pH 5.0). Insoluble in organic solvents.  "Sucak A, Kanat-Pektas M, Gungor T, et al. Leptin levels and antihypertensive treatment in preeclampsia. Singapore Med J. 2010 Jan;51(1):39-43. PMID: 20200774.

 

Soares de Moura R, Rios AA, et al. The effects of nitric oxide synthase inhibitors on the sedative effect of clonidine. Anesth Analg. 2001 Nov;93(5):1217-21. PMID: 11682401.

" Xn, Xi Not dangerous goods.

LKT S3586 SIVmac239-2 1 mg 96 Peptide, SIV fragment. ≥95% 1630.87 C70H123N19O25 Ambient -20°C "Münch J, Sauermann U, Yolamanova M, et al. Effect of semen and seminal amyloid on vaginal transmission of simian immunodeficiency virus. Retrovirology. 2013 Dec 5;10:148. PMID: 24308721.

 

Xu Y, Weatherall C, Bailey M, et al. Simian immunodeficiency virus infects follicular helper CD4 T cells in lymphoid tissues during pathogenic infection of pigtail macaques. J Virol. 2013 Apr;87(7):3760-73. PMID: 23325697.

 

Luciw PA, Shaw KE, Unger RE, et al. Genetic and biological comparisons of pathogenic and nonpathogenic molecular clones of simian immunodeficiency virus (SIVmac). AIDS Res Hum Retroviruses. 1992 Mar;8(3):395-402. PMID: 1571198.

 

Naidu YM, Kestler HW 3rd, Li Y, et al. Characterization of infectious molecular clones of simian immunodeficiency virus (SIVmac) and human immunodeficiency virus type 2: persistent infection of rhesus monkeys with molecularly cloned SIVmac. J Virol. 1988 Dec;62(12):4691-6. PMID: 2846880.

"

LKT S3586 SIVmac239-2 2 mg 162 Peptide, SIV fragment. ≥95% 1630.87 C70H123N19O25 Ambient -20°C "Münch J, Sauermann U, Yolamanova M, et al. Effect of semen and seminal amyloid on vaginal transmission of simian immunodeficiency virus. Retrovirology. 2013 Dec 5;10:148. PMID: 24308721.

 

Xu Y, Weatherall C, Bailey M, et al. Simian immunodeficiency virus infects follicular helper CD4 T cells in lymphoid tissues during pathogenic infection of pigtail macaques. J Virol. 2013 Apr;87(7):3760-73. PMID: 23325697.

 

Luciw PA, Shaw KE, Unger RE, et al. Genetic and biological comparisons of pathogenic and nonpathogenic molecular clones of simian immunodeficiency virus (SIVmac). AIDS Res Hum Retroviruses. 1992 Mar;8(3):395-402. PMID: 1571198.

 

Naidu YM, Kestler HW 3rd, Li Y, et al. Characterization of infectious molecular clones of simian immunodeficiency virus (SIVmac) and human immunodeficiency virus type 2: persistent infection of rhesus monkeys with molecularly cloned SIVmac. J Virol. 1988 Dec;62(12):4691-6. PMID: 2846880.

"

LKT S3586 SIVmac239-2 5 mg 287.9 Peptide, SIV fragment. ≥95% 1630.87 C70H123N19O25 Ambient -20°C "Münch J, Sauermann U, Yolamanova M, et al. Effect of semen and seminal amyloid on vaginal transmission of simian immunodeficiency virus. Retrovirology. 2013 Dec 5;10:148. PMID: 24308721.

 

Xu Y, Weatherall C, Bailey M, et al. Simian immunodeficiency virus infects follicular helper CD4 T cells in lymphoid tissues during pathogenic infection of pigtail macaques. J Virol. 2013 Apr;87(7):3760-73. PMID: 23325697.

 

Luciw PA, Shaw KE, Unger RE, et al. Genetic and biological comparisons of pathogenic and nonpathogenic molecular clones of simian immunodeficiency virus (SIVmac). AIDS Res Hum Retroviruses. 1992 Mar;8(3):395-402. PMID: 1571198.

 

Naidu YM, Kestler HW 3rd, Li Y, et al. Characterization of infectious molecular clones of simian immunodeficiency virus (SIVmac) and human immunodeficiency virus type 2: persistent infection of rhesus monkeys with molecularly cloned SIVmac. J Virol. 1988 Dec;62(12):4691-6. PMID: 2846880.

"

LKT M1826 Meglumine 100 g 46.2 Amino sugar, sorbitol derivative, used as a bulking agent. 1-Deoxy-1-(methylamino)-D-glucitol N-Methylglucamine; Meglumine 6284-40-8 ≥98% 195.21 C7H17NO5 CNCC(C(C(C(CO)O)O)O)O Ambient Ambient Soluble in water and alcohol. "Borborema SE, Schwendener RA, Osso JA Jr, et al. Uptake and antileishmanial activity of meglumine antimoniate-containing liposomes in Leishmania (Leishmania) major-infected macrophages. Int J Antimicrob Agents. 2011 Oct;38(4):341-7. PMID: 21783345.

 

Rossetti RC, Perdigão A, Mesquita FS, et al. Effects of flunixin meglumine, recombinant bovine somatotropin and/or human chorionic gonadotropin on pregnancy rates in Nelore cows. Theriogenology. 2011 Sep 1;76(4):751-8. PMID: 21719091.

" Not dangerous goods.

LKT M1826 Meglumine 500 g 164.9 Amino sugar, sorbitol derivative, used as a bulking agent. 1-Deoxy-1-(methylamino)-D-glucitol N-Methylglucamine; Meglumine 6284-40-8 ≥98% 195.21 C7H17NO5 CNCC(C(C(C(CO)O)O)O)O Ambient Ambient Soluble in water and alcohol. "Borborema SE, Schwendener RA, Osso JA Jr, et al. Uptake and antileishmanial activity of meglumine antimoniate-containing liposomes in Leishmania (Leishmania) major-infected macrophages. Int J Antimicrob Agents. 2011 Oct;38(4):341-7. PMID: 21783345.

 

Rossetti RC, Perdigão A, Mesquita FS, et al. Effects of flunixin meglumine, recombinant bovine somatotropin and/or human chorionic gonadotropin on pregnancy rates in Nelore cows. Theriogenology. 2011 Sep 1;76(4):751-8. PMID: 21719091.

" Not dangerous goods.

LKT M1826 Meglumine 1 kg 296.1 Amino sugar, sorbitol derivative, used as a bulking agent. 1-Deoxy-1-(methylamino)-D-glucitol N-Methylglucamine; Meglumine 6284-40-8 ≥98% 195.21 C7H17NO5 CNCC(C(C(C(CO)O)O)O)O Ambient Ambient Soluble in water and alcohol. "Borborema SE, Schwendener RA, Osso JA Jr, et al. Uptake and antileishmanial activity of meglumine antimoniate-containing liposomes in Leishmania (Leishmania) major-infected macrophages. Int J Antimicrob Agents. 2011 Oct;38(4):341-7. PMID: 21783345.

 

Rossetti RC, Perdigão A, Mesquita FS, et al. Effects of flunixin meglumine, recombinant bovine somatotropin and/or human chorionic gonadotropin on pregnancy rates in Nelore cows. Theriogenology. 2011 Sep 1;76(4):751-8. PMID: 21719091.

" Not dangerous goods.

LKT S3585 SIVmac239-1 1 mg 96 Peptide, SIV fragment. ≥95% 1590.83 C65H115N21O23S1 Ambient -20°C "Münch J, Sauermann U, Yolamanova M, et al. Effect of semen and seminal amyloid on vaginal transmission of simian immunodeficiency virus. Retrovirology. 2013 Dec 5;10:148. PMID: 24308721.

 

Xu Y, Weatherall C, Bailey M, et al. Simian immunodeficiency virus infects follicular helper CD4 T cells in lymphoid tissues during pathogenic infection of pigtail macaques. J Virol. 2013 Apr;87(7):3760-73. PMID: 23325697.

 

Luciw PA, Shaw KE, Unger RE, et al. Genetic and biological comparisons of pathogenic and nonpathogenic molecular clones of simian immunodeficiency virus (SIVmac). AIDS Res Hum Retroviruses. 1992 Mar;8(3):395-402. PMID: 1571198.

 

Naidu YM, Kestler HW 3rd, Li Y, et al. Characterization of infectious molecular clones of simian immunodeficiency virus (SIVmac) and human immunodeficiency virus type 2: persistent infection of rhesus monkeys with molecularly cloned SIVmac. J Virol. 1988 Dec;62(12):4691-6. PMID: 2846880.

"

LKT S3585 SIVmac239-1 2 mg 162 Peptide, SIV fragment. ≥95% 1590.83 C65H115N21O23S1 Ambient -20°C "Münch J, Sauermann U, Yolamanova M, et al. Effect of semen and seminal amyloid on vaginal transmission of simian immunodeficiency virus. Retrovirology. 2013 Dec 5;10:148. PMID: 24308721.

 

Xu Y, Weatherall C, Bailey M, et al. Simian immunodeficiency virus infects follicular helper CD4 T cells in lymphoid tissues during pathogenic infection of pigtail macaques. J Virol. 2013 Apr;87(7):3760-73. PMID: 23325697.

 

Luciw PA, Shaw KE, Unger RE, et al. Genetic and biological comparisons of pathogenic and nonpathogenic molecular clones of simian immunodeficiency virus (SIVmac). AIDS Res Hum Retroviruses. 1992 Mar;8(3):395-402. PMID: 1571198.

 

Naidu YM, Kestler HW 3rd, Li Y, et al. Characterization of infectious molecular clones of simian immunodeficiency virus (SIVmac) and human immunodeficiency virus type 2: persistent infection of rhesus monkeys with molecularly cloned SIVmac. J Virol. 1988 Dec;62(12):4691-6. PMID: 2846880.

"

LKT S3585 SIVmac239-1 5 mg 287.9 Peptide, SIV fragment. ≥95% 1590.83 C65H115N21O23S1 Ambient -20°C "Münch J, Sauermann U, Yolamanova M, et al. Effect of semen and seminal amyloid on vaginal transmission of simian immunodeficiency virus. Retrovirology. 2013 Dec 5;10:148. PMID: 24308721.

 

Xu Y, Weatherall C, Bailey M, et al. Simian immunodeficiency virus infects follicular helper CD4 T cells in lymphoid tissues during pathogenic infection of pigtail macaques. J Virol. 2013 Apr;87(7):3760-73. PMID: 23325697.

 

Luciw PA, Shaw KE, Unger RE, et al. Genetic and biological comparisons of pathogenic and nonpathogenic molecular clones of simian immunodeficiency virus (SIVmac). AIDS Res Hum Retroviruses. 1992 Mar;8(3):395-402. PMID: 1571198.

 

Naidu YM, Kestler HW 3rd, Li Y, et al. Characterization of infectious molecular clones of simian immunodeficiency virus (SIVmac) and human immunodeficiency virus type 2: persistent infection of rhesus monkeys with molecularly cloned SIVmac. J Virol. 1988 Dec;62(12):4691-6. PMID: 2846880.

"

LKT S3584 Sivelestat Sodium Tetrahydrate 5 mg 83.7 Neutrophil elastase inhibitor. 201677-61-4 ≥98% 528.51 C20H21N2O7S Na 4H2O CC(C)(C)C(=O)OC1=CC=C(C=C1)S(=O)(=O)NC2=CC=CC=C2C(=O)NCC(=O)[O-].O.O.O.O.[Na+] Ambient Ambient "Aune SE, Yeh ST, Kuppusamy P, et al. Sivelestat attenuates myocardial reperfusion injury during brief low flow postischemic infusion. Oxid Med Cell Longev. 2013;2013:279847. PMID: 23766850.

 

Araki Y, Matsumiya M, Matsuura T, et al. Sivelestat suppresses iNOS gene expression in proinflammatory cytokine-stimulated hepatocytes. Dig Dis Sci. 2011 Jun;56(6):1672-81. PMID: 21221803.

 

Wada Y, Yoshida K, Tsutani Y, et al. Neutrophil elastase induces cell proliferation and migration by the release of TGF-alpha, PDGF and VEGF in esophageal cell lines. Oncol Rep. 2007 Jan;17(1):161-7. PMID: 17143494.

 

Takayama N, Uchida K. Epithelium-dependent and -independent inhibitory effects of sivelestat, a neutrophil elastase inhibitor, on substance P-induced contraction of airway smooth muscle in lipopolysaccharide-treated guinea-pigs. J Smooth Muscle Res. 2005 Oct;41(5):257-70. PMID: 16428865.

" Not dangerous goods.

LKT S3584 Sivelestat Sodium Tetrahydrate 25 mg 326.3 Neutrophil elastase inhibitor. 201677-61-4 ≥98% 528.51 C20H21N2O7S Na 4H2O CC(C)(C)C(=O)OC1=CC=C(C=C1)S(=O)(=O)NC2=CC=CC=C2C(=O)NCC(=O)[O-].O.O.O.O.[Na+] Ambient Ambient "Aune SE, Yeh ST, Kuppusamy P, et al. Sivelestat attenuates myocardial reperfusion injury during brief low flow postischemic infusion. Oxid Med Cell Longev. 2013;2013:279847. PMID: 23766850.

 

Araki Y, Matsumiya M, Matsuura T, et al. Sivelestat suppresses iNOS gene expression in proinflammatory cytokine-stimulated hepatocytes. Dig Dis Sci. 2011 Jun;56(6):1672-81. PMID: 21221803.

 

Wada Y, Yoshida K, Tsutani Y, et al. Neutrophil elastase induces cell proliferation and migration by the release of TGF-alpha, PDGF and VEGF in esophageal cell lines. Oncol Rep. 2007 Jan;17(1):161-7. PMID: 17143494.

 

Takayama N, Uchida K. Epithelium-dependent and -independent inhibitory effects of sivelestat, a neutrophil elastase inhibitor, on substance P-induced contraction of airway smooth muscle in lipopolysaccharide-treated guinea-pigs. J Smooth Muscle Res. 2005 Oct;41(5):257-70. PMID: 16428865.

" Not dangerous goods.

LKT M1876 16-O-Methylcafestol 10 mg 325.9 Diterpene cafestol derivative found in coffee beans. 108214-28-4 ≥98% 330.46 C21H30O3 CC12CCC3=C(C1CCC45C2CCC(C4)C(C5)(CO)OC)C=CO3 Ambient -20°C "Liao XL, Chen XZ, Yu KB, et al. 16-O-Methyl-cafestol. Acta Crystallogr Sect E Struct Rep Online. 2010 Mar 6;66(Pt 4):o760. PMID: 21580605.

 

Mensink RP, Lebbink WJ, Lobbezoo IE, et al. Diterpene composition of oils from Arabica and Robusta coffee beans and their effects on serum lipids in man. J Intern Med. 1995 Jun;237(6):543-50. PMID: 7782725." Not dangerous goods.

LKT M1876 16-O-Methylcafestol 25 mg 651.6 Diterpene cafestol derivative found in coffee beans. 108214-28-4 ≥98% 330.46 C21H30O3 CC12CCC3=C(C1CCC45C2CCC(C4)C(C5)(CO)OC)C=CO3 Ambient -20°C "Liao XL, Chen XZ, Yu KB, et al. 16-O-Methyl-cafestol. Acta Crystallogr Sect E Struct Rep Online. 2010 Mar 6;66(Pt 4):o760. PMID: 21580605.

 

Mensink RP, Lebbink WJ, Lobbezoo IE, et al. Diterpene composition of oils from Arabica and Robusta coffee beans and their effects on serum lipids in man. J Intern Med. 1995 Jun;237(6):543-50. PMID: 7782725." Not dangerous goods.

LKT M1876 16-O-Methylcafestol 100 mg 1737.5 Diterpene cafestol derivative found in coffee beans. 108214-28-4 ≥98% 330.46 C21H30O3 CC12CCC3=C(C1CCC45C2CCC(C4)C(C5)(CO)OC)C=CO3 Ambient -20°C "Liao XL, Chen XZ, Yu KB, et al. 16-O-Methyl-cafestol. Acta Crystallogr Sect E Struct Rep Online. 2010 Mar 6;66(Pt 4):o760. PMID: 21580605.

 

Mensink RP, Lebbink WJ, Lobbezoo IE, et al. Diterpene composition of oils from Arabica and Robusta coffee beans and their effects on serum lipids in man. J Intern Med. 1995 Jun;237(6):543-50. PMID: 7782725." Not dangerous goods.

LKT S3449 Simvastatin 50 mg 146.8 Statin; HMG-CoA reductase inhibitor, potential ATP-sensitive K+ channel activator, L-type Ca2+ channel blocker. 2,2-Dimethylbutanoic acid (1S,3R,7S,8S,8aR)-1,2,3,7,8,8a-hexahydro-3,7-dimethyl-8-[2-[(2R,4R)-tetrahydro-4-hydroxy-6-oxo-2H-pyran-2-yl]ethyl]-1-naphthalenyl ester Synvinolin; MK-733; Denan; Liponorm; Lodales; Simovil; Sinvacor; Sivastin; Zocor; Zocord 79902-63-9 ≥97% 418.57 C25H38O5 CCC(C)(C)C(=O)OC1CC(C=C2C1C(C(C=C2)C)CCC3CC(CC(=O)O3)O)C Ambient Ambient Soluble in DMSO (540 mg/ml); ethanol (160 mg/ml); methanol (200 mg/ml). Insoluble in water. "Zhou J, Li W, Xie Q, et al. Effects of simvastatin on glucose metabolism in mouse MIN6 cells. J Diabetes Res. 2014;2014:376570. PMID: 24995341.

 

Banach M, Czuczwar SJ, Borowicz KK. Statins - are they anticonvulsant? Pharmacol Rep. 2014 Aug;66(4):521-8. PMID: 24948050.

 

Wang Q, Wei X, Gao H, et al. Simvastatin reverses the downregulation of M1/4 receptor binding in 6-hydroxydopamine-induced parkinsonian rats: the association with improvements in long-term memory. Neuroscience. 2014 May 16;267:57-66. PMID: 24613723.

 

Yang N, Cui Y, Tan J, et al. Local injection of a single dose of simvastatin augments osteoporotic bone mass in ovariectomized rats. J Bone Miner Metab. 2014 May;32(3):252-60. PMID: 23934055.

 

Ishikawa S, Hayashi H, Kinoshita K, et al. Statins inhibit tumor progression via an enhancer of zeste homolog 2-mediated epigenetic alteration in colorectal cancer. Int J Cancer. 2013 Dec 17. [Epub ahead of print]. PMID: 24346863.

 

Moraes LA, Vaiyapuri S, Sasikumar P, et al. Antithrombotic actions of statins involve PECAM-1 signaling. Blood. 2013 Oct 31;122(18):3188-96. PMID: 24030383.

 

Liu PY, Liu YW, Lin LJ, et al. Evidence for statin pleiotropy in humans: differential effects of statins and ezetimibe on rho-associated coiled-coil containing protein kinase activity, endothelial function, and inflammation. Circulation. 2009 Jan 6;119(1):131-8. PMID: 19075102.

" None Not dangerous goods.

LKT S3449 Simvastatin 100 mg 251.5 Statin; HMG-CoA reductase inhibitor, potential ATP-sensitive K+ channel activator, L-type Ca2+ channel blocker. 2,2-Dimethylbutanoic acid (1S,3R,7S,8S,8aR)-1,2,3,7,8,8a-hexahydro-3,7-dimethyl-8-[2-[(2R,4R)-tetrahydro-4-hydroxy-6-oxo-2H-pyran-2-yl]ethyl]-1-naphthalenyl ester Synvinolin; MK-733; Denan; Liponorm; Lodales; Simovil; Sinvacor; Sivastin; Zocor; Zocord 79902-63-9 ≥97% 418.57 C25H38O5 CCC(C)(C)C(=O)OC1CC(C=C2C1C(C(C=C2)C)CCC3CC(CC(=O)O3)O)C Ambient Ambient Soluble in DMSO (540 mg/ml); ethanol (160 mg/ml); methanol (200 mg/ml). Insoluble in water. "Zhou J, Li W, Xie Q, et al. Effects of simvastatin on glucose metabolism in mouse MIN6 cells. J Diabetes Res. 2014;2014:376570. PMID: 24995341.

 

Banach M, Czuczwar SJ, Borowicz KK. Statins - are they anticonvulsant? Pharmacol Rep. 2014 Aug;66(4):521-8. PMID: 24948050.

 

Wang Q, Wei X, Gao H, et al. Simvastatin reverses the downregulation of M1/4 receptor binding in 6-hydroxydopamine-induced parkinsonian rats: the association with improvements in long-term memory. Neuroscience. 2014 May 16;267:57-66. PMID: 24613723.

 

Yang N, Cui Y, Tan J, et al. Local injection of a single dose of simvastatin augments osteoporotic bone mass in ovariectomized rats. J Bone Miner Metab. 2014 May;32(3):252-60. PMID: 23934055.

 

Ishikawa S, Hayashi H, Kinoshita K, et al. Statins inhibit tumor progression via an enhancer of zeste homolog 2-mediated epigenetic alteration in colorectal cancer. Int J Cancer. 2013 Dec 17. [Epub ahead of print]. PMID: 24346863.

 

Moraes LA, Vaiyapuri S, Sasikumar P, et al. Antithrombotic actions of statins involve PECAM-1 signaling. Blood. 2013 Oct 31;122(18):3188-96. PMID: 24030383.

 

Liu PY, Liu YW, Lin LJ, et al. Evidence for statin pleiotropy in humans: differential effects of statins and ezetimibe on rho-associated coiled-coil containing protein kinase activity, endothelial function, and inflammation. Circulation. 2009 Jan 6;119(1):131-8. PMID: 19075102.

" None Not dangerous goods.

LKT M1877 Methylprednisolone 100 mg 81 Synthetic steroid; glucocorticoid agonist. (6α,11β)-11,17,21-Trihydroxy-6-methylpregna-1,4- diene-3,20-dione Medrate; Medrol; Medrone; Urbason 83-43-2 ≥96% 374.47 C22H30O5 CC1CC2C3CCC(C3(CC(C2C4(C1=CC(=O)C=C4)C)O)C)(C(=O)CO)O Ambient 4°C Slightly soluble in ethanol (10 mg/mL), dioxane, acetone, or chloroform. Insoluble in water. "Lu YS, Pu LY, Li XC, et al. Methylprednisolone inhibits activated CD4+ T cell survival promoted by toll-like receptor ligands. Hepatobiliary Pancreat Dis Int. 2010 Aug;9(4):376-83. PMID: 20688601.

 

Das A, Banik NL, Ray SK. Methylprednisolone and indomethacin inhibit oxidative stress mediated apoptosis in rat C6 glioblastoma cells. Neurochem Res. 2007 Nov;32(11):1849-56. PMID: 17570061.

 

Sloka JS, Stefanelli M. The mechanism of action of methylprednisolone in the treatment of multiple sclerosis. Mult Scler. 2005 Aug;11(4):425-32. PMID: 16042225.

" None Not dangerous goods.

LKT M1877 Methylprednisolone 500 mg 245.1 Synthetic steroid; glucocorticoid agonist. (6α,11β)-11,17,21-Trihydroxy-6-methylpregna-1,4- diene-3,20-dione Medrate; Medrol; Medrone; Urbason 83-43-2 ≥96% 374.47 C22H30O5 CC1CC2C3CCC(C3(CC(C2C4(C1=CC(=O)C=C4)C)O)C)(C(=O)CO)O Ambient 4°C Slightly soluble in ethanol (10 mg/mL), dioxane, acetone, or chloroform. Insoluble in water. "Lu YS, Pu LY, Li XC, et al. Methylprednisolone inhibits activated CD4+ T cell survival promoted by toll-like receptor ligands. Hepatobiliary Pancreat Dis Int. 2010 Aug;9(4):376-83. PMID: 20688601.

 

Das A, Banik NL, Ray SK. Methylprednisolone and indomethacin inhibit oxidative stress mediated apoptosis in rat C6 glioblastoma cells. Neurochem Res. 2007 Nov;32(11):1849-56. PMID: 17570061.

 

Sloka JS, Stefanelli M. The mechanism of action of methylprednisolone in the treatment of multiple sclerosis. Mult Scler. 2005 Aug;11(4):425-32. PMID: 16042225.

" None Not dangerous goods.

LKT M1877 Methylprednisolone 1 g 418.3 Synthetic steroid; glucocorticoid agonist. (6α,11β)-11,17,21-Trihydroxy-6-methylpregna-1,4- diene-3,20-dione Medrate; Medrol; Medrone; Urbason 83-43-2 ≥96% 374.47 C22H30O5 CC1CC2C3CCC(C3(CC(C2C4(C1=CC(=O)C=C4)C)O)C)(C(=O)CO)O Ambient 4°C Slightly soluble in ethanol (10 mg/mL), dioxane, acetone, or chloroform. Insoluble in water. "Lu YS, Pu LY, Li XC, et al. Methylprednisolone inhibits activated CD4+ T cell survival promoted by toll-like receptor ligands. Hepatobiliary Pancreat Dis Int. 2010 Aug;9(4):376-83. PMID: 20688601.

 

Das A, Banik NL, Ray SK. Methylprednisolone and indomethacin inhibit oxidative stress mediated apoptosis in rat C6 glioblastoma cells. Neurochem Res. 2007 Nov;32(11):1849-56. PMID: 17570061.

 

Sloka JS, Stefanelli M. The mechanism of action of methylprednisolone in the treatment of multiple sclerosis. Mult Scler. 2005 Aug;11(4):425-32. PMID: 16042225.

" None Not dangerous goods.

LKT S3449 Simvastatin 500 mg 611.5 Statin; HMG-CoA reductase inhibitor, potential ATP-sensitive K+ channel activator, L-type Ca2+ channel blocker. 2,2-Dimethylbutanoic acid (1S,3R,7S,8S,8aR)-1,2,3,7,8,8a-hexahydro-3,7-dimethyl-8-[2-[(2R,4R)-tetrahydro-4-hydroxy-6-oxo-2H-pyran-2-yl]ethyl]-1-naphthalenyl ester Synvinolin; MK-733; Denan; Liponorm; Lodales; Simovil; Sinvacor; Sivastin; Zocor; Zocord 79902-63-9 ≥97% 418.57 C25H38O5 CCC(C)(C)C(=O)OC1CC(C=C2C1C(C(C=C2)C)CCC3CC(CC(=O)O3)O)C Ambient Ambient Soluble in DMSO (540 mg/ml); ethanol (160 mg/ml); methanol (200 mg/ml). Insoluble in water. "Zhou J, Li W, Xie Q, et al. Effects of simvastatin on glucose metabolism in mouse MIN6 cells. J Diabetes Res. 2014;2014:376570. PMID: 24995341.

 

Banach M, Czuczwar SJ, Borowicz KK. Statins - are they anticonvulsant? Pharmacol Rep. 2014 Aug;66(4):521-8. PMID: 24948050.

 

Wang Q, Wei X, Gao H, et al. Simvastatin reverses the downregulation of M1/4 receptor binding in 6-hydroxydopamine-induced parkinsonian rats: the association with improvements in long-term memory. Neuroscience. 2014 May 16;267:57-66. PMID: 24613723.

 

Yang N, Cui Y, Tan J, et al. Local injection of a single dose of simvastatin augments osteoporotic bone mass in ovariectomized rats. J Bone Miner Metab. 2014 May;32(3):252-60. PMID: 23934055.

 

Ishikawa S, Hayashi H, Kinoshita K, et al. Statins inhibit tumor progression via an enhancer of zeste homolog 2-mediated epigenetic alteration in colorectal cancer. Int J Cancer. 2013 Dec 17. [Epub ahead of print]. PMID: 24346863.

 

Moraes LA, Vaiyapuri S, Sasikumar P, et al. Antithrombotic actions of statins involve PECAM-1 signaling. Blood. 2013 Oct 31;122(18):3188-96. PMID: 24030383.

 

Liu PY, Liu YW, Lin LJ, et al. Evidence for statin pleiotropy in humans: differential effects of statins and ezetimibe on rho-associated coiled-coil containing protein kinase activity, endothelial function, and inflammation. Circulation. 2009 Jan 6;119(1):131-8. PMID: 19075102.

" None Not dangerous goods.

LKT M1878 16-O-Methylkahweol 5 mg 266.3 Diterpene kahweol derivative found in coffee beans. ≥98% 328.45 C21H28O3 Ambient -20°C Mensink RP, Lebbink WJ, Lobbezoo IE, et al. Diterpene composition of oils from Arabica and Robusta coffee beans and their effects on serum lipids in man. J Intern Med. 1995 Jun;237(6):543-50. PMID: 7782725. Not dangerous goods.

LKT M1878 16-O-Methylkahweol 10 mg 444.4 Diterpene kahweol derivative found in coffee beans. ≥98% 328.45 C21H28O3 Ambient -20°C Mensink RP, Lebbink WJ, Lobbezoo IE, et al. Diterpene composition of oils from Arabica and Robusta coffee beans and their effects on serum lipids in man. J Intern Med. 1995 Jun;237(6):543-50. PMID: 7782725. Not dangerous goods.

LKT M1878 16-O-Methylkahweol 50 mg 1893.6 Diterpene kahweol derivative found in coffee beans. ≥98% 328.45 C21H28O3 Ambient -20°C Mensink RP, Lebbink WJ, Lobbezoo IE, et al. Diterpene composition of oils from Arabica and Robusta coffee beans and their effects on serum lipids in man. J Intern Med. 1995 Jun;237(6):543-50. PMID: 7782725. Not dangerous goods.

LKT M1879 Metoprolol Tartrate 5 g 47.6 β1-adrenergic antagonist. 1-[4-(2-Methoxyethyl)phenoxy]-3-[(1-methylethyl)- amino]-2-propanol tartrate Beloc; Betaloc; Lopressor; Prelis; Seloken; Selopral; Selo-Zok 56392-17-7 ≥98% 684.82 (C15H25NO3)2 C4H6O6 CC(C)NCC(COC1=CC=C(C=C1)CCOC)O.CC(C)NCC(COC1=CC=C(C=C1)CCOC)O.C(C(C(=O)O)O)(C(=O)O)O Metoprolol tartrate is very soluble in water and appears to be very stable in aqueous solution.1,2 Peterson et al1 investigated the stability of metoprolol oral. Ambient Ambient Soluble in water, methanol, or chloroform. "Ulleryd MA, Bernberg E, Yang LJ, et al. Metoprolol Reduces Proinflammatory Cytokines and Atherosclerosis in ApoE(-/-) Mice. Biomed Res Int. 2014;2014:548783. PMID: 25105129.

 

Borowicz KK, Banach M. Antiarrhythmic drugs and epilepsy. Pharmacol Rep. 2014 Aug;66(4):545-51. PMID: 24948053.

 

Stati T, Musumeci M, Maccari S, et al. β-Blockers promote angiogenesis in the mouse aortic ring assay. J Cardiovasc Pharmacol. 2014 Jul;64(1):21-7. PMID: 24621648.

" Not dangerous goods.

LKT M1879 Metoprolol Tartrate 25 g 169.9 β1-adrenergic antagonist. 1-[4-(2-Methoxyethyl)phenoxy]-3-[(1-methylethyl)- amino]-2-propanol tartrate Beloc; Betaloc; Lopressor; Prelis; Seloken; Selopral; Selo-Zok 56392-17-7 ≥98% 684.82 (C15H25NO3)2 C4H6O6 CC(C)NCC(COC1=CC=C(C=C1)CCOC)O.CC(C)NCC(COC1=CC=C(C=C1)CCOC)O.C(C(C(=O)O)O)(C(=O)O)O Metoprolol tartrate is very soluble in water and appears to be very stable in aqueous solution.1,2 Peterson et al1 investigated the stability of metoprolol oral. Ambient Ambient Soluble in water, methanol, or chloroform. "Ulleryd MA, Bernberg E, Yang LJ, et al. Metoprolol Reduces Proinflammatory Cytokines and Atherosclerosis in ApoE(-/-) Mice. Biomed Res Int. 2014;2014:548783. PMID: 25105129.

 

Borowicz KK, Banach M. Antiarrhythmic drugs and epilepsy. Pharmacol Rep. 2014 Aug;66(4):545-51. PMID: 24948053.

 

Stati T, Musumeci M, Maccari S, et al. β-Blockers promote angiogenesis in the mouse aortic ring assay. J Cardiovasc Pharmacol. 2014 Jul;64(1):21-7. PMID: 24621648.

" Not dangerous goods.

LKT M1976 Methimazole 10 g 31.5 Thioamide; thyroid peroxidase inhibitor. 1,3-Dihydro-1-methyl-2H-imidazole-2-thione Basolan; Favistan; Frentirox; Mercazole; Tapazole; Thycapsol; Strumazol 60-56-0 ≥98% 114.17 C4H6N2S CN1C=CNC1=S Ambient Ambient Soluble in water (200 mg/mL), ethanol (200 mg/mL), or chloroform. Slightly soluble in ether or benzene. "Rivkees SA. Pediatric Graves' disease: management in the post-propylthiouracil Era. Int J Pediatr Endocrinol. 2014;2014(1):10. PMID: 25089127.

 

Manna D, Roy G, Mugesh G. Antithyroid drugs and their analogues: synthesis, structure, and mechanism of action. Acc Chem Res. 2013 Nov 19;46(11):2706-15. PMID: 23883148.

 

Crescioli C, Cosmi L, Borgogni E, et al. Methimazole inhibits CXC chemokine ligand 10 secretion in human thyrocytes. J Endocrinol. 2007 Oct;195(1):145-55. PMID: 17911406.

" Xn Not dangerous goods.

LKT M1976 Methimazole 25 g 47.9 Thioamide; thyroid peroxidase inhibitor. 1,3-Dihydro-1-methyl-2H-imidazole-2-thione Basolan; Favistan; Frentirox; Mercazole; Tapazole; Thycapsol; Strumazol 60-56-0 ≥98% 114.17 C4H6N2S CN1C=CNC1=S Ambient Ambient Soluble in water (200 mg/mL), ethanol (200 mg/mL), or chloroform. Slightly soluble in ether or benzene. "Rivkees SA. Pediatric Graves' disease: management in the post-propylthiouracil Era. Int J Pediatr Endocrinol. 2014;2014(1):10. PMID: 25089127.

 

Manna D, Roy G, Mugesh G. Antithyroid drugs and their analogues: synthesis, structure, and mechanism of action. Acc Chem Res. 2013 Nov 19;46(11):2706-15. PMID: 23883148.

 

Crescioli C, Cosmi L, Borgogni E, et al. Methimazole inhibits CXC chemokine ligand 10 secretion in human thyrocytes. J Endocrinol. 2007 Oct;195(1):145-55. PMID: 17911406.

" Xn Not dangerous goods.

LKT M1977 Metronidazole 5 g 43.5 Nitroimidazole; DNA synthesis inhibitor. 1-(2-Hydroxy-1-ethyl)-2-methyl-5-nitroimidazole Arilin; Deflamon; Flagyl; Gineflavir; Klion; MetroGel; Trichazol; Vagilen; Zidoval 443-48-1 ≥98% 171.15 C6H9N3O3 CC1=NC=C(N1CCO)[N+](=O)[O-] In DMSO at +4 for 2 weeks at -80 for 6 months. Ambient Ambient Soluble in water, dilute acids and ethanol. Slightly soluble in DMF. DMSO 34 mg/mL. "Cohen SH, Gerding DN, Johnson S, et al. Clinical practice guidelines for Clostridium difficile infection in adults: 2010 update by the society for healthcare epidemiology of America (SHEA) and the infectious diseases society of America (IDSA). Infect Control Hosp Epidemiol. 2010 May;31(5):431-55. PMID: 20307191.

 

Raether W, Hänel H. Nitroheterocyclic drugs with broad spectrum activity. Parasitol Res. 2003 Jun;90 Supp 1:S19-39. PMID: 12811546.

" Not dangerous goods.

LKT M1977 Metronidazole 25 g 138.1 Nitroimidazole; DNA synthesis inhibitor. 1-(2-Hydroxy-1-ethyl)-2-methyl-5-nitroimidazole Arilin; Deflamon; Flagyl; Gineflavir; Klion; MetroGel; Trichazol; Vagilen; Zidoval 443-48-1 ≥98% 171.15 C6H9N3O3 CC1=NC=C(N1CCO)[N+](=O)[O-] In DMSO at +4 for 2 weeks at -80 for 6 months. Ambient Ambient Soluble in water, dilute acids and ethanol. Slightly soluble in DMF. DMSO 34 mg/mL. "Cohen SH, Gerding DN, Johnson S, et al. Clinical practice guidelines for Clostridium difficile infection in adults: 2010 update by the society for healthcare epidemiology of America (SHEA) and the infectious diseases society of America (IDSA). Infect Control Hosp Epidemiol. 2010 May;31(5):431-55. PMID: 20307191.

 

Raether W, Hänel H. Nitroheterocyclic drugs with broad spectrum activity. Parasitol Res. 2003 Jun;90 Supp 1:S19-39. PMID: 12811546.

" Not dangerous goods.

LKT M1977 Metronidazole 100 g 360.5 Nitroimidazole; DNA synthesis inhibitor. 1-(2-Hydroxy-1-ethyl)-2-methyl-5-nitroimidazole Arilin; Deflamon; Flagyl; Gineflavir; Klion; MetroGel; Trichazol; Vagilen; Zidoval 443-48-1 ≥98% 171.15 C6H9N3O3 CC1=NC=C(N1CCO)[N+](=O)[O-] In DMSO at +4 for 2 weeks at -80 for 6 months. Ambient Ambient Soluble in water, dilute acids and ethanol. Slightly soluble in DMF. DMSO 34 mg/mL. "Cohen SH, Gerding DN, Johnson S, et al. Clinical practice guidelines for Clostridium difficile infection in adults: 2010 update by the society for healthcare epidemiology of America (SHEA) and the infectious diseases society of America (IDSA). Infect Control Hosp Epidemiol. 2010 May;31(5):431-55. PMID: 20307191.

 

Raether W, Hänel H. Nitroheterocyclic drugs with broad spectrum activity. Parasitol Res. 2003 Jun;90 Supp 1:S19-39. PMID: 12811546.

" Not dangerous goods.

LKT M1979 Methyl Salicylate 250 ml 39.8 Ester found in Spiraea, Betula, and Gaultheria; TRPV1 modulator. 2-Hydroxybenzoic acid methyl ester Wintergreen Oil; Betula Oil; Sweet Birch Oil 119-36-8 ≥98% 152.15 C8H8O3 COC(=O)C1=CC=CC=C1O Ambient Ambient Sparingly soluble in water. Soluble in chloroform and ether.  "Tieman D, Zeigler M, Schmelz E, et al. Functional analysis of a tomato salicylic acid methyl transferase and its role in synthesis of the flavor volatile methyl salicylate. Plant J. 2010 Apr 1;62(1):113-23. PMID: 20070566.

 

Ohta T, Imagawa T, Ito S. Involvement of transient receptor potential vanilloid subtype 1 in analgesic action of methylsalicylate. Mol Pharmacol. 2009 Feb;75(2):307-17. PMID: 18987162.

 

James DG, Price TS. Field-testing of methyl salicylate for recruitment and retention of beneficial insects in grapes and hops. J Chem Ecol. 2004 Aug;30(8):1613-28. PMID: 15537163.

 

Mason L, Moore RA, Edwards JE, et al. Systematic review of efficacy of topical rubefacients containing salicylates for the treatment of acute and chronic pain. BMJ. 2004 Apr 24;328(7446):995. PMID: 15033879.

" Xn, Xi Not dangerous goods.

LKT M1979 Methyl Salicylate 500 ml 66 Ester found in Spiraea, Betula, and Gaultheria; TRPV1 modulator. 2-Hydroxybenzoic acid methyl ester Wintergreen Oil; Betula Oil; Sweet Birch Oil 119-36-8 ≥98% 152.15 C8H8O3 COC(=O)C1=CC=CC=C1O Ambient Ambient Sparingly soluble in water. Soluble in chloroform and ether.  "Tieman D, Zeigler M, Schmelz E, et al. Functional analysis of a tomato salicylic acid methyl transferase and its role in synthesis of the flavor volatile methyl salicylate. Plant J. 2010 Apr 1;62(1):113-23. PMID: 20070566.

 

Ohta T, Imagawa T, Ito S. Involvement of transient receptor potential vanilloid subtype 1 in analgesic action of methylsalicylate. Mol Pharmacol. 2009 Feb;75(2):307-17. PMID: 18987162.

 

James DG, Price TS. Field-testing of methyl salicylate for recruitment and retention of beneficial insects in grapes and hops. J Chem Ecol. 2004 Aug;30(8):1613-28. PMID: 15537163.

 

Mason L, Moore RA, Edwards JE, et al. Systematic review of efficacy of topical rubefacients containing salicylates for the treatment of acute and chronic pain. BMJ. 2004 Apr 24;328(7446):995. PMID: 15033879.

" Xn, Xi Not dangerous goods.

LKT M1979 Methyl Salicylate 1 L 110 Ester found in Spiraea, Betula, and Gaultheria; TRPV1 modulator. 2-Hydroxybenzoic acid methyl ester Wintergreen Oil; Betula Oil; Sweet Birch Oil 119-36-8 ≥98% 152.15 C8H8O3 COC(=O)C1=CC=CC=C1O Ambient Ambient Sparingly soluble in water. Soluble in chloroform and ether.  "Tieman D, Zeigler M, Schmelz E, et al. Functional analysis of a tomato salicylic acid methyl transferase and its role in synthesis of the flavor volatile methyl salicylate. Plant J. 2010 Apr 1;62(1):113-23. PMID: 20070566.

 

Ohta T, Imagawa T, Ito S. Involvement of transient receptor potential vanilloid subtype 1 in analgesic action of methylsalicylate. Mol Pharmacol. 2009 Feb;75(2):307-17. PMID: 18987162.

 

James DG, Price TS. Field-testing of methyl salicylate for recruitment and retention of beneficial insects in grapes and hops. J Chem Ecol. 2004 Aug;30(8):1613-28. PMID: 15537163.

 

Mason L, Moore RA, Edwards JE, et al. Systematic review of efficacy of topical rubefacients containing salicylates for the treatment of acute and chronic pain. BMJ. 2004 Apr 24;328(7446):995. PMID: 15033879.

" Xn, Xi Not dangerous goods.

LKT S3351 Sincalide 0.5 mg 281.2 Peptide fragment of CCK; CCK agonist. Cholecystokinin, CCK Octapeptide (26-33); CCK8 25126-32-3 ≥95% 1143.29 C49H62N10O16S3 CSCCC(C(=O)NCC(=O)NC(CC1=CNC2=CC=CC=C21)C(=O)NC(CCSC)C(=O)NC(CC(=O)O)C(=O)NC(CC3=CC=CC=C3)C(=O)N)NC(=O)C(CC4=CC=C(C=C4)OS(=O)(=O)O)NC(=O)C(CC(=O)O)N Ambient -20°C "Zhang LL, Wei XF, Zhang YH, et al. CCK-8S increased the filopodia and spines density in cultured hippocampal neurons of APP/PS1 and wild-type mice. Neurosci Lett. 2013 May 10;542:47-52. PMID: 23541713.

 

Zhang JG, Cong B, Jia XX, et al. Cholecystokinin octapeptide inhibits immunoglobulin G1 production of lipopolysaccharide-activated B cells. Int Immunopharmacol. 2011 Nov;11(11):1685-90. PMID: 21664492.

 

Kang KS, Yahashi S, Azuma M, et al. The anorexigenic effect of cholecystokinin octapeptide in a goldfish model is mediated by the vagal afferent and subsequently through the melanocortin- and corticotropin-releasing hormone-signaling pathways. Peptides. 2010 Nov;31(11):2130-4. PMID: 20688118.

 

Seth H, Gräns A, Axelsson M. Cholecystokinin as a regulator of cardiac function and postprandial gastrointestinal blood flow in rainbow trout (Oncorhynchus mykiss). Am J Physiol Regul Integr Comp Physiol. 2010 May;298(5):R1240-8. PMID: 20164206.

 

Merino B, Cano V, Guzmán R, et al. Leptin-mediated hypothalamic pathway of cholecystokinin (CCK-8) to regulate body weight in free-feeding rats. Endocrinology. 2008 Apr;149(4):1994-2000. PMID: 18096657.

 

Wan S, Coleman FH, Travagli RA. Cholecystokinin-8s excites identified rat pancreatic-projecting vagal motoneurons. Am J Physiol Gastrointest Liver Physiol. 2007 Aug;293(2):G484-92. PMID: 17569742.

 

Porter JR, Sander LD. The effect of cholecystokinin octapeptide on pituitary-adrenal hormone secretion. Regul Pept. 1981 Aug;2(4):245-52. PMID: 6269155.

 

Jensen SL, Holst JJ, Nielsen OV, et al. Effect of sulfation of CCK-8 on its stimulation of the endocrine and exocrine secretion from the isolated perfused porcine pancreas. Digestion. 1981;22(6):305-9. PMID: 6277714.

" Not dangerous goods.

LKT M2076 Metformin Hydrochloride 25 g 50.6 AMPK activator. 1,1-Dimethylbiguanide Hydrochloride Dimethylbiguanide hydrochloride; Imidodicaronimidic diamide; N,N-dimethyl-, monohydrochloride; N,N-Dimethylbiguanide hydrochloride 1115-70-4 ≥98% 165.62 C4H11N5 HCl CN(C)C(=N)N=C(N)N.Cl In DMSO at +4 for 2 weeks at -80 for 6 months. Ambient Ambient 100 mM water, 50 mM DMSO "Fan C, Wang Y, Liu Z, et al. Metformin exerts anticancer effects through the inhibition of the Sonic hedgehog signaling pathway in breast cancer. Int J Mol Med. 2015 May 21. [Epub ahead of print]. PMID: 25999130.

 

Miyoshi H, Kato K, Iwama H, et al. Effect of the anti-diabetic drug metformin in hepatocellular carcinoma in vitro and in vivo. Int J Oncol. 2013 Dec 30. [Epub ahead of print]. PMID: 24378856.

 

Piwkowska A, Rogacka D, Jankowski M, et al. Metformin reduces NAD(P)H oxidase activity in mouse cultured podocytes through purinergic dependent mechanism by increasing extracellular ATP concentration. Acta Biochim Pol. 2013;60(4):607-12. PMID: 24432311.

 

Akinyeke T, Matsumura S, Wang X, et al. Metformin targets c-MYC oncogene to prevent prostate cancer. Carcinogenesis. 2013 Dec;34(12):2823-32. PMID: 24130167.

 

Zhang Y, Guan M, Zheng Z, et al. Effects of metformin on CD133+ colorectal cancer cells in diabetic patients. PLoS One. 2013 Nov 21;8(11):e81264. PMID: 24278407.

 

Shin S, Hyun B, Lee A, et al. Metformin Suppresses MHC-Restricted Antigen Presentation by Inhibiting Co-Stimulatory Factors and MHC Molecules in APCs. Biomol Ther (Seoul). 2013 Jan;21(1):35-41. PMID: 24009856.

 

Chu CA, Wiernsperger N, Muscato N, et al. The acute effect of metformin on glucose production in the conscious dog is primarily attributable to inhibition of glycogenolysis. Metabolism. 2000 Dec;49(12):1619-26. PMID: 11145127.

 

Lin HZ, Yang SQ, Chuckaree C, et al. Metformin reverses fatty liver disease in obese, leptin-deficient mice. Nat Med. 2000 Sep;6(9):998-1003. PMID: 10973319.

 

Minassian C, Tarpin S, Mithieux G. Role of glucose-6 phosphatase, glucokinase, and glucose-6 phosphate in liver insulin resistance and its correction by metformin. Biochem Pharmacol. 1998 Apr 15;55(8):1213-9. PMID: 9719475.

 

Stumvoll M, Nurjhan N, Perriello G, et al. Metabolic effects of metformin in non-insulin-dependent diabetes mellitus. N Engl J Med. 1995 Aug 31;333(9):550-4. PMID: 7623903.

 

Nakamichi N, Shima H, Asano S, et al.  Involvement of carnitine/organic cation transporter OCTN1/SLC22A4 in gastrointestinal absorption of metformin. J Pharm Sci. 2013 Sep;102(9):3407-3417. PMID: 23666872.

" Xn, Xi Not dangerous goods.

LKT M2076 Metformin Hydrochloride 100 g 140.5 AMPK activator. 1,1-Dimethylbiguanide Hydrochloride Dimethylbiguanide hydrochloride; Imidodicaronimidic diamide; N,N-dimethyl-, monohydrochloride; N,N-Dimethylbiguanide hydrochloride 1115-70-4 ≥98% 165.62 C4H11N5 HCl CN(C)C(=N)N=C(N)N.Cl In DMSO at +4 for 2 weeks at -80 for 6 months. Ambient Ambient 100 mM water, 50 mM DMSO "Fan C, Wang Y, Liu Z, et al. Metformin exerts anticancer effects through the inhibition of the Sonic hedgehog signaling pathway in breast cancer. Int J Mol Med. 2015 May 21. [Epub ahead of print]. PMID: 25999130.

 

Miyoshi H, Kato K, Iwama H, et al. Effect of the anti-diabetic drug metformin in hepatocellular carcinoma in vitro and in vivo. Int J Oncol. 2013 Dec 30. [Epub ahead of print]. PMID: 24378856.

 

Piwkowska A, Rogacka D, Jankowski M, et al. Metformin reduces NAD(P)H oxidase activity in mouse cultured podocytes through purinergic dependent mechanism by increasing extracellular ATP concentration. Acta Biochim Pol. 2013;60(4):607-12. PMID: 24432311.

 

Akinyeke T, Matsumura S, Wang X, et al. Metformin targets c-MYC oncogene to prevent prostate cancer. Carcinogenesis. 2013 Dec;34(12):2823-32. PMID: 24130167.

 

Zhang Y, Guan M, Zheng Z, et al. Effects of metformin on CD133+ colorectal cancer cells in diabetic patients. PLoS One. 2013 Nov 21;8(11):e81264. PMID: 24278407.

 

Shin S, Hyun B, Lee A, et al. Metformin Suppresses MHC-Restricted Antigen Presentation by Inhibiting Co-Stimulatory Factors and MHC Molecules in APCs. Biomol Ther (Seoul). 2013 Jan;21(1):35-41. PMID: 24009856.

 

Chu CA, Wiernsperger N, Muscato N, et al. The acute effect of metformin on glucose production in the conscious dog is primarily attributable to inhibition of glycogenolysis. Metabolism. 2000 Dec;49(12):1619-26. PMID: 11145127.

 

Lin HZ, Yang SQ, Chuckaree C, et al. Metformin reverses fatty liver disease in obese, leptin-deficient mice. Nat Med. 2000 Sep;6(9):998-1003. PMID: 10973319.

 

Minassian C, Tarpin S, Mithieux G. Role of glucose-6 phosphatase, glucokinase, and glucose-6 phosphate in liver insulin resistance and its correction by metformin. Biochem Pharmacol. 1998 Apr 15;55(8):1213-9. PMID: 9719475.

 

Stumvoll M, Nurjhan N, Perriello G, et al. Metabolic effects of metformin in non-insulin-dependent diabetes mellitus. N Engl J Med. 1995 Aug 31;333(9):550-4. PMID: 7623903.

 

Nakamichi N, Shima H, Asano S, et al.  Involvement of carnitine/organic cation transporter OCTN1/SLC22A4 in gastrointestinal absorption of metformin. J Pharm Sci. 2013 Sep;102(9):3407-3417. PMID: 23666872.

" Xn, Xi Not dangerous goods.

LKT S3351 Sincalide 1 mg 421.8 Peptide fragment of CCK; CCK agonist. Cholecystokinin, CCK Octapeptide (26-33); CCK8 25126-32-3 ≥95% 1143.29 C49H62N10O16S3 CSCCC(C(=O)NCC(=O)NC(CC1=CNC2=CC=CC=C21)C(=O)NC(CCSC)C(=O)NC(CC(=O)O)C(=O)NC(CC3=CC=CC=C3)C(=O)N)NC(=O)C(CC4=CC=C(C=C4)OS(=O)(=O)O)NC(=O)C(CC(=O)O)N Ambient -20°C "Zhang LL, Wei XF, Zhang YH, et al. CCK-8S increased the filopodia and spines density in cultured hippocampal neurons of APP/PS1 and wild-type mice. Neurosci Lett. 2013 May 10;542:47-52. PMID: 23541713.

 

Zhang JG, Cong B, Jia XX, et al. Cholecystokinin octapeptide inhibits immunoglobulin G1 production of lipopolysaccharide-activated B cells. Int Immunopharmacol. 2011 Nov;11(11):1685-90. PMID: 21664492.

 

Kang KS, Yahashi S, Azuma M, et al. The anorexigenic effect of cholecystokinin octapeptide in a goldfish model is mediated by the vagal afferent and subsequently through the melanocortin- and corticotropin-releasing hormone-signaling pathways. Peptides. 2010 Nov;31(11):2130-4. PMID: 20688118.

 

Seth H, Gräns A, Axelsson M. Cholecystokinin as a regulator of cardiac function and postprandial gastrointestinal blood flow in rainbow trout (Oncorhynchus mykiss). Am J Physiol Regul Integr Comp Physiol. 2010 May;298(5):R1240-8. PMID: 20164206.

 

Merino B, Cano V, Guzmán R, et al. Leptin-mediated hypothalamic pathway of cholecystokinin (CCK-8) to regulate body weight in free-feeding rats. Endocrinology. 2008 Apr;149(4):1994-2000. PMID: 18096657.

 

Wan S, Coleman FH, Travagli RA. Cholecystokinin-8s excites identified rat pancreatic-projecting vagal motoneurons. Am J Physiol Gastrointest Liver Physiol. 2007 Aug;293(2):G484-92. PMID: 17569742.

 

Porter JR, Sander LD. The effect of cholecystokinin octapeptide on pituitary-adrenal hormone secretion. Regul Pept. 1981 Aug;2(4):245-52. PMID: 6269155.

 

Jensen SL, Holst JJ, Nielsen OV, et al. Effect of sulfation of CCK-8 on its stimulation of the endocrine and exocrine secretion from the isolated perfused porcine pancreas. Digestion. 1981;22(6):305-9. PMID: 6277714.

" Not dangerous goods.

LKT S3345 Silymarin 10 g 40.6 Flavonolignan mixture found in Silybum (milk thistle) seeds. Apihepar; Laragon; Legalon; Pluropon; Silarine; Silliver 65666-07-1 ≥70% 482.44 C25H22O10 COC1=C(C=CC(=C1)C2C(OC3=C(O2)C=C(C=C3)C4C(C(=O)C5=C(C=C(C=C5O4)O)O)O)CO)O Protect from light. Ambient 4°C Soluble in DMSO or ethanol. "Atawia RT, Mosli HH, Tadros MG, et al. Modulatory effect of silymarin on inflammatory mediators in experimentally induced benign prostatic hyperplasia: emphasis on PTEN, HIF-1α, and NF-κB. Naunyn Schmiedebergs Arch Pharmacol. 2014 Aug 28. [Epub ahead of print]. PMID: 25164963

 

Clichici S, Olteanu D, Nagy AL, et al. Silymarin Inhibits the Progression of Fibrosis in the Early Stages of Liver Injury in CCl4-Treated Rats. J Med Food. 2014 Aug 18. [Epub ahead of print]. PMID: 25133972.

 

Borah A, Paul R, Choudhury S, et al. Neuroprotective potential of silymarin against CNS disorders: insight into the pathways and molecular mechanisms of action. CNS Neurosci Ther. 2013 Nov;19(11):847-53. PMID: 24118806.

 

Su CH, Chen LJ, Liao JF, et al. Increase of phosphatase and tensin homolog by silymarin to inhibit human pharynx squamous cancer. J Med Food. 2013 Sep;16(9):778-84. PMID: 23909904.

 

Kwon do Y, Jung YS, Kim SJ, et al. Alterations in sulfur amino acid metabolism in mice treated with silymarin: a novel mechanism of its action involved in enhancement of the antioxidant defense in liver. Planta Med. 2013 Aug;79(12):997-1002. PMID: 23807810.

 

Gharagozloo M, Javid EN, Rezaei A, et al. Silymarin inhibits cell cycle progression and mTOR activity in activated human T cells: therapeutic implications for autoimmune diseases. Basic Clin Pharmacol Toxicol. 2013 Apr;112(4):251-6. PMID: 23121838.

 

Faezizadeh Z, Mesbah-Namin SA, Allameh A. The effect of silymarin on telomerase activity in the human leukemia cell line K562. Planta Med. 2012 Jun;78(9):899-902. PMID: 22532022.

 

Song JH, Choi HJ. Silymarin efficacy against influenza A virus replication. Phytomedicine. 2011 Jul 15;18(10):832-5. PMID: 21377857.

 

Murata N, Murakami K, Ozawa Y, et al. Silymarin attenuated the amyloid beta plaque burden and improved behavorial abnormalities in an Alzheimer’s disease mouse model. Biosci Biotechnol Biochem. 2010;74(11):2299-2306. PMID: 21071836.

" None Not dangerous goods.

LKT S3345 Silymarin 50 g 126.5 Flavonolignan mixture found in Silybum (milk thistle) seeds. Apihepar; Laragon; Legalon; Pluropon; Silarine; Silliver 65666-07-1 ≥70% 482.44 C25H22O10 COC1=C(C=CC(=C1)C2C(OC3=C(O2)C=C(C=C3)C4C(C(=O)C5=C(C=C(C=C5O4)O)O)O)CO)O Protect from light. Ambient 4°C Soluble in DMSO or ethanol. "Atawia RT, Mosli HH, Tadros MG, et al. Modulatory effect of silymarin on inflammatory mediators in experimentally induced benign prostatic hyperplasia: emphasis on PTEN, HIF-1α, and NF-κB. Naunyn Schmiedebergs Arch Pharmacol. 2014 Aug 28. [Epub ahead of print]. PMID: 25164963

 

Clichici S, Olteanu D, Nagy AL, et al. Silymarin Inhibits the Progression of Fibrosis in the Early Stages of Liver Injury in CCl4-Treated Rats. J Med Food. 2014 Aug 18. [Epub ahead of print]. PMID: 25133972.

 

Borah A, Paul R, Choudhury S, et al. Neuroprotective potential of silymarin against CNS disorders: insight into the pathways and molecular mechanisms of action. CNS Neurosci Ther. 2013 Nov;19(11):847-53. PMID: 24118806.

 

Su CH, Chen LJ, Liao JF, et al. Increase of phosphatase and tensin homolog by silymarin to inhibit human pharynx squamous cancer. J Med Food. 2013 Sep;16(9):778-84. PMID: 23909904.

 

Kwon do Y, Jung YS, Kim SJ, et al. Alterations in sulfur amino acid metabolism in mice treated with silymarin: a novel mechanism of its action involved in enhancement of the antioxidant defense in liver. Planta Med. 2013 Aug;79(12):997-1002. PMID: 23807810.

 

Gharagozloo M, Javid EN, Rezaei A, et al. Silymarin inhibits cell cycle progression and mTOR activity in activated human T cells: therapeutic implications for autoimmune diseases. Basic Clin Pharmacol Toxicol. 2013 Apr;112(4):251-6. PMID: 23121838.

 

Faezizadeh Z, Mesbah-Namin SA, Allameh A. The effect of silymarin on telomerase activity in the human leukemia cell line K562. Planta Med. 2012 Jun;78(9):899-902. PMID: 22532022.

 

Song JH, Choi HJ. Silymarin efficacy against influenza A virus replication. Phytomedicine. 2011 Jul 15;18(10):832-5. PMID: 21377857.

 

Murata N, Murakami K, Ozawa Y, et al. Silymarin attenuated the amyloid beta plaque burden and improved behavorial abnormalities in an Alzheimer’s disease mouse model. Biosci Biotechnol Biochem. 2010;74(11):2299-2306. PMID: 21071836.

" None Not dangerous goods.

LKT M2460 Matrix GLa Protein - pNa 1 mg 90.1 Peptide; vascular calcification inhibitor. MGP-pNa ≥95% 423.4 C18H25N5O5S Ambient -20°C "McCarty MF, DiNicolantonio JJ. The molecular biology and pathophysiology of vascular calcification. Postgrad Med. 2014 Mar;126(2):54-64. PMID: 24685968.

 

Schurgers LJ, Uitto J, Reutelingsperger CP. Vitamin K-dependent carboxylation of matrix Gla-protein: a crucial switch to control ectopic mineralization. Trends Mol Med. 2013 Apr;19(4):217-26. PMID: 23375872.

"

LKT M2460 Matrix GLa Protein - pNa 10 mg 300.1 Peptide; vascular calcification inhibitor. MGP-pNa ≥95% 423.4 C18H25N5O5S Ambient -20°C "McCarty MF, DiNicolantonio JJ. The molecular biology and pathophysiology of vascular calcification. Postgrad Med. 2014 Mar;126(2):54-64. PMID: 24685968.

 

Schurgers LJ, Uitto J, Reutelingsperger CP. Vitamin K-dependent carboxylation of matrix Gla-protein: a crucial switch to control ectopic mineralization. Trends Mol Med. 2013 Apr;19(4):217-26. PMID: 23375872.

"

LKT M3219 Tyr-MIF-1 5 mg 240.1 Neuropeptide; μOR antagonist. (Tyr0)-Melanocyte-stimulating hormone-release inhibiting factor; MIF-1 77133-61-0 ≥95% 447.54 C22H33N5O5 CC(C)CC(C(=O)NCC(=O)N)NC(=O)C1CCCN1C(=O)C(CC2=CC=C(C=C2)O)N Ambient -20°C "Pan W, Kastin AJ. From MIF-1 to endomorphin: the Tyr-MIF-1 family of peptides. Peptides. 2007 Dec;28(12):2411-34. PMID: 17988762.

 

Bocheva A, Dzambazova-Maximova E. Antiopioid properties of the TYR-MIF-1 family. Methods Find Exp Clin Pharmacol. 2004 Nov;26(9):673-7. PMID: 15632952.

 

Zamfirova R, Bocheva A, Todorov S. Involvement of H2-receptors in the mechanism of analgesic action of Tyr-MIF-1. Arch Physiol Biochem. 2003 Dec;111(5):443-7. PMID: 16026032.

 

Million M, Fioramonti J, Bueno L. Central administration of Tyr-MIF-1 stimulates gastrointestinal motility in rats: evidence for the involvement of dopamine, sigma and CCK receptors. Neuropeptides. 1994 Feb;26(2):77-85. PMID: 7909585.

"

LKT M3219 Tyr-MIF-1 10 mg 407.9 Neuropeptide; μOR antagonist. (Tyr0)-Melanocyte-stimulating hormone-release inhibiting factor; MIF-1 77133-61-0 ≥95% 447.54 C22H33N5O5 CC(C)CC(C(=O)NCC(=O)N)NC(=O)C1CCCN1C(=O)C(CC2=CC=C(C=C2)O)N Ambient -20°C "Pan W, Kastin AJ. From MIF-1 to endomorphin: the Tyr-MIF-1 family of peptides. Peptides. 2007 Dec;28(12):2411-34. PMID: 17988762.

 

Bocheva A, Dzambazova-Maximova E. Antiopioid properties of the TYR-MIF-1 family. Methods Find Exp Clin Pharmacol. 2004 Nov;26(9):673-7. PMID: 15632952.

 

Zamfirova R, Bocheva A, Todorov S. Involvement of H2-receptors in the mechanism of analgesic action of Tyr-MIF-1. Arch Physiol Biochem. 2003 Dec;111(5):443-7. PMID: 16026032.

 

Million M, Fioramonti J, Bueno L. Central administration of Tyr-MIF-1 stimulates gastrointestinal motility in rats: evidence for the involvement of dopamine, sigma and CCK receptors. Neuropeptides. 1994 Feb;26(2):77-85. PMID: 7909585.

"

LKT M3219 Tyr-MIF-1 25 mg 720.2 Neuropeptide; μOR antagonist. (Tyr0)-Melanocyte-stimulating hormone-release inhibiting factor; MIF-1 77133-61-0 ≥95% 447.54 C22H33N5O5 CC(C)CC(C(=O)NCC(=O)N)NC(=O)C1CCCN1C(=O)C(CC2=CC=C(C=C2)O)N Ambient -20°C "Pan W, Kastin AJ. From MIF-1 to endomorphin: the Tyr-MIF-1 family of peptides. Peptides. 2007 Dec;28(12):2411-34. PMID: 17988762.

 

Bocheva A, Dzambazova-Maximova E. Antiopioid properties of the TYR-MIF-1 family. Methods Find Exp Clin Pharmacol. 2004 Nov;26(9):673-7. PMID: 15632952.

 

Zamfirova R, Bocheva A, Todorov S. Involvement of H2-receptors in the mechanism of analgesic action of Tyr-MIF-1. Arch Physiol Biochem. 2003 Dec;111(5):443-7. PMID: 16026032.

 

Million M, Fioramonti J, Bueno L. Central administration of Tyr-MIF-1 stimulates gastrointestinal motility in rats: evidence for the involvement of dopamine, sigma and CCK receptors. Neuropeptides. 1994 Feb;26(2):77-85. PMID: 7909585.

"

LKT M3220 Tyr-W-MIF-1 5 mg 240.1 Neuropeptide; μOR antagonist. (Tyr0, Trp2)-Melanocyte-stimulating hormone-release inhibiting factor 144450-13-5 ≥95% 520.59 C27H32N6O5 C1CC(N(C1)C(=O)C(CC2=CC=C(C=C2)O)N)C(=O)NC(CC3=CNC4=CC=CC=C43)C(=O)NCC(=O)N Ambient -20°C "Mizoguchi H, Takagi H, Watanabe C, et al. Involvement of multiple μ-opioid receptor subtypes on the presynaptic or postsynaptic inhibition of spinal pain transmission. Peptides. 2013 Oct 25. pii: S0196-9781(13)00344-6. PMID: 24512946.

 

Bocheva A, Dzambazova E, Hadjiolova R, et al. Effect of Tyr-MIF-1 peptides on blood ACTH and corticosterone concentration induced by three experimental models of stress. Auton Autacoid Pharmacol. 2008 Oct;28(4):117-23. PMID: 18798907.

 

Bocheva A, Dzambazova-Maximova E. Antiopioid properties of the TYR-MIF-1 family. Methods Find Exp Clin Pharmacol. 2004 Nov;26(9):673-7. PMID: 15632952.

 

Nores WL, Olson RD, Olson GA, et al. Tyr-W-MIF-1-induced conditioned place preference. Peptides. 1999;20(4):479-84. PMID: 10458518.

"

LKT M3220 Tyr-W-MIF-1 10 mg 407.9 Neuropeptide; μOR antagonist. (Tyr0, Trp2)-Melanocyte-stimulating hormone-release inhibiting factor 144450-13-5 ≥95% 520.59 C27H32N6O5 C1CC(N(C1)C(=O)C(CC2=CC=C(C=C2)O)N)C(=O)NC(CC3=CNC4=CC=CC=C43)C(=O)NCC(=O)N Ambient -20°C "Mizoguchi H, Takagi H, Watanabe C, et al. Involvement of multiple μ-opioid receptor subtypes on the presynaptic or postsynaptic inhibition of spinal pain transmission. Peptides. 2013 Oct 25. pii: S0196-9781(13)00344-6. PMID: 24512946.

 

Bocheva A, Dzambazova E, Hadjiolova R, et al. Effect of Tyr-MIF-1 peptides on blood ACTH and corticosterone concentration induced by three experimental models of stress. Auton Autacoid Pharmacol. 2008 Oct;28(4):117-23. PMID: 18798907.

 

Bocheva A, Dzambazova-Maximova E. Antiopioid properties of the TYR-MIF-1 family. Methods Find Exp Clin Pharmacol. 2004 Nov;26(9):673-7. PMID: 15632952.

 

Nores WL, Olson RD, Olson GA, et al. Tyr-W-MIF-1-induced conditioned place preference. Peptides. 1999;20(4):479-84. PMID: 10458518.

"

LKT M3220 Tyr-W-MIF-1 25 mg 720.2 Neuropeptide; μOR antagonist. (Tyr0, Trp2)-Melanocyte-stimulating hormone-release inhibiting factor 144450-13-5 ≥95% 520.59 C27H32N6O5 C1CC(N(C1)C(=O)C(CC2=CC=C(C=C2)O)N)C(=O)NC(CC3=CNC4=CC=CC=C43)C(=O)NCC(=O)N Ambient -20°C "Mizoguchi H, Takagi H, Watanabe C, et al. Involvement of multiple μ-opioid receptor subtypes on the presynaptic or postsynaptic inhibition of spinal pain transmission. Peptides. 2013 Oct 25. pii: S0196-9781(13)00344-6. PMID: 24512946.

 

Bocheva A, Dzambazova E, Hadjiolova R, et al. Effect of Tyr-MIF-1 peptides on blood ACTH and corticosterone concentration induced by three experimental models of stress. Auton Autacoid Pharmacol. 2008 Oct;28(4):117-23. PMID: 18798907.

 

Bocheva A, Dzambazova-Maximova E. Antiopioid properties of the TYR-MIF-1 family. Methods Find Exp Clin Pharmacol. 2004 Nov;26(9):673-7. PMID: 15632952.

 

Nores WL, Olson RD, Olson GA, et al. Tyr-W-MIF-1-induced conditioned place preference. Peptides. 1999;20(4):479-84. PMID: 10458518.

"

LKT S3343 Silybin 500 mg 27.2 Flavonoid originally found in Silybum (milk thistle) seeds. (2R,3R)-2-[(2R,3R)-2,3-Dihydro-3-(4-hydroxy-3- methoxyphenyl)-2-(hydroxymethyl)-1,4-benzodioxin- 6-yl]-2,3-dihydro-3,5,7-trihydroxy-4H-1-benzopyran- 4-one AND (2R,3R)-2-[(2S,3S)-2,3-Dihydro-3-(4-hydroxy-3- methoxyphenyl)-2-(hydroxymethyl)-1,4-benzodioxin- 6-yl]-2,3-dihydro-3,5,7-trihydroxy-4H-1-benzopyran- 4-one Silibinin; Silybum substance E6; Silymarin I 22888-70-6 ≥97% 482.44 C25H22O10 COC1=C(C=CC(=C1)C2C(OC3=C(O2)C=C(C=C3)C4C(C(=O)C5=C(C=C(C=C5O4)O)O)O)CO)O Ambient -20°C Soluble in acetone, ethyl acetate, methanol or ethanol. Practically insoluble in water. "Bousserouel S, Bour G, Kauntz H, et al. Silibinin inhibits tumor growth in a murine orthotopic hepatocarcinoma model and activates the TRAIL apoptotic signaling pathway. Anticancer Res. 2012 Jul;32(7):2455-62. PMID: 22753701.

 

Wang Q, Liu M, Liu WW, et al. In vivo recovery effect of silibinin treatment on streptozotocin-induced diabetic mice is associated with the modulations of Sirt-1 expression and autophagy in pancreatic β-cell. J Asian Nat Prod Res. 2012;14(5):413-23. PMID: 22423887.

 

Au AY, Hasenwinkel JM, Frondoza CG. Silybin inhibits interleukin-1β-induced production of pro-inflammatory mediators in canine hepatocyte cultures. J Vet Pharmacol Ther. 2011 Apr;34(2):120-9. PMID: 21395602.

 

Gu M, Singh RP, Dhanalakshmi S, et al. Silibinin inhibits inflammatory and angiogenic attributes in photocarcinogenesis in SKH-1 hairless mice. Cancer Res. 2007 Apr 1;67(7):3483-91. PMID: 17409458.

 

Lee MH, Huang Z, Kim DJ, et al. Direct targeting of MEK1/2 and RSK2 by silybin induces cell-cycle arrest and inhibits melanoma cell growth. Cancer Prev Res (Phila). 2013 May;6(5):455-465. PMID: 23447564.

" Xi Not dangerous goods.

LKT M3309 Miconazole 1 g 44.6 Imidazole; 14-α demethylase inhibitor, potential glucocorticoid antagonist. 1-[2-(2,4-Dichlorophenyl)-2-[(2,4-dichlorophenyl)- methoxy]ethyl]-1H-imidazole Monistat IV  22916-47-8 ≥98% 416.14 C18H14Cl4N2O C1=CC(=C(C=C1Cl)Cl)COC(CN2C=CN=C2)C3=C(C=C(C=C3)Cl)Cl Ambient Ambient Practically insoluble in water. Soluble in ethanol (105 mg/mL), methanol (66 mg/mL) "Park JY, Jung HJ, Seo I, et al. Translational suppression of HIF-1α by miconazole through the mTOR signaling pathway. Cell Oncol (Dordr). 2014 Jul 29. [Epub ahead of print]. PMID: 25070654.

 

Niimi M, Firth NA, Cannon RD. Antifungal drug resistance of oral fungi. Odontology. 2010 Feb;98(1):15-25. PMID: 20155503.

 

Duret C, Daujat-Chavanieu M, Pascussi JM, et al. Ketoconazole and miconazole are antagonists of the human glucocorticoid receptor: consequences on the expression and function of the constitutive androstane receptor and the pregnane X receptor. Mol Pharmacol. 2006 Jul;70(1):329-39. PMID: 16608920.

 

Tatsumi Y, Nagashima M, Shibanushi T, et al. Mechanism of action of efinaconazole, a novel triazole antifungal agent. Antimicrob Agents Chemother. 2013 May;57(5):2405-2409. PMID: 23459486.

" Not dangerous goods.

LKT M3309 Miconazole 5 g 155.1 Imidazole; 14-α demethylase inhibitor, potential glucocorticoid antagonist. 1-[2-(2,4-Dichlorophenyl)-2-[(2,4-dichlorophenyl)- methoxy]ethyl]-1H-imidazole Monistat IV  22916-47-8 ≥98% 416.14 C18H14Cl4N2O C1=CC(=C(C=C1Cl)Cl)COC(CN2C=CN=C2)C3=C(C=C(C=C3)Cl)Cl Ambient Ambient Practically insoluble in water. Soluble in ethanol (105 mg/mL), methanol (66 mg/mL) "Park JY, Jung HJ, Seo I, et al. Translational suppression of HIF-1α by miconazole through the mTOR signaling pathway. Cell Oncol (Dordr). 2014 Jul 29. [Epub ahead of print]. PMID: 25070654.

 

Niimi M, Firth NA, Cannon RD. Antifungal drug resistance of oral fungi. Odontology. 2010 Feb;98(1):15-25. PMID: 20155503.

 

Duret C, Daujat-Chavanieu M, Pascussi JM, et al. Ketoconazole and miconazole are antagonists of the human glucocorticoid receptor: consequences on the expression and function of the constitutive androstane receptor and the pregnane X receptor. Mol Pharmacol. 2006 Jul;70(1):329-39. PMID: 16608920.

 

Tatsumi Y, Nagashima M, Shibanushi T, et al. Mechanism of action of efinaconazole, a novel triazole antifungal agent. Antimicrob Agents Chemother. 2013 May;57(5):2405-2409. PMID: 23459486.

" Not dangerous goods.

LKT S3343 Silybin 1 g 33.9 Flavonoid originally found in Silybum (milk thistle) seeds. (2R,3R)-2-[(2R,3R)-2,3-Dihydro-3-(4-hydroxy-3- methoxyphenyl)-2-(hydroxymethyl)-1,4-benzodioxin- 6-yl]-2,3-dihydro-3,5,7-trihydroxy-4H-1-benzopyran- 4-one AND (2R,3R)-2-[(2S,3S)-2,3-Dihydro-3-(4-hydroxy-3- methoxyphenyl)-2-(hydroxymethyl)-1,4-benzodioxin- 6-yl]-2,3-dihydro-3,5,7-trihydroxy-4H-1-benzopyran- 4-one Silibinin; Silybum substance E6; Silymarin I 22888-70-6 ≥97% 482.44 C25H22O10 COC1=C(C=CC(=C1)C2C(OC3=C(O2)C=C(C=C3)C4C(C(=O)C5=C(C=C(C=C5O4)O)O)O)CO)O Ambient -20°C Soluble in acetone, ethyl acetate, methanol or ethanol. Practically insoluble in water. "Bousserouel S, Bour G, Kauntz H, et al. Silibinin inhibits tumor growth in a murine orthotopic hepatocarcinoma model and activates the TRAIL apoptotic signaling pathway. Anticancer Res. 2012 Jul;32(7):2455-62. PMID: 22753701.

 

Wang Q, Liu M, Liu WW, et al. In vivo recovery effect of silibinin treatment on streptozotocin-induced diabetic mice is associated with the modulations of Sirt-1 expression and autophagy in pancreatic β-cell. J Asian Nat Prod Res. 2012;14(5):413-23. PMID: 22423887.

 

Au AY, Hasenwinkel JM, Frondoza CG. Silybin inhibits interleukin-1β-induced production of pro-inflammatory mediators in canine hepatocyte cultures. J Vet Pharmacol Ther. 2011 Apr;34(2):120-9. PMID: 21395602.

 

Gu M, Singh RP, Dhanalakshmi S, et al. Silibinin inhibits inflammatory and angiogenic attributes in photocarcinogenesis in SKH-1 hairless mice. Cancer Res. 2007 Apr 1;67(7):3483-91. PMID: 17409458.

 

Lee MH, Huang Z, Kim DJ, et al. Direct targeting of MEK1/2 and RSK2 by silybin induces cell-cycle arrest and inhibits melanoma cell growth. Cancer Prev Res (Phila). 2013 May;6(5):455-465. PMID: 23447564.

" Xi Not dangerous goods.

LKT M3309 Miconazole 25 g 498.4 Imidazole; 14-α demethylase inhibitor, potential glucocorticoid antagonist. 1-[2-(2,4-Dichlorophenyl)-2-[(2,4-dichlorophenyl)- methoxy]ethyl]-1H-imidazole Monistat IV  22916-47-8 ≥98% 416.14 C18H14Cl4N2O C1=CC(=C(C=C1Cl)Cl)COC(CN2C=CN=C2)C3=C(C=C(C=C3)Cl)Cl Ambient Ambient Practically insoluble in water. Soluble in ethanol (105 mg/mL), methanol (66 mg/mL) "Park JY, Jung HJ, Seo I, et al. Translational suppression of HIF-1α by miconazole through the mTOR signaling pathway. Cell Oncol (Dordr). 2014 Jul 29. [Epub ahead of print]. PMID: 25070654.

 

Niimi M, Firth NA, Cannon RD. Antifungal drug resistance of oral fungi. Odontology. 2010 Feb;98(1):15-25. PMID: 20155503.

 

Duret C, Daujat-Chavanieu M, Pascussi JM, et al. Ketoconazole and miconazole are antagonists of the human glucocorticoid receptor: consequences on the expression and function of the constitutive androstane receptor and the pregnane X receptor. Mol Pharmacol. 2006 Jul;70(1):329-39. PMID: 16608920.

 

Tatsumi Y, Nagashima M, Shibanushi T, et al. Mechanism of action of efinaconazole, a novel triazole antifungal agent. Antimicrob Agents Chemother. 2013 May;57(5):2405-2409. PMID: 23459486.

" Not dangerous goods.

LKT S3343 Silybin 5 g 101.9 Flavonoid originally found in Silybum (milk thistle) seeds. (2R,3R)-2-[(2R,3R)-2,3-Dihydro-3-(4-hydroxy-3- methoxyphenyl)-2-(hydroxymethyl)-1,4-benzodioxin- 6-yl]-2,3-dihydro-3,5,7-trihydroxy-4H-1-benzopyran- 4-one AND (2R,3R)-2-[(2S,3S)-2,3-Dihydro-3-(4-hydroxy-3- methoxyphenyl)-2-(hydroxymethyl)-1,4-benzodioxin- 6-yl]-2,3-dihydro-3,5,7-trihydroxy-4H-1-benzopyran- 4-one Silibinin; Silybum substance E6; Silymarin I 22888-70-6 ≥97% 482.44 C25H22O10 COC1=C(C=CC(=C1)C2C(OC3=C(O2)C=C(C=C3)C4C(C(=O)C5=C(C=C(C=C5O4)O)O)O)CO)O Ambient -20°C Soluble in acetone, ethyl acetate, methanol or ethanol. Practically insoluble in water. "Bousserouel S, Bour G, Kauntz H, et al. Silibinin inhibits tumor growth in a murine orthotopic hepatocarcinoma model and activates the TRAIL apoptotic signaling pathway. Anticancer Res. 2012 Jul;32(7):2455-62. PMID: 22753701.

 

Wang Q, Liu M, Liu WW, et al. In vivo recovery effect of silibinin treatment on streptozotocin-induced diabetic mice is associated with the modulations of Sirt-1 expression and autophagy in pancreatic β-cell. J Asian Nat Prod Res. 2012;14(5):413-23. PMID: 22423887.

 

Au AY, Hasenwinkel JM, Frondoza CG. Silybin inhibits interleukin-1β-induced production of pro-inflammatory mediators in canine hepatocyte cultures. J Vet Pharmacol Ther. 2011 Apr;34(2):120-9. PMID: 21395602.

 

Gu M, Singh RP, Dhanalakshmi S, et al. Silibinin inhibits inflammatory and angiogenic attributes in photocarcinogenesis in SKH-1 hairless mice. Cancer Res. 2007 Apr 1;67(7):3483-91. PMID: 17409458.

 

Lee MH, Huang Z, Kim DJ, et al. Direct targeting of MEK1/2 and RSK2 by silybin induces cell-cycle arrest and inhibits melanoma cell growth. Cancer Prev Res (Phila). 2013 May;6(5):455-465. PMID: 23447564.

" Xi Not dangerous goods.

LKT M3310 Miconazole Nitrate 1 g 43.5 Imidazole; 14-α demethylase inhibitor, potential glucocorticoid antagonist. 1-[2-(2,4-Dichlorophenyl)-2-[(2,4-dichlorophenyl)- methoxy]ethyl]-1H-imidazole nitrate Alforix; Albistat; Conoderm; Daktarin; Fungiderm; Monistat; Vodol 22832-87-7 ≥98% 479.15 C18H14Cl4N2 HNO3 C1=CC(=C(C=C1Cl)Cl)COC(CN2C=CN=C2)C3=C(C=C(C=C3)Cl)Cl.[N+](=O)(O)[O-] Ambient Ambient Soluble in methanol (13 mg/mL), ethanol (3 mg/mL).  Practically insoluble in water. "Park JY, Jung HJ, Seo I, et al. Translational suppression of HIF-1α by miconazole through the mTOR signaling pathway. Cell Oncol (Dordr). 2014 Jul 29. [Epub ahead of print]. PMID: 25070654.

 

Niimi M, Firth NA, Cannon RD. Antifungal drug resistance of oral fungi. Odontology. 2010 Feb;98(1):15-25. PMID: 20155503.

 

Duret C, Daujat-Chavanieu M, Pascussi JM, et al. Ketoconazole and miconazole are antagonists of the human glucocorticoid receptor: consequences on the expression and function of the constitutive androstane receptor and the pregnane X receptor. Mol Pharmacol. 2006 Jul;70(1):329-39. PMID: 16608920.

" Xn Not dangerous goods.

LKT M3310 Miconazole Nitrate 5 g 144.1 Imidazole; 14-α demethylase inhibitor, potential glucocorticoid antagonist. 1-[2-(2,4-Dichlorophenyl)-2-[(2,4-dichlorophenyl)- methoxy]ethyl]-1H-imidazole nitrate Alforix; Albistat; Conoderm; Daktarin; Fungiderm; Monistat; Vodol 22832-87-7 ≥98% 479.15 C18H14Cl4N2 HNO3 C1=CC(=C(C=C1Cl)Cl)COC(CN2C=CN=C2)C3=C(C=C(C=C3)Cl)Cl.[N+](=O)(O)[O-] Ambient Ambient Soluble in methanol (13 mg/mL), ethanol (3 mg/mL).  Practically insoluble in water. "Park JY, Jung HJ, Seo I, et al. Translational suppression of HIF-1α by miconazole through the mTOR signaling pathway. Cell Oncol (Dordr). 2014 Jul 29. [Epub ahead of print]. PMID: 25070654.

 

Niimi M, Firth NA, Cannon RD. Antifungal drug resistance of oral fungi. Odontology. 2010 Feb;98(1):15-25. PMID: 20155503.

 

Duret C, Daujat-Chavanieu M, Pascussi JM, et al. Ketoconazole and miconazole are antagonists of the human glucocorticoid receptor: consequences on the expression and function of the constitutive androstane receptor and the pregnane X receptor. Mol Pharmacol. 2006 Jul;70(1):329-39. PMID: 16608920.

" Xn Not dangerous goods.

LKT M3310 Miconazole Nitrate 25 g 461 Imidazole; 14-α demethylase inhibitor, potential glucocorticoid antagonist. 1-[2-(2,4-Dichlorophenyl)-2-[(2,4-dichlorophenyl)- methoxy]ethyl]-1H-imidazole nitrate Alforix; Albistat; Conoderm; Daktarin; Fungiderm; Monistat; Vodol 22832-87-7 ≥98% 479.15 C18H14Cl4N2 HNO3 C1=CC(=C(C=C1Cl)Cl)COC(CN2C=CN=C2)C3=C(C=C(C=C3)Cl)Cl.[N+](=O)(O)[O-] Ambient Ambient Soluble in methanol (13 mg/mL), ethanol (3 mg/mL).  Practically insoluble in water. "Park JY, Jung HJ, Seo I, et al. Translational suppression of HIF-1α by miconazole through the mTOR signaling pathway. Cell Oncol (Dordr). 2014 Jul 29. [Epub ahead of print]. PMID: 25070654.

 

Niimi M, Firth NA, Cannon RD. Antifungal drug resistance of oral fungi. Odontology. 2010 Feb;98(1):15-25. PMID: 20155503.

 

Duret C, Daujat-Chavanieu M, Pascussi JM, et al. Ketoconazole and miconazole are antagonists of the human glucocorticoid receptor: consequences on the expression and function of the constitutive androstane receptor and the pregnane X receptor. Mol Pharmacol. 2006 Jul;70(1):329-39. PMID: 16608920.

" Xn Not dangerous goods.

LKT M3321 Mifepristone 100 mg 27.2 Synthetic steroid, contraceptive; PR and glucocorticoid antagonist. (11β,17β)-11-[4-(Dimethylamino)phenyl]-17- hydroxy-17-(1-propynyl)estra-4,9-dien-3-one RU-486; Mifegyne; Mifeprex 84371-65-3 ≥98% 429.59 C29H35NO2 CC#CC1(CCC2C1(CC(C3=C4CCC(=O)C=C4CCC23)C5=CC=C(C=C5)N(C)C)C)O Ambient Ambient Soluble in methanol, chloroform, or acetone. "Fiala C, Gemzel-Danielsson K. Review of medical abortion using mifepristone in combination with a prostaglandin analogue. Contraception. 2006 Jul;74(1):66-86. PMID: 16781264.

 

Young AH, Gallagher P, Watson S, et al. Improvements in neurocognitive function and mood following adjunctive treatment with mifepristone (RU-486) in bipolar disorder. Neuropsychopharmacology. 2004 Aug;29(8):1538-45. PMID: 15127079.

 

Behl C, Trapp T, Skutella T, et al. Protection against oxidative stress-induced neuronal cell death--a novel role for RU486. Eur J Neurosci. 1997 May;9(5):912-20. PMID: 9182944. 

" T Not dangerous goods.

LKT M3321 Mifepristone 500 mg 115.5 Synthetic steroid, contraceptive; PR and glucocorticoid antagonist. (11β,17β)-11-[4-(Dimethylamino)phenyl]-17- hydroxy-17-(1-propynyl)estra-4,9-dien-3-one RU-486; Mifegyne; Mifeprex 84371-65-3 ≥98% 429.59 C29H35NO2 CC#CC1(CCC2C1(CC(C3=C4CCC(=O)C=C4CCC23)C5=CC=C(C=C5)N(C)C)C)O Ambient Ambient Soluble in methanol, chloroform, or acetone. "Fiala C, Gemzel-Danielsson K. Review of medical abortion using mifepristone in combination with a prostaglandin analogue. Contraception. 2006 Jul;74(1):66-86. PMID: 16781264.

 

Young AH, Gallagher P, Watson S, et al. Improvements in neurocognitive function and mood following adjunctive treatment with mifepristone (RU-486) in bipolar disorder. Neuropsychopharmacology. 2004 Aug;29(8):1538-45. PMID: 15127079.

 

Behl C, Trapp T, Skutella T, et al. Protection against oxidative stress-induced neuronal cell death--a novel role for RU486. Eur J Neurosci. 1997 May;9(5):912-20. PMID: 9182944. 

" T Not dangerous goods.

LKT M3321 Mifepristone 1 g 203.8 Synthetic steroid, contraceptive; PR and glucocorticoid antagonist. (11β,17β)-11-[4-(Dimethylamino)phenyl]-17- hydroxy-17-(1-propynyl)estra-4,9-dien-3-one RU-486; Mifegyne; Mifeprex 84371-65-3 ≥98% 429.59 C29H35NO2 CC#CC1(CCC2C1(CC(C3=C4CCC(=O)C=C4CCC23)C5=CC=C(C=C5)N(C)C)C)O Ambient Ambient Soluble in methanol, chloroform, or acetone. "Fiala C, Gemzel-Danielsson K. Review of medical abortion using mifepristone in combination with a prostaglandin analogue. Contraception. 2006 Jul;74(1):66-86. PMID: 16781264.

 

Young AH, Gallagher P, Watson S, et al. Improvements in neurocognitive function and mood following adjunctive treatment with mifepristone (RU-486) in bipolar disorder. Neuropsychopharmacology. 2004 Aug;29(8):1538-45. PMID: 15127079.

 

Behl C, Trapp T, Skutella T, et al. Protection against oxidative stress-induced neuronal cell death--a novel role for RU486. Eur J Neurosci. 1997 May;9(5):912-20. PMID: 9182944. 

" T Not dangerous goods.

LKT S3033 Shikimic Acid 1 g 64.7 Cyclohexanecarboxylic acid found in various plants and microorganisms. [3R-(3α,3aβ,4α,7α,8a,8aα)]-2,3,4,7,8,8a-Hexahydro-4-hydroxy-8(hydroxymethyl)-8-methyl-1H-3a,7- methanoazulene-3,5-dicarboxylic acid Shikimate 138-59-0 ≥98% 174.15 C7H10O5 C1C(C(C(C=C1C(=O)O)O)O)O Sublimes. Ambient Ambient Soluble in water (1.8 g/L). Practically insoluble  in chloroform and benzene. "Manna K, Khan A, Kr Das D, et al. Protective effect of coconut water concentrate and its active component shikimic acid against hydroperoxide mediated oxidative stress through suppression of NF-κB and activation of Nrf2 pathway. J Ethnopharmacol. 2014 May 14. [Epub ahead of print]. PMID: 24835026.

 

Xing J, You C, Dong K, et al. Ameliorative effects of 3,4-oxo-isopropylidene-shikimic acid on experimental colitis and their mechanisms in rats. Int Immunopharmacol. 2013 Mar;15(3):524-31. PMID: 23434856.

 

Morucci F, Lopez P, Miño J, et al. Antinociceptive activity of aqueous extract and isolated compounds of Lithrea molleoides. J Ethnopharmacol. 2012 Jul 13;142(2):401-6. PMID: 22609809.

" None Not dangerous goods.

LKT S3033 Shikimic Acid 5 g 213.6 Cyclohexanecarboxylic acid found in various plants and microorganisms. [3R-(3α,3aβ,4α,7α,8a,8aα)]-2,3,4,7,8,8a-Hexahydro-4-hydroxy-8(hydroxymethyl)-8-methyl-1H-3a,7- methanoazulene-3,5-dicarboxylic acid Shikimate 138-59-0 ≥98% 174.15 C7H10O5 C1C(C(C(C=C1C(=O)O)O)O)O Sublimes. Ambient Ambient Soluble in water (1.8 g/L). Practically insoluble  in chloroform and benzene. "Manna K, Khan A, Kr Das D, et al. Protective effect of coconut water concentrate and its active component shikimic acid against hydroperoxide mediated oxidative stress through suppression of NF-κB and activation of Nrf2 pathway. J Ethnopharmacol. 2014 May 14. [Epub ahead of print]. PMID: 24835026.

 

Xing J, You C, Dong K, et al. Ameliorative effects of 3,4-oxo-isopropylidene-shikimic acid on experimental colitis and their mechanisms in rats. Int Immunopharmacol. 2013 Mar;15(3):524-31. PMID: 23434856.

 

Morucci F, Lopez P, Miño J, et al. Antinociceptive activity of aqueous extract and isolated compounds of Lithrea molleoides. J Ethnopharmacol. 2012 Jul 13;142(2):401-6. PMID: 22609809.

" None Not dangerous goods.

LKT M3344 Milrinone 10 mg 89.3 PDE3 inhibitor. 5,8-Dihydro-5-methoxy-8-oxo-1,3-dioxolo[4,5-g]- quinoline-7-carboxylic acid Corotrope; Milrila 78415-72-2 ≥98% 211.22 C12H9N3O CC1=C(C=C(C(=O)N1)C#N)C2=CC=NC=C2 Ambient Ambient Soluble in DMSO (>10mg/mL). "Hiramatsu N, Kageyama K. Anti-thrombotic effect of milrinone is caused by inhibition of calcium release from the dense tubular system in human platelets. Acta Anaesthesiol Scand. 2003 Jan;47(1):53-7. PMID: 12492797.

 

Yano M, Kohno M, Ohkusa T, et al. Effect of milrinone on left ventricular relaxation and Ca(2+) uptake function of cardiac sarcoplasmic reticulum. Am J Physiol Heart Circ Physiol. 2000 Oct;279(4):H1898-905. PMID: 11009478.

" T "UN number: 2811     Class:  6.1     Packing group:  III

Proper shipping name:  Toxic solids, organic, n.o.s. (Milrinone)"

LKT M3344 Milrinone 50 mg 368.8 PDE3 inhibitor. 5,8-Dihydro-5-methoxy-8-oxo-1,3-dioxolo[4,5-g]- quinoline-7-carboxylic acid Corotrope; Milrila 78415-72-2 ≥98% 211.22 C12H9N3O CC1=C(C=C(C(=O)N1)C#N)C2=CC=NC=C2 Ambient Ambient Soluble in DMSO (>10mg/mL). "Hiramatsu N, Kageyama K. Anti-thrombotic effect of milrinone is caused by inhibition of calcium release from the dense tubular system in human platelets. Acta Anaesthesiol Scand. 2003 Jan;47(1):53-7. PMID: 12492797.

 

Yano M, Kohno M, Ohkusa T, et al. Effect of milrinone on left ventricular relaxation and Ca(2+) uptake function of cardiac sarcoplasmic reticulum. Am J Physiol Heart Circ Physiol. 2000 Oct;279(4):H1898-905. PMID: 11009478.

" T "UN number: 2811     Class:  6.1     Packing group:  III

Proper shipping name:  Toxic solids, organic, n.o.s. (Milrinone)"

LKT M3344 Milrinone 100 mg 635.4 PDE3 inhibitor. 5,8-Dihydro-5-methoxy-8-oxo-1,3-dioxolo[4,5-g]- quinoline-7-carboxylic acid Corotrope; Milrila 78415-72-2 ≥98% 211.22 C12H9N3O CC1=C(C=C(C(=O)N1)C#N)C2=CC=NC=C2 Ambient Ambient Soluble in DMSO (>10mg/mL). "Hiramatsu N, Kageyama K. Anti-thrombotic effect of milrinone is caused by inhibition of calcium release from the dense tubular system in human platelets. Acta Anaesthesiol Scand. 2003 Jan;47(1):53-7. PMID: 12492797.

 

Yano M, Kohno M, Ohkusa T, et al. Effect of milrinone on left ventricular relaxation and Ca(2+) uptake function of cardiac sarcoplasmic reticulum. Am J Physiol Heart Circ Physiol. 2000 Oct;279(4):H1898-905. PMID: 11009478.

" T "UN number: 2811     Class:  6.1     Packing group:  III

Proper shipping name:  Toxic solids, organic, n.o.s. (Milrinone)"

LKT S2044 SFLLR 1 mg 96 Synthetic peptide; PAR1 agonist. ≥95% 634.78 C30H50N8O7 Ambient -20°C "Wu X, Zhang W, Li JY, et al. Induction of apoptosis by thrombin in the cultured neurons of dorsal motor nucleus of the vagus. Neurogastroenterol Motil. 2011 Mar;23(3):279-85, e123-4. PMID: 21143557.

 

Pinet C, Algalarrondo V, Sablayrolles S, et al. Protease-activated receptor-1 mediates thrombin-induced persistent sodium current in human cardiomyocytes. Mol Pharmacol. 2008 Jun;73(6):1622-31. PMID: 18326052.

 

Wang L, Luo J, He S. Induction of MMP-9 release from human dermal fibroblasts by thrombin: involvement of JAK/STAT3 signaling pathway in MMP-9 release. BMC Cell Biol. 2007 May 7;8:14. PMID: 17480240.

 

Li T, He S. Induction of IL-6 release from human T cells by PAR-1 and PAR-2 agonists. Immunol Cell Biol. 2006 Oct;84(5):461-6. PMID: 16869943.

 

Maragoudakis ME, Kraniti N, Giannopoulou E, et al. Modulation of angiogenesis and progelatinase a by thrombin receptor mimetics and antagonists. Endothelium. 2001;8(3):195-205. PMID: 11824472.

 

Sabo T, Gurwitz D, Motola L, et al. Structure-activity studies of the thrombin receptor activating peptide. Biochem Biophys Res Commun. 1992 Oct 30;188(2):604-10. PMID: 1332704.

" Not dangerous goods.

LKT S2044 SFLLR 2 mg 162 Synthetic peptide; PAR1 agonist. ≥95% 634.78 C30H50N8O7 Ambient -20°C "Wu X, Zhang W, Li JY, et al. Induction of apoptosis by thrombin in the cultured neurons of dorsal motor nucleus of the vagus. Neurogastroenterol Motil. 2011 Mar;23(3):279-85, e123-4. PMID: 21143557.

 

Pinet C, Algalarrondo V, Sablayrolles S, et al. Protease-activated receptor-1 mediates thrombin-induced persistent sodium current in human cardiomyocytes. Mol Pharmacol. 2008 Jun;73(6):1622-31. PMID: 18326052.

 

Wang L, Luo J, He S. Induction of MMP-9 release from human dermal fibroblasts by thrombin: involvement of JAK/STAT3 signaling pathway in MMP-9 release. BMC Cell Biol. 2007 May 7;8:14. PMID: 17480240.

 

Li T, He S. Induction of IL-6 release from human T cells by PAR-1 and PAR-2 agonists. Immunol Cell Biol. 2006 Oct;84(5):461-6. PMID: 16869943.

 

Maragoudakis ME, Kraniti N, Giannopoulou E, et al. Modulation of angiogenesis and progelatinase a by thrombin receptor mimetics and antagonists. Endothelium. 2001;8(3):195-205. PMID: 11824472.

 

Sabo T, Gurwitz D, Motola L, et al. Structure-activity studies of the thrombin receptor activating peptide. Biochem Biophys Res Commun. 1992 Oct 30;188(2):604-10. PMID: 1332704.

" Not dangerous goods.

LKT S2044 SFLLR 5 mg 287.9 Synthetic peptide; PAR1 agonist. ≥95% 634.78 C30H50N8O7 Ambient -20°C "Wu X, Zhang W, Li JY, et al. Induction of apoptosis by thrombin in the cultured neurons of dorsal motor nucleus of the vagus. Neurogastroenterol Motil. 2011 Mar;23(3):279-85, e123-4. PMID: 21143557.

 

Pinet C, Algalarrondo V, Sablayrolles S, et al. Protease-activated receptor-1 mediates thrombin-induced persistent sodium current in human cardiomyocytes. Mol Pharmacol. 2008 Jun;73(6):1622-31. PMID: 18326052.

 

Wang L, Luo J, He S. Induction of MMP-9 release from human dermal fibroblasts by thrombin: involvement of JAK/STAT3 signaling pathway in MMP-9 release. BMC Cell Biol. 2007 May 7;8:14. PMID: 17480240.

 

Li T, He S. Induction of IL-6 release from human T cells by PAR-1 and PAR-2 agonists. Immunol Cell Biol. 2006 Oct;84(5):461-6. PMID: 16869943.

 

Maragoudakis ME, Kraniti N, Giannopoulou E, et al. Modulation of angiogenesis and progelatinase a by thrombin receptor mimetics and antagonists. Endothelium. 2001;8(3):195-205. PMID: 11824472.

 

Sabo T, Gurwitz D, Motola L, et al. Structure-activity studies of the thrombin receptor activating peptide. Biochem Biophys Res Commun. 1992 Oct 30;188(2):604-10. PMID: 1332704.

" Not dangerous goods.

LKT S1971 Sertraline Hydrochloride 500 mg 65.6 FIASMA, SERT and DAT inhibitor, α1-adrenergic antagonist, potential σ1 antagonist. (1S-cis)-4-(3,4-dichlorophenyl)-1,2,3,4-tetrahydro-N-methyl-1-naphthalenamine hydrochloride Lustral; Zoloft 79559-97-0 ≥98% 342.7 C17H17Cl2N HCl CNC1CCC(C2=CC=CC=C12)C3=CC(=C(C=C3)Cl)Cl.Cl Ambient Ambient Slightly soluble in water and isopropyl alcohol. Sparingly soluble in ethanol. "Guaiana G, Gupta S, Chiodo D, et al. Agomelatine versus other antidepressive agents for major depression. Cochrane Database Syst Rev. 2013 Dec 17;12:CD008851. PMID: 24343836.

 

Zhu H, Bogdanov MB, Boyle SH, et al. Pharmacometabolomics of response to sertraline and to placebo in major depressive disorder - possible role for methoxyindole pathway. PLoS One. 2013 Jul 17;8(7):e68283. PMID: 23874572.

 

Hodge JM, Wang Y, Berk M, et al. Selective serotonin reuptake inhibitors inhibit human osteoclast and osteoblast formation and function. Biol Psychiatry. 2013 Jul 1;74(1):32-9. PMID: 23260229.

 

Meyer JH, Wilson AA, Sagrati S, et al. Serotonin transporter occupancy of five selective serotonin reuptake inhibitors at different doses: an [11C]DASB positron emission tomography study. Am J Psychiatry. 2004 May;161(5):826-35. PMID: 15121647.

" None Not dangerous goods.

LKT S1971 Sertraline Hydrochloride 1 g 93.8 FIASMA, SERT and DAT inhibitor, α1-adrenergic antagonist, potential σ1 antagonist. (1S-cis)-4-(3,4-dichlorophenyl)-1,2,3,4-tetrahydro-N-methyl-1-naphthalenamine hydrochloride Lustral; Zoloft 79559-97-0 ≥98% 342.7 C17H17Cl2N HCl CNC1CCC(C2=CC=CC=C12)C3=CC(=C(C=C3)Cl)Cl.Cl Ambient Ambient Slightly soluble in water and isopropyl alcohol. Sparingly soluble in ethanol. "Guaiana G, Gupta S, Chiodo D, et al. Agomelatine versus other antidepressive agents for major depression. Cochrane Database Syst Rev. 2013 Dec 17;12:CD008851. PMID: 24343836.

 

Zhu H, Bogdanov MB, Boyle SH, et al. Pharmacometabolomics of response to sertraline and to placebo in major depressive disorder - possible role for methoxyindole pathway. PLoS One. 2013 Jul 17;8(7):e68283. PMID: 23874572.

 

Hodge JM, Wang Y, Berk M, et al. Selective serotonin reuptake inhibitors inhibit human osteoclast and osteoblast formation and function. Biol Psychiatry. 2013 Jul 1;74(1):32-9. PMID: 23260229.

 

Meyer JH, Wilson AA, Sagrati S, et al. Serotonin transporter occupancy of five selective serotonin reuptake inhibitors at different doses: an [11C]DASB positron emission tomography study. Am J Psychiatry. 2004 May;161(5):826-35. PMID: 15121647.

" None Not dangerous goods.

LKT S1971 Sertraline Hydrochloride 5 g 346.9 FIASMA, SERT and DAT inhibitor, α1-adrenergic antagonist, potential σ1 antagonist. (1S-cis)-4-(3,4-dichlorophenyl)-1,2,3,4-tetrahydro-N-methyl-1-naphthalenamine hydrochloride Lustral; Zoloft 79559-97-0 ≥98% 342.7 C17H17Cl2N HCl CNC1CCC(C2=CC=CC=C12)C3=CC(=C(C=C3)Cl)Cl.Cl Ambient Ambient Slightly soluble in water and isopropyl alcohol. Sparingly soluble in ethanol. "Guaiana G, Gupta S, Chiodo D, et al. Agomelatine versus other antidepressive agents for major depression. Cochrane Database Syst Rev. 2013 Dec 17;12:CD008851. PMID: 24343836.

 

Zhu H, Bogdanov MB, Boyle SH, et al. Pharmacometabolomics of response to sertraline and to placebo in major depressive disorder - possible role for methoxyindole pathway. PLoS One. 2013 Jul 17;8(7):e68283. PMID: 23874572.

 

Hodge JM, Wang Y, Berk M, et al. Selective serotonin reuptake inhibitors inhibit human osteoclast and osteoblast formation and function. Biol Psychiatry. 2013 Jul 1;74(1):32-9. PMID: 23260229.

 

Meyer JH, Wilson AA, Sagrati S, et al. Serotonin transporter occupancy of five selective serotonin reuptake inhibitors at different doses: an [11C]DASB positron emission tomography study. Am J Psychiatry. 2004 May;161(5):826-35. PMID: 15121647.

" None Not dangerous goods.

LKT M3368 Mirtazapine 10 mg 83.7 Piperazine; 5-HT1 agonist, 5-HT2/3 and α2-adrenergic antagonist, histamine H1 inverse agonist. "Pyrazino(2,1-a)pyrido(2,3-c)(2)benzazepine, 1,2,3,4,10,14b-hexahydro-2-methyl- 

" Remeron 61337-67-5 ≥98% 265.35 C17H19N3 CN1CCN2C(C1)C3=CC=CC=C3CC4=C2N=CC=C4 Ambient Ambient Soluble in DMSO (~8mg/mL). "Kongsakon R, Papadopoulos KI, Saguansiritham R. Mirtazapine in amphetamine detoxification: a placebo-controlled pilot study. Int Clin Psychopharmacol. 2005 Sep;20(5):253-6. PMID: 16096515.

 

Liappas J, Paparrigopoulos T, Malitas P, et al. Mirtazapine improves alcohol detoxification. J Psychopharmacol. 2004 Mar;18(1):88-93. PMID: 15107190.

 

Nutt DJ. Tolerability and safety aspects of mirtazapine. Hum Psychopharmacol. 2002 Jun;17 Suppl 1:S37-41. PMID: 12404669.

 

Posey DJ, Guenin KD, Kohn AE, et al. A naturalistic open-label study of mirtazapine in autistic and other pervasive developmental disorders. J Child Adolesc Psychopharmacol. 2001 Fall;11(3):267-77. PMID: 11642476.

 

Anttila SA, Leinonen EV. A review of the pharmacological and clinical profile of mirtazapine. CNS Drug Rev. 2001 Fall;7(3):249-64. PMID: 11607047.

 

de Boer TH, Maura G, Raiteri M, et al. Neurochemical and autonomic pharmacological profiles of the 6-aza-analogue of mianserin, Org 3770 and its enantiomers. Neuropharmacology. 1988 Apr;27(4):399-408. PMID: 3419539.

" None Not dangerous goods.

LKT M3368 Mirtazapine 50 mg 335 Piperazine; 5-HT1 agonist, 5-HT2/3 and α2-adrenergic antagonist, histamine H1 inverse agonist. "Pyrazino(2,1-a)pyrido(2,3-c)(2)benzazepine, 1,2,3,4,10,14b-hexahydro-2-methyl- 

" Remeron 61337-67-5 ≥98% 265.35 C17H19N3 CN1CCN2C(C1)C3=CC=CC=C3CC4=C2N=CC=C4 Ambient Ambient Soluble in DMSO (~8mg/mL). "Kongsakon R, Papadopoulos KI, Saguansiritham R. Mirtazapine in amphetamine detoxification: a placebo-controlled pilot study. Int Clin Psychopharmacol. 2005 Sep;20(5):253-6. PMID: 16096515.

 

Liappas J, Paparrigopoulos T, Malitas P, et al. Mirtazapine improves alcohol detoxification. J Psychopharmacol. 2004 Mar;18(1):88-93. PMID: 15107190.

 

Nutt DJ. Tolerability and safety aspects of mirtazapine. Hum Psychopharmacol. 2002 Jun;17 Suppl 1:S37-41. PMID: 12404669.

 

Posey DJ, Guenin KD, Kohn AE, et al. A naturalistic open-label study of mirtazapine in autistic and other pervasive developmental disorders. J Child Adolesc Psychopharmacol. 2001 Fall;11(3):267-77. PMID: 11642476.

 

Anttila SA, Leinonen EV. A review of the pharmacological and clinical profile of mirtazapine. CNS Drug Rev. 2001 Fall;7(3):249-64. PMID: 11607047.

 

de Boer TH, Maura G, Raiteri M, et al. Neurochemical and autonomic pharmacological profiles of the 6-aza-analogue of mianserin, Org 3770 and its enantiomers. Neuropharmacology. 1988 Apr;27(4):399-408. PMID: 3419539.

" None Not dangerous goods.

LKT M3368 Mirtazapine 250 mg 1088.3 Piperazine; 5-HT1 agonist, 5-HT2/3 and α2-adrenergic antagonist, histamine H1 inverse agonist. "Pyrazino(2,1-a)pyrido(2,3-c)(2)benzazepine, 1,2,3,4,10,14b-hexahydro-2-methyl- 

" Remeron 61337-67-5 ≥98% 265.35 C17H19N3 CN1CCN2C(C1)C3=CC=CC=C3CC4=C2N=CC=C4 Ambient Ambient Soluble in DMSO (~8mg/mL). "Kongsakon R, Papadopoulos KI, Saguansiritham R. Mirtazapine in amphetamine detoxification: a placebo-controlled pilot study. Int Clin Psychopharmacol. 2005 Sep;20(5):253-6. PMID: 16096515.

 

Liappas J, Paparrigopoulos T, Malitas P, et al. Mirtazapine improves alcohol detoxification. J Psychopharmacol. 2004 Mar;18(1):88-93. PMID: 15107190.

 

Nutt DJ. Tolerability and safety aspects of mirtazapine. Hum Psychopharmacol. 2002 Jun;17 Suppl 1:S37-41. PMID: 12404669.

 

Posey DJ, Guenin KD, Kohn AE, et al. A naturalistic open-label study of mirtazapine in autistic and other pervasive developmental disorders. J Child Adolesc Psychopharmacol. 2001 Fall;11(3):267-77. PMID: 11642476.

 

Anttila SA, Leinonen EV. A review of the pharmacological and clinical profile of mirtazapine. CNS Drug Rev. 2001 Fall;7(3):249-64. PMID: 11607047.

 

de Boer TH, Maura G, Raiteri M, et al. Neurochemical and autonomic pharmacological profiles of the 6-aza-analogue of mianserin, Org 3770 and its enantiomers. Neuropharmacology. 1988 Apr;27(4):399-408. PMID: 3419539.

" None Not dangerous goods.

LKT S1970 Serum Thymic Factor 1 mg 60 Synthetic peptide hormone. FTS 63958-90-7 ≥95% 858.89 C33H54N12O15 CC(C(=O)NC(CCCCN)C(=O)NC(CO)C(=O)NC(CCC(=O)N)C(=O)NCC(=O)NCC(=O)NC(CO)C(=O)NC(CC(=O)N)C(=O)O)NC(=O)C1CCC(=O)N1 Ambient -20°C "Kohda Y, Matsunaga Y, Yonogi K, et al. Protective effect of serum thymic factor, FTS, on cephaloridine-induced nephrotoxicity in rats. Biol Pharm Bull. 2005 Nov;28(11):2087-91. PMID: 16272694.

 

Saitoh N, Awaya A, Sakudo A, et al. Serum thymic factor prevents LPS-induced pancreatic cell damage in mice via up-regulation of Bcl-2 expression in pancreas. Microbiol Immunol. 2004;48(9):629-38. PMID: 15383698.

 

Mizutani M, El-Fotoh M, Mori M, et al. In vivo administration of serum thymic factor (FTS) prevents EMC-D virus-induced diabetes and myocarditis in BALB/cAJcl mice. Arch Virol. 1996;141(1):73-83. PMID: 8629952.

 

Kato S, Nakamura H. Suppression of acute experimental allergic encephalomyelitis by synthetic serum thymic factor. Clinical, histopathological, and immunohistochemical studies. Acta Neuropathol. 1988;75(4):337-44. PMID: 2834909.

 

Kaiserlian D, Bardos P, Bach JF. In vitro modulation of mouse natural killer (NK) cell activity by the serum thymic factor (FTS). Cell Immunol. 1983 Mar;76(2):232-42. PMID: 6682352.

"

LKT S1970 Serum Thymic Factor 2 mg 101.9 Synthetic peptide hormone. FTS 63958-90-7 ≥95% 858.89 C33H54N12O15 CC(C(=O)NC(CCCCN)C(=O)NC(CO)C(=O)NC(CCC(=O)N)C(=O)NCC(=O)NCC(=O)NC(CO)C(=O)NC(CC(=O)N)C(=O)O)NC(=O)C1CCC(=O)N1 Ambient -20°C "Kohda Y, Matsunaga Y, Yonogi K, et al. Protective effect of serum thymic factor, FTS, on cephaloridine-induced nephrotoxicity in rats. Biol Pharm Bull. 2005 Nov;28(11):2087-91. PMID: 16272694.

 

Saitoh N, Awaya A, Sakudo A, et al. Serum thymic factor prevents LPS-induced pancreatic cell damage in mice via up-regulation of Bcl-2 expression in pancreas. Microbiol Immunol. 2004;48(9):629-38. PMID: 15383698.

 

Mizutani M, El-Fotoh M, Mori M, et al. In vivo administration of serum thymic factor (FTS) prevents EMC-D virus-induced diabetes and myocarditis in BALB/cAJcl mice. Arch Virol. 1996;141(1):73-83. PMID: 8629952.

 

Kato S, Nakamura H. Suppression of acute experimental allergic encephalomyelitis by synthetic serum thymic factor. Clinical, histopathological, and immunohistochemical studies. Acta Neuropathol. 1988;75(4):337-44. PMID: 2834909.

 

Kaiserlian D, Bardos P, Bach JF. In vitro modulation of mouse natural killer (NK) cell activity by the serum thymic factor (FTS). Cell Immunol. 1983 Mar;76(2):232-42. PMID: 6682352.

"

LKT S1970 Serum Thymic Factor 5 mg 180 Synthetic peptide hormone. FTS 63958-90-7 ≥95% 858.89 C33H54N12O15 CC(C(=O)NC(CCCCN)C(=O)NC(CO)C(=O)NC(CCC(=O)N)C(=O)NCC(=O)NCC(=O)NC(CO)C(=O)NC(CC(=O)N)C(=O)O)NC(=O)C1CCC(=O)N1 Ambient -20°C "Kohda Y, Matsunaga Y, Yonogi K, et al. Protective effect of serum thymic factor, FTS, on cephaloridine-induced nephrotoxicity in rats. Biol Pharm Bull. 2005 Nov;28(11):2087-91. PMID: 16272694.

 

Saitoh N, Awaya A, Sakudo A, et al. Serum thymic factor prevents LPS-induced pancreatic cell damage in mice via up-regulation of Bcl-2 expression in pancreas. Microbiol Immunol. 2004;48(9):629-38. PMID: 15383698.

 

Mizutani M, El-Fotoh M, Mori M, et al. In vivo administration of serum thymic factor (FTS) prevents EMC-D virus-induced diabetes and myocarditis in BALB/cAJcl mice. Arch Virol. 1996;141(1):73-83. PMID: 8629952.

 

Kato S, Nakamura H. Suppression of acute experimental allergic encephalomyelitis by synthetic serum thymic factor. Clinical, histopathological, and immunohistochemical studies. Acta Neuropathol. 1988;75(4):337-44. PMID: 2834909.

 

Kaiserlian D, Bardos P, Bach JF. In vitro modulation of mouse natural killer (NK) cell activity by the serum thymic factor (FTS). Cell Immunol. 1983 Mar;76(2):232-42. PMID: 6682352.

"

LKT M3377 Mitomycin C 1 mg 37.5 Alkaloid produced by Streptomyces, DNA cross-linker; thioredoxin reductase inhibitor. [1aS-(1aα,8β,8aα,8bα)]-6-Amino-8-[[aminocarbonyl)oxy]methyl]-1,1a,2,8,8a,8b-hexahydro-8a-methoxy-5- methylazirino[2',3':3,4]pyrrolo[1,2-a]indole-4,7-dione MMC; Ametycine; Mitocin-C; Mutamycin 50-07-7 ≥98% 334.33 C15H18N4O5 CC1=C(C(=O)C2=C(C1=O)N3CC4C(C3(C2COC(=O)N)OC)N4)N Ambient -20°C Soluble in water (25 oC - 0.9 mg/mL), acetone, methanol, or ethanol (1 mg/mL), DMSO (15 mg/mL) "Liu L, Wang F, Zheng Y, et al. Pretreatment of transfused donor splenocytes and allografts with mitomycin C attenuates acute rejection in heart transplantation in mice. Transplant Proc. 2014 May;46(4):1169-74. PMID: 24815153.

 

Paz MM, Zhang X, Lu J, et al. A new mechanism of action for the anticancer drug mitomycin C: mechanism-based inhibition of thioredoxin reductase. Chem Res Toxicol. 2012 Jul 16;25(7):1502-11. PMID: 22694104.

 

Kang YH, Lee KA, Kim JH, et al. Mitomycin C modulates DNA-double strand break repair genes in cervical carcinoma cells. Amino Acids. 2010 Nov;39(5):1291-8. PMID: 20352460.

 

Tomasz M. Mitomycin C: small, fast and deadly (but very selective). Chem Biol. 1995 Sep;2(9):575-9. PMID: 9383461." T, Carc. "UN number: 2811     Class: 6.1    Packing Group: II

Proper shipping name: Toxic solid, organic, n.o.s. (Mitomycin C)"

LKT M3377 Mitomycin C 5 mg 78.6 Alkaloid produced by Streptomyces, DNA cross-linker; thioredoxin reductase inhibitor. [1aS-(1aα,8β,8aα,8bα)]-6-Amino-8-[[aminocarbonyl)oxy]methyl]-1,1a,2,8,8a,8b-hexahydro-8a-methoxy-5- methylazirino[2',3':3,4]pyrrolo[1,2-a]indole-4,7-dione MMC; Ametycine; Mitocin-C; Mutamycin 50-07-7 ≥98% 334.33 C15H18N4O5 CC1=C(C(=O)C2=C(C1=O)N3CC4C(C3(C2COC(=O)N)OC)N4)N Ambient -20°C Soluble in water (25 oC - 0.9 mg/mL), acetone, methanol, or ethanol (1 mg/mL), DMSO (15 mg/mL) "Liu L, Wang F, Zheng Y, et al. Pretreatment of transfused donor splenocytes and allografts with mitomycin C attenuates acute rejection in heart transplantation in mice. Transplant Proc. 2014 May;46(4):1169-74. PMID: 24815153.

 

Paz MM, Zhang X, Lu J, et al. A new mechanism of action for the anticancer drug mitomycin C: mechanism-based inhibition of thioredoxin reductase. Chem Res Toxicol. 2012 Jul 16;25(7):1502-11. PMID: 22694104.

 

Kang YH, Lee KA, Kim JH, et al. Mitomycin C modulates DNA-double strand break repair genes in cervical carcinoma cells. Amino Acids. 2010 Nov;39(5):1291-8. PMID: 20352460.

 

Tomasz M. Mitomycin C: small, fast and deadly (but very selective). Chem Biol. 1995 Sep;2(9):575-9. PMID: 9383461." T, Carc. "UN number: 2811     Class: 6.1    Packing Group: II

Proper shipping name: Toxic solid, organic, n.o.s. (Mitomycin C)"

LKT M3377 Mitomycin C 10 mg 134.9 Alkaloid produced by Streptomyces, DNA cross-linker; thioredoxin reductase inhibitor. [1aS-(1aα,8β,8aα,8bα)]-6-Amino-8-[[aminocarbonyl)oxy]methyl]-1,1a,2,8,8a,8b-hexahydro-8a-methoxy-5- methylazirino[2',3':3,4]pyrrolo[1,2-a]indole-4,7-dione MMC; Ametycine; Mitocin-C; Mutamycin 50-07-7 ≥98% 334.33 C15H18N4O5 CC1=C(C(=O)C2=C(C1=O)N3CC4C(C3(C2COC(=O)N)OC)N4)N Ambient -20°C Soluble in water (25 oC - 0.9 mg/mL), acetone, methanol, or ethanol (1 mg/mL), DMSO (15 mg/mL) "Liu L, Wang F, Zheng Y, et al. Pretreatment of transfused donor splenocytes and allografts with mitomycin C attenuates acute rejection in heart transplantation in mice. Transplant Proc. 2014 May;46(4):1169-74. PMID: 24815153.

 

Paz MM, Zhang X, Lu J, et al. A new mechanism of action for the anticancer drug mitomycin C: mechanism-based inhibition of thioredoxin reductase. Chem Res Toxicol. 2012 Jul 16;25(7):1502-11. PMID: 22694104.

 

Kang YH, Lee KA, Kim JH, et al. Mitomycin C modulates DNA-double strand break repair genes in cervical carcinoma cells. Amino Acids. 2010 Nov;39(5):1291-8. PMID: 20352460.

 

Tomasz M. Mitomycin C: small, fast and deadly (but very selective). Chem Biol. 1995 Sep;2(9):575-9. PMID: 9383461." T, Carc. "UN number: 2811     Class: 6.1    Packing Group: II

Proper shipping name: Toxic solid, organic, n.o.s. (Mitomycin C)"

LKT S1968 Seratrodast 25 mg 112.5 TxA2 antagonist. 112665-43-7 ≥98% 354.44 C22H26O4 CC1=C(C(=O)C(=C(C1=O)C)C(CCCCCC(=O)O)C2=CC=CC=C2)C Ambient 4°C "An J, Li JQ, Wang T, et al. Blocking of thromboxane A2 receptor attenuates airway mucus hyperproduction induced by cigarette smoke. Eur J Pharmacol. 2013 Mar 5;703(1-3):11-7. PMID: 23399768.

 

Dogné JM, de Leval X, Benoit P, et al. Thromboxane A2 inhibition: therapeutic potential in bronchial asthma. Am J Respir Med. 2002;1(1):11-7. PMID: 14720071.

 

Ishiura Y, Fujimura M, Yamamori C, et al. Thromboxane antagonism and cough in chronic bronchitis. Ann Med. 2003;35(2):135-9. PMID: 12795341.

" Not dangerous goods.

LKT S1968 Seratrodast 100 mg 328.1 TxA2 antagonist. 112665-43-7 ≥98% 354.44 C22H26O4 CC1=C(C(=O)C(=C(C1=O)C)C(CCCCCC(=O)O)C2=CC=CC=C2)C Ambient 4°C "An J, Li JQ, Wang T, et al. Blocking of thromboxane A2 receptor attenuates airway mucus hyperproduction induced by cigarette smoke. Eur J Pharmacol. 2013 Mar 5;703(1-3):11-7. PMID: 23399768.

 

Dogné JM, de Leval X, Benoit P, et al. Thromboxane A2 inhibition: therapeutic potential in bronchial asthma. Am J Respir Med. 2002;1(1):11-7. PMID: 14720071.

 

Ishiura Y, Fujimura M, Yamamori C, et al. Thromboxane antagonism and cough in chronic bronchitis. Ann Med. 2003;35(2):135-9. PMID: 12795341.

" Not dangerous goods.

LKT S1968 Seratrodast 250 mg 656.3 TxA2 antagonist. 112665-43-7 ≥98% 354.44 C22H26O4 CC1=C(C(=O)C(=C(C1=O)C)C(CCCCCC(=O)O)C2=CC=CC=C2)C Ambient 4°C "An J, Li JQ, Wang T, et al. Blocking of thromboxane A2 receptor attenuates airway mucus hyperproduction induced by cigarette smoke. Eur J Pharmacol. 2013 Mar 5;703(1-3):11-7. PMID: 23399768.

 

Dogné JM, de Leval X, Benoit P, et al. Thromboxane A2 inhibition: therapeutic potential in bronchial asthma. Am J Respir Med. 2002;1(1):11-7. PMID: 14720071.

 

Ishiura Y, Fujimura M, Yamamori C, et al. Thromboxane antagonism and cough in chronic bronchitis. Ann Med. 2003;35(2):135-9. PMID: 12795341.

" Not dangerous goods.

LKT M3378 MitoPTTM JC-1 Assay kit 100 Tests 328.5 Cellular apoptosis measuring kit. MitoPTTM Ambient 4°C

LKT M3378 MitoPTTM JC-1 Assay kit 400 Tests 691 Cellular apoptosis measuring kit. MitoPTTM Ambient 4°C

LKT M3379 Mitoxantrone Dihydrochloride 50 mg 88.3 Anthracenedione, DNA intercalator; Pim-1 inhibitor. 1,4-dihydroxy-5,8-bis[[2-[(2-hydroxyethyl) amino]- ethyl] amino]-9,10-anthracenedione dihydrochloride Mitoxantrone hydrochloride; Novantrone 70476-82-3 ≥98% 517.41 C22H28N4O6 2HCl C1=CC(=C2C(=C1NCCNCCO)C(=O)C3=C(C=CC(=C3C2=O)O)O)NCCNCCO.Cl.Cl Ambient Ambient Soluble in water. "Pendleton M, Lindsey RH Jr, Felix CA, et al. Topoisomerase II and leukemia. Ann N Y Acad Sci. 2014 Mar;1310:98-110. PMID: 24495080.

 

Wan X, Zhang W, Li L, et al. A new target for an old drug: identifying mitoxantrone as a nanomolar inhibitor of PIM1 kinase via kinome-wide selectivity modeling. J Med Chem. 2013 Mar 28;56(6):2619-29. PMID: 23442188.

 

Parker C, Waters R, Leighton C, et al. Effect of mitoxantrone on outcome of children with first relapse of acute lymphoblastic leukaemia (ALL R3): an open-label randomised trial. Lancet. 2010 Dec 11;376(9757):2009-17. PMID: 21131038.

 

Mazerski J, Martelli S, Borowski E. The geometry of intercalation complex of antitumor mitoxantrone and ametantrone with DNA: molecular dynamics simulations. Acta Biochim Pol. 1998;45(1):1-11. PMID: 9701490.

" T Not dangerous goods.

LKT M3379 Mitoxantrone Dihydrochloride 100 mg 163.2 Anthracenedione, DNA intercalator; Pim-1 inhibitor. 1,4-dihydroxy-5,8-bis[[2-[(2-hydroxyethyl) amino]- ethyl] amino]-9,10-anthracenedione dihydrochloride Mitoxantrone hydrochloride; Novantrone 70476-82-3 ≥98% 517.41 C22H28N4O6 2HCl C1=CC(=C2C(=C1NCCNCCO)C(=O)C3=C(C=CC(=C3C2=O)O)O)NCCNCCO.Cl.Cl Ambient Ambient Soluble in water. "Pendleton M, Lindsey RH Jr, Felix CA, et al. Topoisomerase II and leukemia. Ann N Y Acad Sci. 2014 Mar;1310:98-110. PMID: 24495080.

 

Wan X, Zhang W, Li L, et al. A new target for an old drug: identifying mitoxantrone as a nanomolar inhibitor of PIM1 kinase via kinome-wide selectivity modeling. J Med Chem. 2013 Mar 28;56(6):2619-29. PMID: 23442188.

 

Parker C, Waters R, Leighton C, et al. Effect of mitoxantrone on outcome of children with first relapse of acute lymphoblastic leukaemia (ALL R3): an open-label randomised trial. Lancet. 2010 Dec 11;376(9757):2009-17. PMID: 21131038.

 

Mazerski J, Martelli S, Borowski E. The geometry of intercalation complex of antitumor mitoxantrone and ametantrone with DNA: molecular dynamics simulations. Acta Biochim Pol. 1998;45(1):1-11. PMID: 9701490.

" T Not dangerous goods.

LKT M3379 Mitoxantrone Dihydrochloride 500 mg 611.5 Anthracenedione, DNA intercalator; Pim-1 inhibitor. 1,4-dihydroxy-5,8-bis[[2-[(2-hydroxyethyl) amino]- ethyl] amino]-9,10-anthracenedione dihydrochloride Mitoxantrone hydrochloride; Novantrone 70476-82-3 ≥98% 517.41 C22H28N4O6 2HCl C1=CC(=C2C(=C1NCCNCCO)C(=O)C3=C(C=CC(=C3C2=O)O)O)NCCNCCO.Cl.Cl Ambient Ambient Soluble in water. "Pendleton M, Lindsey RH Jr, Felix CA, et al. Topoisomerase II and leukemia. Ann N Y Acad Sci. 2014 Mar;1310:98-110. PMID: 24495080.

 

Wan X, Zhang W, Li L, et al. A new target for an old drug: identifying mitoxantrone as a nanomolar inhibitor of PIM1 kinase via kinome-wide selectivity modeling. J Med Chem. 2013 Mar 28;56(6):2619-29. PMID: 23442188.

 

Parker C, Waters R, Leighton C, et al. Effect of mitoxantrone on outcome of children with first relapse of acute lymphoblastic leukaemia (ALL R3): an open-label randomised trial. Lancet. 2010 Dec 11;376(9757):2009-17. PMID: 21131038.

 

Mazerski J, Martelli S, Borowski E. The geometry of intercalation complex of antitumor mitoxantrone and ametantrone with DNA: molecular dynamics simulations. Acta Biochim Pol. 1998;45(1):1-11. PMID: 9701490.

" T Not dangerous goods.

LKT M3453 Minoxidil 100 mg 67.9 NO donor; AR antagonist. "6-(1-Piperidinyl)-2,4-pyrimidinediamine 3-oxide 

" Alopexil; Loniten; Minoximen; Normoxidil; Regaine; Rogaine Tricoxidil 38304-91-5 ≥98% 209.25 C9H15N5O C1CCN(CC1)C2=NC(=N)N(C(=C2)N)O Ambient Ambient Soluble in propylene glycol, methanol or ethanol. Slightly soluble in water. "Hsu CL, Liu JS, Lin AC, et al. Minoxidil may suppress androgen receptor-related functions. Oncotarget. 2014 Apr 30;5(8):2187-97. PMID: 24742982.

 

Rossi A, Cantisani C, Melis L, et al. Minoxidil use in dermatology, side effects and recent patents. Recent Pat Inflamm Allergy Drug Discov. 2012 May;6(2):130-6. PMID: 22409453.

" Xn Xi Not dangerous goods.

LKT M3453 Minoxidil 500 mg 271.7 NO donor; AR antagonist. "6-(1-Piperidinyl)-2,4-pyrimidinediamine 3-oxide 

" Alopexil; Loniten; Minoximen; Normoxidil; Regaine; Rogaine Tricoxidil 38304-91-5 ≥98% 209.25 C9H15N5O C1CCN(CC1)C2=NC(=N)N(C(=C2)N)O Ambient Ambient Soluble in propylene glycol, methanol or ethanol. Slightly soluble in water. "Hsu CL, Liu JS, Lin AC, et al. Minoxidil may suppress androgen receptor-related functions. Oncotarget. 2014 Apr 30;5(8):2187-97. PMID: 24742982.

 

Rossi A, Cantisani C, Melis L, et al. Minoxidil use in dermatology, side effects and recent patents. Recent Pat Inflamm Allergy Drug Discov. 2012 May;6(2):130-6. PMID: 22409453.

" Xn Xi Not dangerous goods.

LKT M3453 Minoxidil 1 g 373.7 NO donor; AR antagonist. "6-(1-Piperidinyl)-2,4-pyrimidinediamine 3-oxide 

" Alopexil; Loniten; Minoximen; Normoxidil; Regaine; Rogaine Tricoxidil 38304-91-5 ≥98% 209.25 C9H15N5O C1CCN(CC1)C2=NC(=N)N(C(=C2)N)O Ambient Ambient Soluble in propylene glycol, methanol or ethanol. Slightly soluble in water. "Hsu CL, Liu JS, Lin AC, et al. Minoxidil may suppress androgen receptor-related functions. Oncotarget. 2014 Apr 30;5(8):2187-97. PMID: 24742982.

 

Rossi A, Cantisani C, Melis L, et al. Minoxidil use in dermatology, side effects and recent patents. Recent Pat Inflamm Allergy Drug Discov. 2012 May;6(2):130-6. PMID: 22409453.

" Xn Xi Not dangerous goods.

LKT M3476 Mithramycin 1 mg 56.3 Polyketide; DNMT 1 inhibitor, RNA synthesis inhibitor. Plicamycin, Mithramycin A 18378-89-7 ≥95% 1084.47 C52H76O25 CC1C(C(CC(O1)OC2CC(OC(C2O)C)OC3=CC4=CC5=C(C(=O)C(C(C5)C(C(=O)C(C(C)O)O)OC)OC6CC(C(C(O6)C)O)OC7CC(C(C(O7)C)O)OC8CC(C(C(O8)C)O)(C)O)C(=C4C(=C3C)O)O)O)O Ambient 4°C DMSO, Methanol, Ethanol "Choi ES, Chung T, Kim JS, et al. Mithramycin A induces apoptosis by regulating the mTOR/Mcl-1/tBid pathway in androgen-independent prostate cancer cells. J Clin Biochem Nutr. 2013 Sep;53(2):89-93. PMID: 24062605.

 

Choi ES, Jung JY, Lee JS, et al. Myeloid cell leukemia-1 is a key molecular target for mithramycin A-induced apoptosis in androgen-independent prostate cancer cells and a tumor xenograft animal model. Cancer Lett. 2013 Jan 1;328(1):65-72. PMID: 23000424.

 

Lin RK, Hsu CH, Wang YC. Mithramycin A inhibits DNA methyltransferase and metastasis potential of lung cancer cells. Anticancer Drugs. 2007 Nov;18(10):1157-64. PMID: 17893516.

 

Ferrante RJ, Ryu H, Kubilus JK, et al. Chemotherapy for the brain: the antitumor antibiotic mithramycin prolongs survival in a mouse model of Huntington's disease. J Neurosci. 2004 Nov 17;24(46):10335-42. PMID: 15548647.

 

Miller DM, Polansky DA, Thomas SD, et al. Mithramycin selectively inhibits transcription of G-C containing DNA. Am J Med Sci. 1987 Nov;294(5):388-94. PMID: 2962490.

" Xn Not dangerous goods.

LKT M3476 Mithramycin 5 mg 225 Polyketide; DNMT 1 inhibitor, RNA synthesis inhibitor. Plicamycin, Mithramycin A 18378-89-7 ≥95% 1084.47 C52H76O25 CC1C(C(CC(O1)OC2CC(OC(C2O)C)OC3=CC4=CC5=C(C(=O)C(C(C5)C(C(=O)C(C(C)O)O)OC)OC6CC(C(C(O6)C)O)OC7CC(C(C(O7)C)O)OC8CC(C(C(O8)C)O)(C)O)C(=C4C(=C3C)O)O)O)O Ambient 4°C DMSO, Methanol, Ethanol "Choi ES, Chung T, Kim JS, et al. Mithramycin A induces apoptosis by regulating the mTOR/Mcl-1/tBid pathway in androgen-independent prostate cancer cells. J Clin Biochem Nutr. 2013 Sep;53(2):89-93. PMID: 24062605.

 

Choi ES, Jung JY, Lee JS, et al. Myeloid cell leukemia-1 is a key molecular target for mithramycin A-induced apoptosis in androgen-independent prostate cancer cells and a tumor xenograft animal model. Cancer Lett. 2013 Jan 1;328(1):65-72. PMID: 23000424.

 

Lin RK, Hsu CH, Wang YC. Mithramycin A inhibits DNA methyltransferase and metastasis potential of lung cancer cells. Anticancer Drugs. 2007 Nov;18(10):1157-64. PMID: 17893516.

 

Ferrante RJ, Ryu H, Kubilus JK, et al. Chemotherapy for the brain: the antitumor antibiotic mithramycin prolongs survival in a mouse model of Huntington's disease. J Neurosci. 2004 Nov 17;24(46):10335-42. PMID: 15548647.

 

Miller DM, Polansky DA, Thomas SD, et al. Mithramycin selectively inhibits transcription of G-C containing DNA. Am J Med Sci. 1987 Nov;294(5):388-94. PMID: 2962490.

" Xn Not dangerous goods.

LKT M3476 Mithramycin 10 mg 412.5 Polyketide; DNMT 1 inhibitor, RNA synthesis inhibitor. Plicamycin, Mithramycin A 18378-89-7 ≥95% 1084.47 C52H76O25 CC1C(C(CC(O1)OC2CC(OC(C2O)C)OC3=CC4=CC5=C(C(=O)C(C(C5)C(C(=O)C(C(C)O)O)OC)OC6CC(C(C(O6)C)O)OC7CC(C(C(O7)C)O)OC8CC(C(C(O8)C)O)(C)O)C(=C4C(=C3C)O)O)O)O Ambient 4°C DMSO, Methanol, Ethanol "Choi ES, Chung T, Kim JS, et al. Mithramycin A induces apoptosis by regulating the mTOR/Mcl-1/tBid pathway in androgen-independent prostate cancer cells. J Clin Biochem Nutr. 2013 Sep;53(2):89-93. PMID: 24062605.

 

Choi ES, Jung JY, Lee JS, et al. Myeloid cell leukemia-1 is a key molecular target for mithramycin A-induced apoptosis in androgen-independent prostate cancer cells and a tumor xenograft animal model. Cancer Lett. 2013 Jan 1;328(1):65-72. PMID: 23000424.

 

Lin RK, Hsu CH, Wang YC. Mithramycin A inhibits DNA methyltransferase and metastasis potential of lung cancer cells. Anticancer Drugs. 2007 Nov;18(10):1157-64. PMID: 17893516.

 

Ferrante RJ, Ryu H, Kubilus JK, et al. Chemotherapy for the brain: the antitumor antibiotic mithramycin prolongs survival in a mouse model of Huntington's disease. J Neurosci. 2004 Nov 17;24(46):10335-42. PMID: 15548647.

 

Miller DM, Polansky DA, Thomas SD, et al. Mithramycin selectively inhibits transcription of G-C containing DNA. Am J Med Sci. 1987 Nov;294(5):388-94. PMID: 2962490.

" Xn Not dangerous goods.

LKT S1848 Se-Methylseleno-L-cysteine 100 mg 139.3 Found in plants in Astragalus, Allium, and Brassica families. 3-(methylseleno)-L-alanine Methylselenocysteine; Selenium-methylselenocystine; 2-Amino-3-methylselenyl propionic acid 26046-90-2 ≥98% 182.08 C4H9NO2Se C[Se]CC(C(=O)O)N Ambient Ambient "Cao S, Durrani FA, Tóth K, et al. Se-methylselenocysteine offers selective protection against toxicity and potentiates the antitumour activity of anticancer drugs in preclinical animal models. Br J Cancer. 2014 Apr 2;110(7):1733-43. PMID: 24619073.

 

Shin HS, Yang WJ, Choi EM. The preventive effect of Se-methylselenocysteine on γ-radiation-induced oxidative stress in rat lungs. J Trace Elem Med Biol. 2013 Apr;27(2):154-9. PMID: 23176811.

 

Bhattacharya A. Methylselenocysteine: a promising antiangiogenic agent for overcoming drug delivery barriers in solid malignancies for therapeutic synergy with anticancer drugs. Expert Opin Drug Deliv. 2011 Jun;8(6):749-63. PMID: 21473705.

 

Pan MH, Hong HM, Lin CL, et al. Se-methylselenocysteine inhibits lipopolysaccharide-induced NF-κB activation and iNOS induction in RAW 264.7 murine macrophages. Mol Nutr Food Res. 2011 May;55(5):723-32. PMID: 21213327.

 

Zhang J, Wang L, Anderson LB, et al. Proteomic profiling of potential molecular targets of methyl-selenium compounds in the transgenic adenocarcinoma of mouse prostate model. Cancer Prev Res (Phila). 2010 Aug;3(8):994-1006. PMID: 20647336.

" T, N "UN number: 3283     Class: 6.1     Packing Group: III

Proper shipping name: Selenium compound, solid, n.o.s (Se-methylseleno-L-cysteine)"

LKT S1848 Se-Methylseleno-L-cysteine 250 mg 278.7 Found in plants in Astragalus, Allium, and Brassica families. 3-(methylseleno)-L-alanine Methylselenocysteine; Selenium-methylselenocystine; 2-Amino-3-methylselenyl propionic acid 26046-90-2 ≥98% 182.08 C4H9NO2Se C[Se]CC(C(=O)O)N Ambient Ambient "Cao S, Durrani FA, Tóth K, et al. Se-methylselenocysteine offers selective protection against toxicity and potentiates the antitumour activity of anticancer drugs in preclinical animal models. Br J Cancer. 2014 Apr 2;110(7):1733-43. PMID: 24619073.

 

Shin HS, Yang WJ, Choi EM. The preventive effect of Se-methylselenocysteine on γ-radiation-induced oxidative stress in rat lungs. J Trace Elem Med Biol. 2013 Apr;27(2):154-9. PMID: 23176811.

 

Bhattacharya A. Methylselenocysteine: a promising antiangiogenic agent for overcoming drug delivery barriers in solid malignancies for therapeutic synergy with anticancer drugs. Expert Opin Drug Deliv. 2011 Jun;8(6):749-63. PMID: 21473705.

 

Pan MH, Hong HM, Lin CL, et al. Se-methylselenocysteine inhibits lipopolysaccharide-induced NF-κB activation and iNOS induction in RAW 264.7 murine macrophages. Mol Nutr Food Res. 2011 May;55(5):723-32. PMID: 21213327.

 

Zhang J, Wang L, Anderson LB, et al. Proteomic profiling of potential molecular targets of methyl-selenium compounds in the transgenic adenocarcinoma of mouse prostate model. Cancer Prev Res (Phila). 2010 Aug;3(8):994-1006. PMID: 20647336.

" T, N "UN number: 3283     Class: 6.1     Packing Group: III

Proper shipping name: Selenium compound, solid, n.o.s (Se-methylseleno-L-cysteine)"

LKT M3576 Mitotane 100 mg 48.5 Diphenylmethane, inhibits secretion of cortisol. 53-19-0 ≥98% 320.04 C14H10Cl4 C1=CC=C(C(=C1)C(C2=CC=C(C=C2)Cl)C(Cl)Cl)Cl Ambient Ambient "Shawa H, Deniz F, Bazerbashi H, et al. Mitotane-induced hyperlipidemia: a retrospective cohort study. Int J Endocrinol. 2013;2013:624962. PMID: 24348556.

 

Hescot S, Slama A, Lombès A, et al. Mitotane alters mitochondrial respiratory chain activity by inducing cytochrome c oxidase defect in human adrenocortical cells. Endocr Relat Cancer. 2013 May 21;20(3):371-81. PMID: 23696597.

 

Fang VS. Cytotoxic activity of 1-(o-chlorophenyl)-1-(p-chlorophenyl)-2,2-dichloroethane (mitotane) and its analogs on feminizing adrenal neoplastic cells in culture. Cancer Res. 1979 Jan;39(1):139-45. PMID: 761184.

" Xn Not dangerous goods.

LKT M3576 Mitotane 500 mg 97 Diphenylmethane, inhibits secretion of cortisol. 53-19-0 ≥98% 320.04 C14H10Cl4 C1=CC=C(C(=C1)C(C2=CC=C(C=C2)Cl)C(Cl)Cl)Cl Ambient Ambient "Shawa H, Deniz F, Bazerbashi H, et al. Mitotane-induced hyperlipidemia: a retrospective cohort study. Int J Endocrinol. 2013;2013:624962. PMID: 24348556.

 

Hescot S, Slama A, Lombès A, et al. Mitotane alters mitochondrial respiratory chain activity by inducing cytochrome c oxidase defect in human adrenocortical cells. Endocr Relat Cancer. 2013 May 21;20(3):371-81. PMID: 23696597.

 

Fang VS. Cytotoxic activity of 1-(o-chlorophenyl)-1-(p-chlorophenyl)-2,2-dichloroethane (mitotane) and its analogs on feminizing adrenal neoplastic cells in culture. Cancer Res. 1979 Jan;39(1):139-45. PMID: 761184.

" Xn Not dangerous goods.

LKT M3576 Mitotane 1 g 163.8 Diphenylmethane, inhibits secretion of cortisol. 53-19-0 ≥98% 320.04 C14H10Cl4 C1=CC=C(C(=C1)C(C2=CC=C(C=C2)Cl)C(Cl)Cl)Cl Ambient Ambient "Shawa H, Deniz F, Bazerbashi H, et al. Mitotane-induced hyperlipidemia: a retrospective cohort study. Int J Endocrinol. 2013;2013:624962. PMID: 24348556.

 

Hescot S, Slama A, Lombès A, et al. Mitotane alters mitochondrial respiratory chain activity by inducing cytochrome c oxidase defect in human adrenocortical cells. Endocr Relat Cancer. 2013 May 21;20(3):371-81. PMID: 23696597.

 

Fang VS. Cytotoxic activity of 1-(o-chlorophenyl)-1-(p-chlorophenyl)-2,2-dichloroethane (mitotane) and its analogs on feminizing adrenal neoplastic cells in culture. Cancer Res. 1979 Jan;39(1):139-45. PMID: 761184.

" Xn Not dangerous goods.

LKT M3577 Mitiglinide Calcium 100 mg 125.6 ATP-sensitive K+ channel blocker, potential RyR agonist. 145375-43-5 ≥98% 668.88 2(C19H24NO3)Ca C1CCC2CN(CC2C1)C(=O)CC(CC3=CC=CC=C3)C(=O)O Ambient Ambient "Phillippe HM, Wargo KA. Mitiglinide for type 2 diabetes treatment. Expert Opin Pharmacother. 2013 Oct;14(15):2133-44. PMID: 23992284.

 

Wang B, Yang G, Yang M, et al. Mitiglinide treatment may decreases plasma fibroblast growth factor-21 levels in individuals with new-onset T2DM. Cytokine. 2012 Feb;57(2):300-3. PMID: 22129626.

 

Phillippe HM, Wargo KA. Mitiglinide: a novel agent for the treatment of type 2 diabetes mellitus. Ann Pharmacother. 2010 Oct;44(10):1615-23. PMID: 20841518.

 

Shigeto M, Katsura M, Matsuda M, et al. Nateglinide and mitiglinide, but not sulfonylureas, induce insulin secretion through a mechanism mediated by calcium release from endoplasmic reticulum. J Pharmacol Exp Ther. 2007 Jul;322(1):1-7. PMID: 17409272.

" Not dangerous goods.

LKT M3577 Mitiglinide Calcium 250 mg 231.1 ATP-sensitive K+ channel blocker, potential RyR agonist. 145375-43-5 ≥98% 668.88 2(C19H24NO3)Ca C1CCC2CN(CC2C1)C(=O)CC(CC3=CC=CC=C3)C(=O)O Ambient Ambient "Phillippe HM, Wargo KA. Mitiglinide for type 2 diabetes treatment. Expert Opin Pharmacother. 2013 Oct;14(15):2133-44. PMID: 23992284.

 

Wang B, Yang G, Yang M, et al. Mitiglinide treatment may decreases plasma fibroblast growth factor-21 levels in individuals with new-onset T2DM. Cytokine. 2012 Feb;57(2):300-3. PMID: 22129626.

 

Phillippe HM, Wargo KA. Mitiglinide: a novel agent for the treatment of type 2 diabetes mellitus. Ann Pharmacother. 2010 Oct;44(10):1615-23. PMID: 20841518.

 

Shigeto M, Katsura M, Matsuda M, et al. Nateglinide and mitiglinide, but not sulfonylureas, induce insulin secretion through a mechanism mediated by calcium release from endoplasmic reticulum. J Pharmacol Exp Ther. 2007 Jul;322(1):1-7. PMID: 17409272.

" Not dangerous goods.

LKT M3577 Mitiglinide Calcium 1 g 736.8 ATP-sensitive K+ channel blocker, potential RyR agonist. 145375-43-5 ≥98% 668.88 2(C19H24NO3)Ca C1CCC2CN(CC2C1)C(=O)CC(CC3=CC=CC=C3)C(=O)O Ambient Ambient "Phillippe HM, Wargo KA. Mitiglinide for type 2 diabetes treatment. Expert Opin Pharmacother. 2013 Oct;14(15):2133-44. PMID: 23992284.

 

Wang B, Yang G, Yang M, et al. Mitiglinide treatment may decreases plasma fibroblast growth factor-21 levels in individuals with new-onset T2DM. Cytokine. 2012 Feb;57(2):300-3. PMID: 22129626.

 

Phillippe HM, Wargo KA. Mitiglinide: a novel agent for the treatment of type 2 diabetes mellitus. Ann Pharmacother. 2010 Oct;44(10):1615-23. PMID: 20841518.

 

Shigeto M, Katsura M, Matsuda M, et al. Nateglinide and mitiglinide, but not sulfonylureas, induce insulin secretion through a mechanism mediated by calcium release from endoplasmic reticulum. J Pharmacol Exp Ther. 2007 Jul;322(1):1-7. PMID: 17409272.

" Not dangerous goods.

LKT S1845 L-(+)-Selenomethionine 10 mg 32.3 Naturally occurring amino acid found in grains, nuts, legumes. (S)-2-amino-4-(methylseleno)-butanoic acid Selenium methionine; Selenomethionine 3211-76-5 ≥98% 196.11 C5H11NO2Se C[Se]CCC(C(=O)O)N Ambient -20°C Soluble in water. Slightly soluble in methanol. "Cassidy PB, Fain HD, Cassidy JP Jr, et al. Selenium for the prevention of cutaneous melanoma. Nutrients. 2013 Mar 7;5(3):725-49. PMID: 23470450.

 

Ware JH, Zhou Z, Romero-Weaver AL, et al. Effects of selenomethionine in irradiated human thyroid epithelial cells and tumorigenicity studies. Nutr Cancer. 2011;63(7):1114-21. PMID: 21916697.

 

Dennert G, Zwahlen M, Brinkman M, et al. Selenium for preventing cancer. Cochrane Database Syst Rev. 2011 May 11;(5):CD005195. Update in: Cochrane Database Syst Rev. 2014;3:CD005195.  PMID: 21563143.

" T, N "UN number: 3283     Class: 6.1     Packing Group: III

Proper shipping name: Selenium compound, solid, n.o.s (L-(+)_Selenomethionine)"

LKT S1845 L-(+)-Selenomethionine 25 mg 66.4 Naturally occurring amino acid found in grains, nuts, legumes. (S)-2-amino-4-(methylseleno)-butanoic acid Selenium methionine; Selenomethionine 3211-76-5 ≥98% 196.11 C5H11NO2Se C[Se]CCC(C(=O)O)N Ambient -20°C Soluble in water. Slightly soluble in methanol. "Cassidy PB, Fain HD, Cassidy JP Jr, et al. Selenium for the prevention of cutaneous melanoma. Nutrients. 2013 Mar 7;5(3):725-49. PMID: 23470450.

 

Ware JH, Zhou Z, Romero-Weaver AL, et al. Effects of selenomethionine in irradiated human thyroid epithelial cells and tumorigenicity studies. Nutr Cancer. 2011;63(7):1114-21. PMID: 21916697.

 

Dennert G, Zwahlen M, Brinkman M, et al. Selenium for preventing cancer. Cochrane Database Syst Rev. 2011 May 11;(5):CD005195. Update in: Cochrane Database Syst Rev. 2014;3:CD005195.  PMID: 21563143.

" T, N "UN number: 3283     Class: 6.1     Packing Group: III

Proper shipping name: Selenium compound, solid, n.o.s (L-(+)_Selenomethionine)"

LKT S1845 L-(+)-Selenomethionine 100 mg 220.1 Naturally occurring amino acid found in grains, nuts, legumes. (S)-2-amino-4-(methylseleno)-butanoic acid Selenium methionine; Selenomethionine 3211-76-5 ≥98% 196.11 C5H11NO2Se C[Se]CCC(C(=O)O)N Ambient -20°C Soluble in water. Slightly soluble in methanol. "Cassidy PB, Fain HD, Cassidy JP Jr, et al. Selenium for the prevention of cutaneous melanoma. Nutrients. 2013 Mar 7;5(3):725-49. PMID: 23470450.

 

Ware JH, Zhou Z, Romero-Weaver AL, et al. Effects of selenomethionine in irradiated human thyroid epithelial cells and tumorigenicity studies. Nutr Cancer. 2011;63(7):1114-21. PMID: 21916697.

 

Dennert G, Zwahlen M, Brinkman M, et al. Selenium for preventing cancer. Cochrane Database Syst Rev. 2011 May 11;(5):CD005195. Update in: Cochrane Database Syst Rev. 2014;3:CD005195.  PMID: 21563143.

" T, N "UN number: 3283     Class: 6.1     Packing Group: III

Proper shipping name: Selenium compound, solid, n.o.s (L-(+)_Selenomethionine)"

LKT M3584 Mivacurium Chloride 25 mg 90.1 Non-depolarizing NMJ blocker; nAChR antagonist. 106861-44-3 ≥98% 1100.18 C58H80N2O14Cl2 C[N+]1(CCC2=CC(=C(C=C2C1CC3=CC(=C(C(=C3)OC)OC)OC)OC)OC)CCCOC(=O)CCC=CCCC(=O)OCCC[N+]4(CCC5=CC(=C(C=C5C4CC6=CC(=C(C(=C6)OC)OC)OC)OC)OC)C.[Cl-].[Cl-] Ambient Ambient "Patterson E, Lu Z, Lin J, et al. Antifibrillatory properties of mivacurium in a canine model of atrial fibrillation. J Cardiovasc Pharmacol. 2008 Mar;51(3):293-303. PMID: 18356695.

 

Jonsson M, Gurley D, Dabrowski M, et al. Distinct pharmacologic properties of neuromuscular blocking agents on human neuronal nicotinic acetylcholine receptors: a possible explanation for the train-of-four fade. Anesthesiology. 2006 Sep;105(3):521-33. PMID: 16931985.

 

Feldman SA, Wu X, England A. Rate of 'onset' and 'offset' of four non-depolarising neuromuscular blocking drugs. Anaesthesia. 1995 Jun;50(6):510-3. PMID: 7618664.

" Not dangerous goods.

LKT M3584 Mivacurium Chloride 100 mg 281.2 Non-depolarizing NMJ blocker; nAChR antagonist. 106861-44-3 ≥98% 1100.18 C58H80N2O14Cl2 C[N+]1(CCC2=CC(=C(C=C2C1CC3=CC(=C(C(=C3)OC)OC)OC)OC)OC)CCCOC(=O)CCC=CCCC(=O)OCCC[N+]4(CCC5=CC(=C(C=C5C4CC6=CC(=C(C(=C6)OC)OC)OC)OC)OC)C.[Cl-].[Cl-] Ambient Ambient "Patterson E, Lu Z, Lin J, et al. Antifibrillatory properties of mivacurium in a canine model of atrial fibrillation. J Cardiovasc Pharmacol. 2008 Mar;51(3):293-303. PMID: 18356695.

 

Jonsson M, Gurley D, Dabrowski M, et al. Distinct pharmacologic properties of neuromuscular blocking agents on human neuronal nicotinic acetylcholine receptors: a possible explanation for the train-of-four fade. Anesthesiology. 2006 Sep;105(3):521-33. PMID: 16931985.

 

Feldman SA, Wu X, England A. Rate of 'onset' and 'offset' of four non-depolarising neuromuscular blocking drugs. Anaesthesia. 1995 Jun;50(6):510-3. PMID: 7618664.

" Not dangerous goods.

LKT M3584 Mivacurium Chloride 500 mg 883.3 Non-depolarizing NMJ blocker; nAChR antagonist. 106861-44-3 ≥98% 1100.18 C58H80N2O14Cl2 C[N+]1(CCC2=CC(=C(C=C2C1CC3=CC(=C(C(=C3)OC)OC)OC)OC)OC)CCCOC(=O)CCC=CCCC(=O)OCCC[N+]4(CCC5=CC(=C(C=C5C4CC6=CC(=C(C(=C6)OC)OC)OC)OC)OC)C.[Cl-].[Cl-] Ambient Ambient "Patterson E, Lu Z, Lin J, et al. Antifibrillatory properties of mivacurium in a canine model of atrial fibrillation. J Cardiovasc Pharmacol. 2008 Mar;51(3):293-303. PMID: 18356695.

 

Jonsson M, Gurley D, Dabrowski M, et al. Distinct pharmacologic properties of neuromuscular blocking agents on human neuronal nicotinic acetylcholine receptors: a possible explanation for the train-of-four fade. Anesthesiology. 2006 Sep;105(3):521-33. PMID: 16931985.

 

Feldman SA, Wu X, England A. Rate of 'onset' and 'offset' of four non-depolarising neuromuscular blocking drugs. Anaesthesia. 1995 Jun;50(6):510-3. PMID: 7618664.

" Not dangerous goods.

LKT S1843 L-Selectin 1 mg 211.2 Endogenous adhesion molecule, binds PKC, calmodulin. 126880-86-2 ≥95% 1426.75 C62H105N16O18S2 Ambient -20°C "Gaborski TR, Sealander MN, Waugh RE, et al. Dynamics of adhesion molecule domains on neutrophil membranes: surfing the dynamic cell topography. Eur Biophys J. 2013 Dec;42(11-12):851-5. PMID: 24113789.

 

Domínguez-Luis M, Herrera-García A, Arce-Franco M, et al. Superoxide anion mediates the L-selectin down-regulation induced by non-steroidal anti-inflammatory drugs in human neutrophils. Biochem Pharmacol. 2013 Jan 15;85(2):245-56. PMID: 23142710.

 

Deng W, Srinivasan S, Zheng X, et al. Interaction of calmodulin with L-selectin at the membrane interface: implication on the regulation of L-selectin shedding. J Mol Biol. 2011 Aug 5;411(1):220-33. PMID: 21664913.

 

Waddell TK, Fialkow L, Chan CK, et al. Potentiation of the oxidative burst of human neutrophils. A signaling role for L-selectin. J Biol Chem. 1994 Jul 15;269(28):18485-91. PMID: 7518434.

"

LKT S1843 L-Selectin 2 mg 359.9 Endogenous adhesion molecule, binds PKC, calmodulin. 126880-86-2 ≥95% 1426.75 C62H105N16O18S2 Ambient -20°C "Gaborski TR, Sealander MN, Waugh RE, et al. Dynamics of adhesion molecule domains on neutrophil membranes: surfing the dynamic cell topography. Eur Biophys J. 2013 Dec;42(11-12):851-5. PMID: 24113789.

 

Domínguez-Luis M, Herrera-García A, Arce-Franco M, et al. Superoxide anion mediates the L-selectin down-regulation induced by non-steroidal anti-inflammatory drugs in human neutrophils. Biochem Pharmacol. 2013 Jan 15;85(2):245-56. PMID: 23142710.

 

Deng W, Srinivasan S, Zheng X, et al. Interaction of calmodulin with L-selectin at the membrane interface: implication on the regulation of L-selectin shedding. J Mol Biol. 2011 Aug 5;411(1):220-33. PMID: 21664913.

 

Waddell TK, Fialkow L, Chan CK, et al. Potentiation of the oxidative burst of human neutrophils. A signaling role for L-selectin. J Biol Chem. 1994 Jul 15;269(28):18485-91. PMID: 7518434.

"

LKT S1843 L-Selectin 5 mg 633.9 Endogenous adhesion molecule, binds PKC, calmodulin. 126880-86-2 ≥95% 1426.75 C62H105N16O18S2 Ambient -20°C "Gaborski TR, Sealander MN, Waugh RE, et al. Dynamics of adhesion molecule domains on neutrophil membranes: surfing the dynamic cell topography. Eur Biophys J. 2013 Dec;42(11-12):851-5. PMID: 24113789.

 

Domínguez-Luis M, Herrera-García A, Arce-Franco M, et al. Superoxide anion mediates the L-selectin down-regulation induced by non-steroidal anti-inflammatory drugs in human neutrophils. Biochem Pharmacol. 2013 Jan 15;85(2):245-56. PMID: 23142710.

 

Deng W, Srinivasan S, Zheng X, et al. Interaction of calmodulin with L-selectin at the membrane interface: implication on the regulation of L-selectin shedding. J Mol Biol. 2011 Aug 5;411(1):220-33. PMID: 21664913.

 

Waddell TK, Fialkow L, Chan CK, et al. Potentiation of the oxidative burst of human neutrophils. A signaling role for L-selectin. J Biol Chem. 1994 Jul 15;269(28):18485-91. PMID: 7518434.

"

LKT M3598 Mizoribine Hydrobromide 10 mg 95.1 IMPDH inhibitor. 50924-49-7 ≥98% 340.13 C9H14BRN3O6 C1=NC(=C(N1C2C(C(C(O2)CO)O)O)O)C(=O)N Ambient Ambient "Sugiyama E, Ikemoto M, Taki H, et al. Mizoribine, an inhibitor of inosine monophosphate dehydrogenase, inhibits interleukin-6 production by freshly prepared rheumatoid synovial cells. Mod Rheumatol. 2001 Mar;11(1):28-33. PMID: 24387017.

 

Liu S, Xie Y, Lv Y, et al. A novel target of mizoribine inhibiting mesangial cell proliferation: S phase kinase-associated protein 2. Am J Nephrol. 2010;32(5):447-55. PMID: 20924167.

 

Rodriguez-Suarez R, Xu D, Veillette K, et al. Mechanism-of-action determination of GMP synthase inhibitors and target validation in Candida albicans and Aspergillus fumigatus. Chem Biol. 2007 Oct;14(10):1163-75. PMID: 17961828.

 

Zhong B, Tajima M, Takahara H, et al. Inhibitory effect of mizoribine on matrix metalloproteinase-1 production in synovial fibroblasts and THP-1 macrophages. Mod Rheumatol. 2005;15(4):264-8. PMID: 17029075.

 

Hedstrom L. IMP dehydrogenase: mechanism of action and inhibition. Curr Med Chem. 1999 Jul;6(7):545-60. PMID: 10390600.

" T Not dangerous goods.

LKT M3598 Mizoribine Hydrobromide 25 mg 163.2 IMPDH inhibitor. 50924-49-7 ≥98% 340.13 C9H14BRN3O6 C1=NC(=C(N1C2C(C(C(O2)CO)O)O)O)C(=O)N Ambient Ambient "Sugiyama E, Ikemoto M, Taki H, et al. Mizoribine, an inhibitor of inosine monophosphate dehydrogenase, inhibits interleukin-6 production by freshly prepared rheumatoid synovial cells. Mod Rheumatol. 2001 Mar;11(1):28-33. PMID: 24387017.

 

Liu S, Xie Y, Lv Y, et al. A novel target of mizoribine inhibiting mesangial cell proliferation: S phase kinase-associated protein 2. Am J Nephrol. 2010;32(5):447-55. PMID: 20924167.

 

Rodriguez-Suarez R, Xu D, Veillette K, et al. Mechanism-of-action determination of GMP synthase inhibitors and target validation in Candida albicans and Aspergillus fumigatus. Chem Biol. 2007 Oct;14(10):1163-75. PMID: 17961828.

 

Zhong B, Tajima M, Takahara H, et al. Inhibitory effect of mizoribine on matrix metalloproteinase-1 production in synovial fibroblasts and THP-1 macrophages. Mod Rheumatol. 2005;15(4):264-8. PMID: 17029075.

 

Hedstrom L. IMP dehydrogenase: mechanism of action and inhibition. Curr Med Chem. 1999 Jul;6(7):545-60. PMID: 10390600.

" T Not dangerous goods.

LKT M3598 Mizoribine Hydrobromide 100 mg 638.7 IMPDH inhibitor. 50924-49-7 ≥98% 340.13 C9H14BRN3O6 C1=NC(=C(N1C2C(C(C(O2)CO)O)O)O)C(=O)N Ambient Ambient "Sugiyama E, Ikemoto M, Taki H, et al. Mizoribine, an inhibitor of inosine monophosphate dehydrogenase, inhibits interleukin-6 production by freshly prepared rheumatoid synovial cells. Mod Rheumatol. 2001 Mar;11(1):28-33. PMID: 24387017.

 

Liu S, Xie Y, Lv Y, et al. A novel target of mizoribine inhibiting mesangial cell proliferation: S phase kinase-associated protein 2. Am J Nephrol. 2010;32(5):447-55. PMID: 20924167.

 

Rodriguez-Suarez R, Xu D, Veillette K, et al. Mechanism-of-action determination of GMP synthase inhibitors and target validation in Candida albicans and Aspergillus fumigatus. Chem Biol. 2007 Oct;14(10):1163-75. PMID: 17961828.

 

Zhong B, Tajima M, Takahara H, et al. Inhibitory effect of mizoribine on matrix metalloproteinase-1 production in synovial fibroblasts and THP-1 macrophages. Mod Rheumatol. 2005;15(4):264-8. PMID: 17029075.

 

Hedstrom L. IMP dehydrogenase: mechanism of action and inhibition. Curr Med Chem. 1999 Jul;6(7):545-60. PMID: 10390600.

" T Not dangerous goods.

LKT S1810 Secnidazole 5 g 69.3 Nitroimidazole, binds DNA; nucleic acid synthesis inhibitor. α,2-Dimethyl-5-nitro-1H-imidazole-1-ethanol Flagentyl 3366-95-8 ≥98% 185.18 C7H11N3O3 CC1=NC=C(N1CC(C)O)[N+](=O)[O-] Ambient Ambient Soluble in water. "Almirall P, Escobedo AA, Ayala I, et al. Mebendazole compared with secnidazole in the treatment of adult giardiasis: a randomised, no-inferiority, open clinical trial. J Parasitol Res. 2011;2011:636857. PMID: 22174992.

 

De Backer E, Dubreuil L, Brauman M, et al. In vitro activity of secnidazole against Atopobium vaginae, an anaerobic pathogen involved in bacterial vaginosis. Clin Microbiol Infect. 2010 May;16(5):470-2. PMID: 19548924.

" Not dangerous goods.

LKT S1810 Secnidazole 10 g 104.3 Nitroimidazole, binds DNA; nucleic acid synthesis inhibitor. α,2-Dimethyl-5-nitro-1H-imidazole-1-ethanol Flagentyl 3366-95-8 ≥98% 185.18 C7H11N3O3 CC1=NC=C(N1CC(C)O)[N+](=O)[O-] Ambient Ambient Soluble in water. "Almirall P, Escobedo AA, Ayala I, et al. Mebendazole compared with secnidazole in the treatment of adult giardiasis: a randomised, no-inferiority, open clinical trial. J Parasitol Res. 2011;2011:636857. PMID: 22174992.

 

De Backer E, Dubreuil L, Brauman M, et al. In vitro activity of secnidazole against Atopobium vaginae, an anaerobic pathogen involved in bacterial vaginosis. Clin Microbiol Infect. 2010 May;16(5):470-2. PMID: 19548924.

" Not dangerous goods.

LKT S1810 Secnidazole 25 g 173.3 Nitroimidazole, binds DNA; nucleic acid synthesis inhibitor. α,2-Dimethyl-5-nitro-1H-imidazole-1-ethanol Flagentyl 3366-95-8 ≥98% 185.18 C7H11N3O3 CC1=NC=C(N1CC(C)O)[N+](=O)[O-] Ambient Ambient Soluble in water. "Almirall P, Escobedo AA, Ayala I, et al. Mebendazole compared with secnidazole in the treatment of adult giardiasis: a randomised, no-inferiority, open clinical trial. J Parasitol Res. 2011;2011:636857. PMID: 22174992.

 

De Backer E, Dubreuil L, Brauman M, et al. In vitro activity of secnidazole against Atopobium vaginae, an anaerobic pathogen involved in bacterial vaginosis. Clin Microbiol Infect. 2010 May;16(5):470-2. PMID: 19548924.

" Not dangerous goods.

LKT M5675 Motilin, dog 0.5 mg 204.1 Endogenous peptide hormone; motilin agonist. 85490-53-5 ≥95% 2685.1 C120H194N36O34 CCC(C)C(C(=O)NC(CC1=CC=CC=C1)C(=O)NC(C(C)O)C(=O)NC(CC2=CNC=N2)C(=O)NC(CO)C(=O)NC(CCC(=O)O)C(=O)NC(CC(C)C)C(=O)NC(CCC(=O)N)C(=O)NC(CCCCN)C(=O)NC(C(C)CC)C(=O)NC(CCCNC(=N)N)C(=O)NC(CCC(=O)O)C(=O)NC(CCCCN)C(=O)NC(CCC(=O)O)C(=O)NC(CCCNC(=N)N)C(=O)NC(CC(=O)N)C(=O)NC(CCCCN)C(=O)NCC(=O)NC(CCC(=O)N)C(=O)O)NC(=O)C3CCCN3C(=O)C(C(C)C)NC(=O)C(CC4=CC=CC=C4)N Ambient -20°C "Sanger GJ, Wang Y, Hobson A, et al. Motilin: towards a new understanding of the gastrointestinal neuropharmacology and therapeutic use of motilin receptor agonists. Br J Pharmacol. 2013 Dec;170(7):1323-32. PMID: 23189978.

 

Feng B, Liu JC, Zhang J, et al. Anxiolytic actions of motilin in the basolateral amygdala. Mol Neurobiol. 2013 Jun;47(3):892-902. PMID: 23307330.

 

Miegueu P, Cianflone K, Richard D, et al. Motilin stimulates preadipocyte proliferation and differentiation and adipocyte lipid storage. Am J Physiol Endocrinol Metab. 2011 Nov;301(5):E758-66. PMID: 21771971.

 

Piche T, Galmiche JP. Pharmacological targets in gastro-oesophageal reflux disease. Basic Clin Pharmacol Toxicol. 2005 Dec;97(6):333-41. PMID: 16364047.

" Not dangerous goods.

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