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LKT Labs Q8134Quinapril Hydrochloride

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LKT Labs 是一家专注于防癌抗癌特殊化学品研究和开发的公司。主要提供:癌症药物、药物发现试剂盒、天然产物、广泛的生命科学研究试剂、定制合成。
美国LKT Labs 是1988年在美国成立的,为全球提供先端的药物研发试剂、试剂盒、委托合成,并为药物生产企业提供原料,最近几年在农药、水产养殖业有很大程度的开发。LKT Labs Q8134Quinapril Hydrochloride

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LKT Labs 是一家专注于防癌抗癌特殊化学品研究和开发的公司。主要提供:癌症药物、药物发现试剂盒、天然产物、广泛的生命科学研究试剂、定制合成。
美国LKT Labs 是1988年在美国成立的,为全球提供先端的药物研发试剂、试剂盒、委托合成,并为药物生产企业提供原料,最近几年在农药、水产养殖业有很大程度的开发。在LKT Labs 可以找到在其他地方找不到的产品。

LKT Labs Q8134 Quinapril Hydrochloride

LKT Labs Q8134 Quinapril Hydrochloride

 

LKT D3447 Diltiazem Hydrochloride 10 g 380.5 Benzothiazepine; L-type Ca2+ channel blocker, potential CNG channel blocker. [(2S,3S)-5-(2-dimethylaminoethyl)-2-(4-methoxyphenyl)-4-oxo-2,3-dihydro-1,5-benzothiazepin-3-yl] acetate 33286-22-5 ≥98% 450.98 C22H26N2O4S HCl CC(=O)OC1C(SC2=CC=CC=C2N(C1=O)CCN(C)C)C3=CC=C(C=C3)OC.Cl Ambient Ambient "Mieth A, Revermann M, Babelova A, et al. L-type calcium channel inhibitor diltiazem prevents aneurysm formation by blood pressure-independent anti-inflammatory effects. Hypertension. 2013 Dec;62(6):1098-104. PMID: 24082061.

 

Matsushita S, Kurihara H, Watanabe M, et al. Inhibition of connexin43 dephosphorylation is involved in protective effects of diltiazem on cardiac function during hypoxic injury. Histol Histopathol. 2011 Mar;26(3):315-22. PMID: 21210344.

 

Podda MV, D'Ascenzo M, Leone L, et al. Functional role of cyclic nucleotide-gated channels in rat medial vestibular nucleus neurons. J Physiol. 2008 Feb 1;586(3):803-15. PMID: 18048449.

 

Joyal M, Cremer K, Pieper J, et al. Effects of diltiazem during tachycardia-induced angina pectoris. Am J Cardiol. 1986 Jan 1;57(1):10-4. PMID: 3942050.

" Not dangerous goods.

LKT D3462 Diphenhydramine Hydrochloride 10 g 32.3 Voltage-gated Na+ channel blocker, mAChR antagonist, histamine H1 inverse agonist. 2-Diphenylmethoxy-N,N-dimthylethanamine hydrochloride Alledryl; Amidryl; Benadryl; Dihydral; Dolestan; Halbmond; Noctomin; Syntedril 147-24-0 ≥98% 291.82 C17H21NO HCl CN(C)CCOC(C1=CC=CC=C1)C2=CC=CC=C2.Cl Ambient Ambient Soluble in acetone (20 mg/mL), water (1 g/mL), and alcohol (500 mg/mL). Slightly soluble in benzene or ether. "Raphael GD, Angello JT, Wu MM, et al. Efficacy of diphenhydramine vs desloratadine and placebo in patients with moderate-to-severe seasonal allergic rhinitis. Ann Allergy Asthma Immunol. 2006 Apr;96(4):606-14. PMID: 16680933.

 

Yamashiro K, Kiryu J, Tsujikawa A, et al. Suppressive effects of histamine H1 receptor antagonist diphenhydramine on the leukocyte infiltration during endotoxin-induced uveitis. Exp Eye Res. 2001 Jul;73(1):69-80. PMID: 11428864.

 

Kim YS, Shin YK, Lee C, et al. Block of sodium currents in rat dorsal root ganglion neurons by diphenhydramine. Brain Res. 2000 Oct 27;881(2):190-8. PMID: 11036158.

 

Reiner PB, Kamondi A. Mechanisms of antihistamine-induced sedation in the human brain: H1 receptor activation reduces a background leakage potassium current. Neuroscience. 1994 Apr;59(3):579-88. PMID: 8008209.

" Xn Not Dangerous Goods

LKT D3462 Diphenhydramine Hydrochloride 25 g 518 Voltage-gated Na+ channel blocker, mAChR antagonist, histamine H1 inverse agonist. 2-Diphenylmethoxy-N,N-dimthylethanamine hydrochloride Alledryl; Amidryl; Benadryl; Dihydral; Dolestan; Halbmond; Noctomin; Syntedril 147-24-0 ≥98% 291.82 C17H21NO HCl CN(C)CCOC(C1=CC=CC=C1)C2=CC=CC=C2.Cl Ambient Ambient Soluble in acetone (20 mg/mL), water (1 g/mL), and alcohol (500 mg/mL). Slightly soluble in benzene or ether. "Raphael GD, Angello JT, Wu MM, et al. Efficacy of diphenhydramine vs desloratadine and placebo in patients with moderate-to-severe seasonal allergic rhinitis. Ann Allergy Asthma Immunol. 2006 Apr;96(4):606-14. PMID: 16680933.

 

Yamashiro K, Kiryu J, Tsujikawa A, et al. Suppressive effects of histamine H1 receptor antagonist diphenhydramine on the leukocyte infiltration during endotoxin-induced uveitis. Exp Eye Res. 2001 Jul;73(1):69-80. PMID: 11428864.

 

Kim YS, Shin YK, Lee C, et al. Block of sodium currents in rat dorsal root ganglion neurons by diphenhydramine. Brain Res. 2000 Oct 27;881(2):190-8. PMID: 11036158.

 

Reiner PB, Kamondi A. Mechanisms of antihistamine-induced sedation in the human brain: H1 receptor activation reduces a background leakage potassium current. Neuroscience. 1994 Apr;59(3):579-88. PMID: 8008209.

" Xn Not Dangerous Goods

LKT D3462 Diphenhydramine Hydrochloride 100 g 77.7 Voltage-gated Na+ channel blocker, mAChR antagonist, histamine H1 inverse agonist. 2-Diphenylmethoxy-N,N-dimthylethanamine hydrochloride Alledryl; Amidryl; Benadryl; Dihydral; Dolestan; Halbmond; Noctomin; Syntedril 147-24-0 ≥98% 291.82 C17H21NO HCl CN(C)CCOC(C1=CC=CC=C1)C2=CC=CC=C2.Cl Ambient Ambient Soluble in acetone (20 mg/mL), water (1 g/mL), and alcohol (500 mg/mL). Slightly soluble in benzene or ether. "Raphael GD, Angello JT, Wu MM, et al. Efficacy of diphenhydramine vs desloratadine and placebo in patients with moderate-to-severe seasonal allergic rhinitis. Ann Allergy Asthma Immunol. 2006 Apr;96(4):606-14. PMID: 16680933.

 

Yamashiro K, Kiryu J, Tsujikawa A, et al. Suppressive effects of histamine H1 receptor antagonist diphenhydramine on the leukocyte infiltration during endotoxin-induced uveitis. Exp Eye Res. 2001 Jul;73(1):69-80. PMID: 11428864.

 

Kim YS, Shin YK, Lee C, et al. Block of sodium currents in rat dorsal root ganglion neurons by diphenhydramine. Brain Res. 2000 Oct 27;881(2):190-8. PMID: 11036158.

 

Reiner PB, Kamondi A. Mechanisms of antihistamine-induced sedation in the human brain: H1 receptor activation reduces a background leakage potassium current. Neuroscience. 1994 Apr;59(3):579-88. PMID: 8008209.

" Xn Not Dangerous Goods

LKT D4802 17-Dimethylaminoethylamino Demethoxygeldanamycin 1 mg 48.5 Geldanamycin derivative; HSP90 inhibitor. 17-DMAG, Alvespimycin 467214-20-6 ≥98% 616.75 C32H48N4O8 CC1CCCC(CCC(=O)OC23C(C=CC1)C(C(=C)C(C2C(NC3=O)CC4=CC=CC=C4)C)O)O Ambient 4°C DMSO, Ethanol "Silva-Fernandes A, Duarte-Silva S, Neves-Carvalho A, et al. Chronic Treatment with 17-DMAG Improves Balance and Coordination in A New Mouse Model of Machado-Joseph Disease. Neurotherapeutics. 2014 Jan 30. [Epub ahead of print]. PMID: 24477711.

 

Yi B, Yang J, Wang L. The growth inhibitory effect of 17-DMAG on ALK and MYCN double-positive neuroblastoma cell line. Tumour Biol. 2013 Nov 30. [Epub ahead of print]. PMID: 24293393.

 

Sun X, Bristol JA, Iwahori S, et al. Hsp90 inhibitor 17-DMAG decreases expression of conserved herpesvirus protein kinases and reduces virus production in Epstein-Barr virus-infected cells. J Virol. 2013 Sep;87(18):10126-38. PMID: 23843639.

 

Ikebe E, Kawaguchi A, Tezuka K, et al. Oral administration of an HSP90 inhibitor, 17-DMAG, intervenes tumor-cell infiltration into multiple organs and improves survival period for ATL model mice. Blood Cancer J. 2013 Aug 16;3:e132. PMID: 23955587.

" Not dangerous goods.

LKT D4802 17-Dimethylaminoethylamino Demethoxygeldanamycin 5 mg 97 Geldanamycin derivative; HSP90 inhibitor. 17-DMAG, Alvespimycin 467214-20-6 ≥98% 616.75 C32H48N4O8 CC1CCCC(CCC(=O)OC23C(C=CC1)C(C(=C)C(C2C(NC3=O)CC4=CC=CC=C4)C)O)O Ambient 4°C DMSO, Ethanol "Silva-Fernandes A, Duarte-Silva S, Neves-Carvalho A, et al. Chronic Treatment with 17-DMAG Improves Balance and Coordination in A New Mouse Model of Machado-Joseph Disease. Neurotherapeutics. 2014 Jan 30. [Epub ahead of print]. PMID: 24477711.

 

Yi B, Yang J, Wang L. The growth inhibitory effect of 17-DMAG on ALK and MYCN double-positive neuroblastoma cell line. Tumour Biol. 2013 Nov 30. [Epub ahead of print]. PMID: 24293393.

 

Sun X, Bristol JA, Iwahori S, et al. Hsp90 inhibitor 17-DMAG decreases expression of conserved herpesvirus protein kinases and reduces virus production in Epstein-Barr virus-infected cells. J Virol. 2013 Sep;87(18):10126-38. PMID: 23843639.

 

Ikebe E, Kawaguchi A, Tezuka K, et al. Oral administration of an HSP90 inhibitor, 17-DMAG, intervenes tumor-cell infiltration into multiple organs and improves survival period for ATL model mice. Blood Cancer J. 2013 Aug 16;3:e132. PMID: 23955587.

" Not dangerous goods.

LKT D4873 Meso-2,3-dimercaptosuccinic Acid 1 g 33.9 Organosulfur, chelating agent. (2R, 3S)-rel-2,3-Dimer-captobutanedioic acid Succimer; DMS; DMSA 304-55-2 ≥98% 182.22 C4H6O4S2 C(C(C(=O)O)S)(C(=O)O)S Ambient Ambient Soluble in water. "Wright JW, Duguid R, McKiddie F, et al. Automatic classification of DMSA scans using an artificial neural network. Phys Med Biol. 2014 Apr 7;59(7):1789-800. PMID: 24619240.

 

Rooney JP. The role of thiols, dithiols, nutritional factors and interacting ligands in the toxicology of mercury. Toxicology. 2007 May 20;234(3):145-56. Erratum in: Toxicology. 2007 Sep 5;238(2-3):216. PMID: 17408840.

" None Not dangerous goods.

LKT D4873 Meso-2,3-dimercaptosuccinic Acid 5 g 97.8 Organosulfur, chelating agent. (2R, 3S)-rel-2,3-Dimer-captobutanedioic acid Succimer; DMS; DMSA 304-55-2 ≥98% 182.22 C4H6O4S2 C(C(C(=O)O)S)(C(=O)O)S Ambient Ambient Soluble in water. "Wright JW, Duguid R, McKiddie F, et al. Automatic classification of DMSA scans using an artificial neural network. Phys Med Biol. 2014 Apr 7;59(7):1789-800. PMID: 24619240.

 

Rooney JP. The role of thiols, dithiols, nutritional factors and interacting ligands in the toxicology of mercury. Toxicology. 2007 May 20;234(3):145-56. Erratum in: Toxicology. 2007 Sep 5;238(2-3):216. PMID: 17408840.

" None Not dangerous goods.

LKT D4873 Meso-2,3-dimercaptosuccinic Acid 25 g 339.8 Organosulfur, chelating agent. (2R, 3S)-rel-2,3-Dimer-captobutanedioic acid Succimer; DMS; DMSA 304-55-2 ≥98% 182.22 C4H6O4S2 C(C(C(=O)O)S)(C(=O)O)S Ambient Ambient Soluble in water. "Wright JW, Duguid R, McKiddie F, et al. Automatic classification of DMSA scans using an artificial neural network. Phys Med Biol. 2014 Apr 7;59(7):1789-800. PMID: 24619240.

 

Rooney JP. The role of thiols, dithiols, nutritional factors and interacting ligands in the toxicology of mercury. Toxicology. 2007 May 20;234(3):145-56. Erratum in: Toxicology. 2007 Sep 5;238(2-3):216. PMID: 17408840.

" None Not dangerous goods.

LKT D5607 Dobutamine Hydrochloride 10 mg 67.9 β1-adrenergic agonist, β2- and α1-adrenergic  antagonist. 4-[2-[[3-(4-Hydroxyphenyl)1-methylpropyl]amino]- ethyl]-1,2-benzenediol hydrochloride "Dobutrex

 

" 49745-95-1 ≥98% 337.85 C18H23NO3 HCl CC(CCC1=CC=C(C=C1)O)NCCC2=CC(=C(C=C2)O)O.Cl Hygroscopic. Ambient Ambient Soluble in water, alcohol and pyridine. "Bateman RJ, Boychuk CR, Philbin KE, et al. β adrenergic receptor modulation of neurotransmission to cardiac vagal neurons in the nucleus ambiguus. Neuroscience. 2012 May 17;210:58-66. PMID: 22425752.

 

Coons JC, McGraw M, Murali S. Pharmacotherapy for acute heart failure syndromes. Am J Health Syst Pharm. 2011 Jan 1;68(1):21-35. PMID: 21164062.

 

Previtali M, Camporotondo R, Repetto A, et al. Dobutamine stress echocardiography for assessing the role of dynamic intraventricular obstruction in left ventricular ballooning syndrome. Cardiovasc Ultrasound. 2010 Apr 9;8:11. PMID: 20380731.

" Xn Not dangerous goods.

LKT D5607 Dobutamine Hydrochloride 50 mg 224.5 β1-adrenergic agonist, β2- and α1-adrenergic  antagonist. 4-[2-[[3-(4-Hydroxyphenyl)1-methylpropyl]amino]- ethyl]-1,2-benzenediol hydrochloride "Dobutrex

 

" 49745-95-1 ≥98% 337.85 C18H23NO3 HCl CC(CCC1=CC=C(C=C1)O)NCCC2=CC(=C(C=C2)O)O.Cl Hygroscopic. Ambient Ambient Soluble in water, alcohol and pyridine. "Bateman RJ, Boychuk CR, Philbin KE, et al. β adrenergic receptor modulation of neurotransmission to cardiac vagal neurons in the nucleus ambiguus. Neuroscience. 2012 May 17;210:58-66. PMID: 22425752.

 

Coons JC, McGraw M, Murali S. Pharmacotherapy for acute heart failure syndromes. Am J Health Syst Pharm. 2011 Jan 1;68(1):21-35. PMID: 21164062.

 

Previtali M, Camporotondo R, Repetto A, et al. Dobutamine stress echocardiography for assessing the role of dynamic intraventricular obstruction in left ventricular ballooning syndrome. Cardiovasc Ultrasound. 2010 Apr 9;8:11. PMID: 20380731.

" Xn Not dangerous goods.

LKT D5607 Dobutamine Hydrochloride 100 mg 370.1 β1-adrenergic agonist, β2- and α1-adrenergic  antagonist. 4-[2-[[3-(4-Hydroxyphenyl)1-methylpropyl]amino]- ethyl]-1,2-benzenediol hydrochloride "Dobutrex

 

" 49745-95-1 ≥98% 337.85 C18H23NO3 HCl CC(CCC1=CC=C(C=C1)O)NCCC2=CC(=C(C=C2)O)O.Cl Hygroscopic. Ambient Ambient Soluble in water, alcohol and pyridine. "Bateman RJ, Boychuk CR, Philbin KE, et al. β adrenergic receptor modulation of neurotransmission to cardiac vagal neurons in the nucleus ambiguus. Neuroscience. 2012 May 17;210:58-66. PMID: 22425752.

 

Coons JC, McGraw M, Murali S. Pharmacotherapy for acute heart failure syndromes. Am J Health Syst Pharm. 2011 Jan 1;68(1):21-35. PMID: 21164062.

 

Previtali M, Camporotondo R, Repetto A, et al. Dobutamine stress echocardiography for assessing the role of dynamic intraventricular obstruction in left ventricular ballooning syndrome. Cardiovasc Ultrasound. 2010 Apr 9;8:11. PMID: 20380731.

" Xn Not dangerous goods.

LKT D5649 Domperidone 50 mg 60.3 D2/3 antagonist, hERG K+ channel blocker. 5-Chloro-1-[1-[3-(2,3-dihydro-2-oxo-1H- benzimidazol-1-yl)propyl]-4-piperidinyl]-1,3-dihydro- 2H-benzimidazol-2-one Euciton; Evoxin; Mod; Motilium; Nnauzelin: Peridon; Peridys 57808-66-9 ≥98% 425.91 C22H24</sub>ClN5O2 C1CN(CCC1N2C3=C(C=C(C=C3)Cl)NC2=O)CCCN4C5=CC=CC=C5NC4=O Ambient Ambient Slightly soluble in water (0.986 mg/L).  soluble in dimethylformamide, slightly soluble in alcohol and in  methanol "Claassen S, Zünkler BJ. Comparison of the effects of metoclopramide and domperidone on HERG channels. Pharmacology. 2005 Apr;74(1):31-6. PMID: 15640612.

 

Sivasanker M, Reddy PM, Shashindran CH, et al. Formalin assay parameters differ in confirming the antinociceptive mechanism of domperidone in mice. Indian J Exp Biol. 2004 Apr;42(4):429-31. PMID: 15088695.

" Xn Not dangerous goods.

LKT D5649 Domperidone 250 mg 231.1 D2/3 antagonist, hERG K+ channel blocker. 5-Chloro-1-[1-[3-(2,3-dihydro-2-oxo-1H- benzimidazol-1-yl)propyl]-4-piperidinyl]-1,3-dihydro- 2H-benzimidazol-2-one Euciton; Evoxin; Mod; Motilium; Nnauzelin: Peridon; Peridys 57808-66-9 ≥98% 425.91 C22H24</sub>ClN5O2 C1CN(CCC1N2C3=C(C=C(C=C3)Cl)NC2=O)CCCN4C5=CC=CC=C5NC4=O Ambient Ambient Slightly soluble in water (0.986 mg/L).  soluble in dimethylformamide, slightly soluble in alcohol and in  methanol "Claassen S, Zünkler BJ. Comparison of the effects of metoclopramide and domperidone on HERG channels. Pharmacology. 2005 Apr;74(1):31-6. PMID: 15640612.

 

Sivasanker M, Reddy PM, Shashindran CH, et al. Formalin assay parameters differ in confirming the antinociceptive mechanism of domperidone in mice. Indian J Exp Biol. 2004 Apr;42(4):429-31. PMID: 15088695.

" Xn Not dangerous goods.

LKT D5649 Domperidone 1 g 739.5 D2/3 antagonist, hERG K+ channel blocker. 5-Chloro-1-[1-[3-(2,3-dihydro-2-oxo-1H- benzimidazol-1-yl)propyl]-4-piperidinyl]-1,3-dihydro- 2H-benzimidazol-2-one Euciton; Evoxin; Mod; Motilium; Nnauzelin: Peridon; Peridys 57808-66-9 ≥98% 425.91 C22H24</sub>ClN5O2 C1CN(CCC1N2C3=C(C=C(C=C3)Cl)NC2=O)CCCN4C5=CC=CC=C5NC4=O Ambient Ambient Slightly soluble in water (0.986 mg/L).  soluble in dimethylformamide, slightly soluble in alcohol and in  methanol "Claassen S, Zünkler BJ. Comparison of the effects of metoclopramide and domperidone on HERG channels. Pharmacology. 2005 Apr;74(1):31-6. PMID: 15640612.

 

Sivasanker M, Reddy PM, Shashindran CH, et al. Formalin assay parameters differ in confirming the antinociceptive mechanism of domperidone in mice. Indian J Exp Biol. 2004 Apr;42(4):429-31. PMID: 15088695.

" Xn Not dangerous goods.

LKT D5662 Dopamine Hydrochloride 5 g 33.9 Endogenous hormone neurotransmitter, involved in motor control, mood, cognition, reward, and nausea; D1-5 agonist. 4-(2-Aminoethyl)-1,2-benzenediol hydrochloride Cariosteril; Dopastat; Dynatra; Inovan; Inotropin 62-31-7 ≥98% 189.64 C8H11NO2 HCl C1=CC(=C(C=C1CCN)O)O.Cl Ambient Ambient Soluble in water (100 mM), methanol and hot ethanol (20 mg/mL). DMSO to 38 mg/mL. Practically insoluble in ether, chloroform, benzene and toluene. "Cachope R, Cheer JF. Local control of striatal dopamine release. Front Behav Neurosci. 2014 May 23;8:188. PMID: 24904339.

 

Pacheco R, Contreras F, Zouali M. The dopaminergic system in autoimmune diseases. Front Immunol. 2014 Mar 21;5:117. PMID: 24711809.

 

Blier P. Neurotransmitter targeting in the treatment of depression. J Clin Psychiatry. 2013;74 Suppl 2:19-24. PMID: 24191974.

 

Sarkar C, Basu B, Chakroborty D, et al. The immunoregulatory role of dopamine: an update. Brain Behav Immun. 2010 May;24(4):525-8. dPMID: 19896530.

" Xn, N "UN number: 3077     Class: 9     Packing group: III

Proper shipping name: Environmentally hazardous substances, solid, n.o.s. (Dopamine hydrochloride)

Marine pollutant:yes Poison Inhalation Hazard: No"

LKT D5662 Dopamine Hydrochloride 25 g 88.3 Endogenous hormone neurotransmitter, involved in motor control, mood, cognition, reward, and nausea; D1-5 agonist. 4-(2-Aminoethyl)-1,2-benzenediol hydrochloride Cariosteril; Dopastat; Dynatra; Inovan; Inotropin 62-31-7 ≥98% 189.64 C8H11NO2 HCl C1=CC(=C(C=C1CCN)O)O.Cl Ambient Ambient Soluble in water (100 mM), methanol and hot ethanol (20 mg/mL). DMSO to 38 mg/mL. Practically insoluble in ether, chloroform, benzene and toluene. "Cachope R, Cheer JF. Local control of striatal dopamine release. Front Behav Neurosci. 2014 May 23;8:188. PMID: 24904339.

 

Pacheco R, Contreras F, Zouali M. The dopaminergic system in autoimmune diseases. Front Immunol. 2014 Mar 21;5:117. PMID: 24711809.

 

Blier P. Neurotransmitter targeting in the treatment of depression. J Clin Psychiatry. 2013;74 Suppl 2:19-24. PMID: 24191974.

 

Sarkar C, Basu B, Chakroborty D, et al. The immunoregulatory role of dopamine: an update. Brain Behav Immun. 2010 May;24(4):525-8. dPMID: 19896530.

" Xn, N "UN number: 3077     Class: 9     Packing group: III

Proper shipping name: Environmentally hazardous substances, solid, n.o.s. (Dopamine hydrochloride)

Marine pollutant:yes Poison Inhalation Hazard: No"

LKT D5662 Dopamine Hydrochloride 100 g 305.9 Endogenous hormone neurotransmitter, involved in motor control, mood, cognition, reward, and nausea; D1-5 agonist. 4-(2-Aminoethyl)-1,2-benzenediol hydrochloride Cariosteril; Dopastat; Dynatra; Inovan; Inotropin 62-31-7 ≥98% 189.64 C8H11NO2 HCl C1=CC(=C(C=C1CCN)O)O.Cl Ambient Ambient Soluble in water (100 mM), methanol and hot ethanol (20 mg/mL). DMSO to 38 mg/mL. Practically insoluble in ether, chloroform, benzene and toluene. "Cachope R, Cheer JF. Local control of striatal dopamine release. Front Behav Neurosci. 2014 May 23;8:188. PMID: 24904339.

 

Pacheco R, Contreras F, Zouali M. The dopaminergic system in autoimmune diseases. Front Immunol. 2014 Mar 21;5:117. PMID: 24711809.

 

Blier P. Neurotransmitter targeting in the treatment of depression. J Clin Psychiatry. 2013;74 Suppl 2:19-24. PMID: 24191974.

 

Sarkar C, Basu B, Chakroborty D, et al. The immunoregulatory role of dopamine: an update. Brain Behav Immun. 2010 May;24(4):525-8. dPMID: 19896530.

" Xn, N "UN number: 3077     Class: 9     Packing group: III

Proper shipping name: Environmentally hazardous substances, solid, n.o.s. (Dopamine hydrochloride)

Marine pollutant:yes Poison Inhalation Hazard: No"

LKT D5690 Doxazosin Mesylate 50 mg 67.9 Quinazoline; α1-adrenergic antagonist. 1-(4-Amino-6,7-dimethoxy-2-quinazolinyl)-4-[(2,3- dihydro-1,4-benzodioxan-2-yl)carbonyl)piperazine methanesulfonate Doxazosin Methanesulfonate; Alfadil; Benur; Cardular; Carduran; Normothen; Supressin; Zoxan 77883-43-3 ≥98% 547.59 C23H25N5O5 CH3SO3H COC1=C(C=C2C(=C1)C(=NC(=N2)N3CCN(CC3)C(=O)C4COC5=CC=CC=C5O4)N)OC.CS(=O)(=O)O Ambient Ambient Slightly soluble in water. "Shannon R, Chaudhry M. Effect of alpha1-adrenergic receptors in cardiac pathophysiology. Am Heart J. 2006 Nov;152(5):842-50. PMID: 17070143.

 

Garrison JB, Kyprianou N. Doxazosin induces apoptosis of benign and malignant prostate cells via a death receptor-mediated pathway. Cancer Res. 2006 Jan 1;66(1):464-72. PMID: 16397262.

 

Kyprianou N. Doxazosin and terazosin suppress prostate growth by inducing apoptosis: clinical significance. J Urol. 2003 Apr;169(4):1520-5. PMID: 12629407.

" None Not dangerous goods.

LKT D5690 Doxazosin Mesylate 250 mg 367 Quinazoline; α1-adrenergic antagonist. 1-(4-Amino-6,7-dimethoxy-2-quinazolinyl)-4-[(2,3- dihydro-1,4-benzodioxan-2-yl)carbonyl)piperazine methanesulfonate Doxazosin Methanesulfonate; Alfadil; Benur; Cardular; Carduran; Normothen; Supressin; Zoxan 77883-43-3 ≥98% 547.59 C23H25N5O5 CH3SO3H COC1=C(C=C2C(=C1)C(=NC(=N2)N3CCN(CC3)C(=O)C4COC5=CC=CC=C5O4)N)OC.CS(=O)(=O)O Ambient Ambient Slightly soluble in water. "Shannon R, Chaudhry M. Effect of alpha1-adrenergic receptors in cardiac pathophysiology. Am Heart J. 2006 Nov;152(5):842-50. PMID: 17070143.

 

Garrison JB, Kyprianou N. Doxazosin induces apoptosis of benign and malignant prostate cells via a death receptor-mediated pathway. Cancer Res. 2006 Jan 1;66(1):464-72. PMID: 16397262.

 

Kyprianou N. Doxazosin and terazosin suppress prostate growth by inducing apoptosis: clinical significance. J Urol. 2003 Apr;169(4):1520-5. PMID: 12629407.

" None Not dangerous goods.

LKT D5690 Doxazosin Mesylate 1 g 815.4 Quinazoline; α1-adrenergic antagonist. 1-(4-Amino-6,7-dimethoxy-2-quinazolinyl)-4-[(2,3- dihydro-1,4-benzodioxan-2-yl)carbonyl)piperazine methanesulfonate Doxazosin Methanesulfonate; Alfadil; Benur; Cardular; Carduran; Normothen; Supressin; Zoxan 77883-43-3 ≥98% 547.59 C23H25N5O5 CH3SO3H COC1=C(C=C2C(=C1)C(=NC(=N2)N3CCN(CC3)C(=O)C4COC5=CC=CC=C5O4)N)OC.CS(=O)(=O)O Ambient Ambient Slightly soluble in water. "Shannon R, Chaudhry M. Effect of alpha1-adrenergic receptors in cardiac pathophysiology. Am Heart J. 2006 Nov;152(5):842-50. PMID: 17070143.

 

Garrison JB, Kyprianou N. Doxazosin induces apoptosis of benign and malignant prostate cells via a death receptor-mediated pathway. Cancer Res. 2006 Jan 1;66(1):464-72. PMID: 16397262.

 

Kyprianou N. Doxazosin and terazosin suppress prostate growth by inducing apoptosis: clinical significance. J Urol. 2003 Apr;169(4):1520-5. PMID: 12629407.

" None Not dangerous goods.

LKT D5692 Doxifluridine 50 mg 73.4 5-Fluorouracil prodrug, pyrimidine nucleoside analog; thymidylate synthase inhibitor. 5'-Deoxy-5-fluorouridine 5'-DFUR; Flutron; Furtulon 3094-09-5 ≥98% 246.19 C9H11FN2O5 CC1C(C(C(O1)N2C=C(C(=O)NC2=O)F)O)O Hygroscopic. Ambient Ambient "Zhao WH, Wang SF, Ding W, et al. Apoptosis induced by preoperative oral 5'-DFUR administration in gastric adenocarcinoma and its mechanism of action. World J Gastroenterol. 2006 Mar 7;12(9):1356-61. PMID: 16552801.

 

Saurat JH. Retinoids and psoriasis: novel issues in retinoid pharmacology and implications for psoriasis treatment. J Am Acad Dermatol. 1999 Sep;41(3 Pt 2):S2-6. PMID: 10459139.

" None Not dangerous goods.

LKT D5692 Doxifluridine 100 mg 130.4 5-Fluorouracil prodrug, pyrimidine nucleoside analog; thymidylate synthase inhibitor. 5'-Deoxy-5-fluorouridine 5'-DFUR; Flutron; Furtulon 3094-09-5 ≥98% 246.19 C9H11FN2O5 CC1C(C(C(O1)N2C=C(C(=O)NC2=O)F)O)O Hygroscopic. Ambient Ambient "Zhao WH, Wang SF, Ding W, et al. Apoptosis induced by preoperative oral 5'-DFUR administration in gastric adenocarcinoma and its mechanism of action. World J Gastroenterol. 2006 Mar 7;12(9):1356-61. PMID: 16552801.

 

Saurat JH. Retinoids and psoriasis: novel issues in retinoid pharmacology and implications for psoriasis treatment. J Am Acad Dermatol. 1999 Sep;41(3 Pt 2):S2-6. PMID: 10459139.

" None Not dangerous goods.

LKT D5709 Docetaxel 5 mg 95.1 Semi-synthetic analog of taxol; microtubule depolymerization inhibitor. (αR,βS)-β-[[(1,1-Dimethylethoxy)carbonyl]amino]-α-hydroxybenzenepropanoic acid (2aR,4S,4aS,6R,9S,- 11S,12S,12aR,12bS)-12b-(acetyloxy)-12(benzoyloxy)- 2a,3,4,4a,5,6,9,10,11,12,12a,12b-dodecahydro-4,6,11- trihydroxy-4a,8,13,13-tetramethyl-5-oxo-7,11-methano-1H-cyclodeca[3,4]benz[1,2-b]oxet-9-yl ester N-debenzoyl-N-(tert-butoxycarbonyl)-10-deacetyltaxol; Taxotere 114977-28-5 ≥98% 807.89 C43H53NO14 CC1=C2C(C(=O)C3(C(CC4C(C3C(C(C2(C)C)(CC1OC(=O)C(C(C5=CC=CC=C5)NC(=O)OC(C)(C)C)O)O)OC(=O)C6=CC=CC=C6)(CO4)OC(=O)C)O)C)O In DMSO at +4 for 2 weeks at -80 for 6 months. Ambient -20°C Soluble in DMSO, ethanol, chloroform, dichloromethane, ethyl acetate, methanol. Insoluble in water. "Lyseng-Williamson KA, Fenton C. Docetaxel: a review of its use in metastatic breast cancer. Drugs. 2005;65(17):2513-31. PMID: 16296875.

 

Eisenhauer EA, Vermorken JB. The taxoids. Comparative clinical pharmacology and therapeutic potential. Drugs. 1998 Jan;55(1):5-30. PMID: 9463787.

" None Not dangerous goods.

LKT D5709 Docetaxel 10 mg 163.2 Semi-synthetic analog of taxol; microtubule depolymerization inhibitor. (αR,βS)-β-[[(1,1-Dimethylethoxy)carbonyl]amino]-α-hydroxybenzenepropanoic acid (2aR,4S,4aS,6R,9S,- 11S,12S,12aR,12bS)-12b-(acetyloxy)-12(benzoyloxy)- 2a,3,4,4a,5,6,9,10,11,12,12a,12b-dodecahydro-4,6,11- trihydroxy-4a,8,13,13-tetramethyl-5-oxo-7,11-methano-1H-cyclodeca[3,4]benz[1,2-b]oxet-9-yl ester N-debenzoyl-N-(tert-butoxycarbonyl)-10-deacetyltaxol; Taxotere 114977-28-5 ≥98% 807.89 C43H53NO14 CC1=C2C(C(=O)C3(C(CC4C(C3C(C(C2(C)C)(CC1OC(=O)C(C(C5=CC=CC=C5)NC(=O)OC(C)(C)C)O)O)OC(=O)C6=CC=CC=C6)(CO4)OC(=O)C)O)C)O In DMSO at +4 for 2 weeks at -80 for 6 months. Ambient -20°C Soluble in DMSO, ethanol, chloroform, dichloromethane, ethyl acetate, methanol. Insoluble in water. "Lyseng-Williamson KA, Fenton C. Docetaxel: a review of its use in metastatic breast cancer. Drugs. 2005;65(17):2513-31. PMID: 16296875.

 

Eisenhauer EA, Vermorken JB. The taxoids. Comparative clinical pharmacology and therapeutic potential. Drugs. 1998 Jan;55(1):5-30. PMID: 9463787.

" None Not dangerous goods.

LKT D5709 Docetaxel 25 mg 394.2 Semi-synthetic analog of taxol; microtubule depolymerization inhibitor. (αR,βS)-β-[[(1,1-Dimethylethoxy)carbonyl]amino]-α-hydroxybenzenepropanoic acid (2aR,4S,4aS,6R,9S,- 11S,12S,12aR,12bS)-12b-(acetyloxy)-12(benzoyloxy)- 2a,3,4,4a,5,6,9,10,11,12,12a,12b-dodecahydro-4,6,11- trihydroxy-4a,8,13,13-tetramethyl-5-oxo-7,11-methano-1H-cyclodeca[3,4]benz[1,2-b]oxet-9-yl ester N-debenzoyl-N-(tert-butoxycarbonyl)-10-deacetyltaxol; Taxotere 114977-28-5 ≥98% 807.89 C43H53NO14 CC1=C2C(C(=O)C3(C(CC4C(C3C(C(C2(C)C)(CC1OC(=O)C(C(C5=CC=CC=C5)NC(=O)OC(C)(C)C)O)O)OC(=O)C6=CC=CC=C6)(CO4)OC(=O)C)O)C)O In DMSO at +4 for 2 weeks at -80 for 6 months. Ambient -20°C Soluble in DMSO, ethanol, chloroform, dichloromethane, ethyl acetate, methanol. Insoluble in water. "Lyseng-Williamson KA, Fenton C. Docetaxel: a review of its use in metastatic breast cancer. Drugs. 2005;65(17):2513-31. PMID: 16296875.

 

Eisenhauer EA, Vermorken JB. The taxoids. Comparative clinical pharmacology and therapeutic potential. Drugs. 1998 Jan;55(1):5-30. PMID: 9463787.

" None Not dangerous goods.

LKT D5746 Dolasetron 5 mg 127.5 5-HT3 antagonist. 115956-12-2 ≥98% 324.37 C19H20N2O3 C1C2CC3CC(CC1N3CC2=O)OC(=O)C4=CNC5=CC=CC=C54 Ambient Ambient Soluble in water and ethanol. "Hsu ES. A review of granisetron, 5-hydroxytryptamine3 receptor antagonists, and other antiemetics. Am J Ther. 2010 Sep-Oct;17(5):476-86. PMID: 20844345.

 

Birmingham SD, Mecklenburg BW, Lujan E, et al. Dolasetron versus ondansetron as single-agent prophylaxis for patients at increased risk for postoperative nausea and vomiting: a prospective, double-blind, randomized trial. Mil Med. 2006 Sep;171(9):913-6. PMID: 17036618.

" Not dangerous goods.

LKT D5746 Dolasetron 25 mg 515.7 5-HT3 antagonist. 115956-12-2 ≥98% 324.37 C19H20N2O3 C1C2CC3CC(CC1N3CC2=O)OC(=O)C4=CNC5=CC=CC=C54 Ambient Ambient Soluble in water and ethanol. "Hsu ES. A review of granisetron, 5-hydroxytryptamine3 receptor antagonists, and other antiemetics. Am J Ther. 2010 Sep-Oct;17(5):476-86. PMID: 20844345.

 

Birmingham SD, Mecklenburg BW, Lujan E, et al. Dolasetron versus ondansetron as single-agent prophylaxis for patients at increased risk for postoperative nausea and vomiting: a prospective, double-blind, randomized trial. Mil Med. 2006 Sep;171(9):913-6. PMID: 17036618.

" Not dangerous goods.

LKT D5746 Dolasetron 100 mg 1406.4 5-HT3 antagonist. 115956-12-2 ≥98% 324.37 C19H20N2O3 C1C2CC3CC(CC1N3CC2=O)OC(=O)C4=CNC5=CC=CC=C54 Ambient Ambient Soluble in water and ethanol. "Hsu ES. A review of granisetron, 5-hydroxytryptamine3 receptor antagonists, and other antiemetics. Am J Ther. 2010 Sep-Oct;17(5):476-86. PMID: 20844345.

 

Birmingham SD, Mecklenburg BW, Lujan E, et al. Dolasetron versus ondansetron as single-agent prophylaxis for patients at increased risk for postoperative nausea and vomiting: a prospective, double-blind, randomized trial. Mil Med. 2006 Sep;171(9):913-6. PMID: 17036618.

" Not dangerous goods.

LKT D5792 Doxofylline 1 g 101.9 Xanthine derivative; PDE inhibitor. 7-(1,3-Dioxolan-2-yl-methyl)-3,7-dihydro-1,3- dimethyl-1H-purine-2,6-dione Ansimar; Maxivent; Ventax 69975-86-6 ≥98% 266.25 C11H14N4O4 CN1C2=C(C(=O)N(C1=O)C)N(C=N2)CC3OCCO3 Ambient Ambient Soluble in water, acetone, ethyl acetate, hot methanol, hot ethanol, benzene or chloroform. "Shukla D, Chakraborty S, Singh S, et al. Doxofylline: a promising methylxanthine derivative for the treatment of asthma and chronic obstructive pulmonary disease. Expert Opin Pharmacother. 2009 Oct;10(14):2343-56. PMID: 19678793.

 

Cirillo R, Barone D, Franzone JS. Doxofylline, an antiasthmatic drug lacking affinity for adenosine receptors. Arch Int Pharmacodyn Ther. 1988 Sep-Oct;295:221-37. PMID: 3245738.

" Not dangerous goods.

LKT D5792 Doxofylline 5 g 305.9 Xanthine derivative; PDE inhibitor. 7-(1,3-Dioxolan-2-yl-methyl)-3,7-dihydro-1,3- dimethyl-1H-purine-2,6-dione Ansimar; Maxivent; Ventax 69975-86-6 ≥98% 266.25 C11H14N4O4 CN1C2=C(C(=O)N(C1=O)C)N(C=N2)CC3OCCO3 Ambient Ambient Soluble in water, acetone, ethyl acetate, hot methanol, hot ethanol, benzene or chloroform. "Shukla D, Chakraborty S, Singh S, et al. Doxofylline: a promising methylxanthine derivative for the treatment of asthma and chronic obstructive pulmonary disease. Expert Opin Pharmacother. 2009 Oct;10(14):2343-56. PMID: 19678793.

 

Cirillo R, Barone D, Franzone JS. Doxofylline, an antiasthmatic drug lacking affinity for adenosine receptors. Arch Int Pharmacodyn Ther. 1988 Sep-Oct;295:221-37. PMID: 3245738.

" Not dangerous goods.

LKT D5792 Doxofylline 25 g 883.3 Xanthine derivative; PDE inhibitor. 7-(1,3-Dioxolan-2-yl-methyl)-3,7-dihydro-1,3- dimethyl-1H-purine-2,6-dione Ansimar; Maxivent; Ventax 69975-86-6 ≥98% 266.25 C11H14N4O4 CN1C2=C(C(=O)N(C1=O)C)N(C=N2)CC3OCCO3 Ambient Ambient Soluble in water, acetone, ethyl acetate, hot methanol, hot ethanol, benzene or chloroform. "Shukla D, Chakraborty S, Singh S, et al. Doxofylline: a promising methylxanthine derivative for the treatment of asthma and chronic obstructive pulmonary disease. Expert Opin Pharmacother. 2009 Oct;10(14):2343-56. PMID: 19678793.

 

Cirillo R, Barone D, Franzone JS. Doxofylline, an antiasthmatic drug lacking affinity for adenosine receptors. Arch Int Pharmacodyn Ther. 1988 Sep-Oct;295:221-37. PMID: 3245738.

" Not dangerous goods.

LKT D5897 Doxycycline Hyclate 1 g 27 Tetracycline; protein translation inhibitor, MMP inhibitor. [4S-(4α,4aα,5α,5aα,6α,12aα)]-4-(Dimethylamino)-1,-4,4a,5,5a,6,11,12a-octahydro-3,5,10,12,12a-penta- hydroxy-6-methyl-1,11-dioxo-2-naphthacenecarbox- amide hydrochloride hemiethanolate hemihydrate Doxycycline hydrochloride hemiethanolate hemihydrate; Atridox; Bassado; Clinofug; Doryx; Hydramycin; Mespafinn; Retens; Spanor; Unacil; Zadorin 24390-14-5 ≥97% 512.9 C22H24N2O8 HCl 1/2(H2O) 1/2(C2H6O)  CCO.CC1C2C(C3C(C(=O)C(=C(C3(C(=O)C2=C(C4=C1C=CC=C4O)O)O)O)C(=O)N)N(C)C)O.CC1C2C(C3C(C(=O)C(=C(C3(C(=O)C2=C(C4=C1C=CC=C4O)O)O)O)C(=O)N)N(C)C)O.O.Cl.Cl Ambient Ambient Soluble in water 50 mg/mL; DMSO. "Joks R, Durkin HG. Non-antibiotic properties of tetracyclines as anti-allergy and asthma drugs. Pharmacol Res. 2011 Dec;64(6):602-9. PMID: 21501686.

 

Dalvi PS, Singh A, Trivedi HR, et al. Effect of doxycycline in patients of moderate to severe chronic obstructive pulmonary disease with stable symptoms. Ann Thorac Med. 2011 Oct;6(4):221-6. PMID: 21977068.

 

Errami M, Galindo CL, Tassa AT, et al. Doxycycline attenuates isoproterenol- and transverse aortic banding-induced cardiac hypertrophy in mice. J Pharmacol Exp Ther. 2008 Mar;324(3):1196-203. PMID: 18089841.

 

Dahl EL, Shock JL, Shenai BR, et al. Tetracyclines specifically target the apicoplast of the malaria parasite Plasmodium falciparum. Antimicrob Agents Chemother. 2006 Sep;50(9):3124-31. PMID: 16940111.

 

Hoerauf A, Mand S, Fischer K, et al. Doxycycline as a novel strategy against bancroftian filariasis-depletion of Wolbachia endosymbionts from Wuchereria bancrofti and stop of microfilaria production. Med Microbiol Immunol. 2003 Nov;192(4):211-6. PMID: 12684759.

 

Dursun D, Kim MC, Solomon A, et al. Treatment of recalcitrant recurrent corneal erosions with inhibitors of matrix metalloproteinase-9, doxycycline and corticosteroids. Am J Ophthalmol. 2001 Jul;132(1):8-13. PMID: 11438047.

 

Fife RS, Sledge GW Jr. Effects of doxycycline on in vitro growth, migration, and gelatinase activity of breast carcinoma cells. J Lab Clin Med. 1995 Mar;125(3):407-11. PMID: 7897308.

 

Fumoto T, Takeshita S, Ito M, Ikeda K. Physiological functions of osteoblast lineage and T cell-derived RANKL in bone homeostasis. J Bone Miner Res. 2014 Apr;29(4):830-842. PMID: 24014480.

" Xn, Xi Not dangerous goods.

LKT D5897 Doxycycline Hyclate 5 g 67 Tetracycline; protein translation inhibitor, MMP inhibitor. [4S-(4α,4aα,5α,5aα,6α,12aα)]-4-(Dimethylamino)-1,-4,4a,5,5a,6,11,12a-octahydro-3,5,10,12,12a-penta- hydroxy-6-methyl-1,11-dioxo-2-naphthacenecarbox- amide hydrochloride hemiethanolate hemihydrate Doxycycline hydrochloride hemiethanolate hemihydrate; Atridox; Bassado; Clinofug; Doryx; Hydramycin; Mespafinn; Retens; Spanor; Unacil; Zadorin 24390-14-5 ≥97% 512.9 C22H24N2O8 HCl 1/2(H2O) 1/2(C2H6O)  CCO.CC1C2C(C3C(C(=O)C(=C(C3(C(=O)C2=C(C4=C1C=CC=C4O)O)O)O)C(=O)N)N(C)C)O.CC1C2C(C3C(C(=O)C(=C(C3(C(=O)C2=C(C4=C1C=CC=C4O)O)O)O)C(=O)N)N(C)C)O.O.Cl.Cl Ambient Ambient Soluble in water 50 mg/mL; DMSO. "Joks R, Durkin HG. Non-antibiotic properties of tetracyclines as anti-allergy and asthma drugs. Pharmacol Res. 2011 Dec;64(6):602-9. PMID: 21501686.

 

Dalvi PS, Singh A, Trivedi HR, et al. Effect of doxycycline in patients of moderate to severe chronic obstructive pulmonary disease with stable symptoms. Ann Thorac Med. 2011 Oct;6(4):221-6. PMID: 21977068.

 

Errami M, Galindo CL, Tassa AT, et al. Doxycycline attenuates isoproterenol- and transverse aortic banding-induced cardiac hypertrophy in mice. J Pharmacol Exp Ther. 2008 Mar;324(3):1196-203. PMID: 18089841.

 

Dahl EL, Shock JL, Shenai BR, et al. Tetracyclines specifically target the apicoplast of the malaria parasite Plasmodium falciparum. Antimicrob Agents Chemother. 2006 Sep;50(9):3124-31. PMID: 16940111.

 

Hoerauf A, Mand S, Fischer K, et al. Doxycycline as a novel strategy against bancroftian filariasis-depletion of Wolbachia endosymbionts from Wuchereria bancrofti and stop of microfilaria production. Med Microbiol Immunol. 2003 Nov;192(4):211-6. PMID: 12684759.

 

Dursun D, Kim MC, Solomon A, et al. Treatment of recalcitrant recurrent corneal erosions with inhibitors of matrix metalloproteinase-9, doxycycline and corticosteroids. Am J Ophthalmol. 2001 Jul;132(1):8-13. PMID: 11438047.

 

Fife RS, Sledge GW Jr. Effects of doxycycline on in vitro growth, migration, and gelatinase activity of breast carcinoma cells. J Lab Clin Med. 1995 Mar;125(3):407-11. PMID: 7897308.

 

Fumoto T, Takeshita S, Ito M, Ikeda K. Physiological functions of osteoblast lineage and T cell-derived RANKL in bone homeostasis. J Bone Miner Res. 2014 Apr;29(4):830-842. PMID: 24014480.

" Xn, Xi Not dangerous goods.

LKT D5897 Doxycycline Hyclate 10 g 120.1 Tetracycline; protein translation inhibitor, MMP inhibitor. [4S-(4α,4aα,5α,5aα,6α,12aα)]-4-(Dimethylamino)-1,-4,4a,5,5a,6,11,12a-octahydro-3,5,10,12,12a-penta- hydroxy-6-methyl-1,11-dioxo-2-naphthacenecarbox- amide hydrochloride hemiethanolate hemihydrate Doxycycline hydrochloride hemiethanolate hemihydrate; Atridox; Bassado; Clinofug; Doryx; Hydramycin; Mespafinn; Retens; Spanor; Unacil; Zadorin 24390-14-5 ≥97% 512.9 C22H24N2O8 HCl 1/2(H2O) 1/2(C2H6O)  CCO.CC1C2C(C3C(C(=O)C(=C(C3(C(=O)C2=C(C4=C1C=CC=C4O)O)O)O)C(=O)N)N(C)C)O.CC1C2C(C3C(C(=O)C(=C(C3(C(=O)C2=C(C4=C1C=CC=C4O)O)O)O)C(=O)N)N(C)C)O.O.Cl.Cl Ambient Ambient Soluble in water 50 mg/mL; DMSO. "Joks R, Durkin HG. Non-antibiotic properties of tetracyclines as anti-allergy and asthma drugs. Pharmacol Res. 2011 Dec;64(6):602-9. PMID: 21501686.

 

Dalvi PS, Singh A, Trivedi HR, et al. Effect of doxycycline in patients of moderate to severe chronic obstructive pulmonary disease with stable symptoms. Ann Thorac Med. 2011 Oct;6(4):221-6. PMID: 21977068.

 

Errami M, Galindo CL, Tassa AT, et al. Doxycycline attenuates isoproterenol- and transverse aortic banding-induced cardiac hypertrophy in mice. J Pharmacol Exp Ther. 2008 Mar;324(3):1196-203. PMID: 18089841.

 

Dahl EL, Shock JL, Shenai BR, et al. Tetracyclines specifically target the apicoplast of the malaria parasite Plasmodium falciparum. Antimicrob Agents Chemother. 2006 Sep;50(9):3124-31. PMID: 16940111.

 

Hoerauf A, Mand S, Fischer K, et al. Doxycycline as a novel strategy against bancroftian filariasis-depletion of Wolbachia endosymbionts from Wuchereria bancrofti and stop of microfilaria production. Med Microbiol Immunol. 2003 Nov;192(4):211-6. PMID: 12684759.

 

Dursun D, Kim MC, Solomon A, et al. Treatment of recalcitrant recurrent corneal erosions with inhibitors of matrix metalloproteinase-9, doxycycline and corticosteroids. Am J Ophthalmol. 2001 Jul;132(1):8-13. PMID: 11438047.

 

Fife RS, Sledge GW Jr. Effects of doxycycline on in vitro growth, migration, and gelatinase activity of breast carcinoma cells. J Lab Clin Med. 1995 Mar;125(3):407-11. PMID: 7897308.

 

Fumoto T, Takeshita S, Ito M, Ikeda K. Physiological functions of osteoblast lineage and T cell-derived RANKL in bone homeostasis. J Bone Miner Res. 2014 Apr;29(4):830-842. PMID: 24014480.

" Xn, Xi Not dangerous goods.

LKT D5897 Doxycycline Hyclate 25 g 213.6 Tetracycline; protein translation inhibitor, MMP inhibitor. [4S-(4α,4aα,5α,5aα,6α,12aα)]-4-(Dimethylamino)-1,-4,4a,5,5a,6,11,12a-octahydro-3,5,10,12,12a-penta- hydroxy-6-methyl-1,11-dioxo-2-naphthacenecarbox- amide hydrochloride hemiethanolate hemihydrate Doxycycline hydrochloride hemiethanolate hemihydrate; Atridox; Bassado; Clinofug; Doryx; Hydramycin; Mespafinn; Retens; Spanor; Unacil; Zadorin 24390-14-5 ≥97% 512.9 C22H24N2O8 HCl 1/2(H2O) 1/2(C2H6O)  CCO.CC1C2C(C3C(C(=O)C(=C(C3(C(=O)C2=C(C4=C1C=CC=C4O)O)O)O)C(=O)N)N(C)C)O.CC1C2C(C3C(C(=O)C(=C(C3(C(=O)C2=C(C4=C1C=CC=C4O)O)O)O)C(=O)N)N(C)C)O.O.Cl.Cl Ambient Ambient Soluble in water 50 mg/mL; DMSO. "Joks R, Durkin HG. Non-antibiotic properties of tetracyclines as anti-allergy and asthma drugs. Pharmacol Res. 2011 Dec;64(6):602-9. PMID: 21501686.

 

Dalvi PS, Singh A, Trivedi HR, et al. Effect of doxycycline in patients of moderate to severe chronic obstructive pulmonary disease with stable symptoms. Ann Thorac Med. 2011 Oct;6(4):221-6. PMID: 21977068.

 

Errami M, Galindo CL, Tassa AT, et al. Doxycycline attenuates isoproterenol- and transverse aortic banding-induced cardiac hypertrophy in mice. J Pharmacol Exp Ther. 2008 Mar;324(3):1196-203. PMID: 18089841.

 

Dahl EL, Shock JL, Shenai BR, et al. Tetracyclines specifically target the apicoplast of the malaria parasite Plasmodium falciparum. Antimicrob Agents Chemother. 2006 Sep;50(9):3124-31. PMID: 16940111.

 

Hoerauf A, Mand S, Fischer K, et al. Doxycycline as a novel strategy against bancroftian filariasis-depletion of Wolbachia endosymbionts from Wuchereria bancrofti and stop of microfilaria production. Med Microbiol Immunol. 2003 Nov;192(4):211-6. PMID: 12684759.

 

Dursun D, Kim MC, Solomon A, et al. Treatment of recalcitrant recurrent corneal erosions with inhibitors of matrix metalloproteinase-9, doxycycline and corticosteroids. Am J Ophthalmol. 2001 Jul;132(1):8-13. PMID: 11438047.

 

Fife RS, Sledge GW Jr. Effects of doxycycline on in vitro growth, migration, and gelatinase activity of breast carcinoma cells. J Lab Clin Med. 1995 Mar;125(3):407-11. PMID: 7897308.

 

Fumoto T, Takeshita S, Ito M, Ikeda K. Physiological functions of osteoblast lineage and T cell-derived RANKL in bone homeostasis. J Bone Miner Res. 2014 Apr;29(4):830-842. PMID: 24014480.

" Xn, Xi Not dangerous goods.

LKT D5898 Doxycycline Monohydrate 1 g 28.7 Tetracycline; protein translation inhibitor, MMP inhibitor. [4S-(4α,4aα,5α,5aα,6α,12aα)]-4-(Dimethylamino)-1,-4,4a,5,5a,6,11,12a-octahydro-3,5,10,12,12a-penta- hydroxy-6-methyl-1,11-dioxo-2-naphthacenecarbox- amide monohydrate Doxycycline; Jenacyclin; Supracyclin; Vibramycin 17086-28-1 ≥97% 462.45 C22H24N2O8 H2O CC1C2C(C3C(C(=O)C(=C(C3(C(=O)C2=C(C4=C1C=CC=C4O)O)O)O)C(=O)N)N(C)C)O.O Ambient Ambient Soluble in ethanol (2 mg/mL) or methanol. "Joks R, Durkin HG. Non-antibiotic properties of tetracyclines as anti-allergy and asthma drugs. Pharmacol Res. 2011 Dec;64(6):602-9. PMID: 21501686.

 

Dalvi PS, Singh A, Trivedi HR, et al. Effect of doxycycline in patients of moderate to severe chronic obstructive pulmonary disease with stable symptoms. Ann Thorac Med. 2011 Oct;6(4):221-6. PMID: 21977068.

 

Errami M, Galindo CL, Tassa AT, et al. Doxycycline attenuates isoproterenol- and transverse aortic banding-induced cardiac hypertrophy in mice. J Pharmacol Exp Ther. 2008 Mar;324(3):1196-203. PMID: 18089841.

 

Dahl EL, Shock JL, Shenai BR, et al. Tetracyclines specifically target the apicoplast of the malaria parasite Plasmodium falciparum. Antimicrob Agents Chemother. 2006 Sep;50(9):3124-31. PMID: 16940111.

 

Hoerauf A, Mand S, Fischer K, et al. Doxycycline as a novel strategy against bancroftian filariasis-depletion of Wolbachia endosymbionts from Wuchereria bancrofti and stop of microfilaria production. Med Microbiol Immunol. 2003 Nov;192(4):211-6. PMID: 12684759.

 

Dursun D, Kim MC, Solomon A, et al. Treatment of recalcitrant recurrent corneal erosions with inhibitors of matrix metalloproteinase-9, doxycycline and corticosteroids. Am J Ophthalmol. 2001 Jul;132(1):8-13. PMID: 11438047.

 

Fife RS, Sledge GW Jr. Effects of doxycycline on in vitro growth, migration, and gelatinase activity of breast carcinoma cells. J Lab Clin Med. 1995 Mar;125(3):407-11. PMID: 7897308.

" Xn, Xi Not dangerous goods.

LKT D5898 Doxycycline Monohydrate 5 g 72.2 Tetracycline; protein translation inhibitor, MMP inhibitor. [4S-(4α,4aα,5α,5aα,6α,12aα)]-4-(Dimethylamino)-1,-4,4a,5,5a,6,11,12a-octahydro-3,5,10,12,12a-penta- hydroxy-6-methyl-1,11-dioxo-2-naphthacenecarbox- amide monohydrate Doxycycline; Jenacyclin; Supracyclin; Vibramycin 17086-28-1 ≥97% 462.45 C22H24N2O8 H2O CC1C2C(C3C(C(=O)C(=C(C3(C(=O)C2=C(C4=C1C=CC=C4O)O)O)O)C(=O)N)N(C)C)O.O Ambient Ambient Soluble in ethanol (2 mg/mL) or methanol. "Joks R, Durkin HG. Non-antibiotic properties of tetracyclines as anti-allergy and asthma drugs. Pharmacol Res. 2011 Dec;64(6):602-9. PMID: 21501686.

 

Dalvi PS, Singh A, Trivedi HR, et al. Effect of doxycycline in patients of moderate to severe chronic obstructive pulmonary disease with stable symptoms. Ann Thorac Med. 2011 Oct;6(4):221-6. PMID: 21977068.

 

Errami M, Galindo CL, Tassa AT, et al. Doxycycline attenuates isoproterenol- and transverse aortic banding-induced cardiac hypertrophy in mice. J Pharmacol Exp Ther. 2008 Mar;324(3):1196-203. PMID: 18089841.

 

Dahl EL, Shock JL, Shenai BR, et al. Tetracyclines specifically target the apicoplast of the malaria parasite Plasmodium falciparum. Antimicrob Agents Chemother. 2006 Sep;50(9):3124-31. PMID: 16940111.

 

Hoerauf A, Mand S, Fischer K, et al. Doxycycline as a novel strategy against bancroftian filariasis-depletion of Wolbachia endosymbionts from Wuchereria bancrofti and stop of microfilaria production. Med Microbiol Immunol. 2003 Nov;192(4):211-6. PMID: 12684759.

 

Dursun D, Kim MC, Solomon A, et al. Treatment of recalcitrant recurrent corneal erosions with inhibitors of matrix metalloproteinase-9, doxycycline and corticosteroids. Am J Ophthalmol. 2001 Jul;132(1):8-13. PMID: 11438047.

 

Fife RS, Sledge GW Jr. Effects of doxycycline on in vitro growth, migration, and gelatinase activity of breast carcinoma cells. J Lab Clin Med. 1995 Mar;125(3):407-11. PMID: 7897308.

" Xn, Xi Not dangerous goods.

LKT D5898 Doxycycline Monohydrate 10 g 130 Tetracycline; protein translation inhibitor, MMP inhibitor. [4S-(4α,4aα,5α,5aα,6α,12aα)]-4-(Dimethylamino)-1,-4,4a,5,5a,6,11,12a-octahydro-3,5,10,12,12a-penta- hydroxy-6-methyl-1,11-dioxo-2-naphthacenecarbox- amide monohydrate Doxycycline; Jenacyclin; Supracyclin; Vibramycin 17086-28-1 ≥97% 462.45 C22H24N2O8 H2O CC1C2C(C3C(C(=O)C(=C(C3(C(=O)C2=C(C4=C1C=CC=C4O)O)O)O)C(=O)N)N(C)C)O.O Ambient Ambient Soluble in ethanol (2 mg/mL) or methanol. "Joks R, Durkin HG. Non-antibiotic properties of tetracyclines as anti-allergy and asthma drugs. Pharmacol Res. 2011 Dec;64(6):602-9. PMID: 21501686.

 

Dalvi PS, Singh A, Trivedi HR, et al. Effect of doxycycline in patients of moderate to severe chronic obstructive pulmonary disease with stable symptoms. Ann Thorac Med. 2011 Oct;6(4):221-6. PMID: 21977068.

 

Errami M, Galindo CL, Tassa AT, et al. Doxycycline attenuates isoproterenol- and transverse aortic banding-induced cardiac hypertrophy in mice. J Pharmacol Exp Ther. 2008 Mar;324(3):1196-203. PMID: 18089841.

 

Dahl EL, Shock JL, Shenai BR, et al. Tetracyclines specifically target the apicoplast of the malaria parasite Plasmodium falciparum. Antimicrob Agents Chemother. 2006 Sep;50(9):3124-31. PMID: 16940111.

 

Hoerauf A, Mand S, Fischer K, et al. Doxycycline as a novel strategy against bancroftian filariasis-depletion of Wolbachia endosymbionts from Wuchereria bancrofti and stop of microfilaria production. Med Microbiol Immunol. 2003 Nov;192(4):211-6. PMID: 12684759.

 

Dursun D, Kim MC, Solomon A, et al. Treatment of recalcitrant recurrent corneal erosions with inhibitors of matrix metalloproteinase-9, doxycycline and corticosteroids. Am J Ophthalmol. 2001 Jul;132(1):8-13. PMID: 11438047.

 

Fife RS, Sledge GW Jr. Effects of doxycycline on in vitro growth, migration, and gelatinase activity of breast carcinoma cells. J Lab Clin Med. 1995 Mar;125(3):407-11. PMID: 7897308.

" Xn, Xi Not dangerous goods.

LKT D5898 Doxycycline Monohydrate 25 g 230.7 Tetracycline; protein translation inhibitor, MMP inhibitor. [4S-(4α,4aα,5α,5aα,6α,12aα)]-4-(Dimethylamino)-1,-4,4a,5,5a,6,11,12a-octahydro-3,5,10,12,12a-penta- hydroxy-6-methyl-1,11-dioxo-2-naphthacenecarbox- amide monohydrate Doxycycline; Jenacyclin; Supracyclin; Vibramycin 17086-28-1 ≥97% 462.45 C22H24N2O8 H2O CC1C2C(C3C(C(=O)C(=C(C3(C(=O)C2=C(C4=C1C=CC=C4O)O)O)O)C(=O)N)N(C)C)O.O Ambient Ambient Soluble in ethanol (2 mg/mL) or methanol. "Joks R, Durkin HG. Non-antibiotic properties of tetracyclines as anti-allergy and asthma drugs. Pharmacol Res. 2011 Dec;64(6):602-9. PMID: 21501686.

 

Dalvi PS, Singh A, Trivedi HR, et al. Effect of doxycycline in patients of moderate to severe chronic obstructive pulmonary disease with stable symptoms. Ann Thorac Med. 2011 Oct;6(4):221-6. PMID: 21977068.

 

Errami M, Galindo CL, Tassa AT, et al. Doxycycline attenuates isoproterenol- and transverse aortic banding-induced cardiac hypertrophy in mice. J Pharmacol Exp Ther. 2008 Mar;324(3):1196-203. PMID: 18089841.

 

Dahl EL, Shock JL, Shenai BR, et al. Tetracyclines specifically target the apicoplast of the malaria parasite Plasmodium falciparum. Antimicrob Agents Chemother. 2006 Sep;50(9):3124-31. PMID: 16940111.

 

Hoerauf A, Mand S, Fischer K, et al. Doxycycline as a novel strategy against bancroftian filariasis-depletion of Wolbachia endosymbionts from Wuchereria bancrofti and stop of microfilaria production. Med Microbiol Immunol. 2003 Nov;192(4):211-6. PMID: 12684759.

 

Dursun D, Kim MC, Solomon A, et al. Treatment of recalcitrant recurrent corneal erosions with inhibitors of matrix metalloproteinase-9, doxycycline and corticosteroids. Am J Ophthalmol. 2001 Jul;132(1):8-13. PMID: 11438047.

 

Fife RS, Sledge GW Jr. Effects of doxycycline on in vitro growth, migration, and gelatinase activity of breast carcinoma cells. J Lab Clin Med. 1995 Mar;125(3):407-11. PMID: 7897308.

" Xn, Xi Not dangerous goods.

LKT D5992 Doxapram Hydrochloride Hydrate 25 mg 80.4 K+ channel blocker, catecholamine release stimulator. 7081-53-0 ≥98% 432.98 C24H30N2O2 HCl H2O CCN1CC(C(C1=O)(C2=CC=CC=C2)C3=CC=CC=C3)CCN4CCOCC4.O.Cl Ambient Ambient "Anderson-Beck R, Wilson L, Brazier S, et al. Doxapram stimulates dopamine release from the intact rat carotid body in vitro. Neurosci Lett. 1995 Feb 24;187(1):25-8. PMID: 7617294.

 

Peers C. Effects of doxapram on ionic currents recorded in isolated type I cells of the neonatal rat carotid body. Brain Res. 1991 Dec 24;568(1-2):116-22. PMID: 1667613.

 

Pollard BJ, Randall NP, Pleuvry BJ. Doxapram and the neuromuscular junction. Br J Anaesth. 1989 Jun;62(6):664-8. PMID: 2751921.

" T "UN number: 2811     Class:  6.1     Packing group:  III 

Proper shipping name:  Toxic solid, organic, n.o.s. (Doxapram Hydrochloride Hydrate)"

LKT D5992 Doxapram Hydrochloride Hydrate 100 mg 251.3 K+ channel blocker, catecholamine release stimulator. 7081-53-0 ≥98% 432.98 C24H30N2O2 HCl H2O CCN1CC(C(C1=O)(C2=CC=CC=C2)C3=CC=CC=C3)CCN4CCOCC4.O.Cl Ambient Ambient "Anderson-Beck R, Wilson L, Brazier S, et al. Doxapram stimulates dopamine release from the intact rat carotid body in vitro. Neurosci Lett. 1995 Feb 24;187(1):25-8. PMID: 7617294.

 

Peers C. Effects of doxapram on ionic currents recorded in isolated type I cells of the neonatal rat carotid body. Brain Res. 1991 Dec 24;568(1-2):116-22. PMID: 1667613.

 

Pollard BJ, Randall NP, Pleuvry BJ. Doxapram and the neuromuscular junction. Br J Anaesth. 1989 Jun;62(6):664-8. PMID: 2751921.

" T "UN number: 2811     Class:  6.1     Packing group:  III 

Proper shipping name:  Toxic solid, organic, n.o.s. (Doxapram Hydrochloride Hydrate)"

LKT D5992 Doxapram Hydrochloride Hydrate 500 mg 1046.4 K+ channel blocker, catecholamine release stimulator. 7081-53-0 ≥98% 432.98 C24H30N2O2 HCl H2O CCN1CC(C(C1=O)(C2=CC=CC=C2)C3=CC=CC=C3)CCN4CCOCC4.O.Cl Ambient Ambient "Anderson-Beck R, Wilson L, Brazier S, et al. Doxapram stimulates dopamine release from the intact rat carotid body in vitro. Neurosci Lett. 1995 Feb 24;187(1):25-8. PMID: 7617294.

 

Peers C. Effects of doxapram on ionic currents recorded in isolated type I cells of the neonatal rat carotid body. Brain Res. 1991 Dec 24;568(1-2):116-22. PMID: 1667613.

 

Pollard BJ, Randall NP, Pleuvry BJ. Doxapram and the neuromuscular junction. Br J Anaesth. 1989 Jun;62(6):664-8. PMID: 2751921.

" T "UN number: 2811     Class:  6.1     Packing group:  III 

Proper shipping name:  Toxic solid, organic, n.o.s. (Doxapram Hydrochloride Hydrate)"

LKT D6957 Droloxifene 25 mg 121.9 Triphenylthylene, tamoxifen analog; SERM. 3-Hydroxytamoxifen 82413-20-5 ≥98% 387.51 C26H29NO2 CCC(=C(C1=CC=C(C=C1)OCCN(C)C)C2=CC(=CC=C2)O)C3=CC=CC=C3 Ambient Ambient "Shelly W, Draper MW, Krishnan V, et al. Selective estrogen receptor modulators: an update on recent clinical findings. Obstet Gynecol Surv. 2008 Mar;63(3):163-81. PMID: 18279543.

 

Martin JH, Symonds A, Chohan S. Down-regulation of nitric oxide production by droloxifene and toremifene in human breast cancer cells. Oncol Rep. 2003 Jul-Aug;10(4):979-84. PMID: 12792756

 

Herrington DM, Brosnihan KB, Pusser BE, et al. Differential effects of E and droloxifene on C-reactive protein and other markers of inflammation in healthy postmenopausal women. J Clin Endocrinol Metab. 2001 Sep;86(9):4216-22. PMID: 11549652.

 

Leng Y, Feng Y, Cao L, et al. Effects of droloxifene on apoptosis and Bax, Bcl-2 protein expression of luteal cells in pseudopregnant rats. Acta Pharmacol Sin. 2001 Feb;22(2):155-62. PMID: 11741521.

 

Leng Y, Gu ZP, Cao L. Apoptosis induced by droloxifene and c-myc, bax and bcl-2 mRNA expression in cultured luteal cells of rats. Eur J Pharmacol. 2000 Dec 8;409(2):123-31. PMID: 11104825.

 

Knabbe C, Zugmaier G, Schmahl M, et al. Induction of transforming growth factor beta by the antiestrogens droloxifene, tamoxifen, and toremifene in MCF-7 cells. Am J Clin Oncol. 1991;14 Suppl 2:S15-20. PMID: 1835818.

" "UN number: 3077     Class: 9     Packing group: III       

Proper shipping name: Environementally hazardous substance, solid, N.O.S. (Droloxifene)"

LKT D6957 Droloxifene 100 mg 375.1 Triphenylthylene, tamoxifen analog; SERM. 3-Hydroxytamoxifen 82413-20-5 ≥98% 387.51 C26H29NO2 CCC(=C(C1=CC=C(C=C1)OCCN(C)C)C2=CC(=CC=C2)O)C3=CC=CC=C3 Ambient Ambient "Shelly W, Draper MW, Krishnan V, et al. Selective estrogen receptor modulators: an update on recent clinical findings. Obstet Gynecol Surv. 2008 Mar;63(3):163-81. PMID: 18279543.

 

Martin JH, Symonds A, Chohan S. Down-regulation of nitric oxide production by droloxifene and toremifene in human breast cancer cells. Oncol Rep. 2003 Jul-Aug;10(4):979-84. PMID: 12792756

 

Herrington DM, Brosnihan KB, Pusser BE, et al. Differential effects of E and droloxifene on C-reactive protein and other markers of inflammation in healthy postmenopausal women. J Clin Endocrinol Metab. 2001 Sep;86(9):4216-22. PMID: 11549652.

 

Leng Y, Feng Y, Cao L, et al. Effects of droloxifene on apoptosis and Bax, Bcl-2 protein expression of luteal cells in pseudopregnant rats. Acta Pharmacol Sin. 2001 Feb;22(2):155-62. PMID: 11741521.

 

Leng Y, Gu ZP, Cao L. Apoptosis induced by droloxifene and c-myc, bax and bcl-2 mRNA expression in cultured luteal cells of rats. Eur J Pharmacol. 2000 Dec 8;409(2):123-31. PMID: 11104825.

 

Knabbe C, Zugmaier G, Schmahl M, et al. Induction of transforming growth factor beta by the antiestrogens droloxifene, tamoxifen, and toremifene in MCF-7 cells. Am J Clin Oncol. 1991;14 Suppl 2:S15-20. PMID: 1835818.

" "UN number: 3077     Class: 9     Packing group: III       

Proper shipping name: Environementally hazardous substance, solid, N.O.S. (Droloxifene)"

LKT D6957 Droloxifene 250 mg 656.3 Triphenylthylene, tamoxifen analog; SERM. 3-Hydroxytamoxifen 82413-20-5 ≥98% 387.51 C26H29NO2 CCC(=C(C1=CC=C(C=C1)OCCN(C)C)C2=CC(=CC=C2)O)C3=CC=CC=C3 Ambient Ambient "Shelly W, Draper MW, Krishnan V, et al. Selective estrogen receptor modulators: an update on recent clinical findings. Obstet Gynecol Surv. 2008 Mar;63(3):163-81. PMID: 18279543.

 

Martin JH, Symonds A, Chohan S. Down-regulation of nitric oxide production by droloxifene and toremifene in human breast cancer cells. Oncol Rep. 2003 Jul-Aug;10(4):979-84. PMID: 12792756

 

Herrington DM, Brosnihan KB, Pusser BE, et al. Differential effects of E and droloxifene on C-reactive protein and other markers of inflammation in healthy postmenopausal women. J Clin Endocrinol Metab. 2001 Sep;86(9):4216-22. PMID: 11549652.

 

Leng Y, Feng Y, Cao L, et al. Effects of droloxifene on apoptosis and Bax, Bcl-2 protein expression of luteal cells in pseudopregnant rats. Acta Pharmacol Sin. 2001 Feb;22(2):155-62. PMID: 11741521.

 

Leng Y, Gu ZP, Cao L. Apoptosis induced by droloxifene and c-myc, bax and bcl-2 mRNA expression in cultured luteal cells of rats. Eur J Pharmacol. 2000 Dec 8;409(2):123-31. PMID: 11104825.

 

Knabbe C, Zugmaier G, Schmahl M, et al. Induction of transforming growth factor beta by the antiestrogens droloxifene, tamoxifen, and toremifene in MCF-7 cells. Am J Clin Oncol. 1991;14 Suppl 2:S15-20. PMID: 1835818.

" "UN number: 3077     Class: 9     Packing group: III       

Proper shipping name: Environementally hazardous substance, solid, N.O.S. (Droloxifene)"

LKT D6958 Droloxifene Citrate 25 mg 121.9 Tamoxifen analog; SERM. 97752-20-0  ≥98% 579.64 C26H29NO2 C6H8O7 CCC(=C(C1=CC=C(C=C1)OCCN(C)C)C2=CC(=CC=C2)O)C3=CC=CC=C3.C(C(=O)O)C(CC(=O)O)(C(=O)O)O Ambient Ambient "Shelly W, Draper MW, Krishnan V, et al. Selective estrogen receptor modulators: an update on recent clinical findings. Obstet Gynecol Surv. 2008 Mar;63(3):163-81. PMID: 18279543.

 

Martin JH, Symonds A, Chohan S. Down-regulation of nitric oxide production by droloxifene and toremifene in human breast cancer cells. Oncol Rep. 2003 Jul-Aug;10(4):979-84. PMID: 12792756

 

Herrington DM, Brosnihan KB, Pusser BE, et al. Differential effects of E and droloxifene on C-reactive protein and other markers of inflammation in healthy postmenopausal women. J Clin Endocrinol Metab. 2001 Sep;86(9):4216-22. PMID: 11549652.

 

Leng Y, Feng Y, Cao L, et al. Effects of droloxifene on apoptosis and Bax, Bcl-2 protein expression of luteal cells in pseudopregnant rats. Acta Pharmacol Sin. 2001 Feb;22(2):155-62. PMID: 11741521.

 

Leng Y, Gu ZP, Cao L. Apoptosis induced by droloxifene and c-myc, bax and bcl-2 mRNA expression in cultured luteal cells of rats. Eur J Pharmacol. 2000 Dec 8;409(2):123-31. PMID: 11104825.

 

Knabbe C, Zugmaier G, Schmahl M, et al. Induction of transforming growth factor beta by the antiestrogens droloxifene, tamoxifen, and toremifene in MCF-7 cells. Am J Clin Oncol. 1991;14 Suppl 2:S15-20. PMID: 1835818.

" Not dangerous goods.

LKT D6958 Droloxifene Citrate 100 mg 375.1 Tamoxifen analog; SERM. 97752-20-0  ≥98% 579.64 C26H29NO2 C6H8O7 CCC(=C(C1=CC=C(C=C1)OCCN(C)C)C2=CC(=CC=C2)O)C3=CC=CC=C3.C(C(=O)O)C(CC(=O)O)(C(=O)O)O Ambient Ambient "Shelly W, Draper MW, Krishnan V, et al. Selective estrogen receptor modulators: an update on recent clinical findings. Obstet Gynecol Surv. 2008 Mar;63(3):163-81. PMID: 18279543.

 

Martin JH, Symonds A, Chohan S. Down-regulation of nitric oxide production by droloxifene and toremifene in human breast cancer cells. Oncol Rep. 2003 Jul-Aug;10(4):979-84. PMID: 12792756

 

Herrington DM, Brosnihan KB, Pusser BE, et al. Differential effects of E and droloxifene on C-reactive protein and other markers of inflammation in healthy postmenopausal women. J Clin Endocrinol Metab. 2001 Sep;86(9):4216-22. PMID: 11549652.

 

Leng Y, Feng Y, Cao L, et al. Effects of droloxifene on apoptosis and Bax, Bcl-2 protein expression of luteal cells in pseudopregnant rats. Acta Pharmacol Sin. 2001 Feb;22(2):155-62. PMID: 11741521.

 

Leng Y, Gu ZP, Cao L. Apoptosis induced by droloxifene and c-myc, bax and bcl-2 mRNA expression in cultured luteal cells of rats. Eur J Pharmacol. 2000 Dec 8;409(2):123-31. PMID: 11104825.

 

Knabbe C, Zugmaier G, Schmahl M, et al. Induction of transforming growth factor beta by the antiestrogens droloxifene, tamoxifen, and toremifene in MCF-7 cells. Am J Clin Oncol. 1991;14 Suppl 2:S15-20. PMID: 1835818.

" Not dangerous goods.

LKT D6958 Droloxifene Citrate 250 mg 656.3 Tamoxifen analog; SERM. 97752-20-0  ≥98% 579.64 C26H29NO2 C6H8O7 CCC(=C(C1=CC=C(C=C1)OCCN(C)C)C2=CC(=CC=C2)O)C3=CC=CC=C3.C(C(=O)O)C(CC(=O)O)(C(=O)O)O Ambient Ambient "Shelly W, Draper MW, Krishnan V, et al. Selective estrogen receptor modulators: an update on recent clinical findings. Obstet Gynecol Surv. 2008 Mar;63(3):163-81. PMID: 18279543.

 

Martin JH, Symonds A, Chohan S. Down-regulation of nitric oxide production by droloxifene and toremifene in human breast cancer cells. Oncol Rep. 2003 Jul-Aug;10(4):979-84. PMID: 12792756

 

Herrington DM, Brosnihan KB, Pusser BE, et al. Differential effects of E and droloxifene on C-reactive protein and other markers of inflammation in healthy postmenopausal women. J Clin Endocrinol Metab. 2001 Sep;86(9):4216-22. PMID: 11549652.

 

Leng Y, Feng Y, Cao L, et al. Effects of droloxifene on apoptosis and Bax, Bcl-2 protein expression of luteal cells in pseudopregnant rats. Acta Pharmacol Sin. 2001 Feb;22(2):155-62. PMID: 11741521.

 

Leng Y, Gu ZP, Cao L. Apoptosis induced by droloxifene and c-myc, bax and bcl-2 mRNA expression in cultured luteal cells of rats. Eur J Pharmacol. 2000 Dec 8;409(2):123-31. PMID: 11104825.

 

Knabbe C, Zugmaier G, Schmahl M, et al. Induction of transforming growth factor beta by the antiestrogens droloxifene, tamoxifen, and toremifene in MCF-7 cells. Am J Clin Oncol. 1991;14 Suppl 2:S15-20. PMID: 1835818.

" Not dangerous goods.

LKT T5672 Tosufloxacin Tosylate 100 mg 47.6 Fluoroquinolone; topoisomerase IV and bacterial DNA gyrase inhibitor. 7-(3-Amino-1-pyrrolidinyl)-1-(2,4-difluorophenyl)-6- fluoro-1,4-dihydro-4-oxo-1,8-naphthyridine-3- carboxylic acid toluenesulfonate Tosufloxacin toluenesulfonate; Ozex; Tosuxacin 115964-29-9 ≥98% 576.55 C19H15F3N4O3 C7H8O3S CC1=CC=C(C=C1)S(=O)(=O)O.C1CN(CC1N)C2=C(C=C3C(=O)C(=CN(C3=N2)C4=C(C=C(C=C4)F)F)C(=O)O)F Ambient Ambient Very slighlty soluble in water. "Akaike H, Miyashita N, Kubo M, et al. In vitro activities of 11 antimicrobial agents against macrolide-resistant Mycoplasma pneumoniae isolates from pediatric patients: results from a multicenter surveillance study. Jpn J Infect Dis. 2012;65(6):535-8. PMID: 23183207.

 

Ayaki M, Iwasawa A, Soda M, et al. Cytotoxicity of five fluoroquinolone and two nonsteroidal anti-inflammatory benzalkonium chloride-free ophthalmic solutions in four corneoconjunctival cell lines. Clin Ophthalmol. 2010 Sep 20;4:1019-24. PMID: 20922036.

 

Tanaka M, Onodera Y, Uchida Y, et al. Inhibitory activities of quinolones against DNA gyrase and topoisomerase IV purified from Staphylococcus aureus. Antimicrob Agents Chemother. 1997 Nov;41(11):2362-6. PMID: 9371334.

" Not dangerous goods.

LKT T5672 Tosufloxacin Tosylate 500 mg 108.8 Fluoroquinolone; topoisomerase IV and bacterial DNA gyrase inhibitor. 7-(3-Amino-1-pyrrolidinyl)-1-(2,4-difluorophenyl)-6- fluoro-1,4-dihydro-4-oxo-1,8-naphthyridine-3- carboxylic acid toluenesulfonate Tosufloxacin toluenesulfonate; Ozex; Tosuxacin 115964-29-9 ≥98% 576.55 C19H15F3N4O3 C7H8O3S CC1=CC=C(C=C1)S(=O)(=O)O.C1CN(CC1N)C2=C(C=C3C(=O)C(=CN(C3=N2)C4=C(C=C(C=C4)F)F)C(=O)O)F Ambient Ambient Very slighlty soluble in water. "Akaike H, Miyashita N, Kubo M, et al. In vitro activities of 11 antimicrobial agents against macrolide-resistant Mycoplasma pneumoniae isolates from pediatric patients: results from a multicenter surveillance study. Jpn J Infect Dis. 2012;65(6):535-8. PMID: 23183207.

 

Ayaki M, Iwasawa A, Soda M, et al. Cytotoxicity of five fluoroquinolone and two nonsteroidal anti-inflammatory benzalkonium chloride-free ophthalmic solutions in four corneoconjunctival cell lines. Clin Ophthalmol. 2010 Sep 20;4:1019-24. PMID: 20922036.

 

Tanaka M, Onodera Y, Uchida Y, et al. Inhibitory activities of quinolones against DNA gyrase and topoisomerase IV purified from Staphylococcus aureus. Antimicrob Agents Chemother. 1997 Nov;41(11):2362-6. PMID: 9371334.

" Not dangerous goods.

LKT T5672 Tosufloxacin Tosylate 1 g 203.8 Fluoroquinolone; topoisomerase IV and bacterial DNA gyrase inhibitor. 7-(3-Amino-1-pyrrolidinyl)-1-(2,4-difluorophenyl)-6- fluoro-1,4-dihydro-4-oxo-1,8-naphthyridine-3- carboxylic acid toluenesulfonate Tosufloxacin toluenesulfonate; Ozex; Tosuxacin 115964-29-9 ≥98% 576.55 C19H15F3N4O3 C7H8O3S CC1=CC=C(C=C1)S(=O)(=O)O.C1CN(CC1N)C2=C(C=C3C(=O)C(=CN(C3=N2)C4=C(C=C(C=C4)F)F)C(=O)O)F Ambient Ambient Very slighlty soluble in water. "Akaike H, Miyashita N, Kubo M, et al. In vitro activities of 11 antimicrobial agents against macrolide-resistant Mycoplasma pneumoniae isolates from pediatric patients: results from a multicenter surveillance study. Jpn J Infect Dis. 2012;65(6):535-8. PMID: 23183207.

 

Ayaki M, Iwasawa A, Soda M, et al. Cytotoxicity of five fluoroquinolone and two nonsteroidal anti-inflammatory benzalkonium chloride-free ophthalmic solutions in four corneoconjunctival cell lines. Clin Ophthalmol. 2010 Sep 20;4:1019-24. PMID: 20922036.

 

Tanaka M, Onodera Y, Uchida Y, et al. Inhibitory activities of quinolones against DNA gyrase and topoisomerase IV purified from Staphylococcus aureus. Antimicrob Agents Chemother. 1997 Nov;41(11):2362-6. PMID: 9371334.

" Not dangerous goods.

LKT E0073 Ebselen 5 mg 65.6 Synthetic glutathione peroxidase mimetic; yeast sporulation inhibitor. 2-Phenyl-1,2-benzisoselenazolin-3-one 60940-34-3 ≥98% 274.18 C13H9NOSe C1=CC=C(C=C1)N2C(=O)C3=CC=CC=C3[Se]2 Ambient -20°C Soluble in DMSO. "Azad GK, Singh V, Mandal P, et al. Ebselen induces reactive oxygen species (ROS)-mediated cytotoxicity in Saccharomyces cerevisiae with inhibition of glutamate dehydrogenase being a target. FEBS Open Bio. 2014 Jan 6;4:77-89. PMID: 24490132.

 

Favrot L, Grzegorzewicz AE, Lajiness DH, et al. Mechanism of inhibition of Mycobacterium tuberculosis antigen 85 by ebselen. Nat Commun. 2013;4:2748. PMID: 24193546.

 

Mahadevan J, Parazzoli S, Oseid E, et al. Ebselen treatment prevents islet apoptosis, maintains intranuclear Pdx-1 and MafA levels, and preserves β-cell mass and function in ZDF rats. Diabetes. 2013 Oct;62(10):3582-8. PMID: 23801580.

" T, N "UN number: 3283     Class: 6.1     Packing Group: III

Proper shipping name: Selenium compound, solid, n.o.s. (Ebselen)"

LKT E0073 Ebselen 25 mg 149.9 Synthetic glutathione peroxidase mimetic; yeast sporulation inhibitor. 2-Phenyl-1,2-benzisoselenazolin-3-one 60940-34-3 ≥98% 274.18 C13H9NOSe C1=CC=C(C=C1)N2C(=O)C3=CC=CC=C3[Se]2 Ambient -20°C Soluble in DMSO. "Azad GK, Singh V, Mandal P, et al. Ebselen induces reactive oxygen species (ROS)-mediated cytotoxicity in Saccharomyces cerevisiae with inhibition of glutamate dehydrogenase being a target. FEBS Open Bio. 2014 Jan 6;4:77-89. PMID: 24490132.

 

Favrot L, Grzegorzewicz AE, Lajiness DH, et al. Mechanism of inhibition of Mycobacterium tuberculosis antigen 85 by ebselen. Nat Commun. 2013;4:2748. PMID: 24193546.

 

Mahadevan J, Parazzoli S, Oseid E, et al. Ebselen treatment prevents islet apoptosis, maintains intranuclear Pdx-1 and MafA levels, and preserves β-cell mass and function in ZDF rats. Diabetes. 2013 Oct;62(10):3582-8. PMID: 23801580.

" T, N "UN number: 3283     Class: 6.1     Packing Group: III

Proper shipping name: Selenium compound, solid, n.o.s. (Ebselen)"

LKT E0403 Ebastine 1 g 93.8 Histamine H1 antagonist. 90729-43-4 ≥98% 469.66 C32H39NO2 CC(C)(C)C1=CC=C(C=C1)C(=O)CCCN2CCC(CC2)OC(C3=CC=CC=C3)C4=CC=CC=C4 Ambient Ambient "Ciprandi G. Clinical utility and patient adherence with ebastine for allergic rhinitis. Patient Prefer Adherence. 2010 Oct 14;4:389-95. PMID: 21206514.

 

Ciprandi G, Cirillo I, Pistorio A, et al. Ebastine increases IFN-gamma production in patients with persistent allergic rhinitis. J Biol Regul Homeost Agents. 2009 Jan-Mar;23(1):31-6. PMID: 19321044.

 

Tagawa M, Kano M, Okamura N, et al. Neuroimaging of histamine H1-receptor occupancy in human brain by positron emission tomography (PET): a comparative study of ebastine, a second-generation antihistamine, and (+)-chlorpheniramine, a classical antihistamine. Br J Clin Pharmacol. 2001 Nov;52(5):501-9. PMID: 11736858.

" None Not dangerous goods.

LKT E0403 Ebastine 5 g 375.1 Histamine H1 antagonist. 90729-43-4 ≥98% 469.66 C32H39NO2 CC(C)(C)C1=CC=C(C=C1)C(=O)CCCN2CCC(CC2)OC(C3=CC=CC=C3)C4=CC=CC=C4 Ambient Ambient "Ciprandi G. Clinical utility and patient adherence with ebastine for allergic rhinitis. Patient Prefer Adherence. 2010 Oct 14;4:389-95. PMID: 21206514.

 

Ciprandi G, Cirillo I, Pistorio A, et al. Ebastine increases IFN-gamma production in patients with persistent allergic rhinitis. J Biol Regul Homeost Agents. 2009 Jan-Mar;23(1):31-6. PMID: 19321044.

 

Tagawa M, Kano M, Okamura N, et al. Neuroimaging of histamine H1-receptor occupancy in human brain by positron emission tomography (PET): a comparative study of ebastine, a second-generation antihistamine, and (+)-chlorpheniramine, a classical antihistamine. Br J Clin Pharmacol. 2001 Nov;52(5):501-9. PMID: 11736858.

" None Not dangerous goods.

LKT E0813 Ecdysterone 5 mg 67.9 Natural steroid hormone produced by arthropods; ecdysone agonist. (2β,3β,5β,22R)-2,3,14,20,22,25-Hexahydroxycholest- 7-en-6-one 20-Hydroxyecdysone; Crustecdysone; Isoinokosterone; Polypodine A 5289-74-7 ≥96% 480.64 C27H44O7 CC12CCC3C(=CC(=O)C4C3(CC(C(C4)O)O)C)C1(CCC2C(C)(C(CCC(C)(C)O)O)O)O Store under nitrogen. Ambient -20°C Soluble in alcohol. "Liu H, Jia Q, Tettamanti G, et al. Balancing crosstalk between 20-hydroxyecdysone-induced autophagy and caspase activity in the fat body during Drosophila larval-prepupal transition. Insect Biochem Mol Biol. 2013 Nov;43(11):1068-78. PMID: 24036278.

 

Volodin VV, Sidorova IuS, Mazo VK. 20-Hydroxyecdysone--plant adaptogen: an anabolic effect, possible use in sports nutrition. Vopr Pitan. 2013;82(6):24-30. PMID: 24741953.

 

Luo C, Yi B, Fan W, et al. Enhanced angiogenesis and astrocyte activation by ecdysterone treatment in a focal cerebral ischemia rat model. Acta Neurochir Suppl. 2011;110(Pt 1):151-5. PMID: 21116931.

" None Not dangerous goods.

LKT E0813 Ecdysterone 10 mg 95.1 Natural steroid hormone produced by arthropods; ecdysone agonist. (2β,3β,5β,22R)-2,3,14,20,22,25-Hexahydroxycholest- 7-en-6-one 20-Hydroxyecdysone; Crustecdysone; Isoinokosterone; Polypodine A 5289-74-7 ≥96% 480.64 C27H44O7 CC12CCC3C(=CC(=O)C4C3(CC(C(C4)O)O)C)C1(CCC2C(C)(C(CCC(C)(C)O)O)O)O Store under nitrogen. Ambient -20°C Soluble in alcohol. "Liu H, Jia Q, Tettamanti G, et al. Balancing crosstalk between 20-hydroxyecdysone-induced autophagy and caspase activity in the fat body during Drosophila larval-prepupal transition. Insect Biochem Mol Biol. 2013 Nov;43(11):1068-78. PMID: 24036278.

 

Volodin VV, Sidorova IuS, Mazo VK. 20-Hydroxyecdysone--plant adaptogen: an anabolic effect, possible use in sports nutrition. Vopr Pitan. 2013;82(6):24-30. PMID: 24741953.

 

Luo C, Yi B, Fan W, et al. Enhanced angiogenesis and astrocyte activation by ecdysterone treatment in a focal cerebral ischemia rat model. Acta Neurochir Suppl. 2011;110(Pt 1):151-5. PMID: 21116931.

" None Not dangerous goods.

LKT E0813 Ecdysterone 25 mg 183.4 Natural steroid hormone produced by arthropods; ecdysone agonist. (2β,3β,5β,22R)-2,3,14,20,22,25-Hexahydroxycholest- 7-en-6-one 20-Hydroxyecdysone; Crustecdysone; Isoinokosterone; Polypodine A 5289-74-7 ≥96% 480.64 C27H44O7 CC12CCC3C(=CC(=O)C4C3(CC(C(C4)O)O)C)C1(CCC2C(C)(C(CCC(C)(C)O)O)O)O Store under nitrogen. Ambient -20°C Soluble in alcohol. "Liu H, Jia Q, Tettamanti G, et al. Balancing crosstalk between 20-hydroxyecdysone-induced autophagy and caspase activity in the fat body during Drosophila larval-prepupal transition. Insect Biochem Mol Biol. 2013 Nov;43(11):1068-78. PMID: 24036278.

 

Volodin VV, Sidorova IuS, Mazo VK. 20-Hydroxyecdysone--plant adaptogen: an anabolic effect, possible use in sports nutrition. Vopr Pitan. 2013;82(6):24-30. PMID: 24741953.

 

Luo C, Yi B, Fan W, et al. Enhanced angiogenesis and astrocyte activation by ecdysterone treatment in a focal cerebral ischemia rat model. Acta Neurochir Suppl. 2011;110(Pt 1):151-5. PMID: 21116931.

" None Not dangerous goods.

LKT E2424 Egg Laying Hormone (from Aplysia) 0.5 mg 255 Peptide found in Aplysia. 117680-39-4 ≥95% 4384.17 C190H329N59O57S1 Ambient -20°C "Hickey CM, Groten CJ, Sham L, et al. Voltage-gated Ca2+ influx and mitochondrial Ca2+ initiate secretion from Aplysia neuroendocrine cells. Neuroscience. 2013 Oct 10;250:755-72. PMID: 23876326.

 

Li L, Garden RW, Floyd PD, et al. Egg-laying hormone peptides in the aplysiidae family. J Exp Biol. 1999 Nov;202(Pt 21):2961-73. PMID: 10518477.

"

LKT E2424 Egg Laying Hormone (from Aplysia) 1 mg 433.5 Peptide found in Aplysia. 117680-39-4 ≥95% 4384.17 C190H329N59O57S1 Ambient -20°C "Hickey CM, Groten CJ, Sham L, et al. Voltage-gated Ca2+ influx and mitochondrial Ca2+ initiate secretion from Aplysia neuroendocrine cells. Neuroscience. 2013 Oct 10;250:755-72. PMID: 23876326.

 

Li L, Garden RW, Floyd PD, et al. Egg-laying hormone peptides in the aplysiidae family. J Exp Biol. 1999 Nov;202(Pt 21):2961-73. PMID: 10518477.

"

LKT E2424 Egg Laying Hormone (from Aplysia) 2.5 mg 820.9 Peptide found in Aplysia. 117680-39-4 ≥95% 4384.17 C190H329N59O57S1 Ambient -20°C "Hickey CM, Groten CJ, Sham L, et al. Voltage-gated Ca2+ influx and mitochondrial Ca2+ initiate secretion from Aplysia neuroendocrine cells. Neuroscience. 2013 Oct 10;250:755-72. PMID: 23876326.

 

Li L, Garden RW, Floyd PD, et al. Egg-laying hormone peptides in the aplysiidae family. J Exp Biol. 1999 Nov;202(Pt 21):2961-73. PMID: 10518477.

"

LKT E2542 Met-Enkephalin Amide 10 mg 63 Endogenous opioid peptide; δOR and μOR agonist. Enkephalinamide-met-, Methionine enkephalinamide 60117-17-1 ≥95% 572.69 C27H36N6O6S CSCCC(C(=O)N)NC(=O)C(CC1=CC=CC=C1)NC(=O)CNC(=O)CNC(=O)C(CC2=CC=C(C=C2)O)N Ambient -20°C "Gonzalez-Nunez V, Jimenez González A, Barreto-Valer K, et al. In vivo regulation of the μ opioid receptor: role of the endogenous opioid agents. Mol Med. 2013 Mar 5;19:7-17. PMID: 23348513.

 

Fanning RA, McMorrow JP, Campion DP, et al. Opioid mediated activity and expression of mu and delta opioid receptors in isolated human term non-labouring myometrium. Eur J Pharmacol. 2013 Jan 5;698(1-3):170-7. PMID: 23051674.

 

Hadjiconstantinou M, Neff NH. Nicotine and endogenous opioids: neurochemical and pharmacological evidence. Neuropharmacology. 2011 Jun;60(7-8):1209-20. PMID: 21108953.

 

Stagg NJ, Mata HP, Ibrahim MM, et al. Regular exercise reverses sensory hypersensitivity in a rat neuropathic pain model: role of endogenous opioids. Anesthesiology. 2011 Apr;114(4):940-8. PMID: 21386701.

 

Gredicak M, Supek F, Kralj M, et al. Computational structure-activity study directs synthesis of novel antitumor enkephalin analogs. Amino Acids. 2010 Apr;38(4):1185-91. PMID: 19639251.

 

Lee HK, Smith MD, Smith BJ, et al. Anticonvulsant Met-enkephalin analogues containing backbone spacers reveal alternative non-opioid signaling in the brain. ACS Chem Biol. 2009 Aug 21;4(8):659-71. PMID: 19634861.

" Not dangerous goods.

LKT E2542 Met-Enkephalin Amide 20 mg 104.9 Endogenous opioid peptide; δOR and μOR agonist. Enkephalinamide-met-, Methionine enkephalinamide 60117-17-1 ≥95% 572.69 C27H36N6O6S CSCCC(C(=O)N)NC(=O)C(CC1=CC=CC=C1)NC(=O)CNC(=O)CNC(=O)C(CC2=CC=C(C=C2)O)N Ambient -20°C "Gonzalez-Nunez V, Jimenez González A, Barreto-Valer K, et al. In vivo regulation of the μ opioid receptor: role of the endogenous opioid agents. Mol Med. 2013 Mar 5;19:7-17. PMID: 23348513.

 

Fanning RA, McMorrow JP, Campion DP, et al. Opioid mediated activity and expression of mu and delta opioid receptors in isolated human term non-labouring myometrium. Eur J Pharmacol. 2013 Jan 5;698(1-3):170-7. PMID: 23051674.

 

Hadjiconstantinou M, Neff NH. Nicotine and endogenous opioids: neurochemical and pharmacological evidence. Neuropharmacology. 2011 Jun;60(7-8):1209-20. PMID: 21108953.

 

Stagg NJ, Mata HP, Ibrahim MM, et al. Regular exercise reverses sensory hypersensitivity in a rat neuropathic pain model: role of endogenous opioids. Anesthesiology. 2011 Apr;114(4):940-8. PMID: 21386701.

 

Gredicak M, Supek F, Kralj M, et al. Computational structure-activity study directs synthesis of novel antitumor enkephalin analogs. Amino Acids. 2010 Apr;38(4):1185-91. PMID: 19639251.

 

Lee HK, Smith MD, Smith BJ, et al. Anticonvulsant Met-enkephalin analogues containing backbone spacers reveal alternative non-opioid signaling in the brain. ACS Chem Biol. 2009 Aug 21;4(8):659-71. PMID: 19634861.

" Not dangerous goods.

LKT E2542 Met-Enkephalin Amide 50 mg 186 Endogenous opioid peptide; δOR and μOR agonist. Enkephalinamide-met-, Methionine enkephalinamide 60117-17-1 ≥95% 572.69 C27H36N6O6S CSCCC(C(=O)N)NC(=O)C(CC1=CC=CC=C1)NC(=O)CNC(=O)CNC(=O)C(CC2=CC=C(C=C2)O)N Ambient -20°C "Gonzalez-Nunez V, Jimenez González A, Barreto-Valer K, et al. In vivo regulation of the μ opioid receptor: role of the endogenous opioid agents. Mol Med. 2013 Mar 5;19:7-17. PMID: 23348513.

 

Fanning RA, McMorrow JP, Campion DP, et al. Opioid mediated activity and expression of mu and delta opioid receptors in isolated human term non-labouring myometrium. Eur J Pharmacol. 2013 Jan 5;698(1-3):170-7. PMID: 23051674.

 

Hadjiconstantinou M, Neff NH. Nicotine and endogenous opioids: neurochemical and pharmacological evidence. Neuropharmacology. 2011 Jun;60(7-8):1209-20. PMID: 21108953.

 

Stagg NJ, Mata HP, Ibrahim MM, et al. Regular exercise reverses sensory hypersensitivity in a rat neuropathic pain model: role of endogenous opioids. Anesthesiology. 2011 Apr;114(4):940-8. PMID: 21386701.

 

Gredicak M, Supek F, Kralj M, et al. Computational structure-activity study directs synthesis of novel antitumor enkephalin analogs. Amino Acids. 2010 Apr;38(4):1185-91. PMID: 19639251.

 

Lee HK, Smith MD, Smith BJ, et al. Anticonvulsant Met-enkephalin analogues containing backbone spacers reveal alternative non-opioid signaling in the brain. ACS Chem Biol. 2009 Aug 21;4(8):659-71. PMID: 19634861.

" Not dangerous goods.

LKT E4416 Eledoisin 1 mg 60 Peptide, substance P analog; NK agonist. 69-25-0 ≥95% 1188.44 C54H85N13O15S1 CCC(C)C(C(=O)NCC(=O)NC(CC(C)C)C(=O)NC(CCSC)C(=O)N)NC(=O)C(CC1=CC=CC=C1)NC(=O)C(C)NC(=O)C(CC(=O)O)NC(=O)C(CCCCN)NC(=O)C(CO)NC(=O)C2CCCN2C(=O)C3CCC(=O)N3 Ambient -20°C "Tucci P, Bolle P, Severini C. Effects of natural tachykinins on ovine lower urinary tract smooth muscle. J Auton Pharmacol. 2001 Apr;21(2):79-84. PMID: 11679016.

 

Ito S, Ohta T, Honda H, et al. Gastric vasodilator and motor responses to splanchnic stimulation and tachykinins in the dog. Gen Pharmacol. 1993 Mar;24(2):291-8. PMID: 7683299.

 

Holstein B, Cederberg C. Effects of tachykinins on gastric acid and pepsin secretion and on gastric outflow in the Atlantic cod, Gadus morhua. Am J Physiol. 1986 Mar;250(3 Pt 1):G309-15. PMID: 2420206.

" Not dangerous goods.

LKT E4416 Eledoisin 2 mg 101.9 Peptide, substance P analog; NK agonist. 69-25-0 ≥95% 1188.44 C54H85N13O15S1 CCC(C)C(C(=O)NCC(=O)NC(CC(C)C)C(=O)NC(CCSC)C(=O)N)NC(=O)C(CC1=CC=CC=C1)NC(=O)C(C)NC(=O)C(CC(=O)O)NC(=O)C(CCCCN)NC(=O)C(CO)NC(=O)C2CCCN2C(=O)C3CCC(=O)N3 Ambient -20°C "Tucci P, Bolle P, Severini C. Effects of natural tachykinins on ovine lower urinary tract smooth muscle. J Auton Pharmacol. 2001 Apr;21(2):79-84. PMID: 11679016.

 

Ito S, Ohta T, Honda H, et al. Gastric vasodilator and motor responses to splanchnic stimulation and tachykinins in the dog. Gen Pharmacol. 1993 Mar;24(2):291-8. PMID: 7683299.

 

Holstein B, Cederberg C. Effects of tachykinins on gastric acid and pepsin secretion and on gastric outflow in the Atlantic cod, Gadus morhua. Am J Physiol. 1986 Mar;250(3 Pt 1):G309-15. PMID: 2420206.

" Not dangerous goods.

LKT E4416 Eledoisin 5 mg 180 Peptide, substance P analog; NK agonist. 69-25-0 ≥95% 1188.44 C54H85N13O15S1 CCC(C)C(C(=O)NCC(=O)NC(CC(C)C)C(=O)NC(CCSC)C(=O)N)NC(=O)C(CC1=CC=CC=C1)NC(=O)C(C)NC(=O)C(CC(=O)O)NC(=O)C(CCCCN)NC(=O)C(CO)NC(=O)C2CCCN2C(=O)C3CCC(=O)N3 Ambient -20°C "Tucci P, Bolle P, Severini C. Effects of natural tachykinins on ovine lower urinary tract smooth muscle. J Auton Pharmacol. 2001 Apr;21(2):79-84. PMID: 11679016.

 

Ito S, Ohta T, Honda H, et al. Gastric vasodilator and motor responses to splanchnic stimulation and tachykinins in the dog. Gen Pharmacol. 1993 Mar;24(2):291-8. PMID: 7683299.

 

Holstein B, Cederberg C. Effects of tachykinins on gastric acid and pepsin secretion and on gastric outflow in the Atlantic cod, Gadus morhua. Am J Physiol. 1986 Mar;250(3 Pt 1):G309-15. PMID: 2420206.

" Not dangerous goods.

LKT E4417 Eledoisin Related Peptide 5 mg 120 Peptide, substance P analog; NK agonist. ERP ≥95% 706.96 C34H58N8O6S Ambient -20°C "Clint BD, Lipton JM, Giesecke AH Jr. Analgesic and cardiovascular effects of centrally administered substance P. Peptides. 1988 May-Jun;9(3):619-23. PMID: 2458573.

 

Goel V, Biggs DF. Comparison of the bronchoconstrictor and cardiovascular effects of some tachykinins in guinea pigs. Life Sci. 1987 Mar 9;40(10):1007-15. PMID: 2434817.

 

Holstein B, Cederberg C. Effects of tachykinins on gastric acid and pepsin secretion and on gastric outflow in the Atlantic cod, Gadus morhua. Am J Physiol. 1986 Mar;250(3 Pt 1):G309-15. PMID: 2420206.

" Not dangerous goods.

LKT E4417 Eledoisin Related Peptide 10 mg 204.1 Peptide, substance P analog; NK agonist. ERP ≥95% 706.96 C34H58N8O6S Ambient -20°C "Clint BD, Lipton JM, Giesecke AH Jr. Analgesic and cardiovascular effects of centrally administered substance P. Peptides. 1988 May-Jun;9(3):619-23. PMID: 2458573.

 

Goel V, Biggs DF. Comparison of the bronchoconstrictor and cardiovascular effects of some tachykinins in guinea pigs. Life Sci. 1987 Mar 9;40(10):1007-15. PMID: 2434817.

 

Holstein B, Cederberg C. Effects of tachykinins on gastric acid and pepsin secretion and on gastric outflow in the Atlantic cod, Gadus morhua. Am J Physiol. 1986 Mar;250(3 Pt 1):G309-15. PMID: 2420206.

" Not dangerous goods.

LKT E4417 Eledoisin Related Peptide 25 mg 359.9 Peptide, substance P analog; NK agonist. ERP ≥95% 706.96 C34H58N8O6S Ambient -20°C "Clint BD, Lipton JM, Giesecke AH Jr. Analgesic and cardiovascular effects of centrally administered substance P. Peptides. 1988 May-Jun;9(3):619-23. PMID: 2458573.

 

Goel V, Biggs DF. Comparison of the bronchoconstrictor and cardiovascular effects of some tachykinins in guinea pigs. Life Sci. 1987 Mar 9;40(10):1007-15. PMID: 2434817.

 

Holstein B, Cederberg C. Effects of tachykinins on gastric acid and pepsin secretion and on gastric outflow in the Atlantic cod, Gadus morhua. Am J Physiol. 1986 Mar;250(3 Pt 1):G309-15. PMID: 2420206.

" Not dangerous goods.

LKT E4902 Emamectin B1 Benzoate 100 mg 61.1 Semi-synthetic avermectin; GABA potentiator. MK-244; Affirm; Proclaim. 137512-74-4 ≥80% 886.12 C49H75NO13 CCC(C)C1C(C=CC2(O1)CC3CC(O2)CC=C(C(C(C=CC=C4COC5C4(C(C=C(C5O)C)C(=O)O3)O)C)OC6CC(C(C(O6)C)OC7CC(C(C(O7)C)NC)OC)OC)C)C.C1=CC=C(C=C1)C(=O)O Protect from light. Ambient Ambient Soluble in chloroform or methanol. Yen TH, Lin JL. Acute poisoning with emamectin benzoate. J Toxicol Clin Toxicol. 2004;42(5):657-61. PMID: 15462160. "UN number: 3077     Class: 9     Packing Group: III

Proper shipping name: Environmentally hazardous substance, solid, n.o.s. (Emamectin B1 Benzoate)"

LKT E4902 Emamectin B1 Benzoate 250 mg 101.9 Semi-synthetic avermectin; GABA potentiator. MK-244; Affirm; Proclaim. 137512-74-4 ≥80% 886.12 C49H75NO13 CCC(C)C1C(C=CC2(O1)CC3CC(O2)CC=C(C(C(C=CC=C4COC5C4(C(C=C(C5O)C)C(=O)O3)O)C)OC6CC(C(C(O6)C)OC7CC(C(C(O7)C)NC)OC)OC)C)C.C1=CC=C(C=C1)C(=O)O Protect from light. Ambient Ambient Soluble in chloroform or methanol. Yen TH, Lin JL. Acute poisoning with emamectin benzoate. J Toxicol Clin Toxicol. 2004;42(5):657-61. PMID: 15462160. "UN number: 3077     Class: 9     Packing Group: III

Proper shipping name: Environmentally hazardous substance, solid, n.o.s. (Emamectin B1 Benzoate)"

LKT E4902 Emamectin B1 Benzoate 1 g 271.7 Semi-synthetic avermectin; GABA potentiator. MK-244; Affirm; Proclaim. 137512-74-4 ≥80% 886.12 C49H75NO13 CCC(C)C1C(C=CC2(O1)CC3CC(O2)CC=C(C(C(C=CC=C4COC5C4(C(C=C(C5O)C)C(=O)O3)O)C)OC6CC(C(C(O6)C)OC7CC(C(C(O7)C)NC)OC)OC)C)C.C1=CC=C(C=C1)C(=O)O Protect from light. Ambient Ambient Soluble in chloroform or methanol. Yen TH, Lin JL. Acute poisoning with emamectin benzoate. J Toxicol Clin Toxicol. 2004;42(5):657-61. PMID: 15462160. "UN number: 3077     Class: 9     Packing Group: III

Proper shipping name: Environmentally hazardous substance, solid, n.o.s. (Emamectin B1 Benzoate)"

LKT E5057 Emodin 100 mg 93.8 Anthraquinone found in various plant sources; CTFR Cl- channel activator. 518-82-1 ≥95% 270.24 C15H10O5 CC1=CC(=C2C(=C1)C(=O)C3=CC(=CC(=C3C2=O)O)O)O Ambient Ambient "Ismail S, Haris K, Abdul Ghani AR, et al. Enhanced induction of cell cycle arrest and apoptosis via the mitochondrial membrane potential disruption in human U87 malignant glioma cells by aloe emodin. J Asian Nat Prod Res. 2013 Jul 22. [Epub ahead of print]. PMID: 23869465.

 

Huang PH, Huang CY, Chen MC, et al. Emodin and Aloe-Emodin Suppress Breast Cancer Cell Proliferation through ER α Inhibition. Evid Based Complement Alternat Med. 2013; Epub 2013 Jun 24. PMID: 23864887.

 

Zhang W, Chen H, Liu DL, et al. Emodin sensitizes the gemcitabine-resistant cell line Bxpc-3/Gem to gemcitabine via downregulation of NF-κB and its regulated targets. Int J Oncol. 2013 Apr;42(4):1189-96.  PMID: 23440366.

 

Liu K, Park C, Li S, et al. Aloe-emodin suppresses prostate cancer by targeting the mTOR complex 2. Carcinogenesis. 2012 Jul;33(7):1406-11. PMID: 22532249.

 

Yang H, Xu LN, He CY, et al. CFTR chloride channel as a molecular target of anthraquinone compounds in herbal laxatives. Acta Pharmacol Sin. 2011 Jun;32(6):834-9. PMID: 21602836.

 

Srinivas G, Babykutty S, Sathiadevan PP, et al. Molecular mechanism of emodin action: transition from laxative ingredient to an antitumor agent. Med Res Rev. 2007 Sep;27(5):591-608. PMID: 17019678.

" Xi Not dangerous goods.

LKT E5057 Emodin 250 mg 187.4 Anthraquinone found in various plant sources; CTFR Cl- channel activator. 518-82-1 ≥95% 270.24 C15H10O5 CC1=CC(=C2C(=C1)C(=O)C3=CC(=CC(=C3C2=O)O)O)O Ambient Ambient "Ismail S, Haris K, Abdul Ghani AR, et al. Enhanced induction of cell cycle arrest and apoptosis via the mitochondrial membrane potential disruption in human U87 malignant glioma cells by aloe emodin. J Asian Nat Prod Res. 2013 Jul 22. [Epub ahead of print]. PMID: 23869465.

 

Huang PH, Huang CY, Chen MC, et al. Emodin and Aloe-Emodin Suppress Breast Cancer Cell Proliferation through ER α Inhibition. Evid Based Complement Alternat Med. 2013; Epub 2013 Jun 24. PMID: 23864887.

 

Zhang W, Chen H, Liu DL, et al. Emodin sensitizes the gemcitabine-resistant cell line Bxpc-3/Gem to gemcitabine via downregulation of NF-κB and its regulated targets. Int J Oncol. 2013 Apr;42(4):1189-96.  PMID: 23440366.

 

Liu K, Park C, Li S, et al. Aloe-emodin suppresses prostate cancer by targeting the mTOR complex 2. Carcinogenesis. 2012 Jul;33(7):1406-11. PMID: 22532249.

 

Yang H, Xu LN, He CY, et al. CFTR chloride channel as a molecular target of anthraquinone compounds in herbal laxatives. Acta Pharmacol Sin. 2011 Jun;32(6):834-9. PMID: 21602836.

 

Srinivas G, Babykutty S, Sathiadevan PP, et al. Molecular mechanism of emodin action: transition from laxative ingredient to an antitumor agent. Med Res Rev. 2007 Sep;27(5):591-608. PMID: 17019678.

" Xi Not dangerous goods.

LKT E5057 Emodin 1 g 468.8 Anthraquinone found in various plant sources; CTFR Cl- channel activator. 518-82-1 ≥95% 270.24 C15H10O5 CC1=CC(=C2C(=C1)C(=O)C3=CC(=CC(=C3C2=O)O)O)O Ambient Ambient "Ismail S, Haris K, Abdul Ghani AR, et al. Enhanced induction of cell cycle arrest and apoptosis via the mitochondrial membrane potential disruption in human U87 malignant glioma cells by aloe emodin. J Asian Nat Prod Res. 2013 Jul 22. [Epub ahead of print]. PMID: 23869465.

 

Huang PH, Huang CY, Chen MC, et al. Emodin and Aloe-Emodin Suppress Breast Cancer Cell Proliferation through ER α Inhibition. Evid Based Complement Alternat Med. 2013; Epub 2013 Jun 24. PMID: 23864887.

 

Zhang W, Chen H, Liu DL, et al. Emodin sensitizes the gemcitabine-resistant cell line Bxpc-3/Gem to gemcitabine via downregulation of NF-κB and its regulated targets. Int J Oncol. 2013 Apr;42(4):1189-96.  PMID: 23440366.

 

Liu K, Park C, Li S, et al. Aloe-emodin suppresses prostate cancer by targeting the mTOR complex 2. Carcinogenesis. 2012 Jul;33(7):1406-11. PMID: 22532249.

 

Yang H, Xu LN, He CY, et al. CFTR chloride channel as a molecular target of anthraquinone compounds in herbal laxatives. Acta Pharmacol Sin. 2011 Jun;32(6):834-9. PMID: 21602836.

 

Srinivas G, Babykutty S, Sathiadevan PP, et al. Molecular mechanism of emodin action: transition from laxative ingredient to an antitumor agent. Med Res Rev. 2007 Sep;27(5):591-608. PMID: 17019678.

" Xi Not dangerous goods.

LKT E5200 Enalaprilat Dihydrate 10 mg 114.6 Enalapril metabolite; ACE inhibitor. N-[(1S)-Carboxy- 3-phenylpropyl]-L-alanyl-L-proline dihydrate Enalaprilic acid; Vasotec IV 84680-54-6 ≥98% 384.42 C18H24N2O5 2H2O CC(C(=O)N1CCCC1C(=O)O)NC(CCC2=CC=CC=C2)C(=O)O.O.O Ambient Ambient Slightly soluble in water (14 mg/mL at 60 oC)  DMSO (64 mg/mL), methanol (14 mg/mL). "Chen JL, Shang QH, Hu W, et al. Role of TGF-β1/Smads pathway in carotid artery remodeling in renovascular hypertensive rats and prevention by Enalapril and Amlodipine. J Geriatr Cardiol. 2012 Jun;9(2):185-91. PMID: 22916067.

 

Bilan VP, Salah EM, Bastacky S, et al. Diabetic nephropathy and long-term treatment effects of rosiglitazone and enalapril in obese ZSF1 rats. J Endocrinol. 2011 Sep;210(3):293-308. PMID: 21680617.

 

Javanmard SH, Sonbolestan SA, Heshmat-Ghahdarijani K, et al. Enalapril improves endothelial function in patients with migraine: A randomized, double-blind, placebo-controlled trial. J Res Med Sci. 2011 Jan;16(1):26-32. PMID: 21448379.

" None Not dangerous goods.

LKT E5200 Enalaprilat Dihydrate 50 mg 495.8 Enalapril metabolite; ACE inhibitor. N-[(1S)-Carboxy- 3-phenylpropyl]-L-alanyl-L-proline dihydrate Enalaprilic acid; Vasotec IV 84680-54-6 ≥98% 384.42 C18H24N2O5 2H2O CC(C(=O)N1CCCC1C(=O)O)NC(CCC2=CC=CC=C2)C(=O)O.O.O Ambient Ambient Slightly soluble in water (14 mg/mL at 60 oC)  DMSO (64 mg/mL), methanol (14 mg/mL). "Chen JL, Shang QH, Hu W, et al. Role of TGF-β1/Smads pathway in carotid artery remodeling in renovascular hypertensive rats and prevention by Enalapril and Amlodipine. J Geriatr Cardiol. 2012 Jun;9(2):185-91. PMID: 22916067.

 

Bilan VP, Salah EM, Bastacky S, et al. Diabetic nephropathy and long-term treatment effects of rosiglitazone and enalapril in obese ZSF1 rats. J Endocrinol. 2011 Sep;210(3):293-308. PMID: 21680617.

 

Javanmard SH, Sonbolestan SA, Heshmat-Ghahdarijani K, et al. Enalapril improves endothelial function in patients with migraine: A randomized, double-blind, placebo-controlled trial. J Res Med Sci. 2011 Jan;16(1):26-32. PMID: 21448379.

" None Not dangerous goods.

LKT E5200 Enalaprilat Dihydrate 100 mg 914.9 Enalapril metabolite; ACE inhibitor. N-[(1S)-Carboxy- 3-phenylpropyl]-L-alanyl-L-proline dihydrate Enalaprilic acid; Vasotec IV 84680-54-6 ≥98% 384.42 C18H24N2O5 2H2O CC(C(=O)N1CCCC1C(=O)O)NC(CCC2=CC=CC=C2)C(=O)O.O.O Ambient Ambient Slightly soluble in water (14 mg/mL at 60 oC)  DMSO (64 mg/mL), methanol (14 mg/mL). "Chen JL, Shang QH, Hu W, et al. Role of TGF-β1/Smads pathway in carotid artery remodeling in renovascular hypertensive rats and prevention by Enalapril and Amlodipine. J Geriatr Cardiol. 2012 Jun;9(2):185-91. PMID: 22916067.

 

Bilan VP, Salah EM, Bastacky S, et al. Diabetic nephropathy and long-term treatment effects of rosiglitazone and enalapril in obese ZSF1 rats. J Endocrinol. 2011 Sep;210(3):293-308. PMID: 21680617.

 

Javanmard SH, Sonbolestan SA, Heshmat-Ghahdarijani K, et al. Enalapril improves endothelial function in patients with migraine: A randomized, double-blind, placebo-controlled trial. J Res Med Sci. 2011 Jan;16(1):26-32. PMID: 21448379.

" None Not dangerous goods.

LKT E5201 Enalapril Maleate 1 g 63.8 ACE inhibitor. N-[(1S)-1-(Ethoxycarbonyl)-3-phenylpropyl]-L-alanyl-L-proline maleate Amprace; Bitensil; Cardiovet; Enaloc; Innovace; Lotrial; Naprilene; Pres; Renivace; Xanef 76095-16-4 ≥98% 492.52 C20H28N2O5 C4H4O4 CCOC(=O)C(CCC1=CC=CC=C1)NC(C)C(=O)N2CCCC2C(=O)O.C(=CC(=O)O)C(=O)O Ambient Ambient Sparingly soluble in water and methanol. "Chen JL, Shang QH, Hu W, et al. Role of TGF-β1/Smads pathway in carotid artery remodeling in renovascular hypertensive rats and prevention by Enalapril and Amlodipine. J Geriatr Cardiol. 2012 Jun;9(2):185-91. PMID: 22916067.

 

Bilan VP, Salah EM, Bastacky S, et al. Diabetic nephropathy and long-term treatment effects of rosiglitazone and enalapril in obese ZSF1 rats. J Endocrinol. 2011 Sep;210(3):293-308. PMID: 21680617.

 

Javanmard SH, Sonbolestan SA, Heshmat-Ghahdarijani K, et al. Enalapril improves endothelial function in patients with migraine: A randomized, double-blind, placebo-controlled trial. J Res Med Sci. 2011 Jan;16(1):26-32. PMID: 21448379.

" None Not dangerous goods.

LKT E5201 Enalapril Maleate 5 g 254.3 ACE inhibitor. N-[(1S)-1-(Ethoxycarbonyl)-3-phenylpropyl]-L-alanyl-L-proline maleate Amprace; Bitensil; Cardiovet; Enaloc; Innovace; Lotrial; Naprilene; Pres; Renivace; Xanef 76095-16-4 ≥98% 492.52 C20H28N2O5 C4H4O4 CCOC(=O)C(CCC1=CC=CC=C1)NC(C)C(=O)N2CCCC2C(=O)O.C(=CC(=O)O)C(=O)O Ambient Ambient Sparingly soluble in water and methanol. "Chen JL, Shang QH, Hu W, et al. Role of TGF-β1/Smads pathway in carotid artery remodeling in renovascular hypertensive rats and prevention by Enalapril and Amlodipine. J Geriatr Cardiol. 2012 Jun;9(2):185-91. PMID: 22916067.

 

Bilan VP, Salah EM, Bastacky S, et al. Diabetic nephropathy and long-term treatment effects of rosiglitazone and enalapril in obese ZSF1 rats. J Endocrinol. 2011 Sep;210(3):293-308. PMID: 21680617.

 

Javanmard SH, Sonbolestan SA, Heshmat-Ghahdarijani K, et al. Enalapril improves endothelial function in patients with migraine: A randomized, double-blind, placebo-controlled trial. J Res Med Sci. 2011 Jan;16(1):26-32. PMID: 21448379.

" None Not dangerous goods.

LKT E5202 Enalapril 1 g 57.8 ACE inhibitor. N-[(1S)-1-(Ethoxycarbonyl)-3-phenylpropyl]-L-alanyl-L-proline "RenitecR; VasotecR

 

" 75847-73-3 ≥98% 376.45 C20H28N2O5 CCOC(=O)C(CCC1=CC=CC=C1)NC(C)C(=O)N2CCCC2C(=O)O Ambient -20°C Soluble in water (25mg/L). "Chen JL, Shang QH, Hu W, et al. Role of TGF-β1/Smads pathway in carotid artery remodeling in renovascular hypertensive rats and prevention by Enalapril and Amlodipine. J Geriatr Cardiol. 2012 Jun;9(2):185-91. PMID: 22916067.

 

Bilan VP, Salah EM, Bastacky S, et al. Diabetic nephropathy and long-term treatment effects of rosiglitazone and enalapril in obese ZSF1 rats. J Endocrinol. 2011 Sep;210(3):293-308. PMID: 21680617.

 

Javanmard SH, Sonbolestan SA, Heshmat-Ghahdarijani K, et al. Enalapril improves endothelial function in patients with migraine: A randomized, double-blind, placebo-controlled trial. J Res Med Sci. 2011 Jan;16(1):26-32. PMID: 21448379.

" Not dangerous goods.

LKT E5202 Enalapril 5 g 163.2 ACE inhibitor. N-[(1S)-1-(Ethoxycarbonyl)-3-phenylpropyl]-L-alanyl-L-proline "RenitecR; VasotecR

 

" 75847-73-3 ≥98% 376.45 C20H28N2O5 CCOC(=O)C(CCC1=CC=CC=C1)NC(C)C(=O)N2CCCC2C(=O)O Ambient -20°C Soluble in water (25mg/L). "Chen JL, Shang QH, Hu W, et al. Role of TGF-β1/Smads pathway in carotid artery remodeling in renovascular hypertensive rats and prevention by Enalapril and Amlodipine. J Geriatr Cardiol. 2012 Jun;9(2):185-91. PMID: 22916067.

 

Bilan VP, Salah EM, Bastacky S, et al. Diabetic nephropathy and long-term treatment effects of rosiglitazone and enalapril in obese ZSF1 rats. J Endocrinol. 2011 Sep;210(3):293-308. PMID: 21680617.

 

Javanmard SH, Sonbolestan SA, Heshmat-Ghahdarijani K, et al. Enalapril improves endothelial function in patients with migraine: A randomized, double-blind, placebo-controlled trial. J Res Med Sci. 2011 Jan;16(1):26-32. PMID: 21448379.

" Not dangerous goods.

LKT E5210 Endomorphin-1 5 mg 228 Endogenous opioid peptide; μOr agonist. 189388-22-5 ≥95% 610.72 C34H38N6O5 C1CC(N(C1)C(=O)C(CC2=CC=C(C=C2)O)N)C(=O)NC(CC3=CNC4=CC=CC=C43)C(=O)NC(CC5=CC=CC=C5)C(=O)N Ambient -20°C "Dai X, Song HJ, Cui SG, et al. The stimulative effects of endogenous opioids on endothelial cell proliferation, migration and angiogenesis in vitro. Eur J Pharmacol. 2010 Feb 25;628(1-3):42-50. PMID: 19932695.

 

Anton B, Leff P, Calva JC, et al. Endomorphin 1 and endomorphin 2 suppress in vitro antibody formation at ultra-low concentrations: anti-peptide antibodies but not opioid antagonists block the activity. Brain Behav Immun. 2008 Aug;22(6):824-32. PMID: 18374539.

" Not dangerous goods.

LKT E5210 Endomorphin-1 10 mg 387 Endogenous opioid peptide; μOr agonist. 189388-22-5 ≥95% 610.72 C34H38N6O5 C1CC(N(C1)C(=O)C(CC2=CC=C(C=C2)O)N)C(=O)NC(CC3=CNC4=CC=CC=C43)C(=O)NC(CC5=CC=CC=C5)C(=O)N Ambient -20°C "Dai X, Song HJ, Cui SG, et al. The stimulative effects of endogenous opioids on endothelial cell proliferation, migration and angiogenesis in vitro. Eur J Pharmacol. 2010 Feb 25;628(1-3):42-50. PMID: 19932695.

 

Anton B, Leff P, Calva JC, et al. Endomorphin 1 and endomorphin 2 suppress in vitro antibody formation at ultra-low concentrations: anti-peptide antibodies but not opioid antagonists block the activity. Brain Behav Immun. 2008 Aug;22(6):824-32. PMID: 18374539.

" Not dangerous goods.

LKT E5210 Endomorphin-1 25 mg 684.1 Endogenous opioid peptide; μOr agonist. 189388-22-5 ≥95% 610.72 C34H38N6O5 C1CC(N(C1)C(=O)C(CC2=CC=C(C=C2)O)N)C(=O)NC(CC3=CNC4=CC=CC=C43)C(=O)NC(CC5=CC=CC=C5)C(=O)N Ambient -20°C "Dai X, Song HJ, Cui SG, et al. The stimulative effects of endogenous opioids on endothelial cell proliferation, migration and angiogenesis in vitro. Eur J Pharmacol. 2010 Feb 25;628(1-3):42-50. PMID: 19932695.

 

Anton B, Leff P, Calva JC, et al. Endomorphin 1 and endomorphin 2 suppress in vitro antibody formation at ultra-low concentrations: anti-peptide antibodies but not opioid antagonists block the activity. Brain Behav Immun. 2008 Aug;22(6):824-32. PMID: 18374539.

" Not dangerous goods.

LKT E5211 Endomorphin-2 5 mg 224.5 Endogenous opioid peptide; μOR agonist. 141801-26-5 ≥95% 571.68 C32H37N5O5 C1CC(N(C1)C(=O)C(CC2=CC=C(C=C2)O)N)C(=O)NC(CC3=CC=CC=C3)C(=O)NC(CC4=CC=CC=C4)C(=O)N Ambient -20°C "Liu NJ, Gintzler AR. Spinal endomorphin 2 antinociception and the mechanisms that produce it are both sex- and stage of estrus cycle-dependent in rats. J Pain. 2013 Nov;14(11):1522-30. PMID: 24084000.

 

Dai X, Song HJ, Cui SG, et al. The stimulative effects of endogenous opioids on endothelial cell proliferation, migration and angiogenesis in vitro. Eur J Pharmacol. 2010 Feb 25;628(1-3):42-50. PMID: 19932695.

 

Anton B, Leff P, Calva JC, et al. Endomorphin 1 and endomorphin 2 suppress in vitro antibody formation at ultra-low concentrations: anti-peptide antibodies but not opioid antagonists block the activity. Brain Behav Immun. 2008 Aug;22(6):824-32. PMID: 18374539.

" Not dangerous goods.

LKT E5211 Endomorphin-2 10 mg 387 Endogenous opioid peptide; μOR agonist. 141801-26-5 ≥95% 571.68 C32H37N5O5 C1CC(N(C1)C(=O)C(CC2=CC=C(C=C2)O)N)C(=O)NC(CC3=CC=CC=C3)C(=O)NC(CC4=CC=CC=C4)C(=O)N Ambient -20°C "Liu NJ, Gintzler AR. Spinal endomorphin 2 antinociception and the mechanisms that produce it are both sex- and stage of estrus cycle-dependent in rats. J Pain. 2013 Nov;14(11):1522-30. PMID: 24084000.

 

Dai X, Song HJ, Cui SG, et al. The stimulative effects of endogenous opioids on endothelial cell proliferation, migration and angiogenesis in vitro. Eur J Pharmacol. 2010 Feb 25;628(1-3):42-50. PMID: 19932695.

 

Anton B, Leff P, Calva JC, et al. Endomorphin 1 and endomorphin 2 suppress in vitro antibody formation at ultra-low concentrations: anti-peptide antibodies but not opioid antagonists block the activity. Brain Behav Immun. 2008 Aug;22(6):824-32. PMID: 18374539.

" Not dangerous goods.

LKT E5211 Endomorphin-2 25 mg 684.1 Endogenous opioid peptide; μOR agonist. 141801-26-5 ≥95% 571.68 C32H37N5O5 C1CC(N(C1)C(=O)C(CC2=CC=C(C=C2)O)N)C(=O)NC(CC3=CC=CC=C3)C(=O)NC(CC4=CC=CC=C4)C(=O)N Ambient -20°C "Liu NJ, Gintzler AR. Spinal endomorphin 2 antinociception and the mechanisms that produce it are both sex- and stage of estrus cycle-dependent in rats. J Pain. 2013 Nov;14(11):1522-30. PMID: 24084000.

 

Dai X, Song HJ, Cui SG, et al. The stimulative effects of endogenous opioids on endothelial cell proliferation, migration and angiogenesis in vitro. Eur J Pharmacol. 2010 Feb 25;628(1-3):42-50. PMID: 19932695.

 

Anton B, Leff P, Calva JC, et al. Endomorphin 1 and endomorphin 2 suppress in vitro antibody formation at ultra-low concentrations: anti-peptide antibodies but not opioid antagonists block the activity. Brain Behav Immun. 2008 Aug;22(6):824-32. PMID: 18374539.

" Not dangerous goods.

LKT E5212 Endonuclease Antigenic Site 1 mg 300.1 HIV-1 endonuclease CTL binding pocket fragment. ≥98% 2307.67 C108H167N27O29 Ambient -20°C Rahman MA, Kuse N, Murakoshi H, et al. Raltegravir and elvitegravir-resistance mutation E92Q affects HLA-B*40:02-restricted HIV-1-specific CTL recognition. Microbes Infect. 2014 May;16(5):434-8. PMID: 24657622.

LKT E5212 Endonuclease Antigenic Site 2 mg 510 HIV-1 endonuclease CTL binding pocket fragment. ≥98% 2307.67 C108H167N27O29 Ambient -20°C Rahman MA, Kuse N, Murakoshi H, et al. Raltegravir and elvitegravir-resistance mutation E92Q affects HLA-B*40:02-restricted HIV-1-specific CTL recognition. Microbes Infect. 2014 May;16(5):434-8. PMID: 24657622.

LKT E5212 Endonuclease Antigenic Site 5 mg 900.1 HIV-1 endonuclease CTL binding pocket fragment. ≥98% 2307.67 C108H167N27O29 Ambient -20°C Rahman MA, Kuse N, Murakoshi H, et al. Raltegravir and elvitegravir-resistance mutation E92Q affects HLA-B*40:02-restricted HIV-1-specific CTL recognition. Microbes Infect. 2014 May;16(5):434-8. PMID: 24657622.

LKT E5214 α-Endorphin 1 mg 107.8 Endogenous opioid peptide; μOR agonist. 61512-76-3 ≥95% 1745.98 C77H120N18O26S CC(C)CC(C(=O)NC(C(C)C)C(=O)NC(C(C)O)C(=O)O)NC(=O)C1CCCN1C(=O)C(C(C)O)NC(=O)C(CCC(=O)N)NC(=O)C(CO)NC(=O)C(CCCCN)NC(=O)C(CCC(=O)O)NC(=O)C(CO)NC(=O)C(C(C)O)NC(=O)C(CCSC)NC(=O)C(CC2=CC=CC=C2)NC(=O)CNC(=O)CNC(=O)C(CC3=CC=C(C=C3)O)N Ambient -20°C "Charbogne P, Kieffer BL, Befort K. 15 years of genetic approaches in vivo for addiction research: Opioid receptor and peptide gene knockout in mouse models of drug abuse. Neuropharmacology. 2014 Jan;76 Pt B:204-17. PMID: 24035914.

 

Dinas PC, Koutedakis Y, Flouris AD. Effects of exercise and physical activity on depression. Ir J Med Sci. 2011 Jun;180(2):319-25. PMID: 21076975.

 

Horváth G, Mécs L. Antinociception by endogenous ligands at peripheral level. Ideggyogy Sz. 2011 Mar 30;64(5-6):193-207. PMID: 21688721.

" Not dangerous goods.

LKT E5214 α-Endorphin 2 mg 183 Endogenous opioid peptide; μOR agonist. 61512-76-3 ≥95% 1745.98 C77H120N18O26S CC(C)CC(C(=O)NC(C(C)C)C(=O)NC(C(C)O)C(=O)O)NC(=O)C1CCCN1C(=O)C(C(C)O)NC(=O)C(CCC(=O)N)NC(=O)C(CO)NC(=O)C(CCCCN)NC(=O)C(CCC(=O)O)NC(=O)C(CO)NC(=O)C(C(C)O)NC(=O)C(CCSC)NC(=O)C(CC2=CC=CC=C2)NC(=O)CNC(=O)CNC(=O)C(CC3=CC=C(C=C3)O)N Ambient -20°C "Charbogne P, Kieffer BL, Befort K. 15 years of genetic approaches in vivo for addiction research: Opioid receptor and peptide gene knockout in mouse models of drug abuse. Neuropharmacology. 2014 Jan;76 Pt B:204-17. PMID: 24035914.

 

Dinas PC, Koutedakis Y, Flouris AD. Effects of exercise and physical activity on depression. Ir J Med Sci. 2011 Jun;180(2):319-25. PMID: 21076975.

 

Horváth G, Mécs L. Antinociception by endogenous ligands at peripheral level. Ideggyogy Sz. 2011 Mar 30;64(5-6):193-207. PMID: 21688721.

" Not dangerous goods.

LKT E5214 α-Endorphin 5 mg 324 Endogenous opioid peptide; μOR agonist. 61512-76-3 ≥95% 1745.98 C77H120N18O26S CC(C)CC(C(=O)NC(C(C)C)C(=O)NC(C(C)O)C(=O)O)NC(=O)C1CCCN1C(=O)C(C(C)O)NC(=O)C(CCC(=O)N)NC(=O)C(CO)NC(=O)C(CCCCN)NC(=O)C(CCC(=O)O)NC(=O)C(CO)NC(=O)C(C(C)O)NC(=O)C(CCSC)NC(=O)C(CC2=CC=CC=C2)NC(=O)CNC(=O)CNC(=O)C(CC3=CC=C(C=C3)O)N Ambient -20°C "Charbogne P, Kieffer BL, Befort K. 15 years of genetic approaches in vivo for addiction research: Opioid receptor and peptide gene knockout in mouse models of drug abuse. Neuropharmacology. 2014 Jan;76 Pt B:204-17. PMID: 24035914.

 

Dinas PC, Koutedakis Y, Flouris AD. Effects of exercise and physical activity on depression. Ir J Med Sci. 2011 Jun;180(2):319-25. PMID: 21076975.

 

Horváth G, Mécs L. Antinociception by endogenous ligands at peripheral level. Ideggyogy Sz. 2011 Mar 30;64(5-6):193-207. PMID: 21688721.

" Not dangerous goods.

LKT E5215 Acetyl-α-Endorphin 1 mg 120 Endogenous opioid peptide; μOR agonist. ≥95% 1788.02 C79H122N18O27S Ambient -20°C "Charbogne P, Kieffer BL, Befort K. 15 years of genetic approaches in vivo for addiction research: Opioid receptor and peptide gene knockout in mouse models of drug abuse. Neuropharmacology. 2014 Jan;76 Pt B:204-17. PMID: 24035914.

 

Dinas PC, Koutedakis Y, Flouris AD. Effects of exercise and physical activity on depression. Ir J Med Sci. 2011 Jun;180(2):319-25. PMID: 21076975.

 

Horváth G, Mécs L. Antinociception by endogenous ligands at peripheral level. Ideggyogy Sz. 2011 Mar 30;64(5-6):193-207. PMID: 21688721.

" Not dangerous goods.

LKT E5215 Acetyl-α-Endorphin 2 mg 204.1 Endogenous opioid peptide; μOR agonist. ≥95% 1788.02 C79H122N18O27S Ambient -20°C "Charbogne P, Kieffer BL, Befort K. 15 years of genetic approaches in vivo for addiction research: Opioid receptor and peptide gene knockout in mouse models of drug abuse. Neuropharmacology. 2014 Jan;76 Pt B:204-17. PMID: 24035914.

 

Dinas PC, Koutedakis Y, Flouris AD. Effects of exercise and physical activity on depression. Ir J Med Sci. 2011 Jun;180(2):319-25. PMID: 21076975.

 

Horváth G, Mécs L. Antinociception by endogenous ligands at peripheral level. Ideggyogy Sz. 2011 Mar 30;64(5-6):193-207. PMID: 21688721.

" Not dangerous goods.

LKT E5215 Acetyl-α-Endorphin 5 mg 359.9 Endogenous opioid peptide; μOR agonist. ≥95% 1788.02 C79H122N18O27S Ambient -20°C "Charbogne P, Kieffer BL, Befort K. 15 years of genetic approaches in vivo for addiction research: Opioid receptor and peptide gene knockout in mouse models of drug abuse. Neuropharmacology. 2014 Jan;76 Pt B:204-17. PMID: 24035914.

 

Dinas PC, Koutedakis Y, Flouris AD. Effects of exercise and physical activity on depression. Ir J Med Sci. 2011 Jun;180(2):319-25. PMID: 21076975.

 

Horváth G, Mécs L. Antinociception by endogenous ligands at peripheral level. Ideggyogy Sz. 2011 Mar 30;64(5-6):193-207. PMID: 21688721.

" Not dangerous goods.

LKT E5216 β-Endorphin, camel 1 mg 276.2 Endogenous opioid peptide; μOR agonist. ≥95% 3438.04 C155H250N42O44S Ambient -20°C "Charbogne P, Kieffer BL, Befort K. 15 years of genetic approaches in vivo for addiction research: Opioid receptor and peptide gene knockout in mouse models of drug abuse. Neuropharmacology. 2014 Jan;76 Pt B:204-17. PMID: 24035914.

 

Gein SV, Baeva TA, Nebogatikov VO, et al. β-Endorphin effects on antibody production, proliferation, and secretion of Th1/Th2 cytokines in vivo. Bull Exp Biol Med. 2012 Mar;152(5):595-9. PMID: 22803142.

 

Dinas PC, Koutedakis Y, Flouris AD. Effects of exercise and physical activity on depression. Ir J Med Sci. 2011 Jun;180(2):319-25. PMID: 21076975.

 

Horváth G, Mécs L. Antinociception by endogenous ligands at peripheral level. Ideggyogy Sz. 2011 Mar 30;64(5-6):193-207. PMID: 21688721.

" Not dangerous goods.

LKT E5216 β-Endorphin, camel 2 mg 468.2 Endogenous opioid peptide; μOR agonist. ≥95% 3438.04 C155H250N42O44S Ambient -20°C "Charbogne P, Kieffer BL, Befort K. 15 years of genetic approaches in vivo for addiction research: Opioid receptor and peptide gene knockout in mouse models of drug abuse. Neuropharmacology. 2014 Jan;76 Pt B:204-17. PMID: 24035914.

 

Gein SV, Baeva TA, Nebogatikov VO, et al. β-Endorphin effects on antibody production, proliferation, and secretion of Th1/Th2 cytokines in vivo. Bull Exp Biol Med. 2012 Mar;152(5):595-9. PMID: 22803142.

 

Dinas PC, Koutedakis Y, Flouris AD. Effects of exercise and physical activity on depression. Ir J Med Sci. 2011 Jun;180(2):319-25. PMID: 21076975.

 

Horváth G, Mécs L. Antinociception by endogenous ligands at peripheral level. Ideggyogy Sz. 2011 Mar 30;64(5-6):193-207. PMID: 21688721.

" Not dangerous goods.

LKT E5216 β-Endorphin, camel 5 mg 828.1 Endogenous opioid peptide; μOR agonist. ≥95% 3438.04 C155H250N42O44S Ambient -20°C "Charbogne P, Kieffer BL, Befort K. 15 years of genetic approaches in vivo for addiction research: Opioid receptor and peptide gene knockout in mouse models of drug abuse. Neuropharmacology. 2014 Jan;76 Pt B:204-17. PMID: 24035914.

 

Gein SV, Baeva TA, Nebogatikov VO, et al. β-Endorphin effects on antibody production, proliferation, and secretion of Th1/Th2 cytokines in vivo. Bull Exp Biol Med. 2012 Mar;152(5):595-9. PMID: 22803142.

 

Dinas PC, Koutedakis Y, Flouris AD. Effects of exercise and physical activity on depression. Ir J Med Sci. 2011 Jun;180(2):319-25. PMID: 21076975.

 

Horváth G, Mécs L. Antinociception by endogenous ligands at peripheral level. Ideggyogy Sz. 2011 Mar 30;64(5-6):193-207. PMID: 21688721.

" Not dangerous goods.

LKT E5217 β-Endorphin, human 1 mg 180 Endogenous opioid peptide; μOR agonist. ≥95% 3465.06 C158H251N39O46S CCC(C)C(C(=O)NC(C(C)CC)C(=O)NC(CCCCN)C(=O)NC(CC(=O)N)C(=O)NC(C)C(=O)NC(CC1=CC=C(C=C1)O)C(=O)NC(CCCCN)C(=O)NC(CCCCN)C(=O)NCC(=O)NC(CCC(=O)O)C(=O)O)NC(=O)C(C)NC(=O)C(CC(=O)N)NC(=O)C(CCCCN)NC(=O)C(CC2=CC=CC=C2)NC(=O)C(CC(C)C)NC(=O)C(C(C)O)NC(=O)C(C(C)C)NC(=O)C(CC(C)C)NC(=O)C3CCCN3C(=O)C(C(C)O)NC(=O)C(CCC(=O)N)NC(=O)C(CO)NC(=O)C(CCCCN)NC(=O)C(CCC(=O)O)NC(=O)C(CO)NC(=O)C(C(C)O)NC(=O)C(CCSC)NC(=O)C(CC4=CC=CC=C4)NC(=O)CNC(=O)CNC(=O)C(CC5=CC=C(C=C5)O)N Ambient -20°C "Charbogne P, Kieffer BL, Befort K. 15 years of genetic approaches in vivo for addiction research: Opioid receptor and peptide gene knockout in mouse models of drug abuse. Neuropharmacology. 2014 Jan;76 Pt B:204-17. PMID: 24035914.

 

Gein SV, Baeva TA, Nebogatikov VO, et al. β-Endorphin effects on antibody production, proliferation, and secretion of Th1/Th2 cytokines in vivo. Bull Exp Biol Med. 2012 Mar;152(5):595-9. PMID: 22803142.

 

Dinas PC, Koutedakis Y, Flouris AD. Effects of exercise and physical activity on depression. Ir J Med Sci. 2011 Jun;180(2):319-25. PMID: 21076975.

 

Horváth G, Mécs L. Antinociception by endogenous ligands at peripheral level. Ideggyogy Sz. 2011 Mar 30;64(5-6):193-207. PMID: 21688721.

" Not dangerous goods.

LKT E5217 β-Endorphin, human 2 mg 306.1 Endogenous opioid peptide; μOR agonist. ≥95% 3465.06 C158H251N39O46S CCC(C)C(C(=O)NC(C(C)CC)C(=O)NC(CCCCN)C(=O)NC(CC(=O)N)C(=O)NC(C)C(=O)NC(CC1=CC=C(C=C1)O)C(=O)NC(CCCCN)C(=O)NC(CCCCN)C(=O)NCC(=O)NC(CCC(=O)O)C(=O)O)NC(=O)C(C)NC(=O)C(CC(=O)N)NC(=O)C(CCCCN)NC(=O)C(CC2=CC=CC=C2)NC(=O)C(CC(C)C)NC(=O)C(C(C)O)NC(=O)C(C(C)C)NC(=O)C(CC(C)C)NC(=O)C3CCCN3C(=O)C(C(C)O)NC(=O)C(CCC(=O)N)NC(=O)C(CO)NC(=O)C(CCCCN)NC(=O)C(CCC(=O)O)NC(=O)C(CO)NC(=O)C(C(C)O)NC(=O)C(CCSC)NC(=O)C(CC4=CC=CC=C4)NC(=O)CNC(=O)CNC(=O)C(CC5=CC=C(C=C5)O)N Ambient -20°C "Charbogne P, Kieffer BL, Befort K. 15 years of genetic approaches in vivo for addiction research: Opioid receptor and peptide gene knockout in mouse models of drug abuse. Neuropharmacology. 2014 Jan;76 Pt B:204-17. PMID: 24035914.

 

Gein SV, Baeva TA, Nebogatikov VO, et al. β-Endorphin effects on antibody production, proliferation, and secretion of Th1/Th2 cytokines in vivo. Bull Exp Biol Med. 2012 Mar;152(5):595-9. PMID: 22803142.

 

Dinas PC, Koutedakis Y, Flouris AD. Effects of exercise and physical activity on depression. Ir J Med Sci. 2011 Jun;180(2):319-25. PMID: 21076975.

 

Horváth G, Mécs L. Antinociception by endogenous ligands at peripheral level. Ideggyogy Sz. 2011 Mar 30;64(5-6):193-207. PMID: 21688721.

" Not dangerous goods.

LKT E5217 β-Endorphin, human 5 mg 540 Endogenous opioid peptide; μOR agonist. ≥95% 3465.06 C158H251N39O46S CCC(C)C(C(=O)NC(C(C)CC)C(=O)NC(CCCCN)C(=O)NC(CC(=O)N)C(=O)NC(C)C(=O)NC(CC1=CC=C(C=C1)O)C(=O)NC(CCCCN)C(=O)NC(CCCCN)C(=O)NCC(=O)NC(CCC(=O)O)C(=O)O)NC(=O)C(C)NC(=O)C(CC(=O)N)NC(=O)C(CCCCN)NC(=O)C(CC2=CC=CC=C2)NC(=O)C(CC(C)C)NC(=O)C(C(C)O)NC(=O)C(C(C)C)NC(=O)C(CC(C)C)NC(=O)C3CCCN3C(=O)C(C(C)O)NC(=O)C(CCC(=O)N)NC(=O)C(CO)NC(=O)C(CCCCN)NC(=O)C(CCC(=O)O)NC(=O)C(CO)NC(=O)C(C(C)O)NC(=O)C(CCSC)NC(=O)C(CC4=CC=CC=C4)NC(=O)CNC(=O)CNC(=O)C(CC5=CC=C(C=C5)O)N Ambient -20°C "Charbogne P, Kieffer BL, Befort K. 15 years of genetic approaches in vivo for addiction research: Opioid receptor and peptide gene knockout in mouse models of drug abuse. Neuropharmacology. 2014 Jan;76 Pt B:204-17. PMID: 24035914.

 

Gein SV, Baeva TA, Nebogatikov VO, et al. β-Endorphin effects on antibody production, proliferation, and secretion of Th1/Th2 cytokines in vivo. Bull Exp Biol Med. 2012 Mar;152(5):595-9. PMID: 22803142.

 

Dinas PC, Koutedakis Y, Flouris AD. Effects of exercise and physical activity on depression. Ir J Med Sci. 2011 Jun;180(2):319-25. PMID: 21076975.

 

Horváth G, Mécs L. Antinociception by endogenous ligands at peripheral level. Ideggyogy Sz. 2011 Mar 30;64(5-6):193-207. PMID: 21688721.

" Not dangerous goods.

LKT E5218 β-Endorphin, rat 1 mg 300.1 Endogenous opioid peptide; μOR agonist. ≥95% 3466.09 C157H254N42O44S Ambient -20°C "Charbogne P, Kieffer BL, Befort K. 15 years of genetic approaches in vivo for addiction research: Opioid receptor and peptide gene knockout in mouse models of drug abuse. Neuropharmacology. 2014 Jan;76 Pt B:204-17. PMID: 24035914.

 

Gein SV, Baeva TA, Nebogatikov VO, et al. β-Endorphin effects on antibody production, proliferation, and secretion of Th1/Th2 cytokines in vivo. Bull Exp Biol Med. 2012 Mar;152(5):595-9. PMID: 22803142.

 

Dinas PC, Koutedakis Y, Flouris AD. Effects of exercise and physical activity on depression. Ir J Med Sci. 2011 Jun;180(2):319-25. PMID: 21076975.

 

Horváth G, Mécs L. Antinociception by endogenous ligands at peripheral level. Ideggyogy Sz. 2011 Mar 30;64(5-6):193-207. PMID: 21688721.

" Not dangerous goods.

LKT E5218 β-Endorphin, rat 2 mg 510 Endogenous opioid peptide; μOR agonist. ≥95% 3466.09 C157H254N42O44S Ambient -20°C "Charbogne P, Kieffer BL, Befort K. 15 years of genetic approaches in vivo for addiction research: Opioid receptor and peptide gene knockout in mouse models of drug abuse. Neuropharmacology. 2014 Jan;76 Pt B:204-17. PMID: 24035914.

 

Gein SV, Baeva TA, Nebogatikov VO, et al. β-Endorphin effects on antibody production, proliferation, and secretion of Th1/Th2 cytokines in vivo. Bull Exp Biol Med. 2012 Mar;152(5):595-9. PMID: 22803142.

 

Dinas PC, Koutedakis Y, Flouris AD. Effects of exercise and physical activity on depression. Ir J Med Sci. 2011 Jun;180(2):319-25. PMID: 21076975.

 

Horváth G, Mécs L. Antinociception by endogenous ligands at peripheral level. Ideggyogy Sz. 2011 Mar 30;64(5-6):193-207. PMID: 21688721.

" Not dangerous goods.

LKT E5218 β-Endorphin, rat 5 mg 900.1 Endogenous opioid peptide; μOR agonist. ≥95% 3466.09 C157H254N42O44S Ambient -20°C "Charbogne P, Kieffer BL, Befort K. 15 years of genetic approaches in vivo for addiction research: Opioid receptor and peptide gene knockout in mouse models of drug abuse. Neuropharmacology. 2014 Jan;76 Pt B:204-17. PMID: 24035914.

 

Gein SV, Baeva TA, Nebogatikov VO, et al. β-Endorphin effects on antibody production, proliferation, and secretion of Th1/Th2 cytokines in vivo. Bull Exp Biol Med. 2012 Mar;152(5):595-9. PMID: 22803142.

 

Dinas PC, Koutedakis Y, Flouris AD. Effects of exercise and physical activity on depression. Ir J Med Sci. 2011 Jun;180(2):319-25. PMID: 21076975.

 

Horváth G, Mécs L. Antinociception by endogenous ligands at peripheral level. Ideggyogy Sz. 2011 Mar 30;64(5-6):193-207. PMID: 21688721.

" Not dangerous goods.

LKT E5219 Endothelin-1, human 0.5 mg 600.1 Endogenous peptide involved in vascular contraction. ET-A/B agonist. ≥95% 2491.95 C109H159N25O32S5 CCC(C)C(C(=O)NC(C(C)CC)C(=O)NC(CC1=CNC2=CC=CC=C21)C(=O)O)NC(=O)C(CC(=O)O)NC(=O)C(CC(C)C)NC(=O)C(CC3=CN=CN3)NC(=O)C4CSSCC(C(=O)NC(C(=O)NC5CSSCC(C(=O)NC(C(=O)NC(C(=O)NC(C(=O)N4)CC6=CC=CC=C6)CC7=CC=C(C=C7)O)C(C)C)NC(=O)C(NC(=O)C(NC(=O)C(NC(=O)C(NC(=O)C(NC(=O)C(NC(=O)C(NC5=O)CO)CO)CC(C)C)CCSC)CC(=O)O)CCCCN)CCC(=O)O)CO)N Ambient -20°C "Zhong X, Wang H, Huang S. Endothelin-1 induces interleukin-18 expression in human osteoblasts. Arch Oral Biol. 2014 Mar;59(3):289-96. PMID: 24581851.

 

Osmond JM, Gonzalez Bosc LV, Walker BR, et al. Endothelin-1-induced vasoconstriction does not require intracellular Ca2+ waves in arteries from rats exposed to intermittent hypoxia. Am J Physiol Heart Circ Physiol. 2014 Mar;306(5):H667-73. PMID: 24414066.

 

Wolf D, Tseng N, Seedorf G, et al. Endothelin-1 decreases endothelial PPARγ signaling and impairs angiogenesis after chronic intrauterine pulmonary hypertension. Am J Physiol Lung Cell Mol Physiol. 2014 Feb;306(4):L361-71. PMID: 24337925.

" Not dangerous goods.

LKT E5219 Endothelin-1, human 1 mg 1020.2 Endogenous peptide involved in vascular contraction. ET-A/B agonist. ≥95% 2491.95 C109H159N25O32S5 CCC(C)C(C(=O)NC(C(C)CC)C(=O)NC(CC1=CNC2=CC=CC=C21)C(=O)O)NC(=O)C(CC(=O)O)NC(=O)C(CC(C)C)NC(=O)C(CC3=CN=CN3)NC(=O)C4CSSCC(C(=O)NC(C(=O)NC5CSSCC(C(=O)NC(C(=O)NC(C(=O)NC(C(=O)N4)CC6=CC=CC=C6)CC7=CC=C(C=C7)O)C(C)C)NC(=O)C(NC(=O)C(NC(=O)C(NC(=O)C(NC(=O)C(NC(=O)C(NC(=O)C(NC5=O)CO)CO)CC(C)C)CCSC)CC(=O)O)CCCCN)CCC(=O)O)CO)N Ambient -20°C "Zhong X, Wang H, Huang S. Endothelin-1 induces interleukin-18 expression in human osteoblasts. Arch Oral Biol. 2014 Mar;59(3):289-96. PMID: 24581851.

 

Osmond JM, Gonzalez Bosc LV, Walker BR, et al. Endothelin-1-induced vasoconstriction does not require intracellular Ca2+ waves in arteries from rats exposed to intermittent hypoxia. Am J Physiol Heart Circ Physiol. 2014 Mar;306(5):H667-73. PMID: 24414066.

 

Wolf D, Tseng N, Seedorf G, et al. Endothelin-1 decreases endothelial PPARγ signaling and impairs angiogenesis after chronic intrauterine pulmonary hypertension. Am J Physiol Lung Cell Mol Physiol. 2014 Feb;306(4):L361-71. PMID: 24337925.

" Not dangerous goods.

LKT E5219 Endothelin-1, human 2.5 mg 1800.2 Endogenous peptide involved in vascular contraction. ET-A/B agonist. ≥95% 2491.95 C109H159N25O32S5 CCC(C)C(C(=O)NC(C(C)CC)C(=O)NC(CC1=CNC2=CC=CC=C21)C(=O)O)NC(=O)C(CC(=O)O)NC(=O)C(CC(C)C)NC(=O)C(CC3=CN=CN3)NC(=O)C4CSSCC(C(=O)NC(C(=O)NC5CSSCC(C(=O)NC(C(=O)NC(C(=O)NC(C(=O)N4)CC6=CC=CC=C6)CC7=CC=C(C=C7)O)C(C)C)NC(=O)C(NC(=O)C(NC(=O)C(NC(=O)C(NC(=O)C(NC(=O)C(NC(=O)C(NC5=O)CO)CO)CC(C)C)CCSC)CC(=O)O)CCCCN)CCC(=O)O)CO)N Ambient -20°C "Zhong X, Wang H, Huang S. Endothelin-1 induces interleukin-18 expression in human osteoblasts. Arch Oral Biol. 2014 Mar;59(3):289-96. PMID: 24581851.

 

Osmond JM, Gonzalez Bosc LV, Walker BR, et al. Endothelin-1-induced vasoconstriction does not require intracellular Ca2+ waves in arteries from rats exposed to intermittent hypoxia. Am J Physiol Heart Circ Physiol. 2014 Mar;306(5):H667-73. PMID: 24414066.

 

Wolf D, Tseng N, Seedorf G, et al. Endothelin-1 decreases endothelial PPARγ signaling and impairs angiogenesis after chronic intrauterine pulmonary hypertension. Am J Physiol Lung Cell Mol Physiol. 2014 Feb;306(4):L361-71. PMID: 24337925.

" Not dangerous goods.

LKT E5220 Enfuvirtide (T-20) 1 mg 300.1 Synthetic peptide derived from HIV-1; viral fusion inhibitor. T20; Fuzeon; Pentafuside; DP178. 159519-65-0 ≥95% 4462 C204H301N51O64 CCC(C)C(C(=O)NC(CCC(=O)O)C(=O)NC(CCC(=O)O)C(=O)NC(CO)C(=O)NC(CCC(=O)N)C(=O)NC(CC(=O)N)C(=O)NC(CCC(=O)N)C(=O)NC(CCC(=O)N)C(=O)NC(CCC(=O)O)C(=O)NC(CCCCN)C(=O)NC(CC(=O)N)C(=O)NC(CCC(=O)O)C(=O)NC(CCC(=O)N)C(=O)NC(CCC(=O)O)C(=O)NC(CC(C)C)C(=O)NC(CC(C)C)C(=O)NC(CCC(=O)O)C(=O)NC(CC(C)C)C(=O)NC(CC(=O)O)C(=O)NC(CCCCN)C(=O)NC(CC1=CNC2=CC=CC=C21)C(=O)NC(C)C(=O)NC(CO)C(=O)NC(CC(C)C)C(=O)NC(CC3=CNC4=CC=CC=C43)C(=O)NC(CC(=O)N)C(=O)NC(CC5=CNC6=CC=CC=C65)C(=O)NC(CC7=CC=CC=C7)C(=O)N)NC(=O)C(CC(C)C)NC(=O)C(CO)NC(=O)C(CC8=CN=CN8)NC(=O)C(C(C)CC)NC(=O)C(CC(C)C)NC(=O)C(CO)NC(=O)C(C(C)O)NC(=O)C(CC9=CC=C(C=C9)O)NC(=O)C Ambient -20°C Enfuvirtide lyophilized powder is best dissolved in alkaline conditions such as sterile pyrogen free 0.1% NaOH, 1% Na2CO3 or disodium phenyl phosphate at a concentration of 0.1mg/ml-1mg/ml. Enfuvirtide is insoluble in water. "Tan JJ, Ma XT, Liu C, et al. The current status and challenges in the development of fusion inhibitors as therapeutics for HIV-1 infection. Curr Pharm Des. 2013;19(10):1810-7. PMID: 23092283.

 

Cai L, Gochin M, Liu K. Biochemistry and biophysics of HIV-1 gp41 - membrane interactions and implications for HIV-1 envelope protein mediated viral-cell fusion and fusion inhibitor design. Curr Top Med Chem. 2011 Dec;11(24):2959-84. PMID: 22044229.

" Not dangerous goods.

LKT E5220 Enfuvirtide (T-20) 2 mg 510 Synthetic peptide derived from HIV-1; viral fusion inhibitor. T20; Fuzeon; Pentafuside; DP178. 159519-65-0 ≥95% 4462 C204H301N51O64 CCC(C)C(C(=O)NC(CCC(=O)O)C(=O)NC(CCC(=O)O)C(=O)NC(CO)C(=O)NC(CCC(=O)N)C(=O)NC(CC(=O)N)C(=O)NC(CCC(=O)N)C(=O)NC(CCC(=O)N)C(=O)NC(CCC(=O)O)C(=O)NC(CCCCN)C(=O)NC(CC(=O)N)C(=O)NC(CCC(=O)O)C(=O)NC(CCC(=O)N)C(=O)NC(CCC(=O)O)C(=O)NC(CC(C)C)C(=O)NC(CC(C)C)C(=O)NC(CCC(=O)O)C(=O)NC(CC(C)C)C(=O)NC(CC(=O)O)C(=O)NC(CCCCN)C(=O)NC(CC1=CNC2=CC=CC=C21)C(=O)NC(C)C(=O)NC(CO)C(=O)NC(CC(C)C)C(=O)NC(CC3=CNC4=CC=CC=C43)C(=O)NC(CC(=O)N)C(=O)NC(CC5=CNC6=CC=CC=C65)C(=O)NC(CC7=CC=CC=C7)C(=O)N)NC(=O)C(CC(C)C)NC(=O)C(CO)NC(=O)C(CC8=CN=CN8)NC(=O)C(C(C)CC)NC(=O)C(CC(C)C)NC(=O)C(CO)NC(=O)C(C(C)O)NC(=O)C(CC9=CC=C(C=C9)O)NC(=O)C Ambient -20°C Enfuvirtide lyophilized powder is best dissolved in alkaline conditions such as sterile pyrogen free 0.1% NaOH, 1% Na2CO3 or disodium phenyl phosphate at a concentration of 0.1mg/ml-1mg/ml. Enfuvirtide is insoluble in water. "Tan JJ, Ma XT, Liu C, et al. The current status and challenges in the development of fusion inhibitors as therapeutics for HIV-1 infection. Curr Pharm Des. 2013;19(10):1810-7. PMID: 23092283.

 

Cai L, Gochin M, Liu K. Biochemistry and biophysics of HIV-1 gp41 - membrane interactions and implications for HIV-1 envelope protein mediated viral-cell fusion and fusion inhibitor design. Curr Top Med Chem. 2011 Dec;11(24):2959-84. PMID: 22044229.

" Not dangerous goods.

LKT E5220 Enfuvirtide (T-20) 5 mg 900.1 Synthetic peptide derived from HIV-1; viral fusion inhibitor. T20; Fuzeon; Pentafuside; DP178. 159519-65-0 ≥95% 4462 C204H301N51O64 CCC(C)C(C(=O)NC(CCC(=O)O)C(=O)NC(CCC(=O)O)C(=O)NC(CO)C(=O)NC(CCC(=O)N)C(=O)NC(CC(=O)N)C(=O)NC(CCC(=O)N)C(=O)NC(CCC(=O)N)C(=O)NC(CCC(=O)O)C(=O)NC(CCCCN)C(=O)NC(CC(=O)N)C(=O)NC(CCC(=O)O)C(=O)NC(CCC(=O)N)C(=O)NC(CCC(=O)O)C(=O)NC(CC(C)C)C(=O)NC(CC(C)C)C(=O)NC(CCC(=O)O)C(=O)NC(CC(C)C)C(=O)NC(CC(=O)O)C(=O)NC(CCCCN)C(=O)NC(CC1=CNC2=CC=CC=C21)C(=O)NC(C)C(=O)NC(CO)C(=O)NC(CC(C)C)C(=O)NC(CC3=CNC4=CC=CC=C43)C(=O)NC(CC(=O)N)C(=O)NC(CC5=CNC6=CC=CC=C65)C(=O)NC(CC7=CC=CC=C7)C(=O)N)NC(=O)C(CC(C)C)NC(=O)C(CO)NC(=O)C(CC8=CN=CN8)NC(=O)C(C(C)CC)NC(=O)C(CC(C)C)NC(=O)C(CO)NC(=O)C(C(C)O)NC(=O)C(CC9=CC=C(C=C9)O)NC(=O)C Ambient -20°C Enfuvirtide lyophilized powder is best dissolved in alkaline conditions such as sterile pyrogen free 0.1% NaOH, 1% Na2CO3 or disodium phenyl phosphate at a concentration of 0.1mg/ml-1mg/ml. Enfuvirtide is insoluble in water. "Tan JJ, Ma XT, Liu C, et al. The current status and challenges in the development of fusion inhibitors as therapeutics for HIV-1 infection. Curr Pharm Des. 2013;19(10):1810-7. PMID: 23092283.

 

Cai L, Gochin M, Liu K. Biochemistry and biophysics of HIV-1 gp41 - membrane interactions and implications for HIV-1 envelope protein mediated viral-cell fusion and fusion inhibitor design. Curr Top Med Chem. 2011 Dec;11(24):2959-84. PMID: 22044229.

" Not dangerous goods.

LKT E5221 Endothelin-2, human 0.5 mg 600.1 Endogenous peptide involved in vascular contraction. ET-A/B agonist. 123562-20-9 ≥95% 2546.97 C115H160N26O32S4 CCC(C)C(C(=O)NC(C(C)CC)C(=O)NC(CC1=CNC2=CC=CC=C21)C(=O)O)NC(=O)C(CC(=O)O)NC(=O)C(CC(C)C)NC(=O)C(CC3=CN=CN3)NC(=O)C4CSSCC(C(=O)NC(C(=O)NC5CSSCC(C(=O)NC(C(=O)NC(C(=O)NC(C(=O)N4)CC6=CC=CC=C6)CC7=CC=C(C=C7)O)C(C)C)NC(=O)C(NC(=O)C(NC(=O)C(NC(=O)C(NC(=O)C(NC(=O)C(NC(=O)C(NC5=O)CO)CO)CC8=CNC9=CC=CC=C98)CC(C)C)CC(=O)O)CCCCN)CCC(=O)O)CO)N Ambient -20°C "Compeer MG, Janssen GM, De Mey JG. Endothelin-1 and endothelin-2 initiate and maintain contractile responses by different mechanisms in rat mesenteric and cerebral arteries. Br J Pharmacol. 2013 Nov;170(6):1199-209. PMID: 23941276.

 

Rattner A, Yu H, Williams J, et al. Endothelin-2 signaling in the neural retina promotes the endothelial tip cell state and inhibits angiogenesis. Proc Natl Acad Sci U S A. 2013 Oct 1;110(40):E3830-9. PMID: 24043815.

 

Yuen TJ, Johnson KR, Miron VE, et al. Identification of endothelin 2 as an inflammatory factor that promotes central nervous system remyelination. Brain. 2013 Apr;136(Pt 4):1035-47. PMID: 23518706.

" T+ Not dangerous goods.

LKT E5221 Endothelin-2, human 1 mg 1020.2 Endogenous peptide involved in vascular contraction. ET-A/B agonist. 123562-20-9 ≥95% 2546.97 C115H160N26O32S4 CCC(C)C(C(=O)NC(C(C)CC)C(=O)NC(CC1=CNC2=CC=CC=C21)C(=O)O)NC(=O)C(CC(=O)O)NC(=O)C(CC(C)C)NC(=O)C(CC3=CN=CN3)NC(=O)C4CSSCC(C(=O)NC(C(=O)NC5CSSCC(C(=O)NC(C(=O)NC(C(=O)NC(C(=O)N4)CC6=CC=CC=C6)CC7=CC=C(C=C7)O)C(C)C)NC(=O)C(NC(=O)C(NC(=O)C(NC(=O)C(NC(=O)C(NC(=O)C(NC(=O)C(NC5=O)CO)CO)CC8=CNC9=CC=CC=C98)CC(C)C)CC(=O)O)CCCCN)CCC(=O)O)CO)N Ambient -20°C "Compeer MG, Janssen GM, De Mey JG. Endothelin-1 and endothelin-2 initiate and maintain contractile responses by different mechanisms in rat mesenteric and cerebral arteries. Br J Pharmacol. 2013 Nov;170(6):1199-209. PMID: 23941276.

 

Rattner A, Yu H, Williams J, et al. Endothelin-2 signaling in the neural retina promotes the endothelial tip cell state and inhibits angiogenesis. Proc Natl Acad Sci U S A. 2013 Oct 1;110(40):E3830-9. PMID: 24043815.

 

Yuen TJ, Johnson KR, Miron VE, et al. Identification of endothelin 2 as an inflammatory factor that promotes central nervous system remyelination. Brain. 2013 Apr;136(Pt 4):1035-47. PMID: 23518706.

" T+ Not dangerous goods.

LKT E5221 Endothelin-2, human 2.5 mg 1800.2 Endogenous peptide involved in vascular contraction. ET-A/B agonist. 123562-20-9 ≥95% 2546.97 C115H160N26O32S4 CCC(C)C(C(=O)NC(C(C)CC)C(=O)NC(CC1=CNC2=CC=CC=C21)C(=O)O)NC(=O)C(CC(=O)O)NC(=O)C(CC(C)C)NC(=O)C(CC3=CN=CN3)NC(=O)C4CSSCC(C(=O)NC(C(=O)NC5CSSCC(C(=O)NC(C(=O)NC(C(=O)NC(C(=O)N4)CC6=CC=CC=C6)CC7=CC=C(C=C7)O)C(C)C)NC(=O)C(NC(=O)C(NC(=O)C(NC(=O)C(NC(=O)C(NC(=O)C(NC(=O)C(NC5=O)CO)CO)CC8=CNC9=CC=CC=C98)CC(C)C)CC(=O)O)CCCCN)CCC(=O)O)CO)N Ambient -20°C "Compeer MG, Janssen GM, De Mey JG. Endothelin-1 and endothelin-2 initiate and maintain contractile responses by different mechanisms in rat mesenteric and cerebral arteries. Br J Pharmacol. 2013 Nov;170(6):1199-209. PMID: 23941276.

 

Rattner A, Yu H, Williams J, et al. Endothelin-2 signaling in the neural retina promotes the endothelial tip cell state and inhibits angiogenesis. Proc Natl Acad Sci U S A. 2013 Oct 1;110(40):E3830-9. PMID: 24043815.

 

Yuen TJ, Johnson KR, Miron VE, et al. Identification of endothelin 2 as an inflammatory factor that promotes central nervous system remyelination. Brain. 2013 Apr;136(Pt 4):1035-47. PMID: 23518706.

" T+ Not dangerous goods.

LKT E5222 Endothelin-3, human 0.5 mg 600.1 Endogenous peptide, involved in vascular contraction. ET-B agonist. Rat endothelin-3 117399-93-6 ≥95% 2643.1 C121H168N26O33S4 CCC(C)C(C(=O)NC(C(C)CC)C(=O)NC(CC1=CNC2=CC=CC=C21)C(=O)O)NC(=O)C(CC(=O)O)NC(=O)C(CC(C)C)NC(=O)C(CC3=CN=CN3)NC(=O)C4CSSCC(C(=O)NC(C(=O)NC5CSSCC(C(=O)NC(C(=O)NC(C(=O)NC(C(=O)N4)CC6=CC=C(C=C6)O)CC7=CC=C(C=C7)O)C(C)C)NC(=O)C(NC(=O)C(NC(=O)C(NC(=O)C(NC(=O)C(NC(=O)C(NC(=O)C(NC5=O)CC8=CC=CC=C8)C(C)O)CC9=CC=C(C=C9)O)CCCCN)CC(=O)O)CCCCN)CCC(=O)O)C(C)O)N Ambient -20°C "Sato A, Ebina K. Endothelin-3 at low concentrations attenuates inflammatory responses via the endothelin B2 receptor. Inflamm Res. 2013 Apr;62(4):417-24. PMID: 23370722.

 

Spinella F, Rosanò L, Di Castro V, et al. Endothelin-1 and endothelin-3 promote invasive behavior via hypoxia-inducible factor-1alpha in human melanoma cells. Cancer Res. 2007 Feb 15;67(4):1725-34. PMID: 17308114.

 

Morgazo C, Perfume G, Legaz G, et al. Involvement of nitric oxide pathways in short term modulation of tyrosine hydroxylase activity by endothelins 1 and 3 in the rat anterior hypothalamus. Biochem Biophys Res Commun. 2005 Sep 2;334(3):796-802. PMID: 16023617.

" Not dangerous goods.

LKT E5222 Endothelin-3, human 1 mg 1020.2 Endogenous peptide, involved in vascular contraction. ET-B agonist. Rat endothelin-3 117399-93-6 ≥95% 2643.1 C121H168N26O33S4 CCC(C)C(C(=O)NC(C(C)CC)C(=O)NC(CC1=CNC2=CC=CC=C21)C(=O)O)NC(=O)C(CC(=O)O)NC(=O)C(CC(C)C)NC(=O)C(CC3=CN=CN3)NC(=O)C4CSSCC(C(=O)NC(C(=O)NC5CSSCC(C(=O)NC(C(=O)NC(C(=O)NC(C(=O)N4)CC6=CC=C(C=C6)O)CC7=CC=C(C=C7)O)C(C)C)NC(=O)C(NC(=O)C(NC(=O)C(NC(=O)C(NC(=O)C(NC(=O)C(NC(=O)C(NC5=O)CC8=CC=CC=C8)C(C)O)CC9=CC=C(C=C9)O)CCCCN)CC(=O)O)CCCCN)CCC(=O)O)C(C)O)N Ambient -20°C "Sato A, Ebina K. Endothelin-3 at low concentrations attenuates inflammatory responses via the endothelin B2 receptor. Inflamm Res. 2013 Apr;62(4):417-24. PMID: 23370722.

 

Spinella F, Rosanò L, Di Castro V, et al. Endothelin-1 and endothelin-3 promote invasive behavior via hypoxia-inducible factor-1alpha in human melanoma cells. Cancer Res. 2007 Feb 15;67(4):1725-34. PMID: 17308114.

 

Morgazo C, Perfume G, Legaz G, et al. Involvement of nitric oxide pathways in short term modulation of tyrosine hydroxylase activity by endothelins 1 and 3 in the rat anterior hypothalamus. Biochem Biophys Res Commun. 2005 Sep 2;334(3):796-802. PMID: 16023617.

" Not dangerous goods.

LKT E5222 Endothelin-3, human 2.5 mg 1800.2 Endogenous peptide, involved in vascular contraction. ET-B agonist. Rat endothelin-3 117399-93-6 ≥95% 2643.1 C121H168N26O33S4 CCC(C)C(C(=O)NC(C(C)CC)C(=O)NC(CC1=CNC2=CC=CC=C21)C(=O)O)NC(=O)C(CC(=O)O)NC(=O)C(CC(C)C)NC(=O)C(CC3=CN=CN3)NC(=O)C4CSSCC(C(=O)NC(C(=O)NC5CSSCC(C(=O)NC(C(=O)NC(C(=O)NC(C(=O)N4)CC6=CC=C(C=C6)O)CC7=CC=C(C=C7)O)C(C)C)NC(=O)C(NC(=O)C(NC(=O)C(NC(=O)C(NC(=O)C(NC(=O)C(NC(=O)C(NC5=O)CC8=CC=CC=C8)C(C)O)CC9=CC=C(C=C9)O)CCCCN)CC(=O)O)CCCCN)CCC(=O)O)C(C)O)N Ambient -20°C "Sato A, Ebina K. Endothelin-3 at low concentrations attenuates inflammatory responses via the endothelin B2 receptor. Inflamm Res. 2013 Apr;62(4):417-24. PMID: 23370722.

 

Spinella F, Rosanò L, Di Castro V, et al. Endothelin-1 and endothelin-3 promote invasive behavior via hypoxia-inducible factor-1alpha in human melanoma cells. Cancer Res. 2007 Feb 15;67(4):1725-34. PMID: 17308114.

 

Morgazo C, Perfume G, Legaz G, et al. Involvement of nitric oxide pathways in short term modulation of tyrosine hydroxylase activity by endothelins 1 and 3 in the rat anterior hypothalamus. Biochem Biophys Res Commun. 2005 Sep 2;334(3):796-802. PMID: 16023617.

" Not dangerous goods.

LKT E5240 Leu-Enkephalin 25 mg 72.1 Endogenous opioid peptide; δOR and μOR agonist. 1-5-b-Neoendorphin (human) (9CI) 58822-25-6 ≥95% 555.62 C28H37N5O7 CC(C)CC(C(=O)O)NC(=O)C(CC1=CC=CC=C1)NC(=O)CNC(=O)CNC(=O)C(CC2=CC=C(C=C2)O)N Ambient -20°C "Popov M, Abu Hammad I, Bachar T, et al. Delivery of analgesic peptides to the brain by nano-sized bolaamphiphilic vesicles made of monolayer membranes. Eur J Pharm Biopharm. 2013 Nov;85(3 Pt A):381-9. PMID: 23791683.

 

Crayton R, Soller W, Mattiasson A, et al. Exogenously administered opioids contract the female rat intrinsic urethral sphincter in vivo. Neurourol Urodyn. 2010 Jun;29(5):777-82. PMID: 19899147.

 

Holzer P. Opioid receptors in the gastrointestinal tract. Regul Pept. 2009 Jun 5;155(1-3):11-7. PMID: 19345246.

 

Del Borgo MP, Blanchfield JT, Toth I. Internalisation of the mu-opioid receptor by endomorphin-1 and leu-enkephalin is dependant on aromatic amino acid residues. Bioorg Med Chem. 2008 Apr 15;16(8):4341-6. PMID: 18329886.

" Not dangerous goods.

LKT E5240 Leu-Enkephalin 50 mg 123.1 Endogenous opioid peptide; δOR and μOR agonist. 1-5-b-Neoendorphin (human) (9CI) 58822-25-6 ≥95% 555.62 C28H37N5O7 CC(C)CC(C(=O)O)NC(=O)C(CC1=CC=CC=C1)NC(=O)CNC(=O)CNC(=O)C(CC2=CC=C(C=C2)O)N Ambient -20°C "Popov M, Abu Hammad I, Bachar T, et al. Delivery of analgesic peptides to the brain by nano-sized bolaamphiphilic vesicles made of monolayer membranes. Eur J Pharm Biopharm. 2013 Nov;85(3 Pt A):381-9. PMID: 23791683.

 

Crayton R, Soller W, Mattiasson A, et al. Exogenously administered opioids contract the female rat intrinsic urethral sphincter in vivo. Neurourol Urodyn. 2010 Jun;29(5):777-82. PMID: 19899147.

 

Holzer P. Opioid receptors in the gastrointestinal tract. Regul Pept. 2009 Jun 5;155(1-3):11-7. PMID: 19345246.

 

Del Borgo MP, Blanchfield JT, Toth I. Internalisation of the mu-opioid receptor by endomorphin-1 and leu-enkephalin is dependant on aromatic amino acid residues. Bioorg Med Chem. 2008 Apr 15;16(8):4341-6. PMID: 18329886.

" Not dangerous goods.

LKT E5240 Leu-Enkephalin 125 mg 216.1 Endogenous opioid peptide; δOR and μOR agonist. 1-5-b-Neoendorphin (human) (9CI) 58822-25-6 ≥95% 555.62 C28H37N5O7 CC(C)CC(C(=O)O)NC(=O)C(CC1=CC=CC=C1)NC(=O)CNC(=O)CNC(=O)C(CC2=CC=C(C=C2)O)N Ambient -20°C "Popov M, Abu Hammad I, Bachar T, et al. Delivery of analgesic peptides to the brain by nano-sized bolaamphiphilic vesicles made of monolayer membranes. Eur J Pharm Biopharm. 2013 Nov;85(3 Pt A):381-9. PMID: 23791683.

 

Crayton R, Soller W, Mattiasson A, et al. Exogenously administered opioids contract the female rat intrinsic urethral sphincter in vivo. Neurourol Urodyn. 2010 Jun;29(5):777-82. PMID: 19899147.

 

Holzer P. Opioid receptors in the gastrointestinal tract. Regul Pept. 2009 Jun 5;155(1-3):11-7. PMID: 19345246.

 

Del Borgo MP, Blanchfield JT, Toth I. Internalisation of the mu-opioid receptor by endomorphin-1 and leu-enkephalin is dependant on aromatic amino acid residues. Bioorg Med Chem. 2008 Apr 15;16(8):4341-6. PMID: 18329886.

" Not dangerous goods.

LKT E5241 Met-Enkephalin 25 mg 83.9 Endogenous opioid peptide; δOR and μOR agonist. Metenkefalin, Opioid growth factor, 1-5-Adrenorphin (human) 58569-55-4 ≥95% 573.67 C27H35N5O7S CSCCC(C(=O)O)NC(=O)C(CC1=CC=CC=C1)NC(=O)CNC(=O)CNC(=O)C(CC2=CC=C(C=C2)O)N Ambient -20°C "Gonzalez-Nunez V, Jimenez González A, Barreto-Valer K, et al. In vivo regulation of the μ opioid receptor: role of the endogenous opioid agents. Mol Med. 2013 Mar 5;19:7-17. PMID: 23348513.

 

Fanning RA, McMorrow JP, Campion DP, et al. Opioid mediated activity and expression of mu and delta opioid receptors in isolated human term non-labouring myometrium. Eur J Pharmacol. 2013 Jan 5;698(1-3):170-7. PMID: 23051674.

 

Hadjiconstantinou M, Neff NH. Nicotine and endogenous opioids: neurochemical and pharmacological evidence. Neuropharmacology. 2011 Jun;60(7-8):1209-20. PMID: 21108953.

 

Stagg NJ, Mata HP, Ibrahim MM, et al. Regular exercise reverses sensory hypersensitivity in a rat neuropathic pain model: role of endogenous opioids. Anesthesiology. 2011 Apr;114(4):940-8. PMID: 21386701.

 

Gredicak M, Supek F, Kralj M, et al. Computational structure-activity study directs synthesis of novel antitumor enkephalin analogs. Amino Acids. 2010 Apr;38(4):1185-91. PMID: 19639251.

 

Lee HK, Smith MD, Smith BJ, et al. Anticonvulsant Met-enkephalin analogues containing backbone spacers reveal alternative non-opioid signaling in the brain. ACS Chem Biol. 2009 Aug 21;4(8):659-71. PMID: 19634861.

" Not dangerous goods.

LKT E5241 Met-Enkephalin 50 mg 144 Endogenous opioid peptide; δOR and μOR agonist. Metenkefalin, Opioid growth factor, 1-5-Adrenorphin (human) 58569-55-4 ≥95% 573.67 C27H35N5O7S CSCCC(C(=O)O)NC(=O)C(CC1=CC=CC=C1)NC(=O)CNC(=O)CNC(=O)C(CC2=CC=C(C=C2)O)N Ambient -20°C "Gonzalez-Nunez V, Jimenez González A, Barreto-Valer K, et al. In vivo regulation of the μ opioid receptor: role of the endogenous opioid agents. Mol Med. 2013 Mar 5;19:7-17. PMID: 23348513.

 

Fanning RA, McMorrow JP, Campion DP, et al. Opioid mediated activity and expression of mu and delta opioid receptors in isolated human term non-labouring myometrium. Eur J Pharmacol. 2013 Jan 5;698(1-3):170-7. PMID: 23051674.

 

Hadjiconstantinou M, Neff NH. Nicotine and endogenous opioids: neurochemical and pharmacological evidence. Neuropharmacology. 2011 Jun;60(7-8):1209-20. PMID: 21108953.

 

Stagg NJ, Mata HP, Ibrahim MM, et al. Regular exercise reverses sensory hypersensitivity in a rat neuropathic pain model: role of endogenous opioids. Anesthesiology. 2011 Apr;114(4):940-8. PMID: 21386701.

 

Gredicak M, Supek F, Kralj M, et al. Computational structure-activity study directs synthesis of novel antitumor enkephalin analogs. Amino Acids. 2010 Apr;38(4):1185-91. PMID: 19639251.

 

Lee HK, Smith MD, Smith BJ, et al. Anticonvulsant Met-enkephalin analogues containing backbone spacers reveal alternative non-opioid signaling in the brain. ACS Chem Biol. 2009 Aug 21;4(8):659-71. PMID: 19634861.

" Not dangerous goods.

LKT E5241 Met-Enkephalin 125 mg 252.1 Endogenous opioid peptide; δOR and μOR agonist. Metenkefalin, Opioid growth factor, 1-5-Adrenorphin (human) 58569-55-4 ≥95% 573.67 C27H35N5O7S CSCCC(C(=O)O)NC(=O)C(CC1=CC=CC=C1)NC(=O)CNC(=O)CNC(=O)C(CC2=CC=C(C=C2)O)N Ambient -20°C "Gonzalez-Nunez V, Jimenez González A, Barreto-Valer K, et al. In vivo regulation of the μ opioid receptor: role of the endogenous opioid agents. Mol Med. 2013 Mar 5;19:7-17. PMID: 23348513.

 

Fanning RA, McMorrow JP, Campion DP, et al. Opioid mediated activity and expression of mu and delta opioid receptors in isolated human term non-labouring myometrium. Eur J Pharmacol. 2013 Jan 5;698(1-3):170-7. PMID: 23051674.

 

Hadjiconstantinou M, Neff NH. Nicotine and endogenous opioids: neurochemical and pharmacological evidence. Neuropharmacology. 2011 Jun;60(7-8):1209-20. PMID: 21108953.

 

Stagg NJ, Mata HP, Ibrahim MM, et al. Regular exercise reverses sensory hypersensitivity in a rat neuropathic pain model: role of endogenous opioids. Anesthesiology. 2011 Apr;114(4):940-8. PMID: 21386701.

 

Gredicak M, Supek F, Kralj M, et al. Computational structure-activity study directs synthesis of novel antitumor enkephalin analogs. Amino Acids. 2010 Apr;38(4):1185-91. PMID: 19639251.

 

Lee HK, Smith MD, Smith BJ, et al. Anticonvulsant Met-enkephalin analogues containing backbone spacers reveal alternative non-opioid signaling in the brain. ACS Chem Biol. 2009 Aug 21;4(8):659-71. PMID: 19634861.

" Not dangerous goods.

LKT E5276 Enterostatin, human 1 mg 63 Endogenous peptide, involved in dietary fat intake; F1-ATPase inhibitor. 117830-79-2 ≥97% 496.57 C21H86N3O6 CC(C(=O)N1CCCC1C(=O)NCC(=O)N2CCCC2C(=O)NC(CCCN=C(N)N)C(=O)O)N Ambient -20°C "Erlanson-Albertsson C. Fat-Rich Food Palatability and Appetite Regulation. In: Montmayeur JP, le Coutre J, editors. Fat Detection: Taste, Texture, and Post Ingestive Effects. Boca Raton (FL): CRC Press; 2010. Chapter 14. PMID: 21452478.

 

Takenaka Y, Shimano T, Mori T, et al. Enterostatin reduces serum cholesterol levels by way of a CCK(1) receptor-dependent mechanism. Peptides. 2008 Dec;29(12):2175-8. PMID: 18824202.

 

Lindqvist A, Berger K, Erlanson-Albertsson C. Enterostatin up-regulates the expression of the beta-subunit of F(1)F(o)-ATPase in the plasma membrane of INS-1 cells. Nutr Neurosci. 2008 Apr;11(2):55-60. PMID: 18510804.

" Not dangerous goods.

LKT E5276 Enterostatin, human 2 mg 104.9 Endogenous peptide, involved in dietary fat intake; F1-ATPase inhibitor. 117830-79-2 ≥97% 496.57 C21H86N3O6 CC(C(=O)N1CCCC1C(=O)NCC(=O)N2CCCC2C(=O)NC(CCCN=C(N)N)C(=O)O)N Ambient -20°C "Erlanson-Albertsson C. Fat-Rich Food Palatability and Appetite Regulation. In: Montmayeur JP, le Coutre J, editors. Fat Detection: Taste, Texture, and Post Ingestive Effects. Boca Raton (FL): CRC Press; 2010. Chapter 14. PMID: 21452478.

 

Takenaka Y, Shimano T, Mori T, et al. Enterostatin reduces serum cholesterol levels by way of a CCK(1) receptor-dependent mechanism. Peptides. 2008 Dec;29(12):2175-8. PMID: 18824202.

 

Lindqvist A, Berger K, Erlanson-Albertsson C. Enterostatin up-regulates the expression of the beta-subunit of F(1)F(o)-ATPase in the plasma membrane of INS-1 cells. Nutr Neurosci. 2008 Apr;11(2):55-60. PMID: 18510804.

" Not dangerous goods.

LKT E5276 Enterostatin, human 5 mg 186 Endogenous peptide, involved in dietary fat intake; F1-ATPase inhibitor. 117830-79-2 ≥97% 496.57 C21H86N3O6 CC(C(=O)N1CCCC1C(=O)NCC(=O)N2CCCC2C(=O)NC(CCCN=C(N)N)C(=O)O)N Ambient -20°C "Erlanson-Albertsson C. Fat-Rich Food Palatability and Appetite Regulation. In: Montmayeur JP, le Coutre J, editors. Fat Detection: Taste, Texture, and Post Ingestive Effects. Boca Raton (FL): CRC Press; 2010. Chapter 14. PMID: 21452478.

 

Takenaka Y, Shimano T, Mori T, et al. Enterostatin reduces serum cholesterol levels by way of a CCK(1) receptor-dependent mechanism. Peptides. 2008 Dec;29(12):2175-8. PMID: 18824202.

 

Lindqvist A, Berger K, Erlanson-Albertsson C. Enterostatin up-regulates the expression of the beta-subunit of F(1)F(o)-ATPase in the plasma membrane of INS-1 cells. Nutr Neurosci. 2008 Apr;11(2):55-60. PMID: 18510804.

" Not dangerous goods.

LKT E5277 Enterostatin, pig/rat 1 mg 63 Endogenous peptide, involved in dietary fat intake; F1-ATPase inhibitor. ≥98% 582.66 C25H4N8O8 CC(C)C(C(=O)N1CCCC1C(=O)NC(CC(=O)O)C(=O)N2CCCC2C(=O)NC(CCCN=C(N)N)C(=O)O)N Ambient -20°C "Erlanson-Albertsson C. Fat-Rich Food Palatability and Appetite Regulation. In: Montmayeur JP, le Coutre J, editors. Fat Detection: Taste, Texture, and Post Ingestive Effects. Boca Raton (FL): CRC Press; 2010. Chapter 14. PMID: 21452478.

 

Takenaka Y, Shimano T, Mori T, et al. Enterostatin reduces serum cholesterol levels by way of a CCK(1) receptor-dependent mechanism. Peptides. 2008 Dec;29(12):2175-8. PMID: 18824202.

 

Lindqvist A, Berger K, Erlanson-Albertsson C. Enterostatin up-regulates the expression of the beta-subunit of F(1)F(o)-ATPase in the plasma membrane of INS-1 cells. Nutr Neurosci. 2008 Apr;11(2):55-60. PMID: 18510804.

" Not dangerous goods.

LKT E5277 Enterostatin, pig/rat 2 mg 104.9 Endogenous peptide, involved in dietary fat intake; F1-ATPase inhibitor. ≥98% 582.66 C25H4N8O8 CC(C)C(C(=O)N1CCCC1C(=O)NC(CC(=O)O)C(=O)N2CCCC2C(=O)NC(CCCN=C(N)N)C(=O)O)N Ambient -20°C "Erlanson-Albertsson C. Fat-Rich Food Palatability and Appetite Regulation. In: Montmayeur JP, le Coutre J, editors. Fat Detection: Taste, Texture, and Post Ingestive Effects. Boca Raton (FL): CRC Press; 2010. Chapter 14. PMID: 21452478.

 

Takenaka Y, Shimano T, Mori T, et al. Enterostatin reduces serum cholesterol levels by way of a CCK(1) receptor-dependent mechanism. Peptides. 2008 Dec;29(12):2175-8. PMID: 18824202.

 

Lindqvist A, Berger K, Erlanson-Albertsson C. Enterostatin up-regulates the expression of the beta-subunit of F(1)F(o)-ATPase in the plasma membrane of INS-1 cells. Nutr Neurosci. 2008 Apr;11(2):55-60. PMID: 18510804.

" Not dangerous goods.

LKT E5277 Enterostatin, pig/rat 5 mg 186 Endogenous peptide, involved in dietary fat intake; F1-ATPase inhibitor. ≥98% 582.66 C25H4N8O8 CC(C)C(C(=O)N1CCCC1C(=O)NC(CC(=O)O)C(=O)N2CCCC2C(=O)NC(CCCN=C(N)N)C(=O)O)N Ambient -20°C "Erlanson-Albertsson C. Fat-Rich Food Palatability and Appetite Regulation. In: Montmayeur JP, le Coutre J, editors. Fat Detection: Taste, Texture, and Post Ingestive Effects. Boca Raton (FL): CRC Press; 2010. Chapter 14. PMID: 21452478.

 

Takenaka Y, Shimano T, Mori T, et al. Enterostatin reduces serum cholesterol levels by way of a CCK(1) receptor-dependent mechanism. Peptides. 2008 Dec;29(12):2175-8. PMID: 18824202.

 

Lindqvist A, Berger K, Erlanson-Albertsson C. Enterostatin up-regulates the expression of the beta-subunit of F(1)F(o)-ATPase in the plasma membrane of INS-1 cells. Nutr Neurosci. 2008 Apr;11(2):55-60. PMID: 18510804.

" Not dangerous goods.

LKT E5358 Enoxacin 500 mg 44 Fluoroquinolone; vacuolar H+ ATPase, topoisomerase IV, bacterial DNA gyrase inhibitor. 1-Ethyl-6-fluoro-1,4-dihydro-4-oxo-7-(1-piperazinyl)-1,8-naphthyridine-3-carboxylic acid Abenox; Bactidan; Comprecin; Flumark; Penetrex 74011-58-8 ≥98% 320.32 C15H17FN4O3 CCN1C=C(C(=O)C2=CC(=C(N=C21)N3CCNCC3)F)C(=O)O Ambient Ambient Insoluble in water. "Liu X, Qu X, Wu C, et al. The effect of enoxacin on osteoclastogenesis and reduction of titanium particle-induced osteolysis via suppression of JNK signaling pathway. Biomaterials. 2014 Jul;35(22):5721-30. PMID: 24767789.

 

Toro EJ, Zuo J, Ostrov DA, et al. Enoxacin directly inhibits osteoclastogenesis without inducing apoptosis. J Biol Chem. 2012 May 18;287(21):17894-904. PMID: 22474295.

 

Zuma AA, Cavalcanti DP, Maia MC, et al. Effect of topoisomerase inhibitors and DNA-binding drugs on the cell proliferation and ultrastructure of Trypanosoma cruzi. Int J Antimicrob Agents. 2011 May;37(5):449-56. PMID: 21292448.

 

Koseki N, Deguchi J, Yamashita A, et al. Establishment fo a novel experimental protocol for drug-induced seizure liability screening based on a locomotor activity assay in zebrafish. J Toxicol Sci. 2014 Aug;39(4):579-600. PMID: 25056783.

" Xi Not dangerous goods.

LKT E5358 Enoxacin 1 g 73.1 Fluoroquinolone; vacuolar H+ ATPase, topoisomerase IV, bacterial DNA gyrase inhibitor. 1-Ethyl-6-fluoro-1,4-dihydro-4-oxo-7-(1-piperazinyl)-1,8-naphthyridine-3-carboxylic acid Abenox; Bactidan; Comprecin; Flumark; Penetrex 74011-58-8 ≥98% 320.32 C15H17FN4O3 CCN1C=C(C(=O)C2=CC(=C(N=C21)N3CCNCC3)F)C(=O)O Ambient Ambient Insoluble in water. "Liu X, Qu X, Wu C, et al. The effect of enoxacin on osteoclastogenesis and reduction of titanium particle-induced osteolysis via suppression of JNK signaling pathway. Biomaterials. 2014 Jul;35(22):5721-30. PMID: 24767789.

 

Toro EJ, Zuo J, Ostrov DA, et al. Enoxacin directly inhibits osteoclastogenesis without inducing apoptosis. J Biol Chem. 2012 May 18;287(21):17894-904. PMID: 22474295.

 

Zuma AA, Cavalcanti DP, Maia MC, et al. Effect of topoisomerase inhibitors and DNA-binding drugs on the cell proliferation and ultrastructure of Trypanosoma cruzi. Int J Antimicrob Agents. 2011 May;37(5):449-56. PMID: 21292448.

 

Koseki N, Deguchi J, Yamashita A, et al. Establishment fo a novel experimental protocol for drug-induced seizure liability screening based on a locomotor activity assay in zebrafish. J Toxicol Sci. 2014 Aug;39(4):579-600. PMID: 25056783.

" Xi Not dangerous goods.

LKT E5369 Enrofloxacin 5 g 92.2 Fluoroquinolone; bacterial DNA gyrase inhibitor. 1,4-Dihydro-1-cyclopropyl-7-(4-ethyl-1-piperazinyl)-6-fluoro-4-oxo-3-quinolinecarboxylic acid; Baytril 93106-60-6 ≥98% 359.39 C19H22FN3O3 CCN1CCN(CC1)C2=C(C=C3C(=C2)N(C=C(C3=O)C(=O)O)C4CC4)F Ambient Ambient Slightly soluble in water. "Cengiz M, Sahinturk P, Sonal S, et al. In vitro bactericidal activity of enrofloxacin against gyrA mutant and qnr-containing Escherichia coli isolates from animals. Vet Rec. 2013 May 4;172(18):474. PMID: 23605176.

 

Rzedzicki J, Boś M, Kolasa A. Influence of antibiotics on growth dynamics and movement ability of Salmonella rods. Pol J Vet Sci. 2004;7(4):267-74. PMID: 15633786.

" None Not dangerous goods.

LKT E5369 Enrofloxacin 10 g 144.1 Fluoroquinolone; bacterial DNA gyrase inhibitor. 1,4-Dihydro-1-cyclopropyl-7-(4-ethyl-1-piperazinyl)-6-fluoro-4-oxo-3-quinolinecarboxylic acid; Baytril 93106-60-6 ≥98% 359.39 C19H22FN3O3 CCN1CCN(CC1)C2=C(C=C3C(=C2)N(C=C(C3=O)C(=O)O)C4CC4)F Ambient Ambient Slightly soluble in water. "Cengiz M, Sahinturk P, Sonal S, et al. In vitro bactericidal activity of enrofloxacin against gyrA mutant and qnr-containing Escherichia coli isolates from animals. Vet Rec. 2013 May 4;172(18):474. PMID: 23605176.

 

Rzedzicki J, Boś M, Kolasa A. Influence of antibiotics on growth dynamics and movement ability of Salmonella rods. Pol J Vet Sci. 2004;7(4):267-74. PMID: 15633786.

" None Not dangerous goods.

LKT E5369 Enrofloxacin 50 g 570.8 Fluoroquinolone; bacterial DNA gyrase inhibitor. 1,4-Dihydro-1-cyclopropyl-7-(4-ethyl-1-piperazinyl)-6-fluoro-4-oxo-3-quinolinecarboxylic acid; Baytril 93106-60-6 ≥98% 359.39 C19H22FN3O3 CCN1CCN(CC1)C2=C(C=C3C(=C2)N(C=C(C3=O)C(=O)O)C4CC4)F Ambient Ambient Slightly soluble in water. "Cengiz M, Sahinturk P, Sonal S, et al. In vitro bactericidal activity of enrofloxacin against gyrA mutant and qnr-containing Escherichia coli isolates from animals. Vet Rec. 2013 May 4;172(18):474. PMID: 23605176.

 

Rzedzicki J, Boś M, Kolasa A. Influence of antibiotics on growth dynamics and movement ability of Salmonella rods. Pol J Vet Sci. 2004;7(4):267-74. PMID: 15633786.

" None Not dangerous goods.

LKT E5456 Enocitabine 25 mg 176.6 Cytarabine derivative, nucleoside (cytosine) analog; DNA chain terminator. N4-behenoyl-1-beta-D-arabinofuranosylcytosine; BH-AC 55726-47-1 ≥98% 565.78 C31H55N3O6 CCCCCCCCCCCCCCCCCCCCCC(=O)NC1=NC(=O)N(C=C1)C2C(C(C(O2)CO)O)O Ambient Ambient "Ito Y, Wakita A, Takada S, et al. Phase 1 trial of gemtuzumab ozogamicin in combination with enocitabine and daunorubicin for elderly patients with relapsed or refractory acute myeloid leukemia: Japan Adult Leukemia Study Group (JALSG)-GML208 study. Int J Hematol. 2012 Oct;96(4):485-91. PMID: 22956429.

 

Hamada A, Kawaguchi T, Nakano M. Clinical pharmacokinetics of cytarabine formulations. Clin Pharmacokinet. 2002;41(10):705-18. PMID: 12162758.

 

Nakamura K, Eizuru Y, Kumura K, et al. Antiviral effect of antileukemic drugs N4-behenoyl-1-beta-D-arabinofuranosylcytosine (BH-AC) and 2,2'-anhydro-1-beta-D-arabinofuranosylcytosine (cyclo-C) against human cytomegalovirus. J Med Virol. 1990 Jun;31(2):141-7. PMID: 1696958.

 

Maehara Y, Kusumoto T, Kusumoto H, et al. In vitro sensitivity of various human tumors to 1-beta-D-arabinofuranosylcytosine and N4-behenoyl-1-beta-D-arabinofuranosylcytosine. Chemotherapy. 1989;35(3):181-6. PMID: 2766858.

 

Higashigawa M, Ochiai H, Ohkubo T, et al. Incorporation of N4-behenoyl-1-beta-D-arabinofuranosylcytosine into DNA as 1-beta-D-arabinofuranosylcytosine. Med Oncol Tumor Pharmacother. 1988;5(4):265-71. PMID: 2848163.

" Not dangerous goods.

LKT E5456 Enocitabine 100 mg 557.1 Cytarabine derivative, nucleoside (cytosine) analog; DNA chain terminator. N4-behenoyl-1-beta-D-arabinofuranosylcytosine; BH-AC 55726-47-1 ≥98% 565.78 C31H55N3O6 CCCCCCCCCCCCCCCCCCCCCC(=O)NC1=NC(=O)N(C=C1)C2C(C(C(O2)CO)O)O Ambient Ambient "Ito Y, Wakita A, Takada S, et al. Phase 1 trial of gemtuzumab ozogamicin in combination with enocitabine and daunorubicin for elderly patients with relapsed or refractory acute myeloid leukemia: Japan Adult Leukemia Study Group (JALSG)-GML208 study. Int J Hematol. 2012 Oct;96(4):485-91. PMID: 22956429.

 

Hamada A, Kawaguchi T, Nakano M. Clinical pharmacokinetics of cytarabine formulations. Clin Pharmacokinet. 2002;41(10):705-18. PMID: 12162758.

 

Nakamura K, Eizuru Y, Kumura K, et al. Antiviral effect of antileukemic drugs N4-behenoyl-1-beta-D-arabinofuranosylcytosine (BH-AC) and 2,2'-anhydro-1-beta-D-arabinofuranosylcytosine (cyclo-C) against human cytomegalovirus. J Med Virol. 1990 Jun;31(2):141-7. PMID: 1696958.

 

Maehara Y, Kusumoto T, Kusumoto H, et al. In vitro sensitivity of various human tumors to 1-beta-D-arabinofuranosylcytosine and N4-behenoyl-1-beta-D-arabinofuranosylcytosine. Chemotherapy. 1989;35(3):181-6. PMID: 2766858.

 

Higashigawa M, Ochiai H, Ohkubo T, et al. Incorporation of N4-behenoyl-1-beta-D-arabinofuranosylcytosine into DNA as 1-beta-D-arabinofuranosylcytosine. Med Oncol Tumor Pharmacother. 1988;5(4):265-71. PMID: 2848163.

" Not dangerous goods.

LKT E5456 Enocitabine 250 mg 978.5 Cytarabine derivative, nucleoside (cytosine) analog; DNA chain terminator. N4-behenoyl-1-beta-D-arabinofuranosylcytosine; BH-AC 55726-47-1 ≥98% 565.78 C31H55N3O6 CCCCCCCCCCCCCCCCCCCCCC(=O)NC1=NC(=O)N(C=C1)C2C(C(C(O2)CO)O)O Ambient Ambient "Ito Y, Wakita A, Takada S, et al. Phase 1 trial of gemtuzumab ozogamicin in combination with enocitabine and daunorubicin for elderly patients with relapsed or refractory acute myeloid leukemia: Japan Adult Leukemia Study Group (JALSG)-GML208 study. Int J Hematol. 2012 Oct;96(4):485-91. PMID: 22956429.

 

Hamada A, Kawaguchi T, Nakano M. Clinical pharmacokinetics of cytarabine formulations. Clin Pharmacokinet. 2002;41(10):705-18. PMID: 12162758.

 

Nakamura K, Eizuru Y, Kumura K, et al. Antiviral effect of antileukemic drugs N4-behenoyl-1-beta-D-arabinofuranosylcytosine (BH-AC) and 2,2'-anhydro-1-beta-D-arabinofuranosylcytosine (cyclo-C) against human cytomegalovirus. J Med Virol. 1990 Jun;31(2):141-7. PMID: 1696958.

 

Maehara Y, Kusumoto T, Kusumoto H, et al. In vitro sensitivity of various human tumors to 1-beta-D-arabinofuranosylcytosine and N4-behenoyl-1-beta-D-arabinofuranosylcytosine. Chemotherapy. 1989;35(3):181-6. PMID: 2766858.

 

Higashigawa M, Ochiai H, Ohkubo T, et al. Incorporation of N4-behenoyl-1-beta-D-arabinofuranosylcytosine into DNA as 1-beta-D-arabinofuranosylcytosine. Med Oncol Tumor Pharmacother. 1988;5(4):265-71. PMID: 2848163.

" Not dangerous goods.

LKT E5575 Entacapone 25 mg 83.7 COMT inhibitor. (E)-2-cyano-3-(3,4-dihydroxy-5-nitrophenyl)-N,N-diethylprop-2-enamide 116314-67-1 ≥98% 305.29 C14H15N3O5 CCN(CC)C(=O)C(=CC1=CC(=C(C(=C1)O)O)[N+](=O)[O-])C#N Ambient Ambient "Di Giovanni S, Eleuteri S, Paleologou KE, et al. Entacapone and tolcapone, two catechol O-methyltransferase inhibitors, block fibril formation of alpha-synuclein and beta-amyloid and protect against amyloid-induced toxicity. J Biol Chem. 2010 May 14;285(20):14941-54. PMID: 20150427.

 

Hamaue N, Ogata A, Terado M, et al. Entacapone, a catechol-O-methyltransferase inhibitor, improves the motor activity and dopamine content of basal ganglia in a rat model of Parkinson's disease induced by Japanese encephalitis virus. Brain Res. 2010 Jan 14;1309:110-5. PMID: 19879254.

 

Deleu D, Northway MG, Hanssens Y. Clinical pharmacokinetic and pharmacodynamic properties of drugs used in the treatment of Parkinson's disease. Clin Pharmacokinet. 2002;41(4):261-309. PMID: 11978145.

 

Törnwall M, Tuomainen P, Männistö PT. Modulation of rat brain endogenous dopamine metabolism by new inhibitors of catechol O-methyltransferase. Eur J Pharmacol. 1993 Aug 3;239(1-3):39-45. PMID: 8223912.

" Not dangerous goods.

LKT E5575 Entacapone 100 mg 242.7 COMT inhibitor. (E)-2-cyano-3-(3,4-dihydroxy-5-nitrophenyl)-N,N-diethylprop-2-enamide 116314-67-1 ≥98% 305.29 C14H15N3O5 CCN(CC)C(=O)C(=CC1=CC(=C(C(=C1)O)O)[N+](=O)[O-])C#N Ambient Ambient "Di Giovanni S, Eleuteri S, Paleologou KE, et al. Entacapone and tolcapone, two catechol O-methyltransferase inhibitors, block fibril formation of alpha-synuclein and beta-amyloid and protect against amyloid-induced toxicity. J Biol Chem. 2010 May 14;285(20):14941-54. PMID: 20150427.

 

Hamaue N, Ogata A, Terado M, et al. Entacapone, a catechol-O-methyltransferase inhibitor, improves the motor activity and dopamine content of basal ganglia in a rat model of Parkinson's disease induced by Japanese encephalitis virus. Brain Res. 2010 Jan 14;1309:110-5. PMID: 19879254.

 

Deleu D, Northway MG, Hanssens Y. Clinical pharmacokinetic and pharmacodynamic properties of drugs used in the treatment of Parkinson's disease. Clin Pharmacokinet. 2002;41(4):261-309. PMID: 11978145.

 

Törnwall M, Tuomainen P, Männistö PT. Modulation of rat brain endogenous dopamine metabolism by new inhibitors of catechol O-methyltransferase. Eur J Pharmacol. 1993 Aug 3;239(1-3):39-45. PMID: 8223912.

" Not dangerous goods.

LKT E5575 Entacapone 500 mg 879.7 COMT inhibitor. (E)-2-cyano-3-(3,4-dihydroxy-5-nitrophenyl)-N,N-diethylprop-2-enamide 116314-67-1 ≥98% 305.29 C14H15N3O5 CCN(CC)C(=O)C(=CC1=CC(=C(C(=C1)O)O)[N+](=O)[O-])C#N Ambient Ambient "Di Giovanni S, Eleuteri S, Paleologou KE, et al. Entacapone and tolcapone, two catechol O-methyltransferase inhibitors, block fibril formation of alpha-synuclein and beta-amyloid and protect against amyloid-induced toxicity. J Biol Chem. 2010 May 14;285(20):14941-54. PMID: 20150427.

 

Hamaue N, Ogata A, Terado M, et al. Entacapone, a catechol-O-methyltransferase inhibitor, improves the motor activity and dopamine content of basal ganglia in a rat model of Parkinson's disease induced by Japanese encephalitis virus. Brain Res. 2010 Jan 14;1309:110-5. PMID: 19879254.

 

Deleu D, Northway MG, Hanssens Y. Clinical pharmacokinetic and pharmacodynamic properties of drugs used in the treatment of Parkinson's disease. Clin Pharmacokinet. 2002;41(4):261-309. PMID: 11978145.

 

Törnwall M, Tuomainen P, Männistö PT. Modulation of rat brain endogenous dopamine metabolism by new inhibitors of catechol O-methyltransferase. Eur J Pharmacol. 1993 Aug 3;239(1-3):39-45. PMID: 8223912.

" Not dangerous goods.

LKT E5576 Entecavir 1 mg 58.7 Nucleoside (deoxyguanosine) analog; DNA chain terminator, RT inhibitor. 2-amino-9-[(1S,3R,4S)-4-hydroxy-3-(hydroxymethyl)-2-methylidenecyclopentyl]-3H-purin-6-one 142217-69-4 ≥97% 277.28 C12H15N5O3 C=C1C(CC(C1CO)O)N2C=NC3=C2NC(=NC3=O)N Ambient Ambient "Water (2-3 mg/ml)

DMSO

Methanol" "Yurdaydin C. Entecavir: a step forward in combating hepatitis B disease. Expert Opin Pharmacother. 2008 Dec;9(17):3095-109. PMID: 19006481.

 

Cheng PN, Chang TT. Entecavir: a potent antiviral with minimal long-term resistance in nucleoside-naive chronic hepatitis B patients. Expert Rev Anti Infect Ther. 2008 Oct;6(5):569-79. PMID: 18847396.

 

Domaoal RA, McMahon M, Thio CL, et al. Pre-steady-state kinetic studies establish entecavir 5'-triphosphate as a substrate for HIV-1 reverse transcriptase. J Biol Chem. 2008 Feb 29;283(9):5452-9. PMID: 17962184.

 

Langley DR, Walsh AW, Baldick CJ, et al. Inhibition of hepatitis B virus polymerase by entecavir. J Virol. 2007 Apr;81(8):3992-4001. PMID: 17267485.

" Not dangerous goods.

LKT E5576 Entecavir 5 mg 200.8 Nucleoside (deoxyguanosine) analog; DNA chain terminator, RT inhibitor. 2-amino-9-[(1S,3R,4S)-4-hydroxy-3-(hydroxymethyl)-2-methylidenecyclopentyl]-3H-purin-6-one 142217-69-4 ≥97% 277.28 C12H15N5O3 C=C1C(CC(C1CO)O)N2C=NC3=C2NC(=NC3=O)N Ambient Ambient "Water (2-3 mg/ml)

DMSO

Methanol" "Yurdaydin C. Entecavir: a step forward in combating hepatitis B disease. Expert Opin Pharmacother. 2008 Dec;9(17):3095-109. PMID: 19006481.

 

Cheng PN, Chang TT. Entecavir: a potent antiviral with minimal long-term resistance in nucleoside-naive chronic hepatitis B patients. Expert Rev Anti Infect Ther. 2008 Oct;6(5):569-79. PMID: 18847396.

 

Domaoal RA, McMahon M, Thio CL, et al. Pre-steady-state kinetic studies establish entecavir 5'-triphosphate as a substrate for HIV-1 reverse transcriptase. J Biol Chem. 2008 Feb 29;283(9):5452-9. PMID: 17962184.

 

Langley DR, Walsh AW, Baldick CJ, et al. Inhibition of hepatitis B virus polymerase by entecavir. J Virol. 2007 Apr;81(8):3992-4001. PMID: 17267485.

" Not dangerous goods.

LKT E5576 Entecavir 25 mg 669.7 Nucleoside (deoxyguanosine) analog; DNA chain terminator, RT inhibitor. 2-amino-9-[(1S,3R,4S)-4-hydroxy-3-(hydroxymethyl)-2-methylidenecyclopentyl]-3H-purin-6-one 142217-69-4 ≥97% 277.28 C12H15N5O3 C=C1C(CC(C1CO)O)N2C=NC3=C2NC(=NC3=O)N Ambient Ambient "Water (2-3 mg/ml)

DMSO

Methanol" "Yurdaydin C. Entecavir: a step forward in combating hepatitis B disease. Expert Opin Pharmacother. 2008 Dec;9(17):3095-109. PMID: 19006481.

 

Cheng PN, Chang TT. Entecavir: a potent antiviral with minimal long-term resistance in nucleoside-naive chronic hepatitis B patients. Expert Rev Anti Infect Ther. 2008 Oct;6(5):569-79. PMID: 18847396.

 

Domaoal RA, McMahon M, Thio CL, et al. Pre-steady-state kinetic studies establish entecavir 5'-triphosphate as a substrate for HIV-1 reverse transcriptase. J Biol Chem. 2008 Feb 29;283(9):5452-9. PMID: 17962184.

 

Langley DR, Walsh AW, Baldick CJ, et al. Inhibition of hepatitis B virus polymerase by entecavir. J Virol. 2007 Apr;81(8):3992-4001. PMID: 17267485.

" Not dangerous goods.

LKT E6231 (−)-Epicatechin 1 mg 40.7 Flavanol originally found in Camilla (green tea). 2-(3,4-Dihydroxyphenyl)-3,4-dihydro-2H-1-benzo- pyran-3,5,7-triol Epicatechin; Epicatechol  490-46-0 ≥93% 290.27 C15H14O6 C1C(C(OC2=CC(=CC(=C21)O)O)C3=CC(=C(C=C3)O)O)O Ambient -20°C Soluble in water or alcohol. "Yamazaki KG, Andreyev AY, Ortiz-Vilchis P, et al. Intravenous (-)-epicatechin reduces myocardial ischemic injury by protecting mitochondrial function. Int J Cardiol. 2014 Aug 1;175(2):297-306. PMID: 24908200.

 

Zeng YQ, Wang YJ, Zhou XF. Effects of (-)Epicatechin on the Pathology of APP/PS1 Transgenic Mice. Front Neurol. 2014 May 9;5:69. PMID: 24847308.

 

Morrison M, van der Heijden R, Heeringa P, et al. Epicatechin attenuates atherosclerosis and exerts anti-inflammatory effects on diet-induced human-CRP and NFκB in vivo. Atherosclerosis. 2014 Mar;233(1):149-56. PMID: 24529136.

 

Butt MS, Ahmad RS, Sultan MT, et al. Green tea and anticancer perspectives: Updates from last decade. Crit Rev Food Sci Nutr. 2013 Sep 20. [Epub ahead of print]. PMID: 24915354.

" Xi Not dangerous goods.

LKT E6231 (−)-Epicatechin 5 mg 156.2 Flavanol originally found in Camilla (green tea). 2-(3,4-Dihydroxyphenyl)-3,4-dihydro-2H-1-benzo- pyran-3,5,7-triol Epicatechin; Epicatechol  490-46-0 ≥93% 290.27 C15H14O6 C1C(C(OC2=CC(=CC(=C21)O)O)C3=CC(=C(C=C3)O)O)O Ambient -20°C Soluble in water or alcohol. "Yamazaki KG, Andreyev AY, Ortiz-Vilchis P, et al. Intravenous (-)-epicatechin reduces myocardial ischemic injury by protecting mitochondrial function. Int J Cardiol. 2014 Aug 1;175(2):297-306. PMID: 24908200.

 

Zeng YQ, Wang YJ, Zhou XF. Effects of (-)Epicatechin on the Pathology of APP/PS1 Transgenic Mice. Front Neurol. 2014 May 9;5:69. PMID: 24847308.

 

Morrison M, van der Heijden R, Heeringa P, et al. Epicatechin attenuates atherosclerosis and exerts anti-inflammatory effects on diet-induced human-CRP and NFκB in vivo. Atherosclerosis. 2014 Mar;233(1):149-56. PMID: 24529136.

 

Butt MS, Ahmad RS, Sultan MT, et al. Green tea and anticancer perspectives: Updates from last decade. Crit Rev Food Sci Nutr. 2013 Sep 20. [Epub ahead of print]. PMID: 24915354.

" Xi Not dangerous goods.

LKT E6232 (−)-Epicatechin gallate 1 mg 34.8 Flavanol originally found in Camilla (green tea); CB1 agonist. 3,4,5-Trihydroxybenzoic acid, (2R,3R)-3,4- dihydro-5,7-dihydroxy-2-(3,4,5-trihydroxyphenyl)-2-H-1-benzopyran-3-yl ester ECG 1257-08-5 ≥98% 442.37 C22H18O10 C1C(C(OC2=CC(=CC(=C21)O)O)C3=CC(=C(C=C3)O)O)OC(=O)C4=CC(=C(C(=C4)O)O)O Ambient -20°C Soluble in water or alcohol. "Nakanishi T, Mukai K, Hosokawa Y, et al. Catechins inhibit vascular endothelial growth factor production and cyclooxygenase-2 expression in human dental pulp cells. Int Endod J. 2014 May 21. [Epub ahead of print]. PMID: 24847951.

 

Ly BT, Chi HT, Yamagishi M, et al. Inhibition of FLT3 expression by green tea catechins in FLT3 mutated-AML cells. PLoS One. 2013 Jun 20;8(6):e66378. PMID: 23840454.

 

Korte G, Dreiseitel A, Schreier P, et al. Tea catechins' affinity for human cannabinoid receptors. Phytomedicine. 2010 Jan;17(1):19-22. PMID: 19897346.

" None Not dangerous goods.

LKT E6232 (−)-Epicatechin gallate 5 mg 115.4 Flavanol originally found in Camilla (green tea); CB1 agonist. 3,4,5-Trihydroxybenzoic acid, (2R,3R)-3,4- dihydro-5,7-dihydroxy-2-(3,4,5-trihydroxyphenyl)-2-H-1-benzopyran-3-yl ester ECG 1257-08-5 ≥98% 442.37 C22H18O10 C1C(C(OC2=CC(=CC(=C21)O)O)C3=CC(=C(C=C3)O)O)OC(=O)C4=CC(=C(C(=C4)O)O)O Ambient -20°C Soluble in water or alcohol. "Nakanishi T, Mukai K, Hosokawa Y, et al. Catechins inhibit vascular endothelial growth factor production and cyclooxygenase-2 expression in human dental pulp cells. Int Endod J. 2014 May 21. [Epub ahead of print]. PMID: 24847951.

 

Ly BT, Chi HT, Yamagishi M, et al. Inhibition of FLT3 expression by green tea catechins in FLT3 mutated-AML cells. PLoS One. 2013 Jun 20;8(6):e66378. PMID: 23840454.

 

Korte G, Dreiseitel A, Schreier P, et al. Tea catechins' affinity for human cannabinoid receptors. Phytomedicine. 2010 Jan;17(1):19-22. PMID: 19897346.

" None Not dangerous goods.

LKT E6233 (−)-Epigallocatechin 1 mg 32.1 Flavanol originally found in Camilla (green tea); CB1 agonist. (-)-3,3',4',5,5',7-Flavanhexol; Epigallocatechin; Epigallocatechol 970-74-1 ≥98% 306.27 C15H14O7 C1C(C(OC2=CC(=CC(=C21)O)O)C3=CC(=C(C(=C3)O)O)O)O Ambient 4°C Soluble in water or alcohol. "Chen XQ, Wang XB, Guan RF, et al. Blood anticoagulation and antiplatelet activity of green tea (-)-epigallocatechin (EGC) in mice. Food Funct. 2013 Oct;4(10):1521-5. PMID: 24056410.

 

Ly BT, Chi HT, Yamagishi M, et al. Inhibition of FLT3 expression by green tea catechins in FLT3 mutated-AML cells. PLoS One. 2013 Jun 20;8(6):e66378. PMID: 23840454.

 

Ko CH, Siu WS, Wong HL, et al. Pro-bone and antifat effects of green tea and its polyphenol, epigallocatechin, in rat mesenchymal stem cells in vitro. J Agric Food Chem. 2011 Sep 28;59(18):9870-6. PMID: 21877759.

 

Korte G, Dreiseitel A, Schreier P, et al. Tea catechins' affinity for human cannabinoid receptors. Phytomedicine. 2010 Jan;17(1):19-22. PMID: 19897346.

 

Kushima Y, Iida K, Nagaoka Y, et al. Inhibitory effect of (-)-epigallocatechin and (-)-epigallocatechin gallate against heregulin beta1-induced migration/invasion of the MCF-7 breast carcinoma cell line. Biol Pharm Bull. 2009 May;32(5):899-904. PMID: 19420761.

" None Not dangerous goods.

LKT E6233 (−)-Epigallocatechin 5 mg 115.4 Flavanol originally found in Camilla (green tea); CB1 agonist. (-)-3,3',4',5,5',7-Flavanhexol; Epigallocatechin; Epigallocatechol 970-74-1 ≥98% 306.27 C15H14O7 C1C(C(OC2=CC(=CC(=C21)O)O)C3=CC(=C(C(=C3)O)O)O)O Ambient 4°C Soluble in water or alcohol. "Chen XQ, Wang XB, Guan RF, et al. Blood anticoagulation and antiplatelet activity of green tea (-)-epigallocatechin (EGC) in mice. Food Funct. 2013 Oct;4(10):1521-5. PMID: 24056410.

 

Ly BT, Chi HT, Yamagishi M, et al. Inhibition of FLT3 expression by green tea catechins in FLT3 mutated-AML cells. PLoS One. 2013 Jun 20;8(6):e66378. PMID: 23840454.

 

Ko CH, Siu WS, Wong HL, et al. Pro-bone and antifat effects of green tea and its polyphenol, epigallocatechin, in rat mesenchymal stem cells in vitro. J Agric Food Chem. 2011 Sep 28;59(18):9870-6. PMID: 21877759.

 

Korte G, Dreiseitel A, Schreier P, et al. Tea catechins' affinity for human cannabinoid receptors. Phytomedicine. 2010 Jan;17(1):19-22. PMID: 19897346.

 

Kushima Y, Iida K, Nagaoka Y, et al. Inhibitory effect of (-)-epigallocatechin and (-)-epigallocatechin gallate against heregulin beta1-induced migration/invasion of the MCF-7 breast carcinoma cell line. Biol Pharm Bull. 2009 May;32(5):899-904. PMID: 19420761.

" None Not dangerous goods.

LKT E6235 Epirubicin Hydrochloride 1 mg 47.6 Anthracycline, DNA intercalator; topoisomerase II inhibitor. "10-((3-amino-2,3,6-trideoxy-beta-L-arabino-

hexopyranosyl)oxy)-7,8,9,10-tetrahydro-

6,8,11-trihydroxy-8-(hydroxyacetyl)-1-methoxy-

(8S-cis)-5,12-naphthacenedione hydrochloride" 4'-Epiadriamycin; Epiadriamycin; Ridorubicin, Ellence, Farmorubicin, Pharmorubicin 56390-09-1 ≥90% 579.99 C27H29NO11 HCl CC1C(C(CC(O1)OC2CC(CC3=C(C4=C(C(=C23)O)C(=O)C5=C(C4=O)C=CC=C5OC)O)(C(=O)CO)O)N)O.Cl Solution is sensitive to light Ambient 4°C Soluble in water, methanol.  Insoluble in acetone "Monteiro LJ, Khongkow P, Kongsema M, et al. The Forkhead Box M1 protein regulates BRIP1 expression and DNA damage repair in epirubicin treatment. Oncogene. 2013 Sep 26;32(39):4634-45. PMID: 23108394.

 

Conte PF, Gennari A, Landucci E, et al. Role of epirubicin in advanced breast cancer. Clin Breast Cancer. 2000 Sep;1 Suppl 1:S46-51. PMID: 11970749.

" Xn Not dangerous goods.

LKT E6235 Epirubicin Hydrochloride 5 mg 95.1 Anthracycline, DNA intercalator; topoisomerase II inhibitor. "10-((3-amino-2,3,6-trideoxy-beta-L-arabino-

hexopyranosyl)oxy)-7,8,9,10-tetrahydro-

6,8,11-trihydroxy-8-(hydroxyacetyl)-1-methoxy-

(8S-cis)-5,12-naphthacenedione hydrochloride" 4'-Epiadriamycin; Epiadriamycin; Ridorubicin, Ellence, Farmorubicin, Pharmorubicin 56390-09-1 ≥90% 579.99 C27H29NO11 HCl CC1C(C(CC(O1)OC2CC(CC3=C(C4=C(C(=C23)O)C(=O)C5=C(C4=O)C=CC=C5OC)O)(C(=O)CO)O)N)O.Cl Solution is sensitive to light Ambient 4°C Soluble in water, methanol.  Insoluble in acetone "Monteiro LJ, Khongkow P, Kongsema M, et al. The Forkhead Box M1 protein regulates BRIP1 expression and DNA damage repair in epirubicin treatment. Oncogene. 2013 Sep 26;32(39):4634-45. PMID: 23108394.

 

Conte PF, Gennari A, Landucci E, et al. Role of epirubicin in advanced breast cancer. Clin Breast Cancer. 2000 Sep;1 Suppl 1:S46-51. PMID: 11970749.

" Xn Not dangerous goods.

LKT E6235 Epirubicin Hydrochloride 10 mg 163.2 Anthracycline, DNA intercalator; topoisomerase II inhibitor. "10-((3-amino-2,3,6-trideoxy-beta-L-arabino-

hexopyranosyl)oxy)-7,8,9,10-tetrahydro-

6,8,11-trihydroxy-8-(hydroxyacetyl)-1-methoxy-

(8S-cis)-5,12-naphthacenedione hydrochloride" 4'-Epiadriamycin; Epiadriamycin; Ridorubicin, Ellence, Farmorubicin, Pharmorubicin 56390-09-1 ≥90% 579.99 C27H29NO11 HCl CC1C(C(CC(O1)OC2CC(CC3=C(C4=C(C(=C23)O)C(=O)C5=C(C4=O)C=CC=C5OC)O)(C(=O)CO)O)N)O.Cl Solution is sensitive to light Ambient 4°C Soluble in water, methanol.  Insoluble in acetone "Monteiro LJ, Khongkow P, Kongsema M, et al. The Forkhead Box M1 protein regulates BRIP1 expression and DNA damage repair in epirubicin treatment. Oncogene. 2013 Sep 26;32(39):4634-45. PMID: 23108394.

 

Conte PF, Gennari A, Landucci E, et al. Role of epirubicin in advanced breast cancer. Clin Breast Cancer. 2000 Sep;1 Suppl 1:S46-51. PMID: 11970749.

" Xn Not dangerous goods.

LKT E6259 Epoxiconazole 5 g 65.6 Triazole; 14-α demethylase inhibitor, potential aromatase inhibitor. 106325-08-0 ≥95% 329.76 C17H13ClFN3O C1=CC=C(C(=C1)C2C(O2)(CN3C=NC=N3)C4=CC=C(C=C4)F)Cl Ambient Ambient "Schneider S, Hofmann T, Stinchcombe S, et al. Species differences in developmental toxicity of epoxiconazole and its relevance to humans. Birth Defects Res B Dev Reprod Toxicol. 2013 Jun;98(3):230-46. PMID: 23630118.

 

Kjærstad MB, Taxvig C, Nellemann C, et al. Endocrine disrupting effects in vitro of conazole antifungals used as pesticides and pharmaceuticals. Reprod Toxicol. 2010 Dec;30(4):573-82. PMID: 20708073.

 

Taxvig C, Vinggaard AM, Hass U, et al. Endocrine-disrupting properties in vivo of widely used azole fungicides. Int J Androl. 2008 Apr;31(2):170-7. PMID: 18067565.

 

Taxvig C, Hass U, Axelstad M, et al. Endocrine-disrupting activities in vivo of the fungicides tebuconazole and epoxiconazole. Toxicol Sci. 2007 Dec;100(2):464-73. PMID: 17785682.

" Carc., N, Repr. "UN number: 3077     Class: 9     Packing Group: III

Proper shipping name: Environmentally hazardous substance, solid, n.o.s. (Epoxiconazole)"

LKT E6259 Epoxiconazole 10 g 84.3 Triazole; 14-α demethylase inhibitor, potential aromatase inhibitor. 106325-08-0 ≥95% 329.76 C17H13ClFN3O C1=CC=C(C(=C1)C2C(O2)(CN3C=NC=N3)C4=CC=C(C=C4)F)Cl Ambient Ambient "Schneider S, Hofmann T, Stinchcombe S, et al. Species differences in developmental toxicity of epoxiconazole and its relevance to humans. Birth Defects Res B Dev Reprod Toxicol. 2013 Jun;98(3):230-46. PMID: 23630118.

 

Kjærstad MB, Taxvig C, Nellemann C, et al. Endocrine disrupting effects in vitro of conazole antifungals used as pesticides and pharmaceuticals. Reprod Toxicol. 2010 Dec;30(4):573-82. PMID: 20708073.

 

Taxvig C, Vinggaard AM, Hass U, et al. Endocrine-disrupting properties in vivo of widely used azole fungicides. Int J Androl. 2008 Apr;31(2):170-7. PMID: 18067565.

 

Taxvig C, Hass U, Axelstad M, et al. Endocrine-disrupting activities in vivo of the fungicides tebuconazole and epoxiconazole. Toxicol Sci. 2007 Dec;100(2):464-73. PMID: 17785682.

" Carc., N, Repr. "UN number: 3077     Class: 9     Packing Group: III

Proper shipping name: Environmentally hazardous substance, solid, n.o.s. (Epoxiconazole)"

LKT E6259 Epoxiconazole 100 g 497 Triazole; 14-α demethylase inhibitor, potential aromatase inhibitor. 106325-08-0 ≥95% 329.76 C17H13ClFN3O C1=CC=C(C(=C1)C2C(O2)(CN3C=NC=N3)C4=CC=C(C=C4)F)Cl Ambient Ambient "Schneider S, Hofmann T, Stinchcombe S, et al. Species differences in developmental toxicity of epoxiconazole and its relevance to humans. Birth Defects Res B Dev Reprod Toxicol. 2013 Jun;98(3):230-46. PMID: 23630118.

 

Kjærstad MB, Taxvig C, Nellemann C, et al. Endocrine disrupting effects in vitro of conazole antifungals used as pesticides and pharmaceuticals. Reprod Toxicol. 2010 Dec;30(4):573-82. PMID: 20708073.

 

Taxvig C, Vinggaard AM, Hass U, et al. Endocrine-disrupting properties in vivo of widely used azole fungicides. Int J Androl. 2008 Apr;31(2):170-7. PMID: 18067565.

 

Taxvig C, Hass U, Axelstad M, et al. Endocrine-disrupting activities in vivo of the fungicides tebuconazole and epoxiconazole. Toxicol Sci. 2007 Dec;100(2):464-73. PMID: 17785682.

" Carc., N, Repr. "UN number: 3077     Class: 9     Packing Group: III

Proper shipping name: Environmentally hazardous substance, solid, n.o.s. (Epoxiconazole)"

LKT E6376 Eptifibatide 5 mg 300.1 Glycoprotein IIb/IIIa inhibitor. "N6-(aminoiminomethyl)-N2-(3-mercapto-1-oxopropyl)-L-lysylglycyl-L-alpha-aspartyl-L-tryptophy-L-prolyl-L-Cysteinamide, cyclic (1-6)-disulfide 

" Integrilin 188627-80-7 ≥98% 832.4 C35H49N11O9S2 C1CC2C(=O)NC(CSSCCC(=O)NC(C(=O)NCC(=O)NC(C(=O)NC(C(=O)N2C1)CC3=CNC4=CC=CC=C43)CC(=O)O)CCCCN=C(N)N)C(=O)N Ambient -20°C "Angiolillo DJ. The evolution of antiplatelet therapy in the treatment of acute coronary syndromes: from aspirin to the present day. Drugs. 2012 Nov 12;72(16):2087-116. PMID: 23083110.

 

Gurbel PA, Galbut B, Bliden KP, et al. Effect of eptifibatide for acute coronary syndromes: rapid versus late administration--therapeutic yield on platelets (The EARLY Platelet Substudy). J Thromb Thrombolysis. 2002 Dec;14(3):213-9. PMID: 12913401.

" Not dangerous goods.

LKT E6376 Eptifibatide 10 mg 510 Glycoprotein IIb/IIIa inhibitor. "N6-(aminoiminomethyl)-N2-(3-mercapto-1-oxopropyl)-L-lysylglycyl-L-alpha-aspartyl-L-tryptophy-L-prolyl-L-Cysteinamide, cyclic (1-6)-disulfide 

" Integrilin 188627-80-7 ≥98% 832.4 C35H49N11O9S2 C1CC2C(=O)NC(CSSCCC(=O)NC(C(=O)NCC(=O)NC(C(=O)NC(C(=O)N2C1)CC3=CNC4=CC=CC=C43)CC(=O)O)CCCCN=C(N)N)C(=O)N Ambient -20°C "Angiolillo DJ. The evolution of antiplatelet therapy in the treatment of acute coronary syndromes: from aspirin to the present day. Drugs. 2012 Nov 12;72(16):2087-116. PMID: 23083110.

 

Gurbel PA, Galbut B, Bliden KP, et al. Effect of eptifibatide for acute coronary syndromes: rapid versus late administration--therapeutic yield on platelets (The EARLY Platelet Substudy). J Thromb Thrombolysis. 2002 Dec;14(3):213-9. PMID: 12913401.

" Not dangerous goods.

LKT E6376 Eptifibatide 25 mg 900.1 Glycoprotein IIb/IIIa inhibitor. "N6-(aminoiminomethyl)-N2-(3-mercapto-1-oxopropyl)-L-lysylglycyl-L-alpha-aspartyl-L-tryptophy-L-prolyl-L-Cysteinamide, cyclic (1-6)-disulfide 

" Integrilin 188627-80-7 ≥98% 832.4 C35H49N11O9S2 C1CC2C(=O)NC(CSSCCC(=O)NC(C(=O)NCC(=O)NC(C(=O)NC(C(=O)N2C1)CC3=CNC4=CC=CC=C43)CC(=O)O)CCCCN=C(N)N)C(=O)N Ambient -20°C "Angiolillo DJ. The evolution of antiplatelet therapy in the treatment of acute coronary syndromes: from aspirin to the present day. Drugs. 2012 Nov 12;72(16):2087-116. PMID: 23083110.

 

Gurbel PA, Galbut B, Bliden KP, et al. Effect of eptifibatide for acute coronary syndromes: rapid versus late administration--therapeutic yield on platelets (The EARLY Platelet Substudy). J Thromb Thrombolysis. 2002 Dec;14(3):213-9. PMID: 12913401.

" Not dangerous goods.

LKT E6432 (−)-Epinephrine 1 g 27.2 Active isomer of epinephrine, endogenous hormone neurotransmitter, involved in sympathetic nervous system signaling; α/β-adrenergic agonist. Bronkaid Mist; Eppy; Glauposine; Simplene; Suprarenaline 51-43-4 ≥98% 183.2 C9H13NO3 CNCC(C1=CC(=C(C=C1)O)O)O Crystals brown when exposed to light and air. Ambient 4°C Slightly soluble in water and alcohol. Soluble in aqueous solutions of mineral acids, NaOH, and KOH. Insoluble in ether, chloroform or acetone. "Seravalle G, Dimitriadis K, Dell'Oro R, et al. How to assess sympathetic nervous system activity in clinical practice. Curr Clin Pharmacol. 2013 Aug;8(3):182-8. PMID: 23173963.

 

Busse PJ, Buckland MS. Non-histaminergic angioedema: focus on bradykinin-mediated angioedema. Clin Exp Allergy. 2013 Apr;43(4):385-94. PMID: 23517034.

 

Warren JB, Pixley FJ, Dollery CT. Importance of beta 2-adrenoceptor stimulation in the suppression of intradermal antigen challenge by adrenaline. Br J Clin Pharmacol. 1989 Feb;27(2):173-7. PMID: 2565729.

 

Warren J. The adrenal medulla and the airway. Br J Dis Chest. 1986 Jan;80(1):1-6. PMID: 3004549.

 

Berecek KH, Brody MJ. Evidence for a neurotransmitter role for epinephrine derived from the adrenal medulla. Am J Physiol. 1982 Apr;242(4):H593-601. PMID: 6278965

" T "UN number: 2811     Class:  6.1     Packing group:  II

Proper shipping name:  Toxic solids, organic, n.o.s. (Epinephrine)

Reportable quantity (RQ):  1000 lbs.     Poison inhalation hazard:  No."

LKT E6432 (−)-Epinephrine 5 g 88.3 Active isomer of epinephrine, endogenous hormone neurotransmitter, involved in sympathetic nervous system signaling; α/β-adrenergic agonist. Bronkaid Mist; Eppy; Glauposine; Simplene; Suprarenaline 51-43-4 ≥98% 183.2 C9H13NO3 CNCC(C1=CC(=C(C=C1)O)O)O Crystals brown when exposed to light and air. Ambient 4°C Slightly soluble in water and alcohol. Soluble in aqueous solutions of mineral acids, NaOH, and KOH. Insoluble in ether, chloroform or acetone. "Seravalle G, Dimitriadis K, Dell'Oro R, et al. How to assess sympathetic nervous system activity in clinical practice. Curr Clin Pharmacol. 2013 Aug;8(3):182-8. PMID: 23173963.

 

Busse PJ, Buckland MS. Non-histaminergic angioedema: focus on bradykinin-mediated angioedema. Clin Exp Allergy. 2013 Apr;43(4):385-94. PMID: 23517034.

 

Warren JB, Pixley FJ, Dollery CT. Importance of beta 2-adrenoceptor stimulation in the suppression of intradermal antigen challenge by adrenaline. Br J Clin Pharmacol. 1989 Feb;27(2):173-7. PMID: 2565729.

 

Warren J. The adrenal medulla and the airway. Br J Dis Chest. 1986 Jan;80(1):1-6. PMID: 3004549.

 

Berecek KH, Brody MJ. Evidence for a neurotransmitter role for epinephrine derived from the adrenal medulla. Am J Physiol. 1982 Apr;242(4):H593-601. PMID: 6278965

" T "UN number: 2811     Class:  6.1     Packing group:  II

Proper shipping name:  Toxic solids, organic, n.o.s. (Epinephrine)

Reportable quantity (RQ):  1000 lbs.     Poison inhalation hazard:  No."

LKT E6432 (−)-Epinephrine 10 g 156.2 Active isomer of epinephrine, endogenous hormone neurotransmitter, involved in sympathetic nervous system signaling; α/β-adrenergic agonist. Bronkaid Mist; Eppy; Glauposine; Simplene; Suprarenaline 51-43-4 ≥98% 183.2 C9H13NO3 CNCC(C1=CC(=C(C=C1)O)O)O Crystals brown when exposed to light and air. Ambient 4°C Slightly soluble in water and alcohol. Soluble in aqueous solutions of mineral acids, NaOH, and KOH. Insoluble in ether, chloroform or acetone. "Seravalle G, Dimitriadis K, Dell'Oro R, et al. How to assess sympathetic nervous system activity in clinical practice. Curr Clin Pharmacol. 2013 Aug;8(3):182-8. PMID: 23173963.

 

Busse PJ, Buckland MS. Non-histaminergic angioedema: focus on bradykinin-mediated angioedema. Clin Exp Allergy. 2013 Apr;43(4):385-94. PMID: 23517034.

 

Warren JB, Pixley FJ, Dollery CT. Importance of beta 2-adrenoceptor stimulation in the suppression of intradermal antigen challenge by adrenaline. Br J Clin Pharmacol. 1989 Feb;27(2):173-7. PMID: 2565729.

 

Warren J. The adrenal medulla and the airway. Br J Dis Chest. 1986 Jan;80(1):1-6. PMID: 3004549.

 

Berecek KH, Brody MJ. Evidence for a neurotransmitter role for epinephrine derived from the adrenal medulla. Am J Physiol. 1982 Apr;242(4):H593-601. PMID: 6278965

" T "UN number: 2811     Class:  6.1     Packing group:  II

Proper shipping name:  Toxic solids, organic, n.o.s. (Epinephrine)

Reportable quantity (RQ):  1000 lbs.     Poison inhalation hazard:  No."

LKT E6470 Eprinomectin 100 mg 125.9 Semi-synthetic avermectin; GABA potentiator. (4''R)-4''-(Acetylamino)-4''-deoxy-avermectin B1 Eprinex 123997-26-2 ≥45% B1a: R=C2H5 C50H75NO14; B1b: R=CH3 C49H73NO14 CC1C=CC=C2COC3C2(C(C=C(C3O)C)C(=O)OC4CC(CC=C(C1OC5CC(C(C(O5)C)OC6CC(C(C(O6)C)NC(=O)C)OC)OC)C)OC7(C4)C=CC(C(O7)C(C)C)C)O Ambient Ambient Soluble in methanol. "Knaus M, Chester ST, Rosentel J, et al. Efficacy of a novel topical combination of fipronil, (S)-methoprene, eprinomectin and praziquantel against larval and adult stages of the cat lungworm, Aelurostrongylus abstrusus. Vet Parasitol. 2014 Apr 28;202(1-2):64-8. PMID: 24703080.

 

Nazir T, Katoch R, Godara R, et al. Efficacy of eprinomectin pour-on against Rhipicephalus (Boophilus) microplus on buffaloes. J Parasit Dis. 2013 Oct;37(2):166-7. PMID: 24431562.

" T, N "UN number: 2811     Class: 6.1     Packing Group: III

Proper shipping name: Toxic solid, organic, n.o.s. (Eprinomectin)"

LKT E6470 Eprinomectin 250 mg 209.8 Semi-synthetic avermectin; GABA potentiator. (4''R)-4''-(Acetylamino)-4''-deoxy-avermectin B1 Eprinex 123997-26-2 ≥45% B1a: R=C2H5 C50H75NO14; B1b: R=CH3 C49H73NO14 CC1C=CC=C2COC3C2(C(C=C(C3O)C)C(=O)OC4CC(CC=C(C1OC5CC(C(C(O5)C)OC6CC(C(C(O6)C)NC(=O)C)OC)OC)C)OC7(C4)C=CC(C(O7)C(C)C)C)O Ambient Ambient Soluble in methanol. "Knaus M, Chester ST, Rosentel J, et al. Efficacy of a novel topical combination of fipronil, (S)-methoprene, eprinomectin and praziquantel against larval and adult stages of the cat lungworm, Aelurostrongylus abstrusus. Vet Parasitol. 2014 Apr 28;202(1-2):64-8. PMID: 24703080.

 

Nazir T, Katoch R, Godara R, et al. Efficacy of eprinomectin pour-on against Rhipicephalus (Boophilus) microplus on buffaloes. J Parasit Dis. 2013 Oct;37(2):166-7. PMID: 24431562.

" T, N "UN number: 2811     Class: 6.1     Packing Group: III

Proper shipping name: Toxic solid, organic, n.o.s. (Eprinomectin)"

LKT E6470 Eprinomectin 1 g 672.2 Semi-synthetic avermectin; GABA potentiator. (4''R)-4''-(Acetylamino)-4''-deoxy-avermectin B1 Eprinex 123997-26-2 ≥45% B1a: R=C2H5 C50H75NO14; B1b: R=CH3 C49H73NO14 CC1C=CC=C2COC3C2(C(C=C(C3O)C)C(=O)OC4CC(CC=C(C1OC5CC(C(C(O5)C)OC6CC(C(C(O6)C)NC(=O)C)OC)OC)C)OC7(C4)C=CC(C(O7)C(C)C)C)O Ambient Ambient Soluble in methanol. "Knaus M, Chester ST, Rosentel J, et al. Efficacy of a novel topical combination of fipronil, (S)-methoprene, eprinomectin and praziquantel against larval and adult stages of the cat lungworm, Aelurostrongylus abstrusus. Vet Parasitol. 2014 Apr 28;202(1-2):64-8. PMID: 24703080.

 

Nazir T, Katoch R, Godara R, et al. Efficacy of eprinomectin pour-on against Rhipicephalus (Boophilus) microplus on buffaloes. J Parasit Dis. 2013 Oct;37(2):166-7. PMID: 24431562.

" T, N "UN number: 2811     Class: 6.1     Packing Group: III

Proper shipping name: Toxic solid, organic, n.o.s. (Eprinomectin)"

LKT E6781 (±)-Equol 10 mg 121.9 Isoflavone, phytoestrogen found in soy; ER agonist. (R,S)-Equol; 3,4-Dihydro-3,(4-hydroxyphenyl)-2H-1-benzopyran-7-ol; 4',7-Dihydroxyisoflavane 94105-90-5 ≥98% 242.27 C15H14O3 C1C(COC2=C1C=CC(=C2)O)C3=CC=C(C=C3)O Ambient -20°C Soluble in DMSO, ethanol, dilute aqueous base.  Insoluble in water. "Lephart ED. Protective effects of equol and their polyphenolic isomers against dermal aging: microarray/protein evidence with clinical implications and unique delivery into human skin. Pharm Biol. 2013 Nov;51(11):1393-400. PMID: 23862588.

 

Richardson TE, Simpkins JW. R- and S-equol have equivalent cytoprotective effects in Friedreich's ataxia. BMC Pharmacol Toxicol. 2012 Oct 22;13:12. PMID: 23088310.

 

Choi EJ, Kim GH. Anticancer mechanism of equol in 7,12-dimethylbenz(a)anthracene-treated animals. Int J Oncol. 2011 Sep;39(3):747-54. PMID: 21667019.

 

Muñoz Y, Garrido A, Valladares L. Equol is more active than soy isoflavone itself to compete for binding to thromboxane A(2) receptor in human platelets. Thromb Res. 2009 Mar;123(5):740-4. PMID: 18786699.

 

Kang JS, Yoon YD, Han MH, et al. Estrogen receptor-independent inhibition of tumor necrosis factor-alpha gene expression by phytoestrogen equol is mediated by blocking nuclear factor-kappaB activation in mouse macrophages. Biochem Pharmacol. 2005 Dec 19;71(1-2):136-43. PMID: 16288994.

" Not dangerous goods.

LKT E6781 (±)-Equol 25 mg 234.5 Isoflavone, phytoestrogen found in soy; ER agonist. (R,S)-Equol; 3,4-Dihydro-3,(4-hydroxyphenyl)-2H-1-benzopyran-7-ol; 4',7-Dihydroxyisoflavane 94105-90-5 ≥98% 242.27 C15H14O3 C1C(COC2=C1C=CC(=C2)O)C3=CC=C(C=C3)O Ambient -20°C Soluble in DMSO, ethanol, dilute aqueous base.  Insoluble in water. "Lephart ED. Protective effects of equol and their polyphenolic isomers against dermal aging: microarray/protein evidence with clinical implications and unique delivery into human skin. Pharm Biol. 2013 Nov;51(11):1393-400. PMID: 23862588.

 

Richardson TE, Simpkins JW. R- and S-equol have equivalent cytoprotective effects in Friedreich's ataxia. BMC Pharmacol Toxicol. 2012 Oct 22;13:12. PMID: 23088310.

 

Choi EJ, Kim GH. Anticancer mechanism of equol in 7,12-dimethylbenz(a)anthracene-treated animals. Int J Oncol. 2011 Sep;39(3):747-54. PMID: 21667019.

 

Muñoz Y, Garrido A, Valladares L. Equol is more active than soy isoflavone itself to compete for binding to thromboxane A(2) receptor in human platelets. Thromb Res. 2009 Mar;123(5):740-4. PMID: 18786699.

 

Kang JS, Yoon YD, Han MH, et al. Estrogen receptor-independent inhibition of tumor necrosis factor-alpha gene expression by phytoestrogen equol is mediated by blocking nuclear factor-kappaB activation in mouse macrophages. Biochem Pharmacol. 2005 Dec 19;71(1-2):136-43. PMID: 16288994.

" Not dangerous goods.

LKT E6781 (±)-Equol 100 mg 609.5 Isoflavone, phytoestrogen found in soy; ER agonist. (R,S)-Equol; 3,4-Dihydro-3,(4-hydroxyphenyl)-2H-1-benzopyran-7-ol; 4',7-Dihydroxyisoflavane 94105-90-5 ≥98% 242.27 C15H14O3 C1C(COC2=C1C=CC(=C2)O)C3=CC=C(C=C3)O Ambient -20°C Soluble in DMSO, ethanol, dilute aqueous base.  Insoluble in water. "Lephart ED. Protective effects of equol and their polyphenolic isomers against dermal aging: microarray/protein evidence with clinical implications and unique delivery into human skin. Pharm Biol. 2013 Nov;51(11):1393-400. PMID: 23862588.

 

Richardson TE, Simpkins JW. R- and S-equol have equivalent cytoprotective effects in Friedreich's ataxia. BMC Pharmacol Toxicol. 2012 Oct 22;13:12. PMID: 23088310.

 

Choi EJ, Kim GH. Anticancer mechanism of equol in 7,12-dimethylbenz(a)anthracene-treated animals. Int J Oncol. 2011 Sep;39(3):747-54. PMID: 21667019.

 

Muñoz Y, Garrido A, Valladares L. Equol is more active than soy isoflavone itself to compete for binding to thromboxane A(2) receptor in human platelets. Thromb Res. 2009 Mar;123(5):740-4. PMID: 18786699.

 

Kang JS, Yoon YD, Han MH, et al. Estrogen receptor-independent inhibition of tumor necrosis factor-alpha gene expression by phytoestrogen equol is mediated by blocking nuclear factor-kappaB activation in mouse macrophages. Biochem Pharmacol. 2005 Dec 19;71(1-2):136-43. PMID: 16288994.

" Not dangerous goods.

LKT E6814 Erdosteine 100 mg 54.4 Thiol derivative, antioxidant. [[2-Oxo-2-[(tetrahydro-2-oxo-3-thienyl)amino]ethyl]- thio]acetic acid RV-144; Secresolv 84611-23-4 ≥98% 249.31 C8H11NO4S2 C1CSC(=O)C1NC(=O)CSCC(=O)O Ambient Ambient Slightly soluble in water, methanol or ethanol. "Marabini L, Calò R, Braga PC. Protective effect of erdosteine metabolite I against hydrogen peroxide-induced oxidative DNA-damage in lung epithelial cells. Arzneimittelforschung. 2011;61(12):700-6. PMID: 22282957.

 

Dal Negro RW, Visconti M, Tognella S, et al. Erdosteine affects eicosanoid production in COPD. Int J Clin Pharmacol Ther. 2011 Jan;49(1):41-5. PMID: 21176724.

" Not dangerous goods.

LKT E6814 Erdosteine 500 mg 163.2 Thiol derivative, antioxidant. [[2-Oxo-2-[(tetrahydro-2-oxo-3-thienyl)amino]ethyl]- thio]acetic acid RV-144; Secresolv 84611-23-4 ≥98% 249.31 C8H11NO4S2 C1CSC(=O)C1NC(=O)CSCC(=O)O Ambient Ambient Slightly soluble in water, methanol or ethanol. "Marabini L, Calò R, Braga PC. Protective effect of erdosteine metabolite I against hydrogen peroxide-induced oxidative DNA-damage in lung epithelial cells. Arzneimittelforschung. 2011;61(12):700-6. PMID: 22282957.

 

Dal Negro RW, Visconti M, Tognella S, et al. Erdosteine affects eicosanoid production in COPD. Int J Clin Pharmacol Ther. 2011 Jan;49(1):41-5. PMID: 21176724.

" Not dangerous goods.

LKT E6814 Erdosteine 1 g 271.7 Thiol derivative, antioxidant. [[2-Oxo-2-[(tetrahydro-2-oxo-3-thienyl)amino]ethyl]- thio]acetic acid RV-144; Secresolv 84611-23-4 ≥98% 249.31 C8H11NO4S2 C1CSC(=O)C1NC(=O)CSCC(=O)O Ambient Ambient Slightly soluble in water, methanol or ethanol. "Marabini L, Calò R, Braga PC. Protective effect of erdosteine metabolite I against hydrogen peroxide-induced oxidative DNA-damage in lung epithelial cells. Arzneimittelforschung. 2011;61(12):700-6. PMID: 22282957.

 

Dal Negro RW, Visconti M, Tognella S, et al. Erdosteine affects eicosanoid production in COPD. Int J Clin Pharmacol Ther. 2011 Jan;49(1):41-5. PMID: 21176724.

" Not dangerous goods.

LKT E6825 Ergosterol 5 g 73.5 Sterol cell membrane component found in yeast and fungi. "(3β,5α)-Ergostan-3-ol

" Ergosterin, Provitamin D2. 57-87-4 ≥96% 396.65 C28H44O CC(C)C(C)C=CC(C)C1CCC2C1(CCC3C2=CC=C4C3(CCC(C4)O)C)C Protect from light and air. Ambient 4°C Practically insoluble in water. Soluble in chloroform, boiling ether, boiling alcohol. "Roberts CW, McLeod R, Rice DW, et al. Fatty acid and sterol metabolism: potential antimicrobial targets in apicomplexan and trypanosomatid parasitic protozoa. Mol Biochem Parasitol. 2003 Feb;126(2):129-42. PMID: 12615312.

 

Takaku T, Kimura Y, Okuda H. Isolation of an antitumor compound from Agaricus blazei Murill and its mechanism of action. J Nutr. 2001 May;131(5):1409-13. PMID: 11340091.

 

Yazawa Y, Yokota M, Sugiyama K. Antitumor promoting effect of an active component of Polyporus, ergosterol and related compounds on rat urinary bladder carcinogenesis in a short-term test with concanavalin A. Biol Pharm Bull. 2000 Nov;23(11):1298-302. PMID: 11085355.

" None Not dangerous goods.

LKT E6825 Ergosterol 10 g 125.9 Sterol cell membrane component found in yeast and fungi. "(3β,5α)-Ergostan-3-ol

" Ergosterin, Provitamin D2. 57-87-4 ≥96% 396.65 C28H44O CC(C)C(C)C=CC(C)C1CCC2C1(CCC3C2=CC=C4C3(CCC(C4)O)C)C Protect from light and air. Ambient 4°C Practically insoluble in water. Soluble in chloroform, boiling ether, boiling alcohol. "Roberts CW, McLeod R, Rice DW, et al. Fatty acid and sterol metabolism: potential antimicrobial targets in apicomplexan and trypanosomatid parasitic protozoa. Mol Biochem Parasitol. 2003 Feb;126(2):129-42. PMID: 12615312.

 

Takaku T, Kimura Y, Okuda H. Isolation of an antitumor compound from Agaricus blazei Murill and its mechanism of action. J Nutr. 2001 May;131(5):1409-13. PMID: 11340091.

 

Yazawa Y, Yokota M, Sugiyama K. Antitumor promoting effect of an active component of Polyporus, ergosterol and related compounds on rat urinary bladder carcinogenesis in a short-term test with concanavalin A. Biol Pharm Bull. 2000 Nov;23(11):1298-302. PMID: 11085355.

" None Not dangerous goods.

LKT E6825 Ergosterol 25 g 252.1 Sterol cell membrane component found in yeast and fungi. "(3β,5α)-Ergostan-3-ol

" Ergosterin, Provitamin D2. 57-87-4 ≥96% 396.65 C28H44O CC(C)C(C)C=CC(C)C1CCC2C1(CCC3C2=CC=C4C3(CCC(C4)O)C)C Protect from light and air. Ambient 4°C Practically insoluble in water. Soluble in chloroform, boiling ether, boiling alcohol. "Roberts CW, McLeod R, Rice DW, et al. Fatty acid and sterol metabolism: potential antimicrobial targets in apicomplexan and trypanosomatid parasitic protozoa. Mol Biochem Parasitol. 2003 Feb;126(2):129-42. PMID: 12615312.

 

Takaku T, Kimura Y, Okuda H. Isolation of an antitumor compound from Agaricus blazei Murill and its mechanism of action. J Nutr. 2001 May;131(5):1409-13. PMID: 11340091.

 

Yazawa Y, Yokota M, Sugiyama K. Antitumor promoting effect of an active component of Polyporus, ergosterol and related compounds on rat urinary bladder carcinogenesis in a short-term test with concanavalin A. Biol Pharm Bull. 2000 Nov;23(11):1298-302. PMID: 11085355.

" None Not dangerous goods.

LKT E6825 Ergosterol 100 g 829.7 Sterol cell membrane component found in yeast and fungi. "(3β,5α)-Ergostan-3-ol

" Ergosterin, Provitamin D2. 57-87-4 ≥96% 396.65 C28H44O CC(C)C(C)C=CC(C)C1CCC2C1(CCC3C2=CC=C4C3(CCC(C4)O)C)C Protect from light and air. Ambient 4°C Practically insoluble in water. Soluble in chloroform, boiling ether, boiling alcohol. "Roberts CW, McLeod R, Rice DW, et al. Fatty acid and sterol metabolism: potential antimicrobial targets in apicomplexan and trypanosomatid parasitic protozoa. Mol Biochem Parasitol. 2003 Feb;126(2):129-42. PMID: 12615312.

 

Takaku T, Kimura Y, Okuda H. Isolation of an antitumor compound from Agaricus blazei Murill and its mechanism of action. J Nutr. 2001 May;131(5):1409-13. PMID: 11340091.

 

Yazawa Y, Yokota M, Sugiyama K. Antitumor promoting effect of an active component of Polyporus, ergosterol and related compounds on rat urinary bladder carcinogenesis in a short-term test with concanavalin A. Biol Pharm Bull. 2000 Nov;23(11):1298-302. PMID: 11085355.

" None Not dangerous goods.

LKT E6846 Erlotinib Hydrochloride 10 mg 54.4 EGFR inhibitor. 183319-69-9 ≥98% 429.9 C22H23N3O4 HCl COCCOC1=C(C=C2C(=C1)C(=NC=N2)NC3=CC=CC(=C3)C#C)OCCOC.Cl Ambient Ambient DMSO (16 mg/mL) H2O "Li YY, Lam SK, Mak JC, et al. Erlotinib-induced autophagy in epidermal growth factor receptor mutated non-small cell lung cancer. Lung Cancer. 2013 Sep;81(3):354-61. PMID: 23769318.

 

Miyabayashi K, Ijichi H, Mohri D, et al. Erlotinib prolongs survival in pancreatic cancer by blocking gemcitabine-induced MAPK signals. Cancer Res. 2013 Apr 1;73(7):2221-34. PMID: 23378339.

 

Weickhardt AJ, Price TJ, Chong G, et al. Dual targeting of the epidermal growth factor receptor using the combination of cetuximab and erlotinib: preclinical evaluation and results of the phase II DUX study in chemotherapy-refractory, advanced colorectal cancer. J Clin Oncol. 2012 May 1;30(13):1505-12. PMID: 22412142.

 

Zerbe LK, Dwyer-Nield LD, Fritz JM, et al. Inhibition by erlotinib of primary lung adenocarcinoma at an early stage in male mice. Cancer Chemother Pharmacol. 2008 Sep;62(4):605-20. PMID: 18030469.

 

Ling YH, Li T, Yuan Z, et al. Erlotinib, an effective epidermal growth factor receptor tyrosine kinase inhibitor, induces p27KIP1 up-regulation and nuclear translocation in association with cell growth inhibition and G1/S phase arrest in human non-small-cell lung cancer cell lines. Mol Pharmacol. 2007 Aug;72(2):248-58. PMID: 17456787.

" Xn, Carc. Cat. 3, Repr. Cat. 3, N "UN number: 2811     Class: 6.1     Packing Group: III

Proper shipping name: Toxic solid, organic, n.o.s. (Erlotinib hydrochloride)"

LKT E6846 Erlotinib Hydrochloride 100 mg 197.1 EGFR inhibitor. 183319-69-9 ≥98% 429.9 C22H23N3O4 HCl COCCOC1=C(C=C2C(=C1)C(=NC=N2)NC3=CC=CC(=C3)C#C)OCCOC.Cl Ambient Ambient DMSO (16 mg/mL) H2O "Li YY, Lam SK, Mak JC, et al. Erlotinib-induced autophagy in epidermal growth factor receptor mutated non-small cell lung cancer. Lung Cancer. 2013 Sep;81(3):354-61. PMID: 23769318.

 

Miyabayashi K, Ijichi H, Mohri D, et al. Erlotinib prolongs survival in pancreatic cancer by blocking gemcitabine-induced MAPK signals. Cancer Res. 2013 Apr 1;73(7):2221-34. PMID: 23378339.

 

Weickhardt AJ, Price TJ, Chong G, et al. Dual targeting of the epidermal growth factor receptor using the combination of cetuximab and erlotinib: preclinical evaluation and results of the phase II DUX study in chemotherapy-refractory, advanced colorectal cancer. J Clin Oncol. 2012 May 1;30(13):1505-12. PMID: 22412142.

 

Zerbe LK, Dwyer-Nield LD, Fritz JM, et al. Inhibition by erlotinib of primary lung adenocarcinoma at an early stage in male mice. Cancer Chemother Pharmacol. 2008 Sep;62(4):605-20. PMID: 18030469.

 

Ling YH, Li T, Yuan Z, et al. Erlotinib, an effective epidermal growth factor receptor tyrosine kinase inhibitor, induces p27KIP1 up-regulation and nuclear translocation in association with cell growth inhibition and G1/S phase arrest in human non-small-cell lung cancer cell lines. Mol Pharmacol. 2007 Aug;72(2):248-58. PMID: 17456787.

" Xn, Carc. Cat. 3, Repr. Cat. 3, N "UN number: 2811     Class: 6.1     Packing Group: III

Proper shipping name: Toxic solid, organic, n.o.s. (Erlotinib hydrochloride)"

LKT E6846 Erlotinib Hydrochloride 25 mg 115.5 EGFR inhibitor. 183319-69-9 ≥98% 429.9 C22H23N3O4 HCl COCCOC1=C(C=C2C(=C1)C(=NC=N2)NC3=CC=CC(=C3)C#C)OCCOC.Cl Ambient Ambient DMSO (16 mg/mL) H2O "Li YY, Lam SK, Mak JC, et al. Erlotinib-induced autophagy in epidermal growth factor receptor mutated non-small cell lung cancer. Lung Cancer. 2013 Sep;81(3):354-61. PMID: 23769318.

 

Miyabayashi K, Ijichi H, Mohri D, et al. Erlotinib prolongs survival in pancreatic cancer by blocking gemcitabine-induced MAPK signals. Cancer Res. 2013 Apr 1;73(7):2221-34. PMID: 23378339.

 

Weickhardt AJ, Price TJ, Chong G, et al. Dual targeting of the epidermal growth factor receptor using the combination of cetuximab and erlotinib: preclinical evaluation and results of the phase II DUX study in chemotherapy-refractory, advanced colorectal cancer. J Clin Oncol. 2012 May 1;30(13):1505-12. PMID: 22412142.

 

Zerbe LK, Dwyer-Nield LD, Fritz JM, et al. Inhibition by erlotinib of primary lung adenocarcinoma at an early stage in male mice. Cancer Chemother Pharmacol. 2008 Sep;62(4):605-20. PMID: 18030469.

 

Ling YH, Li T, Yuan Z, et al. Erlotinib, an effective epidermal growth factor receptor tyrosine kinase inhibitor, induces p27KIP1 up-regulation and nuclear translocation in association with cell growth inhibition and G1/S phase arrest in human non-small-cell lung cancer cell lines. Mol Pharmacol. 2007 Aug;72(2):248-58. PMID: 17456787.

" Xn, Carc. Cat. 3, Repr. Cat. 3, N "UN number: 2811     Class: 6.1     Packing Group: III

Proper shipping name: Toxic solid, organic, n.o.s. (Erlotinib hydrochloride)"

LKT E6993 Erythromycin Resistance Peptide MRLFV 1 mg 63 Peptide, confers resistance against macrolide antibiotics by preventing antibiotic-ribosome interactions. E-peptide ≥95% 664.86 C31H52N8O6S Ambient -20°C Verdier L, Gharbi-Benarous J, Bertho G, et al.  Antibiotic resistance peptides: interaction of peptides conferring macrolide and ketolide resistance with Staphylococcus aureus ribosomes: conformation of bound peptides as determined by transferred NOE experiments. Biochemistry. 2002 Apr 2;41(13):4218-29. PMID: 11914067.

LKT E6993 Erythromycin Resistance Peptide MRLFV 2 mg 104.9 Peptide, confers resistance against macrolide antibiotics by preventing antibiotic-ribosome interactions. E-peptide ≥95% 664.86 C31H52N8O6S Ambient -20°C Verdier L, Gharbi-Benarous J, Bertho G, et al.  Antibiotic resistance peptides: interaction of peptides conferring macrolide and ketolide resistance with Staphylococcus aureus ribosomes: conformation of bound peptides as determined by transferred NOE experiments. Biochemistry. 2002 Apr 2;41(13):4218-29. PMID: 11914067.

LKT E6993 Erythromycin Resistance Peptide MRLFV 5 mg 186 Peptide, confers resistance against macrolide antibiotics by preventing antibiotic-ribosome interactions. E-peptide ≥95% 664.86 C31H52N8O6S Ambient -20°C Verdier L, Gharbi-Benarous J, Bertho G, et al.  Antibiotic resistance peptides: interaction of peptides conferring macrolide and ketolide resistance with Staphylococcus aureus ribosomes: conformation of bound peptides as determined by transferred NOE experiments. Biochemistry. 2002 Apr 2;41(13):4218-29. PMID: 11914067.

LKT E6994 Erythromycin 5 g 47.6 Macrolide; protein translation inhibitor, mammalian mRNA splicing inhibitor. "Erythromycin A

" Abomacetin; Aknin; EMU; E-Mycin; Erymax; Erycen; Erycin. 114-07-8 ≥94% 733.93 C37H67NO13 CCC1C(C(C(C(=O)C(CC(C(C(C(C(C(=O)O1)C)OC2CC(C(C(O2)C)O)(C)OC)C)OC3C(C(CC(O3)C)N(C)C)O)(C)O)C)C)O)(C)O Ambient Ambient Very slightly soluble in water (~2 mg/ml). Freely soluble in alcohols, acetone, ethyl acetate, acetonitrile or chloroform. "Hertweck M, Hiller R, Mueller MW. Inhibition of nuclear pre-mRNA splicing by antibiotics in vitro. Eur J Biochem. 2002 Jan;269(1):175-83. PMID: 11784311.

 

Menninger JR, Otto DP. Erythromycin, carbomycin, and spiramycin inhibit protein synthesis by stimulating the dissociation of peptidyl-tRNA from ribosomes. Antimicrob Agents Chemother. 1982 May;21(5):811-8. PMID: 6179465." None Not dangerous goods.

LKT E6994 Erythromycin 25 g 136 Macrolide; protein translation inhibitor, mammalian mRNA splicing inhibitor. "Erythromycin A

" Abomacetin; Aknin; EMU; E-Mycin; Erymax; Erycen; Erycin. 114-07-8 ≥94% 733.93 C37H67NO13 CCC1C(C(C(C(=O)C(CC(C(C(C(C(C(=O)O1)C)OC2CC(C(C(O2)C)O)(C)OC)C)OC3C(C(CC(O3)C)N(C)C)O)(C)O)C)C)O)(C)O Ambient Ambient Very slightly soluble in water (~2 mg/ml). Freely soluble in alcohols, acetone, ethyl acetate, acetonitrile or chloroform. "Hertweck M, Hiller R, Mueller MW. Inhibition of nuclear pre-mRNA splicing by antibiotics in vitro. Eur J Biochem. 2002 Jan;269(1):175-83. PMID: 11784311.

 

Menninger JR, Otto DP. Erythromycin, carbomycin, and spiramycin inhibit protein synthesis by stimulating the dissociation of peptidyl-tRNA from ribosomes. Antimicrob Agents Chemother. 1982 May;21(5):811-8. PMID: 6179465." None Not dangerous goods.

LKT E6994 Erythromycin 100 g 434.9 Macrolide; protein translation inhibitor, mammalian mRNA splicing inhibitor. "Erythromycin A

" Abomacetin; Aknin; EMU; E-Mycin; Erymax; Erycen; Erycin. 114-07-8 ≥94% 733.93 C37H67NO13 CCC1C(C(C(C(=O)C(CC(C(C(C(C(C(=O)O1)C)OC2CC(C(C(O2)C)O)(C)OC)C)OC3C(C(CC(O3)C)N(C)C)O)(C)O)C)C)O)(C)O Ambient Ambient Very slightly soluble in water (~2 mg/ml). Freely soluble in alcohols, acetone, ethyl acetate, acetonitrile or chloroform. "Hertweck M, Hiller R, Mueller MW. Inhibition of nuclear pre-mRNA splicing by antibiotics in vitro. Eur J Biochem. 2002 Jan;269(1):175-83. PMID: 11784311.

 

Menninger JR, Otto DP. Erythromycin, carbomycin, and spiramycin inhibit protein synthesis by stimulating the dissociation of peptidyl-tRNA from ribosomes. Antimicrob Agents Chemother. 1982 May;21(5):811-8. PMID: 6179465." None Not dangerous goods.

LKT E6995 Erythromycin Ethylsuccinate 5 g 47.6 Macrolide; protein translation inhibitor, mammalian mRNA splicing inhibitor. Anamycin E.E.S.; Arpimycin; Durapaediat; E-Mycin E; Eryliquid; Eryped. 41342-53-4 ≥97% 862.05 C43H75NO16 CCC1C(C(C(C(=O)C(CC(C(C(C(C(C(=O)O1)C)OC2CC(C(C(O2)C)O)(C)OC)C)OC3C(C(CC(O3)C)N(C)C)OC(=O)CCC(=O)OCC)(C)O)C)C)O)(C)O Ambient Ambient Very slightly soluble in water. Soluble in acetone (500 mg/L), methanol (250 mg/mL), or ethanol (110 mg/mL). "Hertweck M, Hiller R, Mueller MW. Inhibition of nuclear pre-mRNA splicing by antibiotics in vitro. Eur J Biochem. 2002 Jan;269(1):175-83. PMID: 11784311.

 

Menninger JR, Otto DP. Erythromycin, carbomycin, and spiramycin inhibit protein synthesis by stimulating the dissociation of peptidyl-tRNA from ribosomes. Antimicrob Agents Chemother. 1982 May;21(5):811-8. PMID: 6179465." Xi Not dangerous goods.

LKT E6995 Erythromycin Ethylsuccinate 25 g 136 Macrolide; protein translation inhibitor, mammalian mRNA splicing inhibitor. Anamycin E.E.S.; Arpimycin; Durapaediat; E-Mycin E; Eryliquid; Eryped. 41342-53-4 ≥97% 862.05 C43H75NO16 CCC1C(C(C(C(=O)C(CC(C(C(C(C(C(=O)O1)C)OC2CC(C(C(O2)C)O)(C)OC)C)OC3C(C(CC(O3)C)N(C)C)OC(=O)CCC(=O)OCC)(C)O)C)C)O)(C)O Ambient Ambient Very slightly soluble in water. Soluble in acetone (500 mg/L), methanol (250 mg/mL), or ethanol (110 mg/mL). "Hertweck M, Hiller R, Mueller MW. Inhibition of nuclear pre-mRNA splicing by antibiotics in vitro. Eur J Biochem. 2002 Jan;269(1):175-83. PMID: 11784311.

 

Menninger JR, Otto DP. Erythromycin, carbomycin, and spiramycin inhibit protein synthesis by stimulating the dissociation of peptidyl-tRNA from ribosomes. Antimicrob Agents Chemother. 1982 May;21(5):811-8. PMID: 6179465." Xi Not dangerous goods.

LKT E6995 Erythromycin Ethylsuccinate 100 g 434.9 Macrolide; protein translation inhibitor, mammalian mRNA splicing inhibitor. Anamycin E.E.S.; Arpimycin; Durapaediat; E-Mycin E; Eryliquid; Eryped. 41342-53-4 ≥97% 862.05 C43H75NO16 CCC1C(C(C(C(=O)C(CC(C(C(C(C(C(=O)O1)C)OC2CC(C(C(O2)C)O)(C)OC)C)OC3C(C(CC(O3)C)N(C)C)OC(=O)CCC(=O)OCC)(C)O)C)C)O)(C)O Ambient Ambient Very slightly soluble in water. Soluble in acetone (500 mg/L), methanol (250 mg/mL), or ethanol (110 mg/mL). "Hertweck M, Hiller R, Mueller MW. Inhibition of nuclear pre-mRNA splicing by antibiotics in vitro. Eur J Biochem. 2002 Jan;269(1):175-83. PMID: 11784311.

 

Menninger JR, Otto DP. Erythromycin, carbomycin, and spiramycin inhibit protein synthesis by stimulating the dissociation of peptidyl-tRNA from ribosomes. Antimicrob Agents Chemother. 1982 May;21(5):811-8. PMID: 6179465." Xi Not dangerous goods.

LKT E6996 Erythromycin Thiocyanate 25 g 150.4 Macrolide; protein translation inhibitor, mammalian mRNA splicing inhibitor. 7704-67-8 ≥90% 793.02 C37H67NO13 HSCN CCC1C(C(C(C(=O)C(CC(C(C(C(C(C(=O)O1)C)OC2CC(C(C(O2)C)O)(C)OC)C)OC3C(C(CC(O3)C)N(C)C)O)(C)O)C)C)O)(C)O.C(#N)S Ambient Ambient Soluble in alcohol. "Hertweck M, Hiller R, Mueller MW. Inhibition of nuclear pre-mRNA splicing by antibiotics in vitro. Eur J Biochem. 2002 Jan;269(1):175-83. PMID: 11784311.

 

Menninger JR, Otto DP. Erythromycin, carbomycin, and spiramycin inhibit protein synthesis by stimulating the dissociation of peptidyl-tRNA from ribosomes. Antimicrob Agents Chemother. 1982 May;21(5):811-8. PMID: 6179465." Not dangerous goods.

LKT E6996 Erythromycin Thiocyanate 100 g 461.1 Macrolide; protein translation inhibitor, mammalian mRNA splicing inhibitor. 7704-67-8 ≥90% 793.02 C37H67NO13 HSCN CCC1C(C(C(C(=O)C(CC(C(C(C(C(C(=O)O1)C)OC2CC(C(C(O2)C)O)(C)OC)C)OC3C(C(CC(O3)C)N(C)C)O)(C)O)C)C)O)(C)O.C(#N)S Ambient Ambient Soluble in alcohol. "Hertweck M, Hiller R, Mueller MW. Inhibition of nuclear pre-mRNA splicing by antibiotics in vitro. Eur J Biochem. 2002 Jan;269(1):175-83. PMID: 11784311.

 

Menninger JR, Otto DP. Erythromycin, carbomycin, and spiramycin inhibit protein synthesis by stimulating the dissociation of peptidyl-tRNA from ribosomes. Antimicrob Agents Chemother. 1982 May;21(5):811-8. PMID: 6179465." Not dangerous goods.

LKT E6997 Erythropoietin 50 U 963.7 Endogenous glycoprotein hormone involved in red blood cell production; EpoR agonist. Erythropoiesis stimulating factor; Hemopoietine; ESF; Epo 11096-26-7 ≥97% Dry Ice -80°C Soluble in water. "Liu S, Ren J, Hong Z, et al. Efficacy of erythropoietin combined with enteral nutrition for the treatment of anemia in Crohn's disease: a prospective cohort study. Nutr Clin Pract. 2013 Feb;28(1):120-7. PMID: 23064018.

 

Ashby DR, Gale DP, Busbridge M, et al. Erythropoietin administration in humans causes a marked and prolonged reduction in circulating hepcidin. Haematologica. 2010 Mar;95(3):505-8. PMID: 19833632.

 

Miskowiak K, Inkster B, Selvaraj S, et al. Erythropoietin improves mood and modulates the cognitive and neural processing of emotion 3 days post administration. Neuropsychopharmacology. 2008 Feb;33(3):611-8. PMID: 17473836.

" Xi Not dangerous goods.

LKT E7228 Ethacridine Lactate Monohydrate 25 g 67.9 Aromatic acridine derivative, DNA intercalator. 7-Ethoxy-3,9-acridinediamine lactate monohydrate Acrino; Rimaon; Rivano; Vucine; Acrolactine; Ethodin; Metifex 6402-23-9 ≥98% 361.39 C15H15N3O C3H6O3 H2O CCOC1=CC2=C(C3=C(C=C(C=C3)N)N=C2C=C1)N.CC(C(=O)O)O.O Ambient Ambient Partially soluble in 15 parts water. Soluble in 9 parts boiling water. "Mei Q, Li X, Liu H, et al. Effectiveness of mifepristone in combination with ethacridine lactate for second trimester pregnancy termination. Eur J Obstet Gynecol Reprod Biol. 2014 Jul;178:12-5. PMID: 24948048.

 

Oie S, Kamiya A. Microbial contamination of antiseptic-soaked cotton balls. Biol Pharm Bull. 1997 Jun;20(6):667-9. PMID: 9212987.

 

Tien KH. Intraamniotic injection of ethacridine for second-trimester induction of labor. Obstet Gynecol. 1983 Jun;61(6):733-6. PMID: 6843933.

" Xi Not dangerous goods.

LKT E7228 Ethacridine Lactate Monohydrate 50 g 122.3 Aromatic acridine derivative, DNA intercalator. 7-Ethoxy-3,9-acridinediamine lactate monohydrate Acrino; Rimaon; Rivano; Vucine; Acrolactine; Ethodin; Metifex 6402-23-9 ≥98% 361.39 C15H15N3O C3H6O3 H2O CCOC1=CC2=C(C3=C(C=C(C=C3)N)N=C2C=C1)N.CC(C(=O)O)O.O Ambient Ambient Partially soluble in 15 parts water. Soluble in 9 parts boiling water. "Mei Q, Li X, Liu H, et al. Effectiveness of mifepristone in combination with ethacridine lactate for second trimester pregnancy termination. Eur J Obstet Gynecol Reprod Biol. 2014 Jul;178:12-5. PMID: 24948048.

 

Oie S, Kamiya A. Microbial contamination of antiseptic-soaked cotton balls. Biol Pharm Bull. 1997 Jun;20(6):667-9. PMID: 9212987.

 

Tien KH. Intraamniotic injection of ethacridine for second-trimester induction of labor. Obstet Gynecol. 1983 Jun;61(6):733-6. PMID: 6843933.

" Xi Not dangerous goods.

LKT E7228 Ethacridine Lactate Monohydrate 100 g 237.8 Aromatic acridine derivative, DNA intercalator. 7-Ethoxy-3,9-acridinediamine lactate monohydrate Acrino; Rimaon; Rivano; Vucine; Acrolactine; Ethodin; Metifex 6402-23-9 ≥98% 361.39 C15H15N3O C3H6O3 H2O CCOC1=CC2=C(C3=C(C=C(C=C3)N)N=C2C=C1)N.CC(C(=O)O)O.O Ambient Ambient Partially soluble in 15 parts water. Soluble in 9 parts boiling water. "Mei Q, Li X, Liu H, et al. Effectiveness of mifepristone in combination with ethacridine lactate for second trimester pregnancy termination. Eur J Obstet Gynecol Reprod Biol. 2014 Jul;178:12-5. PMID: 24948048.

 

Oie S, Kamiya A. Microbial contamination of antiseptic-soaked cotton balls. Biol Pharm Bull. 1997 Jun;20(6):667-9. PMID: 9212987.

 

Tien KH. Intraamniotic injection of ethacridine for second-trimester induction of labor. Obstet Gynecol. 1983 Jun;61(6):733-6. PMID: 6843933.

" Xi Not dangerous goods.

LKT E7230 Ethambutol Dihydrochloride 25 g 99.8 Arabinosyl transferase inhibitor. 2,2'-(1,2-Ethanediyldiimino)bis-1-butanol (+)-2,2'-(ethylenediimino)di-1-butanol; EMB 1070-11-7 ≥98% 277.24 C10H24N2O2 CCC(CO)NCCNC(CC)CO.Cl.Cl Ambient Ambient Soluble in water. Sparingly soluble in ethanol. "Plinke C, Walter K, Aly S, et al. Mycobacterium tuberculosis embB codon 306 mutations confer moderately increased resistance to ethambutol in vitro and in vivo. Antimicrob Agents Chemother. 2011 Jun;55(6):2891-6. PMID: 21444710.

 

Kahana LM. Ethambutol in tuberculosis. Biomed Pharmacother. 1990;44(1):21-3. PMID: 1369688.

" T Not dangerous goods.

LKT E7230 Ethambutol Dihydrochloride 100 g 330.8 Arabinosyl transferase inhibitor. 2,2'-(1,2-Ethanediyldiimino)bis-1-butanol (+)-2,2'-(ethylenediimino)di-1-butanol; EMB 1070-11-7 ≥98% 277.24 C10H24N2O2 CCC(CO)NCCNC(CC)CO.Cl.Cl Ambient Ambient Soluble in water. Sparingly soluble in ethanol. "Plinke C, Walter K, Aly S, et al. Mycobacterium tuberculosis embB codon 306 mutations confer moderately increased resistance to ethambutol in vitro and in vivo. Antimicrob Agents Chemother. 2011 Jun;55(6):2891-6. PMID: 21444710.

 

Kahana LM. Ethambutol in tuberculosis. Biomed Pharmacother. 1990;44(1):21-3. PMID: 1369688.

" T Not dangerous goods.

LKT E7309 Esculetin 500 mg 50.3 Coumarin lactone found in chicory and other plant sources; β-catenin inhibitor. 6,7-Dihydroxy-2H-1-benzopyran-2-one 6,7-Dihydroxycoumarin; Cichorigenin 305-01-1 ≥98% 178.14 C9H6O4 C1=CC(=O)OC2=CC(=C(C=C21)O)O Ambient Ambient Soluble in dil alkalies, hot alcohol or glacial acetic acid. Insoluble in ether or boiling water. "Kim Y, Park Y, Namkoong S, et al. Esculetin inhibits the inflammatory response by inducing heme oxygenase-1 in cocultured macrophages and adipocytes. Food Funct. 2014 Aug 20;5(9):2371-7. PMID: 25088305.

 

Rubio V, Calviño E, García-Pérez A, et al. Human acute promyelocytic leukemia NB4 cells are sensitive to esculetin through induction of an apoptotic mechanism. Chem Biol Interact. 2014 Jul 1;220C:129-139. PMID: 24995577.

 

Medina ME, Galano A, Alvarez-Idaboy JR. Theoretical study on the peroxyl radicals scavenging activity of esculetin and its regeneration in aqueous solution. Phys Chem Chem Phys. 2014 Jan 21;16(3):1197-207. PMID: 24292723.

 

Lee SY, Lim TG, Chen H, et al. Esculetin suppresses proliferation of human colon cancer cells by directly targeting β-catenin. Cancer Prev Res (Phila). 2013 Dec;6(12):1356-64. PMID: 24104353.

 

Karmase A, Birari R, Bhutani KK. Evaluation of anti-obesity effect of Aegle marmelos leaves. Phytomedicine. 2013 Jul 15;20(10):805-12. PMID: 23632084.

 

Subramaniam SR, Ellis EM. Neuroprotective effects of umbelliferone and esculetin in a mouse model of Parkinson's disease. J Neurosci Res. 2013 Mar;91(3):453-61. PMID: 23184853.

" Xi Not dangerous goods.

LKT E7309 Esculetin 1 g 84.9 Coumarin lactone found in chicory and other plant sources; β-catenin inhibitor. 6,7-Dihydroxy-2H-1-benzopyran-2-one 6,7-Dihydroxycoumarin; Cichorigenin 305-01-1 ≥98% 178.14 C9H6O4 C1=CC(=O)OC2=CC(=C(C=C21)O)O Ambient Ambient Soluble in dil alkalies, hot alcohol or glacial acetic acid. Insoluble in ether or boiling water. "Kim Y, Park Y, Namkoong S, et al. Esculetin inhibits the inflammatory response by inducing heme oxygenase-1 in cocultured macrophages and adipocytes. Food Funct. 2014 Aug 20;5(9):2371-7. PMID: 25088305.

 

Rubio V, Calviño E, García-Pérez A, et al. Human acute promyelocytic leukemia NB4 cells are sensitive to esculetin through induction of an apoptotic mechanism. Chem Biol Interact. 2014 Jul 1;220C:129-139. PMID: 24995577.

 

Medina ME, Galano A, Alvarez-Idaboy JR. Theoretical study on the peroxyl radicals scavenging activity of esculetin and its regeneration in aqueous solution. Phys Chem Chem Phys. 2014 Jan 21;16(3):1197-207. PMID: 24292723.

 

Lee SY, Lim TG, Chen H, et al. Esculetin suppresses proliferation of human colon cancer cells by directly targeting β-catenin. Cancer Prev Res (Phila). 2013 Dec;6(12):1356-64. PMID: 24104353.

 

Karmase A, Birari R, Bhutani KK. Evaluation of anti-obesity effect of Aegle marmelos leaves. Phytomedicine. 2013 Jul 15;20(10):805-12. PMID: 23632084.

 

Subramaniam SR, Ellis EM. Neuroprotective effects of umbelliferone and esculetin in a mouse model of Parkinson's disease. J Neurosci Res. 2013 Mar;91(3):453-61. PMID: 23184853.

" Xi Not dangerous goods.

LKT E7310 Esculin 5 g 70.4 Coumarin glucoside found in Aesculus, Daphne, and Bursaria. 6-(β-D-Glucopyranosyloxy)-7-hydroxy-2H-1- benzopyran-2-one Esculin hydrate; Esculoside; Bicolorin; Enallachrome; Polychrome; Escosyl 531-75-9 ≥97% 340.28 C15H16O9 C1=CC(=O)OC2=CC(=C(C=C21)OC3C(C(C(C(O3)CO)O)O)O)O Ambient Ambient Slightly soluble in water. Soluble in methanol "Kang KS, Lee W, Jung Y, et al. Protective effect of esculin on streptozotocin-induced diabetic renal damage in mice. J Agric Food Chem. 2014 Mar 5;62(9):2069-76. PMID: 24484395.

 

Naaz F, Abdin MZ, Javed S. Protective effect of esculin against prooxidant aflatoxin B1-induced nephrotoxicity in mice. Mycotoxin Res. 2014 Feb;30(1):25-32. PMID: 24326591.

 

Raemy A, Meylan M, Casati S, et al. Phenotypic and genotypic identification of streptococci and related bacteria isolated from bovine intramammary infections. Acta Vet Scand. 2013 Jul 18;55:53. PMID: 23866930.

" None Not dangerous goods.

LKT E7310 Esculin 10 g 111.7 Coumarin glucoside found in Aesculus, Daphne, and Bursaria. 6-(β-D-Glucopyranosyloxy)-7-hydroxy-2H-1- benzopyran-2-one Esculin hydrate; Esculoside; Bicolorin; Enallachrome; Polychrome; Escosyl 531-75-9 ≥97% 340.28 C15H16O9 C1=CC(=O)OC2=CC(=C(C=C21)OC3C(C(C(C(O3)CO)O)O)O)O Ambient Ambient Slightly soluble in water. Soluble in methanol "Kang KS, Lee W, Jung Y, et al. Protective effect of esculin on streptozotocin-induced diabetic renal damage in mice. J Agric Food Chem. 2014 Mar 5;62(9):2069-76. PMID: 24484395.

 

Naaz F, Abdin MZ, Javed S. Protective effect of esculin against prooxidant aflatoxin B1-induced nephrotoxicity in mice. Mycotoxin Res. 2014 Feb;30(1):25-32. PMID: 24326591.

 

Raemy A, Meylan M, Casati S, et al. Phenotypic and genotypic identification of streptococci and related bacteria isolated from bovine intramammary infections. Acta Vet Scand. 2013 Jul 18;55:53. PMID: 23866930.

" None Not dangerous goods.

LKT E7324 Ethisterone 1 g 33.9 Synthetic steroid hormone, contraceptive; PR agonist. 17α-Hydroxypregn-4-en-20-yn-3-one Lutocyclin; Ora-Lutin; Progestoral; Trosinone 434-03-7 ≥98% 312.45 C21H28O2 CC12CCC(=O)C=C1CCC3C2CCC4(C3CCC4(C#C)O)C Ambient Ambient Slightly soluble in alcohol, acetone, ether, and chloroform. Practically insoluble in water. "Levine PM, Imberg K, Garabedian MJ, et al. Multivalent peptidomimetic conjugates: a versatile platform for modulating androgen receptor activity. J Am Chem Soc. 2012 Apr 25;134(16):6912-5. PMID: 22509763.

 

Forinash AB, Evans SL. New hormonal contraceptives: a comprehensive review of the literature. Pharmacotherapy. 2003 Dec;23(12):1573-91. PMID: 14695038.

" T Not dangerous goods.

LKT E7324 Ethisterone 5 g 67.9 Synthetic steroid hormone, contraceptive; PR agonist. 17α-Hydroxypregn-4-en-20-yn-3-one Lutocyclin; Ora-Lutin; Progestoral; Trosinone 434-03-7 ≥98% 312.45 C21H28O2 CC12CCC(=O)C=C1CCC3C2CCC4(C3CCC4(C#C)O)C Ambient Ambient Slightly soluble in alcohol, acetone, ether, and chloroform. Practically insoluble in water. "Levine PM, Imberg K, Garabedian MJ, et al. Multivalent peptidomimetic conjugates: a versatile platform for modulating androgen receptor activity. J Am Chem Soc. 2012 Apr 25;134(16):6912-5. PMID: 22509763.

 

Forinash AB, Evans SL. New hormonal contraceptives: a comprehensive review of the literature. Pharmacotherapy. 2003 Dec;23(12):1573-91. PMID: 14695038.

" T Not dangerous goods.

LKT E7324 Ethisterone 25 g 212.3 Synthetic steroid hormone, contraceptive; PR agonist. 17α-Hydroxypregn-4-en-20-yn-3-one Lutocyclin; Ora-Lutin; Progestoral; Trosinone 434-03-7 ≥98% 312.45 C21H28O2 CC12CCC(=O)C=C1CCC3C2CCC4(C3CCC4(C#C)O)C Ambient Ambient Slightly soluble in alcohol, acetone, ether, and chloroform. Practically insoluble in water. "Levine PM, Imberg K, Garabedian MJ, et al. Multivalent peptidomimetic conjugates: a versatile platform for modulating androgen receptor activity. J Am Chem Soc. 2012 Apr 25;134(16):6912-5. PMID: 22509763.

 

Forinash AB, Evans SL. New hormonal contraceptives: a comprehensive review of the literature. Pharmacotherapy. 2003 Dec;23(12):1573-91. PMID: 14695038.

" T Not dangerous goods.

LKT E7324 Ethisterone 100 g 679.5 Synthetic steroid hormone, contraceptive; PR agonist. 17α-Hydroxypregn-4-en-20-yn-3-one Lutocyclin; Ora-Lutin; Progestoral; Trosinone 434-03-7 ≥98% 312.45 C21H28O2 CC12CCC(=O)C=C1CCC3C2CCC4(C3CCC4(C#C)O)C Ambient Ambient Slightly soluble in alcohol, acetone, ether, and chloroform. Practically insoluble in water. "Levine PM, Imberg K, Garabedian MJ, et al. Multivalent peptidomimetic conjugates: a versatile platform for modulating androgen receptor activity. J Am Chem Soc. 2012 Apr 25;134(16):6912-5. PMID: 22509763.

 

Forinash AB, Evans SL. New hormonal contraceptives: a comprehensive review of the literature. Pharmacotherapy. 2003 Dec;23(12):1573-91. PMID: 14695038.

" T Not dangerous goods.

LKT E7329 Ethoxyquin 100 g 80.4 Quinoline, food preservative; HSP90 inhibitor. 6-Ethoxy-1,2-dihydro-2,2,4-trimethylquinoline EMQ; Santoflex; Santoquin 91-53-2 ≥75% 217.31 C14H19NO CCOC1=CC2=C(C=C1)NC(C=C2C)(C)C Ambient 4°C Soluble in ethanol. "Sadikot T, Swink M, Eskew JD, et al. Development of a high-throughput screening cancer cell-based luciferase refolding assay for identifying Hsp90 inhibitors. Assay Drug Dev Technol. 2013 Oct;11(8):478-88. PMID: 24127661.

 

Ørnsrud R, Arukwe A, Bohne V, et al. Investigations on the metabolism and potentially adverse effects of ethoxyquin dimer, a major metabolite of the synthetic antioxidant ethoxyquin in salmon muscle. J Food Prot. 2011 Sep;74(9):1574-80. PMID: 21902931.

 

Kumar S, Engman L, Valgimigli L, et al. Antioxidant profile of ethoxyquin and some of its S, Se, and Te analogues. J Org Chem. 2007 Aug 3;72(16):6046-55. PMID: 17602530.

" Xn Not dangerous goods.

LKT E7329 Ethoxyquin 250 g 174.7 Quinoline, food preservative; HSP90 inhibitor. 6-Ethoxy-1,2-dihydro-2,2,4-trimethylquinoline EMQ; Santoflex; Santoquin 91-53-2 ≥75% 217.31 C14H19NO CCOC1=CC2=C(C=C1)NC(C=C2C)(C)C Ambient 4°C Soluble in ethanol. "Sadikot T, Swink M, Eskew JD, et al. Development of a high-throughput screening cancer cell-based luciferase refolding assay for identifying Hsp90 inhibitors. Assay Drug Dev Technol. 2013 Oct;11(8):478-88. PMID: 24127661.

 

Ørnsrud R, Arukwe A, Bohne V, et al. Investigations on the metabolism and potentially adverse effects of ethoxyquin dimer, a major metabolite of the synthetic antioxidant ethoxyquin in salmon muscle. J Food Prot. 2011 Sep;74(9):1574-80. PMID: 21902931.

 

Kumar S, Engman L, Valgimigli L, et al. Antioxidant profile of ethoxyquin and some of its S, Se, and Te analogues. J Org Chem. 2007 Aug 3;72(16):6046-55. PMID: 17602530.

" Xn Not dangerous goods.

LKT E7329 Ethoxyquin 1 kg 567.6 Quinoline, food preservative; HSP90 inhibitor. 6-Ethoxy-1,2-dihydro-2,2,4-trimethylquinoline EMQ; Santoflex; Santoquin 91-53-2 ≥75% 217.31 C14H19NO CCOC1=CC2=C(C=C1)NC(C=C2C)(C)C Ambient 4°C Soluble in ethanol. "Sadikot T, Swink M, Eskew JD, et al. Development of a high-throughput screening cancer cell-based luciferase refolding assay for identifying Hsp90 inhibitors. Assay Drug Dev Technol. 2013 Oct;11(8):478-88. PMID: 24127661.

 

Ørnsrud R, Arukwe A, Bohne V, et al. Investigations on the metabolism and potentially adverse effects of ethoxyquin dimer, a major metabolite of the synthetic antioxidant ethoxyquin in salmon muscle. J Food Prot. 2011 Sep;74(9):1574-80. PMID: 21902931.

 

Kumar S, Engman L, Valgimigli L, et al. Antioxidant profile of ethoxyquin and some of its S, Se, and Te analogues. J Org Chem. 2007 Aug 3;72(16):6046-55. PMID: 17602530.

" Xn Not dangerous goods.

LKT E7357 Esomeprazole Potassium 25 mg 111 (S) isomer of omeprazole; H+/K+ ATPase and MAO-A/B inhibitor. 6-methoxy-2-[(4-methoxy-3,5-dimethylpyridin-2-yl)methylsulfinyl]-1H-benzimidazole Omeprazole potassium 161796-84-5 ≥98% 383.51 C17H18N3O3S K<sub> CC1=CN=C(C(=C1OC)C)CS(=O)C2=NC3=C([N-]2)C=CC(=C3)OC.[K+] Ambient Ambient "Sugano K, Choi MG, Lin JT, et al. Multinational, double-blind, randomised, placebo-controlled, prospective study of esomeprazole in the prevention of recurrent peptic ulcer in low-dose acetylsalicylic acid users: the LAVENDER study. Gut. 2013 Dec 10. [Epub ahead of print]. PMID: 24326741.

 

Costa-Rodrigues J, Reis S, Teixeira S, et al. Dose-dependent inhibitory effects of proton pump inhibitors on human osteoclastic and osteoblastic cell activity. FEBS J. 2013 Oct;280(20):5052-64. PMID: 23937530.

 

Petzer A, Pienaar A, Petzer JP. The inhibition of monoamine oxidase by esomeprazole. Drug Res (Stuttg). 2013 Sep;63(9):462-7. PMID: 23677700.

 

Marino ML, Fais S, Djavaheri-Mergny M, et al. Proton pump inhibition induces autophagy as a survival mechanism following oxidative stress in human melanoma cells. Cell Death Dis. 2010 Oct 21;1:e87. PMID: 21368860.

 

Saccar CL. The pharmacology of esomeprazole and its role in gastric acid related diseases. Expert Opin Drug Metab Toxicol. 2009 Sep;5(9):1113-24. PMID: 19606942.

" Not dangerous goods.

LKT E7357 Esomeprazole Potassium 100 mg 312.3 (S) isomer of omeprazole; H+/K+ ATPase and MAO-A/B inhibitor. 6-methoxy-2-[(4-methoxy-3,5-dimethylpyridin-2-yl)methylsulfinyl]-1H-benzimidazole Omeprazole potassium 161796-84-5 ≥98% 383.51 C17H18N3O3S K<sub> CC1=CN=C(C(=C1OC)C)CS(=O)C2=NC3=C([N-]2)C=CC(=C3)OC.[K+] Ambient Ambient "Sugano K, Choi MG, Lin JT, et al. Multinational, double-blind, randomised, placebo-controlled, prospective study of esomeprazole in the prevention of recurrent peptic ulcer in low-dose acetylsalicylic acid users: the LAVENDER study. Gut. 2013 Dec 10. [Epub ahead of print]. PMID: 24326741.

 

Costa-Rodrigues J, Reis S, Teixeira S, et al. Dose-dependent inhibitory effects of proton pump inhibitors on human osteoclastic and osteoblastic cell activity. FEBS J. 2013 Oct;280(20):5052-64. PMID: 23937530.

 

Petzer A, Pienaar A, Petzer JP. The inhibition of monoamine oxidase by esomeprazole. Drug Res (Stuttg). 2013 Sep;63(9):462-7. PMID: 23677700.

 

Marino ML, Fais S, Djavaheri-Mergny M, et al. Proton pump inhibition induces autophagy as a survival mechanism following oxidative stress in human melanoma cells. Cell Death Dis. 2010 Oct 21;1:e87. PMID: 21368860.

 

Saccar CL. The pharmacology of esomeprazole and its role in gastric acid related diseases. Expert Opin Drug Metab Toxicol. 2009 Sep;5(9):1113-24. PMID: 19606942.

" Not dangerous goods.

LKT E7357 Esomeprazole Potassium 500 mg 1270.7 (S) isomer of omeprazole; H+/K+ ATPase and MAO-A/B inhibitor. 6-methoxy-2-[(4-methoxy-3,5-dimethylpyridin-2-yl)methylsulfinyl]-1H-benzimidazole Omeprazole potassium 161796-84-5 ≥98% 383.51 C17H18N3O3S K<sub> CC1=CN=C(C(=C1OC)C)CS(=O)C2=NC3=C([N-]2)C=CC(=C3)OC.[K+] Ambient Ambient "Sugano K, Choi MG, Lin JT, et al. Multinational, double-blind, randomised, placebo-controlled, prospective study of esomeprazole in the prevention of recurrent peptic ulcer in low-dose acetylsalicylic acid users: the LAVENDER study. Gut. 2013 Dec 10. [Epub ahead of print]. PMID: 24326741.

 

Costa-Rodrigues J, Reis S, Teixeira S, et al. Dose-dependent inhibitory effects of proton pump inhibitors on human osteoclastic and osteoblastic cell activity. FEBS J. 2013 Oct;280(20):5052-64. PMID: 23937530.

 

Petzer A, Pienaar A, Petzer JP. The inhibition of monoamine oxidase by esomeprazole. Drug Res (Stuttg). 2013 Sep;63(9):462-7. PMID: 23677700.

 

Marino ML, Fais S, Djavaheri-Mergny M, et al. Proton pump inhibition induces autophagy as a survival mechanism following oxidative stress in human melanoma cells. Cell Death Dis. 2010 Oct 21;1:e87. PMID: 21368860.

 

Saccar CL. The pharmacology of esomeprazole and its role in gastric acid related diseases. Expert Opin Drug Metab Toxicol. 2009 Sep;5(9):1113-24. PMID: 19606942.

" Not dangerous goods.

LKT E7376 Estradiol 1 g 51.1 Endogenous steroid hormone, involved in regulation of menstrual cycle and growth of reproductive organs, used in HRT; ER agonist. (17β)-Estra-1,3,5(10)-triene-3,17-diol Dimenformon; Estrace; Estraderm; Evorel; Macrodiol; Menorest; Profoliol B; Systen; Vagifem; Zumenon 50-28-2 ≥97% 272.38 C18H24O2 CC12CCC3C(C1CCC2O)CCC4=C3C=CC(=C4)O Ambient Ambient Soluble in alcohol (35 mg/mL), acetone, dioxane, and other organic solvent. Insoluble in water. "Pentikäinen V, Erkkilä K, Suomalainen L, et al. Estradiol acts as a germ cell survival factor in the human testis in vitro. J Clin Endocrinol Metab. 2000 May;85(5):2057-67. PMID: 10843196.

 

Behl C, Widmann M, Trapp T, et al. 17-beta estradiol protects neurons from oxidative stress-induced cell death in vitro. Biochem Biophys Res Commun. 1995 Nov 13;216(2):473-82. PMID: 7488136.

 

Collins P, Rosano GM, Sarrel PM, et al. 17 beta-Estradiol attenuates acetylcholine-induced coronary arterial constriction in women but not men with coronary heart disease. Circulation. 1995 Jul 1;92(1):24-30. PMID: 7788912.

 

Carruba G, Pfeffer U, Fecarotta E, et al. Estradiol inhibits growth of hormone-nonresponsive PC3 human prostate cancer cells. Cancer Res. 1994 Mar 1;54(5):1190-3. PMID: 8118804.

" Repr., Carc Not dangerous goods.

LKT E7376 Estradiol 5 g 208 Endogenous steroid hormone, involved in regulation of menstrual cycle and growth of reproductive organs, used in HRT; ER agonist. (17β)-Estra-1,3,5(10)-triene-3,17-diol Dimenformon; Estrace; Estraderm; Evorel; Macrodiol; Menorest; Profoliol B; Systen; Vagifem; Zumenon 50-28-2 ≥97% 272.38 C18H24O2 CC12CCC3C(C1CCC2O)CCC4=C3C=CC(=C4)O Ambient Ambient Soluble in alcohol (35 mg/mL), acetone, dioxane, and other organic solvent. Insoluble in water. "Pentikäinen V, Erkkilä K, Suomalainen L, et al. Estradiol acts as a germ cell survival factor in the human testis in vitro. J Clin Endocrinol Metab. 2000 May;85(5):2057-67. PMID: 10843196.

 

Behl C, Widmann M, Trapp T, et al. 17-beta estradiol protects neurons from oxidative stress-induced cell death in vitro. Biochem Biophys Res Commun. 1995 Nov 13;216(2):473-82. PMID: 7488136.

 

Collins P, Rosano GM, Sarrel PM, et al. 17 beta-Estradiol attenuates acetylcholine-induced coronary arterial constriction in women but not men with coronary heart disease. Circulation. 1995 Jul 1;92(1):24-30. PMID: 7788912.

 

Carruba G, Pfeffer U, Fecarotta E, et al. Estradiol inhibits growth of hormone-nonresponsive PC3 human prostate cancer cells. Cancer Res. 1994 Mar 1;54(5):1190-3. PMID: 8118804.

" Repr., Carc Not dangerous goods.

LKT E7376 Estradiol 25 g 681.7 Endogenous steroid hormone, involved in regulation of menstrual cycle and growth of reproductive organs, used in HRT; ER agonist. (17β)-Estra-1,3,5(10)-triene-3,17-diol Dimenformon; Estrace; Estraderm; Evorel; Macrodiol; Menorest; Profoliol B; Systen; Vagifem; Zumenon 50-28-2 ≥97% 272.38 C18H24O2 CC12CCC3C(C1CCC2O)CCC4=C3C=CC(=C4)O Ambient Ambient Soluble in alcohol (35 mg/mL), acetone, dioxane, and other organic solvent. Insoluble in water. "Pentikäinen V, Erkkilä K, Suomalainen L, et al. Estradiol acts as a germ cell survival factor in the human testis in vitro. J Clin Endocrinol Metab. 2000 May;85(5):2057-67. PMID: 10843196.

 

Behl C, Widmann M, Trapp T, et al. 17-beta estradiol protects neurons from oxidative stress-induced cell death in vitro. Biochem Biophys Res Commun. 1995 Nov 13;216(2):473-82. PMID: 7488136.

 

Collins P, Rosano GM, Sarrel PM, et al. 17 beta-Estradiol attenuates acetylcholine-induced coronary arterial constriction in women but not men with coronary heart disease. Circulation. 1995 Jul 1;92(1):24-30. PMID: 7788912.

 

Carruba G, Pfeffer U, Fecarotta E, et al. Estradiol inhibits growth of hormone-nonresponsive PC3 human prostate cancer cells. Cancer Res. 1994 Mar 1;54(5):1190-3. PMID: 8118804.

" Repr., Carc Not dangerous goods.

LKT E7377 Estriol 100 mg 27.3 Endogenous steroid hormone, estradiol metabolite, used in HRT; ER agonist. (16α,17β)-Estra-1,3,5(10)-triene-3,16,17-triol Aacifemine; Colpogyn; Destriol; Oekolp; Ovesterin; Theelol; Tridestrin 50-27-1 ≥97% 288.38 C18H24O3 CC12CCC3C(C1CC(C2O)O)CCC4=C3C=CC(=C4)O Ambient Ambient Soluble in alcohol, dioxane, chloroform, ether, vegetable oils, pyridine or fixed alkali hydroxide solutions. "Jana P, Maiti S, Kahn NN, et al. Estriol-induced fibrinolysis due to the activation of plasminogen to plasmin by nitric oxide synthesis in platelets. Blood Coagul Fibrinolysis. 2014 Apr 2. [Epub ahead of print]. PMID: 24695088.

 

Tiwari-Woodruff S, Voskuhl RR. Neuroprotective and anti-inflammatory effects of estrogen receptor ligand treatment in mice. J Neurol Sci. 2009 Nov 15;286(1-2):81-5. PMID: 19442988.

 

Huang R, Kaji Y, Fukuda S, et al. Experimental use of estriol for visualizing the vitreous body in the anterior chamber after posterior capsule rupture in animal models. J Cataract Refract Surg. 2009 Jul;35(7):1260-5. PMID: 19545818.

 

Melamed M, Castaño E, Notides AC, et al. Molecular and kinetic basis for the mixed agonist/antagonist activity of estriol. Mol Endocrinol. 1997 Nov;11(12):1868-78. PMID: 9369454.

" Carc., Repr. Not dangerous goods.

LKT E7377 Estriol 500 mg 63.1 Endogenous steroid hormone, estradiol metabolite, used in HRT; ER agonist. (16α,17β)-Estra-1,3,5(10)-triene-3,16,17-triol Aacifemine; Colpogyn; Destriol; Oekolp; Ovesterin; Theelol; Tridestrin 50-27-1 ≥97% 288.38 C18H24O3 CC12CCC3C(C1CC(C2O)O)CCC4=C3C=CC(=C4)O Ambient Ambient Soluble in alcohol, dioxane, chloroform, ether, vegetable oils, pyridine or fixed alkali hydroxide solutions. "Jana P, Maiti S, Kahn NN, et al. Estriol-induced fibrinolysis due to the activation of plasminogen to plasmin by nitric oxide synthesis in platelets. Blood Coagul Fibrinolysis. 2014 Apr 2. [Epub ahead of print]. PMID: 24695088.

 

Tiwari-Woodruff S, Voskuhl RR. Neuroprotective and anti-inflammatory effects of estrogen receptor ligand treatment in mice. J Neurol Sci. 2009 Nov 15;286(1-2):81-5. PMID: 19442988.

 

Huang R, Kaji Y, Fukuda S, et al. Experimental use of estriol for visualizing the vitreous body in the anterior chamber after posterior capsule rupture in animal models. J Cataract Refract Surg. 2009 Jul;35(7):1260-5. PMID: 19545818.

 

Melamed M, Castaño E, Notides AC, et al. Molecular and kinetic basis for the mixed agonist/antagonist activity of estriol. Mol Endocrinol. 1997 Nov;11(12):1868-78. PMID: 9369454.

" Carc., Repr. Not dangerous goods.

LKT E7377 Estriol 1 g 109.2 Endogenous steroid hormone, estradiol metabolite, used in HRT; ER agonist. (16α,17β)-Estra-1,3,5(10)-triene-3,16,17-triol Aacifemine; Colpogyn; Destriol; Oekolp; Ovesterin; Theelol; Tridestrin 50-27-1 ≥97% 288.38 C18H24O3 CC12CCC3C(C1CC(C2O)O)CCC4=C3C=CC(=C4)O Ambient Ambient Soluble in alcohol, dioxane, chloroform, ether, vegetable oils, pyridine or fixed alkali hydroxide solutions. "Jana P, Maiti S, Kahn NN, et al. Estriol-induced fibrinolysis due to the activation of plasminogen to plasmin by nitric oxide synthesis in platelets. Blood Coagul Fibrinolysis. 2014 Apr 2. [Epub ahead of print]. PMID: 24695088.

 

Tiwari-Woodruff S, Voskuhl RR. Neuroprotective and anti-inflammatory effects of estrogen receptor ligand treatment in mice. J Neurol Sci. 2009 Nov 15;286(1-2):81-5. PMID: 19442988.

 

Huang R, Kaji Y, Fukuda S, et al. Experimental use of estriol for visualizing the vitreous body in the anterior chamber after posterior capsule rupture in animal models. J Cataract Refract Surg. 2009 Jul;35(7):1260-5. PMID: 19545818.

 

Melamed M, Castaño E, Notides AC, et al. Molecular and kinetic basis for the mixed agonist/antagonist activity of estriol. Mol Endocrinol. 1997 Nov;11(12):1868-78. PMID: 9369454.

" Carc., Repr. Not dangerous goods.

LKT E7378 Estrone 1 g 27.2 Endogenous steroid hormone, estriol precursor; ER agonist. 3-Hydroxyestra-1,3,5(10)-tri-en-17-onne Oestrone; Flliculinn; Tokokin; Hiestrone; Glandubolin; Kolponn; Homrovarine; Wynestron; Kestron; Follestrine 53-16-7 ≥97% 270.37 C18H22O2 CC12CCC3C(C1CCC2=O)CCC4=C3C=CC(=C4)O Ambient Ambient Insoluble in water, Sparingly soluble in ethanol (4 mg/mL). Soluble in acetone (20 mg/mL at 50 oC), chloroform, benzene, dioxane, pyridine or fixed alkali hydroxide solutions. "Rizzati V, Rathahao E, Gamet-Payrastre L, et al. In vitro aromatic bioactivation of the weak estrogen E(2)alpha and genesis of DNA adducts. Steroids. 2005 Mar;70(3):161-72. PMID: 15763594.

 

Borges C, Lemière F, Embrechts J, et al. Characterisation of estrone-nucleic acid adducts formed by reaction of 3,4-estrone-o-quinone with 2'-deoxynucleosides/deoxynucleotides using capillary liquid chromatography/electrospray ionization mass spectrometry. Rapid Commun Mass Spectrom. 2004;18(19):2191-200. PMID: 15384136.

" Carc., Repr. Not dangerous goods.

LKT E7378 Estrone 5 g 92.5 Endogenous steroid hormone, estriol precursor; ER agonist. 3-Hydroxyestra-1,3,5(10)-tri-en-17-onne Oestrone; Flliculinn; Tokokin; Hiestrone; Glandubolin; Kolponn; Homrovarine; Wynestron; Kestron; Follestrine 53-16-7 ≥97% 270.37 C18H22O2 CC12CCC3C(C1CCC2=O)CCC4=C3C=CC(=C4)O Ambient Ambient Insoluble in water, Sparingly soluble in ethanol (4 mg/mL). Soluble in acetone (20 mg/mL at 50 oC), chloroform, benzene, dioxane, pyridine or fixed alkali hydroxide solutions. "Rizzati V, Rathahao E, Gamet-Payrastre L, et al. In vitro aromatic bioactivation of the weak estrogen E(2)alpha and genesis of DNA adducts. Steroids. 2005 Mar;70(3):161-72. PMID: 15763594.

 

Borges C, Lemière F, Embrechts J, et al. Characterisation of estrone-nucleic acid adducts formed by reaction of 3,4-estrone-o-quinone with 2'-deoxynucleosides/deoxynucleotides using capillary liquid chromatography/electrospray ionization mass spectrometry. Rapid Commun Mass Spectrom. 2004;18(19):2191-200. PMID: 15384136.

" Carc., Repr. Not dangerous goods.

LKT E7378 Estrone 25 g 305.9 Endogenous steroid hormone, estriol precursor; ER agonist. 3-Hydroxyestra-1,3,5(10)-tri-en-17-onne Oestrone; Flliculinn; Tokokin; Hiestrone; Glandubolin; Kolponn; Homrovarine; Wynestron; Kestron; Follestrine 53-16-7 ≥97% 270.37 C18H22O2 CC12CCC3C(C1CCC2=O)CCC4=C3C=CC(=C4)O Ambient Ambient Insoluble in water, Sparingly soluble in ethanol (4 mg/mL). Soluble in acetone (20 mg/mL at 50 oC), chloroform, benzene, dioxane, pyridine or fixed alkali hydroxide solutions. "Rizzati V, Rathahao E, Gamet-Payrastre L, et al. In vitro aromatic bioactivation of the weak estrogen E(2)alpha and genesis of DNA adducts. Steroids. 2005 Mar;70(3):161-72. PMID: 15763594.

 

Borges C, Lemière F, Embrechts J, et al. Characterisation of estrone-nucleic acid adducts formed by reaction of 3,4-estrone-o-quinone with 2'-deoxynucleosides/deoxynucleotides using capillary liquid chromatography/electrospray ionization mass spectrometry. Rapid Commun Mass Spectrom. 2004;18(19):2191-200. PMID: 15384136.

" Carc., Repr. Not dangerous goods.

LKT E7433 Etidronate Disodium 1 g 96.2 Bisphosphonate, chelating agent. (1-Hydroxyethylidene)bisphosphonic acid disodium salt Disodium dihydrogen (1-hydroxyethylidene)bis- [phosphate]; Didronel; Diphos; Etidron 7414-83-7 ≥98% 249.99 C2H6Na2O7P2 CC(O)(P(=O)(O)[O-])P(=O)(O)[O-].[Na+].[Na+] Ambient Ambient Soluble in water (26mg/mL). "Asano S, Suzuki A, Itoh M. Etidronate for treatment of osteoporosis. Nihon Rinsho. 2009 May;67(5):938-42. PMID: 19432113.

 

Lomashvili KA, Monier-Faugere MC, Wang X, et al. Effect of bisphosphonates on vascular calcification and bone metabolism in experimental renal failure. Kidney Int. 2009 Mar;75(6):617-25. PMID: 19129793.

 

Suzuki Y, Nishiyama T, Hasuda K, et al. Effect of etidronate on COX-2 expression and PGE(2) production in macrophage-like RAW 264.7 cells stimulated by titanium particles. J Orthop Sci. 2007 Nov;12(6):568-77. PMID: 18040640.

" Not dangerous goods.

LKT E7433 Etidronate Disodium 5 g 384.1 Bisphosphonate, chelating agent. (1-Hydroxyethylidene)bisphosphonic acid disodium salt Disodium dihydrogen (1-hydroxyethylidene)bis- [phosphate]; Didronel; Diphos; Etidron 7414-83-7 ≥98% 249.99 C2H6Na2O7P2 CC(O)(P(=O)(O)[O-])P(=O)(O)[O-].[Na+].[Na+] Ambient Ambient Soluble in water (26mg/mL). "Asano S, Suzuki A, Itoh M. Etidronate for treatment of osteoporosis. Nihon Rinsho. 2009 May;67(5):938-42. PMID: 19432113.

 

Lomashvili KA, Monier-Faugere MC, Wang X, et al. Effect of bisphosphonates on vascular calcification and bone metabolism in experimental renal failure. Kidney Int. 2009 Mar;75(6):617-25. PMID: 19129793.

 

Suzuki Y, Nishiyama T, Hasuda K, et al. Effect of etidronate on COX-2 expression and PGE(2) production in macrophage-like RAW 264.7 cells stimulated by titanium particles. J Orthop Sci. 2007 Nov;12(6):568-77. PMID: 18040640.

" Not dangerous goods.

LKT E7556 Etodolac 100 mg 67.9 NSAID; TRPA1 agonist, COX-2 inhibitor. "Pyrano(3,4-b)indole-1-acetic acid, 1,8-diethyl-1,3,4,9-

tetrahydro-" Etodolic acid; Etogesic; Lodine; Tedolan; Ultradol. 41340-25-4 ≥98% 287.35 C17H21NO3 CCC1=CC=CC2=C1NC3=C2CCOC3(CC)CC(=O)O Ambient 4°C Soluble in alcohols, chloroform, DMSO or aqueous polyethylene glycol. "Wang S, Dai Y, Kogure Y, et al. Etodolac activates and desensitizes transient receptor potential ankyrin 1. J Neurosci Res. 2013 Dec;91(12):1591-8. PMID: 24027177.

 

Adachi T, Tajima Y, Kuroki T, et al. Chemopreventive effects of a selective cyclooxygenase-2 inhibitor (etodolac) on chemically induced intraductal papillary carcinoma of the pancreas in hamsters. Carcinogenesis. 2008 Apr;29(4):830-3. PMID: 18296437.

 

Fernandes E, Costa D, Toste SA, et al. In vitro scavenging activity for reactive oxygen and nitrogen species by nonsteroidal anti-inflammatory indole, pyrrole, and oxazole derivative drugs. Free Radic Biol Med. 2004 Dec 1;37(11):1895-905. PMID: 15528048.

 

Cheng J, Imanishi H, Liu W, et al. Involvement of cell cycle regulatory proteins and MAP kinase signaling pathway in growth inhibition and cell cycle arrest by a selective cyclooxygenase 2 inhibitor, etodolac, in human hepatocellular carcinoma cell lines. Cancer Sci. 2004 Aug;95(8):666-73. PMID: 15298730.

" T, "UN number: 2811     Class: 6.1     Packing Group: III

Proper shipping name: Toxic solid, organic, n.o.s. (Etodolac)"

LKT E7556 Etodolac 250 mg 149.5 NSAID; TRPA1 agonist, COX-2 inhibitor. "Pyrano(3,4-b)indole-1-acetic acid, 1,8-diethyl-1,3,4,9-

tetrahydro-" Etodolic acid; Etogesic; Lodine; Tedolan; Ultradol. 41340-25-4 ≥98% 287.35 C17H21NO3 CCC1=CC=CC2=C1NC3=C2CCOC3(CC)CC(=O)O Ambient 4°C Soluble in alcohols, chloroform, DMSO or aqueous polyethylene glycol. "Wang S, Dai Y, Kogure Y, et al. Etodolac activates and desensitizes transient receptor potential ankyrin 1. J Neurosci Res. 2013 Dec;91(12):1591-8. PMID: 24027177.

 

Adachi T, Tajima Y, Kuroki T, et al. Chemopreventive effects of a selective cyclooxygenase-2 inhibitor (etodolac) on chemically induced intraductal papillary carcinoma of the pancreas in hamsters. Carcinogenesis. 2008 Apr;29(4):830-3. PMID: 18296437.

 

Fernandes E, Costa D, Toste SA, et al. In vitro scavenging activity for reactive oxygen and nitrogen species by nonsteroidal anti-inflammatory indole, pyrrole, and oxazole derivative drugs. Free Radic Biol Med. 2004 Dec 1;37(11):1895-905. PMID: 15528048.

 

Cheng J, Imanishi H, Liu W, et al. Involvement of cell cycle regulatory proteins and MAP kinase signaling pathway in growth inhibition and cell cycle arrest by a selective cyclooxygenase 2 inhibitor, etodolac, in human hepatocellular carcinoma cell lines. Cancer Sci. 2004 Aug;95(8):666-73. PMID: 15298730.

" T, "UN number: 2811     Class: 6.1     Packing Group: III

Proper shipping name: Toxic solid, organic, n.o.s. (Etodolac)"

LKT E7556 Etodolac 1 g 407.7 NSAID; TRPA1 agonist, COX-2 inhibitor. "Pyrano(3,4-b)indole-1-acetic acid, 1,8-diethyl-1,3,4,9-

tetrahydro-" Etodolic acid; Etogesic; Lodine; Tedolan; Ultradol. 41340-25-4 ≥98% 287.35 C17H21NO3 CCC1=CC=CC2=C1NC3=C2CCOC3(CC)CC(=O)O Ambient 4°C Soluble in alcohols, chloroform, DMSO or aqueous polyethylene glycol. "Wang S, Dai Y, Kogure Y, et al. Etodolac activates and desensitizes transient receptor potential ankyrin 1. J Neurosci Res. 2013 Dec;91(12):1591-8. PMID: 24027177.

 

Adachi T, Tajima Y, Kuroki T, et al. Chemopreventive effects of a selective cyclooxygenase-2 inhibitor (etodolac) on chemically induced intraductal papillary carcinoma of the pancreas in hamsters. Carcinogenesis. 2008 Apr;29(4):830-3. PMID: 18296437.

 

Fernandes E, Costa D, Toste SA, et al. In vitro scavenging activity for reactive oxygen and nitrogen species by nonsteroidal anti-inflammatory indole, pyrrole, and oxazole derivative drugs. Free Radic Biol Med. 2004 Dec 1;37(11):1895-905. PMID: 15528048.

 

Cheng J, Imanishi H, Liu W, et al. Involvement of cell cycle regulatory proteins and MAP kinase signaling pathway in growth inhibition and cell cycle arrest by a selective cyclooxygenase 2 inhibitor, etodolac, in human hepatocellular carcinoma cell lines. Cancer Sci. 2004 Aug;95(8):666-73. PMID: 15298730.

" T, "UN number: 2811     Class: 6.1     Packing Group: III

Proper shipping name: Toxic solid, organic, n.o.s. (Etodolac)"

LKT E7578 Estramustine 100 mg 149.9 Nitrogen mustard and estradiol derivative; microtubule depolymerization inducer. 2998-57-4  ≥97% 440.4 C23H31Cl2NO3 CC12CCC3C(C1CCC2O)CCC4=C3C=CC(=C4)OC(=O)N(CCCl)CCCl Ambient 4°C "Matsumoto K, Tanaka N, Hayakawa N, et al. Efficacy of estramustine phosphate sodium hydrate (EMP) monotherapy in castration-resistant prostate cancer patients: report of 102 cases and review of literature. Med Oncol. 2013 Dec;30(4):717. PMID: 24005812.

 

Mohan R, Panda D. Kinetic stabilization of microtubule dynamics by estramustine is associated with tubulin acetylation, spindle abnormalities, and mitotic arrest. Cancer Res. 2008 Aug 1;68(15):6181-9. PMID: 18676841.

 

Yoshida D, Hoshino S, Shimura T, et al. Drug-induced apoptosis by anti-microtubule agent, estramustine phosphate on human malignant glioma cell line, U87MG; in vitro study. J Neurooncol. 2000 Apr;47(2):133-40. PMID: 10982154.

 

Panda D, Miller HP, Islam K, et al. Stabilization of microtubule dynamics by estramustine by binding to a novel site in tubulin: a possible mechanistic basis for its antitumor action. Proc Natl Acad Sci U S A. 1997 Sep 30;94(20):10560-4. PMID: 9380674.

 

Punzi JS, Duax WL, Strong P, et al. Molecular conformation of estramustine and two analogues. Mol Pharmacol. 1992 Mar;41(3):569-76. PMID: 1545778.

" Not dangerous goods.

LKT E7578 Estramustine 250 mg 298.9 Nitrogen mustard and estradiol derivative; microtubule depolymerization inducer. 2998-57-4  ≥97% 440.4 C23H31Cl2NO3 CC12CCC3C(C1CCC2O)CCC4=C3C=CC(=C4)OC(=O)N(CCCl)CCCl Ambient 4°C "Matsumoto K, Tanaka N, Hayakawa N, et al. Efficacy of estramustine phosphate sodium hydrate (EMP) monotherapy in castration-resistant prostate cancer patients: report of 102 cases and review of literature. Med Oncol. 2013 Dec;30(4):717. PMID: 24005812.

 

Mohan R, Panda D. Kinetic stabilization of microtubule dynamics by estramustine is associated with tubulin acetylation, spindle abnormalities, and mitotic arrest. Cancer Res. 2008 Aug 1;68(15):6181-9. PMID: 18676841.

 

Yoshida D, Hoshino S, Shimura T, et al. Drug-induced apoptosis by anti-microtubule agent, estramustine phosphate on human malignant glioma cell line, U87MG; in vitro study. J Neurooncol. 2000 Apr;47(2):133-40. PMID: 10982154.

 

Panda D, Miller HP, Islam K, et al. Stabilization of microtubule dynamics by estramustine by binding to a novel site in tubulin: a possible mechanistic basis for its antitumor action. Proc Natl Acad Sci U S A. 1997 Sep 30;94(20):10560-4. PMID: 9380674.

 

Punzi JS, Duax WL, Strong P, et al. Molecular conformation of estramustine and two analogues. Mol Pharmacol. 1992 Mar;41(3):569-76. PMID: 1545778.

" Not dangerous goods.

LKT E7578 Estramustine 1 g 924.1 Nitrogen mustard and estradiol derivative; microtubule depolymerization inducer. 2998-57-4  ≥97% 440.4 C23H31Cl2NO3 CC12CCC3C(C1CCC2O)CCC4=C3C=CC(=C4)OC(=O)N(CCCl)CCCl Ambient 4°C "Matsumoto K, Tanaka N, Hayakawa N, et al. Efficacy of estramustine phosphate sodium hydrate (EMP) monotherapy in castration-resistant prostate cancer patients: report of 102 cases and review of literature. Med Oncol. 2013 Dec;30(4):717. PMID: 24005812.

 

Mohan R, Panda D. Kinetic stabilization of microtubule dynamics by estramustine is associated with tubulin acetylation, spindle abnormalities, and mitotic arrest. Cancer Res. 2008 Aug 1;68(15):6181-9. PMID: 18676841.

 

Yoshida D, Hoshino S, Shimura T, et al. Drug-induced apoptosis by anti-microtubule agent, estramustine phosphate on human malignant glioma cell line, U87MG; in vitro study. J Neurooncol. 2000 Apr;47(2):133-40. PMID: 10982154.

 

Panda D, Miller HP, Islam K, et al. Stabilization of microtubule dynamics by estramustine by binding to a novel site in tubulin: a possible mechanistic basis for its antitumor action. Proc Natl Acad Sci U S A. 1997 Sep 30;94(20):10560-4. PMID: 9380674.

 

Punzi JS, Duax WL, Strong P, et al. Molecular conformation of estramustine and two analogues. Mol Pharmacol. 1992 Mar;41(3):569-76. PMID: 1545778.

" Not dangerous goods.

LKT E7579 Estramustine Phosphate Disodium 100 mg 149.9 Nitrogen mustard and estradiol derivative; microtubule depolymerization inducer. 52205-73-9  ≥95% 564.35 C23H32Cl2NO6PNa2 CC12CCC3C(C1CCC2OP(=O)([O-])[O-])CCC4=C3C=CC(=C4)OC(=O)N(CCCl)CCCl.[Na+].[Na+] Ambient 4°C "Matsumoto K, Tanaka N, Hayakawa N, et al. Efficacy of estramustine phosphate sodium hydrate (EMP) monotherapy in castration-resistant prostate cancer patients: report of 102 cases and review of literature. Med Oncol. 2013 Dec;30(4):717. PMID: 24005812.

 

Mohan R, Panda D. Kinetic stabilization of microtubule dynamics by estramustine is associated with tubulin acetylation, spindle abnormalities, and mitotic arrest. Cancer Res. 2008 Aug 1;68(15):6181-9. PMID: 18676841.

 

Yoshida D, Hoshino S, Shimura T, et al. Drug-induced apoptosis by anti-microtubule agent, estramustine phosphate on human malignant glioma cell line, U87MG; in vitro study. J Neurooncol. 2000 Apr;47(2):133-40. PMID: 10982154.

 

Panda D, Miller HP, Islam K, et al. Stabilization of microtubule dynamics by estramustine by binding to a novel site in tubulin: a possible mechanistic basis for its antitumor action. Proc Natl Acad Sci U S A. 1997 Sep 30;94(20):10560-4. PMID: 9380674.

 

Punzi JS, Duax WL, Strong P, et al. Molecular conformation of estramustine and two analogues. Mol Pharmacol. 1992 Mar;41(3):569-76. PMID: 1545778.

" Not dangerous goods.

LKT E7579 Estramustine Phosphate Disodium 250 mg 298.9 Nitrogen mustard and estradiol derivative; microtubule depolymerization inducer. 52205-73-9  ≥95% 564.35 C23H32Cl2NO6PNa2 CC12CCC3C(C1CCC2OP(=O)([O-])[O-])CCC4=C3C=CC(=C4)OC(=O)N(CCCl)CCCl.[Na+].[Na+] Ambient 4°C "Matsumoto K, Tanaka N, Hayakawa N, et al. Efficacy of estramustine phosphate sodium hydrate (EMP) monotherapy in castration-resistant prostate cancer patients: report of 102 cases and review of literature. Med Oncol. 2013 Dec;30(4):717. PMID: 24005812.

 

Mohan R, Panda D. Kinetic stabilization of microtubule dynamics by estramustine is associated with tubulin acetylation, spindle abnormalities, and mitotic arrest. Cancer Res. 2008 Aug 1;68(15):6181-9. PMID: 18676841.

 

Yoshida D, Hoshino S, Shimura T, et al. Drug-induced apoptosis by anti-microtubule agent, estramustine phosphate on human malignant glioma cell line, U87MG; in vitro study. J Neurooncol. 2000 Apr;47(2):133-40. PMID: 10982154.

 

Panda D, Miller HP, Islam K, et al. Stabilization of microtubule dynamics by estramustine by binding to a novel site in tubulin: a possible mechanistic basis for its antitumor action. Proc Natl Acad Sci U S A. 1997 Sep 30;94(20):10560-4. PMID: 9380674.

 

Punzi JS, Duax WL, Strong P, et al. Molecular conformation of estramustine and two analogues. Mol Pharmacol. 1992 Mar;41(3):569-76. PMID: 1545778.

" Not dangerous goods.

LKT E7579 Estramustine Phosphate Disodium 1 g 924.1 Nitrogen mustard and estradiol derivative; microtubule depolymerization inducer. 52205-73-9  ≥95% 564.35 C23H32Cl2NO6PNa2 CC12CCC3C(C1CCC2OP(=O)([O-])[O-])CCC4=C3C=CC(=C4)OC(=O)N(CCCl)CCCl.[Na+].[Na+] Ambient 4°C "Matsumoto K, Tanaka N, Hayakawa N, et al. Efficacy of estramustine phosphate sodium hydrate (EMP) monotherapy in castration-resistant prostate cancer patients: report of 102 cases and review of literature. Med Oncol. 2013 Dec;30(4):717. PMID: 24005812.

 

Mohan R, Panda D. Kinetic stabilization of microtubule dynamics by estramustine is associated with tubulin acetylation, spindle abnormalities, and mitotic arrest. Cancer Res. 2008 Aug 1;68(15):6181-9. PMID: 18676841.

 

Yoshida D, Hoshino S, Shimura T, et al. Drug-induced apoptosis by anti-microtubule agent, estramustine phosphate on human malignant glioma cell line, U87MG; in vitro study. J Neurooncol. 2000 Apr;47(2):133-40. PMID: 10982154.

 

Panda D, Miller HP, Islam K, et al. Stabilization of microtubule dynamics by estramustine by binding to a novel site in tubulin: a possible mechanistic basis for its antitumor action. Proc Natl Acad Sci U S A. 1997 Sep 30;94(20):10560-4. PMID: 9380674.

 

Punzi JS, Duax WL, Strong P, et al. Molecular conformation of estramustine and two analogues. Mol Pharmacol. 1992 Mar;41(3):569-76. PMID: 1545778.

" Not dangerous goods.

LKT E7658 Etoposide Phosphate 25 mg 84.3 Epipodophyllotoxin derivative; topoisomerase II inhibitor. Eposin, Etopophos, Vepesid, VP-16 117091-64-2  ≥98% 668.54 C29H33O16P CC1OCC2C(O1)C(C(C(O2)OC3C4COC(=O)C4C(C5=CC6=C(C=C35)OCO6)C7=CC(=C(C(=C7)OC)OP(=O)(O)O)OC)O)O Ambient -20°C Soluble in water "Johnson TS, Terrell CE, Millen SH, et al. Etoposide selectively ablates activated T cells to control the immunoregulatory disorder hemophagocytic lymphohistiocytosis. J Immunol. 2014 Jan 1;192(1):84-91. PMID: 24259502.

 

Mir Mohammadrezaei F, Mohseni kouchesfehani H, Montazeri H, et al. Signaling crosstalk of FHIT, CHK2 and p38 in etoposide induced growth inhibition in MCF-7 cells. Cell Signal. 2013 Jan;25(1):126-32. PMID: 23000346.

 

Yoo SH, Yoon YG, Lee JS, et al. Etoposide induces a mixed type of programmed cell death and overcomes the resistance conferred by Bcl-2 in Hep3B hepatoma cells. Int J Oncol. 2012 Oct;41(4):1443-54. PMID: 22895528.

 

Shin SY, Kim CG, Ko J, et al. Transcriptional and post-transcriptional regulation of the PKC delta gene by etoposide in L1210 murine leukemia cells: implication of PKC delta autoregulation. J Mol Biol. 2004 Jul 16;340(4):681-93. PMID: 15223313.

 

Mizumoto K, Rothman RJ, Farber JL. Programmed cell death (apoptosis) of mouse fibroblasts is induced by the topoisomerase II inhibitor etoposide. Mol Pharmacol. 1994 Nov;46(5):890-5. PMID: 7969076.

 

Nissen NI, Dombernowsky P, Hansen HH, et al. The epipodophyllotoxin derivatives VM-26 and VP-16-213, 1976-1979, a review. Recent Results Cancer Res. 1980;74:98-106. PMID: 7003663.

" Not dangerous goods.

LKT E7658 Etoposide Phosphate 100 mg 262.6 Epipodophyllotoxin derivative; topoisomerase II inhibitor. Eposin, Etopophos, Vepesid, VP-16 117091-64-2  ≥98% 668.54 C29H33O16P CC1OCC2C(O1)C(C(C(O2)OC3C4COC(=O)C4C(C5=CC6=C(C=C35)OCO6)C7=CC(=C(C(=C7)OC)OP(=O)(O)O)OC)O)O Ambient -20°C Soluble in water "Johnson TS, Terrell CE, Millen SH, et al. Etoposide selectively ablates activated T cells to control the immunoregulatory disorder hemophagocytic lymphohistiocytosis. J Immunol. 2014 Jan 1;192(1):84-91. PMID: 24259502.

 

Mir Mohammadrezaei F, Mohseni kouchesfehani H, Montazeri H, et al. Signaling crosstalk of FHIT, CHK2 and p38 in etoposide induced growth inhibition in MCF-7 cells. Cell Signal. 2013 Jan;25(1):126-32. PMID: 23000346.

 

Yoo SH, Yoon YG, Lee JS, et al. Etoposide induces a mixed type of programmed cell death and overcomes the resistance conferred by Bcl-2 in Hep3B hepatoma cells. Int J Oncol. 2012 Oct;41(4):1443-54. PMID: 22895528.

 

Shin SY, Kim CG, Ko J, et al. Transcriptional and post-transcriptional regulation of the PKC delta gene by etoposide in L1210 murine leukemia cells: implication of PKC delta autoregulation. J Mol Biol. 2004 Jul 16;340(4):681-93. PMID: 15223313.

 

Mizumoto K, Rothman RJ, Farber JL. Programmed cell death (apoptosis) of mouse fibroblasts is induced by the topoisomerase II inhibitor etoposide. Mol Pharmacol. 1994 Nov;46(5):890-5. PMID: 7969076.

 

Nissen NI, Dombernowsky P, Hansen HH, et al. The epipodophyllotoxin derivatives VM-26 and VP-16-213, 1976-1979, a review. Recent Results Cancer Res. 1980;74:98-106. PMID: 7003663.

" Not dangerous goods.

LKT E7658 Etoposide Phosphate 250 mg 600.1 Epipodophyllotoxin derivative; topoisomerase II inhibitor. Eposin, Etopophos, Vepesid, VP-16 117091-64-2  ≥98% 668.54 C29H33O16P CC1OCC2C(O1)C(C(C(O2)OC3C4COC(=O)C4C(C5=CC6=C(C=C35)OCO6)C7=CC(=C(C(=C7)OC)OP(=O)(O)O)OC)O)O Ambient -20°C Soluble in water "Johnson TS, Terrell CE, Millen SH, et al. Etoposide selectively ablates activated T cells to control the immunoregulatory disorder hemophagocytic lymphohistiocytosis. J Immunol. 2014 Jan 1;192(1):84-91. PMID: 24259502.

 

Mir Mohammadrezaei F, Mohseni kouchesfehani H, Montazeri H, et al. Signaling crosstalk of FHIT, CHK2 and p38 in etoposide induced growth inhibition in MCF-7 cells. Cell Signal. 2013 Jan;25(1):126-32. PMID: 23000346.

 

Yoo SH, Yoon YG, Lee JS, et al. Etoposide induces a mixed type of programmed cell death and overcomes the resistance conferred by Bcl-2 in Hep3B hepatoma cells. Int J Oncol. 2012 Oct;41(4):1443-54. PMID: 22895528.

 

Shin SY, Kim CG, Ko J, et al. Transcriptional and post-transcriptional regulation of the PKC delta gene by etoposide in L1210 murine leukemia cells: implication of PKC delta autoregulation. J Mol Biol. 2004 Jul 16;340(4):681-93. PMID: 15223313.

 

Mizumoto K, Rothman RJ, Farber JL. Programmed cell death (apoptosis) of mouse fibroblasts is induced by the topoisomerase II inhibitor etoposide. Mol Pharmacol. 1994 Nov;46(5):890-5. PMID: 7969076.

 

Nissen NI, Dombernowsky P, Hansen HH, et al. The epipodophyllotoxin derivatives VM-26 and VP-16-213, 1976-1979, a review. Recent Results Cancer Res. 1980;74:98-106. PMID: 7003663.

" Not dangerous goods.

LKT E7668 Etretinate 25 mg 84.3 Aromatic retinoid; RAR, RXR agonist. (all-E)-9-(4-Methoxy-2,3,6-trimethylphenyl)-3,7- dimethyl-2,4,6,8-nonatetraenoic acid ethyl ester Tegison; Tigason 54350-48-0 ≥98% 354.49 C25H30O3 CCOC(=O)C=C(C)C=CC=C(C)C=CC1=C(C(=C(C=C1C)OC)C)C Ambient -20°C "Burg G, Dummer R. Historical perspective on the use of retinoids in cutaneous T-cell lymphoma (CTCL). Clin Lymphoma. 2000 Nov;1 Suppl 1:S41-4. PMID: 11707863.

 

Saurat JH. Retinoids and psoriasis: novel issues in retinoid pharmacology and implications for psoriasis treatment. J Am Acad Dermatol. 1999 Sep;41(3 Pt 2):S2-6. PMID: 10459139.

" Repr., T "UN number: 3077      Class: 9     Packing Group: III

Proper shipping name: Environmentally hazardous substance, solid, n.o.s. (Etretinate)"

LKT E7668 Etretinate 100 mg 234.5 Aromatic retinoid; RAR, RXR agonist. (all-E)-9-(4-Methoxy-2,3,6-trimethylphenyl)-3,7- dimethyl-2,4,6,8-nonatetraenoic acid ethyl ester Tegison; Tigason 54350-48-0 ≥98% 354.49 C25H30O3 CCOC(=O)C=C(C)C=CC=C(C)C=CC1=C(C(=C(C=C1C)OC)C)C Ambient -20°C "Burg G, Dummer R. Historical perspective on the use of retinoids in cutaneous T-cell lymphoma (CTCL). Clin Lymphoma. 2000 Nov;1 Suppl 1:S41-4. PMID: 11707863.

 

Saurat JH. Retinoids and psoriasis: novel issues in retinoid pharmacology and implications for psoriasis treatment. J Am Acad Dermatol. 1999 Sep;41(3 Pt 2):S2-6. PMID: 10459139.

" Repr., T "UN number: 3077      Class: 9     Packing Group: III

Proper shipping name: Environmentally hazardous substance, solid, n.o.s. (Etretinate)"

LKT E7668 Etretinate 500 mg 750.1 Aromatic retinoid; RAR, RXR agonist. (all-E)-9-(4-Methoxy-2,3,6-trimethylphenyl)-3,7- dimethyl-2,4,6,8-nonatetraenoic acid ethyl ester Tegison; Tigason 54350-48-0 ≥98% 354.49 C25H30O3 CCOC(=O)C=C(C)C=CC=C(C)C=CC1=C(C(=C(C=C1C)OC)C)C Ambient -20°C "Burg G, Dummer R. Historical perspective on the use of retinoids in cutaneous T-cell lymphoma (CTCL). Clin Lymphoma. 2000 Nov;1 Suppl 1:S41-4. PMID: 11707863.

 

Saurat JH. Retinoids and psoriasis: novel issues in retinoid pharmacology and implications for psoriasis treatment. J Am Acad Dermatol. 1999 Sep;41(3 Pt 2):S2-6. PMID: 10459139.

" Repr., T "UN number: 3077      Class: 9     Packing Group: III

Proper shipping name: Environmentally hazardous substance, solid, n.o.s. (Etretinate)"

LKT E8419 Everolimus 1 mg 40.7 mTORC1 inhibitor. Certican 159351-69-6 ≥98% 958.22 C53H83NO14 CC1CCC2CC(C(=CC=CC=CC(CC(C(=O)C(C(C(=CC(C(=O)CC(OC(=O)C3CCCCN3C(=O)C(=O)C1(O2)O)C(C)CC4CCC(C(C4)OC)OCCO)C)C)O)OC)C)C)C)OC Ambient Ambient Insoluble in water.  Soluble in DMSO (30mg/mL), ethanol (7 mg/mL). "Sendur MA, Zengin N, Aksoy S, et al. Everolimus: a new hope for patients with breast cancer. Curr Med Res Opin. 2014 Jan;30(1):75-87. PMID: 24050600.

 

Cai Y, Xia Q, Su Q, et al. mTOR inhibitor RAD001 (everolimus) induces apoptotic, not autophagic cell death, in human nasopharyngeal carcinoma cells. Int J Mol Med. 2013 Apr;31(4):904-12. PMID: 23426850.

 

Hennig M, Bauer D, Wasmuth S, et al. Everolimus improves experimental autoimmune uveoretinitis. Exp Eye Res. 2012 Dec;105:43-52. PMID: 23059401.

 

Ramadan R, Faour D, Awad H, et al. Early treatment with everolimus exerts nephroprotective effect in rats with adriamycin-induced nephrotic syndrome. Nephrol Dial Transplant. 2012 Jun;27(6):2231-41. PMID: 22036940.

 

Wang ZG, Fukazawa T, Nishikawa T, et al. RAD001 offers a therapeutic intervention through inhibition of mTOR as a potential strategy for esophageal cancer. Oncol Rep. 2010 Apr;23(4):1167-72. PMID: 20204306.

 

Kahan BD, Koch SM. Current immunosuppressant regimens: considerations for critical care. Curr Opin Crit Care. 2001 Aug;7(4):242-50. PMID: 11571421.

" Xn, T Not dangerous goods

LKT E8419 Everolimus 5 mg 163.2 mTORC1 inhibitor. Certican 159351-69-6 ≥98% 958.22 C53H83NO14 CC1CCC2CC(C(=CC=CC=CC(CC(C(=O)C(C(C(=CC(C(=O)CC(OC(=O)C3CCCCN3C(=O)C(=O)C1(O2)O)C(C)CC4CCC(C(C4)OC)OCCO)C)C)O)OC)C)C)C)OC Ambient Ambient Insoluble in water.  Soluble in DMSO (30mg/mL), ethanol (7 mg/mL). "Sendur MA, Zengin N, Aksoy S, et al. Everolimus: a new hope for patients with breast cancer. Curr Med Res Opin. 2014 Jan;30(1):75-87. PMID: 24050600.

 

Cai Y, Xia Q, Su Q, et al. mTOR inhibitor RAD001 (everolimus) induces apoptotic, not autophagic cell death, in human nasopharyngeal carcinoma cells. Int J Mol Med. 2013 Apr;31(4):904-12. PMID: 23426850.

 

Hennig M, Bauer D, Wasmuth S, et al. Everolimus improves experimental autoimmune uveoretinitis. Exp Eye Res. 2012 Dec;105:43-52. PMID: 23059401.

 

Ramadan R, Faour D, Awad H, et al. Early treatment with everolimus exerts nephroprotective effect in rats with adriamycin-induced nephrotic syndrome. Nephrol Dial Transplant. 2012 Jun;27(6):2231-41. PMID: 22036940.

 

Wang ZG, Fukazawa T, Nishikawa T, et al. RAD001 offers a therapeutic intervention through inhibition of mTOR as a potential strategy for esophageal cancer. Oncol Rep. 2010 Apr;23(4):1167-72. PMID: 20204306.

 

Kahan BD, Koch SM. Current immunosuppressant regimens: considerations for critical care. Curr Opin Crit Care. 2001 Aug;7(4):242-50. PMID: 11571421.

" Xn, T Not dangerous goods

LKT E8419 Everolimus 25 mg 611.5 mTORC1 inhibitor. Certican 159351-69-6 ≥98% 958.22 C53H83NO14 CC1CCC2CC(C(=CC=CC=CC(CC(C(=O)C(C(C(=CC(C(=O)CC(OC(=O)C3CCCCN3C(=O)C(=O)C1(O2)O)C(C)CC4CCC(C(C4)OC)OCCO)C)C)O)OC)C)C)C)OC Ambient Ambient Insoluble in water.  Soluble in DMSO (30mg/mL), ethanol (7 mg/mL). "Sendur MA, Zengin N, Aksoy S, et al. Everolimus: a new hope for patients with breast cancer. Curr Med Res Opin. 2014 Jan;30(1):75-87. PMID: 24050600.

 

Cai Y, Xia Q, Su Q, et al. mTOR inhibitor RAD001 (everolimus) induces apoptotic, not autophagic cell death, in human nasopharyngeal carcinoma cells. Int J Mol Med. 2013 Apr;31(4):904-12. PMID: 23426850.

 

Hennig M, Bauer D, Wasmuth S, et al. Everolimus improves experimental autoimmune uveoretinitis. Exp Eye Res. 2012 Dec;105:43-52. PMID: 23059401.

 

Ramadan R, Faour D, Awad H, et al. Early treatment with everolimus exerts nephroprotective effect in rats with adriamycin-induced nephrotic syndrome. Nephrol Dial Transplant. 2012 Jun;27(6):2231-41. PMID: 22036940.

 

Wang ZG, Fukazawa T, Nishikawa T, et al. RAD001 offers a therapeutic intervention through inhibition of mTOR as a potential strategy for esophageal cancer. Oncol Rep. 2010 Apr;23(4):1167-72. PMID: 20204306.

 

Kahan BD, Koch SM. Current immunosuppressant regimens: considerations for critical care. Curr Opin Crit Care. 2001 Aug;7(4):242-50. PMID: 11571421.

" Xn, T Not dangerous goods

LKT E8657 Evodiamine 100 mg 67.9 Indole alkaloid found in Evodia rutaecarpa; topoisomerase I and II inhibitor. 518-17-2 ≥98% 303.36 C19H17N3O CN1C2C3=C(CCN2C(=O)C4=CC=CC=C41)C5=CC=CC=C5N3 Ambient Ambient "Zhang T, Qu S, Shi Q, et al. Evodiamine Induces Apoptosis and Enhances TRAIL-Induced Apoptosis in Human Bladder Cancer Cells through mTOR/S6K1-Mediated Downregulation of Mcl-1. Int J Mol Sci. 2014 Feb 21;15(2):3154-71. PMID: 24566141.

 

Wang T, Kusudo T, Takeuchi T, et al. Evodiamine inhibits insulin-stimulated mTOR-S6K activation and IRS1 serine phosphorylation in adipocytes and improves glucose tolerance in obese/diabetic mice. PLoS One. 2013 Dec 31;8(12):e83264. PMID: 24391749.

 

Dai JP, Li WZ, Zhao XF, et al. A drug screening method based on the autophagy pathway and studies of the mechanism of evodiamine against influenza A virus. PLoS One. 2012;7(8):e42706. PMID: 22900043.

 

Pan X, Hartley JM, Hartley JA, et al. Evodiamine, a dual catalytic inhibitor of type I and II topoisomerases, exhibits enhanced inhibition against camptothecin resistant cells. Phytomedicine. 2012 May 15;19(7):618-24. PMID: 22402246.

 

Shyu KG, Lin S, Lee CC, et al. Evodiamine inhibits in vitro angiogenesis: Implication for antitumorgenicity. Life Sci. 2006 Apr 4;78(19):2234-43. PMID: 16280136.

 

Wu CL, Hung CR, Chang FY, et al. Effects of evodiamine on gastrointestinal motility in male rats. Eur J Pharmacol. 2002 Dec 20;457(2-3):169-76. PMID: 12464363.

 

Sung B, Prasad S, Ravindran J, et al. Capsazepine, a TRPV1 antagonist, sensitizes colorectal cancer cells to apoptosis by TRAIL through ROS-JNK-CHOP-mediated upregulation of death receptors. Free Radic Biol Med. 2012 Nov 15;53(10):1977-1987. PMID: 22922338.

" T "UN number: 2811     Class: 6.1     Packing Group: III

Proper shipping name: Toxic solid, organic, n.o.s. (Evodiamine)"

LKT E8657 Evodiamine 250 mg 136 Indole alkaloid found in Evodia rutaecarpa; topoisomerase I and II inhibitor. 518-17-2 ≥98% 303.36 C19H17N3O CN1C2C3=C(CCN2C(=O)C4=CC=CC=C41)C5=CC=CC=C5N3 Ambient Ambient "Zhang T, Qu S, Shi Q, et al. Evodiamine Induces Apoptosis and Enhances TRAIL-Induced Apoptosis in Human Bladder Cancer Cells through mTOR/S6K1-Mediated Downregulation of Mcl-1. Int J Mol Sci. 2014 Feb 21;15(2):3154-71. PMID: 24566141.

 

Wang T, Kusudo T, Takeuchi T, et al. Evodiamine inhibits insulin-stimulated mTOR-S6K activation and IRS1 serine phosphorylation in adipocytes and improves glucose tolerance in obese/diabetic mice. PLoS One. 2013 Dec 31;8(12):e83264. PMID: 24391749.

 

Dai JP, Li WZ, Zhao XF, et al. A drug screening method based on the autophagy pathway and studies of the mechanism of evodiamine against influenza A virus. PLoS One. 2012;7(8):e42706. PMID: 22900043.

 

Pan X, Hartley JM, Hartley JA, et al. Evodiamine, a dual catalytic inhibitor of type I and II topoisomerases, exhibits enhanced inhibition against camptothecin resistant cells. Phytomedicine. 2012 May 15;19(7):618-24. PMID: 22402246.

 

Shyu KG, Lin S, Lee CC, et al. Evodiamine inhibits in vitro angiogenesis: Implication for antitumorgenicity. Life Sci. 2006 Apr 4;78(19):2234-43. PMID: 16280136.

 

Wu CL, Hung CR, Chang FY, et al. Effects of evodiamine on gastrointestinal motility in male rats. Eur J Pharmacol. 2002 Dec 20;457(2-3):169-76. PMID: 12464363.

 

Sung B, Prasad S, Ravindran J, et al. Capsazepine, a TRPV1 antagonist, sensitizes colorectal cancer cells to apoptosis by TRAIL through ROS-JNK-CHOP-mediated upregulation of death receptors. Free Radic Biol Med. 2012 Nov 15;53(10):1977-1987. PMID: 22922338.

" T "UN number: 2811     Class: 6.1     Packing Group: III

Proper shipping name: Toxic solid, organic, n.o.s. (Evodiamine)"

LKT E8657 Evodiamine 1 g 380.5 Indole alkaloid found in Evodia rutaecarpa; topoisomerase I and II inhibitor. 518-17-2 ≥98% 303.36 C19H17N3O CN1C2C3=C(CCN2C(=O)C4=CC=CC=C41)C5=CC=CC=C5N3 Ambient Ambient "Zhang T, Qu S, Shi Q, et al. Evodiamine Induces Apoptosis and Enhances TRAIL-Induced Apoptosis in Human Bladder Cancer Cells through mTOR/S6K1-Mediated Downregulation of Mcl-1. Int J Mol Sci. 2014 Feb 21;15(2):3154-71. PMID: 24566141.

 

Wang T, Kusudo T, Takeuchi T, et al. Evodiamine inhibits insulin-stimulated mTOR-S6K activation and IRS1 serine phosphorylation in adipocytes and improves glucose tolerance in obese/diabetic mice. PLoS One. 2013 Dec 31;8(12):e83264. PMID: 24391749.

 

Dai JP, Li WZ, Zhao XF, et al. A drug screening method based on the autophagy pathway and studies of the mechanism of evodiamine against influenza A virus. PLoS One. 2012;7(8):e42706. PMID: 22900043.

 

Pan X, Hartley JM, Hartley JA, et al. Evodiamine, a dual catalytic inhibitor of type I and II topoisomerases, exhibits enhanced inhibition against camptothecin resistant cells. Phytomedicine. 2012 May 15;19(7):618-24. PMID: 22402246.

 

Shyu KG, Lin S, Lee CC, et al. Evodiamine inhibits in vitro angiogenesis: Implication for antitumorgenicity. Life Sci. 2006 Apr 4;78(19):2234-43. PMID: 16280136.

 

Wu CL, Hung CR, Chang FY, et al. Effects of evodiamine on gastrointestinal motility in male rats. Eur J Pharmacol. 2002 Dec 20;457(2-3):169-76. PMID: 12464363.

 

Sung B, Prasad S, Ravindran J, et al. Capsazepine, a TRPV1 antagonist, sensitizes colorectal cancer cells to apoptosis by TRAIL through ROS-JNK-CHOP-mediated upregulation of death receptors. Free Radic Biol Med. 2012 Nov 15;53(10):1977-1987. PMID: 22922338.

" T "UN number: 2811     Class: 6.1     Packing Group: III

Proper shipping name: Toxic solid, organic, n.o.s. (Evodiamine)"

LKT E9317 Exemestane 25 mg 67.9 Aromatase inhibitor. 6-Methyleneandrosta-1,4-diene-3,17-dione Aromasin; FCE-24304 107868-30-4 ≥98% 296.4 C20H24O2 CC12CCC3C(C1CCC2=O)CC(=C)C4=CC(=O)C=CC34C Ambient Ambient Soluble in methanol, ethanol (15 mg/mL), DMSO (54mg/mL) or dimethylformamide. Insoluble in water. "Amaral C, Borges M, Melo S, et al. Apoptosis and autophagy in breast cancer cells following exemestane treatment. PLoS One. 2012;7(8):e42398. PMID: 22912703.

 

Hong Y, Rashid R, Chen S. Binding features of steroidal and nonsteroidal inhibitors. Steroids. 2011 Jul;76(8):802-6. PMID: 21420422.

 

Bertelli G, Hall E, Ireland E, et al. Long-term endometrial effects in postmenopausal women with early breast cancer participating in the Intergroup Exemestane Study (IES)--a randomised controlled trial of exemestane versus continued tamoxifen after 2-3 years tamoxifen. Ann Oncol. 2010 Mar;21(3):498-505. PMID: 19717534.

" N Not dangerous goods.

LKT E9317 Exemestane 100 mg 203.8 Aromatase inhibitor. 6-Methyleneandrosta-1,4-diene-3,17-dione Aromasin; FCE-24304 107868-30-4 ≥98% 296.4 C20H24O2 CC12CCC3C(C1CCC2=O)CC(=C)C4=CC(=O)C=CC34C Ambient Ambient Soluble in methanol, ethanol (15 mg/mL), DMSO (54mg/mL) or dimethylformamide. Insoluble in water. "Amaral C, Borges M, Melo S, et al. Apoptosis and autophagy in breast cancer cells following exemestane treatment. PLoS One. 2012;7(8):e42398. PMID: 22912703.

 

Hong Y, Rashid R, Chen S. Binding features of steroidal and nonsteroidal inhibitors. Steroids. 2011 Jul;76(8):802-6. PMID: 21420422.

 

Bertelli G, Hall E, Ireland E, et al. Long-term endometrial effects in postmenopausal women with early breast cancer participating in the Intergroup Exemestane Study (IES)--a randomised controlled trial of exemestane versus continued tamoxifen after 2-3 years tamoxifen. Ann Oncol. 2010 Mar;21(3):498-505. PMID: 19717534.

" N Not dangerous goods.

LKT E9416 Exendin-3 0.5 mg 468.2 Peptide, GLP-1 analog found in Heloderma; GLP-1 agonist. 130391-54-7 ≥95% 4202.66 C184H282N50O61S CCC(C)C(C(=O)NC(CCC(=O)O)C(=O)NC(CC1=CNC2=CC=CC=C21)C(=O)NC(CC(C)C)C(=O)NC(CCCCN)C(=O)NC(CC(=O)N)C(=O)NCC(=O)NCC(=O)N3CCCC3C(=O)NC(CO)C(=O)NC(CO)C(=O)NCC(=O)NC(C)C(=O)N4CCCC4C(=O)N5CCCC5C(=O)N6CCCC6C(=O)NC(CO)C(=O)N)NC(=O)C(CC7=CC=CC=C7)NC(=O)C(CC(C)C)NC(=O)C(CCCNC(=N)N)NC(=O)C(C(C)C)NC(=O)C(C)NC(=O)C(CCC(=O)O)NC(=O)C(CCC(=O)O)NC(=O)C(CCC(=O)O)NC(=O)C(CCSC)NC(=O)C(CCC(=O)N)NC(=O)C(CCCCN)NC(=O)C(CO)NC(=O)C(CC(C)C)NC(=O)C(CC(=O)O)NC(=O)C(CO)NC(=O)C(C(C)O)NC(=O)C(CC8=CC=CC=C8)NC(=O)C(C(C)O)NC(=O)CNC(=O)C(CC(=O)O)NC(=O)C(CO)NC(=O)C(CC9=CNC=N9)N Ambient -20°C "Zhang Y, Chen W. Radiolabeled glucagon-like peptide-1 analogues: a new pancreatic β-cell imaging agent. Nucl Med Commun. 2012 Mar;33(3):223-7.PMID: 22262216.

 

Eng J, Andrews PC, Kleinman WA, et al. Purification and structure of exendin-3, a new pancreatic secretagogue isolated from Heloderma horridum venom. J Biol Chem. 1990 Nov 25;265(33):20259-62. PMID: 1700785.

" Not dangerous goods.

LKT E9416 Exendin-3 1 mg 795.1 Peptide, GLP-1 analog found in Heloderma; GLP-1 agonist. 130391-54-7 ≥95% 4202.66 C184H282N50O61S CCC(C)C(C(=O)NC(CCC(=O)O)C(=O)NC(CC1=CNC2=CC=CC=C21)C(=O)NC(CC(C)C)C(=O)NC(CCCCN)C(=O)NC(CC(=O)N)C(=O)NCC(=O)NCC(=O)N3CCCC3C(=O)NC(CO)C(=O)NC(CO)C(=O)NCC(=O)NC(C)C(=O)N4CCCC4C(=O)N5CCCC5C(=O)N6CCCC6C(=O)NC(CO)C(=O)N)NC(=O)C(CC7=CC=CC=C7)NC(=O)C(CC(C)C)NC(=O)C(CCCNC(=N)N)NC(=O)C(C(C)C)NC(=O)C(C)NC(=O)C(CCC(=O)O)NC(=O)C(CCC(=O)O)NC(=O)C(CCC(=O)O)NC(=O)C(CCSC)NC(=O)C(CCC(=O)N)NC(=O)C(CCCCN)NC(=O)C(CO)NC(=O)C(CC(C)C)NC(=O)C(CC(=O)O)NC(=O)C(CO)NC(=O)C(C(C)O)NC(=O)C(CC8=CC=CC=C8)NC(=O)C(C(C)O)NC(=O)CNC(=O)C(CC(=O)O)NC(=O)C(CO)NC(=O)C(CC9=CNC=N9)N Ambient -20°C "Zhang Y, Chen W. Radiolabeled glucagon-like peptide-1 analogues: a new pancreatic β-cell imaging agent. Nucl Med Commun. 2012 Mar;33(3):223-7.PMID: 22262216.

 

Eng J, Andrews PC, Kleinman WA, et al. Purification and structure of exendin-3, a new pancreatic secretagogue isolated from Heloderma horridum venom. J Biol Chem. 1990 Nov 25;265(33):20259-62. PMID: 1700785.

" Not dangerous goods.

LKT E9416 Exendin-3 2.5 mg 1404.2 Peptide, GLP-1 analog found in Heloderma; GLP-1 agonist. 130391-54-7 ≥95% 4202.66 C184H282N50O61S CCC(C)C(C(=O)NC(CCC(=O)O)C(=O)NC(CC1=CNC2=CC=CC=C21)C(=O)NC(CC(C)C)C(=O)NC(CCCCN)C(=O)NC(CC(=O)N)C(=O)NCC(=O)NCC(=O)N3CCCC3C(=O)NC(CO)C(=O)NC(CO)C(=O)NCC(=O)NC(C)C(=O)N4CCCC4C(=O)N5CCCC5C(=O)N6CCCC6C(=O)NC(CO)C(=O)N)NC(=O)C(CC7=CC=CC=C7)NC(=O)C(CC(C)C)NC(=O)C(CCCNC(=N)N)NC(=O)C(C(C)C)NC(=O)C(C)NC(=O)C(CCC(=O)O)NC(=O)C(CCC(=O)O)NC(=O)C(CCC(=O)O)NC(=O)C(CCSC)NC(=O)C(CCC(=O)N)NC(=O)C(CCCCN)NC(=O)C(CO)NC(=O)C(CC(C)C)NC(=O)C(CC(=O)O)NC(=O)C(CO)NC(=O)C(C(C)O)NC(=O)C(CC8=CC=CC=C8)NC(=O)C(C(C)O)NC(=O)CNC(=O)C(CC(=O)O)NC(=O)C(CO)NC(=O)C(CC9=CNC=N9)N Ambient -20°C "Zhang Y, Chen W. Radiolabeled glucagon-like peptide-1 analogues: a new pancreatic β-cell imaging agent. Nucl Med Commun. 2012 Mar;33(3):223-7.PMID: 22262216.

 

Eng J, Andrews PC, Kleinman WA, et al. Purification and structure of exendin-3, a new pancreatic secretagogue isolated from Heloderma horridum venom. J Biol Chem. 1990 Nov 25;265(33):20259-62. PMID: 1700785.

" Not dangerous goods.

LKT E9417 Exendin-4 0.5 mg 468.2 Peptide, GLP-1 analog found in Heloderma; GLP-1 agonist. Exenatide, Exendin 4 (Heloderma suspectum) 141758-74-9 ≥95% 4186.03 C184H282N50O60S CCC(C)C(C(=O)NC(CCC(=O)O)C(=O)NC(CC1=CNC2=CC=CC=C21)C(=O)NC(CC(C)C)C(=O)NC(CCCCN)C(=O)NC(CC(=O)N)C(=O)NCC(=O)NCC(=O)N3CCCC3C(=O)NC(CO)C(=O)NC(CO)C(=O)NCC(=O)NC(C)C(=O)N4CCCC4C(=O)N5CCCC5C(=O)N6CCCC6C(=O)NC(CO)C(=O)N)NC(=O)C(CC7=CC=CC=C7)NC(=O)C(CC(C)C)NC(=O)C(CCCNC(=N)N)NC(=O)C(C(C)C)NC(=O)C(C)NC(=O)C(CCC(=O)O)NC(=O)C(CCC(=O)O)NC(=O)C(CCC(=O)O)NC(=O)C(CCSC)NC(=O)C(CCC(=O)N)NC(=O)C(CCCCN)NC(=O)C(CO)NC(=O)C(CC(C)C)NC(=O)C(CC(=O)O)NC(=O)C(CO)NC(=O)C(C(C)O)NC(=O)C(CC8=CC=CC=C8)NC(=O)C(C(C)O)NC(=O)CNC(=O)C(CCC(=O)O)NC(=O)CNC(=O)C(CC9=CNC=N9)N Ambient -20°C "Xu WW, Guan MP, Zheng ZJ, et al. Exendin-4 Alleviates High Glucose-Induced Rat Mesangial Cell Dysfunction through the AMPK Pathway. Cell Physiol Biochem. 2014;33(2):423-32. PMID: 24556697.

 

Hu G, Zhang Y, Jiang H, et al. Exendin-4 attenuates myocardial ischemia and reperfusion injury by inhibiting high mobility group box 1 protein expression. Cardiol J. 2013;20(6):600-4. PMID: 24338536.

 

Ma GF, Chen S, Yin L, et al. Exendin-4 ameliorates oxidized-LDL-induced inhibition of macrophage migration in vitro via the NF-κB pathway. Acta Pharmacol Sin. 2014 Feb;35(2):195-202. PMID: 24335838.

 

Li Z, Zhou Z, Huang G, et al. Exendin-4 protects mitochondria from reactive oxygen species induced apoptosis in pancreatic Beta cells. PLoS One. 2013 Oct 24;8(10):e76172. PMID: 24204601.

" Not dangerous goods.

LKT E9417 Exendin-4 1 mg 795.1 Peptide, GLP-1 analog found in Heloderma; GLP-1 agonist. Exenatide, Exendin 4 (Heloderma suspectum) 141758-74-9 ≥95% 4186.03 C184H282N50O60S CCC(C)C(C(=O)NC(CCC(=O)O)C(=O)NC(CC1=CNC2=CC=CC=C21)C(=O)NC(CC(C)C)C(=O)NC(CCCCN)C(=O)NC(CC(=O)N)C(=O)NCC(=O)NCC(=O)N3CCCC3C(=O)NC(CO)C(=O)NC(CO)C(=O)NCC(=O)NC(C)C(=O)N4CCCC4C(=O)N5CCCC5C(=O)N6CCCC6C(=O)NC(CO)C(=O)N)NC(=O)C(CC7=CC=CC=C7)NC(=O)C(CC(C)C)NC(=O)C(CCCNC(=N)N)NC(=O)C(C(C)C)NC(=O)C(C)NC(=O)C(CCC(=O)O)NC(=O)C(CCC(=O)O)NC(=O)C(CCC(=O)O)NC(=O)C(CCSC)NC(=O)C(CCC(=O)N)NC(=O)C(CCCCN)NC(=O)C(CO)NC(=O)C(CC(C)C)NC(=O)C(CC(=O)O)NC(=O)C(CO)NC(=O)C(C(C)O)NC(=O)C(CC8=CC=CC=C8)NC(=O)C(C(C)O)NC(=O)CNC(=O)C(CCC(=O)O)NC(=O)CNC(=O)C(CC9=CNC=N9)N Ambient -20°C "Xu WW, Guan MP, Zheng ZJ, et al. Exendin-4 Alleviates High Glucose-Induced Rat Mesangial Cell Dysfunction through the AMPK Pathway. Cell Physiol Biochem. 2014;33(2):423-32. PMID: 24556697.

 

Hu G, Zhang Y, Jiang H, et al. Exendin-4 attenuates myocardial ischemia and reperfusion injury by inhibiting high mobility group box 1 protein expression. Cardiol J. 2013;20(6):600-4. PMID: 24338536.

 

Ma GF, Chen S, Yin L, et al. Exendin-4 ameliorates oxidized-LDL-induced inhibition of macrophage migration in vitro via the NF-κB pathway. Acta Pharmacol Sin. 2014 Feb;35(2):195-202. PMID: 24335838.

 

Li Z, Zhou Z, Huang G, et al. Exendin-4 protects mitochondria from reactive oxygen species induced apoptosis in pancreatic Beta cells. PLoS One. 2013 Oct 24;8(10):e76172. PMID: 24204601.

" Not dangerous goods.

LKT E9417 Exendin-4 2.5 mg 1404.2 Peptide, GLP-1 analog found in Heloderma; GLP-1 agonist. Exenatide, Exendin 4 (Heloderma suspectum) 141758-74-9 ≥95% 4186.03 C184H282N50O60S CCC(C)C(C(=O)NC(CCC(=O)O)C(=O)NC(CC1=CNC2=CC=CC=C21)C(=O)NC(CC(C)C)C(=O)NC(CCCCN)C(=O)NC(CC(=O)N)C(=O)NCC(=O)NCC(=O)N3CCCC3C(=O)NC(CO)C(=O)NC(CO)C(=O)NCC(=O)NC(C)C(=O)N4CCCC4C(=O)N5CCCC5C(=O)N6CCCC6C(=O)NC(CO)C(=O)N)NC(=O)C(CC7=CC=CC=C7)NC(=O)C(CC(C)C)NC(=O)C(CCCNC(=N)N)NC(=O)C(C(C)C)NC(=O)C(C)NC(=O)C(CCC(=O)O)NC(=O)C(CCC(=O)O)NC(=O)C(CCC(=O)O)NC(=O)C(CCSC)NC(=O)C(CCC(=O)N)NC(=O)C(CCCCN)NC(=O)C(CO)NC(=O)C(CC(C)C)NC(=O)C(CC(=O)O)NC(=O)C(CO)NC(=O)C(C(C)O)NC(=O)C(CC8=CC=CC=C8)NC(=O)C(C(C)O)NC(=O)CNC(=O)C(CCC(=O)O)NC(=O)CNC(=O)C(CC9=CNC=N9)N Ambient -20°C "Xu WW, Guan MP, Zheng ZJ, et al. Exendin-4 Alleviates High Glucose-Induced Rat Mesangial Cell Dysfunction through the AMPK Pathway. Cell Physiol Biochem. 2014;33(2):423-32. PMID: 24556697.

 

Hu G, Zhang Y, Jiang H, et al. Exendin-4 attenuates myocardial ischemia and reperfusion injury by inhibiting high mobility group box 1 protein expression. Cardiol J. 2013;20(6):600-4. PMID: 24338536.

 

Ma GF, Chen S, Yin L, et al. Exendin-4 ameliorates oxidized-LDL-induced inhibition of macrophage migration in vitro via the NF-κB pathway. Acta Pharmacol Sin. 2014 Feb;35(2):195-202. PMID: 24335838.

 

Li Z, Zhou Z, Huang G, et al. Exendin-4 protects mitochondria from reactive oxygen species induced apoptosis in pancreatic Beta cells. PLoS One. 2013 Oct 24;8(10):e76172. PMID: 24204601.

" Not dangerous goods.

LKT E9418 Exendin 3 (9-39) 0.5 mg 600.1 Peptide, GLP-1 analog found in Heloderma; GLP-1 antagonist. 9-39-Exendin 3(Heloderma horridum) (9CI); Exendin 3 (9-39) 133514-43-9 ≥95% 3369.83 C149H234N40O47S CCC(C)C(C(=O)NC(CCC(=O)O)C(=O)NC(CC1=CNC2=CC=CC=C21)C(=O)NC(CC(C)C)C(=O)NC(CCCCN)C(=O)NC(CC(=O)N)C(=O)NCC(=O)NCC(=O)N3CCCC3C(=O)NC(CO)C(=O)NC(CO)C(=O)NCC(=O)NC(C)C(=O)N4CCCC4C(=O)N5CCCC5C(=O)N6CCCC6C(=O)NC(CO)C(=O)N)NC(=O)C(CC7=CC=CC=C7)NC(=O)C(CC(C)C)NC(=O)C(CCCNC(=N)N)NC(=O)C(C(C)C)NC(=O)C(C)NC(=O)C(CCC(=O)O)NC(=O)C(CCC(=O)O)NC(=O)C(CCC(=O)O)NC(=O)C(CCSC)NC(=O)C(CCC(=O)N)NC(=O)C(CCCCN)NC(=O)C(CO)NC(=O)C(CC(C)C)NC(=O)C(CC(=O)O)N Ambient -20°C "Amato A, Baldassano S, Liotta R, et al. Exogenous glucagon-like peptide-1 reduces contractions in human colon circular muscle. J Endocrinol. 2014 Jan 17. [Epub ahead of print]. PMID: 24443715.

 

Hu G, Zhang Y, Jiang H, et al. Exendin-4 attenuates myocardial ischemia and reperfusion injury by inhibiting high mobility group box 1 protein expression. Cardiol J. 2013;20(6):600-4. PMID: 24338536.

" Not dangerous goods.

LKT E9418 Exendin 3 (9-39) 1 mg 1020.2 Peptide, GLP-1 analog found in Heloderma; GLP-1 antagonist. 9-39-Exendin 3(Heloderma horridum) (9CI); Exendin 3 (9-39) 133514-43-9 ≥95% 3369.83 C149H234N40O47S CCC(C)C(C(=O)NC(CCC(=O)O)C(=O)NC(CC1=CNC2=CC=CC=C21)C(=O)NC(CC(C)C)C(=O)NC(CCCCN)C(=O)NC(CC(=O)N)C(=O)NCC(=O)NCC(=O)N3CCCC3C(=O)NC(CO)C(=O)NC(CO)C(=O)NCC(=O)NC(C)C(=O)N4CCCC4C(=O)N5CCCC5C(=O)N6CCCC6C(=O)NC(CO)C(=O)N)NC(=O)C(CC7=CC=CC=C7)NC(=O)C(CC(C)C)NC(=O)C(CCCNC(=N)N)NC(=O)C(C(C)C)NC(=O)C(C)NC(=O)C(CCC(=O)O)NC(=O)C(CCC(=O)O)NC(=O)C(CCC(=O)O)NC(=O)C(CCSC)NC(=O)C(CCC(=O)N)NC(=O)C(CCCCN)NC(=O)C(CO)NC(=O)C(CC(C)C)NC(=O)C(CC(=O)O)N Ambient -20°C "Amato A, Baldassano S, Liotta R, et al. Exogenous glucagon-like peptide-1 reduces contractions in human colon circular muscle. J Endocrinol. 2014 Jan 17. [Epub ahead of print]. PMID: 24443715.

 

Hu G, Zhang Y, Jiang H, et al. Exendin-4 attenuates myocardial ischemia and reperfusion injury by inhibiting high mobility group box 1 protein expression. Cardiol J. 2013;20(6):600-4. PMID: 24338536.

" Not dangerous goods.

LKT E9418 Exendin 3 (9-39) 2.5 mg 1800.2 Peptide, GLP-1 analog found in Heloderma; GLP-1 antagonist. 9-39-Exendin 3(Heloderma horridum) (9CI); Exendin 3 (9-39) 133514-43-9 ≥95% 3369.83 C149H234N40O47S CCC(C)C(C(=O)NC(CCC(=O)O)C(=O)NC(CC1=CNC2=CC=CC=C21)C(=O)NC(CC(C)C)C(=O)NC(CCCCN)C(=O)NC(CC(=O)N)C(=O)NCC(=O)NCC(=O)N3CCCC3C(=O)NC(CO)C(=O)NC(CO)C(=O)NCC(=O)NC(C)C(=O)N4CCCC4C(=O)N5CCCC5C(=O)N6CCCC6C(=O)NC(CO)C(=O)N)NC(=O)C(CC7=CC=CC=C7)NC(=O)C(CC(C)C)NC(=O)C(CCCNC(=N)N)NC(=O)C(C(C)C)NC(=O)C(C)NC(=O)C(CCC(=O)O)NC(=O)C(CCC(=O)O)NC(=O)C(CCC(=O)O)NC(=O)C(CCSC)NC(=O)C(CCC(=O)N)NC(=O)C(CCCCN)NC(=O)C(CO)NC(=O)C(CC(C)C)NC(=O)C(CC(=O)O)N Ambient -20°C "Amato A, Baldassano S, Liotta R, et al. Exogenous glucagon-like peptide-1 reduces contractions in human colon circular muscle. J Endocrinol. 2014 Jan 17. [Epub ahead of print]. PMID: 24443715.

 

Hu G, Zhang Y, Jiang H, et al. Exendin-4 attenuates myocardial ischemia and reperfusion injury by inhibiting high mobility group box 1 protein expression. Cardiol J. 2013;20(6):600-4. PMID: 24338536.

" Not dangerous goods.

LKT E9819 Ezetimibe 25 mg 67.9 NPC1L1 inhibitor. 163222-33-1 ≥98% 409.43 C24H21F2NO3 C1=CC(=CC=C1C2C(C(=O)N2C3=CC=C(C=C3)F)CCC(C4=CC=C(C=C4)F)O)O Ambient Ambient "

Yamamura T, Ohsaki Y, Suzuki M, et al. Inhibition of NPC1L1 by ezetimibe activates autophagy in human hepatocyte and reduces mutant α1-antitrypsin Z deposition. Hepatology. 2013 Nov 9. [Epub ahead of print]. PMID: 24214142.

 

Wang X, Sugimoto K, Fujisawa T, et al. Novel effect of ezetimibe to inhibit the development of non-alcoholic fatty liver disease in Fatty Liver Shionogi mouse. Hepatol Res. 2014 Jan;44(1):102-13. PMID: 23510093.

 

Muñoz-Pacheco P, Ortega-Hernández A, Miana M, et al. Ezetimibe inhibits PMA-induced monocyte/macrophage differentiation by altering microRNA expression: a novel anti-atherosclerotic mechanism. Pharmacol Res. 2012 Dec;66(6):536-43. PMID: 22989505.

 

Phan BA, Dayspring TD, Toth PP. Ezetimibe therapy: mechanism of action and clinical update. Vasc Health Risk Manag. 2012;8:415-27. PMID: 22910633.

 

Garcia-Calvo M, Lisnock J, Bull HG, et al. The target of ezetimibe is Niemann-Pick C1-Like 1 (NPC1L1). Proc Natl Acad Sci U S A. 2005 Jun 7;102(23):8132-7. PMID: 15928087.

" Xi Not dangerous goods.

LKT E9819 Ezetimibe 100 mg 163.2 NPC1L1 inhibitor. 163222-33-1 ≥98% 409.43 C24H21F2NO3 C1=CC(=CC=C1C2C(C(=O)N2C3=CC=C(C=C3)F)CCC(C4=CC=C(C=C4)F)O)O Ambient Ambient "

Yamamura T, Ohsaki Y, Suzuki M, et al. Inhibition of NPC1L1 by ezetimibe activates autophagy in human hepatocyte and reduces mutant α1-antitrypsin Z deposition. Hepatology. 2013 Nov 9. [Epub ahead of print]. PMID: 24214142.

 

Wang X, Sugimoto K, Fujisawa T, et al. Novel effect of ezetimibe to inhibit the development of non-alcoholic fatty liver disease in Fatty Liver Shionogi mouse. Hepatol Res. 2014 Jan;44(1):102-13. PMID: 23510093.

 

Muñoz-Pacheco P, Ortega-Hernández A, Miana M, et al. Ezetimibe inhibits PMA-induced monocyte/macrophage differentiation by altering microRNA expression: a novel anti-atherosclerotic mechanism. Pharmacol Res. 2012 Dec;66(6):536-43. PMID: 22989505.

 

Phan BA, Dayspring TD, Toth PP. Ezetimibe therapy: mechanism of action and clinical update. Vasc Health Risk Manag. 2012;8:415-27. PMID: 22910633.

 

Garcia-Calvo M, Lisnock J, Bull HG, et al. The target of ezetimibe is Niemann-Pick C1-Like 1 (NPC1L1). Proc Natl Acad Sci U S A. 2005 Jun 7;102(23):8132-7. PMID: 15928087.

" Xi Not dangerous goods.

LKT E9819 Ezetimibe 250 mg 339.8 NPC1L1 inhibitor. 163222-33-1 ≥98% 409.43 C24H21F2NO3 C1=CC(=CC=C1C2C(C(=O)N2C3=CC=C(C=C3)F)CCC(C4=CC=C(C=C4)F)O)O Ambient Ambient "

Yamamura T, Ohsaki Y, Suzuki M, et al. Inhibition of NPC1L1 by ezetimibe activates autophagy in human hepatocyte and reduces mutant α1-antitrypsin Z deposition. Hepatology. 2013 Nov 9. [Epub ahead of print]. PMID: 24214142.

 

Wang X, Sugimoto K, Fujisawa T, et al. Novel effect of ezetimibe to inhibit the development of non-alcoholic fatty liver disease in Fatty Liver Shionogi mouse. Hepatol Res. 2014 Jan;44(1):102-13. PMID: 23510093.

 

Muñoz-Pacheco P, Ortega-Hernández A, Miana M, et al. Ezetimibe inhibits PMA-induced monocyte/macrophage differentiation by altering microRNA expression: a novel anti-atherosclerotic mechanism. Pharmacol Res. 2012 Dec;66(6):536-43. PMID: 22989505.

 

Phan BA, Dayspring TD, Toth PP. Ezetimibe therapy: mechanism of action and clinical update. Vasc Health Risk Manag. 2012;8:415-27. PMID: 22910633.

 

Garcia-Calvo M, Lisnock J, Bull HG, et al. The target of ezetimibe is Niemann-Pick C1-Like 1 (NPC1L1). Proc Natl Acad Sci U S A. 2005 Jun 7;102(23):8132-7. PMID: 15928087.

" Xi Not dangerous goods.

LKT K0030 Kahweol 10 mg 133.2 Diterpene found in coffee beans. 6894-43-5 ≥97% 314.42 C20H26O3 CC12C=CC3=C(C1CCC45C2CCC(C4)C(C5)(CO)O)C=CO3 Blue Ice -20°C Ethanol 5 mg/mL, DMF 5 mg/mL, DMSO 3 mg/mL. "Chae JI, Jeon YJ, Shim JH. Anti-Proliferative Properties of Kahweol in Oral Squamous Cancer Through the Regulation Specificity Protein 1. Phytother Res. 2014 Sep 8. [Epub ahead of print]. PMID: 25196544.

 

Wu KC, McDonald PR, Liu J, et al. Screening of natural compounds as activators of the keap1-nrf2 pathway. Planta Med. 2014 Jan;80(1):97-104. PMID: 24310212.

 

Fumimoto R, Sakai E, Yamaguchi Y, et al. The coffee diterpene kahweol prevents osteoclastogenesis via impairment of NFATc1 expression and blocking of Erk phosphorylation. J Pharmacol Sci. 2012;118(4):479-86. PMID: 22447306.

 

Cárdenas C, Quesada AR, Medina MA. Anti-angiogenic and anti-inflammatory properties of kahweol, a coffee diterpene. PLoS One. 2011;6(8):e23407. Erratum in: PLoS One. 2011;6(11). PMID: 21858104.

 

Lee KJ, Jeong HG. Protective effects of kahweol and cafestol against hydrogen peroxide-induced oxidative stress and DNA damage. Toxicol Lett. 2007 Sep 10;173(2):80-7. PMID: 17689207.

 

Cavin C, Mace K, Offord EA, et al. Protective effects of coffee diterpenes against aflatoxin B1-induced genotoxicity: mechanisms in rat and human cells. Food Chem Toxicol. 2001 Jun;39(6):549-56. PMID: 11346484.

" Not dangerous goods.

LKT K0030 Kahweol 25 mg 261.2 Diterpene found in coffee beans. 6894-43-5 ≥97% 314.42 C20H26O3 CC12C=CC3=C(C1CCC45C2CCC(C4)C(C5)(CO)O)C=CO3 Blue Ice -20°C Ethanol 5 mg/mL, DMF 5 mg/mL, DMSO 3 mg/mL. "Chae JI, Jeon YJ, Shim JH. Anti-Proliferative Properties of Kahweol in Oral Squamous Cancer Through the Regulation Specificity Protein 1. Phytother Res. 2014 Sep 8. [Epub ahead of print]. PMID: 25196544.

 

Wu KC, McDonald PR, Liu J, et al. Screening of natural compounds as activators of the keap1-nrf2 pathway. Planta Med. 2014 Jan;80(1):97-104. PMID: 24310212.

 

Fumimoto R, Sakai E, Yamaguchi Y, et al. The coffee diterpene kahweol prevents osteoclastogenesis via impairment of NFATc1 expression and blocking of Erk phosphorylation. J Pharmacol Sci. 2012;118(4):479-86. PMID: 22447306.

 

Cárdenas C, Quesada AR, Medina MA. Anti-angiogenic and anti-inflammatory properties of kahweol, a coffee diterpene. PLoS One. 2011;6(8):e23407. Erratum in: PLoS One. 2011;6(11). PMID: 21858104.

 

Lee KJ, Jeong HG. Protective effects of kahweol and cafestol against hydrogen peroxide-induced oxidative stress and DNA damage. Toxicol Lett. 2007 Sep 10;173(2):80-7. PMID: 17689207.

 

Cavin C, Mace K, Offord EA, et al. Protective effects of coffee diterpenes against aflatoxin B1-induced genotoxicity: mechanisms in rat and human cells. Food Chem Toxicol. 2001 Jun;39(6):549-56. PMID: 11346484.

" Not dangerous goods.

LKT K0030 Kahweol 100 mg 582.3 Diterpene found in coffee beans. 6894-43-5 ≥97% 314.42 C20H26O3 CC12C=CC3=C(C1CCC45C2CCC(C4)C(C5)(CO)O)C=CO3 Blue Ice -20°C Ethanol 5 mg/mL, DMF 5 mg/mL, DMSO 3 mg/mL. "Chae JI, Jeon YJ, Shim JH. Anti-Proliferative Properties of Kahweol in Oral Squamous Cancer Through the Regulation Specificity Protein 1. Phytother Res. 2014 Sep 8. [Epub ahead of print]. PMID: 25196544.

 

Wu KC, McDonald PR, Liu J, et al. Screening of natural compounds as activators of the keap1-nrf2 pathway. Planta Med. 2014 Jan;80(1):97-104. PMID: 24310212.

 

Fumimoto R, Sakai E, Yamaguchi Y, et al. The coffee diterpene kahweol prevents osteoclastogenesis via impairment of NFATc1 expression and blocking of Erk phosphorylation. J Pharmacol Sci. 2012;118(4):479-86. PMID: 22447306.

 

Cárdenas C, Quesada AR, Medina MA. Anti-angiogenic and anti-inflammatory properties of kahweol, a coffee diterpene. PLoS One. 2011;6(8):e23407. Erratum in: PLoS One. 2011;6(11). PMID: 21858104.

 

Lee KJ, Jeong HG. Protective effects of kahweol and cafestol against hydrogen peroxide-induced oxidative stress and DNA damage. Toxicol Lett. 2007 Sep 10;173(2):80-7. PMID: 17689207.

 

Cavin C, Mace K, Offord EA, et al. Protective effects of coffee diterpenes against aflatoxin B1-induced genotoxicity: mechanisms in rat and human cells. Food Chem Toxicol. 2001 Jun;39(6):549-56. PMID: 11346484.

" Not dangerous goods.

LKT K0030 Kahweol 500 mg 2007.2 Diterpene found in coffee beans. 6894-43-5 ≥97% 314.42 C20H26O3 CC12C=CC3=C(C1CCC45C2CCC(C4)C(C5)(CO)O)C=CO3 Blue Ice -20°C Ethanol 5 mg/mL, DMF 5 mg/mL, DMSO 3 mg/mL. "Chae JI, Jeon YJ, Shim JH. Anti-Proliferative Properties of Kahweol in Oral Squamous Cancer Through the Regulation Specificity Protein 1. Phytother Res. 2014 Sep 8. [Epub ahead of print]. PMID: 25196544.

 

Wu KC, McDonald PR, Liu J, et al. Screening of natural compounds as activators of the keap1-nrf2 pathway. Planta Med. 2014 Jan;80(1):97-104. PMID: 24310212.

 

Fumimoto R, Sakai E, Yamaguchi Y, et al. The coffee diterpene kahweol prevents osteoclastogenesis via impairment of NFATc1 expression and blocking of Erk phosphorylation. J Pharmacol Sci. 2012;118(4):479-86. PMID: 22447306.

 

Cárdenas C, Quesada AR, Medina MA. Anti-angiogenic and anti-inflammatory properties of kahweol, a coffee diterpene. PLoS One. 2011;6(8):e23407. Erratum in: PLoS One. 2011;6(11). PMID: 21858104.

 

Lee KJ, Jeong HG. Protective effects of kahweol and cafestol against hydrogen peroxide-induced oxidative stress and DNA damage. Toxicol Lett. 2007 Sep 10;173(2):80-7. PMID: 17689207.

 

Cavin C, Mace K, Offord EA, et al. Protective effects of coffee diterpenes against aflatoxin B1-induced genotoxicity: mechanisms in rat and human cells. Food Chem Toxicol. 2001 Jun;39(6):549-56. PMID: 11346484.

" Not dangerous goods.

LKT K0031 Kahweol Acetate 10 mg 167.3 Diterpene found in coffee beans. 81760-47-6 ≥98% 356.47 C22H28O4 CC(=O)OCC1(CC23CCC4C5=C(C=CC4(C2CCC1C3)C)OC=C5)O Blue Ice -20°C Ethyl acetate, acetone, DMSO "Chae JI, Jeon YJ, Shim JH. Anti-Proliferative Properties of Kahweol in Oral Squamous Cancer Through the Regulation Specificity Protein 1. Phytother Res. 2014 Sep 8. [Epub ahead of print]. PMID: 25196544.

 

Wu KC, McDonald PR, Liu J, et al. Screening of natural compounds as activators of the keap1-nrf2 pathway. Planta Med. 2014 Jan;80(1):97-104. PMID: 24310212.

 

Fumimoto R, Sakai E, Yamaguchi Y, et al. The coffee diterpene kahweol prevents osteoclastogenesis via impairment of NFATc1 expression and blocking of Erk phosphorylation. J Pharmacol Sci. 2012;118(4):479-86. PMID: 22447306.

 

Cárdenas C, Quesada AR, Medina MA. Anti-angiogenic and anti-inflammatory properties of kahweol, a coffee diterpene. PLoS One. 2011;6(8):e23407. Erratum in: PLoS One. 2011;6(11). PMID: 21858104.

 

Lee KJ, Jeong HG. Protective effects of kahweol and cafestol against hydrogen peroxide-induced oxidative stress and DNA damage. Toxicol Lett. 2007 Sep 10;173(2):80-7. PMID: 17689207.

 

Cavin C, Mace K, Offord EA, et al. Protective effects of coffee diterpenes against aflatoxin B1-induced genotoxicity: mechanisms in rat and human cells. Food Chem Toxicol. 2001 Jun;39(6):549-56. PMID: 11346484.

" Not dangerous goods.

LKT K0031 Kahweol Acetate 25 mg 273.3 Diterpene found in coffee beans. 81760-47-6 ≥98% 356.47 C22H28O4 CC(=O)OCC1(CC23CCC4C5=C(C=CC4(C2CCC1C3)C)OC=C5)O Blue Ice -20°C Ethyl acetate, acetone, DMSO "Chae JI, Jeon YJ, Shim JH. Anti-Proliferative Properties of Kahweol in Oral Squamous Cancer Through the Regulation Specificity Protein 1. Phytother Res. 2014 Sep 8. [Epub ahead of print]. PMID: 25196544.

 

Wu KC, McDonald PR, Liu J, et al. Screening of natural compounds as activators of the keap1-nrf2 pathway. Planta Med. 2014 Jan;80(1):97-104. PMID: 24310212.

 

Fumimoto R, Sakai E, Yamaguchi Y, et al. The coffee diterpene kahweol prevents osteoclastogenesis via impairment of NFATc1 expression and blocking of Erk phosphorylation. J Pharmacol Sci. 2012;118(4):479-86. PMID: 22447306.

 

Cárdenas C, Quesada AR, Medina MA. Anti-angiogenic and anti-inflammatory properties of kahweol, a coffee diterpene. PLoS One. 2011;6(8):e23407. Erratum in: PLoS One. 2011;6(11). PMID: 21858104.

 

Lee KJ, Jeong HG. Protective effects of kahweol and cafestol against hydrogen peroxide-induced oxidative stress and DNA damage. Toxicol Lett. 2007 Sep 10;173(2):80-7. PMID: 17689207.

 

Cavin C, Mace K, Offord EA, et al. Protective effects of coffee diterpenes against aflatoxin B1-induced genotoxicity: mechanisms in rat and human cells. Food Chem Toxicol. 2001 Jun;39(6):549-56. PMID: 11346484.

" Not dangerous goods.

LKT K0031 Kahweol Acetate 100 mg 602.5 Diterpene found in coffee beans. 81760-47-6 ≥98% 356.47 C22H28O4 CC(=O)OCC1(CC23CCC4C5=C(C=CC4(C2CCC1C3)C)OC=C5)O Blue Ice -20°C Ethyl acetate, acetone, DMSO "Chae JI, Jeon YJ, Shim JH. Anti-Proliferative Properties of Kahweol in Oral Squamous Cancer Through the Regulation Specificity Protein 1. Phytother Res. 2014 Sep 8. [Epub ahead of print]. PMID: 25196544.

 

Wu KC, McDonald PR, Liu J, et al. Screening of natural compounds as activators of the keap1-nrf2 pathway. Planta Med. 2014 Jan;80(1):97-104. PMID: 24310212.

 

Fumimoto R, Sakai E, Yamaguchi Y, et al. The coffee diterpene kahweol prevents osteoclastogenesis via impairment of NFATc1 expression and blocking of Erk phosphorylation. J Pharmacol Sci. 2012;118(4):479-86. PMID: 22447306.

 

Cárdenas C, Quesada AR, Medina MA. Anti-angiogenic and anti-inflammatory properties of kahweol, a coffee diterpene. PLoS One. 2011;6(8):e23407. Erratum in: PLoS One. 2011;6(11). PMID: 21858104.

 

Lee KJ, Jeong HG. Protective effects of kahweol and cafestol against hydrogen peroxide-induced oxidative stress and DNA damage. Toxicol Lett. 2007 Sep 10;173(2):80-7. PMID: 17689207.

 

Cavin C, Mace K, Offord EA, et al. Protective effects of coffee diterpenes against aflatoxin B1-induced genotoxicity: mechanisms in rat and human cells. Food Chem Toxicol. 2001 Jun;39(6):549-56. PMID: 11346484.

" Not dangerous goods.

LKT K0031 Kahweol Acetate 500 mg 2067.6 Diterpene found in coffee beans. 81760-47-6 ≥98% 356.47 C22H28O4 CC(=O)OCC1(CC23CCC4C5=C(C=CC4(C2CCC1C3)C)OC=C5)O Blue Ice -20°C Ethyl acetate, acetone, DMSO "Chae JI, Jeon YJ, Shim JH. Anti-Proliferative Properties of Kahweol in Oral Squamous Cancer Through the Regulation Specificity Protein 1. Phytother Res. 2014 Sep 8. [Epub ahead of print]. PMID: 25196544.

 

Wu KC, McDonald PR, Liu J, et al. Screening of natural compounds as activators of the keap1-nrf2 pathway. Planta Med. 2014 Jan;80(1):97-104. PMID: 24310212.

 

Fumimoto R, Sakai E, Yamaguchi Y, et al. The coffee diterpene kahweol prevents osteoclastogenesis via impairment of NFATc1 expression and blocking of Erk phosphorylation. J Pharmacol Sci. 2012;118(4):479-86. PMID: 22447306.

 

Cárdenas C, Quesada AR, Medina MA. Anti-angiogenic and anti-inflammatory properties of kahweol, a coffee diterpene. PLoS One. 2011;6(8):e23407. Erratum in: PLoS One. 2011;6(11). PMID: 21858104.

 

Lee KJ, Jeong HG. Protective effects of kahweol and cafestol against hydrogen peroxide-induced oxidative stress and DNA damage. Toxicol Lett. 2007 Sep 10;173(2):80-7. PMID: 17689207.

 

Cavin C, Mace K, Offord EA, et al. Protective effects of coffee diterpenes against aflatoxin B1-induced genotoxicity: mechanisms in rat and human cells. Food Chem Toxicol. 2001 Jun;39(6):549-56. PMID: 11346484.

" Not dangerous goods.

LKT K0032 Kahweol Palmitate 10 mg 160.9 Diterpene found in coffee beans. 81760-45-4 ≥97% 552.42 C36H56O4 CCCCCCCCCCCCCCCC(=O)OCC1(CC23CCC4C5=C(C=CC4(C2CCC1C3)C)OC=C5)O -20°C for up to 3 months; -80°C for up to 6 months. Blue Ice -20°C "Chae JI, Jeon YJ, Shim JH. Anti-Proliferative Properties of Kahweol in Oral Squamous Cancer Through the Regulation Specificity Protein 1. Phytother Res. 2014 Sep 8. [Epub ahead of print]. PMID: 25196544.

 

Wu KC, McDonald PR, Liu J, et al. Screening of natural compounds as activators of the keap1-nrf2 pathway. Planta Med. 2014 Jan;80(1):97-104. PMID: 24310212.

 

Fumimoto R, Sakai E, Yamaguchi Y, et al. The coffee diterpene kahweol prevents osteoclastogenesis via impairment of NFATc1 expression and blocking of Erk phosphorylation. J Pharmacol Sci. 2012;118(4):479-86. PMID: 22447306.

 

Cárdenas C, Quesada AR, Medina MA. Anti-angiogenic and anti-inflammatory properties of kahweol, a coffee diterpene. PLoS One. 2011;6(8):e23407. Erratum in: PLoS One. 2011;6(11). PMID: 21858104.

 

Lee KJ, Jeong HG. Protective effects of kahweol and cafestol against hydrogen peroxide-induced oxidative stress and DNA damage. Toxicol Lett. 2007 Sep 10;173(2):80-7. PMID: 17689207.

 

Cavin C, Mace K, Offord EA, et al. Protective effects of coffee diterpenes against aflatoxin B1-induced genotoxicity: mechanisms in rat and human cells. Food Chem Toxicol. 2001 Jun;39(6):549-56. PMID: 11346484.

" Not dangerous goods.

LKT K0032 Kahweol Palmitate 25 mg 273.3 Diterpene found in coffee beans. 81760-45-4 ≥97% 552.42 C36H56O4 CCCCCCCCCCCCCCCC(=O)OCC1(CC23CCC4C5=C(C=CC4(C2CCC1C3)C)OC=C5)O -20°C for up to 3 months; -80°C for up to 6 months. Blue Ice -20°C "Chae JI, Jeon YJ, Shim JH. Anti-Proliferative Properties of Kahweol in Oral Squamous Cancer Through the Regulation Specificity Protein 1. Phytother Res. 2014 Sep 8. [Epub ahead of print]. PMID: 25196544.

 

Wu KC, McDonald PR, Liu J, et al. Screening of natural compounds as activators of the keap1-nrf2 pathway. Planta Med. 2014 Jan;80(1):97-104. PMID: 24310212.

 

Fumimoto R, Sakai E, Yamaguchi Y, et al. The coffee diterpene kahweol prevents osteoclastogenesis via impairment of NFATc1 expression and blocking of Erk phosphorylation. J Pharmacol Sci. 2012;118(4):479-86. PMID: 22447306.

 

Cárdenas C, Quesada AR, Medina MA. Anti-angiogenic and anti-inflammatory properties of kahweol, a coffee diterpene. PLoS One. 2011;6(8):e23407. Erratum in: PLoS One. 2011;6(11). PMID: 21858104.

 

Lee KJ, Jeong HG. Protective effects of kahweol and cafestol against hydrogen peroxide-induced oxidative stress and DNA damage. Toxicol Lett. 2007 Sep 10;173(2):80-7. PMID: 17689207.

 

Cavin C, Mace K, Offord EA, et al. Protective effects of coffee diterpenes against aflatoxin B1-induced genotoxicity: mechanisms in rat and human cells. Food Chem Toxicol. 2001 Jun;39(6):549-56. PMID: 11346484.

" Not dangerous goods.

LKT K0032 Kahweol Palmitate 100 mg 602.5 Diterpene found in coffee beans. 81760-45-4 ≥97% 552.42 C36H56O4 CCCCCCCCCCCCCCCC(=O)OCC1(CC23CCC4C5=C(C=CC4(C2CCC1C3)C)OC=C5)O -20°C for up to 3 months; -80°C for up to 6 months. Blue Ice -20°C "Chae JI, Jeon YJ, Shim JH. Anti-Proliferative Properties of Kahweol in Oral Squamous Cancer Through the Regulation Specificity Protein 1. Phytother Res. 2014 Sep 8. [Epub ahead of print]. PMID: 25196544.

 

Wu KC, McDonald PR, Liu J, et al. Screening of natural compounds as activators of the keap1-nrf2 pathway. Planta Med. 2014 Jan;80(1):97-104. PMID: 24310212.

 

Fumimoto R, Sakai E, Yamaguchi Y, et al. The coffee diterpene kahweol prevents osteoclastogenesis via impairment of NFATc1 expression and blocking of Erk phosphorylation. J Pharmacol Sci. 2012;118(4):479-86. PMID: 22447306.

 

Cárdenas C, Quesada AR, Medina MA. Anti-angiogenic and anti-inflammatory properties of kahweol, a coffee diterpene. PLoS One. 2011;6(8):e23407. Erratum in: PLoS One. 2011;6(11). PMID: 21858104.

 

Lee KJ, Jeong HG. Protective effects of kahweol and cafestol against hydrogen peroxide-induced oxidative stress and DNA damage. Toxicol Lett. 2007 Sep 10;173(2):80-7. PMID: 17689207.

 

Cavin C, Mace K, Offord EA, et al. Protective effects of coffee diterpenes against aflatoxin B1-induced genotoxicity: mechanisms in rat and human cells. Food Chem Toxicol. 2001 Jun;39(6):549-56. PMID: 11346484.

" Not dangerous goods.

LKT K0032 Kahweol Palmitate 500 mg 2067.6 Diterpene found in coffee beans. 81760-45-4 ≥97% 552.42 C36H56O4 CCCCCCCCCCCCCCCC(=O)OCC1(CC23CCC4C5=C(C=CC4(C2CCC1C3)C)OC=C5)O -20°C for up to 3 months; -80°C for up to 6 months. Blue Ice -20°C "Chae JI, Jeon YJ, Shim JH. Anti-Proliferative Properties of Kahweol in Oral Squamous Cancer Through the Regulation Specificity Protein 1. Phytother Res. 2014 Sep 8. [Epub ahead of print]. PMID: 25196544.

 

Wu KC, McDonald PR, Liu J, et al. Screening of natural compounds as activators of the keap1-nrf2 pathway. Planta Med. 2014 Jan;80(1):97-104. PMID: 24310212.

 

Fumimoto R, Sakai E, Yamaguchi Y, et al. The coffee diterpene kahweol prevents osteoclastogenesis via impairment of NFATc1 expression and blocking of Erk phosphorylation. J Pharmacol Sci. 2012;118(4):479-86. PMID: 22447306.

 

Cárdenas C, Quesada AR, Medina MA. Anti-angiogenic and anti-inflammatory properties of kahweol, a coffee diterpene. PLoS One. 2011;6(8):e23407. Erratum in: PLoS One. 2011;6(11). PMID: 21858104.

 

Lee KJ, Jeong HG. Protective effects of kahweol and cafestol against hydrogen peroxide-induced oxidative stress and DNA damage. Toxicol Lett. 2007 Sep 10;173(2):80-7. PMID: 17689207.

 

Cavin C, Mace K, Offord EA, et al. Protective effects of coffee diterpenes against aflatoxin B1-induced genotoxicity: mechanisms in rat and human cells. Food Chem Toxicol. 2001 Jun;39(6):549-56. PMID: 11346484.

" Not dangerous goods.

LKT K0034 Kahweol Eicosanate 10 mg 208.8 Diterpene found in coffee beans. 108214-32-0 ≥98% 608.93 C40H64O4 Blue Ice -20°C "Chae JI, Jeon YJ, Shim JH. Anti-Proliferative Properties of Kahweol in Oral Squamous Cancer Through the Regulation Specificity Protein 1. Phytother Res. 2014 Sep 8. [Epub ahead of print]. PMID: 25196544.

 

Wu KC, McDonald PR, Liu J, et al. Screening of natural compounds as activators of the keap1-nrf2 pathway. Planta Med. 2014 Jan;80(1):97-104. PMID: 24310212.

 

Fumimoto R, Sakai E, Yamaguchi Y, et al. The coffee diterpene kahweol prevents osteoclastogenesis via impairment of NFATc1 expression and blocking of Erk phosphorylation. J Pharmacol Sci. 2012;118(4):479-86. PMID: 22447306.

 

Cárdenas C, Quesada AR, Medina MA. Anti-angiogenic and anti-inflammatory properties of kahweol, a coffee diterpene. PLoS One. 2011;6(8):e23407. Erratum in: PLoS One. 2011;6(11). PMID: 21858104.

 

Lee KJ, Jeong HG. Protective effects of kahweol and cafestol against hydrogen peroxide-induced oxidative stress and DNA damage. Toxicol Lett. 2007 Sep 10;173(2):80-7. PMID: 17689207.

 

Cavin C, Mace K, Offord EA, et al. Protective effects of coffee diterpenes against aflatoxin B1-induced genotoxicity: mechanisms in rat and human cells. Food Chem Toxicol. 2001 Jun;39(6):549-56. PMID: 11346484.

" Not dangerous goods.

LKT K0034 Kahweol Eicosanate 25 mg 344.7 Diterpene found in coffee beans. 108214-32-0 ≥98% 608.93 C40H64O4 Blue Ice -20°C "Chae JI, Jeon YJ, Shim JH. Anti-Proliferative Properties of Kahweol in Oral Squamous Cancer Through the Regulation Specificity Protein 1. Phytother Res. 2014 Sep 8. [Epub ahead of print]. PMID: 25196544.

 

Wu KC, McDonald PR, Liu J, et al. Screening of natural compounds as activators of the keap1-nrf2 pathway. Planta Med. 2014 Jan;80(1):97-104. PMID: 24310212.

 

Fumimoto R, Sakai E, Yamaguchi Y, et al. The coffee diterpene kahweol prevents osteoclastogenesis via impairment of NFATc1 expression and blocking of Erk phosphorylation. J Pharmacol Sci. 2012;118(4):479-86. PMID: 22447306.

 

Cárdenas C, Quesada AR, Medina MA. Anti-angiogenic and anti-inflammatory properties of kahweol, a coffee diterpene. PLoS One. 2011;6(8):e23407. Erratum in: PLoS One. 2011;6(11). PMID: 21858104.

 

Lee KJ, Jeong HG. Protective effects of kahweol and cafestol against hydrogen peroxide-induced oxidative stress and DNA damage. Toxicol Lett. 2007 Sep 10;173(2):80-7. PMID: 17689207.

 

Cavin C, Mace K, Offord EA, et al. Protective effects of coffee diterpenes against aflatoxin B1-induced genotoxicity: mechanisms in rat and human cells. Food Chem Toxicol. 2001 Jun;39(6):549-56. PMID: 11346484.

" Not dangerous goods.

LKT K0034 Kahweol Eicosanate 100 mg 873.2 Diterpene found in coffee beans. 108214-32-0 ≥98% 608.93 C40H64O4 Blue Ice -20°C "Chae JI, Jeon YJ, Shim JH. Anti-Proliferative Properties of Kahweol in Oral Squamous Cancer Through the Regulation Specificity Protein 1. Phytother Res. 2014 Sep 8. [Epub ahead of print]. PMID: 25196544.

 

Wu KC, McDonald PR, Liu J, et al. Screening of natural compounds as activators of the keap1-nrf2 pathway. Planta Med. 2014 Jan;80(1):97-104. PMID: 24310212.

 

Fumimoto R, Sakai E, Yamaguchi Y, et al. The coffee diterpene kahweol prevents osteoclastogenesis via impairment of NFATc1 expression and blocking of Erk phosphorylation. J Pharmacol Sci. 2012;118(4):479-86. PMID: 22447306.

 

Cárdenas C, Quesada AR, Medina MA. Anti-angiogenic and anti-inflammatory properties of kahweol, a coffee diterpene. PLoS One. 2011;6(8):e23407. Erratum in: PLoS One. 2011;6(11). PMID: 21858104.

 

Lee KJ, Jeong HG. Protective effects of kahweol and cafestol against hydrogen peroxide-induced oxidative stress and DNA damage. Toxicol Lett. 2007 Sep 10;173(2):80-7. PMID: 17689207.

 

Cavin C, Mace K, Offord EA, et al. Protective effects of coffee diterpenes against aflatoxin B1-induced genotoxicity: mechanisms in rat and human cells. Food Chem Toxicol. 2001 Jun;39(6):549-56. PMID: 11346484.

" Not dangerous goods.

LKT K0036 Kahweol Linoleate 10 mg 203.7 Diterpene found in coffee beans. 108214-29-5 ≥98% 576.85 C38H56O4 Blue Ice -20°C "Chae JI, Jeon YJ, Shim JH. Anti-Proliferative Properties of Kahweol in Oral Squamous Cancer Through the Regulation Specificity Protein 1. Phytother Res. 2014 Sep 8. [Epub ahead of print]. PMID: 25196544.

 

Wu KC, McDonald PR, Liu J, et al. Screening of natural compounds as activators of the keap1-nrf2 pathway. Planta Med. 2014 Jan;80(1):97-104. PMID: 24310212.

 

Fumimoto R, Sakai E, Yamaguchi Y, et al. The coffee diterpene kahweol prevents osteoclastogenesis via impairment of NFATc1 expression and blocking of Erk phosphorylation. J Pharmacol Sci. 2012;118(4):479-86. PMID: 22447306.

 

Cárdenas C, Quesada AR, Medina MA. Anti-angiogenic and anti-inflammatory properties of kahweol, a coffee diterpene. PLoS One. 2011;6(8):e23407. Erratum in: PLoS One. 2011;6(11). PMID: 21858104.

 

Lee KJ, Jeong HG. Protective effects of kahweol and cafestol against hydrogen peroxide-induced oxidative stress and DNA damage. Toxicol Lett. 2007 Sep 10;173(2):80-7. PMID: 17689207.

 

Cavin C, Mace K, Offord EA, et al. Protective effects of coffee diterpenes against aflatoxin B1-induced genotoxicity: mechanisms in rat and human cells. Food Chem Toxicol. 2001 Jun;39(6):549-56. PMID: 11346484.

" Not dangerous goods.

LKT K0036 Kahweol Linoleate 25 mg 336 Diterpene found in coffee beans. 108214-29-5 ≥98% 576.85 C38H56O4 Blue Ice -20°C "Chae JI, Jeon YJ, Shim JH. Anti-Proliferative Properties of Kahweol in Oral Squamous Cancer Through the Regulation Specificity Protein 1. Phytother Res. 2014 Sep 8. [Epub ahead of print]. PMID: 25196544.

 

Wu KC, McDonald PR, Liu J, et al. Screening of natural compounds as activators of the keap1-nrf2 pathway. Planta Med. 2014 Jan;80(1):97-104. PMID: 24310212.

 

Fumimoto R, Sakai E, Yamaguchi Y, et al. The coffee diterpene kahweol prevents osteoclastogenesis via impairment of NFATc1 expression and blocking of Erk phosphorylation. J Pharmacol Sci. 2012;118(4):479-86. PMID: 22447306.

 

Cárdenas C, Quesada AR, Medina MA. Anti-angiogenic and anti-inflammatory properties of kahweol, a coffee diterpene. PLoS One. 2011;6(8):e23407. Erratum in: PLoS One. 2011;6(11). PMID: 21858104.

 

Lee KJ, Jeong HG. Protective effects of kahweol and cafestol against hydrogen peroxide-induced oxidative stress and DNA damage. Toxicol Lett. 2007 Sep 10;173(2):80-7. PMID: 17689207.

 

Cavin C, Mace K, Offord EA, et al. Protective effects of coffee diterpenes against aflatoxin B1-induced genotoxicity: mechanisms in rat and human cells. Food Chem Toxicol. 2001 Jun;39(6):549-56. PMID: 11346484.

" Not dangerous goods.

LKT K0036 Kahweol Linoleate 100 mg 857.1 Diterpene found in coffee beans. 108214-29-5 ≥98% 576.85 C38H56O4 Blue Ice -20°C "Chae JI, Jeon YJ, Shim JH. Anti-Proliferative Properties of Kahweol in Oral Squamous Cancer Through the Regulation Specificity Protein 1. Phytother Res. 2014 Sep 8. [Epub ahead of print]. PMID: 25196544.

 

Wu KC, McDonald PR, Liu J, et al. Screening of natural compounds as activators of the keap1-nrf2 pathway. Planta Med. 2014 Jan;80(1):97-104. PMID: 24310212.

 

Fumimoto R, Sakai E, Yamaguchi Y, et al. The coffee diterpene kahweol prevents osteoclastogenesis via impairment of NFATc1 expression and blocking of Erk phosphorylation. J Pharmacol Sci. 2012;118(4):479-86. PMID: 22447306.

 

Cárdenas C, Quesada AR, Medina MA. Anti-angiogenic and anti-inflammatory properties of kahweol, a coffee diterpene. PLoS One. 2011;6(8):e23407. Erratum in: PLoS One. 2011;6(11). PMID: 21858104.

 

Lee KJ, Jeong HG. Protective effects of kahweol and cafestol against hydrogen peroxide-induced oxidative stress and DNA damage. Toxicol Lett. 2007 Sep 10;173(2):80-7. PMID: 17689207.

 

Cavin C, Mace K, Offord EA, et al. Protective effects of coffee diterpenes against aflatoxin B1-induced genotoxicity: mechanisms in rat and human cells. Food Chem Toxicol. 2001 Jun;39(6):549-56. PMID: 11346484.

" Not dangerous goods.

LKT K0038 Kahweol Oleate 10 mg 211.7 Diterpene found in coffee beans. 108214-30-8 ≥98% 578.86 C38H58O4 Blue Ice -20°C "Chae JI, Jeon YJ, Shim JH. Anti-Proliferative Properties of Kahweol in Oral Squamous Cancer Through the Regulation Specificity Protein 1. Phytother Res. 2014 Sep 8. [Epub ahead of print]. PMID: 25196544.

 

Wu KC, McDonald PR, Liu J, et al. Screening of natural compounds as activators of the keap1-nrf2 pathway. Planta Med. 2014 Jan;80(1):97-104. PMID: 24310212.

 

Fumimoto R, Sakai E, Yamaguchi Y, et al. The coffee diterpene kahweol prevents osteoclastogenesis via impairment of NFATc1 expression and blocking of Erk phosphorylation. J Pharmacol Sci. 2012;118(4):479-86. PMID: 22447306.

 

Cárdenas C, Quesada AR, Medina MA. Anti-angiogenic and anti-inflammatory properties of kahweol, a coffee diterpene. PLoS One. 2011;6(8):e23407. Erratum in: PLoS One. 2011;6(11). PMID: 21858104.

 

Lee KJ, Jeong HG. Protective effects of kahweol and cafestol against hydrogen peroxide-induced oxidative stress and DNA damage. Toxicol Lett. 2007 Sep 10;173(2):80-7. PMID: 17689207.

 

Cavin C, Mace K, Offord EA, et al. Protective effects of coffee diterpenes against aflatoxin B1-induced genotoxicity: mechanisms in rat and human cells. Food Chem Toxicol. 2001 Jun;39(6):549-56. PMID: 11346484.

" Not dangerous goods.

LKT K0038 Kahweol Oleate 25 mg 359.9 Diterpene found in coffee beans. 108214-30-8 ≥98% 578.86 C38H58O4 Blue Ice -20°C "Chae JI, Jeon YJ, Shim JH. Anti-Proliferative Properties of Kahweol in Oral Squamous Cancer Through the Regulation Specificity Protein 1. Phytother Res. 2014 Sep 8. [Epub ahead of print]. PMID: 25196544.

 

Wu KC, McDonald PR, Liu J, et al. Screening of natural compounds as activators of the keap1-nrf2 pathway. Planta Med. 2014 Jan;80(1):97-104. PMID: 24310212.

 

Fumimoto R, Sakai E, Yamaguchi Y, et al. The coffee diterpene kahweol prevents osteoclastogenesis via impairment of NFATc1 expression and blocking of Erk phosphorylation. J Pharmacol Sci. 2012;118(4):479-86. PMID: 22447306.

 

Cárdenas C, Quesada AR, Medina MA. Anti-angiogenic and anti-inflammatory properties of kahweol, a coffee diterpene. PLoS One. 2011;6(8):e23407. Erratum in: PLoS One. 2011;6(11). PMID: 21858104.

 

Lee KJ, Jeong HG. Protective effects of kahweol and cafestol against hydrogen peroxide-induced oxidative stress and DNA damage. Toxicol Lett. 2007 Sep 10;173(2):80-7. PMID: 17689207.

 

Cavin C, Mace K, Offord EA, et al. Protective effects of coffee diterpenes against aflatoxin B1-induced genotoxicity: mechanisms in rat and human cells. Food Chem Toxicol. 2001 Jun;39(6):549-56. PMID: 11346484.

" Not dangerous goods.

LKT K0038 Kahweol Oleate 100 mg 888.9 Diterpene found in coffee beans. 108214-30-8 ≥98% 578.86 C38H58O4 Blue Ice -20°C "Chae JI, Jeon YJ, Shim JH. Anti-Proliferative Properties of Kahweol in Oral Squamous Cancer Through the Regulation Specificity Protein 1. Phytother Res. 2014 Sep 8. [Epub ahead of print]. PMID: 25196544.

 

Wu KC, McDonald PR, Liu J, et al. Screening of natural compounds as activators of the keap1-nrf2 pathway. Planta Med. 2014 Jan;80(1):97-104. PMID: 24310212.

 

Fumimoto R, Sakai E, Yamaguchi Y, et al. The coffee diterpene kahweol prevents osteoclastogenesis via impairment of NFATc1 expression and blocking of Erk phosphorylation. J Pharmacol Sci. 2012;118(4):479-86. PMID: 22447306.

 

Cárdenas C, Quesada AR, Medina MA. Anti-angiogenic and anti-inflammatory properties of kahweol, a coffee diterpene. PLoS One. 2011;6(8):e23407. Erratum in: PLoS One. 2011;6(11). PMID: 21858104.

 

Lee KJ, Jeong HG. Protective effects of kahweol and cafestol against hydrogen peroxide-induced oxidative stress and DNA damage. Toxicol Lett. 2007 Sep 10;173(2):80-7. PMID: 17689207.

 

Cavin C, Mace K, Offord EA, et al. Protective effects of coffee diterpenes against aflatoxin B1-induced genotoxicity: mechanisms in rat and human cells. Food Chem Toxicol. 2001 Jun;39(6):549-56. PMID: 11346484.

" Not dangerous goods.

LKT K0040 Kahweol Stearate 10 mg 196.8 Diterpene found in coffee beans. 108214-31-9 ≥98% 580.88 C38H60O4 Blue Ice -20°C "Chae JI, Jeon YJ, Shim JH. Anti-Proliferative Properties of Kahweol in Oral Squamous Cancer Through the Regulation Specificity Protein 1. Phytother Res. 2014 Sep 8. [Epub ahead of print]. PMID: 25196544.

 

Wu KC, McDonald PR, Liu J, et al. Screening of natural compounds as activators of the keap1-nrf2 pathway. Planta Med. 2014 Jan;80(1):97-104. PMID: 24310212.

 

Fumimoto R, Sakai E, Yamaguchi Y, et al. The coffee diterpene kahweol prevents osteoclastogenesis via impairment of NFATc1 expression and blocking of Erk phosphorylation. J Pharmacol Sci. 2012;118(4):479-86. PMID: 22447306.

 

Cárdenas C, Quesada AR, Medina MA. Anti-angiogenic and anti-inflammatory properties of kahweol, a coffee diterpene. PLoS One. 2011;6(8):e23407. Erratum in: PLoS One. 2011;6(11). PMID: 21858104.

 

Lee KJ, Jeong HG. Protective effects of kahweol and cafestol against hydrogen peroxide-induced oxidative stress and DNA damage. Toxicol Lett. 2007 Sep 10;173(2):80-7. PMID: 17689207.

 

Cavin C, Mace K, Offord EA, et al. Protective effects of coffee diterpenes against aflatoxin B1-induced genotoxicity: mechanisms in rat and human cells. Food Chem Toxicol. 2001 Jun;39(6):549-56. PMID: 11346484.

" Not dangerous goods.

LKT K0040 Kahweol Stearate 25 mg 318.2 Diterpene found in coffee beans. 108214-31-9 ≥98% 580.88 C38H60O4 Blue Ice -20°C "Chae JI, Jeon YJ, Shim JH. Anti-Proliferative Properties of Kahweol in Oral Squamous Cancer Through the Regulation Specificity Protein 1. Phytother Res. 2014 Sep 8. [Epub ahead of print]. PMID: 25196544.

 

Wu KC, McDonald PR, Liu J, et al. Screening of natural compounds as activators of the keap1-nrf2 pathway. Planta Med. 2014 Jan;80(1):97-104. PMID: 24310212.

 

Fumimoto R, Sakai E, Yamaguchi Y, et al. The coffee diterpene kahweol prevents osteoclastogenesis via impairment of NFATc1 expression and blocking of Erk phosphorylation. J Pharmacol Sci. 2012;118(4):479-86. PMID: 22447306.

 

Cárdenas C, Quesada AR, Medina MA. Anti-angiogenic and anti-inflammatory properties of kahweol, a coffee diterpene. PLoS One. 2011;6(8):e23407. Erratum in: PLoS One. 2011;6(11). PMID: 21858104.

 

Lee KJ, Jeong HG. Protective effects of kahweol and cafestol against hydrogen peroxide-induced oxidative stress and DNA damage. Toxicol Lett. 2007 Sep 10;173(2):80-7. PMID: 17689207.

 

Cavin C, Mace K, Offord EA, et al. Protective effects of coffee diterpenes against aflatoxin B1-induced genotoxicity: mechanisms in rat and human cells. Food Chem Toxicol. 2001 Jun;39(6):549-56. PMID: 11346484.

" Not dangerous goods.

LKT K0040 Kahweol Stearate 100 mg 816.7 Diterpene found in coffee beans. 108214-31-9 ≥98% 580.88 C38H60O4 Blue Ice -20°C "Chae JI, Jeon YJ, Shim JH. Anti-Proliferative Properties of Kahweol in Oral Squamous Cancer Through the Regulation Specificity Protein 1. Phytother Res. 2014 Sep 8. [Epub ahead of print]. PMID: 25196544.

 

Wu KC, McDonald PR, Liu J, et al. Screening of natural compounds as activators of the keap1-nrf2 pathway. Planta Med. 2014 Jan;80(1):97-104. PMID: 24310212.

 

Fumimoto R, Sakai E, Yamaguchi Y, et al. The coffee diterpene kahweol prevents osteoclastogenesis via impairment of NFATc1 expression and blocking of Erk phosphorylation. J Pharmacol Sci. 2012;118(4):479-86. PMID: 22447306.

 

Cárdenas C, Quesada AR, Medina MA. Anti-angiogenic and anti-inflammatory properties of kahweol, a coffee diterpene. PLoS One. 2011;6(8):e23407. Erratum in: PLoS One. 2011;6(11). PMID: 21858104.

 

Lee KJ, Jeong HG. Protective effects of kahweol and cafestol against hydrogen peroxide-induced oxidative stress and DNA damage. Toxicol Lett. 2007 Sep 10;173(2):80-7. PMID: 17689207.

 

Cavin C, Mace K, Offord EA, et al. Protective effects of coffee diterpenes against aflatoxin B1-induced genotoxicity: mechanisms in rat and human cells. Food Chem Toxicol. 2001 Jun;39(6):549-56. PMID: 11346484.

" Not dangerous goods.

LKT K0053 Kanamycin A 1 g 35.3 Aminoglycoside; protein translation inhibitor, mammalian RNA splicing inhibitor. "D-Streptamine,O-3-amino-3-deoxy-alpha-D- glucopyranosyl-(1-6)-O-(6-amino-6-deoxy-alpha-D- glucopyranosyl-(1-4))-2-deoxy- 

" Kanamycin 59-01-8 ≥98% 484.5 C18H36N4O11 C1C(C(C(C(C1N)OC2C(C(C(C(O2)CN)O)O)O)O)OC3C(C(C(C(O3)CO)O)N)O)N Ambient Ambient Soluble in water (100mM) or alcohol. "Romanowska J, Reuter N, Trylska J. Comparing aminoglycoside binding sites in bacterial ribosomal RNA and aminoglycoside modifying enzymes. Proteins. 2013 Jan;81(1):63-80. PMID: 22907688.

 

Patwardhan A, Cowan JA. Influence of charge and structure on the coordination chemistry of copper aminoglycosides. Dalton Trans. 2011 Feb 28;40(8):1795-801. PMID: 21218243.

 

Aukema KG, Chohan KK, Plourde GL, et al. Small molecule inhibitors of yeast pre-mRNA splicing. ACS Chem Biol. 2009 Sep 18;4(9):759-68. PMID: 19634919." Not dangerous goods.

LKT K0053 Kanamycin A 5 g 101.9 Aminoglycoside; protein translation inhibitor, mammalian RNA splicing inhibitor. "D-Streptamine,O-3-amino-3-deoxy-alpha-D- glucopyranosyl-(1-6)-O-(6-amino-6-deoxy-alpha-D- glucopyranosyl-(1-4))-2-deoxy- 

" Kanamycin 59-01-8 ≥98% 484.5 C18H36N4O11 C1C(C(C(C(C1N)OC2C(C(C(C(O2)CN)O)O)O)O)OC3C(C(C(C(O3)CO)O)N)O)N Ambient Ambient Soluble in water (100mM) or alcohol. "Romanowska J, Reuter N, Trylska J. Comparing aminoglycoside binding sites in bacterial ribosomal RNA and aminoglycoside modifying enzymes. Proteins. 2013 Jan;81(1):63-80. PMID: 22907688.

 

Patwardhan A, Cowan JA. Influence of charge and structure on the coordination chemistry of copper aminoglycosides. Dalton Trans. 2011 Feb 28;40(8):1795-801. PMID: 21218243.

 

Aukema KG, Chohan KK, Plourde GL, et al. Small molecule inhibitors of yeast pre-mRNA splicing. ACS Chem Biol. 2009 Sep 18;4(9):759-68. PMID: 19634919." Not dangerous goods.

LKT K0053 Kanamycin A 25 g 251.5 Aminoglycoside; protein translation inhibitor, mammalian RNA splicing inhibitor. "D-Streptamine,O-3-amino-3-deoxy-alpha-D- glucopyranosyl-(1-6)-O-(6-amino-6-deoxy-alpha-D- glucopyranosyl-(1-4))-2-deoxy- 

" Kanamycin 59-01-8 ≥98% 484.5 C18H36N4O11 C1C(C(C(C(C1N)OC2C(C(C(C(O2)CN)O)O)O)O)OC3C(C(C(C(O3)CO)O)N)O)N Ambient Ambient Soluble in water (100mM) or alcohol. "Romanowska J, Reuter N, Trylska J. Comparing aminoglycoside binding sites in bacterial ribosomal RNA and aminoglycoside modifying enzymes. Proteins. 2013 Jan;81(1):63-80. PMID: 22907688.

 

Patwardhan A, Cowan JA. Influence of charge and structure on the coordination chemistry of copper aminoglycosides. Dalton Trans. 2011 Feb 28;40(8):1795-801. PMID: 21218243.

 

Aukema KG, Chohan KK, Plourde GL, et al. Small molecule inhibitors of yeast pre-mRNA splicing. ACS Chem Biol. 2009 Sep 18;4(9):759-68. PMID: 19634919." Not dangerous goods.

LKT K0054 Kanamycin B 100 mg 35.3 Aminoglycoside; protein translation inhibitor, mammalian RNA splicing inhibitor. "O-3-amino-3-deoxy-alpha-D-glucopyranosyl-(1-

4)-O-(2,6-diamino-2,6-dideoxy-alpha-D-gluco- pyranosyl-(1-6))-2-deoxy-D-Streptamine" Bekanamycin; NK-1006; Nebramycin V. 4696-76-8 ≥98% 483.51 C18H37N5O10 C1C(C(C(C(C1N)OC2C(C(C(C(O2)CO)O)N)O)O)OC3C(C(C(C(O3)CN)O)O)N)N Ambient Ambient Soluble in water or formamide. Slightly soluble  in chloroform, isopropyl alcohol. "Patwardhan A, Cowan JA. Influence of charge and structure on the coordination chemistry of copper aminoglycosides. Dalton Trans. 2011 Feb 28;40(8):1795-801. PMID: 21218243.

 

Aukema KG, Chohan KK, Plourde GL, et al. Small molecule inhibitors of yeast pre-mRNA splicing. ACS Chem Biol. 2009 Sep 18;4(9):759-68. PMID: 19634919.

 

Morales MA, Castrillon JL, Hernandez DA. Effects of bekanamycin and dibekacin on the electrical activity of cardiac pacemaker cells. Arch Med Res. 1993 Winter;24(4):339-45. PMID: 8118157.

" Not dangerous goods.

LKT K0054 Kanamycin B 250 mg 88.3 Aminoglycoside; protein translation inhibitor, mammalian RNA splicing inhibitor. "O-3-amino-3-deoxy-alpha-D-glucopyranosyl-(1-

4)-O-(2,6-diamino-2,6-dideoxy-alpha-D-gluco- pyranosyl-(1-6))-2-deoxy-D-Streptamine" Bekanamycin; NK-1006; Nebramycin V. 4696-76-8 ≥98% 483.51 C18H37N5O10 C1C(C(C(C(C1N)OC2C(C(C(C(O2)CO)O)N)O)O)OC3C(C(C(C(O3)CN)O)O)N)N Ambient Ambient Soluble in water or formamide. Slightly soluble  in chloroform, isopropyl alcohol. "Patwardhan A, Cowan JA. Influence of charge and structure on the coordination chemistry of copper aminoglycosides. Dalton Trans. 2011 Feb 28;40(8):1795-801. PMID: 21218243.

 

Aukema KG, Chohan KK, Plourde GL, et al. Small molecule inhibitors of yeast pre-mRNA splicing. ACS Chem Biol. 2009 Sep 18;4(9):759-68. PMID: 19634919.

 

Morales MA, Castrillon JL, Hernandez DA. Effects of bekanamycin and dibekacin on the electrical activity of cardiac pacemaker cells. Arch Med Res. 1993 Winter;24(4):339-45. PMID: 8118157.

" Not dangerous goods.

LKT K0054 Kanamycin B 1 g 237.8 Aminoglycoside; protein translation inhibitor, mammalian RNA splicing inhibitor. "O-3-amino-3-deoxy-alpha-D-glucopyranosyl-(1-

4)-O-(2,6-diamino-2,6-dideoxy-alpha-D-gluco- pyranosyl-(1-6))-2-deoxy-D-Streptamine" Bekanamycin; NK-1006; Nebramycin V. 4696-76-8 ≥98% 483.51 C18H37N5O10 C1C(C(C(C(C1N)OC2C(C(C(C(O2)CO)O)N)O)O)OC3C(C(C(C(O3)CN)O)O)N)N Ambient Ambient Soluble in water or formamide. Slightly soluble  in chloroform, isopropyl alcohol. "Patwardhan A, Cowan JA. Influence of charge and structure on the coordination chemistry of copper aminoglycosides. Dalton Trans. 2011 Feb 28;40(8):1795-801. PMID: 21218243.

 

Aukema KG, Chohan KK, Plourde GL, et al. Small molecule inhibitors of yeast pre-mRNA splicing. ACS Chem Biol. 2009 Sep 18;4(9):759-68. PMID: 19634919.

 

Morales MA, Castrillon JL, Hernandez DA. Effects of bekanamycin and dibekacin on the electrical activity of cardiac pacemaker cells. Arch Med Res. 1993 Winter;24(4):339-45. PMID: 8118157.

" Not dangerous goods.

LKT K0088 Kawain 5 mg 186.6 Kavalactone originally found in Piper methysticum (kava plant); Voltage-gated Na+ and L-type Ca2+ channel blocker. (6R)-5,6-Dihydro-4-methoxy-6-[(1E)-2-phenyl- ethenyl]-2H-pyran-2-one Kavain; Gonosan 3155-48-4 ≥98% 230.26 C14H14O3 COC1=CC(=O)OC(C1)C=CC2=CC=CC=C2 Ambient -20°C Soluble in acetone, ether or methanol. Slightly soluble in hexane. Practically insoluble in water. "Tsutsui R, Shinomiya K, Takeda Y, et al. Hypnotic and sleep quality-enhancing properties of kavain in sleep-disturbed rats. J Pharmacol Sci. 2009 Nov;111(3):293-8. PMID: 19881224.

 

Wruck CJ, Götz ME, Herdegen T, et al. Kavalactones protect neural cells against amyloid beta peptide-induced neurotoxicity via extracellular signal-regulated kinase 1/2-dependent nuclear factor erythroid 2-related factor 2 activation. Mol Pharmacol. 2008 Jun;73(6):1785-95. PMID: 18334601.

 

Xuan TD, Elzaawely AA, Fukuta M, et al. Herbicidal and Fungicidal Activities of Lactones in Kava (Piper methysticum). J Agric Food Chem. 2006 Feb 8;54(3):720-5. PMID: 16448174.

 

Martin HB, McCallum M, Stofer WD, et al. Kavain attenuates vascular contractility through inhibition of calcium channels. Planta Med. 2002 Sep;68(9):784-9. PMID: 12357387.

 

Friese J, Gleitz J. Kavain, dihydrokavain, and dihydromethysticin non-competitively inhibit the specific binding of [3H]-batrachotoxinin-A 20-alpha-benzoate to receptor site 2 of voltage-gated Na+ channels. Planta Med. 1998 Jun;64(5):458-9. PMID: 9690349.

 

Magura EI, Kopanitsa MV, Gleitz J, et al. Kava extract ingredients, (+)-methysticin and (+/-)-kavain inhibit voltage-operated Na(+)-channels in rat CA1 hippocampal neurons. Neuroscience. 1997 Nov;81(2):345-51. Erratum in: Neuroscience 1998 May;84(1):323. PMID: 9300426.

 

Gleitz J, Beile A, Wilkens P, et al. Antithrombotic action of the kava pyrone (+)-kavain prepared from Piper methysticum on human platelets. Planta Med. 1997 Feb;63(1):27-30. PMID: 9063093.

 

Lindenberg D, Pitule-Schödel H. D,L-kavain in comparison with oxazepam in anxiety disorders. A double-blind study of clinical effectiveness. Fortschr Med. 1990 Jan 20;108(2):49-50, 53-4. PMID: 2179082.

" Xn Not dangerous goods.

LKT K0088 Kawain 10 mg 288.3 Kavalactone originally found in Piper methysticum (kava plant); Voltage-gated Na+ and L-type Ca2+ channel blocker. (6R)-5,6-Dihydro-4-methoxy-6-[(1E)-2-phenyl- ethenyl]-2H-pyran-2-one Kavain; Gonosan 3155-48-4 ≥98% 230.26 C14H14O3 COC1=CC(=O)OC(C1)C=CC2=CC=CC=C2 Ambient -20°C Soluble in acetone, ether or methanol. Slightly soluble in hexane. Practically insoluble in water. "Tsutsui R, Shinomiya K, Takeda Y, et al. Hypnotic and sleep quality-enhancing properties of kavain in sleep-disturbed rats. J Pharmacol Sci. 2009 Nov;111(3):293-8. PMID: 19881224.

 

Wruck CJ, Götz ME, Herdegen T, et al. Kavalactones protect neural cells against amyloid beta peptide-induced neurotoxicity via extracellular signal-regulated kinase 1/2-dependent nuclear factor erythroid 2-related factor 2 activation. Mol Pharmacol. 2008 Jun;73(6):1785-95. PMID: 18334601.

 

Xuan TD, Elzaawely AA, Fukuta M, et al. Herbicidal and Fungicidal Activities of Lactones in Kava (Piper methysticum). J Agric Food Chem. 2006 Feb 8;54(3):720-5. PMID: 16448174.

 

Martin HB, McCallum M, Stofer WD, et al. Kavain attenuates vascular contractility through inhibition of calcium channels. Planta Med. 2002 Sep;68(9):784-9. PMID: 12357387.

 

Friese J, Gleitz J. Kavain, dihydrokavain, and dihydromethysticin non-competitively inhibit the specific binding of [3H]-batrachotoxinin-A 20-alpha-benzoate to receptor site 2 of voltage-gated Na+ channels. Planta Med. 1998 Jun;64(5):458-9. PMID: 9690349.

 

Magura EI, Kopanitsa MV, Gleitz J, et al. Kava extract ingredients, (+)-methysticin and (+/-)-kavain inhibit voltage-operated Na(+)-channels in rat CA1 hippocampal neurons. Neuroscience. 1997 Nov;81(2):345-51. Erratum in: Neuroscience 1998 May;84(1):323. PMID: 9300426.

 

Gleitz J, Beile A, Wilkens P, et al. Antithrombotic action of the kava pyrone (+)-kavain prepared from Piper methysticum on human platelets. Planta Med. 1997 Feb;63(1):27-30. PMID: 9063093.

 

Lindenberg D, Pitule-Schödel H. D,L-kavain in comparison with oxazepam in anxiety disorders. A double-blind study of clinical effectiveness. Fortschr Med. 1990 Jan 20;108(2):49-50, 53-4. PMID: 2179082.

" Xn Not dangerous goods.

LKT K0117 Kaempferol 1 mg 33.9 Flavonol found in various plant sources. 3,5,7-Trihydroxy-2-(4-hydroxyphenyl)-4H-1-benzo- pyran-4-one Nimbecetin; Populnetin; Rhamnolutein; Robigenin; Swartziol; Trifolitin 520-18-3 ≥98% 286.24 C15H10O6 C1=CC(=CC=C1C2=C(C(=O)C3=C(C=C(C=C3O2)O)O)O)O Ambient -20°C Slightly soluble in water. Soluble in hot alcohol, ether or alkalies. "Tang XL, Liu JX, Dong W, et al. Protective Effect of Kaempferol on LPS plus ATP-Induced Inflammatory Response in Cardiac Fibroblasts. Inflammation. 2014 Sep 5. [Epub ahead of print]. PMID: 25189464.

 

Yang EJ, Kim GS, Jun M, et al. Kaempferol attenuates the glutamate-induced oxidative stress in mouse-derived hippocampal neuronal HT22 cells. Food Funct. 2014 Jul 25;5(7):1395-402. PMID: 24770605.

 

Dang Q, Song W, Xu D, et al. Kaempferol suppresses bladder cancer tumor growth by inhibiting cell proliferation and inducing apoptosis. Mol Carcinog. 2014 Apr 2. [Epub ahead of print]. PMID: 24700700.

 

Chen HJ, Lin CM, Lee CY, et al. Kaempferol suppresses cell metastasis via inhibition of the ERK-p38-JNK and AP-1 signaling pathways in U-2 OS human osteosarcoma cells. Oncol Rep. 2013 Aug;30(2):925-32. PMID: 23708932.

 

Park UH, Jeong JC, Jang JS, et al. Negative regulation of adipogenesis by kaempferol, a component of Rhizoma Polygonati falcatum in 3T3-L1 cells. Biol Pharm Bull. 2012;35(9):1525-33. PMID: 22975504.

 

Luo H, Rankin GO, Juliano N, et al. Kaempferol inhibits VEGF expression and in vitro angiogenesis through a novel ERK-NFκB-cMyc-p21 pathway. Food Chem. 2012 Jan 15;130(2):321-328. PMID: 21927533.

" T Not dangerous goods.

LKT K0117 Kaempferol 5 mg 47.6 Flavonol found in various plant sources. 3,5,7-Trihydroxy-2-(4-hydroxyphenyl)-4H-1-benzo- pyran-4-one Nimbecetin; Populnetin; Rhamnolutein; Robigenin; Swartziol; Trifolitin 520-18-3 ≥98% 286.24 C15H10O6 C1=CC(=CC=C1C2=C(C(=O)C3=C(C=C(C=C3O2)O)O)O)O Ambient -20°C Slightly soluble in water. Soluble in hot alcohol, ether or alkalies. "Tang XL, Liu JX, Dong W, et al. Protective Effect of Kaempferol on LPS plus ATP-Induced Inflammatory Response in Cardiac Fibroblasts. Inflammation. 2014 Sep 5. [Epub ahead of print]. PMID: 25189464.

 

Yang EJ, Kim GS, Jun M, et al. Kaempferol attenuates the glutamate-induced oxidative stress in mouse-derived hippocampal neuronal HT22 cells. Food Funct. 2014 Jul 25;5(7):1395-402. PMID: 24770605.

 

Dang Q, Song W, Xu D, et al. Kaempferol suppresses bladder cancer tumor growth by inhibiting cell proliferation and inducing apoptosis. Mol Carcinog. 2014 Apr 2. [Epub ahead of print]. PMID: 24700700.

 

Chen HJ, Lin CM, Lee CY, et al. Kaempferol suppresses cell metastasis via inhibition of the ERK-p38-JNK and AP-1 signaling pathways in U-2 OS human osteosarcoma cells. Oncol Rep. 2013 Aug;30(2):925-32. PMID: 23708932.

 

Park UH, Jeong JC, Jang JS, et al. Negative regulation of adipogenesis by kaempferol, a component of Rhizoma Polygonati falcatum in 3T3-L1 cells. Biol Pharm Bull. 2012;35(9):1525-33. PMID: 22975504.

 

Luo H, Rankin GO, Juliano N, et al. Kaempferol inhibits VEGF expression and in vitro angiogenesis through a novel ERK-NFκB-cMyc-p21 pathway. Food Chem. 2012 Jan 15;130(2):321-328. PMID: 21927533.

" T Not dangerous goods.

LKT K0117 Kaempferol 10 mg 54.4 Flavonol found in various plant sources. 3,5,7-Trihydroxy-2-(4-hydroxyphenyl)-4H-1-benzo- pyran-4-one Nimbecetin; Populnetin; Rhamnolutein; Robigenin; Swartziol; Trifolitin 520-18-3 ≥98% 286.24 C15H10O6 C1=CC(=CC=C1C2=C(C(=O)C3=C(C=C(C=C3O2)O)O)O)O Ambient -20°C Slightly soluble in water. Soluble in hot alcohol, ether or alkalies. "Tang XL, Liu JX, Dong W, et al. Protective Effect of Kaempferol on LPS plus ATP-Induced Inflammatory Response in Cardiac Fibroblasts. Inflammation. 2014 Sep 5. [Epub ahead of print]. PMID: 25189464.

 

Yang EJ, Kim GS, Jun M, et al. Kaempferol attenuates the glutamate-induced oxidative stress in mouse-derived hippocampal neuronal HT22 cells. Food Funct. 2014 Jul 25;5(7):1395-402. PMID: 24770605.

 

Dang Q, Song W, Xu D, et al. Kaempferol suppresses bladder cancer tumor growth by inhibiting cell proliferation and inducing apoptosis. Mol Carcinog. 2014 Apr 2. [Epub ahead of print]. PMID: 24700700.

 

Chen HJ, Lin CM, Lee CY, et al. Kaempferol suppresses cell metastasis via inhibition of the ERK-p38-JNK and AP-1 signaling pathways in U-2 OS human osteosarcoma cells. Oncol Rep. 2013 Aug;30(2):925-32. PMID: 23708932.

 

Park UH, Jeong JC, Jang JS, et al. Negative regulation of adipogenesis by kaempferol, a component of Rhizoma Polygonati falcatum in 3T3-L1 cells. Biol Pharm Bull. 2012;35(9):1525-33. PMID: 22975504.

 

Luo H, Rankin GO, Juliano N, et al. Kaempferol inhibits VEGF expression and in vitro angiogenesis through a novel ERK-NFκB-cMyc-p21 pathway. Food Chem. 2012 Jan 15;130(2):321-328. PMID: 21927533.

" T Not dangerous goods.

LKT K0133 Kainic Acid 10 mg 283.1 Excitatory amino acid found in seaweed; AMPA and kainate agonist. [2S-(2α,3β,4β)]-2-Carboxy-4-(1-methylethenyl)-3- pyrrolidineacetic acid Digenin; Helminal 487-79-6 ≥98% 213.23 C10H15NO4 CC(=C)C1CNC(C1CC(=O)O)C(=O)O Ambient Ambient Soluble in water. Insoluble in ethanol. "Fritsch B, Reis J, Gasior M, et al. Role of GluK1 kainate receptors in seizures, epileptic discharges, and epileptogenesis. J Neurosci. 2014 Apr 23;34(17):5765-75. PMID: 24760837.

 

Ben-Ari Y. Kainate and Temporal Lobe Epilepsies: 3 decades of progress. In: Noebels JL, Avoli M, Rogawski MA, et al. editors. Jasper's Basic Mechanisms of the Epilepsies [Internet]. 4th edition. Bethesda (MD): National Center for Biotechnology Information (US); 2012. PMID: 22787646.

" Xn Not dangerous goods.

LKT K0133 Kainic Acid 25 mg 682.3 Excitatory amino acid found in seaweed; AMPA and kainate agonist. [2S-(2α,3β,4β)]-2-Carboxy-4-(1-methylethenyl)-3- pyrrolidineacetic acid Digenin; Helminal 487-79-6 ≥98% 213.23 C10H15NO4 CC(=C)C1CNC(C1CC(=O)O)C(=O)O Ambient Ambient Soluble in water. Insoluble in ethanol. "Fritsch B, Reis J, Gasior M, et al. Role of GluK1 kainate receptors in seizures, epileptic discharges, and epileptogenesis. J Neurosci. 2014 Apr 23;34(17):5765-75. PMID: 24760837.

 

Ben-Ari Y. Kainate and Temporal Lobe Epilepsies: 3 decades of progress. In: Noebels JL, Avoli M, Rogawski MA, et al. editors. Jasper's Basic Mechanisms of the Epilepsies [Internet]. 4th edition. Bethesda (MD): National Center for Biotechnology Information (US); 2012. PMID: 22787646.

" Xn Not dangerous goods.

LKT K0133 Kainic Acid 100 mg 2534.6 Excitatory amino acid found in seaweed; AMPA and kainate agonist. [2S-(2α,3β,4β)]-2-Carboxy-4-(1-methylethenyl)-3- pyrrolidineacetic acid Digenin; Helminal 487-79-6 ≥98% 213.23 C10H15NO4 CC(=C)C1CNC(C1CC(=O)O)C(=O)O Ambient Ambient Soluble in water. Insoluble in ethanol. "Fritsch B, Reis J, Gasior M, et al. Role of GluK1 kainate receptors in seizures, epileptic discharges, and epileptogenesis. J Neurosci. 2014 Apr 23;34(17):5765-75. PMID: 24760837.

 

Ben-Ari Y. Kainate and Temporal Lobe Epilepsies: 3 decades of progress. In: Noebels JL, Avoli M, Rogawski MA, et al. editors. Jasper's Basic Mechanisms of the Epilepsies [Internet]. 4th edition. Bethesda (MD): National Center for Biotechnology Information (US); 2012. PMID: 22787646.

" Xn Not dangerous goods.

LKT K0144 Kallikrein Inhibitor 1 mg 60 Peptide; serine protease inhibitor. KKI 5 97145-43-2 ≥95% 773.9 C35H55N11O9 CC(C)C(C(=O)NC(CCC(=O)N)C(=O)N)NC(=O)C(CO)NC(=O)C(CCCN=C(N)N)NC(=O)C(CC1=CC=CC=C1)NC(=O)C2CCCN2C(=O)C Ambient -20°C "Bilgin M, Burgazli KM, Rafiq A, et al. Effect of bauhinia bauhinioides kallikrein inhibitor on endothelial proliferation and intracellular calcium concentration. Eur Rev Med Pharmacol Sci. 2014 Jan;18(1):46-51. PMID: 24452941.

 

Nakahata AM, Mayer B, Neth P, et al. Blocking the proliferation of human tumor cell lines by peptidase inhibitors from Bauhinia seeds. Planta Med. 2013 Mar;79(3-4):227-35. PMID: 23345168.

 

Levy JH, O'Donnell PS. The therapeutic potential of a kallikrein inhibitor for treating hereditary angioedema. Expert Opin Investig Drugs. 2006 Sep;15(9):1077-90. PMID: 16916274.

" Not dangerous goods.

LKT K0144 Kallikrein Inhibitor 2 mg 101.9 Peptide; serine protease inhibitor. KKI 5 97145-43-2 ≥95% 773.9 C35H55N11O9 CC(C)C(C(=O)NC(CCC(=O)N)C(=O)N)NC(=O)C(CO)NC(=O)C(CCCN=C(N)N)NC(=O)C(CC1=CC=CC=C1)NC(=O)C2CCCN2C(=O)C Ambient -20°C "Bilgin M, Burgazli KM, Rafiq A, et al. Effect of bauhinia bauhinioides kallikrein inhibitor on endothelial proliferation and intracellular calcium concentration. Eur Rev Med Pharmacol Sci. 2014 Jan;18(1):46-51. PMID: 24452941.

 

Nakahata AM, Mayer B, Neth P, et al. Blocking the proliferation of human tumor cell lines by peptidase inhibitors from Bauhinia seeds. Planta Med. 2013 Mar;79(3-4):227-35. PMID: 23345168.

 

Levy JH, O'Donnell PS. The therapeutic potential of a kallikrein inhibitor for treating hereditary angioedema. Expert Opin Investig Drugs. 2006 Sep;15(9):1077-90. PMID: 16916274.

" Not dangerous goods.

LKT K0144 Kallikrein Inhibitor 5 mg 180 Peptide; serine protease inhibitor. KKI 5 97145-43-2 ≥95% 773.9 C35H55N11O9 CC(C)C(C(=O)NC(CCC(=O)N)C(=O)N)NC(=O)C(CO)NC(=O)C(CCCN=C(N)N)NC(=O)C(CC1=CC=CC=C1)NC(=O)C2CCCN2C(=O)C Ambient -20°C "Bilgin M, Burgazli KM, Rafiq A, et al. Effect of bauhinia bauhinioides kallikrein inhibitor on endothelial proliferation and intracellular calcium concentration. Eur Rev Med Pharmacol Sci. 2014 Jan;18(1):46-51. PMID: 24452941.

 

Nakahata AM, Mayer B, Neth P, et al. Blocking the proliferation of human tumor cell lines by peptidase inhibitors from Bauhinia seeds. Planta Med. 2013 Mar;79(3-4):227-35. PMID: 23345168.

 

Levy JH, O'Donnell PS. The therapeutic potential of a kallikrein inhibitor for treating hereditary angioedema. Expert Opin Investig Drugs. 2006 Sep;15(9):1077-90. PMID: 16916274.

" Not dangerous goods.

LKT K0172 Kassinin 1 mg 60 Tachykinin neuropeptide found in amphibians; NK2 agonist. L-alpha-Aspartyl-L-valyl-L-prolyl-L-lysyl-L-seryl-L-alpha-aspartyl-L-glutaminyl-L-phenylalanyl-L-valylglycyl-L-leucyl-L-Methioninamide "

" 63968-82-1 ≥95% 1334.6 C59H95N15O18S CC(C)CC(C(=O)NC(CCSC)C(=O)N)NC(=O)CNC(=O)C(C(C)C)NC(=O)C(CC1=CC=CC=C1)NC(=O)C(CCC(=O)N)NC(=O)C(CC(=O)O)NC(=O)C(CO)NC(=O)C(CCCCN)NC(=O)C2CCCN2C(=O)C(C(C)C)NC(=O)C(CC(=O)O)N Ambient -20°C "Lippe C, Bellantuono V, Ardizzone C, et al. Eledoisin and Kassinin, but not Enterokassinin, stimulate ion transport in frog skin. Peptides. 2004 Nov;25(11):1971-5. PMID: 15501529.

 

Bolle P, Severini C, Falconieri-Erspamer G, et al. Effects of natural tachykinins on porcine lower urinary tract smooth muscle. J Auton Pharmacol. 2000 Jun;20(3):157-61. PMID: 11193004.

 

Improta G, Broccardo M. Tachykinins: effects on gastric secretion and emptying in rats. Pharmacol Res. 1990 Sep-Oct;22(5):605-10. PMID: 2177557.

" Not dangerous goods.

LKT K0172 Kassinin 2 mg 101.9 Tachykinin neuropeptide found in amphibians; NK2 agonist. L-alpha-Aspartyl-L-valyl-L-prolyl-L-lysyl-L-seryl-L-alpha-aspartyl-L-glutaminyl-L-phenylalanyl-L-valylglycyl-L-leucyl-L-Methioninamide "

" 63968-82-1 ≥95% 1334.6 C59H95N15O18S CC(C)CC(C(=O)NC(CCSC)C(=O)N)NC(=O)CNC(=O)C(C(C)C)NC(=O)C(CC1=CC=CC=C1)NC(=O)C(CCC(=O)N)NC(=O)C(CC(=O)O)NC(=O)C(CO)NC(=O)C(CCCCN)NC(=O)C2CCCN2C(=O)C(C(C)C)NC(=O)C(CC(=O)O)N Ambient -20°C "Lippe C, Bellantuono V, Ardizzone C, et al. Eledoisin and Kassinin, but not Enterokassinin, stimulate ion transport in frog skin. Peptides. 2004 Nov;25(11):1971-5. PMID: 15501529.

 

Bolle P, Severini C, Falconieri-Erspamer G, et al. Effects of natural tachykinins on porcine lower urinary tract smooth muscle. J Auton Pharmacol. 2000 Jun;20(3):157-61. PMID: 11193004.

 

Improta G, Broccardo M. Tachykinins: effects on gastric secretion and emptying in rats. Pharmacol Res. 1990 Sep-Oct;22(5):605-10. PMID: 2177557.

" Not dangerous goods.

LKT K0172 Kassinin 5 mg 180 Tachykinin neuropeptide found in amphibians; NK2 agonist. L-alpha-Aspartyl-L-valyl-L-prolyl-L-lysyl-L-seryl-L-alpha-aspartyl-L-glutaminyl-L-phenylalanyl-L-valylglycyl-L-leucyl-L-Methioninamide "

" 63968-82-1 ≥95% 1334.6 C59H95N15O18S CC(C)CC(C(=O)NC(CCSC)C(=O)N)NC(=O)CNC(=O)C(C(C)C)NC(=O)C(CC1=CC=CC=C1)NC(=O)C(CCC(=O)N)NC(=O)C(CC(=O)O)NC(=O)C(CO)NC(=O)C(CCCCN)NC(=O)C2CCCN2C(=O)C(C(C)C)NC(=O)C(CC(=O)O)N Ambient -20°C "Lippe C, Bellantuono V, Ardizzone C, et al. Eledoisin and Kassinin, but not Enterokassinin, stimulate ion transport in frog skin. Peptides. 2004 Nov;25(11):1971-5. PMID: 15501529.

 

Bolle P, Severini C, Falconieri-Erspamer G, et al. Effects of natural tachykinins on porcine lower urinary tract smooth muscle. J Auton Pharmacol. 2000 Jun;20(3):157-61. PMID: 11193004.

 

Improta G, Broccardo M. Tachykinins: effects on gastric secretion and emptying in rats. Pharmacol Res. 1990 Sep-Oct;22(5):605-10. PMID: 2177557.

" Not dangerous goods.

LKT K0276 Katacalcin 0.5 mg 156 Peptide found in crustaceans; PKA activator. CCAP, CCP I, Calcitonin carboxyl-terminal flanking peptide 85916-47-8 ≥95% 2436.64 C97H154N34O36S2 CC(C)CC(C(=O)NC(CCC(=O)O)C(=O)NC(CCCNC(=N)N)C(=O)NC(CC(=O)O)C(=O)NC(CC1=CN=CN1)C(=O)NC(CCCNC(=N)N)C(=O)N2CCCC2C(=O)NC(CC3=CN=CN3)C(=O)NC(C(C)C)C(=O)NC(C(=O)NC(CCSC)C(=O)N4CCCC4C(=O)NC(CCC(=O)N)C(=O)NC(CC(=O)N)C(=O)NC(C)C(=O)NC(CC(=O)N)C(=O)O)OC)NC(=O)C(CC(=O)O)NC(=O)C(CO)NC(=O)C(CO)NC(=O)C(CCSC)NC(=O)C(CC(=O)O)N Ambient -20°C "Kaneider NC, Egger P, Wiedermann FJ, et al. Involvement of cyclic adenosine monophosphate-dependent protein kinase A and pertussis toxin-sensitive G proteins in the migratory response of human CD14+ mononuclear cells to katacalcin. J Bone Miner Res. 2002 Oct;17(10):1872-82. PMID: 12369791.

 

Angelucci F, Gruber SH, Mathé AA. A pilot study of rat brain regional distribution of calcitonin, katacalcin and calcitonin gene-related peptide before and after antipsychotic treatment. Neuropeptides. 2001 Oct-Dec;35(5-6):285-91. PMID: 12030813.

 

Blind E, Raue F, Klaiber T, et al. Evaluation of sensitive PDN-21 (katacalcin) determination as tumor marker in medullary thyroid carcinoma. J Endocrinol Invest. 1992 Feb;15(2):93-8. PMID: 1569295.

"

LKT K0276 Katacalcin 1 mg 264.1 Peptide found in crustaceans; PKA activator. CCAP, CCP I, Calcitonin carboxyl-terminal flanking peptide 85916-47-8 ≥95% 2436.64 C97H154N34O36S2 CC(C)CC(C(=O)NC(CCC(=O)O)C(=O)NC(CCCNC(=N)N)C(=O)NC(CC(=O)O)C(=O)NC(CC1=CN=CN1)C(=O)NC(CCCNC(=N)N)C(=O)N2CCCC2C(=O)NC(CC3=CN=CN3)C(=O)NC(C(C)C)C(=O)NC(C(=O)NC(CCSC)C(=O)N4CCCC4C(=O)NC(CCC(=O)N)C(=O)NC(CC(=O)N)C(=O)NC(C)C(=O)NC(CC(=O)N)C(=O)O)OC)NC(=O)C(CC(=O)O)NC(=O)C(CO)NC(=O)C(CO)NC(=O)C(CCSC)NC(=O)C(CC(=O)O)N Ambient -20°C "Kaneider NC, Egger P, Wiedermann FJ, et al. Involvement of cyclic adenosine monophosphate-dependent protein kinase A and pertussis toxin-sensitive G proteins in the migratory response of human CD14+ mononuclear cells to katacalcin. J Bone Miner Res. 2002 Oct;17(10):1872-82. PMID: 12369791.

 

Angelucci F, Gruber SH, Mathé AA. A pilot study of rat brain regional distribution of calcitonin, katacalcin and calcitonin gene-related peptide before and after antipsychotic treatment. Neuropeptides. 2001 Oct-Dec;35(5-6):285-91. PMID: 12030813.

 

Blind E, Raue F, Klaiber T, et al. Evaluation of sensitive PDN-21 (katacalcin) determination as tumor marker in medullary thyroid carcinoma. J Endocrinol Invest. 1992 Feb;15(2):93-8. PMID: 1569295.

"

LKT K0276 Katacalcin 2.5 mg 468.2 Peptide found in crustaceans; PKA activator. CCAP, CCP I, Calcitonin carboxyl-terminal flanking peptide 85916-47-8 ≥95% 2436.64 C97H154N34O36S2 CC(C)CC(C(=O)NC(CCC(=O)O)C(=O)NC(CCCNC(=N)N)C(=O)NC(CC(=O)O)C(=O)NC(CC1=CN=CN1)C(=O)NC(CCCNC(=N)N)C(=O)N2CCCC2C(=O)NC(CC3=CN=CN3)C(=O)NC(C(C)C)C(=O)NC(C(=O)NC(CCSC)C(=O)N4CCCC4C(=O)NC(CCC(=O)N)C(=O)NC(CC(=O)N)C(=O)NC(C)C(=O)NC(CC(=O)N)C(=O)O)OC)NC(=O)C(CC(=O)O)NC(=O)C(CO)NC(=O)C(CO)NC(=O)C(CCSC)NC(=O)C(CC(=O)O)N Ambient -20°C "Kaneider NC, Egger P, Wiedermann FJ, et al. Involvement of cyclic adenosine monophosphate-dependent protein kinase A and pertussis toxin-sensitive G proteins in the migratory response of human CD14+ mononuclear cells to katacalcin. J Bone Miner Res. 2002 Oct;17(10):1872-82. PMID: 12369791.

 

Angelucci F, Gruber SH, Mathé AA. A pilot study of rat brain regional distribution of calcitonin, katacalcin and calcitonin gene-related peptide before and after antipsychotic treatment. Neuropeptides. 2001 Oct-Dec;35(5-6):285-91. PMID: 12030813.

 

Blind E, Raue F, Klaiber T, et al. Evaluation of sensitive PDN-21 (katacalcin) determination as tumor marker in medullary thyroid carcinoma. J Endocrinol Invest. 1992 Feb;15(2):93-8. PMID: 1569295.

"

LKT K0282 Kavalactones Mixture 1 ml 652.3 Mixture of kavalactones found in Piper methysticum (kava plant). ≥98% Ambient -20°C "Kormann EC, Amaral Pde A, David M, et al. Kavain analogues as potential analgesic agents. Pharmacol Rep. 2012;64(6):1419-26. PMID: 23406752.

 

Tsutsui R, Shinomiya K, Takeda Y, et al. Hypnotic and sleep quality-enhancing properties of kavain in sleep-disturbed rats. J Pharmacol Sci. 2009 Nov;111(3):293-8. PMID: 19881224.

 

Wruck CJ, Götz ME, Herdegen T, et al. Kavalactones protect neural cells against amyloid beta peptide-induced neurotoxicity via extracellular signal-regulated kinase 1/2-dependent nuclear factor erythroid 2-related factor 2 activation. Mol Pharmacol. 2008 Jun;73(6):1785-95. PMID: 18334601.

 

Pittler MH, Ernst E. Kava extract for treating anxiety. Cochrane Database Syst Rev. 2003;(1):CD003383. PMID: 12535473.

 

Grunze H, Langosch J, Schirrmacher K, et al. Kava pyrones exert effects on neuronal transmission and transmembraneous cation currents similar to established mood stabilizers--a review. Prog Neuropsychopharmacol Biol Psychiatry. 2001 Nov;25(8):1555-70. PMID: 11642654.

 

Schmidt N, Ferger B. Neuroprotective effects of (+/-)-kavain in the MPTP mouse model of Parkinson's disease. Synapse. 2001 Apr;40(1):47-54. PMID: 11170221.

"

LKT K1650 Kemptide 1 mg 60 PKA substrate. 65189-71-1 ≥95% 771.92 C32H61N13O9 CC(C)CC(C(=O)NC(CCCN=C(N)N)C(=O)NC(CCCN=C(N)N)C(=O)NC(C)C(=O)NC(CO)C(=O)NC(CC(C)C)C(=O)NCC(=O)O)N Ambient -20°C "Montenegro M, Garcia-Viloca M, González-Lafont A, et al. Comparative study of the prereactive protein kinase A Michaelis complex with kemptide substrate. J Comput Aided Mol Des. 2007 Oct-Nov;21(10-11):603-15. PMID: 18008170.

 

Benyo DF, Zeleznik AJ. Cyclic adenosine monophosphate signaling in the primate corpus luteum: maintenance of protein kinase A activity throughout the luteal phase of the menstrual cycle. Endocrinology. 1997 Aug;138(8):3452-8. PMID: 9231800.

 

Whitehouse S, Feramisco JR, Casnellie JE, et al. Studies on the kinetic mechanism of the catalytic subunit of the cAMP-dependent protein kinase. J Biol Chem. 1983 Mar 25;258(6):3693-701. PMID: 6833226.

" Not dangerous goods.

LKT K1650 Kemptide 2 mg 101.9 PKA substrate. 65189-71-1 ≥95% 771.92 C32H61N13O9 CC(C)CC(C(=O)NC(CCCN=C(N)N)C(=O)NC(CCCN=C(N)N)C(=O)NC(C)C(=O)NC(CO)C(=O)NC(CC(C)C)C(=O)NCC(=O)O)N Ambient -20°C "Montenegro M, Garcia-Viloca M, González-Lafont A, et al. Comparative study of the prereactive protein kinase A Michaelis complex with kemptide substrate. J Comput Aided Mol Des. 2007 Oct-Nov;21(10-11):603-15. PMID: 18008170.

 

Benyo DF, Zeleznik AJ. Cyclic adenosine monophosphate signaling in the primate corpus luteum: maintenance of protein kinase A activity throughout the luteal phase of the menstrual cycle. Endocrinology. 1997 Aug;138(8):3452-8. PMID: 9231800.

 

Whitehouse S, Feramisco JR, Casnellie JE, et al. Studies on the kinetic mechanism of the catalytic subunit of the cAMP-dependent protein kinase. J Biol Chem. 1983 Mar 25;258(6):3693-701. PMID: 6833226.

" Not dangerous goods.

LKT K1650 Kemptide 5 mg 180 PKA substrate. 65189-71-1 ≥95% 771.92 C32H61N13O9 CC(C)CC(C(=O)NC(CCCN=C(N)N)C(=O)NC(CCCN=C(N)N)C(=O)NC(C)C(=O)NC(CO)C(=O)NC(CC(C)C)C(=O)NCC(=O)O)N Ambient -20°C "Montenegro M, Garcia-Viloca M, González-Lafont A, et al. Comparative study of the prereactive protein kinase A Michaelis complex with kemptide substrate. J Comput Aided Mol Des. 2007 Oct-Nov;21(10-11):603-15. PMID: 18008170.

 

Benyo DF, Zeleznik AJ. Cyclic adenosine monophosphate signaling in the primate corpus luteum: maintenance of protein kinase A activity throughout the luteal phase of the menstrual cycle. Endocrinology. 1997 Aug;138(8):3452-8. PMID: 9231800.

 

Whitehouse S, Feramisco JR, Casnellie JE, et al. Studies on the kinetic mechanism of the catalytic subunit of the cAMP-dependent protein kinase. J Biol Chem. 1983 Mar 25;258(6):3693-701. PMID: 6833226.

" Not dangerous goods.

LKT K1655 Kenpaullone 1 mg 111.7 GSK-3β, HGK, and CDK inhibitor. 9-Bromo-7,12-dihydroindolo-[3,2-d][1]benzazepin-6(5H)-one 142273-20-9 ≥95% 327.18 C16H11BrN2O C1C2=C(C3=CC=CC=C3NC1=O)NC4=C2C=C(C=C4)Br Ambient 4°C Soluble in DMSO. Insoluble in water and ethanol. "Zhang Y, Welzig CM, Picard KL, et al. Glycogen synthase kinase-3β inhibition ameliorates cardiac parasympathetic dysfunction in type 1 diabetic akita mice. Diabetes. 2014 Jun;63(6):2097-113. PMID: 24458356.

 

Yoshida H, Kotani H, Kondo T, et al. CDK inhibitors suppress Th17 and promote iTreg differentiation, and ameliorate experimental autoimmune encephalomyelitis in mice. Biochem Biophys Res Commun. 2013 Jun 7;435(3):378-84. PMID: 23665028.

 

Yang YM, Gupta SK, Kim KJ, et al. A small molecule screen in stem-cell-derived motor neurons identifies a kinase inhibitor as a candidate therapeutic for ALS. Cell Stem Cell. 2013 Jun 6;12(6):713-26. PMID: 23602540.

 

Petit-Paitel A, Brau F, Cazareth J, et al. Involvment of cytosolic and mitochondrial GSK-3beta in mitochondrial dysfunction and neuronal cell death of MPTP/MPP-treated neurons. PLoS One. 2009;4(5):e5491. PMID: 19430525.

" Xi Not dangerous goods.

LKT K1655 Kenpaullone 5 mg 412.5 GSK-3β, HGK, and CDK inhibitor. 9-Bromo-7,12-dihydroindolo-[3,2-d][1]benzazepin-6(5H)-one 142273-20-9 ≥95% 327.18 C16H11BrN2O C1C2=C(C3=CC=CC=C3NC1=O)NC4=C2C=C(C=C4)Br Ambient 4°C Soluble in DMSO. Insoluble in water and ethanol. "Zhang Y, Welzig CM, Picard KL, et al. Glycogen synthase kinase-3β inhibition ameliorates cardiac parasympathetic dysfunction in type 1 diabetic akita mice. Diabetes. 2014 Jun;63(6):2097-113. PMID: 24458356.

 

Yoshida H, Kotani H, Kondo T, et al. CDK inhibitors suppress Th17 and promote iTreg differentiation, and ameliorate experimental autoimmune encephalomyelitis in mice. Biochem Biophys Res Commun. 2013 Jun 7;435(3):378-84. PMID: 23665028.

 

Yang YM, Gupta SK, Kim KJ, et al. A small molecule screen in stem-cell-derived motor neurons identifies a kinase inhibitor as a candidate therapeutic for ALS. Cell Stem Cell. 2013 Jun 6;12(6):713-26. PMID: 23602540.

 

Petit-Paitel A, Brau F, Cazareth J, et al. Involvment of cytosolic and mitochondrial GSK-3beta in mitochondrial dysfunction and neuronal cell death of MPTP/MPP-treated neurons. PLoS One. 2009;4(5):e5491. PMID: 19430525.

" Xi Not dangerous goods.

LKT K1674 Ketolide Resistance Peptide MRFFV 1 mg 60 Peptide, prevents ketolide antibiotic-ribosome binding. ≥98% 698.9 C34H50N8O6S Ambient -20°C "Verdier L, Gharbi-Benarous J, Bertho G, et al. Antibiotic resistance peptides: interaction of peptides conferring macrolide and ketolide resistance with Staphylococcus aureus ribosomes: conformation of bound peptides as determined by transferred NOE experiments. Biochemistry. 2002 Apr 2;41(13):4218-29. PMID: 11914067.

 

Tripathi S, Kloss PS, Mankin AS. Ketolide resistance conferred by short peptides. J Biol Chem. 1998 Aug 7;273(32):20073-7. PMID: 9685347.

"

LKT K1674 Ketolide Resistance Peptide MRFFV 5 mg 225 Peptide, prevents ketolide antibiotic-ribosome binding. ≥98% 698.9 C34H50N8O6S Ambient -20°C "Verdier L, Gharbi-Benarous J, Bertho G, et al. Antibiotic resistance peptides: interaction of peptides conferring macrolide and ketolide resistance with Staphylococcus aureus ribosomes: conformation of bound peptides as determined by transferred NOE experiments. Biochemistry. 2002 Apr 2;41(13):4218-29. PMID: 11914067.

 

Tripathi S, Kloss PS, Mankin AS. Ketolide resistance conferred by short peptides. J Biol Chem. 1998 Aug 7;273(32):20073-7. PMID: 9685347.

"

LKT K1677 Ketoprofen 5 g 48.8 NSAID; COX-1/2 and lactate dehydrogenase inhibitor. 3-Benzoyl-a-methylbenzeneacetic acid Ketofen; Ketopron 22071-15-4 ≥98% 254.28 C16H14O3 CC(C1=CC=CC(=C1)C(=O)C2=CC=CC=C2)C(=O)O Ambient Ambient Soluble in ethanol, acetone or DMSO.  Slightly soluble in water. "Razi MT, Javed I, Choudry MZ, et al. Effect of ketoprofen on lactic dehydrogenase from human platelets. Adv Clin Exp Med. 2014 May-Jun;23(3):377-80. PMID: 24979508.

 

Brogliato AR, Antunes CA, Carvalho RS, et al. Ketoprofen impairs immunosuppression induced by severe sepsis and reveals an important role for prostaglandin E2. Shock. 2012 Dec;38(6):620-9. PMID: 23143054.

 

Kantor TG. Ketoprofen: a review of its pharmacologic and clinical properties. Pharmacotherapy. 1986 May-Jun;6(3):93-103. PMID: 3526298.

" Xi, T "UN number: 2811     Class: 6.1     Packing Group: III

Proper shipping name: Toxic solids, organic, n.o.s. (Ketoprofen)

Marine pollutant: No"

LKT K1677 Ketoprofen 25 g 183 NSAID; COX-1/2 and lactate dehydrogenase inhibitor. 3-Benzoyl-a-methylbenzeneacetic acid Ketofen; Ketopron 22071-15-4 ≥98% 254.28 C16H14O3 CC(C1=CC=CC(=C1)C(=O)C2=CC=CC=C2)C(=O)O Ambient Ambient Soluble in ethanol, acetone or DMSO.  Slightly soluble in water. "Razi MT, Javed I, Choudry MZ, et al. Effect of ketoprofen on lactic dehydrogenase from human platelets. Adv Clin Exp Med. 2014 May-Jun;23(3):377-80. PMID: 24979508.

 

Brogliato AR, Antunes CA, Carvalho RS, et al. Ketoprofen impairs immunosuppression induced by severe sepsis and reveals an important role for prostaglandin E2. Shock. 2012 Dec;38(6):620-9. PMID: 23143054.

 

Kantor TG. Ketoprofen: a review of its pharmacologic and clinical properties. Pharmacotherapy. 1986 May-Jun;6(3):93-103. PMID: 3526298.

" Xi, T "UN number: 2811     Class: 6.1     Packing Group: III

Proper shipping name: Toxic solids, organic, n.o.s. (Ketoprofen)

Marine pollutant: No"

LKT K1677 Ketoprofen 100 g 425.1 NSAID; COX-1/2 and lactate dehydrogenase inhibitor. 3-Benzoyl-a-methylbenzeneacetic acid Ketofen; Ketopron 22071-15-4 ≥98% 254.28 C16H14O3 CC(C1=CC=CC(=C1)C(=O)C2=CC=CC=C2)C(=O)O Ambient Ambient Soluble in ethanol, acetone or DMSO.  Slightly soluble in water. "Razi MT, Javed I, Choudry MZ, et al. Effect of ketoprofen on lactic dehydrogenase from human platelets. Adv Clin Exp Med. 2014 May-Jun;23(3):377-80. PMID: 24979508.

 

Brogliato AR, Antunes CA, Carvalho RS, et al. Ketoprofen impairs immunosuppression induced by severe sepsis and reveals an important role for prostaglandin E2. Shock. 2012 Dec;38(6):620-9. PMID: 23143054.

 

Kantor TG. Ketoprofen: a review of its pharmacologic and clinical properties. Pharmacotherapy. 1986 May-Jun;6(3):93-103. PMID: 3526298.

" Xi, T "UN number: 2811     Class: 6.1     Packing Group: III

Proper shipping name: Toxic solids, organic, n.o.s. (Ketoprofen)

Marine pollutant: No"

LKT K1678 Ketanserin 25 mg 75 5-HT2A antagonist, potential α1-adrenergic antagonist. 3-[2-[4-(4-Fluorobenzoyl)-1-piperidinyl]ethyl]-2,4[1H,3H]-quinazolinedione Perketan; Serefrex; Ketensin 74050-98-9 ≥97% 395.43 C22H22FN3O3 C1CN(CCC1C(=O)C2=CC=C(C=C2)F)CCN3C(=O)C4=CC=CC=C4NC3=O Ambient 4°C "Yu JG, Zhang EH, Liu AJ, et al. Ketanserin improves cardiac performance after myocardial infarction in spontaneously hypertensive rats partially through restoration of baroreflex function. Acta Pharmacol Sin. 2013 Dec;34(12):1508-14. PMID: 24241347.

 

Loyd DR, Chen PB, Hargreaves KM. Anti-hyperalgesic effects of anti-serotonergic compounds on serotonin- and capsaicin-evoked thermal hyperalgesia in the rat. Neuroscience. 2012 Feb 17;203:207-15. PMID: 22209919.

 

van Zwieten PA, Blauw GJ, van Brummelen P. Serotonergic receptors and drugs in hypertension. Pharmacol Toxicol. 1992 Jun;70(6 Pt 2):S17-22. PMID: 1354865.

 

Koss MC. Mechanism of ketanserin-induced sympatho-inhibition. Eur J Pharmacol. 1991 Mar 5;194(2-3):161-6. PMID: 1676374.

 

Kato S, Matsuda N, Matsumoto K, et al. Dual role of serotonin in the pathogenesis of indomethacin-induced small intestinal ulceration: pro-ulcerogenic action via 5-HT3 receptors and anti-ulcerogenic action via 5-HT4 receptors. Pharmacol Res. 2012 Sep;66(3):226-234. PMID: 22699012.

" "UN number: 2811     Class: 6.1     Packing Group: III

Proper shipping name: Toxic solid, organic, n.o.s. (Ketanserin)"

LKT K1678 Ketanserin 100 mg 187.4 5-HT2A antagonist, potential α1-adrenergic antagonist. 3-[2-[4-(4-Fluorobenzoyl)-1-piperidinyl]ethyl]-2,4[1H,3H]-quinazolinedione Perketan; Serefrex; Ketensin 74050-98-9 ≥97% 395.43 C22H22FN3O3 C1CN(CCC1C(=O)C2=CC=C(C=C2)F)CCN3C(=O)C4=CC=CC=C4NC3=O Ambient 4°C "Yu JG, Zhang EH, Liu AJ, et al. Ketanserin improves cardiac performance after myocardial infarction in spontaneously hypertensive rats partially through restoration of baroreflex function. Acta Pharmacol Sin. 2013 Dec;34(12):1508-14. PMID: 24241347.

 

Loyd DR, Chen PB, Hargreaves KM. Anti-hyperalgesic effects of anti-serotonergic compounds on serotonin- and capsaicin-evoked thermal hyperalgesia in the rat. Neuroscience. 2012 Feb 17;203:207-15. PMID: 22209919.

 

van Zwieten PA, Blauw GJ, van Brummelen P. Serotonergic receptors and drugs in hypertension. Pharmacol Toxicol. 1992 Jun;70(6 Pt 2):S17-22. PMID: 1354865.

 

Koss MC. Mechanism of ketanserin-induced sympatho-inhibition. Eur J Pharmacol. 1991 Mar 5;194(2-3):161-6. PMID: 1676374.

 

Kato S, Matsuda N, Matsumoto K, et al. Dual role of serotonin in the pathogenesis of indomethacin-induced small intestinal ulceration: pro-ulcerogenic action via 5-HT3 receptors and anti-ulcerogenic action via 5-HT4 receptors. Pharmacol Res. 2012 Sep;66(3):226-234. PMID: 22699012.

" "UN number: 2811     Class: 6.1     Packing Group: III

Proper shipping name: Toxic solid, organic, n.o.s. (Ketanserin)"

LKT K1678 Ketanserin 500 mg 600.1 5-HT2A antagonist, potential α1-adrenergic antagonist. 3-[2-[4-(4-Fluorobenzoyl)-1-piperidinyl]ethyl]-2,4[1H,3H]-quinazolinedione Perketan; Serefrex; Ketensin 74050-98-9 ≥97% 395.43 C22H22FN3O3 C1CN(CCC1C(=O)C2=CC=C(C=C2)F)CCN3C(=O)C4=CC=CC=C4NC3=O Ambient 4°C "Yu JG, Zhang EH, Liu AJ, et al. Ketanserin improves cardiac performance after myocardial infarction in spontaneously hypertensive rats partially through restoration of baroreflex function. Acta Pharmacol Sin. 2013 Dec;34(12):1508-14. PMID: 24241347.

 

Loyd DR, Chen PB, Hargreaves KM. Anti-hyperalgesic effects of anti-serotonergic compounds on serotonin- and capsaicin-evoked thermal hyperalgesia in the rat. Neuroscience. 2012 Feb 17;203:207-15. PMID: 22209919.

 

van Zwieten PA, Blauw GJ, van Brummelen P. Serotonergic receptors and drugs in hypertension. Pharmacol Toxicol. 1992 Jun;70(6 Pt 2):S17-22. PMID: 1354865.

 

Koss MC. Mechanism of ketanserin-induced sympatho-inhibition. Eur J Pharmacol. 1991 Mar 5;194(2-3):161-6. PMID: 1676374.

 

Kato S, Matsuda N, Matsumoto K, et al. Dual role of serotonin in the pathogenesis of indomethacin-induced small intestinal ulceration: pro-ulcerogenic action via 5-HT3 receptors and anti-ulcerogenic action via 5-HT4 receptors. Pharmacol Res. 2012 Sep;66(3):226-234. PMID: 22699012.

" "UN number: 2811     Class: 6.1     Packing Group: III

Proper shipping name: Toxic solid, organic, n.o.s. (Ketanserin)"

LKT K1776 Ketotifen Fumarate 500 mg 47.6 H1 histamine and LT antagonist, PDE inhibitor. "4,9-Dihydro-4-(1-methyl-4-piperidylidene)-10H-

benzo[4,5]cyclohepta[1,2-b]thiophen-10-one fumarate" Allerkif; Totifen; Zaditen; Zasten 34580-14-8 ≥98% 425.5 C19H19NOS C4H4O4 CN1CCC(=C2C3=C(C(=O)CC4=CC=CC=C42)SC=C3)CC1.C(=CC(=O)O)C(=O)O Ambient Ambient Soluble in water. "Zhang A, Chi X, Luo G, et al. Mast cell stabilization alleviates acute lung injury after orthotopic autologous liver transplantation in rats by downregulating inflammation. PLoS One. 2013 Oct 8;8(10):e75262. PMID: 24116032.

 

Doligalska M. Effect of ketotifen on the immune response in BALB/c mice infected with Trichinella spiralis. Wiad Parazytol. 2000;46(2):217-24. PMID: 16886340.

" Xn Not dangerous goods.

LKT K1776 Ketotifen Fumarate 1 g 67.9 H1 histamine and LT antagonist, PDE inhibitor. "4,9-Dihydro-4-(1-methyl-4-piperidylidene)-10H-

benzo[4,5]cyclohepta[1,2-b]thiophen-10-one fumarate" Allerkif; Totifen; Zaditen; Zasten 34580-14-8 ≥98% 425.5 C19H19NOS C4H4O4 CN1CCC(=C2C3=C(C(=O)CC4=CC=CC=C42)SC=C3)CC1.C(=CC(=O)O)C(=O)O Ambient Ambient Soluble in water. "Zhang A, Chi X, Luo G, et al. Mast cell stabilization alleviates acute lung injury after orthotopic autologous liver transplantation in rats by downregulating inflammation. PLoS One. 2013 Oct 8;8(10):e75262. PMID: 24116032.

 

Doligalska M. Effect of ketotifen on the immune response in BALB/c mice infected with Trichinella spiralis. Wiad Parazytol. 2000;46(2):217-24. PMID: 16886340.

" Xn Not dangerous goods.

LKT K2412 KGDS 1 mg 60 Synthetic peptide, fibrinogen derivative; glycoprotein IIb/IIIa agonist. ≥95% 405.41 C15H27N5O8 Ambient -20°C "Knapp A, Degenhardt T, Dodt J. Hirudisins. Hirudin-derived thrombin inhibitors with disintegrin activity. J Biol Chem. 1992 Dec 5;267(34):24230-4. PMID: 1447173.

 

Parise LV, Helgerson SL, Steiner B, et al. Synthetic peptides derived from fibrinogen and fibronectin change the conformation of purified platelet glycoprotein IIb-IIIa. J Biol Chem. 1987 Sep 15;262(26):12597-602. PMID: 2957377.

"

LKT K2412 KGDS 2 mg 101.9 Synthetic peptide, fibrinogen derivative; glycoprotein IIb/IIIa agonist. ≥95% 405.41 C15H27N5O8 Ambient -20°C "Knapp A, Degenhardt T, Dodt J. Hirudisins. Hirudin-derived thrombin inhibitors with disintegrin activity. J Biol Chem. 1992 Dec 5;267(34):24230-4. PMID: 1447173.

 

Parise LV, Helgerson SL, Steiner B, et al. Synthetic peptides derived from fibrinogen and fibronectin change the conformation of purified platelet glycoprotein IIb-IIIa. J Biol Chem. 1987 Sep 15;262(26):12597-602. PMID: 2957377.

"

LKT K2412 KGDS 5 mg 180 Synthetic peptide, fibrinogen derivative; glycoprotein IIb/IIIa agonist. ≥95% 405.41 C15H27N5O8 Ambient -20°C "Knapp A, Degenhardt T, Dodt J. Hirudisins. Hirudin-derived thrombin inhibitors with disintegrin activity. J Biol Chem. 1992 Dec 5;267(34):24230-4. PMID: 1447173.

 

Parise LV, Helgerson SL, Steiner B, et al. Synthetic peptides derived from fibrinogen and fibronectin change the conformation of purified platelet glycoprotein IIb-IIIa. J Biol Chem. 1987 Sep 15;262(26):12597-602. PMID: 2957377.

"

LKT K3352 Kinetensin 1 mg 60 Peptide, neurotensin analog. 103131-69-7 ≥95% 1172.4 C56H85N17O11 CCC(C)C(C(=O)NC(C)C(=O)NC(CCCN=C(N)N)C(=O)NC(CCCN=C(N)N)C(=O)NC(CC1=CN=CN1)C(=O)N2CCCC2C(=O)NC(CC3=CC=C(C=C3)O)C(=O)NC(CC4=CC=CC=C4)C(=O)NC(CC(C)C)C(=O)O)N Ambient -20°C "Read D, Shulkes A, Fletcher D, et al. Pharmacokinetics and biological activity of kinetensin in conscious sheep. Agents Actions. 1993 Mar;38(3-4):231-9. PMID: 8213349.

 

Sydbom A, Ware J, Mogard MH. Stimulation of histamine release by the peptide kinetensin. Agents Actions. 1989 Apr;27(1-2):68-71. PMID: 2473637.

" Not dangerous goods.

LKT K3352 Kinetensin 2 mg 101.9 Peptide, neurotensin analog. 103131-69-7 ≥95% 1172.4 C56H85N17O11 CCC(C)C(C(=O)NC(C)C(=O)NC(CCCN=C(N)N)C(=O)NC(CCCN=C(N)N)C(=O)NC(CC1=CN=CN1)C(=O)N2CCCC2C(=O)NC(CC3=CC=C(C=C3)O)C(=O)NC(CC4=CC=CC=C4)C(=O)NC(CC(C)C)C(=O)O)N Ambient -20°C "Read D, Shulkes A, Fletcher D, et al. Pharmacokinetics and biological activity of kinetensin in conscious sheep. Agents Actions. 1993 Mar;38(3-4):231-9. PMID: 8213349.

 

Sydbom A, Ware J, Mogard MH. Stimulation of histamine release by the peptide kinetensin. Agents Actions. 1989 Apr;27(1-2):68-71. PMID: 2473637.

" Not dangerous goods.

LKT K3352 Kinetensin 5 mg 180 Peptide, neurotensin analog. 103131-69-7 ≥95% 1172.4 C56H85N17O11 CCC(C)C(C(=O)NC(C)C(=O)NC(CCCN=C(N)N)C(=O)NC(CCCN=C(N)N)C(=O)NC(CC1=CN=CN1)C(=O)N2CCCC2C(=O)NC(CC3=CC=C(C=C3)O)C(=O)NC(CC4=CC=CC=C4)C(=O)NC(CC(C)C)C(=O)O)N Ambient -20°C "Read D, Shulkes A, Fletcher D, et al. Pharmacokinetics and biological activity of kinetensin in conscious sheep. Agents Actions. 1993 Mar;38(3-4):231-9. PMID: 8213349.

 

Sydbom A, Ware J, Mogard MH. Stimulation of histamine release by the peptide kinetensin. Agents Actions. 1989 Apr;27(1-2):68-71. PMID: 2473637.

" Not dangerous goods.

LKT K4401 KL-1 Peptide 1 mg 120 Peptide, c-Kit ligand fragment. ≥95% 1239.4 C53H90N16O18 Ambient -20°C "El Kossi MM, Haylor JL, Johnson TS, et al. Stem cell factor in a rat model of serum nephrotoxic nephritis. Nephron Exp Nephrol. 2008;108(1):e1-e10. PMID: 18087173.

 

Koller MR, Oxender M, Brott DA, et al. flt-3 ligand is more potent than c-kit ligand for the synergistic stimulation of ex vivo hematopoietic cell expansion. J Hematother. 1996 Oct;5(5):449-59. PMID: 8938517.

"

LKT K4401 KL-1 Peptide 2 mg 204.1 Peptide, c-Kit ligand fragment. ≥95% 1239.4 C53H90N16O18 Ambient -20°C "El Kossi MM, Haylor JL, Johnson TS, et al. Stem cell factor in a rat model of serum nephrotoxic nephritis. Nephron Exp Nephrol. 2008;108(1):e1-e10. PMID: 18087173.

 

Koller MR, Oxender M, Brott DA, et al. flt-3 ligand is more potent than c-kit ligand for the synergistic stimulation of ex vivo hematopoietic cell expansion. J Hematother. 1996 Oct;5(5):449-59. PMID: 8938517.

"

LKT K4401 KL-1 Peptide 5 mg 359.9 Peptide, c-Kit ligand fragment. ≥95% 1239.4 C53H90N16O18 Ambient -20°C "El Kossi MM, Haylor JL, Johnson TS, et al. Stem cell factor in a rat model of serum nephrotoxic nephritis. Nephron Exp Nephrol. 2008;108(1):e1-e10. PMID: 18087173.

 

Koller MR, Oxender M, Brott DA, et al. flt-3 ligand is more potent than c-kit ligand for the synergistic stimulation of ex vivo hematopoietic cell expansion. J Hematother. 1996 Oct;5(5):449-59. PMID: 8938517.

"

LKT K6864 KRQHPG 0.5 mg 48 Peptide, thyrotropin-releasing hormone progenitor fragment. thyrotropin-releasing hormone progenitor peptide ≥95% 721.82 C30H51N13O8 Ambient -20°C "Aoki Y, Ono H, Yasuo S, et al. Molecular evolution of prepro-thyrotropin-releasing hormone in the chicken (Gallus gallus) and its expression in the brain. Zoolog Sci. 2007 Jul;24(7):686-92. PMID: 17824776.

 

Mitsuma T, Hirooka Y, Nogimori T. Effects of dexamethasone on TRH and TRH precursor peptide (Lys-Arg-Gln-His-Pro-Gly-Arg-Arg) levels in various rat organs. Endocr Regul. 1992 Mar;26(1):29-34. PMID: 1421205.

"

LKT K6864 KRQHPG 1 mg 81 Peptide, thyrotropin-releasing hormone progenitor fragment. thyrotropin-releasing hormone progenitor peptide ≥95% 721.82 C30H51N13O8 Ambient -20°C "Aoki Y, Ono H, Yasuo S, et al. Molecular evolution of prepro-thyrotropin-releasing hormone in the chicken (Gallus gallus) and its expression in the brain. Zoolog Sci. 2007 Jul;24(7):686-92. PMID: 17824776.

 

Mitsuma T, Hirooka Y, Nogimori T. Effects of dexamethasone on TRH and TRH precursor peptide (Lys-Arg-Gln-His-Pro-Gly-Arg-Arg) levels in various rat organs. Endocr Regul. 1992 Mar;26(1):29-34. PMID: 1421205.

"

LKT K6864 KRQHPG 2.5 mg 144 Peptide, thyrotropin-releasing hormone progenitor fragment. thyrotropin-releasing hormone progenitor peptide ≥95% 721.82 C30H51N13O8 Ambient -20°C "Aoki Y, Ono H, Yasuo S, et al. Molecular evolution of prepro-thyrotropin-releasing hormone in the chicken (Gallus gallus) and its expression in the brain. Zoolog Sci. 2007 Jul;24(7):686-92. PMID: 17824776.

 

Mitsuma T, Hirooka Y, Nogimori T. Effects of dexamethasone on TRH and TRH precursor peptide (Lys-Arg-Gln-His-Pro-Gly-Arg-Arg) levels in various rat organs. Endocr Regul. 1992 Mar;26(1):29-34. PMID: 1421205.

"

LKT K9858 Kyotorphin 5 mg 120 Opioid neuropeptide; kyotorphin agonist. 70904-56-2 ≥95% 337.4 C15H23N5O4 C1=CC(=CC=C1CC(C(=O)NC(CCCN=C(N)N)C(=O)O)N)O Ambient -20°C "Miguel M, Manso M, Aleixandre A, et al. Vascular effects, angiotensin I-converting enzyme (ACE)-inhibitory activity, and antihypertensive properties of peptides derived from egg white. J Agric Food Chem. 2007 Dec 26;55(26):10615-21. PMID: 18047278.

 

Ueda H, Inoue M. In vivo signal transduction of nociceptive response by kyotorphin (tyrosine-arginine) through Galpha(i)- and inositol trisphosphate-mediated Ca(2+) influx. Mol Pharmacol. 2000 Jan;57(1):108-15. PMID: 10617685.

 

Satoh M, Wada T, Iwama T, et al. Sites of analgesic actions of kyotorphin and D-kyotorphin in the central nervous system of rats. Neuropeptides. 1985 Feb;5(4-6):415-8. PMID: 4000414.

" Not dangerous goods.

LKT K9858 Kyotorphin 10 mg 204.1 Opioid neuropeptide; kyotorphin agonist. 70904-56-2 ≥95% 337.4 C15H23N5O4 C1=CC(=CC=C1CC(C(=O)NC(CCCN=C(N)N)C(=O)O)N)O Ambient -20°C "Miguel M, Manso M, Aleixandre A, et al. Vascular effects, angiotensin I-converting enzyme (ACE)-inhibitory activity, and antihypertensive properties of peptides derived from egg white. J Agric Food Chem. 2007 Dec 26;55(26):10615-21. PMID: 18047278.

 

Ueda H, Inoue M. In vivo signal transduction of nociceptive response by kyotorphin (tyrosine-arginine) through Galpha(i)- and inositol trisphosphate-mediated Ca(2+) influx. Mol Pharmacol. 2000 Jan;57(1):108-15. PMID: 10617685.

 

Satoh M, Wada T, Iwama T, et al. Sites of analgesic actions of kyotorphin and D-kyotorphin in the central nervous system of rats. Neuropeptides. 1985 Feb;5(4-6):415-8. PMID: 4000414.

" Not dangerous goods.

LKT K9858 Kyotorphin 25 mg 359.9 Opioid neuropeptide; kyotorphin agonist. 70904-56-2 ≥95% 337.4 C15H23N5O4 C1=CC(=CC=C1CC(C(=O)NC(CCCN=C(N)N)C(=O)O)N)O Ambient -20°C "Miguel M, Manso M, Aleixandre A, et al. Vascular effects, angiotensin I-converting enzyme (ACE)-inhibitory activity, and antihypertensive properties of peptides derived from egg white. J Agric Food Chem. 2007 Dec 26;55(26):10615-21. PMID: 18047278.

 

Ueda H, Inoue M. In vivo signal transduction of nociceptive response by kyotorphin (tyrosine-arginine) through Galpha(i)- and inositol trisphosphate-mediated Ca(2+) influx. Mol Pharmacol. 2000 Jan;57(1):108-15. PMID: 10617685.

 

Satoh M, Wada T, Iwama T, et al. Sites of analgesic actions of kyotorphin and D-kyotorphin in the central nervous system of rats. Neuropeptides. 1985 Feb;5(4-6):415-8. PMID: 4000414.

" Not dangerous goods.

LKT Q8016 Quercetin Dihydrate 25 g 35.6 Flavonoid found in fruits, vegetables, and grains; RT, MAO, calcineurin inhibitor. 4 H- 1-Benzopyran-4-one-2-(3,4-dihydroxyphenyl)- 3,5,7-trihydroxy-dihydrate CCRIS 3304 6151-25-3 ≥95% 338.26 C15H10O7 2H2O C1=CC(=C(C=C1C2=C(C(=O)C3=C(C=C(C=C3O2)O)O)O)O)O.O.O Ambient 4°C Soluble in ethanol. Insoluble in water. "Pisonero-Vaquero S, García-Mediavilla MV, Jorquera F, et al. Modulation of PI3K-LXRα-dependent lipogenesis mediated by oxidative/nitrosative stress contributes to inhibition of HCV replication by quercetin. Lab Invest. 2014 Mar;94(3):262-74. PMID: 24492281.

 

Park HJ, Lee CM, Jung ID, et al. Quercetin regulates Th1/Th2 balance in a murine model of asthma. Int Immunopharmacol. 2009 Mar;9(3):261-7. PMID: 19061976.

 

Saaby L, Rasmussen HB, Jäger AK. MAO-A inhibitory activity of quercetin from Calluna vulgaris (L.) Hull. J Ethnopharmacol. 2009 Jan 12;121(1):178-81. PMID: 19013512.

 

Stewart LK, Soileau JL, Ribnicky D, et al. Quercetin transiently increases energy expenditure but persistently decreases circulating markers of inflammation in C57BL/6J mice fed a high-fat diet. Metabolism. 2008 Jul;57(7 Suppl 1):S39-46. PMID: 18555853.

 

Edwards RL, Lyon T, Litwin SE, et al. Quercetin reduces blood pressure in hypertensive subjects. J Nutr. 2007 Nov;137(11):2405-11. PMID: 17951477.

 

Spedding G, Ratty A, Middleton E Jr. Inhibition of reverse transcriptases by flavonoids. Antiviral Res. 1989 Sep;12(2):99-110. PMID: 2480745.

" T "UN number: 2811     Class:  6.1     Packing group:  III

Proper shipping name:  toxic solids, organic, n.o.s. (3,3’,4’,5,7-Pentahydroxyflavone dihydrate)

Marine pollutant:  No     Poison inhalation hazard:  No."

LKT Q8016 Quercetin Dihydrate 100 g 106.8 Flavonoid found in fruits, vegetables, and grains; RT, MAO, calcineurin inhibitor. 4 H- 1-Benzopyran-4-one-2-(3,4-dihydroxyphenyl)- 3,5,7-trihydroxy-dihydrate CCRIS 3304 6151-25-3 ≥95% 338.26 C15H10O7 2H2O C1=CC(=C(C=C1C2=C(C(=O)C3=C(C=C(C=C3O2)O)O)O)O)O.O.O Ambient 4°C Soluble in ethanol. Insoluble in water. "Pisonero-Vaquero S, García-Mediavilla MV, Jorquera F, et al. Modulation of PI3K-LXRα-dependent lipogenesis mediated by oxidative/nitrosative stress contributes to inhibition of HCV replication by quercetin. Lab Invest. 2014 Mar;94(3):262-74. PMID: 24492281.

 

Park HJ, Lee CM, Jung ID, et al. Quercetin regulates Th1/Th2 balance in a murine model of asthma. Int Immunopharmacol. 2009 Mar;9(3):261-7. PMID: 19061976.

 

Saaby L, Rasmussen HB, Jäger AK. MAO-A inhibitory activity of quercetin from Calluna vulgaris (L.) Hull. J Ethnopharmacol. 2009 Jan 12;121(1):178-81. PMID: 19013512.

 

Stewart LK, Soileau JL, Ribnicky D, et al. Quercetin transiently increases energy expenditure but persistently decreases circulating markers of inflammation in C57BL/6J mice fed a high-fat diet. Metabolism. 2008 Jul;57(7 Suppl 1):S39-46. PMID: 18555853.

 

Edwards RL, Lyon T, Litwin SE, et al. Quercetin reduces blood pressure in hypertensive subjects. J Nutr. 2007 Nov;137(11):2405-11. PMID: 17951477.

 

Spedding G, Ratty A, Middleton E Jr. Inhibition of reverse transcriptases by flavonoids. Antiviral Res. 1989 Sep;12(2):99-110. PMID: 2480745.

" T "UN number: 2811     Class:  6.1     Packing group:  III

Proper shipping name:  toxic solids, organic, n.o.s. (3,3’,4’,5,7-Pentahydroxyflavone dihydrate)

Marine pollutant:  No     Poison inhalation hazard:  No."

LKT Q8133 Quinacrine Dihydrochloride Dihydrate 10 g 106.9 Cell membrane permeability modulator, topoisomerase inhibitor. N4-(6-Chloro-2-methoxy-9-acridinyl)-N1,N1-diethyl-1,-4-pentanediamine dihydrochloride dihydrate Atebrine hydrochloride; RP-866; SN-390; Mepacrine 6151-30-0 ≥97% 508.92 C23H30ClN3O 2HCl 2H2O CCN(CC)CCCC(C)NC1=C2C=C(C=CC2=NC3=C1C=CC(=C3)Cl)OC.O.O.Cl.Cl Ambient Ambient Soluble in hot water. Slightly soluble in ethanol, methanol or water. Insoluble in ether, benzene or acetone. "Mohapatra P, Preet R, Das D, et al. Quinacrine-mediated autophagy and apoptosis in colon cancer cells is through a p53- and p21-dependent mechanism. Oncol Res. 2012;20(2-3):81-91. PMID: 23193914.

 

Gorbachev AV, Gasparian AV, Gurova KV, et al. Quinacrine inhibits the epidermal dendritic cell migration initiating T cell-mediated skin inflammation. Eur J Immunol. 2007 Aug;37(8):2257-67. PMID: 17634953.

 

Fasanmade AA, Owuor ED, Ee RP, et al. Quinacrine induces cytochrome c-dependent apoptotic signaling in human cervical carcinoma cells. Arch Pharm Res. 2001 Apr;24(2):126-35. PMID: 11339632.

" Xn, Xi Not dangerous goods.

LKT Q8133 Quinacrine Dihydrochloride Dihydrate 25 g 224.3 Cell membrane permeability modulator, topoisomerase inhibitor. N4-(6-Chloro-2-methoxy-9-acridinyl)-N1,N1-diethyl-1,-4-pentanediamine dihydrochloride dihydrate Atebrine hydrochloride; RP-866; SN-390; Mepacrine 6151-30-0 ≥97% 508.92 C23H30ClN3O 2HCl 2H2O CCN(CC)CCCC(C)NC1=C2C=C(C=CC2=NC3=C1C=CC(=C3)Cl)OC.O.O.Cl.Cl Ambient Ambient Soluble in hot water. Slightly soluble in ethanol, methanol or water. Insoluble in ether, benzene or acetone. "Mohapatra P, Preet R, Das D, et al. Quinacrine-mediated autophagy and apoptosis in colon cancer cells is through a p53- and p21-dependent mechanism. Oncol Res. 2012;20(2-3):81-91. PMID: 23193914.

 

Gorbachev AV, Gasparian AV, Gurova KV, et al. Quinacrine inhibits the epidermal dendritic cell migration initiating T cell-mediated skin inflammation. Eur J Immunol. 2007 Aug;37(8):2257-67. PMID: 17634953.

 

Fasanmade AA, Owuor ED, Ee RP, et al. Quinacrine induces cytochrome c-dependent apoptotic signaling in human cervical carcinoma cells. Arch Pharm Res. 2001 Apr;24(2):126-35. PMID: 11339632.

" Xn, Xi Not dangerous goods.

LKT Q8134 Quinapril Hydrochloride 100 mg 63.8 ACE inhibitor. (3S)-2-[(2S)-2-[[(1S)-1-(Ethoxycarbonyl)-3- phenylpropyl]amino]-1-oxopropyl]-1,2,3,4-tetrahydro-3-isoquinolinecarboxylic acid hydrochloride Accupril; Accuprin; Accupro; Acequin; Acuitel; Korec; Quinazil 82586-55-8 ≥98% 474.99 C25H30N2O5 HCl CCOC(=O)C(CCC1=CC=CC=C1)NC(C)C(=O)N2CC3=CC=CC=C3CC2C(=O)O.Cl Ambient Ambient Soluble in water (31mg/mL). "Brower GL, Levick SP, Janicki JS. Inhibition of matrix metalloproteinase activity by ACE inhibitors prevents left ventricular remodeling in a rat model of heart failure. Am J Physiol Heart Circ Physiol. 2007 Jun;292(6):H3057-64. PMID: 17308006.

 

We GC, Siroi MG, Qu R, et al. Effects of quinapril on myocardial function, ventricular remodeling and cardiac cytokine expression in congestive heart failure in the rat. Cardiovasc Drugs Ther. 2002 Jan;16(1):29-36. PMID: 12085975.

" None Not dangerous goods.

LKT Q8134 Quinapril Hydrochloride 500 mg 190.8 ACE inhibitor. (3S)-2-[(2S)-2-[[(1S)-1-(Ethoxycarbonyl)-3- phenylpropyl]amino]-1-oxopropyl]-1,2,3,4-tetrahydro-3-isoquinolinecarboxylic acid hydrochloride Accupril; Accuprin; Accupro; Acequin; Acuitel; Korec; Quinazil 82586-55-8 ≥98% 474.99 C25H30N2O5 HCl CCOC(=O)C(CCC1=CC=CC=C1)NC(C)C(=O)N2CC3=CC=CC=C3CC2C(=O)O.Cl Ambient Ambient Soluble in water (31mg/mL). "Brower GL, Levick SP, Janicki JS. Inhibition of matrix metalloproteinase activity by ACE inhibitors prevents left ventricular remodeling in a rat model of heart failure. Am J Physiol Heart Circ Physiol. 2007 Jun;292(6):H3057-64. PMID: 17308006.

 

We GC, Siroi MG, Qu R, et al. Effects of quinapril on myocardial function, ventricular remodeling and cardiac cytokine expression in congestive heart failure in the rat. Cardiovasc Drugs Ther. 2002 Jan;16(1):29-36. PMID: 12085975.

" None Not dangerous goods.

LKT Q8134 Quinapril Hydrochloride 1 g 305 ACE inhibitor. (3S)-2-[(2S)-2-[[(1S)-1-(Ethoxycarbonyl)-3- phenylpropyl]amino]-1-oxopropyl]-1,2,3,4-tetrahydro-3-isoquinolinecarboxylic acid hydrochloride Accupril; Accuprin; Accupro; Acequin; Acuitel; Korec; Quinazil 82586-55-8 ≥98% 474.99 C25H30N2O5 HCl CCOC(=O)C(CCC1=CC=CC=C1)NC(C)C(=O)N2CC3=CC=CC=C3CC2C(=O)O.Cl Ambient Ambient Soluble in water (31mg/mL). "Brower GL, Levick SP, Janicki JS. Inhibition of matrix metalloproteinase activity by ACE inhibitors prevents left ventricular remodeling in a rat model of heart failure. Am J Physiol Heart Circ Physiol. 2007 Jun;292(6):H3057-64. PMID: 17308006.

 

We GC, Siroi MG, Qu R, et al. Effects of quinapril on myocardial function, ventricular remodeling and cardiac cytokine expression in congestive heart failure in the rat. Cardiovasc Drugs Ther. 2002 Jan;16(1):29-36. PMID: 12085975.

" None Not dangerous goods.

LKT Q4370 QKRPSQRSKYL 1 mg 72.1 Peptide, PKC substrate. MBP 3-14 peptide ≥95% 1390.62 C60H103N21O17 Ambient -20°C Andrea JE, Sutherland C, Winter CK, et al. Substrate-dependent activation requirements and kinetic properties of protein kinase C. FEBS Lett. 1998 Jun 5;429(1):73-7. PMID: 9657386. Not dangerous goods.

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