详细介绍
品牌 | 其他品牌 | 供货周期 | 现货 |
---|---|---|---|
应用领域 | 医疗卫生,食品,化工,生物产业,制药 |
Mediomics公司于2001年创立于美国密苏里州,致力于为科研机构、即时检测、医药企业以及医疗和环境研究市场提供创新的和生物传感器等产品,其可以简单快速的定量检测生物学和临床相关的大分子物质,包括DNA、生物标志物、激素、抗体、细胞内信号分子、蛋白质复合物、细菌、真菌和病毒等。
Mediomics目前拥有四个核心专有技术:
1. Bridge-It®:一种快速灵敏的DNA-蛋白质结合物检测平台
Bridge-It®系列试剂盒可用来检测DNA结合蛋白及其配体和共调节因子。该系列试剂盒基于一个简单的实验原理:一段针对已知蛋白的具有序列特异DNA结合位点的DNA双链被分为两段,每段含有一个短的单链突出端。这些突出端很短,因此没有靶蛋白时他们不会自发的重新结合。当靶蛋白出现时,靶蛋白与完整的DNA序列结合位点的高亲和力使得两段DNA双链重新结合。通过在每段位点加入适当的荧光探针就可以检测到该结合。然后用荧光共振能量转移技术(fluorescence resonance energy transfer,FRET)检测荧光信号的变化来判断DNA结合蛋白或其配体。
该系列试剂盒具有以下特色:
1) 简单的混合和测试方法:只需要混合样本和反应试剂,不需要其他操作技术。直接检测样本无需稀释步骤,只需混合样本/标准品和反应试剂。
2) 快速:孵育30min后即可检测荧光信号。
3) 定量检测
4) 可重复性好:实验变异性小,避免了抗体或放射性探针带来的批次间的差异。
5) 可实现高通量筛选
2. PINCER®:一种快速的生物传感器、生物测定和生物芯片平台
PINCER® Assays是一种用于定量检测生物样本中的生物标志物、细胞和病原体浓度的*的技术。该系列产品分为FRET-PINCER® Assay和TRF-PINCER® Assay两种,分别使用荧光共振能量转移技术(fluorescence resonance energy transfer,FRET)和时间分辨荧光(Time-Resolved Fluorometry,TRF)方法检测。其检测原理是:带有荧光探针的抗体由一个灵活的连接物通过互补的单链DNA突出端与DNA双链化学结合,这些突出端使得两个DNA片段有结合的可能性,然而在没有靶蛋白的情况下,两个DNA片段结合的可能性极小。当存在靶蛋白时,与PINCER试剂结合的靶蛋白将促使互补DNA单链突出端的结合而形成双链DNA。这种紧密稳定的结合使荧光团聚合起来,发生荧光共振能量转移。因此,检测样本发出的荧光能量水平或亮度的变化即可定量靶蛋白的浓度。
PINCER® Assay系列试剂盒的特色:
1) 简便:混合样本/标准品与分析试剂在室温孵育
2) 快速:孵育30min后检测荧光信号
3) 检测范围广:直接检测样本,无需稀释步骤
4) 兼容性:与大多数荧光读数仪兼容
5) 可实现高通量筛选
3. 使用创新技术筛选和研发可用于科研、临床诊断和治疗的新型高亲和力捕获试剂。
4. 抗血管生成相关疗法
这些技术已被证实适于检测一系列关键大分子物质,包括cAMP、、S-腺苷蛋氨酸、磷酸二酯酶、、胰岛素、C肽、白蛋白、C反应蛋白、IgG、IgM和大肠杆菌等等。
Mediomics HITR1011-100 hIgG TRF 100 dry ice Store all at -20ºC until use ¥2,975.00
Mediomics CHTR1008-100 hCRP TRF 100 dry ice Store all at -20ºC until use ¥2,975.00
Mediomics CHTR1008-384 hCRP TRF 384 dry ice Store all at -20ºC until use ¥8,500.00
Mediomics CHTR1021-50 hCRP TRF 50 dry ice Store all at -20ºC until use ¥3,740.00
Mediomics CHTR1021-96 hCRP TRF 96 dry ice Store all at -20ºC until use ¥6,800.00
Mediomics AHTR1016-96 hAlbumin TRF 96 dry ice Store all at -20ºC until use ¥6,800.00
Mediomics AHTR1016-50 hAlbumin TRF 50 dry ice Store all at -20ºC until use ¥3,740.00
Mediomics AHTR1005-100 hAlbumin TRF 100 dry ice Store all at -20ºC until use ¥2,975.00
Mediomics AHTR1005-384 hAlbumin TRF 384 dry ice Store all at -20ºC until use ¥8,500.00
Mediomics BTTR-1006-100 Biotin TRF 100 dry ice Store all at -20ºC until use ¥2,975.00
Mediomics BTTR-1006-384 Biotin TRF 384 dry ice Store all at -20ºC until use ¥8,500.00
Mediomics RI1015-100 rIgG FRET 100 dry ice Store all at -20ºC until use ¥2,550.00
Mediomics IH1017-96 hInsulin FRET 96 dry ice Store all at -20ºC until use ¥6,375.00
Mediomics RI1015-384 rIgG FRET 384 dry ice Store all at -20ºC until use ¥7,650.00
Mediomics IH1017-50 hInsulin FRET 50 dry ice Store all at -20ºC until use ¥3,400.00
Mediomics IH1010-100 hInsulin FRET 100 dry ice Store all at -20ºC until use ¥2,550.00
Mediomics IH1010-384 hInsulin FRET 384 dry ice Store all at -20ºC until use ¥7,650.00
Mediomics CH1021-50 hCRP FRET 50 dry ice Store all at -20ºC until use ¥3,400.00
Mediomics CH1021-96 hCRP FRET 96 dry ice Store all at -20ºC until use ¥6,375.00
Mediomics IMTR1009-384 mIgM TRF 384 dry ice Store all at -20ºC until use ¥8,500.00
Mediomics IMTR1009-100 mIgM TRF 100 dry ice Store all at -20ºC until use ¥2,975.00
Mediomics PM-803262-100 µg Recombinant human methionine aminopeptidase-2 dry ice Store at -20ºC ¥30,600.00
Mediomics PAB-503208 Anti-recombinant human MetAP-2 (full-length) Polyclonal Antibody dry ice Store at -20ºC ¥4,760.00
Mediomics PAB-503209 Anti-hMetAP-2 (C-terminal) Polyclonal Antibody dry ice Store at 4ºC ¥4,760.00
Mediomics 122937 10X KRB-IBMX Buffer dry ice Store at -20ºC ¥425.00
Mediomics 122934 Bridge-It cAMP 50 dry ice Store all at -20ºC until use ¥3,400.00
Mediomics 122935 Bridge-It cAMP 96 dry ice Store all at -20ºC until use ¥6,375.00
Mediomics 122939 Bridge-It cAMP 100 dry ice Store all at -20ºC until use ¥2,975.00
Mediomics 122938 Bridge-It cAMP 384 dry ice Store all at -20ºC until use ¥8,415.00
Mediomics 1-1-1002A Bridge-It L-Tryptophan 100 dry ice Store all at -20ºC until use ¥2,975.00
Mediomics 1-1-1002B Bridge-It L-Tryptophan 384 dry ice Store all at -20ºC until use ¥8,415.00
Mediomics 1-1-1005A Bridge-It L-MET 50 dry ice Store all at -20ºC until use ¥3,400.00
Mediomics 1-1-1005B Bridge-It L-MET 96 dry ice Store all at -20ºC until use ¥6,375.00
Mediomics 1-1-1006A Bridge-It L-MET 100 dry ice Store all at -20ºC until use ¥2,975.00
Mediomics 1-1-1006B Bridge-It L-MET 384 dry ice Store all at -20ºC until use ¥8,415.00
Mediomics 1-1-1003B Bridge-It SAM 96 dry ice Store all at -20ºC until use ¥6,375.00
Mediomics 1-1-1003A Bridge-It SAM 50 dry ice Store all at -20ºC until use ¥3,400.00
Mediomics 1-1-1004A Bridge-It SAM 100 dry ice Store all at -20ºC until use ¥2,975.00
Mediomics 1-1-1004B Bridge-It SAM 384 dry ice Store all at -20ºC until use ¥8,415.00
Mediomics PD1016-60 Bridge-It cAMP-PDE 60 dry ice Store all at -20ºC until use ¥3,400.00
Mediomics PD1016-96 Bridge-It cAMP-PDE 96 dry ice Store all at -20ºC until use ¥6,375.00
Mediomics PD1007-100 Bridge-It cAMP-PDE 100 dry ice Store all at -20ºC until use ¥2,975.00
Mediomics PD1007-384 Bridge-It cAMP-PDE 384 dry ice Store all at -20ºC until use ¥8,415.00
Mediomics IHTR1010-384 hInsulin TRF 384 dry ice Store all at -20ºC until use ¥8,500.00
Mediomics IHTR1010-100 hInsulin TRF 100 dry ice Store all at -20ºC until use ¥2,975.00
Mediomics IHTR1017-50 hInsulin TRF 50 dry ice Store all at -20ºC until use ¥3,740.00
Mediomics IHTR1017-96 hInsulin TRF 96 dry ice Store all at -20ºC until use ¥6,800.00
Mediomics MIGTR1012-384 mIgG TRF 384 dry ice Store all at -20ºC until use ¥8,500.00
Mediomics MIGTR1012-200 mIgG TRF 200 dry ice Store all at -20ºC until use ¥4,760.00
Mediomics CH1008-384 hCRP FRET 384 dry ice Store all at -20ºC until use ¥7,650.00
Mediomics CH1008-100 hCRP FRET 100 dry ice Store all at -20ºC until use ¥2,550.00
Mediomics AH1016-96 hAlbumin FRET 96 dry ice Store all at -20ºC until use ¥6,375.00
Mediomics AH1016-50 hAlbumin FRET 50 dry ice Store all at -20ºC until use ¥3,400.00
Mediomics AH1005-100 hAlbumin FRET 100 dry ice Store all at -20ºC until use ¥2,550.00
Mediomics AH1005-384 hAlbumin FRET 384 dry ice Store all at -20ºC until use ¥7,650.00
Mediomics TRF-1-1-1006B TR-FRET Bridge-It® L-MET 384 dry ice Store all at -20ºC until use ¥8,925.00
Mediomics TRF-1-1-1005B TR-FRET Bridge-It® L-MET 96 dry ice Store all at -20ºC until use ¥6,800.00
Mediomics TRF-1-1-1006A TR-FRET Bridge-It® L-MET 100 dry ice Store all at -20ºC until use ¥2,975.00
Mediomics TRF-1-1-1005A TR-FRET Bridge-It® L-MET 50 dry ice Store all at -20ºC until use ¥3,740.00
Mediomics TRF-1-1-1003B TR-FRET Bridge-It® SAM 96 dry ice Store all at -20ºC until use ¥6,800.00
Mediomics TRF-1-1-1003A TR-FRET Bridge-It® SAM 50 dry ice Store all at -20ºC until use ¥3,740.00
Mediomics TRF-1-1-1004B TR-FRET Bridge-It® SAM 384 dry ice Store all at -20ºC until use ¥8,925.00
Mediomics TRF-1-1-1004A TR-FRET Bridge-It® SAM 100 dry ice Store all at -20ºC until use ¥2,975.00
Mediomics TRF-1-1-1001A TR-FRET Bridge-It® L-Tryptophan 50 dry ice Store all at -20ºC until use ¥3,740.00
Mediomics TRF-1-1-1001B TR-FRET Bridge-It® L-Tryptophan 96 dry ice Store all at -20ºC until use ¥6,800.00
Mediomics TRF-1-1-1002B TR-FRET Bridge-It® L-Tryptophan 384 dry ice Store all at -20ºC until use ¥8,925.00
Mediomics TRF-1-1-1002A TR-FRET Bridge-It® L-Tryptophan 100 dry ice Store all at -20ºC until use ¥2,975.00
Mediomics 1-1-1001A Bridge-It L-Tryptophan 50 dry ice Store all at -20ºC until use ¥3,400.00
Mediomics 1-1-1001B Bridge-It L-Tryptophan 96 dry ice Store all at -20ºC until use ¥6,375.00
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